230844:Aqp7
gene id: 230844:Aqp7
uniprot id: A0A6I9L9Q6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

230844:LOC102927647
gene id: 230844:LOC102927647
uniprot id: A0A6I9LS50
names: Similarity
messages: Belongs to the type-B carboxylesterase/lipase family.

230844:LOC102907262
gene id: 230844:LOC102907262
uniprot id: A0A6J0E541
names: Similarity
messages: Belongs to the arylamine N-acetyltransferase family.

230844:Maneal
gene id: 230844:Maneal
uniprot id: A0A6J0DH21
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 99 family.
messages: Golgi apparatus membrane
messages: Membrane

230844:Fkbp4
gene id: 230844:Fkbp4
uniprot id: A0A6I9M1L0
names: Subcellular Location Annotation
messages: Mitochondrion
messages: cytoskeleton
messages: cytosol

230844:LOC102923052
gene id: 230844:LOC102923052
uniprot id: A0A6I9ME98
names: Similarity
messages: Belongs to the MHC class I family.

230844:Fabp6
gene id: 230844:Fabp6
uniprot id: A0A6I9L1K3
names: Similarity
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.

230844:Mylk
gene id: 230844:Mylk
uniprot id: A0A6J0D1U3
uniprot id: A0A6J0D2J2
names: Similarity
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family.

230844:Mcoln3
gene id: 230844:Mcoln3
uniprot id: A0A6J0DTT2
names: Subcellular Location Annotation
messages: Endosome membrane
messages: Membrane

230844:Txnrd1
gene id: 230844:Txnrd1
uniprot id: A0A6I9L9X5
uniprot id: A0A6J0DE45
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

230844:LOC102915310
gene id: 230844:LOC102915310
uniprot id: A0A6I9M7Y7
names: Similarity
messages: Belongs to the cytochrome P450 family.

230844:Slc15a2
gene id: 230844:Slc15a2
uniprot id: A0A6I9LAG5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Apical cell membrane
messages: Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.
messages: Interacts (via extracellular domain region) with trypsin.
messages: Membrane

230844:Nrn1l
gene id: 230844:Nrn1l
uniprot id: A0A6J0DZN3
names: Similarity
messages: Belongs to the neuritin family.

230844:Sec63
gene id: 230844:Sec63
uniprot id: A0A6J0DNU8
names: Subcellular Location Annotation
messages: Membrane

230844:Cass4
gene id: 230844:Cass4
uniprot id: A0A6J0DXG2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CAS family.
messages: focal adhesion

230844:Rps15
gene id: 230844:Rps15
uniprot id: A0A6I9LFG9
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Component of the small ribosomal subunit.

230844:Nlgn3
gene id: 230844:Nlgn3
uniprot id: A0A6I9LE21
uniprot id: A0A6I9LLC9
uniprot id: A0A6I9LRI0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type-B carboxylesterase/lipase family.
messages: Cell membrane
messages: Membrane

230844:LOC102916720
gene id: 230844:LOC102916720
uniprot id: A0A6I9MP71
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:LOC102918115
gene id: 230844:LOC102918115
uniprot id: A0A6I9M930
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:LOC102914994
gene id: 230844:LOC102914994
uniprot id: A0A6J0EGA7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Matk
gene id: 230844:Matk
uniprot id: A0A6I9LFD1
uniprot id: A0A6I9LJI0
names: Similarity
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.

230844:LOC102925197
gene id: 230844:LOC102925197
uniprot id: A0A6I9M1W0
names: Function
names: Subunit
messages: In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins.
messages: Interacts with hair keratins.

230844:Asb14
gene id: 230844:Asb14
uniprot id: A0A6I9LEP8
names: Similarity
messages: Belongs to the ankyrin SOCS box (ASB) family.

230844:Mrps36
gene id: 230844:Mrps36
uniprot id: A0A6I9LH23
names: Subcellular Location Annotation
messages: Mitochondrion

230844:LOC102916738
gene id: 230844:LOC102916738
uniprot id: A0A6I9LLR6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:LOC102908789
gene id: 230844:LOC102908789
uniprot id: A0A6I9LHJ3
names: Similarity
messages: Belongs to the formin homology family. Cappuccino subfamily.

230844:Cxcl10
gene id: 230844:Cxcl10
uniprot id: A0A6I9M464
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the intercrine alpha (chemokine CxC) family.
messages: Secreted

230844:Pnrc2
gene id: 230844:Pnrc2
uniprot id: A0A6I9LAE2
names: Subcellular Location Annotation
messages: Nucleus

230844:Chrnb2
gene id: 230844:Chrnb2
uniprot id: A0A6I9L4A0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

230844:LOC102924256
gene id: 230844:LOC102924256
uniprot id: A0A6J0E4Q2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycoprotein hormones subunit beta family.
messages: Secreted

230844:Churc1
gene id: 230844:Churc1
uniprot id: A0A6I9KY64
names: Similarity
messages: Belongs to the Churchill family.

230844:Egfl7
gene id: 230844:Egfl7
uniprot id: A0A6J0DPT7
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

230844:Col4a3
gene id: 230844:Col4a3
uniprot id: A0A6I9MAF3
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Type IV collagen is the major structural component of glomerular basement membranes (GBM), forming a 'chicken-wire' meshwork together with laminins, proteoglycans and entactin/nidogen.
messages: basement membrane

230844:Unc119b
gene id: 230844:Unc119b
uniprot id: A0A6I9M454
names: Similarity
messages: Belongs to the PDE6D/unc-119 family.

230844:LOC102914155
gene id: 230844:LOC102914155
uniprot id: A0A6I9M3Q9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Cdcp2
gene id: 230844:Cdcp2
uniprot id: A0A6I9L622
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

230844:Rin2
gene id: 230844:Rin2
uniprot id: A0A6J0DSY8
uniprot id: A0A6J0DUT0
names: Similarity
messages: Belongs to the RIN (Ras interaction/interference) family.

230844:LOC102905144
gene id: 230844:LOC102905144
uniprot id: A0A6I9MLS4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Mtmr3
gene id: 230844:Mtmr3
uniprot id: A0A6I9KXT7
uniprot id: A0A6I9L4S6
uniprot id: A0A6I9L801
uniprot id: A0A6J0CXY0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily.
messages: Cytoplasm
messages: Membrane

230844:Slc10a2
gene id: 230844:Slc10a2
uniprot id: A0A6I9M6I5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bile acid:sodium symporter (BASS) (TC 2.A.28) family.
messages: Membrane

230844:Pelp1
gene id: 230844:Pelp1
uniprot id: A0A6I9MHE3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RIX1/PELP1 family.
messages: Cytoplasm
messages: Nucleus

230844:Ska2
gene id: 230844:Ska2
uniprot id: A0A6I9MRH5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SKA2 family.
messages: spindle

230844:Hspa4
gene id: 230844:Hspa4
uniprot id: A0A6I9MKT8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the heat shock protein 70 family.
messages: Cytoplasm
messages: Interacts with TJP1/ZO-1.

230844:Fam24b
gene id: 230844:Fam24b
uniprot id: A0A6J0D990
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAM24 family.
messages: Secreted

230844:Awat1
gene id: 230844:Awat1
uniprot id: A0A6I9LE36
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the diacylglycerol acyltransferase family.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

230844:Kat2a
gene id: 230844:Kat2a
uniprot id: A0A6I9LYQ8
uniprot id: A0A6I9MEZ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetyltransferase family. GCN5 subfamily.
messages: Nucleus
messages: centrosome

230844:Traf1
gene id: 230844:Traf1
uniprot id: A0A6I9LR87
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TNF receptor-associated factor family.
messages: Cytoplasm

230844:Emx2
gene id: 230844:Emx2
uniprot id: A0A6I9LFY7
names: Subcellular Location Annotation
messages: Nucleus

230844:Epha7
gene id: 230844:Epha7
uniprot id: A0A6I9M7X1
uniprot id: A0A6I9MBZ2
uniprot id: A0A6J0EH70
names: Subcellular Location Annotation
messages: Membrane

230844:Ubl3
gene id: 230844:Ubl3
uniprot id: A0A6I9LI64
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

230844:Tm9sf4
gene id: 230844:Tm9sf4
uniprot id: A0A6I9LVC4
uniprot id: A0A6I9M0R5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nonaspanin (TM9SF) (TC 9.A.2) family.
messages: Membrane

230844:Tgm1
gene id: 230844:Tgm1
uniprot id: A0A6J0E2F0
names: Cofactor
names: Similarity
messages: Belongs to the transglutaminase superfamily. Transglutaminase family.
messages: Binds 1 Ca(2+) ion per subunit.

230844:LOC102918139
gene id: 230844:LOC102918139
uniprot id: A0A6I9MJ31
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Reep2
gene id: 230844:Reep2
uniprot id: A0A6I9L6A6
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DP1 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

230844:Tmeff2
gene id: 230844:Tmeff2
uniprot id: A0A6I9L0Z2
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

230844:S100a1
gene id: 230844:S100a1
uniprot id: A0A6I9L461
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the S-100 family.
messages: Cytoplasm
messages: Mitochondrion

230844:Kcng1
gene id: 230844:Kcng1
uniprot id: A0A6I9M883
names: Subcellular Location Annotation
messages: Membrane

230844:LOC102922980
gene id: 230844:LOC102922980
uniprot id: A0A6I9MHL9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Mapk8ip3
gene id: 230844:Mapk8ip3
uniprot id: A0A6I9KV56
uniprot id: A0A6I9KVJ8
uniprot id: A0A6I9L1N4
uniprot id: A0A6I9L227
uniprot id: A0A6I9L537
uniprot id: A0A6J0DXR5
uniprot id: A0A6J0DZF0
uniprot id: A0A6J0E0R0
uniprot id: A0A6J0E5Z3
names: Similarity
messages: Belongs to the JIP scaffold family.

230844:LOC102915805
gene id: 230844:LOC102915805
uniprot id: A0A6I9M7K1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

230844:Lox
gene id: 230844:Lox
uniprot id: A0A6I9LSI5
uniprot id: A0A6I9M0M1
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lysyl oxidase family.
messages: Mediates the post-translational oxidative deamination of lysine residues on target proteins leading to the formation of deaminated lysine (allysine).
messages: The lysine tyrosylquinone cross-link (LTQ) is generated by condensation of the epsilon-amino group of a lysine with a topaquinone produced by oxidation of tyrosine.
messages: extracellular space

230844:Krt14
gene id: 230844:Krt14
uniprot id: A0A6I9MC77
names: Similarity
messages: Belongs to the intermediate filament family.

230844:Prok1
gene id: 230844:Prok1
uniprot id: A0A6I9LJ33
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AVIT (prokineticin) family.
messages: Secreted

230844:Vps33b
gene id: 230844:Vps33b
uniprot id: A0A6I9KY75
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STXBP/unc-18/SEC1 family.
messages: Early endosome
messages: Endosome membrane
messages: Late endosome membrane
messages: Lysosome membrane
messages: clathrin-coated vesicle

230844:Cmklr1
gene id: 230844:Cmklr1
uniprot id: A0A6J0EE17
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Belongs to the chemokine-like receptor (CMKLR) family.
messages: Cell membrane
messages: Membrane

230844:Gins4
gene id: 230844:Gins4
uniprot id: A0A6I9LHK1
uniprot id: A0A6I9LR20
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GINS4/SLD5 family.
messages: Chromosome
messages: Nucleus
messages: Required for initiation of chromosomal DNA replication. Core component of CDC45-MCM-GINS (CMG) helicase, the molecular machine that unwinds template DNA during replication, and around which the replisome is built.

230844:Rpl10a
gene id: 230844:Rpl10a
uniprot id: A0A6I9LG77
names: Similarity
messages: Belongs to the universal ribosomal protein uL1 family.

230844:Nppc
gene id: 230844:Nppc
uniprot id: A0A6I9LTE2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the natriuretic peptide family.
messages: Secreted

230844:Tex28
gene id: 230844:Tex28
uniprot id: A0A6I9LXX8
names: Similarity
messages: Belongs to the TEX28 family.

230844:Tbx5
gene id: 230844:Tbx5
uniprot id: A0A6I9KZZ2
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

230844:Gnai2
gene id: 230844:Gnai2
uniprot id: A0A6I9LGA0
names: Similarity
messages: Belongs to the G-alpha family. G(i/o/t/z) subfamily.

230844:LOC102924478
gene id: 230844:LOC102924478
uniprot id: A0A6I9M3K9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:LOC102905512
gene id: 230844:LOC102905512
uniprot id: A0A6I9LVL9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2B family.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

230844:Dmd
gene id: 230844:Dmd
uniprot id: A0A6J0E7S5
names: Subcellular Location Annotation
messages: cytoskeleton

230844:Rhpn1
gene id: 230844:Rhpn1
uniprot id: A0A6I9LWI6
uniprot id: A0A6J0E9V9
uniprot id: A0A6J0EBT5
names: Similarity
messages: Belongs to the RHPN family.

230844:LOC102921986
gene id: 230844:LOC102921986
uniprot id: A0A6I9M4V6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Aquaporins facilitate the transport of water and small neutral solutes across cell membranes.
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family. AQP11/AQP12 subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

230844:Susd1
gene id: 230844:Susd1
uniprot id: A0A6I9MC22
uniprot id: A0A6J0CIG8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

230844:LOC102914158
gene id: 230844:LOC102914158
uniprot id: A0A6I9MAG4
names: Similarity
messages: Belongs to the aldo/keto reductase family.

230844:Cd99l2
gene id: 230844:Cd99l2
uniprot id: A0A6I9LA68
uniprot id: A0A6J0D3W0
names: Similarity
messages: Belongs to the CD99 family.

230844:Pdk3
gene id: 230844:Pdk3
uniprot id: A0A6I9M9Z6
uniprot id: A0A6J0EC87
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PDK/BCKDK protein kinase family.
messages: Mitochondrion matrix

230844:Plscr4
gene id: 230844:Plscr4
uniprot id: A0A6J0DZZ5
names: Function
names: Similarity
messages: Belongs to the phospholipid scramblase family.
messages: May mediate accelerated ATP-independent bidirectional transbilayer migration of phospholipids upon binding calcium ions that results in a loss of phospholipid asymmetry in the plasma membrane.

230844:B3gnt8
gene id: 230844:B3gnt8
uniprot id: A0A6J0E197
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane

230844:Pcyt1b
gene id: 230844:Pcyt1b
uniprot id: A0A6I9LYP0
uniprot id: A0A6I9M5U4
uniprot id: A0A6J0EA05
names: Function
names: Similarity
messages: Belongs to the cytidylyltransferase family.
messages: Catalyzes the key rate-limiting step in the CDP-choline pathway for phosphatidylcholine biosynthesis.

230844:Parg
gene id: 230844:Parg
uniprot id: A0A6I9LCI7
uniprot id: A0A6J0D6F4
uniprot id: A0A6J0D8M0
names: Similarity
messages: Belongs to the poly(ADP-ribose) glycohydrolase family.

230844:Aatf
gene id: 230844:Aatf
uniprot id: A0A6I9LHX7
uniprot id: A0A6I9LRH7
names: Similarity
messages: Belongs to the AATF family.

230844:LOC102924804
gene id: 230844:LOC102924804
uniprot id: A0A6I9M6S3
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

230844:LOC102908547
gene id: 230844:LOC102908547
uniprot id: A0A6I9KWJ3
names: Subcellular Location Annotation
messages: Nucleus

230844:LOC102911507
gene id: 230844:LOC102911507
uniprot id: A0A6J0DT36
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Sh3glb1
gene id: 230844:Sh3glb1
uniprot id: A0A6J0DXT6
uniprot id: A0A6J0E4B1
names: Subcellular Location Annotation
messages: Golgi apparatus membrane
messages: Midbody
messages: Mitochondrion outer membrane
messages: autophagosome membrane

230844:Mtrfr
gene id: 230844:Mtrfr
uniprot id: A0A6I9KZW5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Mitochondrion

230844:LOC107399549
gene id: 230844:LOC107399549
uniprot id: A0A6J0CM53
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IGFL family.
messages: Secreted

230844:Jakmip1
gene id: 230844:Jakmip1
uniprot id: A0A6I9LVU1
uniprot id: A0A6J0DVP2
uniprot id: A0A6J0DY42
names: Similarity
messages: Belongs to the JAKMIP family.

230844:Map2k4
gene id: 230844:Map2k4
uniprot id: A0A6J0CZP2
uniprot id: A0A6J0D2Q8
names: Similarity
messages: Belongs to the protein kinase superfamily.

230844:Best2
gene id: 230844:Best2
uniprot id: A0A6I9MK37
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anion channel-forming bestrophin (TC 1.A.46) family. Calcium-sensitive chloride channel subfamily.
messages: Cell membrane
messages: Forms calcium-sensitive chloride channels. Permeable to bicarbonate.
messages: Membrane

230844:Ywhab
gene id: 230844:Ywhab
uniprot id: A0A6I9KUG7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 14-3-3 family.
messages: Cytoplasm

230844:Ric3
gene id: 230844:Ric3
uniprot id: A0A6I9L7H4
uniprot id: A0A6I9LGT4
names: Similarity
messages: Belongs to the ric-3 family.

230844:Fbxo9
gene id: 230844:Fbxo9
uniprot id: A0A6J0CZJ3
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Part of the SCF (SKP1-CUL1-F-box) E3 ubiquitin-protein ligase complex SCF(FBXO9) composed of CUL1, SKP1, RBX1 and FBXO9. Interacts with TTI1 and TELO2; when TTI1 and TELO2 are phosphorylated by CK2.
messages: Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins and plays a role in several biological processes such as cell cycle, cell proliferation, or maintenance of chromosome stability. Ubiquitinates mTORC1-bound TTI1 and TELO2 when they are phosphorylated by CK2 following growth factor deprivation, leading to their degradation. In contrast, does not mediate ubiquitination of TTI1 and TELO2 when they are part of the mTORC2 complex. As a consequence, mTORC1 is inactivated to restrain cell growth and protein translation, while mTORC2 is the activated due to the relief of feedback inhibition by mTORC1. Plays a role in maintaining epithelial cell survival by regulating the turn-over of chromatin modulator PRMT4 through ubiquitination and degradation by the proteasomal pathway. Regulates also PPARgamma stability by facilitating PPARgamma/PPARG ubiquitination and thereby plays a role in adipocyte differentiation.

230844:LOC102917633
gene id: 230844:LOC102917633
uniprot id: A0A6I9MP82
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Slc10a7
gene id: 230844:Slc10a7
uniprot id: A0A6J0E1V8
uniprot id: A0A6J0E4Y2
uniprot id: A0A6J0E503
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bile acid:sodium symporter (BASS) (TC 2.A.28) family.
messages: Cell membrane
messages: Does not show transport activity towards bile acids or steroid sulfates.
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane

230844:Scarf1
gene id: 230844:Scarf1
uniprot id: A0A6I9LDV6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

230844:Taf13
gene id: 230844:Taf13
uniprot id: A0A6I9LHW7
names: Subcellular Location Annotation
messages: Nucleus

230844:Tfap2d
gene id: 230844:Tfap2d
uniprot id: A0A6I9LWK2
names: Similarity
messages: Belongs to the AP-2 family.

230844:Icam5
gene id: 230844:Icam5
uniprot id: A0A6I9LRD0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the immunoglobulin superfamily. ICAM family.
messages: Membrane

230844:Foxl3
gene id: 230844:Foxl3
uniprot id: A0A6I9M4S7
names: Subcellular Location Annotation
messages: Nucleus

230844:LOC102915048
gene id: 230844:LOC102915048
uniprot id: A0A6I9MPD8
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.

230844:Plxnb1
gene id: 230844:Plxnb1
uniprot id: A0A6J0DA21
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the plexin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

230844:Hoxa1
gene id: 230844:Hoxa1
uniprot id: A0A6I9LPM6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Antp homeobox family. Labial subfamily.
messages: Nucleus

230844:LOC102905320
gene id: 230844:LOC102905320
uniprot id: A0A6J0DNI0
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family.

230844:Pi4k2a
gene id: 230844:Pi4k2a
uniprot id: A0A6I9LZG8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PI3/PI4-kinase family. Type II PI4K subfamily.
messages: Membrane

230844:Mall
gene id: 230844:Mall
uniprot id: A0A6I9LQ29
names: Subcellular Location Annotation
messages: Membrane

230844:LOC102909281
gene id: 230844:LOC102909281
uniprot id: A0A6I9MFV9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Mrpl24
gene id: 230844:Mrpl24
uniprot id: A0A6I9L4H6
names: Similarity
messages: Belongs to the universal ribosomal protein uL24 family.

230844:Tmem265
gene id: 230844:Tmem265
uniprot id: A0A6J0D9D9
names: Similarity
messages: Belongs to the CD225/Dispanin family.

230844:LOC102920455
gene id: 230844:LOC102920455
uniprot id: A0A6I9M507
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Gaa
gene id: 230844:Gaa
uniprot id: A0A6I9LTW6
uniprot id: A0A6I9M4R0
names: Caution
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

230844:Gjb2
gene id: 230844:Gjb2
uniprot id: A0A6I9M2Z0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family. Beta-type (group I) subfamily.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

230844:LOC102923061
gene id: 230844:LOC102923061
uniprot id: A0A6I9MDK9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Ankrd65
gene id: 230844:Ankrd65
uniprot id: A0A6I9M410
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.

230844:Pax8
gene id: 230844:Pax8
uniprot id: A0A6I9LM92
uniprot id: A0A6J0DGU9
uniprot id: A0A6J0DJB0
uniprot id: A0A6J0DQ69
names: Subcellular Location Annotation
messages: Nucleus

230844:Ap1b1
gene id: 230844:Ap1b1
uniprot id: A0A6I9KXU7
uniprot id: A0A6I9L4G8
uniprot id: A0A6I9L4T5
uniprot id: A0A6I9L811
uniprot id: A0A6J0CXF6
names: Similarity
messages: Belongs to the adaptor complexes large subunit family.

230844:Cd247
gene id: 230844:Cd247
uniprot id: A0A6I9M0H3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CD3Z/FCER1G family.
messages: Cell membrane
messages: Membrane

230844:LOC102908808
gene id: 230844:LOC102908808
uniprot id: A0A6I9M3P5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Aars1
gene id: 230844:Aars1
uniprot id: A0A6I9L6Z1
names: Cofactor
names: Domain
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Alax-L subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: ISGylated.
messages: Monomer. Interacts with ANKRD16; the interaction is direct.

230844:Phex
gene id: 230844:Phex
uniprot id: A0A6I9L8M9
names: Subcellular Location Annotation
messages: Membrane

230844:LOC102914398
gene id: 230844:LOC102914398
uniprot id: A0A6I9MIH7
names: Similarity
messages: Belongs to the 'GDXG' lipolytic enzyme family.

230844:Plxnb3
gene id: 230844:Plxnb3
uniprot id: A0A6J0CGB6
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the plexin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

230844:Enkd1
gene id: 230844:Enkd1
uniprot id: A0A6I9LYD0
uniprot id: A0A6J0E0X8
names: Subcellular Location Annotation
messages: cilium axoneme

230844:Mrpl58
gene id: 230844:Mrpl58
uniprot id: A0A6I9MF62
names: Subcellular Location Annotation
messages: Mitochondrion

230844:Sbds
gene id: 230844:Sbds
uniprot id: A0A6I9KUK3
names: Function
names: Similarity
messages: Belongs to the SDO1/SBDS family.
messages: Required for the assembly of mature ribosomes and ribosome biogenesis. Together with EFL1, triggers the GTP-dependent release of EIF6 from 60S pre-ribosomes in the cytoplasm, thereby activating ribosomes for translation competence by allowing 80S ribosome assembly and facilitating EIF6 recycling to the nucleus, where it is required for 60S rRNA processing and nuclear export. Required for normal levels of protein synthesis. May play a role in cellular stress resistance. May play a role in cellular response to DNA damage. May play a role in cell proliferation.

230844:LOC102926133
gene id: 230844:LOC102926133
uniprot id: A0A6I9M087
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PMG family.
messages: In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins.
messages: Interacts with hair keratins.

230844:Ehd3
gene id: 230844:Ehd3
uniprot id: A0A6I9MAY9
names: Subcellular Location Annotation
messages: Cell membrane
messages: Endosome membrane
messages: Membrane

230844:Dipk2a
gene id: 230844:Dipk2a
uniprot id: A0A6I9LX41
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DIPK family.
messages: Secreted

230844:Sod2
gene id: 230844:Sod2
uniprot id: A0A6I9L7T4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.
messages: Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems.
messages: Homotetramer.
messages: Mitochondrion matrix

230844:Tmem151b
gene id: 230844:Tmem151b
uniprot id: A0A6J0DVL6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM151 family.
messages: Membrane

230844:Cacng2
gene id: 230844:Cacng2
uniprot id: A0A6I9M2U0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily.
messages: Membrane
messages: Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Thought to stabilize the calcium channel in an inactivated (closed) state.

230844:LOC102913987
gene id: 230844:LOC102913987
uniprot id: A0A6I9MHS3
names: Subcellular Location Annotation
messages: Nucleus

230844:Slc44a2
gene id: 230844:Slc44a2
uniprot id: A0A6I9LN51
uniprot id: A0A6I9LZD1
uniprot id: A0A6I9M3Q5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CTL (choline transporter-like) family.
messages: Cell membrane
messages: Choline transporter.
messages: Membrane

230844:Slc35d1
gene id: 230844:Slc35d1
uniprot id: A0A6I9LZ14
names: Subcellular Location Annotation
messages: Membrane

230844:Cntn2
gene id: 230844:Cntn2
uniprot id: A0A6I9M7D0
names: Similarity
messages: Belongs to the immunoglobulin superfamily. Contactin family.

230844:Snx2
gene id: 230844:Snx2
uniprot id: A0A6I9LNZ3
uniprot id: A0A6J0E4G0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sorting nexin family.
messages: Early endosome membrane
messages: Endosome membrane
messages: Membrane
messages: lamellipodium

230844:LOC102917843
gene id: 230844:LOC102917843
uniprot id: A0A6I9MKB7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:LOC102928350
gene id: 230844:LOC102928350
uniprot id: A0A6I9LXW1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Fuca1
gene id: 230844:Fuca1
uniprot id: A0A6I9LE30
names: Function
names: Similarity
names: Subunit
messages: Alpha-L-fucosidase is responsible for hydrolyzing the alpha-1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins.
messages: Belongs to the glycosyl hydrolase 29 family.
messages: Homotetramer.

230844:Bcl7c
gene id: 230844:Bcl7c
uniprot id: A0A6I9L4Q3
uniprot id: A0A6I9LD55
uniprot id: A0A6I9LD98
uniprot id: A0A6I9LH41
names: Similarity
messages: Belongs to the BCL7 family.

230844:Epn2
gene id: 230844:Epn2
uniprot id: A0A6I9KYQ3
uniprot id: A0A6I9L5U1
uniprot id: A0A6J0CXH5
uniprot id: A0A6J0CZU2
names: Similarity
messages: Belongs to the epsin family.

230844:Gabra1
gene id: 230844:Gabra1
uniprot id: A0A6J0E589
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family. Gamma-aminobutyric acid receptor (TC 1.A.9.5) subfamily. GABRA1 sub-subfamily.
messages: Cell membrane
messages: Cytoplasmic vesicle membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

230844:Snrpb
gene id: 230844:Snrpb
uniprot id: A0A6I9LYG5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the snRNP SmB/SmN family.
messages: Nucleus

230844:Asb15
gene id: 230844:Asb15
uniprot id: A0A6J0E3X7
names: Similarity
messages: Belongs to the ankyrin SOCS box (ASB) family.

230844:Mtmr4
gene id: 230844:Mtmr4
uniprot id: A0A6I9LGD3
uniprot id: A0A6J0DR14
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily.
messages: Cytoplasm
messages: Membrane

230844:LOC102921450
gene id: 230844:LOC102921450
uniprot id: A0A6I9LCD6
names: Subcellular Location Annotation
messages: nucleoplasm

230844:LOC102904934
gene id: 230844:LOC102904934
uniprot id: A0A6J0CS38
uniprot id: A0A6J0CTY1
names: Similarity
messages: Belongs to the TCAF family.

230844:Irf6
gene id: 230844:Irf6
uniprot id: A0A6J0E363
uniprot id: A0A6J0E4R3
names: Subcellular Location Annotation
messages: Nucleus

230844:Lpar2
gene id: 230844:Lpar2
uniprot id: A0A6I9MK33
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Pfkfb3
gene id: 230844:Pfkfb3
uniprot id: A0A6I9LTN8
uniprot id: A0A6I9LYU6
uniprot id: A0A6I9M5Y3
uniprot id: A0A6I9MA38
uniprot id: A0A6J0E6J9
uniprot id: A0A6J0E6K4
uniprot id: A0A6J0E8E1
uniprot id: A0A6J0E8E7
uniprot id: A0A6J0EA95
uniprot id: A0A6J0EAA3
uniprot id: A0A6J0EE01
names: Similarity
messages: In the C-terminal section; belongs to the phosphoglycerate mutase family.

230844:Chmp1a
gene id: 230844:Chmp1a
uniprot id: A0A6I9LSA5
names: Similarity
messages: Belongs to the SNF7 family.

230844:Ndufb3
gene id: 230844:Ndufb3
uniprot id: A0A6I9L939
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFB3 subunit family.
messages: Mitochondrion inner membrane

230844:Erbin
gene id: 230844:Erbin
uniprot id: A0A6I9LQL1
names: Similarity
messages: Belongs to the LAP (LRR and PDZ) protein family.

230844:LOC102905510
gene id: 230844:LOC102905510
uniprot id: A0A6I9M192
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Smad6
gene id: 230844:Smad6
uniprot id: A0A6I9KUP8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dwarfin/SMAD family.
messages: Cytoplasm
messages: Nucleus

230844:Hoxb3
gene id: 230844:Hoxb3
uniprot id: A0A6J0EA22
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Antp homeobox family.
messages: Nucleus

230844:Sh3bgrl2
gene id: 230844:Sh3bgrl2
uniprot id: A0A6J0DWM5
names: Similarity
messages: Belongs to the SH3BGR family.

230844:Mapk9
gene id: 230844:Mapk9
uniprot id: A0A6I9LN91
uniprot id: A0A6I9LRI8
uniprot id: A0A6I9LYV7
uniprot id: A0A6I9M3Y0
uniprot id: A0A6J0DYL4
uniprot id: A0A6J0E0G0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MAP kinase subfamily.
messages: Cytoplasm
messages: Responds to activation by environmental stress and pro-inflammatory cytokines by phosphorylating a number of transcription factors, and thus regulates transcriptional activity.

230844:Dnase1l3
gene id: 230844:Dnase1l3
uniprot id: A0A6I9MIN3
names: Similarity
messages: Belongs to the DNase I family.

230844:Mms22l
gene id: 230844:Mms22l
uniprot id: A0A6J0DCN9
uniprot id: A0A6J0DF17
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MMS22 family. MMS22L subfamily.
messages: Chromosome
messages: Nucleus

230844:Khdrbs1
gene id: 230844:Khdrbs1
uniprot id: A0A6I9MHU8
names: Similarity
messages: Belongs to the KHDRBS family.

230844:Snx25
gene id: 230844:Snx25
uniprot id: A0A6J0DEM2
names: Similarity
messages: Belongs to the sorting nexin family.

230844:LOC102923554
gene id: 230844:LOC102923554
uniprot id: A0A6I9M2Q3
names: Similarity
messages: Belongs to the cytochrome P450 family.

230844:Trex1
gene id: 230844:Trex1
uniprot id: A0A6I9L6Y3
names: Similarity
messages: Belongs to the exonuclease superfamily. TREX family.

230844:LOC102919071
gene id: 230844:LOC102919071
uniprot id: A0A6I9MM71
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:LOC102913368
gene id: 230844:LOC102913368
uniprot id: A0A6I9MFY0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

230844:Slc6a11
gene id: 230844:Slc6a11
uniprot id: A0A6I9M2A4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

230844:LOC102929154
gene id: 230844:LOC102929154
uniprot id: A0A6J0E635
names: Domain
names: Function
names: Similarity
messages: Belongs to the DEAD box helicase family. eIF4A subfamily.
messages: RNA helicase.
messages: The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.

230844:Sh2b3
gene id: 230844:Sh2b3
uniprot id: A0A6I9KZW8
names: Similarity
messages: Belongs to the SH2B adapter family.

230844:Nup98
gene id: 230844:Nup98
uniprot id: A0A6I9LZL8
uniprot id: A0A6I9MFS4
uniprot id: A0A6J0CHV5
uniprot id: A0A6J0CIH5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleoporin GLFG family.
messages: Nucleus membrane
messages: nuclear pore complex

230844:Msra
gene id: 230844:Msra
uniprot id: A0A6I9LRC2
uniprot id: A0A6J0EAQ3
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.

230844:Tekt5
gene id: 230844:Tekt5
uniprot id: A0A6I9LHN3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tektin family.
messages: Microtubule inner protein (MIP) part of the dynein-decorated doublet microtubules (DMTs) in cilia and flagellar axoneme. Forms filamentous polymers in the walls of ciliary and flagellar microtubules. Required for normal sperm mobility.
messages: flagellum

230844:Scnn1a
gene id: 230844:Scnn1a
uniprot id: A0A6I9M8A4
names: Subcellular Location Annotation
messages: Membrane

230844:Nhej1
gene id: 230844:Nhej1
uniprot id: A0A6J0CH24
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the XRCC4-XLF family. XLF subfamily.
messages: Nucleus

230844:Sh3bgrl3
gene id: 230844:Sh3bgrl3
uniprot id: A0A6I9LAA3
names: Similarity
messages: Belongs to the SH3BGR family.

230844:Asb17
gene id: 230844:Asb17
uniprot id: A0A6I9LSH8
names: Function
names: Similarity
messages: Belongs to the ankyrin SOCS box (ASB) family.
messages: May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.

230844:LOC102910517
gene id: 230844:LOC102910517
uniprot id: A0A6I9L8N4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Membrane
messages: tight junction

230844:Tle1
gene id: 230844:Tle1
uniprot id: A0A6I9LEL0
uniprot id: A0A6I9LLW0
uniprot id: A0A6I9LSA4
uniprot id: A0A6J0DHU8
uniprot id: A0A6J0DHV3
uniprot id: A0A6J0DHV4
uniprot id: A0A6J0DK99
uniprot id: A0A6J0DKD0
uniprot id: A0A6J0DKD6
uniprot id: A0A6J0DKD7
uniprot id: A0A6J0DKN5
uniprot id: A0A6J0DKP0
uniprot id: A0A6J0DRC4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat Groucho/TLE family.
messages: Nucleus

230844:Trim54
gene id: 230844:Trim54
uniprot id: A0A6I9M3H7
names: Function
names: Subcellular Location Annotation
messages: May bind and stabilize microtubules during myotubes formation.
messages: Z line

230844:Tmem182
gene id: 230844:Tmem182
uniprot id: A0A6I9M0N8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM182 family.
messages: Cell membrane
messages: Membrane

230844:Gjb3
gene id: 230844:Gjb3
uniprot id: A0A6I9LSD2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

230844:Rarb
gene id: 230844:Rarb
uniprot id: A0A6I9L1X0
uniprot id: A0A6J0D7T0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR1 subfamily.
messages: Nucleus

230844:Camlg
gene id: 230844:Camlg
uniprot id: A0A6I9L586
names: Function
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Required for the post-translational delivery of tail-anchored (TA) proteins to the endoplasmic reticulum. Together with GET1/WRB, acts as a membrane receptor for soluble GET3/TRC40, which recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. Required for the stability of GET1. Stimulates calcium signaling in T cells through its involvement in elevation of intracellular calcium. Essential for the survival of peripheral follicular B cells.

230844:LOC102905368
gene id: 230844:LOC102905368
uniprot id: A0A6I9LH07
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Olfml2a
gene id: 230844:Olfml2a
uniprot id: A0A6I9MBF2
uniprot id: A0A6J0CG81
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

230844:Gpr37
gene id: 230844:Gpr37
uniprot id: A0A6I9LUK7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

230844:Ldb1
gene id: 230844:Ldb1
uniprot id: A0A6I9LQC0
uniprot id: A0A6I9M6A7
uniprot id: A0A6J0E4Z0
names: Similarity
messages: Belongs to the LDB family.

230844:Atr
gene id: 230844:Atr
uniprot id: A0A6I9L9C7
names: Similarity
messages: Belongs to the PI3/PI4-kinase family. ATM subfamily.

230844:Tmem263
gene id: 230844:Tmem263
uniprot id: A0A6I9LR84
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM263 family.
messages: Membrane

230844:Atp5mg
gene id: 230844:Atp5mg
uniprot id: A0A6I9M3W0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase g subunit family.
messages: Membrane
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain. Minor subunit located with subunit a in the membrane.
messages: Mitochondrial membrane ATP synthase (F1F0 ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F1 - containing the extramembraneous catalytic core, and F0 - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F1 is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F0 domain. Minor subunit located with subunit a in the membrane.
messages: Mitochondrion

230844:LOC102919485
gene id: 230844:LOC102919485
uniprot id: A0A6I9MK19
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Dusp5
gene id: 230844:Dusp5
uniprot id: A0A6I9M2L0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.
messages: Nucleus

230844:Nox4
gene id: 230844:Nox4
uniprot id: A0A6I9MKI5
uniprot id: A0A6J0CPY2
uniprot id: A0A6J0CQR3
names: Subcellular Location Annotation
messages: Membrane

230844:Tctn3
gene id: 230844:Tctn3
uniprot id: A0A6I9LLJ2
names: Similarity
names: Subunit
messages: Belongs to the tectonic family.
messages: Part of the tectonic-like complex (also named B9 complex).

230844:Ogfod1
gene id: 230844:Ogfod1
uniprot id: A0A6I9LJU7
names: Similarity
messages: Belongs to the TPA1 family.

230844:Ruvbl2
gene id: 230844:Ruvbl2
uniprot id: A0A6I9LXG2
uniprot id: A0A6J0DZN7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RuvB family.
messages: Dynein axonemal particle
messages: Nucleus
messages: Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding.

230844:Pdrg1
gene id: 230844:Pdrg1
uniprot id: A0A6I9LVR5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the prefoldin subunit beta family.
messages: Component of the PAQosome complex which is responsible for the biogenesis of several protein complexes and which consists of R2TP complex members RUVBL1, RUVBL2, RPAP3 and PIH1D1, URI complex members PFDN2, PFDN6, PDRG1, UXT and URI1 as well as ASDURF, POLR2E and DNAAF10/WDR92.
messages: Cytoplasm
messages: May play a role in chaperone-mediated protein folding.

230844:Smad4
gene id: 230844:Smad4
uniprot id: A0A6I9KSZ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dwarfin/SMAD family.
messages: Cytoplasm
messages: Nucleus

230844:LOC107400139
gene id: 230844:LOC107400139
uniprot id: A0A6J0CSD2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Snx10
gene id: 230844:Snx10
uniprot id: A0A6J0DMM4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sorting nexin family.
messages: Membrane

230844:Abca6
gene id: 230844:Abca6
uniprot id: A0A6I9KST1
names: Subcellular Location Annotation
messages: Membrane

230844:Pthlh
gene id: 230844:Pthlh
uniprot id: A0A6I9LXY9
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the parathyroid hormone family.
messages: Cytoplasm
messages: Neuroendocrine peptide which is a critical regulator of cellular and organ growth, development, migration, differentiation and survival and of epithelial calcium ion transport. Regulates endochondral bone development and epithelial-mesenchymal interactions during the formation of the mammary glands and teeth. Required for skeletal homeostasis. Promotes mammary mesenchyme differentiation and bud outgrowth by modulating mesenchymal cell responsiveness to BMPs. Up-regulates BMPR1A expression in the mammary mesenchyme and this increases the sensitivity of these cells to BMPs and allows them to respond to BMP4 in a paracrine and/or autocrine fashion. BMP4 signaling in the mesenchyme, in turn, triggers epithelial outgrowth and augments MSX2 expression, which causes the mammary mesenchyme to inhibit hair follicle formation within the nipple sheath.
messages: Nucleus
messages: Osteostatin is a potent inhibitor of osteoclastic bone resorption.
messages: PTHrP interacts with PTH1R (via N-terminal extracellular domain).
messages: Secreted
messages: There are several secretory forms, including osteostatin, arising from endoproteolytic cleavage of the initial translation product. Each of these secretory forms is believed to have one or more of its own receptors that mediates the normal paracrine, autocrine and endocrine actions.

230844:Entpd8
gene id: 230844:Entpd8
uniprot id: A0A6J0DGT0
names: Similarity
messages: Belongs to the GDA1/CD39 NTPase family.

230844:Acmsd
gene id: 230844:Acmsd
uniprot id: A0A6I9LYW4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. ACMSD family.
messages: Converts alpha-amino-beta-carboxymuconate-epsilon-semialdehyde (ACMS) to alpha-aminomuconate semialdehyde (AMS). ACMS can be converted non-enzymatically to quinolate (QA), a key precursor of NAD, and a potent endogenous excitotoxin of neuronal cells which is implicated in the pathogenesis of various neurodegenerative disorders. In the presence of ACMSD, ACMS is converted to AMS, a benign catabolite. ACMSD ultimately controls the metabolic fate of tryptophan catabolism along the kynurenine pathway.
messages: Monomer.

230844:Galnt18
gene id: 230844:Galnt18
uniprot id: A0A6I9LG72
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
messages: Golgi apparatus membrane
messages: Membrane

230844:LOC102916367
gene id: 230844:LOC102916367
uniprot id: A0A6I9M976
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

230844:Dmc1
gene id: 230844:Dmc1
uniprot id: A0A6J0DE81
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family. DMC1 subfamily.
messages: May participate in meiotic recombination, specifically in homologous strand assimilation, which is required for the resolution of meiotic double-strand breaks.
messages: Nucleus

230844:Alg2
gene id: 230844:Alg2
uniprot id: A0A6I9L9N0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase group 1 family.
messages: Mannosylates Man(2)GlcNAc(2)-dolichol diphosphate and Man(1)GlcNAc(2)-dolichol diphosphate to form Man(3)GlcNAc(2)-dolichol diphosphate.
messages: Membrane

230844:LOC102907270
gene id: 230844:LOC102907270
uniprot id: A0A6I9M0C5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome c oxidase VIII family.
messages: Component of the cytochrome c oxidase (complex IV, CIV), a multisubunit enzyme composed of 14 subunits. The complex is composed of a catalytic core of 3 subunits MT-CO1, MT-CO2 and MT-CO3, encoded in the mitochondrial DNA, and 11 supernumerary subunits COX4I, COX5A, COX5B, COX6A, COX6B, COX6C, COX7A, COX7B, COX7C, COX8 and NDUFA4, which are encoded in the nuclear genome. The complex exists as a monomer or a dimer and forms supercomplexes (SCs) in the inner mitochondrial membrane with NADH-ubiquinone oxidoreductase (complex I, CI) and ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII), resulting in different assemblies (supercomplex SCI(1)III(2)IV(1) and megacomplex MCI(2)III(2)IV(2)).
messages: Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)). The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
messages: Membrane
messages: Mitochondrion inner membrane

230844:LOC102925021
gene id: 230844:LOC102925021
uniprot id: A0A6I9M695
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Ehd4
gene id: 230844:Ehd4
uniprot id: A0A6I9MBX6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Endosome membrane
messages: Membrane

230844:Dnah2
gene id: 230844:Dnah2
uniprot id: A0A6J0CY00
names: Similarity
messages: Belongs to the dynein heavy chain family.

230844:Folr1
gene id: 230844:Folr1
uniprot id: A0A6J0CHY5
names: Similarity
messages: Belongs to the folate receptor family.

230844:Sh3bp4
gene id: 230844:Sh3bp4
uniprot id: A0A6J0E679
names: Subcellular Location Annotation
messages: Nucleus
messages: Vesicle
messages: clathrin-coated pit
messages: clathrin-coated vesicle

230844:Syne2
gene id: 230844:Syne2
uniprot id: A0A6I9L560
uniprot id: A0A6J0CWD5
uniprot id: A0A6J0CY18
uniprot id: A0A6J0CYN7
uniprot id: A0A6J0CYP2
uniprot id: A0A6J0D1J6
names: Similarity
messages: Belongs to the nesprin family.

230844:Rpl24
gene id: 230844:Rpl24
uniprot id: A0A6I9MM32
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL24 family.

230844:Rcl1
gene id: 230844:Rcl1
uniprot id: A0A6I9M6D8
uniprot id: A0A6J0EAQ5
uniprot id: A0A6J0ECU2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA 3'-terminal cyclase family. Type 2 subfamily.
messages: Part of the small subunit (SSU) processome, composed of more than 70 proteins and the RNA chaperone small nucleolar RNA (snoRNA) U3.
messages: nucleolus

230844:LOC102920647
gene id: 230844:LOC102920647
uniprot id: A0A6I9LYT4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Nek8
gene id: 230844:Nek8
uniprot id: A0A6I9L5G2
names: Similarity
messages: Belongs to the protein kinase superfamily. NEK Ser/Thr protein kinase family. NIMA subfamily.

230844:Rab19
gene id: 230844:Rab19
uniprot id: A0A6J0E739
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Membrane

230844:Ssr3
gene id: 230844:Ssr3
uniprot id: A0A6I9KX56
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP-gamma family.
messages: Endoplasmic reticulum membrane
messages: Heterotetramer of TRAP-alpha, TRAP-beta, TRAP-delta and TRAP-gamma.
messages: Membrane
messages: TRAP proteins are part of a complex whose function is to bind calcium to the ER membrane and thereby regulate the retention of ER resident proteins.

230844:Gpr22
gene id: 230844:Gpr22
uniprot id: A0A6J0E4V8
names: Subcellular Location Annotation
messages: Membrane

230844:Slc30a8
gene id: 230844:Slc30a8
uniprot id: A0A6I9LNS6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily.
messages: Membrane

230844:Ihh
gene id: 230844:Ihh
uniprot id: A0A6I9KW44
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the hedgehog family.
messages: Cell membrane
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Membrane
messages: Multimer.
messages: The C-terminal part of the hedgehog protein precursor displays an autoproteolysis activity that results in the cleavage of the full-length protein into two parts (N-product and C-product). In addition, the C-terminal part displays a cholesterol transferase activity that results by the covalent attachment of a cholesterol moiety to the C-terminal of the newly generated N-product.
messages: The dually lipidated hedgehog protein N-product is a morphogen which is essential for a variety of patterning events during development.

230844:Mul1
gene id: 230844:Mul1
uniprot id: A0A6I9LDJ6
names: Subcellular Location Annotation
messages: Membrane

230844:LOC102926234
gene id: 230844:LOC102926234
uniprot id: A0A6I9LRG6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Elk3
gene id: 230844:Elk3
uniprot id: A0A6J0E9X5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

230844:Pabir2
gene id: 230844:Pabir2
uniprot id: A0A6I9LG94
uniprot id: A0A6I9LNK1
names: Similarity
messages: Belongs to the FAM122 family.

230844:Fgd5
gene id: 230844:Fgd5
uniprot id: A0A6I9L3K9
names: Subcellular Location Annotation
messages: cytoskeleton

230844:Fam110a
gene id: 230844:Fam110a
uniprot id: A0A6I9LKG1
names: Similarity
messages: Belongs to the FAM110 family.

230844:Spast
gene id: 230844:Spast
uniprot id: A0A6I9LZZ8
uniprot id: A0A6J0EFE6
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent microtubule severing protein that specifically recognizes and cuts microtubules that are polyglutamylated. Preferentially recognizes and acts on microtubules decorated with short polyglutamate tails: severing activity increases as the number of glutamates per tubulin rises from one to eight, but decreases beyond this glutamylation threshold. Severing activity is not dependent on tubulin acetylation or detyrosination. Microtubule severing promotes reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation. It is critical for the biogenesis and maintenance of complex microtubule arrays in axons, spindles and cilia. SPAST is involved in abscission step of cytokinesis and nuclear envelope reassembly during anaphase in cooperation with the ESCRT-III complex. Recruited at the midbody, probably by IST1, and participates in membrane fission during abscission together with the ESCRT-III complex. Recruited to the nuclear membrane by IST1 and mediates microtubule severing, promoting nuclear envelope sealing and mitotic spindle disassembly during late anaphase. Required for membrane traffic from the endoplasmic reticulum (ER) to the Golgi and endosome recycling. Recruited by IST1 to endosomes and regulates early endosomal tubulation and recycling by mediating microtubule severing. Probably plays a role in axon growth and the formation of axonal branches.
messages: Allosteric enzyme with a cooperative mechanism; at least two neighbor subunits influence each other strongly in spastin hexamers. Microtubule binding promotes cooperative interactions among spastin subunits.
messages: Belongs to the AAA ATPase family. Spastin subfamily.
messages: Cytoplasm
messages: Endoplasmic reticulum
messages: Homohexamer. Mostly monomeric, but assembles into hexameric structure for short periods of time. Oligomerization seems to be a prerequisite for catalytic activity. Binding to ATP in a cleft between two adjacent subunits stabilizes the homohexameric form. Binds to microtubules at least in part via the alpha-tubulin and beta-tubulin tails. The hexamer adopts a ring conformation through which microtubules pass prior to being severed. Does not interact strongly with tubulin heterodimers. Interacts (via MIT domain) with CHMP1B; the interaction is direct. Interacts with SSNA1. Interacts with ATL1. Interacts with RTN1. Interacts with ZFYVE27. Interacts with REEP1. Interacts (via MIT domain) with IST1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Midbody
messages: Nucleus
messages: centrosome
messages: cytoskeleton
messages: perinuclear region
messages: spindle

230844:Ocln
gene id: 230844:Ocln
uniprot id: A0A6J0DLI9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELL/occludin family.
messages: Cell membrane
messages: May play a role in the formation and regulation of the tight junction (TJ) paracellular permeability barrier.
messages: Membrane
messages: tight junction

230844:Slc25a14
gene id: 230844:Slc25a14
uniprot id: A0A6I9M5Z5
uniprot id: A0A6I9MMA1
uniprot id: A0A6J0CSY2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

230844:Slc6a2
gene id: 230844:Slc6a2
uniprot id: A0A6I9LHV7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

230844:LOC102926459
gene id: 230844:LOC102926459
uniprot id: A0A6I9L460
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIG1 family.
messages: Membrane

230844:Cuzd1
gene id: 230844:Cuzd1
uniprot id: A0A6I9LD48
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

230844:Tmem245
gene id: 230844:Tmem245
uniprot id: A0A6I9LJY7
uniprot id: A0A6I9M040
uniprot id: A0A6J0DTM3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

230844:Insl5
gene id: 230844:Insl5
uniprot id: A0A6I9M439
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the insulin family.
messages: Secreted

230844:LOC102925255
gene id: 230844:LOC102925255
uniprot id: A0A6I9M933
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Dync1li1
gene id: 230844:Dync1li1
uniprot id: A0A6I9KT76
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes.
messages: Belongs to the dynein light intermediate chain family.
messages: Homodimer. The cytoplasmic dynein 1 complex consists of two catalytic heavy chains (HCs) and a number of non-catalytic subunits presented by intermediate chains (ICs).
messages: cytoskeleton

230844:LOC102913549
gene id: 230844:LOC102913549
uniprot id: A0A6I9MCL8
names: Subcellular Location Annotation
messages: Secreted

230844:Ncan
gene id: 230844:Ncan
uniprot id: A0A6J0CS09
names: Caution
names: Similarity
messages: Belongs to the aggrecan/versican proteoglycan family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

230844:Sntg2
gene id: 230844:Sntg2
uniprot id: A0A6I9M9F5
uniprot id: A0A6J0ECV9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the syntrophin family.
messages: cytoskeleton

230844:Drd5
gene id: 230844:Drd5
uniprot id: A0A6I9LKP5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Ipo8
gene id: 230844:Ipo8
uniprot id: A0A6I9LML2
uniprot id: A0A6I9LYC9
uniprot id: A0A6I9M312
names: Subcellular Location Annotation
messages: Cytoplasm

230844:Arpin
gene id: 230844:Arpin
uniprot id: A0A6I9KSU0
uniprot id: A0A6J0CZZ9
names: Similarity
messages: Belongs to the Arpin family.

230844:LOC102907840
gene id: 230844:LOC102907840
uniprot id: A0A6I9MG14
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:LOC102905976
gene id: 230844:LOC102905976
uniprot id: A0A6I9MFW7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MHC class I family.
messages: Membrane

230844:Haspin
gene id: 230844:Haspin
uniprot id: A0A6I9LXK3
names: Subcellular Location Annotation
messages: Chromosome

230844:B3gnt7
gene id: 230844:B3gnt7
uniprot id: A0A6I9LK42
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane

230844:LOC102925106
gene id: 230844:LOC102925106
uniprot id: A0A6I9M963
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

230844:Napa
gene id: 230844:Napa
uniprot id: A0A6I9M700
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNAP family.
messages: Membrane
messages: Required for vesicular transport between the endoplasmic reticulum and the Golgi apparatus.

230844:LOC102915916
gene id: 230844:LOC102915916
uniprot id: A0A6J0E8H9
names: Similarity
messages: Belongs to the cyclin family.

230844:Mrto4
gene id: 230844:Mrto4
uniprot id: A0A6I9LKY0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associates with the pre-60S ribosomal particle.
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Component of the ribosome assembly machinery. Nuclear paralog of the ribosomal protein P0, it binds pre-60S subunits at an early stage of assembly in the nucleolus, and is replaced by P0 in cytoplasmic pre-60S subunits and mature 80S ribosomes.
messages: Cytoplasm
messages: nucleolus

230844:Snap25
gene id: 230844:Snap25
uniprot id: A0A6I9LXH8
uniprot id: A0A6J0DT14
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SNAP-25 family.
messages: Cell membrane
messages: Membrane
messages: Part of the SNARE core complex containing SNAP25, VAMP2 and STX1A; this complex binds CPLX1. Found in a complex containing SYT1, SV2B and syntaxin-1. Found in a ternary complex with STX1A and VAMP8. Interacts with HSC70 and with SYT9, forming a complex with DNAJC5. The interaction with SYT9 is inhibited in presence of calcium. Isoform 1 and isoform 2 interact with BLOC1S6. Interacts with CENPF. Interacts with EQTN. Interacts with HGS. Interacts with KCNB1 (via N-terminus); reduces the voltage-dependent potassium channel KCNB1 activity in pancreatic beta cells. Interacts with OTOF. Interacts with RIMS1. Interacts with SNAPIN. Interacts with STXBP6. Interacts with TRIM9. Interacts with ZDHHC13 (via ANK repeats). Interacts with ZDHHC17 (via ANK repeats). Associates with the BLOC-1 complex. Interacts with PLCL1 (via C2 domain). Interacts with PRRT2; this interaction may impair the formation of the SNARE complex. Interacts with alpha-synuclein/SNCA. Interacts with PRPH2. Interacts with ROM1. Interacts with STX3.
messages: Photoreceptor inner segment
messages: synaptosome
messages: t-SNARE involved in the molecular regulation of neurotransmitter release. Plays an important role in the synaptic function of specific neuronal systems. Associates with proteins involved in vesicle docking and membrane fusion. Regulates plasma membrane recycling through its interaction with CENPF. Modulates the gating characteristics of the delayed rectifier voltage-dependent potassium channel KCNB1 in pancreatic beta cells.

230844:Ercc3
gene id: 230844:Ercc3
uniprot id: A0A6I9LF08
names: Similarity
messages: Belongs to the helicase family. RAD25/XPB subfamily.

230844:Araf
gene id: 230844:Araf
uniprot id: A0A6I9LVY8
names: Similarity
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. RAF subfamily.

230844:Nup50
gene id: 230844:Nup50
uniprot id: A0A6I9LAK6
names: Subcellular Location Annotation
messages: nuclear pore complex

230844:Fmnl3
gene id: 230844:Fmnl3
uniprot id: A0A6J0CZH8
names: Similarity
messages: Belongs to the formin homology family.

230844:LOC102918121
gene id: 230844:LOC102918121
uniprot id: A0A6I9L358
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Interacts with IL8. Interacts with GNAI2.
messages: Membrane

230844:Rhpn2
gene id: 230844:Rhpn2
uniprot id: A0A6I9LJH3
uniprot id: A0A6J0DT01
names: Similarity
messages: Belongs to the RHPN family.

230844:LOC102909237
gene id: 230844:LOC102909237
uniprot id: A0A6J0CF20
names: Caution
names: Subcellular Location Annotation
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

230844:Hoxd3
gene id: 230844:Hoxd3
uniprot id: A0A6I9L3F4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Antp homeobox family.
messages: Nucleus

230844:Abca5
gene id: 230844:Abca5
uniprot id: A0A6J0D7A7
names: Subcellular Location Annotation
messages: Membrane

230844:LOC102908251
gene id: 230844:LOC102908251
uniprot id: A0A6I9LSS1
names: Subcellular Location Annotation
messages: Membrane

230844:LOC102928700
gene id: 230844:LOC102928700
uniprot id: A0A6I9MMN3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Vps33a
gene id: 230844:Vps33a
uniprot id: A0A6I9KZT4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STXBP/unc-18/SEC1 family.
messages: Early endosome
messages: Endosome membrane
messages: Late endosome membrane
messages: Lysosome membrane
messages: clathrin-coated vesicle

230844:Stxbp5l
gene id: 230844:Stxbp5l
uniprot id: A0A6I9L2E4
uniprot id: A0A6I9L344
uniprot id: A0A6I9LAH0
uniprot id: A0A6I9LAH1
uniprot id: A0A6J0D3N8
uniprot id: A0A6J0D4L8
uniprot id: A0A6J0D598
uniprot id: A0A6J0D5S7
uniprot id: A0A6J0D5T4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat L(2)GL family.
messages: Cell membrane
messages: Cytoplasm
messages: Membrane

230844:Lhfpl4
gene id: 230844:Lhfpl4
uniprot id: A0A6I9MJ83
names: Subcellular Location Annotation
messages: Membrane

230844:Taf12
gene id: 230844:Taf12
uniprot id: A0A6I9L259
uniprot id: A0A6I9LA54
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAF12 family.
messages: Nucleus

230844:Nedd9
gene id: 230844:Nedd9
uniprot id: A0A6I9KXI0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CAS family.
messages: focal adhesion

230844:Dmrt1
gene id: 230844:Dmrt1
uniprot id: A0A6I9LIH2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DMRT family.
messages: Nucleus

230844:Dph5
gene id: 230844:Dph5
uniprot id: A0A6I9LIU7
names: Function
names: Similarity
messages: Belongs to the diphthine synthase family.
messages: S-adenosyl-L-methionine-dependent methyltransferase that catalyzes four methylations of the modified target histidine residue in translation elongation factor 2 (EF-2), to form an intermediate called diphthine methyl ester. The four successive methylation reactions represent the second step of diphthamide biosynthesis.

230844:Slc17a7
gene id: 230844:Slc17a7
uniprot id: A0A6I9LPM8
names: Subcellular Location Annotation
messages: Membrane

230844:LOC102904775
gene id: 230844:LOC102904775
uniprot id: A0A6I9LPC4
names: Similarity
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. GB1/RHD3 GTPase family.

230844:Tnip2
gene id: 230844:Tnip2
uniprot id: A0A6I9M0X2
uniprot id: A0A6J0E2D1
names: Subcellular Location Annotation
messages: Cytoplasm

230844:Tmem8b
gene id: 230844:Tmem8b
uniprot id: A0A6I9M1R7
uniprot id: A0A6J0DXJ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM8 family.
messages: Cell membrane
messages: Membrane

230844:Hnrnpk
gene id: 230844:Hnrnpk
uniprot id: A0A6I9LDE6
uniprot id: A0A6I9LMD7
uniprot id: A0A6I9LT12
uniprot id: A0A6J0DKZ1
names: Subcellular Location Annotation
messages: Cytoplasm
messages: nucleoplasm
messages: podosome

230844:Cd79b
gene id: 230844:Cd79b
uniprot id: A0A6I9KSW5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

230844:Lmna
gene id: 230844:Lmna
uniprot id: A0A6I9L3J4
uniprot id: A0A6J0D5C6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the intermediate filament family.
messages: Nucleus lamina

230844:LOC102922106
gene id: 230844:LOC102922106
uniprot id: A0A6I9M171
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

230844:Grhl3
gene id: 230844:Grhl3
uniprot id: A0A6I9LAD9
names: Subcellular Location Annotation
messages: Nucleus

230844:Arpc4
gene id: 230844:Arpc4
uniprot id: A0A6I9MMZ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ARPC4 family.
messages: Cell projection
messages: Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the mother actin filament.
messages: cytoskeleton

230844:Ckb
gene id: 230844:Ckb
uniprot id: A0A6I9M5V9
names: Similarity
messages: Belongs to the ATP:guanido phosphotransferase family.

230844:Kcnc4
gene id: 230844:Kcnc4
uniprot id: A0A6I9L985
uniprot id: A0A6I9LJ28
names: Subcellular Location Annotation
messages: Membrane

230844:Psmd9
gene id: 230844:Psmd9
uniprot id: A0A6I9KZT8
names: Similarity
messages: Belongs to the proteasome subunit p27 family.

230844:Dpf2
gene id: 230844:Dpf2
uniprot id: A0A6I9LQG8
names: Similarity
messages: Belongs to the requiem/DPF family.

230844:Ddx54
gene id: 230844:Ddx54
uniprot id: A0A6I9KZY3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DEAD box helicase family. DDX54/DBP10 subfamily.
messages: nucleolus

230844:Ptges3l
gene id: 230844:Ptges3l
uniprot id: A0A6J0CGX7
uniprot id: A0A6J0CJJ8
names: Similarity
messages: Belongs to the p23/wos2 family.

230844:Idi1
gene id: 230844:Idi1
uniprot id: A0A6I9LPN7
uniprot id: A0A6J0E5L9
names: Function
names: Similarity
messages: Belongs to the IPP isomerase type 1 family.
messages: Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP).

230844:Supt5h
gene id: 230844:Supt5h
uniprot id: A0A6I9M2A7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPT5 family.
messages: Nucleus

230844:Cnn1
gene id: 230844:Cnn1
uniprot id: A0A6I9LNP4
names: Function
names: Similarity
messages: Belongs to the calponin family.
messages: Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity.

230844:Abcb8
gene id: 230844:Abcb8
uniprot id: A0A6I9M5A4
uniprot id: A0A6I9MGE5
names: Subcellular Location Annotation
messages: Membrane

230844:Rnf4
gene id: 230844:Rnf4
uniprot id: A0A6I9LVW8
names: Subcellular Location Annotation
messages: Nucleus

230844:Slc7a6os
gene id: 230844:Slc7a6os
uniprot id: A0A6I9LYX0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IWR1/SLC7A6OS family.
messages: Cytoplasm
messages: Directs RNA polymerase II nuclear import.
messages: Nucleus

230844:LOC102922709
gene id: 230844:LOC102922709
uniprot id: A0A6I9LSQ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S1 family.
messages: Membrane

230844:Romo1
gene id: 230844:Romo1
uniprot id: A0A6I9M6F6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MGR2 family.
messages: Has antibacterial activity against a variety of bacteria including S.aureus, P.aeruginosa and M.tuberculosis. Acts by inducing bacterial membrane breakage.
messages: Induces production of reactive oxygen species (ROS) which are necessary for cell proliferation. May play a role in inducing oxidative DNA damage and replicative senescence. May play a role in the coordination of mitochondrial morphology and cell proliferation.
messages: Mitochondrion inner membrane

230844:Tars2
gene id: 230844:Tars2
uniprot id: A0A6I9LGS5
uniprot id: A0A6J0DL23
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.

230844:Avpi1
gene id: 230844:Avpi1
uniprot id: A0A6I9M538
names: Function
messages: May be involved in MAP kinase activation, epithelial sodium channel (ENaC) down-regulation and cell cycling.

230844:Ireb2
gene id: 230844:Ireb2
uniprot id: A0A6I9KVF5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aconitase/IPM isomerase family.
messages: Cytoplasm

230844:Abcc4
gene id: 230844:Abcc4
uniprot id: A0A6I9L7T3
names: Subcellular Location Annotation
messages: Membrane

230844:Klrk1
gene id: 230844:Klrk1
uniprot id: A0A6J0CQ86
names: Subcellular Location Annotation
messages: Cell membrane

230844:Slco2b1
gene id: 230844:Slco2b1
uniprot id: A0A6I9LG09
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the organo anion transporter (TC 2.A.60) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

230844:Aqp11
gene id: 230844:Aqp11
uniprot id: A0A6I9LBI0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Aquaporins facilitate the transport of water and small neutral solutes across cell membranes.
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family. AQP11/AQP12 subfamily.
messages: Membrane

230844:Klc2
gene id: 230844:Klc2
uniprot id: A0A6I9LQB0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the kinesin light chain family.
messages: Kinesin is a microtubule-associated force-producing protein that play a role in organelle transport.
messages: Oligomeric complex composed of two heavy chains and two light chains.
messages: cytoskeleton

230844:Avil
gene id: 230844:Avil
uniprot id: A0A6I9KY77
names: Similarity
messages: Belongs to the villin/gelsolin family.

230844:Dlgap1
gene id: 230844:Dlgap1
uniprot id: A0A6I9KWJ7
uniprot id: A0A6I9L2X4
uniprot id: A0A6I9L395
uniprot id: A0A6I9L6I0
uniprot id: A0A6J0CF15
uniprot id: A0A6J0CHS2
uniprot id: A0A6J0CHU2
names: Similarity
messages: Belongs to the SAPAP family.

230844:Gpr37l1
gene id: 230844:Gpr37l1
uniprot id: A0A6I9LGJ7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

230844:LOC102923563
gene id: 230844:LOC102923563
uniprot id: A0A6J0DGF6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MAL family.
messages: Membrane

230844:Gimd1
gene id: 230844:Gimd1
uniprot id: A0A6I9KZ57
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily.

230844:Magoh
gene id: 230844:Magoh
uniprot id: A0A6I9L5X9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mago nashi family.
messages: Nucleus

230844:Polr1e
gene id: 230844:Polr1e
uniprot id: A0A6I9LLH2
uniprot id: A0A6J0E439
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic RPA49/POLR1E RNA polymerase subunit family.
messages: nucleolus

230844:Sting1
gene id: 230844:Sting1
uniprot id: A0A6I9M0N0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STING family.
messages: Endoplasmic reticulum-Golgi intermediate compartment membrane
messages: Mitochondrion outer membrane
messages: autophagosome membrane
messages: perinuclear region

230844:Yrdc
gene id: 230844:Yrdc
uniprot id: A0A6I9LK75
names: Similarity
messages: Belongs to the SUA5 family.

230844:Adrb1
gene id: 230844:Adrb1
uniprot id: A0A6I9LFX5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Pdss2
gene id: 230844:Pdss2
uniprot id: A0A6I9LPH5
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

230844:Gba
gene id: 230844:Gba
uniprot id: A0A6I9LBQ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 30 family.
messages: Lysosome membrane

230844:Dlat
gene id: 230844:Dlat
uniprot id: A0A6I9L6P7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 2 lipoyl cofactors covalently.
messages: Mitochondrion matrix
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).

230844:Cwc15
gene id: 230844:Cwc15
uniprot id: A0A6I9LUD9
names: Similarity
messages: Belongs to the CWC15 family.

230844:Npsr1
gene id: 230844:Npsr1
uniprot id: A0A6J0ECF0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily.
messages: Cell membrane
messages: Membrane

230844:LOC102907812
gene id: 230844:LOC102907812
uniprot id: A0A6I9M2X8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the intercrine beta (chemokine CC) family.
messages: Secreted

230844:Prpf4
gene id: 230844:Prpf4
uniprot id: A0A6I9LMR1
names: Subcellular Location Annotation
messages: Nucleus speckle

230844:Ppp1r14d
gene id: 230844:Ppp1r14d
uniprot id: A0A6I9LIB9
uniprot id: A0A6J0DCK4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PP1 inhibitor family.
messages: Cytoplasm
messages: Inhibitor of PPP1CA.
messages: Membrane

230844:LOC102917086
gene id: 230844:LOC102917086
uniprot id: A0A6I9M039
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Anxa10
gene id: 230844:Anxa10
uniprot id: A0A6I9M0S1
uniprot id: A0A6I9M4W5
names: Similarity
messages: Belongs to the annexin family.

230844:Rpl23
gene id: 230844:Rpl23
uniprot id: A0A6I9L234
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Component of the large ribosomal subunit.

230844:Lyrm9
gene id: 230844:Lyrm9
uniprot id: A0A6I9L6R3
names: Similarity
messages: Belongs to the complex I LYR family. LYRM9 subfamily.

230844:C10H4orf48
gene id: 230844:C10H4orf48
uniprot id: A0A6I9KXN2
uniprot id: A0A6J0CX13
names: Subcellular Location Annotation
messages: Secreted

230844:LOC102908338
gene id: 230844:LOC102908338
uniprot id: A0A6J0CXE2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor T2R family.
messages: Membrane

230844:Scube1
gene id: 230844:Scube1
uniprot id: A0A6I9LJH8
uniprot id: A0A6I9LPE5
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

230844:Stk32b
gene id: 230844:Stk32b
uniprot id: A0A6I9M115
names: Similarity
messages: Belongs to the protein kinase superfamily.

230844:Mab21l3
gene id: 230844:Mab21l3
uniprot id: A0A6J0CRU9
names: Similarity
messages: Belongs to the mab-21 family.

230844:Mrpl44
gene id: 230844:Mrpl44
uniprot id: A0A6I9KWA7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ribonuclease III family. Mitochondrion-specific ribosomal protein mL44 subfamily.
messages: Mitochondrion

230844:LOC102921672
gene id: 230844:LOC102921672
uniprot id: A0A6I9M950
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Adora1
gene id: 230844:Adora1
uniprot id: A0A6J0DND8
uniprot id: A0A6J0DNV6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for adenosine. The activity of this receptor is mediated by G proteins which inhibit adenylyl cyclase.

230844:Kcnmb2
gene id: 230844:Kcnmb2
uniprot id: A0A6I9L0V2
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KCNMB (TC 8.A.14.1) family.
messages: Interacts with KCNMA1 tetramer. There are probably 4 molecules of KCMNB per KCNMA1 tetramer.
messages: Membrane
messages: N-glycosylated.
messages: Regulatory subunit of the calcium activated potassium KCNMA1 (maxiK) channel. Modulates the calcium sensitivity and gating kinetics of KCNMA1, thereby contributing to KCNMA1 channel diversity.

230844:Capn1
gene id: 230844:Capn1
uniprot id: A0A6I9LQH3
names: Similarity
messages: Belongs to the peptidase C2 family.

230844:Psph
gene id: 230844:Psph
uniprot id: A0A6I9KV31
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

230844:LOC102917876
gene id: 230844:LOC102917876
uniprot id: A0A6I9LZG5
uniprot id: A0A6J0E0D7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Hdac8
gene id: 230844:Hdac8
uniprot id: A0A6I9ML56
uniprot id: A0A6J0CTK9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone deacetylase family. HD Type 1 subfamily.
messages: Belongs to the histone deacetylase family. HD type 1 subfamily.
messages: Nucleus

230844:Lipg
gene id: 230844:Lipg
uniprot id: A0A6I9L6C4
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AB hydrolase superfamily. Lipase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

230844:LOC102909685
gene id: 230844:LOC102909685
uniprot id: A0A6I9ML47
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor T2R family.
messages: Membrane

230844:Dtnb
gene id: 230844:Dtnb
uniprot id: A0A6J0DHV9
uniprot id: A0A6J0DHW3
uniprot id: A0A6J0DHW7
uniprot id: A0A6J0DKB4
uniprot id: A0A6J0DKB9
uniprot id: A0A6J0DKE7
uniprot id: A0A6J0DKQ4
uniprot id: A0A6J0DKR6
uniprot id: A0A6J0DRE1
uniprot id: A0A6J0DRE6
uniprot id: A0A6J0DRF1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dystrophin family. Dystrobrevin subfamily.
messages: Cytoplasm

230844:Magi1
gene id: 230844:Magi1
uniprot id: A0A6I9KWU9
uniprot id: A0A6I9KX16
uniprot id: A0A6I9KX19
uniprot id: A0A6I9L3L8
uniprot id: A0A6I9L3W3
uniprot id: A0A6I9L756
uniprot id: A0A6J0CNM4
uniprot id: A0A6J0CNT5
uniprot id: A0A6J0CQ07
uniprot id: A0A6J0CQ48
uniprot id: A0A6J0CQP8
uniprot id: A0A6J0CQQ3
uniprot id: A0A6J0CQQ8
uniprot id: A0A6J0CQS8
uniprot id: A0A6J0CSR7
uniprot id: A0A6J0CSU4
uniprot id: A0A6J0CSY3
names: Subcellular Location Annotation
messages: Membrane

230844:Strip2
gene id: 230844:Strip2
uniprot id: A0A6I9LAJ2
names: Similarity
messages: Belongs to the STRIP family.

230844:Gabrd
gene id: 230844:Gabrd
uniprot id: A0A6I9MDZ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

230844:LOC102928024
gene id: 230844:LOC102928024
uniprot id: A0A6I9MQL8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Chst8
gene id: 230844:Chst8
uniprot id: A0A6J0DUE3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 2 family.
messages: Golgi apparatus membrane
messages: Membrane

230844:Pgam2
gene id: 230844:Pgam2
uniprot id: A0A6I9L827
names: Similarity
messages: Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.

230844:Aga
gene id: 230844:Aga
uniprot id: A0A6I9KTN1
names: Similarity
messages: Belongs to the Ntn-hydrolase family.

230844:Tm4sf19
gene id: 230844:Tm4sf19
uniprot id: A0A6I9LBL6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L6 tetraspanin family.
messages: Membrane

230844:Mif
gene id: 230844:Mif
uniprot id: A0A6I9M8E1
names: Similarity
messages: Belongs to the MIF family.

230844:Mpp3
gene id: 230844:Mpp3
uniprot id: A0A6I9L2M9
names: Similarity
messages: Belongs to the MAGUK family.

230844:LOC102913301
gene id: 230844:LOC102913301
uniprot id: A0A6I9LKN5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome c oxidase VIII family.
messages: Component of the cytochrome c oxidase (complex IV, CIV), a multisubunit enzyme composed of 14 subunits. The complex is composed of a catalytic core of 3 subunits MT-CO1, MT-CO2 and MT-CO3, encoded in the mitochondrial DNA, and 11 supernumerary subunits COX4I, COX5A, COX5B, COX6A, COX6B, COX6C, COX7A, COX7B, COX7C, COX8 and NDUFA4, which are encoded in the nuclear genome. The complex exists as a monomer or a dimer and forms supercomplexes (SCs) in the inner mitochondrial membrane with NADH-ubiquinone oxidoreductase (complex I, CI) and ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII), resulting in different assemblies (supercomplex SCI(1)III(2)IV(1) and megacomplex MCI(2)III(2)IV(2)).
messages: Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)). The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
messages: Membrane
messages: Mitochondrion inner membrane

230844:Calcr
gene id: 230844:Calcr
uniprot id: A0A6J0EB64
uniprot id: A0A6J0ED67
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 2 family.
messages: Cell membrane
messages: Interacts with GPRASP2.
messages: Membrane

230844:Pitpnm3
gene id: 230844:Pitpnm3
uniprot id: A0A6J0CDK6
uniprot id: A0A6J0CFN7
uniprot id: A0A6J0CGA4
uniprot id: A0A6J0CHM4
uniprot id: A0A6J0CHM8
names: Similarity
messages: Belongs to the PtdIns transfer protein family. PI transfer class IIA subfamily.

230844:Ldb3
gene id: 230844:Ldb3
uniprot id: A0A6I9L520
uniprot id: A0A6I9LCG1
uniprot id: A0A6I9LGB8
uniprot id: A0A6J0D7L3
names: Subcellular Location Annotation
messages: Z line

230844:LOC102906844
gene id: 230844:LOC102906844
uniprot id: A0A6I9LX03
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Tbpl1
gene id: 230844:Tbpl1
uniprot id: A0A6I9LJ32
names: Similarity
names: Subunit
messages: Belongs to the TBP family.
messages: Binds TFIIA and TFIIB.

230844:LOC102911065
gene id: 230844:LOC102911065
uniprot id: A0A6I9MG21
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Kcnh1
gene id: 230844:Kcnh1
uniprot id: A0A6I9M2C4
uniprot id: A0A6I9M668
names: Subcellular Location Annotation
messages: Membrane

230844:Tmem86b
gene id: 230844:Tmem86b
uniprot id: A0A6I9MD55
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM86 family.
messages: Membrane

230844:Gdf9
gene id: 230844:Gdf9
uniprot id: A0A6I9MIQ4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TGF-beta family.
messages: Homodimer or heterodimer (Potential). But, in contrast to other members of this family, cannot be disulfide-linked.
messages: Secreted

230844:Serinc3
gene id: 230844:Serinc3
uniprot id: A0A6I9L3J2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TDE1 family.
messages: Membrane

230844:Timm9
gene id: 230844:Timm9
uniprot id: A0A6I9MB10
uniprot id: A0A6J0E7Z8
uniprot id: A0A6J0E9R6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the small Tim family.
messages: Heterohexamer.
messages: Mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space.
messages: Mitochondrion inner membrane
messages: The twin CX3C motif contains 4 conserved Cys residues that form 2 disulfide bonds in the mitochondrial intermembrane space.

230844:LOC102914779
gene id: 230844:LOC102914779
uniprot id: A0A6I9LZ74
names: Similarity
messages: Belongs to the aldo/keto reductase family.

230844:Slc25a44
gene id: 230844:Slc25a44
uniprot id: A0A6I9L4F4
uniprot id: A0A6J0D738
uniprot id: A0A6J0D7K8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

230844:Tenm2
gene id: 230844:Tenm2
uniprot id: A0A6I9KV34
uniprot id: A0A6I9KVI7
uniprot id: A0A6I9L211
uniprot id: A0A6J0DXB5
uniprot id: A0A6J0DXC6
uniprot id: A0A6J0DXD3
uniprot id: A0A6J0E1M3
uniprot id: A0A6J0E5H0
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tenascin family. Teneurin subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

230844:LOC102912552
gene id: 230844:LOC102912552
uniprot id: A0A6I9ME38
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

230844:Rab18
gene id: 230844:Rab18
uniprot id: A0A6I9LA58
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Cell membrane
messages: Lipid droplet

230844:Gosr2
gene id: 230844:Gosr2
uniprot id: A0A6I9KZE3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GOSR2 family.
messages: Involved in transport of proteins from the cis/medial-Golgi to the trans-Golgi network.
messages: Membrane

230844:LOC102928841
gene id: 230844:LOC102928841
uniprot id: A0A6J0DXW2
names: Similarity
names: Subunit
messages: Belongs to the histone H3 family.
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

230844:Rnf141
gene id: 230844:Rnf141
uniprot id: A0A6I9LGV8
names: Function
messages: May be involved in spermatogenesis.

230844:LOC102910408
gene id: 230844:LOC102910408
uniprot id: A0A6I9L4C3
names: Similarity
messages: Belongs to the FAM136 family.

230844:LOC102919749
gene id: 230844:LOC102919749
uniprot id: A0A6J0EDQ6
names: Similarity
messages: Belongs to the Tdpoz family.

230844:LOC102905992
gene id: 230844:LOC102905992
uniprot id: A0A6I9LHU6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:LOC102922536
gene id: 230844:LOC102922536
uniprot id: A0A6I9MJ38
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:LOC102928711
gene id: 230844:LOC102928711
uniprot id: A0A6I9MGI2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Tnfrsf25
gene id: 230844:Tnfrsf25
uniprot id: A0A6I9MGS1
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

230844:LOC102916115
gene id: 230844:LOC102916115
uniprot id: A0A6I9M070
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PMG family.
messages: In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins.
messages: Interacts with hair keratins.

230844:Mdga1
gene id: 230844:Mdga1
uniprot id: A0A6I9LVV8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

230844:Pdp2
gene id: 230844:Pdp2
uniprot id: A0A6I9LGN7
names: Similarity
messages: Belongs to the PP2C family.

230844:Prmt7
gene id: 230844:Prmt7
uniprot id: A0A6J0E115
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Arginine methyltransferase that can both catalyze the formation of omega-N monomethylarginine (MMA) and symmetrical dimethylarginine (sDMA), with a preference for the formation of MMA. Specifically mediates the symmetrical dimethylation of arginine residues in the small nuclear ribonucleoproteins Sm D1 (SNRPD1) and Sm D3 (SNRPD3); such methylation being required for the assembly and biogenesis of snRNP core particles. Specifically mediates the symmetric dimethylation of histone H4 'Arg-3' to form H4R3me2s. Plays a role in gene imprinting by being recruited by CTCFL at the H19 imprinted control region (ICR) and methylating histone H4 to form H4R3me2s, possibly leading to recruit DNA methyltransferases at these sites. May also play a role in embryonic stem cell (ESC) pluripotency. Also able to mediate the arginine methylation of histone H2A and myelin basic protein (MBP) in vitro; the relevance of such results is however unclear in vivo.
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. PRMT7 subfamily.
messages: Nucleus
messages: cytosol

230844:LOC102915298
gene id: 230844:LOC102915298
uniprot id: A0A6I9LXF2
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane

230844:Slc30a9
gene id: 230844:Slc30a9
uniprot id: A0A6I9L889
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily.
messages: Endoplasmic reticulum
messages: Membrane
messages: Mitochondrion membrane
messages: Nucleus

230844:Hoxc9
gene id: 230844:Hoxc9
uniprot id: A0A6J0DLY2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Abd-B homeobox family.
messages: Nucleus
messages: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

230844:LOC102919295
gene id: 230844:LOC102919295
uniprot id: A0A6J0DRE0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UDP-glycosyltransferase family.
messages: Membrane

230844:Gna15
gene id: 230844:Gna15
uniprot id: A0A6I9LJG6
names: Similarity
messages: Belongs to the G-alpha family. G(q) subfamily.

230844:LOC102915264
gene id: 230844:LOC102915264
uniprot id: A0A6I9MNG0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:LOC102927408
gene id: 230844:LOC102927408
uniprot id: A0A6J0CWY7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:LOC102909161
gene id: 230844:LOC102909161
uniprot id: A0A6J0CRX5
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M10A family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Can bind about 5 Ca(2+) ions per subunit.

230844:Dusp3
gene id: 230844:Dusp3
uniprot id: A0A6I9KT56
names: Function
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.
messages: Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate.

230844:Sema3b
gene id: 230844:Sema3b
uniprot id: A0A6J0DCI7
names: Caution
names: Similarity
messages: Belongs to the semaphorin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

230844:Znf287
gene id: 230844:Znf287
uniprot id: A0A6J0CY69
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the krueppel C2H2-type zinc-finger protein family.
messages: Nucleus

230844:LOC102915094
gene id: 230844:LOC102915094
uniprot id: A0A6I9M4X8
names: Similarity
messages: Belongs to the aldo/keto reductase family.

230844:Lamtor3
gene id: 230844:Lamtor3
uniprot id: A0A6J0CZA9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LAMTOR3 family.
messages: Endosome membrane
messages: Late endosome membrane

230844:Tmem131l
gene id: 230844:Tmem131l
uniprot id: A0A6I9LMI7
uniprot id: A0A6I9LVG0
uniprot id: A0A6J0E1X6
names: Similarity
messages: Belongs to the TMEM131 family.

230844:Slc30a1
gene id: 230844:Slc30a1
uniprot id: A0A6I9LQ80
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily.
messages: Membrane

230844:Mpv17l
gene id: 230844:Mpv17l
uniprot id: A0A6I9LXC8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peroxisomal membrane protein PXMP2/4 family.
messages: Membrane

230844:Usp51
gene id: 230844:Usp51
uniprot id: A0A6I9M9P7
names: Function
names: Similarity
messages: Belongs to the peptidase C19 family.
messages: Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes.

230844:Eno3
gene id: 230844:Eno3
uniprot id: A0A6I9MC64
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Cytoplasm

230844:Anxa1
gene id: 230844:Anxa1
uniprot id: A0A6I9LMS3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Basolateral cell membrane
messages: Belongs to the annexin family.
messages: Cell membrane
messages: Cytoplasmic vesicle membrane
messages: Early endosome
messages: Endosome membrane
messages: Functions at least in part by activating the formyl peptide receptors and downstream signaling cascades. Promotes chemotaxis of granulocytes and monocytes via activation of the formyl peptide receptors. Promotes rearrangement of the actin cytoskeleton, cell polarization and cell migration. Promotes resolution of inflammation and wound healing. Acts via neutrophil N-formyl peptide receptors to enhance the release of CXCL2.
messages: Lateral cell membrane
messages: Membrane
messages: Nucleus
messages: The full-length protein can bind eight Ca(2+) ions via the annexin repeats. Calcium binding causes a major conformation change that modifies dimer contacts and leads to surface exposure of the N-terminal phosphorylation sites; in the absence of Ca(2+), these sites are buried in the interior of the protein core. The N-terminal region becomes disordered in response to calcium-binding.
messages: cilium
messages: extracellular exosome
messages: extracellular space
messages: phagocytic cup
messages: secretory vesicle lumen

230844:Slc16a1
gene id: 230844:Slc16a1
uniprot id: A0A6I9MIG5
names: Subcellular Location Annotation
messages: Basolateral cell membrane
messages: Lateral cell membrane
messages: Membrane

230844:Grm3
gene id: 230844:Grm3
uniprot id: A0A6J0E6Z2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 3 family.
messages: Cell membrane
messages: G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. Signaling inhibits adenylate cyclase activity.
messages: Interacts with TAMALIN.
messages: Membrane

230844:Pdgfd
gene id: 230844:Pdgfd
uniprot id: A0A6I9LRJ6
uniprot id: A0A6I9LX45
uniprot id: A0A6J0DPH0
uniprot id: A0A6J0DY04
names: Caution
names: Similarity
messages: Belongs to the PDGF/VEGF growth factor family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

230844:Cavin1
gene id: 230844:Cavin1
uniprot id: A0A6I9LYR7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CAVIN family.
messages: caveola

230844:Phkg2
gene id: 230844:Phkg2
uniprot id: A0A6I9L5T5
names: Similarity
names: Subunit
messages: Belongs to the protein kinase superfamily.
messages: Hexadecamer of 4 heterotetramers, each composed of alpha, beta, gamma, and delta subunits. Alpha (PHKA1 or PHKA2) and beta (PHKB) are regulatory subunits, gamma (PHKG1 or PHKG2) is the catalytic subunit, and delta is calmodulin.

230844:Syngr2
gene id: 230844:Syngr2
uniprot id: A0A6I9LZ03
uniprot id: A0A6J0E8L9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptogyrin family.
messages: Membrane

230844:LOC102908448
gene id: 230844:LOC102908448
uniprot id: A0A6J0D8A4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MDM2/MDM4 family.
messages: Cytoplasm
messages: nucleolus
messages: nucleoplasm

230844:Smarcd3
gene id: 230844:Smarcd3
uniprot id: A0A6I9M1R6
uniprot id: A0A6I9MII4
uniprot id: A0A6J0CLA3
uniprot id: A0A6J0CM60
uniprot id: A0A6J0CPU5
names: Similarity
messages: Belongs to the SMARCD family.

230844:Myo6
gene id: 230844:Myo6
uniprot id: A0A6J0DH11
uniprot id: A0A6J0DM63
uniprot id: A0A6J0DM68
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
messages: clathrin-coated pit
messages: clathrin-coated vesicle
messages: filopodium
messages: microvillus
messages: ruffle membrane
messages: trans-Golgi network membrane

230844:Gpr31
gene id: 230844:Gpr31
uniprot id: A0A6I9LAW7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

230844:LOC102928992
gene id: 230844:LOC102928992
uniprot id: A0A6I9ME45
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Selenom
gene id: 230844:Selenom
uniprot id: A0A6I9KXR9
names: Similarity
messages: Belongs to the selenoprotein M/F family.

230844:Btg1
gene id: 230844:Btg1
uniprot id: A0A6I9MD08
names: Similarity
messages: Belongs to the BTG family.

230844:LOC102914423
gene id: 230844:LOC102914423
uniprot id: A0A6J0DAQ4
names: Similarity
messages: Belongs to the GAB family.

230844:Arg2
gene id: 230844:Arg2
uniprot id: A0A6I9L538
names: Cofactor
names: Similarity
messages: Belongs to the arginase family.
messages: Binds 2 manganese ions per subunit.

230844:Asb18
gene id: 230844:Asb18
uniprot id: A0A6I9LV36
uniprot id: A0A6I9M3B1
names: Similarity
messages: Belongs to the ankyrin SOCS box (ASB) family.

230844:Ripply2
gene id: 230844:Ripply2
uniprot id: A0A6I9LSI1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ripply family.
messages: Nucleus

230844:Sorcs2
gene id: 230844:Sorcs2
uniprot id: A0A6I9LKM1
uniprot id: A0A6J0DUA7
names: Similarity
messages: Belongs to the VPS10-related sortilin family. SORCS subfamily.

230844:LOC102923456
gene id: 230844:LOC102923456
uniprot id: A0A6J0CS18
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Chromosome
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers.
messages: Variant histone H2A which replaces conventional H2A in a subset of nucleosomes.

230844:LOC102922733
gene id: 230844:LOC102922733
uniprot id: A0A6J0DAC1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 2-5A synthase family.
messages: Cytoplasm

230844:Ap1m1
gene id: 230844:Ap1m1
uniprot id: A0A6I9M3Z4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adaptor complexes medium subunit family.
messages: Golgi apparatus
messages: Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the trans-Golgi network (TGN) and endosomes. The AP complexes mediate the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules.
messages: clathrin-coated vesicle membrane

230844:Tap2
gene id: 230844:Tap2
uniprot id: A0A6I9MDS8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCB family. MHC peptide exporter (TC 3.A.1.209) subfamily.
messages: Membrane

230844:Pla1a
gene id: 230844:Pla1a
uniprot id: A0A6I9LAI6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AB hydrolase superfamily. Lipase family.
messages: Secreted

230844:Arrdc4
gene id: 230844:Arrdc4
uniprot id: A0A6I9LTS6
names: Similarity
messages: Belongs to the arrestin family.

230844:Syt14
gene id: 230844:Syt14
uniprot id: A0A6I9LTZ3
uniprot id: A0A6I9M2B9
uniprot id: A0A6J0E1G8
uniprot id: A0A6J0E6G2
uniprot id: A0A6J0E953
names: Similarity
messages: Belongs to the synaptotagmin family.

230844:Flnc
gene id: 230844:Flnc
uniprot id: A0A6I9LIT5
names: Similarity
messages: Belongs to the filamin family.

230844:LOC102907577
gene id: 230844:LOC102907577
uniprot id: A0A6I9LSX5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Pik3cb
gene id: 230844:Pik3cb
uniprot id: A0A6I9L1Z1
names: Similarity
messages: Belongs to the PI3/PI4-kinase family. Type III PI4K subfamily.

230844:Tube1
gene id: 230844:Tube1
uniprot id: A0A6I9LI92
names: Similarity
messages: Belongs to the tubulin family.

230844:LOC102904332
gene id: 230844:LOC102904332
uniprot id: A0A6I9MLI8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor T2R family.
messages: Membrane

230844:Nmur2
gene id: 230844:Nmur2
uniprot id: A0A6I9LUP7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for the neuromedin-U and neuromedin-S neuropeptides.

230844:Mnat1
gene id: 230844:Mnat1
uniprot id: A0A6I9MEM1
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Associates with CDK7 and cyclin H.
messages: Nucleus
messages: Stabilizes the cyclin H-CDK7 complex to form a functional CDK-activating kinase (CAK) enzymatic complex.

230844:LOC102922844
gene id: 230844:LOC102922844
uniprot id: A0A6I9MGW1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Slc39a13
gene id: 230844:Slc39a13
uniprot id: A0A6I9LSR1
uniprot id: A0A6I9LY72
uniprot id: A0A6J0DR12
names: Subcellular Location Annotation
messages: Membrane

230844:Polr2h
gene id: 230844:Polr2h
uniprot id: A0A6I9LZX7
names: Similarity
messages: Belongs to the eukaryotic RPB8 RNA polymerase subunit family.

230844:Csnk2b
gene id: 230844:Csnk2b
uniprot id: A0A6I9M2V2
uniprot id: A0A6J0CRK1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the casein kinase 2 subunit beta family.
messages: Regulatory subunit of casein kinase II/CK2. As part of the kinase complex regulates the basal catalytic activity of the alpha subunit a constitutively active serine/threonine-protein kinase that phosphorylates a large number of substrates containing acidic residues C-terminal to the phosphorylated serine or threonine. Participates in Wnt signaling.
messages: Tetramer of two alpha and two beta subunits.

230844:Ier5
gene id: 230844:Ier5
uniprot id: A0A6I9LW23
names: Similarity
messages: Belongs to the IER family.

230844:Fam20a
gene id: 230844:Fam20a
uniprot id: A0A6I9KZ63
names: Similarity
messages: Belongs to the FAM20 family.

230844:LOC102919971
gene id: 230844:LOC102919971
uniprot id: A0A6I9MAQ4
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily.

230844:Sptb
gene id: 230844:Sptb
uniprot id: A0A6I9L8F6
names: Similarity
messages: Belongs to the spectrin family.

230844:Idh3g
gene id: 230844:Idh3g
uniprot id: A0A6I9M497
uniprot id: A0A6J0CE86
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.
messages: Heterooligomer of subunits alpha (IDH3A), beta (IDH3B), and gamma (IDH3G) in the apparent ratio of 2:1:1. The heterodimer containing one IDH3A and one IDH3B subunit and the heterodimer containing one IDH3A and one IDH3G subunit assemble into a heterotetramer (which contains two subunits of IDH3A, one of IDH3B and one of IDH3G) and further into the heterooctamer.
messages: Mitochondrion

230844:Brcc3
gene id: 230844:Brcc3
uniprot id: A0A6I9MNL6
uniprot id: A0A6J0CX43
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase M67A family. BRCC36 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Component of the ARISC complex, at least composed of UIMC1/RAP80, ABRAXAS1, BRCC3/BRCC36, BABAM2 and BABAM1/NBA1. Component of the BRCA1-A complex, at least composed of BRCA1, BARD1, UIMC1/RAP80, ABRAXAS1, BRCC3/BRCC36, BABAM2 and BABAM1/NBA1. In the BRCA1-A complex, interacts directly with ABRAXAS1 and BABAM2. Component of the BRISC complex, at least composed of ABRAXAS2, BRCC3/BRCC36, BABAM2 and BABAM1/NBA1. Identified in a complex with SHMT2 and the other subunits of the BRISC complex. In the BRISC complex, interacts directly with ABRAXAS2. Identified in a complex with ABRAXAS2 and NUMA1. The BRISC complex interacts with the CSN complex. Component of the BRCA1/BRCA2 containing complex (BRCC), which also contains BRCA1, BRCA2, BARD1, BABAM2 and RAD51. BRCC is a ubiquitin E3 ligase complex that enhances cellular survival following DNA damage. Interacts with BRCA1. Binds polyubiquitin. Interacts with PWWP2B. Interacts with HDAC1; this interaction is enhanced in the presence of PWWP2B.
messages: Cytoplasm
messages: Metalloprotease that specifically cleaves 'Lys-63'-linked polyubiquitin chains. Component of the BRCA1-A complex, a complex that specifically recognizes 'Lys-63'-linked ubiquitinated histones H2A and H2AX at DNA lesions sites, leading to target the brca1-bard1 heterodimer to sites of DNA damage at double-strand breaks (DSBs). Catalytic subunit of the BRISC complex, a multiprotein complex that specifically cleaves 'Lys-63'-linked ubiquitin in various substrates. Mediates the specific 'Lys-63'-specific deubiquitination associated with the COP9 signalosome complex (CSN), via the interaction of the BRISC complex with the CSN complex. The BRISC complex is required for normal mitotic spindle assembly and microtubule attachment to kinetochores via its role in deubiquitinating NUMA1.
messages: Nucleus
messages: spindle pole

230844:Efna1
gene id: 230844:Efna1
uniprot id: A0A6I9L3G7
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ephrin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

230844:Slc45a3
gene id: 230844:Slc45a3
uniprot id: A0A6I9LVI3
names: Subcellular Location Annotation
messages: Membrane

230844:Dmrt2
gene id: 230844:Dmrt2
uniprot id: A0A6J0D8G5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DMRT family.
messages: Nucleus

230844:Slc22a3
gene id: 230844:Slc22a3
uniprot id: A0A6I9L6H4
names: Similarity
messages: Belongs to the major facilitator (TC 2.A.1) superfamily. Organic cation transporter (TC 2.A.1.19) family.

230844:Mcm7
gene id: 230844:Mcm7
uniprot id: A0A6I9KU96
uniprot id: A0A6I9L0Z7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acts as component of the MCM2-7 complex (MCM complex) which is the replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity.
messages: Belongs to the MCM family.
messages: Chromosome
messages: Nucleus

230844:Xkr9
gene id: 230844:Xkr9
uniprot id: A0A6J0D275
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the XK family.
messages: Membrane

230844:Arvcf
gene id: 230844:Arvcf
uniprot id: A0A6J0CJN1
uniprot id: A0A6J0CM13
uniprot id: A0A6J0CP49
names: Similarity
messages: Belongs to the beta-catenin family.

230844:Polr3b
gene id: 230844:Polr3b
uniprot id: A0A6I9LYN8
names: Function
names: Similarity
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.

230844:Vamp8
gene id: 230844:Vamp8
uniprot id: A0A6I9MBP8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptobrevin family.
messages: Membrane

230844:Immt
gene id: 230844:Immt
uniprot id: A0A6I9LV95
uniprot id: A0A6I9M689
uniprot id: A0A6I9M7G0
uniprot id: A0A6I9MBI4
uniprot id: A0A6J0E8T2
uniprot id: A0A6J0E8T7
uniprot id: A0A6J0EAJ2
uniprot id: A0A6J0ECK9
uniprot id: A0A6J0EEP5
uniprot id: A0A6J0EGB7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MICOS complex subunit Mic60 family.
messages: Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane.
messages: Component of the mitochondrial contact site and cristae organizing system (MICOS) complex.
messages: Mitochondrion inner membrane

230844:Xirp1
gene id: 230844:Xirp1
uniprot id: A0A6I9MFZ1
names: Domain
names: Function
names: Similarity
messages: Belongs to the Xin family.
messages: Protects actin filaments from depolymerization.
messages: Xin repeats bind F-actin.

230844:LOC102909236
gene id: 230844:LOC102909236
uniprot id: A0A6I9M4T7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Slc30a10
gene id: 230844:Slc30a10
uniprot id: A0A6I9L2H3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily.
messages: Membrane

230844:Homer1
gene id: 230844:Homer1
uniprot id: A0A6J0DLT6
uniprot id: A0A6J0DSL2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Homer family.
messages: Cytoplasm
messages: Postsynaptic density
messages: Synapse

230844:Strip1
gene id: 230844:Strip1
uniprot id: A0A6I9LHZ5
uniprot id: A0A6J0DF92
names: Similarity
messages: Belongs to the STRIP family.

230844:Nme4
gene id: 230844:Nme4
uniprot id: A0A6I9LGM0
names: Similarity
messages: Belongs to the NDK family.

230844:LOC102907154
gene id: 230844:LOC102907154
uniprot id: A0A6I9LY92
names: Similarity
messages: Belongs to the cytochrome P450 family.

230844:Antxr2
gene id: 230844:Antxr2
uniprot id: A0A6I9L1T4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATR family.
messages: Membrane

230844:Bhlhb9
gene id: 230844:Bhlhb9
uniprot id: A0A6J0CVG2
names: Similarity
messages: Belongs to the GPRASP family.

230844:LOC102916319
gene id: 230844:LOC102916319
uniprot id: A0A6I9LPT4
uniprot id: A0A6J0DHS9
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-3 subunit C family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is composed of 13 subunits: EIF3A, EIF3B, EIF3C, EIF3D, EIF3E, EIF3F, EIF3G, EIF3H, EIF3I, EIF3J, EIF3K, EIF3L and EIF3M. The eIF-3 complex appears to include 3 stable modules: module A is composed of EIF3A, EIF3B, EIF3G and EIF3I; module B is composed of EIF3F, EIF3H, and EIF3M; and module C is composed of EIF3C, EIF3D, EIF3E, EIF3K and EIF3L. EIF3C of module C binds EIF3B of module A and EIF3H of module B, thereby linking the three modules. EIF3J is a labile subunit that binds to the eIF-3 complex via EIF3B. The eIF-3 complex interacts with RPS6KB1 under conditions of nutrient depletion. Mitogenic stimulation leads to binding and activation of a complex composed of MTOR and RPTOR, leading to phosphorylation and release of RPS6KB1 and binding of EIF4B to eIF-3.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation, including cell cycling, differentiation and apoptosis, and uses different modes of RNA stem-loop binding to exert either translational activation or repression.
messages: Cytoplasm
messages: Phosphorylated. Phosphorylation is enhanced upon serum stimulation.

230844:LOC102906957
gene id: 230844:LOC102906957
uniprot id: A0A6I9LXR7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:LOC102915006
gene id: 230844:LOC102915006
uniprot id: A0A6I9KWK5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for angiotensin II, a vasoconstricting peptide, which acts as a key regulator of blood pressure and sodium retention by the kidney. The activated receptor in turn couples to G-alpha proteins G(q) and thus activates phospholipase C and increases the cytosolic Ca(2+) concentrations, which in turn triggers cellular responses such as stimulation of protein kinase C.

230844:LOC102911691
gene id: 230844:LOC102911691
uniprot id: A0A6I9MPE4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thymosin beta family.
messages: cytoskeleton

230844:Ranbp17
gene id: 230844:Ranbp17
uniprot id: A0A6I9LGR0
uniprot id: A0A6J0DDK5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exportin family.
messages: Cytoplasm
messages: Nucleus

230844:LOC102905141
gene id: 230844:LOC102905141
uniprot id: A0A6I9MBZ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Kpna6
gene id: 230844:Kpna6
uniprot id: A0A6I9M8L4
uniprot id: A0A6J0CKI2
names: Function
names: Similarity
messages: Belongs to the importin alpha family.
messages: Functions in nuclear protein import.

230844:Hhat
gene id: 230844:Hhat
uniprot id: A0A6I9LQ76
names: Subcellular Location Annotation
messages: Membrane

230844:Itgav
gene id: 230844:Itgav
uniprot id: A0A6I9MKR9
uniprot id: A0A6I9MMK4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin alpha chain family.
messages: Membrane

230844:Ffar4
gene id: 230844:Ffar4
uniprot id: A0A6I9LCD2
names: Subcellular Location Annotation
messages: Membrane

230844:Eri1
gene id: 230844:Eri1
uniprot id: A0A6I9L6M7
names: Subcellular Location Annotation
messages: Cytoplasm

230844:LOC102908178
gene id: 230844:LOC102908178
uniprot id: A0A6I9M7I1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:LOC102907544
gene id: 230844:LOC102907544
uniprot id: A0A6I9MQQ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Pou5f1
gene id: 230844:Pou5f1
uniprot id: A0A6I9MI99
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the POU transcription factor family.
messages: Nucleus

230844:Fpr2
gene id: 230844:Fpr2
uniprot id: A0A6I9MF68
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Belongs to the chemokine-like receptor (CMKLR) family.
messages: Membrane

230844:Kif21b
gene id: 230844:Kif21b
uniprot id: A0A6I9LGM1
uniprot id: A0A6J0DKP1
uniprot id: A0A6J0DKP8
uniprot id: A0A6J0DMY4
uniprot id: A0A6J0DN91
uniprot id: A0A6J0DNQ6
uniprot id: A0A6J0DUH9
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

230844:Mon1a
gene id: 230844:Mon1a
uniprot id: A0A6I9L726
names: Function
names: Similarity
messages: Belongs to the MON1/SAND family.
messages: Plays an important role in membrane trafficking through the secretory apparatus.

230844:Hoxa10
gene id: 230844:Hoxa10
uniprot id: A0A6I9LEF1
uniprot id: A0A6I9LU82
uniprot id: A0A6J0DN48
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Abd-B homeobox family.
messages: Nucleus

230844:Iars1
gene id: 230844:Iars1
uniprot id: A0A6I9LXN3
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

230844:Gnpda2
gene id: 230844:Gnpda2
uniprot id: A0A6I9LJE4
uniprot id: A0A6J0DFR8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family.
messages: Cytoplasm
messages: Homohexamer.

230844:Cct4
gene id: 230844:Cct4
uniprot id: A0A6I9L0V4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TCP-1 chaperonin family.
messages: Cytoplasm

230844:Mettl6
gene id: 230844:Mettl6
uniprot id: A0A6I9LEU7
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily. METL family.
messages: S-adenosyl-L-methionine-dependent methyltransferase.

230844:Ezh1
gene id: 230844:Ezh1
uniprot id: A0A6J0CGV2
names: Subcellular Location Annotation
messages: Nucleus

230844:LOC102919348
gene id: 230844:LOC102919348
uniprot id: A0A6I9LSQ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NIP3 family.
messages: Membrane

230844:Rnf168
gene id: 230844:Rnf168
uniprot id: A0A6I9L808
names: Caution
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: According to a well-established model, RNF168 cannot initiate H2A 'Lys-63'-linked ubiquitination and is recruited following RNF8-dependent histone ubiquitination to amplify H2A 'Lys-63'-linked ubiquitination. However, other data suggest that RNF168 is the priming ubiquitin ligase by mediating monoubiquitination of 'Lys-13' and 'Lys-15' of nucleosomal histone H2A (H2AK13Ub and H2AK15Ub respectively). These data suggest that RNF168 might be recruited to DSBs sites in a RNF8-dependent manner by binding to non-histone proteins ubiquitinated via 'Lys-63'-linked and initiates monoubiquitination of H2A, which is then amplified by RNF8. Additional evidences are however required to confirm these data.
messages: Belongs to the RNF168 family.
messages: E3 ubiquitin-protein ligase required for accumulation of repair proteins to sites of DNA damage. Acts with UBE2N/UBC13 to amplify the RNF8-dependent histone ubiquitination. Recruited to sites of DNA damage at double-strand breaks (DSBs) by binding to ubiquitinated histone H2A and H2AX and amplifies the RNF8-dependent H2A ubiquitination, promoting the formation of 'Lys-63'-linked ubiquitin conjugates. This leads to concentrate ubiquitinated histones H2A and H2AX at DNA lesions to the threshold required for recruitment of TP53BP1 and BRCA1. Also recruited at DNA interstrand cross-links (ICLs) sites and promotes accumulation of 'Lys-63'-linked ubiquitination of histones H2A and H2AX, leading to recruitment of FAAP20 and Fanconi anemia (FA) complex, followed by interstrand cross-link repair. H2A ubiquitination also mediates the ATM-dependent transcriptional silencing at regions flanking DSBs in cis, a mechanism to avoid collision between transcription and repair intermediates. Also involved in class switch recombination in immune system, via its role in regulation of DSBs repair. Following DNA damage, promotes the ubiquitination and degradation of JMJD2A/KDM4A in collaboration with RNF8, leading to unmask H4K20me2 mark and promote the recruitment of TP53BP1 at DNA damage sites. Not able to initiate 'Lys-63'-linked ubiquitination in vitro; possibly due to partial occlusion of the UBE2N/UBC13-binding region. Catalyzes monoubiquitination of 'Lys-13' and 'Lys-15' of nucleosomal histone H2A (H2AK13Ub and H2AK15Ub, respectively).
messages: Monomer. Interacts with UBE2N/UBC13.
messages: Nucleus
messages: Sumoylated with SUMO1 by PIAS4 in response to double-strand breaks (DSBs).
messages: The MIU motif (motif interacting with ubiquitin) mediates the interaction with both 'Lys-48'- and 'Lys-63'-linked ubiquitin chains. The UMI motif mediates interaction with ubiquitin with a preference for 'Lys-63'-linked ubiquitin. The specificity for different types of ubiquitin is mediated by juxtaposition of ubiquitin-binding motifs (MIU and UMI motifs) with LR motifs (LRMs).
messages: Ubiquitinated.

230844:LOC102904546
gene id: 230844:LOC102904546
uniprot id: A0A6I9MET5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

230844:Wdfy1
gene id: 230844:Wdfy1
uniprot id: A0A6I9L659
names: Subcellular Location Annotation
messages: Early endosome
messages: Endosome

230844:LOC102910568
gene id: 230844:LOC102910568
uniprot id: A0A6I9LKK7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome P450 family.
messages: Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.
messages: Endoplasmic reticulum membrane
messages: Microsome membrane

230844:LOC102902836
gene id: 230844:LOC102902836
uniprot id: A0A6I9M3T3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Nop53
gene id: 230844:Nop53
uniprot id: A0A6I9LVZ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NOP53 family.
messages: May play a role in ribosome biogenesis.
messages: nucleolus
messages: nucleoplasm

230844:Phkg1
gene id: 230844:Phkg1
uniprot id: A0A6I9L134
names: Similarity
names: Subunit
messages: Belongs to the protein kinase superfamily.
messages: Hexadecamer of 4 heterotetramers, each composed of alpha, beta, gamma, and delta subunits. Alpha (PHKA1 or PHKA2) and beta (PHKB) are regulatory subunits, gamma (PHKG1 or PHKG2) is the catalytic subunit, and delta is calmodulin.

230844:Sec23b
gene id: 230844:Sec23b
uniprot id: A0A6I9LYD7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEC23/SEC24 family. SEC23 subfamily.
messages: COPII-coated vesicle membrane
messages: Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: cytosol

230844:C19H18orf21
gene id: 230844:C19H18orf21
uniprot id: A0A6I9LBZ0
uniprot id: A0A6I9LJ56
names: Similarity
messages: Belongs to the UPF0711 family.

230844:Map4
gene id: 230844:Map4
uniprot id: A0A6J0DVI7
uniprot id: A0A6J0E3J6
names: Subcellular Location Annotation
messages: cytoskeleton

230844:Gpr18
gene id: 230844:Gpr18
uniprot id: A0A6J0DIJ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

230844:Ecsit
gene id: 230844:Ecsit
uniprot id: A0A6I9LEP5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: As part of the MCIA complex, involved in the assembly of the mitochondrial complex I.
messages: Belongs to the ECSIT family.
messages: Cytoplasm
messages: Mitochondrion
messages: Nucleus

230844:Acad8
gene id: 230844:Acad8
uniprot id: A0A6I9LC98
uniprot id: A0A6I9LG24
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

230844:Pde6b
gene id: 230844:Pde6b
uniprot id: A0A6I9LWB8
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

230844:Ndufs6
gene id: 230844:Ndufs6
uniprot id: A0A6I9LYD8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFS6 subunit family.
messages: Mitochondrion inner membrane

230844:LOC102919363
gene id: 230844:LOC102919363
uniprot id: A0A6I9MKC2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Lpin2
gene id: 230844:Lpin2
uniprot id: A0A6I9KW97
uniprot id: A0A6I9L386
uniprot id: A0A6J0CJ37
names: Similarity
messages: Belongs to the lipin family.

230844:LOC102924641
gene id: 230844:LOC102924641
uniprot id: A0A6I9LFI2
names: Similarity
messages: Belongs to the intermediate filament family.

230844:Ins
gene id: 230844:Ins
uniprot id: A0A6I9LDU9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the insulin family.
messages: Heterodimer of a B chain and an A chain linked by two disulfide bonds.
messages: Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.
messages: Secreted

230844:LOC102904635
gene id: 230844:LOC102904635
uniprot id: A0A6J0CV75
names: Similarity
messages: Belongs to the fl(2)d family.

230844:LOC102921753
gene id: 230844:LOC102921753
uniprot id: A0A6I9LDS9
uniprot id: A0A6J0DPY8
names: Similarity
messages: Belongs to the ficolin lectin family.

230844:Gpr160
gene id: 230844:Gpr160
uniprot id: A0A6I9L0N1
names: Subcellular Location Annotation
messages: Membrane

230844:Prdx5
gene id: 230844:Prdx5
uniprot id: A0A6I9LQL0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peroxiredoxin family. Prx5 subfamily.
messages: Peroxisome matrix
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides and as sensor of hydrogen peroxide-mediated signaling events.

230844:Paics
gene id: 230844:Paics
uniprot id: A0A6J0CS68
names: Similarity
names: Subunit
messages: Homooctamer.
messages: In the C-terminal section; belongs to the AIR carboxylase family. Class II subfamily.
messages: In the N-terminal section; belongs to the SAICAR synthetase family.

230844:Arrdc1
gene id: 230844:Arrdc1
uniprot id: A0A6I9LDX9
uniprot id: A0A6J0DJA0
names: Similarity
messages: Belongs to the arrestin family.

230844:Kcnu1
gene id: 230844:Kcnu1
uniprot id: A0A6J0DP80
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the potassium channel family. Calcium-activated (TC 1.A.1.3) subfamily. KCa1.1/KCNMA1 sub-subfamily.
messages: Membrane

230844:Cwf19l2
gene id: 230844:Cwf19l2
uniprot id: A0A6I9MD95
names: Similarity
messages: Belongs to the CWF19 family.

230844:Topaz1
gene id: 230844:Topaz1
uniprot id: A0A6I9LHD7
names: Function
messages: Important for normal spermatogenesis and male fertility. Specifically required for progression to the post-meiotic stages of spermatocyte development. Seems to be necessary for normal expression levels of a number of testis-expressed gene transcripts, although its role in this process is unclear.

230844:Trmt44
gene id: 230844:Trmt44
uniprot id: A0A6I9LW09
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Adenosyl-L-methionine (AdoMet)-dependent tRNA (uracil-O(2)-)-methyltransferase.
messages: Belongs to the TRM44 family.
messages: Cytoplasm
messages: Probable adenosyl-L-methionine (AdoMet)-dependent tRNA (uracil-O(2)-)-methyltransferase.

230844:LOC102914326
gene id: 230844:LOC102914326
uniprot id: A0A6I9L7M9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Fgf1
gene id: 230844:Fgf1
uniprot id: A0A6J0D941
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heparin-binding growth factors family.
messages: Cytoplasm
messages: Nucleus
messages: Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integrins and FGFR1 are essential for FGF1 signaling.
messages: Secreted
messages: cell cortex
messages: cytosol

230844:Kri1
gene id: 230844:Kri1
uniprot id: A0A6I9LZD5
names: Similarity
messages: Belongs to the KRI1 family.

230844:Sufu
gene id: 230844:Sufu
uniprot id: A0A6I9LQS9
uniprot id: A0A6I9LWD0
uniprot id: A0A6J0DWP7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SUFU family.
messages: Cytoplasm
messages: Negative regulator in the hedgehog signaling pathway. Down-regulates GLI1-mediated transactivation of target genes. Part of a corepressor complex that acts on DNA-bound GLI1. May also act by linking GLI1 to BTRC and thereby targeting GLI1 to degradation by the proteasome. Sequesters GLI1, GLI2 and GLI3 in the cytoplasm, this effect is overcome by binding of STK36 to both SUFU and a GLI protein. Negative regulator of beta-catenin signaling. Regulates the formation of either the repressor form (GLI3R) or the activator form (GLI3A) of the full-length form of GLI3 (GLI3FL). GLI3FL is complexed with SUFU in the cytoplasm and is maintained in a neutral state. Without the Hh signal, the SUFU-GLI3 complex is recruited to cilia, leading to the efficient processing of GLI3FL into GLI3R. When Hh signaling is initiated, SUFU dissociates from GLI3FL and the latter translocates to the nucleus, where it is phosphorylated, destabilized, and converted to a transcriptional activator (GLI3A).
messages: Nucleus

230844:LOC102920030
gene id: 230844:LOC102920030
uniprot id: A0A6I9M521
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Serbp1
gene id: 230844:Serbp1
uniprot id: A0A6I9LVJ7
uniprot id: A0A6I9M1Y7
uniprot id: A0A6I9M3L2
uniprot id: A0A6I9M7F3
names: Similarity
messages: Belongs to the SERBP1-HABP4 family.

230844:Hpdl
gene id: 230844:Hpdl
uniprot id: A0A6I9LY56
names: Cofactor
names: Similarity
messages: Belongs to the 4HPPD family.
messages: Binds 1 Fe cation per subunit.

230844:Galntl5
gene id: 230844:Galntl5
uniprot id: A0A6I9M6M2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
messages: Membrane

230844:LOC102913709
gene id: 230844:LOC102913709
uniprot id: A0A6J0DMU8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gasdermin family.
messages: Cell membrane
messages: Membrane
messages: cytosol

230844:LOC102926821
gene id: 230844:LOC102926821
uniprot id: A0A6I9MKC3
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

230844:Zbed6
gene id: 230844:Zbed6
uniprot id: A0A6I9M624
names: Subcellular Location Annotation
messages: Nucleus

230844:LOC102916219
gene id: 230844:LOC102916219
uniprot id: A0A6I9LSN7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UDP-glycosyltransferase family.
messages: Membrane

230844:Cacng6
gene id: 230844:Cacng6
uniprot id: A0A6I9M108
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily.
messages: Membrane
messages: Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit.

230844:LOC102915724
gene id: 230844:LOC102915724
uniprot id: A0A6I9KUF9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NADPH--cytochrome P450 reductase family.
messages: Binds 1 FAD per monomer.
messages: Binds 1 FMN per monomer.
messages: Endoplasmic reticulum membrane
messages: In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
messages: In the N-terminal section; belongs to the flavodoxin family.
messages: This enzyme is required for electron transfer from NADP to cytochrome P450 in microsomes. It can also provide electron transfer to heme oxygenase and cytochrome B5.

230844:Oprd1
gene id: 230844:Oprd1
uniprot id: A0A6I9LA52
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Armc8
gene id: 230844:Armc8
uniprot id: A0A6I9L1Y7
uniprot id: A0A6I9L997
uniprot id: A0A6J0D496
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

230844:LOC102929077
gene id: 230844:LOC102929077
uniprot id: A0A6J0CF62
uniprot id: A0A6J0CHI5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:LOC102922582
gene id: 230844:LOC102922582
uniprot id: A0A6I9LF06
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:LOC102912527
gene id: 230844:LOC102912527
uniprot id: A0A6I9L725
names: Caution
names: Function
names: Similarity
names: Subunit
messages: As a result of hemolysis, hemoglobin is found to accumulate in the kidney and is secreted in the urine. Haptoglobin captures, and combines with free plasma hemoglobin to allow hepatic recycling of heme iron and to prevent kidney damage. Haptoglobin also acts as an antioxidant, has antibacterial activity and plays a role in modulating many aspects of the acute phase response. Hemoglobin/haptoglobin complexes are rapidly cleared by the macrophage CD163 scavenger receptor expressed on the surface of liver Kupfer cells through an endocytic lysosomal degradation pathway.
messages: Belongs to the peptidase S1 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Tetramer of two alpha and two beta chains; disulfide-linked (By similarity). The hemoglobin/haptoglobin complex is composed of a haptoglobin dimer bound to two hemoglobin alpha-beta dimers (By similarity). Interacts with CD163 (By similarity). Interacts with ERGIC3.

230844:Tmem177
gene id: 230844:Tmem177
uniprot id: A0A6I9LR39
names: Function
names: Similarity
messages: Belongs to the TMEM177 family.
messages: Plays a role in the early steps of cytochrome c oxidase subunit II (MT-CO2/COX2) maturation and is required for the stabilization of COX20 and the newly synthesized MT-CO2/COX2 protein.

230844:Arid3c
gene id: 230844:Arid3c
uniprot id: A0A6I9M1L1
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Homodimer.
messages: Nucleus
messages: Transcription factor.

230844:Sirt2
gene id: 230844:Sirt2
uniprot id: A0A6I9LMZ4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the sirtuin family. Class I subfamily.
messages: Binds 1 zinc ion per subunit.
messages: NAD-dependent protein deacetylase.

230844:Gdpgp1
gene id: 230844:Gdpgp1
uniprot id: A0A6I9KST4
uniprot id: A0A6I9KYI2
uniprot id: A0A6J0CYL6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GDPGP1 family.
messages: Cytoplasm
messages: Specific and highly efficient GDP-D-glucose phosphorylase regulating the levels of GDP-D-glucose in cells.

230844:Mvk
gene id: 230844:Mvk
uniprot id: A0A6I9M0M0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. Mevalonate kinase subfamily.
messages: Catalyzes the phosphorylation of mevalonate to mevalonate 5-phosphate, a key step in isoprenoid and cholesterol biosynthesis.
messages: Cytoplasm

230844:Tcp11l1
gene id: 230844:Tcp11l1
uniprot id: A0A6J0D5S8
names: Similarity
messages: Belongs to the TCP11 family.

230844:Jpt2
gene id: 230844:Jpt2
uniprot id: A0A6I9L232
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the JUPITER family.
messages: Cytoplasm
messages: Nucleus

230844:Sult6b1
gene id: 230844:Sult6b1
uniprot id: A0A6I9LQL3
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

230844:LOC102925951
gene id: 230844:LOC102925951
uniprot id: A0A6I9MEE3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:LOC102904422
gene id: 230844:LOC102904422
uniprot id: A0A6I9L5Y6
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

230844:Steap3
gene id: 230844:Steap3
uniprot id: A0A6I9LR44
uniprot id: A0A6J0DJ27
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STEAP family.
messages: Endosome membrane
messages: Membrane

230844:LOC102919167
gene id: 230844:LOC102919167
uniprot id: A0A6I9MJ28
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Atf7ip2
gene id: 230844:Atf7ip2
uniprot id: A0A6I9LRW3
uniprot id: A0A6J0DSN1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MCAF family.
messages: Nucleus

230844:LOC102925535
gene id: 230844:LOC102925535
uniprot id: A0A6I9M5V7
names: Similarity
names: Subunit
messages: Belongs to the histone H3 family.
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

230844:Srp68
gene id: 230844:Srp68
uniprot id: A0A6I9ME13
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SRP68 family.
messages: Component of the signal recognition particle (SRP) complex, a ribonucleoprotein complex that mediates the cotranslational targeting of secretory and membrane proteins to the endoplasmic reticulum (ER). The SRP complex interacts with the signal sequence in nascent secretory and membrane proteins and directs them to the membrane of the ER.
messages: Cytoplasm
messages: nucleolus

230844:P2rx5
gene id: 230844:P2rx5
uniprot id: A0A6J0CDI4
uniprot id: A0A6J0CFL6
uniprot id: A0A6J0CG88
uniprot id: A0A6J0CHJ8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the P2X receptor family.
messages: Functional P2XRs are organized as homomeric and heteromeric trimers.
messages: Membrane
messages: Receptor for ATP that acts as a ligand-gated ion channel.

230844:Tm6sf2
gene id: 230844:Tm6sf2
uniprot id: A0A6I9MK26
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TM6SF family.
messages: Membrane

230844:LOC102926537
gene id: 230844:LOC102926537
uniprot id: A0A6I9LW54
names: Subcellular Location Annotation
messages: Membrane

230844:Cystm1
gene id: 230844:Cystm1
uniprot id: A0A6J0EES2
names: Similarity
messages: Belongs to the CYSTM1 family.

230844:Capza2
gene id: 230844:Capza2
uniprot id: A0A6I9M7V4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the F-actin-capping protein alpha subunit family.
messages: F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.
messages: Heterodimer of an alpha and a beta subunit.

230844:Pomt2
gene id: 230844:Pomt2
uniprot id: A0A6I9LTZ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 39 family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Transfers mannose from Dol-P-mannose to Ser or Thr residues on proteins.

230844:Atp5f1a
gene id: 230844:Atp5f1a
uniprot id: A0A6I9KZE1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

230844:Fermt3
gene id: 230844:Fermt3
uniprot id: A0A6I9LQM6
names: Similarity
messages: Belongs to the kindlin family.

230844:Il17f
gene id: 230844:Il17f
uniprot id: A0A6J0EGF4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IL-17 family.
messages: Secreted

230844:LOC102918423
gene id: 230844:LOC102918423
uniprot id: A0A6I9M2H9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Glra1
gene id: 230844:Glra1
uniprot id: A0A6I9LLN2
uniprot id: A0A6J0DWG0
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family. Glycine receptor (TC 1.A.9.3) subfamily. GLRA1 sub-subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Perikaryon
messages: Postsynaptic cell membrane
messages: Synapse
messages: Synaptic cell membrane
messages: dendrite

230844:Tomm20l
gene id: 230844:Tomm20l
uniprot id: A0A6I9LUS8
uniprot id: A0A6J0E9R0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Tom20 family.
messages: Membrane
messages: Mitochondrion outer membrane

230844:Mrps18b
gene id: 230844:Mrps18b
uniprot id: A0A6I9MEA2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial ribosomal protein bS18 family. Mitochondrion-specific ribosomal protein mS40 subfamily.
messages: Mitochondrion

230844:Ppat
gene id: 230844:Ppat
uniprot id: A0A6I9MNF8
names: Cofactor
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.

230844:Snx6
gene id: 230844:Snx6
uniprot id: A0A6J0CT37
names: Similarity
messages: Belongs to the sorting nexin family.

230844:Mark2
gene id: 230844:Mark2
uniprot id: A0A6I9LBK3
uniprot id: A0A6I9LLI8
uniprot id: A0A6I9LQN7
uniprot id: A0A6J0DFV9
uniprot id: A0A6J0DI50
uniprot id: A0A6J0DI81
uniprot id: A0A6J0DIH0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. SNF1 subfamily.
messages: dendrite

230844:Tnn
gene id: 230844:Tnn
uniprot id: A0A6I9KZ75
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tenascin family.
messages: extracellular matrix

230844:Tmem192
gene id: 230844:Tmem192
uniprot id: A0A6I9LZK3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM192 family.
messages: Late endosome
messages: Lysosome membrane
messages: Membrane

230844:LOC102908954
gene id: 230844:LOC102908954
uniprot id: A0A6I9MKW1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Cdr2l
gene id: 230844:Cdr2l
uniprot id: A0A6I9MMR6
uniprot id: A0A6I9MP56
names: Similarity
messages: Belongs to the CDR2 family.

230844:Ctsa
gene id: 230844:Ctsa
uniprot id: A0A6I9L0H0
names: Similarity
messages: Belongs to the peptidase S10 family.

230844:Proz
gene id: 230844:Proz
uniprot id: A0A6I9LS03
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

230844:P2rx2
gene id: 230844:P2rx2
uniprot id: A0A6I9LHY3
uniprot id: A0A6I9LT63
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the P2X receptor family.
messages: Functional P2XRs are organized as homomeric and heteromeric trimers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Receptor for ATP that acts as a ligand-gated ion channel.

230844:Rspo4
gene id: 230844:Rspo4
uniprot id: A0A6I9LVG3
names: Similarity
messages: Belongs to the R-spondin family.

230844:Gadl1
gene id: 230844:Gadl1
uniprot id: A0A6I9L1P7
names: Similarity
names: Subunit
messages: Belongs to the group II decarboxylase family.
messages: Homodimer.

230844:Rabep1
gene id: 230844:Rabep1
uniprot id: A0A6J0CIT3
uniprot id: A0A6J0CK14
uniprot id: A0A6J0CKQ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the rabaptin family.
messages: Cytoplasm
messages: Early endosome
messages: Endosome

230844:LOC102904987
gene id: 230844:LOC102904987
uniprot id: A0A6I9M4R6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FGGY kinase family.
messages: Cytoplasm

230844:Pitpnm1
gene id: 230844:Pitpnm1
uniprot id: A0A6I9LB50
names: Similarity
messages: Belongs to the PtdIns transfer protein family. PI transfer class IIA subfamily.

230844:Dkk2
gene id: 230844:Dkk2
uniprot id: A0A6I9KTE4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dickkopf family.
messages: Secreted

230844:Gcfc2
gene id: 230844:Gcfc2
uniprot id: A0A6I9M1S5
names: Similarity
messages: Belongs to the GCF family.

230844:Slc25a34
gene id: 230844:Slc25a34
uniprot id: A0A6I9LDJ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

230844:Pex7
gene id: 230844:Pex7
uniprot id: A0A6I9M1V9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat peroxin-7 family.
messages: Peroxisome matrix
messages: cytosol

230844:Os9
gene id: 230844:Os9
uniprot id: A0A6I9KYG2
uniprot id: A0A6I9L5G4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OS-9 family.
messages: Endoplasmic reticulum lumen
messages: Lectin involved in the quality control of the secretory pathway. As a member of the endoplasmic reticulum-associated degradation lumenal (ERAD-L) surveillance system, targets misfolded endoplasmic reticulum lumenal glycoproteins for degradation.

230844:Gpx8
gene id: 230844:Gpx8
uniprot id: A0A6I9LJ14
names: Similarity
messages: Belongs to the glutathione peroxidase family.

230844:LOC102918969
gene id: 230844:LOC102918969
uniprot id: A0A6I9M6Z1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

230844:Slc30a2
gene id: 230844:Slc30a2
uniprot id: A0A6I9L2A2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily.
messages: Membrane

230844:Cpvl
gene id: 230844:Cpvl
uniprot id: A0A6J0CHG1
names: Similarity
messages: Belongs to the peptidase S10 family.

230844:Adgrl2
gene id: 230844:Adgrl2
uniprot id: A0A6J0DS53
uniprot id: A0A6J0DS84
names: Subcellular Location Annotation
messages: Membrane

230844:LOC102918902
gene id: 230844:LOC102918902
uniprot id: A0A6I9LU15
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Zdhhc17
gene id: 230844:Zdhhc17
uniprot id: A0A6I9L7V2
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Cytoplasmic vesicle membrane
messages: Golgi apparatus membrane
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

230844:LOC102912776
gene id: 230844:LOC102912776
uniprot id: A0A6I9LCH1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HSF family.
messages: Nucleus

230844:LOC102903676
gene id: 230844:LOC102903676
uniprot id: A0A6I9KZY2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TGF-beta family.
messages: Secreted

230844:Epha8
gene id: 230844:Epha8
uniprot id: A0A6I9LBW7
names: Subcellular Location Annotation
messages: Membrane

230844:Cdr2
gene id: 230844:Cdr2
uniprot id: A0A6I9LKN4
names: Similarity
messages: Belongs to the CDR2 family.

230844:Ednrb
gene id: 230844:Ednrb
uniprot id: A0A6I9LF28
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Vstm5
gene id: 230844:Vstm5
uniprot id: A0A6I9LZL3
names: Subcellular Location Annotation
messages: Membrane

230844:LOC102922251
gene id: 230844:LOC102922251
uniprot id: A0A6I9L890
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:C5H9orf64
gene id: 230844:C5H9orf64
uniprot id: A0A6I9LF29
names: Function
names: Similarity
messages: Belongs to the QNG1 protein family.
messages: Catalyzes the hydrolysis of queuosine 5'-phosphate, releasing the nucleobase queuine (q). Is required for salvage of queuine from exogenous queuosine (Q) that is imported and then converted to queuosine 5'-phosphate intracellularly.

230844:LOC102912634
gene id: 230844:LOC102912634
uniprot id: A0A6I9KYK8
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.

230844:Acvr1
gene id: 230844:Acvr1
uniprot id: A0A6I9LTC5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
messages: Membrane

230844:Hyou1
gene id: 230844:Hyou1
uniprot id: A0A6I9LYH5
names: Similarity
messages: Belongs to the heat shock protein 70 family.

