230089:VY86 RS13545
gene id: 230089:VY86_RS13545
uniprot id: A0A0F7LQ95
names: Cofactor
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: A single active site specifically recognizes both ATP and CTP and is responsible for their addition.
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. Bacterial CCA-adding enzyme type 1 subfamily.
messages: Catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. tRNA 3'-terminal CCA addition is required both for tRNA processing and repair. Also involved in tRNA surveillance by mediating tandem CCA addition to generate a CCACCA at the 3' terminus of unstable tRNAs. While stable tRNAs receive only 3'-terminal CCA, unstable tRNAs are marked with CCACCA and rapidly degraded.
messages: Comprises two domains: an N-terminal domain containing the nucleotidyltransferase activity and a C-terminal HD domain associated with both phosphodiesterase and phosphatase activities.
messages: Magnesium is required for nucleotidyltransferase activity.
messages: Monomer. Can also form homodimers and oligomers.
messages: Nickel for phosphatase activity.

230089:VY86 RS07165
gene id: 230089:VY86_RS07165
uniprot id: A0A0F7LMY2
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: Allosterically activated by HslU binding.
messages: Belongs to the peptidase T1B family. HslV subfamily.
messages: Cytoplasm
messages: Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.

230089:VY86 RS00105
gene id: 230089:VY86_RS00105
uniprot id: A0A0F7LIV6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the AspA/AstE family. Succinylglutamate desuccinylase subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Transforms N(2)-succinylglutamate into succinate and glutamate.

230089:VY86 RS10855
gene id: 230089:VY86_RS10855
uniprot id: A0A0F7LMG6
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.
messages: In the N-terminal section; belongs to the transposase 2 family.

230089:VY86 RS14990
gene id: 230089:VY86_RS14990
uniprot id: A0A0F7LRI2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ZapD family.
messages: Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity.
messages: Cytoplasm
messages: Interacts with FtsZ.

230089:VY86 RS02305
gene id: 230089:VY86_RS02305
uniprot id: A0A0F7LI01
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family. T3SS ATPase subfamily.
messages: Cytoplasm

230089:VY86 RS05375
gene id: 230089:VY86_RS05375
uniprot id: A0A0F7LLZ3
names: Similarity
messages: Belongs to the threonine synthase family.

230089:VY86 RS08930
gene id: 230089:VY86_RS08930
uniprot id: A0A0F7LN58
names: Function
names: Similarity
messages: Belongs to the FeoC family.
messages: May function as a transcriptional regulator that controls feoABC expression.

230089:VY86 RS17900
gene id: 230089:VY86_RS17900
uniprot id: A0A0F7LNS4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TmcA family.
messages: Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: nucleolus

230089:VY86 RS06905
gene id: 230089:VY86_RS06905
uniprot id: A0A0F7LMJ5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

230089:VY86 RS06255
gene id: 230089:VY86_RS06255
uniprot id: A0A0F7LV78
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

230089:VY86 RS17315
gene id: 230089:VY86_RS17315
uniprot id: A0A0F7LSD9
names: Cofactor
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

230089:VY86 RS12115
gene id: 230089:VY86_RS12115
uniprot id: A0A0F7LN16
names: Similarity
messages: Belongs to the phage portal family. PBSX subfamily.

230089:VY86 RS06335
gene id: 230089:VY86_RS06335
uniprot id: A0A0F7LMH1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

230089:VY86 RS12960
gene id: 230089:VY86_RS12960
uniprot id: A0A0F7LQ18
names: Similarity
messages: Belongs to the glycerate kinase type-1 family.

230089:VY86 RS07670
gene id: 230089:VY86_RS07670
uniprot id: A0A0F7LKT5
names: Similarity
messages: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.

230089:VY86 RS21515
gene id: 230089:VY86_RS21515
uniprot id: A0A0F7LQN2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.
messages: Cell membrane
messages: Membrane
messages: Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

230089:VY86 RS04840
gene id: 230089:VY86_RS04840
uniprot id: A0A0F7LI37
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SNF2/RAD54 helicase family. RapA subfamily.
messages: Interacts with the RNAP. Has a higher affinity for the core RNAP than for the holoenzyme. Its ATPase activity is stimulated by binding to RNAP.
messages: Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair.

230089:VY86 RS01135
gene id: 230089:VY86_RS01135
uniprot id: A0A0F7LJB5
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Fur family.
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.

230089:VY86 RS03635
gene id: 230089:VY86_RS03635
uniprot id: A0A0F7LIU6
names: Cofactor
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.

230089:VY86 RS06695
gene id: 230089:VY86_RS06695
uniprot id: A0A0F7LMH5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the serine/threonine dehydratase family.
messages: Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.
messages: Homotetramer.

230089:VY86 RS02975
gene id: 230089:VY86_RS02975
uniprot id: A0A0F7LKU3
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

230089:VY86 RS15450
gene id: 230089:VY86_RS15450
uniprot id: A0A0F7LS16
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 6-phosphogluconate dehydrogenase family.
messages: Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
messages: Homodimer.

230089:VY86 RS07860
gene id: 230089:VY86_RS07860
uniprot id: A0A0F7LN74
names: Caution
names: Function
names: Similarity
messages: Belongs to the dUTPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

230089:VY86 RS16790
gene id: 230089:VY86_RS16790
uniprot id: A0A0F7LS78
names: Function
names: Similarity
messages: Belongs to the CobT family.
messages: Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB).

230089:VY86 RS01890
gene id: 230089:VY86_RS01890
uniprot id: A0A0F7LKC5
names: Similarity
messages: Belongs to the UPF0125 (RnfH) family.

230089:VY86 RS08065
gene id: 230089:VY86_RS08065
uniprot id: A0A0F7LSX8
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type B subfamily.
messages: Part of the 50S ribosomal subunit.

230089:VY86 RS04705
gene id: 230089:VY86_RS04705
uniprot id: A0A0F7LJE9
names: Similarity
messages: Belongs to the thioesterase family.

230089:VY86 RS01350
gene id: 230089:VY86_RS01350
uniprot id: A0A0F7LGC2
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fluoride channel Fluc/FEX (TC 1.A.43) family.
messages: Cell membrane
messages: Fluoride-specific ion channel. Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane
messages: Na(+) is not transported, but it plays an essential structural role and its presence is essential for fluoride channel function.

230089:VY86 RS05705
gene id: 230089:VY86_RS05705
uniprot id: A0A0F7LLZ7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ThiC family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
messages: Homodimer.

230089:VY86 RS02670
gene id: 230089:VY86_RS02670
uniprot id: A0A0F7LJY3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class II fructose-bisphosphate aldolase family.
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.
messages: Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.

230089:VY86 RS18925
gene id: 230089:VY86_RS18925
uniprot id: A0A0F7LTB8
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the RssB family.
messages: Binds to RpoS.
messages: Phosphorylated. Phosphorylation stimulates the interaction with RpoS and, therefore, the proteolysis of RpoS.
messages: Regulates the turnover of the sigma S factor (RpoS) by promoting its proteolysis in exponentially growing cells. Acts by binding and delivering RpoS to the ClpXP protease. RssB is not co-degraded with RpoS, but is released from the complex and can initiate a new cycle of RpoS recognition and degradation.

230089:VY86 RS16265
gene id: 230089:VY86_RS16265
uniprot id: A0A0F7LS23
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4 family.
messages: Composed of 13 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: Membrane

230089:VY86 RS10660
gene id: 230089:VY86_RS10660
uniprot id: A0A0F7LKQ9
names: Similarity
messages: Belongs to the ner transcriptional regulatory family.

230089:VY86 RS17485
gene id: 230089:VY86_RS17485
uniprot id: A0A0F7LSG9
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
messages: Allosterically activated by GTP.
messages: Belongs to the UPRTase family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.
messages: Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.

230089:VY86 RS12045
gene id: 230089:VY86_RS12045
uniprot id: A0A0F7LLA1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

230089:VY86 RS18445
gene id: 230089:VY86_RS18445
uniprot id: A0A0F7LR34
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.
messages: Cysteine desulfurases mobilize the sulfur from L-cysteine to yield L-alanine, an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Component of the suf operon, which is activated and required under specific conditions such as oxidative stress and iron limitation. Acts as a potent selenocysteine lyase in vitro, that mobilizes selenium from L-selenocysteine. Selenocysteine lyase activity is however unsure in vivo.
messages: Cytoplasm
messages: Homodimer. Interacts with SufE and the SufBCD complex composed of SufB, SufC and SufD. The interaction with SufE is required to mediate the direct transfer of the sulfur atom from the S-sulfanylcysteine.

230089:VY86 RS11000
gene id: 230089:VY86_RS11000
uniprot id: A0A0F7LPK3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HemG family.
messages: Binds 1 FMN non-covalently per subunit.
messages: Catalyzes the 6-electron oxidation of protoporphyrinogen IX to form protoporphyrin IX; under anaerobic conditions uses menaquinone as an electron acceptor, under aerobic conditions uses ubiquinone as an electron acceptor.
messages: Cell membrane

230089:VY86 RS09510
gene id: 230089:VY86_RS09510
uniprot id: A0A0F7LP29
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 5 family.
messages: Periplasm

230089:VY86 RS20040
gene id: 230089:VY86_RS20040
uniprot id: A0A0F7LTT8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ring-hydroxylating dioxygenase alpha subunit family.
messages: Binds 1 Fe cation.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: Part of the multicomponent 3-phenylpropionate dioxygenase. Converts 3-phenylpropionic acid (PP) and cinnamic acid (CI) into 3-phenylpropionate-dihydrodiol (PP-dihydrodiol) and cinnamic acid-dihydrodiol (CI-dihydrodiol), respectively.
messages: This dioxygenase system consists of four proteins: the two subunits of the hydroxylase component (HcaE and HcaF), a ferredoxin (HcaC) and a ferredoxin reductase (HcaD).

230089:VY86 RS18570
gene id: 230089:VY86_RS18570
uniprot id: A0A0F7LR50
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

230089:VY86 RS22325
gene id: 230089:VY86_RS22325
uniprot id: A0A0F7LUQ9
names: Similarity
messages: Belongs to the VgrG protein family.

230089:VY86 RS06995
gene id: 230089:VY86_RS06995
uniprot id: A0A0F7LKG0
names: Function
names: Similarity
messages: Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon.
messages: Belongs to the biotin--protein ligase family.

230089:VY86 RS03690
gene id: 230089:VY86_RS03690
uniprot id: A0A0F7LKM7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm
messages: Purine salvage pathway enzyme which catalyzes the transfer of the ribosyl-5-phosphate group from 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to the N9 position of hypoxanthine to yield IMP (inosine 5'-monophosphate). To a lesser extent, can also act on guanine leading to GMP, but shows a highly less efficient activity with xanthine.

230089:VY86 RS06260
gene id: 230089:VY86_RS06260
uniprot id: A0A0F7LLQ3
names: Function
names: Similarity
messages: Belongs to the band 7/mec-2 family. HflC subfamily.
messages: HflC and HflK could regulate a protease.

230089:VY86 RS13020
gene id: 230089:VY86_RS13020
uniprot id: A0A0F7LQ35
names: Function
names: Similarity
names: Subunit
messages: Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters.
messages: Belongs to the transcriptional regulatory Fis family.
messages: Homodimer.

230089:VY86 RS14190
gene id: 230089:VY86_RS14190
uniprot id: A0A0F7LNX9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbC subfamily.
messages: Periplasm
messages: Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process.

230089:VY86 RS20810
gene id: 230089:VY86_RS20810
uniprot id: A0A0F7LUB8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

230089:VY86 RS04920
gene id: 230089:VY86_RS04920
uniprot id: A0A0F7LJI5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell membrane
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

230089:VY86 RS05235
gene id: 230089:VY86_RS05235
uniprot id: A0A0F7LLE2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acetylates the N-terminal alanine of ribosomal protein bS18.
messages: Belongs to the acetyltransferase family. RimI subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

230089:VY86 RS15400
gene id: 230089:VY86_RS15400
uniprot id: A0A0F7LS10
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.
messages: Homotetramer.

230089:VY86 RS07130
gene id: 230089:VY86_RS07130
uniprot id: A0A0F7LKI8
names: Similarity
names: Subunit
messages: Homotetramer.
messages: In the C-terminal section; belongs to the homoserine dehydrogenase family.
messages: In the N-terminal section; belongs to the aspartokinase family.

230089:VY86 RS14620
gene id: 230089:VY86_RS14620
uniprot id: A0A0F7LMA6
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
messages: In the C-terminal section; belongs to the NAD synthetase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

230089:VY86 RS00240
gene id: 230089:VY86_RS00240
uniprot id: A0A0F7LJN9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TPS (TC 1.B.20) family.
messages: Cell outer membrane
messages: Membrane

230089:VY86 RS06490
gene id: 230089:VY86_RS06490
uniprot id: A0A0F7LK66
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenylyl cyclase class-1 family.
messages: Cytoplasm

230089:VY86 RS17505
gene id: 230089:VY86_RS17505
uniprot id: A0A0F7LSU5
names: Cofactor
names: Similarity
messages: Belongs to the glycosyl hydrolase 4 family.
messages: Binds 1 NAD(+) per subunit.

230089:VY86 RS20060
gene id: 230089:VY86_RS20060
uniprot id: A0A0F7LU23
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the pseudouridine-5'-phosphate glycosidase family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the reversible cleavage of pseudouridine 5'-phosphate (PsiMP) to ribose 5-phosphate and uracil. Functions biologically in the cleavage direction, as part of a pseudouridine degradation pathway.
messages: Homotrimer.

230089:VY86 RS12020
gene id: 230089:VY86_RS12020
uniprot id: A0A0F7LL98
names: Similarity
messages: Belongs to the GSP E family.

230089:VY86 RS03360
gene id: 230089:VY86_RS03360
uniprot id: A0A0F7LKF9
names: Similarity
messages: Belongs to the VgrG protein family.

230089:VY86 RS20615
gene id: 230089:VY86_RS20615
uniprot id: A0A0F7LVG5
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

230089:VY86 RS05180
gene id: 230089:VY86_RS05180
uniprot id: A0A0F7LJK6
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

230089:VY86 RS17515
gene id: 230089:VY86_RS17515
uniprot id: A0A0F7LNF1
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane.

230089:VY86 RS04160
gene id: 230089:VY86_RS04160
uniprot id: A0A0F7LKU8
names: Subcellular Location Annotation
messages: Membrane

230089:VY86 RS08260
gene id: 230089:VY86_RS08260
uniprot id: A0A0F7LNC8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DoxX family.
messages: Membrane

230089:VY86 RS13970
gene id: 230089:VY86_RS13970
uniprot id: A0A0F7LQM0
names: Function
messages: Colicins are polypeptide toxins produced by and active against E.coli and closely related bacteria.

230089:VY86 RS14515
gene id: 230089:VY86_RS14515
uniprot id: A0A0F7LP34
names: Similarity
messages: Belongs to the peptidase M24B family.

230089:VY86 RS12040
gene id: 230089:VY86_RS12040
uniprot id: A0A0F7LPE6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

230089:VY86 RS01900
gene id: 230089:VY86_RS01900
uniprot id: A0A0F7LGL0
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

230089:VY86 RS09010
gene id: 230089:VY86_RS09010
uniprot id: A0A0F7LN62
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Membrane

230089:VY86 RS15855
gene id: 230089:VY86_RS15855
uniprot id: A0A0F7LRJ7
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. CmoM family.
messages: Catalyzes the methylation of 5-carboxymethoxyuridine (cmo5U) to form 5-methoxycarbonylmethoxyuridine (mcmo5U) at position 34 in tRNAs.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

230089:VY86 RS21900
gene id: 230089:VY86_RS21900
uniprot id: A0A0F7LSH5
names: Function
names: Similarity
messages: Belongs to the TrhO family.
messages: Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs.

230089:VY86 RS21435
gene id: 230089:VY86_RS21435
uniprot id: A0A0F7LSA5
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.

230089:VY86 RS14495
gene id: 230089:VY86_RS14495
uniprot id: A0A0F7LR54
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

230089:VY86 RS10405
gene id: 230089:VY86_RS10405
uniprot id: A0A0F7LM97
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.
messages: In the N-terminal section; belongs to the transposase 2 family.

230089:VY86 RS03795
gene id: 230089:VY86_RS03795
uniprot id: A0A0F7LHL0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

230089:VY86 RS09550
gene id: 230089:VY86_RS09550
uniprot id: A0A0F7LK97
names: Subcellular Location Annotation
messages: Membrane

230089:VY86 RS13395
gene id: 230089:VY86_RS13395
uniprot id: A0A0F7LLV1
names: Similarity
messages: Belongs to the UPF0102 family.

230089:VY86 RS13005
gene id: 230089:VY86_RS13005
uniprot id: A0A0F7LNL8
names: Subcellular Location Annotation
messages: Membrane

230089:VY86 RS10430
gene id: 230089:VY86_RS10430
uniprot id: A0A0F7LNT0
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

230089:VY86 RS09110
gene id: 230089:VY86_RS09110
uniprot id: A0A0F7LK13
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

230089:VY86 RS14935
gene id: 230089:VY86_RS14935
uniprot id: A0A0F7LRG1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

230089:VY86 RS12480
gene id: 230089:VY86_RS12480
uniprot id: A0A0F7LPT0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fimbrial export usher family.
messages: Cell outer membrane
messages: Membrane

230089:VY86 RS10295
gene id: 230089:VY86_RS10295
uniprot id: A0A0F7LPC2
names: Similarity
messages: Belongs to the peptidase S13 family.

230089:VY86 RS17240
gene id: 230089:VY86_RS17240
uniprot id: A0A0F7LSC9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. Lipoprotein translocase (TC 3.A.1.125) family.
messages: Cell inner membrane
messages: Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner.
messages: The complex is composed of two ATP-binding proteins (LolD) and two transmembrane proteins (LolC and LolE).

230089:VY86 RS03455
gene id: 230089:VY86_RS03455
uniprot id: A0A0F7LPN2
names: Similarity
messages: Belongs to the transposase 11 family.

230089:VY86 RS22155
gene id: 230089:VY86_RS22155
uniprot id: A0A0F7LSM6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ZapC family.
messages: Contributes to the efficiency of the cell division process by stabilizing the polymeric form of the cell division protein FtsZ. Acts by promoting interactions between FtsZ protofilaments and suppressing the GTPase activity of FtsZ.
messages: Cytoplasm
messages: Interacts directly with FtsZ.

230089:VY86 RS22130
gene id: 230089:VY86_RS22130
uniprot id: A0A0F7LUN9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RlmKL family.
messages: Cytoplasm
messages: Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA.

230089:VY86 RS12100
gene id: 230089:VY86_RS12100
uniprot id: A0A0F7LQ58
names: Function
names: Similarity
messages: Belongs to the phage GPA family.
messages: Possible endonuclease which induces a single-strand cut and initiates DNA replication.

230089:VY86 RS05830
gene id: 230089:VY86_RS05830
uniprot id: A0A0F7LIF8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the porin LamB (TC 1.B.3) family.
messages: Membrane

230089:VY86 RS05280
gene id: 230089:VY86_RS05280
uniprot id: A0A0F7LLY2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PNP/UDP phosphorylase family.
messages: Catalyzes the reversible phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.
messages: Homohexamer; trimer of homodimers.

230089:VY86 RS04235
gene id: 230089:VY86_RS04235
uniprot id: A0A0F7LLK7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gmhB family.
messages: Cytoplasm

230089:VY86 RS14430
gene id: 230089:VY86_RS14430
uniprot id: A0A0F7LR36
names: Function
names: Similarity
messages: Belongs to the alpha-ketoglutarate dehydrogenase family.
messages: E1 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the decarboxylation of 2-oxoglutarate, the first step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).

230089:VY86 RS10570
gene id: 230089:VY86_RS10570
uniprot id: A0A0F7LPG8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm

230089:VY86 RS13255
gene id: 230089:VY86_RS13255
uniprot id: A0A0F7LQP7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptC family.
messages: Cell inner membrane
messages: Component of the lipopolysaccharide transport and assembly complex. Interacts with LptA and the LptBFG transporter complex.
messages: Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. Facilitates the transfer of LPS from the inner membrane to the periplasmic protein LptA. Could be a docking site for LptA.
messages: Required for the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane.

230089:VY86 RS07740
gene id: 230089:VY86_RS07740
uniprot id: A0A0F7LKV0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the zinc-containing alcohol dehydrogenase family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the NAD(+)-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate.
messages: Cytoplasm
messages: Homotetramer.

230089:VY86 RS16845
gene id: 230089:VY86_RS16845
uniprot id: A0A0F7LVI2
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

230089:VY86 RS00600
gene id: 230089:VY86_RS00600
uniprot id: A0A0F7LJ09
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Monomer.

230089:VY86 RS08560
gene id: 230089:VY86_RS08560
uniprot id: A0A0F7LMY8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family. Pit subfamily.
messages: Membrane

230089:VY86 RS02070
gene id: 230089:VY86_RS02070
uniprot id: A0A0F7LGN8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E.
messages: Belongs to the RseA family.
messages: Cell inner membrane
messages: Interacts 1:1 with ECF RNA polymerase sigma-E (RpoE); this inhibits the interaction of sigma-E with the RNA polymerase catalytic core and leads to a decreased expression of sigma-E-regulated genes. Interacts with RseB.

230089:VY86 RS13790
gene id: 230089:VY86_RS13790
uniprot id: A0A0F7LQC9
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

230089:VY86 RS18350
gene id: 230089:VY86_RS18350
uniprot id: A0A0F7LR23
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

230089:VY86 RS07170
gene id: 230089:VY86_RS07170
uniprot id: A0A0F7LM82
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
messages: Belongs to the ClpX chaperone family. HslU subfamily.
messages: Cytoplasm

230089:VY86 RS02335
gene id: 230089:VY86_RS02335
uniprot id: A0A0F7LI03
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliR/MopE/SpaR family.
messages: Cell membrane
messages: Membrane

230089:VY86 RS11910
gene id: 230089:VY86_RS11910
uniprot id: A0A0F7LL84
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: Membrane
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

230089:VY86 RS07880
gene id: 230089:VY86_RS07880
uniprot id: A0A0F7LN78
names: Similarity
messages: Belongs to the YicC/YloC family.

230089:VY86 RS20410
gene id: 230089:VY86_RS20410
uniprot id: A0A0F7LTY0
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvA family.
messages: Cytoplasm
messages: Has three domains with a flexible linker between the domains II and III and assumes an 'L' shape. Domain III is highly mobile and contacts RuvB.
messages: Homotetramer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

230089:VY86 RS01990
gene id: 230089:VY86_RS01990
uniprot id: A0A0F7LK93
names: Similarity
messages: Belongs to the transposase 11 family.

230089:VY86 RS00535
gene id: 230089:VY86_RS00535
uniprot id: A0A0F7LJL5
names: Similarity
messages: Belongs to the UPF0115 family.

230089:VY86 RS13215
gene id: 230089:VY86_RS13215
uniprot id: A0A0F7LLT5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rnk family.
messages: Interacts with the RNA polymerase.
messages: May act as an anti-Gre factor.

230089:VY86 RS00490
gene id: 230089:VY86_RS00490
uniprot id: A0A0F7LJS4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

230089:VY86 RS12975
gene id: 230089:VY86_RS12975
uniprot id: A0A0F7LNL7
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

230089:VY86 RS03835
gene id: 230089:VY86_RS03835
uniprot id: A0A0F7LHL3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dGTPase family. Type 1 subfamily.
messages: Homotetramer.
messages: dGTPase preferentially hydrolyzes dGTP over the other canonical NTPs.

230089:VY86 RS09105
gene id: 230089:VY86_RS09105
uniprot id: A0A0F7LN65
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glutamine synthetase family.
messages: Catalyzes the ATP-dependent biosynthesis of glutamine from glutamate and ammonia.
messages: Cytoplasm
messages: Oligomer of 12 subunits arranged in the form of two hexagons.

230089:VY86 RS04545
gene id: 230089:VY86_RS04545
uniprot id: A0A0F7LLF9
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

230089:VY86 RS13145
gene id: 230089:VY86_RS13145
uniprot id: A0A0F7LQF1
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

230089:VY86 RS07085
gene id: 230089:VY86_RS07085
uniprot id: A0A0F7LMS4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

230089:VY86 RS02775
gene id: 230089:VY86_RS02775
uniprot id: A0A0F7LKP5
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

230089:VY86 RS10385
gene id: 230089:VY86_RS10385
uniprot id: A0A0F7LPD5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DEAD box helicase family. DeaD/CsdA subfamily.
messages: Cytoplasm
messages: DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation.

230089:VY86 RS14745
gene id: 230089:VY86_RS14745
uniprot id: A0A0F7LMB6
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

230089:VY86 RS06110
gene id: 230089:VY86_RS06110
uniprot id: A0A0F7LK02
names: Similarity
messages: Belongs to the phosphoribulokinase family.

230089:VY86 RS02515
gene id: 230089:VY86_RS02515
uniprot id: A0A0F7LKH9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the branched chain amino acid transporter family.
messages: Cell inner membrane
messages: Component of the transport system for branched-chain amino acids.
messages: Membrane

230089:VY86 RS18960
gene id: 230089:VY86_RS18960
uniprot id: A0A0F7LTA1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell membrane
messages: Membrane

230089:VY86 RS16205
gene id: 230089:VY86_RS16205
uniprot id: A0A0F7LMU6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

230089:VY86 RS10315
gene id: 230089:VY86_RS10315
uniprot id: A0A0F7LP98
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

230089:VY86 RS14520
gene id: 230089:VY86_RS14520
uniprot id: A0A0F7LR55
names: Similarity
messages: Belongs to the UPF0149 family.

230089:VY86 RS20670
gene id: 230089:VY86_RS20670
uniprot id: A0A0F7LU08
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

230089:VY86 RS10600
gene id: 230089:VY86_RS10600
uniprot id: A0A0F7LNU4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Membrane

230089:VY86 RS03570
gene id: 230089:VY86_RS03570
uniprot id: A0A0F7LHH9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsB family.
messages: Cell inner membrane
messages: Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.
messages: Part of a complex composed of FtsB, FtsL and FtsQ.

230089:VY86 RS12230
gene id: 230089:VY86_RS12230
uniprot id: A0A0F7LLD0
names: Similarity
messages: Belongs to the ner transcriptional regulatory family.

230089:VY86 RS03100
gene id: 230089:VY86_RS03100
uniprot id: A0A0F7LH57
names: Function
messages: Catalyzes the dismutation of two molecules of 6,7-dimethyl-8-ribityllumazine, resulting in the formation of riboflavin and 5-amino-6-(D-ribitylamino)uracil.

230089:VY86 RS12475
gene id: 230089:VY86_RS12475
uniprot id: A0A0F7LQG1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the periplasmic pilus chaperone family.
messages: Periplasm

230089:VY86 RS03495
gene id: 230089:VY86_RS03495
uniprot id: A0A0F7LIR0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

230089:VY86 RS02695
gene id: 230089:VY86_RS02695
uniprot id: A0A0F7LKN9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThiI family.
messages: Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

230089:VY86 RS03705
gene id: 230089:VY86_RS03705
uniprot id: A0A0F7LL10
names: Function
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

230089:VY86 RS16850
gene id: 230089:VY86_RS16850
uniprot id: A0A0F7LS88
names: Function
messages: Decarboxylates L-threonine-O-3-phosphate to yield (R)-1-amino-2-propanol O-2-phosphate, the precursor for the linkage between the nucleotide loop and the corrin ring in cobalamin.

230089:VY86 RS20840
gene id: 230089:VY86_RS20840
uniprot id: A0A0F7LKS9
names: Similarity
messages: Belongs to the transposase 11 family.

230089:VY86 RS04790
gene id: 230089:VY86_RS04790
uniprot id: A0A0F7LI24
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell membrane

230089:VY86 RS17300
gene id: 230089:VY86_RS17300
uniprot id: A0A0F7LQG4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA(Lys), tRNA(Glu) and tRNA(Gln), leading to the formation of s(2)U34, the first step of tRNA-mnm(5)s(2)U34 synthesis. Sulfur is provided by IscS, via a sulfur-relay system. Binds ATP and its substrate tRNAs.
messages: Cytoplasm
messages: Interacts with TusE.

230089:VY86 RS00630
gene id: 230089:VY86_RS00630
uniprot id: A0A0F7LJM5
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

230089:VY86 RS05230
gene id: 230089:VY86_RS05230
uniprot id: A0A0F7LLX7
names: Function
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is unknown.

230089:VY86 RS04345
gene id: 230089:VY86_RS04345
uniprot id: A0A0F7LLL4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Cytoplasm
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
messages: The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.

230089:VY86 RS17560
gene id: 230089:VY86_RS17560
uniprot id: A0A0F7LSV1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

230089:VY86 RS21210
gene id: 230089:VY86_RS21210
uniprot id: A0A0F7LUD1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the FliF family.
messages: Membrane
messages: The M ring may be actively involved in energy transduction.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The M ring is integral to the inner membrane of the cell and may be connected to the flagellar rod via the S ring. The S (supramembrane ring) lies just distal to the M ring. The L and P rings lie in the outer membrane and the periplasmic space, respectively.

230089:VY86 RS10845
gene id: 230089:VY86_RS10845
uniprot id: A0A0F7LKS6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

230089:VY86 RS06600
gene id: 230089:VY86_RS06600
uniprot id: A0A0F7LLY1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. WecA subfamily.
messages: Catalyzes the transfer of the GlcNAc-1-phosphate moiety from UDP-GlcNAc onto the carrier lipid undecaprenyl phosphate (C55-P), yielding GlcNAc-pyrophosphoryl-undecaprenyl (GlcNAc-PP-C55).
messages: Cell inner membrane
messages: Membrane

230089:VY86 RS13210
gene id: 230089:VY86_RS13210
uniprot id: A0A0F7LQ54
names: Similarity
messages: Belongs to the peptidase U62 family.

230089:VY86 RS14175
gene id: 230089:VY86_RS14175
uniprot id: A0A0F7LRA2
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

230089:VY86 RS00150
gene id: 230089:VY86_RS00150
uniprot id: A0A0F7LJE2
names: Similarity
messages: Belongs to the bacterial ring-hydroxylating dioxygenase beta subunit family.

230089:VY86 RS18525
gene id: 230089:VY86_RS18525
uniprot id: A0A0F7LT65
names: Domain
names: Function
names: Subunit
messages: Consists of two structural and functional domains: an N-terminal DNA-binding domain, approximately the first 60 residues, and a larger C-terminal domain, approximately 280 residues, which imparts the function of corepressor binding and oligomerization.
messages: Homodimer.
messages: Is the main repressor of the genes involved in the de novo synthesis of purine nucleotides, regulating purB, purC, purEK, purF, purHD, purL, purMN and guaBA expression. PurR is allosterically activated to bind its cognate DNA by binding the purine corepressors, hypoxanthine or guanine, thereby effecting transcription repression.

230089:VY86 RS14370
gene id: 230089:VY86_RS14370
uniprot id: A0A0F7LNZ7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TolB family.
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity. TolB occupies a key intermediary position in the Tol-Pal system because it communicates directly with both membrane-embedded components, Pal in the outer membrane and TolA in the inner membrane.
messages: Periplasm
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

230089:VY86 RS14315
gene id: 230089:VY86_RS14315
uniprot id: A0A0F7LRC7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: Homodimer.

230089:VY86 RS07920
gene id: 230089:VY86_RS07920
uniprot id: A0A0F7LJL2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FdhE family.
messages: Cytoplasm
messages: Necessary for formate dehydrogenase activity.

230089:VY86 RS19025
gene id: 230089:VY86_RS19025
uniprot id: A0A0F7LRA5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YciB family.
messages: Cell inner membrane
messages: Plays a role in cell envelope biogenesis, maintenance of cell envelope integrity and membrane homeostasis.

230089:VY86 RS08800
gene id: 230089:VY86_RS08800
uniprot id: A0A0F7LN47
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.

230089:VY86 RS11290
gene id: 230089:VY86_RS11290
uniprot id: A0A0F7LPN2
names: Similarity
messages: Belongs to the transposase 11 family.

230089:VY86 RS19355
gene id: 230089:VY86_RS19355
uniprot id: A0A0F7LPM9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfB subfamily.
messages: Binds 3 [4Fe-4S] clusters.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

230089:VY86 RS22175
gene id: 230089:VY86_RS22175
uniprot id: A0A0F7LQW6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

230089:VY86 RS05940
gene id: 230089:VY86_RS05940
uniprot id: A0A0F7LLK8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NusG family.
messages: Monomer. Interacts with the transcription termination factor Rho and with RNA polymerase.
messages: Participates in transcription elongation, termination and antitermination. In the absence of Rho, increases the rate of transcription elongation by the RNA polymerase (RNAP), probably by partially suppressing pausing. In the presence of Rho, modulates most Rho-dependent termination events by interacting with the RNAP to render the complex more susceptible to the termination activity of Rho. May be required to overcome a kinetic limitation of Rho to function at certain terminators. Also involved in ribosomal RNA transcriptional antitermination.

230089:VY86 RS10930
gene id: 230089:VY86_RS10930
uniprot id: A0A0F7LPK6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC1 family. UbiB subfamily.
messages: Cell membrane
messages: Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

230089:VY86 RS02715
gene id: 230089:VY86_RS02715
uniprot id: A0A0F7LUU8
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
messages: Carbon 2 of the heme B porphyrin ring is defined according to the Fischer nomenclature.
messages: Cell membrane
messages: Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
messages: Membrane

230089:VY86 RS18520
gene id: 230089:VY86_RS18520
uniprot id: A0A0F7LTG0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

230089:VY86 RS21180
gene id: 230089:VY86_RS21180
uniprot id: A0A0F7LUM5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

230089:VY86 RS20700
gene id: 230089:VY86_RS20700
uniprot id: A0A0F7LU13
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Cell inner membrane
messages: Membrane

230089:VY86 RS09545
gene id: 230089:VY86_RS09545
uniprot id: A0A0F7LNJ1
names: Similarity
messages: Belongs to the 4-oxalocrotonate tautomerase family.

230089:VY86 RS18185
gene id: 230089:VY86_RS18185
uniprot id: A0A0F7LT95
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial histone-like protein family.
messages: Heterodimer of an alpha and a beta chain.
messages: This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.

230089:VY86 RS21765
gene id: 230089:VY86_RS21765
uniprot id: A0A0F7LSG0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. TCR/Tet family.
messages: Membrane
messages: Resistance to tetracycline by an active tetracycline efflux. This is an energy-dependent process that decreases the accumulation of the antibiotic in whole cells. This protein functions as a metal-tetracycline/H(+) antiporter.

230089:VY86 RS14820
gene id: 230089:VY86_RS14820
uniprot id: A0A0F7LMC7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Homodimer.

230089:VY86 RS02590
gene id: 230089:VY86_RS02590
uniprot id: A0A0F7LI78
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

230089:VY86 RS08080
gene id: 230089:VY86_RS08080
uniprot id: A0A0F7LN97
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

230089:VY86 RS13205
gene id: 230089:VY86_RS13205
uniprot id: A0A0F7LQP3
names: Similarity
messages: Belongs to the UPF0307 family.

230089:VY86 RS00500
gene id: 230089:VY86_RS00500
uniprot id: A0A0F7LG33
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmB subfamily.
messages: Methylates ribosomal protein uL3 on a specific glutamine residue.

230089:VY86 RS01195
gene id: 230089:VY86_RS01195
uniprot id: A0A0F7LJX8
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

230089:VY86 RS05980
gene id: 230089:VY86_RS05980
uniprot id: A0A0F7LM37
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DsrE/TusD family.
messages: Cytoplasm
messages: Heterohexamer, formed by a dimer of trimers. The hexameric TusBCD complex contains 2 copies each of TusB, TusC and TusD. The TusBCD complex interacts with TusE.
messages: Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE.

230089:VY86 RS03885
gene id: 230089:VY86_RS03885
uniprot id: A0A0F7LKR7
names: Subcellular Location Annotation
messages: Membrane

230089:VY86 RS20425
gene id: 230089:VY86_RS20425
uniprot id: A0A0F7LTY7
names: Cofactor
messages: Binds 1 Mg(2+) ion per subunit.

230089:VY86 RS04015
gene id: 230089:VY86_RS04015
uniprot id: A0A0F7LLC5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fimbrial export usher family.
messages: Cell outer membrane
messages: Membrane

230089:VY86 RS07075
gene id: 230089:VY86_RS07075
uniprot id: A0A0F7LJ32
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.

230089:VY86 RS06495
gene id: 230089:VY86_RS06495
uniprot id: A0A0F7LMF8
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HMBS family.
messages: Binds 1 dipyrromethane group covalently.
messages: Monomer.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
messages: The porphobilinogen subunits are added to the dipyrromethane group.

230089:VY86 RS02785
gene id: 230089:VY86_RS02785
uniprot id: A0A0F7LH11
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

230089:VY86 RS08455
gene id: 230089:VY86_RS08455
uniprot id: A0A0F7LND4
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

230089:VY86 RS03120
gene id: 230089:VY86_RS03120
uniprot id: A0A0F7LK75
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

230089:VY86 RS21430
gene id: 230089:VY86_RS21430
uniprot id: A0A0F7LQM9
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.

230089:VY86 RS01110
gene id: 230089:VY86_RS01110
uniprot id: A0A0F7LG90
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
messages: Cell inner membrane

230089:VY86 RS21270
gene id: 230089:VY86_RS21270
uniprot id: A0A0F7LQL7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliR/MopE/SpaR family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

230089:VY86 RS08325
gene id: 230089:VY86_RS08325
uniprot id: A0A0F7LJS0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family.
messages: Monomer.
messages: Specifically catalyzes the dephosphorylation of 2-phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress.

230089:VY86 RS19900
gene id: 230089:VY86_RS19900
uniprot id: A0A0F7LTQ1
names: Subunit
messages: Monomer.

230089:VY86 RS20150
gene id: 230089:VY86_RS20150
uniprot id: A0A0F7LPZ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NiCoT transporter (TC 2.A.52) family. RcnA subfamily.
messages: Cell membrane
messages: Efflux system for nickel and cobalt.
messages: Membrane

230089:VY86 RS18065
gene id: 230089:VY86_RS18065
uniprot id: A0A0F7LNV2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CopC family.
messages: Involved in copper resistance.
messages: Periplasm

230089:VY86 RS11135
gene id: 230089:VY86_RS11135
uniprot id: A0A0F7LKV9
names: Function
names: Similarity
messages: Belongs to the QueH family.
messages: Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr).

230089:VY86 RS13705
gene id: 230089:VY86_RS13705
uniprot id: A0A0F7LM02
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 1 subfamily.
messages: Cell membrane
messages: Heterotetramer composed of ParC and ParE.
messages: Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.

230089:VY86 RS09430
gene id: 230089:VY86_RS09430
uniprot id: A0A0F7LK84
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

230089:VY86 RS03765
gene id: 230089:VY86_RS03765
uniprot id: A0A0F7LKP4
names: Function
names: Similarity
messages: Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits).
messages: In the C-terminal section; belongs to the transpeptidase family.
messages: In the N-terminal section; belongs to the glycosyltransferase 51 family.

230089:VY86 RS13605
gene id: 230089:VY86_RS13605
uniprot id: A0A0F7LLX2
names: Similarity
messages: Belongs to the DODA-type extradiol aromatic ring-opening dioxygenase family.

230089:VY86 RS05725
gene id: 230089:VY86_RS05725
uniprot id: A0A0F7LJS3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ThiG family.
messages: Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
messages: Cytoplasm
messages: Homotetramer. Forms heterodimers with either ThiH or ThiS.

230089:VY86 RS04935
gene id: 230089:VY86_RS04935
uniprot id: A0A0F7LL79
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

230089:VY86 RS02660
gene id: 230089:VY86_RS02660
uniprot id: A0A0F7LKJ5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. Epd subfamily.
messages: Catalyzes the NAD-dependent conversion of D-erythrose 4-phosphate to 4-phosphoerythronate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

230089:VY86 RS16085
gene id: 230089:VY86_RS16085
uniprot id: A0A0F7LS89
names: Similarity
messages: Belongs to the myoviridae tail sheath protein family.

230089:VY86 RS06935
gene id: 230089:VY86_RS06935
uniprot id: A0A0F7LMU8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

230089:VY86 RS13595
gene id: 230089:VY86_RS13595
uniprot id: A0A0F7LQV2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiK family.
messages: Cytoplasm
messages: Required for efficient ubiquinone (coenzyme Q) biosynthesis. UbiK is probably an accessory factor of Ubi enzymes and facilitates ubiquinone biosynthesis by acting as an assembly factor, a targeting factor, or both.

230089:VY86 RS15710
gene id: 230089:VY86_RS15710
uniprot id: A0A0F7LKS9
names: Similarity
messages: Belongs to the transposase 11 family.

230089:VY86 RS21230
gene id: 230089:VY86_RS21230
uniprot id: A0A0F7LUN3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliJ family.
messages: Cell membrane
messages: Flagellar protein that affects chemotactic events.
messages: Membrane

230089:VY86 RS00300
gene id: 230089:VY86_RS00300
uniprot id: A0A0F7LJE6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LsrG family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the degradation of phospho-AI-2, thereby terminating induction of the lsr operon and closing the AI-2 signaling cycle. Catalyzes the conversion of (4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione (P-DPD) to 3-hydroxy-5-phosphonooxypentane-2,4-dione (P-HPD).

230089:VY86 RS20855
gene id: 230089:VY86_RS20855
uniprot id: A0A0F7LU78
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

230089:VY86 RS07225
gene id: 230089:VY86_RS07225
uniprot id: A0A0F7LJ70
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by ADP and other diphosphonucleosides, and allosterically inhibited by phosphoenolpyruvate.
messages: Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Prokaryotic clade 'B1' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

230089:VY86 RS10085
gene id: 230089:VY86_RS10085
uniprot id: A0A0F7LP93
names: Similarity
messages: Belongs to the ClpA/ClpB family.

230089:VY86 RS05690
gene id: 230089:VY86_RS05690
uniprot id: A0A0F7LIE7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the uroporphyrinogen decarboxylase family.
messages: Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

230089:VY86 RS10250
gene id: 230089:VY86_RS10250
uniprot id: A0A0F7LNQ8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ArgR family.
messages: Cytoplasm
messages: Regulates arginine biosynthesis genes.

230089:VY86 RS11655
gene id: 230089:VY86_RS11655
uniprot id: A0A0F7LPX7
names: Similarity
messages: Belongs to the glycosyl hydrolase 24 family.

230089:VY86 RS18560
gene id: 230089:VY86_RS18560
uniprot id: A0A0F7LVK1
names: Function
names: Similarity
messages: Belongs to the anhydro-N-acetylmuramic acid kinase family.
messages: Catalyzes the specific phosphorylation of 1,6-anhydro-N-acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling.

230089:VY86 RS17040
gene id: 230089:VY86_RS17040
uniprot id: A0A0F7LS72
names: Cofactor
messages: Binds 2 Mg(2+) ions per monomer.

230089:VY86 RS10700
gene id: 230089:VY86_RS10700
uniprot id: A0A0F7LME7
names: Similarity
messages: Belongs to the AAA ATPase family.

230089:VY86 RS08745
gene id: 230089:VY86_RS08745
uniprot id: A0A0F7LN05
names: Similarity
messages: Belongs to the transposase 11 family.

230089:VY86 RS00335
gene id: 230089:VY86_RS00335
uniprot id: A0A0F7LJH9
names: Similarity
messages: Belongs to the Nudix hydrolase family.

230089:VY86 RS16865
gene id: 230089:VY86_RS16865
uniprot id: A0A0F7LS42
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Cob(I)alamin adenosyltransferase family.
messages: Cytoplasm
messages: Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids.

230089:VY86 RS10195
gene id: 230089:VY86_RS10195
uniprot id: A0A0F7LPB6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TamA family.
messages: Cell outer membrane
messages: Membrane

230089:VY86 RS06805
gene id: 230089:VY86_RS06805
uniprot id: A0A0F7LMT3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Cytoplasm
messages: Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.

230089:VY86 RS07750
gene id: 230089:VY86_RS07750
uniprot id: A0A0F7LN52
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. HldD subfamily.
messages: Binds 1 NADP(+) per subunit.
messages: Catalyzes the interconversion between ADP-D-glycero-beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose.
messages: Contains a large N-terminal NADP-binding domain, and a smaller C-terminal substrate-binding domain.
messages: Homopentamer.

230089:VY86 RS20250
gene id: 230089:VY86_RS20250
uniprot id: A0A0F7LU55
names: Similarity
messages: Belongs to the UPF0260 family.

230089:VY86 RS07185
gene id: 230089:VY86_RS07185
uniprot id: A0A0F7LMV6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ZapB family.
messages: Cytoplasm
messages: Homodimer. The ends of the coiled-coil dimer bind to each other, forming polymers. Interacts with FtsZ.
messages: Non-essential, abundant cell division factor that is required for proper Z-ring formation. It is recruited early to the divisome by direct interaction with FtsZ, stimulating Z-ring assembly and thereby promoting cell division earlier in the cell cycle. Its recruitment to the Z-ring requires functional FtsA or ZipA.

230089:VY86 RS15740
gene id: 230089:VY86_RS15740
uniprot id: A0A0F7LRH2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Activation of pyruvate formate-lyase 1 under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.
messages: Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.
messages: Belongs to the organic radical-activating enzymes family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm

230089:VY86 RS18340
gene id: 230089:VY86_RS18340
uniprot id: A0A0F7LT38
names: Function
names: Similarity
messages: Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PSRP subfamily.
messages: Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation/dephosphorylation.

230089:VY86 RS07970
gene id: 230089:VY86_RS07970
uniprot id: A0A0F7LN81
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
messages: Binds 1 potassium ion per subunit.
messages: Cytoplasm
messages: Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

230089:VY86 RS18950
gene id: 230089:VY86_RS18950
uniprot id: A0A0F7LTC0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidine kinase family.
messages: Cytoplasm
messages: Homotetramer.

230089:VY86 RS01235
gene id: 230089:VY86_RS01235
uniprot id: A0A0F7LJC1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methylthiotransferase family. MiaB subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
messages: Cytoplasm
messages: Monomer.

230089:VY86 RS12035
gene id: 230089:VY86_RS12035
uniprot id: A0A0F7LQ49
names: Similarity
messages: Belongs to the YggT family.

230089:VY86 RS02525
gene id: 230089:VY86_RS02525
uniprot id: A0A0F7LJW1
names: Function
messages: This protein is a positive regulator for the phosphate regulon. Transcription of this operon is positively regulated by PhoB and PhoR when phosphate is limited.

230089:VY86 RS08390
gene id: 230089:VY86_RS08390
uniprot id: A0A0F7LND2
names: Similarity
messages: Belongs to the HSP15 family.

230089:VY86 RS18325
gene id: 230089:VY86_RS18325
uniprot id: A0A0F7LR21
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

230089:VY86 RS06920
gene id: 230089:VY86_RS06920
uniprot id: A0A0F7LJ18
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

230089:VY86 RS15630
gene id: 230089:VY86_RS15630
uniprot id: A0A0F7LRV3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ClpS family.
messages: Binds to the N-terminal domain of the chaperone ClpA.
messages: Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation.

230089:VY86 RS03850
gene id: 230089:VY86_RS03850
uniprot id: A0A0F7LL24
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

230089:VY86 RS01640
gene id: 230089:VY86_RS01640
uniprot id: A0A0F7LHV7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

230089:VY86 RS20355
gene id: 230089:VY86_RS20355
uniprot id: A0A0F7LU72
names: Similarity
messages: Belongs to the pyruvate kinase family.

230089:VY86 RS14365
gene id: 230089:VY86_RS14365
uniprot id: A0A0F7LM73
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Pal lipoprotein family.
messages: Cell outer membrane
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

230089:VY86 RS13550
gene id: 230089:VY86_RS13550
uniprot id: A0A0F7LLX0
names: Subcellular Location Annotation
messages: Membrane

230089:VY86 RS11230
gene id: 230089:VY86_RS11230
uniprot id: A0A0F7LPM0
names: Similarity
messages: Belongs to the MbcT/ParT/Res family.

230089:VY86 RS02930
gene id: 230089:VY86_RS02930
uniprot id: A0A0F7LK44
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

230089:VY86 RS13345
gene id: 230089:VY86_RS13345
uniprot id: A0A0F7LLU4
names: Similarity
messages: Belongs to the GST superfamily. HSP26 family.

230089:VY86 RS07680
gene id: 230089:VY86_RS07680
uniprot id: A0A0F7LV82
names: Function
names: Similarity
messages: Belongs to the transposase 11 family.
messages: Involved in the transposition of the insertion sequence IS5.

230089:VY86 RS15605
gene id: 230089:VY86_RS15605
uniprot id: A0A0F7LRU9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Membrane

230089:VY86 RS02325
gene id: 230089:VY86_RS02325
uniprot id: A0A0F7LJT7
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliP/MopC/SpaP family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

230089:VY86 RS00115
gene id: 230089:VY86_RS00115
uniprot id: A0A0F7LH87
names: Function
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family. AstD subfamily.
messages: Catalyzes the NAD-dependent reduction of succinylglutamate semialdehyde into succinylglutamate.

230089:VY86 RS03055
gene id: 230089:VY86_RS03055
uniprot id: A0A0F7LII0
names: Similarity
messages: Belongs to the band 7/mec-2 family.

230089:VY86 RS14640
gene id: 230089:VY86_RS14640
uniprot id: A0A0F7LQU8
names: Similarity
messages: Belongs to the phD/YefM antitoxin family.

230089:VY86 RS11955
gene id: 230089:VY86_RS11955
uniprot id: A0A0F7LPD3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

230089:VY86 RS10280
gene id: 230089:VY86_RS10280
uniprot id: A0A0F7LKG1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

230089:VY86 RS20180
gene id: 230089:VY86_RS20180
uniprot id: A0A0F7LQ12
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm
messages: chloroplast

230089:VY86 RS02875
gene id: 230089:VY86_RS02875
uniprot id: A0A0F7LKS0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CbiQ family.
messages: Membrane

230089:VY86 RS01490
gene id: 230089:VY86_RS01490
uniprot id: A0A0F7LGD9
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

230089:VY86 RS12955
gene id: 230089:VY86_RS12955
uniprot id: A0A0F7LQK7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoH subfamily.
messages: Cytoplasm
messages: Interacts with the RNA polymerase core enzyme.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes.

230089:VY86 RS01615
gene id: 230089:VY86_RS01615
uniprot id: A0A0F7LK18
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

230089:VY86 RS20375
gene id: 230089:VY86_RS20375
uniprot id: A0A0F7LTY1
names: Similarity
messages: Belongs to the radical SAM superfamily. Anaerobic sulfatase-maturating enzyme family.

230089:VY86 RS19155
gene id: 230089:VY86_RS19155
uniprot id: A0A0F7LTE0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LapB family.
messages: Cell inner membrane
messages: Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane.

230089:VY86 RS17115
gene id: 230089:VY86_RS17115
uniprot id: A0A0F7LSB4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YceF subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes 7-methyl-GTP (m(7)GTP). May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

230089:VY86 RS00475
gene id: 230089:VY86_RS00475
uniprot id: A0A0F7LG32
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Catalyzes the last two steps in the biosynthesis of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the DAO family.
messages: In the N-terminal section; belongs to the methyltransferase superfamily. tRNA (mnm(5)s(2)U34)-methyltransferase family.

230089:VY86 RS02505
gene id: 230089:VY86_RS02505
uniprot id: A0A0F7LGV6
names: Similarity
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.

230089:VY86 RS06175
gene id: 230089:VY86_RS06175
uniprot id: A0A0F7LK10
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inositol monophosphatase superfamily. CysQ family.
messages: Cell inner membrane
messages: Converts adenosine-3',5'-bisphosphate (PAP) to AMP.

230089:VY86 RS01575
gene id: 230089:VY86_RS01575
uniprot id: A0A0F7LKA4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LuxS family.
messages: Binds 1 Fe cation per subunit.
messages: Homodimer.
messages: Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD).

230089:VY86 RS16430
gene id: 230089:VY86_RS16430
uniprot id: A0A0F7LSG2
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

230089:VY86 RS13270
gene id: 230089:VY86_RS13270
uniprot id: A0A0F7LNP4
names: Subcellular Location Annotation
messages: Membrane

230089:VY86 RS07980
gene id: 230089:VY86_RS07980
uniprot id: A0A0F7LJM2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0161 family.
messages: Cell membrane
messages: Could be involved in insertion of integral membrane proteins into the membrane.

230089:VY86 RS14545
gene id: 230089:VY86_RS14545
uniprot id: A0A0F7LR56
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LysR transcriptional regulatory family.
messages: Controls the transcription of genes involved in arginine and lysine metabolism.
messages: Homodimer.

230089:VY86 RS07720
gene id: 230089:VY86_RS07720
uniprot id: A0A0F7LN49
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecB family.
messages: Cytoplasm
messages: Homotetramer, a dimer of dimers. One homotetramer interacts with 1 SecA dimer.
messages: One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA.

230089:VY86 RS06620
gene id: 230089:VY86_RS06620
uniprot id: A0A0F7LR46
names: Function
names: Similarity
messages: Belongs to the GppA/Ppx family. GppA subfamily.
messages: Catalyzes the conversion of pppGpp to ppGpp. Guanosine pentaphosphate (pppGpp) is a cytoplasmic signaling molecule which together with ppGpp controls the 'stringent response', an adaptive process that allows bacteria to respond to amino acid starvation, resulting in the coordinated regulation of numerous cellular activities.

230089:VY86 RS03625
gene id: 230089:VY86_RS03625
uniprot id: A0A0F7LKL7
names: Subcellular Location Annotation
messages: Membrane

230089:VY86 RS16150
gene id: 230089:VY86_RS16150
uniprot id: A0A0F7LQ06
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Membrane

230089:VY86 RS01550
gene id: 230089:VY86_RS01550
uniprot id: A0A0F7LK94
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein uS19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein uS19.

230089:VY86 RS04055
gene id: 230089:VY86_RS04055
uniprot id: A0A0F7LJ23
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

230089:VY86 RS04105
gene id: 230089:VY86_RS04105
uniprot id: A0A0F7LKT9
names: Similarity
messages: Belongs to the bleomycin resistance protein family.

230089:VY86 RS12965
gene id: 230089:VY86_RS12965
uniprot id: A0A0F7LLQ9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PanZ/PanM family.
messages: Controls both the activation and catalytic activity of PanD in a coenzyme A (CoA)-dependent fashion.
messages: Interacts with PanD in the presence of CoA.

230089:VY86 RS12665
gene id: 230089:VY86_RS12665
uniprot id: A0A0F7LPZ6
names: Subcellular Location Annotation
messages: Secreted

230089:VY86 RS18455
gene id: 230089:VY86_RS18455
uniprot id: A0A0F7LTD3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YkuD family.
messages: Periplasm

230089:VY86 RS15120
gene id: 230089:VY86_RS15120
uniprot id: A0A0F7LRA9
names: Similarity
messages: Belongs to the ModE family.

230089:VY86 RS08235
gene id: 230089:VY86_RS08235
uniprot id: A0A0F7LNC5
names: Function
names: PTM
names: Similarity
messages: Acetylated. Deacetylation by the SIR2-homolog deacetylase activates the enzyme.
messages: Belongs to the ATP-dependent AMP-binding enzyme family.
messages: Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. Acs undergoes a two-step reaction. In the first half reaction, Acs combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.
messages: Enables the cell to use acetate during aerobic growth to generate energy via the TCA cycle, and biosynthetic compounds via the glyoxylate shunt. Acetylates CheY, the response regulator involved in flagellar movement and chemotaxis.

230089:VY86 RS07500
gene id: 230089:VY86_RS07500
uniprot id: A0A0F7LMC5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CpxP/Spy family.
messages: Periplasm

230089:VY86 RS13530
gene id: 230089:VY86_RS13530
uniprot id: A0A0F7LQP1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsY family.
messages: Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
messages: Cell membrane
messages: Probably interacts with PlsX.

230089:VY86 RS00045
gene id: 230089:VY86_RS00045
uniprot id: A0A0F7LKF9
names: Similarity
messages: Belongs to the VgrG protein family.

230089:VY86 RS19000
gene id: 230089:VY86_RS19000
uniprot id: A0A0F7LVC9
names: Similarity
messages: Belongs to the UPF0263 family.

230089:VY86 RS04555
gene id: 230089:VY86_RS04555
uniprot id: A0A0F7LL17
names: Subcellular Location Annotation
messages: Membrane

230089:VY86 RS10900
gene id: 230089:VY86_RS10900
uniprot id: A0A0F7LPI6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PNP/UDP phosphorylase family.
messages: Catalyzes the reversible phosphorylytic cleavage of uridine to uracil and ribose-1-phosphate.
messages: Cytoplasm

230089:VY86 RS15820
gene id: 230089:VY86_RS15820
uniprot id: A0A0F7LRX4
names: Subcellular Location Annotation
messages: Membrane

230089:VY86 RS06700
gene id: 230089:VY86_RS06700
uniprot id: A0A0F7LMS0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

230089:VY86 RS06265
gene id: 230089:VY86_RS06265
uniprot id: A0A0F7LIS4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the band 7/mec-2 family. HflK subfamily.
messages: HflC and HflK could encode or regulate a protease.
messages: HflC and HflK may interact to form a multimeric complex.
messages: Membrane

230089:VY86 RS18790
gene id: 230089:VY86_RS18790
uniprot id: A0A0F7LT88
names: Cofactor
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.
messages: Probably binds two magnesium or manganese ions per subunit.

230089:VY86 RS15435
gene id: 230089:VY86_RS15435
uniprot id: A0A0F7LMN4
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dCTP deaminase family.
messages: Catalyzes the deamination of dCTP to dUTP.
messages: Homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

230089:VY86 RS17110
gene id: 230089:VY86_RS17110
uniprot id: A0A0F7LVH6
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

230089:VY86 RS08840
gene id: 230089:VY86_RS08840
uniprot id: A0A0F7LVA2
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Uronate isomerase family.

230089:VY86 RS06205
gene id: 230089:VY86_RS06205
uniprot id: S4WDN1
names: Similarity
messages: Belongs to the DDAH family.

230089:VY86 RS07900
gene id: 230089:VY86_RS07900
uniprot id: A0A0F7LL05
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.

230089:VY86 RS21275
gene id: 230089:VY86_RS21275
uniprot id: A0A0F7LS82
names: Similarity
messages: Belongs to the transposase 11 family.

230089:VY86 RS17310
gene id: 230089:VY86_RS17310
uniprot id: A0A0F7LSR1
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

230089:VY86 RS00735
gene id: 230089:VY86_RS00735
uniprot id: A0A0F7LJP0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

230089:VY86 RS18170
gene id: 230089:VY86_RS18170
uniprot id: A0A0F7LNW7
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

230089:VY86 RS03525
gene id: 230089:VY86_RS03525
uniprot id: A0A0F7LKY5
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.
messages: In the N-terminal section; belongs to the transposase 2 family.

230089:VY86 RS11935
gene id: 230089:VY86_RS11935
uniprot id: A0A0F7LL88
names: Similarity
messages: Belongs to the YkuD family.

230089:VY86 RS02185
gene id: 230089:VY86_RS02185
uniprot id: A0A0F7LKC7
names: Similarity
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.

230089:VY86 RS04915
gene id: 230089:VY86_RS04915
uniprot id: A0A0F7LI51
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

230089:VY86 RS17265
gene id: 230089:VY86_RS17265
uniprot id: A0A0F7LVB1
names: Subcellular Location Annotation
messages: Cell inner membrane

230089:VY86 RS05840
gene id: 230089:VY86_RS05840
uniprot id: A0A0F7LM12
names: Similarity
messages: Belongs to the transposase 11 family.

230089:VY86 RS05910
gene id: 230089:VY86_RS05910
uniprot id: A0A0F7LM90
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

230089:VY86 RS02250
gene id: 230089:VY86_RS02250
uniprot id: A0A0F7LGR0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SctE/SipB/YopB family.
messages: Host membrane

230089:VY86 RS04295
gene id: 230089:VY86_RS04295
uniprot id: A0A0F7LHK8
names: Similarity
messages: Belongs to the transposase 11 family.

230089:VY86 RS09520
gene id: 230089:VY86_RS09520
uniprot id: A0A0F7LK96
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

230089:VY86 RS07580
gene id: 230089:VY86_RS07580
uniprot id: A0A0F7LJF0
names: Similarity
messages: Belongs to the polysaccharide synthase family.

230089:VY86 RS17015
gene id: 230089:VY86_RS17015
uniprot id: A0A0F7LS67
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

230089:VY86 RS00840
gene id: 230089:VY86_RS00840
uniprot id: A0A0F7LJR3
names: Cofactor
names: Function
messages: Binds 1 [2Fe-2S] cluster.
messages: Regulates the transcription of several operons and genes involved in the biogenesis of Fe-S clusters and Fe-S-containing proteins.

230089:VY86 RS17160
gene id: 230089:VY86_RS17160
uniprot id: A0A0F7LQE8
names: Similarity
names: Subunit
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.

230089:VY86 RS20265
gene id: 230089:VY86_RS20265
uniprot id: A0A0F7LRM8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MinC family.
messages: Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization.
messages: Interacts with MinD and FtsZ.

230089:VY86 RS13525
gene id: 230089:VY86_RS13525
uniprot id: A0A0F7LNS8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

230089:VY86 RS05815
gene id: 230089:VY86_RS05815
uniprot id: A0A0F7LM07
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the binding-protein-dependent transport system permease family. MalFG subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Part of the ABC transporter complex MalEFGK involved in maltose/maltodextrin import. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (MalK), two transmembrane proteins (MalG and MalF) and a solute-binding protein (MalE).

230089:VY86 RS05520
gene id: 230089:VY86_RS05520
uniprot id: A0A0F7LLF8
names: Function
names: Subunit
messages: Homotetramer.
messages: Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.

230089:VY86 RS08485
gene id: 230089:VY86_RS08485
uniprot id: A0A0F7LND6
names: Function
names: Similarity
messages: Belongs to the cyanase family.
messages: Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide.

230089:VY86 RS08765
gene id: 230089:VY86_RS08765
uniprot id: A0A0F7LNH3
names: Similarity
messages: Belongs to the amidinotransferase family.

230089:VY86 RS11840
gene id: 230089:VY86_RS11840
uniprot id: A0A0F7LJK6
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

230089:VY86 RS02320
gene id: 230089:VY86_RS02320
uniprot id: A0A0F7LKJ0
names: Similarity
messages: Belongs to the FliN/MopA/SpaO family.

230089:VY86 RS07220
gene id: 230089:VY86_RS07220
uniprot id: A0A0F7LM89
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic sulfate-binding protein family.
messages: Periplasm

230089:VY86 RS13565
gene id: 230089:VY86_RS13565
uniprot id: A0A0F7LQV1
names: Function
names: Similarity
names: Subunit
messages: Catalyzes the ADP transfer from ATP to D-glycero-beta-D-manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose.
messages: Catalyzes the phosphorylation of D-glycero-D-manno-heptose 7-phosphate at the C-1 position to selectively form D-glycero-beta-D-manno-heptose-1,7-bisphosphate.
messages: Homodimer.
messages: In the C-terminal section; belongs to the cytidylyltransferase family.
messages: In the N-terminal section; belongs to the carbohydrate kinase PfkB family.

230089:VY86 RS06630
gene id: 230089:VY86_RS06630
uniprot id: A0A0F7LLY4
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

230089:VY86 RS17120
gene id: 230089:VY86_RS17120
uniprot id: A0A0F7LSP2
names: Function
names: Similarity
messages: Belongs to the DUF177 domain family.
messages: Plays a role in synthesis, processing and/or stability of 23S rRNA.

230089:VY86 RS06780
gene id: 230089:VY86_RS06780
uniprot id: A0A0F7LMT1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SUA5 family. TsaC subfamily.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Catalyzes the conversion of L-threonine, HCO(3)(-)/CO(2) and ATP to give threonylcarbamoyl-AMP (TC-AMP) as the acyladenylate intermediate, with the release of diphosphate.

230089:VY86 RS02820
gene id: 230089:VY86_RS02820
uniprot id: A0A0F7LKL4
names: Subcellular Location Annotation
messages: Membrane

230089:VY86 RS19455
gene id: 230089:VY86_RS19455
uniprot id: A0A0F7LRE9
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

230089:VY86 RS00835
gene id: 230089:VY86_RS00835
uniprot id: A0A0F7LHI9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.
messages: Cytoplasm
messages: Homodimer. Forms a heterotetramer with IscU, interacts with other sulfur acceptors.
messages: Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins.

230089:VY86 RS16300
gene id: 230089:VY86_RS16300
uniprot id: A0A0F7LVH9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the AB hydrolase superfamily. MenH family.
messages: Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC).
messages: Monomer.

230089:VY86 RS07135
gene id: 230089:VY86_RS07135
uniprot id: A0A0F7LMU7
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

230089:VY86 RS01655
gene id: 230089:VY86_RS01655
uniprot id: A0A0F7LKB2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. XGPT subfamily.
messages: Cell membrane
messages: Homotetramer.
messages: Purine salvage pathway enzyme that catalyzes the transfer of the ribosyl-5-phosphate group from 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to the N9 position of the 6-oxopurines guanine and xanthine to form the corresponding ribonucleotides GMP (guanosine 5'-monophosphate) and XMP (xanthosine 5'-monophosphate), with the release of PPi. To a lesser extent, also acts on hypoxanthine.

230089:VY86 RS10965
gene id: 230089:VY86_RS10965
uniprot id: A0A0F7LKU4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UbiD family.
messages: Binds 1 prenylated FMN (prenyl-FMN) per subunit.
messages: Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis.
messages: Cell membrane
messages: Homohexamer.

230089:VY86 RS10920
gene id: 230089:VY86_RS10920
uniprot id: A0A0F7LMI3
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2).

230089:VY86 RS18565
gene id: 230089:VY86_RS18565
uniprot id: A0A0F7LPA8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the pyridoxamine 5'-phosphate oxidase family.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
messages: Homodimer.

230089:VY86 RS03840
gene id: 230089:VY86_RS03840
uniprot id: A0A0F7LIY4
names: Subcellular Location Annotation
messages: Cell inner membrane

230089:VY86 RS19930
gene id: 230089:VY86_RS19930
uniprot id: A0A0F7LU09
names: Similarity
messages: Belongs to the UPF0482 family.

230089:VY86 RS12840
gene id: 230089:VY86_RS12840
uniprot id: A0A0F7LQJ9
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Alleviates ribosome stalling that occurs when 3 or more consecutive Pro residues or the sequence PPG is present in a protein, possibly by augmenting the peptidyl transferase activity of the ribosome. Modification of Lys-34 is required for alleviation.
messages: May be beta-lysylated on the epsilon-amino group of Lys-34 by the combined action of EpmA and EpmB, and then hydroxylated on the C5 position of the same residue by EpmC (if this protein is present). Lysylation is critical for the stimulatory effect of EF-P on peptide-bond formation. The lysylation moiety may extend toward the peptidyltransferase center and stabilize the terminal 3-CCA end of the tRNA. Hydroxylation of the C5 position on Lys-34 may allow additional potential stabilizing hydrogen-bond interactions with the P-tRNA.

230089:VY86 RS08355
gene id: 230089:VY86_RS08355
uniprot id: A0A0F7LL48
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial secretin family. PilQ subfamily.
messages: Cell outer membrane
messages: Membrane

230089:VY86 RS05570
gene id: 230089:VY86_RS05570
uniprot id: A0A0F7LM27
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UbiC family.
messages: Cytoplasm
messages: Monomer.
messages: Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4-hydroxybenzoate (4HB) for the ubiquinone pathway.

230089:VY86 RS05745
gene id: 230089:VY86_RS05745
uniprot id: A0A0F7LLI6
names: Subcellular Location Annotation
messages: Membrane

230089:VY86 RS01080
gene id: 230089:VY86_RS01080
uniprot id: A0A0F7LG85
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

230089:VY86 RS04985
gene id: 230089:VY86_RS04985
uniprot id: A0A0F7LJJ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetate uptake transporter (AceTr) (TC 2.A.96) family.
messages: Membrane

230089:VY86 RS19995
gene id: 230089:VY86_RS19995
uniprot id: A0A0F7LRK3
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

230089:VY86 RS22010
gene id: 230089:VY86_RS22010
uniprot id: A0A0F7LK93
names: Similarity
messages: Belongs to the transposase 11 family.

230089:VY86 RS07055
gene id: 230089:VY86_RS07055
uniprot id: A0A0F7LKG5
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Homodimer.
messages: Represses the transcription of fabB, involved in unsaturated fatty acid (UFA) biosynthesis. By controlling UFA production, FabR directly influences the physical properties of the membrane bilayer.

230089:VY86 RS14795
gene id: 230089:VY86_RS14795
uniprot id: A0A0F7LMC4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MutH family.
messages: Cytoplasm
messages: Sequence-specific endonuclease that cleaves unmethylated GATC sequences. It is involved in DNA mismatch repair.

230089:VY86 RS05925
gene id: 230089:VY86_RS05925
uniprot id: A0A0F7LJX0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

230089:VY86 RS06165
gene id: 230089:VY86_RS06165
uniprot id: A0A0F7LLM6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MobA family.
messages: Cytoplasm
messages: Monomer.
messages: The N-terminal domain determines nucleotide recognition and specific binding, while the C-terminal domain determines the specific binding to the target protein.
messages: Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor.

230089:VY86 RS01085
gene id: 230089:VY86_RS01085
uniprot id: A0A0F7LHM3
names: Subcellular Location Annotation
messages: Membrane
messages: Secreted
messages: host cytosol

230089:VY86 RS10375
gene id: 230089:VY86_RS10375
uniprot id: A0A0F7LM54
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Component of the RNA degradosome, which is a multiprotein complex involved in RNA processing and mRNA degradation.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

230089:VY86 RS21655
gene id: 230089:VY86_RS21655
uniprot id: A0A0F7LVM0
names: Similarity
messages: Belongs to the site-specific recombinase resolvase family.

230089:VY86 RS04080
gene id: 230089:VY86_RS04080
uniprot id: A0A0F7LJ24
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the formate dehydrogenase gamma subunit family.
messages: Membrane

230089:VY86 RS17915
gene id: 230089:VY86_RS17915
uniprot id: A0A0F7LT33
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M20A family. DapE subfamily.
messages: Binds 2 Zn(2+) or Co(2+) ions per subunit.
messages: Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls.
messages: Homodimer.

230089:VY86 RS12875
gene id: 230089:VY86_RS12875
uniprot id: A0A0F7LQK1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. EpmA subfamily.
messages: Homodimer.
messages: With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta-lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P.

230089:VY86 RS01495
gene id: 230089:VY86_RS01495
uniprot id: A0A0F7LUS8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamD family.
messages: Cell outer membrane
messages: Part of the Bam complex, which is composed of the outer membrane protein BamA, and four lipoproteins BamB, BamC, BamD and BamE.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. Constitutes, with BamA, the core component of the assembly machinery.

230089:VY86 RS06450
gene id: 230089:VY86_RS06450
uniprot id: A0A0F7LMJ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Mediates influx of magnesium ions.
messages: Membrane

230089:VY86 RS17540
gene id: 230089:VY86_RS17540
uniprot id: A0A0F7LSI9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48 family. BepA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Functions as both a chaperone and a metalloprotease. Maintains the integrity of the outer membrane by promoting either the assembly or the elimination of outer membrane proteins, depending on their folding state.
messages: Periplasm

230089:VY86 RS05930
gene id: 230089:VY86_RS05930
uniprot id: A0A0F7LM31
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

230089:VY86 RS15010
gene id: 230089:VY86_RS15010
uniprot id: A0A0F7LPD2
names: Subcellular Location Annotation
messages: Membrane

230089:VY86 RS06930
gene id: 230089:VY86_RS06930
uniprot id: A0A0F7LMJ6
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

230089:VY86 RS15015
gene id: 230089:VY86_RS15015
uniprot id: A0A0F7LRI3
names: Function
names: Similarity
messages: Belongs to the NadC/ModD family.
messages: Involved in the catabolism of quinolinic acid (QA).

230089:VY86 RS13340
gene id: 230089:VY86_RS13340
uniprot id: A0A0F7LQ70
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

230089:VY86 RS05950
gene id: 230089:VY86_RS05950
uniprot id: A0A0F7LJY0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

230089:VY86 RS06925
gene id: 230089:VY86_RS06925
uniprot id: A0A0F7LKD1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

230089:VY86 RS18705
gene id: 230089:VY86_RS18705
uniprot id: A0A0F7LT83
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

230089:VY86 RS14890
gene id: 230089:VY86_RS14890
uniprot id: A0A0F7LRQ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

230089:VY86 RS12895
gene id: 230089:VY86_RS12895
uniprot id: A0A0F7LQB4
names: Cofactor
names: Similarity
messages: Belongs to the iron-containing alcohol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.

230089:VY86 RS10370
gene id: 230089:VY86_RS10370
uniprot id: A0A0F7LKI6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

230089:VY86 RS08565
gene id: 230089:VY86_RS08565
uniprot id: A0A0F7LJU0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal stress protein B family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

230089:VY86 RS17170
gene id: 230089:VY86_RS17170
uniprot id: A0A0F7LSP9
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

230089:VY86 RS01270
gene id: 230089:VY86_RS01270
uniprot id: A0A0F7LGA9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

230089:VY86 RS07795
gene id: 230089:VY86_RS07795
uniprot id: A0A0F7LN57
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase group 1 family.
messages: Cell membrane
messages: Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP-Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A.

230089:VY86 RS02560
gene id: 230089:VY86_RS02560
uniprot id: A0A0F7LI75
names: Cofactor
messages: Binds 1 phosphopantetheine covalently.

230089:VY86 RS08340
gene id: 230089:VY86_RS08340
uniprot id: A0A0F7LND0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DamX family.
messages: Cell inner membrane
messages: Non-essential cell division protein.
messages: The SPOR domain binds septal peptidoglycans and is required to target DamX to the septal ring.

230089:VY86 RS15600
gene id: 230089:VY86_RS15600
uniprot id: A0A0F7LPS8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 3 family.
messages: Periplasm

230089:VY86 RS17950
gene id: 230089:VY86_RS17950
uniprot id: A0A0F7LT25
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

230089:VY86 RS14440
gene id: 230089:VY86_RS14440
uniprot id: A0A0F7LQS3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Two distinct, membrane-bound, FAD-containing enzymes are responsible for the catalysis of fumarate and succinate interconversion; the fumarate reductase is used in anaerobic growth, and the succinate dehydrogenase is used in aerobic growth.

230089:VY86 RS01175
gene id: 230089:VY86_RS01175
uniprot id: A0A0F7LK46
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

230089:VY86 RS00740
gene id: 230089:VY86_RS00740
uniprot id: A0A0F7LK01
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

230089:VY86 RS12865
gene id: 230089:VY86_RS12865
uniprot id: A0A0F7LQB0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Part of an enzyme complex containing four subunits: a flavoprotein (FrdA), an iron-sulfur protein (FrdB), and two hydrophobic anchor proteins (FrdC and FrdD).

230089:VY86 RS04895
gene id: 230089:VY86_RS04895
uniprot id: A0A0F7LJI0
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

230089:VY86 RS07990
gene id: 230089:VY86_RS07990
uniprot id: A0A0F7LN87
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

230089:VY86 RS02645
gene id: 230089:VY86_RS02645
uniprot id: A0A0F7LJX9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family.
messages: Binds 1 Mg(2+) ion per subunit. Can also utilize other divalent metal cations, such as Ca(2+), Mn(2+) and Co(2+).
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
messages: Homodimer.

230089:VY86 RS16775
gene id: 230089:VY86_RS16775
uniprot id: A0A0F7LN48
names: Function
names: Similarity
messages: Belongs to the CobU/CobP family.
messages: Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate.

230089:VY86 RS16080
gene id: 230089:VY86_RS16080
uniprot id: A0A0F7LS05
names: Similarity
messages: Belongs to the myoviridae tail sheath protein family.

230089:VY86 RS12030
gene id: 230089:VY86_RS12030
uniprot id: A0A0F7LPX0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

230089:VY86 RS13375
gene id: 230089:VY86_RS13375
uniprot id: A0A0F7LNS0
names: Function
names: Similarity
messages: Belongs to the peptidase C56 family.
messages: Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate.

230089:VY86 RS00100
gene id: 230089:VY86_RS00100
uniprot id: A0A0F7LJM1
names: Subcellular Location Annotation
messages: Membrane

230089:VY86 RS00560
gene id: 230089:VY86_RS00560
uniprot id: A0A0F7LJM0
names: Similarity
messages: Belongs to the MlaA family.

230089:VY86 RS19675
gene id: 230089:VY86_RS19675
uniprot id: A0A0F7LRG6
names: Similarity
messages: Belongs to the VgrG protein family.

230089:VY86 RS21830
gene id: 230089:VY86_RS21830
uniprot id: A0A0F7LVM2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MotA family.
messages: Membrane

230089:VY86 RS12680
gene id: 230089:VY86_RS12680
uniprot id: A0A0F7LK93
names: Similarity
messages: Belongs to the transposase 11 family.

230089:VY86 RS08010
gene id: 230089:VY86_RS08010
uniprot id: A0A0F7LL29
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Binds two Mg(2+) per subunit. The magnesium ions form salt bridges with both the protein and the DNA. Can also accept other divalent metal cations, such as Mn(2+) or Ca(2+).
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

230089:VY86 RS05005
gene id: 230089:VY86_RS05005
uniprot id: A0A0F7LL89
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. GalK subfamily.
messages: Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P).
messages: Cytoplasm

230089:VY86 RS17565
gene id: 230089:VY86_RS17565
uniprot id: A0A0F7LSJ2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamC family.
messages: Cell outer membrane
messages: Part of the Bam complex, which is composed of the outer membrane protein BamA, and four lipoproteins BamB, BamC, BamD and BamE.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

230089:VY86 RS14505
gene id: 230089:VY86_RS14505
uniprot id: A0A0F7LQS9
names: Similarity
messages: Belongs to the UbiH/COQ6 family.

230089:VY86 RS01390
gene id: 230089:VY86_RS01390
uniprot id: A0A0F7LJD7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.
messages: Binds 2 iron ions per subunit.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.
messages: Tetramer of two alpha and two beta subunits.

230089:VY86 RS02490
gene id: 230089:VY86_RS02490
uniprot id: A0A0F7LKH8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.

230089:VY86 RS18945
gene id: 230089:VY86_RS18945
uniprot id: A0A0F7LR95
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone-like protein H-NS family.
messages: nucleoid

230089:VY86 RS16760
gene id: 230089:VY86_RS16760
uniprot id: A0A0F7LS74
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CbiQ family.
messages: Membrane

230089:VY86 RS15825
gene id: 230089:VY86_RS15825
uniprot id: A0A0F7LS51
names: Subcellular Location Annotation
messages: Membrane

230089:VY86 RS10475
gene id: 230089:VY86_RS10475
uniprot id: A0A0F7LPC4
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

230089:VY86 RS20300
gene id: 230089:VY86_RS20300
uniprot id: A0A0F7LU65
names: Similarity
messages: Belongs to the KAE1 / TsaD family. TsaB subfamily.

230089:VY86 RS02915
gene id: 230089:VY86_RS02915
uniprot id: A0A0F7LIF1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

230089:VY86 RS16925
gene id: 230089:VY86_RS16925
uniprot id: A0A0F7LSK5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YejK family.
messages: nucleoid

230089:VY86 RS18145
gene id: 230089:VY86_RS18145
uniprot id: A0A0F7LNW3
names: Similarity
messages: Belongs to the bacterial solute-binding protein 9 family.

230089:VY86 RS09070
gene id: 230089:VY86_RS09070
uniprot id: A0A0F7LK11
names: Similarity
names: Subunit
messages: Belongs to the threonine aldolase family.
messages: Homotetramer.

230089:VY86 RS20330
gene id: 230089:VY86_RS20330
uniprot id: A0A0F7LU67
names: Similarity
messages: Belongs to the HipA Ser/Thr kinase family.

230089:VY86 RS00830
gene id: 230089:VY86_RS00830
uniprot id: A0A0F7LG44
names: Function
names: Similarity
messages: A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters.
messages: Belongs to the NifU family.

230089:VY86 RS16700
gene id: 230089:VY86_RS16700
uniprot id: A0A0F7LN21
names: Similarity
messages: Belongs to the CobH/CbiC family.

230089:VY86 RS07660
gene id: 230089:VY86_RS07660
uniprot id: A0A0F7LMF3
names: Similarity
messages: Belongs to the polysaccharide synthase family.

230089:VY86 RS14955
gene id: 230089:VY86_RS14955
uniprot id: A0A0F7LPB2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

230089:VY86 RS20955
gene id: 230089:VY86_RS20955
uniprot id: A0A0F7LUD2
names: Caution
names: Cofactor
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Phosphotriesterase family.
messages: Binds 2 divalent metal cations per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

230089:VY86 RS15530
gene id: 230089:VY86_RS15530
uniprot id: A0A0F7LS22
names: Similarity
messages: Belongs to the GST superfamily.

230089:VY86 RS18090
gene id: 230089:VY86_RS18090
uniprot id: A0A0F7LNV5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ProQ family.
messages: Cytoplasm
messages: RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities. May regulate ProP activity through an RNA-based, post-transcriptional mechanism.

230089:VY86 RS19350
gene id: 230089:VY86_RS19350
uniprot id: A0A0F7LTF6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfC subfamily.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell inner membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

230089:VY86 RS21885
gene id: 230089:VY86_RS21885
uniprot id: A0A0F7LUL2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
messages: Homodimer.

230089:VY86 RS17295
gene id: 230089:VY86_RS17295
uniprot id: A0A0F7LNC4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HflD family.
messages: Cell membrane
messages: Cytoplasm

230089:VY86 RS16145
gene id: 230089:VY86_RS16145
uniprot id: A0A0F7LMT8
names: Similarity
messages: Belongs to the GSP E family.

230089:VY86 RS17035
gene id: 230089:VY86_RS17035
uniprot id: A0A0F7LSN2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the quinone-dependent D-lactate dehydrogenase family.
messages: Catalyzes the oxidation of D-lactate to pyruvate.
messages: Cell inner membrane

230089:VY86 RS05365
gene id: 230089:VY86_RS05365
uniprot id: A0A0F7LUY0
names: Similarity
names: Subunit
messages: Homotetramer.
messages: In the C-terminal section; belongs to the homoserine dehydrogenase family.
messages: In the N-terminal section; belongs to the aspartokinase family.

230089:VY86 RS14435
gene id: 230089:VY86_RS14435
uniprot id: A0A0F7LRD8
names: Cofactor
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Binds 1 [3Fe-4S] cluster.
messages: Binds 1 [4Fe-4S] cluster.

230089:VY86 RS14860
gene id: 230089:VY86_RS14860
uniprot id: A0A0F7LRF1
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

230089:VY86 RS02065
gene id: 230089:VY86_RS02065
uniprot id: A0A0F7LJM9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RseB family.
messages: Periplasm

230089:VY86 RS00680
gene id: 230089:VY86_RS00680
uniprot id: A0A0F7LJN4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Membrane
messages: Part of the ABC transporter complex (TC 3.A.1.6.1) involved in sulfate/thiosulfate import.
messages: Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (CysA), two transmembrane proteins (CysT and CysW) and a solute-binding protein (CysP).

230089:VY86 RS15750
gene id: 230089:VY86_RS15750
uniprot id: A0A0F7LPU8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FNT transporter (TC 2.A.44) family.
messages: Membrane

230089:VY86 RS06635
gene id: 230089:VY86_RS06635
uniprot id: A0A0F7LIX0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

230089:VY86 RS18130
gene id: 230089:VY86_RS18130
uniprot id: A0A0F7LSU2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

230089:VY86 RS21215
gene id: 230089:VY86_RS21215
uniprot id: A0A0F7LQJ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliG family.
messages: Cell inner membrane
messages: FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
messages: Membrane

230089:VY86 RS06880
gene id: 230089:VY86_RS06880
uniprot id: A0A0F7LMJ4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

230089:VY86 RS06625
gene id: 230089:VY86_RS06625
uniprot id: A0A0F7LMM1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. UvrD subfamily.
messages: Homodimer.
messages: Rep helicase is a single-stranded DNA-dependent ATPase involved in DNA replication; it can initiate unwinding at a nick in the DNA. It binds to the single-stranded DNA and acts in a progressive fashion along the DNA in the 3' to 5' direction.

230089:VY86 RS05990
gene id: 230089:VY86_RS05990
uniprot id: A0A0F7LLL3
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

230089:VY86 RS06180
gene id: 230089:VY86_RS06180
uniprot id: A0A0F7LM87
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

230089:VY86 RS07175
gene id: 230089:VY86_RS07175
uniprot id: A0A0F7LJ48
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MenA family. Type 1 subfamily.
messages: Cell membrane
messages: Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK).
messages: Membrane

230089:VY86 RS14045
gene id: 230089:VY86_RS14045
uniprot id: A0A0F7LR37
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TonB family.
messages: Cell inner membrane
messages: Homodimer. Forms a complex with the accessory proteins ExbB and ExbD.
messages: Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins.

230089:VY86 RS13305
gene id: 230089:VY86_RS13305
uniprot id: A0A0F7LQH3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm

230089:VY86 RS19045
gene id: 230089:VY86_RS19045
uniprot id: A0A0F7LTA7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0259 family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

230089:VY86 RS15135
gene id: 230089:VY86_RS15135
uniprot id: A0A0F7LRT6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane.

230089:VY86 RS10505
gene id: 230089:VY86_RS10505
uniprot id: A0A0F7LPD0
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.
messages: In the N-terminal section; belongs to the transposase 2 family.

230089:VY86 RS16225
gene id: 230089:VY86_RS16225
uniprot id: A0A0F7LRQ5
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

230089:VY86 RS16955
gene id: 230089:VY86_RS16955
uniprot id: A0A0F7LS56
names: Similarity
messages: Belongs to the peptidase C40 family.

230089:VY86 RS04310
gene id: 230089:VY86_RS04310
uniprot id: A0A0F7LS82
names: Similarity
messages: Belongs to the transposase 11 family.

230089:VY86 RS15410
gene id: 230089:VY86_RS15410
uniprot id: A0A0F7LMN3
names: Subcellular Location Annotation
messages: Membrane

230089:VY86 RS06915
gene id: 230089:VY86_RS06915
uniprot id: A0A0F7LM55
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

230089:VY86 RS20750
gene id: 230089:VY86_RS20750
uniprot id: A0A0F7LUB2
names: Similarity
messages: Belongs to the proline racemase family.

230089:VY86 RS04425
gene id: 230089:VY86_RS04425
uniprot id: A0A0F7LLD7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

230089:VY86 RS06840
gene id: 230089:VY86_RS06840
uniprot id: A0A0F7LJ13
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

230089:VY86 RS20705
gene id: 230089:VY86_RS20705
uniprot id: A0A0F7LQ91
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

230089:VY86 RS16920
gene id: 230089:VY86_RS16920
uniprot id: A0A0F7LS97
names: Similarity
messages: Belongs to the UPF0352 family.

230089:VY86 RS08190
gene id: 230089:VY86_RS08190
uniprot id: A0A0F7LNB7
names: Subcellular Location Annotation
messages: Membrane

230089:VY86 RS01185
gene id: 230089:VY86_RS01185
uniprot id: A0A0F7LGA3
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Allosterically activated by N-acetylglucosamine 6-phosphate (GlcNAc6P).
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily.
messages: Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.
messages: Homohexamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

230089:VY86 RS20540
gene id: 230089:VY86_RS20540
uniprot id: A0A0F7LU30
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. DHA1 family. MdtH (TC 2.A.1.2.21) subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

230089:VY86 RS21910
gene id: 230089:VY86_RS21910
uniprot id: A0A0F7LUT1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LpxL/LpxM/LpxP family.
messages: Catalyzes the transfer of an acyl chain from an acyl-[acyl-carrier-protein] (ACP) to a Kdo(2)-lipid IV(A) to form a Kdo(2)-(acyl)-lipid IV(A).
messages: Cell inner membrane

230089:VY86 RS20340
gene id: 230089:VY86_RS20340
uniprot id: A0A0F7LQ43
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family. MdtJ subfamily.
messages: Catalyzes the excretion of spermidine.
messages: Cell membrane
messages: Forms a complex with MdtI.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

230089:VY86 RS02375
gene id: 230089:VY86_RS02375
uniprot id: A0A0F7LJU1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SctF family.
messages: Cell surface
messages: Secreted

230089:VY86 RS04870
gene id: 230089:VY86_RS04870
uniprot id: A0A0F7LJH7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

230089:VY86 RS15870
gene id: 230089:VY86_RS15870
uniprot id: A0A0F7LRY2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family. MukB subfamily.
messages: Homodimerization via its hinge domain. Binds to DNA via its C-terminal region. Interacts, and probably forms a ternary complex, with MukE and MukF via its C-terminal region. The complex formation is stimulated by calcium or magnesium. Interacts with tubulin-related protein FtsZ.
messages: Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division.
messages: The hinge domain, which separates the large intramolecular coiled coil regions, allows the homodimerization, forming a V-shaped homodimer.
messages: nucleoid

230089:VY86 RS19410
gene id: 230089:VY86_RS19410
uniprot id: A0A0F7LPN7
names: Similarity
messages: Belongs to the site-specific recombinase resolvase family.

230089:VY86 RS17165
gene id: 230089:VY86_RS17165
uniprot id: A0A0F7LSB9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transglycosylase MltG family.
messages: Cell inner membrane
messages: Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.

230089:VY86 RS21450
gene id: 230089:VY86_RS21450
uniprot id: A0A0F7LUH2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of a number of rings mounted on a central rod.

230089:VY86 RS07080
gene id: 230089:VY86_RS07080
uniprot id: A0A0F7LKH0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm
messages: Homodimer.

230089:VY86 RS21465
gene id: 230089:VY86_RS21465
uniprot id: A0A0F7LUL3
names: Function
names: Similarity
messages: Belongs to the FlgN family.
messages: Required for the efficient initiation of filament assembly.

230089:VY86 RS15875
gene id: 230089:VY86_RS15875
uniprot id: A0A0F7LS58
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

230089:VY86 RS08435
gene id: 230089:VY86_RS08435
uniprot id: A0A0F7LK93
names: Similarity
messages: Belongs to the transposase 11 family.

230089:VY86 RS04845
gene id: 230089:VY86_RS04845
uniprot id: A0A0F7LJG3
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

230089:VY86 RS03135
gene id: 230089:VY86_RS03135
uniprot id: A0A0F7LKU7
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

230089:VY86 RS11905
gene id: 230089:VY86_RS11905
uniprot id: A0A0F7LPC3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrF family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Cell membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway.

230089:VY86 RS06960
gene id: 230089:VY86_RS06960
uniprot id: A0A0F7LMV2
names: Function
names: Similarity
messages: Belongs to the bacterioferritin family.
messages: Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex.