230844:Myf5
gene id: 230844:Myf5
uniprot id: A0A6I9LIF9
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Efficient DNA binding requires dimerization with another bHLH protein.
messages: Induces fibroblasts to differentiate into myoblasts. Acts as a transcriptional activator that promotes transcription of muscle-specific target genes and plays a role in muscle differentiation.
messages: Nucleus

230844:Coq4
gene id: 230844:Coq4
uniprot id: A0A6I9LRW6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the COQ4 family.
messages: Component of a multi-subunit COQ enzyme complex, composed of at least COQ3, COQ4, COQ5, COQ6, COQ7 and COQ9.
messages: Component of the coenzyme Q biosynthetic pathway. May play a role in organizing a multi-subunit COQ enzyme complex required for coenzyme Q biosynthesis. Required for steady-state levels of other COQ polypeptides.
messages: Mitochondrion inner membrane

230844:Foxn4
gene id: 230844:Foxn4
uniprot id: A0A6I9M0M5
uniprot id: A0A6I9MH17
names: Subcellular Location Annotation
messages: Nucleus

230844:LOC102911696
gene id: 230844:LOC102911696
uniprot id: A0A6I9LH20
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Fgf6
gene id: 230844:Fgf6
uniprot id: A0A6I9M1N0
names: Similarity
messages: Belongs to the heparin-binding growth factors family.

230844:LOC102906438
gene id: 230844:LOC102906438
uniprot id: A0A6I9M7H5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2B family.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

230844:LOC102925955
gene id: 230844:LOC102925955
uniprot id: A0A6I9MFU5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:LOC102913206
gene id: 230844:LOC102913206
uniprot id: A0A6I9LPA7
names: Similarity
messages: Belongs to the cytochrome c oxidase VIIa family.

230844:LOC102919789
gene id: 230844:LOC102919789
uniprot id: A0A6J0CVS2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MHC class I family.
messages: Involved in the presentation of foreign antigens to the immune system.
messages: Membrane

230844:Ambn
gene id: 230844:Ambn
uniprot id: A0A6I9M274
uniprot id: A0A6I9M8T4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ameloblastin family.
messages: Involved in the mineralization and structural organization of enamel.
messages: extracellular matrix

230844:LOC102909080
gene id: 230844:LOC102909080
uniprot id: A0A6I9MAE4
names: Similarity
messages: Belongs to the histone H3 family.

230844:Gpr155
gene id: 230844:Gpr155
uniprot id: A0A6I9L6X3
names: Subcellular Location Annotation
messages: Membrane

230844:LOC102926285
gene id: 230844:LOC102926285
uniprot id: A0A6I9MKT6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Hoxc6
gene id: 230844:Hoxc6
uniprot id: A0A6I9LTB9
names: Subcellular Location Annotation
messages: Nucleus

230844:Ribc2
gene id: 230844:Ribc2
uniprot id: A0A6I9LAL1
names: Similarity
messages: Belongs to the RIB43A family.

230844:Inpp4a
gene id: 230844:Inpp4a
uniprot id: A0A6I9LPX6
uniprot id: A0A6J0DFA2
uniprot id: A0A6J0DFA5
uniprot id: A0A6J0DHG3
uniprot id: A0A6J0DHG9
uniprot id: A0A6J0DHX4
uniprot id: A0A6J0DN78
uniprot id: A0A6J0DN84
names: Similarity
messages: Belongs to the inositol 3,4-bisphosphate 4-phosphatase family.

230844:Plk4
gene id: 230844:Plk4
uniprot id: A0A6I9LNX6
names: Subcellular Location Annotation
messages: Cleavage furrow
messages: centriole

230844:Ogfr
gene id: 230844:Ogfr
uniprot id: A0A6I9LB71
names: Similarity
messages: Belongs to the opioid growth factor receptor family.

230844:Bst1
gene id: 230844:Bst1
uniprot id: A0A6I9M370
names: Similarity
messages: Belongs to the ADP-ribosyl cyclase family.

230844:Greb1l
gene id: 230844:Greb1l
uniprot id: A0A6J0CLG4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GREB1 family.
messages: Membrane

230844:Abcg5
gene id: 230844:Abcg5
uniprot id: A0A6I9LQ90
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCG family. Eye pigment precursor importer (TC 3.A.1.204) subfamily.
messages: Membrane

230844:Lclat1
gene id: 230844:Lclat1
uniprot id: A0A6I9LZY3
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.

230844:Tubb4a
gene id: 230844:Tubb4a
uniprot id: A0A6I9LG90
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.
messages: cytoskeleton

230844:Arl1
gene id: 230844:Arl1
uniprot id: A0A6I9LNJ2
names: Similarity
messages: Belongs to the small GTPase superfamily. Arf family.

230844:LOC102919285
gene id: 230844:LOC102919285
uniprot id: A0A6J0DIT7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calycin superfamily. Lipocalin family.
messages: Secreted

230844:Ak2
gene id: 230844:Ak2
uniprot id: A0A6I9M3W3
uniprot id: A0A6I9MF98
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family. AK2 subfamily.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism. Adenylate kinase activity is critical for regulation of the phosphate utilization and the AMP de novo biosynthesis pathways. Plays a key role in hematopoiesis.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Mitochondrion intermembrane space
messages: Monomer.

230844:Smu1
gene id: 230844:Smu1
uniprot id: A0A6I9L9N4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat SMU1 family.
messages: Nucleus speckle

230844:Pfdn6
gene id: 230844:Pfdn6
uniprot id: A0A6I9MGT5
names: Function
names: Similarity
messages: Belongs to the prefoldin subunit beta family.
messages: Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins.

230844:LOC102923423
gene id: 230844:LOC102923423
uniprot id: A0A6I9M1G4
names: Similarity
messages: Belongs to the cytochrome P450 family.

230844:Nit2
gene id: 230844:Nit2
uniprot id: A0A6I9MKL4
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.

230844:Uimc1
gene id: 230844:Uimc1
uniprot id: A0A6J0D7X4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RAP80 family.
messages: Nucleus

230844:LOC102912969
gene id: 230844:LOC102912969
uniprot id: A0A6I9MIE7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MHC class II family.
messages: Membrane

230844:Gtpbp3
gene id: 230844:Gtpbp3
uniprot id: A0A6I9MIW6
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.

230844:Actl7a
gene id: 230844:Actl7a
uniprot id: A0A6I9LUR7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the actin family.
messages: Golgi apparatus
messages: May play an important role in formation and fusion of Golgi-derived vesicles during acrosome biogenesis.
messages: Nucleus
messages: cytoskeleton

230844:Desi1
gene id: 230844:Desi1
uniprot id: A0A6I9LJA8
names: Similarity
messages: Belongs to the DeSI family.

230844:Spns3
gene id: 230844:Spns3
uniprot id: A0A6I9LXJ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Spinster (TC 2.A.1.49) family.
messages: Membrane

230844:Pdpr
gene id: 230844:Pdpr
uniprot id: A0A6I9LAM1
names: Similarity
messages: Belongs to the GcvT family.

230844:Syn3
gene id: 230844:Syn3
uniprot id: A0A6J0E000
names: Similarity
messages: Belongs to the synapsin family.

230844:Dkkl1
gene id: 230844:Dkkl1
uniprot id: A0A6I9M275
names: Subcellular Location Annotation
messages: Secreted

230844:LOC102920702
gene id: 230844:LOC102920702
uniprot id: A0A6I9MFG5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H4 family.
messages: Chromosome
messages: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

230844:LOC102915936
gene id: 230844:LOC102915936
uniprot id: A0A6I9M925
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

230844:Ptprf
gene id: 230844:Ptprf
uniprot id: A0A6I9M805
uniprot id: A0A6J0CL54
uniprot id: A0A6J0CN68
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Receptor class 2A subfamily.

230844:LOC102907875
gene id: 230844:LOC102907875
uniprot id: A0A6I9M9A2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:LOC102910197
gene id: 230844:LOC102910197
uniprot id: A0A6I9MDU6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

230844:Acly
gene id: 230844:Acly
uniprot id: A0A6I9M581
uniprot id: A0A6I9MC96
names: Function
names: Similarity
names: Subunit
messages: Catalyzes the cleavage of citrate into oxaloacetate and acetyl-CoA, the latter serving as common substrate for de novo cholesterol and fatty acid synthesis.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the succinate/malate CoA ligase alpha subunit family.
messages: In the N-terminal section; belongs to the succinate/malate CoA ligase beta subunit family.

230844:Mpped1
gene id: 230844:Mpped1
uniprot id: A0A6J0DMR5
names: Similarity
messages: Belongs to the UPF0046 family.

230844:Dynlt3
gene id: 230844:Dynlt3
uniprot id: A0A6I9L5I3
names: Similarity
messages: Belongs to the dynein light chain Tctex-type family.

230844:Ppt2
gene id: 230844:Ppt2
uniprot id: A0A6J0CN17
names: Similarity
messages: Belongs to the palmitoyl-protein thioesterase family.

230844:LOC102924298
gene id: 230844:LOC102924298
uniprot id: A0A6I9MG98
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2B family.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

230844:LOC102905086
gene id: 230844:LOC102905086
uniprot id: A0A6I9M539
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:P4hb
gene id: 230844:P4hb
uniprot id: A0A6I9M158
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein disulfide isomerase family.
messages: Endoplasmic reticulum lumen

230844:Tonsl
gene id: 230844:Tonsl
uniprot id: A0A6I9LS96
uniprot id: A0A6I9M8G8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Tonsoku family.
messages: Chromosome

230844:Eif4e2
gene id: 230844:Eif4e2
uniprot id: A0A6I9LI55
uniprot id: A0A6I9LSF5
uniprot id: A0A6I9LTF1
uniprot id: A0A6I9LXZ1
names: Similarity
messages: Belongs to the eukaryotic initiation factor 4E family.

230844:LOC102925248
gene id: 230844:LOC102925248
uniprot id: A0A6I9L6E8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Grk2
gene id: 230844:Grk2
uniprot id: A0A6I9LB69
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily.

230844:LOC102914497
gene id: 230844:LOC102914497
uniprot id: A0A6I9M972
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

230844:LOC102906144
gene id: 230844:LOC102906144
uniprot id: A0A6I9LWH1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Tob1
gene id: 230844:Tob1
uniprot id: A0A6I9L2C9
names: Similarity
messages: Belongs to the BTG family.

230844:LOC102915584
gene id: 230844:LOC102915584
uniprot id: A0A6I9LGK7
names: Similarity
messages: Belongs to the cytochrome P450 family.

230844:Gabrb2
gene id: 230844:Gabrb2
uniprot id: A0A6I9KV21
uniprot id: A0A6I9L201
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

230844:Mapk4
gene id: 230844:Mapk4
uniprot id: A0A6I9KS31
names: Similarity
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MAP kinase subfamily.

230844:Hbp1
gene id: 230844:Hbp1
uniprot id: A0A6I9M8S8
uniprot id: A0A6J0E6S1
names: Function
names: Subcellular Location Annotation
messages: Nucleus
messages: Transcriptional repressor that binds to the promoter region of target genes. Plays a role in the regulation of the cell cycle and of the Wnt pathway. Binds preferentially to the sequence 5'-TTCATTCATTCA-3'. Binding to the histone H1.0 promoter is enhanced by interaction with RB1. Disrupts the interaction between DNA and TCF4.

230844:Plcd1
gene id: 230844:Plcd1
uniprot id: A0A6J0DXP3
uniprot id: A0A6J0E5T5
names: Cofactor
messages: Binds 3 Ca(2+) ions per subunit. Two of the Ca(2+) ions are bound to the C2 domain.

230844:LOC102923070
gene id: 230844:LOC102923070
uniprot id: A0A6I9MM81
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Slc7a3
gene id: 230844:Slc7a3
uniprot id: A0A6J0DJG5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Cationic amino acid transporter (CAT) (TC 2.A.3.3) family.
messages: Cell membrane
messages: Membrane

230844:Npl
gene id: 230844:Npl
uniprot id: A0A6I9LIQ8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family. NanA subfamily.
messages: Cytoplasm
messages: Homotetramer.

230844:LOC102911960
gene id: 230844:LOC102911960
uniprot id: A0A6I9LXS9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Irf9
gene id: 230844:Irf9
uniprot id: A0A6I9M1E6
names: Subcellular Location Annotation
messages: Nucleus

230844:Elavl1
gene id: 230844:Elavl1
uniprot id: A0A6I9KYS2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRM elav family.
messages: Cytoplasm

230844:Dusp13
gene id: 230844:Dusp13
uniprot id: A0A6I9LJ17
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.

230844:Czib
gene id: 230844:Czib
uniprot id: A0A6I9LIM2
names: Similarity
messages: Belongs to the UPF0587 family.

230844:Edem1
gene id: 230844:Edem1
uniprot id: A0A6I9LU89
names: Similarity
messages: Belongs to the glycosyl hydrolase 47 family.

230844:Asphd2
gene id: 230844:Asphd2
uniprot id: A0A6J0DS10
names: Similarity
messages: Belongs to the aspartyl/asparaginyl beta-hydroxylase family.

230844:Nkiras2
gene id: 230844:Nkiras2
uniprot id: A0A6I9MCA3
names: Similarity
messages: Belongs to the small GTPase superfamily. Ras family. KappaB-Ras subfamily.

230844:Pcmtd2
gene id: 230844:Pcmtd2
uniprot id: A0A6J0CLZ0
uniprot id: A0A6J0CMI2
uniprot id: A0A6J0CPM4
names: Similarity
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.

230844:Masp1
gene id: 230844:Masp1
uniprot id: A0A6I9LJL6
uniprot id: A0A6I9LV23
uniprot id: A0A6J0DWX7
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

230844:LOC102919129
gene id: 230844:LOC102919129
uniprot id: A0A6J0EFY5
names: Similarity
messages: Belongs to the serpin family.

230844:Dnajb14
gene id: 230844:Dnajb14
uniprot id: A0A6J0D321
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

230844:Auh
gene id: 230844:Auh
uniprot id: A0A6I9L5D8
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

230844:Ift20
gene id: 230844:Ift20
uniprot id: A0A6I9LE42
names: Subcellular Location Annotation
messages: centriole
messages: cilium
messages: cis-Golgi network

230844:Eaf1
gene id: 230844:Eaf1
uniprot id: A0A6I9LM44
names: Similarity
messages: Belongs to the EAF family.

230844:Mrpl17
gene id: 230844:Mrpl17
uniprot id: A0A6I9LWI9
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL17 family.

230844:Afmid
gene id: 230844:Afmid
uniprot id: A0A6I9LTU8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the kynurenine formamidase family.
messages: Catalyzes the hydrolysis of N-formyl-L-kynurenine to L-kynurenine, the second step in the kynurenine pathway of tryptophan degradation. Kynurenine may be further oxidized to nicotinic acid, NAD(H) and NADP(H). Required for elimination of toxic metabolites.
messages: Homodimer.
messages: Nucleus
messages: The main chain amide nitrogen atoms of the second glycine and its adjacent residue in the HGGXW motif define the oxyanion hole, and stabilize the oxyanion that forms during the nucleophilic attack by the catalytic serine during substrate cleavage.
messages: cytosol

230844:Rfng
gene id: 230844:Rfng
uniprot id: A0A6I9LSX9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane

230844:Mettl16
gene id: 230844:Mettl16
uniprot id: A0A6I9LE14
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily. METTL16/RlmF family.
messages: RNA N6-methyltransferase that methylates adenosine residues at the N(6) position of a subset of RNAs and is involved in S-adenosyl-L-methionine homeostasis by regulating expression of MAT2A transcripts. Able to N6-methylate a subset of mRNAs and U6 small nuclear RNAs (U6 snRNAs). In contrast to the METTL3-METTL14 heterodimer, only able to methylate a limited number of RNAs: requires both a 5'UACAGAGAA-3' nonamer sequence and a specific RNA structure.

230844:Ccl24
gene id: 230844:Ccl24
uniprot id: A0A6I9KUY1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the intercrine beta (chemokine CC) family.
messages: Secreted

230844:Isl2
gene id: 230844:Isl2
uniprot id: A0A6I9KVE7
names: Subcellular Location Annotation
messages: Nucleus

230844:Hsd17b13
gene id: 230844:Hsd17b13
uniprot id: A0A6I9L2I5
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

230844:LOC102913648
gene id: 230844:LOC102913648
uniprot id: A0A6J0D8L5
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M2 family.
messages: Binds 1 zinc ion per subunit.

230844:Jak2
gene id: 230844:Jak2
uniprot id: A0A6I9M0Q6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. JAK subfamily.
messages: Cytoplasm
messages: Endomembrane system
messages: Nucleus

230844:LOC102904280
gene id: 230844:LOC102904280
uniprot id: A0A6I9KYB0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bombesin/neuromedin-B/ranatensin family.
messages: Secreted
messages: neuron projection

230844:Rbp1
gene id: 230844:Rbp1
uniprot id: A0A6I9L1G2
names: Similarity
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.

230844:Plcb4
gene id: 230844:Plcb4
uniprot id: A0A6I9LSY7
uniprot id: A0A6J0DPW6
uniprot id: A0A6J0DSS8
uniprot id: A0A6J0DT19
uniprot id: A0A6J0DYF8
names: Cofactor
names: Function
messages: Binds 1 Ca(2+) ion per subunit.
messages: The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes.

230844:Nkx2-3
gene id: 230844:Nkx2-3
uniprot id: A0A6I9M853
names: Subcellular Location Annotation
messages: Nucleus

230844:Fam83f
gene id: 230844:Fam83f
uniprot id: A0A6I9LHC5
names: Similarity
messages: Belongs to the FAM83 family.

230844:LOC102918310
gene id: 230844:LOC102918310
uniprot id: A0A6I9M037
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

230844:LOC102922294
gene id: 230844:LOC102922294
uniprot id: A0A6I9LXK7
uniprot id: A0A6J0E8U8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:LOC102906756
gene id: 230844:LOC102906756
uniprot id: A0A6I9M8Z9
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

230844:Zfyve16
gene id: 230844:Zfyve16
uniprot id: A0A6J0DI08
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Early endosome membrane

230844:Ap3m2
gene id: 230844:Ap3m2
uniprot id: A0A6J0DQG2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adaptor complexes medium subunit family.
messages: Cytoplasmic vesicle membrane
messages: Golgi apparatus

230844:Tspan2
gene id: 230844:Tspan2
uniprot id: A0A6I9LLL1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

230844:Tspan14
gene id: 230844:Tspan14
uniprot id: A0A6J0CU50
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

230844:Slc26a2
gene id: 230844:Slc26a2
uniprot id: A0A6J0DW48
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Membrane
messages: Sulfate transporter which mediates sulfate uptake into chondrocytes in order to maintain adequate sulfation of proteoglycans which is needed for cartilage development. Mediates electroneutral anion exchange of sulfate ions for oxalate ions, sulfate and oxalate ions for chloride and/or hydroxyl ions and chloride ions for bromide, iodide and nitrate ions. The coupling of sulfate transport to both hydroxyl and chloride ions likely serves to ensure transport at both acidic pH when most sulfate uptake is mediated by sulfate-hydroxide exchange and alkaline pH when most sulfate uptake is mediated by sulfate-chloride exchange. Essential for chondrocyte proliferation, differentiation and cell size expansion.

230844:LOC102905291
gene id: 230844:LOC102905291
uniprot id: A0A6I9LSS2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:LOC102903910
gene id: 230844:LOC102903910
uniprot id: A0A6I9L9W9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Slc37a3
gene id: 230844:Slc37a3
uniprot id: A0A6J0EEQ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Organophosphate:Pi antiporter (OPA) (TC 2.A.1.4) family.
messages: Membrane

230844:Trit1
gene id: 230844:Trit1
uniprot id: A0A6I9MA82
names: Function
names: Similarity
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37.

230844:Awat2
gene id: 230844:Awat2
uniprot id: A0A6I9LRK2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the diacylglycerol acyltransferase family.
messages: Endoplasmic reticulum membrane

230844:Gnl2
gene id: 230844:Gnl2
uniprot id: A0A6I9LNZ8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. NOG2 subfamily.
messages: GTPase that associates with pre-60S ribosomal subunits in the nucleolus and is required for their nuclear export and maturation.
messages: nucleolus

230844:Galns
gene id: 230844:Galns
uniprot id: A0A6I9LS95
uniprot id: A0A6J0DZH4
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sulfatase family.
messages: Binds 1 Ca(2+) ion per subunit.
messages: Homodimer.
messages: Lysosome

230844:Tfdp2
gene id: 230844:Tfdp2
uniprot id: A0A6I9L1H2
uniprot id: A0A6I9L9C2
uniprot id: A0A6I9LD15
uniprot id: A0A6J0D242
uniprot id: A0A6J0D336
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the E2F/DP family.
messages: Nucleus

230844:Csnk2a2
gene id: 230844:Csnk2a2
uniprot id: A0A6J0D8R8
uniprot id: A0A6J0DB21
names: Similarity
messages: Belongs to the protein kinase superfamily.

230844:Nefh
gene id: 230844:Nefh
uniprot id: A0A6I9KXJ7
names: Similarity
messages: Belongs to the intermediate filament family.

230844:LOC102921614
gene id: 230844:LOC102921614
uniprot id: A0A6I9L3S9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MCAF family.
messages: Nucleus

230844:Palm
gene id: 230844:Palm
uniprot id: A0A6I9L6W2
uniprot id: A0A6I9LJR4
uniprot id: A0A6J0DBI6
names: Similarity
messages: Belongs to the paralemmin family.

230844:LOC102905469
gene id: 230844:LOC102905469
uniprot id: A0A6I9MNQ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Ifrd2
gene id: 230844:Ifrd2
uniprot id: A0A6I9LJZ5
names: Similarity
messages: Belongs to the IFRD family.

230844:Dhh
gene id: 230844:Dhh
uniprot id: A0A6I9L7M6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the hedgehog family.
messages: Cell membrane
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Membrane
messages: Multimer.
messages: The C-terminal part of the hedgehog protein precursor displays an autoproteolysis activity that results in the cleavage of the full-length protein into two parts (N-product and C-product). In addition, the C-terminal part displays a cholesterol transferase activity that results by the covalent attachment of a cholesterol moiety to the C-terminal of the newly generated N-product.
messages: The dually lipidated hedgehog protein N-product is a morphogen which is essential for a variety of patterning events during development.

230844:Slc18a3
gene id: 230844:Slc18a3
uniprot id: A0A6I9LCI5
names: Subcellular Location Annotation
messages: Membrane

230844:Tmem168
gene id: 230844:Tmem168
uniprot id: A0A6I9LK86
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM168 family.
messages: Membrane
messages: Nucleus membrane

230844:Mocs2
gene id: 230844:Mocs2
uniprot id: A0A6I9L938
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MoaE family. MOCS2B subfamily.
messages: Catalytic subunit of the molybdopterin synthase complex, a complex that catalyzes the conversion of precursor Z into molybdopterin. Acts by mediating the incorporation of 2 sulfur atoms from thiocarboxylated MOCS2A into precursor Z to generate a dithiolene group.
messages: Heterotetramer; composed of 2 small (MOCS2A) and 2 large (MOCS2B) subunits.
messages: This protein is produced by a bicistronic gene which also produces the small subunit (MOCS2A) from an overlapping reading frame.
messages: cytosol

230844:Cpa3
gene id: 230844:Cpa3
uniprot id: A0A6I9M0F7
names: Similarity
messages: Belongs to the peptidase M14 family.

230844:Lsm3
gene id: 230844:Lsm3
uniprot id: A0A6I9KWT9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the snRNP Sm proteins family.
messages: Binds specifically to the 3'-terminal U-tract of U6 snRNA.
messages: LSm subunits form a heteromer with a doughnut shape.
messages: Nucleus

230844:Erlin2
gene id: 230844:Erlin2
uniprot id: A0A6I9LFT0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the band 7/mec-2 family.
messages: Endoplasmic reticulum membrane
messages: Mediates the endoplasmic reticulum-associated degradation (ERAD) of inositol 1,4,5-trisphosphate receptors (IP3Rs). Involved in regulation of cellular cholesterol homeostasis by regulation the SREBP signaling pathway.
messages: Membrane

230844:Polr3h
gene id: 230844:Polr3h
uniprot id: A0A6I9LKE6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic RPB7/RPC8 RNA polymerase subunit family.
messages: DNA-dependent RNA polymerase which catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Nucleus

230844:C7H15orf65
gene id: 230844:C7H15orf65
uniprot id: A0A6I9L686
names: Subcellular Location Annotation
names: Subunit
messages: Interacts with CFAP53, ODAD1 and ODAD3; the interactions link the outer dynein arms docking complex (ODA-DC) to the internal microtubule inner proteins (MIP) in cilium axoneme.
messages: cilium axoneme

230844:Tagln3
gene id: 230844:Tagln3
uniprot id: A0A6I9L2I7
names: Similarity
messages: Belongs to the calponin family.

230844:Slc6a8
gene id: 230844:Slc6a8
uniprot id: A0A6I9M4A4
names: Similarity
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. SLC6A8 subfamily.
messages: Cell membrane
messages: Membrane

230844:Cd244
gene id: 230844:Cd244
uniprot id: A0A6J0E7T3
names: Subcellular Location Annotation
messages: Membrane

230844:LOC102918043
gene id: 230844:LOC102918043
uniprot id: A0A6I9MHJ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:B4galnt2
gene id: 230844:B4galnt2
uniprot id: A0A6J0E4W3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family.
messages: Golgi apparatus membrane
messages: Membrane

230844:Faim2
gene id: 230844:Faim2
uniprot id: A0A6I9L7S5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

230844:Lsm14b
gene id: 230844:Lsm14b
uniprot id: A0A6I9LEY0
names: Similarity
messages: Belongs to the LSM14 family.

230844:Ugdh
gene id: 230844:Ugdh
uniprot id: A0A6I9L862
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.
messages: Homohexamer.
messages: Involved in the biosynthesis of glycosaminoglycans; hyaluronan, chondroitin sulfate, and heparan sulfate.

230844:Polr3f
gene id: 230844:Polr3f
uniprot id: A0A6I9LIH8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic RPC34/RPC39 RNA polymerase subunit family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs.
messages: Nucleus

230844:Agap2
gene id: 230844:Agap2
uniprot id: A0A6I9L8S5
names: Similarity
messages: Belongs to the centaurin gamma-like family.

230844:LOC107401607
gene id: 230844:LOC107401607
uniprot id: A0A6J0DGY0
names: Similarity
messages: Belongs to the learning-associated protein family.

230844:Samd4b
gene id: 230844:Samd4b
uniprot id: A0A6I9LLZ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SMAUG family.
messages: Cytoplasm

230844:Hdhd3
gene id: 230844:Hdhd3
uniprot id: A0A6I9LMR6
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.

230844:Aif1l
gene id: 230844:Aif1l
uniprot id: A0A6I9LR01
names: Subcellular Location Annotation
messages: ruffle membrane

230844:LOC102921437
gene id: 230844:LOC102921437
uniprot id: A0A6I9MJR7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Armc1
gene id: 230844:Armc1
uniprot id: A0A6I9L897
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In association with mitochondrial contact site and cristae organizing system (MICOS) complex components and mitochondrial outer membrane sorting assembly machinery (SAM) complex components may regulate mitochondrial dynamics playing a role in determining mitochondrial length, distribution and motility.
messages: Membrane
messages: Mitochondrion outer membrane

230844:Gpn3
gene id: 230844:Gpn3
uniprot id: A0A6I9KU06
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GPN-loop GTPase family.
messages: Binds to RNA polymerase II (RNAPII).
messages: Small GTPase required for proper localization of RNA polymerase II (RNAPII). May act at an RNAP assembly step prior to nuclear import.
messages: Small GTPase required for proper nuclear import of RNA polymerase II and III (RNAPII and RNAPIII). May act at an RNAP assembly step prior to nuclear import.

230844:Ophn1
gene id: 230844:Ophn1
uniprot id: A0A6J0DJN8
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Postsynapse
messages: Presynapse
messages: dendrite

230844:Alx1
gene id: 230844:Alx1
uniprot id: A0A6I9LYU1
names: Subcellular Location Annotation
messages: Nucleus

230844:Gprin3
gene id: 230844:Gprin3
uniprot id: A0A6J0CNZ7
names: Function
messages: May be involved in neurite outgrowth.

230844:Galnt16
gene id: 230844:Galnt16
uniprot id: A0A6J0CXT5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
messages: Golgi apparatus membrane
messages: Membrane

230844:Olfml2b
gene id: 230844:Olfml2b
uniprot id: A0A6I9M1D5
uniprot id: A0A6J0CLH1
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

230844:Cd52
gene id: 230844:Cd52
uniprot id: A0A6I9L2Z3
names: Function
names: Subcellular Location Annotation
messages: May play a role in carrying and orienting carbohydrate, as well as having a more specific role.
messages: Membrane

230844:LOC102911656
gene id: 230844:LOC102911656
uniprot id: A0A6I9M0J4
names: Subcellular Location Annotation
messages: Nucleus

230844:LOC102922669
gene id: 230844:LOC102922669
uniprot id: A0A6I9MDL6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Cers2
gene id: 230844:Cers2
uniprot id: A0A6I9LP34
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Nucleus

230844:Rab27b
gene id: 230844:Rab27b
uniprot id: A0A6J0DMS7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Endosome
messages: Late endosome
messages: Membrane

230844:Kifc3
gene id: 230844:Kifc3
uniprot id: A0A6J0E1R4
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

230844:Inpp5j
gene id: 230844:Inpp5j
uniprot id: A0A6I9L4Q7
names: Similarity
messages: Belongs to the inositol 1,4,5-trisphosphate 5-phosphatase type II family.

230844:Mocos
gene id: 230844:Mocos
uniprot id: A0A6I9LP60
names: Function
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. MOCOS subfamily.
messages: Sulfurates the molybdenum cofactor. Sulfation of molybdenum is essential for xanthine dehydrogenase (XDH) and aldehyde oxidase (ADO) enzymes in which molybdenum cofactor is liganded by 1 oxygen and 1 sulfur atom in active form.

230844:Fras1
gene id: 230844:Fras1
uniprot id: A0A6I9L1S9
names: Similarity
messages: Belongs to the FRAS1 family.

230844:Rapgef6
gene id: 230844:Rapgef6
uniprot id: A0A6I9LJ84
uniprot id: A0A6I9LUM8
uniprot id: A0A6I9LZ24
uniprot id: A0A6J0DSQ7
uniprot id: A0A6J0DSR2
uniprot id: A0A6J0DU74
uniprot id: A0A6J0DU78
uniprot id: A0A6J0DU81
uniprot id: A0A6J0DVH5
uniprot id: A0A6J0DVI0
uniprot id: A0A6J0DWD3
uniprot id: A0A6J0DWE0
uniprot id: A0A6J0DWE5
uniprot id: A0A6J0E0Z0
uniprot id: A0A6J0E0Z4
uniprot id: A0A6J0E0Z7
names: Similarity
messages: Belongs to the RAPGEF2 family.

230844:Iscu
gene id: 230844:Iscu
uniprot id: A0A6I9M0N1
names: Function
names: Similarity
messages: Belongs to the NifU family.
messages: Mitochondrial scaffold protein, of the core iron-sulfur cluster (ISC) assembly complex, that provides the structural architecture on which the [2Fe-2S] clusters are assembled. The core iron-sulfur cluster (ISC) assembly complex is involved in the de novo synthesis of a [2Fe-2S] cluster, the first step of the mitochondrial iron-sulfur protein biogenesis. This process is initiated by the cysteine desulfurase complex (NFS1:LYRM4:NDUFAB1) that produces persulfide which is delivered on the scaffold protein ISCU in a FXN-dependent manner. Then this complex is stabilized by FDX2 which provides reducing equivalents to accomplish the [2Fe-2S] cluster assembly. Finally, the [2Fe-2S] cluster is transferred from ISCU to chaperone proteins, including HSCB, HSPA9 and GLRX5. Exists as two slow interchanging conformational states, a structured (S) and disordered (D) form. May modulate NFS1 desulfurase activity in a zinc-dependent manner. Modulates the interaction between FXN and the cysteine desulfurase complex.

230844:LOC102905389
gene id: 230844:LOC102905389
uniprot id: A0A6J0DXU8
names: Similarity
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. GB1/RHD3 GTPase family.

230844:LOC102912988
gene id: 230844:LOC102912988
uniprot id: A0A6J0DGR5
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL42 family.

230844:Chst12
gene id: 230844:Chst12
uniprot id: A0A6I9LUU7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 2 family.
messages: Golgi apparatus membrane
messages: Membrane

230844:LOC102923555
gene id: 230844:LOC102923555
uniprot id: A0A6J0EB34
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Hmces
gene id: 230844:Hmces
uniprot id: A0A6I9MEP6
names: Function
names: Similarity
messages: Belongs to the SOS response-associated peptidase family.
messages: Sensor of abasic sites in single-stranded DNA (ssDNA) required to preserve genome integrity by promoting error-free repair of abasic sites. Acts as an enzyme that recognizes and binds abasic sites in ssDNA at replication forks and chemically modifies the lesion by forming a covalent cross-link with DNA: forms a stable thiazolidine linkage between a ring-opened abasic site and the alpha-amino and sulfhydryl substituents of its N-terminal catalytic cysteine residue. The HMCES DNA-protein cross-link is then degraded by the proteasome. Promotes error-free repair of abasic sites by acting as a 'suicide' enzyme that is degraded, thereby protecting abasic sites from translesion synthesis (TLS) polymerases and endonucleases that are error-prone and would generate mutations and double-strand breaks. Has preference for ssDNA, but can also accommodate double-stranded DNA with 3' or 5' overhang (dsDNA), and dsDNA-ssDNA 3' junction.

230844:LOC102926041
gene id: 230844:LOC102926041
uniprot id: A0A6I9M5B2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

230844:Tcf25
gene id: 230844:Tcf25
uniprot id: A0A6I9LNV7
uniprot id: A0A6I9LSB7
uniprot id: A0A6I9LZD0
uniprot id: A0A6I9M0I3
uniprot id: A0A6J0E7J9
names: Similarity
messages: Belongs to the TCF25 family.

230844:Cdh15
gene id: 230844:Cdh15
uniprot id: A0A6I9LSA0
names: Function
names: Subcellular Location Annotation
messages: Cadherins are calcium-dependent cell adhesion proteins.
messages: Cell membrane
messages: Membrane

230844:Pno1
gene id: 230844:Pno1
uniprot id: A0A6I9M2A0
names: Subcellular Location Annotation
messages: nucleolus

230844:Vta1
gene id: 230844:Vta1
uniprot id: A0A6I9LCE5
uniprot id: A0A6J0D7Y8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VTA1 family.
messages: Cytoplasm
messages: Endosome membrane
messages: Membrane

230844:Ddit4l
gene id: 230844:Ddit4l
uniprot id: A0A6I9KZ38
names: Similarity
messages: Belongs to the DDIT4 family.

230844:Cldn1
gene id: 230844:Cldn1
uniprot id: A0A6I9LM46
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

230844:Pgap2
gene id: 230844:Pgap2
uniprot id: A0A6J0CHW3
uniprot id: A0A6J0CHW8
uniprot id: A0A6J0CIH6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PGAP2 family.
messages: Interacts with PGAP2IP.
messages: Involved in the lipid remodeling steps of GPI-anchor maturation. Required for stable expression of GPI-anchored proteins at the cell surface.
messages: Membrane

230844:Rbm15
gene id: 230844:Rbm15
uniprot id: A0A6J0DF38
names: Similarity
messages: Belongs to the RRM Spen family.

230844:Gatad2a
gene id: 230844:Gatad2a
uniprot id: A0A6I9MHV1
uniprot id: A0A6J0CN56
uniprot id: A0A6J0CQ30
names: Subcellular Location Annotation
messages: Nucleus

230844:Vcan
gene id: 230844:Vcan
uniprot id: A0A6I9LCN2
uniprot id: A0A6J0DHI2
uniprot id: A0A6J0DHJ9
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aggrecan/versican proteoglycan family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

230844:Gpr21
gene id: 230844:Gpr21
uniprot id: A0A6I9M943
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

230844:Ace
gene id: 230844:Ace
uniprot id: A0A6I9KZH8
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M2 family.
messages: Binds 2 Zn(2+) ions per subunit.

230844:Slc22a1
gene id: 230844:Slc22a1
uniprot id: A0A6I9LJB4
names: Similarity
messages: Belongs to the major facilitator (TC 2.A.1) superfamily. Organic cation transporter (TC 2.A.1.19) family.

230844:Hsd17b2
gene id: 230844:Hsd17b2
uniprot id: A0A6I9LXL0
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

230844:Slc25a42
gene id: 230844:Slc25a42
uniprot id: A0A6I9MHT2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

230844:LOC102909660
gene id: 230844:LOC102909660
uniprot id: A0A6I9M799
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:LOC102910359
gene id: 230844:LOC102910359
uniprot id: A0A6I9LNF4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:LOC102925207
gene id: 230844:LOC102925207
uniprot id: A0A6J0EE56
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL42 family.

230844:LOC102922673
gene id: 230844:LOC102922673
uniprot id: A0A6I9MN09
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Usp2
gene id: 230844:Usp2
uniprot id: A0A6I9LYG2
uniprot id: A0A6I9MBV8
names: Function
names: Similarity
messages: Belongs to the peptidase C19 family.
messages: Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes.

230844:LOC102927331
gene id: 230844:LOC102927331
uniprot id: A0A6J0DM53
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Peli1
gene id: 230844:Peli1
uniprot id: A0A6I9LC90
names: Function
names: Similarity
messages: Belongs to the pellino family.
messages: E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins.

230844:Fancc
gene id: 230844:Fancc
uniprot id: A0A6I9LNQ0
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the multisubunit FA complex composed of FANCA, FANCB, FANCC, FANCE, FANCF, FANCG, FANCL/PHF9 and FANCM. This complex may also include HSP70.
messages: DNA repair protein that may operate in a postreplication repair or a cell cycle checkpoint function. May be implicated in interstrand DNA cross-link repair and in the maintenance of normal chromosome stability. Upon IFNG induction, may facilitate STAT1 activation by recruiting STAT1 to IFNGR1.
messages: Nucleus

230844:LOC102922269
gene id: 230844:LOC102922269
uniprot id: A0A6I9LFU2
names: Function
names: Similarity
messages: Belongs to the cytochrome c oxidase subunit 6B.
messages: Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.

230844:Lyrm1
gene id: 230844:Lyrm1
uniprot id: A0A6J0E2T4
uniprot id: A0A6J0E2T7
names: Similarity
messages: Belongs to the complex I LYR family.

230844:Tdrd7
gene id: 230844:Tdrd7
uniprot id: A0A6I9L9P9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TDRD7 family.
messages: Component of specific cytoplasmic RNA granules involved in post-transcriptional regulation of specific genes: probably acts by binding to specific mRNAs and regulating their translation. Required for lens transparency during lens development, by regulating translation of genes such as CRYBB3 and HSPB1 in the developing lens. Also required during spermatogenesis.
messages: Cytoplasm
messages: Found in a mRNP complex, at least composed of TDRD1, TDRD6, TDRD7 and DDX4. Found in a complex containing CABLES1, CDK16 and CDK17. Interacts with CABLES1, CDK17 and PIWIL1.

230844:Gpr173
gene id: 230844:Gpr173
uniprot id: A0A6J0CKA7
names: Subcellular Location Annotation
messages: Membrane

230844:Fam131c
gene id: 230844:Fam131c
uniprot id: A0A6I9L9Y4
names: Similarity
messages: Belongs to the FAM131 family.

230844:LOC102927706
gene id: 230844:LOC102927706
uniprot id: A0A6I9MCY2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Pth2
gene id: 230844:Pth2
uniprot id: A0A6I9LLX3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the parathyroid hormone family.
messages: Secreted

230844:Sec13
gene id: 230844:Sec13
uniprot id: A0A6I9M9B2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat SEC13 family.
messages: Lysosome membrane

230844:Avpr1a
gene id: 230844:Avpr1a
uniprot id: D7PCW8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily.
messages: Cell membrane
messages: Membrane
messages: Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate a phosphatidyl-inositol-calcium second messenger system.

230844:Myo9b
gene id: 230844:Myo9b
uniprot id: A0A6J0E5N0
uniprot id: A0A6J0E5P0
uniprot id: A0A6J0E5P6
uniprot id: A0A6J0E7J7
uniprot id: A0A6J0E7K2
uniprot id: A0A6J0E996
uniprot id: A0A6J0E9A2
uniprot id: A0A6J0EBJ4
uniprot id: A0A6J0EBK2
uniprot id: A0A6J0ED27
uniprot id: A0A6J0ED32
uniprot id: A0A6J0ED36
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.

230844:Fscn3
gene id: 230844:Fscn3
uniprot id: A0A6I9L8Z7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fascin family.
messages: cytoskeleton

230844:Gdpd3
gene id: 230844:Gdpd3
uniprot id: A0A6I9L5X7
names: Similarity
messages: Belongs to the glycerophosphoryl diester phosphodiesterase family.

230844:LOC102918660
gene id: 230844:LOC102918660
uniprot id: A0A6I9MMU6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Iqsec1
gene id: 230844:Iqsec1
uniprot id: A0A6I9KWT2
uniprot id: A0A6I9L3J1
uniprot id: A0A6I9L729
uniprot id: A0A6J0CMY7
uniprot id: A0A6J0CMZ2
uniprot id: A0A6J0CMZ6
uniprot id: A0A6J0CN00
uniprot id: A0A6J0CP40
names: Similarity
messages: Belongs to the BRAG family.

230844:Slc20a2
gene id: 230844:Slc20a2
uniprot id: A0A6I9LR36
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
messages: Membrane
messages: Sodium-phosphate symporter.

230844:Ccdc181
gene id: 230844:Ccdc181
uniprot id: A0A6J0D0V7
uniprot id: A0A6J0D6L2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CCDC181 family.
messages: Microtubule-binding protein that localizes to the microtubular manchette of elongating spermatids.
messages: cytoskeleton
messages: flagellum

230844:Lmod2
gene id: 230844:Lmod2
uniprot id: A0A6I9LQQ3
names: Subcellular Location Annotation
messages: cytoskeleton

230844:LOC102922448
gene id: 230844:LOC102922448
uniprot id: A0A6I9MGZ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:LOC102916341
gene id: 230844:LOC102916341
uniprot id: A0A6I9M677
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fatty acid desaturase type 1 family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: The histidine box domains are involved in binding the catalytic metal ions.

230844:Mpz
gene id: 230844:Mpz
uniprot id: A0A6I9LZU4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the myelin P0 protein family.
messages: Cell membrane
messages: Homodimer and homotetramer.
messages: Is an adhesion molecule necessary for normal myelination in the peripheral nervous system. It mediates adhesion between adjacent myelin wraps and ultimately drives myelin compaction.
messages: Membrane

230844:Mpv17l2
gene id: 230844:Mpv17l2
uniprot id: A0A6I9LRY6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peroxisomal membrane protein PXMP2/4 family.
messages: Membrane

230844:Fgf19
gene id: 230844:Fgf19
uniprot id: A0A6I9L569
names: Similarity
messages: Belongs to the heparin-binding growth factors family.

230844:Sorcs3
gene id: 230844:Sorcs3
uniprot id: A0A6I9LRR0
names: Similarity
messages: Belongs to the VPS10-related sortilin family. SORCS subfamily.

230844:Uhrf2
gene id: 230844:Uhrf2
uniprot id: A0A6I9LEE1
names: Domain
names: Function
names: Subcellular Location Annotation
messages: Multi domain E3 ubiquitin ligase that also plays a role in DNA methylation and histone modifications.
messages: Nucleus
messages: The YDG domain mediates the interaction with histone H3.
messages: The tudor-like regions specifically recognize and bind histone H3 unmethylated at 'Arg-2' (H3R2me0), while the PHD-type zinc finger specifically recognizes and binds histone H3 trimethylated at 'Lys-9' (H3K9me3).

230844:Syndig1
gene id: 230844:Syndig1
uniprot id: A0A6J0DVG7
names: Similarity
messages: Belongs to the CD225/Dispanin family.

230844:Slc43a2
gene id: 230844:Slc43a2
uniprot id: A0A6I9L6H8
uniprot id: A0A6I9LE35
names: Subcellular Location Annotation
messages: Membrane

230844:Trappc5
gene id: 230844:Trappc5
uniprot id: A0A6I9KS96
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAPP small subunits family. BET3 subfamily.
messages: Endoplasmic reticulum
messages: May play a role in vesicular transport from endoplasmic reticulum to Golgi.
messages: Part of the multisubunit TRAPP (transport protein particle) complex.
messages: cis-Golgi network

230844:Pcnt
gene id: 230844:Pcnt
uniprot id: A0A6J0CG94
uniprot id: A0A6J0CGP6
names: Subcellular Location Annotation
messages: centrosome

230844:LOC102917320
gene id: 230844:LOC102917320
uniprot id: A0A6I9MN73
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:LOC102909659
gene id: 230844:LOC102909659
uniprot id: A0A6I9M073
names: Similarity
names: Subunit
messages: Belongs to the histone H3 family.
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

230844:Prr15
gene id: 230844:Prr15
uniprot id: A0A6J0CHH5
names: Similarity
messages: Belongs to the PRR15 family.

230844:LOC102908168
gene id: 230844:LOC102908168
uniprot id: A0A6I9LVH9
names: Similarity
messages: Belongs to the strictosidine synthase family.

230844:Mapre2
gene id: 230844:Mapre2
uniprot id: A0A6I9LBY4
uniprot id: A0A6I9LP47
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MAPRE family.
messages: cytoskeleton

230844:Gtf2h3
gene id: 230844:Gtf2h3
uniprot id: A0A6I9KTW0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TFB4 family.
messages: Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to CAK, in RNA transcription by RNA polymerase II. In NER, TFIIH acts by opening DNA around the lesion to allow the excision of the damaged oligonucleotide and its replacement by a new DNA fragment. In transcription, TFIIH has an essential role in transcription initiation. When the pre-initiation complex (PIC) has been established, TFIIH is required for promoter opening and promoter escape. Phosphorylation of the C-terminal tail (CTD) of the largest subunit of RNA polymerase II by the kinase module CAK controls the initiation of transcription.
messages: Nucleus
messages: Part of a TFIID-containing RNA polymerase II pre-initiation complex that is composed of TBP and at least GTF2A1, GTF2A2, GTF2E1, GTF2E2, GTF2F1, GTF2H2, GTF2H3, GTF2H4, GTF2H5, GTF2B, TCEA1, ERCC2, ERCC3, TAF1, TAF2, TAF3, TAF4, TAF5, TAF6, TAF7, TAF8, TAF9, TAF10, TAF11, TAF12 and TAF13. Component of the 7-subunit TFIIH core complex composed of XPB/ERCC3, XPD/ERCC2, GTF2H1, GTF2H2, GTF2H3, GTF2H4 and GTF2H5, which is active in NER. The core complex associates with the 3-subunit CDK-activating kinase (CAK) module composed of CCNH/cyclin H, CDK7 and MNAT1 to form the 10-subunit holoenzyme (holo-TFIIH) active in transcription. Interacts with RARA; the interaction requires prior phosphorylation of RARA on 'Ser-369' which then enhances interaction of RARA with CDK7.

230844:Osbpl2
gene id: 230844:Osbpl2
uniprot id: A0A6J0D4N5
uniprot id: A0A6J0D5S1
names: Similarity
messages: Belongs to the OSBP family.

230844:Phpt1
gene id: 230844:Phpt1
uniprot id: A0A6I9LDT2
names: Function
names: Similarity
messages: Belongs to the janus family.
messages: Exhibits phosphohistidine phosphatase activity.

230844:LOC102905212
gene id: 230844:LOC102905212
uniprot id: A0A6I9M8Z3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Shtn1
gene id: 230844:Shtn1
uniprot id: A0A6I9LFY3
uniprot id: A0A6J0DAN4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the shootin family.
messages: Perikaryon
messages: axon
messages: cytoskeleton
messages: filopodium
messages: lamellipodium

230844:Trim67
gene id: 230844:Trim67
uniprot id: A0A6I9M530
names: Subcellular Location Annotation
messages: cytoskeleton

230844:Pi4kb
gene id: 230844:Pi4kb
uniprot id: A0A6I9MDI4
uniprot id: A0A6J0CKW9
names: Similarity
messages: Belongs to the PI3/PI4-kinase family. Type III PI4K subfamily.

230844:Iyd
gene id: 230844:Iyd
uniprot id: A0A6I9LJF8
names: Subcellular Location Annotation
messages: Cell membrane

230844:Grm2
gene id: 230844:Grm2
uniprot id: A0A6J0DH77
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 3 family.
messages: Cell membrane
messages: Membrane

230844:Galk2
gene id: 230844:Galk2
uniprot id: A0A6I9MH84
uniprot id: A0A6J0CKL0
uniprot id: A0A6J0CL44
names: Similarity
messages: Belongs to the GHMP kinase family. GalK subfamily.

230844:LOC102924683
gene id: 230844:LOC102924683
uniprot id: A0A6I9LZU8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

230844:Slc4a10
gene id: 230844:Slc4a10
uniprot id: A0A6I9LIR9
uniprot id: A0A6I9LL07
uniprot id: A0A6I9LL14
uniprot id: A0A6I9LT96
uniprot id: A0A6I9LTA2
uniprot id: A0A6I9LU50
uniprot id: A0A6I9LU52
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Basolateral cell membrane
messages: Belongs to the anion exchanger (TC 2.A.31) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Lateral cell membrane
messages: Membrane

230844:Tph2
gene id: 230844:Tph2
uniprot id: A0A6I9M268
names: Similarity
messages: Belongs to the biopterin-dependent aromatic amino acid hydroxylase family.

230844:Fam118a
gene id: 230844:Fam118a
uniprot id: A0A6J0DH53
names: Similarity
messages: Belongs to the FAM118 family.

230844:Itpr3
gene id: 230844:Itpr3
uniprot id: A0A6I9MKA4
uniprot id: A0A6I9MM60
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the InsP3 receptor family.
messages: Endoplasmic reticulum membrane
messages: Homotetramer.
messages: Membrane
messages: Receptor for inositol 1,4,5-trisphosphate, a second messenger that mediates the release of intracellular calcium.
messages: The receptor contains a calcium channel in its C-terminal extremity. Its large N-terminal cytoplasmic region has the ligand-binding site in the N-terminus and modulatory sites in the middle portion immediately upstream of the channel region.

230844:Adam33
gene id: 230844:Adam33
uniprot id: A0A6J0DU83
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

230844:Slc39a11
gene id: 230844:Slc39a11
uniprot id: A0A6I9L258
uniprot id: A0A6J0D2T0
names: Subcellular Location Annotation
messages: Membrane

230844:LOC102928991
gene id: 230844:LOC102928991
uniprot id: A0A6I9M9Z2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Mef2b
gene id: 230844:Mef2b
uniprot id: A0A6I9MEV0
uniprot id: A0A6J0CQ20
names: Subcellular Location Annotation
messages: Nucleus

230844:Tm9sf1
gene id: 230844:Tm9sf1
uniprot id: A0A6J0E2E0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nonaspanin (TM9SF) (TC 9.A.2) family.
messages: Membrane

230844:Cacng3
gene id: 230844:Cacng3
uniprot id: A0A6I9LAR8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily.
messages: Membrane

230844:LOC102916193
gene id: 230844:LOC102916193
uniprot id: A0A6I9LGS9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Ptpn14
gene id: 230844:Ptpn14
uniprot id: A0A6I9KW85
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class subfamily.
messages: cytoskeleton

230844:Psmb5
gene id: 230844:Psmb5
uniprot id: A0A6I9M1B4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1B family.
messages: Component of the proteasome complex.
messages: Component of the proteasome, a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.
messages: Cytoplasm
messages: Nucleus

230844:LOC102908626
gene id: 230844:LOC102908626
uniprot id: A0A6I9MCU4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the actin-binding proteins ADF family. Twinfilin subfamily.
messages: cytoskeleton

230844:LOC102921269
gene id: 230844:LOC102921269
uniprot id: A0A6I9M3U9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Tm9sf2
gene id: 230844:Tm9sf2
uniprot id: A0A6I9LH80
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nonaspanin (TM9SF) (TC 9.A.2) family.
messages: Membrane

230844:Atp8a1
gene id: 230844:Atp8a1
uniprot id: A0A6I9L105
uniprot id: A0A6I9L882
uniprot id: A0A6I9LBV5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.
messages: Membrane

230844:Tmem59l
gene id: 230844:Tmem59l
uniprot id: A0A6I9M2J3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM59 family.
messages: Golgi apparatus membrane
messages: Membrane

230844:Kdm6a
gene id: 230844:Kdm6a
uniprot id: A0A6I9M762
uniprot id: A0A6I9MDV9
uniprot id: A0A6I9MDW4
uniprot id: A0A6I9MHV3
uniprot id: A0A6I9MLC5
uniprot id: A0A6I9MLD0
uniprot id: A0A6I9MN13
uniprot id: A0A6I9MN16
uniprot id: A0A6J0CRM4
uniprot id: A0A6J0CRX8
uniprot id: A0A6J0CT58
uniprot id: A0A6J0CTS8
uniprot id: A0A6J0CW56
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UTX family.
messages: Nucleus

230844:Eomes
gene id: 230844:Eomes
uniprot id: A0A6I9KT64
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

230844:Dstn
gene id: 230844:Dstn
uniprot id: A0A6I9LX02
names: Similarity
messages: Belongs to the actin-binding proteins ADF family.

230844:St8sia2
gene id: 230844:St8sia2
uniprot id: A0A6I9M7C4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

230844:Dcp1a
gene id: 230844:Dcp1a
uniprot id: A0A6I9LN27
uniprot id: A0A6J0DI71
names: Similarity
messages: Belongs to the DCP1 family.

230844:Il1f10
gene id: 230844:Il1f10
uniprot id: A0A6I9LDY4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IL-1 family.
messages: Secreted

230844:Atad2
gene id: 230844:Atad2
uniprot id: A0A6I9M5I6
names: Similarity
messages: Belongs to the AAA ATPase family.

230844:Pdx1
gene id: 230844:Pdx1
uniprot id: A0A6I9LB06
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Antp homeobox family.
messages: Nucleus

230844:Tarbp2
gene id: 230844:Tarbp2
uniprot id: A0A6I9LFD2
uniprot id: A0A6J0DSS4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TARBP2 family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus
messages: Required for formation of the RNA induced silencing complex (RISC). Component of the RISC loading complex (RLC), also known as the micro-RNA (miRNA) loading complex (miRLC), which is composed of DICER1, AGO2 and TARBP2. Within the RLC/miRLC, DICER1 and TARBP2 are required to process precursor miRNAs (pre-miRNAs) to mature miRNAs and then load them onto AGO2. AGO2 bound to the mature miRNA constitutes the minimal RISC and may subsequently dissociate from DICER1 and TARBP2. May also play a role in the production of short interfering RNAs (siRNAs) from double-stranded RNA (dsRNA) by DICER1.
messages: Self-associates. Component of the RISC loading complex (RLC), or micro-RNA (miRNA) loading complex (miRLC), which is composed of DICER1, AGO2 and TARBP2. Note that the trimeric RLC/miRLC is also referred to as RISC. Interacts with EIF2AK2/PKR and inhibits its protein kinase activity. Interacts with DHX9 and PRKRA. Interacts with DICER1, AGO2, MOV10, EIF6 and RPL7A (60S ribosome subunit); they form a large RNA-induced silencing complex (RISC).
messages: perinuclear region

230844:Anxa7
gene id: 230844:Anxa7
uniprot id: A0A6I9LUI2
names: Domain
names: Similarity
messages: A pair of annexin repeats may form one binding site for calcium and phospholipid.
messages: Belongs to the annexin family.

230844:LOC102928146
gene id: 230844:LOC102928146
uniprot id: A0A6I9LTG6
names: Similarity
messages: Belongs to the WD repeat coronin family.

230844:Tmem151a
gene id: 230844:Tmem151a
uniprot id: A0A6I9LKB2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM151 family.
messages: Membrane

230844:Gpr75
gene id: 230844:Gpr75
uniprot id: A0A6J0CRT8
names: Subcellular Location Annotation
messages: Membrane

230844:Cops7b
gene id: 230844:Cops7b
uniprot id: A0A6I9LSE5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CSN7/EIF3M family. CSN7 subfamily.
messages: Component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF-type complexes such as SCF, CSA or DDB2. The complex is also involved in phosphorylation of p53/TP53, JUN, I-kappa-B-alpha/NFKBIA, ITPK1 and IRF8/ICSBP, possibly via its association with CK2 and PKD kinases. CSN-dependent phosphorylation of TP53 and JUN promotes and protects degradation by the Ubl system, respectively.
messages: Cytoplasm
messages: Nucleus

230844:Gabrg2
gene id: 230844:Gabrg2
uniprot id: A0A6I9KV26
uniprot id: A0A6I9L1L2
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family. Gamma-aminobutyric acid receptor (TC 1.A.9.5) subfamily. GABRG2 sub-subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

230844:LOC102903065
gene id: 230844:LOC102903065
uniprot id: A0A6I9KZQ0
names: Similarity
messages: Belongs to the cytochrome P450 family.

230844:Cpz
gene id: 230844:Cpz
uniprot id: A0A6I9LN66
names: Caution
names: Similarity
messages: Belongs to the peptidase M14 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

230844:Zscan22
gene id: 230844:Zscan22
uniprot id: A0A6I9MN81
names: Subcellular Location Annotation
messages: Nucleus

230844:Hnrnpc
gene id: 230844:Hnrnpc
uniprot id: A0A6I9LZT8
uniprot id: A0A6I9MFZ8
uniprot id: A0A6J0CGP2
uniprot id: A0A6J0CI47
uniprot id: A0A6J0CIR0
uniprot id: A0A6J0CL39
names: Similarity
messages: Belongs to the RRM HNRPC family. RALY subfamily.

230844:Fgfr3
gene id: 230844:Fgfr3
uniprot id: A0A6I9KXE4
uniprot id: A0A6I9KXN6
uniprot id: A0A6I9L7T7
uniprot id: A0A6J0CUV1
uniprot id: A0A6J0CWD9
uniprot id: A0A6J0CWE4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. Fibroblast growth factor receptor subfamily.
messages: Cell membrane
messages: Membrane

230844:Dph6
gene id: 230844:Dph6
uniprot id: A0A6I9LXB6
names: Function
names: Similarity
messages: Amidase that catalyzes the last step of diphthamide biosynthesis using ammonium and ATP.
messages: Belongs to the Diphthine--ammonia ligase family.

230844:Unc5b
gene id: 230844:Unc5b
uniprot id: A0A6I9KXA0
uniprot id: A0A6I9L452
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the unc-5 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for netrin required for axon guidance. Mediates axon repulsion of neuronal growth cones in the developing nervous system upon ligand binding.

230844:LOC102903692
gene id: 230844:LOC102903692
uniprot id: A0A6I9M5H4
names: Similarity
messages: Belongs to the CCSER family.

230844:Eva1c
gene id: 230844:Eva1c
uniprot id: A0A6I9LWR1
uniprot id: A0A6J0DNT0
uniprot id: A0A6J0DRV9
names: Similarity
messages: Belongs to the EVA1 family.

230844:Kng1
gene id: 230844:Kng1
uniprot id: A0A6I9LJK9
names: Subcellular Location Annotation
messages: extracellular space

230844:LOC102926484
gene id: 230844:LOC102926484
uniprot id: A0A6I9LBZ3
names: Similarity
messages: Belongs to the LCE family.

230844:Ist1
gene id: 230844:Ist1
uniprot id: A0A6I9KZU4
uniprot id: A0A6I9L720
uniprot id: A0A6I9LAP8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IST1 family.
messages: Cytoplasmic vesicle
messages: Nucleus envelope

230844:B3galnt1
gene id: 230844:B3galnt1
uniprot id: A0A6J0CV39
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane

230844:Slc4a1
gene id: 230844:Slc4a1
uniprot id: A0A6I9KT39
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anion exchanger (TC 2.A.31) family.
messages: Cell membrane
messages: Membrane

230844:S100a5
gene id: 230844:S100a5
uniprot id: A0A6I9LBI1
names: Similarity
messages: Belongs to the S-100 family.

230844:Fgd4
gene id: 230844:Fgd4
uniprot id: A0A6I9MA66
uniprot id: A0A6J0CJU2
names: Subcellular Location Annotation
messages: cytoskeleton

230844:Thpo
gene id: 230844:Thpo
uniprot id: A0A6J0E8C3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPO/TPO family.
messages: Secreted

230844:Qtrt2
gene id: 230844:Qtrt2
uniprot id: A0A6I9LAK2
uniprot id: A0A6J0D5Y9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family. QTRT2 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Heterodimer of a catalytic subunit QTRT1 and an accessory subunit QTRT2.
messages: Mitochondrion outer membrane
messages: Non-catalytic subunit of the queuine tRNA-ribosyltransferase (TGT) that catalyzes the base-exchange of a guanine (G) residue with queuine (Q) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).

230844:Nr3c1
gene id: 230844:Nr3c1
uniprot id: A0A6I9LCY2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR3 subfamily.
messages: Mitochondrion
messages: Nucleus
messages: centrosome
messages: spindle

230844:Adss1
gene id: 230844:Adss1
uniprot id: A0A6I9M0B0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Component of the purine nucleotide cycle (PNC), which interconverts IMP and AMP to regulate the nucleotide levels in various tissues, and which contributes to glycolysis and ammoniagenesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP.
messages: Component of the purine nucleotide cycle (PNC), which interconverts IMP and AMP to regulate the nucleotide levels in various tissues, and which contributes to glycolysis and ammoniagenesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis.

230844:St8sia5
gene id: 230844:St8sia5
uniprot id: A0A6I9KZ93
uniprot id: A0A6I9L6M3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

230844:Rpl36al
gene id: 230844:Rpl36al
uniprot id: A0A6I9LV84
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL42 family.

230844:Rrm2b
gene id: 230844:Rrm2b
uniprot id: A0A6I9LFL9
uniprot id: A0A6I9LVE8
names: Cofactor
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.
messages: Binds 2 iron ions per subunit.

230844:Kcnv1
gene id: 230844:Kcnv1
uniprot id: A0A6I9L7Q2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the potassium channel family. V (TC 1.A.1.2) subfamily. Kv8.1/KCNV1 sub-subfamily.
messages: Heteromultimer with KCNB1 and KCNB2. Interacts with KCNC4 and KCND1.
messages: Membrane
messages: Potassium channel subunit that does not form functional channels by itself. Modulates KCNB1 and KCNB2 channel activity by shifting the threshold for inactivation to more negative values and by slowing the rate of inactivation. Can down-regulate the channel activity of KCNB1, KCNB2, KCNC4 and KCND1, possibly by trapping them in intracellular membranes.

230844:Syngr1
gene id: 230844:Syngr1
uniprot id: A0A6I9L8L9
uniprot id: A0A6I9LI95
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptogyrin family.
messages: Membrane

230844:LOC102922186
gene id: 230844:LOC102922186
uniprot id: A0A6I9M5L0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protease inhibitor I39 (alpha-2-macroglobulin) family.
messages: Secreted

230844:Nt5dc3
gene id: 230844:Nt5dc3
uniprot id: A0A6I9LIM0
names: Cofactor
names: Similarity
messages: Belongs to the 5'(3')-deoxyribonucleotidase family.
messages: Binds 1 Mg(2+) ion per subunit.

230844:Sncg
gene id: 230844:Sncg
uniprot id: A0A6I9LGC4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the synuclein family.
messages: May be a centrosome-associated protein. Interacts with MYOC; affects its secretion and its aggregation.
messages: spindle

230844:Atg3
gene id: 230844:Atg3
uniprot id: A0A6I9LAM3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATG3 family.
messages: Cytoplasm

230844:Lin28a
gene id: 230844:Lin28a
uniprot id: A0A6I9LDY9
names: Similarity
messages: Belongs to the lin-28 family.

230844:St6gal1
gene id: 230844:St6gal1
uniprot id: A0A6J0E1F5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

230844:Lin7c
gene id: 230844:Lin7c
uniprot id: A0A6I9LQU3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Basolateral cell membrane
messages: Belongs to the lin-7 family.
messages: Cell membrane
messages: Lateral cell membrane
messages: Membrane
messages: Plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells.
messages: Postsynaptic density membrane
messages: tight junction

230844:Gdnf
gene id: 230844:Gdnf
uniprot id: A0A6I9LDC6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TGF-beta family. GDNF subfamily.
messages: Secreted

230844:Adra1a
gene id: 230844:Adra1a
uniprot id: A0A6J0E8G0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Cytoplasm
messages: Membrane
messages: Nucleus membrane
messages: caveola

230844:LOC102927790
gene id: 230844:LOC102927790
uniprot id: A0A6I9M2D9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Zdhhc15
gene id: 230844:Zdhhc15
uniprot id: A0A6I9LW66
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

230844:Pfdn4
gene id: 230844:Pfdn4
uniprot id: A0A6I9LJP7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the prefoldin subunit beta family.
messages: Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins.
messages: Heterohexamer of two PFD-alpha type and four PFD-beta type subunits.

230844:Csn1s1
gene id: 230844:Csn1s1
uniprot id: A0A6J0EEE8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alpha-casein family.
messages: Important role in the capacity of milk to transport calcium phosphate.
messages: Secreted

230844:Tada2a
gene id: 230844:Tada2a
uniprot id: A0A6I9LRH0
uniprot id: A0A6J0DWD2
names: Subcellular Location Annotation
messages: Nucleus

230844:Alg11
gene id: 230844:Alg11
uniprot id: A0A6I9MMT4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase group 1 family. Glycosyltransferase 4 subfamily.
messages: Endoplasmic reticulum membrane
messages: Required for N-linked oligosaccharide assembly.

230844:Ppp4r3a
gene id: 230844:Ppp4r3a
uniprot id: A0A6I9LWN4
uniprot id: A0A6I9MCW4
names: Similarity
messages: Belongs to the SMEK family.

230844:Lsr
gene id: 230844:Lsr
uniprot id: A0A6I9LE62
uniprot id: A0A6I9LTZ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the immunoglobulin superfamily. LISCH7 family.
messages: Membrane
messages: tight junction

230844:Cmbl
gene id: 230844:Cmbl
uniprot id: A0A6I9LIV0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dienelactone hydrolase family.
messages: cytosol

230844:Dusp7
gene id: 230844:Dusp7
uniprot id: A0A6I9LGF3
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.

230844:Washc3
gene id: 230844:Washc3
uniprot id: A0A6I9LBF5
uniprot id: A0A6I9LJS2
names: Similarity
messages: Belongs to the CCDC53 family.

230844:Tmem35b
gene id: 230844:Tmem35b
uniprot id: A0A6I9M0J9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DoxX family.
messages: Membrane

230844:Rfc5
gene id: 230844:Rfc5
uniprot id: A0A6I9L325
names: Similarity
messages: Belongs to the activator 1 small subunits family.

230844:Pdcl
gene id: 230844:Pdcl
uniprot id: A0A6J0CGN2
names: Similarity
messages: Belongs to the phosducin family.

230844:Cpa6
gene id: 230844:Cpa6
uniprot id: A0A6I9L132
names: Similarity
messages: Belongs to the peptidase M14 family.

230844:LOC102906724
gene id: 230844:LOC102906724
uniprot id: A0A6I9LEX3
names: Subcellular Location Annotation
messages: Nucleus

230844:LOC102920631
gene id: 230844:LOC102920631
uniprot id: A0A6I9LNN7
names: Similarity
messages: Belongs to the peptidase C1 family.

230844:LOC102917156
gene id: 230844:LOC102917156
uniprot id: A0A6I9LX73
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UDP-glycosyltransferase family.
messages: Membrane

230844:Glb1l2
gene id: 230844:Glb1l2
uniprot id: A0A6I9LC87
names: Similarity
messages: Belongs to the glycosyl hydrolase 35 family.

230844:LOC102919711
gene id: 230844:LOC102919711
uniprot id: A0A6I9LHL4
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phospholipase A2 family.
messages: Binds 1 Ca(2+) ion per subunit.
messages: Secreted

230844:Porcn
gene id: 230844:Porcn
uniprot id: A0A6I9M2H0
uniprot id: A0A6I9MA14
uniprot id: A0A6I9ME31
uniprot id: A0A6J0CME9
names: Subcellular Location Annotation
messages: Membrane

230844:LOC102916905
gene id: 230844:LOC102916905
uniprot id: A0A6I9MDX7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Sap18
gene id: 230844:Sap18
uniprot id: A0A6I9LUM9
names: Similarity
messages: Belongs to the SAP18 family.

230844:Hdx
gene id: 230844:Hdx
uniprot id: A0A6I9MDU5
uniprot id: A0A6I9MHT7
names: Subcellular Location Annotation
messages: Nucleus

230844:B3gnt3
gene id: 230844:B3gnt3
uniprot id: A0A6I9M852
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane

230844:LOC102917330
gene id: 230844:LOC102917330
uniprot id: A0A6I9MG99
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Naa35
gene id: 230844:Naa35
uniprot id: A0A6I9LNM9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Auxillary component of the N-terminal acetyltransferase C (NatC) complex which catalyzes acetylation of N-terminal methionine residues. Involved in regulation of apoptosis and proliferation of smooth muscle cells.
messages: Belongs to the MAK10 family.
messages: Component of the N-terminal acetyltransferase C (NatC) complex, which is composed of NAA35, NAA38 and NAA30.
messages: Cytoplasm

230844:Oprk1
gene id: 230844:Oprk1
uniprot id: A0A6J0CJG0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: G-protein coupled opioid receptor that functions as receptor for endogenous alpha-neoendorphins and dynorphins, but has low affinity for beta-endorphins. Also functions as receptor for various synthetic opioids and for the psychoactive diterpene salvinorin A. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling leads to the inhibition of adenylate cyclase activity. Inhibits neurotransmitter release by reducing calcium ion currents and increasing potassium ion conductance. Plays a role in the perception of pain. Plays a role in mediating reduced physical activity upon treatment with synthetic opioids. Plays a role in the regulation of salivation in response to synthetic opioids. May play a role in arousal and regulation of autonomic and neuroendocrine functions.
messages: Interacts with NHERF1. Interacts with GABARAPL1.
messages: Membrane

230844:Cisd2
gene id: 230844:Cisd2
uniprot id: A0A6I9KZ46
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CISD protein family. CISD2 subfamily.
messages: Binds 1 [2Fe-2S] cluster.
messages: Endoplasmic reticulum membrane
messages: Homodimer.
messages: Mitochondrion outer membrane
messages: Regulator of autophagy that contributes to antagonize BECN1-mediated cellular autophagy at the endoplasmic reticulum. Participates in the interaction of BCL2 with BECN1 and is required for BCL2-mediated depression of endoplasmic reticulum Ca(2+) stores during autophagy.

230844:LOC102920515
gene id: 230844:LOC102920515
uniprot id: A0A6I9MIR0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Esco1
gene id: 230844:Esco1
uniprot id: A0A6J0CKY5
names: Subcellular Location Annotation
messages: Nucleus

230844:Tspo2
gene id: 230844:Tspo2
uniprot id: A0A6J0CRI3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TspO/BZRP family.
messages: Membrane

230844:LOC102903806
gene id: 230844:LOC102903806
uniprot id: A0A6I9L9Q7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Rbfox2
gene id: 230844:Rbfox2
uniprot id: A0A6I9M3P2
uniprot id: A0A6I9MAZ3
uniprot id: A0A6I9MI41
uniprot id: A0A6I9MKC1
uniprot id: A0A6J0CN59
uniprot id: A0A6J0CN62
uniprot id: A0A6J0CN67
uniprot id: A0A6J0CNG4
uniprot id: A0A6J0CNG7
uniprot id: A0A6J0CNH1
uniprot id: A0A6J0CNH5
uniprot id: A0A6J0CPP1
uniprot id: A0A6J0CPP7
uniprot id: A0A6J0CQF5
uniprot id: A0A6J0CQF9
uniprot id: A0A6J0CQG3
uniprot id: A0A6J0CSF5
uniprot id: A0A6J0CSF9
uniprot id: A0A6J0CSG4
names: Function
names: Subcellular Location Annotation
messages: Nucleus
messages: RNA-binding protein that regulates alternative splicing events.

230844:Fxyd7
gene id: 230844:Fxyd7
uniprot id: A0A6I9LN64
uniprot id: A0A6J0DM43
names: Similarity
messages: Belongs to the FXYD family.

230844:Vps26a
gene id: 230844:Vps26a
uniprot id: A0A6I9KXB7
uniprot id: A0A6J0CS63
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VPS26 family.
messages: Endosome

230844:Vamp3
gene id: 230844:Vamp3
uniprot id: A0A6I9L9E8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptobrevin family.
messages: Membrane

230844:Fen1
gene id: 230844:Fen1
uniprot id: A0A6I9M0H9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the XPG/RAD2 endonuclease family. FEN1 subfamily.
messages: Binds 2 magnesium ions per subunit. They probably participate in the reaction catalyzed by the enzyme. May bind an additional third magnesium ion after substrate binding.
messages: Mitochondrion
messages: Structure-specific nuclease with 5'-flap endonuclease and 5'-3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site-terminated flap. Acts as a genome stabilization factor that prevents flaps from equilibrating into structures that lead to duplications and deletions. Also possesses 5'-3' exonuclease activity on nicked or gapped double-stranded DNA, and exhibits RNase H activity. Also involved in replication and repair of rDNA and in repairing mitochondrial DNA.
messages: nucleolus
messages: nucleoplasm

230844:Cnot2
gene id: 230844:Cnot2
uniprot id: A0A6I9M3U6
uniprot id: A0A6J0E3H3
names: Similarity
messages: Belongs to the CNOT2/3/5 family.

230844:Sub1
gene id: 230844:Sub1
uniprot id: A0A6I9LB99
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transcriptional coactivator PC4 family.
messages: General coactivator that functions cooperatively with TAFs and mediates functional interactions between upstream activators and the general transcriptional machinery. May be involved in stabilizing the multiprotein transcription complex. Binds single-stranded DNA. Also binds, in vitro, non-specifically to double-stranded DNA (ds DNA).
messages: Homodimer. Interacts with CSTF2.
messages: Nucleus

230844:LOC102916725
gene id: 230844:LOC102916725
uniprot id: A0A6J0CW62
names: Similarity
messages: Belongs to the serpin family.

230844:Plp2
gene id: 230844:Plp2
uniprot id: A0A6I9M2G0
names: Subcellular Location Annotation
messages: Membrane

230844:Tspan5
gene id: 230844:Tspan5
uniprot id: A0A6I9MK47
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

230844:Micos13
gene id: 230844:Micos13
uniprot id: A0A6I9LG75
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MICOS complex subunit Mic13 family.
messages: Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane.
messages: Component of the mitochondrial contact site and cristae organizing system (MICOS) complex.
messages: Membrane
messages: Mitochondrion inner membrane

230844:Gatm
gene id: 230844:Gatm
uniprot id: A0A6I9LS64
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the amidinotransferase family.
messages: Homodimer.
messages: Mitochondrion inner membrane
messages: Transamidinase that catalyzes the transfer of the amidino group of L-arginine onto the amino moiety of acceptor metabolites such as glycine, beta-alanine, gamma-aminobutyric acid (GABA) and taurine yielding the corresponding guanidine derivatives. Catalyzes the rate-limiting step of creatine biosynthesis, namely the transfer of the amidino group from L-arginine to glycine to generate guanidinoacetate, which is then methylated by GAMT to form creatine. Provides creatine as a source for ATP generation in tissues with high energy demands, in particular skeletal muscle, heart and brain.

230844:Sec62
gene id: 230844:Sec62
uniprot id: A0A6J0DMS8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEC62 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

230844:Cpne4
gene id: 230844:Cpne4
uniprot id: A0A6I9LWV5
uniprot id: A0A6J0DP21
uniprot id: A0A6J0DXJ1
names: Similarity
messages: Belongs to the copine family.

230844:Il4
gene id: 230844:Il4
uniprot id: A0A6I9MFL2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IL-4/IL-13 family.
messages: Participates in at least several B-cell activation processes as well as of other cell types. It is a costimulator of DNA-synthesis. It induces the expression of class II MHC molecules on resting B-cells. It enhances both secretion and cell surface expression of IgE and IgG1. It also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes.
messages: Secreted

230844:Rhcg
gene id: 230844:Rhcg
uniprot id: A0A6I9KY91
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonium transporter (TC 2.A.49) family. Rh subfamily.
messages: Membrane

230844:Nacc1
gene id: 230844:Nacc1
uniprot id: A0A6I9M525
names: Subcellular Location Annotation
messages: Nucleus

230844:Sstr3
gene id: 230844:Sstr3
uniprot id: A0A6I9L9Y2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

230844:Tll2
gene id: 230844:Tll2
uniprot id: A0A6I9M8W6
names: Caution
names: Cofactor
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

230844:Kiz
gene id: 230844:Kiz
uniprot id: A0A6I9LKN1
uniprot id: A0A6J0DZQ8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the kizuna family.
messages: Centrosomal protein required for establishing a robust mitotic centrosome architecture that can endure the forces that converge on the centrosomes during spindle formation. Required for stabilizing the expanded pericentriolar material around the centriole.
messages: centrosome
messages: cilium basal body

230844:Odf2
gene id: 230844:Odf2
uniprot id: A0A6J0DNE5
uniprot id: A0A6J0DQC6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ODF2 family.
messages: centrosome

230844:Med7
gene id: 230844:Med7
uniprot id: A0A6I9M241
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 7 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery.
messages: Component of the Mediator complex.
messages: Nucleus

230844:Ppp6r1
gene id: 230844:Ppp6r1
uniprot id: A0A6J0CCT4
names: Similarity
messages: Belongs to the SAPS family.

230844:LOC102907124
gene id: 230844:LOC102907124
uniprot id: A0A6J0CX18
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Ephb2
gene id: 230844:Ephb2
uniprot id: A0A6I9LLP8
uniprot id: A0A6J0DG42
uniprot id: A0A6J0DID1
uniprot id: A0A6J0DIH7
uniprot id: A0A6J0DP90
names: Subcellular Location Annotation
messages: Membrane

230844:LOC102927342
gene id: 230844:LOC102927342
uniprot id: A0A6I9LJE5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Cldn10
gene id: 230844:Cldn10
uniprot id: A0A6I9LGG5
uniprot id: A0A6I9LKT8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

230844:LOC102924989
gene id: 230844:LOC102924989
uniprot id: A0A6I9M242
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

230844:Tent5d
gene id: 230844:Tent5d
uniprot id: A0A6J0CDU2
names: Similarity
messages: Belongs to the TENT family.

230844:Setd7
gene id: 230844:Setd7
uniprot id: A0A6I9LEA4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. SET7 subfamily.
messages: Chromosome
messages: Histone methyltransferase that specifically monomethylates 'Lys-4' of histone H3. H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation. Plays a central role in the transcriptional activation of genes.
messages: Nucleus

230844:Lactb2
gene id: 230844:Lactb2
uniprot id: A0A6I9L8C0
names: Function
names: Similarity
messages: Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.
messages: Endoribonuclease; cleaves preferentially 3' to purine-pyrimidine dinucleotide motifs in single-stranded RNA. The cleavage product contains a free 3' -OH group. Has no activity with double-stranded RNA or DNA. Required for normal mitochondrial function and cell viability.

230844:LOC102913795
gene id: 230844:LOC102913795
uniprot id: A0A6I9MMW9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor T2R family.
messages: Membrane

230844:Papola
gene id: 230844:Papola
uniprot id: A0A6I9L1R8
uniprot id: A0A6I9L579
uniprot id: A0A6J0E2K8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the poly(A) polymerase family.
messages: Binds 2 magnesium ions. Also active with manganese.
messages: Nucleus
messages: Polymerase that creates the 3'-poly(A) tail of mRNA's.

230844:Csn3
gene id: 230844:Csn3
uniprot id: A0A6I9LWA9
uniprot id: A0A6J0EAK5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the kappa-casein family.
messages: Kappa-casein stabilizes micelle formation, preventing casein precipitation in milk.
messages: Secreted

230844:Cd2
gene id: 230844:Cd2
uniprot id: A0A6I9LW60
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

230844:Rab33a
gene id: 230844:Rab33a
uniprot id: A0A6I9MH13
names: Similarity
messages: Belongs to the small GTPase superfamily. Rab family.

230844:Tpd52
gene id: 230844:Tpd52
uniprot id: A0A6I9L7J0
uniprot id: A0A6I9LEX0
uniprot id: A0A6I9LFA1
uniprot id: A0A6J0DAG4
uniprot id: A0A6J0DB78
names: Similarity
messages: Belongs to the TPD52 family.

230844:LOC102926458
gene id: 230844:LOC102926458
uniprot id: A0A6I9LZD9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone H3 family.
messages: Belongs to the histone H4 family.
messages: Chromosome
messages: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
messages: Nucleus

230844:LOC102903901
gene id: 230844:LOC102903901
uniprot id: A0A6I9MNQ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Eef1e1
gene id: 230844:Eef1e1
uniprot id: A0A6I9KX90
names: Subcellular Location Annotation
messages: Cytoplasm

230844:Ttc36
gene id: 230844:Ttc36
uniprot id: A0A6I9M6D2
names: Similarity
messages: Belongs to the TTC36 family.

230844:Erh
gene id: 230844:Erh
uniprot id: A0A6I9KXT5
names: Function
names: Similarity
messages: Belongs to the E(R) family.
messages: May have a role in the cell cycle.

230844:LOC102905536
gene id: 230844:LOC102905536
uniprot id: A0A6I9L8A6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COX16 family.
messages: Membrane
messages: Mitochondrion inner membrane

230844:Pde8b
gene id: 230844:Pde8b
uniprot id: A0A6I9LDJ8
uniprot id: A0A6I9LT79
uniprot id: A0A6J0DIT2
uniprot id: A0A6J0DL69
uniprot id: A0A6J0DLE8
uniprot id: A0A6J0DSK2
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family.
messages: Belongs to the cyclic nucleotide phosphodiesterase family. PDE8 subfamily.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

230844:Slc35e4
gene id: 230844:Slc35e4
uniprot id: A0A6I9KXS4
names: Subcellular Location Annotation
messages: Membrane

230844:Naaladl1
gene id: 230844:Naaladl1
uniprot id: A0A6I9LQI2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M28 family. M28B subfamily.
messages: Cell membrane
messages: Membrane

230844:LOC102911293
gene id: 230844:LOC102911293
uniprot id: A0A6I9L990
names: Similarity
messages: Belongs to the peptidase A1 family.

230844:Il18
gene id: 230844:Il18
uniprot id: A0A6J0CIF4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IL-1 family.
messages: Cytoplasm
messages: Pro-inflammatory cytokine primarily involved in epithelial barrier repair, polarized T-helper 1 (Th1) cell and natural killer (NK) cell immune responses. Upon binding to IL18R1 and IL18RAP, forms a signaling ternary complex which activates NF-kappa-B, triggering synthesis of inflammatory mediators. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T-helper 1 (Th1) cells and natural killer (NK) cells. Involved in transduction of inflammation downstream of pyroptosis: its mature form is specifically released in the extracellular milieu by passing through the gasdermin-D (GSDMD) pore.
messages: Secreted

230844:LOC102922904
gene id: 230844:LOC102922904
uniprot id: A0A6I9LUY4
names: Similarity
messages: Belongs to the RGS7BP/RGS9BP family.

230844:Spin4
gene id: 230844:Spin4
uniprot id: A0A6J0DH86
names: Similarity
messages: Belongs to the SPIN/STSY family.

230844:LOC102912381
gene id: 230844:LOC102912381
uniprot id: A0A6I9LYW6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:B4galt4
gene id: 230844:B4galt4
uniprot id: A0A6I9L2F8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 7 family.
messages: Golgi apparatus membrane
messages: Membrane
messages: Responsible for the synthesis of complex-type N-linked oligosaccharides in many glycoproteins as well as the carbohydrate moieties of glycolipids.

230844:LOC102919307
gene id: 230844:LOC102919307
uniprot id: A0A6I9LNB0
names: Similarity
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. IRG family.

230844:LOC102924531
gene id: 230844:LOC102924531
uniprot id: A0A6J0CSX2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Rxfp1
gene id: 230844:Rxfp1
uniprot id: A0A6J0DGZ3
names: Caution
names: Subcellular Location Annotation
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

230844:Soat2
gene id: 230844:Soat2
uniprot id: A0A6I9LMR4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane-bound acyltransferase family. Sterol o-acyltransferase subfamily.
messages: Endoplasmic reticulum membrane
messages: Membrane

230844:LOC102906218
gene id: 230844:LOC102906218
uniprot id: A0A6I9LMH2
names: Similarity
messages: Belongs to the peptidase C1 family.

230844:LOC102907521
gene id: 230844:LOC102907521
uniprot id: A0A6I9ML75
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MHC class I family.
messages: Membrane

230844:LOC102923527
gene id: 230844:LOC102923527
uniprot id: A0A6I9LDH1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C1 family.
messages: Lysosome

230844:Dgki
gene id: 230844:Dgki
uniprot id: A0A6J0CT01
uniprot id: A0A6J0CVA7
names: Similarity
messages: Belongs to the eukaryotic diacylglycerol kinase family.

230844:Prlhr
gene id: 230844:Prlhr
uniprot id: A0A6I9LFZ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

230844:Actbl2
gene id: 230844:Actbl2
uniprot id: A0A6I9LD97
uniprot id: A0A6I9LNK9
names: Similarity
messages: Belongs to the actin family.

230844:LOC102911758
gene id: 230844:LOC102911758
uniprot id: A0A6I9LYC6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Hspa5
gene id: 230844:Hspa5
uniprot id: A0A6J0E4R1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heat shock protein 70 family.
messages: Cell surface
messages: Endoplasmic reticulum lumen
messages: Melanosome

230844:Rxrb
gene id: 230844:Rxrb
uniprot id: A0A6I9MDT8
uniprot id: A0A6I9MHT5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the nuclear hormone receptor family. NR2 subfamily.
messages: Composed of three domains: a modulating N-terminal domain, a DNA-binding domain and a C-terminal ligand-binding domain.
messages: Homodimer. Heterodimer; with a rar molecule.
messages: Nucleus
messages: Receptor for retinoic acid that acts as a transcription factor. Forms homo- or heterodimers with retinoic acid receptors (rars) and binds to target response elements in response to their ligands, all-trans or 9-cis retinoic acid, to regulate gene expression in various biological processes.

230844:Smpdl3a
gene id: 230844:Smpdl3a
uniprot id: A0A6I9LRW5
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acid sphingomyelinase family.
messages: Binds 2 Zn(2+) per subunit.
messages: Secreted

230844:Dock1
gene id: 230844:Dock1
uniprot id: A0A6I9LCY7
uniprot id: A0A6J0D960
names: Similarity
messages: Belongs to the DOCK family.

230844:Fus
gene id: 230844:Fus
uniprot id: A0A6I9L4P2
uniprot id: A0A6I9LD83
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRM TET family.
messages: Nucleus

230844:LOC102913468
gene id: 230844:LOC102913468
uniprot id: A0A6I9L9M0
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

230844:Kcnf1
gene id: 230844:Kcnf1
uniprot id: A0A6J0D639
names: Subcellular Location Annotation
messages: Membrane

230844:Tead1
gene id: 230844:Tead1
uniprot id: A0A6I9L7K3
uniprot id: A0A6I9L8Y1
uniprot id: A0A6I9LG80
uniprot id: A0A6I9LKJ5
uniprot id: A0A6J0DCL9
uniprot id: A0A6J0DDB7
uniprot id: A0A6J0DI21
names: Subcellular Location Annotation
messages: Nucleus

230844:Klhl15
gene id: 230844:Klhl15
uniprot id: A0A6J0E6B2
names: Subcellular Location Annotation
messages: Nucleus

230844:Pgr
gene id: 230844:Pgr
uniprot id: A0A6I9LSM8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Composed of three domains: a modulating N-terminal domain, a DNA-binding domain and a C-terminal ligand-binding domain.
messages: Cytoplasm
messages: Nucleus
messages: Steroid hormone receptor involved in the regulation of eukaryotic gene expression which affects cellular proliferation and differentiation in target tissues.

230844:Hsd17b3
gene id: 230844:Hsd17b3
uniprot id: A0A6I9LT50
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

230844:Nox3
gene id: 230844:Nox3
uniprot id: A0A6I9L7U6
names: Subcellular Location Annotation
messages: Membrane

230844:Smarca5
gene id: 230844:Smarca5
uniprot id: A0A6J0E8G5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNF2/RAD54 helicase family. ISWI subfamily.
messages: Nucleus

230844:Pou3f1
gene id: 230844:Pou3f1
uniprot id: A0A6I9LK46
names: Subcellular Location Annotation
messages: Nucleus

230844:Trub2
gene id: 230844:Trub2
uniprot id: A0A6I9LIH5
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family.

230844:Chsy1
gene id: 230844:Chsy1
uniprot id: A0A6J0D651
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chondroitin N-acetylgalactosaminyltransferase family.
messages: Golgi stack membrane
messages: Membrane

230844:Cdc25b
gene id: 230844:Cdc25b
uniprot id: A0A6I9LU16
uniprot id: A0A6J0DU87
names: Function
names: Similarity
messages: Belongs to the MPI phosphatase family.
messages: Functions as a dosage-dependent inducer in mitotic control. Tyrosine protein phosphatase required for progression of the cell cycle.

230844:Hsbp1
gene id: 230844:Hsbp1
uniprot id: A0A6I9M2E1
names: Similarity
messages: Belongs to the HSBP1 family.

230844:LOC102911120
gene id: 230844:LOC102911120
uniprot id: A0A6I9LN94
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:LOC102927050
gene id: 230844:LOC102927050
uniprot id: A0A6I9M5U6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PMG family.
messages: In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins.
messages: Interacts with hair keratins.

230844:Bcl9
gene id: 230844:Bcl9
uniprot id: A0A6I9LQD5
uniprot id: A0A6J0DL68
uniprot id: A0A6J0DNF1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BCL9 family.
messages: Nucleus

230844:Dnaaf1
gene id: 230844:Dnaaf1
uniprot id: A0A6I9LTN4
uniprot id: A0A6J0EA47
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNAAF1 family.
messages: Cilium-specific protein required for the stability of the ciliary architecture. Plays a role in cytoplasmic preassembly of dynein arms. Involved in regulation of microtubule-based cilia and actin-based brush border microvilli.
messages: cilium

230844:Smim19
gene id: 230844:Smim19
uniprot id: A0A6I9LG21
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SMIM19 family.
messages: Membrane

230844:LOC102913947
gene id: 230844:LOC102913947
uniprot id: A0A6I9LJV9
uniprot id: A0A6J0DTI2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BPI/LBP/Plunc superfamily. BPI/LBP family.
messages: Involved in the transfer of neutral lipids, including cholesteryl ester and triglyceride, among lipoprotein particles. Allows the net movement of cholesteryl ester from high density lipoproteins/HDL to triglyceride-rich very low density lipoproteins/VLDL, and the equimolar transport of triglyceride from VLDL to HDL.
messages: Secreted

230844:Trhde
gene id: 230844:Trhde
uniprot id: A0A6I9M3T5
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M1 family.
messages: Binds 1 zinc ion per subunit.

230844:LOC102905805
gene id: 230844:LOC102905805
uniprot id: A0A6I9LHI9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S1 family.
messages: Membrane

230844:Mat2a
gene id: 230844:Mat2a
uniprot id: A0A6J0CPA1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit. The potassium ion interacts primarily with the substrate.
messages: Binds 2 magnesium ions per subunit. The magnesium ions interact primarily with the substrate.
messages: Catalyzes the formation of S-adenosylmethionine from methionine and ATP.

230844:Hebp2
gene id: 230844:Hebp2
uniprot id: A0A6I9LWW1
names: Similarity
messages: Belongs to the HEBP family.

230844:Fam219a
gene id: 230844:Fam219a
uniprot id: A0A6I9LLB7
uniprot id: A0A6I9LWL6
uniprot id: A0A6J0DVT6
uniprot id: A0A6J0DX94
names: Similarity
messages: Belongs to the FAM219 family.

230844:Grin2c
gene id: 230844:Grin2c
uniprot id: A0A6I9MP47
uniprot id: A0A6J0CUH7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Receptor for glutamate that functions as a ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system.
messages: Synaptic cell membrane

230844:Gorasp2
gene id: 230844:Gorasp2
uniprot id: A0A6I9KWK8
names: Similarity
messages: Belongs to the GORASP family.

230844:Btg2
gene id: 230844:Btg2
uniprot id: A0A6I9LZH2
names: Similarity
messages: Belongs to the BTG family.

230844:Mrpl41
gene id: 230844:Mrpl41
uniprot id: A0A6I9LC68
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mL41 family.
messages: Mitochondrion

230844:Rftn2
gene id: 230844:Rftn2
uniprot id: A0A6J0D2T5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the raftlin family.
messages: Cell membrane
messages: Membrane

230844:LOC102923473
gene id: 230844:LOC102923473
uniprot id: A0A6I9MDZ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Crybg2
gene id: 230844:Crybg2
uniprot id: A0A6I9LAA6
uniprot id: A0A6J0D9C6
names: Similarity
messages: Belongs to the beta/gamma-crystallin family.

230844:Gchfr
gene id: 230844:Gchfr
uniprot id: A0A6I9LLW2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GFRP family.
messages: Membrane
messages: Nucleus membrane
messages: cytosol

230844:Hs3st2
gene id: 230844:Hs3st2
uniprot id: A0A6I9LKN9
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

230844:Mterf3
gene id: 230844:Mterf3
uniprot id: A0A6I9LEN4
names: Similarity
messages: Belongs to the mTERF family.

230844:LOC102906624
gene id: 230844:LOC102906624
uniprot id: A0A6I9LJ85
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M10A family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Can bind about 5 Ca(2+) ions per subunit.

230844:Hoxa2
gene id: 230844:Hoxa2
uniprot id: A0A6I9LEE5
names: Subcellular Location Annotation
messages: Nucleus

230844:Eef1a2
gene id: 230844:Eef1a2
uniprot id: A0A6I9MD74
names: Function
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

230844:LOC102922922
gene id: 230844:LOC102922922
uniprot id: A0A6I9LSU4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:LOC102924610
gene id: 230844:LOC102924610
uniprot id: A0A6I9M562
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2B family.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

230844:Arrdc5
gene id: 230844:Arrdc5
uniprot id: A0A6I9LUA9
names: Similarity
messages: Belongs to the arrestin family.

230844:LOC102922503
gene id: 230844:LOC102922503
uniprot id: A0A6I9M9D7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Bola2b
gene id: 230844:Bola2b
uniprot id: A0A6I9L4T7
names: Similarity
messages: Belongs to the BolA/IbaG family.

230844:Actn3
gene id: 230844:Actn3
uniprot id: A0A6I9LKA1
names: Similarity
messages: Belongs to the alpha-actinin family.

230844:LOC102910081
gene id: 230844:LOC102910081
uniprot id: A0A6I9MBA7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IFI6/IFI27 family.
messages: Membrane

230844:Nr1h3
gene id: 230844:Nr1h3
uniprot id: A0A6J0DR00
uniprot id: A0A6J0DSM3
uniprot id: A0A6J0DUD3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR1 subfamily.
messages: Nucleus

230844:Acap2
gene id: 230844:Acap2
uniprot id: A0A6I9L0F0
uniprot id: A0A6I9L7Y7
uniprot id: A0A6J0D017
uniprot id: A0A6J0D1K1
uniprot id: A0A6J0D298
uniprot id: A0A6J0D2A3
uniprot id: A0A6J0D5K9
names: Activity Regulation
names: Domain
names: Function
names: Subcellular Location Annotation
messages: Endosome membrane
messages: GAP activity stimulated by phosphatidylinositol 4,5-bisphosphate (PIP2) and phosphatidic acid.
messages: GTPase-activating protein for the ADP ribosylation factor family.
messages: PH domain binds phospholipids including phosphatidic acid, phosphatidylinositol 3-phosphate, phosphatidylinositol 3,5-bisphosphate (PIP2) and phosphatidylinositol 3,4,5-trisphosphate (PIP3). May mediate protein binding to PIP2 or PIP3 containing membranes.
messages: The BAR domain mediates homodimerization, it can neither bind membrane nor impart curvature, but instead requires the neighboring PH domain to achieve these functions.

230844:LOC102913796
gene id: 230844:LOC102913796
uniprot id: A0A6I9MLA2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MHC class II family.
messages: Membrane

230844:Orc6
gene id: 230844:Orc6
uniprot id: A0A6I9L1U9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ORC6 family.
messages: Nucleus

230844:Cilp2
gene id: 230844:Cilp2
uniprot id: A0A6I9MEW3
names: Subcellular Location Annotation
messages: extracellular matrix

230844:Ifnb1
gene id: 230844:Ifnb1
uniprot id: A0A6I9LES1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alpha/beta interferon family.
messages: Secreted

230844:Slc18a2
gene id: 230844:Slc18a2
uniprot id: A0A6J0DCY7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Vesicular transporter family.
messages: Membrane
messages: secretory vesicle membrane
messages: synaptic vesicle membrane

230844:Pcnx2
gene id: 230844:Pcnx2
uniprot id: A0A6I9LQ64
uniprot id: A0A6J0DNY2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pecanex family.
messages: Membrane

230844:E2f6
gene id: 230844:E2f6
uniprot id: A0A6I9L4V9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the E2F/DP family.
messages: Nucleus

230844:Samd8
gene id: 230844:Samd8
uniprot id: A0A6I9LLC2
uniprot id: A0A6I9LUE9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sphingomyelin synthase family.
messages: Membrane

230844:Sfxn1
gene id: 230844:Sfxn1
uniprot id: A0A6I9L5D4
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sideroflexin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Mitochondrion membrane

230844:Eif4ebp1
gene id: 230844:Eif4ebp1
uniprot id: A0A6I9MHX6
names: Similarity
messages: Belongs to the eIF4E-binding protein family.

230844:Maoa
gene id: 230844:Maoa
uniprot id: A0A6I9L5F7
names: Similarity
messages: Belongs to the flavin monoamine oxidase family.

230844:LOC102912653
gene id: 230844:LOC102912653
uniprot id: A0A6I9MGG7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:LOC102911269
gene id: 230844:LOC102911269
uniprot id: A0A6I9LCC2
names: Similarity
messages: Belongs to the cytochrome P450 family.

230844:Thg1l
gene id: 230844:Thg1l
uniprot id: A0A6I9M1P4
names: Cofactor
names: Function
names: Similarity
messages: Adds a GMP to the 5'-end of tRNA(His) after transcription and RNase P cleavage.
messages: Belongs to the tRNA(His) guanylyltransferase family.
messages: Binds 2 magnesium ions per subunit.

230844:Fscn1
gene id: 230844:Fscn1
uniprot id: A0A6I9LYA7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fascin family.
messages: cytoskeleton

230844:Caprin2
gene id: 230844:Caprin2
uniprot id: A0A6J0DXH0
uniprot id: A0A6J0E0I4
uniprot id: A0A6J0E5L5
names: Similarity
messages: Belongs to the caprin family.

230844:LOC102920322
gene id: 230844:LOC102920322
uniprot id: A0A6I9LF46
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C1 family.
messages: Lysosome

230844:Tjap1
gene id: 230844:Tjap1
uniprot id: A0A6I9LUU8
names: Subcellular Location Annotation
messages: Membrane

230844:Rpl26l1
gene id: 230844:Rpl26l1
uniprot id: A0A6J0DD63
names: Similarity
messages: Belongs to the universal ribosomal protein uL24 family.

230844:LOC102920694
gene id: 230844:LOC102920694
uniprot id: A0A6I9MB49
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mago nashi family.
messages: Nucleus

230844:LOC102920830
gene id: 230844:LOC102920830
uniprot id: A0A6J0DH62
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gasdermin family.
messages: Cell membrane
messages: Membrane
messages: cytosol

230844:Rpa1
gene id: 230844:Rpa1
uniprot id: A0A6I9L6G7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage.
messages: Belongs to the replication factor A protein 1 family.
messages: Component of the heterotrimeric canonical replication protein A complex (RPA).
messages: PML body

230844:Cdc42se2
gene id: 230844:Cdc42se2
uniprot id: A0A6I9LTV8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CDC42SE/SPEC family.
messages: Cell membrane
messages: Interacts with CDC42 (in GTP-bound form). Interacts weakly with RAC1 and not at all with RHOA.
messages: Membrane
messages: Probably involved in the organization of the actin cytoskeleton by acting downstream of CDC42, inducing actin filament assembly. Alters CDC42-induced cell shape changes. In activated T-cells, may play a role in CDC42-mediated F-actin accumulation at the immunological synapse. May play a role in early contractile events in phagocytosis in macrophages.
messages: cytoskeleton

230844:LOC102906231
gene id: 230844:LOC102906231
uniprot id: A0A6I9LMS2
names: Similarity
messages: Belongs to the type-B carboxylesterase/lipase family.

230844:Ninj2
gene id: 230844:Ninj2
uniprot id: A0A6J0CGF1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ninjurin family.
messages: Membrane

230844:Col4a2
gene id: 230844:Col4a2
uniprot id: A0A6I9LMT6
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Type IV collagen is the major structural component of glomerular basement membranes (GBM), forming a 'chicken-wire' meshwork together with laminins, proteoglycans and entactin/nidogen.
messages: basement membrane

230844:Esrrb
gene id: 230844:Esrrb
uniprot id: A0A6I9LTY1
uniprot id: A0A6I9M4S5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR3 subfamily.
messages: Nucleus

230844:Tnfaip1
gene id: 230844:Tnfaip1
uniprot id: A0A6I9LEC9
names: Similarity
messages: Belongs to the BACURD family.

230844:Tdo2
gene id: 230844:Tdo2
uniprot id: A0A6I9LK06
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tryptophan 2,3-dioxygenase family.
messages: Binds 1 heme group per subunit.
messages: Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L-tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety.
messages: Homotetramer. Dimer of dimers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

230844:Pheta2
gene id: 230844:Pheta2
uniprot id: A0A6J0DMP0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sesquipedalian family.
messages: Early endosome
messages: Forms homodimers and heterodimers with PHETA. Interacts with OCRL and INPP5B.
messages: Plays a role in endocytic trafficking. Required for receptor recycling from endosomes, both to the trans-Golgi network and the plasma membrane.
messages: Recycling endosome
messages: clathrin-coated vesicle
messages: trans-Golgi network

230844:LOC102906202
gene id: 230844:LOC102906202
uniprot id: A0A6I9MQM3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Dkk1
gene id: 230844:Dkk1
uniprot id: A0A6I9L3C6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dickkopf family.
messages: Secreted

230844:Klc1
gene id: 230844:Klc1
uniprot id: A0A6I9M1Y3
uniprot id: A0A6J0E104
uniprot id: A0A6J0E109
uniprot id: A0A6J0E114
uniprot id: A0A6J0E2S4
uniprot id: A0A6J0E2S7
uniprot id: A0A6J0E4A9
uniprot id: A0A6J0E5Y2
uniprot id: A0A6J0E5Y8
uniprot id: A0A6J0E5Z4
uniprot id: A0A6J0E8R8
uniprot id: A0A6J0E8S3
uniprot id: A0A6J0E8S7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the kinesin light chain family.
messages: Kinesin is a microtubule-associated force-producing protein that play a role in organelle transport.
messages: Oligomeric complex composed of two heavy chains and two light chains.
messages: cytoskeleton

230844:Nudt3
gene id: 230844:Nudt3
uniprot id: A0A6I9LVZ6
names: Similarity
messages: Belongs to the Nudix hydrolase family. DIPP subfamily.

230844:Lrrc51
gene id: 230844:Lrrc51
uniprot id: A0A6J0CJ25
names: Subcellular Location Annotation
messages: Cytoplasm

230844:Coq8a
gene id: 230844:Coq8a
uniprot id: A0A6I9L7C8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. ADCK protein kinase family.
messages: Membrane

230844:Smad7
gene id: 230844:Smad7
uniprot id: A0A6I9L9Z5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dwarfin/SMAD family.
messages: Cytoplasm
messages: Nucleus

230844:Uba1
gene id: 230844:Uba1
uniprot id: A0A6J0EBP5
names: Similarity
messages: Belongs to the ubiquitin-activating E1 family.

230844:Slc29a4
gene id: 230844:Slc29a4
uniprot id: A0A6I9M9E0
names: Similarity
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Belongs to the SLC29A/ENT transporter (TC 2.A.57) family.
messages: Membrane

230844:Qtrt1
gene id: 230844:Qtrt1
uniprot id: A0A6I9LRA9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Catalytic subunit of the queuine tRNA-ribosyltransferase (TGT) that catalyzes the base-exchange of a guanine (G) residue with queuine (Q) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming queuine, allowing a nucleophilic attack on the C1' of the ribose to form the product.
messages: Cytoplasm
messages: Heterodimer of a catalytic subunit QTRT1 and an accessory subunit QTRT2.
messages: Mitochondrion outer membrane

230844:Ccnd1
gene id: 230844:Ccnd1
uniprot id: A0A6I9LDR8
names: Similarity
messages: Belongs to the cyclin family.

230844:Sv2b
gene id: 230844:Sv2b
uniprot id: A0A6J0D948
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily.
messages: Membrane
messages: synaptic vesicle membrane

230844:Hps6
gene id: 230844:Hps6
uniprot id: A0A6I9M0M4
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Component of the biogenesis of lysosome-related organelles complex-2 (or BLOC2) composed of HPS3, HPS5 and HPS6. Interacts with HPS5 and HPS3. Interacts with biogenesis of lysosome-related organelles complex-1 (BLOC1). Interacts with AP-3 complex.
messages: May regulate the synthesis and function of lysosomes and of highly specialized organelles, such as melanosomes and platelet dense granules.
messages: Microsome membrane

230844:Odad4
gene id: 230844:Odad4
uniprot id: A0A6I9M9Y0
uniprot id: A0A6J0CHD1
names: Subcellular Location Annotation
messages: cilium axoneme

230844:Taf5l
gene id: 230844:Taf5l
uniprot id: A0A6I9LV60
uniprot id: A0A6J0ECF8
names: Similarity
messages: Belongs to the WD repeat TAF5 family.

230844:Bcl7b
gene id: 230844:Bcl7b
uniprot id: A0A6I9L179
names: Similarity
messages: Belongs to the BCL7 family.

230844:Cd8a
gene id: 230844:Cd8a
uniprot id: A0A6I9M0K9
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

230844:Prkab2
gene id: 230844:Prkab2
uniprot id: A0A6I9LP85
names: Function
names: Similarity
messages: Belongs to the 5'-AMP-activated protein kinase beta subunit family.
messages: Non-catalytic subunit of AMP-activated protein kinase (AMPK), an energy sensor protein kinase that plays a key role in regulating cellular energy metabolism. In response to reduction of intracellular ATP levels, AMPK activates energy-producing pathways and inhibits energy-consuming processes: inhibits protein, carbohydrate and lipid biosynthesis, as well as cell growth and proliferation. AMPK acts via direct phosphorylation of metabolic enzymes, and by longer-term effects via phosphorylation of transcription regulators. Also acts as a regulator of cellular polarity by remodeling the actin cytoskeleton; probably by indirectly activating myosin. Beta non-catalytic subunit acts as a scaffold on which the AMPK complex assembles, via its C-terminus that bridges alpha (PRKAA1 or PRKAA2) and gamma subunits (PRKAG1, PRKAG2 or PRKAG3).

230844:Mog
gene id: 230844:Mog
uniprot id: A0A6I9M4Q1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the immunoglobulin superfamily. BTN/MOG family.
messages: Homodimer.
messages: Membrane
messages: Minor component of the myelin sheath. May be involved in completion and/or maintenance of the myelin sheath and in cell-cell communication. Mediates homophilic cell-cell adhesion.

230844:Inmt
gene id: 230844:Inmt
uniprot id: A0A6I9M3I1
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. NNMT/PNMT/TEMT family.

230844:Strn3
gene id: 230844:Strn3
uniprot id: A0A6J0D899
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat striatin family.
messages: Binds calmodulin in a calcium dependent manner. May function as scaffolding or signaling protein.
messages: Membrane

230844:Cldn15
gene id: 230844:Cldn15
uniprot id: A0A6I9KUV9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

230844:Casq2
gene id: 230844:Casq2
uniprot id: A0A6I9LQQ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calsequestrin family.
messages: Calsequestrin is a high-capacity, moderate affinity, calcium-binding protein and thus acts as an internal calcium store in muscle.
messages: Sarcoplasmic reticulum lumen

230844:LOC102903000
gene id: 230844:LOC102903000
uniprot id: A0A6I9L8G4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Slc34a2
gene id: 230844:Slc34a2
uniprot id: A0A6J0D4Q5
names: Similarity
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Belongs to the SLC34A transporter family.
messages: Cell membrane
messages: Membrane

230844:LOC102914847
gene id: 230844:LOC102914847
uniprot id: A0A6I9LPI5
names: Similarity
messages: Belongs to the archaeal Rpo10/eukaryotic RPB10 RNA polymerase subunit family.

230844:LOC102906173
gene id: 230844:LOC102906173
uniprot id: A0A6I9L8Y7
uniprot id: A0A6I9LCL9
names: Similarity
messages: Belongs to the beta/gamma-crystallin family.

230844:Atp10d
gene id: 230844:Atp10d
uniprot id: A0A6I9LN44
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.
messages: Membrane

230844:Mto1
gene id: 230844:Mto1
uniprot id: A0A6I9MJ88
names: Function
names: Similarity
messages: Belongs to the MnmG family.
messages: Involved in the 5-carboxymethylaminomethyl modification (mnm(5)s(2)U34) of the wobble uridine base in mitochondrial tRNAs.

230844:Fahd1
gene id: 230844:Fahd1
uniprot id: A0A6I9L527
names: Similarity
messages: Belongs to the FAH family.

230844:Slc39a6
gene id: 230844:Slc39a6
uniprot id: A0A6I9LAD1
names: Subcellular Location Annotation
messages: Membrane

230844:Ube3d
gene id: 230844:Ube3d
uniprot id: A0A6I9LX21
names: Function
messages: E3 ubiquitin-protein ligase which accepts ubiquitin from specific E2 ubiquitin-conjugating enzymes, and transfers it to substrates, generally promoting their degradation by the proteasome.

230844:LOC102921318
gene id: 230844:LOC102921318
uniprot id: A0A6I9L5U8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

230844:Gsx2
gene id: 230844:Gsx2
uniprot id: A0A6I9LNA0
names: Subcellular Location Annotation
messages: Nucleus

230844:Prkaa2
gene id: 230844:Prkaa2
uniprot id: A0A6I9LNF6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. SNF1 subfamily.
messages: Cytoplasm
messages: Nucleus

230844:LOC102927216
gene id: 230844:LOC102927216
uniprot id: A0A6I9LHS7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Atg4d
gene id: 230844:Atg4d
uniprot id: A0A6I9LN53
uniprot id: A0A6I9M3R0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C54 family.
messages: Cysteine protease that plays a key role in autophagy by mediating both proteolytic activation and delipidation of ATG8 family proteins.
messages: Cytoplasm

230844:Opn1mw
gene id: 230844:Opn1mw
uniprot id: A0A6I9ME33
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 1 family. Opsin subfamily.
messages: Membrane
messages: Monomer. Homodimer. Homotetramer.
messages: Visual pigments are the light-absorbing molecules that mediate vision. They consist of an apoprotein, opsin, covalently linked to cis-retinal. May increase spectral sensitivity in dim light.

230844:Amelx
gene id: 230844:Amelx
uniprot id: A0A6I9M157
names: Similarity
messages: Belongs to the amelogenin family.

230844:Ap1s2
gene id: 230844:Ap1s2
uniprot id: A0A6I9L502
uniprot id: A0A6J0CX76
uniprot id: A0A6J0D1Q5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adaptor complexes small subunit family.
messages: Cytoplasmic vesicle membrane
messages: Golgi apparatus
messages: Membrane
messages: clathrin-coated pit

230844:Nap1l1
gene id: 230844:Nap1l1
uniprot id: A0A6I9L0J6
uniprot id: A0A6I9L7V7
uniprot id: A0A6J0CZV7
uniprot id: A0A6J0D0P8
names: Similarity
messages: Belongs to the nucleosome assembly protein (NAP) family.

230844:Crybb2
gene id: 230844:Crybb2
uniprot id: A0A6I9LI03
names: Similarity
messages: Belongs to the beta/gamma-crystallin family.

230844:Mtx2
gene id: 230844:Mtx2
uniprot id: A0A6I9KWW5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metaxin family.
messages: Membrane
messages: Mitochondrion outer membrane

230844:LOC102905849
gene id: 230844:LOC102905849
uniprot id: A0A6I9L9K9
uniprot id: A0A6J0CYG9
uniprot id: A0A6J0CZD5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:LOC102919262
gene id: 230844:LOC102919262
uniprot id: A0A6I9MDK5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Kcnk1
gene id: 230844:Kcnk1
uniprot id: A0A6I9LUT5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
messages: Cell membrane
messages: Cytoplasmic vesicle
messages: Endosome
messages: Membrane
messages: Perikaryon
messages: Recycling endosome
messages: Synaptic cell membrane
messages: Vesicle
messages: dendrite

230844:Id3
gene id: 230844:Id3
uniprot id: A0A6I9LLN9
names: Subcellular Location Annotation
messages: Nucleus

230844:Nono
gene id: 230844:Nono
uniprot id: A0A6I9LLC4
names: Subcellular Location Annotation
messages: Nucleus speckle

230844:Nkd2
gene id: 230844:Nkd2
uniprot id: A0A6I9LTD6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NKD family.
messages: Cell autonomous antagonist of the canonical Wnt signaling pathway.
messages: Cell membrane
messages: Cytoplasm

230844:Cab39
gene id: 230844:Cab39
uniprot id: A0A6J0DTE0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mo25 family.
messages: Component of a complex that binds and activates STK11/LKB1. In the complex, required to stabilize the interaction between CAB39/MO25 (CAB39/MO25alpha or CAB39L/MO25beta) and STK11/LKB1.
messages: Component of a trimeric complex composed of STK11/LKB1, STRAD (STRADA or STRADB) and CAB39/MO25 (CAB39/MO25alpha or CAB39L/MO25beta): the complex tethers STK11/LKB1 in the cytoplasm and stimulates its catalytic activity.

230844:LOC102928554
gene id: 230844:LOC102928554
uniprot id: A0A6I9L2D9
names: Similarity
messages: Belongs to the NDK family.

230844:Timm8a
gene id: 230844:Timm8a
uniprot id: A0A6I9LQ20
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the small Tim family.
messages: Heterohexamer.
messages: Mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space.
messages: Mitochondrion inner membrane
messages: The twin CX3C motif contains 4 conserved Cys residues that form 2 disulfide bonds in the mitochondrial intermembrane space.

230844:Ptgfr
gene id: 230844:Ptgfr
uniprot id: A0A6J0E4V4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Hsdl2
gene id: 230844:Hsdl2
uniprot id: A0A6I9M0Q2
names: Subcellular Location Annotation
messages: Peroxisome

230844:Pard6g
gene id: 230844:Pard6g
uniprot id: A0A6I9L6F4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAR6 family.
messages: Cytoplasm
messages: tight junction

230844:Hs6st2
gene id: 230844:Hs6st2
uniprot id: A0A6I9MAI4
uniprot id: A0A6I9MEM0
uniprot id: A0A6J0CRR3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 6-O-sulfation enzyme which catalyzes the transfer of sulfate from 3'-phosphoadenosine 5'-phosphosulfate (PAPS) to position 6 of the N-sulfoglucosamine residue (GlcNS) of heparan sulfate.
messages: Belongs to the sulfotransferase 6 family.
messages: Membrane

230844:Bcat1
gene id: 230844:Bcat1
uniprot id: A0A6I9LYH6
uniprot id: A0A6J0E9T8
uniprot id: A0A6J0EC10
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

230844:Gja8
gene id: 230844:Gja8
uniprot id: A0A6I9LV13
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family. Alpha-type (group II) subfamily.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

230844:Becn2
gene id: 230844:Becn2
uniprot id: A0A6I9MG37
names: Similarity
messages: Belongs to the beclin family.

230844:Wnt4
gene id: 230844:Wnt4
uniprot id: A0A6I9LKU9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

230844:LOC102907986
gene id: 230844:LOC102907986
uniprot id: A0A6J0DVT8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome P450 family.
messages: Cytochromes P450 are a group of heme-thiolate monooxygenases. They oxidize a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Microsome membrane

230844:Tfdp1
gene id: 230844:Tfdp1
uniprot id: A0A6I9LED2
uniprot id: A0A6J0DHF9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the E2F/DP family.
messages: Nucleus

230844:Maml1
gene id: 230844:Maml1
uniprot id: A0A6I9LRI3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mastermind family.
messages: Nucleus speckle

230844:Mtcp1
gene id: 230844:Mtcp1
uniprot id: A0A6I9MEN5
names: Similarity
messages: Belongs to the TCL1 family.

230844:LOC102921027
gene id: 230844:LOC102921027
uniprot id: A0A6I9MPL4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

230844:LOC102917942
gene id: 230844:LOC102917942
uniprot id: A0A6I9LG01
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AB hydrolase superfamily. Lipase family.
messages: Secreted

230844:Entpd7
gene id: 230844:Entpd7
uniprot id: A0A6I9LX28
names: Similarity
messages: Belongs to the GDA1/CD39 NTPase family.

230844:Copb2
gene id: 230844:Copb2
uniprot id: A0A6I9L1Z8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the WD repeat COPB2 family.
messages: COPI-coated vesicle membrane
messages: Golgi apparatus membrane
messages: Membrane
messages: Oligomeric complex that consists of at least the alpha, beta, beta', gamma, delta, epsilon and zeta subunits.
messages: The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. In mammals, the coatomer can only be recruited by membranes associated to ADP-ribosylation factors (ARFs), which are small GTP-binding proteins; the complex also influences the Golgi structural integrity, as well as the processing, activity, and endocytic recycling of LDL receptors.
messages: This coatomer complex protein, essential for Golgi budding and vesicular trafficking, is a selective binding protein (RACK) for protein kinase C, epsilon type. It binds to Golgi membranes in a GTP-dependent manner.

230844:Cstf1
gene id: 230844:Cstf1
uniprot id: A0A6I9LK45
names: Subcellular Location Annotation
messages: Nucleus

230844:Hoxd10
gene id: 230844:Hoxd10
uniprot id: A0A6I9KWW1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Abd-B homeobox family.
messages: Nucleus

230844:Psmg2
gene id: 230844:Psmg2
uniprot id: A0A6I9KYM5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PSMG2 family.
messages: Chaperone protein which promotes assembly of the 20S proteasome as part of a heterodimer with PSMG1.
messages: Forms a heterodimer with PSMG1.

230844:Naa38
gene id: 230844:Naa38
uniprot id: A0A6I9KYH4
names: Function
names: Similarity
names: Subunit
messages: Auxillary component of the N-terminal acetyltransferase C (NatC) complex which catalyzes acetylation of N-terminal methionine residues.
messages: Belongs to the snRNP Sm proteins family.
messages: Component of the N-terminal acetyltransferase C (NatC) complex, which is composed of NAA35, NAA38 and NAA30.

230844:LOC102924473
gene id: 230844:LOC102924473
uniprot id: A0A6I9M217
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome P450 family.
messages: Cytochromes P450 are a group of heme-thiolate monooxygenases.
messages: Endoplasmic reticulum membrane
messages: Microsome membrane

230844:Tek
gene id: 230844:Tek
uniprot id: A0A6I9KZL9
uniprot id: A0A6I9L6S5
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

230844:Riok3
gene id: 230844:Riok3
uniprot id: A0A6I9LSF2
names: Function
names: Similarity
messages: Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family.
messages: Involved in regulation of type I interferon (IFN)-dependent immune response which plays a critical role in the innate immune response against DNA and RNA viruses.

230844:Efemp1
gene id: 230844:Efemp1
uniprot id: A0A6J0CNP3
uniprot id: A0A6J0CRC4
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

230844:Atxn7l3
gene id: 230844:Atxn7l3
uniprot id: A0A6I9L2L2
uniprot id: A0A6J0D676
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SGF11 family.
messages: Component of some SAGA transcription coactivator-HAT complexes, at least composed of ATXN7, ATXN7L3, ENY2, GCN5L2, SUPT3H, TAF10, TRRAP and USP22. Within the SAGA complex, ENY2, ATXN7, ATXN7L3, and USP22 form an additional subcomplex of SAGA called the DUB module (deubiquitination module). Interacts directly with ENY2 and USP22.
messages: Component of the transcription regulatory histone acetylation (HAT) complex SAGA, a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates in a subcomplex that specifically deubiquitinates both histones H2A and H2B. The SAGA complex is recruited to specific gene promoters by activators such as MYC, where it is required for transcription. Required for nuclear receptor-mediated transactivation. Within the complex, it is required to recruit USP22 and ENY2 into the SAGA complex. Regulates H2B monoubiquitination (H2Bub1) levels. Affects subcellular distribution of ENY2, USP22 and ATXN7L3B.
messages: Nucleus
messages: The C-terminal SGF11-type zinc-finger domain together with the C-terminal catalytic domain of USP22 forms the 'catalytic lobe' of the SAGA deubiquitination module.
messages: The long N-terminal helix forms part of the 'assembly lobe' of the SAGA deubiquitination module.

230844:LOC102917291
gene id: 230844:LOC102917291
uniprot id: A0A6I9MEC3
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

230844:LOC102925067
gene id: 230844:LOC102925067
uniprot id: A0A6I9MQI4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the pancreatic ribonuclease family.
messages: Endonuclease that catalyzes the cleavage of RNA on the 3' side of pyrimidine nucleotides. Acts on single-stranded and double-stranded RNA.
messages: Monomer. Interacts with and forms tight 1:1 complexes with RNH1. Dimerization of two such complexes may occur. Interaction with RNH1 inhibits this protein.

230844:Slco6a1
gene id: 230844:Slco6a1
uniprot id: A0A6J0DYL8
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the organo anion transporter (TC 2.A.60) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

230844:Dusp6
gene id: 230844:Dusp6
uniprot id: A0A6I9LI43
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.

230844:Thap1
gene id: 230844:Thap1
uniprot id: A0A6J0DPR7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the THAP1 family.
messages: DNA-binding transcription regulator that regulates endothelial cell proliferation and G1/S cell-cycle progression. Specifically binds the 5'-[AT]NTNN[GT]GGCA[AGT]-3' core DNA sequence and acts by modulating expression of pRB-E2F cell-cycle target genes.
messages: Interacts with PAWR. Component of a THAP1/THAP3-HCFC1-OGT complex that contains, either THAP1 or THAP3, HCFC1 and OGT. Interacts with OGT. Interacts (via the HBM) with HCFC1 (via the Kelch-repeat domain); the interaction recruits HCFC1 to the RRM1 promoter.
messages: nucleoplasm

230844:LOC102905835
gene id: 230844:LOC102905835
uniprot id: A0A6I9M7I7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

230844:LOC102922819
gene id: 230844:LOC102922819
uniprot id: A0A6J0EI57
names: Similarity
messages: Belongs to the cytochrome P450 family.

230844:Pmm1
gene id: 230844:Pmm1
uniprot id: A0A6I9LAG7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic PMM family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the synthesis of the GDP-mannose and dolichol-phosphate-mannose required for a number of critical mannosyl transfer reactions.

230844:Unk
gene id: 230844:Unk
uniprot id: A0A6I9ME02
uniprot id: A0A6I9MGG3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the unkempt family.
messages: Cytoplasm

230844:Emc3
gene id: 230844:Emc3
uniprot id: A0A6I9MIK4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EMC3 family.
messages: Component of the ER membrane protein complex (EMC).
messages: Membrane

230844:LOC102913676
gene id: 230844:LOC102913676
uniprot id: A0A6I9M926
names: Similarity
messages: Belongs to the flavin monoamine oxidase family.

230844:LOC102916802
gene id: 230844:LOC102916802
uniprot id: A0A6J0CQ39
names: Similarity
messages: Belongs to the peptidase C14A family.

230844:Chga
gene id: 230844:Chga
uniprot id: A0A6J0E8M0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromogranin/secretogranin protein family.
messages: Secreted

230844:Lamb1
gene id: 230844:Lamb1
uniprot id: A0A6I9M4Q0
uniprot id: A0A6J0E8I2
uniprot id: A0A6J0EAQ1
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: basement membrane

230844:Rsph3
gene id: 230844:Rsph3
uniprot id: A0A6I9LFQ7
uniprot id: A0A6J0DAZ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the flagellar radial spoke RSP3 family.
messages: flagellum axoneme

230844:Far1
gene id: 230844:Far1
uniprot id: A0A6I9L8Y6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fatty acyl-CoA reductase family.
messages: Catalyzes the reduction of fatty acyl-CoA to fatty alcohols.
messages: Peroxisome membrane

230844:Qrsl1
gene id: 230844:Qrsl1
uniprot id: A0A6I9LH47
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in the mitochondria. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Mitochondrion
messages: Subunit of the heterotrimeric GatCAB amidotransferase (AdT) complex, composed of A (QRSL1), B (GATB) and C (GATC) subunits.

230844:Stat3
gene id: 230844:Stat3
uniprot id: A0A6I9M595
uniprot id: A0A6I9MCB3
uniprot id: A0A6I9MEZ9
uniprot id: A0A6J0CJI8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transcription factor STAT family.
messages: Cytoplasm
messages: Nucleus

230844:Hnrnph2
gene id: 230844:Hnrnph2
uniprot id: A0A6I9LXW3
names: Subcellular Location Annotation
messages: nucleoplasm

230844:Aco1
gene id: 230844:Aco1
uniprot id: A0A6I9L9P2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aconitase/IPM isomerase family.
messages: Cytoplasm

230844:LOC102925009
gene id: 230844:LOC102925009
uniprot id: A0A6I9LWF0
names: Similarity
messages: Belongs to the themis family.

230844:Osbpl6
gene id: 230844:Osbpl6
uniprot id: A0A6J0CQC9
names: Similarity
messages: Belongs to the OSBP family.

230844:LOC102903890
gene id: 230844:LOC102903890
uniprot id: A0A6J0CRQ4
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Component of the large ribosomal subunit.

230844:Rps12
gene id: 230844:Rps12
uniprot id: A0A6I9M318
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS12 family.

230844:LOC102906916
gene id: 230844:LOC102906916
uniprot id: A0A6I9MP18
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

230844:LOC102916550
gene id: 230844:LOC102916550
uniprot id: A0A6I9M934
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Ddx5
gene id: 230844:Ddx5
uniprot id: A0A6I9KTJ9
names: Similarity
messages: Belongs to the DEAD box helicase family. DDX5/DBP2 subfamily.

230844:LOC102910806
gene id: 230844:LOC102910806
uniprot id: A0A6I9KZC5
names: Subcellular Location Annotation
messages: Membrane

230844:Rgs4
gene id: 230844:Rgs4
uniprot id: A0A6I9MCI9
names: Function
messages: Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. Activity on G(z)-alpha is inhibited by phosphorylation of the G-protein. Activity on G(z)-alpha and G(i)-alpha-1 is inhibited by palmitoylation of the G-protein.

230844:Psenen
gene id: 230844:Psenen
uniprot id: A0A6I9LPC8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEN-2 family.
messages: Golgi stack membrane
messages: Membrane

230844:Fam133a
gene id: 230844:Fam133a
uniprot id: A0A6J0DYB6
names: Similarity
messages: Belongs to the FAM133 family.

230844:LOC102925031
gene id: 230844:LOC102925031
uniprot id: A0A6I9MGW5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Cyyr1
gene id: 230844:Cyyr1
uniprot id: A0A6I9M5T3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CYYR1 family.
messages: Membrane

230844:LOC102905720
gene id: 230844:LOC102905720
uniprot id: A0A6I9M3N2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Cnr1
gene id: 230844:Cnr1
uniprot id: A0A6I9L1P9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: G-protein coupled receptor for cannabinoids, including endocannabinoids (eCBs), such as N-arachidonoylethanolamide (also called anandamide or AEA) and 2-arachidonoylglycerol (2-AG). Signaling typically involves reduction in cyclic AMP.
messages: Interacts (via C-terminus) with CNRIP1.
messages: Membrane
messages: Mitochondrion outer membrane
messages: Presynapse
messages: Synapse
messages: axon

230844:Sf1
gene id: 230844:Sf1
uniprot id: A0A6I9LBH4
uniprot id: A0A6I9LD85
uniprot id: A0A6I9LD89
uniprot id: A0A6I9LKK0
uniprot id: A0A6I9LKK6
uniprot id: A0A6I9LLF3
uniprot id: A0A6I9LQJ9
uniprot id: A0A6J0DHZ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BBP/SF1 family.
messages: Necessary for the splicing of pre-mRNA. Has a role in the recognition of the branch site (5'-UACUAAC-3'), the pyrimidine tract and the 3'-splice site at the 3'-end of introns.
messages: Nucleus

230844:Mylk2
gene id: 230844:Mylk2
uniprot id: A0A6I9LMX8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family.
messages: Cytoplasm
messages: May interact with centrin.

230844:Rbl1
gene id: 230844:Rbl1
uniprot id: A0A6I9LXT5
uniprot id: A0A6J0DYV7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the retinoblastoma protein (RB) family.
messages: Nucleus

230844:LOC102919572
gene id: 230844:LOC102919572
uniprot id: A0A6I9MHJ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Cul7
gene id: 230844:Cul7
uniprot id: A0A6I9M5T7
uniprot id: A0A6J0EC19
uniprot id: A0A6J0EE71
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cullin family.
messages: Cytoplasm

230844:Nexmif
gene id: 230844:Nexmif
uniprot id: A0A6J0EE81
names: Subcellular Location Annotation
messages: Nucleus

230844:LOC102915703
gene id: 230844:LOC102915703
uniprot id: A0A6J0E6B3
names: Function
names: Similarity
messages: Belongs to the phospholipid scramblase family.
messages: May mediate accelerated ATP-independent bidirectional transbilayer migration of phospholipids upon binding calcium ions that results in a loss of phospholipid asymmetry in the plasma membrane.

230844:Pfn3
gene id: 230844:Pfn3
uniprot id: A0A6I9L5A3
names: Similarity
messages: Belongs to the profilin family.

230844:Fggy
gene id: 230844:Fggy
uniprot id: A0A6I9L6T0
uniprot id: A0A6J0CZI8
uniprot id: A0A6J0D0C5
uniprot id: A0A6J0D124
names: Similarity
messages: Belongs to the FGGY kinase family.

230844:Mtmr1
gene id: 230844:Mtmr1
uniprot id: A0A6I9KZF2
uniprot id: A0A6I9L6J5
uniprot id: A0A6I9L6T1
uniprot id: A0A6J0CYE6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily.
messages: Cytoplasm

230844:Tomm7
gene id: 230844:Tomm7
uniprot id: A0A6I9LRL2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Tom7 family.
messages: Membrane
messages: Mitochondrion outer membrane

230844:Jmjd1c
gene id: 230844:Jmjd1c
uniprot id: A0A6I9L7K0
uniprot id: A0A6J0CU77
uniprot id: A0A6J0CXB5
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the JHDM2 histone demethylase family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Histone demethylase that specifically demethylates 'Lys-9' of histone H3, thereby playing a central role in histone code.
messages: Leu-Xaa-Xaa-Leu-Leu (LXXLL) motifs are known to mediate the association with nuclear receptors.
messages: Nucleus
messages: The JmjC domain and the C6-type zinc-finger are required for the demethylation activity.

230844:Tatdn2
gene id: 230844:Tatdn2
uniprot id: A0A6I9MIK1
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. TatD-type hydrolase family.

230844:Tsnax
gene id: 230844:Tsnax
uniprot id: A0A6I9LYL1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the translin family.
messages: Nucleus

230844:Creg1
gene id: 230844:Creg1
uniprot id: A0A6I9M2A9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CREG family.
messages: Secreted

230844:LOC102902890
gene id: 230844:LOC102902890
uniprot id: A0A6I9MF29
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Syn1
gene id: 230844:Syn1
uniprot id: A0A6I9M1Q1
uniprot id: A0A6I9M890
names: Similarity
messages: Belongs to the synapsin family.