230089:VY86 RS06845
gene id: 230089:VY86_RS06845
uniprot id: A0A0F7LKB0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

230089:VY86 RS21185
gene id: 230089:VY86_RS21185
uniprot id: A0A0F7LUC8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum
messages: Belongs to the FliD family.
messages: Homopentamer.
messages: Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.
messages: Required for the morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.
messages: Secreted

230089:VY86 RS08130
gene id: 230089:VY86_RS08130
uniprot id: A0A0F7LNA3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

230089:VY86 RS09025
gene id: 230089:VY86_RS09025
uniprot id: A0A0F7LNP7
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

230089:VY86 RS00770
gene id: 230089:VY86_RS00770
uniprot id: A0A0F7LJ67
names: Function
names: Similarity
messages: Belongs to the protease inhibitor I39 (alpha-2-macroglobulin) family. Bacterial alpha-2-macroglobulin subfamily.
messages: Protects the bacterial cell from host peptidases.

230089:VY86 RS05395
gene id: 230089:VY86_RS05395
uniprot id: A0A0F7LIB8
names: Similarity
messages: Belongs to the UPF0246 family.

230089:VY86 RS17325
gene id: 230089:VY86_RS17325
uniprot id: A0A0F7LV82
names: Function
names: Similarity
messages: Belongs to the transposase 11 family.
messages: Involved in the transposition of the insertion sequence IS5.

230089:VY86 RS01325
gene id: 230089:VY86_RS01325
uniprot id: A0A0F7LHQ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RlpA family.
messages: Cell membrane
messages: Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides.

230089:VY86 RS13240
gene id: 230089:VY86_RS13240
uniprot id: A0A0F7LLT6
names: Function
names: Similarity
messages: Belongs to the sigma-54 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

230089:VY86 RS20130
gene id: 230089:VY86_RS20130
uniprot id: A0A0F7LRL8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UreE family.
messages: Cytoplasm
messages: Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly.

230089:VY86 RS04880
gene id: 230089:VY86_RS04880
uniprot id: A0A0F7LLR9
names: Function
names: Similarity
messages: Belongs to the Ap4A hydrolase family.
messages: Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP.

230089:VY86 RS08335
gene id: 230089:VY86_RS08335
uniprot id: A0A0F7LNB9
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

230089:VY86 RS18360
gene id: 230089:VY86_RS18360
uniprot id: A0A0F7LTC8
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the thioesterase PaaI family.
messages: Catalyzes the hydrolysis of 1,4-dihydroxy-2-naphthoyl-CoA (DHNA-CoA) to 1,4-dihydroxy-2-naphthoate (DHNA).
messages: Homotetramer. Dimer of dimers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

230089:VY86 RS03080
gene id: 230089:VY86_RS03080
uniprot id: A0A0F7LII3
names: Subcellular Location Annotation
messages: Membrane

230089:VY86 RS01430
gene id: 230089:VY86_RS01430
uniprot id: A0A0F7LK00
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

230089:VY86 RS10350
gene id: 230089:VY86_RS10350
uniprot id: A0A0F7LM52
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

230089:VY86 RS07060
gene id: 230089:VY86_RS07060
uniprot id: A0A0F7LMM2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Conversion of NADPH, generated by peripheral catabolic pathways, to NADH, which can enter the respiratory chain for energy generation.
messages: Cytoplasm

230089:VY86 RS17150
gene id: 230089:VY86_RS17150
uniprot id: A0A0F7LS90
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

230089:VY86 RS14770
gene id: 230089:VY86_RS14770
uniprot id: A0A0F7LMB9
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SprT family.
messages: Binds 1 zinc ion.
messages: Cytoplasm

230089:VY86 RS05960
gene id: 230089:VY86_RS05960
uniprot id: A0A0F7LM95
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

230089:VY86 RS15160
gene id: 230089:VY86_RS15160
uniprot id: A0A0F7LRJ2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily.
messages: Catalyzes the transfer of the alpha-amino group from S-adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only aminotransferase known to utilize SAM as an amino donor.
messages: Cytoplasm
messages: Homodimer.

230089:VY86 RS02085
gene id: 230089:VY86_RS02085
uniprot id: A0A0F7LUU0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. tRNA (adenine-N(6)-)-methyltransferase family.
messages: Cytoplasm
messages: Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC).

230089:VY86 RS10210
gene id: 230089:VY86_RS10210
uniprot id: A0A0F7LM39
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PPase family.
messages: Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
messages: Cytoplasm
messages: Homohexamer.

230089:VY86 RS17105
gene id: 230089:VY86_RS17105
uniprot id: A0A0F7LQE2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase E/G family. RNase E subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per homotetramer.
messages: Cell inner membrane
messages: Component of the RNA degradosome, which is a multiprotein complex involved in RNA processing and mRNA degradation. Within the RNA degradosome, RNase E assembles into a homotetramer formed by a dimer of dimers.
messages: Cytoplasm
messages: Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs.

230089:VY86 RS09340
gene id: 230089:VY86_RS09340
uniprot id: A0A0F7LK81
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

230089:VY86 RS05495
gene id: 230089:VY86_RS05495
uniprot id: A0A0F7LID8
names: Similarity
messages: Belongs to the HicA mRNA interferase family.

230089:VY86 RS02935
gene id: 230089:VY86_RS02935
uniprot id: A0A0F7LH41
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferrochelatase family.
messages: Catalyzes the ferrous insertion into protoporphyrin IX.
messages: Cytoplasm

230089:VY86 RS11105
gene id: 230089:VY86_RS11105
uniprot id: A0A0F7LP11
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the periplasmic pilus chaperone family.
messages: Periplasm

230089:VY86 RS21235
gene id: 230089:VY86_RS21235
uniprot id: A0A0F7LUD3
names: Function
names: Similarity
messages: Belongs to the FliK family.
messages: Controls the length of the flagellar hook.

230089:VY86 RS06875
gene id: 230089:VY86_RS06875
uniprot id: A0A0F7LKB4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

230089:VY86 RS11930
gene id: 230089:VY86_RS11930
uniprot id: A0A0F7LPC8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NqrA family.
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

230089:VY86 RS04885
gene id: 230089:VY86_RS04885
uniprot id: A0A0F7LL70
names: Function
names: Similarity
messages: Belongs to the dihydrofolate reductase family.
messages: Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.

230089:VY86 RS17135
gene id: 230089:VY86_RS17135
uniprot id: A0A0F7LQE4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

230089:VY86 RS13320
gene id: 230089:VY86_RS13320
uniprot id: A0A0F7LLU2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZapG family.
messages: Cell inner membrane
messages: Membrane

230089:VY86 RS16980
gene id: 230089:VY86_RS16980
uniprot id: A0A0F7LSA3
names: Similarity
messages: Belongs to the Nudix hydrolase family.

230089:VY86 RS15265
gene id: 230089:VY86_RS15265
uniprot id: A0A0F7LRV9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DEAD box helicase family. RhlE subfamily.
messages: Cytoplasm
messages: DEAD-box RNA helicase involved in ribosome assembly. Has RNA-dependent ATPase activity and unwinds double-stranded RNA.

230089:VY86 RS00425
gene id: 230089:VY86_RS00425
uniprot id: A0A0F7LJI9
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

230089:VY86 RS00385
gene id: 230089:VY86_RS00385
uniprot id: A0A0F7LG23
names: Function
names: Similarity
messages: Belongs to the folylpolyglutamate synthase family.
messages: Functions in two distinct reactions of the de novo folate biosynthetic pathway. Catalyzes the addition of a glutamate residue to dihydropteroate (7,8-dihydropteroate or H2Pte) to form dihydrofolate (7,8-dihydrofolate monoglutamate or H2Pte-Glu). Also catalyzes successive additions of L-glutamate to tetrahydrofolate or 10-formyltetrahydrofolate or 5,10-methylenetetrahydrofolate, leading to folylpolyglutamate derivatives.

230089:VY86 RS10880
gene id: 230089:VY86_RS10880
uniprot id: A0A0F7LNZ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LysR transcriptional regulatory family.
messages: Cytoplasm

230089:VY86 RS00275
gene id: 230089:VY86_RS00275
uniprot id: A0A0F7LJP3
names: Subcellular Location Annotation
messages: Membrane

230089:VY86 RS01320
gene id: 230089:VY86_RS01320
uniprot id: A0A0F7LGB8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEDS family. MrdB/RodA subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Peptidoglycan polymerase that is essential for cell wall elongation.

230089:VY86 RS13815
gene id: 230089:VY86_RS13815
uniprot id: A0A0F7LR03
names: Function
names: Similarity
messages: Belongs to the non-flavoprotein flavin reductase family. HpaC subfamily.
messages: Catalyzes the reduction of free flavins (FMN, FAD and riboflavin) by NADH. Subsequently, the reduced flavins diffuse to the large HpaB component or to other electron acceptors such as cytochrome c and Fe(3+) ion.

230089:VY86 RS10980
gene id: 230089:VY86_RS10980
uniprot id: A0A0F7LPL2
names: Function
names: Similarity
names: Subunit
messages: Heterotetramer of two alpha chains (FadB) and two beta chains (FadA).
messages: In the C-terminal section; belongs to the 3-hydroxyacyl-CoA dehydrogenase family.
messages: In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family.
messages: Involved in the aerobic and anaerobic degradation of long-chain fatty acids via beta-oxidation cycle. Catalyzes the formation of 3-oxoacyl-CoA from enoyl-CoA via L-3-hydroxyacyl-CoA. It can also use D-3-hydroxyacyl-CoA and cis-3-enoyl-CoA as substrate.

230089:VY86 RS07690
gene id: 230089:VY86_RS07690
uniprot id: A0A0F7LR49
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

230089:VY86 RS20665
gene id: 230089:VY86_RS20665
uniprot id: A0A0F7LUA4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

230089:VY86 RS10530
gene id: 230089:VY86_RS10530
uniprot id: A0A0F7LMC1
names: Similarity
messages: Belongs to the UPF0306 family.

230089:VY86 RS01625
gene id: 230089:VY86_RS01625
uniprot id: A0A0F7LSQ8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. LplT (TC 2.A.1.42) family.
messages: Catalyzes the facilitated diffusion of 2-acyl-glycero-3-phosphoethanolamine (2-acyl-GPE) into the cell.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

230089:VY86 RS06965
gene id: 230089:VY86_RS06965
uniprot id: A0A0F7LM63
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

230089:VY86 RS04585
gene id: 230089:VY86_RS04585
uniprot id: A0A0F7LL21
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.

230089:VY86 RS15005
gene id: 230089:VY86_RS15005
uniprot id: A0A0F7LMG5
names: Similarity
messages: Belongs to the GSP E family.

230089:VY86 RS04860
gene id: 230089:VY86_RS04860
uniprot id: A0A0F7LL66
names: Domain
names: Function
names: Subcellular Location Annotation
messages: Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation.
messages: Periplasm
messages: The PPIase activity resides only in the second parvulin domain. The N-terminal region and the C-terminal tail are necessary and sufficient for the chaperone activity of SurA. The PPIase activity is dispensable for SurA to function as a chaperone. The N-terminal region and the C-terminal tail are also required for porin recognition.

230089:VY86 RS19335
gene id: 230089:VY86_RS19335
uniprot id: A0A0F7LRD7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell inner membrane
messages: Membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

230089:VY86 RS21750
gene id: 230089:VY86_RS21750
uniprot id: A0A0F7LQR4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the porin LamB (TC 1.B.3) family.
messages: Membrane

230089:VY86 RS09305
gene id: 230089:VY86_RS09305
uniprot id: A0A0F7LNZ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the periplasmic pilus chaperone family.
messages: Periplasm

230089:VY86 RS12255
gene id: 230089:VY86_RS12255
uniprot id: A0A0F7LPL0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
messages: Monomer.

230089:VY86 RS10345
gene id: 230089:VY86_RS10345
uniprot id: A0A0F7LV47
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

230089:VY86 RS06590
gene id: 230089:VY86_RS06590
uniprot id: A0A0F7LMG8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.
messages: Catalyzes the reversible epimerization at C-2 of UDP-N-acetylglucosamine (UDP-GlcNAc) and thereby provides bacteria with UDP-N-acetylmannosamine (UDP-ManNAc), the activated donor of ManNAc residues.
messages: Cytoplasm
messages: Homodimer.

230089:VY86 RS10820
gene id: 230089:VY86_RS10820
uniprot id: A0A0F7LKR9
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.

230089:VY86 RS06790
gene id: 230089:VY86_RS06790
uniprot id: A0A0F7LIY9
names: Similarity
messages: Belongs to the DprA/Smf family.

230089:VY86 RS11495
gene id: 230089:VY86_RS11495
uniprot id: A0A0F7LSZ2
names: Similarity
messages: Belongs to the Rpn/YhgA-like nuclease family.

230089:VY86 RS08420
gene id: 230089:VY86_RS08420
uniprot id: A0A0F7LND5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Cytoplasm
messages: Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.
messages: Monomer.

230089:VY86 RS10990
gene id: 230089:VY86_RS10990
uniprot id: A0A0F7LKV1
names: Similarity
messages: Belongs to the IMPACT family.

230089:VY86 RS07095
gene id: 230089:VY86_RS07095
uniprot id: A0A0F7LM72
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PEPCase type 1 family.
messages: Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.
messages: Homotetramer.

230089:VY86 RS19140
gene id: 230089:VY86_RS19140
uniprot id: A0A0F7LRB5
names: Function
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.
messages: Catalyzes the isomerization of citrate to isocitrate via cis-aconitate.

230089:VY86 RS07195
gene id: 230089:VY86_RS07195
uniprot id: A0A0F7LM86
names: Activity Regulation
names: Function
names: Similarity
names: Subunit
messages: Activity of this regulatory enzyme is affected by several metabolites. Allosterically and non-competitively inhibited by fructose 1,6-bisphosphate (FBP) and unphosphorylated phosphocarrier protein EIIA-Glc (III-Glc), an integral component of the bacterial phosphotransferase (PTS) system.
messages: Belongs to the FGGY kinase family.
messages: Homotetramer and homodimer (in equilibrium). Heterodimer with EIIA-Glc. Binds 1 zinc ion per glycerol kinase EIIA-Glc dimer. The zinc ion is important for dimerization.
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.

230089:VY86 RS19145
gene id: 230089:VY86_RS19145
uniprot id: A0A0F7LTD8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase II family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.
messages: Homodimer.

230089:VY86 RS00805
gene id: 230089:VY86_RS00805
uniprot id: A0A0F7LG43
names: Function
names: Similarity
messages: Belongs to the IscX family.
messages: May function as iron donor in the assembly of iron-sulfur clusters.

230089:VY86 RS16210
gene id: 230089:VY86_RS16210
uniprot id: A0A0F7LQ10
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 3 family.
messages: Cell membrane
messages: NDH-1 is composed of 13 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

230089:VY86 RS07870
gene id: 230089:VY86_RS07870
uniprot id: A0A0F7LJJ6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.

230089:VY86 RS00355
gene id: 230089:VY86_RS00355
uniprot id: A0A0F7LG20
names: Similarity
messages: Belongs to the GST superfamily.

230089:VY86 RS08900
gene id: 230089:VY86_RS08900
uniprot id: A0A0F7LNI8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AB hydrolase superfamily. Carboxylesterase BioH family.
messages: Cytoplasm
messages: Monomer.
messages: The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters.

230089:VY86 RS11625
gene id: 230089:VY86_RS11625
uniprot id: A0A0F7LP73
names: Similarity
messages: Belongs to the short-chain fatty acyl-CoA assimilation regulator (ScfR) family.

230089:VY86 RS10425
gene id: 230089:VY86_RS10425
uniprot id: A0A0F7LPD9
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

230089:VY86 RS08585
gene id: 230089:VY86_RS08585
uniprot id: A0A0F7LNE3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal stress protein A family.
messages: Cytoplasm

230089:VY86 RS09050
gene id: 230089:VY86_RS09050
uniprot id: A0A0F7LLH0
names: Subcellular Location Annotation
messages: Membrane

230089:VY86 RS06575
gene id: 230089:VY86_RS06575
uniprot id: A0A0F7LLW9
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

230089:VY86 RS07570
gene id: 230089:VY86_RS07570
uniprot id: A0A0F7LN41
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

230089:VY86 RS14025
gene id: 230089:VY86_RS14025
uniprot id: A0A0F7LNW5
names: Similarity
messages: Belongs to the ClpA/ClpB family.

230089:VY86 RS15130
gene id: 230089:VY86_RS15130
uniprot id: A0A0F7LRI9
names: Similarity
messages: Belongs to the bacterial solute-binding protein ModA family.

230089:VY86 RS20275
gene id: 230089:VY86_RS20275
uniprot id: A0A0F7LU59
names: Function
names: Similarity
messages: Belongs to the MinE family.
messages: Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.

230089:VY86 RS08825
gene id: 230089:VY86_RS08825
uniprot id: A0A0F7LN50
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

230089:VY86 RS04195
gene id: 230089:VY86_RS04195
uniprot id: A0A0F7LV44
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.
messages: Binds 1 S-adenosyl-L-methionine per subunit.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

230089:VY86 RS20420
gene id: 230089:VY86_RS20420
uniprot id: A0A0F7LRQ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

230089:VY86 RS15425
gene id: 230089:VY86_RS15425
uniprot id: A0A0F7LS15
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.

230089:VY86 RS09875
gene id: 230089:VY86_RS09875
uniprot id: A0A0F7LLY8
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.

230089:VY86 RS05560
gene id: 230089:VY86_RS05560
uniprot id: A0A0F7LJP5
names: Similarity
messages: Belongs to the aspartokinase family.

230089:VY86 RS01545
gene id: 230089:VY86_RS01545
uniprot id: A0A0F7LK12
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

230089:VY86 RS08305
gene id: 230089:VY86_RS08305
uniprot id: A0A0F7LNC9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccA family.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

230089:VY86 RS13155
gene id: 230089:VY86_RS13155
uniprot id: A0A0F7LQ46
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

230089:VY86 RS22075
gene id: 230089:VY86_RS22075
uniprot id: A0A0F7LUN1
names: Function
names: Induction
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the SulA family.
messages: By DNA damage, as part of the SOS response.
messages: Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1:1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division.
messages: Interacts with FtsZ.
messages: Is rapidly cleaved and degraded by the Lon protease once DNA damage is repaired.

230089:VY86 RS11920
gene id: 230089:VY86_RS11920
uniprot id: A0A0F7LPV5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrC family.
messages: Cell membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

230089:VY86 RS18835
gene id: 230089:VY86_RS18835
uniprot id: A0A0F7LPF3
names: Similarity
messages: Belongs to the myoviridae tail sheath protein family.

230089:VY86 RS14775
gene id: 230089:VY86_RS14775
uniprot id: A0A0F7LP78
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

230089:VY86 RS17000
gene id: 230089:VY86_RS17000
uniprot id: A0A0F7LQD8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

230089:VY86 RS06885
gene id: 230089:VY86_RS06885
uniprot id: A0A0F7LMU2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

230089:VY86 RS01510
gene id: 230089:VY86_RS01510
uniprot id: A0A0F7LK08
names: Function
names: Subcellular Location Annotation
messages: Catalyzes the Claisen rearrangement of chorismate to prephenate and the decarboxylation/dehydration of prephenate to phenylpyruvate.
messages: Cytoplasm

230089:VY86 RS15510
gene id: 230089:VY86_RS15510
uniprot id: A0A0F7LRF2
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

230089:VY86 RS20135
gene id: 230089:VY86_RS20135
uniprot id: A0A0F7LTS8
names: Cofactor
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family.
messages: Binds 2 nickel ions per subunit.
messages: Carbamylation allows a single lysine to coordinate two nickel ions.
messages: Carboxylation allows a single lysine to coordinate two nickel ions.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

230089:VY86 RS05765
gene id: 230089:VY86_RS05765
uniprot id: A0A0F7LM71
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Bcr/CmlA family.
messages: Belongs to the major facilitator superfamily. TCR/Tet family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Resistance to tetracycline by an active tetracycline efflux. This is an energy-dependent process that decreases the accumulation of the antibiotic in whole cells. This protein functions as a metal-tetracycline/H(+) antiporter.

230089:VY86 RS13165
gene id: 230089:VY86_RS13165
uniprot id: A0A0F7LNN6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

230089:VY86 RS17930
gene id: 230089:VY86_RS17930
uniprot id: A0A0F7LQU6
names: Similarity
messages: In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.
messages: In the N-terminal section; belongs to the malic enzymes family.

230089:VY86 RS20815
gene id: 230089:VY86_RS20815
uniprot id: A0A0F7LU27
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

230089:VY86 RS03535
gene id: 230089:VY86_RS03535
uniprot id: A0A0F7LL62
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoS subfamily.
messages: Cytoplasm
messages: Interacts with the RNA polymerase core enzyme.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the master transcriptional regulator of the stationary phase and the general stress response.

230089:VY86 RS08105
gene id: 230089:VY86_RS08105
uniprot id: A0A0F7LNA1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0). The b'-subunit is a diverged and duplicated form of b found in plants and photosynthetic bacteria.
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

230089:VY86 RS06585
gene id: 230089:VY86_RS06585
uniprot id: A0A0F7LK71
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family. WecC subfamily.
messages: Catalyzes the four-electron oxidation of UDP-N-acetyl-D-mannosamine (UDP-ManNAc), reducing NAD(+) and releasing UDP-N-acetylmannosaminuronic acid (UDP-ManNAcA).
messages: Homodimer.

230089:VY86 RS11915
gene id: 230089:VY86_RS11915
uniprot id: A0A0F7LMX7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: Membrane
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

230089:VY86 RS22165
gene id: 230089:VY86_RS22165
uniprot id: A0A0F7LUY4
names: Similarity
messages: Belongs to the peptidase M1 family.

230089:VY86 RS18255
gene id: 230089:VY86_RS18255
uniprot id: A0A0F7LT24
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

230089:VY86 RS19855
gene id: 230089:VY86_RS19855
uniprot id: A0A0F7LTP0
names: Similarity
messages: Belongs to the PhzF family.

230089:VY86 RS02520
gene id: 230089:VY86_RS02520
uniprot id: A0A0F7LKK9
names: Function
messages: Member of the two-component regulatory system PhoR/PhoB involved in the phosphate regulon genes expression. PhoR may function as a membrane-associated protein kinase that phosphorylates PhoB in response to environmental signals.

230089:VY86 RS09330
gene id: 230089:VY86_RS09330
uniprot id: A0A0F7LNZ8
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

230089:VY86 RS07065
gene id: 230089:VY86_RS07065
uniprot id: A0A0F7LMW2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

230089:VY86 RS11395
gene id: 230089:VY86_RS11395
uniprot id: A0A0F7LPS7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Cell membrane
messages: Membrane
messages: Responsible for the transport of dicarboxylates such as succinate, fumarate, and malate across the membrane.

230089:VY86 RS06425
gene id: 230089:VY86_RS06425
uniprot id: A0A0F7LMI9
names: Similarity
messages: Belongs to the helicase family. RecQ subfamily.

230089:VY86 RS04635
gene id: 230089:VY86_RS04635
uniprot id: A0A0F7LHZ6
names: Function
names: Subunit
messages: Adenylyltransferase that mediates the addition of adenosine 5'-monophosphate (AMP) to specific residues of target proteins.
messages: Homodimer.

230089:VY86 RS14420
gene id: 230089:VY86_RS14420
uniprot id: A0A0F7LM78
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

230089:VY86 RS05595
gene id: 230089:VY86_RS05595
uniprot id: A0A0F7LLX6
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.

230089:VY86 RS05460
gene id: 230089:VY86_RS05460
uniprot id: A0A0F7LM05
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins.

230089:VY86 RS08345
gene id: 230089:VY86_RS08345
uniprot id: A0A0F7LMS6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
messages: Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).
messages: Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
messages: Cytoplasm

230089:VY86 RS20145
gene id: 230089:VY86_RS20145
uniprot id: A0A0F7LTV2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the urease gamma subunit family.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

230089:VY86 RS06125
gene id: 230089:VY86_RS06125
uniprot id: A0A0F7LLM5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in both the arginine and lysine biosynthetic pathways.

230089:VY86 RS15785
gene id: 230089:VY86_RS15785
uniprot id: A0A0F7LRX1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

230089:VY86 RS11100
gene id: 230089:VY86_RS11100
uniprot id: A0A0F7LPM5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fimbrial export usher family.
messages: Cell outer membrane
messages: Membrane

230089:VY86 RS02090
gene id: 230089:VY86_RS02090
uniprot id: A0A0F7LKF4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DEAD box helicase family. SrmB subfamily.
messages: Cytoplasm
messages: DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit at low temperature. Exhibits RNA-stimulated ATP hydrolysis and RNA unwinding activity.
messages: Interacts with the 50S ribosomal subunit.

230089:VY86 RS20520
gene id: 230089:VY86_RS20520
uniprot id: A0A0F7LTZ3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

230089:VY86 RS18615
gene id: 230089:VY86_RS18615
uniprot id: A0A0F7LVI7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 5 family.
messages: Periplasm

230089:VY86 RS16615
gene id: 230089:VY86_RS16615
uniprot id: A0A0F7LRY9
names: Subcellular Location Annotation
messages: Membrane

230089:VY86 RS14410
gene id: 230089:VY86_RS14410
uniprot id: A0A0F7LRD5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Cell inner membrane
messages: Membrane

230089:VY86 RS15585
gene id: 230089:VY86_RS15585
uniprot id: A0A0F7LS26
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. RlmC subfamily.
messages: Catalyzes the formation of 5-methyl-uridine at position 747 (m5U747) in 23S rRNA.

230089:VY86 RS18135
gene id: 230089:VY86_RS18135
uniprot id: A0A0F7LT74
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

230089:VY86 RS06870
gene id: 230089:VY86_RS06870
uniprot id: A0A0F7LJ14
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

230089:VY86 RS05415
gene id: 230089:VY86_RS05415
uniprot id: A0A0F7LLU1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 1 subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

230089:VY86 RS19910
gene id: 230089:VY86_RS19910
uniprot id: A0A0F7LTP6
names: Similarity
messages: Belongs to the peptidase S58 family.

230089:VY86 RS06565
gene id: 230089:VY86_RS06565
uniprot id: A0A0F7LMG3
names: Function
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.
messages: Catalyzes the synthesis of dTDP-4-amino-4,6-dideoxy-D-galactose (dTDP-Fuc4N) from dTDP-4-keto-6-deoxy-D-glucose (dTDP-D-Glc4O) and L-glutamate.

230089:VY86 RS01635
gene id: 230089:VY86_RS01635
uniprot id: A0A0F7LGF0
names: Caution
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family. AroL subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: The LID domain closes over the active site upon ATP binding.

230089:VY86 RS18725
gene id: 230089:VY86_RS18725
uniprot id: A0A0F7LR73
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Homodimer.
messages: Multifunctional regulator of fatty acid metabolism.

230089:VY86 RS00525
gene id: 230089:VY86_RS00525
uniprot id: A0A0F7LG34
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the arginase family.
messages: Binds 2 manganese ions per subunit.
messages: Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide.

230089:VY86 RS12935
gene id: 230089:VY86_RS12935
uniprot id: A0A0F7LQ14
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily. RsmD family.
messages: Specifically methylates the guanine in position 966 of 16S rRNA in the assembled 30S particle.

230089:VY86 RS12900
gene id: 230089:VY86_RS12900
uniprot id: A0A0F7LQK4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily.
messages: Cell inner membrane
messages: Involved in the import of queuosine (Q) precursors, required for Q precursor salvage.

230089:VY86 RS00440
gene id: 230089:VY86_RS00440
uniprot id: A0A0F7LUS0
names: Similarity
messages: Belongs to the UPF0065 (bug) family.

230089:VY86 RS06410
gene id: 230089:VY86_RS06410
uniprot id: A0A0F7LIT1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone-like protein H-NS family.
messages: nucleoid

230089:VY86 RS07310
gene id: 230089:VY86_RS07310
uniprot id: A0A0F7LJ81
names: Similarity
messages: Belongs to the ner transcriptional regulatory family.

230089:VY86 RS18220
gene id: 230089:VY86_RS18220
uniprot id: A0A0F7LT09
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 83 family.
messages: Catalyzes the transfer of the L-Ara4N moiety of the glycolipid undecaprenyl phosphate-alpha-L-Ara4N to lipid A. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

230089:VY86 RS07995
gene id: 230089:VY86_RS07995
uniprot id: A0A0F7LN83
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

230089:VY86 RS02170
gene id: 230089:VY86_RS02170
uniprot id: A0A0F7LPN2
names: Similarity
messages: Belongs to the transposase 11 family.

230089:VY86 RS03560
gene id: 230089:VY86_RS03560
uniprot id: A0A0F7LL65
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IspF family.
messages: Binds 1 divalent metal cation per subunit.
messages: Homotrimer.
messages: Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).

230089:VY86 RS15845
gene id: 230089:VY86_RS15845
uniprot id: A0A0F7LRX8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
messages: Belongs to the KdsB family.
messages: Cytoplasm

230089:VY86 RS19360
gene id: 230089:VY86_RS19360
uniprot id: A0A0F7LRE0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell inner membrane
messages: Membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

230089:VY86 RS13440
gene id: 230089:VY86_RS13440
uniprot id: A0A0F7LQT9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Membrane

230089:VY86 RS01610
gene id: 230089:VY86_RS01610
uniprot id: A0A0F7LHV5
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm
messages: Homotetramer.

230089:VY86 RS18465
gene id: 230089:VY86_RS18465
uniprot id: A0A0F7LP86
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

230089:VY86 RS02710
gene id: 230089:VY86_RS02710
uniprot id: A0A0F7LIA5
names: Subcellular Location Annotation
messages: Membrane

230089:VY86 RS16295
gene id: 230089:VY86_RS16295
uniprot id: A0A0F7LS24
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TPP enzyme family. MenD subfamily.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC).
messages: Homodimer.

230089:VY86 RS06155
gene id: 230089:VY86_RS06155
uniprot id: A0A0F7LMC8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbA subfamily.
messages: Periplasm

230089:VY86 RS04475
gene id: 230089:VY86_RS04475
uniprot id: A0A0F7LLE1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Syd family.
messages: Cell inner membrane
messages: Interacts with the SecY protein in vivo. May bind preferentially to an uncomplexed state of SecY, thus functioning either as a chelating agent for excess SecY in the cell or as a regulatory factor that negatively controls the translocase function.

230089:VY86 RS07160
gene id: 230089:VY86_RS07160
uniprot id: A0A0F7LMV1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsN family.
messages: Cell inner membrane
messages: Essential cell division protein that activates septal peptidoglycan synthesis and constriction of the cell. Acts on both sides of the membrane, via interaction with FtsA in the cytoplasm and interaction with the FtsQBL complex in the periplasm. These interactions may induce a conformational switch in both FtsA and FtsQBL, leading to septal peptidoglycan synthesis by FtsI and associated synthases.
messages: Interacts with FtsA via its N-terminal cytoplasmic domain.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

230089:VY86 RS10605
gene id: 230089:VY86_RS10605
uniprot id: A0A0F7LKQ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

230089:VY86 RS20405
gene id: 230089:VY86_RS20405
uniprot id: A0A0F7LU81
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvB family.
messages: Cytoplasm
messages: Has 3 domains, the large (RuvB-L) and small ATPase (RuvB-S) domains and the C-terminal head (RuvB-H) domain. The head domain binds DNA, while the ATPase domains jointly bind ATP, ADP or are empty depending on the state of the subunit in the translocation cycle. During a single DNA translocation step the structure of each domain remains the same, but their relative positions change.
messages: Homohexamer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time. Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange. Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration. The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration. Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.

230089:VY86 RS12990
gene id: 230089:VY86_RS12990
uniprot id: A0A0F7LT04
names: Similarity
messages: Belongs to the ABC transporter superfamily.

230089:VY86 RS18605
gene id: 230089:VY86_RS18605
uniprot id: A0A0F7LTG7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

230089:VY86 RS05965
gene id: 230089:VY86_RS05965
uniprot id: A0A0F7LLL0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

230089:VY86 RS18980
gene id: 230089:VY86_RS18980
uniprot id: A0A0F7LTM3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

230089:VY86 RS16755
gene id: 230089:VY86_RS16755
uniprot id: A0A0F7LQB7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CbiN family.
messages: Cell membrane
messages: Forms an energy-coupling factor (ECF) transporter complex composed of an ATP-binding protein (A component, CbiO), a transmembrane protein (T component, CbiQ) and 2 possible substrate-capture proteins (S components, CbiM and CbiN) of unknown stoichimetry.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import.

230089:VY86 RS00410
gene id: 230089:VY86_RS00410
uniprot id: A0A0F7LJ02
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. PdxB subfamily.
messages: Catalyzes the oxidation of erythronate-4-phosphate to 3-hydroxy-2-oxo-4-phosphonooxybutanoate.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

230089:VY86 RS00530
gene id: 230089:VY86_RS00530
uniprot id: A0A0F7LHE0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metallo-dependent hydrolases superfamily. HutI family.
messages: Binds 1 zinc or iron ion per subunit.
messages: Catalyzes the hydrolytic cleavage of the carbon-nitrogen bond in imidazolone-5-propanoate to yield N-formimidoyl-L-glutamate. It is the third step in the universal histidine degradation pathway.
messages: Cytoplasm

230089:VY86 RS15430
gene id: 230089:VY86_RS15430
uniprot id: A0A0F7LRD9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uridine kinase family.
messages: Cytoplasm

230089:VY86 RS14500
gene id: 230089:VY86_RS14500
uniprot id: A0A0F7LRE7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvT family.
messages: The glycine cleavage system catalyzes the degradation of glycine.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

230089:VY86 RS14725
gene id: 230089:VY86_RS14725
uniprot id: A0A0F7LRA7
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transglycosylase Slt family.
messages: Cell outer membrane
messages: In the C-terminal section; belongs to the transglycosylase Slt family.
messages: In the N-terminal section; belongs to the bacterial solute-binding protein 3 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella.
messages: The N-terminal domain does not have lytic activity and probably modulates enzymatic activity. The C-terminal domain is the catalytic active domain.

230089:VY86 RS19015
gene id: 230089:VY86_RS19015
uniprot id: A0A0F7LTA5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TonB family.
messages: Cell inner membrane
messages: Homodimer. Forms a complex with the accessory proteins ExbB and ExbD.
messages: Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins.

230089:VY86 RS04140
gene id: 230089:VY86_RS04140
uniprot id: A0A0F7LHQ8
names: Subcellular Location Annotation
messages: Membrane

230089:VY86 RS15485
gene id: 230089:VY86_RS15485
uniprot id: A0A0F7LRE8
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the C-terminal section; belongs to the PRA-PH family.
messages: In the N-terminal section; belongs to the PRA-CH family.

230089:VY86 RS08085
gene id: 230089:VY86_RS08085
uniprot id: A0A0F7LN91
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family. T3SS ATPase subfamily.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

230089:VY86 RS13895
gene id: 230089:VY86_RS13895
uniprot id: A0A0F7LPN2
names: Similarity
messages: Belongs to the transposase 11 family.

230089:VY86 RS12740
gene id: 230089:VY86_RS12740
uniprot id: A0A0F7LLL2
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

230089:VY86 RS18100
gene id: 230089:VY86_RS18100
uniprot id: A0A0F7LSU0
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Membrane

230089:VY86 RS03585
gene id: 230089:VY86_RS03585
uniprot id: A0A0F7LKY9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PAPS reductase family. CysD subfamily.
messages: Heterodimer composed of CysD, the smaller subunit, and CysN.
messages: With CysN forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway. APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD.

230089:VY86 RS17190
gene id: 230089:VY86_RS17190
uniprot id: A0A0F7LSC4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LpoB family.
messages: Cell outer membrane
messages: Interacts with PBP1b.
messages: Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b).

230089:VY86 RS02730
gene id: 230089:VY86_RS02730
uniprot id: A0A0F7LK14
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Membrane
messages: The cytochrome bo(3) ubiquinol oxidase complex is a heterooctamer of two A chains, two B chains, two C chains and two D chains.

230089:VY86 RS15830
gene id: 230089:VY86_RS15830
uniprot id: A0A0F7LRJ3
names: Function
names: Similarity
messages: Belongs to the LpxK family.
messages: Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).

230089:VY86 RS10355
gene id: 230089:VY86_RS10355
uniprot id: A0A0F7LPA1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

230089:VY86 RS17255
gene id: 230089:VY86_RS17255
uniprot id: A0A0F7LVI3
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.
messages: In the N-terminal section; belongs to the transposase 2 family.

230089:VY86 RS05935
gene id: 230089:VY86_RS05935
uniprot id: A0A0F7LM94
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

230089:VY86 RS05305
gene id: 230089:VY86_RS05305
uniprot id: A0A0F7LLS0
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

230089:VY86 RS16240
gene id: 230089:VY86_RS16240
uniprot id: A0A0F7LS21
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 1 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 13 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.

230089:VY86 RS16975
gene id: 230089:VY86_RS16975
uniprot id: A0A0F7LQD6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid/polyamine transporter 2 family. Mtr/TnaB/TyrP permease subfamily.
messages: Cell inner membrane
messages: Involved in transporting aromatic amino acids across the cytoplasmic membrane.
messages: Membrane

230089:VY86 RS17005
gene id: 230089:VY86_RS17005
uniprot id: A0A0F7LSA6
names: Subcellular Location Annotation
messages: Membrane

230089:VY86 RS12940
gene id: 230089:VY86_RS12940
uniprot id: A0A0F7LLQ8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. SRP is a ribonucleoprotein composed of Ffh and a 4.5S RNA molecule.

230089:VY86 RS19340
gene id: 230089:VY86_RS19340
uniprot id: A0A0F7LTG1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RnfG family.
messages: Cell inner membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

230089:VY86 RS19440
gene id: 230089:VY86_RS19440
uniprot id: A0A0F7LPP0
names: Cofactor
names: Similarity
messages: Belongs to the mannose-6-phosphate isomerase type 1 family.
messages: Binds 1 zinc ion per subunit.

230089:VY86 RS04810
gene id: 230089:VY86_RS04810
uniprot id: A0A0F7LL60
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane
messages: The complex is composed of two ATP-binding proteins (ThiQ), two transmembrane proteins (ThiP) and a solute-binding protein (ThiB).

230089:VY86 RS16970
gene id: 230089:VY86_RS16970
uniprot id: A0A0F7LN94
names: Similarity
messages: Belongs to the elongation factor P family.

230089:VY86 RS12815
gene id: 230089:VY86_RS12815
uniprot id: A0A0F7LQJ8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

230089:VY86 RS05275
gene id: 230089:VY86_RS05275
uniprot id: A0A0F7LLR8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phosphopentomutase family.
messages: Binds 1 or 2 manganese ions.
messages: Cytoplasm
messages: Phosphotransfer between the C1 and C5 carbon atoms of pentose.

230089:VY86 RS21130
gene id: 230089:VY86_RS21130
uniprot id: A0A0F7LU76
names: Similarity
names: Subunit
messages: Belongs to the serine/threonine dehydratase family. DsdA subfamily.
messages: Monomer.

230089:VY86 RS17545
gene id: 230089:VY86_RS17545
uniprot id: A0A0F7LNF6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

230089:VY86 RS12620
gene id: 230089:VY86_RS12620
uniprot id: A0A0F7LQH5
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

230089:VY86 RS11180
gene id: 230089:VY86_RS11180
uniprot id: A0A0F7LPN5
names: Subcellular Location Annotation
messages: Secreted

230089:VY86 RS01650
gene id: 230089:VY86_RS01650
uniprot id: A0A0F7LK30
names: Function
names: Similarity
messages: Belongs to the FrsA family.
messages: Catalyzes the hydrolysis of esters.

230089:VY86 RS21845
gene id: 230089:VY86_RS21845
uniprot id: A0A0F7LQS1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MgtC/SapB family.
messages: Cell inner membrane
messages: Membrane

230089:VY86 RS20475
gene id: 230089:VY86_RS20475
uniprot id: A0A0F7LRQ6
names: Similarity
messages: Belongs to the VgrG protein family.

230089:VY86 RS03300
gene id: 230089:VY86_RS03300
uniprot id: A0A0F7LKS9
names: Similarity
messages: Belongs to the transposase 11 family.

230089:VY86 RS11945
gene id: 230089:VY86_RS11945
uniprot id: A0A0F7LPV7
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SIS family. GmhA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate.
messages: Cytoplasm
messages: Homotetramer.
messages: The reaction produces a racemic mixture of D-glycero-alpha-D-manno-heptose 7-phosphate and D-glycero-beta-D-manno-heptose 7-phosphate.

230089:VY86 RS06825
gene id: 230089:VY86_RS06825
uniprot id: A0A0F7LMH9
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

230089:VY86 RS00135
gene id: 230089:VY86_RS00135
uniprot id: A0A0F7LFY9
names: Subcellular Location Annotation
messages: Membrane

230089:VY86 RS03270
gene id: 230089:VY86_RS03270
uniprot id: A0A0F7LV25
names: Similarity
messages: Belongs to the ner transcriptional regulatory family.

230089:VY86 RS07070
gene id: 230089:VY86_RS07070
uniprot id: A0A0F7LM69
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm
messages: In the N-terminal section; belongs to the lyase 1 family. Argininosuccinate lyase subfamily.

230089:VY86 RS05775
gene id: 230089:VY86_RS05775
uniprot id: A0A0F7LIF5
names: Function
names: Similarity
messages: Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis.
messages: Belongs to the glycogen phosphorylase family.
messages: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.

230089:VY86 RS08890
gene id: 230089:VY86_RS08890
uniprot id: A0A0F7LLC2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NfuA family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is presumably bound at the interface of two monomers.
messages: Homodimer.
messages: Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins.

230089:VY86 RS14940
gene id: 230089:VY86_RS14940
uniprot id: A0A0F7LRQ8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

230089:VY86 RS20230
gene id: 230089:VY86_RS20230
uniprot id: A0A0F7LTV8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Also exhibits azoreductase activity. Catalyzes the reductive cleavage of the azo bond in aromatic azo compounds to the corresponding amines.
messages: Belongs to the azoreductase type 1 family.
messages: Binds 1 FMN per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Quinone reductase that provides resistance to thiol-specific stress caused by electrophilic quinones.

230089:VY86 RS02585
gene id: 230089:VY86_RS02585
uniprot id: A0A0F7LGX2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

230089:VY86 RS06690
gene id: 230089:VY86_RS06690
uniprot id: A0A0F7LK89
names: Subcellular Location Annotation
messages: Membrane

230089:VY86 RS14915
gene id: 230089:VY86_RS14915
uniprot id: A0A0F7LRQ4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane
messages: Membrane

230089:VY86 RS02855
gene id: 230089:VY86_RS02855
uniprot id: A0A0F7LK22
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

230089:VY86 RS07180
gene id: 230089:VY86_RS07180
uniprot id: A0A0F7LKK4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RraA family.
messages: Cytoplasm
messages: Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome.
messages: Homotrimer. Binds to both RNA-binding sites in the C-terminal region of Rne and to RhlB.

230089:VY86 RS08170
gene id: 230089:VY86_RS08170
uniprot id: A0A0F7LJP8
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

230089:VY86 RS20650
gene id: 230089:VY86_RS20650
uniprot id: A0A0F7LQ84
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.
messages: Homodimer.

230089:VY86 RS04200
gene id: 230089:VY86_RS04200
uniprot id: A0A0F7LJ41
names: Subcellular Location Annotation
messages: Membrane

230089:VY86 RS08100
gene id: 230089:VY86_RS08100
uniprot id: A0A0F7LL34
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase delta chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

230089:VY86 RS15595
gene id: 230089:VY86_RS15595
uniprot id: A0A0F7LMP4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

230089:VY86 RS17960
gene id: 230089:VY86_RS17960
uniprot id: A0A0F7LVJ1
names: Activity Regulation
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

230089:VY86 RS21460
gene id: 230089:VY86_RS21460
uniprot id: A0A0F7LSA7
names: Function
names: Similarity
messages: Belongs to the FlgM family.
messages: Responsible for the coupling of flagellin expression to flagellar assembly by preventing expression of the flagellin genes when a component of the middle class of proteins is defective. It negatively regulates flagellar genes by inhibiting the activity of FliA by directly binding to FliA.

230089:VY86 RS18740
gene id: 230089:VY86_RS18740
uniprot id: A0A0F7LT84
names: Similarity
messages: Belongs to the MipA/OmpV family.

230089:VY86 RS09115
gene id: 230089:VY86_RS09115
uniprot id: A0A0F7LLH9
names: Subcellular Location Annotation
messages: Membrane

230089:VY86 RS06800
gene id: 230089:VY86_RS06800
uniprot id: A0A0F7LMH8
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

230089:VY86 RS13445
gene id: 230089:VY86_RS13445
uniprot id: A0A0F7LQ86
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TerC family.
messages: Membrane

230089:VY86 RS04830
gene id: 230089:VY86_RS04830
uniprot id: A0A0F7LLR5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

230089:VY86 RS20025
gene id: 230089:VY86_RS20025
uniprot id: A0A0F7LRK8
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

230089:VY86 RS04385
gene id: 230089:VY86_RS04385
uniprot id: A0A0F7LJ61
names: Similarity
messages: Belongs to the skp family.

230089:VY86 RS14455
gene id: 230089:VY86_RS14455
uniprot id: A0A0F7LR41
names: Similarity
messages: Belongs to the citrate synthase family.

230089:VY86 RS07865
gene id: 230089:VY86_RS07865
uniprot id: A0A0F7LMK0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the nucleoid occlusion factor SlmA family.
messages: Homodimer. Interacts with FtsZ.
messages: Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid. Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers. SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions.
messages: nucleoid

230089:VY86 RS19810
gene id: 230089:VY86_RS19810
uniprot id: A0A0F7LRH4
names: Similarity
messages: Belongs to the site-specific recombinase resolvase family.

230089:VY86 RS14885
gene id: 230089:VY86_RS14885
uniprot id: A0A0F7LRF5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MraZ family.
messages: Forms oligomers.
messages: Negatively regulates its own expression and that of the subsequent genes in the proximal part of the division and cell wall (dcw) gene cluster. Acts by binding directly to DNA. May also regulate the expression of genes outside the dcw cluster.
messages: nucleoid

230089:VY86 RS10365
gene id: 230089:VY86_RS10365
uniprot id: A0A0F7LNR3
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

230089:VY86 RS04150
gene id: 230089:VY86_RS04150
uniprot id: A0A0F7LLA2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

230089:VY86 RS06140
gene id: 230089:VY86_RS06140
uniprot id: A0A0F7LK06
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

230089:VY86 RS01480
gene id: 230089:VY86_RS01480
uniprot id: A0A0F7LK88
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.

230089:VY86 RS18430
gene id: 230089:VY86_RS18430
uniprot id: A0A0F7LTD2
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

230089:VY86 RS02405
gene id: 230089:VY86_RS02405
uniprot id: A0A0F7LJU3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SctL stator family.
messages: Cytoplasm

230089:VY86 RS07840
gene id: 230089:VY86_RS07840
uniprot id: A0A0F7LJJ2
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

230089:VY86 RS12625
gene id: 230089:VY86_RS12625
uniprot id: A0A0F7LPX1
names: Similarity
messages: Belongs to the RNase T2 family.

230089:VY86 RS02055
gene id: 230089:VY86_RS02055
uniprot id: A0A0F7LV31
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

230089:VY86 RS13300
gene id: 230089:VY86_RS13300
uniprot id: A0A0F7LNP8
names: Similarity
messages: Belongs to the BolA/IbaG family.

230089:VY86 RS15620
gene id: 230089:VY86_RS15620
uniprot id: A0A0F7LMP6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

230089:VY86 RS08180
gene id: 230089:VY86_RS08180
uniprot id: A0A0F7LNA7
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.
messages: Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.
messages: Belongs to the carbohydrate kinase pfkB family.
messages: Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
messages: Cytoplasm
messages: Homodimer.
messages: Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate.

230089:VY86 RS18580
gene id: 230089:VY86_RS18580
uniprot id: A0A0F7LTG5
names: Similarity
messages: Belongs to the GST superfamily.

230089:VY86 RS19130
gene id: 230089:VY86_RS19130
uniprot id: A0A0F7LTD7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

230089:VY86 RS15535
gene id: 230089:VY86_RS15535
uniprot id: A0A0F7LRF4
names: Function
names: Similarity
messages: Belongs to the peptidase S11 family.
messages: Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors.

230089:VY86 RS18200
gene id: 230089:VY86_RS18200
uniprot id: A0A0F7LNX0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DegT/DnrJ/EryC1 family. ArnB subfamily.
messages: Catalyzes the conversion of UDP-4-keto-arabinose (UDP-Ara4O) to UDP-4-amino-4-deoxy-L-arabinose (UDP-L-Ara4N). The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides.
messages: Homodimer.

230089:VY86 RS00675
gene id: 230089:VY86_RS00675
uniprot id: A0A0F7LHF9
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Membrane
messages: Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (CysA), two transmembrane proteins (CysT and CysW) and a solute-binding protein (CysP).

230089:VY86 RS19890
gene id: 230089:VY86_RS19890
uniprot id: A0A0F7LPW2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

230089:VY86 RS10945
gene id: 230089:VY86_RS10945
uniprot id: A0A0F7LMJ7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell membrane
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

230089:VY86 RS07125
gene id: 230089:VY86_RS07125
uniprot id: A0A0F7LJ40
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

230089:VY86 RS00860
gene id: 230089:VY86_RS00860
uniprot id: A0A0F7LHJ4
names: Subcellular Location Annotation
messages: Membrane

230089:VY86 RS07875
gene id: 230089:VY86_RS07875
uniprot id: A0A0F7LL04
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase PH family.
messages: Homohexameric ring arranged as a trimer of dimers.
messages: Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.

230089:VY86 RS02740
gene id: 230089:VY86_RS02740
uniprot id: A0A0F7LIB0
names: Similarity
messages: Belongs to the nucleoside-specific channel-forming outer membrane porin (Tsx) (TC 1.B.10) family.

230089:VY86 RS08960
gene id: 230089:VY86_RS08960
uniprot id: A0A0F7LJZ6
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family. GreB subfamily.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length.

230089:VY86 RS02700
gene id: 230089:VY86_RS02700
uniprot id: A0A0F7LJY7
names: Function
names: Similarity
messages: Belongs to the ketopantoate reductase family.
messages: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.

230089:VY86 RS20635
gene id: 230089:VY86_RS20635
uniprot id: A0A0F7LU44
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

230089:VY86 RS07630
gene id: 230089:VY86_RS07630
uniprot id: A0A0F7LN43
names: Subcellular Location Annotation
messages: Membrane

230089:VY86 RS04115
gene id: 230089:VY86_RS04115
uniprot id: A0A0F7LJ28
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid/polyamine transporter 2 family. Mtr/TnaB/TyrP permease subfamily.
messages: Cell inner membrane
messages: Involved in transporting aromatic amino acids across the cytoplasmic membrane.
messages: Membrane

230089:VY86 RS07955
gene id: 230089:VY86_RS07955
uniprot id: A0A0F7LV05
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FdhD family.
messages: Cytoplasm
messages: Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH.

230089:VY86 RS10640
gene id: 230089:VY86_RS10640
uniprot id: A0A0F7LPF0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptF/LptG family.
messages: Component of the lipopolysaccharide transport and assembly complex. The LptBFG transporter is composed of two ATP-binding proteins (LptB) and two transmembrane proteins (LptF and LptG).
messages: Membrane
messages: Part of the ABC transporter complex LptBFG involved in the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane.

230089:VY86 RS17025
gene id: 230089:VY86_RS17025
uniprot id: A0A0F7LQD9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

230089:VY86 RS10300
gene id: 230089:VY86_RS10300
uniprot id: A0A0F7LNR0
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

230089:VY86 RS14200
gene id: 230089:VY86_RS14200
uniprot id: A0A0F7LRA3
names: Function
names: Similarity
messages: Belongs to the flavodoxin family.
messages: Low-potential electron donor to a number of redox enzymes.

230089:VY86 RS13245
gene id: 230089:VY86_RS13245
uniprot id: A0A0F7LNP2
names: Function
names: Similarity
messages: Belongs to the ABC transporter superfamily. Outer membrane lipopolysaccharide export (TC 1.B.42) family.
messages: Part of the ABC transporter complex LptBFG involved in the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane. Probably responsible for energy coupling to the transport system.

230089:VY86 RS12535
gene id: 230089:VY86_RS12535
uniprot id: A0A0F7LQG5
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

230089:VY86 RS09020
gene id: 230089:VY86_RS09020
uniprot id: A0A0F7LLE8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Part of the phosphate (Pho) regulon, which plays a key role in phosphate homeostasis. PhoU is essential for the repression of the Pho regulon at high phosphate conditions.

230089:VY86 RS15520
gene id: 230089:VY86_RS15520
uniprot id: A0A0F7LPR5
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATP phosphoribosyltransferase family. Long subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Equilibrium between an active dimeric form, an inactive hexameric form and higher aggregates. Interconversion between the various forms is largely reversible and is influenced by the natural substrates and inhibitors of the enzyme.
messages: Feedback inhibited by histidine.

230089:VY86 RS00815
gene id: 230089:VY86_RS00815
uniprot id: A0A0F7LJR0
names: Function
names: Similarity
messages: Belongs to the heat shock protein 70 family.
messages: Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB. Involved in the maturation of IscU.

230089:VY86 RS13685
gene id: 230089:VY86_RS13685
uniprot id: A0A0F7LNT7
names: Function
names: Similarity
names: Subunit
messages: Acts on ADP-mannose and ADP-glucose as well as ADP-ribose. Prevents glycogen biosynthesis. The reaction catalyzed by this enzyme is a limiting step of the gluconeogenic process.
messages: Belongs to the Nudix hydrolase family. NudF subfamily.
messages: Homodimer.

230089:VY86 RS08425
gene id: 230089:VY86_RS08425
uniprot id: A0A0F7LND3
names: Similarity
messages: Belongs to the pirin family.

230089:VY86 RS21440
gene id: 230089:VY86_RS21440
uniprot id: A0A0F7LUL0
names: Function
names: Similarity
messages: Belongs to the FlgD family.
messages: Required for flagellar hook formation. May act as a scaffolding protein.

230089:VY86 RS19870
gene id: 230089:VY86_RS19870
uniprot id: A0A0F7LRL2
names: Similarity
messages: Belongs to the peptidase S58 family.

230089:VY86 RS16990
gene id: 230089:VY86_RS16990
uniprot id: A0A0F7LS61
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the AP endonuclease 2 family.
messages: Binds 3 Zn(2+) ions.
messages: Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate.

230089:VY86 RS02910
gene id: 230089:VY86_RS02910
uniprot id: A0A0F7LH33
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

230089:VY86 RS16985
gene id: 230089:VY86_RS16985
uniprot id: A0A0F7LSL4
names: Function
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.
messages: Catalyzes the ATP-dependent phosphorylation of fructose-l-phosphate to fructose-l,6-bisphosphate.

230089:VY86 RS10750
gene id: 230089:VY86_RS10750
uniprot id: A0A0F7LPH2
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

230089:VY86 RS06730
gene id: 230089:VY86_RS06730
uniprot id: A0A0F7LM09
names: Function
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.
messages: Negatively regulates the transcription of the flagellar master operon flhDC by binding to the upstream region of the operon.

230089:VY86 RS18915
gene id: 230089:VY86_RS18915
uniprot id: A0A0F7LPF8
names: Function
names: Similarity
messages: Belongs to the PurU family.
messages: Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).

230089:VY86 RS15420
gene id: 230089:VY86_RS15420
uniprot id: A0A0F7LRS5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.

230089:VY86 RS15885
gene id: 230089:VY86_RS15885
uniprot id: A0A0F7LV82
names: Function
names: Similarity
messages: Belongs to the transposase 11 family.
messages: Involved in the transposition of the insertion sequence IS5.

230089:VY86 RS05450
gene id: 230089:VY86_RS05450
uniprot id: A0A0F7LJM8
names: Function
names: Similarity
messages: Belongs to the Dus family. DusA subfamily.
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U20 and U20a in tRNAs.

230089:VY86 RS02025
gene id: 230089:VY86_RS02025
uniprot id: A0A0F7LKA2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Cytoplasm
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

230089:VY86 RS23980
gene id: 230089:VY86_RS23980
uniprot id: A0A0F7LKX0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioester dehydratase family. FabZ subfamily.
messages: Cytoplasm
messages: Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.

230089:VY86 RS07975
gene id: 230089:VY86_RS07975
uniprot id: A0A0F7LML6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Cell membrane
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

230089:VY86 RS15500
gene id: 230089:VY86_RS15500
uniprot id: A0A0F7LRT3
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

230089:VY86 RS21175
gene id: 230089:VY86_RS21175
uniprot id: A0A0F7LUF8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sigma-70 factor family. FliA subfamily.
messages: Cytoplasm
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor controls the expression of flagella-related genes.

230089:VY86 RS02030
gene id: 230089:VY86_RS02030
uniprot id: A0A0F7LKE5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PNP synthase family.
messages: Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.
messages: Cytoplasm
messages: Homooctamer; tetramer of dimers.

230089:VY86 RS14325
gene id: 230089:VY86_RS14325
uniprot id: A0A0F7LM68
names: Function
names: Similarity
messages: Belongs to the class-I DAHP synthase family.
messages: Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP).

230089:VY86 RS18645
gene id: 230089:VY86_RS18645
uniprot id: A0A0F7LPC9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0283 family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

230089:VY86 RS22190
gene id: 230089:VY86_RS22190
uniprot id: A0A0F7LUY9
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.

230089:VY86 RS15495
gene id: 230089:VY86_RS15495
uniprot id: A0A0F7LPQ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

230089:VY86 RS19925
gene id: 230089:VY86_RS19925
uniprot id: A0A0F7LTQ7
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

230089:VY86 RS18060
gene id: 230089:VY86_RS18060
uniprot id: A0A0F7LSX1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferritin family. Prokaryotic subfamily.
messages: Cytoplasm
messages: Iron-storage protein.

230089:VY86 RS18550
gene id: 230089:VY86_RS18550
uniprot id: A0A0F7LTG3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SlyA family.
messages: Homodimer.
messages: Transcription regulator that can specifically activate or repress expression of target genes.

230089:VY86 RS19380
gene id: 230089:VY86_RS19380
uniprot id: A0A0F7LKS9
names: Similarity
messages: Belongs to the transposase 11 family.

230089:VY86 RS06510
gene id: 230089:VY86_RS06510
uniprot id: A0A0F7LIU4
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Involved in a late step of protoheme IX synthesis.
messages: Membrane

230089:VY86 RS21390
gene id: 230089:VY86_RS21390
uniprot id: A0A0F7LUK4
names: Similarity
messages: Belongs to the VgrG protein family.

230089:VY86 RS21835
gene id: 230089:VY86_RS21835
uniprot id: A0A0F7LUU6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FlhC family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Functions in complex with FlhD as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region. Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes. Also regulates genes whose products function in a variety of physiological pathways.
messages: Heterohexamer composed of two FlhC and four FlhD subunits. Each FlhC binds a FlhD dimer, forming a heterotrimer, and a hexamer assembles by dimerization of two heterotrimers.

230089:VY86 RS18750
gene id: 230089:VY86_RS18750
uniprot id: A0A0F7LR77
names: Cofactor
names: Similarity
messages: Belongs to the MsrB Met sulfoxide reductase family.
messages: Binds 1 zinc ion per subunit. The zinc ion is important for the structural integrity of the protein.

230089:VY86 RS18310
gene id: 230089:VY86_RS18310
uniprot id: A0A0F7LTA2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

230089:VY86 RS00515
gene id: 230089:VY86_RS00515
uniprot id: A0A0F7LJS8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the urocanase family.
messages: Binds 1 NAD(+) per subunit.
messages: Catalyzes the conversion of urocanate to 4-imidazolone-5-propionate.
messages: Cytoplasm

230089:VY86 RS09145
gene id: 230089:VY86_RS09145
uniprot id: A0A0F7LLI2
names: Similarity
messages: Belongs to the RelB/DinJ antitoxin family.

230089:VY86 RS22025
gene id: 230089:VY86_RS22025
uniprot id: A0A0F7LUU7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endonuclease Cas1 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas2 homodimer.

230089:VY86 RS00360
gene id: 230089:VY86_RS00360
uniprot id: A0A0F7LHB0
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. SDR39U1 subfamily.

230089:VY86 RS10985
gene id: 230089:VY86_RS10985
uniprot id: A0A0F7LP05
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M24B family. Bacterial-type prolidase subfamily.
messages: Binds 2 manganese ions per subunit.
messages: Splits dipeptides with a prolyl residue in the C-terminal position.

230089:VY86 RS20915
gene id: 230089:VY86_RS20915
uniprot id: A0A0F7LQB8
names: Function
messages: Colicins are polypeptide toxins produced by and active against E.coli and closely related bacteria.

230089:VY86 RS04600
gene id: 230089:VY86_RS04600
uniprot id: A0A0F7LLG6
names: Function
messages: Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and/or cell division.

230089:VY86 RS20440
gene id: 230089:VY86_RS20440
uniprot id: A0A0F7LQ59
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. Cx-SAM synthase family.
messages: Catalyzes the conversion of S-adenosyl-L-methionine (SAM) to carboxy-S-adenosyl-L-methionine (Cx-SAM).
messages: Homodimer.

230089:VY86 RS14615
gene id: 230089:VY86_RS14615
uniprot id: A0A0F7LQU4
names: Similarity
messages: Belongs to the P(II) protein family.

230089:VY86 RS20195
gene id: 230089:VY86_RS20195
uniprot id: A0A0F7LU46
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Basic amino acid/polyamine antiporter (APA) (TC 2.A.3.2) family.
messages: Membrane

230089:VY86 RS03040
gene id: 230089:VY86_RS03040
uniprot id: A0A0F7LKV2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

230089:VY86 RS20655
gene id: 230089:VY86_RS20655
uniprot id: A0A0F7LRT0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

230089:VY86 RS06085
gene id: 230089:VY86_RS06085
uniprot id: A0A0F7LM57
names: Function
names: Induction
names: Miscellaneous
names: Similarity
names: Subunit
messages: A lyase-type mechanism (elimination/hydration) is suggested for the cleavage of the lactyl ether bond of MurNAc 6-phosphate, with the formation of an alpha,beta-unsaturated aldehyde intermediate with (E)-stereochemistry, followed by the syn addition of water to give product.
messages: Belongs to the GCKR-like family. MurNAc-6-P etherase subfamily.
messages: Homodimer.
messages: Induced by MurNAc 6-phosphate that releases the repressor MurR from the DNA. Repressed by MurR in the absence of MurNAc 6-phosphate.
messages: Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D-lactate. Together with AnmK, is also required for the utilization of anhydro-N-acetylmuramic acid (anhMurNAc) either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling.

230089:VY86 RS21520
gene id: 230089:VY86_RS21520
uniprot id: A0A0F7LSB3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type III secretion exporter family.
messages: Cell membrane
messages: Membrane
messages: Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

230089:VY86 RS10635
gene id: 230089:VY86_RS10635
uniprot id: A0A0F7LME0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptF/LptG family.
messages: Cell inner membrane
messages: Component of the lipopolysaccharide transport and assembly complex. The LptBFG transporter is composed of two ATP-binding proteins (LptB) and two transmembrane proteins (LptF and LptG).
messages: Membrane
messages: Part of the ABC transporter complex LptBFG involved in the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane.

230089:VY86 RS18970
gene id: 230089:VY86_RS18970
uniprot id: A0A0F7LR97
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 5 family.
messages: Periplasm

230089:VY86 RS21195
gene id: 230089:VY86_RS21195
uniprot id: A0A0F7LS66
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FliT family.
messages: Dual-function protein that regulates the transcription of class 2 flagellar operons and that also acts as an export chaperone for the filament-capping protein FliD. As a transcriptional regulator, acts as an anti-FlhDC factor; it directly binds FlhC, thus inhibiting the binding of the FlhC/FlhD complex to class 2 promoters, resulting in decreased expression of class 2 flagellar operons. As a chaperone, effects FliD transition to the membrane by preventing its premature polymerization, and by directing it to the export apparatus.
messages: Homodimer. Interacts with FliD and FlhC.
messages: cytosol

230089:VY86 RS17895
gene id: 230089:VY86_RS17895
uniprot id: A0A0F7LSW0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0756 family.
messages: Cell membrane

230089:VY86 RS11980
gene id: 230089:VY86_RS11980
uniprot id: A0A0F7LPD8
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.
messages: In the N-terminal section; belongs to the transposase 2 family.

230089:VY86 RS07915
gene id: 230089:VY86_RS07915
uniprot id: A0A0F7LMK7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SelA family.
messages: Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers. Binds only one seryl-tRNA(Sec) per dimer.

230089:VY86 RS15240
gene id: 230089:VY86_RS15240
uniprot id: A0A0F7LRV4
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

230089:VY86 RS07705
gene id: 230089:VY86_RS07705
uniprot id: A0A0F7LJH3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S-adenosyl-L-methionine to the 2'-OH of the wobble nucleotide.

230089:VY86 RS16320
gene id: 230089:VY86_RS16320
uniprot id: A0A0F7LQ34
names: Similarity
messages: Belongs to the catalase family.

230089:VY86 RS06220
gene id: 230089:VY86_RS06220
uniprot id: A0A0F7LLM9
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

230089:VY86 RS01415
gene id: 230089:VY86_RS01415
uniprot id: A0A0F7LJD8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AzlC family.
messages: Membrane

230089:VY86 RS18460
gene id: 230089:VY86_RS18460
uniprot id: A0A0F7LT53
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A highly abundant outer membrane lipoprotein that controls the distance between the inner and outer membranes. The only protein known to be covalently linked to the peptidoglycan network (PGN). Also non-covalently binds the PGN. The link between the cell outer membrane and PGN contributes to maintenance of the structural and functional integrity of the cell envelope, and maintains the correct distance between the PGN and the outer membrane.
messages: Belongs to the Lpp family.
messages: Cell outer membrane
messages: Homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: cell wall

230089:VY86 RS18965
gene id: 230089:VY86_RS18965
uniprot id: A0A0F7LPG2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 5 family.
messages: Periplasm

230089:VY86 RS06580
gene id: 230089:VY86_RS06580
uniprot id: A0A0F7LIV1
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

230089:VY86 RS18235
gene id: 230089:VY86_RS18235
uniprot id: A0A0F7LT13
names: Similarity
messages: Belongs to the peptidase C40 family.

230089:VY86 RS17490
gene id: 230089:VY86_RS17490
uniprot id: A0A0F7LNE9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

230089:VY86 RS19020
gene id: 230089:VY86_RS19020
uniprot id: A0A0F7LPG6
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

230089:VY86 RS17450
gene id: 230089:VY86_RS17450
uniprot id: A0A0F7LSF8
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.

230089:VY86 RS04580
gene id: 230089:VY86_RS04580
uniprot id: A0A0F7LLP5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

230089:VY86 RS12000
gene id: 230089:VY86_RS12000
uniprot id: A0A0F7LMZ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

230089:VY86 RS19095
gene id: 230089:VY86_RS19095
uniprot id: A0A0F7LTB2
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

230089:VY86 RS00800
gene id: 230089:VY86_RS00800
uniprot id: A0A0F7LJ71
names: Similarity
messages: Belongs to the peptidase M17 family.

230089:VY86 RS18015
gene id: 230089:VY86_RS18015
uniprot id: A0A0F7LQW7
names: Subcellular Location Annotation
messages: Membrane

230089:VY86 RS01095
gene id: 230089:VY86_RS01095
uniprot id: A0A0F7LJX2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RTX toxin acyltransferase family.
messages: Cytoplasm
messages: Involved in fatty acylation of protoxin at internal lysine residues, thereby converting it to the active toxin.

230089:VY86 RS15445
gene id: 230089:VY86_RS15445
uniprot id: A0A0F7LRS8
names: Similarity
messages: Belongs to the UPF0053 family.

230089:VY86 RS05265
gene id: 230089:VY86_RS05265
uniprot id: A0A0F7LI99
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DeoC/FbaB aldolase family. DeoC type 2 subfamily.
messages: Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
messages: Cytoplasm

230089:VY86 RS17460
gene id: 230089:VY86_RS17460
uniprot id: A0A0F7LSG6
names: Similarity
messages: Belongs to the GppA/Ppx family.

230089:VY86 RS15270
gene id: 230089:VY86_RS15270
uniprot id: A0A0F7LR89
names: Function
names: Similarity
messages: Belongs to the Dus family. DusC subfamily.
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U16 in tRNAs.

230089:VY86 RS01560
gene id: 230089:VY86_RS01560
uniprot id: A0A0F7LGE5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. SRP is a ribonucleoprotein composed of Ffh and a 4.5S RNA molecule.

230089:VY86 RS10575
gene id: 230089:VY86_RS10575
uniprot id: A0A0F7LNU2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RraB family.
messages: Cytoplasm
messages: Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome.
messages: Interacts with the C-terminal region of Rne.

230089:VY86 RS17380
gene id: 230089:VY86_RS17380
uniprot id: A0A0F7LQH4
names: Subcellular Location Annotation
messages: Cytoplasm

230089:VY86 RS14975
gene id: 230089:VY86_RS14975
uniprot id: A0A0F7LR48
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.
messages: Repressed under conditions of excess protein secretion capacity and derepressed when protein secretion becomes limiting. This is regulated by SecM.

230089:VY86 RS04795
gene id: 230089:VY86_RS04795
uniprot id: A0A0F7LJF8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm

230089:VY86 RS00495
gene id: 230089:VY86_RS00495
uniprot id: A0A0F7LJ06
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Reduced FMN (FMNH(2)).

230089:VY86 RS13710
gene id: 230089:VY86_RS13710
uniprot id: A0A0F7LNU0
names: Domain
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.
messages: The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate.

230089:VY86 RS05010
gene id: 230089:VY86_RS05010
uniprot id: A0A0F7LUX0
names: Cofactor
names: Similarity
messages: Belongs to the galactose-1-phosphate uridylyltransferase type 1 family.
messages: Binds 1 zinc ion per subunit.

230089:VY86 RS16835
gene id: 230089:VY86_RS16835
uniprot id: A0A0F7LN66
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial microcompartment
messages: Belongs to the EutB family.
messages: Binds between the large and small subunits.
messages: Catalyzes the deamination of various vicinal amino-alcohols to oxo compounds. Allows this organism to utilize ethanolamine as the sole source of nitrogen and carbon in the presence of vitamin B12.
messages: The basic unit is a heterodimer which dimerizes to form tetramers. The heterotetramers trimerize; 6 large subunits form a core ring with 6 small subunits projecting outwards.

230089:VY86 RS22365
gene id: 230089:VY86_RS22365
uniprot id: A0A0F7LKF9
names: Similarity
messages: Belongs to the VgrG protein family.

230089:VY86 RS22185
gene id: 230089:VY86_RS22185
uniprot id: A0A0F7LUW4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Gram-negative porin family.
messages: Cell outer membrane
messages: Membrane

230089:VY86 RS01645
gene id: 230089:VY86_RS01645
uniprot id: A0A0F7LV07
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm

230089:VY86 RS19030
gene id: 230089:VY86_RS19030
uniprot id: A0A0F7LTC3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Membrane

230089:VY86 RS02830
gene id: 230089:VY86_RS02830
uniprot id: A0A0F7LK21
names: Similarity
messages: Belongs to the P(II) protein family.

230089:VY86 RS16770
gene id: 230089:VY86_RS16770
uniprot id: A0A0F7LS12
names: Caution
names: Function
names: Similarity
messages: Belongs to the CobB/CobQ family. CobQ subfamily.
messages: Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

230089:VY86 RS14825
gene id: 230089:VY86_RS14825
uniprot id: A0A0F7LP85
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

230089:VY86 RS09125
gene id: 230089:VY86_RS09125
uniprot id: A0A0F7LNR9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptide transporter carbon starvation (CstA) (TC 2.A.114) family.
messages: Membrane

230089:VY86 RS03900
gene id: 230089:VY86_RS03900
uniprot id: A0A0F7LL43
names: Similarity
messages: In the N-terminal section; belongs to the CRISPR-associated nuclease Cas3-HD family.
messages: In the central section; belongs to the CRISPR-associated helicase Cas3 family.

230089:VY86 RS11475
gene id: 230089:VY86_RS11475
uniprot id: A0A0F7LP56
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KdpC family.
messages: Cell membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

230089:VY86 RS20630
gene id: 230089:VY86_RS20630
uniprot id: A0A0F7LRS6
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

230089:VY86 RS08880
gene id: 230089:VY86_RS08880
uniprot id: A0A0F7LN54
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S54 family.
messages: Cell membrane
messages: Membrane
messages: Rhomboid-type serine protease that catalyzes intramembrane proteolysis.

230089:VY86 RS04755
gene id: 230089:VY86_RS04755
uniprot id: A0A0F7LL54
names: Subcellular Location Annotation
messages: Membrane

230089:VY86 RS03115
gene id: 230089:VY86_RS03115
uniprot id: A0A0F7LKY2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LpxH family.
messages: Binds 2 Mn(2+) ions per subunit in a binuclear metal center.
messages: Cell inner membrane
messages: Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

230089:VY86 RS00910
gene id: 230089:VY86_RS00910
uniprot id: A0A0F7LHK1
names: Subcellular Location Annotation
messages: Membrane

230089:VY86 RS18005
gene id: 230089:VY86_RS18005
uniprot id: A0A0F7LSW6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0266 family.
messages: Cell membrane
messages: Membrane

230089:VY86 RS06830
gene id: 230089:VY86_RS06830
uniprot id: A0A0F7LMT6
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

230089:VY86 RS18040
gene id: 230089:VY86_RS18040
uniprot id: A0A0F7LNU9
names: Similarity
messages: Belongs to the UPF0181 family.

230089:VY86 RS20595
gene id: 230089:VY86_RS20595
uniprot id: A0A0F7LQ77
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial luciferase oxidoreductase family.
messages: Heterodimer of an alpha and a beta chain.
messages: Light-emitting reaction in luminous bacteria.

230089:VY86 RS02995
gene id: 230089:VY86_RS02995
uniprot id: A0A0F7LK49
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

230089:VY86 RS19055
gene id: 230089:VY86_RS19055
uniprot id: A0A0F7LRA8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

230089:VY86 RS16310
gene id: 230089:VY86_RS16310
uniprot id: A0A0F7LRR5
names: Function
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family. MenC type 1 subfamily.
messages: Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC) to 2-succinylbenzoate (OSB).

230089:VY86 RS03025
gene id: 230089:VY86_RS03025
uniprot id: A0A0F7LH49
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

230089:VY86 RS12450
gene id: 230089:VY86_RS12450
uniprot id: A0A0F7LPN2
names: Similarity
messages: Belongs to the transposase 11 family.

230089:VY86 RS10565
gene id: 230089:VY86_RS10565
uniprot id: A0A0F7LPE0
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

230089:VY86 RS07650
gene id: 230089:VY86_RS07650
uniprot id: A0A0F7LN30
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

230089:VY86 RS10610
gene id: 230089:VY86_RS10610
uniprot id: A0A0F7LMD5
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

230089:VY86 RS09230
gene id: 230089:VY86_RS09230
uniprot id: A0A0F7LLN8
names: Similarity
messages: Belongs to the RelB/DinJ antitoxin family.

230089:VY86 RS10275
gene id: 230089:VY86_RS10275
uniprot id: A0A0F7LNQ9
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

230089:VY86 RS12925
gene id: 230089:VY86_RS12925
uniprot id: A0A0F7LQB9
names: Subcellular Location Annotation
messages: Membrane

230089:VY86 RS05565
gene id: 230089:VY86_RS05565
uniprot id: A0A0F7LLX3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm

230089:VY86 RS05685
gene id: 230089:VY86_RS05685
uniprot id: A0A0F7LLH7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endonuclease V family.
messages: Cytoplasm
messages: DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA.

230089:VY86 RS12005
gene id: 230089:VY86_RS12005
uniprot id: A0A0F7LPW4
names: Similarity
messages: Belongs to the prokaryotic GSH synthase family.

230089:VY86 RS03565
gene id: 230089:VY86_RS03565
uniprot id: A0A0F7LKK2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).
messages: Homodimer.

230089:VY86 RS13675
gene id: 230089:VY86_RS13675
uniprot id: A0A0F7LQB6
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Bcr/CmlA family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

230089:VY86 RS06720
gene id: 230089:VY86_RS06720
uniprot id: A0A0F7LMH6
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

230089:VY86 RS15205
gene id: 230089:VY86_RS15205
uniprot id: A0A0F7LPJ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gluconeogenesis factor family.
messages: Cytoplasm
messages: Required for morphogenesis under gluconeogenic growth conditions.

230089:VY86 RS15050
gene id: 230089:VY86_RS15050
uniprot id: A0A0F7LR62
names: Function
messages: Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).

230089:VY86 RS19630
gene id: 230089:VY86_RS19630
uniprot id: A0A0F7LTM2
names: Similarity
messages: Belongs to the arginase family.

230089:VY86 RS20640
gene id: 230089:VY86_RS20640
uniprot id: A0A0F7LUA1
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

230089:VY86 RS14380
gene id: 230089:VY86_RS14380
uniprot id: A0A0F7LRD3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ExbD/TolR family.
messages: Cell inner membrane
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity. Required, with TolQ, for the proton motive force-dependent activation of TolA and for TolA-Pal interaction.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

230089:VY86 RS06200
gene id: 230089:VY86_RS06200
uniprot id: S4WCH2
names: Similarity
messages: Belongs to the NodU/CmcH family.

230089:VY86 RS02410
gene id: 230089:VY86_RS02410
uniprot id: A0A0F7LGU6
names: Subcellular Location Annotation
messages: Cytoplasm

230089:VY86 RS05970
gene id: 230089:VY86_RS05970
uniprot id: A0A0F7LIH1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DsrH/TusB family.
messages: Cytoplasm
messages: Heterohexamer, formed by a dimer of trimers. The hexameric TusBCD complex contains 2 copies each of TusB, TusC and TusD. The TusBCD complex interacts with TusE.
messages: Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions.

230089:VY86 RS05285
gene id: 230089:VY86_RS05285
uniprot id: A0A0F7LLE4
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

230089:VY86 RS01245
gene id: 230089:VY86_RS01245
uniprot id: A0A0F7LGA7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

230089:VY86 RS19940
gene id: 230089:VY86_RS19940
uniprot id: A0A0F7LTQ3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dethiobiotin synthetase family.
messages: Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

230089:VY86 RS20280
gene id: 230089:VY86_RS20280
uniprot id: A0A0F7LTW4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase D family.
messages: Cytoplasm
messages: Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides.

230089:VY86 RS16780
gene id: 230089:VY86_RS16780
uniprot id: A0A0F7LQC1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobS family.
messages: Cell membrane
messages: Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.
messages: Membrane

230089:VY86 RS05760
gene id: 230089:VY86_RS05760
uniprot id: A0A0F7LLZ9
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

230089:VY86 RS19430
gene id: 230089:VY86_RS19430
uniprot id: A0A0F7LTT7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenosine deaminase subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolytic deamination of adenosine and 2-deoxyadenosine.

230089:VY86 RS12330
gene id: 230089:VY86_RS12330
uniprot id: A0A0F7LPN2
names: Similarity
messages: Belongs to the transposase 11 family.

230089:VY86 RS20975
gene id: 230089:VY86_RS20975
uniprot id: A0A0F7LUA7
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

230089:VY86 RS00995
gene id: 230089:VY86_RS00995
uniprot id: A0A0F7LHL2
names: Similarity
messages: Belongs to the VgrG protein family.

230089:VY86 RS20380
gene id: 230089:VY86_RS20380
uniprot id: A0A0F7LU77
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LpxL/LpxM/LpxP family. LpxM subfamily.
messages: Catalyzes the transfer of an acyl chain from an acyl-[acyl-carrier-protein] (ACP) to a Kdo(2)-(acyl)-lipid IV(A) to form a Kdo(2)-lipid A.
messages: Cell inner membrane

230089:VY86 RS05675
gene id: 230089:VY86_RS05675
uniprot id: A0A0F7LLZ6
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

230089:VY86 RS00685
gene id: 230089:VY86_RS00685
uniprot id: A0A0F7LJX3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic sulfate-binding protein family.
messages: Periplasm

230089:VY86 RS06990
gene id: 230089:VY86_RS06990
uniprot id: A0A0F7LJ26
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic pantothenate kinase family.
messages: Cytoplasm

230089:VY86 RS04190
gene id: 230089:VY86_RS04190
uniprot id: A0A0F7LHR8
names: Cofactor
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.
messages: Binds 1 zinc ion per subunit.

230089:VY86 RS04730
gene id: 230089:VY86_RS04730
uniprot id: A0A0F7LL50
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

230089:VY86 RS05785
gene id: 230089:VY86_RS05785
uniprot id: A0A0F7LM01
names: Similarity
messages: Belongs to the YoeB family.

230089:VY86 RS03805
gene id: 230089:VY86_RS03805
uniprot id: A0A0F7LST9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HesB/IscA family.
messages: Binds 1 iron-sulfur cluster per subunit.
messages: Homodimer.
messages: Required for insertion of 4Fe-4S clusters for at least IspG.

230089:VY86 RS03550
gene id: 230089:VY86_RS03550
uniprot id: A0A0F7LIT4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SurE nucleotidase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Cytoplasm
messages: Nucleotidase with a broad substrate specificity as it can dephosphorylate various ribo- and deoxyribonucleoside 5'-monophosphates and ribonucleoside 3'-monophosphates with highest affinity to 3'-AMP. Also hydrolyzes polyphosphate (exopolyphosphatase activity) with the preference for short-chain-length substrates (P20-25). Might be involved in the regulation of dNTP and NTP pools, and in the turnover of 3'-mononucleotides produced by numerous intracellular RNases (T1, T2, and F) during the degradation of various RNAs.

230089:VY86 RS01130
gene id: 230089:VY86_RS01130
uniprot id: A0A0F7LK43
names: Function
names: Similarity
messages: Belongs to the flavodoxin family.
messages: Low-potential electron donor to a number of redox enzymes.

230089:VY86 RS21035
gene id: 230089:VY86_RS21035
uniprot id: A0A0F7LUB3
names: Similarity
messages: Belongs to the VgrG protein family.

230089:VY86 RS21415
gene id: 230089:VY86_RS21415
uniprot id: A0A0F7LUK6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
messages: Bacterial flagellum basal body
messages: Belongs to the FlgI family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod.

230089:VY86 RS09085
gene id: 230089:VY86_RS09085
uniprot id: A0A0F7LNQ5
names: Similarity
messages: Belongs to the RelE toxin family.

230089:VY86 RS13725
gene id: 230089:VY86_RS13725
uniprot id: A0A0F7LQC3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Membrane

230089:VY86 RS01885
gene id: 230089:VY86_RS01885
uniprot id: A0A0F7LK87
names: Similarity
messages: Belongs to the ribosome association toxin RatA family.

230089:VY86 RS04410
gene id: 230089:VY86_RS04410
uniprot id: A0A0F7LKX3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
messages: Homodimer.

230089:VY86 RS05330
gene id: 230089:VY86_RS05330
uniprot id: A0A0F7LJL3
names: Similarity
messages: Belongs to the transglycosylase Slt family.

230089:VY86 RS01070
gene id: 230089:VY86_RS01070
uniprot id: A0A0F7LK38
names: Similarity
messages: Belongs to the VgrG protein family.

230089:VY86 RS03065
gene id: 230089:VY86_RS03065
uniprot id: A0A0F7LKV4
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

230089:VY86 RS05190
gene id: 230089:VY86_RS05190
uniprot id: A0A0F7LLX5
names: Similarity
messages: Belongs to the NodU/CmcH family.

230089:VY86 RS05660
gene id: 230089:VY86_RS05660
uniprot id: A0A0F7LLH2
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

230089:VY86 RS15000
gene id: 230089:VY86_RS15000
uniprot id: A0A0F7LR51
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Cell inner membrane
messages: Membrane

230089:VY86 RS14985
gene id: 230089:VY86_RS14985
uniprot id: A0A0F7LPC7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA gyrase inhibitor YacG family.
messages: Binds 1 zinc ion.
messages: Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase.
messages: Interacts with GyrB.

230089:VY86 RS17180
gene id: 230089:VY86_RS17180
uniprot id: A0A0F7LNB2
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. TatD-type hydrolase family.

230089:VY86 RS13025
gene id: 230089:VY86_RS13025
uniprot id: A0A0F7LLR2
names: Function
names: Similarity
messages: Belongs to the Dus family. DusB subfamily.
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

230089:VY86 RS03620
gene id: 230089:VY86_RS03620
uniprot id: A0A0F7LL71
names: Subcellular Location Annotation
messages: Membrane

230089:VY86 RS22060
gene id: 230089:VY86_RS22060
uniprot id: A0A0F7LSK7
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.
messages: In the N-terminal section; belongs to the transposase 2 family.

230089:VY86 RS13690
gene id: 230089:VY86_RS13690
uniprot id: A0A0F7LQS2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase class-III family.
messages: Binds 2 Fe(2+) ions per subunit.
messages: Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes.

230089:VY86 RS03030
gene id: 230089:VY86_RS03030
uniprot id: A0A0F7LIH7
names: Similarity
messages: Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily.

230089:VY86 RS13655
gene id: 230089:VY86_RS13655
uniprot id: A0A0F7LQR8
names: Similarity
messages: Belongs to the UPF0441 family.

230089:VY86 RS06270
gene id: 230089:VY86_RS06270
uniprot id: A0A0F7LK58
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

230089:VY86 RS18735
gene id: 230089:VY86_RS18735
uniprot id: A0A0F7LTI8
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

230089:VY86 RS06345
gene id: 230089:VY86_RS06345
uniprot id: A0A0F7LIS7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

230089:VY86 RS11950
gene id: 230089:VY86_RS11950
uniprot id: A0A0F7LQ38
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

230089:VY86 RS06895
gene id: 230089:VY86_RS06895
uniprot id: A0A0F7LJ16
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

230089:VY86 RS05445
gene id: 230089:VY86_RS05445
uniprot id: A0A0F7LIC2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

230089:VY86 RS19150
gene id: 230089:VY86_RS19150
uniprot id: A0A0F7LTQ8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LapA family.
messages: Cell inner membrane
messages: Involved in the assembly of lipopolysaccharide (LPS).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

230089:VY86 RS19005
gene id: 230089:VY86_RS19005
uniprot id: A0A0F7LTC2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phospholipase D family. Cardiolipin synthase subfamily. ClsA sub-subfamily.
messages: Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol.
messages: Cell membrane
messages: Membrane

230089:VY86 RS02905
gene id: 230089:VY86_RS02905
uniprot id: A0A0F7LK41
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

230089:VY86 RS17905
gene id: 230089:VY86_RS17905
uniprot id: A0A0F7LQU1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0370 family.
messages: Cell membrane

230089:VY86 RS02160
gene id: 230089:VY86_RS02160
uniprot id: A0A0F7LJQ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell inner membrane
messages: Membrane

230089:VY86 RS21825
gene id: 230089:VY86_RS21825
uniprot id: A0A0F7LUP8
names: Similarity
messages: Belongs to the MotB family.

230089:VY86 RS04940
gene id: 230089:VY86_RS04940
uniprot id: A0A0F7LV35
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

230089:VY86 RS17305
gene id: 230089:VY86_RS17305
uniprot id: A0A0F7LSD7
names: Similarity
names: Subunit
messages: Belongs to the Nudix hydrolase family. NudJ subfamily.
messages: Monomer.

230089:VY86 RS01540
gene id: 230089:VY86_RS01540
uniprot id: A0A0F7LHU8
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

230089:VY86 RS04355
gene id: 230089:VY86_RS04355
uniprot id: A0A0F7LHS8
names: Subcellular Location Annotation
messages: Cytoplasm

230089:VY86 RS14510
gene id: 230089:VY86_RS14510
uniprot id: A0A0F7LM88
names: Similarity
messages: Belongs to the UbiH/COQ6 family.

230089:VY86 RS10285
gene id: 230089:VY86_RS10285
uniprot id: A0A0F7LM47
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

230089:VY86 RS20740
gene id: 230089:VY86_RS20740
uniprot id: A0A0F7LU63
names: Similarity
messages: Belongs to the DapA family.

230089:VY86 RS00755
gene id: 230089:VY86_RS00755
uniprot id: A0A0F7LHH6
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity.

230089:VY86 RS18745
gene id: 230089:VY86_RS18745
uniprot id: A0A0F7LPE5
names: Function
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
messages: Catalyzes the oxidative phosphorylation of glyceraldehyde 3-phosphate (G3P) to 1,3-bisphosphoglycerate (BPG) using the cofactor NAD. The first reaction step involves the formation of a hemiacetal intermediate between G3P and a cysteine residue, and this hemiacetal intermediate is then oxidized to a thioester, with concomitant reduction of NAD to NADH. The reduced NADH is then exchanged with the second NAD, and the thioester is attacked by a nucleophilic inorganic phosphate to produce BPG.

230089:VY86 RS02835
gene id: 230089:VY86_RS02835
uniprot id: A0A0F7LH19
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

230089:VY86 RS18575
gene id: 230089:VY86_RS18575
uniprot id: A0A0F7LT69
names: Function
names: Similarity
names: Subunit
messages: Belongs to the pyridoxine kinase family. PdxY subfamily.
messages: Homodimer.
messages: Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP.

230089:VY86 RS02610
gene id: 230089:VY86_RS02610
uniprot id: A0A0F7LKL5
names: Similarity
messages: Belongs to the transglycosylase Slt family.

230089:VY86 RS18095
gene id: 230089:VY86_RS18095
uniprot id: A0A0F7LQX7
names: Similarity
messages: Belongs to the peptidase S41A family.

230089:VY86 RS13405
gene id: 230089:VY86_RS13405
uniprot id: A0A0F7LNS3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

230089:VY86 RS14995
gene id: 230089:VY86_RS14995
uniprot id: A0A0F7LRR6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

230089:VY86 RS07200
gene id: 230089:VY86_RS07200
uniprot id: A0A0F7LJ51
names: Similarity
messages: Belongs to the ferredoxin--NADP reductase type 1 family.

230089:VY86 RS11500
gene id: 230089:VY86_RS11500
uniprot id: A0A0F7LV82
names: Function
names: Similarity
messages: Belongs to the transposase 11 family.
messages: Involved in the transposition of the insertion sequence IS5.

230089:VY86 RS02485
gene id: 230089:VY86_RS02485
uniprot id: A0A0F7LI34
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YajC family.
messages: Cell inner membrane
messages: Membrane

230089:VY86 RS15300
gene id: 230089:VY86_RS15300
uniprot id: A0A0F7LR93
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the helicase family. DinG subfamily. Type 1 sub-subfamily.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA-dependent ATPase and 5'-3' DNA helicase.

230089:VY86 RS11900
gene id: 230089:VY86_RS11900
uniprot id: A0A0F7LQ20
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ApbE family.
messages: Cell inner membrane
messages: Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein.
messages: Magnesium. Can also use manganese.