230844:LOC102923562
gene id: 230844:LOC102923562
uniprot id: A0A6I9M800
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

230844:Nkrf
gene id: 230844:Nkrf
uniprot id: A0A6I9MB92
names: Similarity
messages: Belongs to the CARF family.

230844:Sp4
gene id: 230844:Sp4
uniprot id: A0A6I9M6G6
names: Subcellular Location Annotation
messages: Nucleus

230844:Snx14
gene id: 230844:Snx14
uniprot id: A0A6I9LJ45
uniprot id: A0A6I9LRF8
names: Similarity
messages: Belongs to the sorting nexin family.

230844:Nxf5
gene id: 230844:Nxf5
uniprot id: A0A6J0CQ99
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NXF family.
messages: Cytoplasm

230844:Ccnh
gene id: 230844:Ccnh
uniprot id: A0A6I9MD24
names: Function
names: Similarity
names: Subunit
messages: Associates primarily with CDK7 and MAT1 to form the CAK complex. CAK can further associate with the core-TFIIH to form the TFIIH basal transcription factor.
messages: Belongs to the cyclin family. Cyclin C subfamily.
messages: Regulates CDK7, the catalytic subunit of the CDK-activating kinase (CAK) enzymatic complex. CAK activates the cyclin-associated kinases CDK1, CDK2, CDK4 and CDK6 by threonine phosphorylation. CAK complexed to the core-TFIIH basal transcription factor activates RNA polymerase II by serine phosphorylation of the repetitive C-terminal domain (CTD) of its large subunit (POLR2A), allowing its escape from the promoter and elongation of the transcripts. Involved in cell cycle control and in RNA transcription by RNA polymerase II. Its expression and activity are constant throughout the cell cycle.

230844:Slc35a2
gene id: 230844:Slc35a2
uniprot id: A0A6I9MEQ0
uniprot id: A0A6J0CU40
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleotide-sugar transporter family. SLC35A subfamily.
messages: Golgi apparatus membrane
messages: Membrane

230844:S1pr5
gene id: 230844:S1pr5
uniprot id: A0A6I9LRC0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:LOC102918368
gene id: 230844:LOC102918368
uniprot id: A0A6I9MFZ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Recql4
gene id: 230844:Recql4
uniprot id: A0A6I9M8H0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the helicase family. RecQ subfamily.
messages: Nucleus

230844:Epdr1
gene id: 230844:Epdr1
uniprot id: A0A6I9M233
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ependymin family.
messages: Binds anionic lipids and gangliosides at acidic pH.
messages: Lysosome lumen

230844:Fgf3
gene id: 230844:Fgf3
uniprot id: A0A6I9L6D6
names: Similarity
messages: Belongs to the heparin-binding growth factors family.

230844:Gal
gene id: 230844:Gal
uniprot id: A0A6I9LCQ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the galanin family.
messages: Secreted

230844:Rnase1
gene id: 230844:Rnase1
uniprot id: A0A6I9MNU2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the pancreatic ribonuclease family.
messages: Endonuclease that catalyzes the cleavage of RNA on the 3' side of pyrimidine nucleotides. Acts on single-stranded and double-stranded RNA.
messages: Monomer. Interacts with and forms tight 1:1 complexes with RNH1. Dimerization of two such complexes may occur. Interaction with RNH1 inhibits this protein.

230844:Syt16
gene id: 230844:Syt16
uniprot id: A0A6I9LYE9
uniprot id: A0A6J0CJ76
names: Similarity
messages: Belongs to the synaptotagmin family.

230844:Sgcz
gene id: 230844:Sgcz
uniprot id: A0A6I9KZI7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sarcoglycan beta/delta/gamma/zeta family.
messages: cytoskeleton
messages: sarcolemma

230844:Gfra4
gene id: 230844:Gfra4
uniprot id: A0A6J0DU55
names: Similarity
messages: Belongs to the GDNFR family.

230844:Ciao3
gene id: 230844:Ciao3
uniprot id: A0A6I9LHA5
uniprot id: A0A6J0DD97
uniprot id: A0A6J0DE01
names: Similarity
messages: Belongs to the NARF family.

230844:Vdr
gene id: 230844:Vdr
uniprot id: A0A6I9L077
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR1 subfamily.
messages: Cytoplasm
messages: Nucleus

230844:Sypl2
gene id: 230844:Sypl2
uniprot id: A0A6I9L963
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptophysin/synaptobrevin family.
messages: Membrane

230844:Cacul1
gene id: 230844:Cacul1
uniprot id: A0A6I9L8N3
uniprot id: A0A6I9LGL4
names: Similarity
messages: Belongs to the cullin family.

230844:LOC102904924
gene id: 230844:LOC102904924
uniprot id: A0A6J0CR98
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LicD transferase family.
messages: Golgi apparatus membrane

230844:Bag6
gene id: 230844:Bag6
uniprot id: A0A6I9M2U2
uniprot id: A0A6I9MAC8
uniprot id: A0A6I9MAD3
uniprot id: A0A6I9MEE9
uniprot id: A0A6I9MEF3
uniprot id: A0A6I9MHD2
uniprot id: A0A6I9MHE0
uniprot id: A0A6I9MJL2
uniprot id: A0A6J0CMR8
names: Function
names: Subcellular Location Annotation
messages: Nucleus
messages: Released extracellularly via exosomes, it is a ligand of the natural killer/NK cells receptor NCR3 and stimulates NK cells cytotoxicity. It may thereby trigger NK cells cytotoxicity against neighboring tumor cells and immature myeloid dendritic cells (DC).
messages: cytosol
messages: extracellular exosome

230844:Fshb
gene id: 230844:Fshb
uniprot id: A0A6I9LAS2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycoprotein hormones subunit beta family.
messages: Secreted

230844:LOC102905839
gene id: 230844:LOC102905839
uniprot id: A0A6I9MBM3
names: Subcellular Location Annotation
messages: Membrane

230844:Jph1
gene id: 230844:Jph1
uniprot id: A0A6I9L0R0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the junctophilin family.
messages: Cell membrane
messages: Endoplasmic reticulum membrane
messages: Junctophilins contribute to the formation of junctional membrane complexes (JMCs) which link the plasma membrane with the endoplasmic or sarcoplasmic reticulum in excitable cells. Provides a structural foundation for functional cross-talk between the cell surface and intracellular calcium release channels.
messages: Membrane

230844:Foxj3
gene id: 230844:Foxj3
uniprot id: A0A6J0CN52
names: Subcellular Location Annotation
messages: Nucleus

230844:Ubn2
gene id: 230844:Ubn2
uniprot id: A0A6J0ED38
names: Similarity
messages: Belongs to the ubinuclein family.

230844:LOC102920076
gene id: 230844:LOC102920076
uniprot id: A0A6I9MFP5
uniprot id: A0A6J0CJR2
uniprot id: A0A6J0CP73
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat HIR1 family.
messages: Nucleus
messages: Required for replication-independent chromatin assembly and for the periodic repression of histone gene transcription during the cell cycle.

230844:Tars1
gene id: 230844:Tars1
uniprot id: A0A6I9M5Y8
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.

230844:Icam1
gene id: 230844:Icam1
uniprot id: A0A6I9LYR6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the immunoglobulin superfamily. ICAM family.
messages: Membrane

230844:LOC102906763
gene id: 230844:LOC102906763
uniprot id: A0A6J0CHH9
names: Subcellular Location Annotation
messages: Membrane

230844:LOC102911209
gene id: 230844:LOC102911209
uniprot id: A0A6J0E389
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the krueppel C2H2-type zinc-finger protein family.
messages: Nucleus

230844:F5
gene id: 230844:F5
uniprot id: A0A6I9L0T5
names: Similarity
messages: Belongs to the multicopper oxidase family.

230844:Ccna2
gene id: 230844:Ccna2
uniprot id: A0A6I9M7T8
names: Similarity
messages: Belongs to the cyclin family. Cyclin AB subfamily.

230844:Stx4
gene id: 230844:Stx4
uniprot id: A0A6I9LD45
uniprot id: A0A6J0D749
names: Similarity
messages: Belongs to the syntaxin family.

230844:Mlst8
gene id: 230844:Mlst8
uniprot id: A0A6I9L9K2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the WD repeat LST8 family.
messages: Cytoplasm
messages: Part of the mammalian target of rapamycin complex 1 (mTORC1) which contains MTOR, MLST8, RPTOR, AKT1S1/PRAS40 and DEPTOR. mTORC1 binds to and is inhibited by FKBP12-rapamycin. Part of the mammalian target of rapamycin complex 2 (mTORC2) which contains MTOR, MLST8, PRR5, RICTOR, MAPKAP1 and DEPTOR. Contrary to mTORC1, mTORC2 does not bind to and is not sensitive to FKBP12-rapamycin. Interacts directly with MTOR and RPTOR. Interacts with RHEB. Interacts with MEAK7. Interacts with SIK3.
messages: Subunit of both mTORC1 and mTORC2, which regulates cell growth and survival in response to nutrient and hormonal signals. mTORC1 is activated in response to growth factors or amino acids. Growth factor-stimulated mTORC1 activation involves a AKT1-mediated phosphorylation of TSC1-TSC2, which leads to the activation of the RHEB GTPase that potently activates the protein kinase activity of mTORC1. Amino acid-signaling to mTORC1 requires its relocalization to the lysosomes mediated by the Ragulator complex and the Rag GTPases. Activated mTORC1 up-regulates protein synthesis by phosphorylating key regulators of mRNA translation and ribosome synthesis. mTORC1 phosphorylates EIF4EBP1 and releases it from inhibiting the elongation initiation factor 4E (eiF4E). mTORC1 phosphorylates and activates S6K1, which then promotes protein synthesis by phosphorylating PDCD4 and targeting it for degradation. Within mTORC1, LST8 interacts directly with MTOR and enhances its kinase activity. In nutrient-poor conditions, stabilizes the MTOR-RPTOR interaction and favors RPTOR-mediated inhibition of MTOR activity. mTORC2 is also activated by growth factors, but seems to be nutrient-insensitive. mTORC2 seems to function upstream of Rho GTPases to regulate the actin cytoskeleton, probably by activating one or more Rho-type guanine nucleotide exchange factors. mTORC2 promotes the serum-induced formation of stress-fibers or F-actin. mTORC2 plays a critical role in AKT1 phosphorylation, which may facilitate the phosphorylation of the activation loop of AKT1 by PDK1 which is a prerequisite for full activation. mTORC2 regulates the phosphorylation of SGK1. mTORC2 also modulates the phosphorylation of PRKCA.

230844:LOC102907661
gene id: 230844:LOC102907661
uniprot id: A0A6J0DIW9
uniprot id: A0A6J0DLW2
names: Similarity
messages: Belongs to the PP3/GlyCAM-1 family.

230844:Tspan11
gene id: 230844:Tspan11
uniprot id: A0A6I9M5M1
uniprot id: A0A6J0E5P3
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

230844:Clasp1
gene id: 230844:Clasp1
uniprot id: A0A6I9M9P0
uniprot id: A0A6I9MDQ1
uniprot id: A0A6I9MGL2
uniprot id: A0A6J0CL79
uniprot id: A0A6J0CL85
uniprot id: A0A6J0CLU3
uniprot id: A0A6J0CLU7
uniprot id: A0A6J0CLV2
uniprot id: A0A6J0CLV4
uniprot id: A0A6J0CMU2
uniprot id: A0A6J0CMV1
uniprot id: A0A6J0CMV6
uniprot id: A0A6J0CNF9
uniprot id: A0A6J0CNG3
uniprot id: A0A6J0CNG9
uniprot id: A0A6J0CQI5
uniprot id: A0A6J0CQJ2
uniprot id: A0A6J0CQJ7
uniprot id: A0A6J0CQK1
names: Subcellular Location Annotation
messages: kinetochore

230844:Eif6
gene id: 230844:Eif6
uniprot id: A0A6I9LQF6
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-6 family.
messages: Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. Behaves as a stimulatory translation initiation factor downstream insulin/growth factors. Is also involved in ribosome biogenesis. Associates with pre-60S subunits in the nucleus and is involved in its nuclear export. Cytoplasmic release of TIF6 from 60S subunits and nuclear relocalization is promoted by a RACK1 (RACK1)-dependent protein kinase C activity. In tissues responsive to insulin, controls fatty acid synthesis and glycolysis by exerting translational control of adipogenic transcription factors such as CEBPB, CEBPD and ATF4 that have G/C rich or uORF in their 5'UTR. Required for ROS-dependent megakaryocyte maturation and platelets formation, controls the expression of mitochondrial respiratory chain genes involved in reactive oxygen species (ROS) synthesis. Involved in miRNA-mediated gene silencing by the RNA-induced silencing complex (RISC). Required for both miRNA-mediated translational repression and miRNA-mediated cleavage of complementary mRNAs by RISC. Modulates cell cycle progression and global translation of pre-B cells, its activation seems to be rate-limiting in tumorigenesis and tumor growth.
messages: Cytoplasm
messages: Monomer. Associates with the 60S ribosomal subunit. Interacts with RACK1. Interacts with DICER1, AGO2, TARBP2, MOV10 and RPL7A; they form a large RNA-induced silencing complex (RISC).
messages: Phosphorylation at Ser-174 and Ser-175 promotes nuclear export.
messages: nucleolus

230844:Ercc5
gene id: 230844:Ercc5
uniprot id: A0A6I9MML4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the XPG/RAD2 endonuclease family. XPG subfamily.
messages: Nucleus

230844:Cacfd1
gene id: 230844:Cacfd1
uniprot id: A0A6I9M5U5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calcium channel flower family.
messages: Membrane

230844:Abat
gene id: 230844:Abat
uniprot id: A0A6I9M3B3
names: Similarity
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer; disulfide-linked.

230844:Actrt2
gene id: 230844:Actrt2
uniprot id: A0A6I9LJT4
names: Similarity
messages: Belongs to the actin family.

230844:Mars1
gene id: 230844:Mars1
uniprot id: A0A6I9L565
uniprot id: A0A6I9L8Q9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm

230844:Idh2
gene id: 230844:Idh2
uniprot id: A0A6I9KRW7
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Homodimer.

230844:Pex1
gene id: 230844:Pex1
uniprot id: A0A6I9LVM9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAA ATPase family.
messages: cytosol

230844:LOC102924497
gene id: 230844:LOC102924497
uniprot id: A0A6I9LYA2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Poll
gene id: 230844:Poll
uniprot id: A0A6I9LQA8
uniprot id: A0A6J0E3F8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-X family.
messages: DNA polymerase that functions in several pathways of DNA repair. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Also contributes to DNA double-strand break repair by non-homologous end joining and homologous recombination. Has both template-dependent and template-independent (terminal transferase) DNA polymerase activities. Has also a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity.
messages: Nucleus

230844:Tmem106c
gene id: 230844:Tmem106c
uniprot id: A0A6J0D230
names: Similarity
messages: Belongs to the TMEM106 family.

230844:LOC102924429
gene id: 230844:LOC102924429
uniprot id: A0A6I9MJN9
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phospholipase A2 family.
messages: Binds 1 Ca(2+) ion per subunit.
messages: Secreted

230844:Mettl26
gene id: 230844:Mettl26
uniprot id: A0A6I9LHB4
names: Similarity
messages: Belongs to the UPF0585 family.

230844:Tecrl
gene id: 230844:Tecrl
uniprot id: A0A6I9LWE7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the steroid 5-alpha reductase family.
messages: Membrane

230844:LOC102926070
gene id: 230844:LOC102926070
uniprot id: A0A6I9MEX4
uniprot id: A0A6I9MHA4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

230844:Lig4
gene id: 230844:Lig4
uniprot id: A0A6I9LCQ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP-dependent DNA ligase family.
messages: Nucleus

230844:Bid
gene id: 230844:Bid
uniprot id: A0A6J0EAH3
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Membrane
messages: Mitochondrion outer membrane

230844:Hgfac
gene id: 230844:Hgfac
uniprot id: A0A6I9LN60
uniprot id: A0A6J0DU98
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

230844:Ddx28
gene id: 230844:Ddx28
uniprot id: A0A6I9LYE7
names: Domain
names: Function
names: Similarity
messages: Belongs to the DEAD box helicase family.
messages: RNA helicase.
messages: The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.

230844:Ghitm
gene id: 230844:Ghitm
uniprot id: A0A6I9L510
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

230844:Sema4d
gene id: 230844:Sema4d
uniprot id: A0A6I9LCT4
uniprot id: A0A6J0D8Y5
names: Caution
names: Similarity
messages: Belongs to the semaphorin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

230844:Lca5
gene id: 230844:Lca5
uniprot id: A0A6J0DTU3
names: Similarity
messages: Belongs to the LCA5 family.

230844:LOC102905936
gene id: 230844:LOC102905936
uniprot id: A0A6I9LZ06
names: Similarity
messages: Belongs to the threonine aldolase family.

230844:Dph3
gene id: 230844:Dph3
uniprot id: A0A6I9LGF5
uniprot id: A0A6J0D6G2
names: Similarity
messages: Belongs to the DPH3 family.

230844:Sla2
gene id: 230844:Sla2
uniprot id: A0A6I9LXT7
names: Subcellular Location Annotation
messages: Cytoplasm

230844:Mrrf
gene id: 230844:Mrrf
uniprot id: A0A6I9MHF5
uniprot id: A0A6J0CRM6
names: Function
names: Similarity
messages: Belongs to the RRF family.
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

230844:Crabp1
gene id: 230844:Crabp1
uniprot id: A0A6I9L1I3
names: Similarity
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.

230844:Abt1
gene id: 230844:Abt1
uniprot id: A0A6I9LZF3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ESF2/ABP1 family.
messages: nucleolus

230844:Gsn
gene id: 230844:Gsn
uniprot id: A0A6I9LVC8
uniprot id: A0A6I9M1R9
uniprot id: A0A6J0E2Y3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the villin/gelsolin family.
messages: Binds to actin and to fibronectin. Identified in a complex composed of ACTA1, COBL, GSN and TMSB4X. Interacts with the inactive form of EIF2AK2/PKR.
messages: Calcium-regulated, actin-modulating protein that binds to the plus (or barbed) ends of actin monomers or filaments, preventing monomer exchange (end-blocking or capping). It can promote the assembly of monomers into filaments (nucleation) as well as sever filaments already formed. Plays a role in ciliogenesis.
messages: cytoskeleton

230844:Mid1
gene id: 230844:Mid1
uniprot id: A0A6I9MFD5
uniprot id: A0A6I9MHR8
names: Subcellular Location Annotation
messages: cytoskeleton

230844:Rpa4
gene id: 230844:Rpa4
uniprot id: A0A6J0DZY3
names: Similarity
messages: Belongs to the replication factor A protein 2 family.

230844:Atrx
gene id: 230844:Atrx
uniprot id: A0A6I9LY70
uniprot id: A0A6I9M4L7
uniprot id: A0A6I9M997
uniprot id: A0A6I9MEE7
uniprot id: A0A6J0CGU6
names: Subcellular Location Annotation
messages: Nucleus
messages: telomere

230844:Rad9b
gene id: 230844:Rad9b
uniprot id: A0A6I9KU64
names: Similarity
messages: Belongs to the rad9 family.

230844:Lypd2
gene id: 230844:Lypd2
uniprot id: A0A6I9M898
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

230844:Rpl13
gene id: 230844:Rpl13
uniprot id: A0A6I9LNU4
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL13 family.

230844:LOC102905941
gene id: 230844:LOC102905941
uniprot id: A0A6I9M6G3
names: Similarity
messages: Belongs to the cytochrome P450 family.

230844:Vat1l
gene id: 230844:Vat1l
uniprot id: A0A6I9KZR7
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily.

230844:Top1mt
gene id: 230844:Top1mt
uniprot id: A0A6I9M4A6
names: Function
names: Similarity
messages: Belongs to the type IB topoisomerase family.
messages: Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus removing DNA supercoils. Finally, in the religation step, the DNA 5'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

230844:Ramp3
gene id: 230844:Ramp3
uniprot id: A0A6I9L4N4
names: Similarity
messages: Belongs to the RAMP family.

230844:Gcnt1
gene id: 230844:Gcnt1
uniprot id: A0A6J0CP68
names: Subcellular Location Annotation
messages: Golgi apparatus membrane
messages: Membrane

230844:LOC102915097
gene id: 230844:LOC102915097
uniprot id: A0A6J0EA61
names: Similarity
messages: Belongs to the serpin family.

230844:LOC102919428
gene id: 230844:LOC102919428
uniprot id: A0A6I9LSZ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:St8sia4
gene id: 230844:St8sia4
uniprot id: A0A6I9LNI0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

230844:Drd4
gene id: 230844:Drd4
uniprot id: A0A6I9L650
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Sycp3
gene id: 230844:Sycp3
uniprot id: A0A6J0DGK6
names: Similarity
messages: Belongs to the XLR/SYCP3 family.

230844:LOC102918151
gene id: 230844:LOC102918151
uniprot id: A0A6I9MH71
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Npb
gene id: 230844:Npb
uniprot id: A0A6I9LT20
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the neuropeptide B/W family.
messages: Secreted

230844:LOC102905507
gene id: 230844:LOC102905507
uniprot id: A0A6I9LW33
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GST superfamily. Alpha family.
messages: Cytoplasm

230844:Get1
gene id: 230844:Get1
uniprot id: A0A6I9LCR8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WRB/GET1 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

230844:Chst4
gene id: 230844:Chst4
uniprot id: A0A6I9KZX1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 1 family. Gal/GlcNAc/GalNAc subfamily.
messages: Membrane

230844:LOC102916006
gene id: 230844:LOC102916006
uniprot id: A0A6I9LJG1
names: Subcellular Location Annotation
messages: Secreted

230844:Mmd
gene id: 230844:Mmd
uniprot id: A0A6I9KW48
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ADIPOR family.
messages: Membrane

230844:Slc10a1
gene id: 230844:Slc10a1
uniprot id: A0A6J0CYG7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bile acid:sodium symporter (BASS) (TC 2.A.28) family.
messages: Membrane

230844:Jpt1
gene id: 230844:Jpt1
uniprot id: A0A6I9MGE9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the JUPITER family.
messages: Cytoplasm
messages: Nucleus

230844:Lyrm7
gene id: 230844:Lyrm7
uniprot id: A0A6I9LLL5
uniprot id: A0A6J0DSS2
uniprot id: A0A6J0E107
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Assembly factor required for Rieske Fe-S protein UQCRFS1 incorporation into the cytochrome b-c1 (CIII) complex. Functions as a chaperone, binding to this subunit within the mitochondrial matrix and stabilizing it prior to its translocation and insertion into the late CIII dimeric intermediate within the mitochondrial inner membrane.
messages: Belongs to the complex I LYR family.
messages: Interacts with UQCRFS1.
messages: Mitochondrion matrix

230844:LOC102925011
gene id: 230844:LOC102925011
uniprot id: A0A6I9M9F4
names: Similarity
messages: Belongs to the apolipoprotein L family.

230844:Pemt
gene id: 230844:Pemt
uniprot id: A0A6I9KYT9
uniprot id: A0A6J0CZY0
uniprot id: A0A6J0D310
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class VI-like SAM-binding methyltransferase superfamily. PEMT/PEM2 methyltransferase family.
messages: Catalyzes the three sequential steps of the methylation pathway for the biosynthesis of phosphatidylcholine, a critical and essential component for membrane structure. Uses S-adenosylmethionine (S-adenosyl-L-methionine, SAM or AdoMet) as the methyl group donor for the methylation of phosphatidylethanolamine (1,2-diacyl-sn-glycero-3-phosphoethanolamine, PE) to phosphatidylmonomethylethanolamine (1,2-diacyl-sn-glycero-3-phospho-N-methylethanolamine, PMME), PMME to phosphatidyldimethylethanolamine (1,2-diacyl-sn-glycero-3-phospho-N,N-dimethylethanolamine, PDME), and PDME to phosphatidylcholine (1,2-diacyl-sn-glycero-3-phosphocholine, PC), producing S-adenosyl-L-homocysteine in each step.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Mitochondrion membrane

230844:LOC102904487
gene id: 230844:LOC102904487
uniprot id: A0A6I9LSW6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Ddx47
gene id: 230844:Ddx47
uniprot id: A0A6I9L3U0
names: Similarity
messages: Belongs to the DEAD box helicase family. DDX47/RRP3 subfamily.

230844:Rusf1
gene id: 230844:Rusf1
uniprot id: A0A6I9LD73
uniprot id: A0A6J0D743
names: Similarity
messages: Belongs to the RUS1 family.

230844:Dnajc16
gene id: 230844:Dnajc16
uniprot id: A0A6J0D3T9
names: Function
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Plays an important role in regulating the size of autophagosomes during the formation process.

230844:Tmco3
gene id: 230844:Tmco3
uniprot id: A0A6I9LCM4
uniprot id: A0A6I9LRZ2
names: Subcellular Location Annotation
messages: Membrane

230844:Tgfb1i1
gene id: 230844:Tgfb1i1
uniprot id: A0A6I9L4N2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the paxillin family.
messages: Functions as a molecular adapter coordinating multiple protein-protein interactions at the focal adhesion complex and in the nucleus. Links various intracellular signaling modules to plasma membrane receptors and regulates the Wnt and TGFB signaling pathways.
messages: Nucleus matrix
messages: The LD (leucine and aspartate-rich) motif 3 mediates interaction with GIT1 and functions as a nuclear export signal.
messages: cytoskeleton
messages: focal adhesion

230844:Palm3
gene id: 230844:Palm3
uniprot id: A0A6I9MFB4
uniprot id: A0A6J0CHA7
names: Similarity
messages: Belongs to the paralemmin family.

230844:Opn4
gene id: 230844:Opn4
uniprot id: A0A6I9LCJ4
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Opsin subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

230844:Brix1
gene id: 230844:Brix1
uniprot id: A0A6I9M6V3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BRX1 family.
messages: Required for biogenesis of the 60S ribosomal subunit.
messages: nucleolus

230844:Rsl24d1
gene id: 230844:Rsl24d1
uniprot id: A0A6I9L681
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL24 family.

230844:Bpi
gene id: 230844:Bpi
uniprot id: A0A6J0DJV1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BPI/LBP/Plunc superfamily. BPI/LBP family.
messages: Monomer. Homodimer; disulfide-linked.
messages: Secreted
messages: The N- and C-terminal barrels adopt an identical fold despite having only 13% of conserved residues.
messages: The N-terminal region may be exposed to the interior of the granule, whereas the C-terminal portion may be embedded in the membrane. During phagocytosis and degranulation, proteases may be released and activated and cleave BPI at the junction of the N- and C-terminal portions of the molecule, providing controlled release of the N-terminal antibacterial fragment when bacteria are ingested.
messages: The cytotoxic action of BPI is limited to many species of Gram-negative bacteria; this specificity may be explained by a strong affinity of the very basic N-terminal half for the negatively charged lipopolysaccharides that are unique to the Gram-negative bacterial outer envelope.

230844:Slc12a8
gene id: 230844:Slc12a8
uniprot id: A0A6J0D1H7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC12A transporter family.
messages: Membrane

230844:LOC102913696
gene id: 230844:LOC102913696
uniprot id: A0A6I9M7T2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MHC class II family.
messages: Membrane

230844:Gk2
gene id: 230844:Gk2
uniprot id: A0A6I9L9R8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FGGY kinase family.
messages: Cytoplasm

230844:LOC102925491
gene id: 230844:LOC102925491
uniprot id: A0A6J0DMU9
uniprot id: A0A6J0DNL6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

230844:LOC102918984
gene id: 230844:LOC102918984
uniprot id: A0A6J0DD76
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane
messages: Mitochondrion inner membrane

230844:Prss12
gene id: 230844:Prss12
uniprot id: A0A6I9M2T2
names: Caution
names: Function
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays a role in neuronal plasticity and the proteolytic action may subserve structural reorganizations associated with learning and memory operations.
messages: Secreted

230844:LOC102914841
gene id: 230844:LOC102914841
uniprot id: A0A6I9MQB5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Oosp2
gene id: 230844:Oosp2
uniprot id: A0A6I9M8Q6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PLAC1 family.
messages: Secreted

230844:LOC102924198
gene id: 230844:LOC102924198
uniprot id: A0A6I9LBE1
names: Subcellular Location Annotation
messages: Membrane

230844:Septin9
gene id: 230844:Septin9
uniprot id: A0A6I9M4N5
uniprot id: A0A6J0E6R8
uniprot id: A0A6J0ECQ6
uniprot id: A0A6J0EE73
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.

230844:Fgb
gene id: 230844:Fgb
uniprot id: A0A6I9LVF6
names: Subcellular Location Annotation
names: Subunit
messages: Heterohexamer; disulfide linked. Contains 2 sets of 3 non-identical chains (alpha, beta and gamma). The 2 heterotrimers are in head to head conformation with the N-termini in a small central domain.
messages: Secreted

230844:LOC102925010
gene id: 230844:LOC102925010
uniprot id: A0A6J0ECI2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Myt1l
gene id: 230844:Myt1l
uniprot id: A0A6I9LT30
uniprot id: A0A6I9M3U1
uniprot id: A0A6J0E5F7
uniprot id: A0A6J0E7B2
uniprot id: A0A6J0E914
uniprot id: A0A6J0EBA0
uniprot id: A0A6J0ECU8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MYT1 family.
messages: Nucleus

230844:Cept1
gene id: 230844:Cept1
uniprot id: A0A6I9M9J6
uniprot id: A0A6J0CMN3
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

230844:Trmt61a
gene id: 230844:Trmt61a
uniprot id: A0A6I9M1X8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TRM61 family.
messages: Catalytic subunit of tRNA (adenine-N(1)-)-methyltransferase, which catalyzes the formation of N(1)-methyladenine at position 58 (m1A58) in initiator methionyl-tRNA.
messages: Nucleus

230844:Ubap2l
gene id: 230844:Ubap2l
uniprot id: A0A6I9LBM7
uniprot id: A0A6I9LFG2
uniprot id: A0A6J0D557
uniprot id: A0A6J0D562
uniprot id: A0A6J0D567
uniprot id: A0A6J0D6A6
uniprot id: A0A6J0D6B3
uniprot id: A0A6J0D6B8
uniprot id: A0A6J0D6V1
uniprot id: A0A6J0D6V7
uniprot id: A0A6J0D6W2
uniprot id: A0A6J0D7C9
uniprot id: A0A6J0D7D4
uniprot id: A0A6J0D7D9
uniprot id: A0A6J0DBC1
uniprot id: A0A6J0DBC6
uniprot id: A0A6J0DBD1
names: Subcellular Location Annotation
messages: Cytoplasm

230844:Tmem11
gene id: 230844:Tmem11
uniprot id: A0A6I9KYY0
uniprot id: A0A6J0D2X9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM11 family.
messages: Membrane
messages: Plays a role in mitochondrial morphogenesis.

230844:Tsc22d4
gene id: 230844:Tsc22d4
uniprot id: A0A6I9L113
names: Similarity
messages: Belongs to the TSC-22/Dip/Bun family.

230844:LOC102904157
gene id: 230844:LOC102904157
uniprot id: A0A6I9M4K7
uniprot id: A0A6J0E491
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

230844:LOC102912698
gene id: 230844:LOC102912698
uniprot id: A0A6I9LN97
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Tmem121
gene id: 230844:Tmem121
uniprot id: A0A6J0E4I2
names: Similarity
messages: Belongs to the TMEM121 family.

230844:Cyria
gene id: 230844:Cyria
uniprot id: A0A6I9LG28
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CYRI family.
messages: Interacts with RAC1 (GTP-bound form preferentially).
messages: Membrane

230844:Crem
gene id: 230844:Crem
uniprot id: A0A6I9LXG5
uniprot id: A0A6I9M3I0
uniprot id: A0A6I9M3I5
uniprot id: A0A6I9M8E2
uniprot id: A0A6I9M9Y5
uniprot id: A0A6I9MDK1
uniprot id: A0A6J0CDD8
uniprot id: A0A6J0CDE6
uniprot id: A0A6J0CDF1
uniprot id: A0A6J0CF30
uniprot id: A0A6J0CF35
uniprot id: A0A6J0CFH1
uniprot id: A0A6J0CFH9
uniprot id: A0A6J0CG54
uniprot id: A0A6J0CHE7
uniprot id: A0A6J0CHF2
names: Subcellular Location Annotation
messages: Nucleus

230844:LOC102914213
gene id: 230844:LOC102914213
uniprot id: A0A6I9MF09
names: Similarity
messages: Belongs to the cytochrome P450 family.

230844:Nadsyn1
gene id: 230844:Nadsyn1
uniprot id: A0A6I9LDQ5
uniprot id: A0A6J0DE96
names: Similarity
names: Subunit
messages: Homohexamer.
messages: In the C-terminal section; belongs to the NAD synthetase family.

230844:Fgf21
gene id: 230844:Fgf21
uniprot id: A0A6I9LTP4
names: Similarity
messages: Belongs to the heparin-binding growth factors family.

230844:Dnah10
gene id: 230844:Dnah10
uniprot id: A0A6I9KZM0
names: Similarity
messages: Belongs to the dynein heavy chain family.

230844:Ccdc34
gene id: 230844:Ccdc34
uniprot id: A0A6I9LBP7
names: Subcellular Location Annotation
messages: flagellum

230844:Uroc1
gene id: 230844:Uroc1
uniprot id: A0A6I9M3Z6
names: Similarity
messages: Belongs to the urocanase family.

230844:Manba
gene id: 230844:Manba
uniprot id: A0A6I9KTD0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycosyl hydrolase 2 family.
messages: Exoglycosidase that cleaves the single beta-linked mannose residue from the non-reducing end of all N-linked glycoprotein oligosaccharides.
messages: Lysosome
messages: Monomer.

230844:Foxo4
gene id: 230844:Foxo4
uniprot id: A0A6I9LLD3
names: Subcellular Location Annotation
messages: Nucleus

230844:Gorab
gene id: 230844:Gorab
uniprot id: A0A6I9L8G0
uniprot id: A0A6J0D6K2
names: Similarity
messages: Belongs to the GORAB family.

230844:Tlx1
gene id: 230844:Tlx1
uniprot id: A0A6I9M0K8
names: Subcellular Location Annotation
messages: Nucleus

230844:LOC102903361
gene id: 230844:LOC102903361
uniprot id: A0A6I9M4M2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase VIIb family.
messages: Membrane
messages: Mitochondrion inner membrane

230844:LOC102918412
gene id: 230844:LOC102918412
uniprot id: A0A6I9M941
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Atp5f1c
gene id: 230844:Atp5f1c
uniprot id: A0A6I9LST4
uniprot id: A0A6I9LY91
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(1) domain and the central stalk which is part of the complex rotary element. The gamma subunit protrudes into the catalytic domain formed of alpha(3)beta(3). Rotation of the central stalk against the surrounding alpha(3)beta(3) subunits leads to hydrolysis of ATP in three separate catalytic sites on the beta subunits.

230844:LOC102921224
gene id: 230844:LOC102921224
uniprot id: A0A6I9MM76
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Slc23a1
gene id: 230844:Slc23a1
uniprot id: A0A6I9M7I0
names: Subcellular Location Annotation
messages: Membrane

230844:LOC102903061
gene id: 230844:LOC102903061
uniprot id: A0A6I9M0A8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Kcnk7
gene id: 230844:Kcnk7
uniprot id: A0A6I9LD41
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
messages: Membrane

230844:Tspyl1
gene id: 230844:Tspyl1
uniprot id: A0A6I9LY47
names: Similarity
messages: Belongs to the nucleosome assembly protein (NAP) family.

230844:Septin6
gene id: 230844:Septin6
uniprot id: A0A6I9M704
uniprot id: A0A6I9MGD4
uniprot id: A0A6J0CH55
uniprot id: A0A6J0CJU5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.
messages: Filament-forming cytoskeletal GTPase.
messages: Septins polymerize into heterooligomeric protein complexes that form filaments.

230844:Yaf2
gene id: 230844:Yaf2
uniprot id: A0A6J0D159
names: Subcellular Location Annotation
messages: Nucleus

230844:LOC102905036
gene id: 230844:LOC102905036
uniprot id: A0A6I9MGT0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:LOC102917748
gene id: 230844:LOC102917748
uniprot id: A0A6I9MNS5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:LOC102912722
gene id: 230844:LOC102912722
uniprot id: A0A6J0CJ49
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

230844:Tmsb4x
gene id: 230844:Tmsb4x
uniprot id: A0A6I9KY83
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thymosin beta family.
messages: Plays an important role in the organization of the cytoskeleton. Binds to and sequesters actin monomers (G actin) and therefore inhibits actin polymerization.
messages: cytoskeleton

230844:Rps6ka6
gene id: 230844:Rps6ka6
uniprot id: A0A6J0CRL6
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily.

230844:Kars1
gene id: 230844:Kars1
uniprot id: A0A6I9L6X2
uniprot id: A0A6I9LAJ8
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.

230844:LOC102913010
gene id: 230844:LOC102913010
uniprot id: A0A6I9M3Y8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Fam193a
gene id: 230844:Fam193a
uniprot id: A0A6I9LKI8
uniprot id: A0A6J0DVH6
names: Similarity
messages: Belongs to the FAM193 family.

230844:Rap2c
gene id: 230844:Rap2c
uniprot id: A0A6I9MHK6
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Ras family.
messages: Endosome membrane
messages: Palmitoylated.
messages: Recycling endosome membrane
messages: Small GTP-binding protein which cycles between a GDP-bound inactive and a GTP-bound active form.

230844:Polrmt
gene id: 230844:Polrmt
uniprot id: A0A6I9LFZ4
uniprot id: A0A6J0DGV7
names: Function
names: Similarity
messages: Belongs to the phage and mitochondrial RNA polymerase family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.

230844:Mrps26
gene id: 230844:Mrps26
uniprot id: A0A6I9LU02
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mS26 family.
messages: Mitochondrion

230844:Pabir1
gene id: 230844:Pabir1
uniprot id: A0A6I9LED9
names: Similarity
messages: Belongs to the FAM122 family.

230844:Rnft1
gene id: 230844:Rnft1
uniprot id: A0A6I9LQG2
names: Subcellular Location Annotation
messages: Membrane

230844:LOC102903154
gene id: 230844:LOC102903154
uniprot id: A0A6I9KVY4
uniprot id: A0A6I9L2I3
uniprot id: A0A6I9L627
uniprot id: A0A6J0ECN5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
messages: Membrane

230844:Trmt11
gene id: 230844:Trmt11
uniprot id: A0A6I9LLK1
names: Function
names: Subunit
messages: Catalytic subunit of an S-adenosyl-L-methionine-dependent tRNA methyltransferase complex that mediates the methylation of the guanosine nucleotide at position 10 (m2G10) in tRNAs.
messages: Interacts with TRMT112.

230844:LOC102907829
gene id: 230844:LOC102907829
uniprot id: A0A6I9LDW9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

230844:LOC102908108
gene id: 230844:LOC102908108
uniprot id: A0A6I9MJP0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the intercrine beta (chemokine CC) family.
messages: Secreted

230844:Slc22a2
gene id: 230844:Slc22a2
uniprot id: A0A6I9L7X1
uniprot id: A0A6J0DAY2
names: Similarity
messages: Belongs to the major facilitator (TC 2.A.1) superfamily. Organic cation transporter (TC 2.A.1.19) family.

230844:Mad1l1
gene id: 230844:Mad1l1
uniprot id: A0A6J0EGQ2
names: Similarity
messages: Belongs to the MAD1 family.

230844:Bud31
gene id: 230844:Bud31
uniprot id: A0A6I9LGZ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BUD31 (G10) family.
messages: Nucleus

230844:Mterf4
gene id: 230844:Mterf4
uniprot id: A0A6I9LSN6
names: Similarity
messages: Belongs to the mTERF family.

230844:Cops8
gene id: 230844:Cops8
uniprot id: A0A6I9LR35
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CSN8 family.
messages: Cytoplasm
messages: Nucleus

230844:Furin
gene id: 230844:Furin
uniprot id: A0A6I9KRV3
names: Similarity
messages: Belongs to the peptidase S8 family.

230844:Xpa
gene id: 230844:Xpa
uniprot id: A0A6I9KYZ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the XPA family.
messages: Nucleus

230844:Clcf1
gene id: 230844:Clcf1
uniprot id: A0A6I9LQ70
uniprot id: A0A6J0DFH8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IL-6 superfamily.
messages: Secreted

230844:Tac4
gene id: 230844:Tac4
uniprot id: A0A6I9KVW8
names: Similarity
messages: Belongs to the tachykinin family.

230844:Sigmar1
gene id: 230844:Sigmar1
uniprot id: A0A6I9LWT7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ERG2 family.
messages: Cell junction
messages: Cytoplasmic vesicle
messages: Endoplasmic reticulum membrane
messages: Functions in lipid transport from the endoplasmic reticulum and is involved in a wide array of cellular functions probably through regulation of the biogenesis of lipid microdomains at the plasma membrane. Regulates calcium efflux at the endoplasmic reticulum.
messages: Homotrimer.
messages: Lipid droplet
messages: Membrane
messages: Nucleus envelope
messages: Nucleus inner membrane
messages: Nucleus outer membrane
messages: Postsynaptic density membrane
messages: The C-terminal helices form a flat, hydrophobic surface that is probably tightly associated with the cytosolic surface of the endoplasmic reticulum membrane.
messages: Vesicle
messages: growth cone

230844:Txlnb
gene id: 230844:Txlnb
uniprot id: A0A6I9LP88
names: Similarity
messages: Belongs to the taxilin family.

230844:Fam47e
gene id: 230844:Fam47e
uniprot id: A0A6I9M480
names: Similarity
messages: Belongs to the FAM47 family.

230844:Eny2
gene id: 230844:Eny2
uniprot id: A0A6I9L943
uniprot id: A0A6J0DCV7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ENY2 family.
messages: Component of the nuclear pore complex (NPC)-associated TREX-2 complex (transcription and export complex 2), composed of at least ENY2, GANP, PCID2, DSS1, and either centrin CETN2 or CETN3. TREX-2 contains 2 ENY2 chains. The TREX-2 complex interacts with the nucleoporin NUP153. Component of some SAGA transcription coactivator-HAT complexes, at least composed of ATXN7, ATXN7L3, ENY2, GCN5L2, SUPT3H, TAF10, TRRAP and USP22. Within the SAGA complex, ENY2, ATXN7, ATXN7L3, and USP22 form an additional subcomplex of SAGA called the DUB module (deubiquitination module). Interacts directly with ATXN7L3, GANP and with the RNA polymerase II. Interacts strongly with ATXN7L3 and ATXN7L3B.
messages: Involved in mRNA export coupled transcription activation by association with both the TREX-2 and the SAGA complexes. The transcription regulatory histone acetylation (HAT) complex SAGA is a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates to a subcomplex that specifically deubiquitinates both histones H2A and H2B. The SAGA complex is recruited to specific gene promoters by activators such as MYC, where it is required for transcription. Required for nuclear receptor-mediated transactivation. The TREX-2 complex functions in docking export-competent ribonucleoprotein particles (mRNPs) to the nuclear entrance of the nuclear pore complex (nuclear basket). TREX-2 participates in mRNA export and accurate chromatin positioning in the nucleus by tethering genes to the nuclear periphery.
messages: nucleoplasm

230844:Gper1
gene id: 230844:Gper1
uniprot id: A0A6I9LVH0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Tradd
gene id: 230844:Tradd
uniprot id: A0A6I9M393
names: Subcellular Location Annotation
messages: Nucleus
messages: cytoskeleton

230844:Gpbp1l1
gene id: 230844:Gpbp1l1
uniprot id: A0A6I9LMG1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vasculin family.
messages: Nucleus

230844:Gch1
gene id: 230844:Gch1
uniprot id: A0A6I9M4U1
names: Similarity
messages: Belongs to the GTP cyclohydrolase I family.

230844:Exosc9
gene id: 230844:Exosc9
uniprot id: A0A6I9M2Q1
names: Subcellular Location Annotation
messages: Cytoplasm

230844:Fam166a
gene id: 230844:Fam166a
uniprot id: A0A6J0DGS1
names: Similarity
messages: Belongs to the CIMIP2 family.

230844:Cmtm2
gene id: 230844:Cmtm2
uniprot id: A0A6J0DAR5
names: Subcellular Location Annotation
messages: Membrane

230844:Ccdc65
gene id: 230844:Ccdc65
uniprot id: A0A6I9L7R3
names: Subcellular Location Annotation
messages: flagellum axoneme

230844:Smad9
gene id: 230844:Smad9
uniprot id: A0A6I9LEI5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dwarfin/SMAD family.
messages: Cytoplasm
messages: Nucleus

230844:Gss
gene id: 230844:Gss
uniprot id: A0A6I9LU78
names: Cofactor
names: Similarity
messages: Belongs to the eukaryotic GSH synthase family.
messages: Binds 1 Mg(2+) ion per subunit.

230844:Sbk1
gene id: 230844:Sbk1
uniprot id: A0A6I9LCG8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
messages: Cytoplasm

230844:Ufd1
gene id: 230844:Ufd1
uniprot id: A0A6I9M1E5
uniprot id: A0A6I9MI24
names: Similarity
messages: Belongs to the UFD1 family.

230844:LOC102903032
gene id: 230844:LOC102903032
uniprot id: A0A6I9M547
names: Similarity
messages: Belongs to the fructosamine kinase family.

230844:LOC102921018
gene id: 230844:LOC102921018
uniprot id: A0A6I9M7Q9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Akr1a1
gene id: 230844:Akr1a1
uniprot id: A0A6I9LMF6
uniprot id: A0A6I9M2U1
names: Similarity
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Belongs to the aldo/keto reductase family.
messages: Cell membrane
messages: Membrane
messages: cytosol

230844:Med14
gene id: 230844:Med14
uniprot id: A0A6I9LCV6
uniprot id: A0A6J0D921
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 14 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex.
messages: Nucleus

230844:Btnl9
gene id: 230844:Btnl9
uniprot id: A0A6I9M3Z9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the immunoglobulin superfamily. BTN/MOG family.
messages: Membrane

230844:Coro2b
gene id: 230844:Coro2b
uniprot id: A0A6I9KV82
names: Similarity
messages: Belongs to the WD repeat coronin family.

230844:Pusl1
gene id: 230844:Pusl1
uniprot id: A0A6I9LXR5
uniprot id: A0A6J0CFZ1
names: Similarity
messages: Belongs to the tRNA pseudouridine synthase TruA family.

230844:LOC102903784
gene id: 230844:LOC102903784
uniprot id: A0A6I9MK82
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Prf1
gene id: 230844:Prf1
uniprot id: A0A6I9L459
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complement C6/C7/C8/C9 family.
messages: Secreted

230844:Agt
gene id: 230844:Agt
uniprot id: A0A6I9LYJ7
uniprot id: A0A6J0CJD6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the serpin family.
messages: Essential component of the renin-angiotensin system (RAS), a potent regulator of blood pressure, body fluid and electrolyte homeostasis.
messages: Secreted
messages: Stimulates aldosterone release.

230844:Ptk6
gene id: 230844:Ptk6
uniprot id: A0A6I9MG17
names: Similarity
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.

230844:Ccr7
gene id: 230844:Ccr7
uniprot id: A0A6I9L5F9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

230844:LOC102908989
gene id: 230844:LOC102908989
uniprot id: A0A6J0DV72
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

230844:Emc6
gene id: 230844:Emc6
uniprot id: A0A6I9MA63
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EMC6 family.
messages: Component of the ER membrane protein complex (EMC).
messages: Endoplasmic reticulum membrane
messages: Membrane

230844:LOC102919618
gene id: 230844:LOC102919618
uniprot id: A0A6J0E709
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CCDC47 family.
messages: Rough endoplasmic reticulum membrane

230844:Cnot8
gene id: 230844:Cnot8
uniprot id: A0A6I9LLP9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CAF1 family.
messages: Nucleus

230844:LOC102921848
gene id: 230844:LOC102921848
uniprot id: A0A6I9M9G6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

230844:LOC102921628
gene id: 230844:LOC102921628
uniprot id: A0A6I9MP33
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:LOC102911659
gene id: 230844:LOC102911659
uniprot id: A0A6J0CNV8
names: Similarity
messages: Belongs to the peptidase M67C family.

230844:Ffar2
gene id: 230844:Ffar2
uniprot id: A0A6I9LFV3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:LOC102904090
gene id: 230844:LOC102904090
uniprot id: A0A6I9M2E4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Chmp3
gene id: 230844:Chmp3
uniprot id: A0A6I9MBI7
names: Similarity
messages: Belongs to the SNF7 family.

230844:Abcc1
gene id: 230844:Abcc1
uniprot id: A0A6I9LHK0
uniprot id: A0A6I9LXC2
uniprot id: A0A6J0DY74
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCC family. Conjugate transporter (TC 3.A.1.208) subfamily.
messages: Cell membrane
messages: Membrane

230844:Fam110c
gene id: 230844:Fam110c
uniprot id: A0A6I9MA53
names: Similarity
messages: Belongs to the FAM110 family.

230844:Kremen2
gene id: 230844:Kremen2
uniprot id: A0A6I9M580
uniprot id: A0A6I9MLP0
names: Caution
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Receptor for Dickkopf proteins. Cooperates with DKK1/2 to inhibit Wnt/beta-catenin signaling by promoting the endocytosis of Wnt receptors LRP5 and LRP6.

230844:LOC102927946
gene id: 230844:LOC102927946
uniprot id: A0A6I9LU35
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Slc6a5
gene id: 230844:Slc6a5
uniprot id: A0A6I9M5T0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

230844:LOC102904643
gene id: 230844:LOC102904643
uniprot id: A0A6I9M7V6
names: Similarity
messages: Belongs to the PRAME family.

230844:LOC102905218
gene id: 230844:LOC102905218
uniprot id: A0A6J0CEW8
names: Similarity
messages: Belongs to the sorting nexin family.

230844:Top2b
gene id: 230844:Top2b
uniprot id: A0A6J0D1X6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type II topoisomerase family.
messages: Homodimer.
messages: Key decatenating enzyme that alters DNA topology by binding to two double-stranded DNA molecules, generating a double-stranded break in one of the strands, passing the intact strand through the broken strand, and religating the broken strand.
messages: nucleolus
messages: nucleoplasm

230844:Dact2
gene id: 230844:Dact2
uniprot id: A0A6J0D6H9
names: Similarity
messages: Belongs to the dapper family.

230844:Ptdss1
gene id: 230844:Ptdss1
uniprot id: A0A6I9LEC7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phosphatidyl serine synthase family.
messages: Catalyzes a base-exchange reaction in which the polar head group of phosphatidylethanolamine (PE) is replaced by L-serine.
messages: Endoplasmic reticulum membrane
messages: Membrane

230844:LOC102925016
gene id: 230844:LOC102925016
uniprot id: A0A6J0CGB7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:LOC102908783
gene id: 230844:LOC102908783
uniprot id: A0A6I9LLY0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AB hydrolase superfamily. LDAH family.
messages: Lipid droplet

230844:Otop1
gene id: 230844:Otop1
uniprot id: A0A6I9LW07
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the otopetrin family.
messages: Cell membrane
messages: Membrane

230844:Rev1
gene id: 230844:Rev1
uniprot id: A0A6I9LAX0
uniprot id: A0A6I9LKV2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-Y family.
messages: Deoxycytidyl transferase involved in DNA repair. Transfers a dCMP residue from dCTP to the 3'-end of a DNA primer in a template-dependent reaction. May assist in the first step in the bypass of abasic lesions by the insertion of a nucleotide opposite the lesion. Required for normal induction of mutations by physical and chemical agents.
messages: Nucleus

230844:Fam102b
gene id: 230844:Fam102b
uniprot id: A0A6I9LHV9
names: Similarity
messages: Belongs to the EEIG family.

230844:Lpar3
gene id: 230844:Lpar3
uniprot id: A0A6J0DVV6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Appl2
gene id: 230844:Appl2
uniprot id: A0A6J0CHS3
uniprot id: A0A6J0CJW3
names: Subcellular Location Annotation
messages: Early endosome membrane
messages: Endosome membrane
messages: Membrane
messages: Nucleus
messages: phagosome
messages: ruffle

230844:LOC102904129
gene id: 230844:LOC102904129
uniprot id: A0A6I9MKK9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Casp2
gene id: 230844:Casp2
uniprot id: A0A6I9MI02
names: Similarity
messages: Belongs to the peptidase C14A family.

230844:Scamp1
gene id: 230844:Scamp1
uniprot id: A0A6I9LDK3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SCAMP family.
messages: Membrane

230844:Npepl1
gene id: 230844:Npepl1
uniprot id: A0A6J0D684
names: Similarity
messages: Belongs to the peptidase M17 family.

230844:Mfap2
gene id: 230844:Mfap2
uniprot id: A0A6I9L1Z6
uniprot id: A0A6I9LDL5
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MFAP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

230844:LOC102922083
gene id: 230844:LOC102922083
uniprot id: A0A6I9LKQ4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Tim17/Tim22/Tim23 family.
messages: Component of the TIM23 complex at least composed of TIMM23, TIMM17 (TIMM17A or TIMM17B) and TIMM50.
messages: Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Mitochondrion inner membrane

230844:B4galt6
gene id: 230844:B4galt6
uniprot id: A0A6I9KYV8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 7 family.
messages: Golgi apparatus membrane
messages: Membrane
messages: Responsible for the synthesis of complex-type N-linked oligosaccharides in many glycoproteins as well as the carbohydrate moieties of glycolipids.

230844:Hdac5
gene id: 230844:Hdac5
uniprot id: A0A6I9KT43
uniprot id: A0A6I9KTS9
uniprot id: A0A6I9KZQ7
uniprot id: A0A6I9L2L8
uniprot id: A0A6J0D7J0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone deacetylase family. HD type 2 subfamily.
messages: Nucleus
messages: Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.

230844:Psmd4
gene id: 230844:Psmd4
uniprot id: A0A6I9M1Y5
uniprot id: A0A6I9MIP6
names: Similarity
messages: Belongs to the proteasome subunit S5A family.

230844:Nat10
gene id: 230844:Nat10
uniprot id: A0A6I9L2Q1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA cytidine acetyltransferase family. NAT10 subfamily.
messages: Interacts with THUMPD1.
messages: RNA cytidine acetyltransferase with specificity toward both 18S rRNA and tRNAs. Catalyzes the formation of N(4)-acetylcytidine (ac4C) in 18S rRNA. Required for early nucleolar cleavages of precursor rRNA at sites A0, A1 and A2 during 18S rRNA synthesis. Catalyzes the formation of ac4C in serine and leucine tRNAs. Requires the tRNA-binding adapter protein THUMPD1 for full tRNA acetyltransferase activity but not for 18S rRNA acetylation.
messages: nucleolus

230844:Rimbp2
gene id: 230844:Rimbp2
uniprot id: A0A6I9L150
uniprot id: A0A6J0DQW7
uniprot id: A0A6J0DSH6
uniprot id: A0A6J0DU46
uniprot id: A0A6J0DU50
uniprot id: A0A6J0DU75
names: Similarity
messages: Belongs to the RIMBP family.

230844:Azin2
gene id: 230844:Azin2
uniprot id: A0A6J0CND0
uniprot id: A0A6J0CQN8
uniprot id: A0A6J0CSN7
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family.

230844:Adk
gene id: 230844:Adk
uniprot id: A0A6I9LJ18
uniprot id: A0A6I9LYV5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP dependent phosphorylation of adenosine and other related nucleoside analogs to monophosphate derivatives.
messages: Belongs to the carbohydrate kinase PfkB family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Monomer.
messages: Nucleus

230844:Hs6st1
gene id: 230844:Hs6st1
uniprot id: A0A6I9M4A5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 6-O-sulfation enzyme which catalyzes the transfer of sulfate from 3'-phosphoadenosine 5'-phosphosulfate (PAPS) to position 6 of the N-sulfoglucosamine residue (GlcNS) of heparan sulfate.
messages: Belongs to the sulfotransferase 6 family.
messages: Membrane

230844:Lmod1
gene id: 230844:Lmod1
uniprot id: A0A6I9LQ30
names: Subcellular Location Annotation
messages: cytoskeleton
messages: sarcomere

230844:Utp14a
gene id: 230844:Utp14a
uniprot id: A0A6I9M9T9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UTP14 family.
messages: nucleolus

230844:LOC102923418
gene id: 230844:LOC102923418
uniprot id: A0A6I9M1P3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Adcy4
gene id: 230844:Adcy4
uniprot id: A0A6I9M365
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
messages: Binds 2 magnesium ions per subunit. Is also active with manganese (in vitro).
messages: Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.
messages: Membrane

230844:LOC102902992
gene id: 230844:LOC102902992
uniprot id: A0A6I9MES9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Psmd12
gene id: 230844:Psmd12
uniprot id: A0A6I9KTJ0
names: Similarity
messages: Belongs to the proteasome subunit p55 family.

230844:Lad1
gene id: 230844:Lad1
uniprot id: A0A6I9LGI3
names: Function
names: Subcellular Location Annotation
messages: Anchoring filament protein which is a component of the basement membrane zone.
messages: basement membrane

230844:Fundc2
gene id: 230844:Fundc2
uniprot id: A0A6I9M802
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FUN14 family.
messages: Mitochondrion outer membrane

230844:Cep70
gene id: 230844:Cep70
uniprot id: A0A6I9LCZ3
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Directly interacts with tubulin-gamma; this interaction determines centrosomal localization.
messages: Plays a role in the organization of both preexisting and nascent microtubules in interphase cells. During mitosis, required for the organization and orientation of the mitotic spindle.
messages: centrosome

230844:Cryba4
gene id: 230844:Cryba4
uniprot id: A0A6I9LJX5
names: Similarity
messages: Belongs to the beta/gamma-crystallin family.

230844:Uba7
gene id: 230844:Uba7
uniprot id: A0A6I9LJY6
names: Similarity
messages: Belongs to the ubiquitin-activating E1 family.

230844:Kiaa1191
gene id: 230844:Kiaa1191
uniprot id: A0A6I9L4C7
uniprot id: A0A6I9L5C9
uniprot id: A0A6I9LGN4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the P33MONOX family.
messages: Cytoplasm
messages: Interacts with NELFB, NOL12 and PRNP.
messages: Potential NADPH-dependent oxidoreductase. May be involved in the regulation of neuronal survival, differentiation and axonal outgrowth.

230844:Eif3m
gene id: 230844:Eif3m
uniprot id: A0A6I9LEH8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CSN7/EIF3M family. CSN7 subfamily.
messages: Belongs to the eIF-3 subunit M family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is composed of 13 subunits: EIF3A, EIF3B, EIF3C, EIF3D, EIF3E, EIF3F, EIF3G, EIF3H, EIF3I, EIF3J, EIF3K, EIF3L and EIF3M. The eIF-3 complex appears to include 3 stable modules: module A is composed of EIF3A, EIF3B, EIF3G and EIF3I; module B is composed of EIF3F, EIF3H, and EIF3M; and module C is composed of EIF3C, EIF3D, EIF3E, EIF3K and EIF3L. EIF3C of module C binds EIF3B of module A and EIF3H of module B, thereby linking the three modules. EIF3J is a labile subunit that binds to the eIF-3 complex via EIF3B. The eIF-3 complex interacts with RPS6KB1 under conditions of nutrient depletion. Mitogenic stimulation leads to binding and activation of a complex composed of MTOR and RPTOR, leading to phosphorylation and release of RPS6KB1 and binding of EIF4B to eIF-3.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation, including cell cycling, differentiation and apoptosis, and uses different modes of RNA stem-loop binding to exert either translational activation or repression.
messages: Cytoplasm

230844:Mmp16
gene id: 230844:Mmp16
uniprot id: A0A6I9LRN9
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M10A family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Can bind about 5 Ca(2+) ions per subunit.

230844:Anxa3
gene id: 230844:Anxa3
uniprot id: A0A6I9LDD2
names: Domain
names: Similarity
messages: A pair of annexin repeats may form one binding site for calcium and phospholipid.
messages: Belongs to the annexin family.

230844:Sirt3
gene id: 230844:Sirt3
uniprot id: A0A6I9L4X4
uniprot id: A0A6J0DDY2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the sirtuin family. Class I subfamily.
messages: Binds 1 zinc ion per subunit.
messages: NAD-dependent protein deacetylase.

230844:Hoxc13
gene id: 230844:Hoxc13
uniprot id: A0A6I9LMN0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Abd-B homeobox family.
messages: Nucleus

230844:Trpm3
gene id: 230844:Trpm3
uniprot id: A0A6I9LK59
uniprot id: A0A6I9LK67
uniprot id: A0A6I9LK73
uniprot id: A0A6I9LMP2
uniprot id: A0A6I9LMP9
uniprot id: A0A6I9LMQ7
uniprot id: A0A6I9LMR2
uniprot id: A0A6I9LV15
uniprot id: A0A6I9LV22
uniprot id: A0A6I9LV28
uniprot id: A0A6I9LVK0
uniprot id: A0A6I9LVK2
uniprot id: A0A6I9LVK7
uniprot id: A0A6I9M0I0
uniprot id: A0A6I9M0J0
uniprot id: A0A6I9M0K3
uniprot id: A0A6J0DTU7
uniprot id: A0A6J0E216
names: Subcellular Location Annotation
messages: Membrane

230844:Ppdpf
gene id: 230844:Ppdpf
uniprot id: A0A6J0CL63
names: Similarity
messages: Belongs to the PPDPF family.

230844:Cdca7l
gene id: 230844:Cdca7l
uniprot id: A0A6I9LUB7
uniprot id: A0A6I9M2N7
uniprot id: A0A6J0E557
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

230844:St6galnac4
gene id: 230844:St6galnac4
uniprot id: A0A6J0DRR4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

230844:LOC102928728
gene id: 230844:LOC102928728
uniprot id: A0A6I9M045
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL39 family.

230844:LOC102913247
gene id: 230844:LOC102913247
uniprot id: A0A6I9LY46
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Arid1b
gene id: 230844:Arid1b
uniprot id: A0A6J0DBR3
names: Subcellular Location Annotation
messages: Nucleus

230844:Fmnl1
gene id: 230844:Fmnl1
uniprot id: A0A6I9KT09
uniprot id: A0A6I9KZL4
uniprot id: A0A6J0D4W7
uniprot id: A0A6J0DB15
names: Similarity
messages: Belongs to the formin homology family.

230844:Mab21l1
gene id: 230844:Mab21l1
uniprot id: A0A6I9LE83
names: Similarity
messages: Belongs to the mab-21 family.

230844:Mea1
gene id: 230844:Mea1
uniprot id: A0A6I9MB64
uniprot id: A0A6J0EA11
names: Function
messages: May play an important role in spermatogenesis and/or testis development.

230844:Pbrm1
gene id: 230844:Pbrm1
uniprot id: A0A6I9LD13
uniprot id: A0A6I9LET4
uniprot id: A0A6I9LNA1
uniprot id: A0A6I9LSI4
uniprot id: A0A6J0DKU2
uniprot id: A0A6J0DL54
uniprot id: A0A6J0DRW8
names: Subcellular Location Annotation
messages: Nucleus

230844:Arhgdia
gene id: 230844:Arhgdia
uniprot id: A0A6J0E546
names: Similarity
messages: Belongs to the Rho GDI family.

230844:Golga4
gene id: 230844:Golga4
uniprot id: A0A6I9LMQ8
uniprot id: A0A6J0DXP5
uniprot id: A0A6J0DZD4
names: Subcellular Location Annotation
messages: Membrane

230844:Il6r
gene id: 230844:Il6r
uniprot id: A0A6I9L3F5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type I cytokine receptor family. Type 3 subfamily.
messages: Membrane

230844:Pla2g5
gene id: 230844:Pla2g5
uniprot id: A0A6J0DGA6
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phospholipase A2 family.
messages: Binds 1 Ca(2+) ion per subunit.
messages: Secreted

230844:Bdkrb2
gene id: 230844:Bdkrb2
uniprot id: A0A6I9L1S4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Forms a complex with PECAM1 and GNAQ. Interacts with PECAM1.
messages: Membrane
messages: Receptor for bradykinin. It is associated with G proteins that activate a phosphatidylinositol-calcium second messenger system.

230844:LOC107399532
gene id: 230844:LOC107399532
uniprot id: A0A6J0CJ57
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

230844:LOC102926200
gene id: 230844:LOC102926200
uniprot id: A0A6J0CVQ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Dclre1a
gene id: 230844:Dclre1a
uniprot id: A0A6I9L792
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA repair metallo-beta-lactamase (DRMBL) family.
messages: Nucleus

230844:Kif26b
gene id: 230844:Kif26b
uniprot id: A0A6I9L7D7
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

230844:Usp3
gene id: 230844:Usp3
uniprot id: A0A6I9LHL6
names: Function
names: Similarity
messages: Belongs to the peptidase C19 family.
messages: Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes.

230844:LOC102927071
gene id: 230844:LOC102927071
uniprot id: A0A6I9MCU9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2B family.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

230844:Acsl5
gene id: 230844:Acsl5
uniprot id: A0A6I9L779
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP-dependent AMP-binding enzyme family.
messages: Catalyzes the conversion of long-chain fatty acids to their active form acyl-CoAs for both synthesis of cellular lipids, and degradation via beta-oxidation.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Mitochondrion outer membrane

230844:Uckl1
gene id: 230844:Uckl1
uniprot id: A0A6I9MFZ5
uniprot id: A0A6I9MID0
uniprot id: A0A6J0CL41
uniprot id: A0A6J0CPN0
names: Similarity
messages: Belongs to the uridine kinase family.

230844:Gmppb
gene id: 230844:Gmppb
uniprot id: A0A6I9LFP5
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

230844:Leprotl1
gene id: 230844:Leprotl1
uniprot id: A0A6J0D0W4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OB-RGRP/VPS55 family.
messages: Membrane

230844:Lcn10
gene id: 230844:Lcn10
uniprot id: A0A6I9LR92
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calycin superfamily. Lipocalin family.
messages: Secreted

230844:Med12
gene id: 230844:Med12
uniprot id: A0A6I9LMF5
uniprot id: A0A6J0DH36
uniprot id: A0A6J0DH41
uniprot id: A0A6J0DJH6
uniprot id: A0A6J0DQG1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Mediator complex subunit 12 family.
messages: Nucleus

230844:Ccni
gene id: 230844:Ccni
uniprot id: A0A6J0E3L4
names: Similarity
messages: Belongs to the cyclin family.

230844:LOC102902936
gene id: 230844:LOC102902936
uniprot id: A0A6I9LSW1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:LOC102928219
gene id: 230844:LOC102928219
uniprot id: A0A6I9L9W3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GST superfamily. Theta family.
messages: Cytoplasm
messages: Homodimer.

230844:Engase
gene id: 230844:Engase
uniprot id: A0A6I9LTV7
uniprot id: A0A6J0E8L4
uniprot id: A0A6J0EAH4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 85 family.
messages: cytosol

230844:LOC102909240
gene id: 230844:LOC102909240
uniprot id: A0A6J0CXJ1
names: Function
names: Similarity
messages: Belongs to the peptidase C19 family.
messages: Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes.

230844:Rdh14
gene id: 230844:Rdh14
uniprot id: A0A6I9LCX6
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

230844:LOC102902788
gene id: 230844:LOC102902788
uniprot id: A0A6J0DDY8
names: Similarity
messages: Belongs to the CD225/Dispanin family.

230844:Rpl8
gene id: 230844:Rpl8
uniprot id: A0A6I9M6Y7
names: Similarity
messages: Belongs to the universal ribosomal protein uL2 family.

230844:Il10
gene id: 230844:Il10
uniprot id: A0A6I9MHJ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IL-10 family.
messages: Immune regulatory cytokine.
messages: Secreted

230844:Esyt1
gene id: 230844:Esyt1
uniprot id: A0A6I9M075
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the extended synaptotagmin family.
messages: Cell membrane
messages: Endoplasmic reticulum membrane
messages: Membrane

230844:Hps3
gene id: 230844:Hps3
uniprot id: A0A6I9MBL5
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Component of the biogenesis of lysosome-related organelles complex-2 (or BLOC2) composed of HPS3, HPS5 and HPS6.
messages: Cytoplasm
messages: Involved in early stages of melanosome biogenesis and maturation.

230844:Mnd1
gene id: 230844:Mnd1
uniprot id: A0A6J0DUZ4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MND1 family.
messages: Nucleus
messages: Required for proper homologous chromosome pairing and efficient cross-over and intragenic recombination during meiosis.

230844:LOC102906939
gene id: 230844:LOC102906939
uniprot id: A0A6I9M0E6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. Aurora subfamily.
messages: centrosome

230844:Ecel1
gene id: 230844:Ecel1
uniprot id: A0A6I9LK52
names: Subcellular Location Annotation
messages: Membrane

230844:Nrxn2
gene id: 230844:Nrxn2
uniprot id: A0A6J0DI13
uniprot id: A0A6J0DI40
uniprot id: A0A6J0DNS9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

230844:Wnt11
gene id: 230844:Wnt11
uniprot id: A0A6J0DN18
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

230844:Slco4a1
gene id: 230844:Slco4a1
uniprot id: A0A6I9LEV4
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the organo anion transporter (TC 2.A.60) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

230844:Mrps11
gene id: 230844:Mrps11
uniprot id: A0A6I9L164
names: Similarity
messages: Belongs to the universal ribosomal protein uS11 family.

230844:Stk40
gene id: 230844:Stk40
uniprot id: A0A6I9LK62
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: May be a negative regulator of NF-kappa-B and p53-mediated gene transcription.
messages: Nucleus

230844:Luc7l
gene id: 230844:Luc7l
uniprot id: A0A6I9L9D2
uniprot id: A0A6I9LGM7
names: Similarity
messages: Belongs to the Luc7 family.

230844:Ltbr
gene id: 230844:Ltbr
uniprot id: A0A6I9M396
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

230844:Vma21
gene id: 230844:Vma21
uniprot id: A0A6I9LWS2
uniprot id: A0A6J0EGV9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associates with the V0 complex of the vacuolar ATPase (V-ATPase).
messages: Belongs to the VMA21 family.
messages: COPII-coated vesicle membrane
messages: Endoplasmic reticulum membrane
messages: Endoplasmic reticulum-Golgi intermediate compartment membrane
messages: Required for the assembly of the V0 complex of the vacuolar ATPase (V-ATPase) in the endoplasmic reticulum.

230844:Izumo1r
gene id: 230844:Izumo1r
uniprot id: A0A6I9M5A3
names: Similarity
messages: Belongs to the folate receptor family.

230844:Sulf1
gene id: 230844:Sulf1
uniprot id: A0A6I9L8C6
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfatase family.
messages: Binds 1 Ca(2+) ion per subunit.
messages: Cell surface
messages: Endoplasmic reticulum
messages: Exhibits arylsulfatase activity and highly specific endoglucosamine-6-sulfatase activity. It can remove sulfate from the C-6 position of glucosamine within specific subregions of intact heparin.
messages: Golgi stack
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

230844:Psapl1
gene id: 230844:Psapl1
uniprot id: A0A6I9LVZ2
names: Function
names: Subcellular Location Annotation
messages: May activate the lysosomal degradation of sphingolipids.
messages: Secreted

230844:Rrn3
gene id: 230844:Rrn3
uniprot id: A0A6I9LXD1
names: Similarity
messages: Belongs to the RRN3 family.

230844:Plxna1
gene id: 230844:Plxna1
uniprot id: A0A6I9M9G7
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the plexin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

230844:Nr6a1
gene id: 230844:Nr6a1
uniprot id: A0A6I9M4E2
uniprot id: A0A6I9M936
uniprot id: A0A6J0CH82
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

230844:Elf2
gene id: 230844:Elf2
uniprot id: A0A6I9LEA9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

230844:Slc7a8
gene id: 230844:Slc7a8
uniprot id: A0A6I9LUS3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. L-type amino acid transporter (LAT) (TC 2.A.3.8) family.
messages: Cell membrane
messages: Membrane

230844:Gcat
gene id: 230844:Gcat
uniprot id: A0A6I9LH89
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.

230844:Tg
gene id: 230844:Tg
uniprot id: A0A6I9LJN1
names: Caution
names: Similarity
messages: Belongs to the type-B carboxylesterase/lipase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

230844:Tmem18
gene id: 230844:Tmem18
uniprot id: A0A6I9LT28
uniprot id: A0A6I9M3T7
uniprot id: A0A6J0ECV4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM18 family.
messages: Membrane
messages: Nucleus membrane

230844:Pfdn5
gene id: 230844:Pfdn5
uniprot id: A0A6I9LFF0
names: Similarity
messages: Belongs to the prefoldin subunit alpha family.

230844:LOC102910884
gene id: 230844:LOC102910884
uniprot id: A0A6I9LJ41
uniprot id: A0A6J0DR55
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Interacts with UHRF2/NIRF.
messages: May be involved in cell cycle regulation.
messages: Nucleus

230844:Ddx1
gene id: 230844:Ddx1
uniprot id: A0A6I9L4V3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DEAD box helicase family. DDX1 subfamily.
messages: Cytoplasmic granule
messages: RNA helicase.
messages: The helicase domain is involved in the stimulation of RELA transcriptional activity.

230844:Dmap1
gene id: 230844:Dmap1
uniprot id: A0A6J0CU89
names: Subcellular Location Annotation
messages: Nucleus

230844:Atp1b2
gene id: 230844:Atp1b2
uniprot id: A0A6I9L5J7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the X(+)/potassium ATPases subunit beta family.
messages: Membrane
messages: This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane.

230844:Amfr
gene id: 230844:Amfr
uniprot id: A0A6J0DX57
names: Subcellular Location Annotation
messages: Membrane

230844:LOC102928084
gene id: 230844:LOC102928084
uniprot id: A0A6J0CZM7
names: Similarity
messages: Belongs to the TIP41 family.

230844:Inhba
gene id: 230844:Inhba
uniprot id: A0A6J0DMG3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TGF-beta family.
messages: Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition. Inhibins appear to oppose the functions of activins.
messages: Secreted

230844:Acp5
gene id: 230844:Acp5
uniprot id: A0A6I9LEP9
names: Cofactor
messages: Binds 2 iron ions per subunit.

230844:Eif2d
gene id: 230844:Eif2d
uniprot id: A0A6I9M307
uniprot id: A0A6I9MEK4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eIF2D family.
messages: Cytoplasm
messages: Translation initiation factor that is able to deliver tRNA to the P-site of the eukaryotic ribosome in a GTP-independent manner. The binding of Met-tRNA(I) occurs after the AUG codon finds its position in the P-site of 40S ribosomes, the situation that takes place during initiation complex formation on some specific RNAs. Its activity in tRNA binding with 40S subunits does not require the presence of the aminoacyl moiety. Possesses the unique ability to deliver non-Met (elongator) tRNAs into the P-site of the 40S subunit. In addition to its role in initiation, can promote release of deacylated tRNA and mRNA from recycled 40S subunits following ABCE1-mediated dissociation of post-termination ribosomal complexes into subunits.

230844:Atp11c
gene id: 230844:Atp11c
uniprot id: A0A6J0CHZ3
uniprot id: A0A6J0CKJ1
uniprot id: A0A6J0CMJ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.
messages: Membrane

230844:Unc50
gene id: 230844:Unc50
uniprot id: A0A6J0DHI4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the unc-50 family.
messages: Membrane
messages: Nucleus inner membrane

230844:LOC102925551
gene id: 230844:LOC102925551
uniprot id: A0A6I9MFD7
names: Similarity
messages: Belongs to the CDC50/LEM3 family.

230844:Apoa1
gene id: 230844:Apoa1
uniprot id: A0A6I9M630
names: Similarity
messages: Belongs to the apolipoprotein A1/A4/E family.

230844:Adamts6
gene id: 230844:Adamts6
uniprot id: A0A6J0DNQ2
names: Caution
names: Cofactor
names: Subcellular Location Annotation
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

230844:Dgkk
gene id: 230844:Dgkk
uniprot id: A0A6I9MAM5
names: Similarity
messages: Belongs to the eukaryotic diacylglycerol kinase family.

230844:Scrn3
gene id: 230844:Scrn3
uniprot id: A0A6J0CPK9
names: Similarity
messages: Belongs to the peptidase C69 family. Secernin subfamily.

230844:Cpeb4
gene id: 230844:Cpeb4
uniprot id: A0A6I9L9E6
uniprot id: A0A6I9LHE6
uniprot id: A0A6J0DDF8
uniprot id: A0A6J0DE55
names: Similarity
messages: Belongs to the RRM CPEB family.

230844:Csrnp3
gene id: 230844:Csrnp3
uniprot id: A0A6I9L611
uniprot id: A0A6J0D7E0
uniprot id: A0A6J0D9M6
uniprot id: A0A6J0DDW6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AXUD1 family.
messages: Nucleus

230844:Cep57
gene id: 230844:Cep57
uniprot id: A0A6I9MBY9
names: Similarity
messages: Belongs to the translokin family.

230844:Mxra8
gene id: 230844:Mxra8
uniprot id: A0A6I9M402
uniprot id: A0A6J0CG77
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

230844:Hmmr
gene id: 230844:Hmmr
uniprot id: A0A6I9KVI2
names: Subcellular Location Annotation
messages: spindle

230844:Pola1
gene id: 230844:Pola1
uniprot id: A0A6I9M4E0
names: Similarity
messages: Belongs to the DNA polymerase type-B family.

230844:Tmem43
gene id: 230844:Tmem43
uniprot id: A0A6I9KX01
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM43 family.
messages: Membrane

230844:Syne3
gene id: 230844:Syne3
uniprot id: A0A6I9ML91
uniprot id: A0A6J0CTP6
names: Similarity
messages: Belongs to the nesprin family.

230844:Oc90
gene id: 230844:Oc90
uniprot id: A0A6I9LKL7
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phospholipase A2 family.
messages: Binds 1 Ca(2+) ion per subunit.
messages: Secreted

230844:LOC102924471
gene id: 230844:LOC102924471
uniprot id: A0A6I9M4J0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the p22phox family.
messages: Cell membrane
messages: Composed of a heavy chain (beta) and a light chain (alpha). Component of an NADPH oxidase complex composed of a heterodimer formed by the membrane proteins CYBA and CYBB and the cytosolic subunits NCF1, NCF2 and NCF4. Interacts with NCF1 (via SH3 domain).
messages: Critical component of the membrane-bound oxidase of phagocytes that generates superoxide. Associates with NOX3 to form a functional NADPH oxidase constitutively generating superoxide.
messages: Membrane

230844:LOC102928819
gene id: 230844:LOC102928819
uniprot id: A0A6I9LI02
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Dhfr
gene id: 230844:Dhfr
uniprot id: A0A6I9LQ06
names: Similarity
messages: Belongs to the dihydrofolate reductase family.

230844:Mcoln2
gene id: 230844:Mcoln2
uniprot id: A0A6I9LUD1
names: Subcellular Location Annotation
messages: Endosome membrane
messages: Membrane

230844:Cps1
gene id: 230844:Cps1
uniprot id: A0A6I9L146
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

230844:Cog6
gene id: 230844:Cog6
uniprot id: A0A6I9LEK2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the COG6 family.
messages: Component of the conserved oligomeric Golgi complex which is composed of eight different subunits and is required for normal Golgi morphology and localization.
messages: Golgi apparatus membrane
messages: Membrane
messages: Required for normal Golgi function.

230844:LOC102911423
gene id: 230844:LOC102911423
uniprot id: A0A6I9M3Y5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Cfap299
gene id: 230844:Cfap299
uniprot id: A0A6I9L9Q8
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: May be involved in spermatogenesis.
messages: Nucleus

230844:Gpr137b
gene id: 230844:Gpr137b
uniprot id: A0A6I9LC06
names: Subcellular Location Annotation
messages: Lysosome membrane
messages: Membrane

230844:LOC102919030
gene id: 230844:LOC102919030
uniprot id: A0A6J0E734
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

230844:Tmem214
gene id: 230844:Tmem214
uniprot id: A0A6I9MHZ7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TMEM214 family.
messages: Constitutively interacts with CASP4; required for the localization of procaspase 4 to the ER.
messages: Critical mediator, in cooperation with CASP4, of endoplasmic reticulum-stress induced apoptosis. Required or the activation of CASP4 following endoplasmic reticulum stress.
messages: Endoplasmic reticulum membrane
messages: Membrane

230844:Krt15
gene id: 230844:Krt15
uniprot id: A0A6I9LYN9
names: Similarity
messages: Belongs to the intermediate filament family.

230844:Vps26b
gene id: 230844:Vps26b
uniprot id: A0A6I9L4U2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VPS26 family.
messages: Endosome

230844:Unc5a
gene id: 230844:Unc5a
uniprot id: A0A6I9L4B7
uniprot id: A0A6I9LGM3
uniprot id: A0A6J0D8D1
uniprot id: A0A6J0DD20
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the unc-5 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for netrin required for axon guidance. Mediates axon repulsion of neuronal growth cones in the developing nervous system upon ligand binding.

230844:Id1
gene id: 230844:Id1
uniprot id: A0A6I9LKE0
names: Subcellular Location Annotation
messages: Nucleus

230844:Pus10
gene id: 230844:Pus10
uniprot id: A0A6I9L8I5
names: Similarity
messages: Belongs to the pseudouridine synthase Pus10 family.

230844:LOC102911730
gene id: 230844:LOC102911730
uniprot id: A0A6I9LZL7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:LOC102921248
gene id: 230844:LOC102921248
uniprot id: A0A6I9LIW9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Fam166c
gene id: 230844:Fam166c
uniprot id: A0A6I9MHM7
names: Similarity
messages: Belongs to the CIMIP2 family.

230844:Ripor1
gene id: 230844:Ripor1
uniprot id: A0A6J0DXV5
uniprot id: A0A6J0DZL0
uniprot id: A0A6J0E0X3
names: Similarity
messages: Belongs to the RIPOR family.

230844:LOC102906468
gene id: 230844:LOC102906468
uniprot id: A0A6I9MGK8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Gpc2
gene id: 230844:Gpc2
uniprot id: A0A6J0DVF3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glypican family.
messages: Cell membrane
messages: Cell surface proteoglycan.

230844:Brms1l
gene id: 230844:Brms1l
uniprot id: A0A6I9LJX2
names: Subcellular Location Annotation
messages: Nucleus

230844:Tbx20
gene id: 230844:Tbx20
uniprot id: A0A6I9LWE0
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

230844:Ston2
gene id: 230844:Ston2
uniprot id: A0A6I9M4A0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Adapter protein involved in endocytic machinery. Involved in the synaptic vesicle recycling. May facilitate clathrin-coated vesicle uncoating.
messages: Belongs to the Stoned B family.
messages: Cytoplasm
messages: synaptosome

230844:Ebag9
gene id: 230844:Ebag9
uniprot id: A0A6I9LH27
names: Function
names: Subcellular Location Annotation
messages: Golgi apparatus membrane
messages: May participate in suppression of cell proliferation and induces apoptotic cell death through activation of interleukin-1-beta converting enzyme (ICE)-like proteases.

230844:LOC102905367
gene id: 230844:LOC102905367
uniprot id: A0A6I9MP13
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Tgfbr2
gene id: 230844:Tgfbr2
uniprot id: A0A6I9KSE3
uniprot id: A0A6J0CRM8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
messages: Cell membrane
messages: Membrane
messages: Membrane raft
messages: Transmembrane serine/threonine kinase forming with the TGF-beta type I serine/threonine kinase receptor, TGFBR1, the non-promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinogenesis. The formation of the receptor complex composed of 2 TGFBR1 and 2 TGFBR2 molecules symmetrically bound to the cytokine dimer results in the phosphorylation and the activation of TGFRB1 by the constitutively active TGFBR2. Activated TGFBR1 phosphorylates SMAD2 which dissociates from the receptor and interacts with SMAD4. The SMAD2-SMAD4 complex is subsequently translocated to the nucleus where it modulates the transcription of the TGF-beta-regulated genes. This constitutes the canonical SMAD-dependent TGF-beta signaling cascade. Also involved in non-canonical, SMAD-independent TGF-beta signaling pathways.

230844:Ca5a
gene id: 230844:Ca5a
uniprot id: A0A6I9M5V1
names: Function
names: Similarity
messages: Belongs to the alpha-carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

230844:Tmem9b
gene id: 230844:Tmem9b
uniprot id: A0A6I9L8V6
uniprot id: A0A6I9LG59
names: Similarity
messages: Belongs to the TMEM9 family.

230844:LOC102913291
gene id: 230844:LOC102913291
uniprot id: A0A6I9LLI6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Zdhhc7
gene id: 230844:Zdhhc7
uniprot id: A0A6I9LYS4
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

230844:Impdh2
gene id: 230844:Impdh2
uniprot id: A0A6I9L6Z8
uniprot id: A0A6I9LG62
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Could also have a single-stranded nucleic acid-binding activity and could play a role in RNA and/or DNA metabolism. It may also have a role in the development of malignancy and the growth progression of some tumors.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.
messages: Nucleus

230844:Twf1
gene id: 230844:Twf1
uniprot id: A0A6I9L060
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the actin-binding proteins ADF family. Twinfilin subfamily.
messages: cytoskeleton

230844:Apcs
gene id: 230844:Apcs
uniprot id: A0A6I9LUG9
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pentraxin family.
messages: Binds 2 calcium ions per subunit.
messages: Homopentamer. Pentaxin (or pentraxin) have a discoid arrangement of 5 non-covalently bound subunits.
messages: Secreted

230844:Opa3
gene id: 230844:Opa3
uniprot id: A0A6I9M7C3
uniprot id: A0A6J0CK92
names: Function
names: Similarity
messages: Belongs to the OPA3 family.
messages: May play some role in mitochondrial processes.

230844:Trim56
gene id: 230844:Trim56
uniprot id: A0A6J0DMJ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRIM/RBCC family.
messages: Cytoplasm

230844:Ror1
gene id: 230844:Ror1
uniprot id: A0A6I9KZR2
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. ROR subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

230844:Art5
gene id: 230844:Art5
uniprot id: A0A6J0CHX6
uniprot id: A0A6J0CKU7
names: Similarity
messages: Belongs to the Arg-specific ADP-ribosyltransferase family.

230844:LOC102904307
gene id: 230844:LOC102904307
uniprot id: A0A6I9M124
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

230844:LOC102926885
gene id: 230844:LOC102926885
uniprot id: A0A6I9M162
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c-type heme lyase family.
messages: Lyase that catalyzes the covalent linking of the heme group to the cytochrome C apoprotein to produce the mature functional cytochrome.
messages: Membrane
messages: Mitochondrion inner membrane

230844:LOC102905349
gene id: 230844:LOC102905349
uniprot id: A0A6J0CQK9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Dtx4
gene id: 230844:Dtx4
uniprot id: A0A6I9M662
uniprot id: A0A6I9MH81
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Deltex family.
messages: Cytoplasm

230844:Fgf14
gene id: 230844:Fgf14
uniprot id: A0A6I9LGJ0
uniprot id: A0A6I9LKV8
uniprot id: A0A6J0DIL1
names: Similarity
messages: Belongs to the heparin-binding growth factors family.

230844:Map2k3
gene id: 230844:Map2k3
uniprot id: A0A6I9KYR4
names: Similarity
messages: Belongs to the protein kinase superfamily.

230844:Lta4h
gene id: 230844:Lta4h
uniprot id: A0A6I9LUQ2
uniprot id: A0A6I9M199
uniprot id: A0A6I9M309
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M1 family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm

230844:LOC102927819
gene id: 230844:LOC102927819
uniprot id: A0A6I9MNT5
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

230844:Kansl2
gene id: 230844:Kansl2
uniprot id: A0A6I9LB90
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: As part of the NSL complex it is involved in acetylation of nucleosomal histone H4 on several lysine residues and therefore may be involved in the regulation of transcription.
messages: Component of the NSL complex at least composed of MOF/KAT8, KANSL1, KANSL2, KANSL3, MCRS1, PHF20, OGT1/OGT, WDR5 and HCFC1.
messages: Nucleus

230844:Il7r
gene id: 230844:Il7r
uniprot id: A0A6I9M6U7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type I cytokine receptor family. Type 4 subfamily.
messages: Membrane

230844:Map3k10
gene id: 230844:Map3k10
uniprot id: A0A6I9M459
names: Activity Regulation
names: Similarity
names: Subunit
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.
messages: Homodimer.
messages: Homodimerization via the leucine zipper domains is required for autophosphorylation.

230844:Ypel1
gene id: 230844:Ypel1
uniprot id: A0A6I9MCL3
names: Similarity
messages: Belongs to the yippee family.

230844:Ppp1r11
gene id: 230844:Ppp1r11
uniprot id: A0A6I9MJ67
names: Subunit
messages: Interacts with TLR2 and UBE2D2.

230844:Zfhx4
gene id: 230844:Zfhx4
uniprot id: A0A6I9L7J9
uniprot id: A0A6I9LEX9
names: Subcellular Location Annotation
messages: Nucleus

230844:Gpc4
gene id: 230844:Gpc4
uniprot id: A0A6I9MH19
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glypican family.
messages: Cell membrane
messages: Cell surface proteoglycan.

230844:Abcc12
gene id: 230844:Abcc12
uniprot id: A0A6I9KVC3
names: Subcellular Location Annotation
messages: Membrane

230844:Gpr68
gene id: 230844:Gpr68
uniprot id: A0A6I9M2M7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

230844:Rpl11
gene id: 230844:Rpl11
uniprot id: A0A6I9LDG1
names: Similarity
messages: Belongs to the universal ribosomal protein uL5 family.

230844:Ldhd
gene id: 230844:Ldhd
uniprot id: A0A6I9KZS9
names: Similarity
messages: Belongs to the FAD-binding oxidoreductase/transferase type 4 family.

230844:LOC102906526
gene id: 230844:LOC102906526
uniprot id: A0A6J0DUX1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2B family.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

230844:Rce1
gene id: 230844:Rce1
uniprot id: A0A6I9LB74
uniprot id: A0A6I9LQ84
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase U48 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

230844:LOC102922354
gene id: 230844:LOC102922354
uniprot id: A0A6I9M752
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:LOC102903894
gene id: 230844:LOC102903894
uniprot id: A0A6I9LBS9
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the osteocalcin/matrix Gla protein family.
messages: Binds strongly to apatite and calcium.
messages: Gamma-carboxyglutamate residues are formed by vitamin K dependent carboxylation. These residues are essential for the binding of calcium.
messages: Secreted

230844:LOC102909439
gene id: 230844:LOC102909439
uniprot id: A0A6I9MDV6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM182 family.
messages: Cell membrane
messages: Membrane

230844:Ripor2
gene id: 230844:Ripor2
uniprot id: A0A6I9LDB8
names: Similarity
messages: Belongs to the RIPOR family.

230844:Ints12
gene id: 230844:Ints12
uniprot id: A0A6J0CYI8
names: Similarity
names: Subunit
messages: Belongs to the Integrator subunit 12 family.
messages: Belongs to the multiprotein complex Integrator, at least composed of INTS1, INTS2, INTS3, INTS4, INTS5, INTS6, INTS7, INTS8, INTS9/RC74, INTS10, INTS11/CPSF3L and INTS12.

230844:LOC102918762
gene id: 230844:LOC102918762
uniprot id: A0A6I9M5V4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Frem2
gene id: 230844:Frem2
uniprot id: A0A6I9LEJ6
names: Similarity
messages: Belongs to the FRAS1 family.

230844:LOC102927525
gene id: 230844:LOC102927525
uniprot id: A0A6I9LA73
names: Similarity
messages: Belongs to the cytochrome c oxidase VIIa family.

230844:Mettl14
gene id: 230844:Mettl14
uniprot id: A0A6I9M9D0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MT-A70-like family.
messages: Heterodimer; heterodimerizes with METTL3 to form an antiparallel heterodimer that constitutes an active methyltransferase.
messages: Nucleus
messages: The METTL3-METTL14 heterodimer forms a N6-methyltransferase complex that methylates adenosine residues at the N(6) position of some mRNAs and regulates the circadian clock, differentiation of embryonic stem cells and cortical neurogenesis. In the heterodimer formed with METTL3, METTL14 constitutes the RNA-binding scaffold that recognizes the substrate rather than the catalytic core. N6-methyladenosine (m6A), which takes place at the 5'-[AG]GAC-3' consensus sites of some mRNAs, plays a role in mRNA stability and processing. M6A acts as a key regulator of mRNA stability by promoting mRNA destabilization and degradation. In embryonic stem cells (ESCs), m6A methylation of mRNAs encoding key naive pluripotency-promoting transcripts results in transcript destabilization. M6A regulates spermatogonial differentiation and meiosis and is essential for male fertility and spermatogenesis. M6A also regulates cortical neurogenesis: m6A methylation of transcripts related to transcription factors, neural stem cells, the cell cycle and neuronal differentiation during brain development promotes their destabilization and decay, promoting differentiation of radial glial cells.

230844:Tmem86a
gene id: 230844:Tmem86a
uniprot id: A0A6I9M6L8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM86 family.
messages: Membrane

230844:Dgat2l6
gene id: 230844:Dgat2l6
uniprot id: A0A6I9LMG8
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the diacylglycerol acyltransferase family.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

230844:LOC102927036
gene id: 230844:LOC102927036
uniprot id: A0A6I9LXN7
names: Similarity
messages: Belongs to the type-B carboxylesterase/lipase family.

230844:Il13ra2
gene id: 230844:Il13ra2
uniprot id: A0A6J0E9K9
uniprot id: A0A6J0EBU3
uniprot id: A0A6J0EDB1
names: Subcellular Location Annotation
messages: Membrane

230844:Erlec1
gene id: 230844:Erlec1
uniprot id: A0A6I9MC38
uniprot id: A0A6I9MG52
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OS-9 family.
messages: Endoplasmic reticulum lumen
messages: Lectin involved in the quality control of the secretory pathway. As a member of the endoplasmic reticulum-associated degradation lumenal (ERAD-L) surveillance system, targets misfolded endoplasmic reticulum lumenal glycoproteins for degradation.

230844:Llgl2
gene id: 230844:Llgl2
uniprot id: A0A6I9M069
uniprot id: A0A6J0CK32
uniprot id: A0A6J0CLZ3
names: Similarity
messages: Belongs to the WD repeat L(2)GL family.

230844:Rpl10l
gene id: 230844:Rpl10l
uniprot id: A0A6I9M3J4
names: Similarity
messages: Belongs to the universal ribosomal protein uL16 family.

230844:Fam118b
gene id: 230844:Fam118b
uniprot id: A0A6I9LBB3
uniprot id: A0A6I9LJM8
uniprot id: A0A6J0DFU7
uniprot id: A0A6J0DGF4
names: Similarity
messages: Belongs to the FAM118 family.

230844:LOC102905723
gene id: 230844:LOC102905723
uniprot id: A0A6J0E7X9
names: Similarity
messages: Belongs to the TPPP family.

230844:Rpl7a
gene id: 230844:Rpl7a
uniprot id: A0A6I9M5V0
names: Function
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL8 family.
messages: Component of the ribosome.

230844:Pcid2
gene id: 230844:Pcid2
uniprot id: A0A6I9LCN4
names: Similarity
messages: Belongs to the CSN12 family.

230844:LOC102921608
gene id: 230844:LOC102921608
uniprot id: A0A6I9M3U0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor T2R family.
messages: Membrane

230844:Sez6l
gene id: 230844:Sez6l
uniprot id: A0A6I9LHZ9
uniprot id: A0A6I9LT83
uniprot id: A0A6J0DT66
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

230844:Ext1
gene id: 230844:Ext1
uniprot id: A0A6J0DN39
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 47 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

230844:Spcs3
gene id: 230844:Spcs3
uniprot id: A0A6I9L399
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPCS3 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

230844:Cyld
gene id: 230844:Cyld
uniprot id: A0A6J0E3L8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: centrosome
messages: cilium basal body
messages: perinuclear region
messages: spindle

230844:Parvg
gene id: 230844:Parvg
uniprot id: A0A6I9LPF5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the parvin family.
messages: Cell membrane
messages: Membrane

230844:LOC102918295
gene id: 230844:LOC102918295
uniprot id: A0A6I9LZ64
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Apoe
gene id: 230844:Apoe
uniprot id: A0A6I9M236
names: Similarity
messages: Belongs to the apolipoprotein A1/A4/E family.

230844:Srprb
gene id: 230844:Srprb
uniprot id: A0A6I9L917
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SRP receptor beta subunit family.
messages: Endoplasmic reticulum membrane
messages: Membrane

230844:Uchl1
gene id: 230844:Uchl1
uniprot id: A0A6I9L0L7
names: Similarity
messages: Belongs to the peptidase C12 family.

230844:Myadm
gene id: 230844:Myadm
uniprot id: A0A6I9M2S2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MAL family.
messages: Membrane

230844:Polr2e
gene id: 230844:Polr2e
uniprot id: A0A6I9LFI3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the archaeal Rpo5/eukaryotic RPB5 RNA polymerase subunit family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non-coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively. Pol II is the central component of the basal RNA polymerase II transcription machinery. Pols are composed of mobile elements that move relative to each other. In Pol II, POLR2E/RPB5 is part of the lower jaw surrounding the central large cleft and thought to grab the incoming DNA template. Seems to be the major component in this process.
messages: Nucleus

230844:Esr2
gene id: 230844:Esr2
uniprot id: A0A6I9KXX2
uniprot id: A0A6J0CWE2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR3 subfamily.
messages: Nucleus

230844:Mccc2
gene id: 230844:Mccc2
uniprot id: A0A6I9MCT4
names: Similarity
messages: Belongs to the AccD/PCCB family.

230844:LOC102907393
gene id: 230844:LOC102907393
uniprot id: A0A6I9LZV1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

230844:Rbm48
gene id: 230844:Rbm48
uniprot id: A0A6I9M6K7
names: Function
names: Similarity
names: Subunit
messages: As a component of the minor spliceosome, involved in the splicing of U12-type introns in pre-mRNAs.
messages: Belongs to the RBM48 family.
messages: Component of the minor spliceosome. Within this complex, interacts with ARMC7 and PRPF8/PRP8.

230844:LOC102905224
gene id: 230844:LOC102905224
uniprot id: A0A6I9ME51
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:LOC102923901
gene id: 230844:LOC102923901
uniprot id: A0A6J0CMH8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vasculin family.
messages: Nucleus

230844:LOC102906025
gene id: 230844:LOC102906025
uniprot id: A0A6I9LMM3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

230844:Ces4a
gene id: 230844:Ces4a
uniprot id: A0A6I9LMX5
uniprot id: A0A6J0E644
names: Similarity
messages: Belongs to the type-B carboxylesterase/lipase family.

230844:Grhl2
gene id: 230844:Grhl2
uniprot id: A0A6I9LQR1
names: Subcellular Location Annotation
messages: Nucleus

230844:Cops7a
gene id: 230844:Cops7a
uniprot id: A0A6I9M374
uniprot id: A0A6I9MDD8
uniprot id: A0A6J0CD78
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CSN7/EIF3M family. CSN7 subfamily.
messages: Component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF-type complexes such as SCF, CSA or DDB2. The complex is also involved in phosphorylation of p53/TP53, JUN, I-kappa-B-alpha/NFKBIA, ITPK1 and IRF8/ICSBP, possibly via its association with CK2 and PKD kinases. CSN-dependent phosphorylation of TP53 and JUN promotes and protects degradation by the Ubl system, respectively.
messages: Cytoplasm
messages: Nucleus

230844:Intu
gene id: 230844:Intu
uniprot id: A0A6I9M0K6
uniprot id: A0A6J0E7M7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inturned family.
messages: Cell surface
messages: cilium basal body

230844:Cct2
gene id: 230844:Cct2
uniprot id: A0A6I9LRQ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TCP-1 chaperonin family.
messages: Cytoplasm

230844:Prl
gene id: 230844:Prl
uniprot id: A0A6I9MJY2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the somatotropin/prolactin family.
messages: Secreted

230844:LOC102914354
gene id: 230844:LOC102914354
uniprot id: A0A6I9LX69
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic/archaeal RNase P protein component 1 family.
messages: Component of nuclear RNase P and RNase MRP.
messages: Component of ribonuclease P, a ribonucleoprotein complex that generates mature tRNA molecules by cleaving their 5'-ends.
messages: nucleolus

230844:Tfcp2
gene id: 230844:Tfcp2
uniprot id: A0A6I9LMV3
uniprot id: A0A6J0DT12
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the grh/CP2 family. CP2 subfamily.
messages: Nucleus

230844:Cxcl9
gene id: 230844:Cxcl9
uniprot id: A0A6I9LZV5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the intercrine alpha (chemokine CxC) family.
messages: Secreted

230844:Galnt6
gene id: 230844:Galnt6
uniprot id: A0A6I9LMV1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
messages: Golgi apparatus membrane
messages: Membrane

230844:Lonp1
gene id: 230844:Lonp1
uniprot id: A0A6I9LNI1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of misfolded, unassembled or oxidatively damaged polypeptides as well as certain short-lived regulatory proteins in the mitochondrial matrix. May also have a chaperone function in the assembly of inner membrane protein complexes. Participates in the regulation of mitochondrial gene expression and in the maintenance of the integrity of the mitochondrial genome. Binds to mitochondrial promoters and RNA in a single-stranded, site-specific, and strand-specific manner. May regulate mitochondrial DNA replication and/or gene expression using site-specific, single-stranded DNA binding to target the degradation of regulatory proteins binding to adjacent sites in mitochondrial promoters.
messages: Belongs to the peptidase S16 family.
messages: Homohexamer. Organized in a ring with a central cavity. The ATP-binding and proteolytic domains (AP-domain) form a hexameric chamber, while the N-terminal domain is arranged as a trimer of dimers. DNA and RNA binding is stimulated by substrate and inhibited by ATP binding. Interacts with TWNK and mitochondrial DNA polymerase subunit POLG.
messages: Mitochondrion matrix

230844:Il12b
gene id: 230844:Il12b
uniprot id: A0A6I9L1J9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associates with IL23A to form the IL-23 interleukin, a heterodimeric cytokine which functions in innate and adaptive immunity. IL-23 may constitute with IL-17 an acute response to infection in peripheral tissues. IL-23 binds to a heterodimeric receptor complex composed of IL12RB1 and IL23R, activates the Jak-Stat signaling cascade, stimulates memory rather than naive T-cells and promotes production of pro-inflammatory cytokines. IL-23 induces autoimmune inflammation and thus may be responsible for autoimmune inflammatory diseases and may be important for tumorigenesis.
messages: Belongs to the IL-12B family.
messages: Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated killer cells, and stimulate the production of IFN-gamma by resting PBMC.
messages: Heterodimer with IL12A; disulfide-linked. The heterodimer is known as interleukin IL-12.
messages: Secreted

230844:Plcb1
gene id: 230844:Plcb1
uniprot id: A0A6I9LHQ8
uniprot id: A0A6I9LXI1
names: Cofactor
names: Function
messages: Binds 1 Ca(2+) ion per subunit.
messages: The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes.

230844:LOC102913236
gene id: 230844:LOC102913236
uniprot id: A0A6I9M0E0
names: Similarity
messages: Belongs to the serpin family.

230844:Atp6v1c2
gene id: 230844:Atp6v1c2
uniprot id: A0A6J0D643
uniprot id: A0A6J0D7A6
uniprot id: A0A6J0D7T9
uniprot id: A0A6J0D8A2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the V-ATPase C subunit family.
messages: Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment. Subunit C is necessary for the assembly of the catalytic sector of the enzyme and is likely to have a specific function in its catalytic activity.
messages: V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex. The V1 complex consists of three catalytic AB heterodimers that form a heterohexamer, three peripheral stalks each consisting of EG heterodimers, one central rotor including subunits D and F, and the regulatory subunits C and H. The proton translocation complex V0 consists of the proton transport subunit a, a ring of proteolipid subunits c9c'', rotary subunit d, subunits e and f, and two accessory subunits.

230844:Fam174a
gene id: 230844:Fam174a
uniprot id: A0A6I9M8W5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAM174 family.
messages: Membrane

230844:Arrb2
gene id: 230844:Arrb2
uniprot id: A0A6I9M0W1
names: Similarity
messages: Belongs to the arrestin family.

230844:Zc3h12d
gene id: 230844:Zc3h12d
uniprot id: A0A6I9LKK3
names: Similarity
messages: Belongs to the ZC3H12 family.

230844:Plin4
gene id: 230844:Plin4
uniprot id: A0A6I9LNG0
names: Similarity
messages: Belongs to the perilipin family.

230844:LOC102904534
gene id: 230844:LOC102904534
uniprot id: A0A6I9MLC2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Mrpl1
gene id: 230844:Mrpl1
uniprot id: A0A6I9MMR0
uniprot id: A0A6J0CVQ7
names: Subcellular Location Annotation
messages: Mitochondrion

230844:LOC102913665
gene id: 230844:LOC102913665
uniprot id: A0A6I9MB73
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the galanin family.
messages: Hypothalamic neuropeptide which binds to the G-protein-coupled galanin receptors (GALR1, GALR2 and GALR3). Involved in a large number of putative physiological functions in CNS homeostatic processes, including the regulation of gonadotropin-releasing hormone secretion.
messages: Secreted

230844:Stx1b
gene id: 230844:Stx1b
uniprot id: A0A6I9L5S3
names: Similarity
messages: Belongs to the syntaxin family.

230844:Kcne1
gene id: 230844:Kcne1
uniprot id: A0A6J0DNY8
names: Similarity
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Belongs to the potassium channel KCNE family.
messages: Cell membrane
messages: Membrane

230844:LOC102916241
gene id: 230844:LOC102916241
uniprot id: A0A6I9LSS9
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

230844:Ppp1cc
gene id: 230844:Ppp1cc
uniprot id: A0A6J0DGD5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PPP phosphatase family. PP-1 subfamily.
messages: nucleolus
messages: nucleoplasm

230844:Glis2
gene id: 230844:Glis2
uniprot id: A0A6I9LUA2
uniprot id: A0A6J0DVL5
names: Similarity
messages: Belongs to the GLI C2H2-type zinc-finger protein family.

230844:Nr4a3
gene id: 230844:Nr4a3
uniprot id: A0A6J0CZF8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR4 subfamily.
messages: Nucleus

230844:Ntng2
gene id: 230844:Ntng2
uniprot id: A0A6J0DQY9
uniprot id: A0A6J0DRE8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

230844:Anapc10
gene id: 230844:Anapc10
uniprot id: A0A6J0E2B6
names: Function
names: Similarity
messages: Belongs to the APC10 family.
messages: Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin-protein ligase complex that controls progression through mitosis and the G1 phase of the cell cycle.

230844:Ctnnd1
gene id: 230844:Ctnnd1
uniprot id: A0A6I9LSQ6
uniprot id: A0A6I9M900
names: Similarity
messages: Belongs to the beta-catenin family.

230844:Pnn
gene id: 230844:Pnn
uniprot id: A0A6I9M3T1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pinin family.
messages: Found in a mRNA splicing-dependent exon junction complex (EJC). Found in a complex with SR proteins. Found in a mRNP complex with RNPS1. Component of the PSAP complex consisting of RNPS1, SAP18 and PNN. Interacts with PNISR, CTBP1, CTBP2, KRT8, KRT18, KRT19, PS1D/PNO40, PPIG, RNPS1, SFRS4 and SRRM2. Identified in the spliceosome C complex.
messages: Nucleus speckle
messages: desmosome

230844:Pacs1
gene id: 230844:Pacs1
uniprot id: A0A6I9LKB8
names: Similarity
messages: Belongs to the PACS family.

230844:Igfbp5
gene id: 230844:Igfbp5
uniprot id: A0A6I9KW74
names: Caution
names: Function
names: Subcellular Location Annotation
messages: IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

230844:LOC102922900
gene id: 230844:LOC102922900
uniprot id: A0A6J0DTF4
names: Subcellular Location Annotation
messages: mitochondrion nucleoid

230844:Tgfb1
gene id: 230844:Tgfb1
uniprot id: A0A6I9M230
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TGF-beta family.
messages: Homodimer; disulfide-linked.
messages: Transforming growth factor beta-1 proprotein: Precursor of the Latency-associated peptide (LAP) and Transforming growth factor beta-1 (TGF-beta-1) chains, which constitute the regulatory and active subunit of TGF-beta-1, respectively.
messages: extracellular matrix

230844:LOC102909501
gene id: 230844:LOC102909501
uniprot id: A0A6I9LDV9
names: Similarity
messages: Belongs to the intermediate filament family.

230844:Hus1
gene id: 230844:Hus1
uniprot id: A0A6I9KXY7
uniprot id: A0A6I9L861
uniprot id: A0A6J0CXK3
names: Similarity
messages: Belongs to the HUS1 family.

230844:LOC102913418
gene id: 230844:LOC102913418
uniprot id: A0A6I9LU18
names: Similarity
messages: Belongs to the histone H3 family.

230844:Klhl3
gene id: 230844:Klhl3
uniprot id: A0A6I9L472
uniprot id: A0A6J0D6H6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KLHL3 family.
messages: cytoskeleton
messages: cytosol

230844:Sbk2
gene id: 230844:Sbk2
uniprot id: A0A6J0CFL9
names: Similarity
messages: Belongs to the protein kinase superfamily.

230844:Rab39b
gene id: 230844:Rab39b
uniprot id: A0A6I9MIK3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Cell membrane
messages: Membrane

230844:St8sia3
gene id: 230844:St8sia3
uniprot id: A0A6I9LZT4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

230844:Dynll1
gene id: 230844:Dynll1
uniprot id: A0A6I9MFF7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in changing or maintaining the spatial distribution of cytoskeletal structures.
messages: Belongs to the dynein light chain family.
messages: cytoskeleton

230844:Ifngr1
gene id: 230844:Ifngr1
uniprot id: A0A6I9M1V4
names: Similarity
messages: Belongs to the type II cytokine receptor family.

230844:Psen2
gene id: 230844:Psen2
uniprot id: A0A6I9L766
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase A22A family.
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Homodimer.
messages: Membrane
messages: Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors.
messages: The PAL motif is required for normal active site conformation.

230844:Plin1
gene id: 230844:Plin1
uniprot id: A0A6I9KYJ6
names: Similarity
messages: Belongs to the perilipin family.

230844:LOC102910403
gene id: 230844:LOC102910403
uniprot id: A0A6I9KZK4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Arf family.
messages: GTP-binding protein involved in protein trafficking; modulates vesicle budding and uncoating within the Golgi apparatus.
messages: Golgi apparatus

230844:LOC102904825
gene id: 230844:LOC102904825
uniprot id: A0A6J0D204
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat fritz family.
messages: Cell membrane
messages: Membrane
messages: cilium axoneme

230844:Nmi
gene id: 230844:Nmi
uniprot id: A0A6I9LB19
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NMI family.
messages: Cytoplasm
messages: Nucleus
messages: Secreted

230844:Fshr
gene id: 230844:Fshr
uniprot id: A0A6I9LWA3
uniprot id: A0A6J0DWE3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily.
messages: Cell membrane
messages: G protein-coupled receptor for follitropin, the follicle-stimulating hormone. Through cAMP production activates the downstream PI3K-AKT and ERK1/ERK2 signaling pathways.
messages: Membrane

230844:Tmprss6
gene id: 230844:Tmprss6
uniprot id: A0A6J0DCC2
uniprot id: A0A6J0DEN5
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

230844:LOC102927784
gene id: 230844:LOC102927784
uniprot id: A0A6J0CK63
names: Similarity
messages: Belongs to the AB hydrolase superfamily. AB hydrolase 2 family.

230844:Prpf3
gene id: 230844:Prpf3
uniprot id: A0A6I9LUY0
names: Function
names: Subcellular Location Annotation
messages: Nucleus
messages: Plays a role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex).

230844:LOC102914062
gene id: 230844:LOC102914062
uniprot id: A0A6I9LT49
uniprot id: A0A6I9M1B0
uniprot id: A0A6J0E3R7
names: Subcellular Location Annotation
messages: Membrane

230844:Pdia3
gene id: 230844:Pdia3
uniprot id: A0A6I9MET6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein disulfide isomerase family.
messages: Endoplasmic reticulum lumen

230844:LOC102913002
gene id: 230844:LOC102913002
uniprot id: A0A6I9LTZ8
names: Similarity
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. IRG family.

230844:Tmem200b
gene id: 230844:Tmem200b
uniprot id: A0A6I9LDT8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM200 family.
messages: Membrane

230844:Arg1
gene id: 230844:Arg1
uniprot id: A0A6I9LYG0
names: Cofactor
names: Similarity
messages: Belongs to the arginase family.
messages: Binds 2 manganese ions per subunit.

230844:Masp2
gene id: 230844:Masp2
uniprot id: A0A6I9L257
uniprot id: A0A6I9L9G6
uniprot id: A0A6J0D394
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

230844:Xpot
gene id: 230844:Xpot
uniprot id: A0A6I9L5B1
uniprot id: A0A6J0D296
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exportin family.
messages: Cytoplasm
messages: Nucleus
messages: tRNA nucleus export receptor which facilitates tRNA translocation across the nuclear pore complex.

230844:Nek6
gene id: 230844:Nek6
uniprot id: A0A6J0CG75
names: Similarity
messages: Belongs to the protein kinase superfamily.

230844:Nfxl1
gene id: 230844:Nfxl1
uniprot id: A0A6I9LB39
names: Similarity
messages: Belongs to the NFX1 family.

230844:LOC102923613
gene id: 230844:LOC102923613
uniprot id: A0A6I9MNT7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Pde3a
gene id: 230844:Pde3a
uniprot id: A0A6I9L3Q6
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

230844:Dedd
gene id: 230844:Dedd
uniprot id: A0A6I9LUK9
names: Subcellular Location Annotation
messages: nucleolus

230844:Kcnk10
gene id: 230844:Kcnk10
uniprot id: A0A6I9M5E6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
messages: Membrane

230844:Babam2
gene id: 230844:Babam2
uniprot id: A0A6J0E0V1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BABAM2 family.
messages: Component of the ARISC complex. Component of the BRCA1-A complex. Component of the BRISC complex. Binds polyubiquitin.
messages: Contains 2 ubiquitin-conjugating enzyme family-like (UEV-like) regions. These regions lack the critical Cys residues required for ubiquitination but retain the ability to bind ubiquitin.
messages: Cytoplasm
messages: May play a role in homeostasis or cellular differentiation in cells of neural, epithelial and germline origins. May also act as a death receptor-associated anti-apoptotic protein, which inhibits the mitochondrial apoptotic pathway.
messages: Nucleus

230844:Kiss1r
gene id: 230844:Kiss1r
uniprot id: A0A6I9LFI6
names: Subcellular Location Annotation
messages: Membrane

230844:Pcyt2
gene id: 230844:Pcyt2
uniprot id: A0A6I9LSZ2
uniprot id: A0A6I9M151
uniprot id: A0A6J0E230
names: Similarity
messages: Belongs to the cytidylyltransferase family.

230844:Myo10
gene id: 230844:Myo10
uniprot id: A0A6I9LDJ0
uniprot id: A0A6I9LT66
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
messages: cytoskeleton

230844:Rpl34
gene id: 230844:Rpl34
uniprot id: A0A6I9KYZ9
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL34 family.

230844:Vegfb
gene id: 230844:Vegfb
uniprot id: A0A6I9LDA8
uniprot id: A0A6I9LQM0
names: Similarity
messages: Belongs to the PDGF/VEGF growth factor family.

230844:Fibin
gene id: 230844:Fibin
uniprot id: A0A6I9LLM9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FIBIN family.
messages: Endoplasmic reticulum
messages: Golgi apparatus
messages: Homodimer; disulfide-linked. Seems to also exist as monomers.
messages: Secreted

230844:Psmf1
gene id: 230844:Psmf1
uniprot id: A0A6I9LN14
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the proteasome inhibitor PI31 family.
messages: Cytoplasm
messages: Endoplasmic reticulum
messages: Plays an important role in control of proteasome function. Inhibits the hydrolysis of protein and peptide substrates by the 20S proteasome. Also inhibits the activation of the proteasome by the proteasome regulatory proteins PA700 and PA28.

230844:Mdm4
gene id: 230844:Mdm4
uniprot id: A0A6I9LZI7
uniprot id: A0A6I9MAI7
uniprot id: A0A6J0CG15
uniprot id: A0A6J0CIS6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MDM2/MDM4 family.
messages: Inhibits p53- and p73-mediated cell cycle arrest and apoptosis by binding its transcriptional activation domain.
messages: Nucleus

230844:Rab3gap1
gene id: 230844:Rab3gap1
uniprot id: A0A6I9MA39
uniprot id: A0A6J0CJN5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Rab3-GAP catalytic subunit family.
messages: Cytoplasm
messages: Endoplasmic reticulum

230844:Mb
gene id: 230844:Mb
uniprot id: A0A6I9M3P7
names: Function
names: Similarity
messages: Belongs to the globin family.
messages: Serves as a reserve supply of oxygen and facilitates the movement of oxygen within muscles.

230844:Sin3a
gene id: 230844:Sin3a
uniprot id: A0A6I9KVD5
names: Subcellular Location Annotation
messages: Nucleus

230844:LOC102908404
gene id: 230844:LOC102908404
uniprot id: A0A6I9L5U6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family.
messages: Membrane

230844:LOC102909371
gene id: 230844:LOC102909371
uniprot id: A0A6I9MKG8
names: Similarity
messages: Belongs to the WD repeat EBI family.

230844:Pax9
gene id: 230844:Pax9
uniprot id: A0A6I9M3S3
names: Subcellular Location Annotation
messages: Nucleus

230844:Stk35
gene id: 230844:Stk35
uniprot id: A0A6J0DU62
names: Similarity
messages: Belongs to the protein kinase superfamily.

230844:Defb123
gene id: 230844:Defb123
uniprot id: A0A6I9LKE5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the beta-defensin family.
messages: Has antibacterial activity.
messages: Secreted

230844:B3gat3
gene id: 230844:B3gat3
uniprot id: A0A6I9MEB9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 43 family.
messages: Golgi apparatus membrane
messages: Membrane

230844:Calhm5
gene id: 230844:Calhm5
uniprot id: A0A6I9LTM1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CALHM family.
messages: Membrane

230844:LOC102906692
gene id: 230844:LOC102906692
uniprot id: A0A6I9MC00
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Capn12
gene id: 230844:Capn12
uniprot id: A0A6I9LP78
names: Similarity
messages: Belongs to the peptidase C2 family.

230844:Alad
gene id: 230844:Alad
uniprot id: A0A6I9LAU4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Catalyzes an early step in the biosynthesis of tetrapyrroles. Binds two molecules of 5-aminolevulinate per subunit, each at a distinct site, and catalyzes their condensation to form porphobilinogen.
messages: Homooctamer; active form. Homohexamer; low activity form.

230844:Il5
gene id: 230844:Il5
uniprot id: A0A6I9MKV1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IL-5 family.
messages: Homodimer; disulfide-linked.
messages: Homodimeric cytokine expressed predominantly by T-lymphocytes and NK cells that plays an important role in the survival, differentiation, and chemotaxis of eosinophils. Acts also on activated and resting B-cells to induce immunoglobulin production, growth, and differentiation. Mechanistically, exerts its biological effects through a receptor composed of IL5RA subunit and the cytokine receptor common subunit beta/CSF2RB. Binding to the receptor leads to activation of various kinases including LYN, SYK and JAK2 and thereby propagates signals through the RAS-MAPK and JAK-STAT5 pathways respectively.
messages: Secreted

230844:Znf174
gene id: 230844:Znf174
uniprot id: A0A6I9LUB6
names: Subcellular Location Annotation
messages: Nucleus

230844:Golga1
gene id: 230844:Golga1
uniprot id: A0A6I9M4D5
names: Subcellular Location Annotation
messages: Membrane

230844:Men1
gene id: 230844:Men1
uniprot id: A0A6I9LD80
uniprot id: A0A6I9LLE6
names: Subcellular Location Annotation
messages: Nucleus

230844:Sh2b2
gene id: 230844:Sh2b2
uniprot id: A0A6I9L0V1
names: Similarity
messages: Belongs to the SH2B adapter family.

230844:Mrgprf
gene id: 230844:Mrgprf
uniprot id: A0A6I9LCQ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

230844:Itgb7
gene id: 230844:Itgb7
uniprot id: A0A6I9LMQ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin beta chain family.
messages: Cell membrane
messages: Membrane

230844:Chmp6
gene id: 230844:Chmp6
uniprot id: A0A6I9LT16
uniprot id: A0A6I9M183
names: Similarity
messages: Belongs to the SNF7 family.

230844:Greb1
gene id: 230844:Greb1
uniprot id: A0A6J0DCC3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GREB1 family.
messages: Membrane

230844:Pipox
gene id: 230844:Pipox
uniprot id: A0A6I9LE04
names: Similarity
messages: Belongs to the MSOX/MTOX family.

230844:LOC102920706
gene id: 230844:LOC102920706
uniprot id: A0A6I9MIC3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:LOC102914639
gene id: 230844:LOC102914639
uniprot id: A0A6I9LI88
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase VIIb family.
messages: Membrane
messages: Mitochondrion inner membrane

230844:Gpm6b
gene id: 230844:Gpm6b
uniprot id: A0A6I9KXZ5
uniprot id: A0A6I9KY87
uniprot id: A0A6I9L4Y4
uniprot id: A0A6I9L8I7
uniprot id: A0A6J0CWG7
uniprot id: A0A6J0D1N1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the myelin proteolipid protein family.
messages: Membrane

230844:Pyy
gene id: 230844:Pyy
uniprot id: A0A6J0D8K2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NPY family.
messages: Secreted

230844:Fam20c
gene id: 230844:Fam20c
uniprot id: A0A6I9MFX3
names: Similarity
messages: Belongs to the FAM20 family.

230844:Eef2k
gene id: 230844:Eef2k
uniprot id: A0A6I9LPL8
names: Activity Regulation
names: Similarity
names: Subunit
messages: Belongs to the protein kinase superfamily. Alpha-type protein kinase family.
messages: Monomer or homodimer.
messages: Undergoes calcium/calmodulin-dependent intramolecular autophosphorylation, and this results in it becoming partially calcium/calmodulin-independent.

230844:Lce5a
gene id: 230844:Lce5a
uniprot id: A0A6I9L397
names: Similarity
messages: Belongs to the LCE family.

230844:Spr
gene id: 230844:Spr
uniprot id: A0A6I9M8H8
names: Similarity
messages: Belongs to the sepiapterin reductase family.

230844:Rev3l
gene id: 230844:Rev3l
uniprot id: A0A6I9LI90
uniprot id: A0A6J0DQQ2
uniprot id: A0A6J0DU18
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-B family.
messages: Nucleus

230844:LOC102926087
gene id: 230844:LOC102926087
uniprot id: A0A6I9MLR8
names: Cofactor
names: PTM
names: Similarity
messages: Belongs to the copper/topaquinone oxidase family.
messages: Contains 1 topaquinone per subunit.
messages: Topaquinone (TPQ) is generated by copper-dependent autoxidation of a specific tyrosyl residue.

230844:Sdr9c7
gene id: 230844:Sdr9c7
uniprot id: A0A6I9MLV3
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

230844:Mief1
gene id: 230844:Mief1
uniprot id: A0A6I9LA29
names: Subcellular Location Annotation
messages: Membrane
messages: Mitochondrion outer membrane

230844:Slc22a4
gene id: 230844:Slc22a4
uniprot id: A0A6I9MFL5
uniprot id: A0A6J0CNV5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Apical cell membrane
messages: Basal cell membrane
messages: Belongs to the major facilitator (TC 2.A.1) superfamily. Organic cation transporter (TC 2.A.1.19) family.
messages: Interacts with PDZK1.

230844:Atp7a
gene id: 230844:Atp7a
uniprot id: A0A6I9M9A1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Membrane
messages: trans-Golgi network membrane

230844:LOC102907711
gene id: 230844:LOC102907711
uniprot id: A0A6I9MJT4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

230844:Evpl
gene id: 230844:Evpl
uniprot id: A0A6I9MGH0
names: Similarity
messages: Belongs to the plakin or cytolinker family.

230844:Emc2
gene id: 230844:Emc2
uniprot id: A0A6I9LGE0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EMC2 family.
messages: Component of the ER membrane protein complex (EMC).
messages: Endoplasmic reticulum membrane
messages: Part of the endoplasmic reticulum membrane protein complex (EMC) that enables the energy-independent insertion into endoplasmic reticulum membranes of newly synthesized membrane proteins.

230844:Fam131a
gene id: 230844:Fam131a
uniprot id: A0A6I9M1A5
uniprot id: A0A6I9M5C8
names: Similarity
messages: Belongs to the FAM131 family.

230844:Lmx1a
gene id: 230844:Lmx1a
uniprot id: A0A6I9LGE3
names: Subcellular Location Annotation
messages: Nucleus

230844:Rnf170
gene id: 230844:Rnf170
uniprot id: A0A6J0DM45
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

230844:Mturn
gene id: 230844:Mturn
uniprot id: A0A6I9MDL2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MTURN family.
messages: Cytoplasm

230844:Slc25a12
gene id: 230844:Slc25a12
uniprot id: A0A6I9L6V6
uniprot id: A0A6J0CLF0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane
messages: Mitochondrion inner membrane

230844:LOC102923817
gene id: 230844:LOC102923817
uniprot id: A0A6I9LI23
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calycin superfamily. Lipocalin family.
messages: Functions as transport protein in the blood stream. Binds various ligands in the interior of its beta-barrel domain (By similarity). Appears to function in modulating the activity of the immune system during the acute-phase reaction.
messages: Secreted

230844:Pbx3
gene id: 230844:Pbx3
uniprot id: A0A6I9M3E6
uniprot id: A0A6J0E899
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TALE/PBX homeobox family.
messages: Nucleus

230844:LOC102909716
gene id: 230844:LOC102909716
uniprot id: A0A6I9LQD8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the intercrine beta (chemokine CC) family.
messages: Secreted

230844:Loxl4
gene id: 230844:Loxl4
uniprot id: A0A6I9LUB5
uniprot id: A0A6J0E956
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lysyl oxidase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mediates the post-translational oxidative deamination of lysine residues on target proteins leading to the formation of deaminated lysine (allysine).
messages: The lysine tyrosylquinone cross-link (LTQ) is generated by condensation of the epsilon-amino group of a lysine with a topaquinone produced by oxidation of tyrosine.
messages: extracellular space

230844:Midn
gene id: 230844:Midn
uniprot id: A0A6I9L6T9
uniprot id: A0A6I9LJP3
uniprot id: A0A6J0DBS3
names: Subcellular Location Annotation
messages: Nucleus

230844:Mtnr1b
gene id: 230844:Mtnr1b
uniprot id: A0A6I9M6I4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Hmgcs1
gene id: 230844:Hmgcs1
uniprot id: A0A6I9M3V1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the thiolase-like superfamily. HMG-CoA synthase family.
messages: Catalyzes the condensation of acetyl-CoA with acetoacetyl-CoA to form HMG-CoA.
messages: Homodimer.

230844:LOC102916970
gene id: 230844:LOC102916970
uniprot id: A0A6I9LV24
uniprot id: A0A6I9M3A4
uniprot id: A0A6J0E657
uniprot id: A0A6J0E7Y7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UDP-glycosyltransferase family.
messages: Membrane

230844:Fars2
gene id: 230844:Fars2
uniprot id: A0A6I9KXE5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Mitochondrion matrix

230844:Rps6ka1
gene id: 230844:Rps6ka1
uniprot id: A0A6I9L2Y9
uniprot id: A0A6J0D503
uniprot id: A0A6J0D5J1
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily.

230844:LOC102927822
gene id: 230844:LOC102927822
uniprot id: A0A6I9LLF2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Tlcd3b
gene id: 230844:Tlcd3b
uniprot id: A0A6I9LDA1
uniprot id: A0A6J0D786
names: Subcellular Location Annotation
messages: Membrane

230844:LOC102922596
gene id: 230844:LOC102922596
uniprot id: A0A6I9M0M7
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

230844:Leap2
gene id: 230844:Leap2
uniprot id: A0A6I9M4B4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LEAP2 family.
messages: Has an antimicrobial activity.
messages: Secreted

230844:Gnat2
gene id: 230844:Gnat2
uniprot id: A0A6I9LMM1
names: Similarity
messages: Belongs to the G-alpha family. G(i/o/t/z) subfamily.

230844:Cldn4
gene id: 230844:Cldn4
uniprot id: A0A6J0DP71
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

230844:Amigo3
gene id: 230844:Amigo3
uniprot id: A0A6I9L8D3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the immunoglobulin superfamily. AMIGO family.
messages: Membrane

230844:Pyroxd1
gene id: 230844:Pyroxd1
uniprot id: A0A6I9L4L7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. PYROXD1 subfamily.
messages: sarcomere

230844:Mlec
gene id: 230844:Mlec
uniprot id: A0A6I9MIH0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the malectin family.
messages: Endoplasmic reticulum membrane
messages: Membrane

230844:Cd200r1
gene id: 230844:Cd200r1
uniprot id: A0A6I9LEA8
names: Similarity
messages: Belongs to the CD200R family.

230844:Mme
gene id: 230844:Mme
uniprot id: A0A6J0CU67
names: Subcellular Location Annotation
messages: Membrane

230844:Igfbp6
gene id: 230844:Igfbp6
uniprot id: A0A6I9LFG1
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

230844:LOC107401155
gene id: 230844:LOC107401155
uniprot id: A0A6J0D5J8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

230844:Cibar2
gene id: 230844:Cibar2
uniprot id: A0A6J0E8C2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CIBAR family.
messages: centriole
messages: cilium basal body

230844:LOC102926593
gene id: 230844:LOC102926593
uniprot id: A0A6I9MDC4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:LOC102917596
gene id: 230844:LOC102917596
uniprot id: A0A6I9MBJ5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

230844:LOC102905710
gene id: 230844:LOC102905710
uniprot id: A0A6I9LY08
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

230844:Pot1
gene id: 230844:Pot1
uniprot id: A0A6I9M168
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the telombin family.
messages: Nucleus
messages: telomere

230844:Atp13a5
gene id: 230844:Atp13a5
uniprot id: A0A6I9L0J5
uniprot id: A0A6J0D5I8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily.
messages: Membrane

230844:Nanognb
gene id: 230844:Nanognb
uniprot id: A0A6J0CJ85
names: Subcellular Location Annotation
messages: Nucleus

230844:Emp1
gene id: 230844:Emp1
uniprot id: A0A6I9LC45
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PMP-22/EMP/MP20 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

230844:Psme4
gene id: 230844:Psme4
uniprot id: A0A6I9M513
names: Similarity
messages: Belongs to the BLM10 family.

230844:LOC102912928
gene id: 230844:LOC102912928
uniprot id: A0A6I9M7E9
uniprot id: A0A6J0ECC7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OXA1/ALB3/YidC family.
messages: Membrane

230844:LOC102915554
gene id: 230844:LOC102915554
uniprot id: A0A6J0CTT3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the immunoglobulin superfamily. BTN/MOG family.
messages: Membrane

230844:LOC102903936
gene id: 230844:LOC102903936
uniprot id: A0A6I9LIX5
uniprot id: A0A6J0DTM5
uniprot id: A0A6J0DUV1
uniprot id: A0A6J0DVL9
names: Subcellular Location Annotation
messages: Cytoplasm

230844:Smg8
gene id: 230844:Smg8
uniprot id: A0A6I9LGC7
names: Function
names: Similarity
messages: Belongs to the SMG8 family.
messages: Involved in nonsense-mediated decay (NMD) of mRNAs containing premature stop codons.