230089:VY86 RS03715
gene id: 230089:VY86_RS03715
uniprot id: A0A0F7LKP0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell inner membrane
messages: Membrane

230089:VY86 RS17030
gene id: 230089:VY86_RS17030
uniprot id: A0A0F7LSA9
names: Subcellular Location Annotation
messages: Membrane

230089:VY86 RS15180
gene id: 230089:VY86_RS15180
uniprot id: A0A0F7LPI7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dethiobiotin synthetase family.
messages: Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

230089:VY86 RS06605
gene id: 230089:VY86_RS06605
uniprot id: A0A0F7LIW6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.

230089:VY86 RS10840
gene id: 230089:VY86_RS10840
uniprot id: A0A0F7LNY9
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

230089:VY86 RS20795
gene id: 230089:VY86_RS20795
uniprot id: A0A0F7LRV6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal stress protein A family.
messages: Cytoplasm

230089:VY86 RS01255
gene id: 230089:VY86_RS01255
uniprot id: A0A0F7LJY1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CN hydrolase family. Apolipoprotein N-acyltransferase subfamily.
messages: Catalyzes the phospholipid dependent N-acylation of the N-terminal cysteine of apolipoprotein, the last step in lipoprotein maturation.
messages: Cell membrane
messages: Membrane

230089:VY86 RS11050
gene id: 230089:VY86_RS11050
uniprot id: A0A0F7LKV3
names: Similarity
messages: Belongs to the gluconokinase GntK/GntV family.

230089:VY86 RS20125
gene id: 230089:VY86_RS20125
uniprot id: A0A0F7LPY9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UreF family.
messages: Cytoplasm
messages: Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
messages: UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

230089:VY86 RS04910
gene id: 230089:VY86_RS04910
uniprot id: A0A0F7LL74
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.
messages: Homodimer.

230089:VY86 RS03580
gene id: 230089:VY86_RS03580
uniprot id: A0A0F7LIT8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.
messages: Heterodimer composed of CysD, the smaller subunit, and CysN.
messages: With CysD forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway. APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD.

230089:VY86 RS21085
gene id: 230089:VY86_RS21085
uniprot id: A0A0F7LQD5
names: Subcellular Location Annotation
messages: Membrane

230089:VY86 RS18450
gene id: 230089:VY86_RS18450
uniprot id: A0A0F7LT52
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SufE family.
messages: Cytoplasm
messages: Homodimer. Interacts with SufS.
messages: Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process.

230089:VY86 RS18775
gene id: 230089:VY86_RS18775
uniprot id: A0A0F7LR80
names: Cofactor
names: Similarity
messages: Belongs to the nitroreductase family.
messages: Binds 1 FMN per subunit.

230089:VY86 RS12515
gene id: 230089:VY86_RS12515
uniprot id: A0A0F7LLH1
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

230089:VY86 RS10310
gene id: 230089:VY86_RS10310
uniprot id: A0A0F7LM50
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.
messages: Cytoplasm
messages: Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.

230089:VY86 RS14930
gene id: 230089:VY86_RS14930
uniprot id: A0A0F7LPA7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).

230089:VY86 RS00555
gene id: 230089:VY86_RS00555
uniprot id: A0A0F7LHE4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OmpP1/FadL family.
messages: Cell outer membrane
messages: Membrane

230089:VY86 RS01920
gene id: 230089:VY86_RS01920
uniprot id: A0A0F7LKC6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
messages: Cytoplasm
messages: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.

230089:VY86 RS14130
gene id: 230089:VY86_RS14130
uniprot id: A0A0F7LRA1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the isocitrate lyase/PEP mutase superfamily. Methylisocitrate lyase family.
messages: Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate.
messages: Homotetramer; dimer of dimers.
messages: Involved in the catabolism of short chain fatty acids (SCFA) via the 2-methylcitrate cycle (propionate degradation route). Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate via an alpha-carboxy-carbanion intermediate.

230089:VY86 RS17980
gene id: 230089:VY86_RS17980
uniprot id: A0A0F7LJK6
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

230089:VY86 RS01605
gene id: 230089:VY86_RS01605
uniprot id: A0A0F7LGE8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Mediates global changes in gene expression, shifting from rapid growth to stress survival by linking envelope stress, the stringent response and the catabolite repression systems. Usually binds in the 5'-UTR; binding at or near the Shine-Dalgarno sequence prevents ribosome-binding, repressing translation, binding elsewhere in the 5'-UTR can activate translation and/or stabilize the mRNA. Its function is antagonized by small RNA(s).
messages: Belongs to the CsrA/RsmA family.
messages: Cytoplasm
messages: Homodimer; the beta-strands of each monomer intercalate to form a hydrophobic core, while the alpha-helices form wings that extend away from the core.

230089:VY86 RS10145
gene id: 230089:VY86_RS10145
uniprot id: A0A0F7LPB4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RlmJ family.
messages: Monomer.
messages: Specifically methylates the adenine in position 2030 of 23S rRNA.

230089:VY86 RS10925
gene id: 230089:VY86_RS10925
uniprot id: A0A0F7LPI9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiJ family.
messages: Cytoplasm
messages: Required for ubiquinone (coenzyme Q) biosynthesis. Binds hydrophobic ubiquinone biosynthetic intermediates via its SCP2 domain and is essential for the stability of the Ubi complex. May constitute a docking platform where Ubi enzymes assemble and access their SCP2-bound polyprenyl substrates.

230089:VY86 RS14925
gene id: 230089:VY86_RS14925
uniprot id: A0A0F7LME6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEDS family. FtsW subfamily.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Peptidoglycan polymerase that is essential for cell division.

230089:VY86 RS18425
gene id: 230089:VY86_RS18425
uniprot id: A0A0F7LT48
names: Similarity
messages: Belongs to the HesB/IscA family.

230089:VY86 RS04110
gene id: 230089:VY86_RS04110
uniprot id: A0A0F7LHQ3
names: Similarity
names: Subunit
messages: Belongs to the beta-eliminating lyase family.
messages: Homotetramer.

230089:VY86 RS21205
gene id: 230089:VY86_RS21205
uniprot id: A0A0F7LUN0
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliE family.

230089:VY86 RS00965
gene id: 230089:VY86_RS00965
uniprot id: A0A0F7LHK8
names: Similarity
messages: Belongs to the transposase 11 family.

230089:VY86 RS07745
gene id: 230089:VY86_RS07745
uniprot id: A0A0F7LN38
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA.
messages: Homodimer.

230089:VY86 RS14815
gene id: 230089:VY86_RS14815
uniprot id: A0A0F7LR24
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.

230089:VY86 RS14445
gene id: 230089:VY86_RS14445
uniprot id: A0A0F7LM81
names: Cofactor
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cell inner membrane
messages: Membrane
messages: Membrane-anchoring subunit of succinate dehydrogenase (SDH).
messages: Part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur protein, plus two membrane-anchoring proteins, SdhC and SdhD.
messages: The heme is bound between the two transmembrane subunits.

230089:VY86 RS08375
gene id: 230089:VY86_RS08375
uniprot id: A0A0F7LJS9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits).
messages: In the C-terminal section; belongs to the transpeptidase family.
messages: In the N-terminal section; belongs to the glycosyltransferase 51 family.
messages: Membrane

230089:VY86 RS14800
gene id: 230089:VY86_RS14800
uniprot id: A0A0F7LP82
names: Caution
names: Function
messages: Activates the small RNA gene sgrS under glucose-phosphate stress conditions as well as yfdZ. Represses its own transcription under both stress and non-stress conditions. Might act as a sensor of the intracellular accumulation of phosphoglucose by binding these molecules in its C-terminal solute-binding domain.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

230089:VY86 RS02705
gene id: 230089:VY86_RS02705
uniprot id: A0A0F7LH01
names: Similarity
messages: Belongs to the UPF0234 family.

230089:VY86 RS05975
gene id: 230089:VY86_RS05975
uniprot id: A0A0F7LJY4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DsrF/TusC family.
messages: Cytoplasm
messages: Heterohexamer, formed by a dimer of trimers. The hexameric TusBCD complex contains 2 copies each of TusB, TusC and TusD. The TusBCD complex interacts with TusE.
messages: Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions.

230089:VY86 RS11170
gene id: 230089:VY86_RS11170
uniprot id: A0A0F7LMM3
names: Similarity
messages: Belongs to the Rpn/YhgA-like nuclease family.

230089:VY86 RS01280
gene id: 230089:VY86_RS01280
uniprot id: A0A0F7LJY6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Membrane

230089:VY86 RS14195
gene id: 230089:VY86_RS14195
uniprot id: A0A0F7LQZ9
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerD subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD, in which XerC interacts with XerD via its C-terminal region, XerD interacts with XerC via its C-terminal region and so on.
messages: FtsK may regulate the catalytic switch between XerC and XerD in the heterotetrameric complex during the two steps of the recombination process.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. Binds cooperatively to specific DNA consensus sequences that are separated from XerC binding sites by a short central region, forming the heterotetrameric XerC-XerD complex that recombines DNA substrates. The complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids. In the complex XerD specifically exchanges the bottom DNA strands.

230089:VY86 RS02360
gene id: 230089:VY86_RS02360
uniprot id: A0A0F7LI09
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial secretin family. T3SS SctC subfamily.
messages: Cell outer membrane
messages: Component of the type III secretion system (T3SS), also called injectisome, which is used to inject bacterial effector proteins into eukaryotic host cells. Forms a ring-shaped multimeric structure with an apparent central pore in the outer membrane.
messages: Membrane
messages: The core secretion machinery of the T3SS is composed of approximately 20 different proteins, including cytoplasmic components, a base, an export apparatus and a needle. This subunit is part of the base, which anchors the injectisome in the bacterial cell envelope. Forms a stable homooligomeric complex.

230089:VY86 RS04085
gene id: 230089:VY86_RS04085
uniprot id: A0A0F7LL96
names: Cofactor
names: Function
messages: Binds 4 [4Fe-4S] clusters per subunit.
messages: The beta chain is an electron transfer unit containing 4 cysteine clusters involved in the formation of iron-sulfur centers.

230089:VY86 RS05200
gene id: 230089:VY86_RS05200
uniprot id: A0A0F7LI80
names: Subcellular Location Annotation
messages: Membrane

230089:VY86 RS07855
gene id: 230089:VY86_RS07855
uniprot id: A0A0F7LN76
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.

230089:VY86 RS04850
gene id: 230089:VY86_RS04850
uniprot id: A0A0F7LLJ0
names: Domain
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cell inner membrane
messages: Homodimer.
messages: Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB/RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host.
messages: The transmembrane domain is a dimerization domain.

230089:VY86 RS05620
gene id: 230089:VY86_RS05620
uniprot id: A0A0F7LJR2
names: Cofactor
messages: Can also use Mn(2+) ion.

230089:VY86 RS09515
gene id: 230089:VY86_RS09515
uniprot id: A0A0F7LNI7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

230089:VY86 RS03830
gene id: 230089:VY86_RS03830
uniprot id: A0A0F7LKP8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PNP/UDP phosphorylase family. MtnN subfamily.
messages: Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively. Also cleaves 5'-deoxyadenosine, a toxic by-product of radical S-adenosylmethionine (SAM) enzymes, into 5-deoxyribose and adenine. Thus, is required for in vivo function of the radical SAM enzymes biotin synthase and lipoic acid synthase, that are inhibited by 5'-deoxyadenosine accumulation.
messages: Homodimer.

230089:VY86 RS00110
gene id: 230089:VY86_RS00110
uniprot id: A0A0F7LFY4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinylarginine dihydrolase family.
messages: Catalyzes the hydrolysis of N(2)-succinylarginine into N(2)-succinylornithine, ammonia and CO(2).
messages: Homodimer.

230089:VY86 RS09135
gene id: 230089:VY86_RS09135
uniprot id: A0A0F7LN69
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

230089:VY86 RS06835
gene id: 230089:VY86_RS06835
uniprot id: A0A0F7LM20
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

230089:VY86 RS10185
gene id: 230089:VY86_RS10185
uniprot id: A0A0F7LM36
names: Subcellular Location Annotation
messages: Membrane

230089:VY86 RS18230
gene id: 230089:VY86_RS18230
uniprot id: A0A0F7LR16
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArnF family.
messages: Cell inner membrane
messages: Heterodimer of ArnE and ArnF.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Translocates 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol (alpha-L-Ara4N-phosphoundecaprenol) from the cytoplasmic to the periplasmic side of the inner membrane.

230089:VY86 RS09425
gene id: 230089:VY86_RS09425
uniprot id: A0A0F7LNG8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

230089:VY86 RS18010
gene id: 230089:VY86_RS18010
uniprot id: A0A0F7LNU6
names: Subcellular Location Annotation
messages: Membrane

230089:VY86 RS00125
gene id: 230089:VY86_RS00125
uniprot id: A0A0F7LJM6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in both the arginine and lysine biosynthetic pathways.

230089:VY86 RS21945
gene id: 230089:VY86_RS21945
uniprot id: A0A0F7LUV7
names: Similarity
messages: Belongs to the TPP enzyme family.

230089:VY86 RS02805
gene id: 230089:VY86_RS02805
uniprot id: A0A0F7LK20
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the QueC family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).

230089:VY86 RS21795
gene id: 230089:VY86_RS21795
uniprot id: A0A0F7LSG4
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CheB family.
messages: Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.
messages: Cytoplasm
messages: Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
messages: Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity.

230089:VY86 RS13600
gene id: 230089:VY86_RS13600
uniprot id: A0A0F7LQA8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DHBP synthase family.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Homodimer.

230089:VY86 RS12885
gene id: 230089:VY86_RS12885
uniprot id: A0A0F7LLQ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Organophosphate:Pi antiporter (OPA) (TC 2.A.1.4) family.
messages: Membrane

230089:VY86 RS16105
gene id: 230089:VY86_RS16105
uniprot id: A0A0F7LS08
names: Subcellular Location Annotation
messages: Membrane

230089:VY86 RS02500
gene id: 230089:VY86_RS02500
uniprot id: A0A0F7LJV6
names: Function
names: Similarity
messages: Belongs to the AcpH family.
messages: Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP.

230089:VY86 RS06725
gene id: 230089:VY86_RS06725
uniprot id: A0A0F7LMS8
names: Similarity
messages: Belongs to the UPF0438 family.

230089:VY86 RS20020
gene id: 230089:VY86_RS20020
uniprot id: A0A0F7LPX8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LigB/MhpB extradiol dioxygenase family.
messages: Catalyzes the non-heme iron(II)-dependent oxidative cleavage of 2,3-dihydroxyphenylpropionic acid and 2,3-dihydroxicinnamic acid into 2-hydroxy-6-ketononadienedioate and 2-hydroxy-6-ketononatrienedioate, respectively.
messages: Homotetramer.

230089:VY86 RS14970
gene id: 230089:VY86_RS14970
uniprot id: A0A0F7LRR2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecM family.
messages: Periplasm
messages: Regulates secA expression by translational coupling of the secM secA operon. Translational pausing at a specific Pro residue 5 residues before the end of the protein may allow disruption of a mRNA repressor helix that normally suppresses secA translation initiation.
messages: cytosol

230089:VY86 RS18150
gene id: 230089:VY86_RS18150
uniprot id: A0A0F7LQY2
names: Similarity
messages: Belongs to the transglycosylase Slt family.

230089:VY86 RS17430
gene id: 230089:VY86_RS17430
uniprot id: A0A0F7LST3
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. MdtC subfamily.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of a tripartite efflux system composed of MdtA, MdtB and MdtC. MdtC forms a heteromultimer with MdtB.

230089:VY86 RS18515
gene id: 230089:VY86_RS18515
uniprot id: A0A0F7LT64
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Bcr/CmlA family.
messages: Cell inner membrane
messages: Membrane

230089:VY86 RS19185
gene id: 230089:VY86_RS19185
uniprot id: A0A0F7LPL1
names: Similarity
messages: Belongs to the CcdB toxin family.

230089:VY86 RS14055
gene id: 230089:VY86_RS14055
uniprot id: A0A0F7LM40
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Slam family.
messages: Cell outer membrane
messages: Membrane

230089:VY86 RS18175
gene id: 230089:VY86_RS18175
uniprot id: A0A0F7LQY4
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

230089:VY86 RS00710
gene id: 230089:VY86_RS00710
uniprot id: A0A0F7LJN8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M4 family.
messages: Extracellular zinc metalloprotease.
messages: Secreted

230089:VY86 RS14450
gene id: 230089:VY86_RS14450
uniprot id: A0A0F7LP08
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome b560 family.
messages: Membrane
messages: Membrane-anchoring subunit of succinate dehydrogenase (SDH).
messages: Part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur protein, plus two membrane-anchoring proteins, SdhC and SdhD. The complex can form homotrimers.
messages: The heme is bound between the two transmembrane subunits.

230089:VY86 RS08535
gene id: 230089:VY86_RS08535
uniprot id: A0A0F7LPN2
names: Similarity
messages: Belongs to the transposase 11 family.

230089:VY86 RS07215
gene id: 230089:VY86_RS07215
uniprot id: A0A0F7LMZ2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

230089:VY86 RS22020
gene id: 230089:VY86_RS22020
uniprot id: A0A0F7LSK4
names: Similarity
messages: In the N-terminal section; belongs to the CRISPR-associated nuclease Cas3-HD family.
messages: In the central section; belongs to the CRISPR-associated helicase Cas3 family.

230089:VY86 RS02050
gene id: 230089:VY86_RS02050
uniprot id: A0A0F7LKA7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Membrane

230089:VY86 RS15760
gene id: 230089:VY86_RS15760
uniprot id: A0A0F7LRW7
names: Similarity
messages: Belongs to the asparaginase 1 family.

230089:VY86 RS12905
gene id: 230089:VY86_RS12905
uniprot id: A0A0F7LQ11
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sulfur carrier protein TusA family.
messages: Cytoplasm
messages: Interacts with IscS.
messages: Sulfur carrier protein involved in sulfur trafficking in the cell. Part of a sulfur-relay system required for 2-thiolation during synthesis of 2-thiouridine of the modified wobble base 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) in tRNA. Interacts with IscS and stimulates its cysteine desulfurase activity. Accepts an activated sulfur from IscS, which is then transferred to TusD, and thus determines the direction of sulfur flow from IscS to 2-thiouridine formation. Also appears to be involved in sulfur transfer for the biosynthesis of molybdopterin.

230089:VY86 RS17675
gene id: 230089:VY86_RS17675
uniprot id: A0A0F7LQK6
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

230089:VY86 RS20450
gene id: 230089:VY86_RS20450
uniprot id: A0A0F7LTZ1
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CutC family.
messages: Cytoplasm
messages: Once thought to be involved in copper homeostasis, experiments in E.coli have shown this is not the case.

230089:VY86 RS03735
gene id: 230089:VY86_RS03735
uniprot id: A0A0F7LL86
names: Function
names: Similarity
messages: Belongs to the HPPK family.
messages: Catalyzes the transfer of pyrophosphate from adenosine triphosphate (ATP) to 6-hydroxymethyl-7,8-dihydropterin, an enzymatic step in folate biosynthesis pathway.

230089:VY86 RS11415
gene id: 230089:VY86_RS11415
uniprot id: A0A0F7LMP3
names: Similarity
messages: Belongs to the phosphohexose mutase family.

230089:VY86 RS06010
gene id: 230089:VY86_RS06010
uniprot id: A0A0F7LMA9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family. KefB subfamily.
messages: Cell inner membrane
messages: Interacts with the regulatory subunit KefG.
messages: Pore-forming subunit of a potassium efflux system that confers protection against electrophiles. Catalyzes K(+)/H(+) antiport.

230089:VY86 RS16705
gene id: 230089:VY86_RS16705
uniprot id: A0A0F7LQA6
names: Function
names: Similarity
messages: Belongs to the CbiD family.
messages: Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A.

230089:VY86 RS09395
gene id: 230089:VY86_RS09395
uniprot id: A0A0F7LP03
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigB subfamily.
messages: Catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction.

230089:VY86 RS07805
gene id: 230089:VY86_RS07805
uniprot id: A0A0F7LMI5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

230089:VY86 RS14330
gene id: 230089:VY86_RS14330
uniprot id: A0A0F7LNZ4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nicotinamide ribonucleoside (NR) uptake permease (TC 4.B.1) family.
messages: Membrane
messages: Required for nicotinamide riboside transport across the inner membrane.

230089:VY86 RS04700
gene id: 230089:VY86_RS04700
uniprot id: A0A0F7LI04
names: Subcellular Location Annotation
messages: Membrane

230089:VY86 RS13455
gene id: 230089:VY86_RS13455
uniprot id: A0A0F7LNS6
names: Similarity
messages: In the N-terminal section; belongs to the NADH:flavin oxidoreductase/NADH oxidase family.

230089:VY86 RS05955
gene id: 230089:VY86_RS05955
uniprot id: A0A0F7LM34
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

230089:VY86 RS00370
gene id: 230089:VY86_RS00370
uniprot id: A0A0F7LJI3
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

230089:VY86 RS10235
gene id: 230089:VY86_RS10235
uniprot id: A0A0F7LM42
names: Subcellular Location Annotation
messages: Membrane

230089:VY86 RS02445
gene id: 230089:VY86_RS02445
uniprot id: A0A0F7LJU6
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG).

230089:VY86 RS13415
gene id: 230089:VY86_RS13415
uniprot id: A0A0F7LQT4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

230089:VY86 RS14390
gene id: 230089:VY86_RS14390
uniprot id: A0A0F7LM74
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

230089:VY86 RS14720
gene id: 230089:VY86_RS14720
uniprot id: A0A0F7LP69
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: In the N-terminal section; belongs to the FGAMS family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.

230089:VY86 RS07575
gene id: 230089:VY86_RS07575
uniprot id: A0A0F7LMD9
names: Similarity
messages: Belongs to the bacterial sugar transferase family.

230089:VY86 RS13540
gene id: 230089:VY86_RS13540
uniprot id: A0A0F7LVF9
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane
messages: Membrane

230089:VY86 RS18070
gene id: 230089:VY86_RS18070
uniprot id: A0A0F7LQX5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CopD family.
messages: Cell inner membrane
messages: Involved in copper resistance.
messages: Membrane

230089:VY86 RS07140
gene id: 230089:VY86_RS07140
uniprot id: A0A0F7LMX9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MetJ family.
messages: Cytoplasm
messages: Does not bind DNA by a helix-turn-helix motif.
messages: Homodimer.
messages: This regulatory protein, when combined with SAM (S-adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis.

230089:VY86 RS04390
gene id: 230089:VY86_RS04390
uniprot id: A0A0F7LUW3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamA family.
messages: Cell outer membrane
messages: Part of the Bam complex, which is composed of the outer membrane protein BamA, and four lipoproteins BamB, BamC, BamD and BamE.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. Constitutes, with BamD, the core component of the assembly machinery.

230089:VY86 RS09035
gene id: 230089:VY86_RS09035
uniprot id: A0A0F7LN63
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

230089:VY86 RS03095
gene id: 230089:VY86_RS03095
uniprot id: A0A0F7LK72
names: Similarity
messages: Belongs to the nucleoside-specific channel-forming outer membrane porin (Tsx) (TC 1.B.10) family.

230089:VY86 RS13520
gene id: 230089:VY86_RS13520
uniprot id: A0A0F7LLW8
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

230089:VY86 RS02940
gene id: 230089:VY86_RS02940
uniprot id: A0A0F7LIF4
names: Subcellular Location Annotation
messages: Membrane

230089:VY86 RS15225
gene id: 230089:VY86_RS15225
uniprot id: A0A0F7LMK5
names: Similarity
names: Subunit
messages: Belongs to the MoaE family.
messages: Heterotetramer of 2 MoaD subunits and 2 MoaE subunits. Also stable as homodimer. The enzyme changes between these two forms during catalysis.

230089:VY86 RS06360
gene id: 230089:VY86_RS06360
uniprot id: A0A0F7LME2
names: Similarity
messages: Belongs to the VgrG protein family.

230089:VY86 RS06940
gene id: 230089:VY86_RS06940
uniprot id: A0A0F7LM60
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

230089:VY86 RS21410
gene id: 230089:VY86_RS21410
uniprot id: A0A0F7LSA2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Flagellum-specific muramidase which hydrolyzes the peptidoglycan layer to assemble the rod structure in the periplasmic space.
messages: In the C-terminal section; belongs to the glycosyl hydrolase 73 family.
messages: In the N-terminal section; belongs to the FlgJ family.
messages: Periplasm

230089:VY86 RS10940
gene id: 230089:VY86_RS10940
uniprot id: A0A0F7LKU2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatB family.
messages: Cell membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

230089:VY86 RS14910
gene id: 230089:VY86_RS14910
uniprot id: A0A0F7LRF8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

230089:VY86 RS20555
gene id: 230089:VY86_RS20555
uniprot id: A0A0F7LQ72
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. GhrA subfamily.
messages: Catalyzes the NADPH-dependent reduction of glyoxylate and hydroxypyruvate into glycolate and glycerate, respectively.
messages: Cytoplasm

230089:VY86 RS14490
gene id: 230089:VY86_RS14490
uniprot id: A0A0F7LP27
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

230089:VY86 RS20335
gene id: 230089:VY86_RS20335
uniprot id: A0A0F7LTW9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family. MdtI subfamily.
messages: Catalyzes the excretion of spermidine.
messages: Cell membrane
messages: Forms a complex with MdtJ.
messages: Membrane

230089:VY86 RS02770
gene id: 230089:VY86_RS02770
uniprot id: A0A0F7LKL0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

230089:VY86 RS18225
gene id: 230089:VY86_RS18225
uniprot id: A0A0F7LP23
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArnE family.
messages: Cell inner membrane
messages: Heterodimer of ArnE and ArnF.
messages: Membrane
messages: Translocates 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol (alpha-L-Ara4N-phosphoundecaprenol) from the cytoplasmic to the periplasmic side of the inner membrane.

230089:VY86 RS01310
gene id: 230089:VY86_RS01310
uniprot id: A0A0F7LK56
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

230089:VY86 RS22090
gene id: 230089:VY86_RS22090
uniprot id: A0A0F7LUV5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MatP family.
messages: Cytoplasm
messages: Homodimer.
messages: Required for spatial organization of the terminus region of the chromosome (Ter macrodomain) during the cell cycle. Prevents early segregation of duplicated Ter macrodomains during cell division. Binds specifically to matS, which is a 13 bp signature motif repeated within the Ter macrodomain.

230089:VY86 RS19490
gene id: 230089:VY86_RS19490
uniprot id: A0A0F7LPP4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0719 family.
messages: Membrane

230089:VY86 RS13515
gene id: 230089:VY86_RS13515
uniprot id: A0A0F7LQ92
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

230089:VY86 RS04745
gene id: 230089:VY86_RS04745
uniprot id: A0A0F7LLI0
names: Function
names: Similarity
messages: Belongs to the peptidase M16 family.
messages: Endopeptidase that degrades small peptides of less than 7 kDa, such as glucagon and insulin.

230089:VY86 RS15635
gene id: 230089:VY86_RS15635
uniprot id: A0A0F7LS30
names: Similarity
messages: Belongs to the ClpA/ClpB family.

230089:VY86 RS14810
gene id: 230089:VY86_RS14810
uniprot id: A0A0F7LRN8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

230089:VY86 RS18720
gene id: 230089:VY86_RS18720
uniprot id: A0A0F7LPE1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NhaB Na(+)/H(+) (TC 2.A.34) antiporter family.
messages: Cell membrane
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

230089:VY86 RS04350
gene id: 230089:VY86_RS04350
uniprot id: A0A0F7LKW7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccA family.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

230089:VY86 RS06560
gene id: 230089:VY86_RS06560
uniprot id: A0A0F7LK69
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the polysaccharide transport (PST) (TC 2.A.66.2) family.
messages: Cell inner membrane
messages: Mediates the transbilayer movement of Und-PP-GlcNAc-ManNAcA-Fuc4NAc (lipid III) from the inner to the outer leaflet of the cytoplasmic membrane during the assembly of enterobacterial common antigen (ECA).
messages: Membrane
messages: Probably part of a complex composed of WzxE, WzyE and WzzE.

230089:VY86 RS13410
gene id: 230089:VY86_RS13410
uniprot id: A0A0F7LQI8
names: Similarity
messages: Belongs to the pirin family.

230089:VY86 RS14980
gene id: 230089:VY86_RS14980
uniprot id: A0A0F7LMF7
names: Similarity
messages: Belongs to the Nudix hydrolase family.

230089:VY86 RS10255
gene id: 230089:VY86_RS10255
uniprot id: A0A0F7LKF5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LDH/MDH superfamily. MDH type 1 family.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.
messages: Homodimer.

230089:VY86 RS00810
gene id: 230089:VY86_RS00810
uniprot id: A0A0F7LHI4
names: Similarity
messages: Belongs to the adrenodoxin/putidaredoxin family.

230089:VY86 RS17125
gene id: 230089:VY86_RS17125
uniprot id: A0A0F7LS84
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

230089:VY86 RS00390
gene id: 230089:VY86_RS00390
uniprot id: A0A0F7LHB5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccD/PCCB family.
messages: Binds 1 zinc ion per subunit.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

230089:VY86 RS12795
gene id: 230089:VY86_RS12795
uniprot id: A0A0F7LQ03
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbD subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps.

230089:VY86 RS15865
gene id: 230089:VY86_RS15865
uniprot id: A0A0F7LPV6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MukE family.
messages: Interacts, and probably forms a ternary complex, with MukF and MukB. The complex formation is stimulated by calcium or magnesium.
messages: Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF.
messages: nucleoid

230089:VY86 RS21785
gene id: 230089:VY86_RS21785
uniprot id: A0A0F7LUK1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CheZ family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P).

230089:VY86 RS17475
gene id: 230089:VY86_RS17475
uniprot id: A0A0F7LSG3
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.

230089:VY86 RS20780
gene id: 230089:VY86_RS20780
uniprot id: A0A0F7LUB6
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aquaporins contain two tandem repeats each containing three membrane-spanning domains and a pore-forming loop with the signature motif Asn-Pro-Ala (NPA).
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Cell membrane
messages: Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

230089:VY86 RS15355
gene id: 230089:VY86_RS15355
uniprot id: A0A0F7LMN1
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

230089:VY86 RS06240
gene id: 230089:VY86_RS06240
uniprot id: A0A0F7LR42
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. RlmB subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates the ribose of guanosine 2251 in 23S rRNA.

230089:VY86 RS08090
gene id: 230089:VY86_RS08090
uniprot id: A0A0F7LMQ8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

230089:VY86 RS04855
gene id: 230089:VY86_RS04855
uniprot id: A0A0F7LLR7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptD family.
messages: Cell outer membrane
messages: Component of the lipopolysaccharide transport and assembly complex. Interacts with LptE and LptA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane.

230089:VY86 RS06285
gene id: 230089:VY86_RS06285
uniprot id: A0A0F7LLS4
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

230089:VY86 RS19620
gene id: 230089:VY86_RS19620
uniprot id: A0A0F7LTL0
names: Subcellular Location Annotation
messages: Membrane

230089:VY86 RS17760
gene id: 230089:VY86_RS17760
uniprot id: A0A0F7LSL1
names: Similarity
messages: Belongs to the myoviridae tail sheath protein family.

230089:VY86 RS12275
gene id: 230089:VY86_RS12275
uniprot id: A0A0F7LQ83
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transglycosylase Slt family.
messages: Cell outer membrane
messages: Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and/or cell division.

230089:VY86 RS00705
gene id: 230089:VY86_RS00705
uniprot id: A0A0F7LHH0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the aerobic coproporphyrinogen-III oxidase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX.

230089:VY86 RS01285
gene id: 230089:VY86_RS01285
uniprot id: A0A0F7LK53
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm

230089:VY86 RS14865
gene id: 230089:VY86_RS14865
uniprot id: A0A0F7LRP6
names: Subcellular Location Annotation
messages: Membrane

230089:VY86 RS22160
gene id: 230089:VY86_RS22160
uniprot id: A0A0F7LUW1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
messages: Cell membrane
messages: Monomer.

230089:VY86 RS01335
gene id: 230089:VY86_RS01335
uniprot id: A0A0F7LK70
names: Similarity
messages: Belongs to the UPF0250 family.

230089:VY86 RS03520
gene id: 230089:VY86_RS03520
uniprot id: A0A0F7LIR1
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.
messages: This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.

230089:VY86 RS16230
gene id: 230089:VY86_RS16230
uniprot id: A0A0F7LMU9
names: Function
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.

230089:VY86 RS07555
gene id: 230089:VY86_RS07555
uniprot id: A0A0F7LJE7
names: Similarity
messages: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.

230089:VY86 RS13720
gene id: 230089:VY86_RS13720
uniprot id: A0A0F7LQV8
names: Subunit
messages: Monomer.

230089:VY86 RS15150
gene id: 230089:VY86_RS15150
uniprot id: A0A0F7LPI3
names: Function
names: Similarity
messages: Belongs to the cycloisomerase 2 family.
messages: Catalyzes the hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.

230089:VY86 RS16945
gene id: 230089:VY86_RS16945
uniprot id: A0A0F7LSA0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Bcr/CmlA family.
messages: Cell inner membrane
messages: Membrane

230089:VY86 RS15515
gene id: 230089:VY86_RS15515
uniprot id: A0A0F7LMN8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.
messages: Homodimer.

230089:VY86 RS02945
gene id: 230089:VY86_RS02945
uniprot id: A0A0F7LKN4
names: Function
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.
messages: Catalyzes the phosphorylation of guanosine and inosine to GMP and IMP, respectively.

230089:VY86 RS02275
gene id: 230089:VY86_RS02275
uniprot id: A0A0F7LGR5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.
messages: Cell inner membrane
messages: Membrane

230089:VY86 RS10955
gene id: 230089:VY86_RS10955
uniprot id: A0A0F7LPK9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RfaH family.
messages: Enhances distal genes transcription elongation in a specialized subset of operons that encode extracytoplasmic components. RfaH is recruited into a multi-component RNA polymerase complex by the ops element, which is a short conserved DNA sequence located downstream of the main promoter of these operons. Once bound, RfaH suppresses pausing and inhibits Rho-dependent and intrinsic termination at a subset of sites. Termination signals are bypassed, which allows complete synthesis of long RNA chains.
messages: Interacts with both the nontemplate DNA and the RNA polymerase (RNAP).

230089:VY86 RS02720
gene id: 230089:VY86_RS02720
uniprot id: A0A0F7LKJ7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome c oxidase bacterial subunit 4 family.
messages: Cytochrome bo(3) ubiquinol terminal oxidase is the component of the aerobic respiratory chain of E.coli that predominates when cells are grown at high aeration. Has proton pump activity across the membrane in addition to electron transfer, pumping 2 protons/electron.
messages: Heterooctamer of two A chains, two B chains, two C chains and two D chains.
messages: Membrane

230089:VY86 RS12950
gene id: 230089:VY86_RS12950
uniprot id: A0A0F7LQE1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
messages: Cell inner membrane
messages: Forms a membrane-associated complex with FtsE.
messages: Membrane
messages: Part of the ABC transporter FtsEX involved in cellular division.

230089:VY86 RS01930
gene id: 230089:VY86_RS01930
uniprot id: A0A0F7LM12
names: Similarity
messages: Belongs to the transposase 11 family.

230089:VY86 RS01905
gene id: 230089:VY86_RS01905
uniprot id: A0A0F7LHX4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

230089:VY86 RS14460
gene id: 230089:VY86_RS14460
uniprot id: A0A0F7LRE3
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

230089:VY86 RS00880
gene id: 230089:VY86_RS00880
uniprot id: A0A0F7LG53
names: Caution
names: Cofactor
names: Domain
names: Function
names: Similarity
messages: Belongs to the globin family. Two-domain flavohemoproteins subfamily.
messages: Binds 1 FAD per subunit.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.
messages: Consists of two distinct domains; an N-terminal heme-containing oxygen-binding domain and a C-terminal reductase domain with binding sites for FAD and NAD(P)H.
messages: In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
messages: Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

230089:VY86 RS13280
gene id: 230089:VY86_RS13280
uniprot id: A0A0F7LT07
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MlaE permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the ABC transporter complex MlaFEDB, which is involved in a phospholipid transport pathway that maintains lipid asymmetry in the outer membrane by retrograde trafficking of phospholipids from the outer membrane to the inner membrane. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (MlaF), two transmembrane proteins (MlaE), two cytoplasmic solute-binding proteins (MlaB) and six periplasmic solute-binding proteins (MlaD).

230089:VY86 RS01340
gene id: 230089:VY86_RS01340
uniprot id: A0A0F7LJD1
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LipB family.
messages: Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
messages: Cytoplasm
messages: In the reaction, the free carboxyl group of octanoic acid is attached via an amide linkage to the epsilon-amino group of a specific lysine residue of lipoyl domains of lipoate-dependent enzymes.

230089:VY86 RS16420
gene id: 230089:VY86_RS16420
uniprot id: A0A0F7LQ69
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

230089:VY86 RS05240
gene id: 230089:VY86_RS05240
uniprot id: A0A0F7LI94
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
messages: Cytoplasm
messages: Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.

230089:VY86 RS18955
gene id: 230089:VY86_RS18955
uniprot id: A0A0F7LTK5
names: Similarity
messages: In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.
messages: In the N-terminal section; belongs to the aldehyde dehydrogenase family.

230089:VY86 RS13225
gene id: 230089:VY86_RS13225
uniprot id: A0A0F7LQF4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RapZ-like family. RapZ subfamily.
messages: Homotrimer.
messages: Modulates the synthesis of GlmS, by affecting the processing and stability of the regulatory small RNA GlmZ. When glucosamine-6-phosphate (GlcN6P) concentrations are high in the cell, RapZ binds GlmZ and targets it to cleavage by RNase E. Consequently, GlmZ is inactivated and unable to activate GlmS synthesis. Under low GlcN6P concentrations, RapZ is sequestered and inactivated by an other regulatory small RNA, GlmY, preventing GlmZ degradation and leading to synthesis of GlmS.

230089:VY86 RS20785
gene id: 230089:VY86_RS20785
uniprot id: A0A0F7LU25
names: Similarity
messages: Belongs to the universal stress protein A family.

230089:VY86 RS10535
gene id: 230089:VY86_RS10535
uniprot id: A0A0F7LPD6
names: Function
names: Similarity
messages: Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.
messages: Belongs to the organic radical-activating enzymes family.

230089:VY86 RS00280
gene id: 230089:VY86_RS00280
uniprot id: A0A0F7LIZ4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FGGY kinase family.
messages: Catalyzes the phosphorylation of autoinducer-2 (AI-2) to phospho-AI-2, which subsequently inactivates the transcriptional regulator LsrR and leads to the transcription of the lsr operon. Phosphorylates the ring-open form of (S)-4,5-dihydroxypentane-2,3-dione (DPD), which is the precursor to all AI-2 signaling molecules, at the C5 position.
messages: Cytoplasm

230089:VY86 RS18610
gene id: 230089:VY86_RS18610
uniprot id: A0A0F7LT72
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

230089:VY86 RS15815
gene id: 230089:VY86_RS15815
uniprot id: A0A0F7LT18
names: Similarity
messages: Belongs to the iron/ascorbate-dependent oxidoreductase family.

230089:VY86 RS20695
gene id: 230089:VY86_RS20695
uniprot id: A0A0F7LUA6
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

230089:VY86 RS02850
gene id: 230089:VY86_RS02850
uniprot id: A0A0F7LKR6
names: Similarity
messages: Belongs to the Hha/YmoA/Cnu family.

230089:VY86 RS04430
gene id: 230089:VY86_RS04430
uniprot id: A0A0F7LLN1
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

230089:VY86 RS00885
gene id: 230089:VY86_RS00885
uniprot id: A0A0F7LHJ8
names: Subcellular Location Annotation
messages: Membrane
messages: Secreted
messages: host cytosol

230089:VY86 RS15405
gene id: 230089:VY86_RS15405
uniprot id: A0A0F7LRD6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: Binds 1 zinc ion.
messages: Homodimer.
messages: This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.

230089:VY86 RS15105
gene id: 230089:VY86_RS15105
uniprot id: A0A0F7LV82
names: Function
names: Similarity
messages: Belongs to the transposase 11 family.
messages: Involved in the transposition of the insertion sequence IS5.

230089:VY86 RS18920
gene id: 230089:VY86_RS18920
uniprot id: A0A0F7LR92
names: Similarity
messages: Belongs to the UPF0225 family.

230089:VY86 RS00730
gene id: 230089:VY86_RS00730
uniprot id: A0A0F7LHH3
names: Similarity
messages: Belongs to the YfgM family.

230089:VY86 RS07530
gene id: 230089:VY86_RS07530
uniprot id: A0A0F7LJD4
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

230089:VY86 RS09205
gene id: 230089:VY86_RS09205
uniprot id: A0A0F7LNV6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate:Na(+) symporter (ESS) (TC 2.A.27) family.
messages: Catalyzes the sodium-dependent transport of glutamate.
messages: Cell inner membrane

230089:VY86 RS03980
gene id: 230089:VY86_RS03980
uniprot id: A0A0F7LJ00
names: Similarity
messages: Belongs to the HipA Ser/Thr kinase family.

230089:VY86 RS21240
gene id: 230089:VY86_RS21240
uniprot id: A0A0F7LQL3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliL family.
messages: Cell inner membrane
messages: Controls the rotational direction of flagella during chemotaxis.
messages: Membrane

230089:VY86 RS16930
gene id: 230089:VY86_RS16930
uniprot id: A0A0F7LS50
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

230089:VY86 RS19300
gene id: 230089:VY86_RS19300
uniprot id: A0A0F7LRD4
names: Similarity
messages: Belongs to the myoviridae tail sheath protein family.

230089:VY86 RS05915
gene id: 230089:VY86_RS05915
uniprot id: A0A0F7LLK6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

230089:VY86 RS04925
gene id: 230089:VY86_RS04925
uniprot id: A0A0F7LLJ6
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

230089:VY86 RS08575
gene id: 230089:VY86_RS08575
uniprot id: A0A0F7LNF9
names: Similarity
messages: Belongs to the transposase 11 family.

230089:VY86 RS05505
gene id: 230089:VY86_RS05505
uniprot id: A0A0F7LLV8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the pseudouridine-5'-phosphate glycosidase family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the reversible cleavage of pseudouridine 5'-phosphate (PsiMP) to ribose 5-phosphate and uracil. Functions biologically in the cleavage direction, as part of a pseudouridine degradation pathway.
messages: Homotrimer.

230089:VY86 RS04185
gene id: 230089:VY86_RS04185
uniprot id: A0A0F7LKU9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Alpha(8)-beta(8). The alpha component is a flavoprotein, the beta component is a hemoprotein.
messages: Belongs to the NADPH-dependent sulphite reductase flavoprotein subunit CysJ family.
messages: Binds 1 FAD per subunit.
messages: Binds 1 FMN per subunit.
messages: Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH -> FAD -> FMN to the hemoprotein component.
messages: In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
messages: In the N-terminal section; belongs to the flavodoxin family.

230089:VY86 RS20620
gene id: 230089:VY86_RS20620
uniprot id: A0A0F7LU02
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KdsA family.
messages: Cytoplasm

230089:VY86 RS05615
gene id: 230089:VY86_RS05615
uniprot id: A0A0F7LIE5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AceK family.
messages: Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation.
messages: Cytoplasm

230089:VY86 RS05820
gene id: 230089:VY86_RS05820
uniprot id: A0A0F7LM77
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 1 family.
messages: Part of the ABC transporter complex MalEFGK involved in maltose/maltodextrin import. Binds maltose and higher maltodextrins.
messages: Periplasm

230089:VY86 RS21745
gene id: 230089:VY86_RS21745
uniprot id: A0A0F7LUJ8
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.
messages: In the N-terminal section; belongs to the transposase 2 family.

230089:VY86 RS05270
gene id: 230089:VY86_RS05270
uniprot id: A0A0F7LJK9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.
messages: Homodimer.
messages: The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis.

230089:VY86 RS07885
gene id: 230089:VY86_RS07885
uniprot id: A0A0F7LN75
names: Function
names: Subunit
messages: Adenylyltransferase that mediates the addition of adenosine 5'-monophosphate (AMP) to specific residues of target proteins.
messages: Homodimer.

230089:VY86 RS21915
gene id: 230089:VY86_RS21915
uniprot id: A0A0F7LUV3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.
messages: Membrane

230089:VY86 RS04255
gene id: 230089:VY86_RS04255
uniprot id: A0A0F7LLB1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RcsF family.
messages: Cell outer membrane
messages: Essential component of the Rcs signaling system, which controls transcription of numerous genes. Plays a role in signal transduction from the cell surface to the histidine kinase RcsC. May detect outer membrane defects.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

230089:VY86 RS14535
gene id: 230089:VY86_RS14535
uniprot id: A0A0F7LM93
names: Function
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

230089:VY86 RS20980
gene id: 230089:VY86_RS20980
uniprot id: A0A0F7LUD5
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The enzyme II FruAB PTS system is involved in fructose transport.

230089:VY86 RS16745
gene id: 230089:VY86_RS16745
uniprot id: A0A0F7LS07
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

230089:VY86 RS00375
gene id: 230089:VY86_RS00375
uniprot id: A0A0F7LJR1
names: Subcellular Location Annotation
messages: Membrane

230089:VY86 RS15615
gene id: 230089:VY86_RS15615
uniprot id: A0A0F7LRG5
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

230089:VY86 RS04250
gene id: 230089:VY86_RS04250
uniprot id: A0A0F7LJ52
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nlpA lipoprotein family.
messages: Membrane

230089:VY86 RS18335
gene id: 230089:VY86_RS18335
uniprot id: A0A0F7LTC7
names: Function
names: Similarity
messages: Belongs to the class-I DAHP synthase family.
messages: Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP).