230844:Fam53c
gene id: 230844:Fam53c
uniprot id: A0A6I9LJ24
names: Similarity
messages: Belongs to the FAM53 family.

230844:LOC102920620
gene id: 230844:LOC102920620
uniprot id: A0A6I9MJ73
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calycin superfamily. Lipocalin family.
messages: Secreted

230844:Gngt1
gene id: 230844:Gngt1
uniprot id: A0A6I9LVM4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G protein gamma family.
messages: Cell membrane
messages: G proteins are composed of 3 units; alpha, beta and gamma.
messages: Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.
messages: Membrane

230844:Sparcl1
gene id: 230844:Sparcl1
uniprot id: A0A6I9LDH2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPARC family.
messages: extracellular matrix

230844:Rps23
gene id: 230844:Rps23
uniprot id: A0A6I9LCN8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Rough endoplasmic reticulum

230844:Chd2
gene id: 230844:Chd2
uniprot id: A0A6J0EEK3
uniprot id: A0A6J0EG82
names: Subcellular Location Annotation
messages: Nucleus

230844:Tmem231
gene id: 230844:Tmem231
uniprot id: A0A6I9KZS3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM231 family.
messages: Membrane
messages: Transmembrane component of the tectonic-like complex, a complex localized at the transition zone of primary cilia and acting as a barrier that prevents diffusion of transmembrane proteins between the cilia and plasma membranes. Required for ciliogenesis and sonic hedgehog/SHH signaling.
messages: cilium membrane

230844:Actg1
gene id: 230844:Actg1
uniprot id: A0A6I9LPF1
names: Similarity
messages: Belongs to the actin family.

230844:Gprin1
gene id: 230844:Gprin1
uniprot id: A0A6I9MHS7
names: Function
messages: May be involved in neurite outgrowth.

230844:Ssr2
gene id: 230844:Ssr2
uniprot id: A0A6I9L3I9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP-beta family.
messages: Endoplasmic reticulum membrane
messages: Heterotetramer of TRAP-alpha, TRAP-beta, TRAP-delta and TRAP-gamma.
messages: Membrane
messages: TRAP proteins are part of a complex whose function is to bind calcium to the ER membrane and thereby regulate the retention of ER resident proteins.

230844:Hspa2
gene id: 230844:Hspa2
uniprot id: A0A6I9L555
names: Similarity
messages: Belongs to the heat shock protein 70 family.

230844:Mdh1b
gene id: 230844:Mdh1b
uniprot id: A0A6I9L1P1
uniprot id: A0A6J0D1M8
uniprot id: A0A6J0D7G4
names: Similarity
messages: Belongs to the LDH/MDH superfamily. MDH type 2 family.

230844:Aspn
gene id: 230844:Aspn
uniprot id: A0A6I9M8L9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class I subfamily.
messages: extracellular matrix

230844:LOC102928657
gene id: 230844:LOC102928657
uniprot id: A0A6I9LGJ4
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

230844:Cel
gene id: 230844:Cel
uniprot id: A0A6I9LWD9
uniprot id: A0A6J0DWR6
names: Similarity
messages: Belongs to the type-B carboxylesterase/lipase family.

230844:LOC102914223
gene id: 230844:LOC102914223
uniprot id: A0A6I9LHW9
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

230844:Map2k2
gene id: 230844:Map2k2
uniprot id: A0A6I9LJJ0
names: Similarity
messages: Belongs to the protein kinase superfamily.

230844:Tenm1
gene id: 230844:Tenm1
uniprot id: A0A6I9LNC0
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tenascin family. Teneurin subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

230844:Fam83h
gene id: 230844:Fam83h
uniprot id: A0A6J0E4F1
names: Similarity
messages: Belongs to the FAM83 family.

230844:LOC102904606
gene id: 230844:LOC102904606
uniprot id: A0A6J0CGZ5
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

230844:Cct3
gene id: 230844:Cct3
uniprot id: A0A6I9L3K1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TCP-1 chaperonin family.
messages: Cytoplasm

230844:Cdk2ap2
gene id: 230844:Cdk2ap2
uniprot id: A0A6I9LL28
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDK2AP family.
messages: Nucleus

230844:LOC102923955
gene id: 230844:LOC102923955
uniprot id: A0A6I9M6Q1
names: Similarity
messages: Belongs to the cytochrome b5 family.

230844:Arl6
gene id: 230844:Arl6
uniprot id: A0A6I9LSR0
uniprot id: A0A6J0DIE3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Arf family.
messages: cilium membrane

230844:LOC102919209
gene id: 230844:LOC102919209
uniprot id: A0A6J0EBW3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistin/FIZZ family.
messages: Secreted

230844:LOC102909823
gene id: 230844:LOC102909823
uniprot id: A0A6I9LRQ6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a molecular chaperone for PCSK2/PC2, preventing its premature activation in the regulated secretory pathway. Binds to inactive PCSK2 in the endoplasmic reticulum and facilitates its transport from there to later compartments of the secretory pathway where it is proteolytically matured and activated. Also required for cleavage of PCSK2 but does not appear to be involved in its folding. Plays a role in regulating pituitary hormone secretion. The C-terminal peptide inhibits PCSK2 in vitro.
messages: Belongs to the 7B2 family.
messages: Interacts with PCSK2/PC2 early in the secretory pathway. Dissociation occurs at later stages.
messages: Secreted

230844:Wnt2b
gene id: 230844:Wnt2b
uniprot id: A0A6I9M2H7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

230844:Nav1
gene id: 230844:Nav1
uniprot id: A0A6I9LEV3
uniprot id: A0A6I9LUP1
uniprot id: A0A6J0DMZ4
uniprot id: A0A6J0DNA2
uniprot id: A0A6J0DNR8
uniprot id: A0A6J0DUI7
names: Similarity
messages: Belongs to the Nav/unc-53 family.

230844:Bche
gene id: 230844:Bche
uniprot id: A0A6I9L7D1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type-B carboxylesterase/lipase family.
messages: Secreted

230844:Ltb4r2
gene id: 230844:Ltb4r2
uniprot id: A0A6I9LQY4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

230844:Zfpm2
gene id: 230844:Zfpm2
uniprot id: A0A6I9L7R8
names: Subcellular Location Annotation
messages: Nucleus

230844:Adss2
gene id: 230844:Adss2
uniprot id: A0A6I9L006
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Mitochondrion
messages: Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP.
messages: Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis.

230844:Hoxa4
gene id: 230844:Hoxa4
uniprot id: A0A6I9LEF9
names: Subcellular Location Annotation
messages: Nucleus

230844:Gpt
gene id: 230844:Gpt
uniprot id: A0A6J0E478
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. Alanine aminotransferase subfamily.
messages: Homodimer.

230844:P4ha2
gene id: 230844:P4ha2
uniprot id: A0A6I9LZ15
uniprot id: A0A6J0DSP8
uniprot id: A0A6J0DU66
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P4HA family.
messages: Catalyzes the post-translational formation of 4-hydroxyproline in -Xaa-Pro-Gly- sequences in collagens and other proteins.
messages: Endoplasmic reticulum lumen

230844:Plcb3
gene id: 230844:Plcb3
uniprot id: A0A6I9LDA4
names: Cofactor
names: Function
messages: Binds 1 Ca(2+) ion per subunit.
messages: The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes.

230844:LOC102917945
gene id: 230844:LOC102917945
uniprot id: A0A6J0CZ16
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

230844:Rfx2
gene id: 230844:Rfx2
uniprot id: A0A6I9LEJ7
uniprot id: A0A6I9LPS6
uniprot id: A0A6J0DMK0
names: Subcellular Location Annotation
messages: Nucleus

230844:Amt
gene id: 230844:Amt
uniprot id: A0A6I9LJX6
uniprot id: A0A6J0DBP7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GcvT family.
messages: Mitochondrion
messages: The glycine cleavage system catalyzes the degradation of glycine.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

230844:Avpr2
gene id: 230844:Avpr2
uniprot id: A0A6I9M491
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily.
messages: Cell membrane
messages: Involved in renal water reabsorption. Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase.
messages: Membrane

230844:Clptm1l
gene id: 230844:Clptm1l
uniprot id: A0A6I9LYE3
uniprot id: A0A6I9M471
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CLPTM1 family.
messages: Membrane

230844:Adam28
gene id: 230844:Adam28
uniprot id: A0A6I9LPW8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

230844:Ranbp6
gene id: 230844:Ranbp6
uniprot id: A0A6I9L3C1
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

230844:Bax
gene id: 230844:Bax
uniprot id: A0A6J0E0T6
names: Similarity
messages: Belongs to the Bcl-2 family.

230844:LOC102913652
gene id: 230844:LOC102913652
uniprot id: A0A6J0CCR2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Sdhaf3
gene id: 230844:Sdhaf3
uniprot id: A0A6I9LMY8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I LYR family. SDHAF3 subfamily.
messages: Interacts with the iron-sulfur protein subunit within the SDH catalytic dimer.
messages: Mitochondrion matrix
messages: Plays an essential role in the assembly of succinate dehydrogenase (SDH), an enzyme complex (also referred to as respiratory complex II) that is a component of both the tricarboxylic acid (TCA) cycle and the mitochondrial electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Promotes maturation of the iron-sulfur protein subunit of the SDH catalytic dimer, protecting it from the deleterious effects of oxidants. May act together with SDHAF1.

230844:Dph1
gene id: 230844:Dph1
uniprot id: A0A6I9L594
names: Similarity
messages: Belongs to the DPH1/DPH2 family. DPH1 subfamily.

230844:Foxc2
gene id: 230844:Foxc2
uniprot id: A0A6I9MA13
names: Subcellular Location Annotation
messages: Nucleus

230844:Luc7l3
gene id: 230844:Luc7l3
uniprot id: A0A6I9KW32
uniprot id: A0A6J0E607
uniprot id: A0A6J0EDE3
names: Similarity
messages: Belongs to the Luc7 family.

230844:LOC102918150
gene id: 230844:LOC102918150
uniprot id: A0A6I9MCW6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Gcdh
gene id: 230844:Gcdh
uniprot id: A0A6I9MJI3
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

230844:LOC102907551
gene id: 230844:LOC102907551
uniprot id: A0A6I9LD36
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Ppp5c
gene id: 230844:Ppp5c
uniprot id: A0A6I9MCB0
names: Similarity
messages: Belongs to the PPP phosphatase family. PP-5 (PP-T) subfamily.

230844:Kcnk3
gene id: 230844:Kcnk3
uniprot id: A0A6I9MCH0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
messages: Membrane

230844:Nsfl1c
gene id: 230844:Nsfl1c
uniprot id: A0A6I9LKH0
uniprot id: A0A6I9LVU9
names: Subcellular Location Annotation
names: Subunit
messages: Golgi stack
messages: Part of a ternary complex containing STX5A, NSFL1C and VCP. NSFL1C forms a homotrimer that binds to one end of a VCP homohexamer. The complex binds to membranes enriched in phosphatidylethanolamine-containing lipids and promotes Golgi membrane fusion. Interaction with VCIP135 leads to dissociation of the complex via ATP hydrolysis by VCP. Binds ubiquitin and mono-ubiquitinated proteins via its N-terminal UBA-like domain when bound to VCP.

230844:P2ry6
gene id: 230844:P2ry6
uniprot id: A0A6I9LPI2
names: Subcellular Location Annotation
messages: Membrane

230844:Mgat1
gene id: 230844:Mgat1
uniprot id: A0A6J0DYM9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 13 family.
messages: Golgi apparatus membrane
messages: Initiates complex N-linked carbohydrate formation. Essential for the conversion of high-mannose to hybrid and complex N-glycans.
messages: Membrane
messages: The cofactor is mostly bound to the substrate.

230844:Rnf40
gene id: 230844:Rnf40
uniprot id: A0A6I9L4Q6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BRE1 family.
messages: Component of the RNF20/40 complex (also known as BRE1 complex) probably composed of 2 copies of RNF20/BRE1A and 2 copies of RNF40/BRE1B. Interacts with UBE2E1/UBCH6.
messages: Nucleus

230844:LOC102926167
gene id: 230844:LOC102926167
uniprot id: A0A6I9ME35
uniprot id: A0A6J0CJH8
names: Similarity
messages: Belongs to the serpin family.

230844:Nup85
gene id: 230844:Nup85
uniprot id: A0A6I9MDY6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the nucleoporin Nup85 family.
messages: Component of the nuclear pore complex (NPC).
messages: Functions as a component of the nuclear pore complex (NPC).
messages: Nucleus membrane
messages: nuclear pore complex

230844:Cpn1
gene id: 230844:Cpn1
uniprot id: A0A6I9MPQ2
names: Similarity
messages: Belongs to the peptidase M14 family.

230844:Numbl
gene id: 230844:Numbl
uniprot id: A0A6I9MFH8
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Plays a role in the process of neurogenesis.

230844:LOC102912416
gene id: 230844:LOC102912416
uniprot id: A0A6I9L5Q0
names: Similarity
messages: Belongs to the protein phosphatase inhibitor 2 family.

230844:Pde1b
gene id: 230844:Pde1b
uniprot id: A0A6I9LDL6
uniprot id: A0A6I9LTA4
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family. PDE1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

230844:Sypl1
gene id: 230844:Sypl1
uniprot id: A0A6I9MRF0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptophysin/synaptobrevin family.
messages: Membrane

230844:LOC102924790
gene id: 230844:LOC102924790
uniprot id: A0A6I9LTR2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome P450 family.
messages: Cytochromes P450 are a group of heme-thiolate monooxygenases.
messages: Endoplasmic reticulum membrane
messages: Microsome membrane

230844:Trim35
gene id: 230844:Trim35
uniprot id: A0A6I9M3G6
names: Subcellular Location Annotation
messages: Cytoplasm

230844:Kxd1
gene id: 230844:Kxd1
uniprot id: A0A6I9M2I8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KXD1 family.
messages: Lysosome membrane

230844:Taf1d
gene id: 230844:Taf1d
uniprot id: A0A6I9M6I2
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Component of the transcription factor SL1/TIF-IB complex, composed of TBP and at least TAF1A, TAF1B, TAF1C and TAF1D. Interacts with UBTF.
messages: Component of the transcription factor SL1/TIF-IB complex, which is involved in the assembly of the PIC (preinitiation complex) during RNA polymerase I-dependent transcription. The rate of PIC formation probably is primarily dependent on the rate of association of SL1/TIF-IB with the rDNA promoter. SL1/TIF-IB is involved in stabilization of nucleolar transcription factor 1/UBTF on rDNA. Formation of SL1/TIF-IB excludes the association of TBP with TFIID subunits.
messages: Nucleus

230844:Chd6
gene id: 230844:Chd6
uniprot id: A0A6I9L0M8
names: Similarity
messages: Belongs to the SNF2/RAD54 helicase family.

230844:LOC102928317
gene id: 230844:LOC102928317
uniprot id: A0A6I9MGL6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

230844:Olfm1
gene id: 230844:Olfm1
uniprot id: A0A6I9M5S4
uniprot id: A0A6J0CHD3
names: Subcellular Location Annotation
messages: Secreted
messages: Synapse

230844:Camk2g
gene id: 230844:Camk2g
uniprot id: A0A6J0E0R4
names: Similarity
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. CaMK subfamily.

230844:Ca5b
gene id: 230844:Ca5b
uniprot id: A0A6I9KY99
names: Function
names: Similarity
messages: Belongs to the alpha-carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

230844:LOC102907232
gene id: 230844:LOC102907232
uniprot id: A0A6I9LNE4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

230844:Styxl2
gene id: 230844:Styxl2
uniprot id: A0A6I9LTY3
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.

230844:Piezo2
gene id: 230844:Piezo2
uniprot id: A0A6J0DX45
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PIEZO (TC 1.A.75) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

230844:LOC102915444
gene id: 230844:LOC102915444
uniprot id: A0A6I9LCP8
names: Similarity
messages: Belongs to the cytochrome P450 family.

230844:Ccdc126
gene id: 230844:Ccdc126
uniprot id: A0A6J0EC58
names: Subcellular Location Annotation
messages: Secreted

230844:LOC102908319
gene id: 230844:LOC102908319
uniprot id: A0A6I9M6K5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Tmem258
gene id: 230844:Tmem258
uniprot id: A0A6J0CKD1
uniprot id: A0A6J0CMC2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OST5 family.
messages: Component of the oligosaccharyltransferase (OST) complex.
messages: Membrane
messages: Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All subunits are required for a maximal enzyme activity.

230844:Hmgcl
gene id: 230844:Hmgcl
uniprot id: A0A6I9LBQ2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HMG-CoA lyase family.
messages: Homodimer; disulfide-linked. Can also form homotetramers.
messages: Mitochondrial 3-hydroxymethyl-3-methylglutaryl-CoA lyase that catalyzes a cation-dependent cleavage of (S)-3-hydroxy-3-methylglutaryl-CoA into acetyl-CoA and acetoacetate, a key step in ketogenesis. Terminal step in leucine catabolism. Ketone bodies (beta-hydroxybutyrate, acetoacetate and acetone) are essential as an alternative source of energy to glucose, as lipid precursors and as regulators of metabolism.

230844:Prickle2
gene id: 230844:Prickle2
uniprot id: A0A6I9L3L4
uniprot id: A0A6J0CNA7
uniprot id: A0A6J0CNB6
names: Similarity
messages: Belongs to the prickle / espinas / testin family.

230844:Eif2a
gene id: 230844:Eif2a
uniprot id: A0A6I9M970
uniprot id: A0A6I9MG30
names: Function
names: Similarity
messages: Belongs to the WD repeat EIF2A family.
messages: Functions in the early steps of protein synthesis of a small number of specific mRNAs. Acts by directing the binding of methionyl-tRNAi to 40S ribosomal subunits. In contrast to the eIF-2 complex, it binds methionyl-tRNAi to 40S subunits in a codon-dependent manner, whereas the eIF-2 complex binds methionyl-tRNAi to 40S subunits in a GTP-dependent manner.

230844:Prkab1
gene id: 230844:Prkab1
uniprot id: A0A6I9L338
names: Function
names: Similarity
messages: Belongs to the 5'-AMP-activated protein kinase beta subunit family.
messages: Non-catalytic subunit of AMP-activated protein kinase (AMPK), an energy sensor protein kinase that plays a key role in regulating cellular energy metabolism. In response to reduction of intracellular ATP levels, AMPK activates energy-producing pathways and inhibits energy-consuming processes: inhibits protein, carbohydrate and lipid biosynthesis, as well as cell growth and proliferation. AMPK acts via direct phosphorylation of metabolic enzymes, and by longer-term effects via phosphorylation of transcription regulators. Also acts as a regulator of cellular polarity by remodeling the actin cytoskeleton; probably by indirectly activating myosin. Beta non-catalytic subunit acts as a scaffold on which the AMPK complex assembles, via its C-terminus that bridges alpha (PRKAA1 or PRKAA2) and gamma subunits (PRKAG1, PRKAG2 or PRKAG3).

230844:Ndst1
gene id: 230844:Ndst1
uniprot id: A0A6I9LV55
uniprot id: A0A6J0DTB5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 1 family. NDST subfamily.
messages: Membrane

230844:Mllt11
gene id: 230844:Mllt11
uniprot id: A0A6J0DNJ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MLLT11 family.
messages: Nucleus
messages: centrosome

230844:Pcbd1
gene id: 230844:Pcbd1
uniprot id: A0A6I9L7G0
names: Similarity
messages: Belongs to the pterin-4-alpha-carbinolamine dehydratase family.

230844:LOC102924842
gene id: 230844:LOC102924842
uniprot id: A0A6I9L5R3
uniprot id: A0A6I9LD37
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Inflammasome

230844:Gcg
gene id: 230844:Gcg
uniprot id: A0A6I9LYL4
names: Similarity
messages: Belongs to the glucagon family.

230844:Ssrp1
gene id: 230844:Ssrp1
uniprot id: A0A6I9LXE2
uniprot id: A0A6I9M4Y9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SSRP1 family.
messages: Chromosome
messages: Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment of the nucleosome following the passage of RNA polymerase II.
messages: Nucleus

230844:Dtd2
gene id: 230844:Dtd2
uniprot id: A0A6I9L279
names: Similarity
messages: Belongs to the DTD family.

230844:Fam168b
gene id: 230844:Fam168b
uniprot id: A0A6I9M603
uniprot id: A0A6I9MA65
uniprot id: A0A6J0E8G4
uniprot id: A0A6J0ECL3
names: Similarity
messages: Belongs to the FAM168 family.

230844:Nol12
gene id: 230844:Nol12
uniprot id: A0A6I9L9Z4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RRP17 family.
messages: Interacts with KIAA1191.
messages: nucleolus

230844:Gfod1
gene id: 230844:Gfod1
uniprot id: A0A6I9L7P2
names: Similarity
messages: Belongs to the Gfo/Idh/MocA family.

230844:Prpf18
gene id: 230844:Prpf18
uniprot id: A0A6I9LL86
uniprot id: A0A6I9LWH7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRP18 family.
messages: Nucleus speckle

230844:LOC102917993
gene id: 230844:LOC102917993
uniprot id: A0A6I9M712
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

230844:Tnfsf13b
gene id: 230844:Tnfsf13b
uniprot id: A0A6J0DK93
names: Similarity
messages: Belongs to the tumor necrosis factor family.

230844:Kif24
gene id: 230844:Kif24
uniprot id: A0A6J0DX79
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

230844:Sox4
gene id: 230844:Sox4
uniprot id: A0A6J0CHP2
names: Subcellular Location Annotation
messages: Nucleus

230844:LOC102908216
gene id: 230844:LOC102908216
uniprot id: A0A6I9MC03
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:LOC102910427
gene id: 230844:LOC102910427
uniprot id: A0A6I9L0T8
names: Similarity
messages: Belongs to the intercrine gamma family.

230844:LOC102904812
gene id: 230844:LOC102904812
uniprot id: A0A6I9L5G9
names: Similarity
messages: Belongs to the cytochrome P450 family.

230844:Gsdmd
gene id: 230844:Gsdmd
uniprot id: A0A6J0EBU0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gasdermin family.
messages: Cell membrane
messages: Membrane
messages: cytosol

230844:Prkca
gene id: 230844:Prkca
uniprot id: A0A6J0D354
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.
messages: Binds 3 Ca(2+) ions per subunit. The ions are bound to the C2 domain.
messages: Cell membrane
messages: Cytoplasm
messages: Membrane
messages: Mitochondrion membrane
messages: Nucleus

230844:LOC121820827
gene id: 230844:LOC121820827
uniprot id: A0A6I9LPN0
names: Similarity
messages: Belongs to the aldo/keto reductase family.

230844:LOC102924344
gene id: 230844:LOC102924344
uniprot id: A0A6I9LKU6
names: Subcellular Location Annotation
messages: Membrane

230844:C20H8orf33
gene id: 230844:C20H8orf33
uniprot id: A0A6I9MHP6
names: Similarity
messages: Belongs to the UPF0488 family.

230844:Vwc2
gene id: 230844:Vwc2
uniprot id: A0A6I9L866
names: Subcellular Location Annotation
messages: Synapse

230844:Atp4a
gene id: 230844:Atp4a
uniprot id: A0A6I9LFU9
names: Similarity
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIC subfamily.
messages: Cell membrane
messages: Membrane

230844:C23H12orf43
gene id: 230844:C23H12orf43
uniprot id: A0A6I9MBB4
uniprot id: A0A6I9MFF0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CUSTOS family.
messages: Nucleus envelope

230844:LOC102903725
gene id: 230844:LOC102903725
uniprot id: A0A6J0DM86
uniprot id: A0A6J0DQD7
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

230844:Tlr2
gene id: 230844:Tlr2
uniprot id: A0A6I9LUV7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Toll-like receptor family.
messages: Cooperates with LY96 to mediate the innate immune response to bacterial lipoproteins and other microbial cell wall components. Cooperates with TLR1 or TLR6 to mediate the innate immune response to bacterial lipoproteins or lipopeptides. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response.
messages: Membrane

230844:LOC102906757
gene id: 230844:LOC102906757
uniprot id: A0A6I9L116
names: Function
names: Similarity
messages: Belongs to the TYW1 family.
messages: Probable component of the wybutosine biosynthesis pathway. Wybutosine is a hyper modified guanosine with a tricyclic base found at the 3'-position adjacent to the anticodon of eukaryotic phenylalanine tRNA. Catalyzes the condensation of N-methylguanine with 2 carbon atoms from pyruvate to form the tricyclic 4-demethylwyosine, an intermediate in wybutosine biosynthesis.

230844:Aacs
gene id: 230844:Aacs
uniprot id: A0A6I9KZT9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP-dependent AMP-binding enzyme family.
messages: Converts acetoacetate to acetoacetyl-CoA in the cytosol.
messages: cytosol

230844:Dlx1
gene id: 230844:Dlx1
uniprot id: A0A6I9L3M1
names: Subcellular Location Annotation
messages: Nucleus

230844:Ino80c
gene id: 230844:Ino80c
uniprot id: A0A6I9LKA2
names: Subcellular Location Annotation
messages: Nucleus

230844:Slc25a53
gene id: 230844:Slc25a53
uniprot id: A0A6J0CJ98
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

230844:Ptov1
gene id: 230844:Ptov1
uniprot id: A0A6I9LLU8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activates transcription. Required for nuclear translocation of FLOT1. Promotes cell proliferation.
messages: Belongs to the Mediator complex subunit 25 family. PTOV1 subfamily.
messages: Cell membrane
messages: Cytoplasm
messages: May interact with CREBBP. Interacts with FLOT1.
messages: Nucleus
messages: perinuclear region

230844:Tnrc6c
gene id: 230844:Tnrc6c
uniprot id: A0A6I9LTU4
names: Similarity
messages: Belongs to the GW182 family.

230844:Scrn2
gene id: 230844:Scrn2
uniprot id: A0A6J0EBG7
names: Similarity
messages: Belongs to the peptidase C69 family. Secernin subfamily.

230844:Prkci
gene id: 230844:Prkci
uniprot id: A0A6J0DJX6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.
messages: Cytoplasm
messages: Endosome

230844:Ergic1
gene id: 230844:Ergic1
uniprot id: A0A6I9L812
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ERGIC family.
messages: Endoplasmic reticulum membrane
messages: Endoplasmic reticulum-Golgi intermediate compartment membrane
messages: Golgi apparatus membrane
messages: Plays a role in transport between endoplasmic reticulum and Golgi.

230844:LOC102910385
gene id: 230844:LOC102910385
uniprot id: A0A6I9M016
names: Similarity
messages: Belongs to the aldo/keto reductase family.

230844:Jag1
gene id: 230844:Jag1
uniprot id: A0A6J0DR41
names: Caution
names: Function
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Putative Notch ligand involved in the mediation of Notch signaling.

230844:LOC102912233
gene id: 230844:LOC102912233
uniprot id: A0A6J0CSH5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Pttg1
gene id: 230844:Pttg1
uniprot id: A0A6I9L507
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the securin family.
messages: Cytoplasm
messages: Nucleus

230844:Rxfp4
gene id: 230844:Rxfp4
uniprot id: A0A6I9MB65
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

230844:Wasf2
gene id: 230844:Wasf2
uniprot id: A0A6I9LA78
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SCAR/WAVE family.
messages: Binds actin and the Arp2/3 complex.
messages: Downstream effector molecule involved in the transmission of signals from tyrosine kinase receptors and small GTPases to the actin cytoskeleton. Promotes formation of actin filaments. Part of the WAVE complex that regulates lamellipodia formation. The WAVE complex regulates actin filament reorganization via its interaction with the Arp2/3 complex.
messages: cytoskeleton

230844:Ahcyl1
gene id: 230844:Ahcyl1
uniprot id: A0A6I9LMN8
names: Similarity
messages: Belongs to the adenosylhomocysteinase family.

230844:Sost
gene id: 230844:Sost
uniprot id: A0A6I9KZS0
names: Similarity
messages: Belongs to the sclerostin family.

230844:Derl1
gene id: 230844:Derl1
uniprot id: A0A6I9M5J1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the derlin family.
messages: Endoplasmic reticulum membrane
messages: Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome.
messages: Membrane

230844:LOC102924000
gene id: 230844:LOC102924000
uniprot id: A0A6I9L577
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Natd1
gene id: 230844:Natd1
uniprot id: A0A6I9L633
names: Similarity
messages: Belongs to the NATD1 family.

230844:Krt1
gene id: 230844:Krt1
uniprot id: A0A6I9LP06
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the intermediate filament family.
messages: Cell membrane
messages: Cytoplasm
messages: Membrane

230844:Kif1c
gene id: 230844:Kif1c
uniprot id: A0A6I9MC61
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

230844:Mitf
gene id: 230844:Mitf
uniprot id: A0A6I9KX30
uniprot id: A0A6I9L3W9
uniprot id: A0A6J0CP85
uniprot id: A0A6J0CQI9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MiT/TFE family.
messages: Nucleus

230844:LOC102921668
gene id: 230844:LOC102921668
uniprot id: A0A6J0E857
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 6 family.
messages: Membrane

230844:Gpha2
gene id: 230844:Gpha2
uniprot id: A0A6I9LKJ0
names: Similarity
messages: Belongs to the glycoprotein hormones subunit alpha family.

230844:Dysf
gene id: 230844:Dysf
uniprot id: A0A6I9LW41
uniprot id: A0A6I9LW46
uniprot id: A0A6I9M1X3
uniprot id: A0A6I9M1X7
uniprot id: A0A6I9M1Y2
uniprot id: A0A6I9M743
uniprot id: A0A6I9M749
uniprot id: A0A6I9M754
uniprot id: A0A6I9M8G0
uniprot id: A0A6I9M8G5
uniprot id: A0A6I9M8H3
uniprot id: A0A6I9MCD2
uniprot id: A0A6I9MCD6
uniprot id: A0A6I9MCE1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferlin family.
messages: Cytoplasmic vesicle membrane
messages: Membrane

230844:Lyzl6
gene id: 230844:Lyzl6
uniprot id: A0A6J0DAS7
names: Similarity
messages: Belongs to the glycosyl hydrolase 22 family.

230844:Steap1
gene id: 230844:Steap1
uniprot id: A0A6I9M420
names: Subcellular Location Annotation
messages: Membrane

230844:Cadm2
gene id: 230844:Cadm2
uniprot id: A0A6I9M0Q1
uniprot id: A0A6I9M7K0
uniprot id: A0A6J0E8Z2
names: Similarity
messages: Belongs to the nectin family.

230844:Pfdn2
gene id: 230844:Pfdn2
uniprot id: A0A6I9MAV5
names: Function
names: Similarity
messages: Belongs to the prefoldin subunit beta family.
messages: Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins.

230844:Smc1b
gene id: 230844:Smc1b
uniprot id: A0A6I9LJL0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SMC family. SMC1 subfamily.
messages: Chromosome
messages: Nucleus

230844:Cysltr1
gene id: 230844:Cysltr1
uniprot id: A0A6J0CIZ0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

230844:Pus3
gene id: 230844:Pus3
uniprot id: A0A6I9LJN0
names: Similarity
messages: Belongs to the tRNA pseudouridine synthase TruA family.

230844:Mgmt
gene id: 230844:Mgmt
uniprot id: A0A6I9LSQ2
uniprot id: A0A6J0E4R2
names: Function
names: Similarity
messages: Belongs to the MGMT family.
messages: Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.

230844:Grik2
gene id: 230844:Grik2
uniprot id: A0A6I9LHD1
uniprot id: A0A6J0DPF5
uniprot id: A0A6J0DS83
uniprot id: A0A6J0DSI3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Receptor for glutamate that functions as a ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system.

230844:Uba3
gene id: 230844:Uba3
uniprot id: A0A6I9L3W7
uniprot id: A0A6J0CQF2
names: Function
names: Similarity
messages: Belongs to the ubiquitin-activating E1 family. UBA3 subfamily.
messages: Catalytic subunit of the dimeric E1 enzyme, which activates NEDD8.

230844:LOC102909762
gene id: 230844:LOC102909762
uniprot id: A0A6I9LY04
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Cdpf1
gene id: 230844:Cdpf1
uniprot id: A0A6J0CVY1
names: Similarity
messages: Belongs to the CDPF1 family.

230844:Vipr1
gene id: 230844:Vipr1
uniprot id: A0A6I9LFS0
uniprot id: A0A6I9LVK3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 2 family.
messages: Cell membrane
messages: Membrane

230844:Kdm6b
gene id: 230844:Kdm6b
uniprot id: A0A6I9L948
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UTX family.
messages: Nucleus

230844:Flot2
gene id: 230844:Flot2
uniprot id: A0A6I9L6N1
uniprot id: A0A6I9LE93
uniprot id: A0A6J0D818
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the band 7/mec-2 family. Flotillin subfamily.
messages: Cell membrane
messages: Endosome
messages: Heterooligomeric complex of flotillin-1 and flotillin-2 and caveolin-1 and caveolin-2. Interacts with ECPAS.
messages: Heterooligomeric complex.
messages: May act as a scaffolding protein within caveolar membranes, functionally participating in formation of caveolae or caveolae-like vesicles.
messages: Membrane
messages: Membrane raft
messages: caveola

230844:Cd3e
gene id: 230844:Cd3e
uniprot id: A0A6I9M5D3
names: Subcellular Location Annotation
messages: Membrane

230844:Serpini1
gene id: 230844:Serpini1
uniprot id: A0A6I9L7D6
names: Similarity
messages: Belongs to the serpin family.

230844:Nkx3-1
gene id: 230844:Nkx3-1
uniprot id: A0A6I9LM55
names: Subcellular Location Annotation
messages: Nucleus

230844:Dusp9
gene id: 230844:Dusp9
uniprot id: A0A6J0CEE6
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.

230844:Septin10
gene id: 230844:Septin10
uniprot id: A0A6J0CT24
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.
messages: Filament-forming cytoskeletal GTPase.
messages: Septins polymerize into heterooligomeric protein complexes that form filaments.

230844:LOC102912901
gene id: 230844:LOC102912901
uniprot id: A0A6J0DRF9
names: Subcellular Location Annotation
messages: Nucleus

230844:Actl9
gene id: 230844:Actl9
uniprot id: A0A6I9M096
names: Similarity
messages: Belongs to the actin family.

230844:Adgra3
gene id: 230844:Adgra3
uniprot id: A0A6I9LEZ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 2 family. Adhesion G-protein coupled receptor (ADGR) subfamily.
messages: Membrane

230844:LOC102920506
gene id: 230844:LOC102920506
uniprot id: A0A6I9ML30
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:LOC102905692
gene id: 230844:LOC102905692
uniprot id: A0A6I9LAY6
names: Function
names: Similarity
messages: Belongs to the PET191 family.
messages: Involved in an early step of the mitochondrial complex IV assembly process.

230844:Brinp2
gene id: 230844:Brinp2
uniprot id: A0A6J0CYX0
names: Similarity
messages: Belongs to the BRINP family.

230844:Phyhipl
gene id: 230844:Phyhipl
uniprot id: A0A6I9LH35
uniprot id: A0A6I9LLJ6
names: Similarity
messages: Belongs to the PHYHIP family.

230844:Cdt1
gene id: 230844:Cdt1
uniprot id: A0A6I9M4J5
names: Similarity
messages: Belongs to the Cdt1 family.

230844:Pdcl2
gene id: 230844:Pdcl2
uniprot id: A0A6I9LID6
names: Similarity
messages: Belongs to the phosducin family.

230844:Hbegf
gene id: 230844:Hbegf
uniprot id: A0A6J0EAL7
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

230844:Agk
gene id: 230844:Agk
uniprot id: A0A6I9MHV7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AGK family.
messages: Membrane
messages: Mitochondrion inner membrane
messages: Mitochondrion intermembrane space

230844:Akr1d1
gene id: 230844:Akr1d1
uniprot id: A0A6J0CQV4
names: Similarity
messages: Belongs to the aldo/keto reductase family.

230844:Fgf5
gene id: 230844:Fgf5
uniprot id: A0A6I9LDD6
uniprot id: A0A6J0D495
names: Similarity
messages: Belongs to the heparin-binding growth factors family.

230844:Iqsec2
gene id: 230844:Iqsec2
uniprot id: A0A6I9MEQ9
uniprot id: A0A6J0CJM8
uniprot id: A0A6J0CK91
uniprot id: A0A6J0CKV4
uniprot id: A0A6J0CMW3
names: Similarity
messages: Belongs to the BRAG family.

230844:Mocs1
gene id: 230844:Mocs1
uniprot id: A0A6I9MFJ5
names: Similarity
messages: In the C-terminal section; belongs to the MoaC family.
messages: In the N-terminal section; belongs to the radical SAM superfamily. MoaA family.

230844:Samm50
gene id: 230844:Samm50
uniprot id: A0A6I9LC75
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SAM50/omp85 family.
messages: Mitochondrion outer membrane

230844:LOC102908463
gene id: 230844:LOC102908463
uniprot id: A0A6I9MKM0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Epb41
gene id: 230844:Epb41
uniprot id: A0A6I9L254
uniprot id: A0A6I9L2U7
uniprot id: A0A6J0D391
uniprot id: A0A6J0D4U4
uniprot id: A0A6J0D4V0
uniprot id: A0A6J0D5D0
uniprot id: A0A6J0D5D9
uniprot id: A0A6J0D962
uniprot id: A0A6J0D967
names: Subcellular Location Annotation
messages: Nucleus
messages: cell cortex
messages: cytoskeleton

230844:Thada
gene id: 230844:Thada
uniprot id: A0A6J0EDH3
names: Function
names: Similarity
messages: Belongs to the THADA family.
messages: Together with methyltransferase FTSJ1, methylates the 2'-O-ribose of nucleotides at position 32 of the anticodon loop of substrate tRNAs.

230844:Stoml1
gene id: 230844:Stoml1
uniprot id: A0A6I9KUU3
uniprot id: A0A6J0DWU3
names: Similarity
messages: Belongs to the band 7/mec-2 family.

230844:LOC102925212
gene id: 230844:LOC102925212
uniprot id: A0A6I9M9L3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nonaspanin (TM9SF) (TC 9.A.2) family.
messages: Membrane

230844:LOC102909010
gene id: 230844:LOC102909010
uniprot id: A0A6I9LTJ8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associates with the pre-60S ribosomal particle.
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Component of the ribosome assembly machinery. Nuclear paralog of the ribosomal protein P0, it binds pre-60S subunits at an early stage of assembly in the nucleolus, and is replaced by P0 in cytoplasmic pre-60S subunits and mature 80S ribosomes.
messages: Cytoplasm
messages: nucleolus

230844:Tacr3
gene id: 230844:Tacr3
uniprot id: A0A6I9KSL6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Hmcn2
gene id: 230844:Hmcn2
uniprot id: A0A6J0DNI9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

230844:LOC102916661
gene id: 230844:LOC102916661
uniprot id: A0A6I9M593
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:LOC102916043
gene id: 230844:LOC102916043
uniprot id: A0A6I9M4J1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Tmem254
gene id: 230844:Tmem254
uniprot id: A0A6I9M263
uniprot id: A0A6I9M8S6
names: Subcellular Location Annotation
messages: Membrane

230844:Ninj1
gene id: 230844:Ninj1
uniprot id: A0A6I9LXP2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ninjurin family.
messages: Membrane

230844:Tdrd3
gene id: 230844:Tdrd3
uniprot id: A0A6I9LA22
uniprot id: A0A6J0D3Z7
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus
messages: Scaffolding protein that specifically recognizes and binds dimethylarginine-containing proteins. Plays a role in the regulation of translation of target mRNAs by binding Arg/Gly-rich motifs (GAR) in dimethylarginine-containing proteins. In nucleus, acts as a coactivator: recognizes and binds asymmetric dimethylation on the core histone tails associated with transcriptional activation (H3R17me2a and H4R3me2a) and recruits proteins at these arginine-methylated loci. In cytoplasm, acts as an antiviral factor that participates in the assembly of stress granules together with G3BP1.

230844:Ubl4a
gene id: 230844:Ubl4a
uniprot id: A0A6I9M465
names: Subcellular Location Annotation
messages: cytosol

230844:Ankzf1
gene id: 230844:Ankzf1
uniprot id: A0A6J0CEG9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ANKZF1/VMS1 family.
messages: Cytoplasm

230844:LOC102906775
gene id: 230844:LOC102906775
uniprot id: A0A6I9KZD3
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

230844:Gbx1
gene id: 230844:Gbx1
uniprot id: A0A6I9M998
names: Subcellular Location Annotation
messages: Nucleus

230844:LOC102928070
gene id: 230844:LOC102928070
uniprot id: A0A6I9KW42
names: Similarity
messages: Belongs to the NDK family.

230844:Tor1a
gene id: 230844:Tor1a
uniprot id: A0A6I9LIK9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ClpA/ClpB family. Torsin subfamily.
messages: Endoplasmic reticulum lumen

230844:Grpel2
gene id: 230844:Grpel2
uniprot id: A0A6I9LZQ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GrpE family.
messages: Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner.
messages: Mitochondrion matrix

230844:Nrcam
gene id: 230844:Nrcam
uniprot id: A0A6I9LX01
uniprot id: A0A6I9M359
uniprot id: A0A6I9M4M8
uniprot id: A0A6J0E4Q3
uniprot id: A0A6J0E4Q7
uniprot id: A0A6J0E4R0
uniprot id: A0A6J0E4R5
uniprot id: A0A6J0E4R9
uniprot id: A0A6J0E6K2
uniprot id: A0A6J0E6K8
uniprot id: A0A6J0E6L4
uniprot id: A0A6J0E6L8
uniprot id: A0A6J0E8A7
uniprot id: A0A6J0E8B3
uniprot id: A0A6J0E8C1
uniprot id: A0A6J0E8C5
uniprot id: A0A6J0EAH7
uniprot id: A0A6J0EAI1
uniprot id: A0A6J0EAI8
uniprot id: A0A6J0EAJ3
uniprot id: A0A6J0EC77
uniprot id: A0A6J0EC82
uniprot id: A0A6J0EC88
uniprot id: A0A6J0EC93
names: Similarity
messages: Belongs to the immunoglobulin superfamily. L1/neurofascin/NgCAM family.

230844:Fyn
gene id: 230844:Fyn
uniprot id: A0A6I9LKC0
uniprot id: A0A6I9LSL1
names: Similarity
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.

230844:Glis3
gene id: 230844:Glis3
uniprot id: A0A6I9LZE3
uniprot id: A0A6J0E2T5
names: Similarity
messages: Belongs to the GLI C2H2-type zinc-finger protein family.

230844:Ak5
gene id: 230844:Ak5
uniprot id: A0A6I9M4P7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenylate kinase family.
messages: Cytoplasm

230844:Onecut1
gene id: 230844:Onecut1
uniprot id: A0A6I9L9U1
uniprot id: A0A6J0CYQ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CUT homeobox family.
messages: Nucleus

230844:Gpx2
gene id: 230844:Gpx2
uniprot id: A0A6I9KXY1
names: Similarity
messages: Belongs to the glutathione peroxidase family.

230844:LOC102918597
gene id: 230844:LOC102918597
uniprot id: A0A6J0DU61
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:LOC102917539
gene id: 230844:LOC102917539
uniprot id: A0A6J0CU74
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

230844:Pex5
gene id: 230844:Pex5
uniprot id: A0A6I9M344
uniprot id: A0A6I9M866
uniprot id: A0A6J0CEX2
uniprot id: A0A6J0CFB0
names: Similarity
messages: Belongs to the peroxisomal targeting signal receptor family.

230844:Cflar
gene id: 230844:Cflar
uniprot id: A0A6I9L1A3
uniprot id: A0A6J0D7M1
names: Similarity
messages: Belongs to the peptidase C14A family.

230844:LOC102912449
gene id: 230844:LOC102912449
uniprot id: A0A6I9M9Z3
names: Similarity
messages: Belongs to the type-B carboxylesterase/lipase family.

230844:Celf1
gene id: 230844:Celf1
uniprot id: A0A6I9LID2
uniprot id: A0A6I9LY76
uniprot id: A0A6J0DR17
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CELF/BRUNOL family.
messages: Cytoplasm
messages: Nucleus

230844:Elf4
gene id: 230844:Elf4
uniprot id: A0A6I9MKF1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

230844:Dclk3
gene id: 230844:Dclk3
uniprot id: A0A6I9LA04
names: Similarity
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. CaMK subfamily.

230844:Fam174c
gene id: 230844:Fam174c
uniprot id: A0A6I9L845
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAM174 family.
messages: Membrane

230844:Dnah8
gene id: 230844:Dnah8
uniprot id: A0A6I9LQ68
names: Similarity
messages: Belongs to the dynein heavy chain family.

230844:Stmn2
gene id: 230844:Stmn2
uniprot id: A0A6I9LEX5
names: Similarity
messages: Belongs to the stathmin family.

230844:Usp5
gene id: 230844:Usp5
uniprot id: A0A6I9M362
uniprot id: A0A6I9M9Q7
names: Function
names: Similarity
messages: Belongs to the peptidase C19 family.
messages: Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes.

230844:LOC102916067
gene id: 230844:LOC102916067
uniprot id: A0A6I9MGH1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Apc2
gene id: 230844:Apc2
uniprot id: A0A6I9LJN2
uniprot id: A0A6J0D9W4
uniprot id: A0A6J0DBQ6
uniprot id: A0A6J0DGR9
names: Similarity
messages: Belongs to the adenomatous polyposis coli (APC) family.

230844:Fut11
gene id: 230844:Fut11
uniprot id: A0A6I9LUG6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 10 family.
messages: Golgi stack membrane
messages: Membrane
messages: Predominantly fucosylates the innermost N-acetyl glucosamine (GlcNAc) residue in biantennary N-glycan acceptors.

230844:Rara
gene id: 230844:Rara
uniprot id: A0A6I9KVS9
uniprot id: A0A6I9L5G6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR1 subfamily.
messages: Nucleus

230844:Coq7
gene id: 230844:Coq7
uniprot id: A0A6I9LND7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the COQ7 family.
messages: Binds 2 iron ions per subunit.
messages: Catalyzes the hydroxylation of 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) during ubiquinone biosynthesis. Has also a structural role in the COQ enzyme complex, stabilizing other COQ polypeptides. Involved in lifespan determination in a ubiquinone-independent manner.
messages: Component of a multi-subunit COQ enzyme complex, composed of at least COQ3, COQ4, COQ5, COQ6, COQ7 and COQ9. Interacts with ADCK4 and COQ6. Interacts with COQ9.
messages: Mitochondrion inner membrane

230844:Rps6
gene id: 230844:Rps6
uniprot id: A0A6I9LB12
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS6 family.

230844:Actr8
gene id: 230844:Actr8
uniprot id: A0A6I9LM10
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the actin family. ARP8 subfamily.
messages: Chromosome
messages: Component of the chromatin remodeling INO80 complex; specifically part of a complex module associated with the DBINO domain of INO80. Exists as monomers and dimers, but the dimer is most probably the biologically relevant form required for stable interactions with histones that exploits the twofold symmetry of the nucleosome core.
messages: Nucleus
messages: Plays an important role in the functional organization of mitotic chromosomes. Exhibits low basal ATPase activity, and unable to polymerize.
messages: Proposed core component of the chromatin remodeling INO80 complex which is involved in transcriptional regulation, DNA replication and probably DNA repair.

230844:Dact3
gene id: 230844:Dact3
uniprot id: A0A6J0EBV8
names: Similarity
messages: Belongs to the dapper family.

230844:Myh14
gene id: 230844:Myh14
uniprot id: A0A6I9LXB3
uniprot id: A0A6I9M232
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.

230844:Kcnn4
gene id: 230844:Kcnn4
uniprot id: A0A6I9MAK7
names: Subcellular Location Annotation
messages: Membrane

230844:LOC102904532
gene id: 230844:LOC102904532
uniprot id: A0A6I9MFM9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Zkscan1
gene id: 230844:Zkscan1
uniprot id: A0A6I9KU91
uniprot id: A0A6I9L0Z0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the krueppel C2H2-type zinc-finger protein family.
messages: Nucleus

230844:LOC102906938
gene id: 230844:LOC102906938
uniprot id: A0A6I9LIY3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:LOC102909129
gene id: 230844:LOC102909129
uniprot id: A0A6I9LXQ2
names: Similarity
messages: Belongs to the SNF7 family.

230844:Ptk2
gene id: 230844:Ptk2
uniprot id: A0A6J0E3Z1
uniprot id: A0A6J0E5Q6
uniprot id: A0A6J0E7E0
uniprot id: A0A6J0E7E4
uniprot id: A0A6J0E7F1
uniprot id: A0A6J0E9H8
uniprot id: A0A6J0E9I6
uniprot id: A0A6J0E9J3
uniprot id: A0A6J0EBH7
uniprot id: A0A6J0EBI0
names: Subcellular Location Annotation
messages: Cell membrane
messages: cell cortex
messages: focal adhesion

230844:LOC102908784
gene id: 230844:LOC102908784
uniprot id: A0A6I9LNE9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Gng12
gene id: 230844:Gng12
uniprot id: A0A6J0E6N4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G protein gamma family.
messages: Cell membrane
messages: G proteins are composed of 3 units; alpha, beta and gamma.
messages: Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.
messages: Membrane

230844:P3h1
gene id: 230844:P3h1
uniprot id: A0A6I9M9R5
names: Similarity
messages: Belongs to the leprecan family.

230844:LOC102903479
gene id: 230844:LOC102903479
uniprot id: A0A6I9ME08
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Entpd3
gene id: 230844:Entpd3
uniprot id: A0A6I9MDA5
names: Similarity
messages: Belongs to the GDA1/CD39 NTPase family.

230844:LOC102923525
gene id: 230844:LOC102923525
uniprot id: A0A6I9LMI0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

230844:Zic3
gene id: 230844:Zic3
uniprot id: A0A6I9M2Y2
uniprot id: A0A6I9M823
names: Similarity
messages: Belongs to the GLI C2H2-type zinc-finger protein family.

230844:Krt20
gene id: 230844:Krt20
uniprot id: A0A6I9KVE3
names: Similarity
messages: Belongs to the intermediate filament family.

230844:Mcf2l
gene id: 230844:Mcf2l
uniprot id: A0A6J0DHG7
uniprot id: A0A6J0DJW1
uniprot id: A0A6J0DJY4
uniprot id: A0A6J0DK58
uniprot id: A0A6J0DQV9
names: Subcellular Location Annotation
messages: Cytoplasm

230844:Sdr42e1
gene id: 230844:Sdr42e1
uniprot id: A0A6I9LM42
names: Similarity
messages: Belongs to the 3-beta-HSD family.

230844:LOC102904901
gene id: 230844:LOC102904901
uniprot id: A0A6I9MCP6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

230844:Nrg3
gene id: 230844:Nrg3
uniprot id: A0A6I9M1V5
names: Caution
names: Similarity
messages: Belongs to the neuregulin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

230844:Mphosph10
gene id: 230844:Mphosph10
uniprot id: A0A6I9LAR1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MPP10 family.
messages: Component of the 60-80S U3 small nucleolar ribonucleoprotein (U3 snoRNP). Required for the early cleavages during pre-18S ribosomal RNA processing.
messages: nucleolus

230844:Mknk2
gene id: 230844:Mknk2
uniprot id: A0A6I9L6R2
uniprot id: A0A6J0DBD4
uniprot id: A0A6J0DBP4
names: Similarity
messages: Belongs to the protein kinase superfamily.

230844:Suclg1
gene id: 230844:Suclg1
uniprot id: A0A6I9M2R5
uniprot id: A0A6J0E594
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterodimer of an alpha and a beta subunit. Different beta subunits determine nucleotide specificity. Together with the ATP-specific beta subunit SUCLA2, forms an ADP-forming succinyl-CoA synthetase (A-SCS). Together with the GTP-specific beta subunit SUCLG2 forms a GDP-forming succinyl-CoA synthetase (G-SCS).
messages: Mitochondrion
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and specificity for either ATP or GTP is provided by different beta subunits.

230844:Piwil1
gene id: 230844:Piwil1
uniprot id: A0A6I9KUM6
names: Similarity
messages: Belongs to the argonaute family.

230844:Vkorc1
gene id: 230844:Vkorc1
uniprot id: A0A6I9L5R8
uniprot id: A0A6I9LD88
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VKOR family.
messages: Endoplasmic reticulum membrane
messages: Membrane

230844:Chmp4b
gene id: 230844:Chmp4b
uniprot id: A0A6I9M9T6
names: Similarity
messages: Belongs to the SNF7 family.

230844:Fzr1
gene id: 230844:Fzr1
uniprot id: A0A6J0DBC0
names: Similarity
messages: Belongs to the WD repeat CDC20/Fizzy family.

230844:LOC102925191
gene id: 230844:LOC102925191
uniprot id: A0A6I9LQJ3
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS4 family.

230844:Rps3
gene id: 230844:Rps3
uniprot id: A0A6I9LPK1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Membrane
messages: Mitochondrion inner membrane
messages: spindle

230844:Stoml2
gene id: 230844:Stoml2
uniprot id: A0A6I9LLD5
names: Similarity
messages: Belongs to the band 7/mec-2 family.

230844:Mex3c
gene id: 230844:Mex3c
uniprot id: A0A6I9KYN9
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

230844:Cast
gene id: 230844:Cast
uniprot id: A0A6I9L8Z3
uniprot id: A0A6I9LAG4
uniprot id: A0A6I9LHQ0
uniprot id: A0A6I9LIR7
uniprot id: A0A6I9LM70
uniprot id: A0A6I9LMA6
uniprot id: A0A6J0DEZ2
names: Function
names: Similarity
messages: Belongs to the protease inhibitor I27 (calpastatin) family.
messages: Specific inhibition of calpain (calcium-dependent cysteine protease). Plays a key role in postmortem tenderization of meat and have been proposed to be involved in muscle protein degradation in living tissue.

230844:Cd320
gene id: 230844:Cd320
uniprot id: A0A6I9M760
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

230844:Stk38
gene id: 230844:Stk38
uniprot id: A0A6J0DW78
names: Similarity
messages: Belongs to the protein kinase superfamily.

230844:Pdzk1ip1
gene id: 230844:Pdzk1ip1
uniprot id: A0A6J0E1N7
names: Subcellular Location Annotation
messages: Membrane

230844:Krt7
gene id: 230844:Krt7
uniprot id: A0A6I9LDU0
names: Similarity
messages: Belongs to the intermediate filament family.

230844:Irx5
gene id: 230844:Irx5
uniprot id: A0A6I9LT26
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TALE/IRO homeobox family.
messages: Nucleus

230844:Zwilch
gene id: 230844:Zwilch
uniprot id: A0A6I9L183
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ZWILCH family.
messages: Component of the RZZ complex.
messages: Essential component of the mitotic checkpoint, which prevents cells from prematurely exiting mitosis. Required for the assembly of the dynein-dynactin and MAD1-MAD2 complexes onto kinetochores. Its function related to the spindle assembly machinery is proposed to depend on its association in the mitotic RZZ complex.
messages: kinetochore

230844:Cenpa
gene id: 230844:Cenpa
uniprot id: A0A6I9MF94
names: Similarity
messages: Belongs to the histone H3 family.

230844:Nkx6-2
gene id: 230844:Nkx6-2
uniprot id: A0A6I9LP57
names: Subcellular Location Annotation
messages: Nucleus

230844:Gpr162
gene id: 230844:Gpr162
uniprot id: A0A6I9M9R2
names: Subcellular Location Annotation
messages: Membrane

230844:Pomk
gene id: 230844:Pomk
uniprot id: A0A6I9LPU5
uniprot id: A0A6J0DPS0
names: Function
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Protein O-mannose kinase that specifically mediates phosphorylation at the 6-position of an O-mannose of the trisaccharide (N-acetylgalactosamine (GalNAc)-beta-1,3-N-acetylglucosamine (GlcNAc)-beta-1,4-mannose) to generate phosphorylated O-mannosyl trisaccharide (N-acetylgalactosamine-beta-1,3-N-acetylglucosamine-beta-1,4-(phosphate-6-)mannose). Phosphorylated O-mannosyl trisaccharide is a carbohydrate structure present in alpha-dystroglycan (DAG1), which is required for binding laminin G-like domain-containing extracellular proteins with high affinity. Only shows kinase activity when the GalNAc-beta-3-GlcNAc-beta-terminus is linked to the 4-position of O-mannose, suggesting that this disaccharide serves as the substrate recognition motif.

230844:LOC102916168
gene id: 230844:LOC102916168
uniprot id: A0A6I9MK43
names: Similarity
messages: Belongs to the SPATA31 family.

230844:Mdk
gene id: 230844:Mdk
uniprot id: A0A6J0DU69
names: Similarity
messages: Belongs to the pleiotrophin family.

230844:Ptprb
gene id: 230844:Ptprb
uniprot id: A0A6I9LVU3
uniprot id: A0A6J0E590
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Receptor class 3 subfamily.

230844:LOC102927301
gene id: 230844:LOC102927301
uniprot id: A0A6I9M6T6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Cnot6l
gene id: 230844:Cnot6l
uniprot id: A0A6I9M6M1
uniprot id: A0A6J0CSR8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CCR4/nocturin family.
messages: Cytoplasm
messages: Nucleus

230844:Tekt4
gene id: 230844:Tekt4
uniprot id: A0A6I9LKW6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tektin family.
messages: Microtubule inner protein (MIP) part of the dynein-decorated doublet microtubules (DMTs) in cilia and flagellar axoneme. Forms filamentous polymers in the walls of ciliary and flagellar microtubules. Required for normal sperm mobility.
messages: flagellum

230844:Dbndd1
gene id: 230844:Dbndd1
uniprot id: A0A6I9LZD2
names: Similarity
messages: Belongs to the dysbindin family.

230844:Ang
gene id: 230844:Ang
uniprot id: A0A6I9M9K1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the pancreatic ribonuclease family.
messages: Endonuclease that catalyzes the cleavage of RNA on the 3' side of pyrimidine nucleotides. Acts on single-stranded and double-stranded RNA.
messages: Monomer. Interacts with and forms tight 1:1 complexes with RNH1. Dimerization of two such complexes may occur. Interaction with RNH1 inhibits this protein.

230844:LOC102912232
gene id: 230844:LOC102912232
uniprot id: A0A6I9MLK6
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

230844:Gpr182
gene id: 230844:Gpr182
uniprot id: A0A6I9MKD9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Map3k6
gene id: 230844:Map3k6
uniprot id: A0A6I9LDW7
names: Similarity
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.

230844:LOC102915783
gene id: 230844:LOC102915783
uniprot id: A0A6I9LCH6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:LOC102925295
gene id: 230844:LOC102925295
uniprot id: A0A6J0E6K9
names: Similarity
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.

230844:Sema4b
gene id: 230844:Sema4b
uniprot id: A0A6J0CYY9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

230844:LOC102906265
gene id: 230844:LOC102906265
uniprot id: A0A6I9MBU2
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

230844:Ppp1r16b
gene id: 230844:Ppp1r16b
uniprot id: A0A6I9KUI6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

230844:Nkain4
gene id: 230844:Nkain4
uniprot id: A0A6I9L330
uniprot id: A0A6I9LB81
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NKAIN family.
messages: Cell membrane
messages: Membrane

230844:Vps28
gene id: 230844:Vps28
uniprot id: A0A6I9M2X0
names: Function
names: Similarity
messages: Belongs to the VPS28 family.
messages: Component of the ESCRT-I complex (endosomal sorting complex required for transport I), a regulator of vesicular trafficking process.

230844:Slc7a9
gene id: 230844:Slc7a9
uniprot id: A0A6J0DVS9
names: Subcellular Location Annotation
messages: Membrane

230844:Hspa14
gene id: 230844:Hspa14
uniprot id: A0A6I9LL91
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the heat shock protein 70 family.
messages: Component of ribosome-associated complex (RAC), a heterodimer composed of Hsp70/DnaK-type chaperone HSPA14 and Hsp40/DnaJ-type chaperone DNAJC2.
messages: Component of the ribosome-associated complex (RAC), a complex involved in folding or maintaining nascent polypeptides in a folding-competent state. In the RAC complex, binds to the nascent polypeptide chain, while DNAJC2 stimulates its ATPase activity.
messages: cytosol

230844:Mchr1
gene id: 230844:Mchr1
uniprot id: A0A6I9LLU6
names: Subcellular Location Annotation
names: Subunit
messages: Cell membrane
messages: Interacts with NCDN.
messages: Membrane

230844:Ube2i
gene id: 230844:Ube2i
uniprot id: A0A6I9LGJ4
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

230844:LOC102926572
gene id: 230844:LOC102926572
uniprot id: A0A6I9MDC0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Smdt1
gene id: 230844:Smdt1
uniprot id: A0A6I9LKF6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMDT1/EMRE family.
messages: Component of the uniplex complex. Interacts (via the transmembrane region) with MCU (via the first transmembrane region); the interaction is direct.
messages: Essential regulatory subunit of the mitochondrial calcium uniporter complex (uniplex), a complex that mediates calcium uptake into mitochondria.
messages: Membrane
messages: Mitochondrion inner membrane

230844:LOC102922909
gene id: 230844:LOC102922909
uniprot id: A0A6J0DXT1
names: Similarity
messages: Belongs to the protein kinase superfamily.

230844:Fads2
gene id: 230844:Fads2
uniprot id: A0A6I9MEG9
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane

230844:Cryba1
gene id: 230844:Cryba1
uniprot id: A0A6I9L5F0
names: Similarity
messages: Belongs to the beta/gamma-crystallin family.

230844:Slc5a11
gene id: 230844:Slc5a11
uniprot id: A0A6I9LJS7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Cell membrane
messages: Membrane

230844:Fam83g
gene id: 230844:Fam83g
uniprot id: A0A6I9KYX0
names: Similarity
messages: Belongs to the FAM83 family.

230844:Ckmt2
gene id: 230844:Ckmt2
uniprot id: A0A6I9LKY2
names: Similarity
messages: Belongs to the ATP:guanido phosphotransferase family.

230844:B4gat1
gene id: 230844:B4gat1
uniprot id: A0A6I9LB93
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 49 family.
messages: Golgi apparatus membrane
messages: Membrane

230844:Slc44a4
gene id: 230844:Slc44a4
uniprot id: A0A6I9M3M0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CTL (choline transporter-like) family.
messages: Cell membrane
messages: Choline transporter.
messages: Membrane

230844:LOC102921539
gene id: 230844:LOC102921539
uniprot id: A0A6J0DCP9
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL42 family.

230844:Tspan7
gene id: 230844:Tspan7
uniprot id: A0A6I9LGT3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

230844:LOC102920950
gene id: 230844:LOC102920950
uniprot id: A0A6I9LHH1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UDP-glycosyltransferase family.
messages: Membrane

230844:Tnks
gene id: 230844:Tnks
uniprot id: A0A6I9KZL3
names: Similarity
messages: Belongs to the ARTD/PARP family.

230844:Egf
gene id: 230844:Egf
uniprot id: A0A6J0D1I3
names: Caution
names: Function
names: Subunit
messages: EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6.
messages: Interacts with EGFR and promotes EGFR dimerization.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

230844:Tk1
gene id: 230844:Tk1
uniprot id: A0A6I9M4N9
names: Similarity
messages: Belongs to the thymidine kinase family.

230844:Tafa2
gene id: 230844:Tafa2
uniprot id: A0A6I9L5H9
uniprot id: A0A6J0CYP5
names: Similarity
messages: Belongs to the TAFA family.

230844:Msi2
gene id: 230844:Msi2
uniprot id: A0A6I9KW58
uniprot id: A0A6J0EAZ4
uniprot id: A0A6J0EB04
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Musashi family.
messages: Cytoplasm

230844:Stk39
gene id: 230844:Stk39
uniprot id: A0A6I9L387
names: Similarity
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.

230844:Wnt3a
gene id: 230844:Wnt3a
uniprot id: A0A6I9M7H3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

230844:Fam210a
gene id: 230844:Fam210a
uniprot id: A0A6J0DJW2
names: Similarity
messages: Belongs to the FAM210 family.

230844:Pde6a
gene id: 230844:Pde6a
uniprot id: A0A6I9LZN9
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

230844:LOC102928985
gene id: 230844:LOC102928985
uniprot id: A0A6J0CZ48
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS17 family.

230844:Pdhx
gene id: 230844:Pdhx
uniprot id: A0A6I9LSB6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Mitochondrion matrix

230844:Hopx
gene id: 230844:Hopx
uniprot id: A0A6I9MEF0
names: Subcellular Location Annotation
messages: Nucleus

230844:Lancl1
gene id: 230844:Lancl1
uniprot id: A0A6I9LCK0
names: Similarity
messages: Belongs to the LanC-like protein family.

230844:Eloc
gene id: 230844:Eloc
uniprot id: A0A6I9L8D4
names: Similarity
messages: Belongs to the SKP1 family.

230844:Tspan17
gene id: 230844:Tspan17
uniprot id: A0A6J0D8V4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

230844:Trpm8
gene id: 230844:Trpm8
uniprot id: A0A6I9LR27
names: Subcellular Location Annotation
messages: Membrane

230844:Nr1i3
gene id: 230844:Nr1i3
uniprot id: A0A6I9M6P2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR1 subfamily.
messages: Nucleus

230844:Slc29a3
gene id: 230844:Slc29a3
uniprot id: A0A6I9KX28
names: Similarity
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Belongs to the SLC29A/ENT transporter (TC 2.A.57) family.
messages: Membrane

230844:Carm1
gene id: 230844:Carm1
uniprot id: A0A6J0E021
names: Subcellular Location Annotation
messages: Nucleus

230844:Ppp3cb
gene id: 230844:Ppp3cb
uniprot id: A0A6I9LJ39
uniprot id: A0A6I9LLF4
uniprot id: A0A6I9LTQ5
uniprot id: A0A6I9LUH6
uniprot id: A0A6I9LYX7
uniprot id: A0A6J0DU19
uniprot id: A0A6J0DVA8
names: Similarity
messages: Belongs to the PPP phosphatase family. PP-2B subfamily.

230844:Fgfr1
gene id: 230844:Fgfr1
uniprot id: A0A6I9LFV0
uniprot id: A0A6I9LHI6
uniprot id: A0A6I9LPW1
uniprot id: A0A6I9LVM5
uniprot id: A0A6J0DPT2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. Fibroblast growth factor receptor subfamily.
messages: Cell membrane
messages: Cytoplasmic vesicle
messages: Membrane
messages: Nucleus
messages: Vesicle
messages: cytosol

230844:Coq3
gene id: 230844:Coq3
uniprot id: A0A6I9LII4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. UbiG/COQ3 family.
messages: Component of a multi-subunit COQ enzyme complex, composed of at least COQ3, COQ4, COQ5, COQ6, COQ7 and COQ9.
messages: Mitochondrion inner membrane
messages: O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway.

230844:Smc2
gene id: 230844:Smc2
uniprot id: A0A6J0CM14
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SMC family. SMC2 subfamily.
messages: Chromosome
messages: Nucleus

230844:Syf2
gene id: 230844:Syf2
uniprot id: A0A6I9LAC4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SYF2 family.
messages: Involved in pre-mRNA splicing.
messages: May be part of a spliceosome complex.
messages: Nucleus

230844:Sf3a1
gene id: 230844:Sf3a1
uniprot id: A0A6I9KXT3
names: Subcellular Location Annotation
messages: Nucleus

230844:Slf2
gene id: 230844:Slf2
uniprot id: A0A6I9M2E3
names: Similarity
messages: Belongs to the FAM178 family.

230844:LOC102917587
gene id: 230844:LOC102917587
uniprot id: A0A6I9MC10
names: Similarity
messages: Belongs to the cytochrome P450 family.

230844:Ovol2
gene id: 230844:Ovol2
uniprot id: A0A6I9LIH4
names: Subcellular Location Annotation
messages: Nucleus

230844:LOC102917658
gene id: 230844:LOC102917658
uniprot id: A0A6I9LJA9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UDP-glycosyltransferase family.
messages: Membrane

230844:C7H11orf54
gene id: 230844:C7H11orf54
uniprot id: A0A6I9LUF1
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Exhibits ester hydrolase activity on the substrate p-nitrophenyl acetate.
messages: Monomer.
messages: Nucleus

230844:Ubac2
gene id: 230844:Ubac2
uniprot id: A0A6I9LKV0
names: Subcellular Location Annotation
messages: Membrane

230844:LOC102928741
gene id: 230844:LOC102928741
uniprot id: A0A6I9LY77
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UQCRH/QCR6 family.
messages: Component of the ubiquinol-cytochrome c oxidoreductase, a multisubunit transmembrane complex that is part of the mitochondrial electron transport chain which drives oxidative phosphorylation.
messages: Mitochondrion inner membrane

230844:Smarca4
gene id: 230844:Smarca4
uniprot id: A0A6J0DMM8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNF2/RAD54 helicase family.
messages: Nucleus

230844:Lrwd1
gene id: 230844:Lrwd1
uniprot id: A0A6I9KUW8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LRWD1 family.
messages: centrosome
messages: kinetochore
messages: telomere

230844:Kcnj8
gene id: 230844:Kcnj8
uniprot id: A0A6I9L4L1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family.
messages: Membrane

230844:Slain1
gene id: 230844:Slain1
uniprot id: A0A6I9L7P4
uniprot id: A0A6J0D988
names: Similarity
messages: Belongs to the SLAIN motif-containing family.

230844:Ccnjl
gene id: 230844:Ccnjl
uniprot id: A0A6I9KV15
names: Similarity
messages: Belongs to the cyclin family.

230844:Foxg1
gene id: 230844:Foxg1
uniprot id: A0A6I9L9I2
names: Function
names: Subcellular Location Annotation
messages: Nucleus
messages: Transcription repression factor which plays an important role in the establishment of the regional subdivision of the developing brain and in the development of the telencephalon.

230844:Osgepl1
gene id: 230844:Osgepl1
uniprot id: A0A6J0D254
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 divalent metal cation per subunit.
messages: Mitochondrion
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in mitochondrial tRNAs that read codons beginning with adenine. Probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. Involved in mitochondrial genome maintenance.

230844:Prdm15
gene id: 230844:Prdm15
uniprot id: A0A6I9MKY0
names: Subcellular Location Annotation
messages: Nucleus

230844:Gmfg
gene id: 230844:Gmfg
uniprot id: A0A6I9LXH2
uniprot id: A0A6J0DZP7
uniprot id: A0A6J0E4Q6
names: Similarity
messages: Belongs to the actin-binding proteins ADF family. GMF subfamily.

230844:Serpinb5
gene id: 230844:Serpinb5
uniprot id: A0A6I9MBC9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the serpin family. Ov-serpin subfamily.
messages: extracellular space

230844:Usp7
gene id: 230844:Usp7
uniprot id: A0A6I9M3A8
uniprot id: A0A6J0CG04
names: Similarity
messages: Belongs to the peptidase C19 family.

230844:Phospho2
gene id: 230844:Phospho2
uniprot id: A0A6I9KWT0
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. PHOSPHO family.

230844:LOC102907917
gene id: 230844:LOC102907917
uniprot id: A0A6I9MJE4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:LOC102916854
gene id: 230844:LOC102916854
uniprot id: A0A6J0DW61
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CRF-binding protein family.
messages: Binds CRF and inactivates it. May prevent inappropriate pituitary-adrenal stimulation in pregnancy.
messages: Secreted

230844:LOC107402138
gene id: 230844:LOC107402138
uniprot id: A0A6J0DTQ0
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LDLR family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

230844:LOC102916473
gene id: 230844:LOC102916473
uniprot id: A0A6I9LAR3
names: Similarity
messages: Belongs to the cytochrome b5 family.

230844:Tfap2e
gene id: 230844:Tfap2e
uniprot id: A0A6I9M5L6
names: Similarity
messages: Belongs to the AP-2 family.

230844:Tspan4
gene id: 230844:Tspan4
uniprot id: A0A6I9L666
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

230844:Pdgfc
gene id: 230844:Pdgfc
uniprot id: A0A6J0E1V7
names: Caution
names: Similarity
messages: Belongs to the PDGF/VEGF growth factor family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

230844:Timp1
gene id: 230844:Timp1
uniprot id: A0A6I9MC71
names: Similarity
messages: Belongs to the protease inhibitor I35 (TIMP) family.

230844:Vcam1
gene id: 230844:Vcam1
uniprot id: A0A6I9LF49
names: Subcellular Location Annotation
messages: Cell membrane

230844:Tm4sf20
gene id: 230844:Tm4sf20
uniprot id: A0A6I9LU20
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L6 tetraspanin family.
messages: Membrane

230844:LOC102928677
gene id: 230844:LOC102928677
uniprot id: A0A6I9MA26
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Cth
gene id: 230844:Cth
uniprot id: A0A6I9L8T2
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

230844:Krt13
gene id: 230844:Krt13
uniprot id: A0A6I9M9W1
names: Similarity
messages: Belongs to the intermediate filament family.

230844:Slc6a9
gene id: 230844:Slc6a9
uniprot id: A0A6J0CRQ7
uniprot id: A0A6J0CT88
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. SLC6A9 subfamily.
messages: Cell membrane
messages: Membrane

230844:Rpl15
gene id: 230844:Rpl15
uniprot id: A0A6I9L1D4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic ribosomal protein eL15 family.
messages: Cytoplasm

230844:Katnb1
gene id: 230844:Katnb1
uniprot id: A0A6J0E1R9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the WD repeat KATNB1 family.
messages: Cytoplasm
messages: Interacts with KATNA1. This interaction enhances the microtubule binding and severing activity of KATNA1 and also targets this activity to the centrosome. This interaction is weakly competed by KATNBL1 which has a lower affinity for it. Interacts with ASPM; the katanin complex formation KATNA1:KATNB1 is required for the association of ASPM. Interacts with dynein, microtubules, NDEL1 and PAFAH1B1. Interacts with KATNAL1; this interaction is weakly competed by KATNBL1 which has a lower affinity for it. Interacts with CAMSAP2 and CAMSAP3; leading to regulate the length of CAMSAP-decorated microtubule stretches.
messages: Participates in a complex which severs microtubules in an ATP-dependent manner. May act to target the enzymatic subunit of this complex to sites of action such as the centrosome. Microtubule severing may promote rapid reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation. Microtubule release from the mitotic spindle poles may allow depolymerization of the microtubule end proximal to the spindle pole, leading to poleward microtubule flux and poleward motion of chromosome. Microtubule release within the cell body of neurons may be required for their transport into neuronal processes by microtubule-dependent motor proteins. This transport is required for axonal growth.
messages: centrosome
messages: cytoskeleton
messages: spindle
messages: spindle pole

230844:Zkscan2
gene id: 230844:Zkscan2
uniprot id: A0A6J0DN02
names: Function
names: Subcellular Location Annotation
messages: May be involved in transcriptional regulation.
messages: Nucleus

230844:Gjc1
gene id: 230844:Gjc1
uniprot id: A0A6J0D5F1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins. Interacts with CNST.
messages: Belongs to the connexin family. Gamma-type subfamily.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

230844:Cdk8
gene id: 230844:Cdk8
uniprot id: A0A6I9LB16
uniprot id: A0A6I9LJD1
uniprot id: A0A6J0DDM0
uniprot id: A0A6J0DFG5
uniprot id: A0A6J0DG29
names: Similarity
messages: Belongs to the protein kinase superfamily.

230844:Cd74
gene id: 230844:Cd74
uniprot id: A0A6I9LZM3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

230844:Enoph1
gene id: 230844:Enoph1
uniprot id: A0A6I9L1U4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HAD-like hydrolase superfamily. MasA/MtnC family.
messages: Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene).
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Nucleus

230844:Cnmd
gene id: 230844:Cnmd
uniprot id: A0A6I9LSK0
uniprot id: A0A6I9M8U2
names: Similarity
messages: Belongs to the chondromodulin-1 family.

230844:LOC102907099
gene id: 230844:LOC102907099
uniprot id: A0A6I9L9X4
uniprot id: A0A6J0D4I9
names: Similarity
messages: Belongs to the DDI1 family.

230844:Chn2
gene id: 230844:Chn2
uniprot id: A0A6I9M3J6
names: Function
messages: GTPase-activating protein for p21-rac.

230844:Inhbb
gene id: 230844:Inhbb
uniprot id: A0A6I9MD34
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TGF-beta family.
messages: Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition. Inhibins appear to oppose the functions of activins.
messages: Secreted

230844:Chmp2a
gene id: 230844:Chmp2a
uniprot id: A0A6J0CWG4
names: Similarity
messages: Belongs to the SNF7 family.

230844:LOC102908963
gene id: 230844:LOC102908963
uniprot id: A0A6I9LGY0
names: Similarity
messages: Belongs to the calcitonin family.

230844:Hif1a
gene id: 230844:Hif1a
uniprot id: A0A6I9M4W2
uniprot id: A0A6I9MBU3
uniprot id: A0A6J0CEY4
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus speckle

230844:Glyr1
gene id: 230844:Glyr1
uniprot id: A0A6I9LIV4
uniprot id: A0A6I9LU87
uniprot id: A0A6J0DS02
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HIBADH-related family. NP60 subfamily.
messages: Chromosome

230844:LOC102918560
gene id: 230844:LOC102918560
uniprot id: A0A6J0CV72
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

230844:Grpel1
gene id: 230844:Grpel1
uniprot id: A0A6I9M100
uniprot id: A0A6J0DX66
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GrpE family.
messages: Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner.
messages: Mitochondrion matrix

230844:Sf3b3
gene id: 230844:Sf3b3
uniprot id: A0A6I9KZT6
names: Subcellular Location Annotation
messages: Nucleus

230844:Dgka
gene id: 230844:Dgka
uniprot id: A0A6I9LS13
uniprot id: A0A6J0E7D2
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic diacylglycerol kinase family.
messages: Monomer.

230844:Rtn2
gene id: 230844:Rtn2
uniprot id: A0A6J0CHM3
uniprot id: A0A6J0CJM5
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

230844:Marveld1
gene id: 230844:Marveld1
uniprot id: A0A6I9LZH7
names: Subcellular Location Annotation
messages: Membrane

230844:LOC102927635
gene id: 230844:LOC102927635
uniprot id: A0A6I9LD33
names: Subcellular Location Annotation
messages: Nucleus

230844:Nfu1
gene id: 230844:Nfu1
uniprot id: A0A6I9LKY3
names: Similarity
messages: Belongs to the NifU family.

230844:Acsl6
gene id: 230844:Acsl6
uniprot id: A0A6I9LJ80
uniprot id: A0A6I9LUM4
uniprot id: A0A6J0DVF8
uniprot id: A0A6J0E0Y6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP-dependent AMP-binding enzyme family.
messages: Catalyzes the conversion of long-chain fatty acids to their active form acyl-CoAs for both synthesis of cellular lipids, and degradation via beta-oxidation.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Mitochondrion outer membrane

230844:Ptch2
gene id: 230844:Ptch2
uniprot id: A0A6I9MB01
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the patched family.
messages: Membrane

230844:LOC102926493
gene id: 230844:LOC102926493
uniprot id: A0A6J0CS49
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:LOC102920409
gene id: 230844:LOC102920409
uniprot id: A0A6I9MEE5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:LOC102921987
gene id: 230844:LOC102921987
uniprot id: A0A6I9M512
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Ppm1f
gene id: 230844:Ppm1f
uniprot id: A0A6I9MA71
names: Similarity
messages: Belongs to the PP2C family.

230844:LOC102924717
gene id: 230844:LOC102924717
uniprot id: A0A6I9L8F7
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL39 family.

230844:Nfe2l1
gene id: 230844:Nfe2l1
uniprot id: A0A6I9L5N3
uniprot id: A0A6J0E496
uniprot id: A0A6J0E5Z8
names: Similarity
messages: Belongs to the bZIP family. CNC subfamily.

230844:Spata18
gene id: 230844:Spata18
uniprot id: A0A6I9LJG7
uniprot id: A0A6J0DFR5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIEAP family.
messages: Cytoplasm
messages: Membrane
messages: Mitochondrion outer membrane

230844:Tmem256
gene id: 230844:Tmem256
uniprot id: A0A6I9L919
uniprot id: A0A6J0CZG9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM256 family.
messages: Membrane

230844:Ccl20
gene id: 230844:Ccl20
uniprot id: A0A6I9LZ55
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the intercrine beta (chemokine CC) family.
messages: Secreted

230844:Eml3
gene id: 230844:Eml3
uniprot id: A0A6I9MJG6
names: Similarity
messages: Belongs to the WD repeat EMAP family.

230844:Lin9
gene id: 230844:Lin9
uniprot id: A0A6I9KZY6
uniprot id: A0A6J0CZW9
names: Similarity
messages: Belongs to the lin-9 family.

230844:Tomt
gene id: 230844:Tomt
uniprot id: A0A6J0CG93
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-dependent O-methyltransferase family.

230844:Oxr1
gene id: 230844:Oxr1
uniprot id: A0A6J0DBA8
uniprot id: A0A6J0DCW1
uniprot id: A0A6J0DD27
names: Similarity
messages: Belongs to the OXR1 family.

230844:Abhd1
gene id: 230844:Abhd1
uniprot id: A0A6I9MK72
names: Similarity
messages: Belongs to the AB hydrolase superfamily. AB hydrolase 4 family.

230844:LOC102917944
gene id: 230844:LOC102917944
uniprot id: A0A6I9MJN1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Cercam
gene id: 230844:Cercam
uniprot id: A0A6I9LQV9
names: Similarity
messages: Belongs to the glycosyltransferase 25 family.

230844:Rbm46
gene id: 230844:Rbm46
uniprot id: A0A6I9LK11
uniprot id: A0A6I9LVF0
names: Subcellular Location Annotation
messages: Cytoplasm

230844:LOC102917914
gene id: 230844:LOC102917914
uniprot id: A0A6I9M0D3
uniprot id: A0A6J0CJ01
uniprot id: A0A6J0CM69
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Ena/VASP family.
messages: Ena/VASP proteins are actin-associated proteins involved in a range of processes dependent on cytoskeleton remodeling and cell polarity such as axon guidance, lamellipodial and filopodial dynamics, platelet activation and cell migration.
messages: cytoskeleton

230844:Apold1
gene id: 230844:Apold1
uniprot id: A0A6I9L4R2
names: Similarity
messages: Belongs to the apolipoprotein L family.

230844:Lhfpl3
gene id: 230844:Lhfpl3
uniprot id: A0A6J0EB76
uniprot id: A0A6J0EEZ0
names: Subcellular Location Annotation
messages: Membrane

230844:Sim1
gene id: 230844:Sim1
uniprot id: A0A6I9LRI7
uniprot id: A0A6J0DS88
names: Subcellular Location Annotation
messages: Nucleus

230844:Mbtps2
gene id: 230844:Mbtps2
uniprot id: A0A6J0CYG5
uniprot id: A0A6J0CZ31
names: Similarity
messages: Belongs to the peptidase M50A family.

230844:LOC102914251
gene id: 230844:LOC102914251
uniprot id: A0A6I9LYX1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Ociad1
gene id: 230844:Ociad1
uniprot id: A0A6J0DDR5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OCIAD1 family.
messages: Endosome
messages: Interacts with STAT3.
messages: Maintains stem cell potency. Increases STAT3 phosphorylation and controls ERK phosphorylation. May act as a scaffold, increasing STAT3 recruitment onto endosomes.
messages: The OCIA domain is necessary and sufficient for endosomal localization.

230844:Hoatz
gene id: 230844:Hoatz
uniprot id: A0A6I9KWN6
names: Similarity
messages: Belongs to the HOATZ family.

230844:Ppp1r1b
gene id: 230844:Ppp1r1b
uniprot id: A0A6J0EAM4
names: Similarity
messages: Belongs to the protein phosphatase inhibitor 1 family.

230844:Naglu
gene id: 230844:Naglu
uniprot id: A0A6I9MF03
names: Subcellular Location Annotation
messages: Lysosome

230844:Rgn
gene id: 230844:Rgn
uniprot id: A0A6I9M1K8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMP-30/CGR1 family.
messages: Cytoplasm
messages: Monomer.

230844:Rpl36
gene id: 230844:Rpl36
uniprot id: A0A6I9LUB9
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL36 family.

230844:Gtf2f1
gene id: 230844:Gtf2f1
uniprot id: A0A6I9LEK1
uniprot id: A0A6I9LUD4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TFIIF alpha subunit family.
messages: Nucleus
messages: TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation.

230844:Cmc4
gene id: 230844:Cmc4
uniprot id: A0A6J0CSU8
names: Similarity
messages: Belongs to the CMC4 family.

230844:Nhs
gene id: 230844:Nhs
uniprot id: A0A6I9L512
uniprot id: A0A6I9L8L3
uniprot id: A0A6J0CXA8
names: Similarity
messages: Belongs to the NHS family.

230844:LOC102923187
gene id: 230844:LOC102923187
uniprot id: A0A6I9LGY4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Klhl22
gene id: 230844:Klhl22
uniprot id: A0A6I9LWQ3
names: Subcellular Location Annotation
messages: Lysosome
messages: Nucleus
messages: centrosome
messages: cytosol
messages: spindle

230844:Ppfibp2
gene id: 230844:Ppfibp2
uniprot id: A0A6I9M2J4
names: Similarity
messages: Belongs to the liprin family. Liprin-beta subfamily.

230844:LOC102928763
gene id: 230844:LOC102928763
uniprot id: A0A6I9L089
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

230844:Ddx24
gene id: 230844:Ddx24
uniprot id: A0A6J0E8H1
names: Domain
names: Function
names: Similarity
messages: Belongs to the DEAD box helicase family.
messages: RNA helicase.
messages: The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.

230844:Prkra
gene id: 230844:Prkra
uniprot id: A0A6I9L707
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRKRA family.
messages: perinuclear region

230844:Fgf4
gene id: 230844:Fgf4
uniprot id: A0A6I9LDY6
names: Similarity
messages: Belongs to the heparin-binding growth factors family.

230844:Tmem45b
gene id: 230844:Tmem45b
uniprot id: A0A6I9MF04
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM45 family.
messages: Membrane

230844:Phactr2
gene id: 230844:Phactr2
uniprot id: A0A6J0DCL6
names: Similarity
names: Subunit
messages: Belongs to the phosphatase and actin regulator family.
messages: Binds PPP1CA and actin.

230844:Slc17a9
gene id: 230844:Slc17a9
uniprot id: A0A6I9LEW7
names: Subcellular Location Annotation
messages: Membrane

230844:LOC102909980
gene id: 230844:LOC102909980
uniprot id: A0A6I9MAR7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Lef1
gene id: 230844:Lef1
uniprot id: A0A6I9KTE6
uniprot id: A0A6I9L1Z5
uniprot id: A0A6J0CYT1
uniprot id: A0A6J0CYU5
uniprot id: A0A6J0D172
uniprot id: A0A6J0D4C7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TCF/LEF family.
messages: Nucleus

230844:Nrde2
gene id: 230844:Nrde2
uniprot id: A0A6I9M982
uniprot id: A0A6J0EEQ1
names: Similarity
messages: Belongs to the NRDE2 family.

230844:Nol10
gene id: 230844:Nol10
uniprot id: A0A6I9LCA1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat NOL10/ENP2 family.
messages: nucleolus

230844:Sdhd
gene id: 230844:Sdhd
uniprot id: A0A6I9L6Q3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CybS family.
messages: Component of complex II composed of four subunits: the flavoprotein (FP) SDHA, iron-sulfur protein (IP) SDHB, and a cytochrome b560 composed of SDHC and SDHD.
messages: Membrane
messages: Membrane-anchoring subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).
messages: Mitochondrion inner membrane

230844:Pmp2
gene id: 230844:Pmp2
uniprot id: A0A6I9L7I6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.
messages: May play a role in lipid transport protein in Schwann cells. May bind cholesterol.
messages: Monomer.

230844:Ampd3
gene id: 230844:Ampd3
uniprot id: A0A6I9LKH8
uniprot id: A0A6J0DAZ9
uniprot id: A0A6J0DD98
uniprot id: A0A6J0DI03
names: Similarity
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.
messages: Homotetramer.

230844:LOC102915025
gene id: 230844:LOC102915025
uniprot id: A0A6I9LBH7
names: Similarity
messages: Belongs to the N-acetylmuramoyl-L-alanine amidase 2 family.

230844:LOC102921327
gene id: 230844:LOC102921327
uniprot id: A0A6J0CVR7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:LOC102905406
gene id: 230844:LOC102905406
uniprot id: A0A6I9LXR3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Ppp3r1
gene id: 230844:Ppp3r1
uniprot id: A0A6I9M924
names: Similarity
messages: Belongs to the calcineurin regulatory subunit family.

230844:Pms2
gene id: 230844:Pms2
uniprot id: A0A6I9LPB0
uniprot id: A0A6J0DPG7
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.

230844:Tulp4
gene id: 230844:Tulp4
uniprot id: A0A6I9L6J3
names: Similarity
messages: Belongs to the TUB family.

230844:LOC102916308
gene id: 230844:LOC102916308
uniprot id: A0A6I9LLQ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone H1/H5 family.
messages: Nucleus

230844:Ehf
gene id: 230844:Ehf
uniprot id: A0A6J0DRW2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

230844:Adgrg3
gene id: 230844:Adgrg3
uniprot id: A0A6I9LVB0
names: Subcellular Location Annotation
messages: Membrane

230844:Dok2
gene id: 230844:Dok2
uniprot id: A0A6I9M808
uniprot id: A0A6J0E5J3
names: Similarity
messages: Belongs to the DOK family. Type A subfamily.

230844:LOC102909579
gene id: 230844:LOC102909579
uniprot id: A0A6J0CRT3
names: Similarity
messages: Belongs to the TCAF family.

230844:LOC102926577
gene id: 230844:LOC102926577
uniprot id: A0A6I9M822
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

230844:Pear1
gene id: 230844:Pear1
uniprot id: A0A6J0D5I9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

230844:Coq10b
gene id: 230844:Coq10b
uniprot id: A0A6I9L1F8
uniprot id: A0A6I9L8P6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the COQ10 family.
messages: Interacts with coenzyme Q.
messages: Required for the function of coenzyme Q in the respiratory chain. May serve as a chaperone or may be involved in the transport of Q6 from its site of synthesis to the catalytic sites of the respiratory complexes.

230844:LOC102905396
gene id: 230844:LOC102905396
uniprot id: A0A6I9LQR8
names: Similarity
messages: Belongs to the type-B carboxylesterase/lipase family.

230844:Sv2c
gene id: 230844:Sv2c
uniprot id: A0A6I9LWB5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily.
messages: Membrane
messages: synaptic vesicle membrane

230844:Hddc2
gene id: 230844:Hddc2
uniprot id: A0A6J0DK17
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HDDC2 family.
messages: Catalyzes the dephosphorylation of the nucleoside 5'-monophosphates deoxyadenosine monophosphate (dAMP), deoxycytidine monophosphate (dCMP), deoxyguanosine monophosphate (dGMP) and deoxythymidine monophosphate (dTMP).
messages: Homodimer.

230844:Cntf
gene id: 230844:Cntf
uniprot id: A0A6I9M8A2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CNTF family.
messages: CNTF is a survival factor for various neuronal cell types. Seems to prevent the degeneration of motor axons after axotomy.
messages: Cytoplasm

230844:Pik3r1
gene id: 230844:Pik3r1
uniprot id: A0A6I9LH28
uniprot id: A0A6I9LPE7
uniprot id: A0A6J0DNR6
names: Similarity
messages: Belongs to the PI3K p85 subunit family.

230844:Kit
gene id: 230844:Kit
uniprot id: A0A6I9LB68
uniprot id: A0A6I9LJI2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.
messages: Cell membrane
messages: Membrane

230844:Clcn2
gene id: 230844:Clcn2
uniprot id: A0A6I9LPH8
uniprot id: A0A6J0E0G7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chloride channel (TC 2.A.49) family. ClC-2/CLCN2 subfamily.
messages: Cell membrane
messages: Membrane

230844:LOC102911930
gene id: 230844:LOC102911930
uniprot id: A0A6I9LNF8
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

230844:LOC102912543
gene id: 230844:LOC102912543
uniprot id: A0A6I9LF99
names: Similarity
messages: Belongs to the cornifin (SPRR) family.

230844:LOC102912110
gene id: 230844:LOC102912110
uniprot id: A0A6J0CRR9
names: Similarity
messages: Belongs to the Arg-specific ADP-ribosyltransferase family.

230844:LOC102905769
gene id: 230844:LOC102905769
uniprot id: A0A6I9MBL3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Zdhhc23
gene id: 230844:Zdhhc23
uniprot id: A0A6I9LAK3
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

230844:Mmachc
gene id: 230844:Mmachc
uniprot id: A0A6I9LQC9
names: Similarity
messages: Belongs to the MMACHC family.

230844:Ca1
gene id: 230844:Ca1
uniprot id: A0A6I9M9D6
names: Function
names: Similarity
messages: Belongs to the alpha-carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

230844:LOC102907097
gene id: 230844:LOC102907097
uniprot id: A0A6I9L2F9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptobrevin family.
messages: Membrane

230844:LOC102923042
gene id: 230844:LOC102923042
uniprot id: A0A6I9L028
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 2-5A synthase family.
messages: Cytoplasm

230844:LOC102903612
gene id: 230844:LOC102903612
uniprot id: A0A6I9LR50
uniprot id: A0A6J0DIT4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:LOC102920611
gene id: 230844:LOC102920611
uniprot id: A0A6J0CS44
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MTFR1 family.
messages: Mitochondrion
messages: Plays a role in mitochondrial aerobic respiration. Regulates mitochondrial organization and fission.

230844:LOC102912408
gene id: 230844:LOC102912408
uniprot id: A0A6I9MBS6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Kcna5
gene id: 230844:Kcna5
uniprot id: A0A6J0E2L8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the potassium channel family. A (Shaker) (TC 1.A.1.2) subfamily. Kv1.5/KCNA5 sub-subfamily.
messages: Cell membrane
messages: Membrane

230844:Chrna5
gene id: 230844:Chrna5
uniprot id: A0A6J0DY34
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

230844:Asb11
gene id: 230844:Asb11
uniprot id: A0A6I9KY94
uniprot id: A0A6I9L593
names: Similarity
messages: Belongs to the ankyrin SOCS box (ASB) family.

230844:LOC102916892
gene id: 230844:LOC102916892
uniprot id: A0A6J0CRQ2
uniprot id: A0A6J0CT79
uniprot id: A0A6J0CW92
names: Function
names: Subcellular Location Annotation
messages: Prosaposin: Behaves as a myelinotrophic and neurotrophic factor, these effects are mediated by its G-protein-coupled receptors, GPR37 and GPR37L1, undergoing ligand-mediated internalization followed by ERK phosphorylation signaling.
messages: Saposins are specific low-molecular mass non-enzymic proteins, they participate in the lysosomal degradation of sphingolipids, which takes place by the sequential action of specific hydrolases.
messages: Secreted

230844:Dusp4
gene id: 230844:Dusp4
uniprot id: A0A6I9L6V7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.
messages: Nucleus

230844:LOC121820817
gene id: 230844:LOC121820817
uniprot id: A0A6I9LTA6
names: Similarity
messages: Belongs to the aldo/keto reductase family.

230844:Des
gene id: 230844:Des
uniprot id: A0A6I9L315
names: Similarity
messages: Belongs to the intermediate filament family.

230844:Sdhb
gene id: 230844:Sdhb
uniprot id: A0A6I9L9Y6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Binds 1 [3Fe-4S] cluster.
messages: Binds 1 [4Fe-4S] cluster.
messages: Iron-sulfur protein (IP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).
messages: Iron-sulfur protein (IP) subunit of the succinate dehydrogenase complex (mitochondrial respiratory chain complex II), responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).
messages: Mitochondrion inner membrane

230844:Gadd45a
gene id: 230844:Gadd45a
uniprot id: A0A6I9LRF0
names: Similarity
messages: Belongs to the GADD45 family.

230844:Tmem230
gene id: 230844:Tmem230
uniprot id: A0A6I9LJP1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM134/TMEM230 family.
messages: Early endosome
messages: Endosome
messages: Involved in trafficking and recycling of synaptic vesicles.
messages: Late endosome
messages: Membrane
messages: Recycling endosome
messages: autophagosome
messages: synaptic vesicle
messages: trans-Golgi network

230844:Abhd3
gene id: 230844:Abhd3
uniprot id: A0A6J0E4P2
names: Similarity
messages: Belongs to the AB hydrolase superfamily. AB hydrolase 4 family.

230844:Ms4a15
gene id: 230844:Ms4a15
uniprot id: A0A6J0CMB7
names: Similarity
messages: Belongs to the MS4A family.

230844:Tfap2c
gene id: 230844:Tfap2c
uniprot id: A0A6I9LUY5
names: Similarity
messages: Belongs to the AP-2 family.

230844:Fxyd5
gene id: 230844:Fxyd5
uniprot id: A0A6J0DM39
names: Similarity
messages: Belongs to the FXYD family.

230844:Pes1
gene id: 230844:Pes1
uniprot id: A0A6I9L4E8
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pescadillo family.
messages: Chromosome
messages: Component of the PeBoW complex, composed of BOP1, PES1 and WDR12. Within the PeBoW complex BOP1 interacts directly with PES1 and WDR12. The PeBoW complex also associates with the 66S pre-ribosome. Interacts with IRS1 and UBTF. May interact with MAP1B.
messages: Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome.
messages: Sumoylated.
messages: nucleolus
messages: nucleoplasm

230844:Prdm10
gene id: 230844:Prdm10
uniprot id: A0A6J0D5Y2
uniprot id: A0A6J0D741
uniprot id: A0A6J0D7M2
uniprot id: A0A6J0DC69
names: Function
names: Subcellular Location Annotation
messages: May be involved in transcriptional regulation.
messages: Nucleus

230844:Bpifb6
gene id: 230844:Bpifb6
uniprot id: A0A6I9MM49
names: Subcellular Location Annotation
messages: Secreted

230844:Necap1
gene id: 230844:Necap1
uniprot id: A0A6I9M4W7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NECAP family.
messages: Involved in endocytosis.
messages: clathrin-coated vesicle membrane

230844:Galm
gene id: 230844:Galm
uniprot id: A0A6I9M130
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aldose epimerase family.
messages: Monomer.
messages: Mutarotase that catalyzes the interconversion of beta-D-galactose and alpha-D-galactose during galactose metabolism.

230844:Dag1
gene id: 230844:Dag1
uniprot id: A0A6J0DBQ2
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane
messages: The dystroglycan complex is involved in a number of processes including laminin and basement membrane assembly, sarcolemmal stability, cell survival, peripheral nerve myelination, nodal structure, cell migration, and epithelial polarization.
messages: Transmembrane protein that plays important roles in connecting the extracellular matrix to the cytoskeleton. Acts as a cell adhesion receptor in both muscle and non-muscle tissues. Receptor for both DMD and UTRN and, through these interactions, scaffolds axin to the cytoskeleton. Also functions in cell adhesion-mediated signaling and implicated in cell polarity.
messages: cytoskeleton
messages: extracellular space
messages: nucleoplasm
messages: sarcolemma

230844:Atp2a3
gene id: 230844:Atp2a3
uniprot id: A0A6I9LXJ8
uniprot id: A0A6I9MDN8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIA subfamily.
messages: Catalyzes the hydrolysis of ATP coupled with the transport of calcium.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Sarcoplasmic reticulum membrane

230844:Flcn
gene id: 230844:Flcn
uniprot id: A0A6J0CZB4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the folliculin family.
messages: Lysosome membrane
messages: Membrane
messages: Nucleus
messages: centrosome
messages: cilium
messages: cytosol
messages: spindle

230844:Txlna
gene id: 230844:Txlna
uniprot id: A0A6I9M193
names: Similarity
messages: Belongs to the taxilin family.

230844:Ptpn2
gene id: 230844:Ptpn2
uniprot id: A0A6I9KSY1
uniprot id: A0A6I9KYC9
uniprot id: A0A6I9L197
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class 1 subfamily.

230844:Vrk1
gene id: 230844:Vrk1
uniprot id: A0A6J0E188
names: Similarity
messages: Belongs to the protein kinase superfamily.

230844:Ube2f
gene id: 230844:Ube2f
uniprot id: A0A6I9M1N7
uniprot id: A0A6J0E2R3
uniprot id: A0A6J0E4I3
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

230844:Lbx1
gene id: 230844:Lbx1
uniprot id: A0A6I9LQA3
names: Subcellular Location Annotation
messages: Nucleus

230844:Ube2e1
gene id: 230844:Ube2e1
uniprot id: A0A6I9L977
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

230844:Ppip5k2
gene id: 230844:Ppip5k2
uniprot id: A0A6I9LNG8
uniprot id: A0A6I9LW71
uniprot id: A0A6J0DUS9
uniprot id: A0A6J0DUT6
uniprot id: A0A6J0DW37
uniprot id: A0A6J0DW43
uniprot id: A0A6J0DXN5
uniprot id: A0A6J0DXN9
uniprot id: A0A6J0DYJ6
uniprot id: A0A6J0DYK1
uniprot id: A0A6J0E2W8
uniprot id: A0A6J0E2X4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histidine acid phosphatase family. VIP1 subfamily.
messages: Bifunctional inositol kinase that acts in concert with the IP6K kinases to synthesize the diphosphate group-containing inositol pyrophosphates diphosphoinositol pentakisphosphate, PP-InsP5, and bis-diphosphoinositol tetrakisphosphate, (PP)2-InsP4. PP-InsP5 and (PP)2-InsP4, also respectively called InsP7 and InsP8, may regulate a variety of cellular processes, including apoptosis, vesicle trafficking, cytoskeletal dynamics, and exocytosis. Phosphorylates inositol hexakisphosphate (InsP6).
messages: cytosol

230844:Mau2
gene id: 230844:Mau2
uniprot id: A0A6I9MAS2
uniprot id: A0A6I9MEV9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SCC4/mau-2 family.
messages: nucleoplasm

230844:Serpinb11
gene id: 230844:Serpinb11
uniprot id: A0A6I9MBD2
names: Similarity
messages: Belongs to the serpin family.

230844:LOC102928244
gene id: 230844:LOC102928244
uniprot id: A0A6I9LLU3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Prokr1
gene id: 230844:Prokr1
uniprot id: A0A6I9LT67
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

230844:LOC102910253
gene id: 230844:LOC102910253
uniprot id: A0A6I9LDK6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DAN family.
messages: Secreted

230844:Dnah9
gene id: 230844:Dnah9
uniprot id: A0A6I9KYL8
names: Similarity
messages: Belongs to the dynein heavy chain family.

230844:LOC102925680
gene id: 230844:LOC102925680
uniprot id: A0A6I9L899
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Tmem59
gene id: 230844:Tmem59
uniprot id: A0A6I9LEI9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM59 family.
messages: Golgi apparatus membrane
messages: Membrane

230844:Bcl7a
gene id: 230844:Bcl7a
uniprot id: A0A6J0DA46
names: Similarity
messages: Belongs to the BCL7 family.

230844:Izumo2
gene id: 230844:Izumo2
uniprot id: A0A6I9LPS4
names: Similarity
messages: Belongs to the Izumo family.

230844:LOC107401434
gene id: 230844:LOC107401434
uniprot id: A0A6J0DJ83
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phospholipase A2 family.
messages: Binds 1 Ca(2+) ion per subunit.
messages: Secreted

230844:LOC102928691
gene id: 230844:LOC102928691
uniprot id: A0A6I9M6J0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Mrpl51
gene id: 230844:Mrpl51
uniprot id: A0A6I9M899
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mL51 family.
messages: Mitochondrion

230844:Gga2
gene id: 230844:Gga2
uniprot id: A0A6I9LAR0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GGA protein family.
messages: Early endosome membrane
messages: Endosome membrane
messages: Membrane
messages: trans-Golgi network membrane

230844:Ift57
gene id: 230844:Ift57
uniprot id: A0A6I9M457
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IFT57 family.
messages: cilium basal body

230844:Zcchc8
gene id: 230844:Zcchc8
uniprot id: A0A6I9KTA3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZCCHC8 family.
messages: nucleoplasm

230844:Sde2
gene id: 230844:Sde2
uniprot id: A0A6I9LAT8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SDE2 family.
messages: Cytoplasm
messages: Nucleus

230844:LOC102924135
gene id: 230844:LOC102924135
uniprot id: A0A6I9LMF2
names: Similarity
messages: Belongs to the peptidase C1 family.

230844:Htra4
gene id: 230844:Htra4
uniprot id: A0A6I9LVN0
names: Similarity
messages: Belongs to the peptidase S1C family.

230844:Ing2
gene id: 230844:Ing2
uniprot id: A0A6I9KU97
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ING family.
messages: Component of an histone acetyltransferase complex.
messages: Component of an histone acetyltransferase complex. Interacts with H3K4me3 and to a lesser extent with H3K4me2.
messages: Nucleus
messages: The PHD-type zinc finger mediates the binding to H3K4me3.

230844:LOC102925242
gene id: 230844:LOC102925242
uniprot id: A0A6I9MM88
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Tnrc6a
gene id: 230844:Tnrc6a
uniprot id: A0A6I9LAS3
uniprot id: A0A6I9LPQ1
uniprot id: A0A6J0DF29
uniprot id: A0A6J0DMY9
names: Similarity
messages: Belongs to the GW182 family.

230844:Trip11
gene id: 230844:Trip11
uniprot id: A0A6I9M781
uniprot id: A0A6J0EA71
uniprot id: A0A6J0EC84
uniprot id: A0A6J0EEC7
names: Subcellular Location Annotation
messages: Membrane

230844:LOC102923264
gene id: 230844:LOC102923264
uniprot id: A0A6I9L4C6
names: Similarity
messages: Belongs to the TMEM14 family.

230844:LOC102909889
gene id: 230844:LOC102909889
uniprot id: A0A6I9L2T3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alpha/beta interferon family.
messages: Secreted

230844:Ereg
gene id: 230844:Ereg
uniprot id: A0A6J0CIX5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

230844:LOC102908088
gene id: 230844:LOC102908088
uniprot id: A0A6J0CKS1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Prdm13
gene id: 230844:Prdm13
uniprot id: A0A6I9LHH7
names: Subcellular Location Annotation
messages: Nucleus

230844:LOC102915016
gene id: 230844:LOC102915016
uniprot id: A0A6I9M2A8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Mcur1
gene id: 230844:Mcur1
uniprot id: A0A6I9KXD1
uniprot id: A0A6J0CVF9
names: Similarity
messages: Belongs to the CCDC90 family.

230844:Hnmt
gene id: 230844:Hnmt
uniprot id: A0A6J0DQ94
names: Function
names: Subunit
messages: Inactivates histamine by N-methylation. Plays an important role in degrading histamine and in regulating the airway response to histamine.
messages: Monomer.

230844:Glrb
gene id: 230844:Glrb
uniprot id: A0A6I9LMH0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

230844:Mast1
gene id: 230844:Mast1
uniprot id: A0A6I9MK32
uniprot id: A0A6J0CUV0
uniprot id: A0A6J0CVU1
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family.

230844:LOC102925327
gene id: 230844:LOC102925327
uniprot id: A0A6I9MAP6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Ndufs3
gene id: 230844:Ndufs3
uniprot id: A0A6I9LKG7
names: Similarity
messages: Belongs to the complex I 30 kDa subunit family.

230844:LOC102924859
gene id: 230844:LOC102924859
uniprot id: A0A6I9MF34
uniprot id: A0A6I9MIX0
uniprot id: A0A6J0CV09
uniprot id: A0A6J0CXJ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MHC class I family.
messages: Membrane

230844:Susd6
gene id: 230844:Susd6
uniprot id: A0A6J0D1B0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

230844:Supv3l1
gene id: 230844:Supv3l1
uniprot id: A0A6I9L473
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the helicase family.
messages: mitochondrion nucleoid

230844:Phb
gene id: 230844:Phb
uniprot id: A0A6I9KVN7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prohibitin family.
messages: Cell membrane
messages: Membrane
messages: Mitochondrion inner membrane

230844:Chrnb4
gene id: 230844:Chrnb4
uniprot id: A0A6J0DW06
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

230844:E2f3
gene id: 230844:E2f3
uniprot id: A0A6I9KWB6
uniprot id: A0A6I9L307
uniprot id: A0A6J0CH63
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the E2F/DP family.
messages: Nucleus

230844:Fam124b
gene id: 230844:Fam124b
uniprot id: A0A6I9KW05
names: Similarity
messages: Belongs to the FAM124 family.

230844:Akap12
gene id: 230844:Akap12
uniprot id: A0A6I9LFQ1
uniprot id: A0A6J0D9K6
uniprot id: A0A6J0DBF6
uniprot id: A0A6J0DGF0
names: Subcellular Location Annotation
messages: Membrane

230844:Tmem134
gene id: 230844:Tmem134
uniprot id: A0A6I9LCU1
uniprot id: A0A6I9LK64
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM134/TMEM230 family.
messages: Membrane

230844:Itih3
gene id: 230844:Itih3
uniprot id: A0A6I9LSH1
uniprot id: A0A6J0DRV8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ITIH family.
messages: Secreted

230844:Tti2
gene id: 230844:Tti2
uniprot id: A0A6I9LA79
names: Similarity
messages: Belongs to the TTI2 family.

230844:Sycp2
gene id: 230844:Sycp2
uniprot id: A0A6I9L309
uniprot id: A0A6J0D5Q6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SYCP2 family.
messages: Nucleus

230844:Me2
gene id: 230844:Me2
uniprot id: A0A6I9KYE4
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

230844:Sf3b6
gene id: 230844:Sf3b6
uniprot id: A0A6I9LMY4
names: Subcellular Location Annotation
messages: Nucleus

230844:Cdkl4
gene id: 230844:Cdkl4
uniprot id: A0A6J0E759
uniprot id: A0A6J0E9Q8
names: Similarity
messages: Belongs to the protein kinase superfamily.

230844:Pdha1
gene id: 230844:Pdha1
uniprot id: A0A6I9L517
names: Function
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2), and thereby links the glycolytic pathway to the tricarboxylic cycle.

230844:Atxn3
gene id: 230844:Atxn3
uniprot id: A0A6I9LV31
uniprot id: A0A6I9M5X7
uniprot id: A0A6J0E8I1
uniprot id: A0A6J0EA82
uniprot id: A0A6J0EC95
uniprot id: A0A6J0EEE2
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

230844:LOC102906480
gene id: 230844:LOC102906480
uniprot id: A0A6J0CNY1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 2-5A synthase family.
messages: Cytoplasm

230844:Tas2r4
gene id: 230844:Tas2r4
uniprot id: A0A6I9MDX3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor T2R family.
messages: Membrane

230844:Kpna3
gene id: 230844:Kpna3
uniprot id: A0A6I9LTK2
names: Function
names: Similarity
messages: Belongs to the importin alpha family.
messages: Functions in nuclear protein import.

230844:Rsrp1
gene id: 230844:Rsrp1
uniprot id: A0A6I9L304
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RSRP family.
messages: Nucleus
messages: Probably acts as a spliceosomal factor that contributes to spliceosome assembly and regulates the isoform switching of proteins such as PARP6.

230844:Lamc3
gene id: 230844:Lamc3
uniprot id: A0A6J0DX25
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: basement membrane

230844:LOC102919018
gene id: 230844:LOC102919018
uniprot id: A0A6I9M5K8
names: Function
names: Similarity
messages: Belongs to the IPP isomerase type 1 family.
messages: Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP).

230844:Atp13a3
gene id: 230844:Atp13a3
uniprot id: A0A6J0D294
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily.
messages: Membrane

230844:LOC102905077
gene id: 230844:LOC102905077
uniprot id: A0A6I9LYD9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

230844:Arf3
gene id: 230844:Arf3
uniprot id: A0A6I9LBA0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Arf family.
messages: GTP-binding protein involved in protein trafficking; modulates vesicle budding and uncoating within the Golgi apparatus.
messages: Golgi apparatus

230844:Sox11
gene id: 230844:Sox11
uniprot id: A0A6I9LLV9
names: Subcellular Location Annotation
messages: Nucleus

230844:LOC102912539
gene id: 230844:LOC102912539
uniprot id: A0A6J0CNE4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

230844:LOC102926098
gene id: 230844:LOC102926098
uniprot id: A0A6I9MP65
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:LOC102911916
gene id: 230844:LOC102911916
uniprot id: A0A6I9MNV3
names: Subcellular Location Annotation
messages: Membrane

230844:Skap2
gene id: 230844:Skap2
uniprot id: A0A6I9LG35
names: Similarity
messages: Belongs to the SKAP family.

230844:Itih6
gene id: 230844:Itih6
uniprot id: A0A6I9MB04
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ITIH family.
messages: Secreted

230844:Htr1b
gene id: 230844:Htr1b
uniprot id: A0A6J0DGI8
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: G-protein coupled receptor for 5-hydroxytryptamine (serotonin). Also functions as a receptor for various alkaloids and psychoactive substances. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling inhibits adenylate cyclase activity. Arrestin family members inhibit signaling via G proteins and mediate activation of alternative signaling pathways. Regulates the release of 5-hydroxytryptamine, dopamine and acetylcholine in the brain, and thereby affects neural activity, nociceptive processing, pain perception, mood and behavior. Besides, plays a role in vasoconstriction of cerebral arteries.
messages: Homodimer. Heterodimer with HTR1D.
messages: Ligands are bound in a hydrophobic pocket formed by the transmembrane helices.
messages: Membrane
messages: Palmitoylated.
messages: Phosphorylated.

230844:Tssk1b
gene id: 230844:Tssk1b
uniprot id: A0A6I9LS65
names: Similarity
messages: Belongs to the protein kinase superfamily.

230844:Ripk2
gene id: 230844:Ripk2
uniprot id: A0A6I9LGG3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family.
messages: Cytoplasm
messages: Found in a signaling complex consisting of at least ARHGEF2, NOD2 and RIPK2.
messages: Serine/threonine/tyrosine-protein kinase that plays an essential role in modulation of innate and adaptive immune responses. Acts as a key effector of NOD1 and NOD2 signaling pathways: upon activation by bacterial peptidoglycans, NOD1 and NOD2 oligomerize and recruit RIPK2 via CARD-CARD domains, leading to the formation of RIPK2 filaments.

230844:Maco1
gene id: 230844:Maco1
uniprot id: A0A6I9L2A8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the macoilin family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Nucleus membrane
messages: Plays a role in the regulation of neuronal activity.
messages: Rough endoplasmic reticulum membrane

230844:Emp2
gene id: 230844:Emp2
uniprot id: A0A6I9LXF6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Belongs to the PMP-22/EMP/MP20 family.
messages: Cell membrane
messages: Functions as a key regulator of cell membrane composition by regulating proteins surface expression. Also, plays a role in regulation of processes including cell migration, cell proliferation, cell contraction and cell adhesion.
messages: Golgi apparatus membrane
messages: Membrane
messages: Membrane raft
messages: Nucleus
messages: perinuclear region

230844:Wnt16
gene id: 230844:Wnt16
uniprot id: A0A6I9MI45
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

230844:Tmem132c
gene id: 230844:Tmem132c
uniprot id: A0A6I9KZL0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM132 family.
messages: Membrane

230844:Phc2
gene id: 230844:Phc2
uniprot id: A0A6I9MBL7
uniprot id: A0A6J0CQI1
names: Subcellular Location Annotation
messages: Nucleus

230844:Rbbp8
gene id: 230844:Rbbp8
uniprot id: A0A6I9M4M1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COM1/SAE2/CtIP family.
messages: Nucleus

230844:Pde4a
gene id: 230844:Pde4a
uniprot id: A0A6I9M3R5
uniprot id: A0A6J0DYE6
uniprot id: A0A6J0E088
uniprot id: A0A6J0E1H6
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family. PDE4 subfamily.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

230844:Sh2b1
gene id: 230844:Sh2b1
uniprot id: A0A6I9LAU1
uniprot id: A0A6I9LKT0
uniprot id: A0A6J0DHB5
uniprot id: A0A6J0DHC5
names: Similarity
messages: Belongs to the SH2B adapter family.

230844:Hspa13
gene id: 230844:Hspa13
uniprot id: A0A6I9LWU5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the heat shock protein 70 family.
messages: Binds UBQLN2.
messages: Endoplasmic reticulum
messages: Has peptide-independent ATPase activity.
messages: Microsome

230844:Nat9
gene id: 230844:Nat9
uniprot id: A0A6J0CXK8
names: Similarity
messages: Belongs to the acetyltransferase family. GNAT subfamily.

230844:Tprkb
gene id: 230844:Tprkb
uniprot id: A0A6I9MN99
names: Similarity
messages: Belongs to the CGI121/TPRKB family.

230844:Cdc37
gene id: 230844:Cdc37
uniprot id: A0A6I9LZD8
uniprot id: A0A6J0E1I6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDC37 family.
messages: Cytoplasm

230844:Rarg
gene id: 230844:Rarg
uniprot id: A0A6I9LTF7
uniprot id: A0A6J0DSV5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR1 subfamily.
messages: Nucleus

230844:Msh3
gene id: 230844:Msh3
uniprot id: A0A6I9LCP7
uniprot id: A0A6I9LK19
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.
messages: Component of the post-replicative DNA mismatch repair system (MMR).

230844:Spcs2
gene id: 230844:Spcs2
uniprot id: A0A6I9LU46
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPCS2 family.
messages: Component of the signal peptidase complex (SPC) which catalyzes the cleavage of N-terminal signal sequences from nascent proteins as they are translocated into the lumen of the endoplasmic reticulum. Enhances the enzymatic activity of SPC and facilitates the interactions between different components of the translocation site.
messages: Endoplasmic reticulum membrane
messages: Membrane

230844:Tnfsf9
gene id: 230844:Tnfsf9
uniprot id: A0A6I9LEL9
names: Similarity
messages: Belongs to the tumor necrosis factor family.

230844:Ppm1a
gene id: 230844:Ppm1a
uniprot id: A0A6I9M4V2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PP2C family.
messages: Membrane
messages: cytosol

230844:Ube2a
gene id: 230844:Ube2a
uniprot id: A0A6I9M050
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

230844:Mrps21
gene id: 230844:Mrps21
uniprot id: A0A6J0DUV2
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

230844:Camk4
gene id: 230844:Camk4
uniprot id: A0A6I9L6C0
names: Similarity
messages: Belongs to the protein kinase superfamily.

230844:Rell2
gene id: 230844:Rell2
uniprot id: A0A6I9LS28
names: Similarity
messages: Belongs to the RELT family.

230844:LOC102917736
gene id: 230844:LOC102917736
uniprot id: A0A6I9MDK0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:LOC102919474
gene id: 230844:LOC102919474
uniprot id: A0A6I9L4P3
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the organic matrix of bone and cartilage. Thought to act as an inhibitor of bone formation.
messages: Belongs to the osteocalcin/matrix Gla protein family.
messages: Gamma-carboxyglutamate residues are formed by vitamin K dependent carboxylation. These residues are essential for the binding of calcium.
messages: Requires vitamin K-dependent gamma-carboxylation for its function.
messages: Secreted

230844:Mtfr1l
gene id: 230844:Mtfr1l
uniprot id: A0A6I9LE02
uniprot id: A0A6J0D3G2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MTFR1 family.
messages: Mitochondrion
messages: Plays a role in mitochondrial aerobic respiration. Regulates mitochondrial organization and fission.

230844:LOC102918677
gene id: 230844:LOC102918677
uniprot id: A0A6I9MAC0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Tbc1d31
gene id: 230844:Tbc1d31
uniprot id: A0A6I9LZX4
uniprot id: A0A6J0EFD2
names: Function
names: Subcellular Location Annotation
messages: Molecular adapter which is involved in cilium biogenesis. Part of a functional complex including OFD1 a centriolar protein involved in cilium assembly. Could regulate the cAMP-dependent phosphorylation of OFD1, and its subsequent ubiquitination by PJA2 which ultimately leads to its proteasomal degradation.
messages: centriolar satellite
messages: cilium basal body

230844:Rps6ka3
gene id: 230844:Rps6ka3
uniprot id: A0A6I9KY27
uniprot id: A0A6I9KYB7
uniprot id: A0A6I9L523
uniprot id: A0A6J0CYF3
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily.

230844:LOC102928185
gene id: 230844:LOC102928185
uniprot id: A0A6J0CIJ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the argonaute family.
messages: P-body

230844:Stk32a
gene id: 230844:Stk32a
uniprot id: A0A6I9LEH9
names: Similarity
messages: Belongs to the protein kinase superfamily.

230844:Fabp7
gene id: 230844:Fabp7
uniprot id: A0A6I9LLL3
names: Similarity
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.

230844:Cdk5rap3
gene id: 230844:Cdk5rap3
uniprot id: A0A6I9L2L1
names: Similarity
messages: Belongs to the CDK5RAP3 family.

230844:Chst13
gene id: 230844:Chst13
uniprot id: A0A6I9MKK7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 2 family.
messages: Golgi apparatus membrane
messages: Membrane

230844:Bcl2l10
gene id: 230844:Bcl2l10
uniprot id: A0A6I9L6H6
names: Similarity
messages: Belongs to the Bcl-2 family.

230844:Acads
gene id: 230844:Acads
uniprot id: A0A6I9MKP2
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

230844:Atp10b
gene id: 230844:Atp10b
uniprot id: A0A6I9L1K8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.
messages: Membrane

230844:Dynlt5
gene id: 230844:Dynlt5
uniprot id: A0A6I9LNE7
uniprot id: A0A6J0E6U9
names: Similarity
messages: Belongs to the dynein light chain Tctex-type family.

230844:Nr1i2
gene id: 230844:Nr1i2
uniprot id: A0A6J0D3P9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

230844:Bmp15
gene id: 230844:Bmp15
uniprot id: A0A6I9MEQ7
names: Similarity
messages: Belongs to the TGF-beta family.

230844:Kel
gene id: 230844:Kel
uniprot id: A0A6I9MLH2
names: Subcellular Location Annotation
messages: Membrane

230844:LOC102911525
gene id: 230844:LOC102911525
uniprot id: A0A6I9M7E2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Tmprss5
gene id: 230844:Tmprss5
uniprot id: A0A6I9L9P0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

230844:Adra2c
gene id: 230844:Adra2c
uniprot id: A0A6I9LVQ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Alpha-2 adrenergic receptors mediate the catecholamine-induced inhibition of adenylate cyclase through the action of G proteins.
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Cdk7
gene id: 230844:Cdk7
uniprot id: A0A6I9LPE3
uniprot id: A0A6I9LV73
names: Similarity
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.

230844:Grem2
gene id: 230844:Grem2
uniprot id: A0A6I9MBE6
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DAN family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

230844:Map3k14
gene id: 230844:Map3k14
uniprot id: A0A6J0D5Z3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.
messages: Cytoplasm
messages: Lymphotoxin beta-activated kinase which seems to be exclusively involved in the activation of NF-kappa-B and its transcriptional activity.

230844:C1H10orf90
gene id: 230844:C1H10orf90
uniprot id: A0A6I9L4I4
uniprot id: A0A6J0D965
uniprot id: A0A6J0DDD1
names: Subcellular Location Annotation
messages: centrosome

230844:Hmgcll1
gene id: 230844:Hmgcll1
uniprot id: A0A6I9KZ71
names: Similarity
messages: Belongs to the HMG-CoA lyase family.

230844:Ppp2r2d
gene id: 230844:Ppp2r2d
uniprot id: A0A6I9M0U3
uniprot id: A0A6J0E364
uniprot id: A0A6J0E4S7
names: Similarity
messages: Belongs to the phosphatase 2A regulatory subunit B family.

230844:Hus1b
gene id: 230844:Hus1b
uniprot id: A0A6I9KWL0
names: Similarity
messages: Belongs to the HUS1 family.

230844:Imp3
gene id: 230844:Imp3
uniprot id: A0A6I9KUX1
names: Similarity
messages: Belongs to the universal ribosomal protein uS4 family.

230844:Ccr8
gene id: 230844:Ccr8
uniprot id: A0A6I9MLB1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

230844:Cd5
gene id: 230844:Cd5
uniprot id: A0A6J0CJR5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

230844:LOC102915035
gene id: 230844:LOC102915035
uniprot id: A0A6I9MEV3
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

230844:Foxd3
gene id: 230844:Foxd3
uniprot id: A0A6I9KZQ1
names: Subcellular Location Annotation
messages: Nucleus

230844:Foxm1
gene id: 230844:Foxm1
uniprot id: A0A6I9LPP7
uniprot id: A0A6J0E0R8
uniprot id: A0A6J0E413
uniprot id: A0A6J0E8K1
names: Subcellular Location Annotation
messages: Nucleus

230844:Gabbr2
gene id: 230844:Gabbr2
uniprot id: A0A6I9KZ39
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 3 family. GABA-B receptor subfamily.
messages: Cell membrane
messages: Membrane

230844:Phlda2
gene id: 230844:Phlda2
uniprot id: A0A6I9LDZ7
names: Subcellular Location Annotation
messages: Cytoplasm

230844:Ddx6
gene id: 230844:Ddx6
uniprot id: A0A6J0CJ79
names: Similarity
messages: Belongs to the DEAD box helicase family.

230844:Nkd1
gene id: 230844:Nkd1
uniprot id: A0A6I9KVD2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NKD family.
messages: Cell autonomous antagonist of the canonical Wnt signaling pathway.
messages: Cell membrane
messages: Cytoplasm

230844:Ppcs
gene id: 230844:Ppcs
uniprot id: A0A6I9M267
uniprot id: A0A6I9MDS5
names: Similarity
messages: Belongs to the PPC synthetase family.

230844:Rxfp2
gene id: 230844:Rxfp2
uniprot id: A0A6I9L9E4
names: Caution
names: Subcellular Location Annotation
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

230844:Sf3a2
gene id: 230844:Sf3a2
uniprot id: A0A6I9LJK2
names: Similarity
messages: Belongs to the SF3A2 family.

230844:Aebp1
gene id: 230844:Aebp1
uniprot id: A0A6I9KXL2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M14 family.
messages: Secreted

230844:Asb4
gene id: 230844:Asb4
uniprot id: A0A6I9LMY2
names: Similarity
messages: Belongs to the ankyrin SOCS box (ASB) family.

230844:Gtf2e1
gene id: 230844:Gtf2e1
uniprot id: A0A6J0D3P3
names: Function
names: Similarity
messages: Belongs to the TFIIE alpha subunit family.
messages: Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase.

230844:LOC102909657
gene id: 230844:LOC102909657
uniprot id: A0A6I9M6C1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Epc2
gene id: 230844:Epc2
uniprot id: A0A6I9L061
uniprot id: A0A6I9L7F1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enhancer of polycomb family.
messages: Nucleus

230844:Rock1
gene id: 230844:Rock1
uniprot id: A0A6I9M0Y6
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activated by RHOA binding. Inhibited by Y-27632.
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family.
messages: Cytoplasm
messages: Homodimer.
messages: Membrane
messages: Protein kinase which is a key regulator of actin cytoskeleton and cell polarity.

230844:Copg1
gene id: 230844:Copg1
uniprot id: A0A6I9MAK9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the COPG family.
messages: COPI-coated vesicle membrane
messages: Cytoplasm
messages: Golgi apparatus membrane
messages: Membrane
messages: Oligomeric complex.
messages: The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.

230844:Gnb4
gene id: 230844:Gnb4
uniprot id: A0A6J0DM54
names: Similarity
messages: Belongs to the WD repeat G protein beta family.

230844:Tspan3
gene id: 230844:Tspan3
uniprot id: A0A6I9KUX7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

230844:Med17
gene id: 230844:Med17
uniprot id: A0A6I9M571
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 17 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex, which is composed of MED1, MED4, MED6, MED7, MED8, MED9, MED10, MED11, MED12, MED13, MED13L, MED14, MED15, MED16, MED17, MED18, MED19, MED20, MED21, MED22, MED23, MED24, MED25, MED26, MED27, MED29, MED30, MED31, CCNC, CDK8 and CDC2L6/CDK11. The MED12, MED13, CCNC and CDK8 subunits form a distinct module termed the CDK8 module. Mediator containing the CDK8 module is less active than Mediator lacking this module in supporting transcriptional activation. Individual preparations of the Mediator complex lacking one or more distinct subunits have been variously termed ARC, CRSP, DRIP, PC2, SMCC and TRAP.
messages: Nucleus

230844:Pigh
gene id: 230844:Pigh
uniprot id: A0A6I9L4S9
uniprot id: A0A6I9L8D5
uniprot id: A0A6J0CYI3
names: Similarity
messages: Belongs to the PIGH family.

230844:LOC102928123
gene id: 230844:LOC102928123
uniprot id: A0A6I9LGZ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Ctu1
gene id: 230844:Ctu1
uniprot id: A0A6J0DZE5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TtcA family. CTU1/NCS6/ATPBD3 subfamily.
messages: Component of a complex at least composed of URM1, CTU2/NCS2 and CTU1/ATPBD3. May form a heterodimer with CTU2/NCS2.
messages: Cytoplasm
messages: Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Directly binds tRNAs and probably acts by catalyzing adenylation of tRNAs, an intermediate required for 2-thiolation. It is unclear whether it acts as a sulfurtransferase that transfers sulfur from thiocarboxylated URM1 onto the uridine of tRNAs at wobble position.

230844:Itk
gene id: 230844:Itk
uniprot id: A0A6I9MM04
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.
messages: Cytoplasm

230844:LOC102928693
gene id: 230844:LOC102928693
uniprot id: A0A6I9LDE8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IL-6 superfamily.
messages: Secreted

230844:Akap4
gene id: 230844:Akap4
uniprot id: A0A6I9MHP2
uniprot id: A0A6I9MJX4
names: Similarity
messages: Belongs to the AKAP110 family.

230844:Nr0b1
gene id: 230844:Nr0b1
uniprot id: A0A6I9M4W0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR0 subfamily.
messages: Cytoplasm
messages: Nucleus
messages: Orphan nuclear receptor. Component of a cascade required for the development of the hypothalamic-pituitary-adrenal-gonadal axis. Acts as a coregulatory protein that inhibits the transcriptional activity of other nuclear receptors through heterodimeric interactions. May also have a role in the development of the embryo and in the maintenance of embryonic stem cell pluripotency.

230844:LOC102918455
gene id: 230844:LOC102918455
uniprot id: A0A6I9LCX4
names: Function
names: Similarity
messages: Belongs to the ferritin family.
messages: Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation.

230844:Tk2
gene id: 230844:Tk2
uniprot id: A0A6I9LG06
uniprot id: A0A6J0DC98
names: Similarity
messages: Belongs to the DCK/DGK family.

230844:Rcan2
gene id: 230844:Rcan2
uniprot id: A0A6J0EC20
names: Function
names: Similarity
messages: Belongs to the RCAN family.
messages: Inhibits calcineurin-dependent transcriptional responses by binding to the catalytic domain of calcineurin A. Could play a role during central nervous system development.

230844:LOC102920919
gene id: 230844:LOC102920919
uniprot id: A0A6I9MKN3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Ncapd2
gene id: 230844:Ncapd2
uniprot id: A0A6I9LX74
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CND1 (condensin subunit 1) family.
messages: Chromosome
messages: Nucleus
messages: Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases.

230844:St3gal4
gene id: 230844:St3gal4
uniprot id: A0A6I9LIG5
uniprot id: A0A6I9LNE5
uniprot id: A0A6J0DLG4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

230844:Ctu2
gene id: 230844:Ctu2
uniprot id: A0A6I9LZB5
uniprot id: A0A6J0E7G4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CTU2/NCS2 family.
messages: Component of a complex at least composed of URM1, CTU2/NCS2 and CTU1/ATPBD3.
messages: Cytoplasm
messages: Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln). May act by forming a heterodimer with CTU1/ATPBD3 that ligates sulfur from thiocarboxylated URM1 onto the uridine of tRNAs at wobble position.