230089:VY86 RS03730
gene id: 230089:VY86_RS03730
uniprot id: A0A0F7LL12
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

230089:VY86 RS02080
gene id: 230089:VY86_RS02080
uniprot id: A0A0F7LKB1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily.
messages: Catalyzes the oxidation of L-aspartate to iminoaspartate.
messages: Cytoplasm

230089:VY86 RS15780
gene id: 230089:VY86_RS15780
uniprot id: A0A0F7LPV0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Monomer.

230089:VY86 RS19330
gene id: 230089:VY86_RS19330
uniprot id: A0A0F7LPM7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

230089:VY86 RS02755
gene id: 230089:VY86_RS02755
uniprot id: A0A0F7LK16
names: Similarity
messages: Belongs to the BolA/IbaG family.

230089:VY86 RS02810
gene id: 230089:VY86_RS02810
uniprot id: A0A0F7LH15
names: Function
names: Similarity
messages: A cysteine desulfhydrase that generates hydrogen sulfide, H(2)S. The H(2)S produced by this enzyme may modulate central metabolism.
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family. Cds1 subfamily.

230089:VY86 RS16100
gene id: 230089:VY86_RS16100
uniprot id: A0A0F7LQ02
names: Similarity
messages: Belongs to the Rpn/YhgA-like nuclease family.

230089:VY86 RS11205
gene id: 230089:VY86_RS11205
uniprot id: A0A0F7LPN9
names: Subcellular Location Annotation
messages: Membrane

230089:VY86 RS15230
gene id: 230089:VY86_RS15230
uniprot id: A0A0F7LPJ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

230089:VY86 RS14570
gene id: 230089:VY86_RS14570
uniprot id: A0A0F7LP46
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Cell inner membrane
messages: Homoheptamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mechanosensitive channel that participates in the regulation of osmotic pressure changes within the cell, opening in response to stretch forces in the membrane lipid bilayer, without the need for other proteins. Contributes to normal resistance to hypoosmotic shock. Forms an ion channel of 1.0 nanosiemens conductance with a slight preference for anions.
messages: Membrane

230089:VY86 RS21805
gene id: 230089:VY86_RS21805
uniprot id: A0A0F7LUU2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Cell inner membrane
messages: Membrane

230089:VY86 RS05325
gene id: 230089:VY86_RS05325
uniprot id: A0A0F7LIA9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.
messages: Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.
messages: Cytoplasm
messages: Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).
messages: The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.
messages: The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1.

230089:VY86 RS20445
gene id: 230089:VY86_RS20445
uniprot id: A0A0F7LRQ3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. CmoB family.
messages: Catalyzes carboxymethyl transfer from carboxy-S-adenosyl-L-methionine (Cx-SAM) to 5-hydroxyuridine (ho5U) to form 5-carboxymethoxyuridine (cmo5U) at position 34 in tRNAs.
messages: Homotetramer.

230089:VY86 RS11485
gene id: 230089:VY86_RS11485
uniprot id: A0A0F7LMR4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KdpA family.
messages: Cell membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds the extracellular potassium ions and delivers the ions to the membrane domain of KdpB through an intramembrane tunnel.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

230089:VY86 RS19815
gene id: 230089:VY86_RS19815
uniprot id: A0A0F7LTM1
names: Similarity
messages: Belongs to the transposase 7 family.

230089:VY86 RS00850
gene id: 230089:VY86_RS00850
uniprot id: A0A0F7LJ79
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

230089:VY86 RS00380
gene id: 230089:VY86_RS00380
uniprot id: A0A0F7LJ01
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedD family.
messages: Cell inner membrane
messages: Non-essential cell division protein that could be required for efficient cell constriction.
messages: The SPOR domain binds septal peptidoglycans and is required to target DedD to the septal ring.

230089:VY86 RS05465
gene id: 230089:VY86_RS05465
uniprot id: A0A0F7LLF3
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

230089:VY86 RS09065
gene id: 230089:VY86_RS09065
uniprot id: A0A0F7LN64
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Monomer.

230089:VY86 RS01880
gene id: 230089:VY86_RS01880
uniprot id: A0A0F7LHX3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

230089:VY86 RS18830
gene id: 230089:VY86_RS18830
uniprot id: A0A0F7LT89
names: Similarity
messages: Belongs to the myoviridae tail sheath protein family.

230089:VY86 RS19165
gene id: 230089:VY86_RS19165
uniprot id: A0A0F7LRC0
names: Similarity
messages: Belongs to the SUI1 family.

230089:VY86 RS02760
gene id: 230089:VY86_RS02760
uniprot id: A0A0F7LH08
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

230089:VY86 RS06435
gene id: 230089:VY86_RS06435
uniprot id: A0A0F7LIT3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EamA transporter family.
messages: Membrane

230089:VY86 RS06595
gene id: 230089:VY86_RS06595
uniprot id: A0A0F7LML7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the WzzB/Cld/Rol family.
messages: Cell inner membrane
messages: Membrane
messages: Modulates the polysaccharide chain length of enterobacterial common antigen (ECA).
messages: Probably part of a complex composed of WzxE, WzyE and WzzE.

230089:VY86 RS06890
gene id: 230089:VY86_RS06890
uniprot id: A0A0F7LM28
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

230089:VY86 RS07035
gene id: 230089:VY86_RS07035
uniprot id: A0A0F7LMV7
names: Function
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.
messages: Provides the (R)-glutamate required for cell wall biosynthesis.

230089:VY86 RS02010
gene id: 230089:VY86_RS02010
uniprot id: A0A0F7LM12
names: Similarity
messages: Belongs to the transposase 11 family.

230089:VY86 RS06465
gene id: 230089:VY86_RS06465
uniprot id: A0A0F7LK65
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD, in which XerC interacts with XerD via its C-terminal region, XerD interacts with XerC via its C-terminal region and so on.
messages: FtsK may regulate the catalytic switch between XerC and XerD in the heterotetrameric complex during the two steps of the recombination process.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. Binds cooperatively to specific DNA consensus sequences that are separated from XerD binding sites by a short central region, forming the heterotetrameric XerC-XerD complex that recombines DNA substrates. The complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids. In the complex XerC specifically exchanges the top DNA strands.

230089:VY86 RS05340
gene id: 230089:VY86_RS05340
uniprot id: A0A0F7LLZ1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the YjjX NTPase family.
messages: Binds 1 divalent metal cation per subunit; can use either Mg(2+) or Mn(2+).
messages: Homodimer.
messages: Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA/RNA precursor pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

230089:VY86 RS05770
gene id: 230089:VY86_RS05770
uniprot id: A0A0F7LLJ9
names: Activity Regulation
names: Function
names: Similarity
names: Subunit
messages: Activated by ATP and maltotriose, which are both required for DNA binding.
messages: Belongs to the MalT family.
messages: Monomer in solution. Oligomerizes to an active state in the presence of the positive effectors ATP and maltotriose.
messages: Positively regulates the transcription of the maltose regulon whose gene products are responsible for uptake and catabolism of malto-oligosaccharides. Specifically binds to the promoter region of its target genes, recognizing a short DNA motif called the MalT box.

230089:VY86 RS14920
gene id: 230089:VY86_RS14920
uniprot id: A0A0F7LR40
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

230089:VY86 RS01410
gene id: 230089:VY86_RS01410
uniprot id: A0A0F7LK76
names: Subcellular Location Annotation
messages: Membrane

230089:VY86 RS06900
gene id: 230089:VY86_RS06900
uniprot id: A0A0F7LKB7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

230089:VY86 RS06015
gene id: 230089:VY86_RS06015
uniprot id: A0A0F7LLL6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NAD(P)H dehydrogenase (quinone) family. KefG subfamily.
messages: Cell inner membrane
messages: Interacts with KefB.
messages: Regulatory subunit of a potassium efflux system that confers protection against electrophiles. Required for full activity of KefB.

230089:VY86 RS09030
gene id: 230089:VY86_RS09030
uniprot id: A0A0F7LNL6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

230089:VY86 RS10160
gene id: 230089:VY86_RS10160
uniprot id: A0A0F7LM32
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

230089:VY86 RS09055
gene id: 230089:VY86_RS09055
uniprot id: A0A0F7LNQ0
names: Function
names: Similarity
names: Subunit
messages: A GTPase-activating protein (GAP) that modifies Der/EngA GTPase function. May play a role in ribosome biogenesis.
messages: Belongs to the YihI family.
messages: Interacts with Der.

230089:VY86 RS22055
gene id: 230089:VY86_RS22055
uniprot id: A0A0F7LQT8
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

230089:VY86 RS03650
gene id: 230089:VY86_RS03650
uniprot id: A0A0F7LKZ3
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic AdoMetDC family. Type 2 subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine.
messages: Heterooctamer of four alpha and four beta chains arranged as a tetramer of alpha/beta heterodimers.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl group blocking the N-terminus of the alpha chain.

230089:VY86 RS12015
gene id: 230089:VY86_RS12015
uniprot id: A0A0F7LPE3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

230089:VY86 RS08225
gene id: 230089:VY86_RS08225
uniprot id: A0A0F7LL38
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Cell inner membrane
messages: Membrane
messages: Transports acetate.

230089:VY86 RS18665
gene id: 230089:VY86_RS18665
uniprot id: A0A0F7LT77
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Cell inner membrane
messages: Membrane
messages: Zinc transporter. Acts as a Zn(2+):proton symporter, which likely mediates zinc ion uptake.

230089:VY86 RS14165
gene id: 230089:VY86_RS14165
uniprot id: A0A0F7LQZ7
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.
messages: In the N-terminal section; belongs to the transposase 2 family.

230089:VY86 RS10550
gene id: 230089:VY86_RS10550
uniprot id: A0A0F7LKM8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PyrI family.
messages: Binds 1 zinc ion per subunit.
messages: Contains catalytic and regulatory chains.
messages: Involved in allosteric regulation of aspartate carbamoyltransferase.

230089:VY86 RS19880
gene id: 230089:VY86_RS19880
uniprot id: A0A0F7LU04
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

230089:VY86 RS18020
gene id: 230089:VY86_RS18020
uniprot id: A0A0F7LSS7
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Homodimer.
messages: The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The enzyme II ManXYZ PTS system is involved in mannose transport.

230089:VY86 RS15775
gene id: 230089:VY86_RS15775
uniprot id: A0A0F7LMQ1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

230089:VY86 RS12270
gene id: 230089:VY86_RS12270
uniprot id: A0A0F7LPZ4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Fe(2+)-trafficking protein family.
messages: Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes.
messages: Monomer.

230089:VY86 RS00570
gene id: 230089:VY86_RS00570
uniprot id: A0A0F7LJV2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial glucokinase family.
messages: Cytoplasm

230089:VY86 RS01400
gene id: 230089:VY86_RS01400
uniprot id: A0A0F7LHR5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

230089:VY86 RS16750
gene id: 230089:VY86_RS16750
uniprot id: A0A0F7LN45
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CbiM family.
messages: Cell membrane
messages: Forms an energy-coupling factor (ECF) transporter complex composed of an ATP-binding protein (A component, CbiO), a transmembrane protein (T component, CbiQ) and 2 possible substrate-capture proteins (S components, CbiM and CbiN) of unknown stoichimetry.
messages: Membrane
messages: Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import.

230089:VY86 RS04770
gene id: 230089:VY86_RS04770
uniprot id: A0A0F7LLI5
names: Subcellular Location Annotation
messages: Membrane

230089:VY86 RS06545
gene id: 230089:VY86_RS06545
uniprot id: A0A0F7LML0
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 26 family.
messages: Catalyzes the synthesis of Und-PP-GlcNAc-ManNAcA (Lipid II), the second lipid-linked intermediate involved in enterobacterial common antigen (ECA) synthesis.

230089:VY86 RS08095
gene id: 230089:VY86_RS08095
uniprot id: A0A0F7LJP2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family. T3SS ATPase subfamily.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has four main subunits: a(1), b(1), b'(1) and c(9-12).
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

230089:VY86 RS21810
gene id: 230089:VY86_RS21810
uniprot id: A0A0F7LUK5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Cell inner membrane
messages: Membrane

230089:VY86 RS20600
gene id: 230089:VY86_RS20600
uniprot id: A0A0F7LRS1
names: Function
names: Similarity
messages: Acyl transferase is part of the fatty acid reductase system required for aldehyde biosynthesis; it produces fatty acids for the luminescent reaction.
messages: Belongs to the LuxD family.

230089:VY86 RS17230
gene id: 230089:VY86_RS17230
uniprot id: A0A0F7LNC0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

230089:VY86 RS04450
gene id: 230089:VY86_RS04450
uniprot id: A0A0F7LLE0
names: Similarity
messages: Belongs to the UPF0325 family.

230089:VY86 RS20730
gene id: 230089:VY86_RS20730
uniprot id: A0A0F7LQ94
names: Subcellular Location Annotation
messages: Membrane

230089:VY86 RS04075
gene id: 230089:VY86_RS04075
uniprot id: A0A0F7LHP8
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

230089:VY86 RS18715
gene id: 230089:VY86_RS18715
uniprot id: A0A0F7LT82
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DsbB family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein.

230089:VY86 RS13745
gene id: 230089:VY86_RS13745
uniprot id: A0A0F7LQS8
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

230089:VY86 RS20430
gene id: 230089:VY86_RS20430
uniprot id: A0A0F7LU85
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp).
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

230089:VY86 RS16740
gene id: 230089:VY86_RS16740
uniprot id: A0A0F7LSI4
names: Function
names: Similarity
messages: Belongs to the CbiK family.
messages: Catalyzes the insertion of Co(2+) into sirohydrochlorin.

230089:VY86 RS06145
gene id: 230089:VY86_RS06145
uniprot id: A0A0F7LV74
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

230089:VY86 RS00295
gene id: 230089:VY86_RS00295
uniprot id: A0A0F7LHA0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DeoC/FbaB aldolase family.
messages: Cytoplasm
messages: Homodecamer.
messages: Involved in the degradation of phospho-AI-2, thereby terminating induction of the lsr operon and closing the AI-2 signaling cycle. Catalyzes the transfer of an acetyl moiety from 3-hydroxy-5-phosphonooxypentane-2,4-dione to CoA to form glycerone phosphate and acetyl-CoA.

230089:VY86 RS22000
gene id: 230089:VY86_RS22000
uniprot id: A0A0F7LPN2
names: Similarity
messages: Belongs to the transposase 11 family.

230089:VY86 RS15995
gene id: 230089:VY86_RS15995
uniprot id: A0A0F7LV89
names: Similarity
messages: Belongs to the myoviridae tail sheath protein family.

230089:VY86 RS06865
gene id: 230089:VY86_RS06865
uniprot id: A0A0F7LM25
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

230089:VY86 RS02475
gene id: 230089:VY86_RS02475
uniprot id: A0A0F7LJV1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

230089:VY86 RS18420
gene id: 230089:VY86_RS18420
uniprot id: A0A0F7LR32
names: Similarity
messages: Belongs to the glycosyl hydrolase 39 family.

230089:VY86 RS20610
gene id: 230089:VY86_RS20610
uniprot id: A0A0F7LU98
names: Similarity
messages: Belongs to the NodU/CmcH family.

230089:VY86 RS18345
gene id: 230089:VY86_RS18345
uniprot id: A0A0F7LP47
names: Function
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.
messages: Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate.

230089:VY86 RS13180
gene id: 230089:VY86_RS13180
uniprot id: A0A0F7LQM6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YhdE subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

230089:VY86 RS19160
gene id: 230089:VY86_RS19160
uniprot id: A0A0F7LPK7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the OMP decarboxylase family. Type 1 subfamily.
messages: Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
messages: Homodimer.

230089:VY86 RS20415
gene id: 230089:VY86_RS20415
uniprot id: A0A0F7LQ55
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvC family.
messages: Binds 2 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer which binds Holliday junction (HJ) DNA. The HJ becomes 2-fold symmetrical on binding to RuvC with unstacked arms; it has a different conformation from HJ DNA in complex with RuvA. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair. Endonuclease that resolves HJ intermediates. Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction. The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'. Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange. HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

230089:VY86 RS08120
gene id: 230089:VY86_RS08120
uniprot id: A0A0F7LJP6
names: Subcellular Location Annotation
messages: Membrane

230089:VY86 RS07040
gene id: 230089:VY86_RS07040
uniprot id: A0A0F7LM66
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family. BtuB (TC 1.B.14.3.1) subfamily.
messages: Cell outer membrane
messages: Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

230089:VY86 RS05175
gene id: 230089:VY86_RS05175
uniprot id: A0A0F7LI77
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

230089:VY86 RS22170
gene id: 230089:VY86_RS22170
uniprot id: A0A0F7LUP3
names: Function
names: PTM
names: Similarity
messages: Belongs to the NAPRTase family.
messages: Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP.
messages: Transiently phosphorylated on a His residue during the reaction cycle. Phosphorylation strongly increases the affinity for substrates and increases the rate of nicotinate D-ribonucleotide production. Dephosphorylation regenerates the low-affinity form of the enzyme, leading to product release.

230089:VY86 RS16215
gene id: 230089:VY86_RS16215
uniprot id: A0A0F7LS19
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 20 kDa subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Cell membrane
messages: NDH-1 is composed of 13 different subunits. Subunits NuoB, CD, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

230089:VY86 RS19345
gene id: 230089:VY86_RS19345
uniprot id: A0A0F7LTS9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrB/RnfD family.
messages: Cell inner membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

230089:VY86 RS10875
gene id: 230089:VY86_RS10875
uniprot id: A0A0F7LPJ8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

230089:VY86 RS03015
gene id: 230089:VY86_RS03015
uniprot id: A0A0F7LKU5
names: Similarity
messages: Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family.

230089:VY86 RS04695
gene id: 230089:VY86_RS04695
uniprot id: A0A0F7LL32
names: Subcellular Location Annotation
messages: Membrane

230089:VY86 RS15570
gene id: 230089:VY86_RS15570
uniprot id: A0A0F7LMP2
names: Similarity
names: Subunit
messages: Belongs to the glutaredoxin family.
messages: Monomer.

230089:VY86 RS13435
gene id: 230089:VY86_RS13435
uniprot id: A0A0F7LQJ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ElaB/YgaM/YqjD family.
messages: Cell inner membrane
messages: Membrane

230089:VY86 RS13775
gene id: 230089:VY86_RS13775
uniprot id: A0A0F7LNU5
names: Similarity
messages: Belongs to the glycosyl hydrolase 39 family.

230089:VY86 RS01275
gene id: 230089:VY86_RS01275
uniprot id: A0A0F7LHP7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

230089:VY86 RS20690
gene id: 230089:VY86_RS20690
uniprot id: A0A0F7LU53
names: Similarity
messages: Belongs to the VapB family.

230089:VY86 RS17480
gene id: 230089:VY86_RS17480
uniprot id: A0A0F7LSU1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

230089:VY86 RS19110
gene id: 230089:VY86_RS19110
uniprot id: A0A0F7LVK4
names: Similarity
messages: Belongs to the peptidase S49 family.

230089:VY86 RS12800
gene id: 230089:VY86_RS12800
uniprot id: A0A0F7LLL7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DcuA/DcuB transporter (TC 2.A.13.1) family.
messages: Cell inner membrane
messages: Membrane
messages: Responsible for the transport of C4-dicarboxylates.

230089:VY86 RS03770
gene id: 230089:VY86_RS03770
uniprot id: A0A0F7LHK6
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.

230089:VY86 RS04070
gene id: 230089:VY86_RS04070
uniprot id: A0A0F7LKT7
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

230089:VY86 RS12860
gene id: 230089:VY86_RS12860
uniprot id: A0A0F7LNK9
names: Cofactor
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Binds 1 [3Fe-4S] cluster.
messages: Binds 1 [4Fe-4S] cluster.

230089:VY86 RS14870
gene id: 230089:VY86_RS14870
uniprot id: A0A0F7LR31
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

230089:VY86 RS18785
gene id: 230089:VY86_RS18785
uniprot id: A0A0F7LTJ2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the type IA topoisomerase family.
messages: Binds two Mg(2+) per subunit.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

230089:VY86 RS02255
gene id: 230089:VY86_RS02255
uniprot id: A0A0F7LHZ4
names: Similarity
messages: Belongs to the LcrH/SycD chaperone family.

230089:VY86 RS09280
gene id: 230089:VY86_RS09280
uniprot id: A0A0F7LK57
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the periplasmic pilus chaperone family.
messages: Periplasm

230089:VY86 RS02920
gene id: 230089:VY86_RS02920
uniprot id: A0A0F7LKN2
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

230089:VY86 RS15590
gene id: 230089:VY86_RS15590
uniprot id: A0A0F7LRG2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

230089:VY86 RS19420
gene id: 230089:VY86_RS19420
uniprot id: A0A0F7LV82
names: Function
names: Similarity
messages: Belongs to the transposase 11 family.
messages: Involved in the transposition of the insertion sequence IS5.

230089:VY86 RS10895
gene id: 230089:VY86_RS10895
uniprot id: A0A0F7LMI0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase C15 family.
messages: Cytoplasm
messages: Homotetramer.
messages: Removes 5-oxoproline from various penultimate amino acid residues except L-proline.

230089:VY86 RS16765
gene id: 230089:VY86_RS16765
uniprot id: A0A0F7LSI6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Part of an ABC transporter complex. Responsible for energy coupling to the transport system.

230089:VY86 RS18975
gene id: 230089:VY86_RS18975
uniprot id: A0A0F7LTC1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

230089:VY86 RS06615
gene id: 230089:VY86_RS06615
uniprot id: A0A0F7LMH0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DEAD box helicase family. RhlB subfamily.
messages: Component of the RNA degradosome, which is a multiprotein complex involved in RNA processing and mRNA degradation.
messages: Cytoplasm
messages: DEAD-box RNA helicase involved in RNA degradation. Has RNA-dependent ATPase activity and unwinds double-stranded RNA.

230089:VY86 RS11965
gene id: 230089:VY86_RS11965
uniprot id: A0A0F7LMY9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

230089:VY86 RS00460
gene id: 230089:VY86_RS00460
uniprot id: A0A0F7LJS1
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

230089:VY86 RS09005
gene id: 230089:VY86_RS09005
uniprot id: A0A0F7LNL4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

230089:VY86 RS01365
gene id: 230089:VY86_RS01365
uniprot id: A0A0F7LK73
names: Function
names: Similarity
messages: Belongs to the glutaredoxin family.
messages: Electron transport system for the ribonucleotide reductase system NrdEF.

230089:VY86 RS21140
gene id: 230089:VY86_RS21140
uniprot id: A0A0F7LS52
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

230089:VY86 RS05920
gene id: 230089:VY86_RS05920
uniprot id: A0A0F7LIG5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

230089:VY86 RS10320
gene id: 230089:VY86_RS10320
uniprot id: A0A0F7LPC6
names: Function
names: Similarity
messages: Belongs to the DHPS family.
messages: Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives.

230089:VY86 RS18535
gene id: 230089:VY86_RS18535
uniprot id: A0A0F7LPA6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase T family.
messages: Binds two Mg(2+) per subunit. The active form of the enzyme binds two Mg(2+) ions in its active site. The first Mg(2+) forms only one salt bridge with the protein.
messages: Homodimer.
messages: Trims short 3' overhangs of a variety of RNA species, leaving a one or two nucleotide 3' overhang. Responsible for the end-turnover of tRNA: specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis.

230089:VY86 RS15170
gene id: 230089:VY86_RS15170
uniprot id: A0A0F7LR76
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily.
messages: Catalyzes the decarboxylative condensation of pimeloyl-[acyl-carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide.
messages: Homodimer.

230089:VY86 RS06775
gene id: 230089:VY86_RS06775
uniprot id: A0A0F7LMH7
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the shikimate dehydrogenase family.
messages: Homodimer.
messages: Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

230089:VY86 RS04735
gene id: 230089:VY86_RS04735
uniprot id: A0A0F7LI08
names: Function
names: Similarity
names: Subunit
messages: A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD.
messages: Belongs to the RecD family.
messages: Heterotrimer of RecB, RecC and RecD. All subunits contribute to DNA-binding.

230089:VY86 RS15220
gene id: 230089:VY86_RS15220
uniprot id: A0A0F7LR83
names: Similarity
messages: Belongs to the MoaD family.

230089:VY86 RS02880
gene id: 230089:VY86_RS02880
uniprot id: A0A0F7LK37
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BioY family.
messages: Cell membrane

230089:VY86 RS00510
gene id: 230089:VY86_RS00510
uniprot id: A0A0F7LJK0
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAL/histidase family.
messages: Contains an active site 4-methylidene-imidazol-5-one (MIO), which is formed autocatalytically by cyclization and dehydration of residues Ala-Ser-Gly.
messages: Cytoplasm

230089:VY86 RS14945
gene id: 230089:VY86_RS14945
uniprot id: A0A0F7LR45
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsQ/DivIB family. FtsQ subfamily.
messages: Cell inner membrane
messages: Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly.
messages: Part of a complex composed of FtsB, FtsL and FtsQ.

230089:VY86 RS03825
gene id: 230089:VY86_RS03825
uniprot id: A0A0F7LL97
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BtuF family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC.
messages: Periplasm
messages: The complex is composed of two ATP-binding proteins (BtuD), two transmembrane proteins (BtuC) and a solute-binding protein (BtuF).

230089:VY86 RS09540
gene id: 230089:VY86_RS09540
uniprot id: A0A0F7LP33
names: Similarity
messages: Belongs to the peptidase M16 family.

230089:VY86 RS16190
gene id: 230089:VY86_RS16190
uniprot id: A0A0F7LS17
names: Subcellular Location Annotation
messages: Membrane

230089:VY86 RS12855
gene id: 230089:VY86_RS12855
uniprot id: A0A0F7LLM2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FrdC family.
messages: Cell membrane
messages: Part of an enzyme complex containing four subunits: a flavoprotein (FrdA), an iron-sulfur protein (FrdB), and two hydrophobic anchor proteins (FrdC and FrdD).
messages: Two distinct, membrane-bound, FAD-containing enzymes are responsible for the catalysis of fumarate and succinate interconversion; fumarate reductase is used in anaerobic growth, and succinate dehydrogenase is used in aerobic growth. Anchors the catalytic components of the fumarate reductase complex to the cell inner membrane, binds quinones.

230089:VY86 RS18490
gene id: 230089:VY86_RS18490
uniprot id: A0A0F7LT54
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family. MdtK subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Multidrug efflux pump that functions probably as a Na(+)/drug antiporter.

230089:VY86 RS06275
gene id: 230089:VY86_RS06275
uniprot id: A0A0F7LMD3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Hfq family.
messages: Homohexamer.
messages: RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs.

230089:VY86 RS15200
gene id: 230089:VY86_RS15200
uniprot id: A0A0F7LMK2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

230089:VY86 RS18435
gene id: 230089:VY86_RS18435
uniprot id: A0A0F7LT49
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

230089:VY86 RS13250
gene id: 230089:VY86_RS13250
uniprot id: A0A0F7LQG6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptA family.
messages: Component of the lipopolysaccharide transport and assembly complex.
messages: Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm.
messages: Periplasm

230089:VY86 RS03655
gene id: 230089:VY86_RS03655
uniprot id: A0A0F7LL73
names: Function
names: Similarity
names: Subunit
messages: Belongs to the spermidine/spermine synthase family.
messages: Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
messages: Homodimer or homotetramer.

230089:VY86 RS21155
gene id: 230089:VY86_RS21155
uniprot id: A0A0F7LUL7
names: Subcellular Location Annotation
messages: Membrane

230089:VY86 RS06850
gene id: 230089:VY86_RS06850
uniprot id: A0A0F7LMJ3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

230089:VY86 RS19060
gene id: 230089:VY86_RS19060
uniprot id: A0A0F7LTC4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

230089:VY86 RS10290
gene id: 230089:VY86_RS10290
uniprot id: A0A0F7LP95
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

230089:VY86 RS15625
gene id: 230089:VY86_RS15625
uniprot id: A0A0F7LPT4
names: Subcellular Location Annotation
messages: Cytoplasm

230089:VY86 RS14900
gene id: 230089:VY86_RS14900
uniprot id: A0A0F7LME1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transpeptidase family. FtsI subfamily.
messages: Catalyzes cross-linking of the peptidoglycan cell wall at the division septum.
messages: Cell inner membrane

230089:VY86 RS20140
gene id: 230089:VY86_RS20140
uniprot id: A0A0F7LU37
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the urease beta subunit family.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

230089:VY86 RS05335
gene id: 230089:VY86_RS05335
uniprot id: A0A0F7LLT7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TrpR family.
messages: Cytoplasm
messages: Homodimer.
messages: This protein is an aporepressor. When complexed with L-tryptophan it binds the operator region of the trp operon (5'-ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region.

230089:VY86 RS10800
gene id: 230089:VY86_RS10800
uniprot id: A0A0F7LMF9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LamB/PxpA family.
messages: Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.
messages: Forms a complex composed of PxpA, PxpB and PxpC.

230089:VY86 RS01555
gene id: 230089:VY86_RS01555
uniprot id: A0A0F7LJF7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

230089:VY86 RS19445
gene id: 230089:VY86_RS19445
uniprot id: A0A0F7LT39
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.
messages: There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors.

230089:VY86 RS20605
gene id: 230089:VY86_RS20605
uniprot id: A0A0F7LU40
names: Function
names: Similarity
messages: Belongs to the LuxC family.
messages: LuxC is the fatty acid reductase enzyme responsible for synthesis of the aldehyde substrate for the luminescent reaction catalyzed by luciferase.

230089:VY86 RS17195
gene id: 230089:VY86_RS17195
uniprot id: A0A0F7LSQ2
names: Function
names: Similarity
messages: Belongs to the thiamine kinase family.
messages: Catalyzes the phosphorylation of thiamine to thiamine phosphate.

230089:VY86 RS16415
gene id: 230089:VY86_RS16415
uniprot id: A0A0F7LMX8
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.

230089:VY86 RS04530
gene id: 230089:VY86_RS04530
uniprot id: A0A0F7LL14
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family. QueF type 2 subfamily.
messages: Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
messages: Cytoplasm
messages: Homodimer.

230089:VY86 RS20115
gene id: 230089:VY86_RS20115
uniprot id: A0A0F7LU33
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UreD family.
messages: Cytoplasm
messages: Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
messages: UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

230089:VY86 RS14780
gene id: 230089:VY86_RS14780
uniprot id: A0A0F7LRB4
names: Function
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. SpeA subfamily.
messages: Catalyzes the biosynthesis of agmatine from arginine.

230089:VY86 RS05480
gene id: 230089:VY86_RS05480
uniprot id: A0A0F7LLV7
names: Function
messages: Colicins are polypeptide toxins produced by and active against E.coli and closely related bacteria.

230089:VY86 RS06550
gene id: 230089:VY86_RS06550
uniprot id: A0A0F7LLW6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the WzyE family.
messages: Cell inner membrane
messages: Probably involved in the polymerization of enterobacterial common antigen (ECA) trisaccharide repeat units.
messages: Probably part of a complex composed of WzxE, WzyE and WzzE.

230089:VY86 RS03755
gene id: 230089:VY86_RS03755
uniprot id: A0A0F7LL13
names: Similarity
messages: Belongs to the SfsA family.

230089:VY86 RS03460
gene id: 230089:VY86_RS03460
uniprot id: A0A0F7LIQ8
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.
messages: In the N-terminal section; belongs to the transposase 2 family.

230089:VY86 RS10885
gene id: 230089:VY86_RS10885
uniprot id: A0A0F7LVC5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 independent methionine synthase family.
messages: Binds 1 zinc ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine resulting in methionine formation.

230089:VY86 RS13195
gene id: 230089:VY86_RS13195
uniprot id: A0A0F7LNN8
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.

230089:VY86 RS09265
gene id: 230089:VY86_RS09265
uniprot id: A0A0F7LNW1
names: Function
names: Similarity
messages: Belongs to the helicase family. RecG subfamily.
messages: Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA).

230089:VY86 RS04165
gene id: 230089:VY86_RS04165
uniprot id: A0A0F7LHR3
names: Subcellular Location Annotation
messages: Membrane

230089:VY86 RS13750
gene id: 230089:VY86_RS13750
uniprot id: A0A0F7LV72
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the exbB/tolQ family.
messages: Cell inner membrane
messages: Involved in the TonB-dependent energy-dependent transport of various receptor-bound substrates. Protects ExbD from proteolytic degradation and functionally stabilizes TonB.
messages: Membrane
messages: The accessory proteins ExbB and ExbD seem to form a complex with TonB.

230089:VY86 RS15745
gene id: 230089:VY86_RS15745
uniprot id: A0A0F7LMQ0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycyl radical enzyme (GRE) family. PFL subfamily.
messages: Cytoplasm
messages: Homodimer.

230089:VY86 RS04380
gene id: 230089:VY86_RS04380
uniprot id: A0A0F7LHT3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
messages: Catalyzes the N-acylation of UDP-3-O-(hydroxytetradecanoyl)glucosamine using 3-hydroxytetradecanoyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
messages: Homotrimer.

230089:VY86 RS06705
gene id: 230089:VY86_RS06705
uniprot id: A0A0F7LM04
names: Function
names: Similarity
messages: Acts on leucine, isoleucine and valine.
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

230089:VY86 RS15690
gene id: 230089:VY86_RS15690
uniprot id: A0A0F7LRH0
names: Subcellular Location Annotation
messages: Membrane

230089:VY86 RS21250
gene id: 230089:VY86_RS21250
uniprot id: A0A0F7LUI7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliN/MopA/SpaO family.
messages: Cell membrane
messages: FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
messages: Membrane

230089:VY86 RS13150
gene id: 230089:VY86_RS13150
uniprot id: A0A0F7LQM2
names: Function
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

230089:VY86 RS11320
gene id: 230089:VY86_RS11320
uniprot id: A0A0F7LMN7
names: Subcellular Location Annotation
messages: Cell inner membrane

230089:VY86 RS22205
gene id: 230089:VY86_RS22205
uniprot id: A0A0F7LSN4
names: Similarity
messages: Belongs to the YkuD family.

230089:VY86 RS02860
gene id: 230089:VY86_RS02860
uniprot id: A0A0F7LH23
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

230089:VY86 RS08145
gene id: 230089:VY86_RS08145
uniprot id: A0A0F7LJP7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. AsnA subfamily.
messages: Cytoplasm

230089:VY86 RS17290
gene id: 230089:VY86_RS17290
uniprot id: A0A0F7LSD4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
messages: Catalyzes two reactions in de novo purine nucleotide biosynthesis. Catalyzes the breakdown of 5-aminoimidazole- (N-succinylocarboxamide) ribotide (SAICAR or 2-[5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamido]succinate) to 5-aminoimidazole-4-carboxamide ribotide (AICAR or 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide) and fumarate, and of adenylosuccinate (ADS or N(6)-(1,2-dicarboxyethyl)-AMP) to adenosine monophosphate (AMP) and fumarate.
messages: Homotetramer. Residues from neighboring subunits contribute catalytic and substrate-binding residues to each active site.

230089:VY86 RS00725
gene id: 230089:VY86_RS00725
uniprot id: A0A0F7LG40
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamB family.
messages: Cell outer membrane
messages: Part of the Bam complex, which is composed of the outer membrane protein BamA, and four lipoproteins BamB, BamC, BamD and BamE.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

230089:VY86 RS20035
gene id: 230089:VY86_RS20035
uniprot id: A0A0F7LU20
names: Similarity
messages: Belongs to the bacterial ring-hydroxylating dioxygenase beta subunit family.

230089:VY86 RS20345
gene id: 230089:VY86_RS20345
uniprot id: A0A0F7LRN9
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

230089:VY86 RS11555
gene id: 230089:VY86_RS11555
uniprot id: A0A0F7LPN2
names: Similarity
messages: Belongs to the transposase 11 family.

230089:VY86 RS07190
gene id: 230089:VY86_RS07190
uniprot id: A0A0F7LMY7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

230089:VY86 RS02330
gene id: 230089:VY86_RS02330
uniprot id: A0A0F7LGS5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliQ/MopD/SpaQ family.
messages: Cell membrane
messages: Membrane

230089:VY86 RS13680
gene id: 230089:VY86_RS13680
uniprot id: A0A0F7LLZ4
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

230089:VY86 RS08125
gene id: 230089:VY86_RS08125
uniprot id: A0A0F7LL35
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the N7 position of guanine in position 527 of 16S rRNA.

230089:VY86 RS03050
gene id: 230089:VY86_RS03050
uniprot id: A0A0F7LH52
names: Subcellular Location Annotation
messages: Membrane

230089:VY86 RS15165
gene id: 230089:VY86_RS15165
uniprot id: A0A0F7LRU1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. Biotin synthase family.
messages: Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
messages: Homodimer.

230089:VY86 RS10935
gene id: 230089:VY86_RS10935
uniprot id: A0A0F7LNZ9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

230089:VY86 RS08885
gene id: 230089:VY86_RS08885
uniprot id: A0A0F7LJY5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GlpE family.
messages: Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide.
messages: Cytoplasm

230089:VY86 RS13715
gene id: 230089:VY86_RS13715
uniprot id: A0A0F7LQS5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FtsP family.
messages: Cell division protein that is required for growth during stress conditions. May be involved in protecting or stabilizing the divisomal assembly under conditions of stress.
messages: Periplasm

230089:VY86 RS04575
gene id: 230089:VY86_RS04575
uniprot id: A0A0F7LLG3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0382 family.
messages: Membrane

230089:VY86 RS10755
gene id: 230089:VY86_RS10755
uniprot id: A0A0F7LPI5
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

230089:VY86 RS10360
gene id: 230089:VY86_RS10360
uniprot id: A0A0F7LPD1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

230089:VY86 RS08350
gene id: 230089:VY86_RS08350
uniprot id: A0A0F7LJS5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Monomer.

230089:VY86 RS14425
gene id: 230089:VY86_RS14425
uniprot id: A0A0F7LP04
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 1 lipoyl cofactor covalently.
messages: E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).

230089:VY86 RS06485
gene id: 230089:VY86_RS06485
uniprot id: A0A0F7LIU1
names: Function
names: Similarity
messages: Belongs to the frataxin family.
messages: Involved in iron-sulfur (Fe-S) cluster assembly. May act as a regulator of Fe-S biogenesis.

230089:VY86 RS15380
gene id: 230089:VY86_RS15380
uniprot id: A0A0F7LRD2
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family.
messages: Homopolymer.
messages: Toroid-shaped homodecamer, composed of two pentamers of five dimers.

230089:VY86 RS03875
gene id: 230089:VY86_RS03875
uniprot id: A0A0F7LL28
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

230089:VY86 RS10220
gene id: 230089:VY86_RS10220
uniprot id: A0A0F7LPB7
names: Similarity
messages: Belongs to the cytochrome P450 family.

230089:VY86 RS11760
gene id: 230089:VY86_RS11760
uniprot id: A0A0F7LL22
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. Nitrilase family.

230089:VY86 RS13175
gene id: 230089:VY86_RS13175
uniprot id: A0A0F7LQF2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MreD family.
messages: Cell inner membrane
messages: Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins.
messages: Membrane

230089:VY86 RS15320
gene id: 230089:VY86_RS15320
uniprot id: A0A0F7LS00
names: Similarity
messages: Belongs to the LOG family.

230089:VY86 RS07150
gene id: 230089:VY86_RS07150
uniprot id: A0A0F7LJ45
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.

230089:VY86 RS00875
gene id: 230089:VY86_RS00875
uniprot id: A0A0F7LJ82
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.

230089:VY86 RS19570
gene id: 230089:VY86_RS19570
uniprot id: A0A0F7LTX1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid/polyamine transporter 2 family. Mtr/TnaB/TyrP permease subfamily.
messages: Cell inner membrane
messages: Involved in transporting aromatic amino acids across the cytoplasmic membrane.
messages: Membrane

230089:VY86 RS13365
gene id: 230089:VY86_RS13365
uniprot id: A0A0F7LQ74
names: Similarity
messages: Belongs to the glutamate synthase family.

230089:VY86 RS18030
gene id: 230089:VY86_RS18030
uniprot id: A0A0F7LSW8
names: Similarity
messages: Belongs to the Nudix hydrolase family. PCD1 subfamily.

230089:VY86 RS15235
gene id: 230089:VY86_RS15235
uniprot id: A0A0F7LRM3
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

230089:VY86 RS02625
gene id: 230089:VY86_RS02625
uniprot id: A0A0F7LI82
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase H family.
messages: Binds 1 Mg(2+) ion per subunit. May bind a second metal ion at a regulatory site, or after substrate binding.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Monomer.

230089:VY86 RS06910
gene id: 230089:VY86_RS06910
uniprot id: A0A0F7LMU4
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

230089:VY86 RS14530
gene id: 230089:VY86_RS14530
uniprot id: A0A0F7LQT1
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

230089:VY86 RS06515
gene id: 230089:VY86_RS06515
uniprot id: A0A0F7LK67
names: Subcellular Location Annotation
messages: Membrane

230089:VY86 RS06100
gene id: 230089:VY86_RS06100
uniprot id: A0A0F7LIK6
names: Similarity
messages: Belongs to the AB hydrolase superfamily. AB hydrolase 4 family.

230089:VY86 RS03105
gene id: 230089:VY86_RS03105
uniprot id: A0A0F7LII6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)- to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Homodimer.

230089:VY86 RS20775
gene id: 230089:VY86_RS20775
uniprot id: A0A0F7LT85
names: Similarity
messages: Belongs to the EndA/NucM nuclease family.

230089:VY86 RS21265
gene id: 230089:VY86_RS21265
uniprot id: A0A0F7LUD6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliQ/MopD/SpaQ family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

230089:VY86 RS01295
gene id: 230089:VY86_RS01295
uniprot id: A0A0F7LGB2
names: Similarity
messages: Belongs to the DNA polymerase HolA subunit family.

230089:VY86 RS04245
gene id: 230089:VY86_RS04245
uniprot id: A0A0F7LHS0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

230089:VY86 RS04900
gene id: 230089:VY86_RS04900
uniprot id: A0A0F7LLJ4
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

230089:VY86 RS05290
gene id: 230089:VY86_RS05290
uniprot id: A0A0F7LIA4
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

230089:VY86 RS04590
gene id: 230089:VY86_RS04590
uniprot id: A0A0F7LHZ2
names: Similarity
messages: Belongs to the SufE family.

230089:VY86 RS22095
gene id: 230089:VY86_RS22095
uniprot id: A0A0F7LVM4
names: Similarity
messages: Belongs to the peptidase S16 family.

230089:VY86 RS05580
gene id: 230089:VY86_RS05580
uniprot id: A0A0F7LLG4
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPAT/DAPAT family.
messages: Cell membrane
messages: The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate.

230089:VY86 RS21165
gene id: 230089:VY86_RS21165
uniprot id: A0A0F7LQI0
names: Function
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.
messages: In the C-terminal section; belongs to the aldehyde dehydrogenase family.
messages: In the N-terminal section; belongs to the proline dehydrogenase family.
messages: Oxidizes proline to glutamate for use as a carbon and nitrogen source.

230089:VY86 RS01370
gene id: 230089:VY86_RS01370
uniprot id: A0A0F7LV04
names: Function
names: Similarity
messages: Belongs to the NrdI family.
messages: Probably involved in ribonucleotide reductase function.

230089:VY86 RS17580
gene id: 230089:VY86_RS17580
uniprot id: A0A0F7LSJ0
names: Similarity
messages: Belongs to the SAICAR synthetase family.

230089:VY86 RS06670
gene id: 230089:VY86_RS06670
uniprot id: A0A0F7LMH4
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

230089:VY86 RS06105
gene id: 230089:VY86_RS06105
uniprot id: A0A0F7LR38
names: Similarity
messages: Belongs to the UPF0270 family.

230089:VY86 RS02745
gene id: 230089:VY86_RS02745
uniprot id: A0A0F7LKJ8
names: Subcellular Location Annotation
messages: Membrane

230089:VY86 RS13170
gene id: 230089:VY86_RS13170
uniprot id: A0A0F7LR98
names: Similarity
messages: Belongs to the MreC family.

230089:VY86 RS05225
gene id: 230089:VY86_RS05225
uniprot id: A0A0F7LLP0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methyltransferase superfamily. RsmC family.
messages: Cytoplasm
messages: Monomer.
messages: Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle.

230089:VY86 RS08070
gene id: 230089:VY86_RS08070
uniprot id: A0A0F7LJN6
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

230089:VY86 RS13310
gene id: 230089:VY86_RS13310
uniprot id: A0A0F7LQQ2
names: Similarity
messages: Belongs to the peptidase S1C family.

230089:VY86 RS21160
gene id: 230089:VY86_RS21160
uniprot id: A0A0F7LUC1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Catalyzes the sodium-dependent uptake of extracellular L-proline.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

230089:VY86 RS14575
gene id: 230089:VY86_RS14575
uniprot id: A0A0F7LR57
names: Similarity
messages: Belongs to the UPF0231 family.

230089:VY86 RS22080
gene id: 230089:VY86_RS22080
uniprot id: A0A0F7LQU2
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the outer membrane OOP (TC 1.B.6) superfamily. OmpA family.
messages: Cell outer membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Monomer and homodimer.
messages: The extracellular loops are most variable in sequence, and in some bacteria confer sensitivity to phage and/or colicins.
messages: With TolR probably plays a role in maintaining the position of the peptidoglycan cell wall in the periplasm. Acts as a porin with low permeability that allows slow penetration of small solutes; an internal gate slows down solute passage.

230089:VY86 RS06295
gene id: 230089:VY86_RS06295
uniprot id: A0A0F7LK60
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm

230089:VY86 RS09000
gene id: 230089:VY86_RS09000
uniprot id: A0A0F7LNM8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PstS family.
messages: Part of the ABC transporter complex PstSACB involved in phosphate import.
messages: The complex is composed of two ATP-binding proteins (PstB), two transmembrane proteins (PstC and PstA) and a solute-binding protein (PstS).

230089:VY86 RS12945
gene id: 230089:VY86_RS12945
uniprot id: A0A0F7LNL5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Homodimer. Forms a membrane-associated complex with FtsX.
messages: Part of the ABC transporter FtsEX involved in cellular division. Important for assembly or stability of the septal ring.

230089:VY86 RS05665
gene id: 230089:VY86_RS05665
uniprot id: A0A0F7LIE6
names: Similarity
messages: Belongs to the GARS family.

230089:VY86 RS13700
gene id: 230089:VY86_RS13700
uniprot id: A0A0F7LQC0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family. ParE type 1 subfamily.
messages: Heterotetramer composed of ParC and ParE.
messages: Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.

230089:VY86 RS18780
gene id: 230089:VY86_RS18780
uniprot id: A0A0F7LTA8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the selenophosphate synthase 1 family. Class I subfamily.
messages: Binds 1 Mg(2+) ion per monomer.
messages: Homodimer.
messages: Synthesizes selenophosphate from selenide and ATP.

230089:VY86 RS14385
gene id: 230089:VY86_RS14385
uniprot id: A0A0F7LQR5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ExbB/TolQ family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity. Required, with TolR, for the proton motive force-dependent activation of TolA and for TolA-Pal interaction.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

230089:VY86 RS08720
gene id: 230089:VY86_RS08720
uniprot id: A0A0F7LNI1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HsdR family.
messages: Subunit R is required for both nuclease and ATPase activities, but not for modification.
messages: The type I restriction/modification system is composed of three polypeptides R, M and S.

230089:VY86 RS15675
gene id: 230089:VY86_RS15675
uniprot id: A0A0F7LPU4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LolA family.
messages: Monomer.
messages: Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane).
messages: Periplasm

230089:VY86 RS18655
gene id: 230089:VY86_RS18655
uniprot id: A0A0F7LT78
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the peroxiredoxin family. Tpx subfamily.
messages: Homodimer.
messages: The active site is a conserved redox-active cysteine residue, the peroxidatic cysteine (C(P)), which makes the nucleophilic attack on the peroxide substrate. The peroxide oxidizes the C(P)-SH to cysteine sulfenic acid (C(P)-SOH), which then reacts with another cysteine residue, the resolving cysteine (C(R)), to form a disulfide bridge. The disulfide is subsequently reduced by an appropriate electron donor to complete the catalytic cycle. In this atypical 2-Cys peroxiredoxin, C(R) is present in the same subunit to form an intramolecular disulfide. The disulfide is subsequently reduced by thioredoxin.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

230089:VY86 RS10815
gene id: 230089:VY86_RS10815
uniprot id: A0A0F7LNY6
names: Function
names: Similarity
messages: Belongs to the esterase D family.
messages: Serine hydrolase involved in the detoxification of formaldehyde.

230089:VY86 RS20170
gene id: 230089:VY86_RS20170
uniprot id: A0A0F7LU41
names: Function
names: Similarity
messages: Belongs to the AlaDH/PNT family.
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

230089:VY86 RS07845
gene id: 230089:VY86_RS07845
uniprot id: A0A0F7LL01
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

230089:VY86 RS06555
gene id: 230089:VY86_RS06555
uniprot id: A0A0F7LIU7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 56 family.
messages: Catalyzes the synthesis of Und-PP-GlcNAc-ManNAcA-Fuc4NAc (Lipid III), the third lipid-linked intermediate involved in ECA synthesis.
messages: Cell inner membrane

230089:VY86 RS03545
gene id: 230089:VY86_RS03545
uniprot id: A0A0F7LHH5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.
messages: Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins.
messages: Cytoplasm

230089:VY86 RS17535
gene id: 230089:VY86_RS17535
uniprot id: A0A0F7LSU8
names: Similarity
messages: Belongs to the ArsC family.

230089:VY86 RS14120
gene id: 230089:VY86_RS14120
uniprot id: A0A0F7LNX4
names: Similarity
messages: Belongs to the PrpD family.

230089:VY86 RS06475
gene id: 230089:VY86_RS06475
uniprot id: A0A0F7LMJ2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.

230089:VY86 RS00760
gene id: 230089:VY86_RS00760
uniprot id: A0A0F7LJP4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

230089:VY86 RS00820
gene id: 230089:VY86_RS00820
uniprot id: A0A0F7LK23
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HscB family.
messages: Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA.
messages: Interacts with HscA and stimulates its ATPase activity. Interacts with IscU.

230089:VY86 RS14950
gene id: 230089:VY86_RS14950
uniprot id: A0A0F7LMF0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.
messages: Cell membrane
messages: Self-interacts. Interacts with FtsZ.

230089:VY86 RS00550
gene id: 230089:VY86_RS00550
uniprot id: A0A0F7LG35
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. Thiolase family.
messages: Catalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed.
messages: Cytoplasm
messages: Heterotetramer of two alpha chains (FadJ) and two beta chains (FadI).

230089:VY86 RS02450
gene id: 230089:VY86_RS02450
uniprot id: A0A0F7LGV0
names: Caution
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the thiamine-monophosphate kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate.

230089:VY86 RS04785
gene id: 230089:VY86_RS04785
uniprot id: A0A0F7LL57
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

230089:VY86 RS19865
gene id: 230089:VY86_RS19865
uniprot id: A0A0F7LRH8
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

230089:VY86 RS05710
gene id: 230089:VY86_RS05710
uniprot id: A0A0F7LM67
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).

230089:VY86 RS13420
gene id: 230089:VY86_RS13420
uniprot id: A0A0F7LQ82
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DoxX family.
messages: Membrane

230089:VY86 RS00900
gene id: 230089:VY86_RS00900
uniprot id: A0A0F7LJ87
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.
messages: In the N-terminal section; belongs to the transposase 2 family.

230089:VY86 RS03555
gene id: 230089:VY86_RS03555
uniprot id: A0A0F7LKY7
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruD family.
messages: Responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs.

230089:VY86 RS01435
gene id: 230089:VY86_RS01435
uniprot id: A0A0F7LK79
names: Subcellular Location Annotation
messages: Membrane

230089:VY86 RS04905
gene id: 230089:VY86_RS04905
uniprot id: A0A0F7LLS1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

230089:VY86 RS06090
gene id: 230089:VY86_RS06090
uniprot id: A0A0F7LMB8
names: Subcellular Location Annotation
messages: Membrane

230089:VY86 RS15650
gene id: 230089:VY86_RS15650
uniprot id: A0A0F7LPT9
names: Subcellular Location Annotation
messages: Membrane

230089:VY86 RS03090
gene id: 230089:VY86_RS03090
uniprot id: A0A0F7LKX9
names: Subcellular Location Annotation
messages: Membrane

230089:VY86 RS14275
gene id: 230089:VY86_RS14275
uniprot id: A0A0F7LNY8
names: Similarity
messages: In the C-terminal section; belongs to the anthranilate synthase component I family.

230089:VY86 RS20720
gene id: 230089:VY86_RS20720
uniprot id: A0A0F7LUB0
names: Similarity
messages: Belongs to the phD/YefM antitoxin family.

230089:VY86 RS17435
gene id: 230089:VY86_RS17435
uniprot id: A0A0F7LSG1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. MdtB subfamily.
messages: Cell inner membrane
messages: Part of a tripartite efflux system composed of MdtA, MdtB and MdtC. MdtB forms a heteromultimer with MdtC.

230089:VY86 RS04835
gene id: 230089:VY86_RS04835
uniprot id: A0A0F7LL63
names: Similarity
messages: Belongs to the DNA polymerase type-B family.

230089:VY86 RS18165
gene id: 230089:VY86_RS18165
uniprot id: A0A0F7LT02
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

230089:VY86 RS03775
gene id: 230089:VY86_RS03775
uniprot id: A0A0F7LIX5
names: Similarity
messages: Belongs to the VapB family.

230089:VY86 RS02685
gene id: 230089:VY86_RS02685
uniprot id: A0A0F7LIA0
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

230089:VY86 RS04550
gene id: 230089:VY86_RS04550
uniprot id: A0A0F7LLP2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
messages: Cell inner membrane

230089:VY86 RS03725
gene id: 230089:VY86_RS03725
uniprot id: A0A0F7LIW7
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

230089:VY86 RS02075
gene id: 230089:VY86_RS02075
uniprot id: A0A0F7LHY1
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

230089:VY86 RS02615
gene id: 230089:VY86_RS02615
uniprot id: A0A0F7LJW8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Monomer.
messages: Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl-glutathione to form glutathione and D-lactic acid.

230089:VY86 RS17510
gene id: 230089:VY86_RS17510
uniprot id: A0A0F7LSH4
names: Cofactor
messages: Binds 1 Mg(2+) ion per trimer.

230089:VY86 RS20215
gene id: 230089:VY86_RS20215
uniprot id: A0A0F7LRM4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fimbrial export usher family.
messages: Cell outer membrane
messages: Membrane

230089:VY86 RS21245
gene id: 230089:VY86_RS21245
uniprot id: A0A0F7LS77
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliM family.
messages: Cell inner membrane
messages: FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
messages: Membrane

230089:VY86 RS20715
gene id: 230089:VY86_RS20715
uniprot id: A0A0F7LU58
names: Similarity
messages: Belongs to the SIP oxidoreductase family.

230089:VY86 RS15185
gene id: 230089:VY86_RS15185
uniprot id: A0A0F7LRL9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily.
messages: Cell inner membrane
messages: Involved in the import of queuosine (Q) precursors, required for Q precursor salvage.

230089:VY86 RS03880
gene id: 230089:VY86_RS03880
uniprot id: A0A0F7LLA3
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Component of the RNA degradosome, which is a multiprotein complex involved in RNA processing and mRNA degradation.
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

230089:VY86 RS13260
gene id: 230089:VY86_RS13260
uniprot id: A0A0F7LQ60
names: Function
names: Similarity
names: Subunit
messages: Belongs to the KdsC family.
messages: Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate.
messages: Homotetramer.

230089:VY86 RS04975
gene id: 230089:VY86_RS04975
uniprot id: A0A0F7LL83
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

230089:VY86 RS10620
gene id: 230089:VY86_RS10620
uniprot id: A0A0F7LPH3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

230089:VY86 RS15175
gene id: 230089:VY86_RS15175
uniprot id: A0A0F7LMJ1
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily.
messages: Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl-L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway.

230089:VY86 RS12850
gene id: 230089:VY86_RS12850
uniprot id: A0A0F7LQ07
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FrdD family.
messages: Cell membrane
messages: Part of an enzyme complex containing four subunits: a flavoprotein (FrdA), an iron-sulfur protein (FrdB), and two hydrophobic anchor proteins (FrdC and FrdD).
messages: Two distinct, membrane-bound, FAD-containing enzymes are responsible for the catalysis of fumarate and succinate interconversion; fumarate reductase is used in anaerobic growth, and succinate dehydrogenase is used in aerobic growth. Anchors the catalytic components of the fumarate reductase complex to the cell inner membrane, binds quinones.

230089:VY86 RS15795
gene id: 230089:VY86_RS15795
uniprot id: A0A0F7LRJ0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial histone-like protein family.
messages: Heterodimer of an alpha and a beta chain.
messages: This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.

230089:VY86 RS05790
gene id: 230089:VY86_RS05790
uniprot id: A0A0F7LM75
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

230089:VY86 RS08240
gene id: 230089:VY86_RS08240
uniprot id: A0A0F7LMR8
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.
messages: Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems.

230089:VY86 RS04965
gene id: 230089:VY86_RS04965
uniprot id: A0A0F7LLS6
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

230089:VY86 RS01530
gene id: 230089:VY86_RS01530
uniprot id: A0A0F7LGE2
names: Function
names: Similarity
messages: Belongs to the class-I DAHP synthase family.
messages: Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP).

230089:VY86 RS05345
gene id: 230089:VY86_RS05345
uniprot id: A0A0F7LLE9
names: Caution
names: Similarity
messages: Belongs to the phosphoglycerate mutase family. GpmB subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

230089:VY86 RS04690
gene id: 230089:VY86_RS04690
uniprot id: A0A0F7LLP8
names: Subcellular Location Annotation
messages: Membrane

230089:VY86 RS09880
gene id: 230089:VY86_RS09880
uniprot id: A0A0F7LP31
names: Function
names: Similarity
messages: Belongs to the vsr family.
messages: May nick specific sequences that contain T:G mispairs resulting from m5C-deamination.

230089:VY86 RS13755
gene id: 230089:VY86_RS13755
uniprot id: A0A0F7LQW0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ExbD/TolR family.
messages: Cell inner membrane
messages: Cell membrane
messages: Involved in the TonB-dependent energy-dependent transport of various receptor-bound substrates.
messages: Membrane
messages: The accessory proteins ExbB and ExbD seem to form a complex with TonB.

230089:VY86 RS18190
gene id: 230089:VY86_RS18190
uniprot id: A0A0F7LT06
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Involved in the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (BtuD), two transmembrane proteins (BtuC) and a solute-binding protein (BtuF).

230089:VY86 RS16830
gene id: 230089:VY86_RS16830
uniprot id: A0A0F7LS37
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial microcompartment
messages: Belongs to the EutC family.
messages: Binds between the large and small subunits.
messages: Catalyzes the deamination of various vicinal amino-alcohols to oxo compounds. Allows this organism to utilize ethanolamine as the sole source of nitrogen and carbon in the presence of external vitamin B12.
messages: The basic unit is a heterodimer which dimerizes to form tetramers. The heterotetramers trimerize; 6 large subunits form a core ring with 6 small subunits projecting outwards.

230089:VY86 RS00845
gene id: 230089:VY86_RS00845
uniprot id: A0A0F7LK24
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.
messages: Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA.
messages: Cytoplasm
messages: Homodimer.

230089:VY86 RS17940
gene id: 230089:VY86_RS17940
uniprot id: A0A0F7LT40
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

230089:VY86 RS16170
gene id: 230089:VY86_RS16170
uniprot id: A0A0F7LRP9
names: Similarity
messages: Belongs to the phD/YefM antitoxin family.

230089:VY86 RS14405
gene id: 230089:VY86_RS14405
uniprot id: A0A0F7LR29
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

230089:VY86 RS04930
gene id: 230089:VY86_RS04930
uniprot id: A0A0F7LLS3
names: Function
names: Similarity
messages: Belongs to the ribF family.
messages: Catalyzes the phosphorylation of riboflavin to FMN followed by the adenylation of FMN to FAD.

230089:VY86 RS06500
gene id: 230089:VY86_RS06500
uniprot id: A0A0F7LMK6
names: Function
names: Similarity
messages: Belongs to the uroporphyrinogen-III synthase family.
messages: Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.

230089:VY86 RS13470
gene id: 230089:VY86_RS13470
uniprot id: A0A0F7LQ88
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IPP isomerase type 1 family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium ion binds only when substrate is bound.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP).
messages: Cytoplasm
messages: Homodimer.

230089:VY86 RS09650
gene id: 230089:VY86_RS09650
uniprot id: A0A0F7LP14
names: Function
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. Aliphatic amidase family.
messages: Is an aliphatic amidase with a restricted substrate specificity, as it only hydrolyzes formamide.

230089:VY86 RS00665
gene id: 230089:VY86_RS00665
uniprot id: A0A0F7LJ38
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

230089:VY86 RS21220
gene id: 230089:VY86_RS21220
uniprot id: A0A0F7LS71
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliH family.
messages: Cytoplasm
messages: Needed for flagellar regrowth and assembly.

230089:VY86 RS16425
gene id: 230089:VY86_RS16425
uniprot id: A0A0F7LS32
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily. UbiG/COQ3 family.
messages: O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway.

230089:VY86 RS15490
gene id: 230089:VY86_RS15490
uniprot id: A0A0F7LMN6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

230089:VY86 RS05780
gene id: 230089:VY86_RS05780
uniprot id: A0A0F7LJU7
names: Similarity
messages: Belongs to the disproportionating enzyme family.

230089:VY86 RS15860
gene id: 230089:VY86_RS15860
uniprot id: A0A0F7LMQ4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MukF family.
messages: Interacts, and probably forms a ternary complex, with MukE and MukB via its C-terminal region. The complex formation is stimulated by calcium or magnesium. It is required for an interaction between MukE and MukB.
messages: Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity.
messages: nucleoid

230089:VY86 RS18260
gene id: 230089:VY86_RS18260
uniprot id: A0A0F7LP32
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

230089:VY86 RS06325
gene id: 230089:VY86_RS06325
uniprot id: A0A0F7LMD8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-to-5' exoribonuclease specific for small oligoribonucleotides.
messages: Belongs to the oligoribonuclease family.
messages: Cytoplasm

230089:VY86 RS11085
gene id: 230089:VY86_RS11085
uniprot id: A0A0F7LKV5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane-bound acyltransferase family.
messages: Cell inner membrane
messages: Membrane

230089:VY86 RS04400
gene id: 230089:VY86_RS04400
uniprot id: A0A0F7LLM1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

230089:VY86 RS08110
gene id: 230089:VY86_RS08110
uniprot id: A0A0F7LN96
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Membrane

230089:VY86 RS09400
gene id: 230089:VY86_RS09400
uniprot id: A0A0F7LNG6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0126 family.
messages: Membrane

230089:VY86 RS18205
gene id: 230089:VY86_RS18205
uniprot id: A0A0F7LQY7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family.
messages: Catalyzes the transfer of 4-deoxy-4-formamido-L-arabinose from UDP to undecaprenyl phosphate. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides.
messages: Cell membrane

230089:VY86 RS20005
gene id: 230089:VY86_RS20005
uniprot id: A0A0F7LU15
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

230089:VY86 RS03750
gene id: 230089:VY86_RS03750
uniprot id: A0A0F7LIX1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DksA family.
messages: Cytoplasm
messages: Interacts directly with the RNA polymerase.
messages: Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters. Also required for regulation of fis expression.

230089:VY86 RS02495
gene id: 230089:VY86_RS02495
uniprot id: A0A0F7LKK8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

230089:VY86 RS21500
gene id: 230089:VY86_RS21500
uniprot id: A0A0F7LUR6
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.
messages: In the N-terminal section; belongs to the transposase 2 family.

230089:VY86 RS21405
gene id: 230089:VY86_RS21405
uniprot id: A0A0F7LQM8
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the flagella basal body rod proteins family.
messages: Secreted

230089:VY86 RS04365
gene id: 230089:VY86_RS04365
uniprot id: A0A0F7LLD1
names: Function
names: Similarity
messages: Belongs to the LpxB family.
messages: Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

230089:VY86 RS08150
gene id: 230089:VY86_RS08150
uniprot id: A0A0F7LL36
names: Similarity
names: Subunit
messages: Belongs to the ViaA family.
messages: Possible formation of a ternary complex RavA-ViaA-CadA.

230089:VY86 RS16695
gene id: 230089:VY86_RS16695
uniprot id: A0A0F7LRZ7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobD/CbiB family.
messages: Cell membrane
messages: Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

230089:VY86 RS14905
gene id: 230089:VY86_RS14905
uniprot id: A0A0F7LPA4
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

230089:VY86 RS19125
gene id: 230089:VY86_RS19125
uniprot id: A0A0F7LTQ4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

230089:VY86 RS22180
gene id: 230089:VY86_RS22180
uniprot id: A0A0F7LSN0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Gram-negative porin family.
messages: Cell outer membrane
messages: Homotrimer.
messages: Membrane

230089:VY86 RS16115
gene id: 230089:VY86_RS16115
uniprot id: A0A0F7LRP1
names: Subcellular Location Annotation
messages: Membrane

230089:VY86 RS14785
gene id: 230089:VY86_RS14785
uniprot id: A0A0F7LRN2
names: Function
names: Similarity
messages: Belongs to the arginase family. Agmatinase subfamily.
messages: Catalyzes the formation of putrescine from agmatine.

230089:VY86 RS21955
gene id: 230089:VY86_RS21955
uniprot id: A0A0F7LQT0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

230089:VY86 RS20905
gene id: 230089:VY86_RS20905
uniprot id: A0A0F7LUC6
names: Function
messages: Colicins are polypeptide toxins produced by and active against E.coli and closely related bacteria.

230089:VY86 RS08320
gene id: 230089:VY86_RS08320
uniprot id: A0A0F7LMS3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm
messages: Homodimer.

230089:VY86 RS04825
gene id: 230089:VY86_RS04825
uniprot id: A0A0F7LLI9
names: Similarity
messages: Belongs to the clavaminate synthase family.

230089:VY86 RS01330
gene id: 230089:VY86_RS01330
uniprot id: A0A0F7LJZ2
names: Function
names: Similarity
messages: Belongs to the peptidase S11 family.
messages: Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors.

230089:VY86 RS10200
gene id: 230089:VY86_RS10200
uniprot id: A0A0F7LNQ6
names: Subcellular Location Annotation
messages: Membrane

230089:VY86 RS21850
gene id: 230089:VY86_RS21850
uniprot id: A0A0F7LSH1
names: Subcellular Location Annotation
messages: Cytoplasm

230089:VY86 RS22035
gene id: 230089:VY86_RS22035
uniprot id: A0A0F7LUW9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dsrC/tusE family.
messages: Cytoplasm
messages: Interacts with the TusBCD complex. Interacts with MnmA.
messages: Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Could accept sulfur from TusD.

230089:VY86 RS13335
gene id: 230089:VY86_RS13335
uniprot id: A0A0F7LQQ4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

230089:VY86 RS20625
gene id: 230089:VY86_RS20625
uniprot id: A0A0F7LQ80
names: Similarity
messages: Belongs to the UPF0162 family.

230089:VY86 RS11410
gene id: 230089:VY86_RS11410
uniprot id: A0A0F7LKY6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SeqA family.
messages: Cytoplasm
messages: Homodimer. Polymerizes to form helical filaments.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re-initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated.

230089:VY86 RS17250
gene id: 230089:VY86_RS17250
uniprot id: A0A0F7LSD0
names: Caution
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 2 residues (Tyr-90 and Arg-93) present in a large hydrophobic pocket are probably involved in substrate specificity. They are important for desuccinylation activity, but dispensable for deacetylation activity.
messages: Belongs to the sirtuin family. Class III subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-dependent lysine deacetylase that specifically removes acetyl groups on target proteins. Also acts as a protein-lysine deacylase by mediating protein desuccinylation and de-2-hydroxyisobutyrylation. Modulates the activities of several proteins which are inactive in their acylated form.

230089:VY86 RS18510
gene id: 230089:VY86_RS18510
uniprot id: A0A0F7LR44
names: Similarity
messages: Belongs to the CFA/CMAS family.

230089:VY86 RS08250
gene id: 230089:VY86_RS08250
uniprot id: A0A0F7LL39
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

230089:VY86 RS11960
gene id: 230089:VY86_RS11960
uniprot id: A0A0F7LL92
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

230089:VY86 RS06230
gene id: 230089:VY86_RS06230
uniprot id: A0A0F7LK40
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PriB family.
messages: Binds single-stranded DNA at the primosome assembly site (PAS).
messages: Component of the preprimosomal complex composed of PriA, PriB, PriC, DnaB and DnaT. Upon transient interaction with DnaG it forms the primosome.

230089:VY86 RS12980
gene id: 230089:VY86_RS12980
uniprot id: A0A0F7LQE3
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

230089:VY86 RS18180
gene id: 230089:VY86_RS18180
uniprot id: A0A0F7LSU7
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

230089:VY86 RS14075
gene id: 230089:VY86_RS14075
uniprot id: A0A0F7LQP4
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

230089:VY86 RS14960
gene id: 230089:VY86_RS14960
uniprot id: A0A0F7LVF5
names: Function
names: Similarity
messages: Belongs to the LpxC family.
messages: Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.

230089:VY86 RS02780
gene id: 230089:VY86_RS02780
uniprot id: A0A0F7LK19
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

230089:VY86 RS04980
gene id: 230089:VY86_RS04980
uniprot id: A0A0F7LI58
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

230089:VY86 RS03995
gene id: 230089:VY86_RS03995
uniprot id: A0A0F7LKT2
names: Subcellular Location Annotation
messages: Membrane

230089:VY86 RS15415
gene id: 230089:VY86_RS15415
uniprot id: A0A0F7LPP3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0299 family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

230089:VY86 RS12025
gene id: 230089:VY86_RS12025
uniprot id: A0A0F7LN07
names: Function
names: Similarity
names: Subunit
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Monomer.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

230089:VY86 RS20400
gene id: 230089:VY86_RS20400
uniprot id: A0A0F7LTY4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

230089:VY86 RS12340
gene id: 230089:VY86_RS12340
uniprot id: A0A0F7LQE7
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

230089:VY86 RS02735
gene id: 230089:VY86_RS02735
uniprot id: A0A0F7LH04
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome c oxidase subunit 2 family.
messages: Cell membrane
messages: Cytochrome bo(3) ubiquinol terminal oxidase is the component of the aerobic respiratory chain of E.coli that predominates when cells are grown at high aeration. Has proton pump activity across the membrane in addition to electron transfer, pumping 2 protons/electron.
messages: Heterooctamer of two A chains, two B chains, two C chains and two D chains.
messages: Membrane

230089:VY86 RS02340
gene id: 230089:VY86_RS02340
uniprot id: A0A0F7LKG2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type III secretion exporter family.
messages: Membrane

230089:VY86 RS15790
gene id: 230089:VY86_RS15790
uniprot id: A0A0F7LS46
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS1 family.
messages: Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence.

230089:VY86 RS04540
gene id: 230089:VY86_RS04540
uniprot id: A0A0F7LJ93
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Xni family.
messages: Binds 1 K(+) per subunit. The potassium ion strongly increases the affinity for DNA.
messages: Binds 2 Mg(2+) per subunit. Only one magnesium ion has a direct interaction with the protein, the other interactions are indirect.
messages: Has flap endonuclease activity. During DNA replication, flap endonucleases cleave the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment.

230089:VY86 RS02530
gene id: 230089:VY86_RS02530
uniprot id: A0A0F7LGW2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SbcD family.
messages: Heterodimer of SbcC and SbcD.
messages: SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity.

230089:VY86 RS12455
gene id: 230089:VY86_RS12455
uniprot id: A0A0F7LPS5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family. QueF type 2 subfamily.
messages: Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
messages: Cytoplasm
messages: Homodimer.

230089:VY86 RS17375
gene id: 230089:VY86_RS17375
uniprot id: A0A0F7LNE0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the lipid A palmitoyltransferase family.
messages: Cell outer membrane
messages: Homodimer.
messages: Transfers a fatty acid residue from the sn-1 position of a phospholipid to the N-linked hydroxyfatty acid chain on the proximal unit of lipid A or its precursors.

230089:VY86 RS02470
gene id: 230089:VY86_RS02470
uniprot id: A0A0F7LKK7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

230089:VY86 RS17095
gene id: 230089:VY86_RS17095
uniprot id: A0A0F7LT22
names: Similarity
messages: Belongs to the UPF0265 family.

230089:VY86 RS02825
gene id: 230089:VY86_RS02825
uniprot id: A0A0F7LKR3
names: Subcellular Location Annotation
messages: Membrane

230089:VY86 RS12600
gene id: 230089:VY86_RS12600
uniprot id: A0A0F7LLI1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RdgC family.
messages: May be involved in recombination.
messages: nucleoid

230089:VY86 RS13965
gene id: 230089:VY86_RS13965
uniprot id: A0A0F7LK93
names: Similarity
messages: Belongs to the transposase 11 family.

230089:VY86 RS01570
gene id: 230089:VY86_RS01570
uniprot id: A0A0F7LK15
names: Subcellular Location Annotation
messages: Membrane

230089:VY86 RS05575
gene id: 230089:VY86_RS05575
uniprot id: A0A0F7LV58
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family.
messages: Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate.
messages: Cell inner membrane

230089:VY86 RS01180
gene id: 230089:VY86_RS01180
uniprot id: A0A0F7LJB8
names: Subcellular Location Annotation
messages: Membrane

230089:VY86 RS08075
gene id: 230089:VY86_RS08075
uniprot id: A0A0F7LL33
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
messages: Cytoplasm
messages: Homotrimer.
messages: In the C-terminal section; belongs to the transferase hexapeptide repeat family.
messages: In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.

230089:VY86 RS20045
gene id: 230089:VY86_RS20045
uniprot id: A0A0F7LPY1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

230089:VY86 RS02680
gene id: 230089:VY86_RS02680
uniprot id: A0A0F7LGZ8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

230089:VY86 RS00765
gene id: 230089:VY86_RS00765
uniprot id: A0A0F7LK05
names: Similarity
messages: In the C-terminal section; belongs to the transpeptidase family.
messages: In the N-terminal section; belongs to the glycosyltransferase 51 family.

230089:VY86 RS10380
gene id: 230089:VY86_RS10380
uniprot id: A0A0F7LPA5
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cell membrane
messages: Homodimer.
messages: May be involved in cell division.

230089:VY86 RS12845
gene id: 230089:VY86_RS12845
uniprot id: A0A0F7LV62
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

230089:VY86 RS00395
gene id: 230089:VY86_RS00395
uniprot id: A0A0F7LV19
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Membrane

230089:VY86 RS21445
gene id: 230089:VY86_RS21445
uniprot id: A0A0F7LUR0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

230089:VY86 RS20500
gene id: 230089:VY86_RS20500
uniprot id: A0A0F7LQ65
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0312 family. Type 1 subfamily.
messages: Periplasm

230089:VY86 RS15680
gene id: 230089:VY86_RS15680
uniprot id: A0A0F7LRW1
names: Function
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.
messages: DNA-dependent ATPase that plays important roles in cellular responses to stalled DNA replication processes.

230089:VY86 RS04950
gene id: 230089:VY86_RS04950
uniprot id: A0A0F7LJJ1
names: Subcellular Location Annotation
messages: Membrane

230089:VY86 RS13030
gene id: 230089:VY86_RS13030
uniprot id: A0A0F7LNM0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. PrmA family.
messages: Cytoplasm
messages: Methylates ribosomal protein L11.

230089:VY86 RS05695
gene id: 230089:VY86_RS05695
uniprot id: A0A0F7LR33
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Nudix hydrolase family. NudC subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Divalent metal cations. Mg(2+) or Mn(2+).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: mRNA decapping enzyme that specifically removes the nicotinamide adenine dinucleotide (NAD) cap from a subset of mRNAs by hydrolyzing the diphosphate linkage to produce nicotinamide mononucleotide (NMN) and 5' monophosphate mRNA. The NAD-cap is present at the 5'-end of some mRNAs and stabilizes RNA against 5'-processing. Has preference for mRNAs with a 5'-end purine. Catalyzes the hydrolysis of a broad range of dinucleotide pyrophosphates.

230089:VY86 RS17955
gene id: 230089:VY86_RS17955
uniprot id: A0A0F7LSW4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseA family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

230089:VY86 RS07000
gene id: 230089:VY86_RS07000
uniprot id: A0A0F7LML9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

230089:VY86 RS04945
gene id: 230089:VY86_RS04945
uniprot id: A0A0F7LI54
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

230089:VY86 RS05590
gene id: 230089:VY86_RS05590
uniprot id: A0A0F7LJQ8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S24 family.
messages: Homodimer.
messages: Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. Binds to the 16 bp palindromic sequence 5'-CTGTATATATATACAG-3'. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.

230089:VY86 RS11925
gene id: 230089:VY86_RS11925
uniprot id: A0A0F7LQ23
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrB/RnfD family.
messages: Cell membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

230089:VY86 RS18590
gene id: 230089:VY86_RS18590
uniprot id: A0A0F7LPB0
names: Function
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.
messages: Catalyzes the reduction of a carbon-carbon double bond in an enoyl moiety that is covalently linked to an acyl carrier protein (ACP). Involved in the elongation cycle of fatty acid which are used in the lipid metabolism and in the biotin biosynthesis.

230089:VY86 RS17210
gene id: 230089:VY86_RS17210
uniprot id: A0A0F7LQF8
names: Similarity
messages: Belongs to the peptidase S8 family.

230089:VY86 RS00655
gene id: 230089:VY86_RS00655
uniprot id: A0A0F7LJN0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).

230089:VY86 RS06795
gene id: 230089:VY86_RS06795
uniprot id: A0A0F7LKA3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

230089:VY86 RS05995
gene id: 230089:VY86_RS05995
uniprot id: A0A0F7LIH6
names: Similarity
messages: Belongs to the SlyX family.

230089:VY86 RS15215
gene id: 230089:VY86_RS15215
uniprot id: A0A0F7LRV0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MoaC family.
messages: Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
messages: Homohexamer; trimer of dimers.

230089:VY86 RS00930
gene id: 230089:VY86_RS00930
uniprot id: A0A0F7LG62
names: Similarity
messages: Belongs to the ner transcriptional regulatory family.

230089:VY86 RS13535
gene id: 230089:VY86_RS13535
uniprot id: A0A0F7LQV0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DHNA family.
messages: Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin.
messages: Homooctamer.

230089:VY86 RS19315
gene id: 230089:VY86_RS19315
uniprot id: A0A0F7LVD4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNR ribonuclease family. RNase II subfamily.
messages: Cytoplasm
messages: Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction.

230089:VY86 RS05585
gene id: 230089:VY86_RS05585
uniprot id: A0A0F7LIE4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial diacylglycerol kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of sn-l,2-diacylglycerol (DAG) to phosphatidic acid. Involved in the recycling of diacylglycerol produced as a by-product during membrane-derived oligosaccharide (MDO) biosynthesis.
messages: Cell inner membrane
messages: Membrane
messages: Mn(2+), Zn(2+), Cd(2+) and Co(2+) support activity to lesser extents.

230089:VY86 RS03595
gene id: 230089:VY86_RS03595
uniprot id: A0A0F7LKK3
names: Function
names: Similarity
messages: Belongs to the class-C beta-lactamase family.
messages: This protein is a serine beta-lactamase with a substrate specificity for cephalosporins.

230089:VY86 RS02455
gene id: 230089:VY86_RS02455
uniprot id: A0A0F7LI28
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

230089:VY86 RS01395
gene id: 230089:VY86_RS01395
uniprot id: A0A0F7LGC6
names: Similarity
messages: Belongs to the ABC transporter superfamily.

230089:VY86 RS02040
gene id: 230089:VY86_RS02040
uniprot id: A0A0F7LGN4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer.

230089:VY86 RS17330
gene id: 230089:VY86_RS17330
uniprot id: A0A0F7LQG7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell inner membrane
messages: Membrane

230089:VY86 RS13380
gene id: 230089:VY86_RS13380
uniprot id: A0A0F7LQI4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 51 family.
messages: Cell inner membrane
messages: Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors.

230089:VY86 RS14540
gene id: 230089:VY86_RS14540
uniprot id: A0A0F7LP40
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ribose 5-phosphate isomerase family.
messages: Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
messages: Homodimer.

230089:VY86 RS04175
gene id: 230089:VY86_RS04175
uniprot id: A0A0F7LLA4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAPS reductase family. CysH subfamily.
messages: Catalyzes the formation of sulfite from phosphoadenosine 5'-phosphosulfate (PAPS) using thioredoxin as an electron donor.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

230089:VY86 RS07145
gene id: 230089:VY86_RS07145
uniprot id: A0A0F7LM79
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

230089:VY86 RS02725
gene id: 230089:VY86_RS02725
uniprot id: A0A0F7LKP1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Cytochrome bo(3) ubiquinol terminal oxidase is the component of the aerobic respiratory chain of E.coli that predominates when cells are grown at high aeration. Has proton pump activity across the membrane in addition to electron transfer, pumping 2 protons/electron.
messages: Heterooctamer of two A chains, two B chains, two C chains and two D chains.
messages: Membrane

230089:VY86 RS15655
gene id: 230089:VY86_RS15655
uniprot id: A0A0F7LRV7
names: Subcellular Location Annotation
messages: Membrane

230089:VY86 RS01525
gene id: 230089:VY86_RS01525
uniprot id: A0A0F7LJE1
names: Subcellular Location Annotation
messages: Cytoplasm

230089:VY86 RS00870
gene id: 230089:VY86_RS00870
uniprot id: A0A0F7LK26
names: Subcellular Location Annotation
messages: Membrane

230089:VY86 RS16440
gene id: 230089:VY86_RS16440
uniprot id: A0A0F7LMY4
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the RcsB family.
messages: Component of the Rcs signaling system, which controls transcription of numerous genes. RcsB is the response regulator that binds to regulatory DNA regions.
messages: Interacts with RcsD.
messages: Phosphorylated and activated by RcsD.

230089:VY86 RS07515
gene id: 230089:VY86_RS07515
uniprot id: A0A0F7LN13
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

230089:VY86 RS13510
gene id: 230089:VY86_RS13510
uniprot id: A0A0F7LQU7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoD/SigA subfamily.
messages: Cytoplasm
messages: Interacts transiently with the RNA polymerase catalytic core.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.

230089:VY86 RS02045
gene id: 230089:VY86_RS02045
uniprot id: A0A0F7LHY0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

230089:VY86 RS01140
gene id: 230089:VY86_RS01140
uniprot id: A0A0F7LG96
names: Similarity
messages: Belongs to the glycosyl hydrolase 20 family.

230089:VY86 RS00635
gene id: 230089:VY86_RS00635
uniprot id: A0A0F7LJV7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ZipA family.
messages: Cell inner membrane
messages: Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins.
messages: Interacts with FtsZ via their C-terminal domains.

230089:VY86 RS06245
gene id: 230089:VY86_RS06245
uniprot id: A0A0F7LSX0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.
messages: Belongs to the RNR ribonuclease family. RNase R subfamily.
messages: Cytoplasm
messages: Monomer.

230089:VY86 RS06955
gene id: 230089:VY86_RS06955
uniprot id: A0A0F7LML5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

230089:VY86 RS13765
gene id: 230089:VY86_RS13765
uniprot id: A0A0F7LM10
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.
messages: In the N-terminal section; belongs to the transposase 2 family.

230089:VY86 RS15670
gene id: 230089:VY86_RS15670
uniprot id: A0A0F7LMP8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FtsK/SpoIIIE/SftA family.
messages: Membrane

230089:VY86 RS14525
gene id: 230089:VY86_RS14525
uniprot id: A0A0F7LRF0
names: Function
names: Similarity
names: Subunit
messages: Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division.
messages: Belongs to the ZapA family. Type 1 subfamily.
messages: Homodimer. Interacts with FtsZ.

230089:VY86 RS20685
gene id: 230089:VY86_RS20685
uniprot id: A0A0F7LRT9
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

230089:VY86 RS13200
gene id: 230089:VY86_RS13200
uniprot id: A0A0F7LQF3
names: Similarity
messages: Belongs to the peptidase U62 family.

230089:VY86 RS00365
gene id: 230089:VY86_RS00365
uniprot id: A0A0F7LUZ6
names: Caution
names: Function
names: Similarity
messages: Belongs to the UbiX/PAD1 family.
messages: Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

230089:VY86 RS10995
gene id: 230089:VY86_RS10995
uniprot id: A0A0F7LMK1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TrkH potassium transport family.
messages: Cell inner membrane
messages: Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA.
messages: Membrane

230089:VY86 RS12915
gene id: 230089:VY86_RS12915
uniprot id: A0A0F7LLQ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

230089:VY86 RS19065
gene id: 230089:VY86_RS19065
uniprot id: A0A0F7LTN1
names: Function
names: Similarity
messages: Belongs to the TrpC family.
messages: Belongs to the TrpF family.
messages: Bifunctional enzyme that catalyzes two sequential steps of tryptophan biosynthetic pathway. The first reaction is catalyzed by the isomerase, coded by the TrpF domain; the second reaction is catalyzed by the synthase, coded by the TrpC domain.
messages: In the C-terminal section; belongs to the TrpF family.
messages: In the N-terminal section; belongs to the TrpC family.

230089:VY86 RS15685
gene id: 230089:VY86_RS15685
uniprot id: A0A0F7LS36
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

230089:VY86 RS06000
gene id: 230089:VY86_RS06000
uniprot id: A0A0F7LJY8
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

230089:VY86 RS19180
gene id: 230089:VY86_RS19180
uniprot id: A0A0F7LTE2
names: Similarity
messages: Belongs to the VapB family.

230089:VY86 RS20165
gene id: 230089:VY86_RS20165
uniprot id: A0A0F7LTT2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PNT beta subunit family.
messages: Cell inner membrane
messages: Heterodimer of an alpha and a beta chain.
messages: Membrane
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

230089:VY86 RS17465
gene id: 230089:VY86_RS17465
uniprot id: A0A0F7LNE7
names: Function
names: PTM
names: Similarity
messages: An intermediate of this reaction is the autophosphorylated ppk in which a phosphate is covalently linked to a histidine residue through a N-P bond.
messages: Belongs to the polyphosphate kinase 1 (PPK1) family.
messages: Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP).

230089:VY86 RS05020
gene id: 230089:VY86_RS05020
uniprot id: A0A0F7LJJ9
names: Similarity
messages: Belongs to the ner transcriptional regulatory family.

230089:VY86 RS10520
gene id: 230089:VY86_RS10520
uniprot id: A0A0F7LNT6
names: Similarity
messages: Belongs to the UPF0213 family.

230089:VY86 RS18765
gene id: 230089:VY86_RS18765
uniprot id: A0A0F7LT86
names: Similarity
messages: Belongs to the asparaginase 1 family.

230089:VY86 RS07710
gene id: 230089:VY86_RS07710
uniprot id: A0A0F7LKT8
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

230089:VY86 RS19520
gene id: 230089:VY86_RS19520
uniprot id: A0A0F7LPP7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 5 family.
messages: Periplasm

230089:VY86 RS10975
gene id: 230089:VY86_RS10975
uniprot id: A0A0F7LPJ6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. Thiolase family.
messages: Catalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed.
messages: Cytoplasm
messages: Heterotetramer of two alpha chains (FadB) and two beta chains (FadA).

230089:VY86 RS10910
gene id: 230089:VY86_RS10910
uniprot id: A0A0F7LNZ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Membrane

230089:VY86 RS06150
gene id: 230089:VY86_RS06150
uniprot id: A0A0F7LM83
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
messages: Single-chain monomer with multiple functions.

230089:VY86 RS14210
gene id: 230089:VY86_RS14210
uniprot id: A0A0F7LM53
names: Similarity
messages: Belongs to the SdhE FAD assembly factor family.

230089:VY86 RS01300
gene id: 230089:VY86_RS01300
uniprot id: A0A0F7LHQ0
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

230089:VY86 RS15310
gene id: 230089:VY86_RS15310
uniprot id: A0A0F7LPN1
names: Similarity
messages: Belongs to the Dps family.

230089:VY86 RS17235
gene id: 230089:VY86_RS17235
uniprot id: A0A0F7LQG0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

230089:VY86 RS12805
gene id: 230089:VY86_RS12805
uniprot id: A0A0F7LNJ0
names: Similarity
messages: Belongs to the class-II fumarase/aspartase family. Aspartase subfamily.

230089:VY86 RS13785
gene id: 230089:VY86_RS13785
uniprot id: A0A0F7LQW2
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

230089:VY86 RS19805
gene id: 230089:VY86_RS19805
uniprot id: A0A0F7LPT3
names: Similarity
messages: Belongs to the Rpn/YhgA-like nuclease family.

230089:VY86 RS05300
gene id: 230089:VY86_RS05300
uniprot id: A0A0F7LJL1
names: Similarity
messages: Belongs to the Smp family.

230089:VY86 RS18105
gene id: 230089:VY86_RS18105
uniprot id: A0A0F7LT71
names: Subcellular Location Annotation
messages: Membrane

230089:VY86 RS03590
gene id: 230089:VY86_RS03590
uniprot id: A0A0F7LL68
names: Function
names: Similarity
messages: Belongs to the precorrin methyltransferase family.
messages: In the C-terminal section; belongs to the precorrin methyltransferase family.
messages: In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family.
messages: Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme.

230089:VY86 RS16095
gene id: 230089:VY86_RS16095
uniprot id: A0A0F7LMT2
names: Similarity
messages: Belongs to the Rpn/YhgA-like nuclease family.

230089:VY86 RS05630
gene id: 230089:VY86_RS05630
uniprot id: A0A0F7LM61
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MetA family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine.

230089:VY86 RS21420
gene id: 230089:VY86_RS21420
uniprot id: A0A0F7LUQ7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
messages: Bacterial flagellum basal body
messages: Belongs to the FlgH family.
messages: Cell outer membrane
messages: Membrane
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod.

230089:VY86 RS21725
gene id: 230089:VY86_RS21725
uniprot id: A0A0F7LQR1
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

230089:VY86 RS08935
gene id: 230089:VY86_RS08935
uniprot id: A0A0F7LJZ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.
messages: Cell inner membrane
messages: Membrane
messages: Probable transporter of a GTP-driven Fe(2+) uptake system.

230089:VY86 RS02165
gene id: 230089:VY86_RS02165
uniprot id: A0A0F7LV15
names: Similarity
messages: Belongs to the FGGY kinase family.

230089:VY86 RS17425
gene id: 230089:VY86_RS17425
uniprot id: A0A0F7LSF4
names: Subcellular Location Annotation
messages: Cell inner membrane

230089:VY86 RS21255
gene id: 230089:VY86_RS21255
uniprot id: A0A0F7LUN7
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliO/MopB family.
messages: Cell membrane

230089:VY86 RS02800
gene id: 230089:VY86_RS02800
uniprot id: A0A0F7LKR1
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

230089:VY86 RS08160
gene id: 230089:VY86_RS08160
uniprot id: A0A0F7LNB5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbsD / FucU family. RbsD subfamily.
messages: Catalyzes the interconversion of beta-pyran and beta-furan forms of D-ribose.
messages: Cytoplasm
messages: Homodecamer.