230844:Lix1
gene id: 230844:Lix1
uniprot id: A0A6I9LEM4
names: Similarity
messages: Belongs to the LIX1 family.

230844:Washc5
gene id: 230844:Washc5
uniprot id: A0A6I9LZV2
names: Similarity
messages: Belongs to the strumpellin family.

230844:Kifc1
gene id: 230844:Kifc1
uniprot id: A0A6I9MCV4
uniprot id: A0A6J0CSS8
uniprot id: A0A6J0CV29
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

230844:LOC102908473
gene id: 230844:LOC102908473
uniprot id: A0A6J0DKI8
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS27 family.

230844:LOC102904685
gene id: 230844:LOC102904685
uniprot id: A0A6J0E754
names: Similarity
messages: Belongs to the PRAME family.

230844:Nr1d2
gene id: 230844:Nr1d2
uniprot id: A0A6I9L974
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

230844:Rab9b
gene id: 230844:Rab9b
uniprot id: A0A6J0CVY9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Membrane
messages: phagosome membrane

230844:Pigw
gene id: 230844:Pigw
uniprot id: A0A6J0DMT4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PIGW family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Probable acetyltransferase, which acetylates the inositol ring of phosphatidylinositol during biosynthesis of GPI-anchor.

230844:Dock7
gene id: 230844:Dock7
uniprot id: A0A6J0CYS3
names: Similarity
messages: Belongs to the DOCK family.

230844:Ncoa7
gene id: 230844:Ncoa7
uniprot id: A0A6I9LMM9
uniprot id: A0A6J0DHC9
names: Similarity
messages: Belongs to the OXR1 family.

230844:Bloc1s1
gene id: 230844:Bloc1s1
uniprot id: A0A6I9LZ73
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BLOC1S1 family.
messages: Lysosome membrane
messages: May negatively regulate aerobic respiration through mitochondrial protein lysine-acetylation. May counteract the action of the deacetylase SIRT3 by acetylating and regulating proteins of the mitochondrial respiratory chain including ATP5F1A and NDUFA9.
messages: Mitochondrion intermembrane space

230844:S100g
gene id: 230844:S100g
uniprot id: A0A6I9L5A0
names: Similarity
messages: Belongs to the S-100 family.

230844:Immp2l
gene id: 230844:Immp2l
uniprot id: A0A6I9M4M6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S26 family. IMP2 subfamily.
messages: Catalyzes the removal of transit peptides required for the targeting of proteins from the mitochondrial matrix, across the inner membrane, into the inter-membrane space. Known to process the nuclear encoded protein DIABLO.
messages: Heterodimer of 2 subunits, IMMPL1 and IMMPL2.
messages: Membrane
messages: Mitochondrion inner membrane

230844:Rps28
gene id: 230844:Rps28
uniprot id: A0A6J0EA27
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS28 family.

230844:Syt1
gene id: 230844:Syt1
uniprot id: A0A6J0D1G4
uniprot id: A0A6J0D5G8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptotagmin family.
messages: Binds 3 Ca(2+) ions per subunit. The ions are bound to the C2 domains.
messages: May have a regulatory role in the membrane interactions during trafficking of synaptic vesicles at the active zone of the synapse. It binds acidic phospholipids with a specificity that requires the presence of both an acidic head group and a diacyl backbone.
messages: synaptic vesicle membrane

230844:Tmprss7
gene id: 230844:Tmprss7
uniprot id: A0A6I9LAM9
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

230844:LOC102914778
gene id: 230844:LOC102914778
uniprot id: A0A6I9LYI5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.
messages: cytoskeleton

230844:LOC102922613
gene id: 230844:LOC102922613
uniprot id: A0A6I9M3K4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Med10
gene id: 230844:Med10
uniprot id: A0A6I9M5H3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 10 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex, which is composed of MED1, MED4, MED6, MED7, MED8, MED9, MED10, MED11, MED12, MED13, MED13L, MED14, MED15, MED16, MED17, MED18, MED19, MED20, MED21, MED22, MED23, MED24, MED25, MED26, MED27, MED29, MED30, MED31, CCNC, CDK8 and CDC2L6/CDK11. The MED12, MED13, CCNC and CDK8 subunits form a distinct module termed the CDK8 module. Mediator containing the CDK8 module is less active than Mediator lacking this module in supporting transcriptional activation. Individual preparations of the Mediator complex lacking one or more distinct subunits have been variously termed ARC, CRSP, DRIP, PC2, SMCC and TRAP.
messages: Nucleus

230844:Irf4
gene id: 230844:Irf4
uniprot id: A0A6I9L3B2
names: Subcellular Location Annotation
messages: Nucleus

230844:LOC102927452
gene id: 230844:LOC102927452
uniprot id: A0A6I9MCZ9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2B family.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

230844:Xrcc6
gene id: 230844:Xrcc6
uniprot id: A0A6I9LC37
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ku70 family.
messages: Nucleus

230844:Tmbim4
gene id: 230844:Tmbim4
uniprot id: A0A6I9L5J8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

230844:Dclk2
gene id: 230844:Dclk2
uniprot id: A0A6I9L4J0
uniprot id: A0A6I9LBW9
uniprot id: A0A6J0D5K3
uniprot id: A0A6J0D6R2
uniprot id: A0A6J0D7A8
uniprot id: A0A6J0D7S2
uniprot id: A0A6J0DBT5
uniprot id: A0A6J0DBU0
names: Similarity
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. CaMK subfamily.

230844:Pola2
gene id: 230844:Pola2
uniprot id: A0A6I9LD56
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Accessory subunit of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which plays an essential role in the initiation of DNA synthesis.
messages: Belongs to the DNA polymerase alpha subunit B family.
messages: Nucleus

230844:Toe1
gene id: 230844:Toe1
uniprot id: A0A6I9LXR9
names: Similarity
messages: Belongs to the CAF1 family.

230844:Smim22
gene id: 230844:Smim22
uniprot id: A0A6J0DS07
uniprot id: A0A6J0DUR0
names: Subcellular Location Annotation
messages: Membrane

230844:Pkib
gene id: 230844:Pkib
uniprot id: A0A6J0DQS7
names: Function
names: Similarity
messages: Belongs to the PKI family.
messages: Extremely potent competitive inhibitor of cAMP-dependent protein kinase activity, this protein interacts with the catalytic subunit of the enzyme after the cAMP-induced dissociation of its regulatory chains.

230844:Zfpl1
gene id: 230844:Zfpl1
uniprot id: A0A6J0DNQ0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ZFPL1 family.
messages: Interacts with GOLGA2/GM130.
messages: Membrane
messages: Required for cis-Golgi integrity and efficient ER to Golgi transport.
messages: The B box-type and RING-type zinc fingers although degenerate play a central role in function of the protein.
messages: cis-Golgi network membrane

230844:Paip2
gene id: 230844:Paip2
uniprot id: A0A6I9MBK2
names: Similarity
messages: Belongs to the PAIP2 family.

230844:Nup205
gene id: 230844:Nup205
uniprot id: A0A6I9M4Y7
names: Similarity
messages: Belongs to the NUP186/NUP192/NUP205 family.

230844:Camsap1
gene id: 230844:Camsap1
uniprot id: A0A6I9LDS1
uniprot id: A0A6I9LM03
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CAMSAP1 family.
messages: The CKK domain binds microtubules.
messages: cytoskeleton

230844:LOC102912139
gene id: 230844:LOC102912139
uniprot id: A0A6I9LMK6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

230844:Ndufb1
gene id: 230844:Ndufb1
uniprot id: A0A6I9M0A5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFB1 subunit family.
messages: Complex I is composed of 45 different subunits.
messages: Mitochondrion inner membrane

230844:Hspb6
gene id: 230844:Hspb6
uniprot id: A0A6I9LTW9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small heat shock protein (HSP20) family.
messages: Nucleus

230844:Minpp1
gene id: 230844:Minpp1
uniprot id: A0A6I9M506
names: Similarity
messages: Belongs to the histidine acid phosphatase family. MINPP1 subfamily.

230844:Mical1
gene id: 230844:Mical1
uniprot id: A0A6J0DVH4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Mical family.
messages: Cytoplasm

230844:LOC102902765
gene id: 230844:LOC102902765
uniprot id: A0A6I9MHL8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:LOC102903459
gene id: 230844:LOC102903459
uniprot id: A0A6I9M7Q5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Supt6h
gene id: 230844:Supt6h
uniprot id: A0A6I9LE23
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPT6 family.
messages: Nucleus
messages: Transcription elongation factor that enhances transcription elongation by RNA polymerase II (RNAPII).

230844:Cndp1
gene id: 230844:Cndp1
uniprot id: A0A6J0E799
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M20A family.
messages: Binds 2 manganese ions per subunit.

230844:LOC102920092
gene id: 230844:LOC102920092
uniprot id: A0A6I9MLX6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:LOC102916086
gene id: 230844:LOC102916086
uniprot id: A0A6J0CWN5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Padi6
gene id: 230844:Padi6
uniprot id: A0A6I9LDM1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein arginine deiminase family.
messages: Catalyzes the deimination of arginine residues of proteins.
messages: Cytoplasm

230844:Bcar1
gene id: 230844:Bcar1
uniprot id: A0A6I9KZR0
uniprot id: A0A6I9KZS5
uniprot id: A0A6I9L747
uniprot id: A0A6J0CZP4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CAS family.
messages: focal adhesion

230844:LOC102905502
gene id: 230844:LOC102905502
uniprot id: A0A6I9LT40
uniprot id: A0A6I9LYH9
names: Similarity
messages: Belongs to the vasopressin/oxytocin family.

230844:Dnah17
gene id: 230844:Dnah17
uniprot id: A0A6I9LTV2
names: Similarity
messages: Belongs to the dynein heavy chain family.

230844:Nsrp1
gene id: 230844:Nsrp1
uniprot id: A0A6I9L5D3
uniprot id: A0A6I9LI22
names: Similarity
messages: Belongs to the NSRP1 family.

230844:Nup188
gene id: 230844:Nup188
uniprot id: A0A6I9LIJ6
names: Subcellular Location Annotation
messages: nuclear pore complex

230844:Nmt2
gene id: 230844:Nmt2
uniprot id: A0A6I9LWI7
uniprot id: A0A6I9M1H8
names: Function
names: Similarity
messages: Adds a myristoyl group to the N-terminal glycine residue of certain cellular proteins.
messages: Belongs to the NMT family.

230844:Pclaf
gene id: 230844:Pclaf
uniprot id: A0A6I9LAD4
names: Subcellular Location Annotation
messages: Nucleus
messages: perinuclear region

230844:Dcst2
gene id: 230844:Dcst2
uniprot id: A0A6I9LBY8
names: Subcellular Location Annotation
messages: Membrane

230844:Spdya
gene id: 230844:Spdya
uniprot id: A0A6I9MB02
names: Similarity
messages: Belongs to the Speedy/Ringo family.

230844:LOC102918996
gene id: 230844:LOC102918996
uniprot id: A0A6J0DLP1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 11 family.
messages: Golgi stack membrane
messages: Membrane

230844:Ano3
gene id: 230844:Ano3
uniprot id: A0A6I9LDF6
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anoctamin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

230844:Il17rd
gene id: 230844:Il17rd
uniprot id: A0A6I9LM01
uniprot id: A0A6J0DI37
names: Subcellular Location Annotation
messages: Membrane

230844:Slc15a1
gene id: 230844:Slc15a1
uniprot id: A0A6I9LKU8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Apical cell membrane
messages: Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.
messages: Interacts (via extracellular domain region) with trypsin.
messages: Membrane

230844:Smarcd2
gene id: 230844:Smarcd2
uniprot id: A0A6I9L2C0
names: Similarity
messages: Belongs to the SMARCD family.

230844:Myod1
gene id: 230844:Myod1
uniprot id: A0A6I9MDS7
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Efficient DNA binding requires dimerization with another bHLH protein.
messages: Induces fibroblasts to differentiate into myoblasts. Acts as a transcriptional activator that promotes transcription of muscle-specific target genes and plays a role in muscle differentiation.
messages: Nucleus

230844:Rnaset2
gene id: 230844:Rnaset2
uniprot id: A0A6I9L2S8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase T2 family.
messages: Lysosome lumen

230844:Exosc3
gene id: 230844:Exosc3
uniprot id: A0A6I9LLH5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRP40 family.
messages: Cytoplasm
messages: nucleolus

230844:Il20
gene id: 230844:Il20
uniprot id: A0A6I9MHD8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IL-10 family.
messages: Immune regulatory cytokine.
messages: Secreted

230844:LOC102907703
gene id: 230844:LOC102907703
uniprot id: A0A6I9M6J8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:LOC107400023
gene id: 230844:LOC107400023
uniprot id: A0A6J0CTD5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Isx
gene id: 230844:Isx
uniprot id: A0A6I9L8V4
names: Subcellular Location Annotation
messages: Nucleus

230844:Nf2
gene id: 230844:Nf2
uniprot id: A0A6I9KXU3
uniprot id: A0A6J0CVN4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: cytoskeleton

230844:Tent5c
gene id: 230844:Tent5c
uniprot id: A0A6J0E992
names: Similarity
messages: Belongs to the TENT family.

230844:Rwdd3
gene id: 230844:Rwdd3
uniprot id: A0A6I9L665
uniprot id: A0A6I9LF71
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

230844:Npc1
gene id: 230844:Npc1
uniprot id: A0A6J0E878
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the patched family.
messages: Membrane

230844:LOC102920352
gene id: 230844:LOC102920352
uniprot id: A0A6J0ECQ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Mmgt1
gene id: 230844:Mmgt1
uniprot id: A0A6I9LX05
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane magnesium transporter (TC 1.A.67) family.
messages: Early endosome membrane
messages: Endosome membrane
messages: Golgi apparatus membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the endoplasmic reticulum membrane protein complex (EMC) that enables the energy-independent insertion into endoplasmic reticulum membranes of newly synthesized membrane proteins. May be involved in Mg(2+) transport.

230844:Spats2
gene id: 230844:Spats2
uniprot id: A0A6I9L7S0
names: Similarity
messages: Belongs to the SPATS2 family.

230844:Vti1b
gene id: 230844:Vti1b
uniprot id: A0A6I9KY47
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VTI1 family.
messages: Membrane

230844:Ndufa13
gene id: 230844:Ndufa13
uniprot id: A0A6J0CPB1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I NDUFA13 subunit family.
messages: Complex I functions in the transfer of electrons from NADH to the respiratory chain. Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis.
messages: Mitochondrion inner membrane

230844:Plpp4
gene id: 230844:Plpp4
uniprot id: A0A6I9L5P2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PA-phosphatase related phosphoesterase family.
messages: Membrane

230844:Gpr12
gene id: 230844:Gpr12
uniprot id: A0A6I9LN16
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Adgrl4
gene id: 230844:Adgrl4
uniprot id: A0A6I9LSG4
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 2 family. Adhesion G-protein coupled receptor (ADGR) subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

230844:Papss1
gene id: 230844:Papss1
uniprot id: A0A6I9L1Z0
names: Similarity
messages: In the C-terminal section; belongs to the sulfate adenylyltransferase family.
messages: In the N-terminal section; belongs to the APS kinase family.

230844:LOC102924454
gene id: 230844:LOC102924454
uniprot id: A0A6I9LQE9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:LOC102904506
gene id: 230844:LOC102904506
uniprot id: A0A6I9MDK8
names: Similarity
messages: Belongs to the glycosyl hydrolase 22 family.

230844:LOC102928052
gene id: 230844:LOC102928052
uniprot id: A0A6I9MFG5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H4 family.
messages: Chromosome
messages: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

230844:Abcb11
gene id: 230844:Abcb11
uniprot id: A0A6J0CN58
names: Subcellular Location Annotation
messages: Membrane

230844:Kcna7
gene id: 230844:Kcna7
uniprot id: A0A6I9LLY5
names: Subcellular Location Annotation
messages: Membrane

230844:Hnf1a
gene id: 230844:Hnf1a
uniprot id: A0A6I9MIG4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HNF1 homeobox family.
messages: Nucleus

230844:Asb5
gene id: 230844:Asb5
uniprot id: A0A6I9KTN4
uniprot id: A0A6I9L068
uniprot id: A0A6I9L0D2
names: Similarity
messages: Belongs to the ankyrin SOCS box (ASB) family.

230844:LOC102925635
gene id: 230844:LOC102925635
uniprot id: A0A6I9M7P1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Dgkd
gene id: 230844:Dgkd
uniprot id: A0A6J0DQL9
names: Similarity
messages: Belongs to the eukaryotic diacylglycerol kinase family.

230844:Wdr12
gene id: 230844:Wdr12
uniprot id: A0A6J0D7I9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the WD repeat WDR12/YTM1 family.
messages: Component of the PeBoW complex, composed of BOP1, PES1 and WDR12. Within the PeBoW complex BOP1 interacts directly with PES1 and WDR12. The PeBoW complex also associates with the 66S pre-ribosome.
messages: Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome.
messages: nucleolus
messages: nucleoplasm

230844:Vps13a
gene id: 230844:Vps13a
uniprot id: A0A6I9KS54
uniprot id: A0A6I9KYR7
uniprot id: A0A6I9L1I0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VPS13 family.
messages: Lipid droplet

230844:Pcsk9
gene id: 230844:Pcsk9
uniprot id: A0A6I9LZU0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S8 family.
messages: Cell surface
messages: Cytoplasm
messages: Endoplasmic reticulum
messages: Endosome
messages: Golgi apparatus
messages: Lysosome

230844:Cklf
gene id: 230844:Cklf
uniprot id: A0A6I9L8P8
names: Subcellular Location Annotation
messages: Membrane

230844:Kcnj4
gene id: 230844:Kcnj4
uniprot id: A0A6J0DCF3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family.
messages: Membrane

230844:Cadm3
gene id: 230844:Cadm3
uniprot id: A0A6I9LUG2
uniprot id: A0A6I9MAR6
names: Similarity
messages: Belongs to the nectin family.

230844:Cuedc2
gene id: 230844:Cuedc2
uniprot id: A0A6I9LQE1
uniprot id: A0A6J0E3I3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CUEDC2 family.
messages: Cytoplasm
messages: Nucleus

230844:Appl1
gene id: 230844:Appl1
uniprot id: A0A6J0DKZ2
names: Subcellular Location Annotation
messages: Early endosome membrane
messages: Endosome membrane
messages: Membrane
messages: Nucleus
messages: phagosome
messages: ruffle

230844:Foxf2
gene id: 230844:Foxf2
uniprot id: A0A6I9L316
names: Subcellular Location Annotation
messages: Nucleus

230844:Ufl1
gene id: 230844:Ufl1
uniprot id: A0A6I9LHG4
names: Similarity
messages: Belongs to the UFL1 family.

230844:Vps16
gene id: 230844:Vps16
uniprot id: A0A6I9LIM3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VPS16 family.
messages: Early endosome
messages: Late endosome membrane
messages: Lysosome membrane
messages: Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes.
messages: Vesicle

230844:Paqr3
gene id: 230844:Paqr3
uniprot id: A0A6I9L9Q3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ADIPOR family.
messages: Membrane

230844:Cadm1
gene id: 230844:Cadm1
uniprot id: A0A6I9L9Q5
uniprot id: A0A6I9LJL3
uniprot id: A0A6I9LNE0
names: Similarity
messages: Belongs to the nectin family.

230844:Foxi2
gene id: 230844:Foxi2
uniprot id: A0A6I9LZL2
names: Subcellular Location Annotation
messages: Nucleus

230844:Tmem200c
gene id: 230844:Tmem200c
uniprot id: A0A6J0ED93
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM200 family.
messages: Membrane

230844:Lnpk
gene id: 230844:Lnpk
uniprot id: A0A6J0CPV5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the lunapark family.
messages: Endoplasmic reticulum membrane
messages: Homodimer; homodimerization requires the C4-type zinc finger motif and decreases during mitosis in a phosphorylation-dependent manner.
messages: Plays a role in determining ER morphology.
messages: The C4-type zinc finger motif is necessary both for its ER three-way tubular junction localization and formation.

230844:Nxph1
gene id: 230844:Nxph1
uniprot id: A0A6J0E682
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the neurexophilin family.
messages: May be signaling molecules that resemble neuropeptides.
messages: Secreted

230844:Dpcd
gene id: 230844:Dpcd
uniprot id: A0A6I9M0L2
names: Similarity
messages: Belongs to the DPCD family.

230844:Irf5
gene id: 230844:Irf5
uniprot id: A0A6J0DKD3
names: Subcellular Location Annotation
messages: Nucleus

230844:Paip2b
gene id: 230844:Paip2b
uniprot id: A0A6I9LW31
names: Similarity
messages: Belongs to the PAIP2 family.

230844:Gimap8
gene id: 230844:Gimap8
uniprot id: A0A6I9MK00
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily.

230844:Cnih3
gene id: 230844:Cnih3
uniprot id: A0A6I9L7B3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cornichon family.
messages: Membrane

230844:Pcsk2
gene id: 230844:Pcsk2
uniprot id: A0A6I9LSG9
names: Similarity
messages: Belongs to the peptidase S8 family.

230844:Wasf3
gene id: 230844:Wasf3
uniprot id: A0A6J0DFM0
uniprot id: A0A6J0DL24
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SCAR/WAVE family.
messages: Binds actin and the Arp2/3 complex.
messages: Downstream effector molecule involved in the transmission of signals from tyrosine kinase receptors and small GTPases to the actin cytoskeleton. Promotes formation of actin filaments. Part of the WAVE complex that regulates lamellipodia formation. The WAVE complex regulates actin filament reorganization via its interaction with the Arp2/3 complex.
messages: cytoskeleton

230844:Prune1
gene id: 230844:Prune1
uniprot id: A0A6I9LF10
uniprot id: A0A6J0DKZ8
names: Similarity
messages: Belongs to the PPase class C family. Prune subfamily.

230844:Fam216a
gene id: 230844:Fam216a
uniprot id: A0A6I9L2Y1
names: Similarity
messages: Belongs to the FAM216 family.

230844:Il13ra1
gene id: 230844:Il13ra1
uniprot id: A0A6I9LYV2
names: Subcellular Location Annotation
messages: Membrane

230844:LOC102921075
gene id: 230844:LOC102921075
uniprot id: A0A6J0D2Q2
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

230844:Naa60
gene id: 230844:Naa60
uniprot id: A0A6I9LTI5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetyltransferase family. NAA60 subfamily.
messages: Golgi apparatus membrane

230844:Runx3
gene id: 230844:Runx3
uniprot id: A0A6J0D5L6
names: Function
names: Subcellular Location Annotation
messages: Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'-TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX.
messages: Nucleus

230844:Stum
gene id: 230844:Stum
uniprot id: A0A6I9KZY9
uniprot id: A0A6J0CZ25
names: Subcellular Location Annotation
messages: Membrane

230844:Lhx3
gene id: 230844:Lhx3
uniprot id: A0A6I9LDR6
uniprot id: A0A6I9LL36
names: Subcellular Location Annotation
messages: Nucleus

230844:Clcn6
gene id: 230844:Clcn6
uniprot id: A0A6I9M7X2
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chloride channel (TC 2.A.49) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

230844:LOC102920776
gene id: 230844:LOC102920776
uniprot id: A0A6I9KXK5
uniprot id: A0A6J0D0Y3
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZNRF3 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

230844:Pcmt1
gene id: 230844:Pcmt1
uniprot id: A0A6I9LIH0
uniprot id: A0A6J0DSW1
names: Similarity
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.

230844:Riox2
gene id: 230844:Riox2
uniprot id: A0A6I9LNG9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ROX family. MINA53 subfamily.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Nucleus
messages: Oxygenase that can act as both a histone lysine demethylase and a ribosomal histidine hydroxylase.

230844:Timm21
gene id: 230844:Timm21
uniprot id: A0A6I9LQR2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TIM21 family.
messages: Component of the TIM23 complex.
messages: Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane.
messages: Membrane
messages: Mitochondrion inner membrane
messages: Mitochondrion membrane
messages: Participates in the translocation of transit peptide-containing proteins across the mitochondrial inner membrane. Also required for assembly of mitochondrial respiratory chain complex I and complex IV as component of the MITRAC (mitochondrial translation regulation assembly intermediate of cytochrome c oxidase complex) complex. Probably shuttles between the presequence translocase and respiratory-chain assembly intermediates in a process that promotes incorporation of early nuclear-encoded subunits into these complexes.

230844:F2rl3
gene id: 230844:F2rl3
uniprot id: A0A6I9LY83
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

230844:Scn3a
gene id: 230844:Scn3a
uniprot id: A0A6I9L4W2
uniprot id: A0A6I9LDD8
uniprot id: A0A6I9LDH9
uniprot id: A0A6I9LHD3
uniprot id: A0A6J0D7D5
uniprot id: A0A6J0D939
uniprot id: A0A6J0D9M0
uniprot id: A0A6J0DDV9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium channel (TC 1.A.1.10) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient.
messages: Membrane

230844:LOC102904407
gene id: 230844:LOC102904407
uniprot id: A0A6I9MJ56
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Ebf3
gene id: 230844:Ebf3
uniprot id: A0A6I9LZL6
uniprot id: A0A6J0DZZ8
uniprot id: A0A6J0E002
uniprot id: A0A6J0E1R0
uniprot id: A0A6J0E1R5
uniprot id: A0A6J0E353
uniprot id: A0A6J0E358
uniprot id: A0A6J0E4S1
uniprot id: A0A6J0E7W9
uniprot id: A0A6J0E7X3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COE family.
messages: Nucleus

230844:Rpl12
gene id: 230844:Rpl12
uniprot id: A0A6I9M755
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Binds directly to 26S ribosomal RNA.

230844:LOC102921592
gene id: 230844:LOC102921592
uniprot id: A0A6I9MDA6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Cdipt
gene id: 230844:Cdipt
uniprot id: A0A6I9LD86
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

230844:Mrps31
gene id: 230844:Mrps31
uniprot id: A0A6I9LVQ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mS31 family.
messages: Mitochondrion

230844:Rnd3
gene id: 230844:Rnd3
uniprot id: A0A6I9L7E6
names: Function
messages: Binds GTP but lacks intrinsic GTPase activity and is resistant to Rho-specific GTPase-activating proteins.

230844:Jagn1
gene id: 230844:Jagn1
uniprot id: A0A6I9MP97
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the jagunal family.
messages: Endoplasmic reticulum membrane
messages: Membrane

230844:Mthfs
gene id: 230844:Mthfs
uniprot id: A0A6I9M8E0
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

230844:Mrps27
gene id: 230844:Mrps27
uniprot id: A0A6I9M8Q3
names: Subcellular Location Annotation
messages: Mitochondrion

230844:Cnpy1
gene id: 230844:Cnpy1
uniprot id: A0A6I9MI91
names: Similarity
messages: Belongs to the canopy family.

230844:Dkk4
gene id: 230844:Dkk4
uniprot id: A0A6I9LG16
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dickkopf family.
messages: Secreted

230844:Krtcap3
gene id: 230844:Krtcap3
uniprot id: A0A6J0CQ87
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM54 family.
messages: Membrane

230844:Smarca1
gene id: 230844:Smarca1
uniprot id: A0A6I9M298
uniprot id: A0A6I9M9U4
uniprot id: A0A6I9MDV8
uniprot id: A0A6J0CM93
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNF2/RAD54 helicase family. ISWI subfamily.
messages: Nucleus

230844:Fam234b
gene id: 230844:Fam234b
uniprot id: A0A6I9L3T7
uniprot id: A0A6J0D706
names: Similarity
messages: Belongs to the FAM234 family.

230844:Cdc6
gene id: 230844:Cdc6
uniprot id: A0A6I9L200
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDC6/cdc18 family.
messages: Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated.
messages: Nucleus

230844:LOC102905612
gene id: 230844:LOC102905612
uniprot id: A0A6I9LZ36
names: Similarity
messages: Belongs to the PRAME family.

230844:LOC102914502
gene id: 230844:LOC102914502
uniprot id: A0A6I9LZZ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the intercrine alpha (chemokine CxC) family.
messages: Secreted

230844:Gmnn
gene id: 230844:Gmnn
uniprot id: A0A6I9L4U7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the geminin family.
messages: Nucleus

230844:Slc1a6
gene id: 230844:Slc1a6
uniprot id: A0A6I9M5R6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Membrane

230844:Aldh8a1
gene id: 230844:Aldh8a1
uniprot id: A0A6I9LK89
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

230844:Mcidas
gene id: 230844:Mcidas
uniprot id: A0A6I9LRD5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the geminin family.
messages: Nucleus

230844:Lgi3
gene id: 230844:Lgi3
uniprot id: A0A6I9M7Z8
names: Subcellular Location Annotation
messages: Secreted

230844:Bcan
gene id: 230844:Bcan
uniprot id: A0A6J0D5G5
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aggrecan/versican proteoglycan family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

230844:Dnmt3l
gene id: 230844:Dnmt3l
uniprot id: A0A6I9M8L6
names: Subcellular Location Annotation
messages: Nucleus

230844:LOC102914701
gene id: 230844:LOC102914701
uniprot id: A0A6I9MG45
names: Similarity
messages: Belongs to the 'GDXG' lipolytic enzyme family.

230844:LOC102918152
gene id: 230844:LOC102918152
uniprot id: A0A6J0D8Z6
names: Similarity
messages: Belongs to the FAM47 family.

230844:Csad
gene id: 230844:Csad
uniprot id: A0A6I9LTG3
uniprot id: A0A6J0DJ21
names: Similarity
names: Subunit
messages: Belongs to the group II decarboxylase family.
messages: Homodimer.

230844:Lin52
gene id: 230844:Lin52
uniprot id: A0A6J0DVN4
names: Similarity
messages: Belongs to the lin-52 family.

230844:Slc9a5
gene id: 230844:Slc9a5
uniprot id: A0A6I9LQU5
uniprot id: A0A6J0DXT2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.
messages: Cell membrane
messages: Membrane
messages: Recycling endosome membrane

230844:Cog2
gene id: 230844:Cog2
uniprot id: A0A6I9M9R7
uniprot id: A0A6J0CGS0
names: Similarity
messages: Belongs to the COG2 family.

230844:Acsm2b
gene id: 230844:Acsm2b
uniprot id: A0A6I9LNE8
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

230844:Gpr84
gene id: 230844:Gpr84
uniprot id: A0A6I9LML7
names: Subcellular Location Annotation
messages: Membrane

230844:Mre11
gene id: 230844:Mre11
uniprot id: A0A6J0E7J8
uniprot id: A0A6J0EF33
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MRE11/RAD32 family.
messages: Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing.
messages: Nucleus

230844:LOC102910758
gene id: 230844:LOC102910758
uniprot id: A0A6I9M8D2
names: Similarity
messages: Belongs to the cytochrome P450 family.

230844:LOC107401573
gene id: 230844:LOC107401573
uniprot id: A0A6J0DGH4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Adhfe1
gene id: 230844:Adhfe1
uniprot id: A0A6I9L8B3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the iron-containing alcohol dehydrogenase family. Hydroxyacid-oxoacid transhydrogenase subfamily.
messages: Mitochondrion

230844:LOC102925363
gene id: 230844:LOC102925363
uniprot id: A0A6I9LHS0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Rab38
gene id: 230844:Rab38
uniprot id: A0A6I9LKS3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Membrane
messages: The small GTPases Rab are key regulators in vesicle trafficking.

230844:Krt18
gene id: 230844:Krt18
uniprot id: A0A6I9LP01
names: Similarity
messages: Belongs to the intermediate filament family.

230844:Plg
gene id: 230844:Plg
uniprot id: A0A6I9LFJ8
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S1 family. Plasminogen subfamily.
messages: Converted into plasmin by plasminogen activators, both plasminogen and its activator being bound to fibrin.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plasmin dissolves the fibrin of blood clots and acts as a proteolytic factor in a variety of other processes including embryonic development, tissue remodeling, tumor invasion, and inflammation. In ovulation, weakens the walls of the Graafian follicle. It activates the urokinase-type plasminogen activator, collagenases and several complement zymogens, such as C1 and C5. Cleavage of fibronectin and laminin leads to cell detachment and apoptosis. Also cleaves fibrin, thrombospondin and von Willebrand factor. Its role in tissue remodeling and tumor invasion may be modulated by CSPG4. Binds to cells.
messages: Secreted

230844:Dll3
gene id: 230844:Dll3
uniprot id: A0A6I9LXB4
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

230844:Slc31a1
gene id: 230844:Slc31a1
uniprot id: A0A6J0DDD9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the copper transporter (Ctr) (TC 1.A.56) family. SLC31A subfamily.
messages: Endosome membrane
messages: Late endosome membrane
messages: Membrane

230844:Slc35c1
gene id: 230844:Slc35c1
uniprot id: A0A6I9M2M6
uniprot id: A0A6I9ME86
names: Subcellular Location Annotation
messages: Membrane

230844:LOC102925108
gene id: 230844:LOC102925108
uniprot id: A0A6I9MAS1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

230844:Smc3
gene id: 230844:Smc3
uniprot id: A0A6I9MJC0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SMC family. SMC3 subfamily.
messages: Central component of cohesin, a complex required for chromosome cohesion during the cell cycle. The cohesin complex may form a large proteinaceous ring within which sister chromatids can be trapped. At anaphase, the complex is cleaved and dissociates from chromatin, allowing sister chromatids to segregate. Cohesion is coupled to DNA replication and is involved in DNA repair. The cohesin complex also plays an important role in spindle pole assembly during mitosis and in chromosomes movement.
messages: Nucleus
messages: centromere

230844:Slc25a1
gene id: 230844:Slc25a1
uniprot id: A0A6I9LR65
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

230844:Ptp4a2
gene id: 230844:Ptp4a2
uniprot id: A0A6I9M189
names: Subcellular Location Annotation
messages: Early endosome
messages: Endosome

230844:Ap4s1
gene id: 230844:Ap4s1
uniprot id: A0A6I9L9I6
names: Similarity
messages: Belongs to the adaptor complexes small subunit family.

230844:Enpp3
gene id: 230844:Enpp3
uniprot id: A0A6I9LY20
names: Subcellular Location Annotation
messages: Secreted

230844:Slc2a5
gene id: 230844:Slc2a5
uniprot id: A0A6J0D4G7
names: Similarity
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Cell membrane
messages: Membrane
messages: sarcolemma

230844:Asic4
gene id: 230844:Asic4
uniprot id: A0A6I9L310
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family.
messages: Membrane

230844:Col4a6
gene id: 230844:Col4a6
uniprot id: A0A6I9KSH9
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Type IV collagen is the major structural component of glomerular basement membranes (GBM), forming a 'chicken-wire' meshwork together with laminins, proteoglycans and entactin/nidogen.
messages: basement membrane

230844:C5H7orf25
gene id: 230844:C5H7orf25
uniprot id: A0A6J0DMH0
names: Similarity
messages: Belongs to the UPF0415 family.

230844:Fas
gene id: 230844:Fas
uniprot id: A0A6I9LJQ6
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane raft

230844:Nfib
gene id: 230844:Nfib
uniprot id: A0A6I9L2V9
uniprot id: A0A6I9LB20
uniprot id: A0A6I9LER8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CTF/NF-I family.
messages: Binds DNA as a homodimer.
messages: Nucleus
messages: Recognizes and binds the palindromic sequence 5'-TTGGCNNNNNGCCAA-3' present in viral and cellular promoters and in the origin of replication of adenovirus type 2. These proteins are individually capable of activating transcription and replication.

230844:Csta
gene id: 230844:Csta
uniprot id: A0A6I9LAG0
names: Similarity
messages: Belongs to the cystatin family.

230844:Trim50
gene id: 230844:Trim50
uniprot id: A0A6I9L174
names: Subcellular Location Annotation
messages: Cytoplasm

230844:Pih1d2
gene id: 230844:Pih1d2
uniprot id: A0A6I9L3G8
names: Similarity
messages: Belongs to the PIH1 family.

230844:Kcnj9
gene id: 230844:Kcnj9
uniprot id: A0A6J0EBI7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family.
messages: Membrane

230844:Ssr4
gene id: 230844:Ssr4
uniprot id: A0A6I9M901
uniprot id: A0A6J0CGC9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP-delta family.
messages: Endoplasmic reticulum membrane
messages: Heterotetramer of TRAP-alpha, TRAP-beta, TRAP-delta and TRAP-gamma.
messages: Membrane
messages: TRAP proteins are part of a complex whose function is to bind calcium to the ER membrane and thereby regulate the retention of ER resident proteins.

230844:Vps41
gene id: 230844:Vps41
uniprot id: A0A6I9LVQ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VPS41 family.
messages: Early endosome membrane
messages: Endosome membrane
messages: Late endosome membrane
messages: Lysosome membrane
messages: Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport pathways.
messages: Vesicle
messages: clathrin-coated vesicle
messages: trans-Golgi network

230844:LOC102921519
gene id: 230844:LOC102921519
uniprot id: A0A6I9MKC8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Adcy7
gene id: 230844:Adcy7
uniprot id: A0A6J0E1Q6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
messages: Binds 2 magnesium ions per subunit. Is also active with manganese (in vitro).
messages: Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.
messages: Membrane

230844:Atp6v1g2
gene id: 230844:Atp6v1g2
uniprot id: A0A6I9MAB6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the V-ATPase G subunit family.
messages: Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment.
messages: V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex.

230844:Phka1
gene id: 230844:Phka1
uniprot id: A0A6I9M4P6
uniprot id: A0A6I9MFV1
uniprot id: A0A6J0CPD7
uniprot id: A0A6J0CRJ4
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Although the final Cys may be farnesylated, the terminal tripeptide is probably not removed, and the C-terminus is not methylated.
messages: Belongs to the phosphorylase b kinase regulatory chain family.
messages: Cell membrane
messages: Hexadecamer of 4 heterotetramers, each composed of alpha, beta, gamma, and delta subunits. Alpha (PHKA1 or PHKA2) and beta (PHKB) are regulatory subunits, gamma (PHKG1 or PHKG2) is the catalytic subunit, and delta is calmodulin.
messages: Membrane
messages: Phosphorylase b kinase catalyzes the phosphorylation of serine in certain substrates, including troponin I. The alpha chain may bind calmodulin.

230844:Ipmk
gene id: 230844:Ipmk
uniprot id: A0A6I9LHY5
names: Similarity
messages: Belongs to the inositol phosphokinase (IPK) family.

230844:Ccl22
gene id: 230844:Ccl22
uniprot id: A0A6I9LZY8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the intercrine beta (chemokine CC) family.
messages: Secreted

230844:Cxcr6
gene id: 230844:Cxcr6
uniprot id: A0A6J0E864
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

230844:Aldh16a1
gene id: 230844:Aldh16a1
uniprot id: A0A6I9LXE8
names: Similarity
names: Subunit
messages: Belongs to the aldehyde dehydrogenase family.
messages: Interacts with SPG21.

230844:Arl14
gene id: 230844:Arl14
uniprot id: A0A6I9L7C0
names: Similarity
messages: Belongs to the small GTPase superfamily. Arf family.

230844:Map2k5
gene id: 230844:Map2k5
uniprot id: A0A6I9L4I1
uniprot id: A0A6J0DVB8
uniprot id: A0A6J0DW68
names: Similarity
messages: Belongs to the protein kinase superfamily.

230844:LOC102904443
gene id: 230844:LOC102904443
uniprot id: A0A6I9LAQ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GST superfamily. Mu family.
messages: Cytoplasm

230844:Znf394
gene id: 230844:Znf394
uniprot id: A0A6I9LPC1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the krueppel C2H2-type zinc-finger protein family.
messages: Nucleus

230844:Purb
gene id: 230844:Purb
uniprot id: A0A6J0D143
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PUR DNA-binding protein family.
messages: Nucleus

230844:Ciao2a
gene id: 230844:Ciao2a
uniprot id: A0A6I9LIM9
names: Similarity
messages: Belongs to the MIP18 family.

230844:LOC102924933
gene id: 230844:LOC102924933
uniprot id: A0A6I9M5X4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Homer3
gene id: 230844:Homer3
uniprot id: A0A6I9M456
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Homer family.
messages: Cytoplasm
messages: Postsynaptic density
messages: Synapse

230844:Atad2b
gene id: 230844:Atad2b
uniprot id: A0A6I9LEM6
uniprot id: A0A6J0DKU9
uniprot id: A0A6J0DRI7
names: Similarity
messages: Belongs to the AAA ATPase family.

230844:Pan2
gene id: 230844:Pan2
uniprot id: A0A6I9LS34
uniprot id: A0A6I9M091
names: Activity Regulation
names: Caution
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase C19 family. PAN2 subfamily.
messages: Binds 2 metal cations per subunit in the catalytic exonuclease domain.
messages: Catalytic subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in general and miRNA-mediated mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein (PABP). PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent mRNA decaping and subsequent 5'-3' exonucleolytic degradation by XRN1. Also acts as an important regulator of the HIF1A-mediated hypoxic response. Required for HIF1A mRNA stability independent of poly(A) tail length regulation.
messages: Contains a pseudo-UCH domain. This ubiquitin C-terminal hydrolase (UCH)-like or ubiquitin specific protease (USP)-like domain is predicted to be catalytically inactive because it lacks the active site catalytic triad characteristic of thiol proteases, with residues at the equivalent structural positions that are incompatible with catalysis, and it cannot bind ubiquitin. It functions as a structural scaffold for intra- and intermolecular interactions in the complex.
messages: Forms a heterotrimer with an asymmetric homodimer of the regulatory subunit PAN3 to form the poly(A)-nuclease (PAN) deadenylation complex. Interacts with ZFP36.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus
messages: P-body
messages: Positively regulated by the regulatory subunit PAN3.
messages: The linker, or PAN3 interaction domain (PID), between the WD40 repeats and the pseudo-UCH domain mediates interaction with PAN3.

230844:Ppm1n
gene id: 230844:Ppm1n
uniprot id: A0A6J0CIW9
names: Similarity
messages: Belongs to the PP2C family.

230844:Slc6a13
gene id: 230844:Slc6a13
uniprot id: A0A6I9M8Q4
names: Similarity
names: Subcellular Location Annotation
messages: Basolateral cell membrane
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. SLC6A13 subfamily.
messages: Cell membrane
messages: Lateral cell membrane
messages: Membrane

230844:LOC107400013
gene id: 230844:LOC107400013
uniprot id: A0A6J0CRB0
names: Subcellular Location Annotation
messages: Membrane

230844:Taf1a
gene id: 230844:Taf1a
uniprot id: A0A6J0EA81
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Component of the transcription factor SL1/TIF-IB complex, composed of TBP and at least TAF1A, TAF1B, TAF1C and TAF1D. In the complex interacts directly with TBP, TAF1A and TAF1B. Interaction of the SL1/TIF-IB subunits with TBP excludes interaction of TBP with the transcription factor IID (TFIID) subunits.
messages: Component of the transcription factor SL1/TIF-IB complex, which is involved in the assembly of the PIC (pre-initiation complex) during RNA polymerase I-dependent transcription. The rate of PIC formation probably is primarily dependent on the rate of association of SL1/TIF-IB with the rDNA promoter. SL1/TIF-IB is involved in stabilization of nucleolar transcription factor 1/UBTF on rDNA. Formation of SL1/TIF-IB excludes the association of TBP with TFIID subunits.
messages: Nucleus

230844:Slc50a1
gene id: 230844:Slc50a1
uniprot id: A0A6I9LFI4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SWEET sugar transporter family.
messages: Golgi apparatus membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mediates sugar transport across membranes.
messages: Membrane

230844:LOC102910854
gene id: 230844:LOC102910854
uniprot id: A0A6I9LF66
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

230844:Gstz1
gene id: 230844:Gstz1
uniprot id: A0A6I9LZ40
uniprot id: A0A6I9M4T6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GST superfamily. Zeta family.
messages: Cytoplasm

230844:Xpnpep1
gene id: 230844:Xpnpep1
uniprot id: A0A6I9LXP6
uniprot id: A0A6J0CFI4
uniprot id: A0A6J0CFX4
names: Similarity
messages: Belongs to the peptidase M24B family.

230844:Litafd
gene id: 230844:Litafd
uniprot id: A0A6I9M8B5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDIP1/LITAF family.
messages: Lysosome membrane

230844:Smad5
gene id: 230844:Smad5
uniprot id: A0A6I9L476
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dwarfin/SMAD family.
messages: Cytoplasm
messages: Nucleus

230844:Asb13
gene id: 230844:Asb13
uniprot id: A0A6J0E6J3
names: Similarity
messages: Belongs to the ankyrin SOCS box (ASB) family.

230844:Kif15
gene id: 230844:Kif15
uniprot id: A0A6I9M5T2
uniprot id: A0A6J0E850
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. KIN-12 subfamily.
messages: spindle

230844:Pdlim3
gene id: 230844:Pdlim3
uniprot id: A0A6I9KU81
uniprot id: A0A6I9L374
names: Subcellular Location Annotation
messages: Z line

230844:Tle3
gene id: 230844:Tle3
uniprot id: A0A6J0DT22
uniprot id: A0A6J0DT31
uniprot id: A0A6J0DUG7
uniprot id: A0A6J0DUH7
uniprot id: A0A6J0DUI9
uniprot id: A0A6J0DVW0
uniprot id: A0A6J0DVX6
uniprot id: A0A6J0DVY2
uniprot id: A0A6J0DWU2
uniprot id: A0A6J0E1C3
uniprot id: A0A6J0E1D2
uniprot id: A0A6J0E1E8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat Groucho/TLE family.
messages: Nucleus

230844:Pik3c2b
gene id: 230844:Pik3c2b
uniprot id: A0A6I9M634
uniprot id: A0A6J0CIA9
names: Similarity
messages: Belongs to the PI3/PI4-kinase family. Type III PI4K subfamily.

230844:Pde1a
gene id: 230844:Pde1a
uniprot id: A0A6J0CSS1
uniprot id: A0A6J0CTZ2
uniprot id: A0A6J0CX15
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family. PDE1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

230844:Mmd2
gene id: 230844:Mmd2
uniprot id: A0A6I9MEI9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ADIPOR family.
messages: Membrane

230844:Spata31d1
gene id: 230844:Spata31d1
uniprot id: A0A6I9LME4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPATA31 family.
messages: Membrane

230844:Hpx
gene id: 230844:Hpx
uniprot id: A0A6I9MCR0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the hemopexin family.
messages: Binds heme and transports it to the liver for breakdown and iron recovery, after which the free hemopexin returns to the circulation.
messages: Secreted

230844:LOC102927205
gene id: 230844:LOC102927205
uniprot id: A0A6I9M6I6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:LOC102917181
gene id: 230844:LOC102917181
uniprot id: A0A6I9LXF7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Mpdu1
gene id: 230844:Mpdu1
uniprot id: A0A6I9L936
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MPDU1 (TC 2.A.43.3) family.
messages: Membrane
messages: Required for normal utilization of mannose-dolichol phosphate (Dol-P-Man) in the synthesis of N-linked and O-linked oligosaccharides and GPI anchors.

230844:P2ry12
gene id: 230844:P2ry12
uniprot id: A0A6I9MD93
names: Subcellular Location Annotation
messages: Membrane

230844:Gabbr1
gene id: 230844:Gabbr1
uniprot id: A0A6J0CWF4
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 3 family. GABA-B receptor subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

230844:LOC102912484
gene id: 230844:LOC102912484
uniprot id: A0A6J0E1E2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.
messages: cytoskeleton

230844:Gprc5d
gene id: 230844:Gprc5d
uniprot id: A0A6I9L4Q8
uniprot id: A0A6I9LC50
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

230844:Paqr6
gene id: 230844:Paqr6
uniprot id: A0A6I9LFN2
uniprot id: A0A6J0D6J6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ADIPOR family.
messages: Membrane

230844:Trmt2a
gene id: 230844:Trmt2a
uniprot id: A0A6I9MFR9
names: Caution
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

230844:Itih1
gene id: 230844:Itih1
uniprot id: A0A6I9LM25
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ITIH family.
messages: Secreted

230844:Ahsa1
gene id: 230844:Ahsa1
uniprot id: A0A6I9M4T9
names: Similarity
messages: Belongs to the AHA1 family.

230844:Adamts5
gene id: 230844:Adamts5
uniprot id: A0A6I9M079
names: Caution
names: Cofactor
names: Subcellular Location Annotation
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

230844:Ywhah
gene id: 230844:Ywhah
uniprot id: A0A6I9L7V4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 14-3-3 family.
messages: Cytoplasm

230844:LOC102926390
gene id: 230844:LOC102926390
uniprot id: A0A6I9MJT7
names: Cofactor
names: PTM
names: Similarity
messages: Belongs to the copper/topaquinone oxidase family.
messages: Contains 1 topaquinone per subunit.
messages: Topaquinone (TPQ) is generated by copper-dependent autoxidation of a specific tyrosyl residue.

230844:Bpgm
gene id: 230844:Bpgm
uniprot id: A0A6I9LU37
names: Similarity
messages: Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.

230844:Lhx6
gene id: 230844:Lhx6
uniprot id: A0A6I9MAF1
uniprot id: A0A6I9MEH8
uniprot id: A0A6J0CMU3
uniprot id: A0A6J0CRN3
names: Subcellular Location Annotation
messages: Nucleus

230844:Arl8b
gene id: 230844:Arl8b
uniprot id: A0A6I9LM02
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Arf family.
messages: Endosome membrane
messages: Late endosome membrane
messages: Lysosome membrane
messages: axon
messages: spindle

230844:Prox2
gene id: 230844:Prox2
uniprot id: A0A6I9LHD2
names: Subcellular Location Annotation
messages: Nucleus

230844:Kcna1
gene id: 230844:Kcna1
uniprot id: A0A6I9LPR2
names: Subcellular Location Annotation
messages: Membrane

230844:LOC102920127
gene id: 230844:LOC102920127
uniprot id: A0A6I9LYT9
names: Similarity
messages: Belongs to the CLCR family.

230844:Pex16
gene id: 230844:Pex16
uniprot id: A0A6I9MJD4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peroxin-16 family.
messages: Peroxisome membrane

230844:Spring1
gene id: 230844:Spring1
uniprot id: A0A6I9KTG4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPRING family.
messages: Golgi apparatus membrane
messages: Membrane

230844:Afg3l2
gene id: 230844:Afg3l2
uniprot id: A0A6I9KYM1
names: Similarity
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the N-terminal section; belongs to the AAA ATPase family.

230844:LOC102904038
gene id: 230844:LOC102904038
uniprot id: A0A6J0DT07
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SMAGP family.
messages: Cell membrane
messages: Cytoplasmic vesicle membrane
messages: Membrane

230844:Asic1
gene id: 230844:Asic1
uniprot id: A0A6I9L0B1
names: Subcellular Location Annotation
messages: Membrane

230844:LOC107402387
gene id: 230844:LOC107402387
uniprot id: A0A6J0DYA3
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL39 family.

230844:Rab9a
gene id: 230844:Rab9a
uniprot id: A0A6I9KXZ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Membrane
messages: phagosome membrane

230844:Tlcd5
gene id: 230844:Tlcd5
uniprot id: A0A6I9LLJ5
uniprot id: A0A6J0DJU4
names: Subcellular Location Annotation
messages: Membrane

230844:P2rx4
gene id: 230844:P2rx4
uniprot id: A0A6I9L009
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the P2X receptor family.
messages: Functional P2XRs are organized as homomeric and heteromeric trimers.
messages: Membrane
messages: Receptor for ATP that acts as a ligand-gated ion channel.

230844:LOC102922071
gene id: 230844:LOC102922071
uniprot id: A0A6I9LRV4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

230844:LOC102925558
gene id: 230844:LOC102925558
uniprot id: A0A6I9LBX6
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. UDP-glucuronic acid decarboxylase subfamily.

230844:Tet2
gene id: 230844:Tet2
uniprot id: A0A6I9KZ51
uniprot id: A0A6J0CYB6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TET family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Chromosome
messages: Dioxygenase that catalyzes the conversion of the modified genomic base 5-methylcytosine (5mC) into 5-hydroxymethylcytosine (5hmC) and plays a key role in epigenetic chromatin reprogramming during embryonic development.
messages: The zinc ions have a structural role.

230844:Dus3l
gene id: 230844:Dus3l
uniprot id: A0A6I9LNI6
names: Similarity
messages: Belongs to the dus family. Dus3 subfamily.

230844:Chd1l
gene id: 230844:Chd1l
uniprot id: A0A6J0DUZ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNF2/RAD54 helicase family.
messages: Nucleus

230844:LOC102924617
gene id: 230844:LOC102924617
uniprot id: A0A6I9LHV0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:LOC102919029
gene id: 230844:LOC102919029
uniprot id: A0A6I9LTG7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the intercrine beta (chemokine CC) family.
messages: Secreted

230844:Ndufaf1
gene id: 230844:Ndufaf1
uniprot id: A0A6J0E9I2
names: Function
names: Similarity
messages: As part of the MCIA complex, involved in the assembly of the mitochondrial complex I.
messages: Belongs to the CIA30 family.

230844:LOC102924379
gene id: 230844:LOC102924379
uniprot id: A0A6I9M949
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:LOC102921963
gene id: 230844:LOC102921963
uniprot id: A0A6I9LQ48
names: Similarity
messages: Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.

230844:Eps8l3
gene id: 230844:Eps8l3
uniprot id: A0A6J0DFJ5
names: Similarity
messages: Belongs to the EPS8 family.

230844:Spc24
gene id: 230844:Spc24
uniprot id: A0A6I9LGB3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity.
messages: Belongs to the SPC24 family.
messages: Component of the NDC80 complex.
messages: Nucleus
messages: kinetochore

230844:Ern2
gene id: 230844:Ern2
uniprot id: A0A6I9LAV0
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

230844:LOC102905991
gene id: 230844:LOC102905991
uniprot id: A0A6I9MK01
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Cacna2d3
gene id: 230844:Cacna2d3
uniprot id: A0A6I9LCZ4
uniprot id: A0A6I9LSF8
names: Similarity
messages: Belongs to the calcium channel subunit alpha-2/delta family.

230844:Hoxc4
gene id: 230844:Hoxc4
uniprot id: A0A6I9LNV3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Antp homeobox family.
messages: Nucleus

230844:Tmed1
gene id: 230844:Tmed1
uniprot id: A0A6I9LZC6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EMP24/GP25L family.
messages: Endoplasmic reticulum membrane
messages: Endoplasmic reticulum-Golgi intermediate compartment membrane
messages: Membrane
messages: cis-Golgi network membrane

230844:Cacna1g
gene id: 230844:Cacna1g
uniprot id: A0A6I9KVQ9
uniprot id: A0A6I9KVR5
uniprot id: A0A6I9KW17
uniprot id: A0A6I9KW21
uniprot id: A0A6I9L2B3
uniprot id: A0A6I9L2B8
uniprot id: A0A6I9L2R3
uniprot id: A0A6I9L2S5
uniprot id: A0A6J0ED47
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family.
messages: Membrane
messages: Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. This channel gives rise to T-type calcium currents. T-type calcium channels belong to the "low-voltage activated (LVA)" group and are strongly blocked by nickel and mibefradil. A particularity of this type of channels is an opening at quite negative potentials, and a voltage-dependent inactivation. T-type channels serve pacemaking functions in both central neurons and cardiac nodal cells and support calcium signaling in secretory cells and vascular smooth muscle. They may also be involved in the modulation of firing patterns of neurons which is important for information processing as well as in cell growth processes.

230844:Atrnl1
gene id: 230844:Atrnl1
uniprot id: A0A6I9LK95
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

230844:Slc7a10
gene id: 230844:Slc7a10
uniprot id: A0A6I9LU66
names: Subcellular Location Annotation
messages: Membrane

230844:Tmem255a
gene id: 230844:Tmem255a
uniprot id: A0A6I9LEW8
uniprot id: A0A6I9LM65
uniprot id: A0A6I9LSM0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM255 family.
messages: Membrane

230844:Rbpj
gene id: 230844:Rbpj
uniprot id: A0A6J0CNN4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Su(H) family.
messages: Nucleus

230844:Prph
gene id: 230844:Prph
uniprot id: A0A6I9L0G9
uniprot id: A0A6I9L7R4
uniprot id: A0A6I9L7S7
uniprot id: A0A6I9LBB2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the intermediate filament family.
messages: axon

230844:Fam98c
gene id: 230844:Fam98c
uniprot id: A0A6I9LTS0
names: Similarity
messages: Belongs to the FAM98 family.

230844:LOC102914527
gene id: 230844:LOC102914527
uniprot id: A0A6I9MEY3
names: Similarity
messages: Belongs to the CTAG/PCC1 family.

230844:Yy2
gene id: 230844:Yy2
uniprot id: A0A6J0D224
names: Similarity
messages: Belongs to the YY transcription factor family.

230844:Il17d
gene id: 230844:Il17d
uniprot id: A0A6I9M6R7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IL-17 family.
messages: Secreted

230844:S100b
gene id: 230844:S100b
uniprot id: A0A6J0CIT5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the S-100 family.
messages: Cytoplasm
messages: Nucleus
messages: Secreted

230844:Dguok
gene id: 230844:Dguok
uniprot id: A0A6I9MCP3
uniprot id: A0A6J0CLS9
names: Similarity
messages: Belongs to the DCK/DGK family.

230844:Asb8
gene id: 230844:Asb8
uniprot id: A0A6I9LB78
names: Function
names: Similarity
messages: Belongs to the ankyrin SOCS box (ASB) family.
messages: May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.

230844:Acsm4
gene id: 230844:Acsm4
uniprot id: A0A6I9LKU0
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

230844:LOC102909678
gene id: 230844:LOC102909678
uniprot id: A0A6J0D778
names: Similarity
messages: Belongs to the LCE family.

230844:Taf6l
gene id: 230844:Taf6l
uniprot id: A0A6I9MEA1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAF6 family.
messages: Nucleus

230844:Iah1
gene id: 230844:Iah1
uniprot id: A0A6I9LCC1
uniprot id: A0A6J0D7B7
names: Function
names: Similarity
messages: Belongs to the 'GDSL' lipolytic enzyme family. IAH1 subfamily.
messages: Probable lipase.

230844:Aqp8
gene id: 230844:Aqp8
uniprot id: A0A6I9LKR1
uniprot id: A0A6J0DF37
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

230844:Nupr1
gene id: 230844:Nupr1
uniprot id: A0A6I9LKT4
names: Similarity
messages: Belongs to the NUPR family.

230844:Adora3
gene id: 230844:Adora3
uniprot id: A0A6I9LXF8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for adenosine. The activity of this receptor is mediated by G proteins which inhibit adenylyl cyclase.

230844:Pspn
gene id: 230844:Pspn
uniprot id: A0A6I9LPT1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TGF-beta family. GDNF subfamily.
messages: Secreted

230844:LOC102922314
gene id: 230844:LOC102922314
uniprot id: A0A6I9L2M3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STK11IP family.
messages: Cytoplasm

230844:LOC102906932
gene id: 230844:LOC102906932
uniprot id: A0A6J0DQR3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ITPRIP family.
messages: Membrane

230844:Fabp1
gene id: 230844:Fabp1
uniprot id: A0A6I9M0L4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.
messages: Binds free fatty acids and their coenzyme A derivatives, bilirubin, and some other small molecules in the cytoplasm. May be involved in intracellular lipid transport.
messages: Cytoplasm
messages: Forms a beta-barrel structure that accommodates hydrophobic ligands in its interior.

230844:Anxa13
gene id: 230844:Anxa13
uniprot id: A0A6I9M5I1
names: Domain
names: Similarity
messages: A pair of annexin repeats may form one binding site for calcium and phospholipid.
messages: Belongs to the annexin family.

230844:Niban2
gene id: 230844:Niban2
uniprot id: A0A6I9M928
names: Similarity
messages: Belongs to the Niban family.

230844:LOC102923645
gene id: 230844:LOC102923645
uniprot id: A0A6I9LUU1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IL-3 family.
messages: Secreted

230844:Tmeff1
gene id: 230844:Tmeff1
uniprot id: A0A6I9KZ30
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

230844:Lrrc8c
gene id: 230844:Lrrc8c
uniprot id: A0A6J0DZ81
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LRRC8 family.
messages: Cell membrane
messages: Membrane

230844:Rpl31
gene id: 230844:Rpl31
uniprot id: A0A6I9LPU9
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eL31 family.
messages: Component of the large ribosomal subunit.

230844:LOC102915620
gene id: 230844:LOC102915620
uniprot id: A0A6I9M159
names: Similarity
messages: Belongs to the cytochrome P450 family.

230844:Tubb6
gene id: 230844:Tubb6
uniprot id: A0A6I9KS07
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.
messages: cytoskeleton

230844:Atp10a
gene id: 230844:Atp10a
uniprot id: A0A6I9LX12
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.
messages: Membrane

230844:Pou5f2
gene id: 230844:Pou5f2
uniprot id: A0A6I9LXP1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the POU transcription factor family.
messages: Nucleus

230844:LOC102907361
gene id: 230844:LOC102907361
uniprot id: A0A6J0E1C6
names: Similarity
messages: Belongs to the DEF8 family.

230844:Ascc3
gene id: 230844:Ascc3
uniprot id: A0A6I9LX35
names: Similarity
messages: Belongs to the helicase family.

230844:LOC102914791
gene id: 230844:LOC102914791
uniprot id: A0A6I9M920
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the somatotropin/prolactin family.
messages: Secreted

230844:LOC107399681
gene id: 230844:LOC107399681
uniprot id: A0A6J0CN26
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Lzts2
gene id: 230844:Lzts2
uniprot id: A0A6J0E9C7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LZTS2 family.
messages: Cytoplasm
messages: Interacts with KATNB1. Also interacts with CTNNB1, gamma-tubulin and KIF23.
messages: Negative regulator of katanin-mediated microtubule severing and release from the centrosome. Required for central spindle formation and the completion of cytokinesis. May negatively regulate axonal outgrowth by preventing the formation of microtubule bundles that are necessary for transport within the elongating axon. Negative regulator of the Wnt signaling pathway. Represses beta-catenin-mediated transcriptional activation by promoting the nuclear exclusion of beta-catenin.
messages: centrosome

230844:Vps25
gene id: 230844:Vps25
uniprot id: A0A6I9MCD8
names: Similarity
messages: Belongs to the VPS25 family.

230844:Kcnt1
gene id: 230844:Kcnt1
uniprot id: A0A6I9LC21
uniprot id: A0A6I9LL45
uniprot id: A0A6I9LR86
uniprot id: A0A6J0DGN7
uniprot id: A0A6J0DJ18
uniprot id: A0A6J0DJ38
uniprot id: A0A6J0DJB8
uniprot id: A0A6J0DJC3
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

230844:Slc25a38
gene id: 230844:Slc25a38
uniprot id: A0A6I9MPZ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family. SLC25A38 subfamily.
messages: Membrane
messages: Mitochondrial glycine transporter that imports glycine into the mitochondrial matrix. Plays an important role in providing glycine for the first enzymatic step in heme biosynthesis, the condensation of glycine with succinyl-CoA to produce 5-aminolevulinate (ALA) in the miochondrial matrix. Required during erythropoiesis.
messages: Mitochondrion inner membrane
messages: Plays a role as pro-apoptotic protein that induces caspase-dependent apoptosis.

230844:Ppp2r5b
gene id: 230844:Ppp2r5b
uniprot id: A0A6I9LD75
names: Function
names: Similarity
messages: Belongs to the phosphatase 2A regulatory subunit B56 family.
messages: The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment.

230844:Stc1
gene id: 230844:Stc1
uniprot id: A0A6I9LXD9
names: Similarity
names: Subunit
messages: Belongs to the stanniocalcin family.
messages: Homodimer; disulfide-linked.

230844:LOC102924455
gene id: 230844:LOC102924455
uniprot id: A0A6I9LH08
uniprot id: A0A6I9LPD0
uniprot id: A0A6I9LQJ0
uniprot id: A0A6J0DPM0
names: Similarity
messages: Belongs to the RGS7BP/RGS9BP family.

230844:Slc6a3
gene id: 230844:Slc6a3
uniprot id: A0A6I9M5M3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. SLC6A3 subfamily.
messages: Cell membrane
messages: Membrane
messages: axon
messages: neuron projection

230844:Ehd1
gene id: 230844:Ehd1
uniprot id: A0A6I9LBG4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Endosome membrane
messages: Membrane

230844:Stag3
gene id: 230844:Stag3
uniprot id: A0A6I9L108
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SCC3 family.
messages: Chromosome
messages: Component of cohesin complex, a complex required for the cohesion of sister chromatids after DNA replication. The cohesin complex apparently forms a large proteinaceous ring within which sister chromatids can be trapped. At anaphase, the complex is cleaved and dissociates from chromatin, allowing sister chromatids to segregate.
messages: Nucleus
messages: Part of the cohesin complex which is composed of a heterodimer between a SMC1 protein (SMC1A or SMC1B) and SMC3, which are attached via their hinge domain, and RAD21 which link them at their heads, and one STAG protein.
messages: centromere

230844:Ackr1
gene id: 230844:Ackr1
uniprot id: A0A6I9M6I8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Atypical chemokine receptor that controls chemokine levels and localization via high-affinity chemokine binding that is uncoupled from classic ligand-driven signal transduction cascades, resulting instead in chemokine sequestration, degradation, or transcytosis. Also known as interceptor (internalizing receptor) or chemokine-scavenging receptor or chemokine decoy receptor. Has a promiscuous chemokine-binding profile, interacting with inflammatory chemokines of both the CXC and the CC subfamilies but not with homeostatic chemokines. Acts as a receptor for chemokines including CCL2, CCL5, CCL7, CCL11, CCL13, CCL14, CCL17, CXCL5, CXCL6, IL8/CXCL8, CXCL11, GRO, RANTES, MCP-1 and TARC. May regulate chemokine bioavailability and, consequently, leukocyte recruitment through two distinct mechanisms: when expressed in endothelial cells, it sustains the abluminal to luminal transcytosis of tissue-derived chemokines and their subsequent presentation to circulating leukocytes; when expressed in erythrocytes, serves as blood reservoir of cognate chemokines but also as a chemokine sink, buffering potential surges in plasma chemokine levels.
messages: Belongs to the G-protein coupled receptor 1 family. Atypical chemokine receptor subfamily.
messages: Early endosome
messages: Membrane
messages: Recycling endosome

230844:Tmem237
gene id: 230844:Tmem237
uniprot id: A0A6I9L926
uniprot id: A0A6J0D3A2
uniprot id: A0A6J0D7K3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM237 family.
messages: Component of the transition zone in primary cilia. Required for ciliogenesis.
messages: Membrane
messages: cilium

230844:Slc17a2
gene id: 230844:Slc17a2
uniprot id: A0A6I9LZD7
uniprot id: A0A6I9MAC7
names: Subcellular Location Annotation
messages: Membrane

230844:Nefl
gene id: 230844:Nefl
uniprot id: A0A6I9LX37
names: Similarity
messages: Belongs to the intermediate filament family.

230844:Ttc9c
gene id: 230844:Ttc9c
uniprot id: A0A6I9MA88
names: Similarity
messages: Belongs to the TTC9 family.

230844:Abr
gene id: 230844:Abr
uniprot id: A0A6I9L5C3
uniprot id: A0A6I9LDY0
uniprot id: A0A6I9LI11
names: Subcellular Location Annotation
messages: Synapse
messages: axon
messages: dendritic spine

230844:Pcyt1a
gene id: 230844:Pcyt1a
uniprot id: A0A6I9L0H2
names: Function
names: Similarity
messages: Belongs to the cytidylyltransferase family.
messages: Catalyzes the key rate-limiting step in the CDP-choline pathway for phosphatidylcholine biosynthesis.

230844:Kdm4c
gene id: 230844:Kdm4c
uniprot id: A0A6J0DKC7
uniprot id: A0A6J0DKN0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the JHDM3 histone demethylase family.
messages: Nucleus

230844:Tprg1l
gene id: 230844:Tprg1l
uniprot id: A0A6I9LS55
names: Similarity
messages: Belongs to the TPRG1 family.

230844:Tbx19
gene id: 230844:Tbx19
uniprot id: A0A6I9M295
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

230844:Ublcp1
gene id: 230844:Ublcp1
uniprot id: A0A6I9L4Z2
names: Subcellular Location Annotation
messages: Nucleus

230844:LOC102919125
gene id: 230844:LOC102919125
uniprot id: A0A6I9M3R7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:C7H11orf87
gene id: 230844:C7H11orf87
uniprot id: A0A6J0CGC5
names: Subcellular Location Annotation
messages: Membrane

230844:Fitm1
gene id: 230844:Fitm1
uniprot id: A0A6I9LQX2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FIT family. FIT1 subfamily.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Plays an important role in the formation of lipid droplets (LDs), which are storage organelles at the center of lipid and energy homeostasis. Directly binds to diacylglycerol (DAGs) and triacylglycerol.

230844:Ctdp1
gene id: 230844:Ctdp1
uniprot id: A0A6I9KZB8
uniprot id: A0A6J0CYA2
uniprot id: A0A6J0CZY1
names: Function
names: Subcellular Location Annotation
messages: Nucleus
messages: This promotes the activity of RNA polymerase II.

230844:Pgm5
gene id: 230844:Pgm5
uniprot id: A0A6I9LIG9
names: Similarity
messages: Belongs to the phosphohexose mutase family.

230844:Kcnk6
gene id: 230844:Kcnk6
uniprot id: A0A6I9LE09
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
messages: Membrane

230844:LOC102905248
gene id: 230844:LOC102905248
uniprot id: A0A6I9M7D1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Pisd
gene id: 230844:Pisd
uniprot id: A0A6I9KXG5
uniprot id: A0A6I9L4P7
uniprot id: A0A6J0CVH3
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Eukaryotic type I sub-subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer). Plays a central role in phospholipid metabolism and in the interorganelle trafficking of phosphatidylserine.
messages: Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The autoendoproteolytic cleavage occurs by a canonical serine protease mechanism, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain. During this reaction, the Ser that is part of the protease active site of the proenzyme becomes the pyruvoyl prosthetic group, which constitutes an essential element of the active site of the mature decarboxylase.
messages: Mitochondrion inner membrane

230844:Eif4a1
gene id: 230844:Eif4a1
uniprot id: A0A6I9KYG1
names: Domain
names: Function
names: Similarity
messages: Belongs to the DEAD box helicase family. eIF4A subfamily.
messages: RNA helicase.
messages: The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.

230844:Cacng1
gene id: 230844:Cacng1
uniprot id: A0A6I9KTI7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily.
messages: Component of a calcium channel complex consisting of a pore-forming alpha subunit (CACNA1S) and the ancillary subunits CACNB1 or CACNB2, CACNG1 and CACNA2D1. The channel complex contains alpha, beta, gamma and delta subunits in a 1:1:1:1 ratio, i.e. it contains either CACNB1 or CACNB2.
messages: Membrane
messages: Regulatory subunit of the voltage-gated calcium channel that gives rise to L-type calcium currents in skeletal muscle. Regulates channel inactivation kinetics.
messages: sarcolemma

230844:LOC102909160
gene id: 230844:LOC102909160
uniprot id: A0A6I9M4X9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Fbxo45
gene id: 230844:Fbxo45
uniprot id: A0A6I9L0W3
names: Similarity
messages: Belongs to the FBXO45/Fsn family.

230844:LOC102916747
gene id: 230844:LOC102916747
uniprot id: A0A6I9M5R7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PMG family.
messages: In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins.
messages: Interacts with hair keratins.

230844:Cnih2
gene id: 230844:Cnih2
uniprot id: A0A6I9LL78
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cornichon family.
messages: Membrane

230844:Myg1
gene id: 230844:Myg1
uniprot id: A0A6I9LMQ5
names: Similarity
messages: Belongs to the MYG1 family.

230844:Brf1
gene id: 230844:Brf1
uniprot id: A0A6I9LPZ8
uniprot id: A0A6I9M0B8
names: Similarity
messages: Belongs to the TFIIB family.

230844:LOC102912431
gene id: 230844:LOC102912431
uniprot id: A0A6I9LAZ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alpha/beta interferon family.
messages: Secreted

230844:Clptm1
gene id: 230844:Clptm1
uniprot id: A0A6I9MIU0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CLPTM1 family.
messages: Membrane

230844:Cpne9
gene id: 230844:Cpne9
uniprot id: A0A6I9MMY6
names: Similarity
messages: Belongs to the copine family.

230844:LOC102908992
gene id: 230844:LOC102908992
uniprot id: A0A6I9LZC3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Mycn
gene id: 230844:Mycn
uniprot id: A0A6I9LCA3
names: Subcellular Location Annotation
names: Subunit
messages: Efficient DNA binding requires dimerization with another bHLH protein.
messages: Nucleus

230844:Ddost
gene id: 230844:Ddost
uniprot id: A0A6I9LQZ8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DDOST 48 kDa subunit family.
messages: Component of the oligosaccharyltransferase (OST) complex.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER).

230844:Tns4
gene id: 230844:Tns4
uniprot id: A0A6I9L1Z7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PTEN phosphatase protein family.
messages: focal adhesion

230844:Coq5
gene id: 230844:Coq5
uniprot id: A0A6I9MBB9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Component of a multi-subunit COQ enzyme complex, composed of at least COQ3, COQ4, COQ5, COQ6, COQ7 and COQ9.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methyltransferase required for the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2).
messages: Mitochondrion inner membrane

230844:LOC102929018
gene id: 230844:LOC102929018
uniprot id: A0A6I9LHT4
names: Similarity
messages: Belongs to the globin family.

230844:LOC102910704
gene id: 230844:LOC102910704
uniprot id: A0A6I9M3P9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:LOC102916574
gene id: 230844:LOC102916574
uniprot id: A0A6I9MG68
names: Subcellular Location Annotation
messages: Secreted

230844:Inpp1
gene id: 230844:Inpp1
uniprot id: A0A6J0D2Q4
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

230844:Tpra1
gene id: 230844:Tpra1
uniprot id: A0A6I9MGQ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0359 family.
messages: Membrane

230844:LOC102926946
gene id: 230844:LOC102926946
uniprot id: A0A6I9M7V8
names: Similarity
messages: Belongs to the 'GDXG' lipolytic enzyme family.

230844:LOC102904527
gene id: 230844:LOC102904527
uniprot id: A0A6I9L247
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAF9 family. CENP-S/MHF1 subfamily.
messages: Belongs to the somatostatin family.
messages: Secreted

230844:Gja10
gene id: 230844:Gja10
uniprot id: A0A6I9LD90
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

230844:LOC102919522
gene id: 230844:LOC102919522
uniprot id: A0A6I9LUW6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

230844:Pgm3
gene id: 230844:Pgm3
uniprot id: A0A6J0DPE2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of GlcNAc-6-P into GlcNAc-1-P during the synthesis of uridine diphosphate/UDP-GlcNAc, a sugar nucleotide critical to multiple glycosylation pathways including protein N- and O-glycosylation.

230844:Serinc2
gene id: 230844:Serinc2
uniprot id: A0A6I9LA27
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TDE1 family.
messages: Membrane

230844:Lamc1
gene id: 230844:Lamc1
uniprot id: A0A6I9LNQ2
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: basement membrane

230844:LOC102925966
gene id: 230844:LOC102925966
uniprot id: A0A6I9MDZ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Lgr4
gene id: 230844:Lgr4
uniprot id: A0A6J0DIE6
names: Subcellular Location Annotation
messages: Membrane

230844:Ppfia1
gene id: 230844:Ppfia1
uniprot id: A0A6I9L6D0
uniprot id: A0A6J0D7R8
uniprot id: A0A6J0D7S8
uniprot id: A0A6J0D982
uniprot id: A0A6J0D9H5
uniprot id: A0A6J0DA04
names: Similarity
messages: Belongs to the liprin family. Liprin-alpha subfamily.

230844:Ypel5
gene id: 230844:Ypel5
uniprot id: A0A6I9MAZ2
names: Similarity
messages: Belongs to the yippee family.

230844:LOC102920582
gene id: 230844:LOC102920582
uniprot id: A0A6I9LWK7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

230844:Etf1
gene id: 230844:Etf1
uniprot id: A0A6I9L7K4
uniprot id: A0A6J0DAS9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic release factor 1 family.
messages: Cytoplasm

230844:Tspyl2
gene id: 230844:Tspyl2
uniprot id: A0A6I9MH44
names: Similarity
messages: Belongs to the nucleosome assembly protein (NAP) family.

230844:Rin3
gene id: 230844:Rin3
uniprot id: A0A6I9LV35
names: Similarity
messages: Belongs to the RIN (Ras interaction/interference) family.

230844:LOC102905333
gene id: 230844:LOC102905333
uniprot id: A0A6I9MFV8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Gramd1c
gene id: 230844:Gramd1c
uniprot id: A0A6I9LE89
uniprot id: A0A6J0D4T8
uniprot id: A0A6J0D5F2
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

230844:Miox
gene id: 230844:Miox
uniprot id: A0A6I9L407
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the myo-inositol oxygenase family.
messages: Binds 2 iron ions per subunit.
messages: Cytoplasm

230844:LOC102906507
gene id: 230844:LOC102906507
uniprot id: A0A6I9MPL9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Bcl2
gene id: 230844:Bcl2
uniprot id: A0A6I9MGI6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Bcl-2 family.
messages: Cytoplasm
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Mitochondrion outer membrane
messages: Nucleus membrane

230844:Nrp2
gene id: 230844:Nrp2
uniprot id: A0A6I9L909
uniprot id: A0A6I9LCP1
uniprot id: A0A6J0D374
names: Caution
names: Similarity
messages: Belongs to the neuropilin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

230844:Antxrl
gene id: 230844:Antxrl
uniprot id: A0A6I9L467
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATR family.
messages: Membrane

230844:LOC102920595
gene id: 230844:LOC102920595
uniprot id: A0A6J0D536
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

230844:LOC102909350
gene id: 230844:LOC102909350
uniprot id: A0A6I9ME63
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:LOC102916896
gene id: 230844:LOC102916896
uniprot id: A0A6I9M8B6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Chst10
gene id: 230844:Chst10
uniprot id: A0A6I9LAW5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 2 family.
messages: Golgi apparatus membrane
messages: Membrane

230844:LOC102915975
gene id: 230844:LOC102915975
uniprot id: A0A6I9M879
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Gstk1
gene id: 230844:Gstk1
uniprot id: A0A6I9MLH8
names: Similarity
messages: Belongs to the GST superfamily. Kappa family.

230844:Rpa3
gene id: 230844:Rpa3
uniprot id: A0A6I9M3H0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the replication factor A protein 3 family.
messages: Nucleus

230844:Tspan9
gene id: 230844:Tspan9
uniprot id: A0A6I9LPQ2
uniprot id: A0A6I9M035
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

230844:Phtf1
gene id: 230844:Phtf1
uniprot id: A0A6I9LQT5
uniprot id: A0A6J0DIL9
names: Subcellular Location Annotation
messages: Membrane

230844:Ndufb8
gene id: 230844:Ndufb8
uniprot id: A0A6I9LQ88
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFB8 subunit family.
messages: Complex I is composed of 45 different subunits.
messages: Mitochondrion inner membrane

230844:LOC102915432
gene id: 230844:LOC102915432
uniprot id: A0A6I9M6T0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the intercrine alpha (chemokine CxC) family.
messages: Secreted

230844:Tbc1d7
gene id: 230844:Tbc1d7
uniprot id: A0A6I9KXI8
names: Subcellular Location Annotation
messages: Cytoplasmic vesicle
messages: Vesicle

230844:Bdkrb1
gene id: 230844:Bdkrb1
uniprot id: A0A6I9L587
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: This is a receptor for bradykinin. Could be a factor in chronic pain and inflammation.

230844:Gabrb1
gene id: 230844:Gabrb1
uniprot id: A0A6I9LJF0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

230844:Spns2
gene id: 230844:Spns2
uniprot id: A0A6J0CDJ8
uniprot id: A0A6J0CGA0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Spinster (TC 2.A.1.49) family.
messages: Membrane

230844:LOC102920091
gene id: 230844:LOC102920091
uniprot id: A0A6I9LEF8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:LOC102916402
gene id: 230844:LOC102916402
uniprot id: A0A6J0CUT3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Gsc
gene id: 230844:Gsc
uniprot id: A0A6I9M714
names: Subcellular Location Annotation
messages: Nucleus

230844:Mix23
gene id: 230844:Mix23
uniprot id: A0A6I9LE39
uniprot id: A0A6J0D5P9
names: Similarity
messages: Belongs to the MIX23 family.

230844:Dxo
gene id: 230844:Dxo
uniprot id: A0A6J0CPL7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DXO/Dom3Z family.
messages: Binds 2 magnesium ions.
messages: Decapping enzyme for NAD-capped RNAs: specifically hydrolyzes the nicotinamide adenine dinucleotide (NAD) cap from a subset of RNAs by removing the entire NAD moiety from the 5'-end of an NAD-capped RNA.
messages: Nucleus

230844:LOC102923175
gene id: 230844:LOC102923175
uniprot id: A0A6J0CRB5
uniprot id: A0A6J0CTA3
names: Similarity
messages: Belongs to the glycine N-acyltransferase family.

230844:Cpxm2
gene id: 230844:Cpxm2
uniprot id: A0A6I9L4K3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M14 family.
messages: Secreted

230844:Thoc2
gene id: 230844:Thoc2
uniprot id: A0A6J0DKS2
uniprot id: A0A6J0DKX5
uniprot id: A0A6J0DL96
uniprot id: A0A6J0DS11
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the THOC2 family.
messages: Component of the THO complex, which is composed of THOC1, THOC2, THOC3, THOC5, THOC6 and THOC7; together with at least ALYREF/THOC4, DDX39B, SARNP/CIP29 and CHTOP, THO forms the transcription/export (TREX) complex which seems to have a dynamic structure involving ATP-dependent remodeling. Interacts with THOC1, POLDIP3 and ZC3H11A.
messages: Nucleus

230844:Tmprss2
gene id: 230844:Tmprss2
uniprot id: A0A6J0CUI1
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

230844:Mpp1
gene id: 230844:Mpp1
uniprot id: A0A6I9MJ69
names: Function
names: Subcellular Location Annotation
messages: Essential regulator of neutrophil polarity. Regulates neutrophil polarization by regulating AKT1 phosphorylation through a mechanism that is independent of PIK3CG activity.
messages: stereocilium

230844:Lrrc8e
gene id: 230844:Lrrc8e
uniprot id: A0A6J0ED98
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LRRC8 family.
messages: Cell membrane
messages: Membrane

230844:Atp8b2
gene id: 230844:Atp8b2
uniprot id: A0A6I9LBM5
uniprot id: A0A6J0D6C3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.
messages: Membrane

230844:Nudc
gene id: 230844:Nudc
uniprot id: A0A6I9LA90
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nudC family.
messages: Midbody
messages: spindle

230844:Irf2bp1
gene id: 230844:Irf2bp1
uniprot id: A0A6I9ME73
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IRF2BP family.
messages: Nucleus

230844:Ets1
gene id: 230844:Ets1
uniprot id: A0A6I9L9R0
uniprot id: A0A6J0DFT7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Cytoplasm
messages: Nucleus

230844:Bak1
gene id: 230844:Bak1
uniprot id: A0A6I9M5T8
names: Similarity
messages: Belongs to the Bcl-2 family.

230844:LOC102910346
gene id: 230844:LOC102910346
uniprot id: A0A6I9LHV8
names: Subcellular Location Annotation
messages: Cytoplasm

230844:Hm13
gene id: 230844:Hm13
uniprot id: A0A6I9LMZ1
uniprot id: A0A6I9LVE2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A22B family.
messages: Membrane

230844:Dmrta1
gene id: 230844:Dmrta1
uniprot id: A0A6I9LAD6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DMRT family.
messages: Nucleus

230844:C1H19orf54
gene id: 230844:C1H19orf54
uniprot id: A0A6I9M483
names: Similarity
messages: Belongs to the ACTMAP family.

230844:Puf60
gene id: 230844:Puf60
uniprot id: A0A6I9LS74
uniprot id: A0A6I9LWK4
uniprot id: A0A6I9M2S3
uniprot id: A0A6I9M8C7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRM half pint family.
messages: Nucleus

230844:Ftsj1
gene id: 230844:Ftsj1
uniprot id: A0A6I9MJ82
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. TRM7 subfamily.
messages: Cytoplasm
messages: Methylates the 2'-O-ribose of nucleotides at positions 32 and 34 of the tRNA anticodon loop of substrate tRNAs.

230844:LOC102905341
gene id: 230844:LOC102905341
uniprot id: A0A6I9L8Z1
names: Similarity
messages: Belongs to the beta/gamma-crystallin family.

230844:Slc5a9
gene id: 230844:Slc5a9
uniprot id: A0A6J0DB13
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Cell membrane
messages: Membrane

230844:Scamp4
gene id: 230844:Scamp4
uniprot id: A0A6I9LFF4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SCAMP family.
messages: Membrane

230844:Gjc3
gene id: 230844:Gjc3
uniprot id: A0A6J0CR11
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

230844:Slc25a15
gene id: 230844:Slc25a15
uniprot id: A0A6I9LQ33
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

230844:Bves
gene id: 230844:Bves
uniprot id: A0A6J0DS80
names: Similarity
messages: Belongs to the popeye family.

230844:LOC102919170
gene id: 230844:LOC102919170
uniprot id: A0A6I9MFX0
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Associates with the cytoplasmic CCR4-NOT deadenylase complex to trigger ARE-containing mRNA deadenylation and decay processes.
messages: Cytoplasm
messages: Nucleus
messages: Zinc-finger RNA-binding protein that destabilizes several cytoplasmic AU-rich element (ARE)-containing mRNA transcripts by promoting their poly(A) tail removal or deadenylation, and hence provide a mechanism for attenuating protein synthesis. Acts as a 3'-untranslated region (UTR) ARE mRNA-binding adapter protein to communicate signaling events to the mRNA decay machinery. Functions by recruiting the CCR4-NOT deadenylase complex and probably other components of the cytoplasmic RNA decay machinery to the bound ARE-containing mRNAs, and hence promotes ARE-mediated mRNA deadenylation and decay processes. Binds to 3'-UTR ARE of numerous mRNAs.

230844:Nsmce4a
gene id: 230844:Nsmce4a
uniprot id: A0A6I9LGZ2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NSE4 family.
messages: Component of the SMC5-SMC6 complex, that promotes sister chromatid alignment after DNA damage and facilitates double-stranded DNA breaks (DSBs) repair via homologous recombination between sister chromatids.
messages: Component of the SMC5-SMC6 complex.
messages: Nucleus
messages: telomere

230844:Atp6v0d1
gene id: 230844:Atp6v0d1
uniprot id: A0A6I9LYT3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the V-ATPase V0D/AC39 subunit family.
messages: Subunit of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment.
messages: V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex.

230844:Syndig1l
gene id: 230844:Syndig1l
uniprot id: A0A6I9LHC2
names: Similarity
messages: Belongs to the CD225/Dispanin family.

230844:Polr3gl
gene id: 230844:Polr3gl
uniprot id: A0A6I9LGU3
uniprot id: A0A6I9LP64
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic RPC7 RNA polymerase subunit family.
messages: Component of the RNA polymerase III (Pol III) complex.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs.
messages: Nucleus

230844:Dnal4
gene id: 230844:Dnal4
uniprot id: A0A6I9L8L5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dynein light chain family.
messages: cytoskeleton

230844:LOC102925660
gene id: 230844:LOC102925660
uniprot id: A0A6I9MF85
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor T2R family.
messages: Membrane

230844:Psmb7
gene id: 230844:Psmb7
uniprot id: A0A6I9ME78
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1B family.
messages: Component of the proteasome complex.
messages: Component of the proteasome, a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.
messages: Cytoplasm
messages: Nucleus

230844:Slc39a8
gene id: 230844:Slc39a8
uniprot id: A0A6I9KSK6
names: Subcellular Location Annotation
messages: Membrane

230844:Zar1
gene id: 230844:Zar1
uniprot id: A0A6I9L9K3
names: Similarity
names: Subunit
messages: Belongs to the ZAR1 family.
messages: Interacts with YBX2.

230844:Cpo
gene id: 230844:Cpo
uniprot id: A0A6I9LCT3
names: Similarity
messages: Belongs to the peptidase M14 family.

230844:LOC102909647
gene id: 230844:LOC102909647
uniprot id: A0A6J0CFC1
names: Similarity
messages: Belongs to the cytochrome P450 family.

230844:Asb10
gene id: 230844:Asb10
uniprot id: A0A6I9M1S1
names: Similarity
messages: Belongs to the ankyrin SOCS box (ASB) family.

230844:Rps6kb2
gene id: 230844:Rps6kb2
uniprot id: A0A6I9LL37
names: Similarity
messages: Belongs to the protein kinase superfamily.

230844:Myo1f
gene id: 230844:Myo1f
uniprot id: A0A6I9MB80
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.

230844:Igf1
gene id: 230844:Igf1
uniprot id: A0A6I9LBG0
uniprot id: A0A6I9LJS6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the insulin family.
messages: Secreted

230844:Yod1
gene id: 230844:Yod1
uniprot id: A0A6I9MF61
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Hydrolase that can remove conjugated ubiquitin from proteins and participates in endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by triming the ubiquitin chain on the associated substrate to facilitate their threading through the VCP/p97 pore. Cleaves both polyubiquitin and di-ubiquitin.

230844:LOC102916679
gene id: 230844:LOC102916679
uniprot id: A0A6I9KWI2
names: Function
messages: Modulates leading keratinocyte migration and cellular adhesion to matrix proteins during a wound-healing response and promotes wound repair. May play a role during trichilemmal differentiation of the hair follicle.

230844:Med1
gene id: 230844:Med1
uniprot id: A0A6I9KVI6
uniprot id: A0A6I9L223
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Mediator complex subunit 1 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Nucleus

230844:Sgca
gene id: 230844:Sgca
uniprot id: A0A6I9L299
names: Function
names: Similarity
messages: Belongs to the sarcoglycan alpha/epsilon family.
messages: Component of the sarcoglycan complex, a subcomplex of the dystrophin-glycoprotein complex which forms a link between the F-actin cytoskeleton and the extracellular matrix.

230844:Ap3b1
gene id: 230844:Ap3b1
uniprot id: A0A6I9LNS7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adaptor complexes large subunit family.
messages: Subunit of non-clathrin- and clathrin-associated adaptor protein complex 3 (AP-3) that plays a role in protein sorting in the late-Golgi/trans-Golgi network (TGN) and/or endosomes. The AP complexes mediate both the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules. AP-3 appears to be involved in the sorting of a subset of transmembrane proteins targeted to lysosomes and lysosome-related organelles. In concert with the BLOC-1 complex, AP-3 is required to target cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals.
messages: clathrin-coated vesicle membrane

230844:LOC102925852
gene id: 230844:LOC102925852
uniprot id: A0A6I9M7E1
names: Subcellular Location Annotation
names: Subunit
messages: Interacts with PTBP2; the interaction is direct.
messages: Nucleus

230844:Il6
gene id: 230844:Il6
uniprot id: A0A6I9M247
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IL-6 superfamily.
messages: Secreted

230844:Impdh1
gene id: 230844:Impdh1
uniprot id: A0A6I9LIT2
uniprot id: A0A6J0DKC0
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Could also have a single-stranded nucleic acid-binding activity and could play a role in RNA and/or DNA metabolism. It may also have a role in the development of malignancy and the growth progression of some tumors.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.
messages: Nucleus

230844:Arf1
gene id: 230844:Arf1
uniprot id: A0A6I9MI52
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Arf family.
messages: GTP-binding protein involved in protein trafficking; modulates vesicle budding and uncoating within the Golgi apparatus.
messages: Golgi apparatus

230844:LOC102911388
gene id: 230844:LOC102911388
uniprot id: A0A6I9LLI1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Cetn2
gene id: 230844:Cetn2
uniprot id: A0A6I9MA04
names: Similarity
messages: Belongs to the centrin family.

230844:Elp2
gene id: 230844:Elp2
uniprot id: A0A6I9LKA6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat ELP2 family.
messages: Cytoplasm
messages: Nucleus

230844:Eaf2
gene id: 230844:Eaf2
uniprot id: A0A6I9L340
names: Similarity
messages: Belongs to the EAF family.

230844:Vps18
gene id: 230844:Vps18
uniprot id: A0A6I9LLV6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VPS18 family.
messages: Membrane

230844:Wnt10b
gene id: 230844:Wnt10b
uniprot id: A0A6I9L7M1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

230844:Sh3gl2
gene id: 230844:Sh3gl2
uniprot id: A0A6I9L3P4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endophilin family.
messages: Membrane

230844:Cmklr2
gene id: 230844:Cmklr2
uniprot id: A0A6I9L903
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chemokine-like receptor (CMKLR) family.
messages: Cell membrane
messages: Membrane

230844:Tas2r38
gene id: 230844:Tas2r38
uniprot id: A0A6I9M772
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor T2R family.
messages: Membrane

230844:Fbl
gene id: 230844:Fbl
uniprot id: A0A6I9MCM2
names: Similarity
messages: Belongs to the methyltransferase superfamily. Fibrillarin family.

230844:Scn10a
gene id: 230844:Scn10a
uniprot id: A0A6I9LYH8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium channel (TC 1.A.1.10) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient.
messages: Membrane

230844:Pla2g4f
gene id: 230844:Pla2g4f
uniprot id: A0A6J0CVW7
names: Domain
names: Subcellular Location Annotation
messages: The N-terminal C2 domain associates with lipid membranes upon calcium binding.
messages: cytosol

230844:Smpx
gene id: 230844:Smpx
uniprot id: A0A6I9L5C2
names: Function
names: Similarity
messages: Belongs to the SMPX family.
messages: Plays a role in the regulatory network through which muscle cells coordinate their structural and functional states during growth, adaptation, and repair.

230844:Stard5
gene id: 230844:Stard5
uniprot id: A0A6I9M4L4
names: Function
messages: May be involved in the intracellular transport of sterols or other lipids. May bind cholesterol or other sterols.

230844:LOC102917534
gene id: 230844:LOC102917534
uniprot id: A0A6J0CTE7
names: Similarity
messages: Belongs to the PRAME family.

230844:Purg
gene id: 230844:Purg
uniprot id: A0A6I9L6U5
uniprot id: A0A6J0D063
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PUR DNA-binding protein family.
messages: Nucleus

230844:Clcn1
gene id: 230844:Clcn1
uniprot id: A0A6I9MLI3
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chloride channel (TC 2.A.49) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

230844:Kcnd3
gene id: 230844:Kcnd3
uniprot id: A0A6I9LXF9
uniprot id: A0A6J0E139
names: Subcellular Location Annotation
messages: Membrane
messages: dendrite

230844:Fam187a
gene id: 230844:Fam187a
uniprot id: A0A6I9KTR0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAM187 family.
messages: Membrane

230844:Chrna6
gene id: 230844:Chrna6
uniprot id: A0A6I9M8N3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

230844:Cnfn
gene id: 230844:Cnfn
uniprot id: A0A6I9LTT7
names: Similarity
messages: Belongs to the cornifelin family.

230844:LOC102925401
gene id: 230844:LOC102925401
uniprot id: A0A6I9LMZ6
names: Similarity
messages: Belongs to the enolase family.

230844:Dph2
gene id: 230844:Dph2
uniprot id: A0A6I9MN39
names: Function
names: Similarity
messages: Belongs to the DPH1/DPH2 family. DPH2 subfamily.
messages: Required for the first step of diphthamide biosynthesis, a post-translational modification of histidine which occurs in elongation factor 2. DPH1 and DPH2 transfer a 3-amino-3-carboxypropyl (ACP) group from S-adenosyl-L-methionine (SAM) to a histidine residue, the reaction is assisted by a reduction system comprising DPH3 and a NADH-dependent reductase. Facilitates the reduction of the catalytic iron-sulfur cluster found in the DPH1 subunit.

230844:Slc5a5
gene id: 230844:Slc5a5
uniprot id: A0A6I9LW86
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Cell membrane
messages: Membrane

230844:LOC102925349
gene id: 230844:LOC102925349
uniprot id: A0A6I9MHD0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Pan3
gene id: 230844:Pan3
uniprot id: A0A6I9LJB5
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the protein kinase superfamily. PAN3 family.
messages: Contains a pseudokinase domain. The protein kinase domain is predicted to be catalytically inactive because some of the residues important for catalytic activity are substituted and it lacks the equivalent of the binding site for a peptide substrate. However, it has retained an ATP-binding site and ATP-binding is required for mRNA degradation, stimulating the activity of the PAN2 nuclease in vitro. The nucleotide-binding site is juxtaposed to the RNase active site of PAN2 in the complex and may actually bind nucleosides of a poly(A) RNA rather than ATP, feeding the poly(A)-tail to the active site of the deadenylase and thus increasing the efficiency with which this distributive enzyme degrades oligo(A) RNAs.
messages: Homodimer. Forms a heterotrimer with a catalytic subunit PAN2 to form the poly(A)-nuclease (PAN) deadenylation complex. Interacts (via PAM-2 motif) with poly(A)-binding protein PABPC1 (via PABC domain), conferring substrate specificity of the enzyme complex. Interacts with the GW182 family proteins TNRC6A, TNRC6B and TNRC6C.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: P-body
messages: Regulatory subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in general and miRNA-mediated mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein (PABP). PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent mRNA decaping and subsequent 5'-3' exonucleolytic degradation by XRN1. PAN3 acts as a positive regulator for PAN activity, recruiting the catalytic subunit PAN2 to mRNA via its interaction with RNA and PABP, and to miRNA targets via its interaction with GW182 family proteins.
messages: The N-terminal zinc finger binds to poly(A) RNA.
messages: The pseudokinase domain, the coiled-coil (CC), and C-terminal knob domain (CK) form a structural unit (PKC) that forms an extensive high-affinity interaction surface for PAN2.

230844:Npy1r
gene id: 230844:Npy1r
uniprot id: A0A6J0DZY5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

230844:LOC102914776
gene id: 230844:LOC102914776
uniprot id: A0A6I9M9C3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Pex13
gene id: 230844:Pex13
uniprot id: A0A6I9L1A5
names: Similarity
messages: Belongs to the peroxin-13 family.

230844:Hoxa5
gene id: 230844:Hoxa5
uniprot id: A0A6I9LG39
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Antp homeobox family.
messages: Nucleus

230844:Vps37a
gene id: 230844:Vps37a
uniprot id: A0A6I9L6P5
uniprot id: A0A6J0D431
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VPS37 family.
messages: Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies. May be involved in cell growth and differentiation.
messages: Endosome membrane
messages: Late endosome membrane

230844:Atl3
gene id: 230844:Atl3
uniprot id: A0A6I9LQP3
names: Similarity
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. GB1/RHD3 GTPase family.

230844:Kcmf1
gene id: 230844:Kcmf1
uniprot id: A0A6I9LQ96
names: Function
names: Similarity
messages: Belongs to the KCMF1 family.
messages: Has intrinsic E3 ubiquitin ligase activity and promotes ubiquitination.

230844:Bambi
gene id: 230844:Bambi
uniprot id: A0A6I9LXH3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BAMBI family.
messages: Membrane
messages: Negatively regulates TGF-beta signaling.

230844:Tmem9
gene id: 230844:Tmem9
uniprot id: A0A6I9LEU5
uniprot id: A0A6J0DN97
names: Similarity
messages: Belongs to the TMEM9 family.

230844:Shmt2
gene id: 230844:Shmt2
uniprot id: A0A6I9L549
names: Function
names: Similarity
messages: Belongs to the SHMT family.
messages: Interconversion of serine and glycine.

230844:LOC102906308
gene id: 230844:LOC102906308
uniprot id: A0A6I9LNW3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bZIP family.
messages: Homodimer; binds DNA as homodimer. Heterodimer; heterodimerizes with other members of ATF family and with JUN family members.
messages: Nucleus
messages: Stress-responsive chromatin regulator that plays a role in various biological processes including innate immunological memory, adipocyte differentiation or telomerase regulation. In absence of stress, contributes to the formation of heterochromatin and heterochromatin-like structure by recruiting histone H3K9 tri- and di-methyltransferases thus silencing the transcription of target genes such as STAT1 in adipocytes, or genes involved in innate immunity in macrophages and adipocytes. Stress induces ATF7 phosphorylation that disrupts interactions with histone methyltransferase and enhances the association with coactivators containing histone acetyltransferase and/or histone demethylase, leading to disruption of the heterochromatin-like structure and subsequently transcriptional activation. In response to TNF-alpha, which is induced by various stresses, phosphorylated ATF7 and telomerase are released from telomeres leading to telomere shortening.

230844:Pkp3
gene id: 230844:Pkp3
uniprot id: A0A6J0D8X3
names: Similarity
messages: Belongs to the beta-catenin family.

230844:Hspa1l
gene id: 230844:Hspa1l
uniprot id: A0A6I9MF26
names: Similarity
messages: Belongs to the heat shock protein 70 family.

230844:LOC102921037
gene id: 230844:LOC102921037
uniprot id: A0A6I9MQS9
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

230844:LOC102915750
gene id: 230844:LOC102915750
uniprot id: A0A6I9M0R4
names: Cofactor
names: Similarity
messages: Belongs to the transglutaminase superfamily. Transglutaminase family.
messages: Binds 1 Ca(2+) ion per subunit.

230844:Mllt1
gene id: 230844:Mllt1
uniprot id: A0A6J0DMQ3
names: Subcellular Location Annotation
messages: Nucleus

230844:Mbtd1
gene id: 230844:Mbtd1
uniprot id: A0A6J0E6M9
uniprot id: A0A6J0E8F0
uniprot id: A0A6J0EA70
names: Subcellular Location Annotation
messages: Nucleus

230844:Hoxc8
gene id: 230844:Hoxc8
uniprot id: A0A6I9LFC4
names: Subcellular Location Annotation
messages: Nucleus

230844:Rad23b
gene id: 230844:Rad23b
uniprot id: A0A6I9LVC3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RAD23 family.
messages: Cytoplasm
messages: Multiubiquitin chain receptor involved in modulation of proteasomal degradation. Involved in nucleotide excision repair.
messages: Nucleus

230844:Cfl2
gene id: 230844:Cfl2
uniprot id: A0A6I9MBF8
names: Similarity
messages: Belongs to the actin-binding proteins ADF family.

230844:Pick1
gene id: 230844:Pick1
uniprot id: A0A6I9LI41
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Probable adapter protein that bind to and organize the subcellular localization of a variety of membrane proteins containing some PDZ recognition sequence. Involved in the clustering of various receptors, possibly by acting at the receptor internalization level. Plays a role in synaptic plasticity by regulating the trafficking and internalization of AMPA receptors. May be regulated upon PRKCA activation. May regulate ASIC1/ASIC3 channel. Regulates actin polymerization by inhibiting the actin-nucleating activity of the Arp2/3 complex; the function is competitive with nucleation promoting factors and is linked to neuronal morphology regulation and AMPA receptor (AMPAR) endocytosis. Via interaction with the Arp2/3 complex involved in regulation of synaptic plasicity of excitatory synapses and required for spine shrinkage during long-term depression (LTD). Involved in regulation of astrocyte morphology, antagonistic to Arp2/3 complex activator WASL/N-WASP function.
messages: cytoskeleton
messages: perinuclear region
messages: synaptosome

230844:Smg9
gene id: 230844:Smg9
uniprot id: A0A6I9M655
names: Similarity
messages: Belongs to the SMG9 family.

230844:Galnt5
gene id: 230844:Galnt5
uniprot id: A0A6I9LYJ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
messages: Golgi apparatus membrane
messages: Membrane

230844:LOC102924725
gene id: 230844:LOC102924725
uniprot id: A0A6I9MI90
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor T2R family.
messages: Membrane

230844:Atp5po
gene id: 230844:Atp5po
uniprot id: A0A6I9LR83
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase delta chain family.
messages: Membrane
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain and the peripheric stalk, which acts as a stator to hold the catalytic alpha(3)beta(3) subcomplex and subunit a/ATP6 static relative to the rotary elements.
messages: Mitochondrion inner membrane

230844:Nt5e
gene id: 230844:Nt5e
uniprot id: A0A6I9LSH7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 5'-nucleotidase family.
messages: Membrane

230844:LOC102908646
gene id: 230844:LOC102908646
uniprot id: A0A6I9LG88
names: Similarity
messages: Belongs to the cytochrome P450 family.

230844:Mrps33
gene id: 230844:Mrps33
uniprot id: A0A6I9M4Z3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mS33 family.
messages: Mitochondrion

230844:Tubb
gene id: 230844:Tubb
uniprot id: A0A6I9MI92
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.
messages: cytoskeleton

230844:Pdia2
gene id: 230844:Pdia2
uniprot id: A0A6J0DE46
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein disulfide isomerase family.
messages: Endoplasmic reticulum lumen

230844:Lap3
gene id: 230844:Lap3
uniprot id: A0A6I9LSW9
names: Similarity
names: Subunit
messages: Belongs to the peptidase M17 family.
messages: Homohexamer.

230844:Acta1
gene id: 230844:Acta1
uniprot id: A0A6I9M0F0
names: Similarity
messages: Belongs to the actin family.

230844:LOC102927490
gene id: 230844:LOC102927490
uniprot id: A0A6I9ME03
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:LOC102908284
gene id: 230844:LOC102908284
uniprot id: A0A6I9KUV8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome P450 family.
messages: Cytochromes P450 are a group of heme-thiolate monooxygenases. They oxidize a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Microsome membrane

230844:Actn4
gene id: 230844:Actn4
uniprot id: A0A6I9LE00
uniprot id: A0A6I9LN06
uniprot id: A0A6I9LTR6
uniprot id: A0A6J0DM24
uniprot id: A0A6J0DMF9
names: Similarity
messages: Belongs to the alpha-actinin family.

230844:Clrn3
gene id: 230844:Clrn3
uniprot id: A0A6I9LP43
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the clarin family.
messages: Membrane

230844:LOC102918218
gene id: 230844:LOC102918218
uniprot id: A0A6I9M979
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Mok
gene id: 230844:Mok
uniprot id: A0A6I9LXB8
uniprot id: A0A6J0CDA8
uniprot id: A0A6J0CDB3
uniprot id: A0A6J0CF04
uniprot id: A0A6J0CFE2
uniprot id: A0A6J0CG22
names: Similarity
messages: Belongs to the protein kinase superfamily.

230844:Mark3
gene id: 230844:Mark3
uniprot id: A0A6I9LPX5
uniprot id: A0A6J0E0Z2
uniprot id: A0A6J0E2Q7
uniprot id: A0A6J0E2R2
uniprot id: A0A6J0E5W2
uniprot id: A0A6J0E5W7
uniprot id: A0A6J0E8Q1
uniprot id: A0A6J0E8Q6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. SNF1 subfamily.
messages: dendrite

230844:LOC102919882
gene id: 230844:LOC102919882
uniprot id: A0A6I9M6S0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Panx2
gene id: 230844:Panx2
uniprot id: A0A6I9LF42
uniprot id: A0A6J0D603
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pannexin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Structural component of the gap junctions and the hemichannels.
messages: gap junction

230844:Cdc14b
gene id: 230844:Cdc14b
uniprot id: A0A6I9LDI3
uniprot id: A0A6J0DIQ2
uniprot id: A0A6J0DL41
uniprot id: A0A6J0DL46
uniprot id: A0A6J0DLC4
uniprot id: A0A6J0DLP0
uniprot id: A0A6J0DLP5
uniprot id: A0A6J0DSH5
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class CDC14 subfamily.

230844:Aspa
gene id: 230844:Aspa
uniprot id: A0A6I9M3P0
names: Cofactor
names: Similarity
messages: Belongs to the AspA/AstE family. Aspartoacylase subfamily.
messages: Binds 1 zinc ion per subunit.

230844:LOC102908799
gene id: 230844:LOC102908799
uniprot id: A0A6I9LUV9
names: Similarity
messages: Belongs to the ubiquitin family.

230844:Cblb
gene id: 230844:Cblb
uniprot id: A0A6I9LYD2
uniprot id: A0A6I9M5L4
names: Domain
names: Function
messages: E3 ubiquitin-protein ligase which accepts ubiquitin from specific E2 ubiquitin-conjugating enzymes, and transfers it to substrates, generally promoting their degradation by the proteasome.
messages: The N-terminus is composed of the phosphotyrosine binding (PTB) domain, a short linker region and the RING-type zinc finger. The PTB domain, which is also called TKB (tyrosine kinase binding) domain, is composed of three different subdomains: a four-helix bundle (4H), a calcium-binding EF hand and a divergent SH2 domain.

230844:LOC102906760
gene id: 230844:LOC102906760
uniprot id: A0A6I9KVP2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Acsf2
gene id: 230844:Acsf2
uniprot id: A0A6I9L2Q9
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

230844:Dennd11
gene id: 230844:Dennd11
uniprot id: A0A6I9MLE1
names: Similarity
messages: Belongs to the DENND11 family.

230844:Ogdh
gene id: 230844:Ogdh
uniprot id: A0A6I9KXM5
uniprot id: A0A6J0CVW4
uniprot id: A0A6J0CWK2
names: Similarity
messages: Belongs to the alpha-ketoglutarate dehydrogenase family.

230844:Smg7
gene id: 230844:Smg7
uniprot id: A0A6I9LJX1
uniprot id: A0A6J0DG95
uniprot id: A0A6J0DGB4
names: Function
names: Subcellular Location Annotation
messages: Nucleus
messages: Plays a role in nonsense-mediated mRNA decay.

230844:Antkmt
gene id: 230844:Antkmt
uniprot id: A0A6I9L7X3
uniprot id: A0A6J0DBN8
uniprot id: A0A6J0DDF6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ANT/ATPSC lysine N-methyltransferase family.
messages: Mitochondrion membrane

230844:LOC102917024
gene id: 230844:LOC102917024
uniprot id: A0A6I9MJ24
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Mrpl36
gene id: 230844:Mrpl36
uniprot id: A0A6I9M466
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

230844:Slit3
gene id: 230844:Slit3
uniprot id: A0A6J0DXG8
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

230844:Ufc1
gene id: 230844:Ufc1
uniprot id: A0A6I9MAV9
names: Function
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family. UFC1 subfamily.
messages: E1-like enzyme which specifically catalyzes the second step in ufmylation. Ufmylation is involved in reticulophagy (also called ER-phagy) induced in response to endoplasmic reticulum stress.

230844:Wscd2
gene id: 230844:Wscd2
uniprot id: A0A6I9M5P4
names: Function
names: Similarity
messages: Belongs to the WSCD family.
messages: Sialate:O-sulfotransferase which catalyzes 8-O-sulfation at the Sia-glycan level using 3'-phosphoadenosine 5'-phosphosulfate (PAPS) as a donor, forming 8-O-sulfated Sia (Sia8S)-glycans.

230844:Mmp7
gene id: 230844:Mmp7
uniprot id: A0A6I9LX63
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M10A family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Can bind about 5 Ca(2+) ions per subunit.

230844:Fgfr1op2
gene id: 230844:Fgfr1op2
uniprot id: A0A6I9LXX9
uniprot id: A0A6J0DXE4
names: Similarity
messages: Belongs to the SIKE family.

230844:Cnrip1
gene id: 230844:Cnrip1
uniprot id: A0A6I9MGT2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CNRIP family.
messages: Interacts with the cannabinoid receptor CNR1 (via C-terminus). Does not interact with cannabinoid receptor CNR2.
messages: Suppresses cannabinoid receptor CNR1-mediated tonic inhibition of voltage-gated calcium channels.

230844:Qsox2
gene id: 230844:Qsox2
uniprot id: A0A6I9LR77
names: Function
names: Similarity
messages: Belongs to the quiescin-sulfhydryl oxidase (QSOX) family.
messages: Catalyzes the oxidation of sulfhydryl groups in peptide and protein thiols to disulfides with the reduction of oxygen to hydrogen peroxide.

230844:Slc44a1
gene id: 230844:Slc44a1
uniprot id: A0A6I9ME49
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CTL (choline transporter-like) family.
messages: Cell membrane
messages: Choline transporter.
messages: Membrane

230844:Ppp6r2
gene id: 230844:Ppp6r2
uniprot id: A0A6J0D4X7
names: Similarity
messages: Belongs to the SAPS family.

230844:Rnaseh2b
gene id: 230844:Rnaseh2b
uniprot id: A0A6I9LI84
uniprot id: A0A6I9LTJ7
uniprot id: A0A6J0DQP0
uniprot id: A0A6J0DU03
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase H2 subunit B family.
messages: Non catalytic subunit of RNase H2, an endonuclease that specifically degrades the RNA of RNA:DNA hybrids. Participates in DNA replication, possibly by mediating the removal of lagging-strand Okazaki fragment RNA primers during DNA replication. Mediates the excision of single ribonucleotides from DNA:RNA duplexes.
messages: Nucleus
messages: The RNase H2 complex is a heterotrimer composed of the catalytic subunit RNASEH2A and the non-catalytic subunits RNASEH2B and RNASEH2C.

230844:Dync1h1
gene id: 230844:Dync1h1
uniprot id: A0A6I9LXB2
uniprot id: A0A6J0CG12
names: Similarity
messages: Belongs to the dynein heavy chain family.

230844:Gpr183
gene id: 230844:Gpr183
uniprot id: A0A6J0DBI2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Agpat1
gene id: 230844:Agpat1
uniprot id: A0A6I9MF13
names: Domain
names: Function
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.
messages: Converts 1-acyl-sn-glycerol-3-phosphate (lysophosphatidic acid or LPA) into 1,2-diacyl-sn-glycerol-3-phosphate (phosphatidic acid or PA) by incorporating an acyl moiety at the sn-2 position of the glycerol backbone.
messages: The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate.

230844:Tamm41
gene id: 230844:Tamm41
uniprot id: A0A6I9LKC7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAM41 family.
messages: Catalyzes the conversion of phosphatidic acid (PA) to CDP-diacylglycerol (CDP-DAG), an essential intermediate in the synthesis of phosphatidylglycerol, cardiolipin and phosphatidylinositol.
messages: Mitochondrion inner membrane

230844:LOC102921768
gene id: 230844:LOC102921768
uniprot id: A0A6I9LRN3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S1 family.
messages: Membrane

230844:LOC102912960
gene id: 230844:LOC102912960
uniprot id: A0A6J0CRH1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:LOC102904032
gene id: 230844:LOC102904032
uniprot id: A0A6I9LIP2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPOT14 family.
messages: Cytoplasm
messages: Nucleus

230844:Nipal4
gene id: 230844:Nipal4
uniprot id: A0A6I9MIE2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NIPA family.
messages: Membrane

230844:Ggnbp2
gene id: 230844:Ggnbp2
uniprot id: A0A6I9LHY2
uniprot id: A0A6J0DMS4
uniprot id: A0A6J0DPU2
uniprot id: A0A6J0DQG9
names: Function
messages: May be involved in spermatogenesis.

230844:LOC102912153
gene id: 230844:LOC102912153
uniprot id: A0A6I9LJK0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:LOC102922927
gene id: 230844:LOC102922927
uniprot id: A0A6J0EC68
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

230844:LOC102914926
gene id: 230844:LOC102914926
uniprot id: A0A6I9MIC7
uniprot id: A0A6I9MKJ6
names: Similarity
messages: Belongs to the LSM14 family.

230844:Prkar2a
gene id: 230844:Prkar2a
uniprot id: A0A6I9L8A2
uniprot id: A0A6I9LFL6
uniprot id: A0A6J0DA43
uniprot id: A0A6J0DBY0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cAMP-dependent kinase regulatory chain family.
messages: Cell membrane
messages: Membrane

230844:Kcnq4
gene id: 230844:Kcnq4
uniprot id: A0A6J0E2B8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

230844:LOC102908495
gene id: 230844:LOC102908495
uniprot id: A0A6I9LXS2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Irx1
gene id: 230844:Irx1
uniprot id: A0A6I9M5L9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TALE/IRO homeobox family.
messages: Nucleus

230844:LOC102917028
gene id: 230844:LOC102917028
uniprot id: A0A6I9MP25
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Tspan32
gene id: 230844:Tspan32
uniprot id: A0A6I9LDN8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

230844:Htra2
gene id: 230844:Htra2
uniprot id: A0A6I9MCM6
names: Similarity
messages: Belongs to the peptidase S1C family.

230844:Clrn1
gene id: 230844:Clrn1
uniprot id: A0A6I9MG35
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the clarin family.
messages: Membrane

230844:LOC102902792
gene id: 230844:LOC102902792
uniprot id: A0A6I9L7R6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Tm2d3
gene id: 230844:Tm2d3
uniprot id: A0A6I9L2L0
uniprot id: A0A6I9LAQ4
names: Subcellular Location Annotation
messages: Membrane

230844:Dync1li2
gene id: 230844:Dync1li2
uniprot id: A0A6I9L8Q3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes.
messages: Belongs to the dynein light intermediate chain family.
messages: Homodimer. The cytoplasmic dynein 1 complex consists of two catalytic heavy chains (HCs) and a number of non-catalytic subunits presented by intermediate chains (ICs).
messages: cytoskeleton

230844:Cenph
gene id: 230844:Cenph
uniprot id: A0A6I9LQK1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CENP-H/MCM16 family.
messages: Nucleus
messages: kinetochore

230844:LOC102910874
gene id: 230844:LOC102910874
uniprot id: A0A6J0DGY7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome P450 family.
messages: Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.
messages: Endoplasmic reticulum membrane
messages: Microsome membrane

230844:Zdhhc19
gene id: 230844:Zdhhc19
uniprot id: A0A6I9L847
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

230844:Slc35b4
gene id: 230844:Slc35b4
uniprot id: A0A6I9M4X3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleotide-sugar transporter family. SLC35B subfamily.
messages: Membrane

230844:LOC102918489
gene id: 230844:LOC102918489
uniprot id: A0A6I9LTY2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cystatin family.
messages: Secreted

230844:Fabp4
gene id: 230844:Fabp4
uniprot id: A0A6I9LIZ8
names: Similarity
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.

230844:Pigv
gene id: 230844:Pigv
uniprot id: A0A6I9L289
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PIGV family.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mannosyltransferase involved in glycosylphosphatidylinositol-anchor biosynthesis.
messages: Membrane

230844:LOC102927103
gene id: 230844:LOC102927103
uniprot id: A0A6I9LE06
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Phactr1
gene id: 230844:Phactr1
uniprot id: A0A6I9KXA6
uniprot id: A0A6I9L4H7
uniprot id: A0A6J0CTS0
uniprot id: A0A6J0CU78
uniprot id: A0A6J0CU91
uniprot id: A0A6J0CU95
names: Similarity
names: Subunit
messages: Belongs to the phosphatase and actin regulator family.
messages: Binds PPP1CA and actin.

230844:Rexo4
gene id: 230844:Rexo4
uniprot id: A0A6I9MAB9
names: Similarity
messages: Belongs to the REXO4 family.

230844:B3galt2
gene id: 230844:B3galt2
uniprot id: A0A6I9L2D7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane

230844:Fam3a
gene id: 230844:Fam3a
uniprot id: A0A6J0CGG7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAM3 family.
messages: Secreted

230844:LOC102927689
gene id: 230844:LOC102927689
uniprot id: A0A6I9MF78
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:LOC102906437
gene id: 230844:LOC102906437
uniprot id: A0A6J0E404
names: Subcellular Location Annotation
messages: Chromosome

230844:Ppp1cb
gene id: 230844:Ppp1cb
uniprot id: A0A6J0E9N8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PPP phosphatase family. PP-1 subfamily.
messages: nucleolus
messages: nucleoplasm

230844:LOC102907247
gene id: 230844:LOC102907247
uniprot id: A0A6J0E4C2
names: Similarity
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. GB1/RHD3 GTPase family.

230844:Sdha
gene id: 230844:Sdha
uniprot id: A0A6I9M5N7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
messages: Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).
messages: Mitochondrion inner membrane

230844:Riok1
gene id: 230844:Riok1
uniprot id: A0A6I9L7L4
uniprot id: A0A6J0CTC3
names: Similarity
messages: Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family.

230844:Mrpl9
gene id: 230844:Mrpl9
uniprot id: A0A6I9M9J1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.

230844:Hk3
gene id: 230844:Hk3
uniprot id: A0A6I9LCQ0
names: Similarity
messages: Belongs to the hexokinase family.

230844:LOC102908378
gene id: 230844:LOC102908378
uniprot id: A0A6I9KT58
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

230844:Slc4a11
gene id: 230844:Slc4a11
uniprot id: A0A6I9LKW5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anion exchanger (TC 2.A.31) family.
messages: Cell membrane
messages: Membrane

230844:Dtna
gene id: 230844:Dtna
uniprot id: A0A6I9MI86
uniprot id: A0A6J0CJZ1
uniprot id: A0A6J0CKW3
uniprot id: A0A6J0CMB0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dystrophin family. Dystrobrevin subfamily.
messages: Cytoplasm

230844:Nfe2
gene id: 230844:Nfe2
uniprot id: A0A6I9LDM4
names: Similarity
messages: Belongs to the bZIP family. CNC subfamily.

230844:LOC102925753
gene id: 230844:LOC102925753
uniprot id: A0A6I9KY12
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

230844:Junb
gene id: 230844:Junb
uniprot id: A0A6I9MP50
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bZIP family. Jun subfamily.
messages: Nucleus

230844:Lig1
gene id: 230844:Lig1
uniprot id: A0A6I9MPR5
names: Similarity
messages: Belongs to the ATP-dependent DNA ligase family.

230844:Cdh7
gene id: 230844:Cdh7
uniprot id: A0A6I9M558
names: Function
names: Subcellular Location Annotation
messages: Cadherins are calcium-dependent cell adhesion proteins.
messages: Cell membrane
messages: Membrane

230844:Sprn
gene id: 230844:Sprn
uniprot id: A0A6J0E035
names: Function
names: Similarity
messages: Belongs to the SPRN family.
messages: Prion-like protein that has PrP(C)-like neuroprotective activity. May act as a modulator for the biological actions of normal and abnormal PrP.

230844:Col4a1
gene id: 230844:Col4a1
uniprot id: A0A6I9LS25
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Type IV collagen is the major structural component of glomerular basement membranes (GBM), forming a 'chicken-wire' meshwork together with laminins, proteoglycans and entactin/nidogen.
messages: basement membrane

230844:LOC102906082
gene id: 230844:LOC102906082
uniprot id: A0A6I9MCG9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Iws1
gene id: 230844:Iws1
uniprot id: A0A6I9L6D1
uniprot id: A0A6J0DBE9
names: Subcellular Location Annotation
messages: Nucleus

230844:Comtd1
gene id: 230844:Comtd1
uniprot id: A0A6I9LYU5
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-dependent O-methyltransferase family.

230844:Snap91
gene id: 230844:Snap91
uniprot id: A0A6I9LHB1
uniprot id: A0A6I9LX16
uniprot id: A0A6J0DSF1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PICALM/SNAP91 family.
messages: Membrane

230844:LOC102905925
gene id: 230844:LOC102905925
uniprot id: A0A6I9LNI4
names: Similarity
messages: Belongs to the PRAME family.

230844:LOC102911673
gene id: 230844:LOC102911673
uniprot id: A0A6I9MIZ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Toll-like receptor family.
messages: Membrane

230844:Akt1
gene id: 230844:Akt1
uniprot id: A0A6I9M5Y2
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. RAC subfamily.

230844:Wnt2
gene id: 230844:Wnt2
uniprot id: A0A6I9M6L4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

230844:Rell1
gene id: 230844:Rell1
uniprot id: A0A6I9L0X1
names: Similarity
messages: Belongs to the RELT family.

230844:LOC102921423
gene id: 230844:LOC102921423
uniprot id: A0A6I9MHK3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Cibar1
gene id: 230844:Cibar1
uniprot id: A0A6I9LCI9
uniprot id: A0A6J0D2F2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CIBAR family.
messages: centriole
messages: cilium basal body

230844:Rpp14
gene id: 230844:Rpp14
uniprot id: A0A6I9M9F2
names: Similarity
messages: Belongs to the eukaryotic/archaeal RNase P protein component 2 family.

230844:Stk10
gene id: 230844:Stk10
uniprot id: A0A6I9LL24
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.
messages: Cell membrane

230844:Thtpa
gene id: 230844:Thtpa
uniprot id: A0A6I9LQW1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ThTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Hydrolase highly specific for thiamine triphosphate (ThTP).
messages: Monomer.

230844:Degs2
gene id: 230844:Degs2
uniprot id: A0A6I9KV75
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fatty acid desaturase type 1 family. DEGS subfamily.
messages: Endoplasmic reticulum membrane
messages: Membrane

230844:Chst3
gene id: 230844:Chst3
uniprot id: A0A6I9L447
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 1 family. Gal/GlcNAc/GalNAc subfamily.
messages: Membrane

230844:LOC102923298
gene id: 230844:LOC102923298
uniprot id: A0A6I9LDE4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Gpr4
gene id: 230844:Gpr4
uniprot id: A0A6I9ME82
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:LOC102917772
gene id: 230844:LOC102917772
uniprot id: A0A6I9LUQ1
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Receptor class 3 subfamily.

230844:Nrg1
gene id: 230844:Nrg1
uniprot id: A0A6I9KZG1
uniprot id: A0A6I9KZJ7
uniprot id: A0A6I9L6U0
uniprot id: A0A6I9LA84
uniprot id: A0A6J0CYG4
uniprot id: A0A6J0CYG8
uniprot id: A0A6J0CZB0
uniprot id: A0A6J0CZB5
uniprot id: A0A6J0D0T4
uniprot id: A0A6J0D0T9
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the neuregulin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Secreted

230844:Lyar
gene id: 230844:Lyar
uniprot id: A0A6I9LVV2
names: Subcellular Location Annotation
messages: Cytoplasm

230844:LOC102909711
gene id: 230844:LOC102909711
uniprot id: A0A6I9LCW7
uniprot id: A0A6I9LSD5
names: Subcellular Location Annotation
messages: Membrane

230844:LOC102924537
gene id: 230844:LOC102924537
uniprot id: A0A6I9LEB4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome c oxidase subunit 6c family.
messages: Component of the cytochrome c oxidase (complex IV, CIV), a multisubunit enzyme composed of 14 subunits. The complex is composed of a catalytic core of 3 subunits MT-CO1, MT-CO2 and MT-CO3, encoded in the mitochondrial DNA, and 11 supernumerary subunits COX4I, COX5A, COX5B, COX6A, COX6B, COX6C, COX7A, COX7B, COX7C, COX8 and NDUFA4, which are encoded in the nuclear genome. The complex exists as a monomer or a dimer and forms supercomplexes (SCs) in the inner mitochondrial membrane with NADH-ubiquinone oxidoreductase (complex I, CI) and ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII), resulting in different assemblies (supercomplex SCI(1)III(2)IV(1) and megacomplex MCI(2)III(2)IV(2)).
messages: Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)). The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
messages: Mitochondrion inner membrane

230844:LOC102910434
gene id: 230844:LOC102910434
uniprot id: A0A6I9MGG2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Fam136a
gene id: 230844:Fam136a
uniprot id: A0A6I9LU39
names: Similarity
messages: Belongs to the FAM136 family.

230844:Myorg
gene id: 230844:Myorg
uniprot id: A0A6I9LWS0
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.

230844:Papolb
gene id: 230844:Papolb
uniprot id: A0A6J0CH11
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the poly(A) polymerase family.
messages: Nucleus

230844:Ppox
gene id: 230844:Ppox
uniprot id: A0A6I9M5F5
uniprot id: A0A6J0EFA9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protoporphyrinogen/coproporphyrinogen oxidase family. Protoporphyrinogen oxidase subfamily.
messages: Binds 1 FAD per subunit.
messages: Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX.
messages: Mitochondrion inner membrane

230844:Paqr8
gene id: 230844:Paqr8
uniprot id: A0A6J0ECH1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ADIPOR family.
messages: Membrane

230844:Cacna1s
gene id: 230844:Cacna1s
uniprot id: A0A6I9LGH8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family.
messages: Membrane
messages: Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death.

230844:LOC102906050
gene id: 230844:LOC102906050
uniprot id: A0A6I9MA75
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Actrt3
gene id: 230844:Actrt3
uniprot id: A0A6I9KUN3
names: Similarity
messages: Belongs to the actin family.

230844:Fbln1
gene id: 230844:Fbln1
uniprot id: A0A6I9LJJ9
uniprot id: A0A6I9LPG7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the fibulin family.
messages: Homomultimerizes and interacts with various extracellular matrix components.
messages: Incorporated into fibronectin-containing matrix fibers. May play a role in cell adhesion and migration along protein fibers within the extracellular matrix (ECM). Could be important for certain developmental processes and contribute to the supramolecular organization of ECM architecture, in particular to those of basement membranes.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

230844:Usp24
gene id: 230844:Usp24
uniprot id: A0A6I9LRS0
names: Similarity
messages: Belongs to the peptidase C19 family.

230844:Bace1
gene id: 230844:Bace1
uniprot id: A0A6I9M9J0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A1 family.
messages: Endosome
messages: Membrane
messages: Membrane raft
messages: Recycling endosome
messages: trans-Golgi network

230844:Htr7
gene id: 230844:Htr7
uniprot id: A0A6I9M7T6
uniprot id: A0A6J0E5B1
uniprot id: A0A6J0E6Z9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Cdk2
gene id: 230844:Cdk2
uniprot id: A0A6I9LNP3
uniprot id: A0A6I9M4E3
names: Similarity
messages: Belongs to the protein kinase superfamily.

230844:LOC102925948
gene id: 230844:LOC102925948
uniprot id: A0A6I9LWL9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:LOC102918259
gene id: 230844:LOC102918259
uniprot id: A0A6J0CTH2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. Very large inducible GTPase (VLIG) family.
messages: Nucleus

230844:Gad1
gene id: 230844:Gad1
uniprot id: A0A6I9L3B3
names: Similarity
names: Subunit
messages: Belongs to the group II decarboxylase family.
messages: Homodimer.

230844:LOC102926749
gene id: 230844:LOC102926749
uniprot id: A0A6I9LPW6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PMG family.
messages: In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins.
messages: Interacts with hair keratins.

230844:LOC102915247
gene id: 230844:LOC102915247
uniprot id: A0A6I9M610
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Insrr
gene id: 230844:Insrr
uniprot id: A0A6I9L4I0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. Insulin receptor subfamily.
messages: Membrane

230844:Znf711
gene id: 230844:Znf711
uniprot id: A0A6J0CPS6
names: Subcellular Location Annotation
messages: Nucleus

230844:Rrp1
gene id: 230844:Rrp1
uniprot id: A0A6I9LWX9
uniprot id: A0A6J0EC46
names: Similarity
messages: Belongs to the RRP1 family.

230844:Mc4r
gene id: 230844:Mc4r
uniprot id: A0A6I9KYB5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Receptor specific to the heptapeptide core common to adrenocorticotropic hormone and alpha-, beta-, and gamma-MSH. Plays a central role in energy homeostasis and somatic growth. This receptor is mediated by G proteins that stimulate adenylate cyclase (cAMP).

230844:LOC102909189
gene id: 230844:LOC102909189
uniprot id: A0A6J0DIW3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calycin superfamily. Lipocalin family.
messages: Secreted

230844:LOC102911393
gene id: 230844:LOC102911393
uniprot id: A0A6I9MAZ4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2A family.
messages: Chromosome
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

230844:Ip6k2
gene id: 230844:Ip6k2
uniprot id: A0A6I9LJU5
names: Similarity
messages: Belongs to the inositol phosphokinase (IPK) family.

230844:Tmco4
gene id: 230844:Tmco4
uniprot id: A0A6J0DIM8
uniprot id: A0A6J0DIY4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMCO4 family.
messages: Membrane

230844:Ap1g2
gene id: 230844:Ap1g2
uniprot id: A0A6J0E477
names: Similarity
messages: Belongs to the adaptor complexes large subunit family.

230844:LOC102906078
gene id: 230844:LOC102906078
uniprot id: A0A6I9MLC7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Itih5
gene id: 230844:Itih5
uniprot id: A0A6I9LIE7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ITIH family.
messages: Secreted

230844:Got2
gene id: 230844:Got2
uniprot id: A0A6I9LEQ6
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.
messages: In eukaryotes there are cytoplasmic, mitochondrial and chloroplastic isozymes.

230844:Pln
gene id: 230844:Pln
uniprot id: A0A6I9LR22
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phospholamban family.
messages: Endoplasmic reticulum membrane
messages: Homopentamer.
messages: Membrane
messages: Mitochondrion membrane
messages: Reversibly inhibits the activity of ATP2A2 in cardiac sarcoplasmic reticulum by decreasing the apparent affinity of the ATPase for Ca(2+). Modulates the contractility of the heart muscle in response to physiological stimuli via its effects on ATP2A2. Modulates calcium re-uptake during muscle relaxation and plays an important role in calcium homeostasis in the heart muscle. The degree of ATP2A2 inhibition depends on the oligomeric state of PLN.
messages: Sarcoplasmic reticulum membrane

230844:Adcy1
gene id: 230844:Adcy1
uniprot id: A0A6I9L4K9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
messages: Membrane

230844:Ppm1d
gene id: 230844:Ppm1d
uniprot id: A0A6I9LGB4
names: Similarity
messages: Belongs to the PP2C family.

230844:Ip6k3
gene id: 230844:Ip6k3
uniprot id: A0A6I9MGU7
names: Similarity
messages: Belongs to the inositol phosphokinase (IPK) family.

230844:Pomgnt1
gene id: 230844:Pomgnt1
uniprot id: A0A6J0E0B5
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 13 family.
messages: Golgi apparatus membrane
messages: Membrane
messages: Participates in O-mannosyl glycosylation by catalyzing the addition of N-acetylglucosamine to O-linked mannose on glycoproteins. Catalyzes the synthesis of the GlcNAc(beta1-2)Man(alpha1-)O-Ser/Thr moiety on alpha-dystroglycan and other O-mannosylated proteins, providing the necessary basis for the addition of further carbohydrate moieties. Is specific for alpha linked terminal mannose.
messages: The manganese ion interacts primarily with the substrate UDP-N-acetylglucosamine.
messages: The stem domain mediates specific interaction with beta-linked N-acetylglucosamine moieties of O-glycosylated proteins. It also interacts with its product, N-acetyl-beta-D-glucosaminyl-(1->2)-O-alpha-D-mannosylprotein.

230844:Cbl
gene id: 230844:Cbl
uniprot id: A0A6J0CF07
names: Domain
names: Function
messages: E3 ubiquitin-protein ligase which accepts ubiquitin from specific E2 ubiquitin-conjugating enzymes, and transfers it to substrates, generally promoting their degradation by the proteasome.
messages: The N-terminus is composed of the phosphotyrosine binding (PTB) domain, a short linker region and the RING-type zinc finger. The PTB domain, which is also called TKB (tyrosine kinase binding) domain, is composed of three different subdomains: a four-helix bundle (4H), a calcium-binding EF hand and a divergent SH2 domain.

230844:Slc16a5
gene id: 230844:Slc16a5
uniprot id: A0A6I9M717
uniprot id: A0A6J0CLZ9
names: Subcellular Location Annotation
messages: Membrane

230844:Rpl23a
gene id: 230844:Rpl23a
uniprot id: A0A6I9LE17
names: Similarity
messages: Belongs to the universal ribosomal protein uL23 family.

230844:LOC102926553
gene id: 230844:LOC102926553
uniprot id: A0A6I9LXV4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Odr4
gene id: 230844:Odr4
uniprot id: A0A6I9LNS3
names: Function
names: Similarity
messages: Belongs to the ODR-4 family.
messages: May play a role in the trafficking of a subset of G-protein coupled receptors.

230844:Acadvl
gene id: 230844:Acadvl
uniprot id: A0A6I9KYL4
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

230844:LOC102922865
gene id: 230844:LOC102922865
uniprot id: A0A6I9LEU6
names: Subcellular Location Annotation
messages: Membrane

230844:Prlr
gene id: 230844:Prlr
uniprot id: A0A6I9LVU6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type I cytokine receptor family. Type 1 subfamily.
messages: Interacts with SMARCA1. Interacts with NEK3 and VAV2 and this interaction is prolactin-dependent.
messages: Membrane
messages: The WSXWS motif appears to be necessary for proper protein folding and thereby efficient intracellular transport and cell-surface receptor binding.
messages: The box 1 motif is required for JAK interaction and/or activation.
messages: This is a receptor for the anterior pituitary hormone prolactin.

230844:LOC102922403
gene id: 230844:LOC102922403
uniprot id: A0A6J0E5E1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NASP family.
messages: Nucleus

230844:LOC102925339
gene id: 230844:LOC102925339
uniprot id: A0A6I9M9Y2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Clic3
gene id: 230844:Clic3
uniprot id: A0A6I9LRA8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chloride channel CLIC family.
messages: Membrane

230844:Znf397
gene id: 230844:Znf397
uniprot id: A0A6I9LAC5
uniprot id: A0A6J0DGN9
names: Subcellular Location Annotation
messages: Nucleus

230844:LOC102925794
gene id: 230844:LOC102925794
uniprot id: A0A6I9LKD7
names: Function
names: Similarity
messages: Belongs to the IPP isomerase type 1 family.
messages: Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP).

230844:LOC102909390
gene id: 230844:LOC102909390
uniprot id: A0A6I9L8Y4
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

230844:Mtrf1
gene id: 230844:Mtrf1
uniprot id: A0A6I9LSK7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Mitochondrion

230844:Mmp23b
gene id: 230844:Mmp23b
uniprot id: A0A6J0CGL6
names: Caution
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M10A family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Can bind about 5 Ca(2+) ions per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

230844:LOC102903605
gene id: 230844:LOC102903605
uniprot id: A0A6I9L973
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GST superfamily. Mu family.
messages: Cytoplasm

230844:Hbe1
gene id: 230844:Hbe1
uniprot id: A0A6I9LH04
names: Similarity
messages: Belongs to the globin family.

230844:LOC102916577
gene id: 230844:LOC102916577
uniprot id: A0A6I9MF59
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Hoxc5
gene id: 230844:Hoxc5
uniprot id: A0A6I9LDM9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Antp homeobox family.
messages: Nucleus

230844:Atxn1
gene id: 230844:Atxn1
uniprot id: A0A6J0CU26
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATXN1 family.
messages: Nucleus

230844:LOC102912661
gene id: 230844:LOC102912661
uniprot id: A0A6J0CSL3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MHC class II family.
messages: Membrane

230844:C8a
gene id: 230844:C8a
uniprot id: A0A6I9LZ17
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complement C6/C7/C8/C9 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Secreted

230844:Pard3b
gene id: 230844:Pard3b
uniprot id: A0A6I9L1Q1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAR3 family.
messages: Cell junction
messages: Endomembrane system

230844:Grm6
gene id: 230844:Grm6
uniprot id: A0A6I9LYU4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 3 family.
messages: Cell membrane
messages: Membrane

230844:Retn
gene id: 230844:Retn
uniprot id: A0A6I9KYT8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistin/FIZZ family.
messages: Secreted

230844:Bmpr1b
gene id: 230844:Bmpr1b
uniprot id: A0A6J0E4C9
uniprot id: A0A6J0E4D2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
messages: Membrane

230844:Tgfb2
gene id: 230844:Tgfb2
uniprot id: A0A6I9L2X9
uniprot id: A0A6J0EEH8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TGF-beta family.
messages: Homodimer; disulfide-linked.
messages: Precursor of the Latency-associated peptide (LAP) and Transforming growth factor beta-2 (TGF-beta-2) chains, which constitute the regulatory and active subunit of TGF-beta-2, respectively.
messages: extracellular matrix

230844:Rfx3
gene id: 230844:Rfx3
uniprot id: A0A6I9LNX4
names: Subcellular Location Annotation
messages: Nucleus

230844:Mtmr7
gene id: 230844:Mtmr7
uniprot id: A0A6I9KZM4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily.
messages: Cytoplasm

230844:Cdo1
gene id: 230844:Cdo1
uniprot id: A0A6I9L723
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the cysteine dioxygenase family.
messages: Binds 1 Fe cation per subunit.
messages: Catalyzes the oxidation of cysteine to cysteine sulfinic acid with addition of molecular dioxygen.

230844:Pou2f2
gene id: 230844:Pou2f2
uniprot id: A0A6I9M0E9
uniprot id: A0A6I9M261
uniprot id: A0A6I9M631
uniprot id: A0A6J0E1B6
uniprot id: A0A6J0E1C0
uniprot id: A0A6J0E315
uniprot id: A0A6J0E321
uniprot id: A0A6J0E4L4
uniprot id: A0A6J0E6A6
uniprot id: A0A6J0E907
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the POU transcription factor family. Class-2 subfamily.
messages: Nucleus
messages: Transcription factor that binds to the octamer motif (5'-ATTTGCAT-3') and activates the promoters of the genes for some small nuclear RNAs (snRNA) and of genes such as those for histone H2B and immunoglobulins. Modulates transcription transactivation by NR3C1, AR and PGR.

230844:Trappc2l
gene id: 230844:Trappc2l
uniprot id: A0A6I9LZB9
uniprot id: A0A6J0E7G7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAPP small subunits family. Sedlin subfamily.
messages: perinuclear region

230844:Ostc
gene id: 230844:Ostc
uniprot id: A0A6I9KSN1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OSTC family.
messages: Component of the oligosaccharyltransferase (OST) complex.
messages: Membrane
messages: Specific component of the STT3A-containing form of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All subunits are required for a maximal enzyme activity. May be involved in N-glycosylation of APP (amyloid-beta precursor protein). Can modulate gamma-secretase cleavage of APP by enhancing endoprotelysis of PSEN1.

230844:Map1lc3b
gene id: 230844:Map1lc3b
uniprot id: A0A6I9MA09
names: Similarity
messages: Belongs to the ATG8 family.

230844:Gbgt1
gene id: 230844:Gbgt1
uniprot id: A0A6I9MAA3
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 6 family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Membrane

230844:Phf5a
gene id: 230844:Phf5a
uniprot id: A0A6I9LJA4
names: Similarity
messages: Belongs to the PHF5 family.

230844:Esyt3
gene id: 230844:Esyt3
uniprot id: A0A6I9L1F4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the extended synaptotagmin family.
messages: Cell membrane
messages: Endoplasmic reticulum membrane
messages: Membrane

230844:Galnt8
gene id: 230844:Galnt8
uniprot id: A0A6I9M054
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
messages: Golgi apparatus membrane
messages: Membrane

230844:Slc25a33
gene id: 230844:Slc25a33
uniprot id: A0A6J0D825
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

230844:Nxph4
gene id: 230844:Nxph4
uniprot id: A0A6I9L8P4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the neurexophilin family.
messages: May be signaling molecules that resemble neuropeptides.
messages: Secreted

230844:Mboat4
gene id: 230844:Mboat4
uniprot id: A0A6I9L6M2
names: Subcellular Location Annotation
messages: Membrane

230844:Ntrk2
gene id: 230844:Ntrk2
uniprot id: A0A6J0DLI4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. Insulin receptor subfamily.
messages: Membrane

230844:LOC102913127
gene id: 230844:LOC102913127
uniprot id: A0A6I9M7E6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:LOC102926033
gene id: 230844:LOC102926033
uniprot id: A0A6I9LQ04
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome P450 family.
messages: Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.
messages: Endoplasmic reticulum membrane
messages: Microsome membrane

230844:Sesn1
gene id: 230844:Sesn1
uniprot id: A0A6I9LFG0
uniprot id: A0A6I9LVB3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sestrin family.
messages: Cytoplasm

230844:Isy1
gene id: 230844:Isy1
uniprot id: A0A6I9MAK5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ISY1 family.
messages: Nucleus

230844:Slc41a1
gene id: 230844:Slc41a1
uniprot id: A0A6I9M3K5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Membrane

230844:Nfya
gene id: 230844:Nfya
uniprot id: A0A6I9M6N9
uniprot id: A0A6I9MMS5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NFYA/HAP2 subunit family.
messages: Component of the sequence-specific heterotrimeric transcription factor (NF-Y) which specifically recognizes a 5'-CCAAT-3' box motif found in the promoters of its target genes.
messages: Heterotrimer.
messages: Nucleus

230844:Cxxc5
gene id: 230844:Cxxc5
uniprot id: A0A6J0ECP4
names: Subcellular Location Annotation
messages: Cytoplasm

230844:Slc19a3
gene id: 230844:Slc19a3
uniprot id: A0A6I9MAF9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the reduced folate carrier (RFC) transporter (TC 2.A.48) family.
messages: Membrane

230844:Onecut2
gene id: 230844:Onecut2
uniprot id: A0A6J0E1M5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CUT homeobox family.
messages: Nucleus

230844:Rnh1
gene id: 230844:Rnh1
uniprot id: A0A6I9LDL8
uniprot id: A0A6I9LHG8
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Forms high-affinity heterodimers with RNASE1, ANG and RNASE2.
messages: Ribonuclease inhibitor which inhibits RNASE1, RNASE2 and ANG. May play a role in redox homeostasis.

230844:Dgat1
gene id: 230844:Dgat1
uniprot id: A0A6I9LWP4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the membrane-bound acyltransferase family. Sterol o-acyltransferase subfamily.
messages: Endoplasmic reticulum membrane
messages: Homodimer or homotetramer; both forms have similar enzymatic activities.
messages: Membrane

230844:LOC102914706
gene id: 230844:LOC102914706
uniprot id: A0A6I9MAH0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the intercrine beta (chemokine CC) family.
messages: Secreted

230844:Bhmt2
gene id: 230844:Bhmt2
uniprot id: A0A6I9LF94
names: Cofactor
names: Function
names: Subunit
messages: Binds 1 zinc ion per subunit.
messages: Homotetramer.
messages: Involved in the regulation of homocysteine metabolism.

230844:Arhgef6
gene id: 230844:Arhgef6
uniprot id: A0A6I9M9J8
uniprot id: A0A6J0CEZ5
names: Subcellular Location Annotation
messages: lamellipodium

230844:LOC102903297
gene id: 230844:LOC102903297
uniprot id: A0A6I9M8A1
names: Similarity
messages: Belongs to the histone H3 family.

230844:Adh7
gene id: 230844:Adh7
uniprot id: A0A6I9KTB6
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

230844:Hs3st3a1
gene id: 230844:Hs3st3a1
uniprot id: A0A6I9KYM4
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

230844:Polr3k
gene id: 230844:Polr3k
uniprot id: A0A6I9MIC1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family.
messages: Component of the RNA polymerase III (Pol III) complex consisting of 17 subunits.
messages: nucleolus

230844:Gdf10
gene id: 230844:Gdf10
uniprot id: A0A6I9LGD4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TGF-beta family.
messages: Homodimer.
messages: Secreted

230844:Prkd3
gene id: 230844:Prkd3
uniprot id: A0A6I9LUF0
names: Activity Regulation
names: Similarity
names: Subcellular Location Annotation
messages: Activated by DAG and phorbol esters.
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. PKD subfamily.
messages: Cytoplasm
messages: Membrane

230844:Glipr1l2
gene id: 230844:Glipr1l2
uniprot id: A0A6I9L7V3
uniprot id: A0A6J0D5F3
names: Similarity
messages: Belongs to the CRISP family.

230844:Mgat2
gene id: 230844:Mgat2
uniprot id: A0A6I9LMT3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 16 (GT16) protein family.
messages: Golgi apparatus membrane
messages: Membrane

230844:Ephb4
gene id: 230844:Ephb4
uniprot id: A0A6I9KUU6
names: Subcellular Location Annotation
messages: Membrane

230844:Idua
gene id: 230844:Idua
uniprot id: A0A6J0DV59
names: Similarity
messages: Belongs to the glycosyl hydrolase 39 family.

230844:Il17a
gene id: 230844:Il17a
uniprot id: A0A6I9M7H8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IL-17 family.
messages: Secreted

230844:Slc30a6
gene id: 230844:Slc30a6
uniprot id: A0A6I9M6S7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily.
messages: Membrane

230844:Ogt
gene id: 230844:Ogt
uniprot id: A0A6I9LCA2
uniprot id: A0A6J0DQD0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 41 family. O-GlcNAc transferase subfamily.
messages: Cell projection
messages: Mitochondrion membrane

230844:Cdadc1
gene id: 230844:Cdadc1
uniprot id: A0A6I9LQS4
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.

230844:LOC102913936
gene id: 230844:LOC102913936
uniprot id: A0A6I9LED6
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c family.
messages: Binds 1 heme group per subunit.
messages: Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.
messages: Mitochondrion intermembrane space
messages: Plays a role in apoptosis. Suppression of the anti-apoptotic members or activation of the pro-apoptotic members of the Bcl-2 family leads to altered mitochondrial membrane permeability resulting in release of cytochrome c into the cytosol. Binding of cytochrome c to Apaf-1 triggers the activation of caspase-9, which then accelerates apoptosis by activating other caspases.

230844:Cul5
gene id: 230844:Cul5
uniprot id: A0A6I9L3D3
names: Similarity
messages: Belongs to the cullin family.

230844:Ltb4r
gene id: 230844:Ltb4r
uniprot id: A0A6I9M6W9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Belongs to the chemokine-like receptor (CMKLR) family.
messages: Cell membrane
messages: Membrane

230844:Tcf7l2
gene id: 230844:Tcf7l2
uniprot id: A0A6I9L783
uniprot id: A0A6I9L787
uniprot id: A0A6I9L8K1
uniprot id: A0A6I9LFW6
uniprot id: A0A6I9LGH9
uniprot id: A0A6J0DAF8
uniprot id: A0A6J0DAG5
uniprot id: A0A6J0DAI0
uniprot id: A0A6J0DBZ1
uniprot id: A0A6J0DBZ7
uniprot id: A0A6J0DC16
uniprot id: A0A6J0DCA9
uniprot id: A0A6J0DCC4
uniprot id: A0A6J0DCD0
uniprot id: A0A6J0DCP7
uniprot id: A0A6J0DCQ1
uniprot id: A0A6J0DCR9
uniprot id: A0A6J0DHA9
uniprot id: A0A6J0DHB9
uniprot id: A0A6J0DHC7
uniprot id: A0A6J0DHE1
uniprot id: A0A6J0DHE5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TCF/LEF family.
messages: Nucleus

230844:LOC102903239
gene id: 230844:LOC102903239
uniprot id: A0A6I9M980
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:B9d1
gene id: 230844:B9d1
uniprot id: A0A6I9L623
names: Subcellular Location Annotation
messages: cilium basal body

230844:Cry2
gene id: 230844:Cry2
uniprot id: A0A6I9MA72
names: Cofactor
names: Similarity
messages: Belongs to the DNA photolyase class-1 family.
messages: Binds 1 FAD per subunit.

230844:Pdcd4
gene id: 230844:Pdcd4
uniprot id: A0A6I9ME72
names: Similarity
messages: Belongs to the PDCD4 family.

230844:Chac1
gene id: 230844:Chac1
uniprot id: A0A6I9LIB3
names: Function
names: Similarity
messages: Belongs to the gamma-glutamylcyclotransferase family. ChaC subfamily.
messages: Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides.

230844:Ndufb11
gene id: 230844:Ndufb11
uniprot id: A0A6I9M6X0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFB11 subunit family.
messages: Membrane
messages: Mitochondrion inner membrane

230844:Actr1b
gene id: 230844:Actr1b
uniprot id: A0A6I9LZ66
names: Similarity
messages: Belongs to the actin family.

230844:Clec12a
gene id: 230844:Clec12a
uniprot id: A0A6I9MLV9
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

230844:Nkx1-2
gene id: 230844:Nkx1-2
uniprot id: A0A6I9LD06
names: Subcellular Location Annotation
messages: Nucleus

230844:LOC102916717
gene id: 230844:LOC102916717
uniprot id: A0A6J0DCJ8
names: Subcellular Location Annotation
messages: Mitochondrion

230844:Cdc14a
gene id: 230844:Cdc14a
uniprot id: A0A6I9LIV1
uniprot id: A0A6J0DAC0
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class CDC14 subfamily.

230844:Cdc20
gene id: 230844:Cdc20
uniprot id: A0A6I9M0S4
names: Similarity
messages: Belongs to the WD repeat CDC20/Fizzy family.

230844:S1pr1
gene id: 230844:S1pr1
uniprot id: A0A6I9L640
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:F2r
gene id: 230844:F2r
uniprot id: A0A6I9LW80
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Gucy1a1
gene id: 230844:Gucy1a1
uniprot id: A0A6J0DTP7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
messages: Cytoplasm

230844:Tcea2
gene id: 230844:Tcea2
uniprot id: A0A6I9MIC5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TFS-II family.
messages: Necessary for efficient RNA polymerase II transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by S-II allows the resumption of elongation from the new 3'-terminus.
messages: Nucleus

230844:Magt1
gene id: 230844:Magt1
uniprot id: A0A6I9MBL9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OST3/OST6 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

230844:Btg3
gene id: 230844:Btg3
uniprot id: A0A6I9LS89
names: Similarity
messages: Belongs to the BTG family.

230844:Cap2
gene id: 230844:Cap2
uniprot id: A0A6I9KXK9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CAP family.
messages: Cell membrane
messages: Membrane

230844:Lta
gene id: 230844:Lta
uniprot id: A0A6I9MED9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the tumor necrosis factor family.
messages: Cytokine that in its homotrimeric form binds to TNFRSF1A/TNFR1, TNFRSF1B/TNFBR and TNFRSF14/HVEM. In its heterotrimeric form with LTB binds to TNFRSF3/LTBR. Lymphotoxin is produced by lymphocytes and is cytotoxic for a wide range of tumor cells in vitro and in vivo.
messages: Homotrimer, and heterotrimer of either two LTB and one LTA subunits or (less prevalent) two LTA and one LTB subunits. Interacts with TNFRSF14.
messages: Membrane
messages: Secreted

230844:Pik3c2a
gene id: 230844:Pik3c2a
uniprot id: A0A6J0CGZ8
names: Similarity
messages: Belongs to the PI3/PI4-kinase family. Type III PI4K subfamily.

230844:Cd37
gene id: 230844:Cd37
uniprot id: A0A6I9LXF1
uniprot id: A0A6J0DZM7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

230844:Fam131b
gene id: 230844:Fam131b
uniprot id: A0A6I9M7B9
uniprot id: A0A6I9MN51
names: Similarity
messages: Belongs to the FAM131 family.

230844:Tsr1
gene id: 230844:Tsr1
uniprot id: A0A6I9LDU1
names: Subcellular Location Annotation
messages: nucleolus

230844:Nfe2l2
gene id: 230844:Nfe2l2
uniprot id: A0A6I9L6Z7
uniprot id: A0A6J0CLI2
names: Similarity
messages: Belongs to the bZIP family. CNC subfamily.

230844:Kcnh3
gene id: 230844:Kcnh3
uniprot id: A0A6J0D128
uniprot id: A0A6J0D515
names: Subcellular Location Annotation
names: Subunit
messages: Membrane
messages: The potassium channel is probably composed of a homo- or heterotetrameric complex of pore-forming alpha subunits that can associate with modulating beta subunits.

230844:LOC102911175
gene id: 230844:LOC102911175
uniprot id: A0A6I9M8U4
names: Similarity
messages: Belongs to the TCP11 family.

230844:Adcy8
gene id: 230844:Adcy8
uniprot id: A0A6I9LPJ3
uniprot id: A0A6J0DH70
uniprot id: A0A6J0DHL8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
messages: Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.
messages: Membrane

230844:Unc93a
gene id: 230844:Unc93a
uniprot id: A0A6J0D6F1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the unc-93 family.
messages: Membrane

230844:Gmpr
gene id: 230844:Gmpr
uniprot id: A0A6I9KXB8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family. GuaC type 1 subfamily.
messages: Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides.
messages: Homotetramer.

230844:Rpl37a
gene id: 230844:Rpl37a
uniprot id: A0A6I9KWG7
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL43 family.

230844:Pax7
gene id: 230844:Pax7
uniprot id: A0A6I9LR26
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the paired homeobox family.
messages: Nucleus

230844:Sostdc1
gene id: 230844:Sostdc1
uniprot id: A0A6I9LJL2
names: Caution
names: Similarity
messages: Belongs to the sclerostin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

230844:Dlx3
gene id: 230844:Dlx3
uniprot id: A0A6I9L5S0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the distal-less homeobox family.
messages: Nucleus

230844:Mef2c
gene id: 230844:Mef2c
uniprot id: A0A6J0E1F3
names: Subcellular Location Annotation
messages: Nucleus

230844:LOC102924798
gene id: 230844:LOC102924798
uniprot id: A0A6I9M098
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Mpi
gene id: 230844:Mpi
uniprot id: A0A6I9KVC9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the mannose-6-phosphate isomerase type 1 family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in the synthesis of the GDP-mannose and dolichol-phosphate-mannose required for a number of critical mannosyl transfer reactions.

230844:Maf1
gene id: 230844:Maf1
uniprot id: A0A6I9M2V4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MAF1 family.
messages: Element of the TORC1 signaling pathway that acts as a mediator of diverse signals and that represses RNA polymerase III transcription. Inhibits the de novo assembly of TFIIIB onto DNA.
messages: Nucleus

230844:LOC102905140
gene id: 230844:LOC102905140
uniprot id: A0A6I9MKY2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Alkbh6
gene id: 230844:Alkbh6
uniprot id: A0A6J0DJM1
names: Similarity
messages: Belongs to the alkB family.

230844:LOC102912308
gene id: 230844:LOC102912308
uniprot id: A0A6I9MBI1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:LOC102906815
gene id: 230844:LOC102906815
uniprot id: A0A6J0D0B7
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

230844:Jarid2
gene id: 230844:Jarid2
uniprot id: A0A6I9KXB3
uniprot id: A0A6I9L4I7
uniprot id: A0A6J0CUG9
uniprot id: A0A6J0CW60
names: Subcellular Location Annotation
messages: Nucleus

230844:Ric8b
gene id: 230844:Ric8b
uniprot id: A0A6I9LYN2
uniprot id: A0A6I9M3N5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the synembryn family.
messages: Cytoplasm
messages: Guanine nucleotide exchange factor (GEF), which can activate some, but not all, G-alpha proteins by exchanging bound GDP for free GTP.
messages: Interacts with some GDP-bound G alpha proteins. Does not interact with G-alpha proteins when they are in complex with subunits beta and gamma.

230844:Fgf2
gene id: 230844:Fgf2
uniprot id: A0A6I9M7S9
uniprot id: A0A6J0EGQ6
names: Similarity
messages: Belongs to the heparin-binding growth factors family.

230844:LOC102924936
gene id: 230844:LOC102924936
uniprot id: A0A6I9M6N0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GST superfamily. Alpha family.
messages: Cytoplasm

230844:Lcat
gene id: 230844:Lcat
uniprot id: A0A6I9LQX9
names: Similarity
messages: Belongs to the AB hydrolase superfamily. Lipase family.

230844:LOC102919950
gene id: 230844:LOC102919950
uniprot id: A0A6I9M2I4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Lgr5
gene id: 230844:Lgr5
uniprot id: A0A6I9M3T9
names: Subcellular Location Annotation
messages: Membrane

230844:Ckap5
gene id: 230844:Ckap5
uniprot id: A0A6J0DZB2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TOG/XMAP215 family.
messages: kinetochore

230844:Npas1
gene id: 230844:Npas1
uniprot id: A0A6J0EG15
names: Subcellular Location Annotation
messages: Nucleus

230844:Fat2
gene id: 230844:Fat2
uniprot id: A0A6I9LLM6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

230844:Mis12
gene id: 230844:Mis12
uniprot id: A0A6I9M0T4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the mis12 family.
messages: Component of the MIS12 complex composed of MIS12, DSN1, NSL1 and PMF1. Also interacts with KNL1, CBX3, CBX5, NDC80 and ZWINT.
messages: kinetochore

230844:Noc4l
gene id: 230844:Noc4l
uniprot id: A0A6I9LS73
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CBF/MAK21 family.
messages: Nucleus membrane

230844:Atp5f1e
gene id: 230844:Atp5f1e
uniprot id: A0A6I9LB48
names: Function
names: Similarity
messages: Belongs to the eukaryotic ATPase epsilon family.
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(1) domain and of the central stalk which is part of the complex rotary element. Rotation of the central stalk against the surrounding alpha(3)beta(3) subunits leads to hydrolysis of ATP in three separate catalytic sites on the beta subunits.

230844:Mns1
gene id: 230844:Mns1
uniprot id: A0A6J0CYT7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MNS1 family.
messages: Nucleus
messages: cilium axoneme
messages: flagellum axoneme

230844:Bpifb4
gene id: 230844:Bpifb4
uniprot id: A0A6I9M7W0
names: Subcellular Location Annotation
messages: Secreted

230844:LOC102910164
gene id: 230844:LOC102910164
uniprot id: A0A6I9M5P8
names: Function
names: Subunit
messages: In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins.
messages: Interacts with hair keratins.

230844:Pkn1
gene id: 230844:Pkn1
uniprot id: A0A6I9LZ57
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.
messages: Cleavage furrow
messages: Midbody
messages: Nucleus

230844:Cops5
gene id: 230844:Cops5
uniprot id: A0A6I9LBY7
uniprot id: A0A6J0D259
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M67A family. CSN5 subfamily.
messages: synaptic vesicle

230844:Trpc3
gene id: 230844:Trpc3
uniprot id: A0A6I9M996
names: Subcellular Location Annotation
messages: Membrane

230844:Gpr26
gene id: 230844:Gpr26
uniprot id: A0A6I9LGX6
names: Subcellular Location Annotation
messages: Membrane

230844:Tsc22d2
gene id: 230844:Tsc22d2
uniprot id: A0A6I9L6U4
uniprot id: A0A6I9LEG9
names: Similarity
messages: Belongs to the TSC-22/Dip/Bun family.

230844:LOC102918938
gene id: 230844:LOC102918938
uniprot id: A0A6I9KX86
uniprot id: A0A6I9L431
names: Similarity
messages: Belongs to the plakin or cytolinker family.

230844:Hacd1
gene id: 230844:Hacd1
uniprot id: A0A6I9LYA8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the very long-chain fatty acids dehydratase HACD family.
messages: Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

230844:Loxl1
gene id: 230844:Loxl1
uniprot id: A0A6I9L1D3
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lysyl oxidase family.
messages: Mediates the post-translational oxidative deamination of lysine residues on target proteins leading to the formation of deaminated lysine (allysine).
messages: The lysine tyrosylquinone cross-link (LTQ) is generated by condensation of the epsilon-amino group of a lysine with a topaquinone produced by oxidation of tyrosine.
messages: extracellular space

230844:Ctbp2
gene id: 230844:Ctbp2
uniprot id: A0A6I9L4J4
uniprot id: A0A6I9LGW4
uniprot id: A0A6J0DDE8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Nucleus

230844:Npc1l1
gene id: 230844:Npc1l1
uniprot id: A0A6I9L4W6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the patched family.
messages: Membrane

230844:Gtpbp10
gene id: 230844:Gtpbp10
uniprot id: A0A6I9LYZ7
names: Similarity
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.

230844:Washc1
gene id: 230844:Washc1
uniprot id: A0A6J0CUZ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WASH1 family.
messages: Early endosome membrane
messages: Endosome membrane
messages: Recycling endosome membrane

230844:Cfap91
gene id: 230844:Cfap91
uniprot id: A0A6I9LAN4
uniprot id: A0A6J0D9P0
names: Similarity
messages: Belongs to the CFAP91 family.

230844:Aqp4
gene id: 230844:Aqp4
uniprot id: A0A6I9LQ52
uniprot id: A0A6I9LVT9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

230844:Timm17a
gene id: 230844:Timm17a
uniprot id: A0A6I9LEV7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Tim17/Tim22/Tim23 family.
messages: Component of the TIM23 complex at least composed of TIMM23, TIMM17 (TIMM17A or TIMM17B) and TIMM50.
messages: Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane.
messages: Membrane
messages: Mitochondrion inner membrane

230844:Kcnq1
gene id: 230844:Kcnq1
uniprot id: A0A6I9LHQ5
names: Similarity
names: Subcellular Location Annotation
messages: Basolateral cell membrane
messages: Belongs to the potassium channel family. KQT (TC 1.A.1.15) subfamily. Kv7.1/KCNQ1 sub-subfamily.
messages: Cell membrane
messages: Cytoplasmic vesicle membrane
messages: Endoplasmic reticulum
messages: Lateral cell membrane
messages: Membrane
messages: Membrane raft

230844:Tbc1d24
gene id: 230844:Tbc1d24
uniprot id: A0A6J0DED9
uniprot id: A0A6J0DJ48
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasmic vesicle membrane
messages: Interacts with ARF6.
messages: Membrane
messages: Presynapse

230844:B3gnt2
gene id: 230844:B3gnt2
uniprot id: A0A6I9L1B4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane

230844:Adprhl1
gene id: 230844:Adprhl1
uniprot id: A0A6I9LRZ7
names: Similarity
messages: Belongs to the ADP-ribosylglycohydrolase family.

230844:Osbpl11
gene id: 230844:Osbpl11
uniprot id: A0A6I9LBN1
names: Similarity
messages: Belongs to the OSBP family.

230844:Cfap97
gene id: 230844:Cfap97
uniprot id: A0A6I9L380
uniprot id: A0A6J0DEX7
names: Similarity
messages: Belongs to the CFAP97 family.

230844:Myo5b
gene id: 230844:Myo5b
uniprot id: A0A6J0D0H2
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.

230844:Tbx3
gene id: 230844:Tbx3
uniprot id: A0A6I9KTG0
uniprot id: A0A6I9L059
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

230844:Ggt1
gene id: 230844:Ggt1
uniprot id: A0A6I9LHZ8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyltransferase family.
messages: Cleaves the gamma-glutamyl peptide bond of glutathione and glutathione conjugates.
messages: Membrane

230844:Chd1
gene id: 230844:Chd1
uniprot id: A0A6I9LAY8
names: Subcellular Location Annotation
messages: Nucleus

230844:Gatad2b
gene id: 230844:Gatad2b
uniprot id: A0A6I9LBK4
uniprot id: A0A6J0D668
names: Subcellular Location Annotation
messages: Nucleus

230844:LOC102903442
gene id: 230844:LOC102903442
uniprot id: A0A6I9M382
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

230844:Tcea1
gene id: 230844:Tcea1
uniprot id: A0A6I9MCA5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TFS-II family.
messages: Necessary for efficient RNA polymerase II transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by S-II allows the resumption of elongation from the new 3'-terminus.
messages: Nucleus

230844:LOC102921868
gene id: 230844:LOC102921868
uniprot id: A0A6I9LVS6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome c oxidase IV family.
messages: Component of the cytochrome c oxidase (complex IV, CIV), a multisubunit enzyme composed of 14 subunits.
messages: Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.
messages: Membrane
messages: Mitochondrion inner membrane

230844:Tspan10
gene id: 230844:Tspan10
uniprot id: A0A6I9LPG6
names: Subcellular Location Annotation
messages: Membrane

230844:Dynlt4
gene id: 230844:Dynlt4
uniprot id: A0A6J0CIV4
names: Similarity
messages: Belongs to the dynein light chain Tctex-type family.

230844:LOC102915864
gene id: 230844:LOC102915864
uniprot id: A0A6I9MLX3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome P450 family.
messages: Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Microsome membrane

230844:Ptpn1
gene id: 230844:Ptpn1
uniprot id: A0A6I9LY75
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class 1 subfamily.

230844:Izumo1
gene id: 230844:Izumo1
uniprot id: A0A6I9LU07
names: Similarity
messages: Belongs to the Izumo family.

230844:Htr6
gene id: 230844:Htr6
uniprot id: A0A6I9LKX7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

230844:Fth1
gene id: 230844:Fth1
uniprot id: A0A6I9MGW9
names: Function
names: Similarity
messages: Belongs to the ferritin family.
messages: Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation.

230844:Lipt1
gene id: 230844:Lipt1
uniprot id: A0A6I9LPW9
names: Similarity
messages: Belongs to the LplA family.

230844:Aimp2
gene id: 230844:Aimp2
uniprot id: A0A6I9LGY1
uniprot id: A0A6I9LQF9
names: Subcellular Location Annotation
messages: Nucleus
messages: cytosol

230844:Med11
gene id: 230844:Med11
uniprot id: A0A6I9MC83
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 11 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex, which is composed of MED1, MED4, MED6, MED7, MED8, MED9, MED10, MED11, MED12, MED13, MED13L, MED14, MED15, MED16, MED17, MED18, MED19, MED20, MED21, MED22, MED23, MED24, MED25, MED26, MED27, MED29, MED30, MED31, CCNC, CDK8 and CDC2L6/CDK11. The MED12, MED13, CCNC and CDK8 subunits form a distinct module termed the CDK8 module. Mediator containing the CDK8 module is less active than Mediator lacking this module in supporting transcriptional activation. Individual preparations of the Mediator complex lacking one or more distinct subunits have been variously termed ARC, CRSP, DRIP, PC2, SMCC and TRAP.
messages: Nucleus

230844:LOC102904755
gene id: 230844:LOC102904755
uniprot id: A0A6I9M9L4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Ube2d1
gene id: 230844:Ube2d1
uniprot id: A0A6I9LLK0
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

230844:LOC102919819
gene id: 230844:LOC102919819
uniprot id: A0A6J0E3K1
names: Similarity
messages: Belongs to the PRAME family.

230844:Rab3b
gene id: 230844:Rab3b
uniprot id: A0A6I9LIP3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Cell membrane
messages: Protein transport. Probably involved in vesicular traffic.

230844:Cachd1
gene id: 230844:Cachd1
uniprot id: A0A6I9LAI3
names: Similarity
messages: Belongs to the calcium channel subunit alpha-2/delta family.

230844:Mcee
gene id: 230844:Mcee
uniprot id: A0A6I9L3D7
names: Similarity
messages: Belongs to the methylmalonyl-CoA epimerase family.

230844:Ssbp1
gene id: 230844:Ssbp1
uniprot id: A0A6I9M767
names: Subcellular Location Annotation
messages: mitochondrion nucleoid

230844:Arpc5l
gene id: 230844:Arpc5l
uniprot id: A0A6I9M927
names: Function
names: Similarity
messages: Belongs to the ARPC5 family.
messages: Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development.

230844:Nhsl1
gene id: 230844:Nhsl1
uniprot id: A0A6I9LP99
uniprot id: A0A6I9LX29
uniprot id: A0A6J0DW76
uniprot id: A0A6J0DXS1
uniprot id: A0A6J0DZ74
uniprot id: A0A6J0E079
uniprot id: A0A6J0E489
names: Similarity
messages: Belongs to the NHS family.

230844:LOC102926608
gene id: 230844:LOC102926608
uniprot id: A0A6J0CWX3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIB subfamily.
messages: Catalyzes the hydrolysis of ATP coupled with the transport of calcium.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

230844:Extl1
gene id: 230844:Extl1
uniprot id: A0A6I9LDZ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 47 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

230844:Fgf17
gene id: 230844:Fgf17
uniprot id: A0A6I9M424
names: Similarity
messages: Belongs to the heparin-binding growth factors family.

230844:Arfgef1
gene id: 230844:Arfgef1
uniprot id: A0A6I9L8B0
names: Subcellular Location Annotation
messages: Membrane
messages: perinuclear region
messages: trans-Golgi network

230844:Creg2
gene id: 230844:Creg2
uniprot id: A0A6I9LCJ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CREG family.
messages: Secreted

230844:LOC107401572
gene id: 230844:LOC107401572
uniprot id: A0A6J0DGY4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Ap2a2
gene id: 230844:Ap2a2
uniprot id: A0A6I9L504
uniprot id: A0A6I9LHJ8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Adaptor protein complex 2 (AP-2) is a heterotetramer composed of two large adaptins (alpha-type subunit AP2A1 or AP2A2 and beta-type subunit AP2B1), a medium adaptin (mu-type subunit AP2M1) and a small adaptin (sigma-type subunit AP2S1).
messages: Belongs to the adaptor complexes large subunit family.
messages: Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold but is itself unable to bind directly to membrane components. Clathrin-associated adaptor protein (AP) complexes which can bind directly to both the clathrin lattice and to the lipid and protein components of membranes are considered to be the major clathrin adaptors contributing the CCV formation. AP-2 also serves as a cargo receptor to selectively sort the membrane proteins involved in receptor-mediated endocytosis. AP-2 seems to play a role in the recycling of synaptic vesicle membranes from the presynaptic surface. AP-2 recognizes Y-X-X-[FILMV] (Y-X-X-Phi) and [ED]-X-X-X-L-[LI] endocytosis signal motifs within the cytosolic tails of transmembrane cargo molecules. AP-2 may also play a role in maintaining normal post-endocytic trafficking through the ARF6-regulated, non-clathrin pathway. The AP-2 alpha subunit binds polyphosphoinositide-containing lipids, positioning AP-2 on the membrane. The AP-2 alpha subunit acts via its C-terminal appendage domain as a scaffolding platform for endocytic accessory proteins. The AP-2 alpha and AP-2 sigma subunits are thought to contribute to the recognition of the [ED]-X-X-X-L-[LI] motif.
messages: coated pit

230844:Utrn
gene id: 230844:Utrn
uniprot id: A0A6I9LIF4
uniprot id: A0A6I9LTT1
names: Subcellular Location Annotation
messages: cytoskeleton

230844:LOC102904591
gene id: 230844:LOC102904591
uniprot id: A0A6I9M5C6
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIC subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

230844:Atat1
gene id: 230844:Atat1
uniprot id: A0A6I9MEA9
uniprot id: A0A6I9MLS8
uniprot id: A0A6I9MNB8
uniprot id: A0A6J0CS23
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Autoacetylation strongly increases tubulin acetylation.
messages: Belongs to the acetyltransferase ATAT1 family.
messages: Component of the BBSome complex. Interacts with AP2 alpha-adaptins, including AP2A2, but not with AP1 gamma-adaptin (AP1G1/AP1G2); this interaction is required for efficient alpha-tubulin acetylation, hence clathrin-coated pits are sites of microtubule acetylation.
messages: Cytoplasm
messages: Specifically acetylates 'Lys-40' in alpha-tubulin on the lumenal side of microtubules. Promotes microtubule destabilization and accelerates microtubule dynamics; this activity may be independent of acetylation activity. Acetylates alpha-tubulin with a slow enzymatic rate, due to a catalytic site that is not optimized for acetyl transfer. Enters the microtubule through each end and diffuses quickly throughout the lumen of microtubules. Acetylates only long/old microtubules because of its slow acetylation rate since it does not have time to act on dynamically unstable microtubules before the enzyme is released. Required for normal sperm flagellar function. Promotes directional cell locomotion and chemotaxis, through AP2A2-dependent acetylation of alpha-tubulin at clathrin-coated pits that are concentrated at the leading edge of migrating cells. May facilitate primary cilium assembly.
messages: axon
messages: clathrin-coated pit
messages: cytoskeleton
messages: focal adhesion
messages: spindle

230844:Spem1
gene id: 230844:Spem1
uniprot id: A0A6I9KYF1
names: Subcellular Location Annotation
messages: Membrane

230844:Axin1
gene id: 230844:Axin1
uniprot id: A0A6I9L7Z1
uniprot id: A0A6I9LHC4
names: Subcellular Location Annotation
messages: Cytoplasm

230844:LOC102907781
gene id: 230844:LOC102907781
uniprot id: A0A6J0CI35
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the immunoglobulin superfamily. BTN/MOG family.
messages: Membrane

230844:Ngb
gene id: 230844:Ngb
uniprot id: A0A6I9M664
names: Similarity
messages: Belongs to the globin family.

230844:Crx
gene id: 230844:Crx
uniprot id: A0A6I9M6P4
names: Subcellular Location Annotation
messages: Nucleus

230844:Acvr1c
gene id: 230844:Acvr1c
uniprot id: A0A6I9LL32
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
messages: Membrane

230844:Rad18
gene id: 230844:Rad18
uniprot id: A0A6J0CI12
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RAD18 family.
messages: Nucleus

230844:Spsb2
gene id: 230844:Spsb2
uniprot id: A0A6I9M875
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPSB family.
messages: Cytoplasm

230844:Eif4enif1
gene id: 230844:Eif4enif1
uniprot id: A0A6J0D079
names: Subcellular Location Annotation
messages: Cytoplasm

230844:Sema7a
gene id: 230844:Sema7a
uniprot id: A0A6I9KVB6
names: Caution
names: Similarity
messages: Belongs to the semaphorin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

230844:LOC102915827
gene id: 230844:LOC102915827
uniprot id: A0A6I9MF82
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Hrh2
gene id: 230844:Hrh2
uniprot id: A0A6I9LCR6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Pcyox1
gene id: 230844:Pcyox1
uniprot id: A0A6I9LYK7
names: Similarity
messages: Belongs to the prenylcysteine oxidase family.

230844:LOC102923211
gene id: 230844:LOC102923211
uniprot id: A0A6I9LNP1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C1 family.
messages: Lysosome

230844:Smg1
gene id: 230844:Smg1
uniprot id: A0A6I9LND1
names: Similarity
messages: Belongs to the PI3/PI4-kinase family.

230844:Ccdc39
gene id: 230844:Ccdc39
uniprot id: A0A6I9L3Q7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CCDC39 family.
messages: cilium axoneme

230844:Ptk2b
gene id: 230844:Ptk2b
uniprot id: A0A6I9LVD9
uniprot id: A0A6I9M1T2
names: Subcellular Location Annotation
messages: Cell membrane
messages: cell cortex
messages: focal adhesion

230844:Pou3f4
gene id: 230844:Pou3f4
uniprot id: A0A6I9MJ22
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the POU transcription factor family. Class-3 subfamily.
messages: Nucleus

230844:LOC102927806
gene id: 230844:LOC102927806
uniprot id: A0A6I9MKU2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Mthfd1
gene id: 230844:Mthfd1
uniprot id: A0A6I9L4V4
names: Similarity
names: Subunit
messages: Homodimer.
messages: In the C-terminal section; belongs to the formate--tetrahydrofolate ligase family.
messages: In the N-terminal section; belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.

230844:Paqr4
gene id: 230844:Paqr4
uniprot id: A0A6I9MCD0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ADIPOR family.
messages: Membrane

230844:Ca8
gene id: 230844:Ca8
uniprot id: A0A6I9LW56
names: Similarity
messages: Belongs to the alpha-carbonic anhydrase family.

230844:LOC102924901
gene id: 230844:LOC102924901
uniprot id: A0A6I9KUI4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Membrane
messages: tight junction

230844:Mat2b
gene id: 230844:Mat2b
uniprot id: A0A6I9L1L6
uniprot id: A0A6I9L518
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family. MAT2B subfamily.
messages: Heterotrimer; composed of a catalytic MAT2A homodimer that binds one regulatory MAT2B chain. Heterohexamer; composed of a central, catalytic MAT2A homotetramer flanked on either side by a regulatory MAT2B chain. NADP binding increases the affinity for MAT2A.
messages: Regulatory subunit of S-adenosylmethionine synthetase 2, an enzyme that catalyzes the formation of S-adenosylmethionine from methionine and ATP. Regulates MAT2A catalytic activity by changing its kinetic properties, increasing its affinity for L-methionine.

230844:LOC102919906
gene id: 230844:LOC102919906
uniprot id: A0A6I9LM08
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calycin superfamily. Lipocalin family.
messages: Secreted

230844:Rap2a
gene id: 230844:Rap2a
uniprot id: A0A6I9LKU3
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Ras family.
messages: Endosome membrane
messages: Palmitoylated.
messages: Recycling endosome membrane
messages: Small GTP-binding protein which cycles between a GDP-bound inactive and a GTP-bound active form.

230844:Xirp2
gene id: 230844:Xirp2
uniprot id: A0A6I9L3I7
names: Domain
names: Function
names: Similarity
messages: Belongs to the Xin family.
messages: Protects actin filaments from depolymerization.
messages: Xin repeats bind F-actin.

230844:Tnfrsf11b
gene id: 230844:Tnfrsf11b
uniprot id: A0A6I9LGF4
names: Caution
names: Function
names: Subunit
messages: Acts as decoy receptor for TNFSF11/RANKL and thereby neutralizes its function in osteoclastogenesis.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

230844:Hoxd12
gene id: 230844:Hoxd12
uniprot id: A0A6I9L3P6
names: Subcellular Location Annotation
messages: Nucleus

230844:Ttr
gene id: 230844:Ttr
uniprot id: A0A6I9KSB7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transthyretin family.
messages: Homotetramer. Dimer of dimers. In the homotetramer, subunits assemble around a central channel that can accommodate two ligand molecules. Interacts with RBP4.
messages: Secreted
messages: Thyroid hormone-binding protein. Probably transports thyroxine from the bloodstream to the brain.

230844:LOC102906984
gene id: 230844:LOC102906984
uniprot id: A0A6I9M5X9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the immunoglobulin superfamily. BTN/MOG family.
messages: Membrane

230844:Itgb4
gene id: 230844:Itgb4
uniprot id: A0A6I9M733
uniprot id: A0A6J0CIM7
uniprot id: A0A6J0CJ99
uniprot id: A0A6J0CLS4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin beta chain family.
messages: Cell membrane
messages: Membrane

230844:Ackr3
gene id: 230844:Ackr3
uniprot id: A0A6I9M1L5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:LOC102909296
gene id: 230844:LOC102909296
uniprot id: A0A6I9LEI1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic AdoMetDC family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Essential for biosynthesis of the polyamines spermidine and spermine. Promotes maintenance and self-renewal of embryonic stem cells, by maintaining spermine levels.
messages: Heterotetramer of two alpha and two beta chains.

230844:Gcnt4
gene id: 230844:Gcnt4
uniprot id: A0A6J0E303
names: Subcellular Location Annotation
messages: Golgi apparatus membrane
messages: Membrane

230844:Camkmt
gene id: 230844:Camkmt
uniprot id: A0A6I9LXM2
uniprot id: A0A6J0DX64
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

230844:Tyk2
gene id: 230844:Tyk2
uniprot id: A0A6J0E095
names: Similarity
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. JAK subfamily.

230844:Nedd8
gene id: 230844:Nedd8
uniprot id: A0A6I9LUV9
names: Similarity
messages: Belongs to the ubiquitin family.

230844:Lmx1b
gene id: 230844:Lmx1b
uniprot id: A0A6I9M766
names: Subcellular Location Annotation
messages: Nucleus

230844:Acot13
gene id: 230844:Acot13
uniprot id: A0A6I9LHB3
names: Similarity
messages: Belongs to the thioesterase PaaI family.

230844:Tnfrsf19
gene id: 230844:Tnfrsf19
uniprot id: A0A6J0DYC7
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

230844:Prkcq
gene id: 230844:Prkcq
uniprot id: A0A6J0EE15
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.
messages: Cytoplasm

230844:Cd8b
gene id: 230844:Cd8b
uniprot id: A0A6I9M696
names: Subcellular Location Annotation
messages: Membrane

230844:LOC102911651
gene id: 230844:LOC102911651
uniprot id: A0A6I9MAW5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

230844:A2ml1
gene id: 230844:A2ml1
uniprot id: A0A6J0CJ35
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protease inhibitor I39 (alpha-2-macroglobulin) family.
messages: Secreted

230844:LOC102916153
gene id: 230844:LOC102916153
uniprot id: A0A6I9M6Y6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Otub1
gene id: 230844:Otub1
uniprot id: A0A6I9LQN1
names: Similarity
messages: Belongs to the peptidase C65 family.

230844:Mrpl15
gene id: 230844:Mrpl15
uniprot id: A0A6I9MF21
names: Similarity
messages: Belongs to the universal ribosomal protein uL15 family.

230844:Ndor1
gene id: 230844:Ndor1
uniprot id: A0A6I9LL88
uniprot id: A0A6J0DJ47
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NADPH-dependent diflavin oxidoreductase NDOR1 family.
messages: In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
messages: In the N-terminal section; belongs to the flavodoxin family.
messages: Interacts with CIAPIN1; as part of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NADPH-dependent reductase which is a central component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery. Transfers electrons from NADPH via its FAD and FMN prosthetic groups to the [2Fe-2S] cluster of CIAPIN1, another key component of the CIA machinery. In turn, this reduced cluster provides electrons for assembly of cytosolic iron-sulfur cluster proteins. It can also reduce the [2Fe-2S] cluster of CISD1 and activate this protein implicated in Fe/S cluster repair.
messages: perinuclear region

230844:Rps13
gene id: 230844:Rps13
uniprot id: A0A6I9MA35
names: Similarity
messages: Belongs to the universal ribosomal protein uS15 family.

230844:LOC102903913
gene id: 230844:LOC102903913
uniprot id: A0A6I9LMM7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GST superfamily. Mu family.
messages: Cytoplasm

230844:Triqk
gene id: 230844:Triqk
uniprot id: A0A6J0DWL8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRIQK family.
messages: Endoplasmic reticulum membrane
messages: Membrane

230844:LOC102912335
gene id: 230844:LOC102912335
uniprot id: A0A6I9MBQ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Clpx
gene id: 230844:Clpx
uniprot id: A0A6I9LIP6
uniprot id: A0A6J0DEP3
uniprot id: A0A6J0DEW7
names: Similarity
messages: Belongs to the ClpX chaperone family.

230844:Slc30a3
gene id: 230844:Slc30a3
uniprot id: A0A6I9MHY7
uniprot id: A0A6J0CMZ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily.
messages: Membrane

230844:Flt1
gene id: 230844:Flt1
uniprot id: A0A6I9LB00
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.
messages: Cell membrane
messages: Membrane

230844:Cmtm5
gene id: 230844:Cmtm5
uniprot id: A0A6I9M6V1
names: Subcellular Location Annotation
messages: Membrane

230844:Uros
gene id: 230844:Uros
uniprot id: A0A6J0D974
names: Similarity
messages: Belongs to the uroporphyrinogen-III synthase family.

230844:Tafazzin
gene id: 230844:Tafazzin
uniprot id: A0A6I9M8Y1
uniprot id: A0A6J0CE95
uniprot id: A0A6J0CFY6
uniprot id: A0A6J0CGD8
uniprot id: A0A6J0CGE4
uniprot id: A0A6J0CGZ2
uniprot id: A0A6J0CIF3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acyltransferase which is required to remodel newly synthesized phospholipid cardiolipin, a key component of the mitochondrial inner membrane. Required for the initiation of mitophagy. Required to ensure progression of spermatocytes through meiosis.
messages: Associates with multiple protein complexes.
messages: Belongs to the taffazin family.
messages: Mitochondrion inner membrane
messages: Mitochondrion outer membrane

230844:Srrd
gene id: 230844:Srrd
uniprot id: A0A6J0DQ39
names: Similarity
messages: Belongs to the SRR1 family.

230844:LOC102914313
gene id: 230844:LOC102914313
uniprot id: A0A6J0CVA2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Evx1
gene id: 230844:Evx1
uniprot id: A0A6I9LG43
names: Subcellular Location Annotation
messages: Nucleus

230844:LOC102904623
gene id: 230844:LOC102904623
uniprot id: A0A6I9L706
names: Similarity
messages: Belongs to the cytochrome P450 family.

230844:LOC102912006
gene id: 230844:LOC102912006
uniprot id: A0A6I9MJU9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Exoc3l4
gene id: 230844:Exoc3l4
uniprot id: A0A6J0E485
names: Similarity
messages: Belongs to the SEC6 family.

230844:LOC102912309
gene id: 230844:LOC102912309
uniprot id: A0A6I9MF25
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Alax-L subfamily.

230844:Hs3st3b1
gene id: 230844:Hs3st3b1
uniprot id: A0A6I9KYU8
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

230844:LOC102922280
gene id: 230844:LOC102922280
uniprot id: A0A6I9LK83
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

230844:LOC102910947
gene id: 230844:LOC102910947
uniprot id: A0A6I9MG87
names: Subcellular Location Annotation
messages: Membrane

230844:Ptpra
gene id: 230844:Ptpra
uniprot id: A0A6I9LT35
uniprot id: A0A6I9LYH4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Receptor class 4 subfamily.
messages: Cell membrane
messages: Membrane

230844:Gpt2
gene id: 230844:Gpt2
uniprot id: A0A6I9L1V5
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. Alanine aminotransferase subfamily.
messages: Homodimer.

230844:Mrpl52
gene id: 230844:Mrpl52
uniprot id: A0A6I9LQU0
uniprot id: A0A6I9M1A6
uniprot id: A0A6J0E7N0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mL52 family.
messages: Mitochondrion

230844:Slc16a10
gene id: 230844:Slc16a10
uniprot id: A0A6I9LH78
names: Subcellular Location Annotation
messages: Membrane

230844:Adcy2
gene id: 230844:Adcy2
uniprot id: A0A6I9MF69
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
messages: Binds 2 magnesium ions per subunit. Is also active with manganese (in vitro).
messages: Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.
messages: Membrane

230844:Mospd3
gene id: 230844:Mospd3
uniprot id: A0A6I9KUB8
names: Subcellular Location Annotation
messages: Membrane

230844:LOC102925429
gene id: 230844:LOC102925429
uniprot id: A0A6I9L194
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Membrane
messages: tight junction

230844:Tma16
gene id: 230844:Tma16
uniprot id: A0A6J0DZY0
names: Function
names: Similarity
names: Subunit
messages: Associates with pre-60S ribosomal particles.
messages: Belongs to the TMA16 family.
messages: Involved in the biogenesis of the 60S ribosomal subunit in the nucleus.

230844:Cep44
gene id: 230844:Cep44
uniprot id: A0A6I9L076
uniprot id: A0A6I9L3A9
names: Subcellular Location Annotation
messages: Midbody
messages: centriole
messages: spindle pole

230844:LOC102903560
gene id: 230844:LOC102903560
uniprot id: A0A6I9M5A1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HOP2 family.
messages: Nucleus

230844:Eif4a3
gene id: 230844:Eif4a3
uniprot id: A0A6I9M648
names: Similarity
messages: Belongs to the DEAD box helicase family.

230844:Spo11
gene id: 230844:Spo11
uniprot id: A0A6I9LK37
uniprot id: A0A6I9M0C9
names: Similarity
messages: Belongs to the TOP6A family.

230844:Mc2r
gene id: 230844:Mc2r
uniprot id: A0A6I9L1A2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Interacts with MRAP; increasing ligand-sensitivity and generation of cAMP. Interacts with MRAP2; competing with MRAP for binding to MC2R and impairing the binding of corticotropin (ACTH).
messages: Membrane

230844:Faslg
gene id: 230844:Faslg
uniprot id: A0A6I9LAX6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tumor necrosis factor family.
messages: Cell membrane
messages: Cytoplasmic form induces gene transcription inhibition.
messages: Cytoplasmic vesicle lumen
messages: Lysosome lumen
messages: Nucleus
messages: Secreted

230844:Tspan18
gene id: 230844:Tspan18
uniprot id: A0A6I9MJX8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

230844:Acy1
gene id: 230844:Acy1
uniprot id: A0A6I9LFU8
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M20A family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Cytoplasm

230844:Vill
gene id: 230844:Vill
uniprot id: A0A6J0E231
names: Similarity
messages: Belongs to the villin/gelsolin family.

230844:Fxr2
gene id: 230844:Fxr2
uniprot id: A0A6I9KYG4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FMR1 family.
messages: Cytoplasmic ribonucleoprotein granule
messages: Postsynapse
messages: Synapse

230844:Ctnnal1
gene id: 230844:Ctnnal1
uniprot id: A0A6I9LUS2
names: Similarity
messages: Belongs to the vinculin/alpha-catenin family.

230844:Rbm10
gene id: 230844:Rbm10
uniprot id: A0A6I9LVY1
uniprot id: A0A6I9M1L3
uniprot id: A0A6I9M881
uniprot id: A0A6I9MC63
uniprot id: A0A6J0EHP4
names: Subcellular Location Annotation
messages: Nucleus

230844:Itga3
gene id: 230844:Itga3
uniprot id: A0A6I9L294
uniprot id: A0A6J0E751
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin alpha chain family.
messages: Membrane

230844:Septin1
gene id: 230844:Septin1
uniprot id: A0A6I9LH61
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.
messages: Filament-forming cytoskeletal GTPase.
messages: Septins polymerize into heterooligomeric protein complexes that form filaments.

230844:Tspan6
gene id: 230844:Tspan6
uniprot id: A0A6I9LM75
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

230844:Golga5
gene id: 230844:Golga5
uniprot id: A0A6I9MB95
names: Function
names: Subcellular Location Annotation
messages: Golgi apparatus membrane
messages: Involved in maintaining Golgi structure. Stimulates the formation of Golgi stacks and ribbons. Involved in intra-Golgi retrograde transport.

230844:Cant1
gene id: 230844:Cant1
uniprot id: A0A6J0ECS0
names: Similarity
messages: Belongs to the apyrase family.

230844:C12H22orf39
gene id: 230844:C12H22orf39
uniprot id: A0A6I9MCW5
names: Similarity
messages: Belongs to the UPF0545 family.

230844:Cdkal1
gene id: 230844:Cdkal1
uniprot id: A0A6I9L6I7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methylthiotransferase family. CDKAL1 subfamily.
messages: Binds 1 or 2 [4Fe-4S] cluster. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-threonylcarbamoyladenosine (t(6)A), leading to the formation of 2-methylthio-N6-threonylcarbamoyladenosine (ms(2)t(6)A) at position 37 in tRNAs that read codons beginning with adenine.
messages: Endoplasmic reticulum membrane

230844:LOC102915898
gene id: 230844:LOC102915898
uniprot id: A0A6I9LVR6
names: Similarity
messages: Belongs to the SNF7 family.

230844:Vps53
gene id: 230844:Vps53
uniprot id: A0A6I9LDX1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VPS53 family.
messages: Endosome membrane
messages: Membrane
messages: trans-Golgi network membrane

230844:Camta2
gene id: 230844:Camta2
uniprot id: A0A6I9MEY6
uniprot id: A0A6I9MHB8
uniprot id: A0A6J0CIS3
uniprot id: A0A6J0CK05
uniprot id: A0A6J0CKQ0
uniprot id: A0A6J0CL82
uniprot id: A0A6J0CN89
names: Similarity
names: Subunit
messages: Belongs to the CAMTA family.
messages: May interact with calmodulin.

230844:Xpc
gene id: 230844:Xpc
uniprot id: A0A6I9L3K5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the XPC family.
messages: Nucleus

230844:LOC102910872
gene id: 230844:LOC102910872
uniprot id: A0A6I9LNN9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM45 family.
messages: Membrane

230844:Dock11
gene id: 230844:Dock11
uniprot id: A0A6I9MF36
uniprot id: A0A6J0CGY8
uniprot id: A0A6J0CHF4
names: Similarity
messages: Belongs to the DOCK family.

230844:Otx1
gene id: 230844:Otx1
uniprot id: A0A6J0D6T5
names: Subcellular Location Annotation
messages: Nucleus

230844:Fam227a
gene id: 230844:Fam227a
uniprot id: A0A6J0DJK6
names: Similarity
messages: Belongs to the FAM227 family.

230844:Epha4
gene id: 230844:Epha4
uniprot id: A0A6I9KWB7
uniprot id: A0A6J0EEB2
names: Subcellular Location Annotation
messages: Early endosome
messages: Endosome
messages: Membrane

230844:LOC102921413
gene id: 230844:LOC102921413
uniprot id: A0A6I9L2V6
uniprot id: A0A6I9LA57
uniprot id: A0A6I9LA60
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRM TRSPAP family.
messages: Cytoplasm
messages: Involved in the early steps of selenocysteine biosynthesis and tRNA(Sec) charging to the later steps resulting in the cotranslational incorporation of selenocysteine into selenoproteins. Stabilizes the SECISBP2, EEFSEC and tRNA(Sec) complex. May be involved in the methylation of tRNA(Sec). Enhances efficiency of selenoproteins synthesis.
messages: Nucleus

230844:Foxn2
gene id: 230844:Foxn2
uniprot id: A0A6J0DYW7
names: Subcellular Location Annotation
messages: Nucleus

230844:Rnf39
gene id: 230844:Rnf39
uniprot id: A0A6I9MBT5
names: Subcellular Location Annotation
messages: Cytoplasm

230844:Ube2n
gene id: 230844:Ube2n
uniprot id: A0A6I9MHQ8
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

230844:LOC102920339
gene id: 230844:LOC102920339
uniprot id: A0A6I9LRF3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:LOC102910393
gene id: 230844:LOC102910393
uniprot id: A0A6I9LY27
names: Similarity
messages: Belongs to the cytochrome P450 family.

230844:Slc35f6
gene id: 230844:Slc35f6
uniprot id: A0A6I9M8F4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SLC35F solute transporter family.
messages: Interacts with SLC25A5.
messages: May play a role as a nucleotide-sugar transporter.
messages: Membrane
messages: Mitochondrion

230844:LOC102917018
gene id: 230844:LOC102917018
uniprot id: A0A6J0CS88
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Drd1
gene id: 230844:Drd1
uniprot id: A0A6J0D6R0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Dopamine receptor whose activity is mediated by G proteins which activate adenylyl cyclase.
messages: Membrane
messages: dendritic spine

230844:Nfrkb
gene id: 230844:Nfrkb
uniprot id: A0A6I9L4S3
uniprot id: A0A6J0D5X6
uniprot id: A0A6J0D731
uniprot id: A0A6J0D841
uniprot id: A0A6J0DC62
uniprot id: A0A6J0DC66
names: Subcellular Location Annotation
messages: Nucleus

230844:Ythdf2
gene id: 230844:Ythdf2
uniprot id: A0A6I9L2V2
names: Function
names: Similarity
messages: Belongs to the YTHDF family.
messages: Specifically recognizes and binds N6-methyladenosine (m6A)-containing RNAs, and regulates mRNA stability. M6A is a modification present at internal sites of mRNAs and some non-coding RNAs and plays a role in mRNA stability and processing.

230844:Irx4
gene id: 230844:Irx4
uniprot id: A0A6J0E7W0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TALE/IRO homeobox family.
messages: Nucleus

230844:Psd4
gene id: 230844:Psd4
uniprot id: A0A6J0DJ91
names: Subcellular Location Annotation
messages: Membrane
messages: ruffle membrane

230844:Tas2r16
gene id: 230844:Tas2r16
uniprot id: A0A6J0E9R5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor T2R family.
messages: Membrane

230844:Fam229b
gene id: 230844:Fam229b
uniprot id: A0A6J0DQU3
names: Similarity
messages: Belongs to the FAM229 family.

230844:LOC102924940
gene id: 230844:LOC102924940
uniprot id: A0A6I9L617
uniprot id: A0A6I9LIS1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M14 family.
messages: cytosol

230844:Kif5b
gene id: 230844:Kif5b
uniprot id: A0A6I9LA63
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

230844:Eya4
gene id: 230844:Eya4
uniprot id: A0A6I9LBW8
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HAD-like hydrolase superfamily. EYA family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Nucleus

230844:LOC102923421
gene id: 230844:LOC102923421
uniprot id: A0A6I9LNM2
uniprot id: A0A6J0DZB0
uniprot id: A0A6J0E3Y4
names: Similarity
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. SYK/ZAP-70 subfamily.

230844:Eif3i
gene id: 230844:Eif3i
uniprot id: A0A6I9MCQ7
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-3 subunit I family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is composed of 13 subunits: EIF3A, EIF3B, EIF3C, EIF3D, EIF3E, EIF3F, EIF3G, EIF3H, EIF3I, EIF3J, EIF3K, EIF3L and EIF3M. The eIF-3 complex appears to include 3 stable modules: module A is composed of EIF3A, EIF3B, EIF3G and EIF3I; module B is composed of EIF3F, EIF3H, and EIF3M; and module C is composed of EIF3C, EIF3D, EIF3E, EIF3K and EIF3L. EIF3C of module C binds EIF3B of module A and EIF3H of module B, thereby linking the three modules. EIF3J is a labile subunit that binds to the eIF-3 complex via EIF3B. The eIF-3 complex interacts with RPS6KB1 under conditions of nutrient depletion. Mitogenic stimulation leads to binding and activation of a complex composed of MTOR and RPTOR, leading to phosphorylation and release of RPS6KB1 and binding of EIF4B to eIF-3.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation, including cell cycling, differentiation and apoptosis, and uses different modes of RNA stem-loop binding to exert either translational activation or repression.
messages: Cytoplasm
messages: Phosphorylated by TGF-beta type II receptor.

230844:Slc8b1
gene id: 230844:Slc8b1
uniprot id: A0A6J0DD13
names: Subcellular Location Annotation
messages: Membrane

230844:LOC102929119
gene id: 230844:LOC102929119
uniprot id: A0A6J0CSY8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Membrane
messages: tight junction

230844:Man1a1
gene id: 230844:Man1a1
uniprot id: A0A6I9LR18
uniprot id: A0A6J0EA91
names: Similarity
messages: Belongs to the glycosyl hydrolase 47 family.

230844:St14
gene id: 230844:St14
uniprot id: A0A6I9LC77
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S1 family.
messages: Exhibits trypsin-like activity as defined by cleavage of synthetic substrates with Arg or Lys as the P1 site.
messages: Interacts with CDCP1. May interact with TMEFF1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

230844:LOC102921426
gene id: 230844:LOC102921426
uniprot id: A0A6I9MDV0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Dpyd
gene id: 230844:Dpyd
uniprot id: A0A6I9LIW8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the dihydropyrimidine dehydrogenase family.
messages: Binds 4 [4Fe-4S] clusters. Contains approximately 16 iron atoms per subunit.
messages: Involved in pyrimidine base degradation. Catalyzes the reduction of uracil and thymine.

230844:LOC102911767
gene id: 230844:LOC102911767
uniprot id: A0A6I9MGB3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Loxl2
gene id: 230844:Loxl2
uniprot id: A0A6I9LM49
uniprot id: A0A6J0E116
uniprot id: A0A6J0E4W5
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lysyl oxidase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mediates the post-translational oxidative deamination of lysine residues on target proteins leading to the formation of deaminated lysine (allysine).
messages: The lysine tyrosylquinone cross-link (LTQ) is generated by condensation of the epsilon-amino group of a lysine with a topaquinone produced by oxidation of tyrosine.
messages: extracellular space

230844:Myoc
gene id: 230844:Myoc
uniprot id: A0A6I9L8F5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

230844:Scnn1b
gene id: 230844:Scnn1b
uniprot id: A0A6I9LCD7
names: Subcellular Location Annotation
messages: Membrane

230844:LOC102907220
gene id: 230844:LOC102907220
uniprot id: A0A6I9MPW4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:LOC102920649
gene id: 230844:LOC102920649
uniprot id: A0A6I9LST1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:LOC102907854
gene id: 230844:LOC102907854
uniprot id: A0A6I9LSN0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Arap3
gene id: 230844:Arap3
uniprot id: A0A6J0E448
uniprot id: A0A6J0E5U8
names: Subcellular Location Annotation
messages: Cytoplasm

230844:Cdk2ap1
gene id: 230844:Cdk2ap1
uniprot id: A0A6I9KT89
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDK2AP family.
messages: Nucleus

230844:LOC102925646
gene id: 230844:LOC102925646
uniprot id: A0A6I9M0A1
uniprot id: A0A6I9MGJ0
names: Similarity
messages: Belongs to the serpin family.

230844:LOC102911777
gene id: 230844:LOC102911777
uniprot id: A0A6I9LAV8
names: Similarity
messages: Belongs to the COX20 family.

230844:Il1rapl1
gene id: 230844:Il1rapl1
uniprot id: A0A6J0E4M2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the interleukin-1 receptor family.
messages: axon
messages: dendrite

230844:Dnajc18
gene id: 230844:Dnajc18
uniprot id: A0A6I9MBK6
uniprot id: A0A6J0ECP0
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

230844:Cmc2
gene id: 230844:Cmc2
uniprot id: A0A6I9M2C7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CMC family.
messages: Mitochondrion

230844:LOC102903694
gene id: 230844:LOC102903694
uniprot id: A0A6I9MCQ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistin/FIZZ family.
messages: Secreted

230844:Rnps1
gene id: 230844:Rnps1
uniprot id: A0A6I9LHM5
uniprot id: A0A6I9LLB0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the splicing factor SR family.
messages: Found in mRNA splicing-dependent exon junction complexes (EJC). Found in a post-splicing complex with NXF1, RBM8A, UPF1, UPF2, UPF3A, UPF3B and RNPS1. Component of the heterotrimeric ASAP (apoptosis- and splicing-associated protein) and PSAP complexes consisting of RNPS1, SAP18 and either ACIN1 or PNN, respectively; the ASAP and PSAP complexes probably are formed mutually exclusive. Component of the active spliceosome. Associates with polysomes. Interacts with the cleaved p110 isoform of CDC2L1, CSNK2A1, PNN, SART3, SRP54, SRRM1 and TRA2B/SFRS10.
messages: Nucleus speckle

230844:Tmem170a
gene id: 230844:Tmem170a
uniprot id: A0A6I9L6X7
uniprot id: A0A6J0CYU0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM170 family.
messages: Membrane

230844:Ctps1
gene id: 230844:Ctps1
uniprot id: A0A6I9LRW2
names: Function
names: Similarity
messages: Belongs to the CTP synthase family.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.

230844:Celf2
gene id: 230844:Celf2
uniprot id: A0A6J0D0I5
uniprot id: A0A6J0D0J3
uniprot id: A0A6J0D1F0
uniprot id: A0A6J0D1G0
uniprot id: A0A6J0D208
uniprot id: A0A6J0D2S0
uniprot id: A0A6J0D660
uniprot id: A0A6J0D666
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CELF/BRUNOL family.
messages: Cytoplasm
messages: Nucleus

230844:Atp6v1c1
gene id: 230844:Atp6v1c1
uniprot id: A0A6I9LVF3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the V-ATPase C subunit family.
messages: Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment. Subunit C is necessary for the assembly of the catalytic sector of the enzyme and is likely to have a specific function in its catalytic activity.
messages: V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex. The V1 complex consists of three catalytic AB heterodimers that form a heterohexamer, three peripheral stalks each consisting of EG heterodimers, one central rotor including subunits D and F, and the regulatory subunits C and H. The proton translocation complex V0 consists of the proton transport subunit a, a ring of proteolipid subunits c9c'', rotary subunit d, subunits e and f, and two accessory subunits.

230844:LOC102919792
gene id: 230844:LOC102919792
uniprot id: A0A6I9L902
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the leptin family.
messages: Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo-pituitary-adrenal hormones. In the periphery, increases basal metabolism, influences reproductive function, regulates pancreatic beta-cell function and insulin secretion, is pro-angiogenic for endothelial cell and affects innate and adaptive immunity. In the arcuate nucleus of the hypothalamus, activates by depolarization POMC neurons inducing FOS and SOCS3 expression to release anorexigenic peptides and inhibits by hyperpolarization NPY neurons inducing SOCS3 with a consequent reduction on release of orexigenic peptides. In addition to its known satiety inducing effect, has a modulatory role in nutrient absorption. In the intestine, reduces glucose absorption by enterocytes by activating PKC and leading to a sequential activation of p38, PI3K and ERK signaling pathways which exerts an inhibitory effect on glucose absorption. Acts as a growth factor on certain tissues, through the activation of different signaling pathways increases expression of genes involved in cell cycle regulation such as CCND1, via JAK2-STAT3 pathway, or VEGFA, via MAPK1/3 and PI3K-AKT1 pathways. May also play an apoptotic role via JAK2-STAT3 pathway and up-regulation of BIRC5 expression. Pro-angiogenic, has mitogenic activity on vascular endothelial cells and plays a role in matrix remodeling by regulating the expression of matrix metalloproteinases (MMPs) and tissue inhibitors of metalloproteinases (TIMPs). In innate immunity, modulates the activity and function of neutrophils by in…
messages: Secreted

230844:Nr5a1
gene id: 230844:Nr5a1
uniprot id: A0A6J0CH92
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR5 subfamily.
messages: Nucleus

230844:Cnih4
gene id: 230844:Cnih4
uniprot id: A0A6J0CZ15
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cornichon family.
messages: Membrane

230844:Tmem170b
gene id: 230844:Tmem170b
uniprot id: A0A6I9L7N4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM170 family.
messages: Membrane

230844:Parl
gene id: 230844:Parl
uniprot id: A0A6I9LPK0
names: Subcellular Location Annotation
messages: Membrane

230844:Asb1
gene id: 230844:Asb1
uniprot id: A0A6I9MHS9
names: Similarity
messages: Belongs to the ankyrin SOCS box (ASB) family.

230844:LOC102908705
gene id: 230844:LOC102908705
uniprot id: A0A6I9M7R1
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

230844:Tpm2
gene id: 230844:Tpm2
uniprot id: A0A6I9LP30
uniprot id: A0A6J0DVY9
uniprot id: A0A6J0DZX1
uniprot id: A0A6J0E400
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tropomyosin family.
messages: cytoskeleton

230844:Dtx2
gene id: 230844:Dtx2
uniprot id: A0A6I9KUX2
uniprot id: A0A6I9L160
uniprot id: A0A6J0DR44
uniprot id: A0A6J0DRL4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Deltex family.
messages: Cytoplasm

230844:LOC102925434
gene id: 230844:LOC102925434
uniprot id: A0A6I9L1T9
names: Caution
names: Similarity
messages: Belongs to the HHIP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

230844:LOC102916048
gene id: 230844:LOC102916048
uniprot id: A0A6I9MD92
names: Subcellular Location Annotation
messages: Membrane

230844:Gmfb
gene id: 230844:Gmfb
uniprot id: A0A6I9LP10
uniprot id: A0A6J0E7S2
names: Similarity
messages: Belongs to the actin-binding proteins ADF family. GMF subfamily.

230844:Ppp2r5d
gene id: 230844:Ppp2r5d
uniprot id: A0A6I9LV01
uniprot id: A0A6I9M5U3
names: Function
names: Similarity
messages: Belongs to the phosphatase 2A regulatory subunit B56 family.
messages: The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment.

230844:LOC102923488
gene id: 230844:LOC102923488
uniprot id: A0A6I9MMH6
names: Similarity
messages: Belongs to the glycine N-acyltransferase family.

230844:LOC107400504
gene id: 230844:LOC107400504
uniprot id: A0A6J0CWJ7
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

230844:Ltb
gene id: 230844:Ltb
uniprot id: A0A6I9MJJ0
uniprot id: A0A6J0CMS2
names: Similarity
messages: Belongs to the tumor necrosis factor family.

230844:Cspg4
gene id: 230844:Cspg4
uniprot id: A0A6I9KVE1
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

230844:Prickle1
gene id: 230844:Prickle1
uniprot id: A0A6J0CZN1
names: Similarity
messages: Belongs to the prickle / espinas / testin family.

230844:LOC102917532
gene id: 230844:LOC102917532
uniprot id: A0A6I9MKM1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:S100a16
gene id: 230844:S100a16
uniprot id: A0A6J0D656
names: Similarity
messages: Belongs to the S-100 family.

230844:LOC102905770
gene id: 230844:LOC102905770
uniprot id: A0A6I9M4W9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:LOC102914327
gene id: 230844:LOC102914327
uniprot id: A0A6I9MK73
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

230844:C1s
gene id: 230844:C1s
uniprot id: A0A6I9M9P9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

230844:Chrm5
gene id: 230844:Chrm5
uniprot id: A0A6I9M9D1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Muscarinic acetylcholine receptor subfamily.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane
messages: The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. Primary transducing effect is Pi turnover.

230844:B3gnt9
gene id: 230844:B3gnt9
uniprot id: A0A6I9LYM8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane

230844:P2rx7
gene id: 230844:P2rx7
uniprot id: A0A6I9KU01
uniprot id: A0A6J0DAN0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P2X receptor family.
messages: Membrane
messages: Receptor for ATP that acts as a ligand-gated ion channel.

230844:Steap4
gene id: 230844:Steap4
uniprot id: A0A6I9LRN4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STEAP family.
messages: Endosome membrane
messages: Membrane

230844:Esyt2
gene id: 230844:Esyt2
uniprot id: A0A6J0E3M3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the extended synaptotagmin family.
messages: Cell membrane
messages: Endoplasmic reticulum membrane
messages: Membrane

230844:Dgkb
gene id: 230844:Dgkb
uniprot id: A0A6I9LRY3
uniprot id: A0A6I9LSY4
uniprot id: A0A6J0DPU9
uniprot id: A0A6J0DYE1
names: Similarity
messages: Belongs to the eukaryotic diacylglycerol kinase family.

230844:Trarg1
gene id: 230844:Trarg1
uniprot id: A0A6I9L5C8
names: Similarity
messages: Belongs to the CD225/Dispanin family.

230844:Cacnb3
gene id: 230844:Cacnb3
uniprot id: A0A6I9LB95
uniprot id: A0A6J0D081
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calcium channel beta subunit family.
messages: Cytoplasm

230844:Acadm
gene id: 230844:Acadm
uniprot id: A0A6I9LCG5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acyl-CoA dehydrogenase family.
messages: Mitochondrion matrix

230844:Vgll3
gene id: 230844:Vgll3
uniprot id: A0A6I9LSV8
uniprot id: A0A6J0DLD2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vestigial family.
messages: May act as a specific coactivator for the mammalian TEFs.
messages: Nucleus

230844:LOC102906268
gene id: 230844:LOC102906268
uniprot id: A0A6I9L0J1
names: Similarity
messages: Belongs to the CRISP family.

230844:LOC102928599
gene id: 230844:LOC102928599
uniprot id: A0A6I9LG25
names: Subcellular Location Annotation
messages: Membrane

230844:LOC102915785
gene id: 230844:LOC102915785
uniprot id: A0A6J0DMV6
names: Similarity
messages: Belongs to the Arg-specific ADP-ribosyltransferase family.

230844:LOC102928972
gene id: 230844:LOC102928972
uniprot id: A0A6J0CGP9
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

230844:Smo
gene id: 230844:Smo
uniprot id: A0A6I9LMF4
uniprot id: A0A6J0DKE1
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor Fz/Smo family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: cilium

230844:Tec
gene id: 230844:Tec
uniprot id: A0A6J0DL91
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.
messages: Cytoplasm

230844:Ap4e1
gene id: 230844:Ap4e1
uniprot id: A0A6I9LQ51
names: Function
names: Similarity
names: Subunit
messages: Adaptor protein complex 4 (AP-4) is a heterotetramer composed of two large adaptins, a medium adaptin and a small adaptin.
messages: Belongs to the adaptor complexes large subunit family.
messages: Component of the adaptor protein complex 4 (AP-4). Adaptor protein complexes are vesicle coat components involved both in vesicle formation and cargo selection. They control the vesicular transport of proteins in different trafficking pathways. AP-4 forms a non clathrin-associated coat on vesicles departing the trans-Golgi network (TGN) and may be involved in the targeting of proteins from the trans-Golgi network (TGN) to the endosomal-lysosomal system.

230844:Fgg
gene id: 230844:Fgg
uniprot id: A0A6I9LUV1
names: Subcellular Location Annotation
names: Subunit
messages: Heterohexamer; disulfide linked. Contains 2 sets of 3 non-identical chains (alpha, beta and gamma). The 2 heterotrimers are in head to head conformation with the N-termini in a small central domain.
messages: Secreted

230844:Adprh
gene id: 230844:Adprh
uniprot id: A0A6I9L362
names: Similarity
messages: Belongs to the ADP-ribosylglycohydrolase family.

230844:LOC102918874
gene id: 230844:LOC102918874
uniprot id: A0A6I9M850
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Polr2d
gene id: 230844:Polr2d
uniprot id: A0A6I9L7N2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic RPB4 RNA polymerase subunit family.
messages: Nucleus

230844:Ncbp2
gene id: 230844:Ncbp2
uniprot id: A0A6I9LBK5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RRM NCBP2 family.
messages: Component of the cap-binding complex (CBC), which binds co-transcriptionally to the 5' cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing, translation regulation, nonsense-mediated mRNA decay, RNA-mediated gene silencing (RNAi) by microRNAs (miRNAs) and mRNA export. The CBC complex is involved in mRNA export from the nucleus, leading to the recruitment of the mRNA export machinery to the 5' end of mRNA and to mRNA export in a 5' to 3' direction through the nuclear pore. The CBC complex is also involved in mediating U snRNA and intronless mRNAs export from the nucleus. The CBC complex is essential for a pioneer round of mRNA translation, before steady state translation when the CBC complex is replaced by cytoplasmic cap-binding protein eIF4E. The pioneer round of mRNA translation mediated by the CBC complex plays a central role in nonsense-mediated mRNA decay (NMD), NMD only taking place in mRNAs bound to the CBC complex, but not on eIF4E-bound mRNAs. The CBC complex enhances NMD in mRNAs containing at least one exon-junction complex (EJC), promoting the interaction between upf1 and upf2. The CBC complex is also involved in 'failsafe' NMD, which is independent of the EJC complex, while it does not participate in Staufen-mediated mRNA decay (SMD). During cell proliferation, the CBC complex is also involved in microRNAs (miRNAs) biogenesis via its interaction with srrt/ars2, thereby being required for miRNA-mediated RNA interference. The CBC complex also acts as a negative regulator of parn, thereby acting as an inhibitor of mRNA deadenylation. In the CBC complex, ncbp2/cbp20 recognizes and binds capped RNAs (m7GpppG-capped RNA) but requires ncbp1/cbp80 to stabilize the movement of its N-terminal loop and lock the CBC into a high affinity cap-binding state with the cap structure. The conventional cap-binding complex with NCBP2 binds both small nuclear RNA (snRNA) and messenger (mRNA) and is involved in their export from the nucleus.
messages: Component of the nuclear cap-binding complex (CBC), a heterodimer composed of ncbp1/cbp80 and ncbp2/cbp20 that interacts with m7GpppG-capped RNA.
messages: Nucleus

230844:Ears2
gene id: 230844:Ears2
uniprot id: A0A6I9LPN4
names: Function
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).

230844:LOC102915548
gene id: 230844:LOC102915548
uniprot id: A0A6I9LH70
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Required for normal vault structure. Vaults are multi-subunit structures that may act as scaffolds for proteins involved in signal transduction. Vaults may also play a role in nucleo-cytoplasmic transport. Down-regulates IFNG-mediated STAT1 signaling and subsequent activation of JAK. Down-regulates SRC activity and signaling through MAP kinases.

230844:Gprasp2
gene id: 230844:Gprasp2
uniprot id: A0A6J0CY04
names: Similarity
messages: Belongs to the GPRASP family.

230844:Cenpc
gene id: 230844:Cenpc
uniprot id: A0A6I9LJC3
names: Similarity
messages: Belongs to the CENP-C/MIF2 family.

230844:LOC102919251
gene id: 230844:LOC102919251
uniprot id: A0A6I9L3J7
names: Similarity
messages: Belongs to the TCP10 family.

230844:Slc51a
gene id: 230844:Slc51a
uniprot id: A0A6I9L0S8
names: Subcellular Location Annotation
messages: Membrane

230844:LOC102905412
gene id: 230844:LOC102905412
uniprot id: A0A6I9KSM8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome P450 family.
messages: Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.
messages: Endoplasmic reticulum membrane
messages: Microsome membrane

230844:Slc4a4
gene id: 230844:Slc4a4
uniprot id: A0A6J0EGD1
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Basolateral cell membrane
messages: Belongs to the anion exchanger (TC 2.A.31) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Lateral cell membrane
messages: Membrane

230844:Tmem150b
gene id: 230844:Tmem150b
uniprot id: A0A6I9M9I2
names: Subcellular Location Annotation
messages: Membrane

230844:Fut1
gene id: 230844:Fut1
uniprot id: A0A6I9LDY2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 11 family.
messages: Golgi stack membrane
messages: Membrane

230844:Fgf11
gene id: 230844:Fgf11
uniprot id: A0A6I9L924
uniprot id: A0A6J0CXY1
names: Similarity
messages: Belongs to the heparin-binding growth factors family.

230844:Cstf2
gene id: 230844:Cstf2
uniprot id: A0A6I9LQ13
uniprot id: A0A6J0DYK5
uniprot id: A0A6J0E161
uniprot id: A0A6J0E528
names: Subcellular Location Annotation
messages: Nucleus

230844:Kcnk15
gene id: 230844:Kcnk15
uniprot id: A0A6I9L3I4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
messages: Membrane

230844:Ppp1r10
gene id: 230844:Ppp1r10
uniprot id: A0A6I9MLS7
uniprot id: A0A6J0CSE0
names: Function
names: Subcellular Location Annotation
messages: Nucleus
messages: Scaffold protein which mediates the formation of the PTW/PP1 phosphatase complex by providing a binding platform to each component of the complex. The PTW/PP1 phosphatase complex plays a role in the control of chromatin structure and cell cycle progression during the transition from mitosis into interphase. Mediates interaction of WDR82 and PPP1CA. Inhibitor of PPP1CA and PPP1CC phosphatase activities. Has inhibitory activity on PPP1CA only when phosphorylated. Binds to mRNA, single-stranded DNA (ssDNA), poly(A) and poly(G) homopolymers.

230844:Wdr46
gene id: 230844:Wdr46
uniprot id: A0A6I9MCV0
names: Subcellular Location Annotation
messages: nucleolus

230844:Copg2
gene id: 230844:Copg2
uniprot id: A0A6I9LAK9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the COPG family.
messages: COPI-coated vesicle membrane
messages: Cytoplasm
messages: Golgi apparatus membrane
messages: Membrane
messages: Oligomeric complex.
messages: The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.

230844:Lztfl1
gene id: 230844:Lztfl1
uniprot id: A0A6I9M5S0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LZTFL1 family.
messages: Cytoplasm
messages: Regulates ciliary localization of the BBSome complex. Together with the BBSome complex, controls SMO ciliary trafficking and contributes to the sonic hedgehog (SHH) pathway regulation. May play a role in neurite outgrowth. May have tumor suppressor function.
messages: Self-associates. Interacts with BBS9; the interaction mediates the association of LZTL1 with the BBsome complex and regulates BBSome ciliary trafficking.

230844:Nfs1
gene id: 230844:Nfs1
uniprot id: A0A6I9M2M2
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.

230844:Camsap2
gene id: 230844:Camsap2
uniprot id: A0A6I9LEU1
uniprot id: A0A6I9LQ18
uniprot id: A0A6J0DKN7
uniprot id: A0A6J0DUH4
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CAMSAP1 family.
messages: The CKK domain binds microtubules.
messages: cytoskeleton

230844:Eme2
gene id: 230844:Eme2
uniprot id: A0A6I9KV94
uniprot id: A0A6J0DZP3
names: Similarity
messages: Belongs to the EME1/MMS4 family.

230844:LOC102926342
gene id: 230844:LOC102926342
uniprot id: A0A6I9LV26
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

230844:Opa1
gene id: 230844:Opa1
uniprot id: A0A6I9L0E1
uniprot id: A0A6I9L0P7
uniprot id: A0A6I9L7Y0
uniprot id: A0A6I9LBI2
names: Subcellular Location Annotation
messages: Membrane
messages: Mitochondrion inner membrane
messages: Mitochondrion membrane

230844:Ppil1
gene id: 230844:Ppil1
uniprot id: A0A6J0DMK6
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

230844:Taldo1
gene id: 230844:Taldo1
uniprot id: A0A6I9LDI1
names: Function
names: Similarity
messages: Belongs to the transaldolase family. Type 1 subfamily.
messages: Catalyzes the rate-limiting step of the non-oxidative phase in the pentose phosphate pathway. Catalyzes the reversible conversion of sedheptulose-7-phosphate and D-glyceraldehyde 3-phosphate into erythrose-4-phosphate and beta-D-fructose 6-phosphate.

230844:Hprt1
gene id: 230844:Hprt1
uniprot id: A0A6I9LEK6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Converts guanine to guanosine monophosphate, and hypoxanthine to inosine monophosphate. Transfers the 5-phosphoribosyl group from 5-phosphoribosylpyrophosphate onto the purine. Plays a central role in the generation of purine nucleotides through the purine salvage pathway.
messages: Cytoplasm
messages: Homotetramer.

230844:Siah1
gene id: 230844:Siah1
uniprot id: A0A6I9KVQ1
names: Domain
names: Function
names: Similarity
messages: Belongs to the SINA (Seven in absentia) family.
messages: E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.
messages: The RING-type zinc finger domain is essential for ubiquitin ligase activity.
messages: The SBD domain (substrate-binding domain) mediates the interaction with substrate proteins. It is related to the TRAF family.

230844:Agxt
gene id: 230844:Agxt
uniprot id: A0A6I9LXA4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.
messages: Peroxisome

230844:Amer2
gene id: 230844:Amer2
uniprot id: A0A6J0E4U0
names: Similarity
messages: Belongs to the Amer family.

230844:LOC102905872
gene id: 230844:LOC102905872
uniprot id: A0A6J0D8I1
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

230844:Rragb
gene id: 230844:Rragb
uniprot id: A0A6I9M253
uniprot id: A0A6I9MDQ5
uniprot id: A0A6J0CNH2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTR/RAG GTP-binding protein family.
messages: Cytoplasm
messages: Guanine nucleotide-binding protein that plays a crucial role in the cellular response to amino acid availability through regulation of the mTORC1 signaling cascade.
messages: Lysosome
messages: Lysosome membrane

230844:Egfr
gene id: 230844:Egfr
uniprot id: A0A6J0CNX9
uniprot id: A0A6J0CR14
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. EGF receptor subfamily.
messages: Membrane

230844:Fbp2
gene id: 230844:Fbp2
uniprot id: A0A6I9LMF7
names: Similarity
messages: Belongs to the FBPase class 1 family.

230844:Ache
gene id: 230844:Ache
uniprot id: A0A6J0DWB1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type-B carboxylesterase/lipase family.
messages: Secreted

230844:LOC102928996
gene id: 230844:LOC102928996
uniprot id: A0A6J0D493
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CCDC47 family.
messages: Rough endoplasmic reticulum membrane

230844:LOC102913851
gene id: 230844:LOC102913851
uniprot id: A0A6I9LU33
names: Similarity
messages: Belongs to the aldo/keto reductase family.

230844:LOC107400081
gene id: 230844:LOC107400081
uniprot id: A0A6J0EC58
names: Subcellular Location Annotation
messages: Secreted

230844:Homer2
gene id: 230844:Homer2
uniprot id: A0A6I9KY51
uniprot id: A0A6I9L0Z8
names: Subcellular Location Annotation
messages: Cytoplasm

230844:Rragc
gene id: 230844:Rragc
uniprot id: A0A6I9ME81
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTR/RAG GTP-binding protein family.
messages: Cytoplasm
messages: Guanine nucleotide-binding protein that plays a crucial role in the cellular response to amino acid availability through regulation of the mTORC1 signaling cascade.
messages: Lysosome
messages: Lysosome membrane

230844:Rpl4
gene id: 230844:Rpl4
uniprot id: A0A6I9L1J4
names: Similarity
messages: Belongs to the universal ribosomal protein uL4 family.

230844:LOC102903171
gene id: 230844:LOC102903171
uniprot id: A0A6I9L8X6
names: Similarity
messages: Belongs to the beta/gamma-crystallin family.

230844:C9H10orf53
gene id: 230844:C9H10orf53
uniprot id: A0A6I9L458
names: Similarity
messages: Belongs to the UPF0728 family.

230844:Adam32
gene id: 230844:Adam32
uniprot id: A0A6I9LVN3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

230844:LOC102902931
gene id: 230844:LOC102902931
uniprot id: A0A6I9LQM8
names: Similarity
messages: Belongs to the TTC39 family.

230844:LOC102915090
gene id: 230844:LOC102915090
uniprot id: A0A6I9LS43
names: Subcellular Location Annotation
messages: Nucleus

230844:Dusp8
gene id: 230844:Dusp8
uniprot id: A0A6I9LHK3
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.

230844:Rab4a
gene id: 230844:Rab4a
uniprot id: A0A6J0ECF3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Cell membrane
messages: Protein transport.

230844:Pla2g3
gene id: 230844:Pla2g3
uniprot id: A0A6I9L4M8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phospholipase A2 family.
messages: Secreted

230844:Melk
gene id: 230844:Melk
uniprot id: A0A6J0E431
names: Similarity
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. SNF1 subfamily.

230844:Hs3st6
gene id: 230844:Hs3st6
uniprot id: A0A6I9L836
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

230844:Nim1k
gene id: 230844:Nim1k
uniprot id: A0A6I9LXY3
names: Similarity
messages: Belongs to the protein kinase superfamily.

230844:LOC102909343
gene id: 230844:LOC102909343
uniprot id: A0A6I9MA11
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the COA3 family.
messages: Component of 250-400 kDa complexes called cytochrome oxidase assembly intermediates or COA complexes.
messages: Core component of the MITRAC (mitochondrial translation regulation assembly intermediate of cytochrome c oxidase complex) complex, that regulates cytochrome c oxidase assembly. MITRAC complexes regulate both translation of mitochondrial encoded components and assembly of nuclear-encoded components imported in mitochondrion. Required for efficient translation of MT-CO1 and mitochondrial respiratory chain complex IV assembly.
messages: Membrane
messages: Required for assembly of cytochrome c oxidase (complex IV).

230844:Dtwd2
gene id: 230844:Dtwd2
uniprot id: A0A6I9MCI3
names: Similarity
messages: Belongs to the TDD superfamily. DTWD2 family.

230844:Gabrb3
gene id: 230844:Gabrb3
uniprot id: A0A6I9MIA2
uniprot id: A0A6I9MKG9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

230844:Atp6v1b2
gene id: 230844:Atp6v1b2
uniprot id: A0A6I9M8W2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Apical cell membrane
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Non-catalytic subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment.
messages: V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex. The V1 complex consists of three catalytic AB heterodimers that form a heterohexamer, three peripheral stalks each consisting of EG heterodimers, one central rotor including subunits D and F, and the regulatory subunits C and H. The proton translocation complex V0 consists of the proton transport subunit a, a ring of proteolipid subunits c9c'', rotary subunit d, subunits e and f, and the accessory subunits.

230844:Mars2
gene id: 230844:Mars2
uniprot id: A0A6I9L8Q1
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

230844:LOC102911169
gene id: 230844:LOC102911169
uniprot id: A0A6I9MDF4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Uxs1
gene id: 230844:Uxs1
uniprot id: A0A6I9M014
uniprot id: A0A6I9MG84
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. UDP-glucuronic acid decarboxylase subfamily.
messages: Golgi stack membrane
messages: Membrane

230844:Rrp7a
gene id: 230844:Rrp7a
uniprot id: A0A6I9LAI9
names: Similarity
messages: Belongs to the RRP7 family.

230844:Erap1
gene id: 230844:Erap1
uniprot id: A0A6I9LIR2
uniprot id: A0A6J0DFE2
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M1 family.
messages: Binds 1 zinc ion per subunit.

230844:Ldb2
gene id: 230844:Ldb2
uniprot id: A0A6I9LD87
uniprot id: A0A6I9LNJ9
uniprot id: A0A6I9LSX4
uniprot id: A0A6J0DS63
names: Similarity
messages: Belongs to the LDB family.

230844:Dkk3
gene id: 230844:Dkk3
uniprot id: A0A6I9L7J8
uniprot id: A0A6J0DDA3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dickkopf family.
messages: Secreted

230844:Osbpl8
gene id: 230844:Osbpl8
uniprot id: A0A6J0D261
names: Similarity
messages: Belongs to the OSBP family.

230844:LOC102910670
gene id: 230844:LOC102910670
uniprot id: A0A6I9MH67
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:LOC102907369
gene id: 230844:LOC102907369
uniprot id: A0A6J0E595
names: Similarity
messages: Belongs to the SEC2 family.

230844:Itgb1
gene id: 230844:Itgb1
uniprot id: A0A6I9LGQ1
uniprot id: A0A6I9LP17
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin beta chain family.
messages: Cell membrane
messages: Membrane

230844:LOC107401224
gene id: 230844:LOC107401224
uniprot id: A0A6J0D8R7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAM24 family.
messages: Secreted

230844:Ccnl2
gene id: 230844:Ccnl2
uniprot id: A0A6I9MAP4
uniprot id: A0A6I9MDY4
uniprot id: A0A6J0CFN9
names: Similarity
messages: Belongs to the cyclin family.

230844:Npffr2
gene id: 230844:Npffr2
uniprot id: A0A6I9MCL5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for NPAF (A-18-F-amide) and NPFF (F-8-F-amide) neuropeptides, also known as morphine-modulating peptides. Can also be activated by a variety of naturally occurring or synthetic FMRF-amide like ligands. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system.

230844:Pdia4
gene id: 230844:Pdia4
uniprot id: A0A6I9MAN5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the protein disulfide isomerase family.
messages: Endoplasmic reticulum lumen
messages: Part of a large chaperone multiprotein complex.

230844:LOC102912864
gene id: 230844:LOC102912864
uniprot id: A0A6I9MI26
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

230844:Itm2a
gene id: 230844:Itm2a
uniprot id: A0A6I9M4M7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ITM2 family.
messages: Membrane

230844:Ltbp3
gene id: 230844:Ltbp3
uniprot id: A0A6I9LKG3
uniprot id: A0A6I9LQG0
uniprot id: A0A6J0DFP4
uniprot id: A0A6J0DHZ1
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

230844:Abca12
gene id: 230844:Abca12
uniprot id: A0A6I9KWH9
uniprot id: A0A6I9L6F6
names: Subcellular Location Annotation
messages: Membrane

230844:LOC102921127
gene id: 230844:LOC102921127
uniprot id: A0A6I9MLB5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Fbln5
gene id: 230844:Fbln5
uniprot id: A0A6I9MB87
uniprot id: A0A6J0E8L7
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

230844:Tsen15
gene id: 230844:Tsen15
uniprot id: A0A6I9LJX3
names: Similarity
messages: Belongs to the SEN15 family.

230844:LOC102907924
gene id: 230844:LOC102907924
uniprot id: A0A6I9MNR2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Atraid
gene id: 230844:Atraid
uniprot id: A0A6I9MEZ8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

230844:Ern1
gene id: 230844:Ern1
uniprot id: A0A6I9L2B4
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

230844:Pepd
gene id: 230844:Pepd
uniprot id: A0A6I9LJG9
names: Similarity
messages: Belongs to the peptidase M24B family.

230844:Fam161a
gene id: 230844:Fam161a
uniprot id: A0A6I9L1A9
uniprot id: A0A6I9L8K4
names: Similarity
messages: Belongs to the FAM161 family.

230844:Chgb
gene id: 230844:Chgb
uniprot id: A0A6I9LSZ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromogranin/secretogranin protein family.
messages: Secreted

230844:Prpsap1
gene id: 230844:Prpsap1
uniprot id: A0A6I9MBC1
names: Similarity
messages: Belongs to the ribose-phosphate pyrophosphokinase family.

230844:Prdm6
gene id: 230844:Prdm6
uniprot id: A0A6I9LSJ5
names: Subcellular Location Annotation
messages: Nucleus

230844:LOC102923305
gene id: 230844:LOC102923305
uniprot id: A0A6I9M891
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Inka2
gene id: 230844:Inka2
uniprot id: A0A6I9M2H3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the INKA family.
messages: Nucleus

230844:Tyms
gene id: 230844:Tyms
uniprot id: A0A6I9LU08
names: Similarity
messages: Belongs to the thymidylate synthase family.

230844:Rab3d
gene id: 230844:Rab3d
uniprot id: A0A6I9LPX0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Cell membrane
messages: Protein transport. Probably involved in vesicular traffic.

230844:C3H12orf57
gene id: 230844:C3H12orf57
uniprot id: A0A6I9LX51
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0456 family.
messages: Cytoplasm

230844:Itgal
gene id: 230844:Itgal
uniprot id: A0A6I9L5U5
uniprot id: A0A6I9LDB3
uniprot id: A0A6J0D8J0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin alpha chain family.
messages: Membrane

230844:Get3
gene id: 230844:Get3
uniprot id: A0A6I9M9Q6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATPase required for the post-translational delivery of tail-anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. Subsequently, the homodimer reverts towards the open dimer state, lowering its affinity for the membrane-bound receptor, and returning it to the cytosol to initiate a new round of targeting.
messages: Belongs to the arsA ATPase family.
messages: Cytoplasm
messages: Endoplasmic reticulum
messages: Homodimer. Component of a transmembrane domain recognition complex (TRC). Interacts with SERP1 and SEC61B. Interacts with WRB.
messages: nucleolus

230844:Dclre1b
gene id: 230844:Dclre1b
uniprot id: A0A6I9LKS5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA repair metallo-beta-lactamase (DRMBL) family.
messages: Nucleus

230844:Cd44
gene id: 230844:Cd44
uniprot id: A0A6I9LH68
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: microvillus

230844:Strn4
gene id: 230844:Strn4
uniprot id: A0A6J0EFZ4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat striatin family.
messages: Binds calmodulin in a calcium dependent manner. May function as scaffolding or signaling protein.
messages: Membrane

230844:Rnf167
gene id: 230844:Rnf167
uniprot id: A0A6J0CN94
names: Subcellular Location Annotation
messages: Membrane

230844:Gins3
gene id: 230844:Gins3
uniprot id: A0A6I9LIT8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GINS3/PSF3 family.
messages: Chromosome
messages: Component of the GINS complex.
messages: Nucleus
messages: The GINS complex plays an essential role in the initiation of DNA replication.

230844:LOC102903986
gene id: 230844:LOC102903986
uniprot id: A0A6I9M784
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Hdac11
gene id: 230844:Hdac11
uniprot id: A0A6I9KWZ6
names: Subcellular Location Annotation
messages: Nucleus

230844:Yipf2
gene id: 230844:Yipf2
uniprot id: A0A6I9LZB0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YIP1 family.
messages: Endosome membrane
messages: Golgi apparatus membrane
messages: Late endosome membrane
messages: Membrane
messages: cis-Golgi network membrane
messages: trans-Golgi network membrane

230844:Borcs8
gene id: 230844:Borcs8
uniprot id: A0A6J0CMQ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BORCS8 family.
messages: Lysosome membrane
messages: Membrane

230844:LOC102922301
gene id: 230844:LOC102922301
uniprot id: A0A6I9MB37
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

230844:Vgll4
gene id: 230844:Vgll4
uniprot id: A0A6I9L7E8
uniprot id: A0A6I9LGP9
names: Function
names: Similarity
messages: Belongs to the vestigial family.
messages: May act as a specific coactivator for the mammalian TEFs.

230844:Psma6
gene id: 230844:Psma6
uniprot id: A0A6I9M018
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1A family.
messages: Cytoplasm
messages: Nucleus
messages: The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits.

230844:Suv39h2
gene id: 230844:Suv39h2
uniprot id: A0A6J0DZK9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. Suvar3-9 subfamily.
messages: Nucleus
messages: centromere

230844:LOC102916882
gene id: 230844:LOC102916882
uniprot id: A0A6I9M7L6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

230844:Adcy3
gene id: 230844:Adcy3
uniprot id: A0A6I9LMY0
uniprot id: A0A6J0DHX2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
messages: Binds 2 magnesium ions per subunit. Is also active with manganese (in vitro).
messages: Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.
messages: Membrane

230844:Chrna2
gene id: 230844:Chrna2
uniprot id: A0A6I9LRA4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

230844:LOC107399359
gene id: 230844:LOC107399359
uniprot id: A0A6J0CGU2
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

230844:Ctla4
gene id: 230844:Ctla4
uniprot id: A0A6I9L186
uniprot id: A0A6I9L916
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: Inhibitory receptor acting as a major negative regulator of T-cell responses. The affinity of CTLA4 for its natural B7 family ligands, CD80 and CD86, is considerably stronger than the affinity of their cognate stimulatory coreceptor CD28.
messages: Membrane

230844:L3hypdh
gene id: 230844:L3hypdh
uniprot id: A0A6I9MB12
names: Similarity
messages: Belongs to the proline racemase family.

230844:Mrpl14
gene id: 230844:Mrpl14
uniprot id: A0A6I9LJF6
names: Similarity
messages: Belongs to the universal ribosomal protein uL14 family.

230844:Ngfr
gene id: 230844:Ngfr
uniprot id: A0A6I9L2P0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

230844:Wnt8a
gene id: 230844:Wnt8a
uniprot id: A0A6I9LJ29
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

230844:Timm13
gene id: 230844:Timm13
uniprot id: A0A6I9L809
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the small Tim family.
messages: Heterohexamer.
messages: Mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space.
messages: Mitochondrion inner membrane
messages: The twin CX3C motif contains 4 conserved Cys residues that form 2 disulfide bonds in the mitochondrial intermembrane space.

230844:Cln5
gene id: 230844:Cln5
uniprot id: A0A6I9L7P9
names: Similarity
messages: Belongs to the CLN5 family.

230844:LOC102921878
gene id: 230844:LOC102921878
uniprot id: A0A6I9LPP3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protease inhibitor I39 (alpha-2-macroglobulin) family.
messages: Secreted

230844:Cenpj
gene id: 230844:Cenpj
uniprot id: A0A6I9MAZ1
names: Similarity
messages: Belongs to the TCP10 family.

230844:Tp53
gene id: 230844:Tp53
uniprot id: A0A6I9KYG7
uniprot id: A0A6J0CXZ4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression.
messages: Belongs to the p53 family.
messages: Binds 1 zinc ion per subunit.
messages: Binds DNA as a homotetramer.
messages: Cytoplasm
messages: Endoplasmic reticulum
messages: Mitochondrion matrix
messages: Nucleus
messages: PML body

230844:Marcksl1
gene id: 230844:Marcksl1
uniprot id: A0A6I9MFH4
names: Similarity
messages: Belongs to the MARCKS family.

230844:LOC102920232
gene id: 230844:LOC102920232
uniprot id: A0A6I9LEQ8
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Ribosomal protein P0 is the functional equivalent of E.coli protein L10.

230844:LOC102905643
gene id: 230844:LOC102905643
uniprot id: A0A6I9MA02
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tubulin family.
messages: Tubulin is the major constituent of microtubules. The gamma chain is found at microtubule organizing centers (MTOC) such as the spindle poles or the centrosome. Pericentriolar matrix component that regulates alpha/beta chain minus-end nucleation, centrosome duplication and spindle formation.
messages: centrosome

230844:Tbk1
gene id: 230844:Tbk1
uniprot id: A0A6I9KY93
names: Subcellular Location Annotation
messages: Cytoplasm

230844:Aph1a
gene id: 230844:Aph1a
uniprot id: A0A6I9LQB1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the APH-1 family.
messages: Component of the gamma-secretase complex.
messages: Membrane
messages: Potential subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral proteins such as Notch receptors.

230844:Ube2k
gene id: 230844:Ube2k
uniprot id: A0A6I9L0L2
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

230844:LOC102927545
gene id: 230844:LOC102927545
uniprot id: A0A6I9LY24
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

230844:Znf18
gene id: 230844:Znf18
uniprot id: A0A6I9L5Y9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the krueppel C2H2-type zinc-finger protein family.
messages: Nucleus

230844:LOC102919113
gene id: 230844:LOC102919113
uniprot id: A0A6I9LN75
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Higd1c
gene id: 230844:Higd1c
uniprot id: A0A6J0DT18
names: Subcellular Location Annotation
messages: Mitochondrion inner membrane

230844:Mllt3
gene id: 230844:Mllt3
uniprot id: A0A6I9L2U3
names: Subcellular Location Annotation
messages: Nucleus

230844:Ndufb2
gene id: 230844:Ndufb2
uniprot id: A0A6I9LU54
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFB2 subunit family.
messages: Complex I is composed of 45 different subunits.
messages: Mitochondrion inner membrane

230844:Dhx15
gene id: 230844:Dhx15
uniprot id: A0A6I9LB96
names: Similarity
messages: Belongs to the DEAD box helicase family. DEAH subfamily. DDX15/PRP43 sub-subfamily.

230844:Oaz2
gene id: 230844:Oaz2
uniprot id: A0A6I9GZR0
names: Similarity
messages: Belongs to the ODC antizyme family.

230844:Rad51d
gene id: 230844:Rad51d
uniprot id: A0A6I9M4B5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family. RAD51 subfamily.
messages: Involved in the homologous recombination repair (HRR) pathway of double-stranded DNA breaks arising during DNA replication or induced by DNA-damaging agents.
messages: Nucleus

230844:LOC102909076
gene id: 230844:LOC102909076
uniprot id: A0A6I9MP22
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Nr1h4
gene id: 230844:Nr1h4
uniprot id: A0A6I9L9V1
uniprot id: A0A6I9LJQ7
uniprot id: A0A6I9LNI7
uniprot id: A0A6J0DE00
uniprot id: A0A6J0DG27
uniprot id: A0A6J0DGJ2
uniprot id: A0A6J0DLM0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR1 subfamily.
messages: Nucleus

230844:LOC102917796
gene id: 230844:LOC102917796
uniprot id: A0A6I9M6E6
names: Similarity
messages: Belongs to the CBP3 family.

230844:Fmo2
gene id: 230844:Fmo2
uniprot id: A0A6I9L176
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FMO family.
messages: Endoplasmic reticulum membrane
messages: Microsome membrane

230844:Higd1a
gene id: 230844:Higd1a
uniprot id: A0A6J0DPQ4
names: Subcellular Location Annotation
messages: Mitochondrion inner membrane

230844:Kcne4
gene id: 230844:Kcne4
uniprot id: A0A6J0EAF5
names: Similarity
messages: Belongs to the potassium channel KCNE family.

230844:Dmrtc2
gene id: 230844:Dmrtc2
uniprot id: A0A6J0E332
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DMRT family.
messages: Nucleus

230844:LOC102921418
gene id: 230844:LOC102921418
uniprot id: A0A6I9L4C8
uniprot id: A0A6I9LBQ6
uniprot id: A0A6I9LBR7
uniprot id: A0A6J0D703
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SCAMP family.
messages: Belongs to the protein kinase superfamily.
messages: Membrane

230844:Gipr
gene id: 230844:Gipr
uniprot id: A0A6I9MGN5
names: Subcellular Location Annotation
messages: Membrane

230844:Fxyd6
gene id: 230844:Fxyd6
uniprot id: A0A6I9M3X0
uniprot id: A0A6J0E963
names: Similarity
messages: Belongs to the FXYD family.

230844:Adam8
gene id: 230844:Adam8
uniprot id: A0A6I9LP61
uniprot id: A0A6J0E030
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

230844:LOC102916253
gene id: 230844:LOC102916253
uniprot id: A0A6I9M2H2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

230844:Atpaf2
gene id: 230844:Atpaf2
uniprot id: A0A6I9L9H6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP12 family.
messages: Mitochondrion

230844:Stx11
gene id: 230844:Stx11
uniprot id: A0A6J0DUJ0
names: Similarity
messages: Belongs to the syntaxin family.

230844:Optc
gene id: 230844:Optc
uniprot id: A0A6J0CKG4
names: Similarity
messages: Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class III subfamily.

230844:Traf4
gene id: 230844:Traf4
uniprot id: A0A6I9LEA0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TNF receptor-associated factor family.
messages: Cytoplasm

230844:LOC102907786
gene id: 230844:LOC102907786
uniprot id: A0A6J0CJ64
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Rtel1
gene id: 230844:Rtel1
uniprot id: A0A6I9MG12
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent DNA helicase implicated in telomere-length regulation, DNA repair and the maintenance of genomic stability. Acts as an anti-recombinase to counteract toxic recombination and limit crossover during meiosis. Regulates meiotic recombination and crossover homeostasis by physically dissociating strand invasion events and thereby promotes noncrossover repair by meiotic synthesis dependent strand annealing (SDSA) as well as disassembly of D loop recombination intermediates. Also disassembles T loops and prevents telomere fragility by counteracting telomeric G4-DNA structures, which together ensure the dynamics and stability of the telomere.
messages: Belongs to the helicase family. RAD3/XPD subfamily.
messages: Interacts with TERF1. Interacts (via PIP-box) with PCNA; the interaction is direct and essential for suppressing telomere fragility. Interacts with MMS19; the interaction mediates the association of RTEL1 with the cytosolic iron-sulfur protein assembly (CIA) complex.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

230844:Cds1
gene id: 230844:Cds1
uniprot id: A0A6I9L9S4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Catalyzes the conversion of phosphatidic acid (PA) to CDP-diacylglycerol (CDP-DAG), an essential intermediate in the synthesis of phosphatidylglycerol, cardiolipin and phosphatidylinositol.
messages: Membrane

230844:Hdac7
gene id: 230844:Hdac7
uniprot id: A0A6I9L7P3
uniprot id: A0A6J0CZS1
uniprot id: A0A6J0D5B7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone deacetylase family. HD type 2 subfamily.
messages: Nucleus
messages: Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.

230844:Rnf13
gene id: 230844:Rnf13
uniprot id: A0A6I9L5L9
names: Subcellular Location Annotation
messages: Membrane

230844:Mterf1
gene id: 230844:Mterf1
uniprot id: A0A6J0DYS0
names: Similarity
messages: Belongs to the mTERF family.

230844:Rrp8
gene id: 230844:Rrp8
uniprot id: A0A6I9M915
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methyltransferase superfamily. RRP8 family.
messages: Component of the eNoSC complex.
messages: Essential component of the eNoSC (energy-dependent nucleolar silencing) complex, a complex that mediates silencing of rDNA in response to intracellular energy status and acts by recruiting histone-modifying enzymes. The eNoSC complex is able to sense the energy status of cell: upon glucose starvation, elevation of NAD(+)/NADP(+) ratio activates SIRT1, leading to histone H3 deacetylation followed by dimethylation of H3 at 'Lys-9' (H3K9me2) by SUV39H1 and the formation of silent chromatin in the rDNA locus. In the complex, RRP8 binds to H3K9me2 and probably acts as a methyltransferase.
messages: nucleolus

230844:Ints10
gene id: 230844:Ints10
uniprot id: A0A6I9M3C2
uniprot id: A0A6J0E545
uniprot id: A0A6J0E6Z4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Integrator subunit 10 family.
messages: Nucleus

230844:Septin8
gene id: 230844:Septin8
uniprot id: A0A6I9M4C0
uniprot id: A0A6I9MBH0
uniprot id: A0A6I9MFK8
uniprot id: A0A6J0CNW4
uniprot id: A0A6J0CP39
uniprot id: A0A6J0CQD8
uniprot id: A0A6J0CR68
uniprot id: A0A6J0CR73
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.
messages: Filament-forming cytoskeletal GTPase.
messages: Septins polymerize into heterooligomeric protein complexes that form filaments.

230844:Serpina4
gene id: 230844:Serpina4
uniprot id: A0A6I9MBB3
names: Similarity
messages: Belongs to the serpin family.

230844:LOC102924797
gene id: 230844:LOC102924797
uniprot id: A0A6I9LUG5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

230844:Fam183a
gene id: 230844:Fam183a
uniprot id: A0A6I9LLS9
names: Similarity
messages: Belongs to the CFAP144 family.

230844:Cbfa2t3
gene id: 230844:Cbfa2t3
uniprot id: A0A6I9M4K3
uniprot id: A0A6J0E465
uniprot id: A0A6J0E7H0
names: Similarity
messages: Belongs to the CBFA2T family.

230844:Atp6ap2
gene id: 230844:Atp6ap2
uniprot id: A0A6I9LCV9
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Lysosome membrane
messages: Membrane
messages: autophagosome membrane
messages: clathrin-coated vesicle membrane
messages: dendritic spine membrane
messages: synaptic vesicle membrane

230844:Rap2b
gene id: 230844:Rap2b
uniprot id: A0A6I9KWX1
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Ras family.
messages: Endosome membrane
messages: Palmitoylated.
messages: Recycling endosome membrane
messages: Small GTP-binding protein which cycles between a GDP-bound inactive and a GTP-bound active form.

230844:C16H6orf58
gene id: 230844:C16H6orf58
uniprot id: A0A6I9M1R8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LEG1 family.
messages: Secreted

230844:Neu3
gene id: 230844:Neu3
uniprot id: A0A6J0DJY3
names: Similarity
messages: Belongs to the glycosyl hydrolase 33 family.

230844:Arpc3
gene id: 230844:Arpc3
uniprot id: A0A6I9L012
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ARPC3 family.
messages: Component of the Arp2/3 complex.
messages: Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.
messages: cytoskeleton

230844:Mrgpre
gene id: 230844:Mrgpre
uniprot id: A0A6J0D9Z9
names: Subcellular Location Annotation
messages: Membrane

230844:LOC102911051
gene id: 230844:LOC102911051
uniprot id: A0A6I9MC34
names: Similarity
messages: Belongs to the ATP:guanido phosphotransferase family.

230844:Adh5
gene id: 230844:Adh5
uniprot id: A0A6I9MAT9
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.

230844:Ggta1
gene id: 230844:Ggta1
uniprot id: A0A6J0CPN8
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 6 family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Membrane

230844:Oip5
gene id: 230844:Oip5
uniprot id: A0A6I9M7W8
names: Function
names: Subcellular Location Annotation
messages: Nucleus
messages: Required for recruitment of CENPA to centromeres and normal chromosome segregation during mitosis.
messages: centromere

230844:Slc35b1
gene id: 230844:Slc35b1
uniprot id: A0A6I9L5R5
uniprot id: A0A6J0ECP7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleotide-sugar transporter family. SLC35B subfamily.
messages: Membrane

230844:Cdc42
gene id: 230844:Cdc42
uniprot id: A0A6I9LDH6
uniprot id: A0A6I9LLQ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rho family. CDC42 subfamily.
messages: Cell membrane
messages: Membrane
messages: Midbody
messages: Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state.

230844:Zscan29
gene id: 230844:Zscan29
uniprot id: A0A6I9M7Y8
names: Function
names: Subcellular Location Annotation
messages: May be involved in transcriptional regulation.
messages: Nucleus

230844:LOC102921232
gene id: 230844:LOC102921232
uniprot id: A0A6I9ME97
uniprot id: A0A6I9MLS1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MHC class I family.
messages: Membrane

230844:Sar1a
gene id: 230844:Sar1a
uniprot id: A0A6I9KXA8
names: Similarity
messages: Belongs to the small GTPase superfamily. SAR1 family.

230844:Hrh1
gene id: 230844:Hrh1
uniprot id: A0A6J0CNF1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Vwc2l
gene id: 230844:Vwc2l
uniprot id: A0A6I9M223
names: Subcellular Location Annotation
messages: Synapse

230844:Rrad
gene id: 230844:Rrad
uniprot id: A0A6I9LKB6
names: Similarity
messages: Belongs to the small GTPase superfamily. RGK family.

230844:Dusp26
gene id: 230844:Dusp26
uniprot id: A0A6I9L6K2
names: Function
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.
messages: Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate.

230844:Ndufa12
gene id: 230844:Ndufa12
uniprot id: A0A6I9M191
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFA12 subunit family.
messages: Complex I is composed of 45 different subunits.
messages: Mitochondrion inner membrane

230844:Tpm1
gene id: 230844:Tpm1
uniprot id: A0A6I9LM34
uniprot id: A0A6J0DCU3
uniprot id: A0A6J0DCU8
uniprot id: A0A6J0DEJ9
uniprot id: A0A6J0DEK2
uniprot id: A0A6J0DEK6
uniprot id: A0A6J0DES2
uniprot id: A0A6J0DES7
uniprot id: A0A6J0DF69
uniprot id: A0A6J0DF75
uniprot id: A0A6J0DJZ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tropomyosin family.
messages: cytoskeleton

230844:Tom1l1
gene id: 230844:Tom1l1
uniprot id: A0A6I9KW47
names: Similarity
messages: Belongs to the TOM1 family.

230844:Ercc2
gene id: 230844:Ercc2
uniprot id: A0A6I9ME92
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the helicase family. RAD3/XPD subfamily.
messages: Nucleus

230844:Entpd1
gene id: 230844:Entpd1
uniprot id: A0A6J0E463
names: Similarity
messages: Belongs to the GDA1/CD39 NTPase family.

230844:Meox2
gene id: 230844:Meox2
uniprot id: A0A6I9LHP9
names: Subcellular Location Annotation
messages: Nucleus

230844:LOC102909735
gene id: 230844:LOC102909735
uniprot id: A0A6I9LT99
uniprot id: A0A6J0E5K0
names: Similarity
messages: Belongs to the aldo/keto reductase family.

230844:Smpd2
gene id: 230844:Smpd2
uniprot id: A0A6I9LVD8
names: Similarity
messages: Belongs to the neutral sphingomyelinase family.

230844:Nsun5
gene id: 230844:Nsun5
uniprot id: A0A6I9KUG4
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.

230844:Senp8
gene id: 230844:Senp8
uniprot id: A0A6I9L1B5
names: Similarity
messages: Belongs to the peptidase C48 family.

230844:Ldaf1
gene id: 230844:Ldaf1
uniprot id: A0A6I9M174
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LDAF1 family.
messages: Endoplasmic reticulum membrane
messages: Lipid droplet
messages: Membrane

230844:Rbfox1
gene id: 230844:Rbfox1
uniprot id: A0A6I9LL38
uniprot id: A0A6I9LTD2
uniprot id: A0A6I9LU79
uniprot id: A0A6I9LYN5
uniprot id: A0A6J0DRZ2
uniprot id: A0A6J0DRZ7
uniprot id: A0A6J0DTH1
uniprot id: A0A6J0DTH6
uniprot id: A0A6J0DUP0
uniprot id: A0A6J0DUP4
uniprot id: A0A6J0DVF4
uniprot id: A0A6J0DVG0
uniprot id: A0A6J0DVG5
uniprot id: A0A6J0E075
uniprot id: A0A6J0E081
names: Function
names: Subcellular Location Annotation
messages: Nucleus
messages: RNA-binding protein that regulates alternative splicing events.

230844:Skap1
gene id: 230844:Skap1
uniprot id: A0A6J0EBX3
names: Similarity
messages: Belongs to the SKAP family.

230844:Slc39a4
gene id: 230844:Slc39a4
uniprot id: A0A6I9M4G5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZIP transporter (TC 2.A.5) family.
messages: Membrane

230844:Pank4
gene id: 230844:Pank4
uniprot id: A0A6I9M443
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activity is strongly promoted by Co(2+), Ni(2+), Mg(2+) and Mn(2+). Activity is inhibited by EDTA.
messages: Belongs to the type II pantothenate kinase family.
messages: Cytoplasm
messages: Homodimer. Interacts with PKM.
messages: In the N-terminal section; belongs to the type II pantothenate kinase family.
messages: Phosphatase which shows a preference for 4'-phosphopantetheine and its oxidatively damaged forms (sulfonate or S-sulfonate), providing strong indirect evidence that the phosphatase activity pre-empts damage in the coenzyme A (CoA) pathway. Hydrolyzing excess 4'-phosphopantetheine could constitute a directed overflow mechanism to prevent its oxidation to the S-sulfonate, sulfonate, or other forms. Hydrolyzing 4'-phosphopantetheine sulfonate or S-sulfonate would forestall their conversion to inactive forms of CoA and acyl carrier protein. May play a role in the physiological regulation of CoA intracellular levels.

230844:Slc24a3
gene id: 230844:Slc24a3
uniprot id: A0A6I9LTW4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. SLC24A subfamily.
messages: Membrane

230844:LOC102914672
gene id: 230844:LOC102914672
uniprot id: A0A6I9M929
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

230844:Cep20
gene id: 230844:Cep20
uniprot id: A0A6I9LRR7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CEP43 family.
messages: centriole
messages: cilium basal body

230844:LOC102908165
gene id: 230844:LOC102908165
uniprot id: A0A6I9LSX1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PET117 family.
messages: Mitochondrion

230844:Sgo1
gene id: 230844:Sgo1
uniprot id: A0A6I9MEK9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the shugoshin family.
messages: centromere

230844:Evc
gene id: 230844:Evc
uniprot id: A0A6J0DX92
names: Subcellular Location Annotation
messages: Membrane
messages: cilium basal body
messages: cilium membrane

230844:LOC102924974
gene id: 230844:LOC102924974
uniprot id: A0A6I9LZI4
uniprot id: A0A6J0DT84
uniprot id: A0A6J0DUL4
uniprot id: A0A6J0E1G6
names: Similarity
messages: Belongs to the interleukin-1 receptor family.

230844:LOC102920960
gene id: 230844:LOC102920960
uniprot id: A0A6I9LN77
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:LOC102903502
gene id: 230844:LOC102903502
uniprot id: A0A6J0CV41
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Piezo1
gene id: 230844:Piezo1
uniprot id: A0A6I9LNT4
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PIEZO (TC 1.A.75) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

230844:Entr1
gene id: 230844:Entr1
uniprot id: A0A6I9LC07
uniprot id: A0A6I9LDQ6
uniprot id: A0A6I9LLY9
uniprot id: A0A6J0DJA1
names: Similarity
messages: Belongs to the ENTR1 family.

230844:Mfsd5
gene id: 230844:Mfsd5
uniprot id: A0A6I9LDR2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily.
messages: Cell membrane
messages: Mediates high-affinity intracellular uptake of the rare oligo-element molybdenum.
messages: Membrane

230844:LOC102909272
gene id: 230844:LOC102909272
uniprot id: A0A6I9MI64
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AMY1 family.
messages: Nucleus

230844:Rmnd1
gene id: 230844:Rmnd1
uniprot id: A0A6I9LJF3
names: Similarity
messages: Belongs to the RMD1/sif2 family.

230844:LOC102913983
gene id: 230844:LOC102913983
uniprot id: A0A6I9L3Q5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

230844:Cert1
gene id: 230844:Cert1
uniprot id: A0A6I9LKZ9
uniprot id: A0A6I9LW84
names: Subcellular Location Annotation
messages: Endoplasmic reticulum
messages: Golgi apparatus

230844:LOC102923770
gene id: 230844:LOC102923770
uniprot id: A0A6I9M5V6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2B family.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

230844:Oprl1
gene id: 230844:Oprl1
uniprot id: A0A6I9MD50
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Cytoplasmic vesicle
messages: G-protein coupled opioid receptor that functions as receptor for the endogenous neuropeptide nociceptin. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. Signaling via G proteins mediates inhibition of adenylate cyclase activity and calcium channel activity. Arrestins modulate signaling via G proteins and mediate the activation of alternative signaling pathways that lead to the activation of MAP kinases. Plays a role in modulating nociception and the perception of pain. Plays a role in the regulation of locomotor activity by the neuropeptide nociceptin.
messages: Membrane
messages: Vesicle

230844:LOC102925478
gene id: 230844:LOC102925478
uniprot id: A0A6I9M8K0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Scn7a
gene id: 230844:Scn7a
uniprot id: A0A6J0D934
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium channel (TC 1.A.1.10) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient.
messages: Membrane

230844:Prorp
gene id: 230844:Prorp
uniprot id: A0A6J0DUW1
names: Similarity
messages: Belongs to the PPR family. P subfamily.

230844:Itm2c
gene id: 230844:Itm2c
uniprot id: A0A6I9LXW5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ITM2 family.
messages: Membrane

230844:Ddx59
gene id: 230844:Ddx59
uniprot id: A0A6I9LGH3
names: Similarity
messages: Belongs to the DEAD box helicase family. DDX59 subfamily.