230089:VY86 RS18025
gene id: 230089:VY86_RS18025
uniprot id: A0A0F7LT50
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

230089:VY86 RS14185
gene id: 230089:VY86_RS14185
uniprot id: A0A0F7LM51
names: Similarity
messages: Belongs to the RecJ family.

230089:VY86 RS17200
gene id: 230089:VY86_RS17200
uniprot id: A0A0F7LSC2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 3 family. NagZ subfamily.
messages: Cytoplasm
messages: Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide-linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N-acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides.

230089:VY86 RS25315
gene id: 230089:VY86_RS25315
uniprot id: A0A0F7LJP9
names: Subcellular Location Annotation
messages: Membrane

230089:VY86 RS03110
gene id: 230089:VY86_RS03110
uniprot id: A0A0F7LKS2
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

230089:VY86 RS05555
gene id: 230089:VY86_RS05555
uniprot id: A0A0F7LIE2
names: Subcellular Location Annotation
messages: Membrane

230089:VY86 RS05155
gene id: 230089:VY86_RS05155
uniprot id: A0A0F7LLX4
names: Cofactor
names: Similarity
messages: Belongs to the alkaline phosphatase family.
messages: Binds 1 Mg(2+) ion.
messages: Binds 2 Zn(2+) ions.

230089:VY86 RS14360
gene id: 230089:VY86_RS14360
uniprot id: A0A0F7LQR2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CpoB family.
messages: Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division.
messages: Periplasm

230089:VY86 RS16940
gene id: 230089:VY86_RS16940
uniprot id: A0A0F7LQD4
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

230089:VY86 RS05515
gene id: 230089:VY86_RS05515
uniprot id: A0A0F7LM17
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

230089:VY86 RS09335
gene id: 230089:VY86_RS09335
uniprot id: A0A0F7LNG2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

230089:VY86 RS08590
gene id: 230089:VY86_RS08590
uniprot id: A0A0F7LMZ4
names: Function
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
messages: Catalyzes the reversible oxidative deamination of glutamate to alpha-ketoglutarate and ammonia.

230089:VY86 RS04445
gene id: 230089:VY86_RS04445
uniprot id: A0A0F7LJ84
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family.
messages: Cytoplasm
messages: Homotrimer.

230089:VY86 RS21105
gene id: 230089:VY86_RS21105
uniprot id: A0A0F7LU71
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.
messages: In the N-terminal section; belongs to the transposase 2 family.

230089:VY86 RS04420
gene id: 230089:VY86_RS04420
uniprot id: A0A0F7LJ78
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by GTP. Inhibited by UTP.
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

230089:VY86 RS01580
gene id: 230089:VY86_RS01580
uniprot id: A0A0F7LJG0
names: Similarity
messages: Belongs to the glutamate--cysteine ligase type 1 family. Type 1 subfamily.

230089:VY86 RS17920
gene id: 230089:VY86_RS17920
uniprot id: A0A0F7LSW2
names: Similarity
messages: Belongs to the ArsC family.

230089:VY86 RS13330
gene id: 230089:VY86_RS13330
uniprot id: A0A0F7LQH6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AFG1 ATPase family. ZapE subfamily.
messages: Cytoplasm
messages: Interacts with FtsZ.
messages: Reduces the stability of FtsZ polymers in the presence of ATP.

230089:VY86 RS04415
gene id: 230089:VY86_RS04415
uniprot id: A0A0F7LHT6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

230089:VY86 RS04800
gene id: 230089:VY86_RS04800
uniprot id: A0A0F7LLI8
names: Function
names: Similarity
messages: Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage.
messages: Belongs to the Nudix hydrolase family. RppH subfamily.

230089:VY86 RS08035
gene id: 230089:VY86_RS08035
uniprot id: A0A0F7LL31
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

230089:VY86 RS08600
gene id: 230089:VY86_RS08600
uniprot id: A0A0F7LL72
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

230089:VY86 RS06540
gene id: 230089:VY86_RS06540
uniprot id: A0A0F7LMG0
names: Subcellular Location Annotation
messages: Membrane

230089:VY86 RS15505
gene id: 230089:VY86_RS15505
uniprot id: A0A0F7LS20
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the C-terminal section; belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: In the N-terminal section; belongs to the histidinol-phosphatase family.

230089:VY86 RS10950
gene id: 230089:VY86_RS10950
uniprot id: A0A0F7LPJ2
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Homooctamer.

230089:VY86 RS18125
gene id: 230089:VY86_RS18125
uniprot id: A0A0F7LQY0
names: Similarity
messages: Belongs to the fructosamine kinase family.

230089:VY86 RS18530
gene id: 230089:VY86_RS18530
uniprot id: A0A0F7LT31
names: Function
names: Similarity
messages: Belongs to the glutaredoxin family. Monothiol subfamily.
messages: Monothiol glutaredoxin involved in the biogenesis of iron-sulfur clusters.

230089:VY86 RS18730
gene id: 230089:VY86_RS18730
uniprot id: A0A0F7LTA4
names: Function
names: Similarity
messages: Belongs to the DadA oxidoreductase family.
messages: Oxidative deamination of D-amino acids.

230089:VY86 RS11480
gene id: 230089:VY86_RS11480
uniprot id: A0A0F7LKZ0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IA subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system and for the release of the potassium ions to the cytoplasm.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

230089:VY86 RS18050
gene id: 230089:VY86_RS18050
uniprot id: A0A0F7LST1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S33 family.
messages: Cytoplasm

230089:VY86 RS06570
gene id: 230089:VY86_RS06570
uniprot id: A0A0F7LML3
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the WecD family.
messages: Catalyzes the acetylation of dTDP-fucosamine (dTDP-4-amino-4,6-dideoxy-D-galactose) to dTDP-Fuc4NAc, which is utilized in the biosynthesis of the enterobacterial common antigen (ECA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

230089:VY86 RS15840
gene id: 230089:VY86_RS15840
uniprot id: A0A0F7LPV4
names: Similarity
messages: Belongs to the UPF0434 family.

230089:VY86 RS02190
gene id: 230089:VY86_RS02190
uniprot id: A0A0F7LKG3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BexD/CtrA/VexA family.
messages: Cell outer membrane
messages: Membrane

230089:VY86 RS18635
gene id: 230089:VY86_RS18635
uniprot id: A0A0F7LTH5
names: Subcellular Location Annotation
messages: Membrane

230089:VY86 RS16250
gene id: 230089:VY86_RS16250
uniprot id: A0A0F7LRQ7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 6 family.
messages: Cell membrane
messages: Composed of 13 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

230089:VY86 RS02665
gene id: 230089:VY86_RS02665
uniprot id: A0A0F7LKM5
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

230089:VY86 RS10325
gene id: 230089:VY86_RS10325
uniprot id: A0A0F7LNR1
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

230089:VY86 RS16110
gene id: 230089:VY86_RS16110
uniprot id: A0A0F7LS94
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A24 family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Plays an essential role in type IV pili and type II pseudopili formation by proteolytically removing the leader sequence from substrate proteins and subsequently monomethylating the alpha-amino group of the newly exposed N-terminal phenylalanine.

230089:VY86 RS15560
gene id: 230089:VY86_RS15560
uniprot id: A0A0F7LRF9
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

230089:VY86 RS07850
gene id: 230089:VY86_RS07850
uniprot id: A0A0F7LV84
names: Similarity
messages: Belongs to the UPF0758 family. YicR subfamily.

230089:VY86 RS03745
gene id: 230089:VY86_RS03745
uniprot id: A0A0F7LHK3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. GluQ subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5-dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon.

230089:VY86 RS16245
gene id: 230089:VY86_RS16245
uniprot id: A0A0F7LSD5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 23 kDa subunit family.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell membrane
messages: NDH-1 is composed of 13 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

230089:VY86 RS05470
gene id: 230089:VY86_RS05470
uniprot id: A0A0F7LIC6
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.

230089:VY86 RS12550
gene id: 230089:VY86_RS12550
uniprot id: A0A0F7LNF5
names: Subcellular Location Annotation
messages: Membrane

230089:VY86 RS16915
gene id: 230089:VY86_RS16915
uniprot id: A0A0F7LQD2
names: Similarity
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane
messages: To H.influenzae HI_0842.

230089:VY86 RS14050
gene id: 230089:VY86_RS14050
uniprot id: A0A0F7LQM5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

230089:VY86 RS13450
gene id: 230089:VY86_RS13450
uniprot id: A0A0F7LLW1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Cell membrane
messages: Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

230089:VY86 RS12635
gene id: 230089:VY86_RS12635
uniprot id: A0A0F7LLI4
names: Subcellular Location Annotation
messages: Membrane

230089:VY86 RS08385
gene id: 230089:VY86_RS08385
uniprot id: A0A0F7LNC3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IgaA family.
messages: Cell inner membrane
messages: Membrane

230089:VY86 RS01105
gene id: 230089:VY86_RS01105
uniprot id: A0A0F7LJB3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. Protein-1 exporter (TC 3.A.1.109) family.
messages: Membrane

230089:VY86 RS08000
gene id: 230089:VY86_RS08000
uniprot id: A0A0F7LML8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

230089:VY86 RS13035
gene id: 230089:VY86_RS13035
uniprot id: A0A0F7LQE6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

230089:VY86 RS07715
gene id: 230089:VY86_RS07715
uniprot id: A0A0F7LN36
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

230089:VY86 RS04265
gene id: 230089:VY86_RS04265
uniprot id: A0A0F7LKW0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.
messages: Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.
messages: Cytoplasm
messages: Homodimer.

230089:VY86 RS08870
gene id: 230089:VY86_RS08870
uniprot id: A0A0F7LNM3
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.

230089:VY86 RS06715
gene id: 230089:VY86_RS06715
uniprot id: A0A0F7LK92
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

230089:VY86 RS06855
gene id: 230089:VY86_RS06855
uniprot id: A0A0F7LMT9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

230089:VY86 RS03485
gene id: 230089:VY86_RS03485
uniprot id: A0A0F7LKI7
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

230089:VY86 RS09435
gene id: 230089:VY86_RS09435
uniprot id: A0A0F7LLS2
names: Similarity
messages: Belongs to the RelB/DinJ antitoxin family.

230089:VY86 RS16995
gene id: 230089:VY86_RS16995
uniprot id: A0A0F7LN98
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0324 family.
messages: Membrane

230089:VY86 RS15990
gene id: 230089:VY86_RS15990
uniprot id: A0A0F7LPW9
names: Similarity
messages: Belongs to the myoviridae tail sheath protein family.

230089:VY86 RS00170
gene id: 230089:VY86_RS00170
uniprot id: A0A0F7LFZ1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

230089:VY86 RS02510
gene id: 230089:VY86_RS02510
uniprot id: A0A0F7LI63
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the gamma-glutamyltransferase family.
messages: Cleaved by autocatalysis into a large and a small subunit.
messages: This enzyme consists of two polypeptide chains, which are synthesized in precursor form from a single polypeptide.

230089:VY86 RS20235
gene id: 230089:VY86_RS20235
uniprot id: A0A0F7LQ19
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

230089:VY86 RS02640
gene id: 230089:VY86_RS02640
uniprot id: A0A0F7LKM0
names: Similarity
messages: Belongs to the ner transcriptional regulatory family.

230089:VY86 RS04740
gene id: 230089:VY86_RS04740
uniprot id: A0A0F7LJF2
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit contributes ATPase, 3'-5' helicase, exonuclease activity and loads RecA onto ssDNA.
messages: Belongs to the helicase family. UvrD subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotrimer of RecB, RecC and RecD. All subunits contribute to DNA-binding. Interacts with RecA.
messages: The C-terminal domain has nuclease activity and interacts with RecD. It interacts with RecA, facilitating its loading onto ssDNA.
messages: The N-terminal DNA-binding domain is a ssDNA-dependent ATPase and has ATP-dependent 3'-5' helicase function. This domain interacts with RecC.

230089:VY86 RS18495
gene id: 230089:VY86_RS18495
uniprot id: A0A0F7LTF8
names: Function
messages: Catalyzes the dismutation of two molecules of 6,7-dimethyl-8-ribityllumazine, resulting in the formation of riboflavin and 5-amino-6-(D-ribitylamino)uracil.

230089:VY86 RS01380
gene id: 230089:VY86_RS01380
uniprot id: A0A0F7LV82
names: Function
names: Similarity
messages: Belongs to the transposase 11 family.
messages: Involved in the transposition of the insertion sequence IS5.

230089:VY86 RS18770
gene id: 230089:VY86_RS18770
uniprot id: A0A0F7LPE8
names: Similarity
messages: Belongs to the peptidase S49 family.

230089:VY86 RS18155
gene id: 230089:VY86_RS18155
uniprot id: A0A0F7LSU4
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.

230089:VY86 RS16270
gene id: 230089:VY86_RS16270
uniprot id: A0A0F7LSD8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 2 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 13 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

230089:VY86 RS02195
gene id: 230089:VY86_RS02195
uniprot id: A0A0F7LKS9
names: Similarity
messages: Belongs to the transposase 11 family.

230089:VY86 RS13925
gene id: 230089:VY86_RS13925
uniprot id: A0A0F7LR12
names: Function
names: Similarity
messages: Belongs to the LuxC family.
messages: LuxC is the fatty acid reductase enzyme responsible for synthesis of the aldehyde substrate for the luminescent reaction catalyzed by luciferase.

230089:VY86 RS16720
gene id: 230089:VY86_RS16720
uniprot id: A0A0F7LS02
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

230089:VY86 RS12610
gene id: 230089:VY86_RS12610
uniprot id: A0A0F7LNH4
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.
messages: In the N-terminal section; belongs to the transposase 2 family.

230089:VY86 RS16260
gene id: 230089:VY86_RS16260
uniprot id: A0A0F7LQ32
names: Subcellular Location Annotation
messages: Membrane

230089:VY86 RS07655
gene id: 230089:VY86_RS07655
uniprot id: A0A0F7LN44
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

230089:VY86 RS08810
gene id: 230089:VY86_RS08810
uniprot id: A0A0F7LLB9
names: Function
names: Similarity
messages: Belongs to the mannonate dehydratase family.
messages: Catalyzes the dehydration of D-mannonate.

230089:VY86 RS01485
gene id: 230089:VY86_RS01485
uniprot id: A0A0F7LJE0
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

230089:VY86 RS10775
gene id: 230089:VY86_RS10775
uniprot id: A0A0F7LPH5
names: Cofactor
names: Similarity
messages: Belongs to the RtcB family.
messages: Binds 2 manganese ions per subunit.

230089:VY86 RS00700
gene id: 230089:VY86_RS00700
uniprot id: A0A0F7LSQ5
names: Similarity
messages: Belongs to the acetyltransferase family. YpeA subfamily.

230089:VY86 RS18415
gene id: 230089:VY86_RS18415
uniprot id: A0A0F7LM12
names: Similarity
messages: Belongs to the transposase 11 family.

230089:VY86 RS03720
gene id: 230089:VY86_RS03720
uniprot id: A0A0F7LHK0
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanD family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
messages: Cytoplasm
messages: Heterooctamer of four alpha and four beta subunits.
messages: Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus.

230089:VY86 RS08850
gene id: 230089:VY86_RS08850
uniprot id: A0A0F7LNI0
names: Similarity
names: Subunit
messages: Belongs to the KHG/KDPG aldolase family.
messages: Homotrimer.

230089:VY86 RS02630
gene id: 230089:VY86_RS02630
uniprot id: A0A0F7LKI3
names: Function
names: Subunit
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease.
messages: The DNA polymerase holoenzyme is a complex that contains 10 different types of subunits. These subunits are organized into 3 functionally essential subassemblies: the pol III core, the beta sliding clamp processivity factor and the clamp-loading complex. The pol III core (subunits alpha,epsilon and theta) contains the polymerase and the 3'-5' exonuclease proofreading activities. The polymerase is tethered to the template via the sliding clamp processivity factor. The clamp-loading complex assembles the beta processivity factor onto the primer template and plays a central role in the organization and communication at the replication fork. This complex contains delta, delta', psi and chi, and copies of either or both of two different DnaX proteins, gamma and tau.

230089:VY86 RS10870
gene id: 230089:VY86_RS10870
uniprot id: A0A0F7LVE7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Membrane

230089:VY86 RS08595
gene id: 230089:VY86_RS08595
uniprot id: A0A0F7LJU2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmJ family.
messages: Cytoplasm
messages: Specifically methylates the guanosine in position 1516 of 16S rRNA.

230089:VY86 RS01455
gene id: 230089:VY86_RS01455
uniprot id: A0A0F7LK04
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-II family.

230089:VY86 RS06235
gene id: 230089:VY86_RS06235
uniprot id: A0A0F7LMC2
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with bS18 to 16S ribosomal RNA.

230089:VY86 RS18470
gene id: 230089:VY86_RS18470
uniprot id: A0A0F7LR39
names: Similarity
messages: Belongs to the pyruvate kinase family.

230089:VY86 RS14685
gene id: 230089:VY86_RS14685
uniprot id: A0A0F7LR74
names: Similarity
messages: Belongs to the tRNA methyltransferase O family.

230089:VY86 RS00650
gene id: 230089:VY86_RS00650
uniprot id: A0A0F7LHF5
names: Subcellular Location Annotation
messages: Cytoplasm

230089:VY86 RS08005
gene id: 230089:VY86_RS08005
uniprot id: A0A0F7LJM7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

230089:VY86 RS04570
gene id: 230089:VY86_RS04570
uniprot id: A0A0F7LJ95
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily.
messages: Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA.
messages: Cytoplasm
messages: Monomer.

230089:VY86 RS16180
gene id: 230089:VY86_RS16180
uniprot id: A0A0F7LQ08
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Mg(2+). Can also accept Mn(2+).

230089:VY86 RS10170
gene id: 230089:VY86_RS10170
uniprot id: A0A0F7LPB5
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

230089:VY86 RS21820
gene id: 230089:VY86_RS21820
uniprot id: A0A0F7LSG8
names: Function
messages: Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors. CheA is autophosphorylated; it can transfer its phosphate group to either CheB or CheY.

230089:VY86 RS06950
gene id: 230089:VY86_RS06950
uniprot id: A0A0F7LKD3
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: Methylated by PrmB.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

230089:VY86 RS07810
gene id: 230089:VY86_RS07810
uniprot id: A0A0F7LJI6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FPG family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
messages: Monomer.

230089:VY86 RS00505
gene id: 230089:VY86_RS00505
uniprot id: A0A0F7LHD7
names: Subcellular Location Annotation
messages: Membrane

230089:VY86 RS22040
gene id: 230089:VY86_RS22040
uniprot id: A0A0F7LUM8
names: Similarity
messages: Belongs to the acylphosphatase family.

230089:VY86 RS00545
gene id: 230089:VY86_RS00545
uniprot id: A0A0F7LJ08
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the formation of a hydroxyacyl-CoA by addition of water on enoyl-CoA. Also exhibits 3-hydroxyacyl-CoA epimerase and 3-hydroxyacyl-CoA dehydrogenase activities.
messages: Cytoplasm
messages: Heterotetramer of two alpha chains (FadJ) and two beta chains (FadI).
messages: In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family.
messages: In the central section; belongs to the 3-hydroxyacyl-CoA dehydrogenase family.

230089:VY86 RS10190
gene id: 230089:VY86_RS10190
uniprot id: A0A0F7LP88
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

230089:VY86 RS02035
gene id: 230089:VY86_RS02035
uniprot id: A0A0F7LJM4
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

230089:VY86 RS16475
gene id: 230089:VY86_RS16475
uniprot id: A0A0F7LQ76
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

230089:VY86 RS08735
gene id: 230089:VY86_RS08735
uniprot id: A0A0F7LNH1
names: Similarity
messages: Belongs to the cytochrome P450 family.

230089:VY86 RS06340
gene id: 230089:VY86_RS06340
uniprot id: A0A0F7LLS7
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Prokaryotic type I sub-subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
messages: Cell membrane
messages: Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The autoendoproteolytic cleavage occurs by a canonical serine protease mechanism, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain. During this reaction, the Ser that is part of the protease active site of the proenzyme becomes the pyruvoyl prosthetic group, which constitutes an essential element of the active site of the mature decarboxylase.

230089:VY86 RS03020
gene id: 230089:VY86_RS03020
uniprot id: A0A0F7LK52
names: Subcellular Location Annotation
messages: Membrane

230089:VY86 RS19480
gene id: 230089:VY86_RS19480
uniprot id: A0A0F7LTJ7
names: Similarity
messages: Belongs to the PspA/IM30 family.

230089:VY86 RS08270
gene id: 230089:VY86_RS08270
uniprot id: A0A0F7LJQ1
names: Similarity
messages: Belongs to the UPF0276 family.

230089:VY86 RS04750
gene id: 230089:VY86_RS04750
uniprot id: A0A0F7LLQ0
names: Function
names: Similarity
names: Subunit
messages: A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild-type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity.
messages: Belongs to the RecC family.
messages: Heterotrimer of RecB, RecC and RecD. All subunits contribute to DNA-binding.

230089:VY86 RS08060
gene id: 230089:VY86_RS08060
uniprot id: A0A0F7LMQ7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

230089:VY86 RS04440
gene id: 230089:VY86_RS04440
uniprot id: A0A0F7LHW1
names: Activity Regulation
names: Caution
names: Domain
names: Function
names: Similarity
messages: Belongs to the GlnD family.
messages: Has four distinct domains: an N-terminal nucleotidyltransferase (NT) domain responsible for UTase activity, a central HD domain that encodes UR activity, and two C-terminal ACT domains that seem to have a role in glutamine sensing.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen metabolism.
messages: Uridylyltransferase (UTase) activity is inhibited by glutamine, while glutamine activates uridylyl-removing (UR) activity.

230089:VY86 RS01315
gene id: 230089:VY86_RS01315
uniprot id: A0A0F7LJC7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transpeptidase family. MrdA subfamily.
messages: Catalyzes cross-linking of the peptidoglycan cell wall.
messages: Cell inner membrane

230089:VY86 RS01355
gene id: 230089:VY86_RS01355
uniprot id: A0A0F7LHR0
names: Subcellular Location Annotation
messages: Cytoplasm

230089:VY86 RS16445
gene id: 230089:VY86_RS16445
uniprot id: A0A0F7LQ73
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RcsD family.
messages: Cell inner membrane
messages: Component of the Rcs signaling system, which controls transcription of numerous genes. RcsD is a phosphotransfer intermediate between the sensor kinase RcsC and the response regulator RcsB. It acquires a phosphoryl group from RcsC and transfers it to RcsB.
messages: Interacts with RcsC and RcsB.
messages: Phosphorylated by RcsC.

230089:VY86 RS02870
gene id: 230089:VY86_RS02870
uniprot id: A0A0F7LKM4
names: Subcellular Location Annotation
messages: Cell inner membrane

230089:VY86 RS17555
gene id: 230089:VY86_RS17555
uniprot id: A0A0F7LSH6
names: Subcellular Location Annotation
messages: Cytoplasm

230089:VY86 RS18210
gene id: 230089:VY86_RS18210
uniprot id: A0A0F7LSV0
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Bifunctional enzyme that catalyzes the oxidative decarboxylation of UDP-glucuronic acid (UDP-GlcUA) to UDP-4-keto-arabinose (UDP-Ara4O) and the addition of a formyl group to UDP-4-amino-4-deoxy-L-arabinose (UDP-L-Ara4N) to form UDP-L-4-formamido-arabinose (UDP-L-Ara4FN). The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides.
messages: Homohexamer, formed by a dimer of trimers.
messages: In the C-terminal section; belongs to the NAD(P)-dependent epimerase/dehydratase family. UDP-glucuronic acid decarboxylase subfamily.
messages: In the N-terminal section; belongs to the Fmt family. UDP-L-Ara4N formyltransferase subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

230089:VY86 RS10545
gene id: 230089:VY86_RS10545
uniprot id: A0A0F7LNT8
names: Similarity
messages: Belongs to the RutC family.

230089:VY86 RS17245
gene id: 230089:VY86_RS17245
uniprot id: A0A0F7LSQ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

230089:VY86 RS17440
gene id: 230089:VY86_RS17440
uniprot id: A0A0F7LNE4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
messages: Cell inner membrane
messages: Part of a tripartite efflux system composed of MdtA, MdtB and MdtC.

230089:VY86 RS04205
gene id: 230089:VY86_RS04205
uniprot id: A0A0F7LLA8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0294 family.
messages: Cytoplasm

230089:VY86 RS04260
gene id: 230089:VY86_RS04260
uniprot id: A0A0F7LLK9
names: Similarity
messages: Belongs to the tRNA methyltransferase O family.

230089:VY86 RS19080
gene id: 230089:VY86_RS19080
uniprot id: A0A0F7LRB1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the anthranilate synthase component I family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia.

230089:VY86 RS20385
gene id: 230089:VY86_RS20385
uniprot id: A0A0F7LTX6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M23B family.
messages: Membrane

230089:VY86 RS19295
gene id: 230089:VY86_RS19295
uniprot id: A0A0F7LPM6
names: Similarity
messages: Belongs to the myoviridae tail sheath protein family.

230089:VY86 RS21425
gene id: 230089:VY86_RS21425
uniprot id: A0A0F7LUH0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

230089:VY86 RS02180
gene id: 230089:VY86_RS02180
uniprot id: A0A0F7LHY5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the etk/wzc family.
messages: Cell inner membrane
messages: Membrane

230089:VY86 RS06860
gene id: 230089:VY86_RS06860
uniprot id: A0A0F7LSX2
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

230089:VY86 RS22100
gene id: 230089:VY86_RS22100
uniprot id: A0A0F7LUX7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thioester dehydratase family. FabA subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)-decenoyl-ACP. Can catalyze the dehydratase reaction for beta-hydroxyacyl-ACPs with saturated chain lengths up to 16:0, being most active on intermediate chain length.

230089:VY86 RS06280
gene id: 230089:VY86_RS06280
uniprot id: A0A0F7LMG9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Monomer.

230089:VY86 RS15060
gene id: 230089:VY86_RS15060
uniprot id: A0A0F7LPF9
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

230089:VY86 RS15645
gene id: 230089:VY86_RS15645
uniprot id: A0A0F7LMP7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L/F-transferase family.
messages: Cytoplasm
messages: Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.

230089:VY86 RS04630
gene id: 230089:VY86_RS04630
uniprot id: A0A0F7LL25
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetyltransferase family. ArgA subfamily.
messages: Cytoplasm
messages: Homohexamer.

230089:VY86 RS04665
gene id: 230089:VY86_RS04665
uniprot id: A0A0F7LI00
names: Similarity
messages: Belongs to the CapA family.

230089:VY86 RS16330
gene id: 230089:VY86_RS16330
uniprot id: A0A0F7LS27
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid/polyamine transporter 2 family. Mtr/TnaB/TyrP permease subfamily.
messages: Cell inner membrane
messages: Involved in transporting aromatic amino acids across the cytoplasmic membrane.
messages: Membrane

230089:VY86 RS18215
gene id: 230089:VY86_RS18215
uniprot id: A0A0F7LT96
names: Function
names: Similarity
messages: Belongs to the polysaccharide deacetylase family. ArnD deformylase subfamily.
messages: Catalyzes the deformylation of 4-deoxy-4-formamido-L-arabinose-phosphoundecaprenol to 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides.

230089:VY86 RS05945
gene id: 230089:VY86_RS05945
uniprot id: A0A0F7LIG7
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

230089:VY86 RS07090
gene id: 230089:VY86_RS07090
uniprot id: A0A0F7LMW7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase M20A family. ArgE subfamily.
messages: Binds 2 Zn(2+) or Co(2+) ions per subunit.
messages: Catalyzes the hydrolysis of the amide bond of N(2)-acetylated L-amino acids. Cleaves the acetyl group from N-acetyl-L-ornithine to form L-ornithine, an intermediate in L-arginine biosynthesis pathway, and a branchpoint in the synthesis of polyamines.
messages: Cytoplasm
messages: Homodimer.

230089:VY86 RS00645
gene id: 230089:VY86_RS00645
uniprot id: A0A0F7LG37
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

230089:VY86 RS18935
gene id: 230089:VY86_RS18935
uniprot id: A0A0F7LT99
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

230089:VY86 RS21400
gene id: 230089:VY86_RS21400
uniprot id: A0A0F7LUG7
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Secreted

230089:VY86 RS16690
gene id: 230089:VY86_RS16690
uniprot id: A0A0F7LT21
names: Domain
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the CobB/CbiA family.
messages: Belongs to the CobB/CobQ family. CobQ subfamily.
messages: Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source.
messages: Comprises of two domains. The C-terminal domain contains the binding site for glutamine and catalyzes the hydrolysis of this substrate to glutamate and ammonia. The N-terminal domain is anticipated to bind ATP and cobyrinate and catalyzes the ultimate synthesis of the diamide product. The ammonia produced via the glutaminase domain is probably translocated to the adjacent domain via a molecular tunnel, where it reacts with an activated intermediate.
messages: The a and c carboxylates of cobyrinate are activated for nucleophilic attack via formation of a phosphorylated intermediate by ATP. CbiA catalyzes first the amidation of the c-carboxylate, and then that of the a-carboxylate.

230089:VY86 RS20270
gene id: 230089:VY86_RS20270
uniprot id: A0A0F7LTW5
names: Function
names: Similarity
names: Subunit
messages: ATPase required for the correct placement of the division site. Cell division inhibitors MinC and MinD act in concert to form an inhibitor capable of blocking formation of the polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings.
messages: Belongs to the ParA family. MinD subfamily.
messages: Interacts with MinC and FtsZ.

230089:VY86 RS17370
gene id: 230089:VY86_RS17370
uniprot id: A0A0F7LSF0
names: Subcellular Location Annotation
messages: Membrane

230089:VY86 RS20530
gene id: 230089:VY86_RS20530
uniprot id: A0A0F7LT62
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurJ/MviN family.
messages: Cell inner membrane
messages: Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.
messages: Membrane

230089:VY86 RS13265
gene id: 230089:VY86_RS13265
uniprot id: A0A0F7LLT8
names: Similarity
names: Subunit
messages: Belongs to the SIS family. GutQ/KpsF subfamily.
messages: Homotetramer.

230089:VY86 RS10630
gene id: 230089:VY86_RS10630
uniprot id: A0A0F7LKQ8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M17 family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm
messages: Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.

230089:VY86 RS14415
gene id: 230089:VY86_RS14415
uniprot id: A0A0F7LQS0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

230089:VY86 RS18930
gene id: 230089:VY86_RS18930
uniprot id: A0A0F7LTK2
names: Similarity
messages: Belongs to the UDPGP type 2 family.

230089:VY86 RS09465
gene id: 230089:VY86_RS09465
uniprot id: A0A0F7LV82
names: Function
names: Similarity
messages: Belongs to the transposase 11 family.
messages: Involved in the transposition of the insertion sequence IS5.

230089:VY86 RS10960
gene id: 230089:VY86_RS10960
uniprot id: A0A0F7LP02
names: Similarity
messages: Belongs to the peptidase S51 family.

230089:VY86 RS04435
gene id: 230089:VY86_RS04435
uniprot id: A0A0F7LKZ6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

230089:VY86 RS11470
gene id: 230089:VY86_RS11470
uniprot id: A0A0F7LPT8
names: Subcellular Location Annotation
messages: Membrane

230089:VY86 RS01190
gene id: 230089:VY86_RS01190
uniprot id: A0A0F7LHN3
names: Cofactor
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. NagA family.
messages: Binds 1 divalent metal cation per subunit.

230089:VY86 RS04180
gene id: 230089:VY86_RS04180
uniprot id: A0A0F7LLK5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Alpha(8)-beta(8). The alpha component is a flavoprotein, the beta component is a hemoprotein.
messages: Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Binds 1 siroheme per subunit.
messages: Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate.

230089:VY86 RS01360
gene id: 230089:VY86_RS01360
uniprot id: A0A0F7LJZ5
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MGMT family.
messages: Cytoplasm
messages: Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
messages: This enzyme catalyzes only one turnover and therefore is not strictly catalytic. According to one definition, an enzyme is a biocatalyst that acts repeatedly and over many reaction cycles.

230089:VY86 RS05310
gene id: 230089:VY86_RS05310
uniprot id: A0A0F7LLY6
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

230089:VY86 RS13560
gene id: 230089:VY86_RS13560
uniprot id: A0A0F7LQR0
names: Function
names: Similarity
messages: Belongs to the GlnE family.
messages: Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell.

230089:VY86 RS22125
gene id: 230089:VY86_RS22125
uniprot id: A0A0F7LUY1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCF family. Uup subfamily.
messages: Cytoplasm
messages: Probably plays a role in ribosome assembly or function. May be involved in resolution of branched DNA intermediates that result from template switching in postreplication gaps. Binds DNA and has ATPase activity.

230089:VY86 RS01115
gene id: 230089:VY86_RS01115
uniprot id: A0A0F7LHM5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. Protein-1 exporter (TC 3.A.1.109) family.
messages: Membrane

230089:VY86 RS03000
gene id: 230089:VY86_RS03000
uniprot id: A0A0F7LH46
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

230089:VY86 RS06225
gene id: 230089:VY86_RS06225
uniprot id: A0A0F7LIS3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein bS6.

230089:VY86 RS15055
gene id: 230089:VY86_RS15055
uniprot id: A0A0F7LMI4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 2 lipoyl cofactors covalently.
messages: Forms a 24-polypeptide structural core with octahedral symmetry.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).

230089:VY86 RS09075
gene id: 230089:VY86_RS09075
uniprot id: A0A0F7LLH4
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

230089:VY86 RS10260
gene id: 230089:VY86_RS10260
uniprot id: A0A0F7LM45
names: Similarity
messages: Belongs to the ner transcriptional regulatory family.

230089:VY86 RS16500
gene id: 230089:VY86_RS16500
uniprot id: A0A0F7LMZ1
names: Similarity
messages: Belongs to the phage antitermination Q type 1 family.

230089:VY86 RS20525
gene id: 230089:VY86_RS20525
uniprot id: A0A0F7LQ68
names: Similarity
messages: Belongs to the thioesterase family.

230089:VY86 RS12820
gene id: 230089:VY86_RS12820
uniprot id: A0A0F7LQ05
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

230089:VY86 RS12265
gene id: 230089:VY86_RS12265
uniprot id: A0A0F7LN35
names: Cofactor
names: Function
names: Similarity
messages: Adenine glycosylase active on G-A mispairs. MutY also corrects error-prone DNA synthesis past GO lesions which are due to the oxidatively damaged form of guanine: 7,8-dihydro-8-oxoguanine (8-oxo-dGTP).
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.

230089:VY86 RS12970
gene id: 230089:VY86_RS12970
uniprot id: A0A0F7LR96
names: Similarity
messages: Belongs to the leucine-binding protein family.

230089:VY86 RS11735
gene id: 230089:VY86_RS11735
uniprot id: A0A0F7LMU5
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.
messages: In the N-terminal section; belongs to the transposase 2 family.

230089:VY86 RS16255
gene id: 230089:VY86_RS16255
uniprot id: A0A0F7LMV3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 13 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

230089:VY86 RS14125
gene id: 230089:VY86_RS14125
uniprot id: A0A0F7LQZ5
names: Similarity
messages: Belongs to the citrate synthase family.

230089:VY86 RS02280
gene id: 230089:VY86_RS02280
uniprot id: A0A0F7LHZ7
names: Subcellular Location Annotation
messages: Cytoplasm

230089:VY86 RS17415
gene id: 230089:VY86_RS17415
uniprot id: A0A0F7LNE2
names: Similarity
messages: Belongs to the UPF0339 family. Duplicated subfamily.

230089:VY86 RS03610
gene id: 230089:VY86_RS03610
uniprot id: A0A0F7LKZ1
names: Similarity
messages: Belongs to the SIS family. AgaS subfamily.

230089:VY86 RS12010
gene id: 230089:VY86_RS12010
uniprot id: A0A0F7LQ45
names: Similarity
messages: Belongs to the UPF0301 (AlgH) family.

230089:VY86 RS17965
gene id: 230089:VY86_RS17965
uniprot id: A0A0F7LNU1
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

230089:VY86 RS06610
gene id: 230089:VY86_RS06610
uniprot id: A0A0F7LK74
names: Similarity
messages: Belongs to the thioredoxin family.

230089:VY86 RS02460
gene id: 230089:VY86_RS02460
uniprot id: A0A0F7LKH6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.
messages: Forms an icosahedral capsid composed of 60 subunits, arranged as a dodecamer of pentamers.

230089:VY86 RS20590
gene id: 230089:VY86_RS20590
uniprot id: A0A0F7LTZ9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial luciferase oxidoreductase family.
messages: Heterodimer of an alpha and a beta chain.
messages: Light-emitting reaction in luminous bacteria.

230089:VY86 RS15640
gene id: 230089:VY86_RS15640
uniprot id: A0A0F7LRG7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

230089:VY86 RS19835
gene id: 230089:VY86_RS19835
uniprot id: A0A0F7LRH6
names: Cofactor
messages: Binds 2 manganese ions per subunit.

230089:VY86 RS21455
gene id: 230089:VY86_RS21455
uniprot id: A0A0F7LQN0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FlgA family.
messages: Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly.
messages: Periplasm

230089:VY86 RS03970
gene id: 230089:VY86_RS03970
uniprot id: A0A0F7LKS9
names: Similarity
messages: Belongs to the transposase 11 family.

230089:VY86 RS02570
gene id: 230089:VY86_RS02570
uniprot id: A0A0F7LKL3
names: Similarity
messages: Belongs to the isochorismate synthase family.

230089:VY86 RS10330
gene id: 230089:VY86_RS10330
uniprot id: A0A0F7LKH1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

230089:VY86 RS08830
gene id: 230089:VY86_RS08830
uniprot id: A0A0F7LJX7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

230089:VY86 RS16305
gene id: 230089:VY86_RS16305
uniprot id: A0A0F7LSE2
names: Caution
names: Function
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family. MenB subfamily.
messages: Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2-naphthoyl-CoA (DHNA-CoA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

230089:VY86 RS08480
gene id: 230089:VY86_RS08480
uniprot id: A0A0F7LND9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

230089:VY86 RS05810
gene id: 230089:VY86_RS05810
uniprot id: A0A0F7LJV3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

230089:VY86 RS14765
gene id: 230089:VY86_RS14765
uniprot id: A0A0F7LR20
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC41A transporter family.
messages: Membrane

230089:VY86 RS14555
gene id: 230089:VY86_RS14555
uniprot id: A0A0F7LQT5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LysE/ArgO transporter (TC 2.A.75) family.
messages: Cell membrane
messages: Involved in the export of arginine. Important to control the intracellular level of arginine and the correct balance between arginine and lysine.

230089:VY86 RS08395
gene id: 230089:VY86_RS08395
uniprot id: A0A0F7LMV9
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HSP33 family.
messages: Cytoplasm
messages: Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress.
messages: Under oxidizing conditions two disulfide bonds are formed involving the reactive cysteines. Under reducing conditions zinc is bound to the reactive cysteines and the protein is inactive.

230089:VY86 RS18540
gene id: 230089:VY86_RS18540
uniprot id: A0A0F7LR47
names: Cofactor
names: Similarity
messages: Belongs to the glyoxalase I family.
messages: Binds 1 zinc ion per subunit. In the homodimer, two zinc ions are bound between subunits.

230089:VY86 RS08115
gene id: 230089:VY86_RS08115
uniprot id: A0A0F7LMQ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase A chain family.
messages: Cell membrane
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

230089:VY86 RS02840
gene id: 230089:VY86_RS02840
uniprot id: A0A0F7LIC3
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

230089:VY86 RS17145
gene id: 230089:VY86_RS17145
uniprot id: A0A0F7LSP5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

230089:VY86 RS17140
gene id: 230089:VY86_RS17140
uniprot id: A0A0F7LSB7
names: Similarity
messages: Belongs to the fabD family.

230089:VY86 RS21840
gene id: 230089:VY86_RS21840
uniprot id: A0A0F7LUK8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FlhD family.
messages: Cytoplasm
messages: Functions in complex with FlhC as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region. Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes. Also regulates genes whose products function in a variety of physiological pathways.
messages: Homodimer; disulfide-linked. Forms a heterohexamer composed of two FlhC and four FlhD subunits. Each FlhC binds a FlhD dimer, forming a heterotrimer, and a hexamer assembles by dimerization of two heterotrimers.
messages: The C-terminal region contains a putative helix-turn-helix (HTH) motif, suggesting that this region may bind DNA.

230089:VY86 RS14265
gene id: 230089:VY86_RS14265
uniprot id: A0A0F7LQQ5
names: Subcellular Location Annotation
messages: Membrane

230089:VY86 RS15660
gene id: 230089:VY86_RS15660
uniprot id: A0A0F7LS33
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

230089:VY86 RS00825
gene id: 230089:VY86_RS00825
uniprot id: A0A0F7LJ76
names: Similarity
messages: Belongs to the HesB/IscA family.

230089:VY86 RS01895
gene id: 230089:VY86_RS01895
uniprot id: A0A0F7LJK2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamE family.
messages: Cell outer membrane
messages: Part of the Bam complex, which is composed of the outer membrane protein BamA, and four lipoproteins BamB, BamC, BamD and BamE.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

230089:VY86 RS14215
gene id: 230089:VY86_RS14215
uniprot id: A0A0F7LNY2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA-modifying YgfZ family.
messages: Cytoplasm
messages: Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication.

230089:VY86 RS10245
gene id: 230089:VY86_RS10245
uniprot id: A0A0F7LPB8
names: Function
names: Similarity
messages: Belongs to the MurCDEF family. Mpl subfamily.
messages: Reutilizes the intact tripeptide L-alanyl-gamma-D-glutamyl-meso-diaminopimelate by linking it to UDP-N-acetylmuramate.

230089:VY86 RS01910
gene id: 230089:VY86_RS01910
uniprot id: A0A0F7LK90
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

230089:VY86 RS14335
gene id: 230089:VY86_RS14335
uniprot id: A0A0F7LR13
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the quinolinate synthase family. Type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
messages: Cytoplasm

230089:VY86 RS12835
gene id: 230089:VY86_RS12835
uniprot id: A0A0F7LQA7
names: Similarity
messages: Belongs to the radical SAM superfamily. KamA family.

230089:VY86 RS06945
gene id: 230089:VY86_RS06945
uniprot id: A0A0F7LJ22
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

230089:VY86 RS10240
gene id: 230089:VY86_RS10240
uniprot id: A0A0F7LP91
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FBPase class 1 family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

230089:VY86 RS04805
gene id: 230089:VY86_RS04805
uniprot id: A0A0F7LLR3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 1 family.
messages: Periplasm

230089:VY86 RS16185
gene id: 230089:VY86_RS16185
uniprot id: A0A0F7LT19
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0208 family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

230089:VY86 RS21190
gene id: 230089:VY86_RS21190
uniprot id: A0A0F7LQI5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliS family.
messages: cytosol

230089:VY86 RS13370
gene id: 230089:VY86_RS13370
uniprot id: A0A0F7LLU7
names: PTM
names: Subcellular Location Annotation
messages: Activation requires a sequential transfer of a phosphate group from a His in the primary transmitter domain, to an Asp in the receiver domain and to a His in the secondary transmitter domain.
messages: Cell inner membrane

230089:VY86 RS20120
gene id: 230089:VY86_RS20120
uniprot id: A0A0F7LTV0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SIMIBI class G3E GTPase family. UreG subfamily.
messages: Cytoplasm
messages: Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG.
messages: Homodimer. UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

230089:VY86 RS08665
gene id: 230089:VY86_RS08665
uniprot id: A0A0F7LV82
names: Function
names: Similarity
messages: Belongs to the transposase 11 family.
messages: Involved in the transposition of the insertion sequence IS5.

230089:VY86 RS00625
gene id: 230089:VY86_RS00625
uniprot id: A0A0F7LHE9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family.
messages: Membrane

230089:VY86 RS08330
gene id: 230089:VY86_RS08330
uniprot id: A0A0F7LL44
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

230089:VY86 RS18625
gene id: 230089:VY86_RS18625
uniprot id: A0A0F7LR60
names: Similarity
messages: Belongs to the PspA/IM30 family.

230089:VY86 RS17530
gene id: 230089:VY86_RS17530
uniprot id: A0A0F7LT23
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaA family. HdA subfamily.
messages: Mediates the interaction of DNA replication inititator protein DnaA with DNA polymerase subunit beta sliding clamp (dnaN). Stimulates hydrolysis of ATP-DnaA to ADP-DnaA, rendering DnaA inactive for reinititation, a process called regulatory inhibition of DnaA or RIDA.
messages: The active form seems to be an ADP-bound monomer. Forms the RIDA complex (regulatory inactivation of DnaA) of ATP-DnaA, ADP-Hda and the DNA-loaded beta sliding clamp (dnaN).

230089:VY86 RS14580
gene id: 230089:VY86_RS14580
uniprot id: A0A0F7LRH7
names: Cofactor
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.
messages: Binds 1 [4Fe-4S] cluster per subunit.

230089:VY86 RS13820
gene id: 230089:VY86_RS13820
uniprot id: A0A0F7LQI2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family. DtpB subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Proton-dependent permease that transports di- and tripeptides.

230089:VY86 RS21730
gene id: 230089:VY86_RS21730
uniprot id: A0A0F7LSF6
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

230089:VY86 RS06300
gene id: 230089:VY86_RS06300
uniprot id: A0A0F7LV71
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueG family.
messages: Binds 2 [4Fe-4S] clusters per monomer.
messages: Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

230089:VY86 RS07510
gene id: 230089:VY86_RS07510
uniprot id: A0A0F7LKQ4
names: Subcellular Location Annotation
messages: Cell inner membrane