230844:LOC102911327
gene id: 230844:LOC102911327
uniprot id: A0A6I9M9B1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Cxxc4
gene id: 230844:Cxxc4
uniprot id: A0A6J0D5Z0
names: Subcellular Location Annotation
messages: Cytoplasm

230844:LOC102911202
gene id: 230844:LOC102911202
uniprot id: A0A6I9LWG8
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

230844:Psmc5
gene id: 230844:Psmc5
uniprot id: A0A6I9KSX0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAA ATPase family.
messages: Nucleus

230844:Hat1
gene id: 230844:Hat1
uniprot id: A0A6I9L3C2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAT1 family.
messages: Catalytic subunit of the type B histone acetyltransferase (HAT) complex, composed of RBBP7 and HAT1. Interacts with histones H4 and H2A.
messages: Histone acetyltransferase that plays a role in different biological processes including cell cycle progression, glucose metabolism, histone production or DNA damage repair. Coordinates histone production and acetylation via H4 promoter binding. Acetylates histone H4 at 'Lys-5' (H4K5ac) and 'Lys-12' (H4K12ac) and, to a lesser extent, histone H2A at 'Lys-5' (H2AK5ac).

230844:Gng5
gene id: 230844:Gng5
uniprot id: A0A6J0DVP6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G protein gamma family.
messages: Cell membrane
messages: G proteins are composed of 3 units; alpha, beta and gamma.
messages: Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.
messages: Membrane

230844:Fam162a
gene id: 230844:Fam162a
uniprot id: A0A6I9L2D1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0389 family.
messages: Membrane

230844:Laptm5
gene id: 230844:Laptm5
uniprot id: A0A6I9LDS6
names: Similarity
messages: Belongs to the LAPTM4/LAPTM5 transporter family.

230844:Hoxa3
gene id: 230844:Hoxa3
uniprot id: A0A6J0DK19
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Antp homeobox family.
messages: Nucleus

230844:Fhip1a
gene id: 230844:Fhip1a
uniprot id: A0A6I9M0B3
names: Similarity
messages: Belongs to the FHIP family.

230844:Alkbh1
gene id: 230844:Alkbh1
uniprot id: A0A6I9M673
names: Cofactor
messages: Binds 1 Fe(2+) ion per subunit.

230844:LOC102926245
gene id: 230844:LOC102926245
uniprot id: A0A6I9M5A5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:B3gnt6
gene id: 230844:B3gnt6
uniprot id: A0A6I9LIP8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane

230844:Sdhaf4
gene id: 230844:Sdhaf4
uniprot id: A0A6I9LVJ0
names: Similarity
messages: Belongs to the SDHAF4 family.

230844:Slc37a4
gene id: 230844:Slc37a4
uniprot id: A0A6I9M4Z7
uniprot id: A0A6J0CJ97
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Organophosphate:Pi antiporter (OPA) (TC 2.A.1.4) family.
messages: Membrane

230844:Ganab
gene id: 230844:Ganab
uniprot id: A0A6I9MA95
uniprot id: A0A6I9MH89
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.

230844:Spin1
gene id: 230844:Spin1
uniprot id: A0A6I9L5E7
names: Similarity
messages: Belongs to the SPIN/STSY family.

230844:Ndufaf7
gene id: 230844:Ndufaf7
uniprot id: A0A6I9M2T5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Arginine methyltransferase involved in the assembly or stability of mitochondrial NADH:ubiquinone oxidoreductase complex (complex I).
messages: Belongs to the NDUFAF7 family.
messages: Mitochondrion

230844:Timm10
gene id: 230844:Timm10
uniprot id: A0A6I9M913
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the small Tim family.
messages: Heterohexamer.
messages: Mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space.
messages: Mitochondrion inner membrane
messages: The twin CX3C motif contains 4 conserved Cys residues that form 2 disulfide bonds in the mitochondrial intermembrane space.

230844:Actn2
gene id: 230844:Actn2
uniprot id: A0A6I9LJ81
names: Similarity
messages: Belongs to the alpha-actinin family.

230844:Arl6ip5
gene id: 230844:Arl6ip5
uniprot id: A0A6I9L767
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRA1 family.
messages: Membrane

230844:LOC102913766
gene id: 230844:LOC102913766
uniprot id: A0A6I9M9V0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cornichon family.
messages: Membrane

230844:Hesx1
gene id: 230844:Hesx1
uniprot id: A0A6J0DKJ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ANF homeobox family.
messages: Nucleus

230844:LOC102908034
gene id: 230844:LOC102908034
uniprot id: A0A6J0DGY6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFB11 subunit family.
messages: Membrane
messages: Mitochondrion inner membrane

230844:Ss18
gene id: 230844:Ss18
uniprot id: A0A6I9LG41
uniprot id: A0A6I9LVU5
uniprot id: A0A6J0DW39
names: Similarity
messages: Belongs to the SS18 family.

230844:Pkia
gene id: 230844:Pkia
uniprot id: A0A6I9LFA6
names: Function
names: Similarity
messages: Belongs to the PKI family.
messages: Extremely potent competitive inhibitor of cAMP-dependent protein kinase activity, this protein interacts with the catalytic subunit of the enzyme after the cAMP-induced dissociation of its regulatory chains.

230844:LOC102920945
gene id: 230844:LOC102920945
uniprot id: A0A6I9LDG6
names: Similarity
messages: Belongs to the peptidase C1 family.

230844:Foxa1
gene id: 230844:Foxa1
uniprot id: A0A6I9M257
names: Subcellular Location Annotation
messages: Nucleus

230844:Tnfsf8
gene id: 230844:Tnfsf8
uniprot id: A0A6I9LMT4
names: Similarity
messages: Belongs to the tumor necrosis factor family.

230844:Myoz3
gene id: 230844:Myoz3
uniprot id: A0A6I9LUG3
names: Similarity
messages: Belongs to the myozenin family.

230844:LOC102925381
gene id: 230844:LOC102925381
uniprot id: A0A6I9LLB3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calycin superfamily. Lipocalin family.
messages: Secreted

230844:Tubgcp6
gene id: 230844:Tubgcp6
uniprot id: A0A6I9L3Z6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TUBGCP family.
messages: centrosome

230844:Rps18
gene id: 230844:Rps18
uniprot id: A0A6I9MM46
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Component of the small ribosomal subunit.

230844:Sfrp2
gene id: 230844:Sfrp2
uniprot id: A0A6I9M093
names: Caution
names: Similarity
messages: Belongs to the secreted frizzled-related protein (sFRP) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

230844:Fam229a
gene id: 230844:Fam229a
uniprot id: A0A6I9M8M3
names: Similarity
messages: Belongs to the FAM229 family.

230844:Nde1
gene id: 230844:Nde1
uniprot id: A0A6I9LST3
uniprot id: A0A6J0DY78
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nudE family.
messages: centrosome
messages: kinetochore
messages: spindle

230844:Tomm40l
gene id: 230844:Tomm40l
uniprot id: A0A6I9LUL6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Tom40 family.
messages: Membrane
messages: Mitochondrion outer membrane

230844:Ptpn22
gene id: 230844:Ptpn22
uniprot id: A0A6J0DIL4
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class 4 subfamily.

230844:LOC102926040
gene id: 230844:LOC102926040
uniprot id: A0A6I9M3L4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:LOC102907276
gene id: 230844:LOC102907276
uniprot id: A0A6I9L3P8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

230844:Gtpbp4
gene id: 230844:Gtpbp4
uniprot id: A0A6I9LC22
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. NOG subfamily.
messages: Involved in the biogenesis of the 60S ribosomal subunit.
messages: nucleolus

230844:LOC102926742
gene id: 230844:LOC102926742
uniprot id: A0A6I9M1F0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cathelicidin family.
messages: Secreted

230844:Npvf
gene id: 230844:Npvf
uniprot id: A0A6I9LNC7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FARP (FMRFamide related peptide) family.
messages: Secreted

230844:LOC102923678
gene id: 230844:LOC102923678
uniprot id: A0A6J0D3C5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the shugoshin family.
messages: centromere

230844:LOC102903179
gene id: 230844:LOC102903179
uniprot id: A0A6I9MM41
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:LOC102915517
gene id: 230844:LOC102915517
uniprot id: A0A6I9LZ13
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MOZART2 family.
messages: centrosome
messages: spindle

230844:LOC102904640
gene id: 230844:LOC102904640
uniprot id: A0A6I9ME23
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:LOC102923849
gene id: 230844:LOC102923849
uniprot id: A0A6I9LPV8
names: Similarity
names: Subunit
messages: Belongs to the histone H3 family.
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

230844:Scn9a
gene id: 230844:Scn9a
uniprot id: A0A6J0D8U3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium channel (TC 1.A.1.10) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient.
messages: Membrane

230844:Ppp1r9b
gene id: 230844:Ppp1r9b
uniprot id: A0A6I9KW07
names: Subcellular Location Annotation
messages: cytoskeleton

230844:Zdhhc2
gene id: 230844:Zdhhc2
uniprot id: A0A6I9KZJ1
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

230844:Grb10
gene id: 230844:Grb10
uniprot id: A0A6J0CVZ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GRB7/10/14 family.
messages: Cytoplasm

230844:P2ry1
gene id: 230844:P2ry1
uniprot id: A0A6I9L3P7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Znf687
gene id: 230844:Znf687
uniprot id: A0A6I9MGD2
names: Function
names: Subcellular Location Annotation
messages: May be involved in transcriptional regulation.
messages: Nucleus

230844:Nacc2
gene id: 230844:Nacc2
uniprot id: A0A6I9LR81
names: Subcellular Location Annotation
messages: Nucleus

230844:Smim15
gene id: 230844:Smim15
uniprot id: A0A6I9MGR3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SMIM15 family.
messages: Membrane

230844:Dram1
gene id: 230844:Dram1
uniprot id: A0A6I9LIL0
names: Subcellular Location Annotation
messages: Membrane

230844:Runx1t1
gene id: 230844:Runx1t1
uniprot id: A0A6I9LGH4
uniprot id: A0A6I9LW89
uniprot id: A0A6J0DN11
uniprot id: A0A6J0DQP5
names: Similarity
messages: Belongs to the CBFA2T family.

230844:LOC102909784
gene id: 230844:LOC102909784
uniprot id: A0A6I9MCH3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Rpl3
gene id: 230844:Rpl3
uniprot id: A0A6I9LA23
names: Similarity
messages: Belongs to the universal ribosomal protein uL3 family.

230844:Pdcl3
gene id: 230844:Pdcl3
uniprot id: A0A6I9LKU5
names: Similarity
messages: Belongs to the phosducin family.

230844:Map3k7
gene id: 230844:Map3k7
uniprot id: A0A6I9L1P0
uniprot id: A0A6I9L9L6
names: Activity Regulation
names: Similarity
names: Subcellular Location Annotation
messages: Activated by pro-inflammatory cytokines and in response to physical and chemical stresses, including osmotic stress, oxidative stress, arsenic and ultraviolet light irradiation. Activated by 'Lys-63'-linked polyubiquitination and by autophosphorylation.
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.
messages: Cytoplasm

230844:Ccdc43
gene id: 230844:Ccdc43
uniprot id: A0A6I9KZG7
uniprot id: A0A6J0D6S3
names: Similarity
messages: Belongs to the CCDC43 family.

230844:Vps4b
gene id: 230844:Vps4b
uniprot id: A0A6I9M768
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAA ATPase family.
messages: Endosome membrane
messages: Late endosome membrane
messages: Membrane

230844:Scrib
gene id: 230844:Scrib
uniprot id: A0A6I9LS75
uniprot id: A0A6I9M2S8
uniprot id: A0A6I9M4C1
uniprot id: A0A6I9M8D1
uniprot id: A0A6J0EBX7
names: Similarity
messages: Belongs to the LAP (LRR and PDZ) protein family.

230844:Msmb
gene id: 230844:Msmb
uniprot id: A0A6I9MC82
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the beta-microseminoprotein family.
messages: Secreted

230844:LOC102904835
gene id: 230844:LOC102904835
uniprot id: A0A6I9MJD2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Kcnn1
gene id: 230844:Kcnn1
uniprot id: A0A6J0E7B8
names: Subcellular Location Annotation
messages: Membrane

230844:LOC102906644
gene id: 230844:LOC102906644
uniprot id: A0A6I9M544
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:LOC102921467
gene id: 230844:LOC102921467
uniprot id: A0A6I9LZ72
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Dgkh
gene id: 230844:Dgkh
uniprot id: A0A6J0E515
uniprot id: A0A6J0E6W8
uniprot id: A0A6J0E8K7
names: Similarity
messages: Belongs to the eukaryotic diacylglycerol kinase family.

230844:Prkdc
gene id: 230844:Prkdc
uniprot id: A0A6I9MLL0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PI3/PI4-kinase family.
messages: nucleolus

230844:Ogdhl
gene id: 230844:Ogdhl
uniprot id: A0A6J0D7N9
names: Similarity
messages: Belongs to the alpha-ketoglutarate dehydrogenase family.

230844:LOC102919275
gene id: 230844:LOC102919275
uniprot id: A0A6I9MJR3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Uggt2
gene id: 230844:Uggt2
uniprot id: A0A6J0DBF5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 8 family.
messages: Endoplasmic reticulum lumen

230844:Vps35
gene id: 230844:Vps35
uniprot id: A0A6I9L5B2
names: Function
names: Similarity
messages: Belongs to the VPS35 family.
messages: Plays a role in vesicular protein sorting.

230844:Wdr91
gene id: 230844:Wdr91
uniprot id: A0A6I9M4Y3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat WDR91 family.
messages: Early endosome membrane
messages: Endosome membrane
messages: Late endosome membrane
messages: Membrane

230844:Limd1
gene id: 230844:Limd1
uniprot id: A0A6I9M051
names: Similarity
messages: Belongs to the zyxin/ajuba family.

230844:Entpd2
gene id: 230844:Entpd2
uniprot id: A0A6I9LL70
names: Similarity
messages: Belongs to the GDA1/CD39 NTPase family.

230844:Ak3
gene id: 230844:Ak3
uniprot id: A0A6I9LVE5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family. AK3 subfamily.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon GTP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent GTP hydrolysis.
messages: Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Has GTP:AMP phosphotransferase and ITP:AMP phosphotransferase activities.
messages: Mitochondrion matrix
messages: Monomer.

230844:Dio1
gene id: 230844:Dio1
uniprot id: A0A6I9LEJ4
names: Function
names: Similarity
messages: Belongs to the iodothyronine deiodinase family.
messages: Responsible for the deiodination of T4 (3,5,3',5'-tetraiodothyronine).

230844:Cfap36
gene id: 230844:Cfap36
uniprot id: A0A6I9MPJ7
uniprot id: A0A6J0CY71
names: Similarity
messages: Belongs to the CFAP36 family.

230844:Rbbp4
gene id: 230844:Rbbp4
uniprot id: A0A6I9MIA9
names: Subcellular Location Annotation
messages: Nucleus

230844:Dydc2
gene id: 230844:Dydc2
uniprot id: A0A6J0CTJ7
names: Similarity
messages: Belongs to the dpy-30 family.

230844:Glyctk
gene id: 230844:Glyctk
uniprot id: A0A6I9MHZ9
uniprot id: A0A6J0CLZ2
names: Similarity
messages: Belongs to the glycerate kinase type-2 family.

230844:Psma7
gene id: 230844:Psma7
uniprot id: A0A6I9L3S7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1A family.
messages: Cytoplasm
messages: Nucleus
messages: The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits.

230844:Afg1l
gene id: 230844:Afg1l
uniprot id: A0A6I9LPI0
names: Similarity
messages: Belongs to the AFG1 ATPase family.

230844:Pif1
gene id: 230844:Pif1
uniprot id: A0A6I9LM47
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the helicase family. PIF1 subfamily.
messages: DNA-dependent ATPase and 5'-3' DNA helicase required for the maintenance of both mitochondrial and nuclear genome stability. Efficiently unwinds G-quadruplex (G4) DNA structures and forked RNA-DNA hybrids. Resolves G4 structures, preventing replication pausing and double-strand breaks (DSBs) at G4 motifs. Involved in the maintenance of telomeric DNA. Inhibits telomere elongation, de novo telomere formation and telomere addition to DSBs via catalytic inhibition of telomerase. Reduces the processivity of telomerase by displacing active telomerase from DNA ends. Releases telomerase by unwinding the short telomerase RNA/telomeric DNA hybrid that is the intermediate in the telomerase reaction. Possesses an intrinsic strand annealing activity.
messages: Mitochondrion
messages: Monomer. Interacts with telomerase.
messages: Nucleus

230844:Cdnf
gene id: 230844:Cdnf
uniprot id: A0A6I9LWI2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ARMET family.
messages: Secreted

230844:Nagk
gene id: 230844:Nagk
uniprot id: A0A6I9MCC9
names: Similarity
messages: Belongs to the eukaryotic-type N-acetylglucosamine kinase family.

230844:Cd164
gene id: 230844:Cd164
uniprot id: A0A6I9LFG5
uniprot id: A0A6I9LQN8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CD164 family.
messages: Membrane

230844:Chrnd
gene id: 230844:Chrnd
uniprot id: A0A6I9LXY5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

230844:Nubp2
gene id: 230844:Nubp2
uniprot id: A0A6J0E2G3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family. NUBP2/CFD1 subfamily.
messages: Binds 4 [4Fe-4S] clusters per heterotetramer. Contains two stable clusters in the N-termini of NUBP1 and two labile, bridging clusters between subunits of the NUBP1-NUBP2 heterotetramer.
messages: Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery. Required for maturation of extramitochondrial Fe-S proteins. The NUBP1-NUBP2 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins.
messages: Cytoplasm
messages: Heterotetramer of 2 NUBP1 and 2 NUBP2 chains. Interacts with KIFC1.
messages: Nucleus
messages: centrosome

230844:Trappc4
gene id: 230844:Trappc4
uniprot id: A0A6I9LYI0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAPP small subunits family.
messages: Endoplasmic reticulum
messages: Part of the multisubunit transport protein particle (TRAPP) complex.
messages: cis-Golgi network

230844:Syngr3
gene id: 230844:Syngr3
uniprot id: A0A6I9L844
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptogyrin family.
messages: Membrane

230844:Nav2
gene id: 230844:Nav2
uniprot id: A0A6J0E691
uniprot id: A0A6J0E695
uniprot id: A0A6J0E847
uniprot id: A0A6J0E852
uniprot id: A0A6J0E9Z0
uniprot id: A0A6J0EC73
uniprot id: A0A6J0EDM0
uniprot id: A0A6J0EDM8
names: Similarity
messages: Belongs to the Nav/unc-53 family.

230844:Mapk3
gene id: 230844:Mapk3
uniprot id: A0A6I9LDB4
names: Subcellular Location Annotation
messages: Cytoplasm
messages: caveola
messages: focal adhesion

230844:Banf2
gene id: 230844:Banf2
uniprot id: A0A6J0DP76
names: Subcellular Location Annotation
messages: Nucleus

230844:Rad23a
gene id: 230844:Rad23a
uniprot id: A0A6I9M520
uniprot id: A0A6I9MLH7
uniprot id: A0A6J0CU00
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RAD23 family.
messages: Cytoplasm
messages: Multiubiquitin chain receptor involved in modulation of proteasomal degradation. Involved in nucleotide excision repair.
messages: Nucleus

230844:LOC102921316
gene id: 230844:LOC102921316
uniprot id: A0A6I9LE68
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Fntb
gene id: 230844:Fntb
uniprot id: A0A6I9L8F1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the protein prenyltransferase subunit beta family.
messages: Binds 1 zinc ion per subunit.
messages: Essential subunit of the farnesyltransferase complex. Catalyzes the transfer of a farnesyl moiety from farnesyl diphosphate to a cysteine at the fourth position from the C-terminus of several proteins having the C-terminal sequence Cys-aliphatic-aliphatic-X.
messages: Heterodimer of FNTA and FNTB.

230844:Alg5
gene id: 230844:Alg5
uniprot id: A0A6I9LE92
names: Similarity
messages: Belongs to the glycosyltransferase 2 family.

230844:LOC102913824
gene id: 230844:LOC102913824
uniprot id: A0A6I9LD54
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:LOC102915851
gene id: 230844:LOC102915851
uniprot id: A0A6I9M4T5
uniprot id: A0A6I9M4U0
uniprot id: A0A6I9MBX1
uniprot id: A0A6I9MFY1
uniprot id: A0A6I9MJA4
uniprot id: A0A6I9ML98
uniprot id: A0A6J0CPH0
uniprot id: A0A6J0CPH2
uniprot id: A0A6J0CTN8
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: Potential calcium-dependent cell-adhesion protein. May be involved in the establishment and maintenance of specific neuronal connections in the brain.

230844:Hspb1
gene id: 230844:Hspb1
uniprot id: A0A6I9L163
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small heat shock protein (HSP20) family.
messages: Nucleus
messages: spindle

230844:Sec61a1
gene id: 230844:Sec61a1
uniprot id: A0A6I9MG47
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecY/SEC61-alpha family.
messages: Endoplasmic reticulum membrane
messages: Membrane

230844:Pir
gene id: 230844:Pir
uniprot id: A0A6J0CX71
names: Similarity
messages: Belongs to the pirin family.

230844:Satb1
gene id: 230844:Satb1
uniprot id: A0A6I9M314
uniprot id: A0A6J0E7F6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CUT homeobox family.
messages: Nucleus

230844:LOC102928452
gene id: 230844:LOC102928452
uniprot id: A0A6I9M532
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Cfap298
gene id: 230844:Cfap298
uniprot id: A0A6I9LR71
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CFAP298 family.
messages: cilium basal body

230844:Susd2
gene id: 230844:Susd2
uniprot id: A0A6I9L8F9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

230844:Akap8l
gene id: 230844:Akap8l
uniprot id: A0A6I9LVQ7
uniprot id: A0A6I9MC01
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AKAP95 family.
messages: Nucleus matrix

230844:Ctse
gene id: 230844:Ctse
uniprot id: A0A6I9M7E8
names: Similarity
messages: Belongs to the peptidase A1 family.

230844:Sumf1
gene id: 230844:Sumf1
uniprot id: A0A6I9MJL5
uniprot id: A0A6J0CR79
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfatase-modifying factor family.
messages: Endoplasmic reticulum lumen

230844:Tmem63a
gene id: 230844:Tmem63a
uniprot id: A0A6J0CZ20
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CSC1 (TC 1.A.17) family.
messages: Membrane

230844:Slc26a11
gene id: 230844:Slc26a11
uniprot id: A0A6I9M4R4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Membrane

230844:LOC102908695
gene id: 230844:LOC102908695
uniprot id: A0A6J0DGH3
names: Cofactor
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS27 family.
messages: Binds 1 zinc ion per subunit.

230844:Anxa4
gene id: 230844:Anxa4
uniprot id: A0A6I9LU28
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: A pair of annexin repeats may form one binding site for calcium and phospholipid.
messages: Belongs to the annexin family.
messages: Zymogen granule membrane

230844:Mmp2
gene id: 230844:Mmp2
uniprot id: A0A6I9LS46
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M10A family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Can bind about 5 Ca(2+) ions per subunit.
messages: extracellular matrix

230844:Kcng4
gene id: 230844:Kcng4
uniprot id: A0A6I9M5X5
names: Subcellular Location Annotation
messages: Membrane

230844:LOC102909999
gene id: 230844:LOC102909999
uniprot id: A0A6I9LF95
names: Similarity
messages: Belongs to the LCE family.

230844:LOC107402354
gene id: 230844:LOC107402354
uniprot id: A0A6J0DW35
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS27 family.

230844:Ropn1
gene id: 230844:Ropn1
uniprot id: A0A6I9L0I8
uniprot id: A0A6I9L833
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ropporin family.
messages: flagellum

230844:LOC102911132
gene id: 230844:LOC102911132
uniprot id: A0A6J0ECD7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IFI6/IFI27 family.
messages: Membrane

230844:Ergic3
gene id: 230844:Ergic3
uniprot id: A0A6I9LQG1
uniprot id: A0A6I9M0W9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ERGIC family.
messages: Endoplasmic reticulum membrane
messages: Endoplasmic reticulum-Golgi intermediate compartment membrane
messages: Golgi apparatus membrane
messages: Plays a role in transport between endoplasmic reticulum and Golgi.

230844:LOC102911575
gene id: 230844:LOC102911575
uniprot id: A0A6I9MLX0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Icos
gene id: 230844:Icos
uniprot id: A0A6J0D7H2
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Enhances all basic T-cell responses to a foreign antigen, namely proliferation, secretion of lymphokines, up-regulation of molecules that mediate cell-cell interaction, and effective help for antibody secretion by B-cells. Essential both for efficient interaction between T and B-cells and for normal antibody responses to T-cell dependent antigens. Does not up-regulate the production of interleukin-2, but superinduces the synthesis of interleukin-10. Prevents the apoptosis of pre-activated T-cells. Plays a critical role in CD40-mediated class switching of immunoglobin isotypes.
messages: Homodimer; disulfide-linked.
messages: Membrane

230844:Acsm3
gene id: 230844:Acsm3
uniprot id: A0A6J0DUP5
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

230844:LOC102910972
gene id: 230844:LOC102910972
uniprot id: A0A6I9M7P5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:B4galt3
gene id: 230844:B4galt3
uniprot id: A0A6J0E7N7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 7 family.
messages: Golgi apparatus membrane
messages: Membrane
messages: Responsible for the synthesis of complex-type N-linked oligosaccharides in many glycoproteins as well as the carbohydrate moieties of glycolipids.

230844:Phb2
gene id: 230844:Phb2
uniprot id: A0A6I9M871
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prohibitin family.
messages: Cell membrane
messages: Membrane
messages: Mitochondrion inner membrane

230844:Alox5
gene id: 230844:Alox5
uniprot id: A0A6I9LGR6
names: Caution
names: Cofactor
names: Similarity
messages: Belongs to the lipoxygenase family.
messages: Binds 1 Fe cation per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

230844:Slc46a1
gene id: 230844:Slc46a1
uniprot id: A0A6I9LE33
names: Subcellular Location Annotation
messages: Membrane

230844:Ptger1
gene id: 230844:Ptger1
uniprot id: A0A6I9MFA4
names: Subcellular Location Annotation
messages: Membrane

230844:Rack1
gene id: 230844:Rack1
uniprot id: A0A6I9M407
names: Similarity
messages: Belongs to the WD repeat G protein beta family. Ribosomal protein RACK1 subfamily.

230844:LOC102907414
gene id: 230844:LOC102907414
uniprot id: A0A6I9MKV6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Gjb1
gene id: 230844:Gjb1
uniprot id: A0A6I9LMC5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins. Interacts with CNST.
messages: Belongs to the connexin family. Beta-type (group I) subfamily.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

230844:Supt20h
gene id: 230844:Supt20h
uniprot id: A0A6I9L5N1
uniprot id: A0A6J0D896
uniprot id: A0A6J0D9R7
uniprot id: A0A6J0DA18
uniprot id: A0A6J0DEV8
names: Similarity
messages: Belongs to the SPT20 family.

230844:Tbr1
gene id: 230844:Tbr1
uniprot id: A0A6I9LL18
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

230844:Lsm1
gene id: 230844:Lsm1
uniprot id: A0A6I9LHH6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the snRNP Sm proteins family.
messages: Cytoplasm
messages: Interacts with SLBP; interaction with SLBP occurs when histone mRNA is being rapidly degraded during the S phase. LSm subunits form a heteromer with a donut shape.
messages: P-body
messages: Plays a role in the degradation of histone mRNAs, the only eukaryotic mRNAs that are not polyadenylated. Probably also part of an LSm subunits-containing complex involved in the general process of mRNA degradation.

230844:Ndufa7
gene id: 230844:Ndufa7
uniprot id: A0A6I9MB71
names: Function
names: Similarity
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFA7 subunit family.
messages: Complex I is composed of 45 different subunits.

230844:Kif19
gene id: 230844:Kif19
uniprot id: A0A6I9KSR4
uniprot id: A0A6J0D0V4
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

230844:Tm4sf5
gene id: 230844:Tm4sf5
uniprot id: A0A6I9MHD7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L6 tetraspanin family.
messages: Membrane

230844:E2f5
gene id: 230844:E2f5
uniprot id: A0A6J0CMX4
names: Similarity
messages: Belongs to the E2F/DP family.

230844:Slc9a3r1
gene id: 230844:Slc9a3r1
uniprot id: A0A6I9MIY3
names: Function
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Cell membrane
messages: Endomembrane system
messages: Scaffold protein that connects plasma membrane proteins with members of the ezrin/moesin/radixin family and thereby helps to link them to the actin cytoskeleton and to regulate their surface expression.

230844:Ddx18
gene id: 230844:Ddx18
uniprot id: A0A6I9LL10
names: Domain
names: Function
names: Similarity
messages: Belongs to the DEAD box helicase family. DDX18/HAS1 subfamily.
messages: RNA helicase.
messages: The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.

230844:Galnt13
gene id: 230844:Galnt13
uniprot id: A0A6I9L7E7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
messages: Golgi apparatus membrane
messages: Membrane

230844:LOC102921989
gene id: 230844:LOC102921989
uniprot id: A0A6J0E984
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS26 family.

230844:Rnft2
gene id: 230844:Rnft2
uniprot id: A0A6I9L064
names: Subcellular Location Annotation
messages: Membrane

230844:Pspc1
gene id: 230844:Pspc1
uniprot id: A0A6I9M6M9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PSPC family.
messages: Cytoplasm
messages: Nucleus matrix
messages: Nucleus speckle
messages: nucleolus

230844:Gpr89a
gene id: 230844:Gpr89a
uniprot id: A0A6I9LF58
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Golgi pH regulator (TC 1.A.38) family.
messages: Membrane

230844:Sec16a
gene id: 230844:Sec16a
uniprot id: A0A6I9LC01
uniprot id: A0A6I9LLY3
uniprot id: A0A6J0DGL0
uniprot id: A0A6J0DIY2
uniprot id: A0A6J0DIY8
uniprot id: A0A6J0DJ05
uniprot id: A0A6J0DJ92
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SEC16 family.
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Plays a role in the organization of the endoplasmic reticulum exit sites (ERES), also known as transitional endoplasmic reticulum (tER). Required for secretory cargo traffic from the endoplasmic reticulum to the Golgi apparatus.
messages: SEC16A and SEC16B are each present in multiple copies in a heteromeric complex.

230844:Dnph1
gene id: 230844:Dnph1
uniprot id: A0A6I9LUZ3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 2'-deoxynucleoside 5'-phosphate N-hydrolase 1 family.
messages: Catalyzes the cleavage of the N-glycosidic bond of deoxyribonucleoside 5'-monophosphates to yield deoxyribose 5-phosphate and a purine or pyrimidine base. Deoxyribonucleoside 5'-monophosphates containing purine bases are preferred to those containing pyrimidine bases.
messages: Cytoplasm
messages: Monomer and homodimer.
messages: Nucleus

230844:Pvalb
gene id: 230844:Pvalb
uniprot id: A0A6I9MD22
names: Function
names: Similarity
messages: Belongs to the parvalbumin family.
messages: In muscle, parvalbumin is thought to be involved in relaxation after contraction. It binds two calcium ions.

230844:Med13
gene id: 230844:Med13
uniprot id: A0A6I9LW26
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 13 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex, which is composed of MED1, MED4, MED6, MED7, MED8, MED9, MED10, MED11, MED12, MED13, MED13L, MED14, MED15, MED16, MED17, MED18, MED19, MED20, MED21, MED22, MED23, MED24, MED25, MED26, MED27, MED29, MED30, MED31, CCNC, CDK8 and CDC2L6/CDK11. The MED12, MED13, CCNC and CDK8 subunits form a distinct module termed the CDK8 module. Mediator containing the CDK8 module is less active than Mediator lacking this module in supporting transcriptional activation. Individual preparations of the Mediator complex lacking one or more distinct subunits have been variously termed ARC, CRSP, DRIP, PC2, SMCC and TRAP.
messages: Nucleus

230844:LOC102912501
gene id: 230844:LOC102912501
uniprot id: A0A6I9LV80
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:LOC102903704
gene id: 230844:LOC102903704
uniprot id: A0A6I9MEJ2
names: Similarity
messages: Belongs to the PRAME family.

230844:LOC102914479
gene id: 230844:LOC102914479
uniprot id: A0A6I9M698
names: Similarity
messages: Belongs to the aldo/keto reductase family.

230844:Atg4a
gene id: 230844:Atg4a
uniprot id: A0A6I9KZ16
uniprot id: A0A6J0CWV2
uniprot id: A0A6J0CXK4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C54 family.
messages: Cysteine protease that plays a key role in autophagy by mediating both proteolytic activation and delipidation of ATG8 family proteins.
messages: Cytoplasm

230844:LOC102924681
gene id: 230844:LOC102924681
uniprot id: A0A6J0EDD5
names: Subcellular Location Annotation
messages: Secreted

230844:Marveld3
gene id: 230844:Marveld3
uniprot id: A0A6I9KZT5
uniprot id: A0A6I9L775
names: Subcellular Location Annotation
messages: Membrane

230844:LOC102914934
gene id: 230844:LOC102914934
uniprot id: A0A6I9LGF5
uniprot id: A0A6J0D6G2
names: Similarity
messages: Belongs to the DPH3 family.

230844:LOC102926494
gene id: 230844:LOC102926494
uniprot id: A0A6I9LDT1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Gale
gene id: 230844:Gale
uniprot id: A0A6I9LQU8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Catalyzes two distinct but analogous reactions: the reversible epimerization of UDP-glucose to UDP-galactose and the reversible epimerization of UDP-N-acetylglucosamine to UDP-N-acetylgalactosamine. The reaction with UDP-Gal plays a critical role in the Leloir pathway of galactose catabolism in which galactose is converted to the glycolytic intermediate glucose 6-phosphate. It contributes to the catabolism of dietary galactose and enables the endogenous biosynthesis of both UDP-Gal and UDP-GalNAc when exogenous sources are limited. Both UDP-sugar interconversions are important in the synthesis of glycoproteins and glycolipids.
messages: Homodimer.

230844:Prokr2
gene id: 230844:Prokr2
uniprot id: A0A6I9LHR9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

230844:Cds2
gene id: 230844:Cds2
uniprot id: A0A6I9LXJ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Catalyzes the conversion of phosphatidic acid (PA) to CDP-diacylglycerol (CDP-DAG), an essential intermediate in the synthesis of phosphatidylglycerol, cardiolipin and phosphatidylinositol.
messages: Membrane

230844:Vps37d
gene id: 230844:Vps37d
uniprot id: A0A6I9KUZ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VPS37 family.
messages: Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies. May be involved in cell growth and differentiation.
messages: Endosome membrane
messages: Late endosome membrane

230844:Pds5a
gene id: 230844:Pds5a
uniprot id: A0A6I9LBT9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PDS5 family.
messages: Nucleus

230844:Popdc3
gene id: 230844:Popdc3
uniprot id: A0A6I9LSJ6
names: Similarity
messages: Belongs to the popeye family.

230844:Eno2
gene id: 230844:Eno2
uniprot id: A0A6I9M356
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Cytoplasm

230844:LOC102910900
gene id: 230844:LOC102910900
uniprot id: A0A6J0E0N2
names: Similarity
messages: Belongs to the aldo/keto reductase family.

230844:LOC102927739
gene id: 230844:LOC102927739
uniprot id: A0A6I9LJI8
names: Similarity
messages: Belongs to the zyxin/ajuba family.

230844:Hsd3b7
gene id: 230844:Hsd3b7
uniprot id: A0A6I9L4P8
uniprot id: A0A6I9LH36
names: Similarity
messages: Belongs to the 3-beta-HSD family.

230844:Hhatl
gene id: 230844:Hhatl
uniprot id: A0A6I9LHE7
uniprot id: A0A6I9LQW2
names: Subcellular Location Annotation
messages: Membrane

230844:LOC102926880
gene id: 230844:LOC102926880
uniprot id: A0A6I9M699
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Cd164l2
gene id: 230844:Cd164l2
uniprot id: A0A6I9L278
uniprot id: A0A6I9LA80
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CD164 family.
messages: Membrane

230844:C4H9orf116
gene id: 230844:C4H9orf116
uniprot id: A0A6I9MFC5
names: Subcellular Location Annotation
names: Subunit
messages: Interacts with CFAP53, ODAD1 and ODAD3; the interactions link the outer dynein arms docking complex (ODA-DC) to the internal microtubule inner proteins (MIP) in cilium axoneme.
messages: cilium axoneme

230844:As3mt
gene id: 230844:As3mt
uniprot id: A0A6I9LRT4
names: Similarity
messages: Belongs to the methyltransferase superfamily. Arsenite methyltransferase family.

230844:Il7
gene id: 230844:Il7
uniprot id: A0A6J0D8X5
uniprot id: A0A6J0DFN2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IL-7/IL-9 family.
messages: Hematopoietic cytokine that plays an essential role in the development, expansion, and survival of naive and memory T-cells and B-cells thereby regulating the number of mature lymphocytes and maintaining lymphoid homeostasis.
messages: Interacts with IL7R and CSF2RG.
messages: Secreted

230844:Galnt15
gene id: 230844:Galnt15
uniprot id: A0A6I9M537
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
messages: Golgi apparatus membrane
messages: Membrane

230844:Nusap1
gene id: 230844:Nusap1
uniprot id: A0A6I9LVP7
uniprot id: A0A6I9MBY7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NUSAP family.
messages: Cytoplasm

230844:Gja1
gene id: 230844:Gja1
uniprot id: A0A6I9LRX1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family. Alpha-type (group II) subfamily.
messages: Cell membrane
messages: Endoplasmic reticulum
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

230844:LOC102926967
gene id: 230844:LOC102926967
uniprot id: A0A6I9LNJ2
names: Similarity
messages: Belongs to the small GTPase superfamily. Arf family.

230844:LOC102916027
gene id: 230844:LOC102916027
uniprot id: A0A6I9M609
names: Similarity
messages: Belongs to the serpin family.

230844:Etfdh
gene id: 230844:Etfdh
uniprot id: A0A6I9LMA3
names: Cofactor
names: Function
messages: Accepts electrons from ETF and reduces ubiquinone.
messages: Binds 1 [4Fe-4S] cluster.

230844:Bdh1
gene id: 230844:Bdh1
uniprot id: A0A6J0D1K5
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

230844:Aurkaip1
gene id: 230844:Aurkaip1
uniprot id: A0A6I9M8S4
names: Similarity
messages: Belongs to the mitochondrion-specific ribosomal protein mS38 family.

230844:Ndrg2
gene id: 230844:Ndrg2
uniprot id: A0A6I9MAV7
uniprot id: A0A6J0CIQ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NDRG family.
messages: Contributes to the regulation of the Wnt signaling pathway. Down-regulates CTNNB1-mediated transcriptional activation of target genes. May be involved in neuron differentiation.
messages: Cytoplasm

230844:Riok2
gene id: 230844:Riok2
uniprot id: A0A6I9L2S4
names: Similarity
messages: Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family.

230844:Pycr2
gene id: 230844:Pycr2
uniprot id: A0A6I9L7B9
names: Similarity
messages: Belongs to the pyrroline-5-carboxylate reductase family.

230844:Pml
gene id: 230844:Pml
uniprot id: A0A6J0DWV3
uniprot id: A0A6J0DWW0
names: Subcellular Location Annotation
messages: Cytoplasm

230844:Dglucy
gene id: 230844:Dglucy
uniprot id: A0A6I9M7R7
names: Similarity
messages: Belongs to the D-glutamate cyclase family.

230844:Naa40
gene id: 230844:Naa40
uniprot id: A0A6I9LDB5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetyltransferase family. NAA40 subfamily.
messages: Cytoplasm
messages: Nucleus

230844:St6galnac3
gene id: 230844:St6galnac3
uniprot id: A0A6J0E6Q3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

230844:LOC102920923
gene id: 230844:LOC102920923
uniprot id: A0A6I9MLG0
names: Subcellular Location Annotation
messages: Membrane

230844:LOC102913873
gene id: 230844:LOC102913873
uniprot id: A0A6I9L3U7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Cadm4
gene id: 230844:Cadm4
uniprot id: A0A6J0CKM1
names: Similarity
messages: Belongs to the nectin family.

230844:Dbh
gene id: 230844:Dbh
uniprot id: A0A6I9M5T9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the copper type II ascorbate-dependent monooxygenase family.
messages: Conversion of dopamine to noradrenaline.
messages: Homotetramer; composed of two disulfide-linked dimers.
messages: chromaffin granule lumen
messages: chromaffin granule membrane
messages: secretory vesicle lumen
messages: secretory vesicle membrane

230844:Slc8a2
gene id: 230844:Slc8a2
uniprot id: A0A6I9MC94
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. SLC8 subfamily.
messages: Cell membrane
messages: Membrane

230844:Galk1
gene id: 230844:Galk1
uniprot id: A0A6I9MBB1
names: Similarity
messages: Belongs to the GHMP kinase family. GalK subfamily.

230844:Cubn
gene id: 230844:Cubn
uniprot id: A0A6I9LNX1
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

230844:Scarf2
gene id: 230844:Scarf2
uniprot id: A0A6J0DNR9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

230844:LOC102918053
gene id: 230844:LOC102918053
uniprot id: A0A6J0CUF4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Dis3
gene id: 230844:Dis3
uniprot id: A0A6I9LF44
uniprot id: A0A6I9LJ95
names: Similarity
messages: Belongs to the RNR ribonuclease family.

230844:Rngtt
gene id: 230844:Rngtt
uniprot id: A0A6I9L9M6
uniprot id: A0A6J0D2H6
uniprot id: A0A6J0D449
uniprot id: A0A6J0D8D8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bifunctional mRNA-capping enzyme exhibiting RNA 5'-triphosphate monophosphatase activity in the N-terminal part and mRNA guanylyltransferase activity in the C-terminal part. Catalyzes the first two steps of cap formation: by removing the gamma-phosphate from the 5'-triphosphate end of nascent mRNA to yield a diphosphate end, and by transferring the GMP moiety of GTP to the 5'-diphosphate terminus of RNA via a covalent enzyme-GMP reaction intermediate.
messages: In the C-terminal section; belongs to the eukaryotic GTase family.
messages: In the N-terminal section; belongs to the non-receptor class of the protein-tyrosine phosphatase family.
messages: Nucleus

230844:Plbd2
gene id: 230844:Plbd2
uniprot id: A0A6I9KZY7
names: Function
names: Similarity
messages: Belongs to the phospholipase B-like family.
messages: Putative phospholipase.

230844:Vegfc
gene id: 230844:Vegfc
uniprot id: A0A6I9KUA2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PDGF/VEGF growth factor family.
messages: Secreted

230844:Kmo
gene id: 230844:Kmo
uniprot id: A0A6I9MC24
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aromatic-ring hydroxylase family. KMO subfamily.
messages: Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid, a neurotoxic NMDA receptor antagonist and potential endogenous inhibitor of NMDA receptor signaling in axonal targeting, synaptogenesis and apoptosis during brain development. Quinolinic acid may also affect NMDA receptor signaling in pancreatic beta cells, osteoblasts, myocardial cells, and the gastrointestinal tract.
messages: Mitochondrion outer membrane

230844:LOC102919593
gene id: 230844:LOC102919593
uniprot id: A0A6I9LDS5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calycin superfamily. Lipocalin family.
messages: Secreted

230844:Fev
gene id: 230844:Fev
uniprot id: A0A6I9KWE8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

230844:Arrdc3
gene id: 230844:Arrdc3
uniprot id: A0A6I9LT41
uniprot id: A0A6I9M9H4
names: Similarity
messages: Belongs to the arrestin family.

230844:Oplah
gene id: 230844:Oplah
uniprot id: A0A6I9LWM9
uniprot id: A0A6J0E7V8
names: Similarity
messages: Belongs to the oxoprolinase family.

230844:Ttyh3
gene id: 230844:Ttyh3
uniprot id: A0A6I9M020
uniprot id: A0A6J0EFK4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tweety family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Probable chloride channel.

230844:Adamts19
gene id: 230844:Adamts19
uniprot id: A0A6I9LVS5
names: Caution
names: Cofactor
names: Subcellular Location Annotation
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

230844:LOC102919507
gene id: 230844:LOC102919507
uniprot id: A0A6I9LUT1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Dctn5
gene id: 230844:Dctn5
uniprot id: A0A6I9LAR5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dynactin subunits 5/6 family. Dynactin subunit 5 subfamily.
messages: cytoskeleton

230844:Aifm1
gene id: 230844:Aifm1
uniprot id: A0A6I9MCZ2
uniprot id: A0A6J0CQT2
names: Similarity
messages: Belongs to the FAD-dependent oxidoreductase family.

230844:LOC102928380
gene id: 230844:LOC102928380
uniprot id: A0A6I9MH09
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Atxn1l
gene id: 230844:Atxn1l
uniprot id: A0A6I9L780
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATXN1 family.
messages: Nucleus

230844:LOC102928089
gene id: 230844:LOC102928089
uniprot id: A0A6I9MJ52
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Dctn2
gene id: 230844:Dctn2
uniprot id: A0A6I9KY58
uniprot id: A0A6I9L5F6
uniprot id: A0A6J0CWY0
names: Similarity
messages: Belongs to the dynactin subunit 2 family.

230844:Ms4a10
gene id: 230844:Ms4a10
uniprot id: A0A6I9MGX3
names: Similarity
messages: Belongs to the MS4A family.

230844:Slc16a2
gene id: 230844:Slc16a2
uniprot id: A0A6I9MCG8
names: Subcellular Location Annotation
messages: Membrane

230844:Orai2
gene id: 230844:Orai2
uniprot id: A0A6J0DQ90
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Orai family.
messages: Membrane

230844:Decr2
gene id: 230844:Decr2
uniprot id: A0A6J0DBR4
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. 2,4-dienoyl-CoA reductase subfamily.
messages: Monomer, dimer and oligomer.

230844:Idh3a
gene id: 230844:Idh3a
uniprot id: A0A6I9L1I9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.
messages: Heterooligomer of subunits alpha (IDH3A), beta (IDH3B), and gamma (IDH3G) in the apparent ratio of 2:1:1. The heterodimer containing one IDH3A and one IDH3B subunit and the heterodimer containing one IDH3A and one IDH3G subunit assemble into a heterotetramer (which contains two subunits of IDH3A, one of IDH3B and one of IDH3G) and further into the heterooctamer.
messages: Mitochondrion

230844:Noc2l
gene id: 230844:Noc2l
uniprot id: A0A6I9LXQ3
names: Similarity
messages: Belongs to the NOC2 family.

230844:Rad52
gene id: 230844:Rad52
uniprot id: A0A6I9LWG1
uniprot id: A0A6J0E3M8
names: Similarity
messages: Belongs to the RAD52 family.

230844:Pitx2
gene id: 230844:Pitx2
uniprot id: A0A6I9KTF2
uniprot id: A0A6I9L213
uniprot id: A0A6J0D069
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the paired homeobox family. Bicoid subfamily.
messages: Nucleus

230844:Leo1
gene id: 230844:Leo1
uniprot id: A0A6I9L6F0
names: Similarity
messages: Belongs to the LEO1 family.

230844:Ocrl
gene id: 230844:Ocrl
uniprot id: A0A6J0CLR0
uniprot id: A0A6J0CND4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inositol 1,4,5-trisphosphate 5-phosphatase type II family.
messages: Early endosome membrane
messages: Endosome membrane
messages: Membrane
messages: phagosome membrane

230844:Hdhd2
gene id: 230844:Hdhd2
uniprot id: A0A6I9L6L6
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.

230844:Emc8
gene id: 230844:Emc8
uniprot id: A0A6I9M4G1
names: Similarity
messages: Belongs to the EMC8/EMC9 family.

230844:LOC102906797
gene id: 230844:LOC102906797
uniprot id: A0A6I9M6K1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Snx3
gene id: 230844:Snx3
uniprot id: A0A6I9LVA8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sorting nexin family.
messages: Early endosome
messages: Endosome
messages: phagosome

230844:LOC102924741
gene id: 230844:LOC102924741
uniprot id: A0A6I9MEM3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily.
messages: Membrane

230844:LOC102903399
gene id: 230844:LOC102903399
uniprot id: A0A6I9L5K1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BCP1 family.
messages: May promote cell cycle arrest by enhancing the inhibition of CDK2 activity by CDKN1A. May be required for repair of DNA damage by homologous recombination in conjunction with BRCA2. May not be involved in non-homologous end joining (NHEJ).
messages: Nucleus
messages: spindle pole

230844:Azgp1
gene id: 230844:Azgp1
uniprot id: A0A6I9MMB0
names: Similarity
messages: Belongs to the MHC class I family.

230844:LOC102914490
gene id: 230844:LOC102914490
uniprot id: A0A6I9M8V8
uniprot id: A0A6J0EIC6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alpha-casein family.
messages: Important role in the capacity of milk to transport calcium phosphate.
messages: Secreted

230844:LOC102918981
gene id: 230844:LOC102918981
uniprot id: A0A6J0CTY0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:LOC102919137
gene id: 230844:LOC102919137
uniprot id: A0A6I9MBJ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:LOC102923880
gene id: 230844:LOC102923880
uniprot id: A0A6I9LYQ3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 2H phosphoesterase superfamily. CNPase family.
messages: Exists as monomers and homodimers.
messages: May participate in RNA metabolism in the myelinating cell, CNP is the third most abundant protein in central nervous system myelin.
messages: Melanosome
messages: Membrane

230844:LOC102903048
gene id: 230844:LOC102903048
uniprot id: A0A6I9LWG0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Slco2a1
gene id: 230844:Slco2a1
uniprot id: A0A6I9LKN2
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the organo anion transporter (TC 2.A.60) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

230844:Alg9
gene id: 230844:Alg9
uniprot id: A0A6J0CGR2
uniprot id: A0A6J0CI62
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 22 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

230844:LOC102909838
gene id: 230844:LOC102909838
uniprot id: A0A6I9M7I5
names: Subcellular Location Annotation
messages: Nucleus

230844:Emsy
gene id: 230844:Emsy
uniprot id: A0A6I9LNB3
names: Subcellular Location Annotation
messages: Nucleus

230844:Zkscan5
gene id: 230844:Zkscan5
uniprot id: A0A6I9LH00
uniprot id: A0A6J0DPJ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the krueppel C2H2-type zinc-finger protein family.
messages: Nucleus

230844:Gpr15
gene id: 230844:Gpr15
uniprot id: A0A6I9MK15
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

230844:Dolk
gene id: 230844:Dolk
uniprot id: A0A6I9LQX1
names: Similarity
messages: Belongs to the polyprenol kinase family.

230844:Trpv4
gene id: 230844:Trpv4
uniprot id: A0A6I9M7R5
names: Subcellular Location Annotation
messages: Membrane

230844:LOC102911743
gene id: 230844:LOC102911743
uniprot id: A0A6I9M6E2
names: Subcellular Location Annotation
messages: Membrane

230844:LOC102926827
gene id: 230844:LOC102926827
uniprot id: A0A6I9LBS3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:LOC102904978
gene id: 230844:LOC102904978
uniprot id: A0A6I9LVI2
names: Subcellular Location Annotation
messages: Golgi apparatus membrane
messages: Membrane

230844:Cetn1
gene id: 230844:Cetn1
uniprot id: A0A6I9MHI0
names: Similarity
messages: Belongs to the centrin family.

230844:Il17rc
gene id: 230844:Il17rc
uniprot id: A0A6I9MDD2
uniprot id: A0A6J0CKF7
names: Subcellular Location Annotation
messages: Membrane

230844:Lamp5
gene id: 230844:Lamp5
uniprot id: A0A6I9LJM2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LAMP family.
messages: Endosome membrane
messages: Membrane

230844:Dyrk3
gene id: 230844:Dyrk3
uniprot id: A0A6I9MJR1
names: Similarity
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MNB/DYRK subfamily.

230844:Xcr1
gene id: 230844:Xcr1
uniprot id: A0A6I9M722
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

230844:Kdm5c
gene id: 230844:Kdm5c
uniprot id: A0A6I9M0P5
uniprot id: A0A6I9M7V1
uniprot id: A0A6I9MC09
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the JARID1 histone demethylase family.
messages: Nucleus

230844:Xylt2
gene id: 230844:Xylt2
uniprot id: A0A6I9L2Q4
uniprot id: A0A6J0E8Z8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycosyltransferase 14 family. XylT subfamily.
messages: Golgi apparatus membrane
messages: Membrane
messages: Monomer.

230844:Lzic
gene id: 230844:Lzic
uniprot id: A0A6I9L1K1
names: Similarity
messages: Belongs to the CTNNBIP1 family.

230844:LOC102903992
gene id: 230844:LOC102903992
uniprot id: A0A6I9MCG2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Belongs to the chemokine-like receptor (CMKLR) family.
messages: Membrane

230844:Nmnat3
gene id: 230844:Nmnat3
uniprot id: A0A6I9LD03
names: Similarity
messages: Belongs to the eukaryotic NMN adenylyltransferase family.

230844:Tor4a
gene id: 230844:Tor4a
uniprot id: A0A6I9LRD8
names: Similarity
messages: Belongs to the ClpA/ClpB family. Torsin subfamily.

230844:Tp53i11
gene id: 230844:Tp53i11
uniprot id: A0A6I9M381
uniprot id: A0A6J0CRV1
names: Subcellular Location Annotation
messages: Membrane

230844:Znf75a
gene id: 230844:Znf75a
uniprot id: A0A6J0DRY0
names: Subcellular Location Annotation
messages: Nucleus

230844:Inppl1
gene id: 230844:Inppl1
uniprot id: A0A6I9LZK8
uniprot id: A0A6I9MAL2
names: Similarity
names: Subcellular Location Annotation
messages: Basal cell membrane
messages: Belongs to the inositol 1,4,5-trisphosphate 5-phosphatase family.
messages: Membrane
messages: Nucleus speckle
messages: filopodium
messages: lamellipodium
messages: spindle pole

230844:Ppp1r15a
gene id: 230844:Ppp1r15a
uniprot id: A0A6I9LP66
names: Similarity
messages: Belongs to the PPP1R15 family.

230844:LOC102918676
gene id: 230844:LOC102918676
uniprot id: A0A6I9LMJ1
uniprot id: A0A6J0DF52
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane
messages: Mitochondrion inner membrane

230844:Hfe
gene id: 230844:Hfe
uniprot id: A0A6I9LZE2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MHC class I family.
messages: Membrane

230844:Gal3st3
gene id: 230844:Gal3st3
uniprot id: A0A6I9LKQ7
names: Similarity
messages: Belongs to the galactose-3-O-sulfotransferase family.

230844:LOC102908140
gene id: 230844:LOC102908140
uniprot id: A0A6I9MJT0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Gpr25
gene id: 230844:Gpr25
uniprot id: A0A6I9LUM5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

230844:Smarcal1
gene id: 230844:Smarcal1
uniprot id: A0A6I9L6D8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNF2/RAD54 helicase family. SMARCAL1 subfamily.
messages: Nucleus

230844:Prepl
gene id: 230844:Prepl
uniprot id: A0A6I9LMC9
uniprot id: A0A6I9M2P7
names: Similarity
messages: Belongs to the peptidase S9A family.

230844:Dnah5
gene id: 230844:Dnah5
uniprot id: A0A6I9LK07
names: Similarity
messages: Belongs to the dynein heavy chain family.

230844:Taf1b
gene id: 230844:Taf1b
uniprot id: A0A6I9L3Z2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRN7/TAF1B family.
messages: Component of RNA polymerase I core factor complex that acts as a GTF2B/TFIIB-like factor and plays a key role in multiple steps during transcription initiation such as pre-initiation complex (PIC) assembly and postpolymerase recruitment events in polymerase I (Pol I) transcription. Binds rDNA promoters and plays a role in Pol I recruitment as a component of the SL1/TIF-IB complex and, possibly, directly through its interaction with RRN3.
messages: nucleolus

230844:Dhdds
gene id: 230844:Dhdds
uniprot id: A0A6I9L293
uniprot id: A0A6I9LA98
names: Similarity
messages: Belongs to the UPP synthase family.

230844:Ska1
gene id: 230844:Ska1
uniprot id: A0A6I9KYP3
names: Similarity
messages: Belongs to the SKA1 family.

230844:Chsy3
gene id: 230844:Chsy3
uniprot id: A0A6I9LZ01
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chondroitin N-acetylgalactosaminyltransferase family.
messages: Golgi stack membrane
messages: Membrane

230844:Galnt11
gene id: 230844:Galnt11
uniprot id: A0A6I9M2W4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
messages: Golgi apparatus membrane
messages: Membrane

230844:LOC102907632
gene id: 230844:LOC102907632
uniprot id: A0A6I9M849
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Ifi44
gene id: 230844:Ifi44
uniprot id: A0A6I9M8P5
names: Similarity
messages: Belongs to the IFI44 family.

230844:Nuf2
gene id: 230844:Nuf2
uniprot id: A0A6J0CLL4
names: Similarity
messages: Belongs to the NUF2 family.

230844:LOC102907306
gene id: 230844:LOC102907306
uniprot id: A0A6I9LF89
names: Similarity
messages: Belongs to the LCE family.

230844:LOC102916868
gene id: 230844:LOC102916868
uniprot id: A0A6I9M501
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:LOC102910742
gene id: 230844:LOC102910742
uniprot id: A0A6I9M5C9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Eif4h
gene id: 230844:Eif4h
uniprot id: A0A6I9KUI7
names: Function
names: Subcellular Location Annotation
messages: Stimulates the RNA helicase activity of EIF4A in the translation initiation complex. Binds weakly mRNA.
messages: perinuclear region

230844:Ano4
gene id: 230844:Ano4
uniprot id: A0A6J0DE05
uniprot id: A0A6J0DFZ9
uniprot id: A0A6J0DGJ7
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anoctamin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

230844:LOC102907477
gene id: 230844:LOC102907477
uniprot id: A0A6J0EII3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Slc5a10
gene id: 230844:Slc5a10
uniprot id: A0A6J0CZ76
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Cell membrane
messages: Membrane

230844:Necap2
gene id: 230844:Necap2
uniprot id: A0A6I9L2N0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NECAP family.
messages: Involved in endocytosis.
messages: clathrin-coated vesicle membrane

230844:Stra6
gene id: 230844:Stra6
uniprot id: A0A6I9L4M9
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

230844:Nmbr
gene id: 230844:Nmbr
uniprot id: A0A6I9L411
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:LOC102924596
gene id: 230844:LOC102924596
uniprot id: A0A6I9KYV5
names: Caution
names: Cofactor
names: Similarity
messages: Belongs to the lipoxygenase family.
messages: Binds 1 Fe cation per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

230844:Grk4
gene id: 230844:Grk4
uniprot id: A0A6I9LKK5
uniprot id: A0A6I9LN54
uniprot id: A0A6I9LVP3
uniprot id: A0A6I9LVY2
uniprot id: A0A6J0DU82
uniprot id: A0A6J0DVJ2
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily.

230844:Mpl
gene id: 230844:Mpl
uniprot id: A0A6I9M811
uniprot id: A0A6I9MEW4
names: Similarity
messages: Belongs to the type I cytokine receptor family. Type 1 subfamily.

230844:Adcy6
gene id: 230844:Adcy6
uniprot id: A0A6I9L091
uniprot id: A0A6J0D075
uniprot id: A0A6J0D1N7
uniprot id: A0A6J0D4W4
uniprot id: A0A6J0D4X0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
messages: Binds 2 magnesium ions per subunit. Is also active with manganese (in vitro).
messages: Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.
messages: Membrane

230844:Rarres2
gene id: 230844:Rarres2
uniprot id: A0A6I9M3A2
names: Subcellular Location Annotation
messages: Secreted

230844:LOC102908155
gene id: 230844:LOC102908155
uniprot id: A0A6I9LM73
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Trmt2b
gene id: 230844:Trmt2b
uniprot id: A0A6J0E533
names: Caution
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

230844:Popdc2
gene id: 230844:Popdc2
uniprot id: A0A6I9L2F1
uniprot id: A0A6I9LE69
names: Similarity
messages: Belongs to the popeye family.

230844:LOC102905355
gene id: 230844:LOC102905355
uniprot id: A0A6I9L2R4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eIF-2B alpha/beta/delta subunits family.
messages: Catalyzes the exchange of eukaryotic initiation factor 2-bound GDP for GTP.
messages: Complex of five different subunits; alpha, beta, gamma, delta and epsilon.

230844:LOC102922620
gene id: 230844:LOC102922620
uniprot id: A0A6I9M5W6
uniprot id: A0A6J0E8A3
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

230844:LOC102921430
gene id: 230844:LOC102921430
uniprot id: A0A6I9MMG0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Celsr3
gene id: 230844:Celsr3
uniprot id: A0A6J0DBX5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 2 family. LN-TM7 subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Receptor that may have an important role in cell/cell signaling during nervous system formation.

230844:Spin2b
gene id: 230844:Spin2b
uniprot id: A0A6I9MGM2
names: Similarity
messages: Belongs to the SPIN/STSY family.

230844:Ddx31
gene id: 230844:Ddx31
uniprot id: A0A6I9LWE8
names: Domain
names: Function
names: Similarity
messages: Belongs to the DEAD box helicase family.
messages: RNA helicase.
messages: The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.

230844:Prps1
gene id: 230844:Prps1
uniprot id: A0A6I9KSI8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family.
messages: Catalyzes the synthesis of phosphoribosylpyrophosphate (PRPP) that is essential for nucleotide synthesis.
messages: Homodimer. The active form is probably a hexamer composed of 3 homodimers.

230844:LOC102920612
gene id: 230844:LOC102920612
uniprot id: A0A6I9MMG7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Cr1l
gene id: 230844:Cr1l
uniprot id: A0A6I9LQR3
uniprot id: A0A6I9LY89
uniprot id: A0A6J0E5V8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

230844:Brs3
gene id: 230844:Brs3
uniprot id: A0A6I9MD70
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Interacts with C6orf89.
messages: Membrane

230844:Thrap3
gene id: 230844:Thrap3
uniprot id: A0A6I9LP11
names: Similarity
messages: Belongs to the BCLAF1/THRAP3 family.

230844:Agl
gene id: 230844:Agl
uniprot id: A0A6I9L7F0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycogen debranching enzyme family.
messages: Cytoplasm
messages: Multifunctional enzyme acting as 1,4-alpha-D-glucan:1,4-alpha-D-glucan 4-alpha-D-glycosyltransferase and amylo-1,6-glucosidase in glycogen degradation.

230844:LOC102923164
gene id: 230844:LOC102923164
uniprot id: A0A6I9MB54
names: Subcellular Location Annotation
messages: Membrane

230844:Plscr3
gene id: 230844:Plscr3
uniprot id: A0A6J0CX62
names: Function
names: Similarity
messages: Belongs to the phospholipid scramblase family.
messages: May mediate accelerated ATP-independent bidirectional transbilayer migration of phospholipids upon binding calcium ions that results in a loss of phospholipid asymmetry in the plasma membrane.

230844:LOC102921823
gene id: 230844:LOC102921823
uniprot id: A0A6J0D0H5
names: Similarity
names: Subunit
messages: Belongs to the histone H3 family.
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

230844:Rrp15
gene id: 230844:Rrp15
uniprot id: A0A6I9KW76
names: Similarity
messages: Belongs to the RRP15 family.

230844:Slc17a6
gene id: 230844:Slc17a6
uniprot id: A0A6J0E8F9
names: Subcellular Location Annotation
messages: Membrane

230844:LOC102909251
gene id: 230844:LOC102909251
uniprot id: A0A6I9L0T7
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL33 family.

230844:Cntnap1
gene id: 230844:Cntnap1
uniprot id: A0A6I9M5B4
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the neurexin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: paranodal septate junction

230844:LOC102916325
gene id: 230844:LOC102916325
uniprot id: A0A6I9LUW0
names: Subcellular Location Annotation
messages: Nucleus speckle
messages: nucleoplasm

230844:Trmt1l
gene id: 230844:Trmt1l
uniprot id: A0A6I9LA20
uniprot id: A0A6I9LJX8
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. Trm1 family.
messages: May play a role in motor coordination and exploratory behavior.

230844:Ddt
gene id: 230844:Ddt
uniprot id: A0A6I9LH54
names: Similarity
messages: Belongs to the MIF family.

230844:Mtch2
gene id: 230844:Mtch2
uniprot id: A0A6I9LTQ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

230844:LOC102920512
gene id: 230844:LOC102920512
uniprot id: A0A6I9MNI2
names: Cofactor
names: Similarity
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.

230844:Rad9a
gene id: 230844:Rad9a
uniprot id: A0A6I9LB65
names: Similarity
messages: Belongs to the rad9 family.

230844:Sgk2
gene id: 230844:Sgk2
uniprot id: A0A6I9L0F2
names: Similarity
messages: Belongs to the protein kinase superfamily.

230844:Vcl
gene id: 230844:Vcl
uniprot id: A0A6I9LJ23
uniprot id: A0A6I9LTN5
uniprot id: A0A6I9LYW0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Actin filament (F-actin)-binding protein involved in cell-matrix adhesion and cell-cell adhesion. Regulates cell-surface E-cadherin expression and potentiates mechanosensing by the E-cadherin complex. May also play important roles in cell morphology and locomotion.
messages: Belongs to the vinculin/alpha-catenin family.
messages: Cell membrane
messages: Membrane
messages: adherens junction
messages: podosome

230844:Il18r1
gene id: 230844:Il18r1
uniprot id: A0A6J0DN40
names: Similarity
messages: Belongs to the interleukin-1 receptor family.

230844:LOC102923765
gene id: 230844:LOC102923765
uniprot id: A0A6I9M4L2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Uba5
gene id: 230844:Uba5
uniprot id: A0A6I9LH48
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ubiquitin-activating E1 family. UBA5 subfamily.
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus

230844:Mtor
gene id: 230844:Mtor
uniprot id: A0A6I9LD53
names: Similarity
messages: Belongs to the PI3/PI4-kinase family.

230844:Arl5c
gene id: 230844:Arl5c
uniprot id: A0A6I9KW67
names: Similarity
messages: Belongs to the small GTPase superfamily. Arf family.

230844:Sgcd
gene id: 230844:Sgcd
uniprot id: A0A6J0E6P9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sarcoglycan beta/delta/gamma/zeta family.
messages: cytoskeleton
messages: sarcolemma

230844:LOC102924651
gene id: 230844:LOC102924651
uniprot id: A0A6I9LSE8
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the alkaline phosphatase family.
messages: Binds 1 Mg(2+) ion.
messages: Binds 2 Zn(2+) ions.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

230844:LOC102908048
gene id: 230844:LOC102908048
uniprot id: A0A6I9LV00
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Kcna2
gene id: 230844:Kcna2
uniprot id: A0A6I9LI04
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the potassium channel family. A (Shaker) (TC 1.A.1.2) subfamily. Kv1.2/KCNA2 sub-subfamily.
messages: Cell membrane
messages: Membrane
messages: Presynaptic cell membrane
messages: Synaptic cell membrane
messages: lamellipodium membrane
messages: paranodal septate junction
messages: synaptosome

230844:LOC102920301
gene id: 230844:LOC102920301
uniprot id: A0A6I9M658
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Guk1
gene id: 230844:Guk1
uniprot id: A0A6I9MN89
names: Similarity
messages: Belongs to the guanylate kinase family.

230844:Hoxa9
gene id: 230844:Hoxa9
uniprot id: A0A6J0DMN2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Abd-B homeobox family.
messages: Nucleus
messages: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

230844:Mmel1
gene id: 230844:Mmel1
uniprot id: A0A6I9MAX9
uniprot id: A0A6J0CE39
uniprot id: A0A6J0CFT7
uniprot id: A0A6J0CG82
names: Subcellular Location Annotation
messages: Membrane

230844:Dhx58
gene id: 230844:Dhx58
uniprot id: A0A6I9M585
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the helicase family. RLR subfamily.
messages: Cytoplasm

230844:Lama4
gene id: 230844:Lama4
uniprot id: A0A6J0DZ73
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: basement membrane

230844:Senp1
gene id: 230844:Senp1
uniprot id: A0A6J0D0M4
uniprot id: A0A6J0D1D1
uniprot id: A0A6J0D233
names: Similarity
messages: Belongs to the peptidase C48 family.

230844:Gnb5
gene id: 230844:Gnb5
uniprot id: A0A6I9L9T6
names: Similarity
messages: Belongs to the WD repeat G protein beta family.

230844:Erf
gene id: 230844:Erf
uniprot id: A0A6I9M627
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

230844:LOC102928420
gene id: 230844:LOC102928420
uniprot id: A0A6J0DED7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mitochondrion
messages: Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP.
messages: Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis.

230844:LOC102923839
gene id: 230844:LOC102923839
uniprot id: A0A6I9LGT7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RFamide neuropeptide family.
messages: Secreted

230844:Glce
gene id: 230844:Glce
uniprot id: A0A6I9L1A4
names: Similarity
messages: Belongs to the D-glucuronyl C5-epimerase family.

230844:Emc4
gene id: 230844:Emc4
uniprot id: A0A6I9LY98
uniprot id: A0A6I9MEH6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EMC4 family.
messages: Component of the ER membrane protein complex (EMC).
messages: Endoplasmic reticulum membrane
messages: Membrane

230844:Nrg4
gene id: 230844:Nrg4
uniprot id: A0A6I9KVF2
names: Caution
names: Similarity
messages: Belongs to the neuregulin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

230844:Gpr152
gene id: 230844:Gpr152
uniprot id: A0A6I9LB55
names: Subcellular Location Annotation
messages: Membrane

230844:Ggt7
gene id: 230844:Ggt7
uniprot id: A0A6I9M2K2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyltransferase family.
messages: Cleaves the gamma-glutamyl peptide bond of glutathione and glutathione conjugates.
messages: Membrane

230844:Myrf
gene id: 230844:Myrf
uniprot id: A0A6J0CJ73
uniprot id: A0A6J0CJU7
uniprot id: A0A6J0CMF1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MRF family.
messages: Membrane

230844:LOC102914937
gene id: 230844:LOC102914937
uniprot id: A0A6I9MMZ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MHC class II family.
messages: Membrane

230844:LOC102904968
gene id: 230844:LOC102904968
uniprot id: A0A6I9LP59
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2A family.
messages: Chromosome
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

230844:Slc5a6
gene id: 230844:Slc5a6
uniprot id: A0A6J0CS97
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Cell membrane
messages: Membrane

230844:Ap4m1
gene id: 230844:Ap4m1
uniprot id: A0A6I9KUA1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adaptor complexes medium subunit family.
messages: Component of the adaptor protein complex 4 (AP-4). Adaptor protein complexes are vesicle coat components involved both in vesicle formation and cargo selection. They control the vesicular transport of proteins in different trafficking pathways. AP-4 forms a non clathrin-associated coat on vesicles departing the trans-Golgi network (TGN) and may be involved in the targeting of proteins from the trans-Golgi network (TGN) to the endosomal-lysosomal system. It is also involved in protein sorting to the basolateral membrane in epithelial cells and the proper asymmetric localization of somatodendritic proteins in neurons. Within AP-4, the mu-type subunit AP4M1 is directly involved in the recognition and binding of tyrosine-based sorting signals found in the cytoplasmic part of cargos. The adaptor protein complex 4 (AP-4) may also recognize other types of sorting signal.
messages: Early endosome
messages: trans-Golgi network membrane

230844:LOC102917968
gene id: 230844:LOC102917968
uniprot id: A0A6I9LSP2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UDP-glycosyltransferase family.
messages: Membrane

230844:LOC102913057
gene id: 230844:LOC102913057
uniprot id: A0A6I9MKU1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UQCRQ/QCR8 family.
messages: Component of the ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII), a multisubunit enzyme composed of 11 subunits. The complex is composed of 3 respiratory subunits cytochrome b, cytochrome c1 and Rieske protein UQCRFS1, 2 core protein subunits UQCRC1/QCR1 and UQCRC2/QCR2, and 6 low-molecular weight protein subunits UQCRH/QCR6, UQCRB/QCR7, UQCRQ/QCR8, UQCR10/QCR9, UQCR11/QCR10 and subunit 9, the cleavage product of Rieske protein UQCRFS1. The complex exists as an obligatory dimer and forms supercomplexes (SCs) in the inner mitochondrial membrane with NADH-ubiquinone oxidoreductase (complex I, CI) and cytochrome c oxidase (complex IV, CIV), resulting in different assemblies (supercomplex SCI(1)III(2)IV(1) and megacomplex MCI(2)III(2)IV(2)). Interacts with UQCC6.
messages: Component of the ubiquinol-cytochrome c oxidoreductase, a multisubunit transmembrane complex that is part of the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. The cytochrome b-c1 complex catalyzes electron transfer from ubiquinol to cytochrome c, linking this redox reaction to translocation of protons across the mitochondrial inner membrane, with protons being carried across the membrane as hydrogens on the quinol. In the process called Q cycle, 2 protons are consumed from the matrix, 4 protons are released into the intermembrane space and 2 electrons are passed to cytochrome c.
messages: Membrane
messages: Mitochondrion inner membrane

230844:Usp22
gene id: 230844:Usp22
uniprot id: A0A6I9L628
names: Function
names: Similarity
messages: Belongs to the peptidase C19 family.
messages: Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes.

230844:Mmp17
gene id: 230844:Mmp17
uniprot id: A0A6I9KUL9
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M10A family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Can bind about 5 Ca(2+) ions per subunit.

230844:LOC102915365
gene id: 230844:LOC102915365
uniprot id: A0A6J0DGK9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PARI family.
messages: Cytoplasm
messages: Nucleus

230844:Dnmt1
gene id: 230844:Dnmt1
uniprot id: A0A6I9LZE8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.
messages: Nucleus

230844:Ndel1
gene id: 230844:Ndel1
uniprot id: A0A6I9KYS4
uniprot id: A0A6J0CXA7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nudE family.
messages: centrosome
messages: kinetochore
messages: spindle

230844:Pus7l
gene id: 230844:Pus7l
uniprot id: A0A6I9L079
uniprot id: A0A6J0CZP0
uniprot id: A0A6J0D186
names: Similarity
messages: Belongs to the pseudouridine synthase TruD family.

230844:Bcap29
gene id: 230844:Bcap29
uniprot id: A0A6J0E4W8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BCAP29/BCAP31 family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Plays a role in the export of secreted proteins in the ER.

230844:LOC102918573
gene id: 230844:LOC102918573
uniprot id: A0A6I9MKV3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Membrane
messages: tight junction

230844:LOC102902775
gene id: 230844:LOC102902775
uniprot id: A0A6I9MAM0
names: Similarity
messages: Belongs to the Nudix hydrolase family. DIPP subfamily.

230844:Pcsk7
gene id: 230844:Pcsk7
uniprot id: A0A6I9M3X8
uniprot id: A0A6J0E7E5
names: Similarity
messages: Belongs to the peptidase S8 family.

230844:Tgfbi
gene id: 230844:Tgfbi
uniprot id: A0A6I9LGH1
names: Subcellular Location Annotation
messages: extracellular matrix

230844:Ppp1r9a
gene id: 230844:Ppp1r9a
uniprot id: A0A6I9M3F0
uniprot id: A0A6J0E155
names: Subcellular Location Annotation
messages: cytoskeleton

230844:LOC102908745
gene id: 230844:LOC102908745
uniprot id: A0A6I9LC00
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the calcitonin family.
messages: Interacts with IDE and INS.
messages: Secreted
messages: Selectively inhibits insulin-stimulated glucose utilization and glycogen deposition in muscle, while not affecting adipocyte glucose metabolism.

230844:Aldoa
gene id: 230844:Aldoa
uniprot id: A0A6I9LDD9
names: Similarity
messages: Belongs to the class I fructose-bisphosphate aldolase family.

230844:Glra3
gene id: 230844:Glra3
uniprot id: A0A6I9L0D7
uniprot id: A0A6J0DE30
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synapse
messages: Synaptic cell membrane

230844:Manf
gene id: 230844:Manf
uniprot id: A0A6I9LFT2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ARMET family.
messages: Secreted

230844:LOC102911701
gene id: 230844:LOC102911701
uniprot id: A0A6I9M5V7
names: Similarity
names: Subunit
messages: Belongs to the histone H3 family.
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

230844:Tspo
gene id: 230844:Tspo
uniprot id: A0A6I9LPE0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TspO/BZRP family.
messages: Membrane

230844:Trpt1
gene id: 230844:Trpt1
uniprot id: A0A6J0DNV5
names: Function
names: Similarity
messages: Belongs to the KptA/TPT1 family.
messages: Catalyzes the last step of tRNA splicing, the transfer of the splice junction 2'-phosphate from ligated tRNA to NAD to produce ADP-ribose 1''-2'' cyclic phosphate.

230844:Btbd10
gene id: 230844:Btbd10
uniprot id: A0A6I9LKJ9
uniprot id: A0A6J0DB33
uniprot id: A0A6J0DDC2
names: Subcellular Location Annotation
messages: Cytoplasm

230844:Glp2r
gene id: 230844:Glp2r
uniprot id: A0A6I9L991
names: Subcellular Location Annotation
messages: Membrane

230844:Dsg2
gene id: 230844:Dsg2
uniprot id: A0A6I9KYM7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: desmosome

230844:Txk
gene id: 230844:Txk
uniprot id: A0A6J0DFM5
names: Similarity
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.

230844:LOC102903114
gene id: 230844:LOC102903114
uniprot id: A0A6I9LMG7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C1 family.
messages: Lysosome

230844:LOC102917266
gene id: 230844:LOC102917266
uniprot id: A0A6I9M5K3
uniprot id: A0A6J0E0P7
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by ADP, AMP, or fructose 2,6-bisphosphate, and allosterically inhibited by ATP or citrate.
messages: Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade "E" sub-subfamily.
messages: Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homo- and heterotetramers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

230844:Slco3a1
gene id: 230844:Slco3a1
uniprot id: A0A6I9M0G1
uniprot id: A0A6I9M623
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the organo anion transporter (TC 2.A.60) family.
messages: Cell membrane
messages: Membrane

230844:Mcrip2
gene id: 230844:Mcrip2
uniprot id: A0A6I9L9B8
uniprot id: A0A6J0DIS4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MCRIP family.
messages: Nucleus
messages: Stress granule

230844:Kcnh5
gene id: 230844:Kcnh5
uniprot id: A0A6I9L567
names: Subcellular Location Annotation
messages: Membrane

230844:Atp6v0b
gene id: 230844:Atp6v0b
uniprot id: A0A6I9MLG6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the V-ATPase proteolipid subunit family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Proton-conducting pore forming of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment.
messages: V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex. The V1 complex consists of three catalytic AB heterodimers that form a heterohexamer, three peripheral stalks each consisting of EG heterodimers, one central rotor including subunits D and F, and the regulatory subunits C and H. The proton translocation complex V0 consists of the proton transport subunit a, a ring of proteolipid subunits c9c'', rotary subunit d, subunits e and f, and the accessory subunits.
messages: clathrin-coated vesicle membrane

230844:Prrt2
gene id: 230844:Prrt2
uniprot id: A0A6I9LDC1
names: Similarity
messages: Belongs to the CD225/Dispanin family.

230844:Hcrtr1
gene id: 230844:Hcrtr1
uniprot id: A0A6I9L235
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Siah2
gene id: 230844:Siah2
uniprot id: A0A6J0CM55
names: Domain
names: Function
names: Similarity
messages: Belongs to the SINA (Seven in absentia) family.
messages: E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.
messages: The RING-type zinc finger domain is essential for ubiquitin ligase activity.
messages: The SBD domain (substrate-binding domain) mediates the interaction with substrate proteins. It is related to the TRAF family.

230844:Myo1g
gene id: 230844:Myo1g
uniprot id: A0A6I9L4K5
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.

230844:Kif13a
gene id: 230844:Kif13a
uniprot id: A0A6I9KXC4
uniprot id: A0A6I9L488
uniprot id: A0A6J0CUU2
uniprot id: A0A6J0CVS6
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

230844:LOC102915139
gene id: 230844:LOC102915139
uniprot id: A0A6I9L3T5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EAF7 family.
messages: Nucleus

230844:Mal
gene id: 230844:Mal
uniprot id: A0A6I9LXI6
names: Subcellular Location Annotation
messages: Membrane

230844:Slc2a4
gene id: 230844:Slc2a4
uniprot id: A0A6I9KYD8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. Glucose transporter subfamily.
messages: Cell membrane
messages: Endomembrane system
messages: Membrane
messages: perinuclear region

230844:Dmbx1
gene id: 230844:Dmbx1
uniprot id: A0A6I9LMH4
names: Subcellular Location Annotation
messages: Nucleus

230844:Timm10b
gene id: 230844:Timm10b
uniprot id: A0A6I9M7K2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the small Tim family.
messages: Heterohexamer.
messages: Mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space.
messages: Mitochondrion inner membrane
messages: The twin CX3C motif contains 4 conserved Cys residues that form 2 disulfide bonds in the mitochondrial intermembrane space.

230844:Rbbp5
gene id: 230844:Rbbp5
uniprot id: A0A6I9LVH4
uniprot id: A0A6I9M3J3
names: Subcellular Location Annotation
messages: Nucleus

230844:Tmco1
gene id: 230844:Tmco1
uniprot id: A0A6I9LRM3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TMCO1 family.
messages: Calcium-selective channel required to prevent calcium stores from overfilling.
messages: Endoplasmic reticulum membrane
messages: Homodimer and homotetramer. Homodimer under resting conditions; forms homotetramers following and ER calcium overload.
messages: Membrane

230844:Ckap2l
gene id: 230844:Ckap2l
uniprot id: A0A6I9M6J1
names: Similarity
messages: Belongs to the CKAP2 family.

230844:Foxr1
gene id: 230844:Foxr1
uniprot id: A0A6I9LZR8
names: Subcellular Location Annotation
messages: Nucleus

230844:LOC102912080
gene id: 230844:LOC102912080
uniprot id: A0A6J0CHX9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Interacts with IL8. Interacts with GNAI2.
messages: Membrane

230844:Scn1b
gene id: 230844:Scn1b
uniprot id: A0A6I9LE70
names: Subcellular Location Annotation
messages: Membrane

230844:Phactr4
gene id: 230844:Phactr4
uniprot id: A0A6J0D3A9
uniprot id: A0A6J0D984
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphatase and actin regulator family.
messages: Binds PPP1CA and actin.
messages: Cytoplasm
messages: Regulator of protein phosphatase 1 (PP1) required for neural tube and optic fissure closure, and enteric neural crest cell (ENCCs) migration during development. Acts as an activator of PP1. During neural tube closure, localizes to the ventral neural tube and activates PP1, leading to down-regulate cell proliferation within cranial neural tissue and the neural retina. Also acts as a regulator of migration of enteric neural crest cells (ENCCs) by activating PP1, leading to repression of the integrin signaling through the rho/rock pathway.
messages: lamellipodium

230844:Spock3
gene id: 230844:Spock3
uniprot id: A0A6J0E325
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

230844:Tyw3
gene id: 230844:Tyw3
uniprot id: A0A6I9L1I1
names: Function
names: Similarity
messages: Belongs to the TYW3 family.
messages: Probable S-adenosyl-L-methionine-dependent methyltransferase that acts as a component of the wybutosine biosynthesis pathway. Wybutosine is a hyper modified guanosine with a tricyclic base found at the 3'-position adjacent to the anticodon of eukaryotic phenylalanine tRNA.

230844:Tlcd3a
gene id: 230844:Tlcd3a
uniprot id: A0A6I9L6J1
names: Subcellular Location Annotation
messages: Membrane

230844:Speg
gene id: 230844:Speg
uniprot id: A0A6I9L2N3
uniprot id: A0A6J0EAU5
uniprot id: A0A6J0EGK7
names: Similarity
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family.

230844:LOC102916196
gene id: 230844:LOC102916196
uniprot id: A0A6I9LLC6
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

230844:Daxx
gene id: 230844:Daxx
uniprot id: A0A6J0CQL9
uniprot id: A0A6J0CSR9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DAXX family.
messages: Cytoplasm
messages: PML body
messages: centromere
messages: nucleolus
messages: nucleoplasm

230844:LOC102906547
gene id: 230844:LOC102906547
uniprot id: A0A6I9LPY0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COA8 family.
messages: Mitochondrion inner membrane

230844:Celf4
gene id: 230844:Celf4
uniprot id: A0A6I9KUN6
uniprot id: A0A6I9KV51
uniprot id: A0A6I9L167
uniprot id: A0A6I9L1F6
uniprot id: A0A6I9L4F5
uniprot id: A0A6J0DRI3
uniprot id: A0A6J0DU68
uniprot id: A0A6J0DUY0
uniprot id: A0A6J0DZZ2
uniprot id: A0A6J0DZZ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CELF/BRUNOL family.
messages: Nucleus

230844:Lamb2
gene id: 230844:Lamb2
uniprot id: A0A6I9L8B7
uniprot id: A0A6J0DBM8
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: basement membrane

230844:Fat1
gene id: 230844:Fat1
uniprot id: A0A6J0DEV9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

230844:Dnm2
gene id: 230844:Dnm2
uniprot id: A0A6I9LN43
uniprot id: A0A6I9LN48
uniprot id: A0A6I9LRA1
uniprot id: A0A6I9LYP8
uniprot id: A0A6I9LZB7
uniprot id: A0A6I9M3P4
uniprot id: A0A6I9M3Q2
uniprot id: A0A6J0DYD2
names: Similarity
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.

230844:LOC102926273
gene id: 230844:LOC102926273
uniprot id: A0A6I9M2D3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Hck
gene id: 230844:Hck
uniprot id: A0A6I9LMX1
names: Similarity
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.

230844:LOC102928593
gene id: 230844:LOC102928593
uniprot id: A0A6I9MIG6
names: Similarity
messages: Belongs to the PRAME family.

230844:Mrps24
gene id: 230844:Mrps24
uniprot id: A0A6I9KXV6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Mitochondrion

230844:Nln
gene id: 230844:Nln
uniprot id: A0A6I9LFE0
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

230844:Eif5a2
gene id: 230844:Eif5a2
uniprot id: A0A6I9KU75
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eIF-5A family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Translation factor that promotes translation elongation and termination, particularly upon ribosome stalling at specific amino acid sequence contexts. Binds between the exit (E) and peptidyl (P) site of the ribosome and promotes rescue of stalled ribosome: specifically required for efficient translation of polyproline-containing peptides as well as other motifs that stall the ribosome. Acts as ribosome quality control (RQC) cofactor by joining the RQC complex to facilitate peptidyl transfer during CAT tailing step.
messages: eIF-5A seems to be the only eukaryotic protein to have a hypusine residue which is a post-translational modification of a lysine by the addition of a butylamino group.

230844:LOC102907526
gene id: 230844:LOC102907526
uniprot id: A0A6I9MD85
names: Function
names: Similarity
messages: Belongs to the ferritin family.
messages: Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation.

230844:Serpinb10
gene id: 230844:Serpinb10
uniprot id: A0A6I9M778
names: Similarity
messages: Belongs to the serpin family.

230844:Zfp36
gene id: 230844:Zfp36
uniprot id: A0A6I9LXH6
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Associates with the cytoplasmic CCR4-NOT deadenylase complex to trigger ARE-containing mRNA deadenylation and decay processes.
messages: Cytoplasm
messages: Nucleus
messages: Zinc-finger RNA-binding protein that destabilizes several cytoplasmic AU-rich element (ARE)-containing mRNA transcripts by promoting their poly(A) tail removal or deadenylation, and hence provide a mechanism for attenuating protein synthesis. Acts as a 3'-untranslated region (UTR) ARE mRNA-binding adapter protein to communicate signaling events to the mRNA decay machinery. Functions by recruiting the CCR4-NOT deadenylase complex and probably other components of the cytoplasmic RNA decay machinery to the bound ARE-containing mRNAs, and hence promotes ARE-mediated mRNA deadenylation and decay processes. Binds to 3'-UTR ARE of numerous mRNAs.

230844:Tmem255b
gene id: 230844:Tmem255b
uniprot id: A0A6I9LCM2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM255 family.
messages: Membrane

230844:LOC102903517
gene id: 230844:LOC102903517
uniprot id: A0A6I9LA73
names: Similarity
messages: Belongs to the cytochrome c oxidase VIIa family.

230844:Zic4
gene id: 230844:Zic4
uniprot id: A0A6J0E6A9
names: Similarity
messages: Belongs to the GLI C2H2-type zinc-finger protein family.

230844:Celf3
gene id: 230844:Celf3
uniprot id: A0A6I9M1Z8
uniprot id: A0A6I9M9I6
uniprot id: A0A6I9MDJ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CELF/BRUNOL family.
messages: Nucleus

230844:Eml6
gene id: 230844:Eml6
uniprot id: A0A6J0CHJ4
names: Function
names: Similarity
messages: Belongs to the WD repeat EMAP family.
messages: May modify the assembly dynamics of microtubules, such that microtubules are slightly longer, but more dynamic.

230844:Spaca5b
gene id: 230844:Spaca5b
uniprot id: A0A6I9LVZ1
names: Similarity
messages: Belongs to the glycosyl hydrolase 22 family.

230844:Rgs5
gene id: 230844:Rgs5
uniprot id: A0A6I9M144
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. Binds to G(i)-alpha and G(o)-alpha, but not to G(s)-alpha.

230844:Slc17a4
gene id: 230844:Slc17a4
uniprot id: A0A6J0CFV5
names: Subcellular Location Annotation
messages: Membrane

230844:Adam7
gene id: 230844:Adam7
uniprot id: A0A6I9M2E5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

230844:Erbb2
gene id: 230844:Erbb2
uniprot id: A0A6I9KVU0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. EGF receptor subfamily.
messages: Membrane

230844:Thbs4
gene id: 230844:Thbs4
uniprot id: A0A6I9LT97
names: Caution
names: Similarity
messages: Belongs to the thrombospondin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

230844:Gls2
gene id: 230844:Gls2
uniprot id: A0A6I9LNR6
uniprot id: A0A6I9M4H3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutaminase family.
messages: Mitochondrion

230844:Nup107
gene id: 230844:Nup107
uniprot id: A0A6I9L5K6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the nucleoporin Nup84/Nup107 family.
messages: Functions as a component of the nuclear pore complex (NPC).
messages: Nucleus membrane
messages: Part of the nuclear pore complex (NPC).
messages: nuclear pore complex

230844:LOC102923755
gene id: 230844:LOC102923755
uniprot id: A0A6I9KZG2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the somatotropin/prolactin family.
messages: Secreted

230844:Henmt1
gene id: 230844:Henmt1
uniprot id: A0A6I9LAN0
names: Similarity
messages: Belongs to the methyltransferase superfamily. HEN1 family.

230844:Traf6
gene id: 230844:Traf6
uniprot id: A0A6I9LHN6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TNF receptor-associated factor family. A subfamily.
messages: Lipid droplet
messages: Nucleus
messages: cell cortex

230844:Shmt1
gene id: 230844:Shmt1
uniprot id: A0A6I9KYY5
names: Function
names: Similarity
messages: Belongs to the SHMT family.
messages: Interconversion of serine and glycine.

230844:Tlr4
gene id: 230844:Tlr4
uniprot id: A0A6I9LMT8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Toll-like receptor family.
messages: Membrane

230844:Fgr
gene id: 230844:Fgr
uniprot id: A0A6I9L273
names: Similarity
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.

230844:Ca3
gene id: 230844:Ca3
uniprot id: A0A6J0CQ01
names: Function
names: Similarity
messages: Belongs to the alpha-carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

230844:Lhx1
gene id: 230844:Lhx1
uniprot id: A0A6I9LGA3
names: Subcellular Location Annotation
messages: Nucleus

230844:Ppp3r2
gene id: 230844:Ppp3r2
uniprot id: A0A6I9L604
names: Similarity
messages: Belongs to the calcineurin regulatory subunit family.

230844:Gpr119
gene id: 230844:Gpr119
uniprot id: A0A6I9MKF7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

230844:A3galt2
gene id: 230844:A3galt2
uniprot id: A0A6I9M4H7
uniprot id: A0A6I9MFP3
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 6 family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Membrane

230844:Slc4a2
gene id: 230844:Slc4a2
uniprot id: A0A6I9MCF4
uniprot id: A0A6J0CQ62
uniprot id: A0A6J0CRG5
names: Similarity
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Belongs to the anion exchanger (TC 2.A.31) family.
messages: Cell membrane
messages: Membrane

230844:Rorc
gene id: 230844:Rorc
uniprot id: A0A6I9M203
uniprot id: A0A6J0CN88
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR1 subfamily.
messages: Nucleus

230844:Tmem63c
gene id: 230844:Tmem63c
uniprot id: A0A6I9MAC1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CSC1 (TC 1.A.17) family.
messages: Membrane

230844:Srms
gene id: 230844:Srms
uniprot id: A0A6I9MIE6
names: Similarity
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.

230844:LOC102925552
gene id: 230844:LOC102925552
uniprot id: A0A6I9MIM9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome P450 family.
messages: Cytochromes P450 are a group of heme-thiolate monooxygenases.
messages: Endoplasmic reticulum membrane
messages: Microsome membrane

230844:C21H6orf89
gene id: 230844:C21H6orf89
uniprot id: A0A6I9LHR7
uniprot id: A0A6J0DQN9
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Golgi apparatus membrane
messages: Membrane

230844:Pik3ca
gene id: 230844:Pik3ca
uniprot id: A0A6J0DLL0
names: Similarity
messages: Belongs to the PI3/PI4-kinase family. Type III PI4K subfamily.

230844:Dgkg
gene id: 230844:Dgkg
uniprot id: A0A6I9LM17
uniprot id: A0A6J0E1E3
names: Similarity
messages: Belongs to the eukaryotic diacylglycerol kinase family.

230844:Cenpn
gene id: 230844:Cenpn
uniprot id: A0A6I9LXK0
names: Similarity
messages: Belongs to the CENP-N/CHL4 family.

230844:Rrs1
gene id: 230844:Rrs1
uniprot id: A0A6J0D698
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRS1 family.
messages: Involved in ribosomal large subunit assembly.
messages: Nucleus

230844:Erp29
gene id: 230844:Erp29
uniprot id: A0A6I9KZX4
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Does not seem to be a disulfide isomerase.
messages: Endoplasmic reticulum lumen
messages: Homodimer.
messages: Melanosome

230844:Evl
gene id: 230844:Evl
uniprot id: A0A6I9L255
uniprot id: A0A6J0DZ44
uniprot id: A0A6J0E758
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Ena/VASP family.
messages: Ena/VASP proteins are actin-associated proteins involved in a range of processes dependent on cytoskeleton remodeling and cell polarity such as axon guidance, lamellipodial and filopodial dynamics, platelet activation and cell migration.
messages: cytoskeleton

230844:Ccne2
gene id: 230844:Ccne2
uniprot id: A0A6I9L8T9
uniprot id: A0A6J0D2D7
names: Similarity
messages: Belongs to the cyclin family.

230844:Xkr5
gene id: 230844:Xkr5
uniprot id: A0A6I9M9Y6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the XK family.
messages: Membrane

230844:Med19
gene id: 230844:Med19
uniprot id: A0A6I9M903
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 19 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex, which is composed of MED1, MED4, MED6, MED7, MED8, MED9, MED10, MED11, MED12, MED13, MED13L, MED14, MED15, MED16, MED17, MED18, MED19, MED20, MED21, MED22, MED23, MED24, MED25, MED26, MED27, MED29, MED30, MED31, CCNC, CDK8 and CDC2L6/CDK11. The MED12, MED13, CCNC and CDK8 subunits form a distinct module termed the CDK8 module. Mediator containing the CDK8 module is less active than Mediator lacking this module in supporting transcriptional activation. Individual preparations of the Mediator complex lacking one or more distinct subunits have been variously termed ARC, CRSP, DRIP, PC2, SMCC and TRAP.
messages: Nucleus

230844:Lamp3
gene id: 230844:Lamp3
uniprot id: A0A6I9LZW9
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LAMP family.
messages: Endosome membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Lysosome membrane
messages: Membrane

230844:Aldh1a2
gene id: 230844:Aldh1a2
uniprot id: A0A6I9LIJ5
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

230844:Ptn
gene id: 230844:Ptn
uniprot id: A0A6I9MD11
names: Similarity
messages: Belongs to the pleiotrophin family.

230844:Entpd6
gene id: 230844:Entpd6
uniprot id: A0A6I9LKH5
names: Similarity
messages: Belongs to the GDA1/CD39 NTPase family.

230844:LOC102922505
gene id: 230844:LOC102922505
uniprot id: A0A6J0EF85
names: Similarity
messages: Belongs to the HIN-200 family.

230844:LOC102921978
gene id: 230844:LOC102921978
uniprot id: A0A6I9LP24
names: Subcellular Location Annotation
messages: Membrane

230844:Kcnj3
gene id: 230844:Kcnj3
uniprot id: A0A6I9L010
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associates with GIRK2, GIRK3 or GIRK4 to form a G-protein activated heteromultimer pore-forming unit. The resulting inward current is much larger.
messages: Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family. KCNJ3 subfamily.
messages: Membrane
messages: This potassium channel is controlled by G proteins. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. This receptor plays a crucial role in regulating the heartbeat.

230844:Adam10
gene id: 230844:Adam10
uniprot id: A0A6I9LM06
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

230844:Phf19
gene id: 230844:Phf19
uniprot id: A0A6I9M1R5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Polycomblike family.
messages: Nucleus

230844:Uchl3
gene id: 230844:Uchl3
uniprot id: A0A6I9LFI1
names: Similarity
messages: Belongs to the peptidase C12 family.

230844:LOC102915504
gene id: 230844:LOC102915504
uniprot id: A0A6I9M033
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Gpr50
gene id: 230844:Gpr50
uniprot id: A0A6I9L6S4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:LOC102921565
gene id: 230844:LOC102921565
uniprot id: A0A6I9M028
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial pyruvate carrier (MPC) (TC 2.A.105) family.
messages: Mediates the uptake of pyruvate into mitochondria.
messages: Membrane
messages: Mitochondrion inner membrane

230844:LOC102912376
gene id: 230844:LOC102912376
uniprot id: A0A6I9LYY6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
messages: Membrane

230844:Ca7
gene id: 230844:Ca7
uniprot id: A0A6I9L8Q7
uniprot id: A0A6I9LG15
names: Function
names: Similarity
messages: Belongs to the alpha-carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

230844:LOC102908306
gene id: 230844:LOC102908306
uniprot id: A0A6I9L083
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Serpina5
gene id: 230844:Serpina5
uniprot id: A0A6J0EC79
names: Similarity
messages: Belongs to the serpin family.

230844:Sepsecs
gene id: 230844:Sepsecs
uniprot id: A0A6I9L3W1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SepSecS family.
messages: Converts O-phosphoseryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis.
messages: Cytoplasm
messages: Homotetramer formed by a catalytic dimer and a non-catalytic dimer serving as a binding platform that orients tRNASec for catalysis. Each tetramer binds the CCA ends of two tRNAs which point to the active sites of the catalytic dimer.

230844:Aqp6
gene id: 230844:Aqp6
uniprot id: A0A6I9L0H5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

230844:LOC102909383
gene id: 230844:LOC102909383
uniprot id: A0A6J0DAY8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

230844:Tas1r3
gene id: 230844:Tas1r3
uniprot id: A0A6I9M8S0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

230844:Tent5a
gene id: 230844:Tent5a
uniprot id: A0A6I9LRH8
uniprot id: A0A6I9LX26
names: Similarity
messages: Belongs to the TENT family.

230844:LOC102925980
gene id: 230844:LOC102925980
uniprot id: A0A6I9MMM8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Pde5a
gene id: 230844:Pde5a
uniprot id: A0A6I9M9C0
uniprot id: A0A6J0EB61
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

230844:LOC102911454
gene id: 230844:LOC102911454
uniprot id: A0A6I9MD82
names: Similarity
messages: Belongs to the folate receptor family.

230844:LOC102915402
gene id: 230844:LOC102915402
uniprot id: A0A6I9LXT9
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

230844:Pop5
gene id: 230844:Pop5
uniprot id: A0A6I9M441
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic/archaeal RNase P protein component 2 family.
messages: Component of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends.
messages: nucleolus

230844:LOC102914942
gene id: 230844:LOC102914942
uniprot id: A0A6I9MIV0
names: Similarity
messages: Belongs to the cytochrome P450 family.

230844:Cenpi
gene id: 230844:Cenpi
uniprot id: A0A6I9LXH5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CENP-I/CTF3 family.
messages: Nucleus
messages: centromere

230844:Gstm3
gene id: 230844:Gstm3
uniprot id: A0A6I9LAR4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GST superfamily. Mu family.
messages: Cytoplasm

230844:Tbcb
gene id: 230844:Tbcb
uniprot id: A0A6I9LTU6
names: Similarity
messages: Belongs to the TBCB family.

230844:Drd2
gene id: 230844:Drd2
uniprot id: A0A6I9KWR1
uniprot id: A0A6I9L3I1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Golgi apparatus membrane
messages: Membrane

230844:Med12l
gene id: 230844:Med12l
uniprot id: A0A6J0CM48
uniprot id: A0A6J0CPS3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Mediator complex subunit 12 family.
messages: Nucleus

230844:Snrpe
gene id: 230844:Snrpe
uniprot id: A0A6I9MAH9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the snRNP Sm proteins family.
messages: Nucleus
messages: Plays a role in pre-mRNA splicing as a core component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. As a component of the minor spliceosome, involved in the splicing of U12-type introns in pre-mRNAs. As part of the U7 snRNP it is involved in histone 3'-end processing.
messages: cytosol

230844:Eef1akmt1
gene id: 230844:Eef1akmt1
uniprot id: A0A6I9LQR9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. EFM5 family.
messages: Cytoplasm
messages: Protein-lysine methyltransferase that selectively catalyzes the trimethylation of EEF1A at 'Lys-79'.
messages: Was originally thought to be an N(6)-adenine-specific DNA methyltransferase based on primary sequence and predicted secondary structure.

230844:LOC102921074
gene id: 230844:LOC102921074
uniprot id: A0A6I9M718
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

230844:LOC102925803
gene id: 230844:LOC102925803
uniprot id: A0A6I9LR60
names: Similarity
messages: Belongs to the alpha-carbonic anhydrase family.

230844:Ctso
gene id: 230844:Ctso
uniprot id: A0A6I9LVE6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C1 family.
messages: Lysosome

230844:LOC102915811
gene id: 230844:LOC102915811
uniprot id: A0A6I9M5Q5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Clstn2
gene id: 230844:Clstn2
uniprot id: A0A6I9L9B2
uniprot id: A0A6J0D322
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calsyntenin family.
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Postsynaptic cell membrane

230844:Sptssa
gene id: 230844:Sptssa
uniprot id: A0A6I9L1N5
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

230844:LOC102912194
gene id: 230844:LOC102912194
uniprot id: A0A6I9L7E5
names: Similarity
messages: Belongs to the histone H3 family.

230844:Psmb2
gene id: 230844:Psmb2
uniprot id: A0A6I9MK34
uniprot id: A0A6I9MM01
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1B family.
messages: Component of the proteasome complex.
messages: Component of the proteasome, a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.
messages: Cytoplasm
messages: Nucleus

230844:Col18a1
gene id: 230844:Col18a1
uniprot id: A0A6J0CPL6
uniprot id: A0A6J0CPL9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

230844:Rab3c
gene id: 230844:Rab3c
uniprot id: A0A6I9LMC8
uniprot id: A0A6J0DS95
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Cell membrane
messages: Protein transport. Probably involved in vesicular traffic.

230844:Corin
gene id: 230844:Corin
uniprot id: A0A6I9LI93
names: Caution
names: Subcellular Location Annotation
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

230844:Mrpl37
gene id: 230844:Mrpl37
uniprot id: A0A6I9L5W9
names: Subcellular Location Annotation
messages: Mitochondrion

230844:LOC102909347
gene id: 230844:LOC102909347
uniprot id: A0A6I9MDE1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

230844:Tmed3
gene id: 230844:Tmed3
uniprot id: A0A6J0EC15
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EMP24/GP25L family.
messages: Endoplasmic reticulum membrane
messages: Endoplasmic reticulum-Golgi intermediate compartment membrane
messages: Membrane
messages: cis-Golgi network membrane

230844:Csrnp2
gene id: 230844:Csrnp2
uniprot id: A0A6J0DLJ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AXUD1 family.
messages: Nucleus

230844:Ppp6r3
gene id: 230844:Ppp6r3
uniprot id: A0A6I9LK34
uniprot id: A0A6I9LKZ8
uniprot id: A0A6I9LQ22
uniprot id: A0A6J0DFF4
uniprot id: A0A6J0DHN2
uniprot id: A0A6J0DND5
uniprot id: A0A6J0DNE2
names: Similarity
messages: Belongs to the SAPS family.

230844:Gys1
gene id: 230844:Gys1
uniprot id: A0A6I9LPP5
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 3 family.
messages: Transfers the glycosyl residue from UDP-Glc to the non-reducing end of alpha-1,4-glucan.

230844:Hoxa13
gene id: 230844:Hoxa13
uniprot id: A0A6I9LU93
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Abd-B homeobox family.
messages: Nucleus

230844:LOC102912804
gene id: 230844:LOC102912804
uniprot id: A0A6I9M2V1
names: Similarity
messages: Belongs to the neutral sphingomyelinase family.

230844:LOC102902959
gene id: 230844:LOC102902959
uniprot id: A0A6I9L3U3
names: Similarity
messages: Belongs to the spermidine/spermine synthase family.

230844:Alx3
gene id: 230844:Alx3
uniprot id: A0A6I9LAT5
names: Subcellular Location Annotation
messages: Nucleus

230844:Spaca3
gene id: 230844:Spaca3
uniprot id: A0A6I9M9W0
names: Similarity
messages: Belongs to the glycosyl hydrolase 22 family.

230844:Sgcg
gene id: 230844:Sgcg
uniprot id: A0A6I9M2C2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sarcoglycan beta/delta/gamma/zeta family.
messages: cytoskeleton
messages: sarcolemma

230844:Mab21l2
gene id: 230844:Mab21l2
uniprot id: A0A6I9L3M8
names: Similarity
messages: Belongs to the mab-21 family.

230844:Rhot2
gene id: 230844:Rhot2
uniprot id: A0A6I9LGL1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial Rho GTPase family.
messages: Membrane
messages: Mitochondrial GTPase involved in mitochondrial trafficking.
messages: Mitochondrion outer membrane

230844:Pip4p2
gene id: 230844:Pip4p2
uniprot id: A0A6I9LQM2
names: Function
names: Subcellular Location Annotation
messages: Catalyzes the hydrolysis of phosphatidylinositol-4,5-bisphosphate (PtdIns-4,5-P2) to phosphatidylinositol-4-phosphate (PtdIns-4-P).
messages: Endosome membrane
messages: Late endosome membrane
messages: Lysosome membrane
messages: Membrane
messages: phagosome membrane

230844:Gng11
gene id: 230844:Gng11
uniprot id: A0A6I9M6J9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G protein gamma family.
messages: Cell membrane
messages: G proteins are composed of 3 units; alpha, beta and gamma.
messages: Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.
messages: Membrane

230844:LOC102910651
gene id: 230844:LOC102910651
uniprot id: A0A6I9MHN4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor T2R family.
messages: Membrane

230844:Arhgef7
gene id: 230844:Arhgef7
uniprot id: A0A6I9LCP2
uniprot id: A0A6I9LS14
uniprot id: A0A6J0DK04
names: Subcellular Location Annotation
messages: lamellipodium

230844:Csk
gene id: 230844:Csk
uniprot id: A0A6I9L1S5
names: Similarity
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.

230844:Gsk3a
gene id: 230844:Gsk3a
uniprot id: A0A6I9LQ50
names: Similarity
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. GSK-3 subfamily.

230844:Alx4
gene id: 230844:Alx4
uniprot id: A0A6I9MIV8
names: Subcellular Location Annotation
messages: Nucleus

230844:Soga3
gene id: 230844:Soga3
uniprot id: A0A6I9M8A3
names: Similarity
messages: Belongs to the SOGA family.

230844:Atp2c2
gene id: 230844:Atp2c2
uniprot id: A0A6J0ECH0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIA subfamily.
messages: Catalyzes the hydrolysis of ATP coupled with the transport of calcium.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

230844:Plxnc1
gene id: 230844:Plxnc1
uniprot id: A0A6I9MB83
names: Caution
names: Similarity
messages: Belongs to the plexin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

230844:LOC102920059
gene id: 230844:LOC102920059
uniprot id: A0A6I9LY58
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

230844:Ovol1
gene id: 230844:Ovol1
uniprot id: A0A6I9LQD2
names: Subcellular Location Annotation
messages: Nucleus

230844:LOC102903317
gene id: 230844:LOC102903317
uniprot id: A0A6I9LGG4
uniprot id: A0A6J0DNM2
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

230844:Plpp2
gene id: 230844:Plpp2
uniprot id: A0A6I9LG03
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PA-phosphatase related phosphoesterase family.
messages: Membrane

230844:Arhgef11
gene id: 230844:Arhgef11
uniprot id: A0A6J0D784
uniprot id: A0A6J0DBR0
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Membrane

230844:Ada
gene id: 230844:Ada
uniprot id: A0A6I9KTY5
uniprot id: A0A6I9L0L5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.
messages: Cell junction
messages: Cell membrane
messages: Cytoplasmic vesicle lumen

230844:Ugt8
gene id: 230844:Ugt8
uniprot id: A0A6I9KSQ3
names: Similarity
messages: Belongs to the UDP-glycosyltransferase family.

230844:Ca4
gene id: 230844:Ca4
uniprot id: A0A6I9LQF2
names: Function
names: Similarity
messages: Belongs to the alpha-carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

230844:Col4a5
gene id: 230844:Col4a5
uniprot id: A0A6I9KYT1
uniprot id: A0A6J0CXI6
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Type IV collagen is the major structural component of glomerular basement membranes (GBM), forming a 'chicken-wire' meshwork together with laminins, proteoglycans and entactin/nidogen.
messages: basement membrane

230844:Mms19
gene id: 230844:Mms19
uniprot id: A0A6I9LZG2
uniprot id: A0A6J0E7B0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MET18/MMS19 family.
messages: Component of the CIA complex.
messages: Key component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into apoproteins specifically involved in DNA metabolism and genomic integrity. In the CIA complex, MMS19 acts as an adapter between early-acting CIA components and a subset of cellular target iron-sulfur proteins.
messages: Nucleus
messages: spindle

230844:Gclc
gene id: 230844:Gclc
uniprot id: A0A6I9L652
names: Similarity
messages: Belongs to the glutamate--cysteine ligase type 3 family.

230844:Rbm22
gene id: 230844:Rbm22
uniprot id: A0A6I9LZL5
names: Similarity
messages: Belongs to the SLT11 family.

230844:LOC102909467
gene id: 230844:LOC102909467
uniprot id: A0A6I9MJU6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Ncbp3
gene id: 230844:Ncbp3
uniprot id: A0A6I9M8I6
names: Similarity
messages: Belongs to the NCBP3 family.

230844:Aldh3a2
gene id: 230844:Aldh3a2
uniprot id: A0A6I9KYQ9
uniprot id: A0A6J0CZW1
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

230844:Pign
gene id: 230844:Pign
uniprot id: A0A6I9MGV5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PIGG/PIGN/PIGO family. PIGN subfamily.
messages: Endoplasmic reticulum membrane
messages: Ethanolamine phosphate transferase involved in glycosylphosphatidylinositol-anchor biosynthesis. Transfers ethanolamine phosphate to the first alpha-1,4-linked mannose of the glycosylphosphatidylinositol precursor of GPI-anchor.
messages: Membrane

230844:LOC102919794
gene id: 230844:LOC102919794
uniprot id: A0A6I9MR01
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Apobec1
gene id: 230844:Apobec1
uniprot id: A0A6J0CL02
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: Nucleus

230844:Icam2
gene id: 230844:Icam2
uniprot id: A0A6I9KZ97
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the immunoglobulin superfamily. ICAM family.
messages: Membrane

230844:LOC102914286
gene id: 230844:LOC102914286
uniprot id: A0A6I9M036
names: Subcellular Location Annotation
messages: Nucleus

230844:LOC102915326
gene id: 230844:LOC102915326
uniprot id: A0A6I9MDA3
names: Similarity
messages: Belongs to the 'GDXG' lipolytic enzyme family.

230844:LOC102904164
gene id: 230844:LOC102904164
uniprot id: A0A6I9M3M8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Sbf1
gene id: 230844:Sbf1
uniprot id: A0A6I9L370
uniprot id: A0A6J0D613
uniprot id: A0A6J0DB25
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily.

230844:Lyplal1
gene id: 230844:Lyplal1
uniprot id: A0A6I9KVX3
names: Similarity
messages: Belongs to the AB hydrolase superfamily. AB hydrolase 2 family.

230844:Fscn2
gene id: 230844:Fscn2
uniprot id: A0A6I9LZV0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fascin family.
messages: cytoskeleton

230844:Mmp12
gene id: 230844:Mmp12
uniprot id: A0A6I9LRK1
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M10A family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Can bind about 5 Ca(2+) ions per subunit.

230844:Dok4
gene id: 230844:Dok4
uniprot id: A0A6J0E1Q5
names: Similarity
messages: Belongs to the DOK family. Type B subfamily.

230844:Htr1a
gene id: 230844:Htr1a
uniprot id: A0A6J0DVA7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: G-protein coupled receptor for 5-hydroxytryptamine (serotonin). Also functions as a receptor for various drugs and psychoactive substances. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Beta-arrestin family members inhibit signaling via G proteins and mediate activation of alternative signaling pathways. Signaling inhibits adenylate cyclase activity and activates a phosphatidylinositol-calcium second messenger system that regulates the release of Ca(2+) ions from intracellular stores. Plays a role in the regulation of 5-hydroxytryptamine release and in the regulation of dopamine and 5-hydroxytryptamine metabolism. Plays a role in the regulation of dopamine and 5-hydroxytryptamine levels in the brain, and thereby affects neural activity, mood and behavior. Plays a role in the response to anxiogenic stimuli.
messages: Membrane
messages: dendrite

230844:Arl5b
gene id: 230844:Arl5b
uniprot id: A0A6I9M422
names: Similarity
messages: Belongs to the small GTPase superfamily. Arf family.

230844:Defb116
gene id: 230844:Defb116
uniprot id: A0A6J0DXP7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the beta-defensin family.
messages: Has antibacterial activity.
messages: Secreted

230844:Tmpo
gene id: 230844:Tmpo
uniprot id: A0A6I9L9T5
uniprot id: A0A6I9LBC5
uniprot id: A0A6I9LII1
uniprot id: A0A6I9LJP0
uniprot id: A0A6I9LNH2
names: Similarity
messages: Belongs to the LEM family.

230844:Phc3
gene id: 230844:Phc3
uniprot id: A0A6I9KUN4
uniprot id: A0A6I9L3U1
uniprot id: A0A6J0DME0
uniprot id: A0A6J0DMF2
uniprot id: A0A6J0DTP5
names: Subcellular Location Annotation
messages: Nucleus

230844:Ier2
gene id: 230844:Ier2
uniprot id: A0A6I9MLI2
names: Similarity
messages: Belongs to the IER family.

230844:Ipo5
gene id: 230844:Ipo5
uniprot id: A0A6I9LGH0
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

230844:Pla2g4a
gene id: 230844:Pla2g4a
uniprot id: A0A6I9LA28
names: Domain
messages: The N-terminal C2 domain associates with lipid membranes upon calcium binding.

230844:Castor1
gene id: 230844:Castor1
uniprot id: A0A6I9L4F6
uniprot id: A0A6J0CWA7
names: Similarity
messages: Belongs to the GATS family.

230844:Fbxo48
gene id: 230844:Fbxo48
uniprot id: A0A6I9MDW7
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Part of the SCF (SKP1-CUL1-F-box) E3 ubiquitin-protein ligase complex SCF(FBXO9) composed of CUL1, SKP1, RBX1 and FBXO9. Interacts with TTI1 and TELO2; when TTI1 and TELO2 are phosphorylated by CK2.
messages: Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins and plays a role in several biological processes such as cell cycle, cell proliferation, or maintenance of chromosome stability. Ubiquitinates mTORC1-bound TTI1 and TELO2 when they are phosphorylated by CK2 following growth factor deprivation, leading to their degradation. In contrast, does not mediate ubiquitination of TTI1 and TELO2 when they are part of the mTORC2 complex. As a consequence, mTORC1 is inactivated to restrain cell growth and protein translation, while mTORC2 is the activated due to the relief of feedback inhibition by mTORC1. Plays a role in maintaining epithelial cell survival by regulating the turn-over of chromatin modulator PRMT4 through ubiquitination and degradation by the proteasomal pathway. Regulates also PPARgamma stability by facilitating PPARgamma/PPARG ubiquitination and thereby plays a role in adipocyte differentiation.

230844:LOC102906784
gene id: 230844:LOC102906784
uniprot id: A0A6J0CND5
uniprot id: A0A6J0CPX0
uniprot id: A0A6J0CQP3
names: Subcellular Location Annotation
messages: Nucleus

230844:Etfb
gene id: 230844:Etfb
uniprot id: A0A6I9LX00
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ETF beta-subunit/FixA family.
messages: Heterodimer of an alpha and a beta subunit.
messages: Mitochondrion matrix
messages: The electron transfer flavoprotein serves as a specific electron acceptor for several dehydrogenases, including five acyl-CoA dehydrogenases, glutaryl-CoA and sarcosine dehydrogenase. It transfers the electrons to the main mitochondrial respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase).

230844:Mrpl22
gene id: 230844:Mrpl22
uniprot id: A0A6I9LZ49
names: Similarity
messages: Belongs to the universal ribosomal protein uL22 family.

230844:LOC102914137
gene id: 230844:LOC102914137
uniprot id: A0A6I9LF63
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Gpi
gene id: 230844:Gpi
uniprot id: A0A6I9LLX2
names: Similarity
messages: Belongs to the GPI family.

230844:Hoxa7
gene id: 230844:Hoxa7
uniprot id: A0A6J0DTY6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Antp homeobox family.
messages: Nucleus

230844:Hdc
gene id: 230844:Hdc
uniprot id: A0A6I9LXK6
names: Similarity
names: Subunit
messages: Belongs to the group II decarboxylase family.
messages: Homodimer.

230844:Kcnab2
gene id: 230844:Kcnab2
uniprot id: A0A6J0DSZ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the shaker potassium channel beta subunit family.
messages: Cell membrane
messages: Membrane
messages: axon
messages: cytoskeleton
messages: synaptosome

230844:LOC102925039
gene id: 230844:LOC102925039
uniprot id: A0A6I9MKS6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome P450 family.
messages: Membrane
messages: Microsome membrane

230844:Ppargc1b
gene id: 230844:Ppargc1b
uniprot id: A0A6I9LM78
uniprot id: A0A6I9LUI0
uniprot id: A0A6J0DUP2
uniprot id: A0A6J0E1J9
names: Subcellular Location Annotation
messages: Nucleus

230844:Dazap2
gene id: 230844:Dazap2
uniprot id: A0A6I9LP29
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus speckle
messages: nuclear body

230844:Oat
gene id: 230844:Oat
uniprot id: A0A6I9L5L6
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

230844:Npc2
gene id: 230844:Npc2
uniprot id: A0A6I9LPP9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NPC2 family.
messages: Secreted

230844:Etfrf1
gene id: 230844:Etfrf1
uniprot id: A0A6I9M498
names: Similarity
messages: Belongs to the complex I LYR family.

230844:Micos10
gene id: 230844:Micos10
uniprot id: A0A6I9LLT6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MICOS complex subunit Mic10 family.
messages: Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane.
messages: Component of the mitochondrial contact site and cristae organizing system (MICOS) complex.
messages: Mitochondrion inner membrane

230844:Tm2d2
gene id: 230844:Tm2d2
uniprot id: A0A6I9LPW7
names: Subcellular Location Annotation
messages: Membrane

230844:Wrn
gene id: 230844:Wrn
uniprot id: A0A6J0D0U9
uniprot id: A0A6J0D3Y9
names: Similarity
messages: Belongs to the helicase family. RecQ subfamily.

230844:Gga3
gene id: 230844:Gga3
uniprot id: A0A6I9MBA2
uniprot id: A0A6J0CLR3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GGA protein family.
messages: Early endosome membrane
messages: Endosome membrane
messages: Membrane
messages: trans-Golgi network membrane

230844:Hhipl1
gene id: 230844:Hhipl1
uniprot id: A0A6I9KV79
names: Caution
names: Similarity
messages: Belongs to the HHIP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

230844:Rxfp3
gene id: 230844:Rxfp3
uniprot id: A0A6I9M6B9
names: Subcellular Location Annotation
messages: Membrane

230844:Celf6
gene id: 230844:Celf6
uniprot id: A0A6I9KUT1
uniprot id: A0A6I9L1C1
uniprot id: A0A6J0DWH7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CELF/BRUNOL family.
messages: Nucleus

230844:Ppp1r1a
gene id: 230844:Ppp1r1a
uniprot id: A0A6I9LNU1
names: Similarity
messages: Belongs to the protein phosphatase inhibitor 1 family.

230844:Cct6b
gene id: 230844:Cct6b
uniprot id: A0A6I9LTH1
uniprot id: A0A6J0E9W3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TCP-1 chaperonin family.
messages: Cytoplasm

230844:Fam214a
gene id: 230844:Fam214a
uniprot id: A0A6I9KZ86
uniprot id: A0A6I9L6F5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATOS family.
messages: Nucleus

230844:Lyg2
gene id: 230844:Lyg2
uniprot id: A0A6J0DF70
names: Similarity
messages: Belongs to the glycosyl hydrolase 23 family.

230844:LOC102916471
gene id: 230844:LOC102916471
uniprot id: A0A6I9LAC0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

230844:LOC102903480
gene id: 230844:LOC102903480
uniprot id: A0A6I9MH14
names: Similarity
messages: Belongs to the NipSnap family.

230844:LOC102924931
gene id: 230844:LOC102924931
uniprot id: A0A6I9MCT1
uniprot id: A0A6J0CUW3
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Interacts with UHRF2/NIRF.
messages: May be involved in cell cycle regulation.
messages: Nucleus

230844:Uvssa
gene id: 230844:Uvssa
uniprot id: A0A6I9L4N1
names: Similarity
messages: Belongs to the UVSSA family.

230844:LOC102917557
gene id: 230844:LOC102917557
uniprot id: A0A6I9LMX6
uniprot id: A0A6J0DMC7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bZIP family. PAR subfamily.
messages: Nucleus

230844:Ago2
gene id: 230844:Ago2
uniprot id: A0A6I9M856
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argonaute family. Ago subfamily.
messages: Hydroxylated. 4-hydroxylation appears to enhance protein stability but is not required for miRNA-binding or endonuclease activity.
messages: Interacts with DICER1 through its Piwi domain and with TARBP2 during assembly of the RNA-induced silencing complex (RISC). Together, DICER1, AGO2 and TARBP2 constitute the trimeric RISC loading complex (RLC), or micro-RNA (miRNA) loading complex (miRLC). Within the RLC/miRLC, DICER1 and TARBP2 are required to process precursor miRNAs (pre-miRNAs) to mature miRNAs and then load them onto AGO2. AGO2 bound to the mature miRNA constitutes the minimal RISC and may subsequently dissociate from DICER1 and TARBP2. Note however that the term RISC has also been used to describe the trimeric RLC/miRLC. The formation of RISC complexes containing siRNAs rather than miRNAs appears to occur independently of DICER1. Interacts with AGO1. Also interacts with DDB1, DDX5, DDX6, DDX20, DHX30, DHX36, DDX47, DHX9, ELAVL, FXR1, GEMIN4, HNRNPF, IGF2BP1, ILF3, IMP8, MATR3, PABPC1, PRMT5, P4HA1, P4HB, RBM4, SART3, TNRC6A, TNRC6B, UPF1 and YBX1. Interacts with the P-body components DCP1A and XRN1. Associates with polysomes and messenger ribonucleoproteins (mNRPs). Interacts with RBM4; the interaction is modulated under stress-induced conditions, occurs under both cell proliferation and differentiation conditions and in an RNA-and phosphorylation-independent manner. Interacts with LIMD1, WTIP and AJUBA. Interacts with TRIM71. Interacts with APOBEC3G in an RNA-dependent manner. Interacts with APOBEC3A, APOBEC3C, APOBEC3F and APOBEC3H. Interacts with DICER1, TARBP2, EIF6, MOV10 and RPL7A (60S ribosome subunit); they form a large RNA-induced silencing complex (RISC). Interacts with FMR1. Interacts with ZFP36.
messages: Nucleus
messages: P-body
messages: Required for RNA-mediated gene silencing (RNAi) by the RNA-induced silencing complex (RISC). The 'minimal RISC' appears to include AGO2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the mRNA specifically by AGO2. Binding of RISC to a partially complementary mRNA results in silencing through inhibition of translation, and this is independent of endonuclease activity. May inhibit translation initiation by binding to the 7-methylguanosine cap, thereby preventing the recruitment of the translation initiation factor eIF4-E. May also inhibit translation initiation via interaction with EIF6, which itself binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit. The inhibition of translational initiation leads to the accumulation of the affected mRNA in cytoplasmic processing bodies (P-bodies), where mRNA degradation may subsequently occur. In some cases RISC-mediated translational repression is also observed for miRNAs that perfectly match the 3' untranslated region (3'-UTR). Can also up-regulate the translation of specific mRNAs under certain growth conditions. Binds to the AU element of the 3'-UTR of the TNF (TNF-alpha) mRNA and up-regulates translation under conditions of serum starvation. Also required for transcriptional gene silencing (TGS), in which short RNAs known as antigene RNAs or agRNAs direct the transcriptional repression of complementary promoter regions.
messages: The Piwi domain may perform RNA cleavage by a mechanism similar to that of RNase H. However, while RNase H utilizes a triad of Asp-Asp-Glu (DDE) for metal ion coordination, this protein appears to utilize a triad of Asp-Asp-His (DDH).

230844:Acsl1
gene id: 230844:Acsl1
uniprot id: A0A6I9KU87
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP-dependent AMP-binding enzyme family.
messages: Catalyzes the conversion of long-chain fatty acids to their active form acyl-CoAs for both synthesis of cellular lipids, and degradation via beta-oxidation.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Mitochondrion outer membrane

230844:Uts2
gene id: 230844:Uts2
uniprot id: A0A6I9L1I8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the urotensin-2 family.
messages: Secreted

230844:Mmaa
gene id: 230844:Mmaa
uniprot id: A0A6J0E258
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ArgK/MeaB subfamily.

230844:Mcm4
gene id: 230844:Mcm4
uniprot id: A0A6J0CWE0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as component of the MCM2-7 complex (MCM complex) which is the replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity.
messages: Belongs to the MCM family.
messages: Chromosome
messages: Component of the MCM2-7 complex.
messages: Nucleus

230844:Elovl3
gene id: 230844:Elovl3
uniprot id: A0A6I9LQC6
names: Caution
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELO family. ELOVL3 subfamily.
messages: Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme with higher activity toward C18 acyl-CoAs, especially C18:0 acyl-CoAs. May participate to the production of saturated and monounsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: N-Glycosylated.
messages: The C-terminal di-lysine motif may confer endoplasmic reticulum localization.

230844:Rflna
gene id: 230844:Rflna
uniprot id: A0A6I9KTI6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Refilin family.
messages: Interacts with FLNA and FLNB.
messages: cytoskeleton

230844:Tmem225
gene id: 230844:Tmem225
uniprot id: A0A6I9LML1
names: Subcellular Location Annotation
messages: Membrane

230844:Capn6
gene id: 230844:Capn6
uniprot id: A0A6I9KSG6
names: Caution
names: Similarity
messages: Belongs to the peptidase C2 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

230844:Crabp2
gene id: 230844:Crabp2
uniprot id: A0A6I9L4H1
names: Similarity
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.

230844:Fancm
gene id: 230844:Fancm
uniprot id: A0A6J0E698
names: Similarity
messages: Belongs to the DEAD box helicase family. DEAH subfamily. FANCM sub-subfamily.

230844:Gpr34
gene id: 230844:Gpr34
uniprot id: A0A6J0D851
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Orphan receptor.

230844:Serpine2
gene id: 230844:Serpine2
uniprot id: A0A6I9L2Z7
names: Similarity
messages: Belongs to the serpin family.

230844:Cdk16
gene id: 230844:Cdk16
uniprot id: A0A6I9M886
names: Similarity
messages: Belongs to the protein kinase superfamily.

230844:Tbrg1
gene id: 230844:Tbrg1
uniprot id: A0A6I9MMM7
names: Subcellular Location Annotation
messages: Nucleus

230844:Upp2
gene id: 230844:Upp2
uniprot id: A0A6I9LYN1
names: Function
names: Similarity
messages: Belongs to the PNP/UDP phosphorylase family.
messages: Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis.

230844:Chmp4c
gene id: 230844:Chmp4c
uniprot id: A0A6I9L7I1
names: Similarity
messages: Belongs to the SNF7 family.

230844:Adra1b
gene id: 230844:Adra1b
uniprot id: A0A6J0E502
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Cytoplasm
messages: Membrane
messages: Nucleus membrane
messages: This alpha-adrenergic receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. Its effect is mediated by G(q) and G(11) proteins. Nuclear ADRA1A-ADRA1B heterooligomers regulate phenylephrine (PE)-stimulated ERK signaling in cardiac myocytes.
messages: caveola

230844:Cxcr3
gene id: 230844:Cxcr3
uniprot id: A0A6I9LE13
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Homomer. Forms heteromers with ACKR4.
messages: Membrane

230844:Cenpu
gene id: 230844:Cenpu
uniprot id: A0A6I9L054
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CENP-U/AME1 family.
messages: Nucleus

230844:Ap1g1
gene id: 230844:Ap1g1
uniprot id: A0A6I9L715
uniprot id: A0A6J0CYX4
names: Similarity
messages: Belongs to the adaptor complexes large subunit family.

230844:Kcng2
gene id: 230844:Kcng2
uniprot id: A0A6I9KZH0
names: Subcellular Location Annotation
messages: Membrane

230844:Elof1
gene id: 230844:Elof1
uniprot id: A0A6I9LGD1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELOF1 family.
messages: Nucleus
messages: Transcription elongation factor implicated in the maintenance of proper chromatin structure in actively transcribed regions.

230844:Znf446
gene id: 230844:Znf446
uniprot id: A0A6J0CU23
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the krueppel C2H2-type zinc-finger protein family.
messages: Nucleus

230844:Ticam1
gene id: 230844:Ticam1
uniprot id: A0A6I9LPQ7
names: Domain
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Homodimer. Found in a multi-helicase-TICAM1 complex at least composed of DHX36, DDX1, DDX21 and TICAM1.
messages: Involved in innate immunity against invading pathogens. Adapter used by TLR3, TLR4 (through TICAM2) and TLR5 to mediate NF-kappa-B and interferon-regulatory factor (IRF) activation, and to induce apoptosis. Ligand binding to these receptors results in TRIF recruitment through its TIR domain. Distinct protein-interaction motifs allow recruitment of the effector proteins TBK1, TRAF6 and RIPK1, which in turn, lead to the activation of transcription factors IRF3 and IRF7, NF-kappa-B and FADD respectively. Phosphorylation by TBK1 on the pLxIS motif leads to recruitment and subsequent activation of the transcription factor IRF3 to induce expression of type I interferon and exert a potent immunity against invading pathogens. Component of a multi-helicase-TICAM1 complex that acts as a cytoplasmic sensor of viral double-stranded RNA (dsRNA) and plays a role in the activation of a cascade of antiviral responses including the induction of pro-inflammatory cytokines.
messages: Mitochondrion
messages: The N-terminal region is essential for activation of the IFNB promoter activity.
messages: autophagosome
messages: cytosol

230844:Nae1
gene id: 230844:Nae1
uniprot id: A0A6I9LKB1
names: Function
names: Similarity
messages: Belongs to the ubiquitin-activating E1 family. ULA1 subfamily.
messages: Regulatory subunit of the dimeric UBA3-NAE1 E1 enzyme. E1 activates NEDD8 by first adenylating its C-terminal glycine residue with ATP, thereafter linking this residue to the side chain of the catalytic cysteine, yielding a NEDD8-UBA3 thioester and free AMP. E1 finally transfers NEDD8 to the catalytic cysteine of UBE2M.

230844:Gpr179
gene id: 230844:Gpr179
uniprot id: A0A6I9L608
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 3 family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

230844:Ppif
gene id: 230844:Ppif
uniprot id: A0A6I9M258
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

230844:Taf9b
gene id: 230844:Taf9b
uniprot id: A0A6J0CGV1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAF9 family.
messages: Nucleus

230844:Inhbe
gene id: 230844:Inhbe
uniprot id: A0A6I9KY53
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TGF-beta family.
messages: Homodimeric or heterodimeric through association with alpha and beta subunits, linked by one or more disulfide bonds. Inhibins are heterodimers of one alpha and one beta subunit. Activins are homo- or heterodimers of beta subunits only.
messages: Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition. Inhibins appear to oppose the functions of activins.
messages: Secreted

230844:Rc3h1
gene id: 230844:Rc3h1
uniprot id: A0A6I9LMX9
uniprot id: A0A6J0DKY5
names: Subcellular Location Annotation
messages: P-body

230844:Fga
gene id: 230844:Fga
uniprot id: A0A6I9LMI2
names: Subcellular Location Annotation
names: Subunit
messages: Heterohexamer; disulfide linked. Contains 2 sets of 3 non-identical chains (alpha, beta and gamma). The 2 heterotrimers are in head to head conformation with the N-termini in a small central domain.
messages: Secreted

230844:Adgre1
gene id: 230844:Adgre1
uniprot id: A0A6J0CTN2
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 2 family. Adhesion G-protein coupled receptor (ADGR) subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

230844:LOC102906927
gene id: 230844:LOC102906927
uniprot id: A0A6I9LEH5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PIGP family.
messages: Membrane
messages: Part of the complex catalyzing the transfer of N-acetylglucosamine from UDP-N-acetylglucosamine to phosphatidylinositol, the first step of GPI biosynthesis.

230844:Tnfrsf14
gene id: 230844:Tnfrsf14
uniprot id: A0A6I9LXV6
uniprot id: A0A6J0CFT5
uniprot id: A0A6J0CI88
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

230844:B9d2
gene id: 230844:B9d2
uniprot id: A0A6I9LTS3
names: Subcellular Location Annotation
messages: cilium basal body

230844:Tpm3
gene id: 230844:Tpm3
uniprot id: A0A6I9L3E1
uniprot id: A0A6I9L3E6
uniprot id: A0A6I9LBL0
uniprot id: A0A6I9LBL4
uniprot id: A0A6I9LBL5
uniprot id: A0A6I9LBL9
uniprot id: A0A6I9LFE5
uniprot id: A0A6I9LFF2
uniprot id: A0A6I9LFF8
uniprot id: A0A6J0D547
uniprot id: A0A6J0D552
uniprot id: A0A6J0D696
uniprot id: A0A6J0D6U4
uniprot id: A0A6J0D7C4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tropomyosin family.
messages: cytoskeleton

230844:Tgif2lx
gene id: 230844:Tgif2lx
uniprot id: A0A6I9M6G4
names: Subcellular Location Annotation
messages: Nucleus

230844:Ctnna1
gene id: 230844:Ctnna1
uniprot id: A0A6J0DFQ1
names: Similarity
messages: Belongs to the vinculin/alpha-catenin family.

230844:Nop58
gene id: 230844:Nop58
uniprot id: A0A6I9LCQ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NOP5/NOP56 family.
messages: nucleolus
messages: nucleoplasm

230844:Pex2
gene id: 230844:Pex2
uniprot id: A0A6I9LJ13
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pex2/pex10/pex12 family.
messages: Membrane
messages: Peroxisome membrane

230844:LOC102918358
gene id: 230844:LOC102918358
uniprot id: A0A6I9M6R5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Tcta
gene id: 230844:Tcta
uniprot id: A0A6I9L713
uniprot id: A0A6J0DA62
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TCTA family.
messages: May be required for cellular fusion during osteoclastogenesis.
messages: Membrane

230844:Zdhhc16
gene id: 230844:Zdhhc16
uniprot id: A0A6I9M6F2
uniprot id: A0A6I9MAL8
uniprot id: A0A6J0EB28
uniprot id: A0A6J0EDB3
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

230844:Pgls
gene id: 230844:Pgls
uniprot id: A0A6J0EBG4
names: Function
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.
messages: Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.

230844:Ttc26
gene id: 230844:Ttc26
uniprot id: A0A6I9MAK3
names: Similarity
messages: Belongs to the IFT56 family.

230844:Polr1f
gene id: 230844:Polr1f
uniprot id: A0A6I9M8T7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic RPA43 RNA polymerase subunit family.
messages: DNA-dependent RNA polymerase which catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: nucleolus

230844:Snx31
gene id: 230844:Snx31
uniprot id: A0A6J0DPY1
names: Similarity
messages: Belongs to the sorting nexin family.

230844:LOC102915706
gene id: 230844:LOC102915706
uniprot id: A0A6I9M0J2
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fatty acid desaturase type 1 family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: The histidine box domains are involved in binding the catalytic metal ions.

230844:Bsx
gene id: 230844:Bsx
uniprot id: A0A6I9LML6
names: Subcellular Location Annotation
messages: Nucleus

230844:Mmp24
gene id: 230844:Mmp24
uniprot id: A0A6J0E1R7
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M10A family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Can bind about 5 Ca(2+) ions per subunit.

230844:Slc39a12
gene id: 230844:Slc39a12
uniprot id: A0A6J0E5T8
uniprot id: A0A6J0ED74
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZIP transporter (TC 2.A.5) family.
messages: Membrane

230844:Prkg2
gene id: 230844:Prkg2
uniprot id: A0A6I9L1U0
uniprot id: A0A6I9L9S3
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. cGMP subfamily.

230844:Cacna1b
gene id: 230844:Cacna1b
uniprot id: A0A6J0DQ59
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family.
messages: Membrane
messages: Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. This alpha-1B subunit gives rise to N-type calcium currents. N-type calcium channels belong to the 'high-voltage activated' (HVA) group. They are involved in pain signaling. Calcium channels containing alpha-1B subunit may play a role in directed migration of immature neurons.

230844:LOC102917423
gene id: 230844:LOC102917423
uniprot id: A0A6I9MFH3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Pik3cd
gene id: 230844:Pik3cd
uniprot id: A0A6J0D2A5
uniprot id: A0A6J0D2B0
uniprot id: A0A6J0D379
uniprot id: A0A6J0D4H7
uniprot id: A0A6J0D857
names: Similarity
messages: Belongs to the PI3/PI4-kinase family. Type III PI4K subfamily.

230844:LOC102922983
gene id: 230844:LOC102922983
uniprot id: A0A6I9MLC0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Gbf1
gene id: 230844:Gbf1
uniprot id: A0A6I9LQD1
uniprot id: A0A6I9LU56
uniprot id: A0A6I9LU61
uniprot id: A0A6I9M0N9
uniprot id: A0A6I9M2I0
uniprot id: A0A6I9M2I6
uniprot id: A0A6I9M6B8
uniprot id: A0A6J0E1Q0
uniprot id: A0A6J0E6R2
uniprot id: A0A6J0E9F3
names: Subcellular Location Annotation
messages: trans-Golgi network

230844:Rdh5
gene id: 230844:Rdh5
uniprot id: A0A6I9LS51
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

230844:Gnaz
gene id: 230844:Gnaz
uniprot id: A0A6I9LH44
uniprot id: A0A6J0DJE4
names: Similarity
messages: Belongs to the G-alpha family. G(i/o/t/z) subfamily.

230844:LOC102904021
gene id: 230844:LOC102904021
uniprot id: A0A6I9MP69
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calycin superfamily. Lipocalin family.
messages: Secreted

230844:LOC102908477
gene id: 230844:LOC102908477
uniprot id: A0A6I9LSM4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IAP family.
messages: Cytoplasm
messages: Nucleus

230844:Htr2c
gene id: 230844:Htr2c
uniprot id: A0A6I9LTB3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:LOC102928410
gene id: 230844:LOC102928410
uniprot id: A0A6I9L9Q2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Myo7b
gene id: 230844:Myo7b
uniprot id: A0A6J0D957
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
messages: cytoskeleton

230844:E2f2
gene id: 230844:E2f2
uniprot id: A0A6I9LBQ7
uniprot id: A0A6J0DIB7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the E2F/DP family.
messages: Nucleus

230844:S1pr2
gene id: 230844:S1pr2
uniprot id: A0A6I9M3S5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Septin4
gene id: 230844:Septin4
uniprot id: A0A6I9LGD0
uniprot id: A0A6I9LI38
uniprot id: A0A6I9LRK5
uniprot id: A0A6I9LRK9
uniprot id: A0A6I9LW42
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.
messages: Filament-forming cytoskeletal GTPase.
messages: Septins polymerize into heterooligomeric protein complexes that form filaments.

230844:Heatr1
gene id: 230844:Heatr1
uniprot id: A0A6J0DGV5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HEATR1/UTP10 family.
messages: Involved in nucleolar processing of pre-18S ribosomal RNA.
messages: nucleolus

230844:Stxbp3
gene id: 230844:Stxbp3
uniprot id: A0A6I9LMJ5
names: Similarity
messages: Belongs to the STXBP/unc-18/SEC1 family.

230844:LOC102911424
gene id: 230844:LOC102911424
uniprot id: A0A6I9LPS3
names: Function
names: Subunit
messages: In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins.
messages: Interacts with hair keratins.

230844:Kif23
gene id: 230844:Kif23
uniprot id: A0A6J0DSY5
uniprot id: A0A6J0DUB8
uniprot id: A0A6J0DUC7
uniprot id: A0A6J0DWL5
uniprot id: A0A6J0DWN2
uniprot id: A0A6J0DWN8
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

230844:LOC102911121
gene id: 230844:LOC102911121
uniprot id: A0A6I9M056
names: Function
names: Subunit
messages: In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins.
messages: Interacts with hair keratins.

230844:LOC102924211
gene id: 230844:LOC102924211
uniprot id: A0A6I9L322
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family.

230844:Mfng
gene id: 230844:Mfng
uniprot id: A0A6I9L9Y7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane

230844:Urad
gene id: 230844:Urad
uniprot id: A0A6I9LN03
names: Function
names: Similarity
messages: Belongs to the OHCU decarboxylase family.
messages: Catalyzes the stereoselective decarboxylation of 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU) to (S)-allantoin.

230844:Pkd1
gene id: 230844:Pkd1
uniprot id: A0A6I9L849
uniprot id: A0A6I9LL61
uniprot id: A0A6J0DBW2
uniprot id: A0A6J0DDJ6
uniprot id: A0A6J0DDP0
uniprot id: A0A6J0DE87
uniprot id: A0A6J0DIZ2
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polycystin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

230844:Nhsl2
gene id: 230844:Nhsl2
uniprot id: A0A6J0CPE1
uniprot id: A0A6J0CQR1
uniprot id: A0A6J0CRJ9
names: Similarity
messages: Belongs to the NHS family.

230844:Itfg1
gene id: 230844:Itfg1
uniprot id: A0A6J0E335
uniprot id: A0A6J0E922
names: Similarity
messages: Belongs to the TIP family.

230844:Lmf1
gene id: 230844:Lmf1
uniprot id: A0A6I9L9A3
uniprot id: A0A6J0DBL9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lipase maturation factor family.
messages: Endoplasmic reticulum membrane
messages: Involved in the maturation of specific proteins in the endoplasmic reticulum.
messages: Membrane

230844:LOC102926486
gene id: 230844:LOC102926486
uniprot id: A0A6J0CS33
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:LOC107400954
gene id: 230844:LOC107400954
uniprot id: A0A6J0D6M5
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c family.
messages: Binds 1 heme group per subunit.
messages: Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.
messages: Mitochondrion intermembrane space
messages: Plays a role in apoptosis. Suppression of the anti-apoptotic members or activation of the pro-apoptotic members of the Bcl-2 family leads to altered mitochondrial membrane permeability resulting in release of cytochrome c into the cytosol. Binding of cytochrome c to Apaf-1 triggers the activation of caspase-9, which then accelerates apoptosis by activating other caspases.

230844:Bco1
gene id: 230844:Bco1
uniprot id: A0A6I9LPV3
names: Cofactor
names: Similarity
messages: Belongs to the carotenoid oxygenase family.
messages: Binds 1 Fe(2+) ion per subunit.

230844:Aasdhppt
gene id: 230844:Aasdhppt
uniprot id: A0A6I9MJY8
names: Similarity
messages: Belongs to the P-Pant transferase superfamily. AcpS family.

230844:Gpr153
gene id: 230844:Gpr153
uniprot id: A0A6I9MEA5
uniprot id: A0A6J0CHQ1
uniprot id: A0A6J0CKB9
names: Subcellular Location Annotation
messages: Membrane

230844:Adora2a
gene id: 230844:Adora2a
uniprot id: A0A6I9L8F3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase.

230844:Map2k6
gene id: 230844:Map2k6
uniprot id: A0A6I9KTH2
names: Similarity
messages: Belongs to the protein kinase superfamily.

230844:Pparg
gene id: 230844:Pparg
uniprot id: A0A6I9LKD3
uniprot id: A0A6J0DAU4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the nuclear hormone receptor family. NR1 subfamily.
messages: Cytoplasm
messages: Heterodimer with other nuclear receptors.
messages: Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. May play a role in the regulation of circadian rhythm.
messages: Nucleus

230844:LOC102908040
gene id: 230844:LOC102908040
uniprot id: A0A6I9LQ69
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

230844:Slc16a9
gene id: 230844:Slc16a9
uniprot id: A0A6J0DC89
uniprot id: A0A6J0DE13
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family.
messages: Cell membrane
messages: Membrane

230844:Tmem123
gene id: 230844:Tmem123
uniprot id: A0A6I9LRL6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CD164 family.
messages: Membrane

230844:Pde3b
gene id: 230844:Pde3b
uniprot id: A0A6I9L907
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

230844:Trim47
gene id: 230844:Trim47
uniprot id: A0A6I9M080
names: Subcellular Location Annotation
messages: Cytoplasm

230844:Ndufaf4
gene id: 230844:Ndufaf4
uniprot id: A0A6I9LIE2
names: Similarity
names: Subunit
messages: Belongs to the NDUFAF4 family.
messages: Binds calmodulin. Interacts with NDUFAF3.

230844:Rtcb
gene id: 230844:Rtcb
uniprot id: A0A6I9LN29
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RtcB family.
messages: Binds 2 manganese ions per subunit.
messages: Catalytic component of the tRNA-splicing ligase complex.
messages: Catalytic subunit of the tRNA-splicing ligase complex that acts by directly joining spliced tRNA halves to mature-sized tRNAs by incorporating the precursor-derived splice junction phosphate into the mature tRNA as a canonical 3',5'-phosphodiester. May act as an RNA ligase with broad substrate specificity, and may function toward other RNAs.
messages: Cytoplasm
messages: Ligation probably proceeds through 3 nucleotidyl transfer steps, with 2',3'-cyclic phosphate termini being hydrolyzed to 3'-P termini in a step that precedes 3'-P activation with GMP. In the first nucleotidyl transfer step, RTCB reacts with GTP to form a covalent RTCB-histidine-GMP intermediate with release of PPi; in the second step, the GMP moiety is transferred to the RNA 3'-P; in the third step, the 5'-OH from the opposite RNA strand attacks the activated 3'-P to form a 3',5'-phosphodiester bond and release GMP.

230844:Edil3
gene id: 230844:Edil3
uniprot id: A0A6I9LKX1
uniprot id: A0A6I9LPY9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

230844:Lin28b
gene id: 230844:Lin28b
uniprot id: A0A6I9LRI2
uniprot id: A0A6J0DR94
names: Similarity
messages: Belongs to the lin-28 family.

230844:Esco2
gene id: 230844:Esco2
uniprot id: A0A6I9M3H3
names: Subcellular Location Annotation
messages: Nucleus

230844:Elovl1
gene id: 230844:Elovl1
uniprot id: A0A6J0CL66
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ELO family. ELOVL1 subfamily.
messages: Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that exhibits activity toward saturated C18 to C26 acyl-CoA substrates, with the highest activity towards C22:0 acyl-CoA. May participate to the production of both saturated and monounsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators. Important for saturated C24:0 and monounsaturated C24:1 sphingolipid synthesis. Indirectly inhibits RPE65 via production of VLCFAs.
messages: Endoplasmic reticulum membrane
messages: Interacts with LASS2, TECR and HSD17B12.
messages: Membrane
messages: The C-terminal di-lysine motif may confer endoplasmic reticulum localization.

230844:Tpd52l1
gene id: 230844:Tpd52l1
uniprot id: A0A6I9LEB0
uniprot id: A0A6I9LLK7
uniprot id: A0A6J0DJV4
uniprot id: A0A6J0DK22
names: Similarity
messages: Belongs to the TPD52 family.

230844:Cited1
gene id: 230844:Cited1
uniprot id: A0A6J0CPF2
uniprot id: A0A6J0CRK3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CITED family.
messages: Nucleus

230844:Hcn4
gene id: 230844:Hcn4
uniprot id: A0A6I9KUT5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the potassium channel HCN family.
messages: Cell membrane
messages: Membrane

230844:Rps19bp1
gene id: 230844:Rps19bp1
uniprot id: A0A6I9L8M3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AROS family.
messages: nucleolus

230844:Ralyl
gene id: 230844:Ralyl
uniprot id: A0A6J0D8W2
uniprot id: A0A6J0DAP0
uniprot id: A0A6J0DFL6
names: Similarity
messages: Belongs to the RRM HNRPC family. RALY subfamily.

230844:LOC102905774
gene id: 230844:LOC102905774
uniprot id: A0A6J0CQ89
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:LOC102909933
gene id: 230844:LOC102909933
uniprot id: A0A6I9LHE2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome P450 family.
messages: Endoplasmic reticulum membrane

230844:Prkrip1
gene id: 230844:Prkrip1
uniprot id: A0A6I9KUE5
names: Similarity
messages: Belongs to the PRKRIP1 family.

230844:Kcnj15
gene id: 230844:Kcnj15
uniprot id: A0A6J0DR37
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family.
messages: Membrane

230844:Ccdc86
gene id: 230844:Ccdc86
uniprot id: A0A6I9M0G0
names: Subcellular Location Annotation
messages: Nucleus

230844:Hacd2
gene id: 230844:Hacd2
uniprot id: A0A6I9L829
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the very long-chain fatty acids dehydratase HACD family.
messages: Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators.
messages: Endoplasmic reticulum membrane
messages: Membrane

230844:LOC102914234
gene id: 230844:LOC102914234
uniprot id: A0A6I9LKG0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome P450 family.
messages: Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.
messages: Endoplasmic reticulum membrane
messages: Microsome membrane

230844:Nrtn
gene id: 230844:Nrtn
uniprot id: A0A6I9LNL0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TGF-beta family. GDNF subfamily.
messages: Secreted

230844:Prom1
gene id: 230844:Prom1
uniprot id: A0A6J0DS76
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prominin family.
messages: Membrane
messages: microvillus membrane

230844:Tsn
gene id: 230844:Tsn
uniprot id: A0A6I9MAL3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the translin family.
messages: DNA-binding protein that specifically recognizes consensus sequences at the breakpoint junctions in chromosomal translocations, mostly involving immunoglobulin (Ig)/T-cell receptor gene segments. Seems to recognize single-stranded DNA ends generated by staggered breaks occurring at recombination hot spots.
messages: Exhibits both single-stranded and double-stranded endoribonuclease activity. May act as an activator of RNA-induced silencing complex (RISC) by facilitating endonucleolytic cleavage of the siRNA passenger strand.
messages: Nucleus
messages: Ring-shaped heterooctamer of six TSN and two TSNAX subunits, DNA/RNA binding occurs inside the ring.

230844:Ddc
gene id: 230844:Ddc
uniprot id: A0A6J0CWN6
names: Similarity
names: Subunit
messages: Belongs to the group II decarboxylase family.
messages: Homodimer.

230844:Rpl7
gene id: 230844:Rpl7
uniprot id: A0A6I9L8C9
names: Similarity
messages: Belongs to the universal ribosomal protein uL30 family.

230844:Ttc39b
gene id: 230844:Ttc39b
uniprot id: A0A6I9LB15
names: Similarity
messages: Belongs to the TTC39 family.

230844:LOC102911851
gene id: 230844:LOC102911851
uniprot id: A0A6I9M0I6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Toll-like receptor family.
messages: Membrane

230844:Med23
gene id: 230844:Med23
uniprot id: A0A6I9LMN2
uniprot id: A0A6I9M340
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Mediator complex subunit 23 family.
messages: Nucleus

230844:Vwa2
gene id: 230844:Vwa2
uniprot id: A0A6I9L7B8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

230844:Cacnb1
gene id: 230844:Cacnb1
uniprot id: A0A6I9KVJ0
uniprot id: A0A6I9L229
uniprot id: A0A6J0E551
uniprot id: A0A6J0E6U6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calcium channel beta subunit family.
messages: Membrane
messages: sarcolemma

230844:LOC102916430
gene id: 230844:LOC102916430
uniprot id: A0A6I9LPT7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PMG family.
messages: In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins.
messages: Interacts with hair keratins.

230844:Egflam
gene id: 230844:Egflam
uniprot id: A0A6I9L4V6
uniprot id: A0A6I9LDG8
uniprot id: A0A6I9LHC3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

230844:LOC102918871
gene id: 230844:LOC102918871
uniprot id: A0A6I9MP30
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Cpne3
gene id: 230844:Cpne3
uniprot id: A0A6J0DWJ9
names: Similarity
messages: Belongs to the copine family.

230844:Etv5
gene id: 230844:Etv5
uniprot id: A0A6I9LUA3
uniprot id: A0A6J0DWV5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

230844:LOC102926296
gene id: 230844:LOC102926296
uniprot id: A0A6I9LGZ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:LOC102918791
gene id: 230844:LOC102918791
uniprot id: A0A6J0DQP8
names: Function
names: Similarity
messages: Belongs to the prefoldin subunit beta family.
messages: Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins.

230844:Kif5c
gene id: 230844:Kif5c
uniprot id: A0A6I9LB24
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

230844:LOC102915344
gene id: 230844:LOC102915344
uniprot id: A0A6I9M6Y1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor T2R family.
messages: Membrane

230844:Gpr151
gene id: 230844:Gpr151
uniprot id: A0A6J0DAB7
names: Subcellular Location Annotation
messages: Membrane

230844:LOC102924167
gene id: 230844:LOC102924167
uniprot id: A0A6I9LZM9
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pentraxin family.
messages: Binds 2 calcium ions per subunit.
messages: Homopentamer. Pentaxin (or pentraxin) have a discoid arrangement of 5 non-covalently bound subunits.
messages: Secreted

230844:Itga6
gene id: 230844:Itga6
uniprot id: A0A6I9L3C8
uniprot id: A0A6I9L6W0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin alpha chain family.
messages: Membrane

230844:Tm7sf3
gene id: 230844:Tm7sf3
uniprot id: A0A6I9LML3
names: Subcellular Location Annotation
messages: Membrane

230844:LOC102918720
gene id: 230844:LOC102918720
uniprot id: A0A6I9M505
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:LOC102925562
gene id: 230844:LOC102925562
uniprot id: A0A6I9LE01
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

230844:LOC102920446
gene id: 230844:LOC102920446
uniprot id: A0A6I9LZN8
uniprot id: A0A6I9M405
names: Similarity
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. IRG family.

230844:Znf830
gene id: 230844:Znf830
uniprot id: A0A6I9M9X0
names: Subcellular Location Annotation
messages: Chromosome
messages: Nucleus speckle

230844:Cldn23
gene id: 230844:Cldn23
uniprot id: A0A6I9L6V8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Membrane
messages: tight junction

230844:Cdca7
gene id: 230844:Cdca7
uniprot id: A0A6I9KWM9
uniprot id: A0A6J0CLS5
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

230844:Slc25a45
gene id: 230844:Slc25a45
uniprot id: A0A6I9LLB9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

230844:LOC102912971
gene id: 230844:LOC102912971
uniprot id: A0A6J0CX04
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Membrane
messages: tight junction

230844:Tub
gene id: 230844:Tub
uniprot id: A0A6I9L8U6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TUB family.
messages: Secreted

230844:Bloc1s3
gene id: 230844:Bloc1s3
uniprot id: A0A6I9M9M1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BLOC1S3 family.
messages: Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO).
messages: Cytoplasm

230844:LOC102922433
gene id: 230844:LOC102922433
uniprot id: A0A6I9L445
uniprot id: A0A6J0CVM3
names: Subcellular Location Annotation
messages: Golgi apparatus membrane
messages: Membrane

230844:LOC102920532
gene id: 230844:LOC102920532
uniprot id: A0A6J0DGC8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ubiquitin family. SUMO subfamily.
messages: Nucleus

230844:LOC102922311
gene id: 230844:LOC102922311
uniprot id: A0A6I9KV43
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

230844:Ntf4
gene id: 230844:Ntf4
uniprot id: A0A6J0DY87
names: Similarity
messages: Belongs to the NGF-beta family.

230844:Ehd2
gene id: 230844:Ehd2
uniprot id: A0A6I9MC89
names: Subcellular Location Annotation
messages: Cell membrane
messages: Endosome membrane
messages: Membrane

230844:LOC102917321
gene id: 230844:LOC102917321
uniprot id: A0A6J0DF67
names: Function
names: Similarity
messages: Belongs to the eIF-1A family.
messages: Component of the 43S pre-initiation complex (43S PIC), which binds to the mRNA cap-proximal region, scans mRNA 5'-untranslated region, and locates the initiation codon. This protein enhances formation of the cap-proximal complex. Together with EIF1, facilitates scanning, start codon recognition, promotion of the assembly of 48S complex at the initiation codon (43S PIC becomes 48S PIC after the start codon is reached), and dissociation of aberrant complexes. After start codon location, together with EIF5B orients the initiator methionine-tRNA in a conformation that allows 60S ribosomal subunit joining to form the 80S initiation complex. Is released after 80S initiation complex formation, just after GTP hydrolysis by EIF5B, and before release of EIF5B. Its globular part is located in the A site of the 40S ribosomal subunit. Its interaction with EIF5 during scanning contribute to the maintenance of EIF1 within the open 43S PIC. In contrast to yeast orthologs, does not bind EIF1.

230844:LOC102923238
gene id: 230844:LOC102923238
uniprot id: A0A6I9M3F9
uniprot id: A0A6J0E4S4
names: Subcellular Location Annotation
messages: Secreted

230844:LOC107400684
gene id: 230844:LOC107400684
uniprot id: A0A6J0CW99
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

230844:LOC102905226
gene id: 230844:LOC102905226
uniprot id: A0A6I9M0Q7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SOSS-C family.
messages: Component of the SOSS complex, a multiprotein complex that functions downstream of the MRN complex to promote DNA repair and G2/M checkpoint. The SOSS complex associates with single-stranded DNA at DNA lesions and influences diverse endpoints in the cellular DNA damage response including cell-cycle checkpoint activation, recombinational repair and maintenance of genomic stability. Required for efficient homologous recombination-dependent repair of double-strand breaks (DSBs).
messages: Component of the SOSS complex.
messages: Nucleus

230844:Kdm3a
gene id: 230844:Kdm3a
uniprot id: A0A6I9LV99
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the JHDM2 histone demethylase family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Histone demethylase that specifically demethylates 'Lys-9' of histone H3, thereby playing a central role in histone code.
messages: Leu-Xaa-Xaa-Leu-Leu (LXXLL) motifs are known to mediate the association with nuclear receptors.
messages: Nucleus
messages: The JmjC domain and the C6-type zinc-finger are required for the demethylation activity.

230844:Fam149a
gene id: 230844:Fam149a
uniprot id: A0A6J0DEF5
names: Similarity
messages: Belongs to the FAM149 family.

230844:Cmtm8
gene id: 230844:Cmtm8
uniprot id: A0A6I9KYX9
names: Subcellular Location Annotation
messages: Membrane

230844:Mios
gene id: 230844:Mios
uniprot id: A0A6I9LMZ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat mio family.
messages: Lysosome membrane

230844:Aff4
gene id: 230844:Aff4
uniprot id: A0A6I9MBG7
uniprot id: A0A6I9MFK4
names: Similarity
messages: Belongs to the AF4 family.

230844:Zgpat
gene id: 230844:Zgpat
uniprot id: A0A6I9M947
names: Subcellular Location Annotation
names: Subunit
messages: Interacts with CHD4/Mi-2; the interaction is direct.
messages: Nucleus

230844:Prdx2
gene id: 230844:Prdx2
uniprot id: A0A6I9MQ68
names: Function
names: Similarity
messages: Belongs to the peroxiredoxin family.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively.

230844:Hapln4
gene id: 230844:Hapln4
uniprot id: A0A6I9M3D4
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

230844:LOC102918094
gene id: 230844:LOC102918094
uniprot id: A0A6I9LZN3
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

230844:Cblc
gene id: 230844:Cblc
uniprot id: A0A6I9M239
uniprot id: A0A6J0CQI0
names: Domain
names: Function
messages: E3 ubiquitin-protein ligase which accepts ubiquitin from specific E2 ubiquitin-conjugating enzymes, and transfers it to substrates, generally promoting their degradation by the proteasome.
messages: The N-terminus is composed of the phosphotyrosine binding (PTB) domain, a short linker region and the RING-type zinc finger. The PTB domain, which is also called TKB (tyrosine kinase binding) domain, is composed of three different subdomains: a four-helix bundle (4H), a calcium-binding EF hand and a divergent SH2 domain.

230844:Nos1
gene id: 230844:Nos1
uniprot id: A0A6I9L069
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NOS family.
messages: dendritic spine
messages: sarcolemma

230844:Ube2l6
gene id: 230844:Ube2l6
uniprot id: A0A6I9LSR2
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

230844:Csf3
gene id: 230844:Csf3
uniprot id: A0A6I9KVT2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IL-6 superfamily.
messages: Granulocyte/macrophage colony-stimulating factors are cytokines that act in hematopoiesis by controlling the production, differentiation, and function of 2 related white cell populations of the blood, the granulocytes and the monocytes-macrophages. This CSF induces granulocytes.
messages: Secreted

230844:Shbg
gene id: 230844:Shbg
uniprot id: A0A6I9L942
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

230844:Akr1e2
gene id: 230844:Akr1e2
uniprot id: A0A6I9M1J5
names: Similarity
messages: Belongs to the aldo/keto reductase family.

230844:Rhbdf2
gene id: 230844:Rhbdf2
uniprot id: A0A6I9M756
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S54 family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Regulates ADAM17 protease, a sheddase of the epidermal growth factor (EGF) receptor ligands and TNF, thereby plays a role in sleep, cell survival, proliferation, migration and inflammation. Does not exhibit any protease activity on its own.

230844:Gal3st1
gene id: 230844:Gal3st1
uniprot id: A0A6J0CW52
names: Similarity
messages: Belongs to the galactose-3-O-sulfotransferase family.

230844:Kcnc1
gene id: 230844:Kcnc1
uniprot id: A0A6I9M6W1
uniprot id: A0A6J0CLG3
names: Subcellular Location Annotation
messages: Membrane

230844:Spata6
gene id: 230844:Spata6
uniprot id: A0A6I9LEP6
names: Similarity
messages: Belongs to the SPATA6 family.

230844:F8
gene id: 230844:F8
uniprot id: A0A6I9MNL7
names: Similarity
messages: Belongs to the multicopper oxidase family.

230844:LOC102906097
gene id: 230844:LOC102906097
uniprot id: A0A6I9MMD5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Bckdha
gene id: 230844:Bckdha
uniprot id: A0A6I9M606
names: Function
names: Similarity
messages: Belongs to the BCKDHA family.
messages: Together with BCKDHB forms the heterotetrameric E1 subunit of the mitochondrial branched-chain alpha-ketoacid dehydrogenase (BCKD) complex. The BCKD complex catalyzes the multi-step oxidative decarboxylation of alpha-ketoacids derived from the branched-chain amino-acids valine, leucine and isoleucine producing CO2 and acyl-CoA which is subsequently utilized to produce energy. The E1 subunit catalyzes the first step with the decarboxylation of the alpha-ketoacid forming an enzyme-product intermediate. A reductive acylation mediated by the lipoylamide cofactor of E2 extracts the acyl group from the E1 active site for the next step of the reaction.

230844:LOC102925935
gene id: 230844:LOC102925935
uniprot id: A0A6I9M9E1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Foxn3
gene id: 230844:Foxn3
uniprot id: A0A6J0DZS5
uniprot id: A0A6J0E134
uniprot id: A0A6J0E138
uniprot id: A0A6J0E2H8
uniprot id: A0A6J0E652
names: Function
names: Subcellular Location Annotation
messages: Acts as a transcriptional repressor. May be involved in DNA damage-inducible cell cycle arrests (checkpoints).
messages: Nucleus

230844:Pla2g2e
gene id: 230844:Pla2g2e
uniprot id: A0A6I9LLT0
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phospholipase A2 family.
messages: Binds 1 Ca(2+) ion per subunit.
messages: Secreted

230844:LOC102909250
gene id: 230844:LOC102909250
uniprot id: A0A6I9L0E3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:LOC102929138
gene id: 230844:LOC102929138
uniprot id: A0A6I9LP54
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 14-3-3 family.
messages: Cytoplasm

230844:B3galt1
gene id: 230844:B3galt1
uniprot id: A0A6J0CK34
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane

230844:Chpf
gene id: 230844:Chpf
uniprot id: A0A6I9KW22
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chondroitin N-acetylgalactosaminyltransferase family.
messages: Golgi stack membrane
messages: Membrane

230844:Catsperd
gene id: 230844:Catsperd
uniprot id: A0A6J0DN68
names: Similarity
messages: Belongs to the CATSPERD family.

230844:Rab32
gene id: 230844:Rab32
uniprot id: A0A6I9LSU9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Membrane
messages: The small GTPases Rab are key regulators in vesicle trafficking.

230844:Defb129
gene id: 230844:Defb129
uniprot id: A0A6I9LVT3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the beta-defensin family.
messages: Has antibacterial activity.
messages: Secreted

230844:Tll1
gene id: 230844:Tll1
uniprot id: A0A6I9LP28
names: Caution
names: Cofactor
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

230844:Emc7
gene id: 230844:Emc7
uniprot id: A0A6I9M4Q8
names: Similarity
names: Subunit
messages: Belongs to the EMC7 family.
messages: Component of the ER membrane protein complex (EMC).

230844:Asic3
gene id: 230844:Asic3
uniprot id: A0A6I9M597
names: Subcellular Location Annotation
messages: Membrane

230844:Acad9
gene id: 230844:Acad9
uniprot id: A0A6I9KU29
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

230844:Ppp2r2b
gene id: 230844:Ppp2r2b
uniprot id: A0A6I9L5V8
uniprot id: A0A6I9LES6
uniprot id: A0A6J0DAU6
names: Similarity
messages: Belongs to the phosphatase 2A regulatory subunit B family.

230844:Sez6
gene id: 230844:Sez6
uniprot id: A0A6I9L6M6
uniprot id: A0A6I9LE88
uniprot id: A0A6J0DAA5
uniprot id: A0A6J0DEK7
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

230844:Esrrg
gene id: 230844:Esrrg
uniprot id: A0A6J0EAG2
uniprot id: A0A6J0EGB2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR3 subfamily.
messages: Nucleus

230844:LOC102914150
gene id: 230844:LOC102914150
uniprot id: A0A6I9M3L3
uniprot id: A0A6J0DZZ3
names: Function
names: Similarity
messages: Belongs to the phospholipid scramblase family.
messages: May mediate accelerated ATP-independent bidirectional transbilayer migration of phospholipids upon binding calcium ions that results in a loss of phospholipid asymmetry in the plasma membrane.

230844:Ech1
gene id: 230844:Ech1
uniprot id: A0A6I9LN01
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

230844:Btn1a1
gene id: 230844:Btn1a1
uniprot id: A0A6I9MAE7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the immunoglobulin superfamily. BTN/MOG family.
messages: Membrane

230844:Aup1
gene id: 230844:Aup1
uniprot id: A0A6I9MFE1
uniprot id: A0A6J0CKG1
uniprot id: A0A6J0CL84
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AUP1 family.
messages: Membrane

230844:LOC102927649
gene id: 230844:LOC102927649
uniprot id: A0A6I9LZ82
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Pacs2
gene id: 230844:Pacs2
uniprot id: A0A6J0E167
uniprot id: A0A6J0E4H1
uniprot id: A0A6J0E656
names: Similarity
messages: Belongs to the PACS family.

230844:LOC102911629
gene id: 230844:LOC102911629
uniprot id: A0A6I9M559
uniprot id: A0A6J0E746
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:LOC102906400
gene id: 230844:LOC102906400
uniprot id: A0A6I9MEU0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:LOC102908787
gene id: 230844:LOC102908787
uniprot id: A0A6I9LG93
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the intercrine beta (chemokine CC) family.
messages: Secreted

230844:LOC102905547
gene id: 230844:LOC102905547
uniprot id: A0A6I9M8E9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PMG family.
messages: In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins.
messages: Interacts with hair keratins.

230844:LOC102926083
gene id: 230844:LOC102926083
uniprot id: A0A6J0CTM3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MHC class I family.
messages: Membrane

230844:Ptafr
gene id: 230844:Ptafr
uniprot id: A0A6J0D4W8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Interacts with ARRB1.
messages: Membrane
messages: Receptor for platelet activating factor, a chemotactic phospholipid mediator that possesses potent inflammatory, smooth-muscle contractile and hypotensive activity. Seems to mediate its action via a G protein that activates a phosphatidylinositol-calcium second messenger system.

230844:LOC102917229
gene id: 230844:LOC102917229
uniprot id: A0A6I9MMF7
names: Similarity
messages: Belongs to the OSBP family.

230844:LOC102903776
gene id: 230844:LOC102903776
uniprot id: A0A6J0CR48
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Impg1
gene id: 230844:Impg1
uniprot id: A0A6I9LNX9
names: Subcellular Location Annotation
messages: interphotoreceptor matrix

230844:Gbx2
gene id: 230844:Gbx2
uniprot id: A0A6I9M715
names: Subcellular Location Annotation
messages: Nucleus

230844:Slc66a2
gene id: 230844:Slc66a2
uniprot id: A0A6I9L6G3
uniprot id: A0A6I9LA31
names: Subcellular Location Annotation
messages: Membrane

230844:LOC102915382
gene id: 230844:LOC102915382
uniprot id: A0A6I9LJ50
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
messages: Endoplasmic reticulum

230844:Dok6
gene id: 230844:Dok6
uniprot id: A0A6I9M446
names: Similarity
messages: Belongs to the DOK family. Type B subfamily.

230844:LOC102906109
gene id: 230844:LOC102906109
uniprot id: A0A6I9LR56
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

230844:LOC102925812
gene id: 230844:LOC102925812
uniprot id: A0A6I9M1J2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2A family.
messages: Chromosome
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

230844:Recql
gene id: 230844:Recql
uniprot id: A0A6I9LC08
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the helicase family. RecQ subfamily.
messages: Nucleus

230844:Tfe3
gene id: 230844:Tfe3
uniprot id: A0A6I9MPJ1
uniprot id: A0A6I9MQJ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MiT/TFE family.
messages: Nucleus

230844:LOC102906341
gene id: 230844:LOC102906341
uniprot id: A0A6I9M993
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Tax1bp3
gene id: 230844:Tax1bp3
uniprot id: A0A6I9M3N4
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: Cytoplasm
messages: May regulate a number of protein-protein interactions by competing for PDZ domain binding sites.
messages: Nucleus

230844:Dtd1
gene id: 230844:Dtd1
uniprot id: A0A6J0DZP8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DTD family.
messages: Cytoplasm

230844:LOC102923429
gene id: 230844:LOC102923429
uniprot id: A0A6J0EAU1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:LOC102918708
gene id: 230844:LOC102918708
uniprot id: A0A6I9LYX9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Il2rg
gene id: 230844:Il2rg
uniprot id: A0A6I9LCB3
uniprot id: A0A6J0DJH9
names: Subcellular Location Annotation
messages: Membrane

230844:Slc5a12
gene id: 230844:Slc5a12
uniprot id: A0A6I9LDF2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Cell membrane
messages: Membrane

230844:Yif1b
gene id: 230844:Yif1b
uniprot id: A0A6I9LFQ5
uniprot id: A0A6I9LN15
uniprot id: A0A6I9LTS5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YIF1 family.
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Has a role in transport between endoplasmic reticulum and Golgi.
messages: Membrane

230844:Efna5
gene id: 230844:Efna5
uniprot id: A0A6I9M551
uniprot id: A0A6I9MG86
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ephrin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

230844:LOC102910392
gene id: 230844:LOC102910392
uniprot id: A0A6I9LXS5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Tpmt
gene id: 230844:Tpmt
uniprot id: A0A6I9KXL5
names: Similarity
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TPMT family.
messages: Monomer.

230844:LOC102915717
gene id: 230844:LOC102915717
uniprot id: A0A6I9M0E4
names: Similarity
messages: Belongs to the serpin family.

230844:Plppr5
gene id: 230844:Plppr5
uniprot id: A0A6I9L7F4
uniprot id: A0A6I9LF64
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PA-phosphatase related phosphoesterase family.
messages: Membrane

230844:LOC107402149
gene id: 230844:LOC107402149
uniprot id: A0A6J0DRC5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDK2AP family.
messages: Nucleus

230844:LOC102910486
gene id: 230844:LOC102910486
uniprot id: A0A6I9M1Q2
names: Function
names: Subunit
messages: In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins.
messages: Interacts with hair keratins.

230844:Ciao1
gene id: 230844:Ciao1
uniprot id: A0A6I9LQ46
names: Function
names: Similarity
names: Subunit
messages: Belongs to the WD repeat CIA1 family.
messages: Component of the CIA complex. Component of the MMXD complex, which includes CIAO1, ERCC2, FAM96B, MMS19 and SLC25A5. Interacts with WT1. Interacts with FAM96A.
messages: Key component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into extramitochondrial Fe/S proteins. Seems to specifically modulate the transactivation activity of WT1. As part of the mitotic spindle-associated MMXD complex it may play a role in chromosome segregation.

230844:Mex3d
gene id: 230844:Mex3d
uniprot id: A0A6J0DBZ0
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

230844:Slc8a3
gene id: 230844:Slc8a3
uniprot id: A0A6I9KXS6
uniprot id: A0A6I9L4Q5
uniprot id: A0A6J0CYG2
uniprot id: A0A6J0D196
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. SLC8 subfamily.
messages: Cell membrane
messages: Membrane

230844:Ppm1b
gene id: 230844:Ppm1b
uniprot id: A0A6I9LQ86
uniprot id: A0A6I9LXN2
uniprot id: A0A6I9LY28
uniprot id: A0A6I9M2Q0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PP2C family.
messages: Membrane
messages: cytosol

230844:Esrra
gene id: 230844:Esrra
uniprot id: A0A6I9LKL8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR3 subfamily.
messages: Nucleus

230844:Tacc3
gene id: 230844:Tacc3
uniprot id: A0A6I9L4M5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACC family.
messages: centrosome

230844:Tut1
gene id: 230844:Tut1
uniprot id: A0A6I9MEC0
names: Similarity
messages: Belongs to the DNA polymerase type-B-like family.

230844:Cdkn3
gene id: 230844:Cdkn3
uniprot id: A0A6I9LSL8
uniprot id: A0A6I9M0Q5
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family.

230844:Nceh1
gene id: 230844:Nceh1
uniprot id: A0A6I9KU86
names: Similarity
messages: Belongs to the 'GDXG' lipolytic enzyme family.

230844:Krtcap2
gene id: 230844:Krtcap2
uniprot id: A0A6I9L4B9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KRTCAP2 family.
messages: Membrane

230844:LOC102915862
gene id: 230844:LOC102915862
uniprot id: A0A6I9L672
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tollip family.
messages: Cytoplasm

230844:Rangrf
gene id: 230844:Rangrf
uniprot id: A0A6I9L5V7
names: Similarity
messages: Belongs to the MOG1 family.

230844:Psma4
gene id: 230844:Psma4
uniprot id: A0A6I9L1W4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1A family.
messages: Component of the 20S core proteasome complex involved in the proteolytic degradation of most intracellular proteins. This complex plays numerous essential roles within the cell by associating with different regulatory particles. Associated with two 19S regulatory particles, forms the 26S proteasome and thus participates in the ATP-dependent degradation of ubiquitinated proteins. The 26S proteasome plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins that could impair cellular functions, and by removing proteins whose functions are no longer required. Associated with the PA200 or PA28, the 20S proteasome mediates ubiquitin-independent protein degradation. This type of proteolysis is required in several pathways including spermatogenesis (20S-PA200 complex) or generation of a subset of MHC class I-presented antigenic peptides (20S-PA28 complex).
messages: Cytoplasm
messages: Nucleus
messages: The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits.

230844:Parp10
gene id: 230844:Parp10
uniprot id: A0A6I9M8E3
uniprot id: A0A6J0E7Y1
names: Similarity
messages: Belongs to the ARTD/PARP family.

230844:LOC102924837
gene id: 230844:LOC102924837
uniprot id: A0A6I9L3Q4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alpha/beta interferon family.
messages: Secreted

230844:Rbm15b
gene id: 230844:Rbm15b
uniprot id: A0A6I9L8G9
names: Similarity
messages: Belongs to the RRM Spen family.

230844:Ddi1
gene id: 230844:Ddi1
uniprot id: A0A6I9LHE1
names: Similarity
messages: Belongs to the DDI1 family.

230844:Tbx6
gene id: 230844:Tbx6
uniprot id: A0A6I9LH90
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

230844:Crh
gene id: 230844:Crh
uniprot id: A0A6I9L124
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sauvagine/corticotropin-releasing factor/urotensin I family.
messages: Secreted

230844:Mettl1
gene id: 230844:Mettl1
uniprot id: A0A6I9KYG6
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
messages: Forms a complex with WDR4.
messages: Nucleus
messages: Phosphorylation at Ser-20 inactivates its catalytic activity but does not affect the interaction with WDR4.

230844:Arid2
gene id: 230844:Arid2
uniprot id: A0A6I9LB57
names: Subcellular Location Annotation
messages: Nucleus

230844:LOC102907684
gene id: 230844:LOC102907684
uniprot id: A0A6J0E422
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: Potential calcium-dependent cell-adhesion protein. May be involved in the establishment and maintenance of specific neuronal connections in the brain.

230844:Mycl
gene id: 230844:Mycl
uniprot id: A0A6I9MDQ7
uniprot id: A0A6J0CFS2
names: Subcellular Location Annotation
names: Subunit
messages: Efficient DNA binding requires dimerization with another bHLH protein.
messages: Nucleus

230844:Sptlc3
gene id: 230844:Sptlc3
uniprot id: A0A6I9LRE0
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.

230844:Med13l
gene id: 230844:Med13l
uniprot id: A0A6I9KU38
uniprot id: A0A6I9KZZ6
uniprot id: A0A6I9L311
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 13 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex, which is composed of MED1, MED4, MED6, MED7, MED8, MED9, MED10, MED11, MED12, MED13, MED13L, MED14, MED15, MED16, MED17, MED18, MED19, MED20, MED21, MED22, MED23, MED24, MED25, MED26, MED27, MED29, MED30, MED31, CCNC, CDK8 and CDC2L6/CDK11. The MED12, MED13, CCNC and CDK8 subunits form a distinct module termed the CDK8 module. Mediator containing the CDK8 module is less active than Mediator lacking this module in supporting transcriptional activation. Individual preparations of the Mediator complex lacking one or more distinct subunits have been variously termed ARC, CRSP, DRIP, PC2, SMCC and TRAP.
messages: Nucleus

230844:Cript
gene id: 230844:Cript
uniprot id: A0A6I9M2N9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CRIPT family.
messages: Cytoplasm

230844:Hs3st5
gene id: 230844:Hs3st5
uniprot id: A0A6J0DQU6
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

230844:Kcnh2
gene id: 230844:Kcnh2
uniprot id: A0A6I9MCF9
uniprot id: A0A6I9MGF1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the potassium channel family. H (Eag) (TC 1.A.1.20) subfamily. Kv11.1/KCNH2 sub-subfamily.
messages: Membrane

230844:Gpx5
gene id: 230844:Gpx5
uniprot id: A0A6I9M222
uniprot id: A0A6J0E3C2
names: Similarity
messages: Belongs to the glutathione peroxidase family.

230844:St18
gene id: 230844:St18
uniprot id: A0A6J0CL62
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MYT1 family.
messages: Nucleus

230844:LOC102909169
gene id: 230844:LOC102909169
uniprot id: A0A6I9M869
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Pou4f3
gene id: 230844:Pou4f3
uniprot id: A0A6I9LEH6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the POU transcription factor family.
messages: Nucleus

230844:Zdhhc24
gene id: 230844:Zdhhc24
uniprot id: A0A6I9LCX3
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

230844:Lipn
gene id: 230844:Lipn
uniprot id: A0A6I9LS26
names: Similarity
messages: Belongs to the AB hydrolase superfamily. Lipase family.

230844:LOC102921228
gene id: 230844:LOC102921228
uniprot id: A0A6I9MKY5
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

230844:LOC102909587
gene id: 230844:LOC102909587
uniprot id: A0A6I9MJM3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Lrp2
gene id: 230844:Lrp2
uniprot id: A0A6J0CKN5
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LDLR family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

230844:Hip1
gene id: 230844:Hip1
uniprot id: A0A6I9L465
uniprot id: A0A6J0DRH6
uniprot id: A0A6J0DXB7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLA2 family.
messages: Membrane

230844:Casr
gene id: 230844:Casr
uniprot id: A0A6I9L334
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

230844:Satb2
gene id: 230844:Satb2
uniprot id: A0A6I9L8R3
uniprot id: A0A6J0D287
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CUT homeobox family.
messages: Nucleus

230844:Ppl
gene id: 230844:Ppl
uniprot id: A0A6I9LIU9
names: Similarity
messages: Belongs to the plakin or cytolinker family.

230844:LOC102910282
gene id: 230844:LOC102910282
uniprot id: A0A6J0E8S6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Wnt9b
gene id: 230844:Wnt9b
uniprot id: A0A6I9L2G8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

230844:Tbcc
gene id: 230844:Tbcc
uniprot id: A0A6I9M758
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TBCC family.
messages: Cytoplasm
messages: Supercomplex made of cofactors A to E. Cofactors A and D function by capturing and stabilizing tubulin in a quasi-native conformation. Cofactor E binds to the cofactor D-tubulin complex; interaction with cofactor C then causes the release of tubulin polypeptides that are committed to the native state.

230844:Pard3
gene id: 230844:Pard3
uniprot id: A0A6I9LEZ4
uniprot id: A0A6I9LEZ8
uniprot id: A0A6I9LGP0
uniprot id: A0A6I9LGP7
uniprot id: A0A6I9LP08
uniprot id: A0A6I9LP13
uniprot id: A0A6I9LQ74
uniprot id: A0A6I9LUU0
uniprot id: A0A6J0DKW9
uniprot id: A0A6J0DKX4
uniprot id: A0A6J0DN60
uniprot id: A0A6J0DNH6
uniprot id: A0A6J0DNZ3
uniprot id: A0A6J0DUP6
uniprot id: A0A6J0DUP9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAR3 family.
messages: Cell junction
messages: Endomembrane system

230844:Ormdl3
gene id: 230844:Ormdl3
uniprot id: A0A6J0E4J3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ORM family.
messages: Membrane
messages: Negative regulator of sphingolipid synthesis.

230844:Erbb4
gene id: 230844:Erbb4
uniprot id: A0A6I9M3Y7
uniprot id: A0A6J0E7I2
uniprot id: A0A6J0E980
uniprot id: A0A6J0EBH3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. EGF receptor subfamily.
messages: Membrane

230844:Fam13c
gene id: 230844:Fam13c
uniprot id: A0A6I9L8E2
uniprot id: A0A6I9LHX5
uniprot id: A0A6J0DJD4
names: Similarity
messages: Belongs to the FAM13 family.

230844:Ubxn1
gene id: 230844:Ubxn1
uniprot id: A0A6I9MA92
names: Subcellular Location Annotation
messages: Cytoplasm

230844:Prm1
gene id: 230844:Prm1
uniprot id: A0A6I9LXE6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protamine P1 family.
messages: Chromosome
messages: Nucleus
messages: Protamines substitute for histones in the chromatin of sperm during the haploid phase of spermatogenesis. They compact sperm DNA into a highly condensed, stable and inactive complex.

230844:Slc18a1
gene id: 230844:Slc18a1
uniprot id: A0A6I9M4T8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Vesicular transporter family.
messages: Membrane
messages: secretory vesicle membrane
messages: synaptic vesicle membrane

230844:Alg14
gene id: 230844:Alg14
uniprot id: A0A6I9L7G4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ALG14 family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Nucleus membrane

230844:Glra2
gene id: 230844:Glra2
uniprot id: A0A6I9KY90
uniprot id: A0A6I9L8J2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synapse
messages: Synaptic cell membrane

230844:Lsm2
gene id: 230844:Lsm2
uniprot id: A0A6I9M3M5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the snRNP Sm proteins family.
messages: Binds specifically to the 3'-terminal U-tract of U6 snRNA.
messages: Nucleus

230844:Sstr4
gene id: 230844:Sstr4
uniprot id: A0A6I9LKN7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

230844:LOC102913700
gene id: 230844:LOC102913700
uniprot id: A0A6I9L901
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

230844:LOC102910380
gene id: 230844:LOC102910380
uniprot id: A0A6J0DY23
names: Similarity
messages: Belongs to the universal ribosomal protein uL14 family.

230844:Slc11a1
gene id: 230844:Slc11a1
uniprot id: A0A6I9L3A0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NRAMP family.
messages: Endosome membrane
messages: Late endosome membrane
messages: Lysosome membrane

230844:LOC102923976
gene id: 230844:LOC102923976
uniprot id: A0A6J0CYT2
names: Similarity
messages: Belongs to the glycosyl hydrolase 22 family.

230844:Tp63
gene id: 230844:Tp63
uniprot id: A0A6I9LUD5
uniprot id: A0A6I9LV32
uniprot id: A0A6I9LZH4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a sequence specific DNA binding transcriptional activator or repressor. The isoforms contain a varying set of transactivation and auto-regulating transactivation inhibiting domains thus showing an isoform specific activity. May be required in conjunction with TP73/p73 for initiation of p53/TP53 dependent apoptosis in response to genotoxic insults and the presence of activated oncogenes.
messages: Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression.
messages: Belongs to the p53 family.
messages: Binds 1 zinc ion per subunit.
messages: Binds DNA as a homotetramer.
messages: Binds DNA as a homotetramer. Isoform composition of the tetramer may determine transactivation activity.
messages: Cytoplasm
messages: Nucleus

230844:LOC102914800
gene id: 230844:LOC102914800
uniprot id: A0A6I9MG63
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the intercrine alpha (chemokine CxC) family.
messages: Secreted

230844:Hyal3
gene id: 230844:Hyal3
uniprot id: A0A6I9L736
names: Similarity
messages: Belongs to the glycosyl hydrolase 56 family.

230844:Srpx
gene id: 230844:Srpx
uniprot id: A0A6I9LCX7
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

230844:Csf3r
gene id: 230844:Csf3r
uniprot id: A0A6I9LA88
uniprot id: A0A6J0DEI9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type I cytokine receptor family. Type 2 subfamily.
messages: Membrane

230844:Nmt1
gene id: 230844:Nmt1
uniprot id: A0A6I9L2I9
names: Function
names: Similarity
messages: Adds a myristoyl group to the N-terminal glycine residue of certain cellular proteins.
messages: Belongs to the NMT family.

230844:Anapc11
gene id: 230844:Anapc11
uniprot id: A0A6I9LZT9
names: Similarity
messages: Belongs to the RING-box family.

230844:Lck
gene id: 230844:Lck
uniprot id: A0A6I9M8M8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.
messages: Cell membrane
messages: Membrane
messages: cytosol

230844:Pon2
gene id: 230844:Pon2
uniprot id: A0A6I9LYG8
names: Cofactor
names: PTM
names: Similarity
messages: Belongs to the paraoxonase family.
messages: Binds 2 calcium ions per subunit.
messages: Glycosylated.

230844:Lig3
gene id: 230844:Lig3
uniprot id: A0A6I9LYK2
uniprot id: A0A6I9M5R4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP-dependent DNA ligase family.
messages: Nucleus

230844:Cdh20
gene id: 230844:Cdh20
uniprot id: A0A6I9MCA0
names: Function
names: Subcellular Location Annotation
messages: Cadherins are calcium-dependent cell adhesion proteins.
messages: Cell membrane
messages: Membrane

230844:Slc35a1
gene id: 230844:Slc35a1
uniprot id: A0A6I9L1Q2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleotide-sugar transporter family. SLC35A subfamily.
messages: Golgi apparatus membrane
messages: Membrane

230844:Itgb2
gene id: 230844:Itgb2
uniprot id: A0A6I9M2Z3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin beta chain family.
messages: Cell membrane
messages: Membrane
messages: Membrane raft

230844:LOC102904838
gene id: 230844:LOC102904838
uniprot id: A0A6I9M5B8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:LOC102922048
gene id: 230844:LOC102922048
uniprot id: A0A6I9MIR3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Tob2
gene id: 230844:Tob2
uniprot id: A0A6I9LPA4
names: Similarity
messages: Belongs to the BTG family.

230844:Lpar5
gene id: 230844:Lpar5
uniprot id: A0A6I9M379
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

230844:Map3k13
gene id: 230844:Map3k13
uniprot id: A0A6I9LT34
names: Similarity
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.

230844:Cavin3
gene id: 230844:Cavin3
uniprot id: A0A6I9M905
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CAVIN family.
messages: caveola

230844:Dync1i1
gene id: 230844:Dync1i1
uniprot id: A0A6I9LMY7
uniprot id: A0A6I9LR12
uniprot id: A0A6I9LYH3
uniprot id: A0A6I9LYY7
uniprot id: A0A6I9M3F8
uniprot id: A0A6J0E2J8
names: Similarity
messages: Belongs to the dynein intermediate chain family.

230844:Miga2
gene id: 230844:Miga2
uniprot id: A0A6I9LRY4
names: Similarity
messages: Belongs to the mitoguardin family.

230844:Dlgap4
gene id: 230844:Dlgap4
uniprot id: A0A6I9LI18
uniprot id: A0A6I9LXU3
names: Similarity
messages: Belongs to the SAPAP family.

230844:Skp1
gene id: 230844:Skp1
uniprot id: A0A6I9M1C6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SKP1 family.
messages: Component of multiple SCF (SKP1-CUL1-F-box) E3 ubiquitin-protein ligase complexes formed of CUL1, SKP1, RBX1 and a variable F-box domain-containing protein as substrate-specific subunit.
messages: Essential component of the SCF (SKP1-CUL1-F-box protein) ubiquitin ligase complex, which mediates the ubiquitination of proteins involved in cell cycle progression, signal transduction and transcription. In the SCF complex, serves as an adapter that links the F-box protein to CUL1.
messages: The functional specificity of the SCF complex depends on the F-box protein as substrate recognition component.

230844:LOC102908771
gene id: 230844:LOC102908771
uniprot id: A0A6I9LHV2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Got1
gene id: 230844:Got1
uniprot id: A0A6I9M323
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.
messages: In eukaryotes there are cytoplasmic, mitochondrial and chloroplastic isozymes.

230844:Tacstd2
gene id: 230844:Tacstd2
uniprot id: A0A6I9M1Y4
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPCAM family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

230844:Slc2a3
gene id: 230844:Slc2a3
uniprot id: A0A6I9MEM9
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. Glucose transporter subfamily.
messages: Cell membrane
messages: Cell projection
messages: Facilitative glucose transporter that can also mediate the uptake of various other monosaccharides across the cell membrane. Mediates the uptake of glucose, 2-deoxyglucose, galactose, mannose, xylose and fucose, and probably also dehydroascorbate. Does not mediate fructose transport.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Perikaryon
messages: Transport is mediated via a series of conformation changes, switching between a conformation where the substrate-binding cavity is accessible from the outside, and a another conformation where it is accessible from the cytoplasm.

230844:Eda
gene id: 230844:Eda
uniprot id: A0A6I9LCD1
uniprot id: A0A6I9LE43
uniprot id: A0A6I9LLE8
uniprot id: A0A6I9LMH3
names: Similarity
messages: Belongs to the tumor necrosis factor family.

230844:Krt222
gene id: 230844:Krt222
uniprot id: A0A6I9KVW4
names: Similarity
messages: Belongs to the intermediate filament family.

230844:LOC102909967
gene id: 230844:LOC102909967
uniprot id: A0A6I9M3K0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the somatotropin/prolactin family.
messages: Secreted

230844:Tafa3
gene id: 230844:Tafa3
uniprot id: A0A6I9M2I3
names: Similarity
messages: Belongs to the TAFA family.

230844:Ndst2
gene id: 230844:Ndst2
uniprot id: A0A6I9LUG0
uniprot id: A0A6J0DV89
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 1 family. NDST subfamily.
messages: Membrane

230844:LOC102923159
gene id: 230844:LOC102923159
uniprot id: A0A6I9M9X7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Tshr
gene id: 230844:Tshr
uniprot id: A0A6I9LRX3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Basolateral cell membrane
messages: Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily.
messages: Cell membrane
messages: Lateral cell membrane
messages: Membrane
messages: Receptor for the thyroid-stimulating hormone (TSH) or thyrotropin. Also acts as a receptor for the heterodimeric glycoprotein hormone (GPHA2:GPHB5) or thyrostimulin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Plays a central role in controlling thyroid cell metabolism.

230844:Rbks
gene id: 230844:Rbks
uniprot id: A0A6I9LTS1
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.
messages: Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.
messages: Belongs to the carbohydrate kinase pfkB family.
messages: Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
messages: Cytoplasm
messages: Homodimer.
messages: Nucleus
messages: Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate.

230844:Rnf10
gene id: 230844:Rnf10
uniprot id: A0A6I9MIH6
uniprot id: A0A6I9MKP3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNF10 family.
messages: Cytoplasm

230844:Smarcd1
gene id: 230844:Smarcd1
uniprot id: A0A6I9L7T0
names: Similarity
messages: Belongs to the SMARCD family.

230844:Mfn1
gene id: 230844:Mfn1
uniprot id: A0A6I9L0L6
names: Subcellular Location Annotation
messages: Membrane
messages: Mitochondrion outer membrane

230844:Acan
gene id: 230844:Acan
uniprot id: A0A6J0D8L0
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aggrecan/versican proteoglycan family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

230844:LOC102914023
gene id: 230844:LOC102914023
uniprot id: A0A6I9M9R8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alpha/beta interferon family.
messages: Secreted

230844:Tppp3
gene id: 230844:Tppp3
uniprot id: A0A6I9LQV0
names: Similarity
messages: Belongs to the TPPP family.

230844:Myadml2
gene id: 230844:Myadml2
uniprot id: A0A6J0E3G6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MAL family.
messages: Membrane

230844:LOC102921883
gene id: 230844:LOC102921883
uniprot id: A0A6I9M7L2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Prkcb
gene id: 230844:Prkcb
uniprot id: A0A6I9LCE7
uniprot id: A0A6I9LKQ2
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.
messages: Binds 3 Ca(2+) ions per subunit. The ions are bound to the C2 domain.
messages: Cytoplasm
messages: Membrane
messages: Nucleus

230844:Rax
gene id: 230844:Rax
uniprot id: A0A6I9KRZ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the paired homeobox family. Bicoid subfamily.
messages: Nucleus

230844:Stard3nl
gene id: 230844:Stard3nl
uniprot id: A0A6I9LRJ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STARD3 family.
messages: Membrane

230844:Psmb10
gene id: 230844:Psmb10
uniprot id: A0A6I9LMW4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1B family.
messages: Component of the proteasome complex.
messages: Component of the proteasome, a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.
messages: Cytoplasm
messages: Nucleus

230844:Brpf1
gene id: 230844:Brpf1
uniprot id: A0A6I9MFA9
uniprot id: A0A6J0CT39
uniprot id: A0A6J0CTI2
uniprot id: A0A6J0CUM8
uniprot id: A0A6J0CV85
uniprot id: A0A6J0CV90
uniprot id: A0A6J0CXS5
names: Subcellular Location Annotation
messages: Nucleus

230844:Rps6ka2
gene id: 230844:Rps6ka2
uniprot id: A0A6I9L2R0
uniprot id: A0A6I9LEK7
uniprot id: A0A6J0D499
uniprot id: A0A6J0D5B4
uniprot id: A0A6J0D6E4
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily.

230844:Spire2
gene id: 230844:Spire2
uniprot id: A0A6J0E2R1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the spire family.
messages: Cell membrane
messages: Cytoplasmic vesicle membrane
messages: Membrane
messages: cytoskeleton

230844:Lin7b
gene id: 230844:Lin7b
uniprot id: A0A6I9LPP1
uniprot id: A0A6J0DWS5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Basolateral cell membrane
messages: Belongs to the lin-7 family.
messages: Cell membrane
messages: Lateral cell membrane
messages: Membrane
messages: Plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells.
messages: Postsynaptic density membrane
messages: tight junction

230844:Tm7sf2
gene id: 230844:Tm7sf2
uniprot id: A0A6I9LKI2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ERG4/ERG24 family.
messages: Membrane

230844:Cpsf4
gene id: 230844:Cpsf4
uniprot id: A0A6I9LFA2
uniprot id: A0A6I9LQH4
uniprot id: A0A6J0DV81
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CPSF4/YTH1 family.
messages: Component of the cleavage and polyadenylation specificity factor (CPSF) complex that play a key role in pre-mRNA 3'-end formation, recognizing the AAUAAA signal sequence and interacting with poly(A) polymerase and other factors to bring about cleavage and poly(A) addition. CPSF4 binds RNA polymers with a preference for poly(U).
messages: Component of the cleavage and polyadenylation specificity factor (CPSF) complex.
messages: Nucleus

230844:Gpr35
gene id: 230844:Gpr35
uniprot id: A0A6J0E741
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

230844:Eif3a
gene id: 230844:Eif3a
uniprot id: A0A6I9L7B5
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-3 subunit A family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is composed of 13 subunits: EIF3A, EIF3B, EIF3C, EIF3D, EIF3E, EIF3F, EIF3G, EIF3H, EIF3I, EIF3J, EIF3K, EIF3L and EIF3M. The eIF-3 complex appears to include 3 stable modules: module A is composed of EIF3A, EIF3B, EIF3G and EIF3I; module B is composed of EIF3F, EIF3H, and EIF3M; and module C is composed of EIF3C, EIF3D, EIF3E, EIF3L and EIF3K. EIF3C of module C binds EIF3B of module A and EIF3H of module B, thereby linking the three modules. EIF3J is a labile subunit that binds to the eIF-3 complex via EIF3B. The eIF-3 complex interacts with RPS6KB1 under conditions of nutrient depletion. Mitogenic stimulation leads to binding and activation of a complex composed of MTOR and RPTOR, leading to phosphorylation and release of RPS6KB1 and binding of EIF4B to eIF-3. Interacts with EIF4G1. Also interacts with KRT7 and PIWIL2.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Phosphorylated. Phosphorylation is enhanced upon serum stimulation.
messages: RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation, including cell cycling, differentiation and apoptosis, and uses different modes of RNA stem-loop binding to exert either translational activation or repression.

230844:Nectin4
gene id: 230844:Nectin4
uniprot id: A0A6I9LZS4
uniprot id: A0A6I9M5E4
names: Similarity
messages: Belongs to the nectin family.

230844:Selenbp1
gene id: 230844:Selenbp1
uniprot id: A0A6I9MIQ2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the selenium-binding protein family.
messages: Catalyzes the oxidation of methanethiol, an organosulfur compound known to be produced in substantial amounts by gut bacteria. Selenium-binding protein which may be involved in the sensing of reactive xenobiotics in the cytoplasm. May be involved in intra-Golgi protein transport.
messages: Interacts with USP33.
messages: Membrane
messages: Nucleus
messages: cytosol

230844:LOC102912858
gene id: 230844:LOC102912858
uniprot id: A0A6I9MGU4
names: Subcellular Location Annotation
messages: Cytoplasm

230844:Atp1b3
gene id: 230844:Atp1b3
uniprot id: A0A6I9L228
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the X(+)/potassium ATPases subunit beta family.
messages: Membrane
messages: This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane.

230844:Alk
gene id: 230844:Alk
uniprot id: A0A6I9LUR4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. Insulin receptor subfamily.
messages: Cell membrane

230844:Taar5
gene id: 230844:Taar5
uniprot id: A0A6I9LQK9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

230844:Kcnj5
gene id: 230844:Kcnj5
uniprot id: A0A6I9MCY7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family. KCNJ5 subfamily.
messages: Membrane

230844:Dlx4
gene id: 230844:Dlx4
uniprot id: A0A6I9KW03
names: Subcellular Location Annotation
messages: Nucleus

230844:Ift46
gene id: 230844:Ift46
uniprot id: A0A6I9MFX2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IFT46 family.
messages: cilium
messages: cilium basal body

230844:Serpinh1
gene id: 230844:Serpinh1
uniprot id: A0A6I9LNA8
names: Function
names: Similarity
messages: Belongs to the serpin family.
messages: Binds specifically to collagen. Could be involved as a chaperone in the biosynthetic pathway of collagen.

230844:Olfm2
gene id: 230844:Olfm2
uniprot id: A0A6I9LZF5
uniprot id: A0A6J0E324
names: Subcellular Location Annotation
messages: Secreted
messages: Synapse

230844:Pmvk
gene id: 230844:Pmvk
uniprot id: A0A6I9LBN9
names: Subcellular Location Annotation
messages: cytosol

230844:Dppa5
gene id: 230844:Dppa5
uniprot id: A0A6I9ME40
names: Similarity
messages: Belongs to the KHDC1 family.

230844:Gtf2h4
gene id: 230844:Gtf2h4
uniprot id: A0A6I9MEB6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TFB2 family.
messages: Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA.
messages: Nucleus

230844:Skor1
gene id: 230844:Skor1
uniprot id: A0A6I9KV77
names: Similarity
messages: Belongs to the SKI family.

230844:LOC102925694
gene id: 230844:LOC102925694
uniprot id: A0A6I9LE08
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calycin superfamily. Lipocalin family.
messages: Secreted

230844:LOC102920307
gene id: 230844:LOC102920307
uniprot id: A0A6I9MFE9
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

230844:LOC102924959
gene id: 230844:LOC102924959
uniprot id: A0A6I9LP19
uniprot id: A0A6J0DSN4
names: Similarity
messages: Belongs to the intermediate filament family.

230844:Ptdss2
gene id: 230844:Ptdss2
uniprot id: A0A6I9L639
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phosphatidyl serine synthase family.
messages: Catalyzes a base-exchange reaction in which the polar head group of phosphatidylethanolamine (PE) is replaced by L-serine.
messages: Endoplasmic reticulum membrane
messages: Membrane

230844:Ube2t
gene id: 230844:Ube2t
uniprot id: A0A6I9LGK3
uniprot id: A0A6J0DN15
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

230844:Cry1
gene id: 230844:Cry1
uniprot id: A0A6I9LN34
names: Cofactor
names: Similarity
messages: Belongs to the DNA photolyase class-1 family.
messages: Binds 1 FAD per subunit.

230844:B4galnt1
gene id: 230844:B4galnt1
uniprot id: A0A6I9L576
uniprot id: A0A6J0CXP3
uniprot id: A0A6J0CZ87
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family.
messages: Golgi apparatus membrane
messages: Membrane

230844:Gnal
gene id: 230844:Gnal
uniprot id: A0A6I9KSX1
uniprot id: A0A6I9KYL6
names: Similarity
messages: Belongs to the G-alpha family. G(s) subfamily.

230844:Scara5
gene id: 230844:Scara5
uniprot id: A0A6I9M1U2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SCARA5 family.
messages: Cell membrane
messages: Ferritin receptor that mediates non-transferrin-dependent delivery of iron. Mediates cellular uptake of ferritin-bound iron by stimulating ferritin endocytosis from the cell surface with consequent iron delivery within the cell. Delivery of iron to cells by ferritin is required for the development of specific cell types, suggesting the existence of cell type-specific mechanisms of iron traffic in organogenesis, which alternatively utilize transferrin or non-transferrin iron delivery pathways. Ferritin mediates iron uptake in capsule cells of the developing kidney. Binds preferrentially ferritin light chain (FTL) compared to heavy chain (FTH1).
messages: Homotrimer.
messages: Membrane

230844:Cr2
gene id: 230844:Cr2
uniprot id: A0A6I9M830
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

230844:Cldn2
gene id: 230844:Cldn2
uniprot id: A0A6J0CZI4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

230844:LOC102929043
gene id: 230844:LOC102929043
uniprot id: A0A6J0DZM5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDK2AP family.
messages: Nucleus

230844:Slu7
gene id: 230844:Slu7
uniprot id: A0A6J0E175
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associated with the spliceosome.
messages: Belongs to the SLU7 family.
messages: Involved in pre-mRNA splicing.
messages: Nucleus

230844:Krt35
gene id: 230844:Krt35
uniprot id: A0A6I9MC72
names: Similarity
messages: Belongs to the intermediate filament family.

230844:LOC102921916
gene id: 230844:LOC102921916
uniprot id: A0A6J0D2U5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome P450 family.
messages: Endoplasmic reticulum membrane

230844:LOC102907148
gene id: 230844:LOC102907148
uniprot id: A0A6I9LJU3
uniprot id: A0A6I9LV83
names: Similarity
messages: Belongs to the type-B carboxylesterase/lipase family.

230844:LOC102925582
gene id: 230844:LOC102925582
uniprot id: A0A6I9LA64
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Tln1
gene id: 230844:Tln1
uniprot id: A0A6I9M1N4
names: Subcellular Location Annotation
messages: cytoskeleton

230844:Aldh2
gene id: 230844:Aldh2
uniprot id: A0A6I9KZW9
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

230844:Btd
gene id: 230844:Btd
uniprot id: A0A6I9MC87
uniprot id: A0A6I9MG76
uniprot id: A0A6J0CR53
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. BTD/VNN family.

230844:LOC102909871
gene id: 230844:LOC102909871
uniprot id: A0A6I9MGA8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Il21
gene id: 230844:Il21
uniprot id: A0A6I9M2P5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IL-15/IL-21 family.
messages: Secreted

230844:Endog
gene id: 230844:Endog
uniprot id: A0A6I9LQW6
names: Similarity
messages: Belongs to the DNA/RNA non-specific endonuclease family.

230844:Nipa2
gene id: 230844:Nipa2
uniprot id: A0A6J0DDN3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NIPA family.
messages: Membrane

230844:LOC102924844
gene id: 230844:LOC102924844
uniprot id: A0A6I9MDQ3
names: Similarity
messages: Belongs to the FAM47 family.

230844:Ripply1
gene id: 230844:Ripply1
uniprot id: A0A6J0CYZ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ripply family.
messages: Nucleus

230844:Brox
gene id: 230844:Brox
uniprot id: A0A6I9M384
names: Similarity
messages: Belongs to the BROX family.

230844:Ssbp4
gene id: 230844:Ssbp4
uniprot id: A0A6I9LRZ1
uniprot id: A0A6J0E9D5
names: Subcellular Location Annotation
messages: Nucleus

230844:Ltv1
gene id: 230844:Ltv1
uniprot id: A0A6I9L505
names: Similarity
messages: Belongs to the LTV1 family.

230844:Bsph1
gene id: 230844:Bsph1
uniprot id: A0A6I9MPS0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

230844:Tmem33
gene id: 230844:Tmem33
uniprot id: A0A6I9L100
uniprot id: A0A6I9L875
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PER33/POM33 family.
messages: Membrane

230844:Elavl4
gene id: 230844:Elavl4
uniprot id: A0A6I9L612
uniprot id: A0A6I9L7B1
uniprot id: A0A6I9LEP0
uniprot id: A0A6I9LIR4
uniprot id: A0A6J0D8Q5
uniprot id: A0A6J0DA81
uniprot id: A0A6J0DB04
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRM elav family.
messages: Cytoplasm
messages: Perikaryon
messages: axon
messages: dendrite
messages: growth cone

230844:LOC102904854
gene id: 230844:LOC102904854
uniprot id: A0A6I9L8G8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Rin1
gene id: 230844:Rin1
uniprot id: A0A6I9LQQ4
names: Similarity
messages: Belongs to the RIN (Ras interaction/interference) family.

230844:LOC102905666
gene id: 230844:LOC102905666
uniprot id: A0A6I9MBU5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MHC class I family.
messages: Membrane

230844:LOC102910005
gene id: 230844:LOC102910005
uniprot id: A0A6J0CTL4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor T2R family.
messages: Membrane

230844:Tbx18
gene id: 230844:Tbx18
uniprot id: A0A6I9LHA6
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

230844:LOC102926604
gene id: 230844:LOC102926604
uniprot id: A0A6I9L9P8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:LOC102925720
gene id: 230844:LOC102925720
uniprot id: A0A6I9LXM0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Gspt1
gene id: 230844:Gspt1
uniprot id: A0A6I9LHM1
uniprot id: A0A6I9LSV0
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.

230844:LOC102906209
gene id: 230844:LOC102906209
uniprot id: A0A6I9LB45
uniprot id: A0A6I9LQ49
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GST superfamily. Pi family.
messages: Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles.
messages: Cytoplasm
messages: Homodimer.
messages: Mitochondrion
messages: Nucleus

230844:Ahcyl2
gene id: 230844:Ahcyl2
uniprot id: A0A6I9LHS6
uniprot id: A0A6J0DF14
uniprot id: A0A6J0DFG0
names: Cofactor
names: Similarity
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.

230844:LOC102928586
gene id: 230844:LOC102928586
uniprot id: A0A6I9MM92
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

230844:Mrpl40
gene id: 230844:Mrpl40
uniprot id: A0A6I9M8T8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mL40 family.
messages: Mitochondrion

230844:Rpl10
gene id: 230844:Rpl10
uniprot id: A0A6I9ME29
names: Similarity
messages: Belongs to the universal ribosomal protein uL16 family.

230844:LOC102912383
gene id: 230844:LOC102912383
uniprot id: A0A6I9LTG5
names: Function
names: Subunit
messages: In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins.
messages: Interacts with hair keratins.

230844:Slc2a2
gene id: 230844:Slc2a2
uniprot id: A0A6I9L0X3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. Glucose transporter subfamily.
messages: Cell membrane
messages: Membrane

230844:Marf1
gene id: 230844:Marf1
uniprot id: A0A6I9LJG0
uniprot id: A0A6I9LRS2
names: Subcellular Location Annotation
messages: Peroxisome

230844:Fto
gene id: 230844:Fto
uniprot id: A0A6I9LXN0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fto family.
messages: Cytoplasm
messages: Nucleus speckle

230844:Ing3
gene id: 230844:Ing3
uniprot id: A0A6I9M1G1
uniprot id: A0A6J0CJU4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ING family.
messages: Component of an histone acetyltransferase complex.
messages: Component of an histone acetyltransferase complex. Interacts with H3K4me3 and to a lesser extent with H3K4me2.
messages: Nucleus
messages: The PHD-type zinc finger mediates the binding to H3K4me3.

230844:LOC102904519
gene id: 230844:LOC102904519
uniprot id: A0A6I9KZY5
uniprot id: A0A6J0CZZ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TGF-beta family.
messages: Secreted

230844:Adamts8
gene id: 230844:Adamts8
uniprot id: A0A6I9LC81
names: Caution
names: Cofactor
names: Subcellular Location Annotation
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

230844:Glrx
gene id: 230844:Glrx
uniprot id: A0A6I9LXP7
names: Function
names: Similarity
messages: Belongs to the glutaredoxin family.
messages: Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins.

230844:Jrkl
gene id: 230844:Jrkl
uniprot id: A0A6I9M503
names: Subcellular Location Annotation
messages: Nucleus

230844:Sdhaf1
gene id: 230844:Sdhaf1
uniprot id: A0A6I9LTV1
names: Similarity
messages: Belongs to the complex I LYR family. SDHAF1 subfamily.

230844:Glipr1
gene id: 230844:Glipr1
uniprot id: A0A6J0D256
names: Similarity
messages: Belongs to the CRISP family.

230844:Fbp1
gene id: 230844:Fbp1
uniprot id: A0A6I9LF60
names: Similarity
messages: Belongs to the FBPase class 1 family.

230844:Jun
gene id: 230844:Jun
uniprot id: A0A6I9LAF3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bZIP family. Jun subfamily.
messages: Nucleus

230844:LOC102923694
gene id: 230844:LOC102923694
uniprot id: A0A6I9MEZ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome P450 family.
messages: Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Microsome membrane

230844:Rgma
gene id: 230844:Rgma
uniprot id: A0A6I9M618
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the repulsive guidance molecule (RGM) family.
messages: Cell membrane
messages: Membrane

230844:LOC102921627
gene id: 230844:LOC102921627
uniprot id: A0A6I9LHQ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Aste1
gene id: 230844:Aste1
uniprot id: A0A6J0DRU7
uniprot id: A0A6J0DS61
names: Similarity
messages: Belongs to the asteroid family.

230844:LOC102906642
gene id: 230844:LOC102906642
uniprot id: A0A6J0EAV9
names: Similarity
messages: Belongs to the arylamine N-acetyltransferase family.

230844:Nr4a2
gene id: 230844:Nr4a2
uniprot id: A0A6I9M518
uniprot id: A0A6J0CJD1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the nuclear hormone receptor family. NR4 subfamily.
messages: Cytoplasm
messages: Interacts with SFPQ, NCOR2, SIN3A and HADC1. The interaction with NCOR2 increases in the absence of PITX3. Interacts with PER2.
messages: Nucleus

230844:Uncx
gene id: 230844:Uncx
uniprot id: A0A6I9M0S6
names: Subcellular Location Annotation
messages: Nucleus

230844:Rnase11
gene id: 230844:Rnase11
uniprot id: A0A6I9MIS4
names: Similarity
messages: Belongs to the pancreatic ribonuclease family.

230844:Nanos1
gene id: 230844:Nanos1
uniprot id: A0A6J0DC83
names: Similarity
messages: Belongs to the nanos family.

230844:LOC102916442
gene id: 230844:LOC102916442
uniprot id: A0A6I9LUW1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

230844:Stard13
gene id: 230844:Stard13
uniprot id: A0A6J0E3R4
uniprot id: A0A6J0E749
names: Subcellular Location Annotation
messages: Cytoplasm

230844:Ccdc85c
gene id: 230844:Ccdc85c
uniprot id: A0A6J0E7S9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CCDC85 family.
messages: adherens junction

230844:Fundc1
gene id: 230844:Fundc1
uniprot id: A0A6I9LCU3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FUN14 family.
messages: Mitochondrion outer membrane

230844:LOC102920408
gene id: 230844:LOC102920408
uniprot id: A0A6I9L5K9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Ube2g1
gene id: 230844:Ube2g1
uniprot id: A0A6I9MA48
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

230844:Meig1
gene id: 230844:Meig1
uniprot id: A0A6J0DX33
names: Function
names: Similarity
messages: Belongs to the MEIG1 family.
messages: Essential for spermiogenesis.

230844:Ube2m
gene id: 230844:Ube2m
uniprot id: A0A6I9ME48
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

230844:Prop1
gene id: 230844:Prop1
uniprot id: A0A6I9LZI8
names: Function
names: Subcellular Location Annotation
messages: Nucleus
messages: Possibly involved in the ontogenesis of pituitary gonadotropes, as well as somatotropes, lactotropes and caudomedial thyrotropes.

230844:Sema4a
gene id: 230844:Sema4a
uniprot id: A0A6J0DBK5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

230844:Lgi2
gene id: 230844:Lgi2
uniprot id: A0A6J0D5U3
names: Subcellular Location Annotation
messages: Secreted

230844:Dock6
gene id: 230844:Dock6
uniprot id: A0A6I9LEN2
uniprot id: A0A6I9LUG4
uniprot id: A0A6J0DU93
names: Similarity
messages: Belongs to the DOCK family.

230844:LOC102912896
gene id: 230844:LOC102912896
uniprot id: A0A6I9LM85
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:LOC102915539
gene id: 230844:LOC102915539
uniprot id: A0A6I9MEX2
names: Similarity
messages: Belongs to the TENT family.

230844:Fam110b
gene id: 230844:Fam110b
uniprot id: A0A6J0CJW9
names: Similarity
messages: Belongs to the FAM110 family.

230844:Irgc
gene id: 230844:Irgc
uniprot id: A0A6I9MD72
names: Similarity
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. IRG family.

230844:LOC102905684
gene id: 230844:LOC102905684
uniprot id: A0A6I9LHZ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GST superfamily. Mu family.
messages: Cytoplasm

230844:Lipi
gene id: 230844:Lipi
uniprot id: A0A6I9LS98
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AB hydrolase superfamily. Lipase family.
messages: Secreted

230844:Rhbdl3
gene id: 230844:Rhbdl3
uniprot id: A0A6I9LE59
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S54 family.
messages: May be involved in regulated intramembrane proteolysis and the subsequent release of functional polypeptides from their membrane anchors.
messages: Membrane

230844:Slc27a2
gene id: 230844:Slc27a2
uniprot id: A0A6I9LMB2
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

230844:Smim8
gene id: 230844:Smim8
uniprot id: A0A6I9L2B1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SMIM8 family.
messages: Membrane

230844:Scnn1g
gene id: 230844:Scnn1g
uniprot id: A0A6I9LPM9
names: Subcellular Location Annotation
messages: Membrane

230844:LOC102917206
gene id: 230844:LOC102917206
uniprot id: A0A6J0CX22
names: Similarity
messages: Belongs to the universal ribosomal protein uL16 family.

230844:Rock2
gene id: 230844:Rock2
uniprot id: A0A6I9L3Y5
uniprot id: A0A6I9LC97
uniprot id: A0A6J0D635
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family.
messages: Cell membrane
messages: Membrane
messages: Nucleus
messages: centrosome

230844:Map7d1
gene id: 230844:Map7d1
uniprot id: A0A6I9LA97
uniprot id: A0A6I9LBV6
uniprot id: A0A6I9LJ12
uniprot id: A0A6I9LJ15
uniprot id: A0A6I9LK66
uniprot id: A0A6I9LP16
uniprot id: A0A6J0DEJ4
names: Similarity
messages: Belongs to the MAP7 family.

230844:LOC102914211
gene id: 230844:LOC102914211
uniprot id: A0A6I9MNJ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Membrane
messages: tight junction

230844:B4galt1
gene id: 230844:B4galt1
uniprot id: A0A6I9L2C7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 7 family.
messages: Golgi apparatus membrane
messages: Membrane
messages: Responsible for the synthesis of complex-type N-linked oligosaccharides in many glycoproteins as well as the carbohydrate moieties of glycolipids.

230844:Csn2
gene id: 230844:Csn2
uniprot id: A0A6I9M269
uniprot id: A0A6I9M7C7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the beta-casein family.
messages: Important role in determination of the surface properties of the casein micelles.
messages: Secreted

230844:Slit2
gene id: 230844:Slit2
uniprot id: A0A6I9L348
uniprot id: A0A6I9L3X0
uniprot id: A0A6I9LBA6
uniprot id: A0A6J0D4S6
uniprot id: A0A6J0D5W6
uniprot id: A0A6J0D6G1
uniprot id: A0A6J0D6Y6
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

230844:Sfmbt1
gene id: 230844:Sfmbt1
uniprot id: A0A6J0DKM7
uniprot id: A0A6J0DKS3
names: Subcellular Location Annotation
messages: Nucleus

230844:Sephs1
gene id: 230844:Sephs1
uniprot id: A0A6I9L0N0
names: Function
messages: Synthesizes selenophosphate from selenide and ATP.

230844:LOC102926834
gene id: 230844:LOC102926834
uniprot id: A0A6I9LPV0
names: Subcellular Location Annotation
messages: Nucleus

230844:Cep57l1
gene id: 230844:Cep57l1
uniprot id: A0A6I9LH62
names: Similarity
messages: Belongs to the translokin family.

230844:C1H11orf58
gene id: 230844:C1H11orf58
uniprot id: A0A6I9L7M2
names: Similarity
messages: Belongs to the SMAP family.

230844:Nmnat2
gene id: 230844:Nmnat2
uniprot id: A0A6I9LBK7
names: Similarity
messages: Belongs to the eukaryotic NMN adenylyltransferase family.

230844:Rnase9
gene id: 230844:Rnase9
uniprot id: A0A6I9MGH6
names: Similarity
messages: Belongs to the pancreatic ribonuclease family.

230844:LOC102906159
gene id: 230844:LOC102906159
uniprot id: A0A6I9M0B5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:LOC102920750
gene id: 230844:LOC102920750
uniprot id: A0A6I9LXK2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Atp5f1b
gene id: 230844:Atp5f1b
uniprot id: A0A6I9LS45
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

230844:LOC102916719
gene id: 230844:LOC102916719
uniprot id: A0A6I9MQ45
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:LOC102912823
gene id: 230844:LOC102912823
uniprot id: A0A6I9M2S1
names: Function
names: Similarity
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.
messages: FABPs are thought to play a role in the intracellular transport of long-chain fatty acids and their acyl-CoA esters. FABP2 is probably involved in triglyceride-rich lipoprotein synthesis. Binds saturated long-chain fatty acids with a high affinity, but binds with a lower affinity to unsaturated long-chain fatty acids. FABP2 may also help maintain energy homeostasis by functioning as a lipid sensor.

230844:Arsg
gene id: 230844:Arsg
uniprot id: A0A6I9L274
names: Similarity
messages: Belongs to the sulfatase family.

230844:LOC102917662
gene id: 230844:LOC102917662
uniprot id: A0A6J0DWB5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:LOC102928161
gene id: 230844:LOC102928161
uniprot id: A0A6I9M974
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Adamts1
gene id: 230844:Adamts1
uniprot id: A0A6I9LPV7
names: Caution
names: Cofactor
names: Subcellular Location Annotation
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

230844:LOC102926674
gene id: 230844:LOC102926674
uniprot id: A0A6I9KWD2
uniprot id: A0A6I9L688
names: Similarity
names: Subunit
messages: Belongs to the peptidase M18 family.
messages: Tetrahedron-shaped homododecamer built from six homodimers.

230844:LOC102918404
gene id: 230844:LOC102918404
uniprot id: A0A6I9LRL8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Crybg3
gene id: 230844:Crybg3
uniprot id: A0A6I9LEZ5
names: Similarity
messages: Belongs to the beta/gamma-crystallin family.

230844:Lcn2
gene id: 230844:Lcn2
uniprot id: A0A6I9LWL3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calycin superfamily. Lipocalin family.
messages: Secreted

230844:LOC102922350
gene id: 230844:LOC102922350
uniprot id: A0A6I9ML34
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Dpt
gene id: 230844:Dpt
uniprot id: A0A6I9L8I3
names: Similarity
messages: Belongs to the dermatopontin family.

230844:LOC102910060
gene id: 230844:LOC102910060
uniprot id: A0A6I9LND8
names: Similarity
messages: Belongs to the cytochrome P450 family.

230844:Map4k5
gene id: 230844:Map4k5
uniprot id: A0A6I9LMV2
uniprot id: A0A6I9LVA2
names: Function
names: Similarity
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.
messages: May play a role in the response to environmental stress. Appears to act upstream of the JUN N-terminal pathway.

230844:LOC107402806
gene id: 230844:LOC107402806
uniprot id: A0A6J0ED16
names: Subcellular Location Annotation
messages: Nucleus

230844:LOC102918729
gene id: 230844:LOC102918729
uniprot id: A0A6I9M7M1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:LOC102920705
gene id: 230844:LOC102920705
uniprot id: A0A6I9LI94
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

230844:Wdr55
gene id: 230844:Wdr55
uniprot id: A0A6I9M9Z8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat WDR55 family.
messages: Nucleolar protein that acts as a modulator of rRNA synthesis. Plays a central role during organogenesis.
messages: nucleolus

230844:Slc25a31
gene id: 230844:Slc25a31
uniprot id: A0A6I9LSE0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Catalyzes the exchange of ADP and ATP across the membrane.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Monomer.

230844:Tmlhe
gene id: 230844:Tmlhe
uniprot id: A0A6J0D0Q6
names: Similarity
messages: Belongs to the gamma-BBH/TMLD family.

230844:LOC102904682
gene id: 230844:LOC102904682
uniprot id: A0A6I9LYL3
names: Similarity
messages: Belongs to the type-B carboxylesterase/lipase family.

230844:Ppil4
gene id: 230844:Ppil4
uniprot id: A0A6I9LTU5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cyclophilin-type PPIase family. PPIL4 subfamily.
messages: Nucleus
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

230844:Ucp3
gene id: 230844:Ucp3
uniprot id: A0A6J0DM83
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

230844:Bnip3
gene id: 230844:Bnip3
uniprot id: A0A6I9LSQ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NIP3 family.
messages: Membrane

230844:Arsk
gene id: 230844:Arsk
uniprot id: A0A6I9LME3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfatase family.
messages: Lysosome

230844:Eml4
gene id: 230844:Eml4
uniprot id: A0A6I9M6H1
uniprot id: A0A6J0E7H1
uniprot id: A0A6J0E9A5
uniprot id: A0A6J0EB86
uniprot id: A0A6J0EDG7
uniprot id: A0A6J0EEZ9
names: Similarity
messages: Belongs to the WD repeat EMAP family.

230844:LOC102910554
gene id: 230844:LOC102910554
uniprot id: A0A6I9LKE3
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

230844:Xrcc1
gene id: 230844:Xrcc1
uniprot id: A0A6I9M647
uniprot id: A0A6I9MD62
names: Subcellular Location Annotation
messages: Nucleus

230844:LOC107400216
gene id: 230844:LOC107400216
uniprot id: A0A6J0CXQ4
names: Similarity
names: Subunit
messages: Belongs to the histone H3 family.
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

230844:Camk2b
gene id: 230844:Camk2b
uniprot id: A0A6I9KXX0
uniprot id: A0A6I9L4J3
uniprot id: A0A6I9L4W1
uniprot id: A0A6I9L841
names: Similarity
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. CaMK subfamily.

230844:Ccn1
gene id: 230844:Ccn1
uniprot id: A0A6I9LYT5
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CCN family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

230844:Nfil3
gene id: 230844:Nfil3
uniprot id: A0A6J0D8G8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a transcriptional regulator that recognizes and binds to the sequence 5'-[GA]TTA[CT]GTAA[CT]-3', a sequence present in many cellular and viral promoters. Represses transcription from promoters with activating transcription factor (ATF) sites. Represses promoter activity in osteoblasts. Represses transcriptional activity of PER1. Represses transcriptional activity of PER2 via the B-site on the promoter. Activates transcription from the interleukin-3 promoter in T-cells. Competes for the same consensus-binding site with PAR DNA-binding factors (DBP, HLF and TEF). Component of the circadian clock that acts as a negative regulator for the circadian expression of PER2 oscillation in the cell-autonomous core clock. Protects pro-B cells from programmed cell death.
messages: Belongs to the bZIP family. NFIL3 subfamily.
messages: Homodimer. Binds DNA as a dimer.
messages: Nucleus

230844:Hars1
gene id: 230844:Hars1
uniprot id: A0A6I9MGJ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm

230844:LOC102904209
gene id: 230844:LOC102904209
uniprot id: A0A6J0D592
names: Function
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein P1/P2 family.
messages: Plays an important role in the elongation step of protein synthesis.

230844:Ush2a
gene id: 230844:Ush2a
uniprot id: A0A6I9KVX8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

230844:LOC102915952
gene id: 230844:LOC102915952
uniprot id: A0A6I9MGU3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Pitx1
gene id: 230844:Pitx1
uniprot id: A0A6I9L485
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the paired homeobox family. Bicoid subfamily.
messages: Nucleus

230844:Insl6
gene id: 230844:Insl6
uniprot id: A0A6I9M7K5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the insulin family.
messages: May have a role in sperm development and fertilization.
messages: Secreted

230844:Hexa
gene id: 230844:Hexa
uniprot id: A0A6I9L1P4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 20 family.
messages: Lysosome

230844:LOC102918223
gene id: 230844:LOC102918223
uniprot id: A0A6I9MFX9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Msh5
gene id: 230844:Msh5
uniprot id: A0A6J0CNX5
uniprot id: A0A6J0CRK6
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.

230844:Panx3
gene id: 230844:Panx3
uniprot id: A0A6I9MNZ6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pannexin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Structural component of the gap junctions and the hemichannels.
messages: gap junction

230844:Spata5l1
gene id: 230844:Spata5l1
uniprot id: A0A6J0DK79
names: Similarity
messages: Belongs to the AAA ATPase family.

230844:Gpr3
gene id: 230844:Gpr3
uniprot id: A0A6I9MRF5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Dynlt2
gene id: 230844:Dynlt2
uniprot id: A0A6I9L3K2
names: Similarity
messages: Belongs to the dynein light chain Tctex-type family.

230844:Nifk
gene id: 230844:Nifk
uniprot id: A0A6I9M363
uniprot id: A0A6I9MJV9
names: Subcellular Location Annotation
messages: nucleolus

230844:Abca3
gene id: 230844:Abca3
uniprot id: A0A6J0DED3
names: Subcellular Location Annotation
messages: Membrane

230844:Cdc42se1
gene id: 230844:Cdc42se1
uniprot id: A0A6J0DN80
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CDC42SE/SPEC family.
messages: Cell membrane
messages: Interacts with CDC42 (in GTP-bound form). Interacts weakly with RAC1 and not at all with RHOA.
messages: Membrane
messages: Probably involved in the organization of the actin cytoskeleton by acting downstream of CDC42, inducing actin filament assembly. Alters CDC42-induced cell shape changes. In activated T-cells, may play a role in CDC42-mediated F-actin accumulation at the immunological synapse. May play a role in early contractile events in phagocytosis in macrophages.
messages: cytoskeleton

230844:LOC102913392
gene id: 230844:LOC102913392
uniprot id: A0A6I9LG98
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

230844:LOC102909726
gene id: 230844:LOC102909726
uniprot id: A0A6I9LLD0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPATA31 family.
messages: Membrane

230844:Plin3
gene id: 230844:Plin3
uniprot id: A0A6J0DN96
names: Similarity
messages: Belongs to the perilipin family.

230844:Adamts14
gene id: 230844:Adamts14
uniprot id: A0A6I9KX33
names: Caution
names: Cofactor
names: Subcellular Location Annotation
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

230844:Ddah1
gene id: 230844:Ddah1
uniprot id: A0A6I9LJ00
names: Function
names: Similarity
messages: Belongs to the DDAH family.
messages: Hydrolyzes N(G),N(G)-dimethyl-L-arginine (ADMA) and N(G)-monomethyl-L-arginine (MMA) which act as inhibitors of NOS. Has therefore a role in the regulation of nitric oxide generation.

230844:LOC102922129
gene id: 230844:LOC102922129
uniprot id: A0A6I9M109
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

230844:LOC102908470
gene id: 230844:LOC102908470
uniprot id: A0A6I9LEX8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Supt16h
gene id: 230844:Supt16h
uniprot id: A0A6I9MFZ3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase M24 family. SPT16 subfamily.
messages: Chromosome
messages: Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment of the nucleosome following the passage of RNA polymerase II.
messages: Component of the FACT complex.
messages: Nucleus

230844:Wnt6
gene id: 230844:Wnt6
uniprot id: A0A6I9KWB1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

230844:Cplx3
gene id: 230844:Cplx3
uniprot id: A0A6I9L4P5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complexin/synaphin family.
messages: Synapse

230844:Bhmt
gene id: 230844:Bhmt
uniprot id: A0A6I9LDK7
names: Cofactor
names: Function
names: Subunit
messages: Binds 1 zinc ion per subunit.
messages: Homotetramer.
messages: Involved in the regulation of homocysteine metabolism.

230844:Psen1
gene id: 230844:Psen1
uniprot id: A0A6J0CW18
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase A22A family.
messages: Cytoplasmic granule
messages: Early endosome membrane
messages: Endoplasmic reticulum membrane
messages: Endosome membrane
messages: Golgi apparatus membrane
messages: Homodimer.
messages: Membrane
messages: Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors.
messages: Synapse
messages: The PAL motif is required for normal active site conformation.
messages: axon
messages: neuron projection

230844:Guca2a
gene id: 230844:Guca2a
uniprot id: A0A6I9M265
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylin family.
messages: Secreted

230844:Rab3il1
gene id: 230844:Rab3il1
uniprot id: A0A6J0CHS6
uniprot id: A0A6J0CKE1
names: Similarity
messages: Belongs to the SEC2 family.

230844:Amdhd2
gene id: 230844:Amdhd2
uniprot id: A0A6I9L874
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. NagA family.
messages: Binds 1 divalent metal cation per subunit.
messages: Hydrolyzes the N-glycolyl group from N-glycolylglucosamine 6-phosphate (GlcNGc-6-P) in the N-glycolylneuraminic acid (Neu5Gc) degradation pathway.

230844:Tnmd
gene id: 230844:Tnmd
uniprot id: A0A6I9LXG7
names: Similarity
messages: Belongs to the chondromodulin-1 family.

230844:Nkx1-1
gene id: 230844:Nkx1-1
uniprot id: A0A6I9L877
names: Subcellular Location Annotation
messages: Nucleus

230844:Smim14
gene id: 230844:Smim14
uniprot id: A0A6I9L0Y6
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane

230844:LOC102905457
gene id: 230844:LOC102905457
uniprot id: A0A6I9MG07
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Nap1l3
gene id: 230844:Nap1l3
uniprot id: A0A6I9LW15
names: Similarity
messages: Belongs to the nucleosome assembly protein (NAP) family.

230844:Ids
gene id: 230844:Ids
uniprot id: A0A6I9M6Q0
names: Similarity
messages: Belongs to the sulfatase family.

230844:Creld1
gene id: 230844:Creld1
uniprot id: A0A6I9M9C2
names: Caution
names: Similarity
messages: Belongs to the CRELD family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

230844:Cxcl12
gene id: 230844:Cxcl12
uniprot id: A0A6I9MBR2
uniprot id: A0A6I9MJ44
names: Similarity
messages: Belongs to the intercrine alpha (chemokine CxC) family.

230844:Mepce
gene id: 230844:Mepce
uniprot id: A0A6I9L3Z4
names: Similarity
messages: Belongs to the methyltransferase superfamily.

230844:Snx1
gene id: 230844:Snx1
uniprot id: A0A6I9L8V9
uniprot id: A0A6J0DEU7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sorting nexin family.
messages: Early endosome membrane
messages: Endosome membrane
messages: Membrane
messages: lamellipodium
messages: trans-Golgi network membrane

230844:Eif4ebp2
gene id: 230844:Eif4ebp2
uniprot id: A0A6I9L7G5
names: Similarity
messages: Belongs to the eIF4E-binding protein family.

230844:C1H11orf68
gene id: 230844:C1H11orf68
uniprot id: A0A6J0DI85
names: Similarity
messages: Belongs to the UPF0696 family.

230844:Tspan15
gene id: 230844:Tspan15
uniprot id: A0A6I9L7H6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

230844:LOC102912017
gene id: 230844:LOC102912017
uniprot id: A0A6I9LF70
uniprot id: A0A6I9LJC4
names: Similarity
messages: Belongs to the fl(2)d family.

230844:Abraxas2
gene id: 230844:Abraxas2
uniprot id: A0A6I9L5L3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAM175 family. Abro1 subfamily.
messages: Nucleus
messages: spindle pole

230844:LOC102906102
gene id: 230844:LOC102906102
uniprot id: A0A6I9LLM4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

230844:LOC102924096
gene id: 230844:LOC102924096
uniprot id: A0A6I9M3U7
names: Subcellular Location Annotation
messages: Membrane

230844:Ncr3
gene id: 230844:Ncr3
uniprot id: A0A6I9M2T9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the natural cytotoxicity receptor (NCR) family.
messages: Cell membrane
messages: Homodimer in the unliganted form. Interacts with CD3Z. Interacts with and is activated by binding to NCR3LG1. Interacts with and is activated by binding to BAG6.
messages: Membrane

230844:LOC102910821
gene id: 230844:LOC102910821
uniprot id: A0A6I9M5C5
names: Cofactor
names: PTM
names: Similarity
messages: Belongs to the copper/topaquinone oxidase family.
messages: Contains 1 topaquinone per subunit.
messages: Topaquinone (TPQ) is generated by copper-dependent autoxidation of a specific tyrosyl residue.

230844:Apoc2
gene id: 230844:Apoc2
uniprot id: A0A6I9M9M9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the apolipoprotein C2 family.
messages: Component of chylomicrons, very low-density lipoproteins (VLDL), low-density lipoproteins (LDL), and high-density lipoproteins (HDL) in plasma. Plays an important role in lipoprotein metabolism as an activator of lipoprotein lipase.
messages: Secreted

230844:LOC102904599
gene id: 230844:LOC102904599
uniprot id: A0A6I9LWG5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

230844:Man1b1
gene id: 230844:Man1b1
uniprot id: A0A6I9LRB9
names: Similarity
messages: Belongs to the glycosyl hydrolase 47 family.

230844:Ak6
gene id: 230844:Ak6
uniprot id: A0A6I9LQM1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family. AK6 subfamily.
messages: Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates. May have a role in nuclear energy homeostasis. Has also ATPase activity. May be involved in regulation of Cajal body (CB) formation.
messages: Cajal body
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer and homodimer. Interacts with COIL (via C-terminus).
messages: nucleoplasm

230844:Tinag
gene id: 230844:Tinag
uniprot id: A0A6I9L9S0
names: Similarity
messages: Belongs to the peptidase C1 family.

230844:LOC102925098
gene id: 230844:LOC102925098
uniprot id: A0A6I9M412
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Sparc
gene id: 230844:Sparc
uniprot id: A0A6I9LJ96
uniprot id: A0A6I9LUP2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Appears to regulate cell growth through interactions with the extracellular matrix and cytokines. Binds calcium and copper, several types of collagen, albumin, thrombospondin, PDGF and cell membranes. There are two calcium binding sites; an acidic domain that binds 5 to 8 Ca(2+) with a low affinity and an EF-hand loop that binds a Ca(2+) ion with a high affinity.
messages: Belongs to the SPARC family.
messages: Membrane
messages: basement membrane

230844:Chit1
gene id: 230844:Chit1
uniprot id: A0A6I9LNZ0
names: Similarity
messages: Belongs to the glycosyl hydrolase 18 family. Chitinase class II subfamily.

230844:LOC102909475
gene id: 230844:LOC102909475
uniprot id: A0A6I9MNR7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Pts
gene id: 230844:Pts
uniprot id: A0A6I9L6R0
uniprot id: A0A6J0CJD7
names: Similarity
messages: Belongs to the PTPS family.

230844:Casp14
gene id: 230844:Casp14
uniprot id: A0A6I9MCU0
names: Similarity
messages: Belongs to the peptidase C14A family.

230844:Slc12a5
gene id: 230844:Slc12a5
uniprot id: A0A6I9KUD6
uniprot id: A0A6I9L0G6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC12A transporter family.
messages: Membrane

230844:Cluh
gene id: 230844:Cluh
uniprot id: A0A6I9LDT6
uniprot id: A0A6I9LHW3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CLU family.
messages: Cytoplasm
messages: Cytoplasmic granule
messages: mRNA-binding protein involved in proper cytoplasmic distribution of mitochondria. Specifically binds mRNAs of nuclear-encoded mitochondrial proteins in the cytoplasm and regulates transport or translation of these transcripts close to mitochondria, playing a role in mitochondrial biogenesis.

230844:Mtg2
gene id: 230844:Mtg2
uniprot id: A0A6I9L313
names: Similarity
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.

230844:Fxyd2
gene id: 230844:Fxyd2
uniprot id: A0A6J0EBF0
uniprot id: A0A6J0ECY7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FXYD family.
messages: May be involved in forming the receptor site for cardiac glycoside binding or may modulate the transport function of the sodium ATPase.
messages: Membrane
messages: Regulatory subunit of the sodium/potassium-transporting ATPase which is composed of a catalytic alpha subunit, an auxiliary non-catalytic beta subunit and an additional regulatory subunit.

230844:Ints14
gene id: 230844:Ints14
uniprot id: A0A6I9LM62
uniprot id: A0A6J0DEX8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the INTS14 family.
messages: Nucleus
messages: Probable component of the Integrator (INT) complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'-box-dependent processing.

230844:LOC102905332
gene id: 230844:LOC102905332
uniprot id: A0A6I9L852
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2A family.
messages: Chromosome
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

230844:Hmga2
gene id: 230844:Hmga2
uniprot id: A0A6J0D2D3
names: Similarity
messages: Belongs to the HMGA family.

230844:LOC102921997
gene id: 230844:LOC102921997
uniprot id: A0A6J0EFA2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 14 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex.
messages: Nucleus

230844:Letmd1
gene id: 230844:Letmd1
uniprot id: A0A6I9LFJ3
uniprot id: A0A6J0DM77
names: Subcellular Location Annotation
messages: Membrane
messages: Mitochondrion inner membrane

230844:Rimklb
gene id: 230844:Rimklb
uniprot id: A0A6I9M106
names: Similarity
messages: Belongs to the RimK family.

230844:Rnf146
gene id: 230844:Rnf146
uniprot id: A0A6J0EDV4
names: Domain
names: Function
names: PTM
names: Subcellular Location Annotation
names: Subunit
messages: Can form homooligomers. Interacts with PARsylated AXIN1, AXIN2, BLZF1, CASC3, H1-2, IPO7, LIG3, NCL, PARP1, XRCC1, XRCC5 and XRCC6. Interacts with DDB1, DHX15, IQGAP1, LRPPRC, PARP2, PRKDC, RUVBL2, TNKS1 and TNKS2. Binding often leads to interactor ubiquitination, in the presence of the appropriate E1 and E2 enzymes, and proteasomal degradation.
messages: E3 ubiquitin-protein ligase that specifically binds poly-ADP-ribosylated proteins and mediates their ubiquitination and subsequent degradation.
messages: The WWE domain mediates non-covalent poly(ADP-ribose)-binding.
messages: Ubiquitinated; autoubiquitinated.
messages: cytosol

230844:Sptssb
gene id: 230844:Sptssb
uniprot id: A0A6J0CSW0
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

230844:Mfsd9
gene id: 230844:Mfsd9
uniprot id: A0A6I9LSK2
names: Subcellular Location Annotation
messages: Membrane

230844:Exoc6
gene id: 230844:Exoc6
uniprot id: A0A6I9LG57
names: Function
names: Similarity
messages: Belongs to the SEC15 family.
messages: Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.

230844:LOC102914612
gene id: 230844:LOC102914612
uniprot id: A0A6I9MEP2
names: Similarity
messages: Belongs to the kindlin family.

230844:Fnip2
gene id: 230844:Fnip2
uniprot id: A0A6I9LLA3
uniprot id: A0A6J0DGY8
uniprot id: A0A6J0DJM3
uniprot id: A0A6J0DQA5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FNIP family.
messages: Lysosome membrane
messages: Membrane

230844:Tac1
gene id: 230844:Tac1
uniprot id: A0A6I9LYZ9
uniprot id: A0A6I9M3G4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tachykinin family.
messages: Secreted
messages: Tachykinins are active peptides which excite neurons, evoke behavioral responses, are potent vasodilators and secretagogues, and contract (directly or indirectly) many smooth muscles.

230844:LOC102915763
gene id: 230844:LOC102915763
uniprot id: A0A6I9MCI2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Pomgnt2
gene id: 230844:Pomgnt2
uniprot id: A0A6I9LVJ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 61 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

230844:Ankrd13c
gene id: 230844:Ankrd13c
uniprot id: A0A6I9L1H7
names: Subcellular Location Annotation
messages: Membrane

230844:LOC102913558
gene id: 230844:LOC102913558
uniprot id: A0A6I9LYH1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2A family.
messages: Chromosome
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

230844:Znf592
gene id: 230844:Znf592
uniprot id: A0A6I9L110
names: Function
names: Subcellular Location Annotation
messages: May be involved in transcriptional regulation.
messages: Nucleus

230844:Cx3cr1
gene id: 230844:Cx3cr1
uniprot id: A0A6I9M4V1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Found in a ternary complex with CX3CL1 and ITGAV:ITGB3 or ITGA4:ITGB1.
messages: Membrane

230844:Smoc1
gene id: 230844:Smoc1
uniprot id: A0A6I9KY29
uniprot id: A0A6J0CXS6
uniprot id: A0A6J0D1A5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

230844:Ms4a1
gene id: 230844:Ms4a1
uniprot id: A0A6I9MJX2
names: Similarity
messages: Belongs to the MS4A family.

230844:Slc10a4
gene id: 230844:Slc10a4
uniprot id: A0A6I9LJF7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bile acid:sodium symporter (BASS) (TC 2.A.28) family.
messages: Membrane

230844:LOC102909418
gene id: 230844:LOC102909418
uniprot id: A0A6I9M1I4
names: Similarity
messages: Belongs to the aldo/keto reductase family.

230844:Ppp1r13b
gene id: 230844:Ppp1r13b
uniprot id: A0A6I9LPY4
names: Subcellular Location Annotation
messages: Nucleus

230844:Synpr
gene id: 230844:Synpr
uniprot id: A0A6I9L1U2
uniprot id: A0A6I9L955
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptophysin/synaptobrevin family.
messages: Membrane

230844:Slc7a4
gene id: 230844:Slc7a4
uniprot id: A0A6J0DJN2
names: Subcellular Location Annotation
messages: Membrane

230844:LOC102923293
gene id: 230844:LOC102923293
uniprot id: A0A6I9MMC6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

230844:Ccr4
gene id: 230844:Ccr4
uniprot id: A0A6I9L1Q4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

230844:LOC102924224
gene id: 230844:LOC102924224
uniprot id: A0A6I9MHU7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:LOC102913229
gene id: 230844:LOC102913229
uniprot id: A0A6I9M586
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Xkrx
gene id: 230844:Xkrx
uniprot id: A0A6I9M2J1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the XK family.
messages: Membrane

230844:Sorcs1
gene id: 230844:Sorcs1
uniprot id: A0A6I9LGI1
uniprot id: A0A6I9LIC2
uniprot id: A0A6I9LQN9
uniprot id: A0A6I9LRQ5
uniprot id: A0A6I9LW97
names: Similarity
messages: Belongs to the VPS10-related sortilin family. SORCS subfamily.

230844:LOC102919559
gene id: 230844:LOC102919559
uniprot id: A0A6I9L1I4
names: Similarity
messages: Belongs to the PRR23 family.

230844:Keap1
gene id: 230844:Keap1
uniprot id: A0A6I9LYR0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KEAP1 family.
messages: Cytoplasm
messages: Nucleus

230844:Tnfrsf4
gene id: 230844:Tnfrsf4
uniprot id: A0A6I9MDW5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

230844:Itga2
gene id: 230844:Itga2
uniprot id: A0A6I9LIX0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin alpha chain family.
messages: Membrane

230844:Tas2r40
gene id: 230844:Tas2r40
uniprot id: A0A6I9MN47
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor T2R family.
messages: Membrane

230844:Gpc1
gene id: 230844:Gpc1
uniprot id: A0A6I9M8Z0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glypican family.
messages: Cell membrane
messages: Cell surface proteoglycan.

230844:LOC102906923
gene id: 230844:LOC102906923
uniprot id: A0A6I9MPX5
names: Similarity
messages: Belongs to the type-B carboxylesterase/lipase family.

230844:Ccn4
gene id: 230844:Ccn4
uniprot id: A0A6I9LCB9
uniprot id: A0A6J0DH74
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CCN family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

230844:LOC102910096
gene id: 230844:LOC102910096
uniprot id: A0A6I9MBY6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily.
messages: Membrane

230844:Ttc21b
gene id: 230844:Ttc21b
uniprot id: A0A6I9LHC7
uniprot id: A0A6J0D8T7
names: Similarity
messages: Belongs to the TTC21 family.

230844:Rtca
gene id: 230844:Rtca
uniprot id: A0A6I9LES9
uniprot id: A0A6J0D8T3
names: Function
names: Similarity
messages: Belongs to the RNA 3'-terminal cyclase family. Type 1 subfamily.
messages: Catalyzes the conversion of 3'-phosphate to a 2',3'-cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps: (A) adenylation of the enzyme by ATP; (B) transfer of adenylate to an RNA-N3'P to produce RNA-N3'PP5'A; (C) and attack of the adjacent 2'-hydroxyl on the 3'-phosphorus in the diester linkage to produce the cyclic end product. The biological role of this enzyme is unknown but it is likely to function in some aspects of cellular RNA processing.

230844:Cacnb4
gene id: 230844:Cacnb4
uniprot id: A0A6I9L016
uniprot id: A0A6I9L7A3
uniprot id: A0A6I9LAX9
names: Similarity
messages: Belongs to the calcium channel beta subunit family.

230844:LOC102912338
gene id: 230844:LOC102912338
uniprot id: A0A6I9MCH7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Cd36
gene id: 230844:Cd36
uniprot id: A0A6I9L0I2
names: Similarity
messages: Belongs to the CD36 family.

230844:Mnx1
gene id: 230844:Mnx1
uniprot id: A0A6I9MME6
names: Subcellular Location Annotation
messages: Nucleus

230844:LOC102923679
gene id: 230844:LOC102923679
uniprot id: A0A6I9MA78
names: Subcellular Location Annotation
messages: Membrane

230844:Yae1
gene id: 230844:Yae1
uniprot id: A0A6I9LJ61
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

230844:LOC102904671
gene id: 230844:LOC102904671
uniprot id: A0A6J0DSS0
names: Similarity
messages: Belongs to the universal ribosomal protein uS4 family.

230844:Tmem132a
gene id: 230844:Tmem132a
uniprot id: A0A6I9M7J8
uniprot id: A0A6I9MBQ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM132 family.
messages: Membrane

230844:LOC102905429
gene id: 230844:LOC102905429
uniprot id: A0A6I9LZE9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone H1/H5 family.
messages: Nucleus

230844:Myo9a
gene id: 230844:Myo9a
uniprot id: A0A6J0DTD1
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.

230844:Dclre1c
gene id: 230844:Dclre1c
uniprot id: A0A6J0E3Q7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA repair metallo-beta-lactamase (DRMBL) family.
messages: Nucleus

230844:Slc6a12
gene id: 230844:Slc6a12
uniprot id: A0A6I9M234
uniprot id: A0A6J0EI76
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Basolateral cell membrane
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. SLC6A12 subfamily.
messages: Cell membrane
messages: Interacts with LIN7C.
messages: Lateral cell membrane
messages: Membrane

230844:Trabd2b
gene id: 230844:Trabd2b
uniprot id: A0A6I9M2X7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TIKI family.
messages: Cell membrane
messages: Divalent metal cations. Mn(2+) or Co(2+).
messages: Membrane
messages: Metalloprotease that acts as a negative regulator of the Wnt signaling pathway by mediating the cleavage of the N-terminal residues of a subset of Wnt proteins. Following cleavage, Wnt proteins become oxidized and form large disulfide-bond oligomers, leading to their inactivation.

230844:Fxr1
gene id: 230844:Fxr1
uniprot id: A0A6I9KU35
uniprot id: A0A6I9KUL5
uniprot id: A0A6I9L0S2
uniprot id: A0A6J0DL93
uniprot id: A0A6J0DSD7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FMR1 family.
messages: Cytoplasmic ribonucleoprotein granule
messages: Postsynapse

230844:Nptx1
gene id: 230844:Nptx1
uniprot id: A0A6I9LPG3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

230844:Gipc1
gene id: 230844:Gipc1
uniprot id: A0A6I9MA86
names: Similarity
messages: Belongs to the GIPC family.

230844:LOC102917904
gene id: 230844:LOC102917904
uniprot id: A0A6I9M4J6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

230844:Nploc4
gene id: 230844:Nploc4
uniprot id: A0A6I9M169
names: Similarity
messages: Belongs to the NPL4 family.

230844:LOC102908793
gene id: 230844:LOC102908793
uniprot id: A0A6I9LUF8
names: Similarity
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. IRG family.

230844:LOC102906773
gene id: 230844:LOC102906773
uniprot id: A0A6I9ME56
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Ap2m1
gene id: 230844:Ap2m1
uniprot id: A0A6I9LPJ2
uniprot id: A0A6I9LZZ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adaptor complexes medium subunit family.
messages: Cell membrane
messages: Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold but is itself unable to bind directly to membrane components. Clathrin-associated adaptor protein (AP) complexes which can bind directly to both the clathrin lattice and to the lipid and protein components of membranes are considered to be the major clathrin adaptors contributing the CCV formation. AP-2 also serves as a cargo receptor to selectively sort the membrane proteins involved in receptor-mediated endocytosis. AP-2 seems to play a role in the recycling of synaptic vesicle membranes from the presynaptic surface. AP-2 recognizes Y-X-X-[FILMV] (Y-X-X-Phi) and [ED]-X-X-X-L-[LI] endocytosis signal motifs within the cytosolic tails of transmembrane cargo molecules.
messages: coated pit

230844:LOC102909712
gene id: 230844:LOC102909712
uniprot id: A0A6I9LM76
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Il36rn
gene id: 230844:Il36rn
uniprot id: A0A6I9LM97
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IL-1 family.
messages: Secreted

230844:LOC102905531
gene id: 230844:LOC102905531
uniprot id: A0A6J0CIW4
names: Similarity
messages: Belongs to the XLR/SYCP3 family.

230844:LOC107399387
gene id: 230844:LOC107399387
uniprot id: A0A6J0CG69
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the somatotropin/prolactin family.
messages: Secreted

230844:Znf496
gene id: 230844:Znf496
uniprot id: A0A6I9M7H7
uniprot id: A0A6I9MN97
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the krueppel C2H2-type zinc-finger protein family.
messages: Nucleus

230844:Calcrl
gene id: 230844:Calcrl
uniprot id: A0A6I9LXC0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 2 family.
messages: Cell membrane
messages: Heterodimer of CALCRL and RAMP1, RAMP2 or RAMP3.
messages: Membrane
messages: Receptor for calcitonin-gene-related peptide (CGRP) together with RAMP1 and receptor for adrenomedullin together with RAMP2 or RAMP3. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase.

230844:Arl2
gene id: 230844:Arl2
uniprot id: A0A6I9LD70
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Arf family.
messages: centrosome

230844:Kif3b
gene id: 230844:Kif3b
uniprot id: A0A6J0DWU9
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

230844:Pfkfb1
gene id: 230844:Pfkfb1
uniprot id: A0A6I9M3Q3
uniprot id: A0A6J0CQH6
names: Similarity
messages: In the C-terminal section; belongs to the phosphoglycerate mutase family.

230844:Elp4
gene id: 230844:Elp4
uniprot id: A0A6I9L3F8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELP4 family.
messages: Cytoplasm
messages: Nucleus

230844:Sgpl1
gene id: 230844:Sgpl1
uniprot id: A0A6I9L3X2
names: Similarity
messages: Belongs to the group II decarboxylase family.

230844:Setd3
gene id: 230844:Setd3
uniprot id: A0A6I9KVL8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class V-like SAM-binding methyltransferase superfamily. SETD3 actin-histidine methyltransferase family.
messages: Cytoplasm
messages: Interacts with MYOD1.

230844:Ebf2
gene id: 230844:Ebf2
uniprot id: A0A6I9M854
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COE family.
messages: Nucleus

230844:LOC102922870
gene id: 230844:LOC102922870
uniprot id: A0A6I9LLD6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Hpgd
gene id: 230844:Hpgd
uniprot id: A0A6I9KUB0
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

230844:Ppp6c
gene id: 230844:Ppp6c
uniprot id: A0A6I9ME66
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PPP phosphatase family.
messages: Cytoplasm

230844:Pla2g2a
gene id: 230844:Pla2g2a
uniprot id: A0A6I9LDK1
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phospholipase A2 family.
messages: Binds 1 Ca(2+) ion per subunit.
messages: Secreted

230844:Rrp1b
gene id: 230844:Rrp1b
uniprot id: A0A6I9LV66
uniprot id: A0A6J0E8Q7
uniprot id: A0A6J0EG94
names: Similarity
messages: Belongs to the RRP1 family.

230844:Psmc1
gene id: 230844:Psmc1
uniprot id: A0A6I9M2N6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAA ATPase family.
messages: Nucleus

230844:LOC102920414
gene id: 230844:LOC102920414
uniprot id: A0A6I9MFA5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:LOC102910035
gene id: 230844:LOC102910035
uniprot id: A0A6I9LEY2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:LOC102905283
gene id: 230844:LOC102905283
uniprot id: A0A6J0DNC8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2B family.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

230844:Gcgr
gene id: 230844:Gcgr
uniprot id: A0A6J0E3I2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 2 family.
messages: Cell membrane
messages: Membrane

230844:Fam199x
gene id: 230844:Fam199x
uniprot id: A0A6I9MBU7
names: Similarity
messages: Belongs to the FAM199 family.

230844:LOC102925892
gene id: 230844:LOC102925892
uniprot id: A0A6I9LNX2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:LOC102908401
gene id: 230844:LOC102908401
uniprot id: A0A6J0CHV0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:Plec
gene id: 230844:Plec
uniprot id: A0A6I9LS78
uniprot id: A0A6I9LS81
uniprot id: A0A6I9LWL7
uniprot id: A0A6I9LWM2
uniprot id: A0A6I9M2T3
uniprot id: A0A6I9M2U3
uniprot id: A0A6I9M4C9
uniprot id: A0A6I9M8D6
uniprot id: A0A6J0E4B3
uniprot id: A0A6J0E4B9
uniprot id: A0A6J0E4C4
uniprot id: A0A6J0E4C8
uniprot id: A0A6J0E623
uniprot id: A0A6J0E629
uniprot id: A0A6J0E633
uniprot id: A0A6J0E9Y6
uniprot id: A0A6J0E9Z3
uniprot id: A0A6J0EBV3
uniprot id: A0A6J0EBV7
uniprot id: A0A6J0EBW1
names: Similarity
messages: Belongs to the plakin or cytolinker family.

230844:Amotl1
gene id: 230844:Amotl1
uniprot id: A0A6I9M565
uniprot id: A0A6I9M6H4
uniprot id: A0A6J0EB97
names: Similarity
messages: Belongs to the angiomotin family.

230844:Nudt21
gene id: 230844:Nudt21
uniprot id: A0A6I9LV87
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Nudix hydrolase family. CPSF5 subfamily.
messages: Component of the cleavage factor Im (CFIm) complex that functions as an activator of the pre-mRNA 3'-end cleavage and polyadenylation processing required for the maturation of pre-mRNA into functional mRNAs. CFIm contributes to the recruitment of multiprotein complexes on specific sequences on the pre-mRNA 3'-end, so called cleavage and polyadenylation signals (pA signals). Most pre-mRNAs contain multiple pA signals, resulting in alternative cleavage and polyadenylation (APA) producing mRNAs with variable 3'-end formation. The CFIm complex acts as a key regulator of cleavage and polyadenylation site choice during APA through its binding to 5'-UGUA-3' elements localized in the 3'-untranslated region (UTR) for a huge number of pre-mRNAs.
messages: Cytoplasm
messages: Homodimer (via N- and C-terminus); binds RNA as homodimer. Component of the cleavage factor Im (CFIm) complex.
messages: Nucleus

230844:Maml2
gene id: 230844:Maml2
uniprot id: A0A6I9MER6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mastermind family.
messages: Nucleus speckle

230844:Dipk1c
gene id: 230844:Dipk1c
uniprot id: A0A6I9LUL9
names: Similarity
messages: Belongs to the DIPK family.

230844:Il22
gene id: 230844:Il22
uniprot id: A0A6I9KYJ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IL-10 family.
messages: Secreted

230844:Eml1
gene id: 230844:Eml1
uniprot id: A0A6I9KVL5
uniprot id: A0A6I9L568
uniprot id: A0A6J0E2B4
names: Similarity
messages: Belongs to the WD repeat EMAP family.

230844:Fam205c
gene id: 230844:Fam205c
uniprot id: A0A6I9LWN1
names: Similarity
messages: Belongs to the SPATA31 family.

230844:LOC102903197
gene id: 230844:LOC102903197
uniprot id: A0A6J0CTM0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:LOC102914669
gene id: 230844:LOC102914669
uniprot id: A0A6I9LVP6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:LOC102920272
gene id: 230844:LOC102920272
uniprot id: A0A6I9M7M6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

230844:C5H5orf24
gene id: 230844:C5H5orf24
uniprot id: A0A6I9LCM1
names: Similarity
messages: Belongs to the UPF0461 family.

230844:Mc5r
gene id: 230844:Mc5r
uniprot id: A0A6I9KSY6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for MSH (alpha, beta and gamma) and ACTH. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. This receptor is a possible mediator of the immunomodulation properties of melanocortins.

230844:Retreg1
gene id: 230844:Retreg1
uniprot id: A0A6I9LF80
uniprot id: A0A6I9LMH8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RETREG family.
messages: Endoplasmic reticulum membrane
messages: Membrane

230844:Nlgn2
gene id: 230844:Nlgn2
uniprot id: A0A6I9L5H6
uniprot id: A0A6J0CXX6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type-B carboxylesterase/lipase family.
messages: Cell membrane
messages: Membrane

230844:Celsr2
gene id: 230844:Celsr2
uniprot id: A0A6I9LMK8
uniprot id: A0A6J0DF76
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 2 family. LN-TM7 subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Receptor that may have an important role in cell/cell signaling during nervous system formation.

230844:St8sia1
gene id: 230844:St8sia1
uniprot id: A0A6I9M493
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

230844:LOC102914718
gene id: 230844:LOC102914718
uniprot id: A0A6I9MDN4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor T2R family.
messages: Membrane

230844:Mtcl1
gene id: 230844:Mtcl1
uniprot id: A0A6I9M7G7
uniprot id: A0A6J0EAP3
uniprot id: A0A6J0EEG8
uniprot id: A0A6J0EGF0
names: Similarity
messages: Belongs to the SOGA family.

230844:Tmem97
gene id: 230844:Tmem97
uniprot id: A0A6I9L5I5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TMEM97/sigma-2 receptor family.
messages: Endoplasmic reticulum membrane
messages: Interacts with NPC1.
messages: Intracellular orphan receptor that binds numerous drugs and which is highly expressed in various proliferating cells. Corresponds to the sigma-2 receptor, which is thought to play important role in regulating cell survival, morphology and differentiation. May play a role as a regulator of cellular cholesterol homeostasis. May function as sterol isomerase. May alter the activity of some cytochrome P450 proteins.
messages: Membrane
messages: Nucleus membrane
messages: Rough endoplasmic reticulum membrane

230844:Pde6g
gene id: 230844:Pde6g
uniprot id: A0A6J0E3J4
names: Function
names: Similarity
messages: Belongs to the rod/cone cGMP-PDE gamma subunit family.
messages: Participates in processes of transmission and amplification of the visual signal. cGMP-PDEs are the effector molecules in G-protein-mediated phototransduction in vertebrate rods and cones.

230844:Eda2r
gene id: 230844:Eda2r
uniprot id: A0A6I9LE58
uniprot id: A0A6J0DJK8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

230844:Cops4
gene id: 230844:Cops4
uniprot id: A0A6I9L2G5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CSN4 family.
messages: Nucleus
messages: Vesicle
messages: synaptic vesicle

230844:LOC102903801
gene id: 230844:LOC102903801
uniprot id: A0A6I9MPM4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane