219594:RFX3
gene id: 219594:RFX3
uniprot id: A0A6J3EFM5
uniprot id: A0A6J3EKY5
names: Subcellular Location Annotation
messages: Nucleus

219594:LOC116500144
gene id: 219594:LOC116500144
uniprot id: A0A6J3EHW5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:TMSB15B
gene id: 219594:TMSB15B
uniprot id: A0A6J3DN68
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thymosin beta family.
messages: Plays an important role in the organization of the cytoskeleton. Binds to and sequesters actin monomers (G actin) and therefore inhibits actin polymerization.
messages: cytoskeleton

219594:ATPAF2
gene id: 219594:ATPAF2
uniprot id: A0A6J3DU73
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP12 family.
messages: Mitochondrion

219594:ATXN2
gene id: 219594:ATXN2
uniprot id: A0A6J3DTX1
uniprot id: A0A6J3DVS3
uniprot id: A0A6J3DVS8
uniprot id: A0A6J3DY16
uniprot id: A0A6J3DY20
uniprot id: A0A6J3DYS9
uniprot id: A0A6J3DZU3
uniprot id: A0A6J3DZU8
names: Similarity
messages: Belongs to the ataxin-2 family.

219594:SEC24C
gene id: 219594:SEC24C
uniprot id: A0A6J3D609
uniprot id: A0A6J3D989
uniprot id: A0A6J3DBE9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEC23/SEC24 family. SEC24 subfamily.
messages: COPII-coated vesicle membrane
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: cytosol

219594:PDLIM3
gene id: 219594:PDLIM3
uniprot id: A0A6J3CXG2
uniprot id: A0A6J3CXS2
names: Subcellular Location Annotation
messages: Z line

219594:AMOT
gene id: 219594:AMOT
uniprot id: A0A6J3DL12
names: Similarity
messages: Belongs to the angiomotin family.

219594:NDRG3
gene id: 219594:NDRG3
uniprot id: A0A6J3DRQ8
uniprot id: A0A6J3DXW7
names: Similarity
messages: Belongs to the NDRG family.

219594:LOC116497385
gene id: 219594:LOC116497385
uniprot id: A0A6J3E088
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the intercrine beta (chemokine CC) family.
messages: Secreted

219594:TMEM208
gene id: 219594:TMEM208
uniprot id: A0A6J3DLH1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM208 family.
messages: Endoplasmic reticulum membrane
messages: May function as a negative regulator of endoplasmic reticulum-stress induced autophagy.
messages: Membrane

219594:ALG2
gene id: 219594:ALG2
uniprot id: A0A6J3CF05
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase group 1 family.
messages: Mannosylates Man(2)GlcNAc(2)-dolichol diphosphate and Man(1)GlcNAc(2)-dolichol diphosphate to form Man(3)GlcNAc(2)-dolichol diphosphate.
messages: Membrane

219594:LOX
gene id: 219594:LOX
uniprot id: A0A6J3EJZ9
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lysyl oxidase family.
messages: Mediates the post-translational oxidative deamination of lysine residues on target proteins leading to the formation of deaminated lysine (allysine).
messages: The lysine tyrosylquinone cross-link (LTQ) is generated by condensation of the epsilon-amino group of a lysine with a topaquinone produced by oxidation of tyrosine.
messages: extracellular space

219594:RAB4A
gene id: 219594:RAB4A
uniprot id: A0A6J3CNN7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Cell membrane
messages: Protein transport.

219594:TMEM230
gene id: 219594:TMEM230
uniprot id: A0A6J3EDC2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM134/TMEM230 family.
messages: Early endosome
messages: Endosome
messages: Involved in trafficking and recycling of synaptic vesicles.
messages: Late endosome
messages: Membrane
messages: Recycling endosome
messages: autophagosome
messages: synaptic vesicle
messages: trans-Golgi network

219594:NCEH1
gene id: 219594:NCEH1
uniprot id: A0A6J3DEA2
names: Similarity
messages: Belongs to the 'GDXG' lipolytic enzyme family.

219594:CHL1
gene id: 219594:CHL1
uniprot id: A0A6J3DFU7
uniprot id: A0A6J3DFV2
uniprot id: A0A6J3DII7
uniprot id: A0A6J3DJT7
names: Similarity
messages: Belongs to the immunoglobulin superfamily. L1/neurofascin/NgCAM family.

219594:LOC116486476
gene id: 219594:LOC116486476
uniprot id: A0A6J3CI23
uniprot id: A0A6J3CJI5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome P450 family.
messages: Endoplasmic reticulum membrane

219594:IAH1
gene id: 219594:IAH1
uniprot id: A0A6J3CTW5
names: Function
names: Similarity
messages: Belongs to the 'GDSL' lipolytic enzyme family. IAH1 subfamily.
messages: Probable lipase.

219594:STXBP5L
gene id: 219594:STXBP5L
uniprot id: A0A6J3DGP2
uniprot id: A0A6J3DIA3
uniprot id: A0A6J3DIB1
uniprot id: A0A6J3DIX3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat L(2)GL family.
messages: Cell membrane
messages: Cytoplasm
messages: Membrane

219594:LOC116496205
gene id: 219594:LOC116496205
uniprot id: A0A6J3E0E1
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

219594:LOC116488123
gene id: 219594:LOC116488123
uniprot id: A0A6J3CTB5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IL-17 family.
messages: Secreted

219594:AQP8
gene id: 219594:AQP8
uniprot id: A0A6J3DWC6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

219594:SLC35F1
gene id: 219594:SLC35F1
uniprot id: A0A6J3CM77
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC35F solute transporter family.
messages: Membrane

219594:LOC116502145
gene id: 219594:LOC116502145
uniprot id: A0A6J3EKI7
names: Similarity
messages: Belongs to the Arg-specific ADP-ribosyltransferase family.

219594:LOC116496184
gene id: 219594:LOC116496184
uniprot id: A0A6J3DZA8
names: Similarity
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.

219594:GRHL1
gene id: 219594:GRHL1
uniprot id: A0A6J3CSB5
names: Subcellular Location Annotation
messages: Nucleus

219594:CCDC149
gene id: 219594:CCDC149
uniprot id: A0A6J3CVM5
uniprot id: A0A6J3CXX4
uniprot id: A0A6J3D1P1
names: Similarity
messages: Belongs to the CCDC149 family.

219594:LOC116491399
gene id: 219594:LOC116491399
uniprot id: A0A6J3D9P6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the V-ATPase e1/e2 subunit family.
messages: Membrane
messages: Subunit of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment.
messages: V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex.

219594:VPS26B
gene id: 219594:VPS26B
uniprot id: A0A6J3E6P4
names: Similarity
messages: Belongs to the VPS26 family.

219594:GK5
gene id: 219594:GK5
uniprot id: A0A6J3DFW0
names: Similarity
messages: Belongs to the FGGY kinase family.

219594:SLC22A18
gene id: 219594:SLC22A18
uniprot id: A0A6J3D2H8
names: Subcellular Location Annotation
messages: Membrane

219594:ARL6IP5
gene id: 219594:ARL6IP5
uniprot id: A0A6J3DGQ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRA1 family.
messages: Membrane

219594:SUSD6
gene id: 219594:SUSD6
uniprot id: A0A6J3CZL6
uniprot id: A0A6J3D1V6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:NRG2
gene id: 219594:NRG2
uniprot id: A0A6J3DSI8
uniprot id: A0A6J3DTN4
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the neuregulin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

219594:ACOT8
gene id: 219594:ACOT8
uniprot id: A0A6J3DY06
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

219594:FSHB
gene id: 219594:FSHB
uniprot id: A0A6J3D0P3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycoprotein hormones subunit beta family.
messages: Secreted

219594:NUP210L
gene id: 219594:NUP210L
uniprot id: A0A6J3E8X9
names: Similarity
messages: Belongs to the NUP210 family.

219594:PLIN1
gene id: 219594:PLIN1
uniprot id: A0A6J3DI32
names: Similarity
messages: Belongs to the perilipin family.

219594:FNBP1L
gene id: 219594:FNBP1L
uniprot id: A0A6J3D8S0
uniprot id: A0A6J3DEH8
uniprot id: A0A6J3DEQ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FNBP1 family.
messages: Cell membrane
messages: Cytoplasmic vesicle
messages: Membrane
messages: Vesicle
messages: cell cortex
messages: cytoskeleton

219594:C11H15orf65
gene id: 219594:C11H15orf65
uniprot id: A0A6J3DNG3
names: Subcellular Location Annotation
messages: cilium axoneme

219594:BBS7
gene id: 219594:BBS7
uniprot id: A0A6J3D245
names: Function
names: Subunit
messages: Part of BBSome complex.
messages: The BBSome complex is thought to function as a coat complex required for sorting of specific membrane proteins to the primary cilia. The BBSome complex is required for ciliogenesis but is dispensable for centriolar satellite function.

219594:METAP1
gene id: 219594:METAP1
uniprot id: A0A6J3CZ45
uniprot id: A0A6J3D074
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Cotranslationally removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val).

219594:INSR
gene id: 219594:INSR
uniprot id: A0A6J3E738
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. Insulin receptor subfamily.
messages: Membrane

219594:ZC3HC1
gene id: 219594:ZC3HC1
uniprot id: A0A6J3EQR3
uniprot id: A0A6J3ES06
names: Subcellular Location Annotation
messages: Nucleus

219594:LOC116497003
gene id: 219594:LOC116497003
uniprot id: A0A6J3E3E8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane

219594:CLCF1
gene id: 219594:CLCF1
uniprot id: A0A6J3D262
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IL-6 superfamily.
messages: Secreted

219594:PITPNM2
gene id: 219594:PITPNM2
uniprot id: A0A6J3DUV4
uniprot id: A0A6J3DYY5
uniprot id: A0A6J3DZQ2
uniprot id: A0A6J3E0S2
names: Similarity
messages: Belongs to the PtdIns transfer protein family. PI transfer class IIA subfamily.

219594:LOC116494976
gene id: 219594:LOC116494976
uniprot id: A0A6J3DSU8
names: Subcellular Location Annotation
messages: Secreted

219594:EYA1
gene id: 219594:EYA1
uniprot id: A0A6J3CJ98
uniprot id: A0A6J3CQ94
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HAD-like hydrolase superfamily. EYA family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Nucleus

219594:PTPRN2
gene id: 219594:PTPRN2
uniprot id: A0A6J3CLE1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Receptor class 8 subfamily.
messages: Membrane
messages: secretory vesicle membrane

219594:LOC116502355
gene id: 219594:LOC116502355
uniprot id: A0A6J3EQG7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2A family.
messages: Chromosome
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

219594:IGF2BP3
gene id: 219594:IGF2BP3
uniprot id: A0A6J3CJB7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRM IMP/VICKZ family.
messages: Cytoplasm

219594:SDHB
gene id: 219594:SDHB
uniprot id: A0A6J3E1F9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Binds 1 [3Fe-4S] cluster.
messages: Binds 1 [4Fe-4S] cluster.
messages: Iron-sulfur protein (IP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).
messages: Mitochondrion inner membrane

219594:EDNRB
gene id: 219594:EDNRB
uniprot id: A0A6J3CUF8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

219594:ANAPC1
gene id: 219594:ANAPC1
uniprot id: A0A6J3CPQ9
uniprot id: A0A6J3CS03
names: Similarity
messages: Belongs to the APC1 family.

219594:LOC116496513
gene id: 219594:LOC116496513
uniprot id: A0A6J3E0B8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SMP-30/CGR1 family.
messages: Cytoplasm

219594:MAP2K1
gene id: 219594:MAP2K1
uniprot id: A0A6J3DGM9
uniprot id: A0A6J3DKP4
names: Similarity
messages: Belongs to the protein kinase superfamily.

219594:CDH5
gene id: 219594:CDH5
uniprot id: A0A6J3DLR9
uniprot id: A0A6J3DQD1
names: Function
names: Subcellular Location Annotation
messages: Cadherins are calcium-dependent cell adhesion proteins.
messages: Cell membrane

219594:SYNE2
gene id: 219594:SYNE2
uniprot id: A0A6J3CYG6
uniprot id: A0A6J3D0Y8
uniprot id: A0A6J3D3F8
names: Similarity
messages: Belongs to the nesprin family.

219594:AGAP1
gene id: 219594:AGAP1
uniprot id: A0A6J3D412
uniprot id: A0A6J3D416
uniprot id: A0A6J3D6N1
uniprot id: A0A6J3D754
uniprot id: A0A6J3D759
uniprot id: A0A6J3D9C9
uniprot id: A0A6J3D9Y0
names: Similarity
messages: Belongs to the centaurin gamma-like family.

219594:ARTN
gene id: 219594:ARTN
uniprot id: A0A6J3D8Q6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TGF-beta family. GDNF subfamily.
messages: Secreted

219594:SEC23A
gene id: 219594:SEC23A
uniprot id: A0A6J3D4S7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEC23/SEC24 family. SEC23 subfamily.
messages: COPII-coated vesicle membrane
messages: Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: cytosol

219594:UTS2
gene id: 219594:UTS2
uniprot id: A0A6J3E5K6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the urotensin-2 family.
messages: Secreted

219594:LOC116499750
gene id: 219594:LOC116499750
uniprot id: A0A6J3E9U3
names: Similarity
names: Subunit
messages: Belongs to the avian keratin family.
messages: The avian keratins (F-ker, S-ker, C-ker and B-ker) are a complex mixture of very similar polypeptides.

219594:MRPL19
gene id: 219594:MRPL19
uniprot id: A0A6J3CPH8
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.

219594:CDK5R1
gene id: 219594:CDK5R1
uniprot id: A0A6J3EBD9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cyclin-dependent kinase 5 activator family.
messages: Cell membrane
messages: Membrane

219594:LAP3
gene id: 219594:LAP3
uniprot id: A0A6J3CYP1
names: Similarity
names: Subunit
messages: Belongs to the peptidase M17 family.
messages: Homohexamer.

219594:IGF2BP1
gene id: 219594:IGF2BP1
uniprot id: A0A6J3E6C1
uniprot id: A0A6J3E9C1
uniprot id: A0A6J3E9Y4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRM IMP/VICKZ family.
messages: Nucleus
messages: filopodium
messages: growth cone
messages: lamellipodium
messages: perinuclear region

219594:FAHD2B
gene id: 219594:FAHD2B
uniprot id: A0A6J3ED69
names: Similarity
messages: Belongs to the FAH family.

219594:UNC93A
gene id: 219594:UNC93A
uniprot id: A0A6J3CW14
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the unc-93 family.
messages: Membrane

219594:SMIM7
gene id: 219594:SMIM7
uniprot id: A0A6J3EC01
names: Similarity
messages: Belongs to the SMIM7 family.

219594:B3GAT1
gene id: 219594:B3GAT1
uniprot id: A0A6J3E236
uniprot id: A0A6J3E3H5
uniprot id: A0A6J3E6C4
uniprot id: A0A6J3E730
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 43 family.
messages: Golgi apparatus membrane
messages: Membrane

219594:TOB1
gene id: 219594:TOB1
uniprot id: A0A6J3DWJ9
names: Similarity
messages: Belongs to the BTG family.

219594:ING4
gene id: 219594:ING4
uniprot id: A0A6J3EPE9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ING family.
messages: Component of an histone acetyltransferase complex.
messages: Component of an histone acetyltransferase complex. Interacts with H3K4me3 and to a lesser extent with H3K4me2.
messages: Nucleus
messages: The PHD-type zinc finger mediates the binding to H3K4me3.

219594:SLC6A9
gene id: 219594:SLC6A9
uniprot id: A0A6J3DAT1
uniprot id: A0A6J3DDE5
uniprot id: A0A6J3DGG0
uniprot id: A0A6J3DGL9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. SLC6A9 subfamily.
messages: Cell membrane
messages: Membrane

219594:TET3
gene id: 219594:TET3
uniprot id: A0A6J3E857
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TET family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Chromosome
messages: Dioxygenase that catalyzes the conversion of the modified genomic base 5-methylcytosine (5mC) into 5-hydroxymethylcytosine (5hmC) and plays a key role in epigenetic chromatin reprogramming during embryonic development.
messages: The zinc ions have a structural role.

219594:SUMO2
gene id: 219594:SUMO2
uniprot id: A0A6J3DW33
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ubiquitin family. SUMO subfamily.
messages: Nucleus

219594:GPATCH11
gene id: 219594:GPATCH11
uniprot id: A0A6J3CQ80
uniprot id: A0A6J3CSF7
names: Similarity
messages: Belongs to the GPATCH11 family.

219594:CNOT8
gene id: 219594:CNOT8
uniprot id: A0A6J3DPD1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CAF1 family.
messages: Nucleus

219594:TSPAN19
gene id: 219594:TSPAN19
uniprot id: A0A6J3EK77
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

219594:ELOVL7
gene id: 219594:ELOVL7
uniprot id: A0A6J3EHQ2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELO family. ELOVL7 subfamily.
messages: Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme with higher activity toward C18 acyl-CoAs, especially C18:3(n-3) acyl-CoAs and C18:3(n-6)-CoAs. Also active toward C20:4-, C18:0-, C18:1-, C18:2- and C16:0-CoAs, and weakly toward C20:0-CoA. Little or no activity toward C22:0-, C24:0-, or C26:0-CoAs. May participate to the production of saturated and polyunsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

219594:LRRFIP1
gene id: 219594:LRRFIP1
uniprot id: A0A6J3D440
uniprot id: A0A6J3D6Q7
uniprot id: A0A6J3D6R1
uniprot id: A0A6J3D788
uniprot id: A0A6J3D793
uniprot id: A0A6J3D9G2
uniprot id: A0A6J3DA06
uniprot id: A0A6J3DA11
names: Similarity
messages: Belongs to the LRRFIP family.

219594:SLC9A3R1
gene id: 219594:SLC9A3R1
uniprot id: A0A6J3DXV6
names: Function
names: Subcellular Location Annotation
messages: Endomembrane system
messages: Scaffold protein that connects plasma membrane proteins with members of the ezrin/moesin/radixin family and thereby helps to link them to the actin cytoskeleton and to regulate their surface expression.

219594:LOC116486763
gene id: 219594:LOC116486763
uniprot id: A0A6J3CM22
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily.

219594:TPMT
gene id: 219594:TPMT
uniprot id: A0A6J3CD38
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TPMT family.

219594:AJAP1
gene id: 219594:AJAP1
uniprot id: A0A6J3E5P5
names: Subcellular Location Annotation
messages: Membrane

219594:LOC116499656
gene id: 219594:LOC116499656
uniprot id: A0A6J3E9H2
names: Similarity
names: Subunit
messages: Belongs to the avian keratin family.
messages: The avian keratins (F-ker, S-ker, C-ker and B-ker) are a complex mixture of very similar polypeptides.

219594:ANAPC10
gene id: 219594:ANAPC10
uniprot id: A0A6J3CWP0
uniprot id: A0A6J3CZ26
names: Function
names: Similarity
messages: Belongs to the APC10 family.
messages: Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin-protein ligase complex that controls progression through mitosis and the G1 phase of the cell cycle.

219594:CAMK4
gene id: 219594:CAMK4
uniprot id: A0A6J3EDR7
names: Similarity
messages: Belongs to the protein kinase superfamily.

219594:HMGB1
gene id: 219594:HMGB1
uniprot id: A0A6J3EJI3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HMGB family.
messages: Chromosome

219594:LOC116490152
gene id: 219594:LOC116490152
uniprot id: A0A6J3D3S0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

219594:CRKL
gene id: 219594:CRKL
uniprot id: A0A6J3DVN0
names: Similarity
messages: Belongs to the CRK family.

219594:DOCK5
gene id: 219594:DOCK5
uniprot id: A0A6J3EFM7
names: Similarity
messages: Belongs to the DOCK family.

219594:USP2
gene id: 219594:USP2
uniprot id: A0A6J3E7H1
uniprot id: A0A6J3E8V5
names: Similarity
messages: Belongs to the peptidase C19 family.

219594:FUT9
gene id: 219594:FUT9
uniprot id: A0A6J3CNE4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 10 family.
messages: Golgi stack membrane

219594:NAMPT
gene id: 219594:NAMPT
uniprot id: A0A6J3DBF4
uniprot id: A0A6J3DBG4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NAPRTase family.
messages: Cytoplasm
messages: Homodimer.
messages: Nucleus
messages: Secreted

219594:DPH5
gene id: 219594:DPH5
uniprot id: A0A6J3DF64
names: Function
names: Similarity
messages: Belongs to the diphthine synthase family.
messages: S-adenosyl-L-methionine-dependent methyltransferase that catalyzes four methylations of the modified target histidine residue in translation elongation factor 2 (EF-2), to form an intermediate called diphthine methyl ester. The four successive methylation reactions represent the second step of diphthamide biosynthesis.

219594:GPC5
gene id: 219594:GPC5
uniprot id: A0A6J3DVV4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glypican family.
messages: Cell membrane
messages: Cell surface proteoglycan.

219594:CNTNAP2
gene id: 219594:CNTNAP2
uniprot id: A0A6J3CKQ5
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the neurexin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: paranodal septate junction

219594:PPP6R3
gene id: 219594:PPP6R3
uniprot id: A0A6J3CZF0
uniprot id: A0A6J3CZP2
uniprot id: A0A6J3CZP6
names: Similarity
messages: Belongs to the SAPS family.

219594:SNCA
gene id: 219594:SNCA
uniprot id: A0A6J3D0Y9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synuclein family.
messages: Membrane
messages: Nucleus
messages: Secreted
messages: Synapse

219594:NIBAN2
gene id: 219594:NIBAN2
uniprot id: A0A6J3DYI1
names: Similarity
messages: Belongs to the Niban family.

219594:LOC116498297
gene id: 219594:LOC116498297
uniprot id: A0A6J3E5L2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

219594:FDXR
gene id: 219594:FDXR
uniprot id: A0A6J3E2M1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferredoxin--NADP reductase type 1 family.
messages: Mitochondrion
messages: Serves as the first electron transfer protein in all the mitochondrial P450 systems including cholesterol side chain cleavage in all steroidogenic tissues, steroid 11-beta hydroxylation in the adrenal cortex, 25-OH-vitamin D3-24 hydroxylation in the kidney, and sterol C-27 hydroxylation in the liver.

219594:THRAP3
gene id: 219594:THRAP3
uniprot id: A0A6J3E398
uniprot id: A0A6J3E886
names: Similarity
messages: Belongs to the BCLAF1/THRAP3 family.

219594:LOC116486602
gene id: 219594:LOC116486602
uniprot id: A0A6J3CNB0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome P450 family.
messages: Endoplasmic reticulum membrane

219594:MOS
gene id: 219594:MOS
uniprot id: A0A6J3CF01
names: Similarity
messages: Belongs to the protein kinase superfamily.

219594:EXOC2
gene id: 219594:EXOC2
uniprot id: A0A6J3CIE1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SEC5 family.
messages: Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.
messages: Component of the exocyst complex.

219594:ANAPC15
gene id: 219594:ANAPC15
uniprot id: A0A6J3DK67
names: Similarity
messages: Belongs to the APC15 family.

219594:FCF1
gene id: 219594:FCF1
uniprot id: A0A6J3D1Q0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UTP23/FCF1 family. FCF1 subfamily.
messages: nucleolus

219594:SPON2
gene id: 219594:SPON2
uniprot id: A0A6J3CX96
uniprot id: A0A6J3D0Q6
names: Subcellular Location Annotation
messages: extracellular matrix

219594:SH2B2
gene id: 219594:SH2B2
uniprot id: A0A6J3E4R2
names: Similarity
messages: Belongs to the SH2B adapter family.

219594:LGSN
gene id: 219594:LGSN
uniprot id: A0A6J3CN50
names: Similarity
messages: Belongs to the glutamine synthetase family.

219594:DOT1L
gene id: 219594:DOT1L
uniprot id: A0A6J3E6V6
uniprot id: A0A6J3EBD6
uniprot id: A0A6J3EBX0
uniprot id: A0A6J3EDI9
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. DOT1 family.
messages: Histone methyltransferase that specifically trimethylates histone H3 to form H3K79me3. This methylation is required for telomere silencing and for the pachytene checkpoint during the meiotic cell cycle by allowing the recruitment of RAD9 to double strand breaks. Nucleosomes are preferred as substrate compared to free histone.
messages: Histone methyltransferase. Methylates 'Lys-79' of histone H3.
messages: In contrast to other lysine histone methyltransferases, it does not contain a SET domain, suggesting the existence of another mechanism for methylation of lysine residues of histones.
messages: Nucleus

219594:OAT
gene id: 219594:OAT
uniprot id: A0A6J3DAZ3
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

219594:AGPAT3
gene id: 219594:AGPAT3
uniprot id: A0A6J3CXJ6
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.

219594:RAB11FIP3
gene id: 219594:RAB11FIP3
uniprot id: A0A6J3DTJ7
uniprot id: A0A6J3DUJ4
uniprot id: A0A6J3DVD7
names: Subcellular Location Annotation
messages: Cleavage furrow
messages: Endosome membrane
messages: Membrane
messages: Midbody
messages: Recycling endosome membrane

219594:PTTG1
gene id: 219594:PTTG1
uniprot id: A0A6J3DSX4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the securin family.
messages: Cytoplasm
messages: Nucleus

219594:LCORL
gene id: 219594:LCORL
uniprot id: A0A6J3CYJ0
names: Subcellular Location Annotation
messages: Nucleus

219594:CSNK1A1
gene id: 219594:CSNK1A1
uniprot id: A0A6J3DPJ9
uniprot id: A0A6J3DRK7
uniprot id: A0A6J3DSD6
uniprot id: A0A6J3DTH9
names: Similarity
messages: Belongs to the protein kinase superfamily.

219594:TMED7
gene id: 219594:TMED7
uniprot id: A0A6J3EEU0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EMP24/GP25L family.
messages: Endoplasmic reticulum membrane
messages: Endoplasmic reticulum-Golgi intermediate compartment membrane
messages: Membrane
messages: cis-Golgi network membrane

219594:LOC116487147
gene id: 219594:LOC116487147
uniprot id: A0A6J3CL08
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

219594:HSD17B12
gene id: 219594:HSD17B12
uniprot id: A0A6J3D192
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

219594:APOC3
gene id: 219594:APOC3
uniprot id: A0A6J3E206
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the apolipoprotein C3 family.
messages: Secreted

219594:NUTF2
gene id: 219594:NUTF2
uniprot id: A0A6J3DPD4
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Has a role in nuclear-cytoplasmic transport of proteins and mRNAs.
messages: Nucleus

219594:MYO18B
gene id: 219594:MYO18B
uniprot id: A0A6J3DZ55
names: Caution
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:PMP22
gene id: 219594:PMP22
uniprot id: A0A6J3E0L3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PMP-22/EMP/MP20 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Might be involved in growth regulation, and in myelinization in the peripheral nervous system.

219594:KCNJ5
gene id: 219594:KCNJ5
uniprot id: A0A6J3E3N8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family. KCNJ5 subfamily.
messages: Membrane

219594:ATP5MC3
gene id: 219594:ATP5MC3
uniprot id: A0A6J3DAC8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Membrane
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain. A homomeric c-ring of probably 10 subunits is part of the complex rotary element.
messages: Mitochondrion membrane

219594:RAB3A
gene id: 219594:RAB3A
uniprot id: A0A6J3ECQ4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Cell membrane
messages: Protein transport. Probably involved in vesicular traffic.

219594:CCND2
gene id: 219594:CCND2
uniprot id: A0A6J3DKL4
names: Similarity
messages: Belongs to the cyclin family.

219594:ITFG1
gene id: 219594:ITFG1
uniprot id: A0A6J3DPG6
names: Similarity
messages: Belongs to the TIP family.

219594:CTSZ
gene id: 219594:CTSZ
uniprot id: A0A6J3DXL8
names: Similarity
messages: Belongs to the peptidase C1 family.

219594:PRKDC
gene id: 219594:PRKDC
uniprot id: A0A6J3CF16
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PI3/PI4-kinase family.
messages: nucleolus

219594:CREM
gene id: 219594:CREM
uniprot id: A0A6J3CGF7
uniprot id: A0A6J3CI08
uniprot id: A0A6J3CJ29
uniprot id: A0A6J3CL02
uniprot id: A0A6J3CMN2
names: Subcellular Location Annotation
messages: Nucleus

219594:TPK1
gene id: 219594:TPK1
uniprot id: A0A6J3CI69
uniprot id: A0A6J3CJM7
uniprot id: A0A6J3CP91
names: Similarity
messages: Belongs to the thiamine pyrophosphokinase family.

219594:USP33
gene id: 219594:USP33
uniprot id: A0A6J3D9E0
uniprot id: A0A6J3DC28
uniprot id: A0A6J3DD15
uniprot id: A0A6J3DF47
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C19 family. USP20/USP33 subfamily.
messages: centrosome
messages: perinuclear region

219594:FZD4
gene id: 219594:FZD4
uniprot id: A0A6J3ENK3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor Fz/Smo family.
messages: Cell membrane
messages: Membrane

219594:LOC116499887
gene id: 219594:LOC116499887
uniprot id: A0A6J3EFD4
names: Subcellular Location Annotation
messages: Membrane

219594:ACVRL1
gene id: 219594:ACVRL1
uniprot id: A0A6J3EC83
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
messages: Membrane

219594:ADGRF5
gene id: 219594:ADGRF5
uniprot id: A0A6J3CTD8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 2 family. Adhesion G-protein coupled receptor (ADGR) subfamily.
messages: Membrane

219594:UBE4B
gene id: 219594:UBE4B
uniprot id: A0A6J3E5X1
uniprot id: A0A6J3E706
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ubiquitin conjugation factor E4 family.
messages: Cytoplasm

219594:HIF1A
gene id: 219594:HIF1A
uniprot id: A0A6J3D7D9
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

219594:DRAM1
gene id: 219594:DRAM1
uniprot id: A0A6J3DTW1
names: Subcellular Location Annotation
messages: Membrane

219594:LOC116501451
gene id: 219594:LOC116501451
uniprot id: A0A6J3ELY7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

219594:DYNC1LI2
gene id: 219594:DYNC1LI2
uniprot id: A0A6J3DMU4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes.
messages: Belongs to the dynein light intermediate chain family.
messages: Homodimer. The cytoplasmic dynein 1 complex consists of two catalytic heavy chains (HCs) and a number of non-catalytic subunits presented by intermediate chains (ICs).
messages: cytoskeleton

219594:RNF20
gene id: 219594:RNF20
uniprot id: A0A6J3EL17
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BRE1 family.
messages: Nucleus

219594:COG2
gene id: 219594:COG2
uniprot id: A0A6J3CRM5
names: Similarity
messages: Belongs to the COG2 family.

219594:SLC7A10
gene id: 219594:SLC7A10
uniprot id: A0A6J3DQT3
names: Subcellular Location Annotation
messages: Membrane

219594:LOC116500797
gene id: 219594:LOC116500797
uniprot id: A0A6J3EDZ4
uniprot id: A0A6J3EKQ6
names: Similarity
messages: Belongs to the cystatin family.

219594:PTAFR
gene id: 219594:PTAFR
uniprot id: A0A6J3EA31
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Interacts with ARRB1.
messages: Membrane

219594:MOV10
gene id: 219594:MOV10
uniprot id: A0A6J3E9X2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA2/NAM7 helicase family. SDE3 subfamily.
messages: P-body

219594:RCAN3
gene id: 219594:RCAN3
uniprot id: A0A6J3E802
names: Similarity
messages: Belongs to the RCAN family.

219594:NGF
gene id: 219594:NGF
uniprot id: A0A6J3E5N2
uniprot id: A0A6J3EA46
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NGF-beta family.
messages: Secreted

219594:RORB
gene id: 219594:RORB
uniprot id: A0A6J3EJM0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

219594:RORA
gene id: 219594:RORA
uniprot id: A0A6J3DIU3
uniprot id: A0A6J3DK56
uniprot id: A0A6J3DM70
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

219594:CA14
gene id: 219594:CA14
uniprot id: A0A6J3EE70
names: Similarity
messages: Belongs to the alpha-carbonic anhydrase family.

219594:MERTK
gene id: 219594:MERTK
uniprot id: A0A6J3CRV5
uniprot id: A0A6J3CU71
uniprot id: A0A6J3CVA9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family.
messages: Membrane

219594:PDE4C
gene id: 219594:PDE4C
uniprot id: A0A6J3E7V0
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family. PDE4 subfamily.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

219594:EVX1
gene id: 219594:EVX1
uniprot id: A0A6J3CDP6
names: Subcellular Location Annotation
messages: Nucleus

219594:KDM4B
gene id: 219594:KDM4B
uniprot id: A0A6J3E712
uniprot id: A0A6J3E8J2
uniprot id: A0A6J3EBK8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the JHDM3 histone demethylase family.
messages: Nucleus

219594:TAC3
gene id: 219594:TAC3
uniprot id: A0A6J3EBN8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tachykinin family.
messages: Secreted

219594:EZR
gene id: 219594:EZR
uniprot id: A0A6J3CVK4
uniprot id: A0A6J3CWQ7
names: Subcellular Location Annotation
messages: Membrane
messages: cytoskeleton

219594:LOC116494122
gene id: 219594:LOC116494122
uniprot id: A0A6J3DQY2
names: Similarity
messages: Belongs to the cytochrome b5 family.

219594:LOC116491659
gene id: 219594:LOC116491659
uniprot id: A0A6J3DB30
names: Subcellular Location Annotation
messages: Secreted

219594:LOC116499643
gene id: 219594:LOC116499643
uniprot id: A0A6J3E9H2
names: Similarity
names: Subunit
messages: Belongs to the avian keratin family.
messages: The avian keratins (F-ker, S-ker, C-ker and B-ker) are a complex mixture of very similar polypeptides.

219594:MAML1
gene id: 219594:MAML1
uniprot id: A0A6J3DTC6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mastermind family.
messages: Nucleus speckle

219594:LOC116498424
gene id: 219594:LOC116498424
uniprot id: A0A6J3E615
uniprot id: A0A6J3E902
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Arf family.
messages: Endosome membrane
messages: Late endosome membrane
messages: Lysosome membrane

219594:OSBPL11
gene id: 219594:OSBPL11
uniprot id: A0A6J3D3J7
names: Similarity
messages: Belongs to the OSBP family.

219594:C17H22orf39
gene id: 219594:C17H22orf39
uniprot id: A0A6J3DZC3
names: Similarity
messages: Belongs to the UPF0545 family.

219594:P4HA2
gene id: 219594:P4HA2
uniprot id: A0A6J3DN80
uniprot id: A0A6J3DN85
uniprot id: A0A6J3DTE0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P4HA family.
messages: Catalyzes the post-translational formation of 4-hydroxyproline in -Xaa-Pro-Gly- sequences in collagens and other proteins.
messages: Endoplasmic reticulum lumen

219594:LOC116493733
gene id: 219594:LOC116493733
uniprot id: A0A6J3DME0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

219594:PTPRS
gene id: 219594:PTPRS
uniprot id: A0A6J3E6Z3
uniprot id: A0A6J3E700
uniprot id: A0A6J3E703
uniprot id: A0A6J3E707
uniprot id: A0A6J3E8H8
uniprot id: A0A6J3E8I2
uniprot id: A0A6J3EBI9
uniprot id: A0A6J3EBJ3
uniprot id: A0A6J3EBK3
uniprot id: A0A6J3EC18
uniprot id: A0A6J3EC23
uniprot id: A0A6J3EC27
uniprot id: A0A6J3EDQ1
uniprot id: A0A6J3EDQ6
uniprot id: A0A6J3EDR1
uniprot id: A0A6J3EDR6
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Receptor class 2A subfamily.

219594:SDHC
gene id: 219594:SDHC
uniprot id: A0A6J3EFX8
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Component of complex II composed of four subunits: the flavoprotein (FP) SDHA, iron-sulfur protein (IP) SDHB, and a cytochrome b560 composed of SDHC and SDHD.
messages: Membrane
messages: Membrane-anchoring subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).

219594:GKAP1
gene id: 219594:GKAP1
uniprot id: A0A6J3EDU6
names: Similarity
messages: Belongs to the GKAP1 family.

219594:CCT2
gene id: 219594:CCT2
uniprot id: A0A6J3E8M2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TCP-1 chaperonin family.
messages: Cytoplasm

219594:CAPZA3
gene id: 219594:CAPZA3
uniprot id: A0A6J3CR17
names: Function
names: Similarity
names: Subunit
messages: Belongs to the F-actin-capping protein alpha subunit family.
messages: F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.
messages: Heterodimer of an alpha and a beta subunit.

219594:B3GNT4
gene id: 219594:B3GNT4
uniprot id: A0A6J3DWA6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane

219594:LOC116489330
gene id: 219594:LOC116489330
uniprot id: A0A6J3D1H6
names: Similarity
messages: Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.

219594:NRN1L
gene id: 219594:NRN1L
uniprot id: A0A6J3DP33
names: Similarity
messages: Belongs to the neuritin family.

219594:RPS27A
gene id: 219594:RPS27A
uniprot id: A0A6J3CVH7
names: Similarity
messages: In the C-terminal section; belongs to the eukaryotic ribosomal protein eS31 family.
messages: In the N-terminal section; belongs to the ubiquitin family.

219594:PYGL
gene id: 219594:PYGL
uniprot id: A0A6J3D6A6
names: Function
names: Similarity
messages: Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis.
messages: Belongs to the glycogen phosphorylase family.

219594:BRCA1
gene id: 219594:BRCA1
uniprot id: A0A6J3E511
uniprot id: A0A6J3E6F2
uniprot id: A0A6J3E9F4
names: Subcellular Location Annotation
messages: Chromosome
messages: Cytoplasm
messages: Nucleus

219594:LOC116498872
gene id: 219594:LOC116498872
uniprot id: A0A6J3E7X3
names: Similarity
messages: Belongs to the peptidase A1 family.

219594:LOC116501118
gene id: 219594:LOC116501118
uniprot id: A0A6J3EFB5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily.
messages: Membrane

219594:GALNT12
gene id: 219594:GALNT12
uniprot id: A0A6J3CP46
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
messages: Golgi apparatus membrane
messages: Membrane

219594:SMC6
gene id: 219594:SMC6
uniprot id: A0A6J3CSP6
names: Subcellular Location Annotation
messages: Chromosome

219594:HS3ST4
gene id: 219594:HS3ST4
uniprot id: A0A6J3DWB9
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

219594:VEZT
gene id: 219594:VEZT
uniprot id: A0A6J3CEB4
uniprot id: A0A6J3CGE8
uniprot id: A0A6J3CGN8
uniprot id: A0A6J3CJS1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vezatin family.
messages: Cell membrane
messages: Membrane
messages: Nucleus
messages: adherens junction

219594:LOC116501316
gene id: 219594:LOC116501316
uniprot id: A0A6J3EG68
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

219594:ALDH2
gene id: 219594:ALDH2
uniprot id: A0A6J3DUR5
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

219594:MEGF6
gene id: 219594:MEGF6
uniprot id: A0A6J3E651
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:PSMG1
gene id: 219594:PSMG1
uniprot id: A0A6J3E4J8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PSMG1 family.
messages: Chaperone protein which promotes assembly of the 20S proteasome as part of a heterodimer with psmg2.
messages: Cytoplasm
messages: Forms a heterodimer with psmg2.

219594:ANO6
gene id: 219594:ANO6
uniprot id: A0A6J3EHH7
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anoctamin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

219594:INTS10
gene id: 219594:INTS10
uniprot id: A0A6J3CVD3
uniprot id: A0A6J3CVS3
uniprot id: A0A6J3CY40
uniprot id: A0A6J3CZ62
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Integrator subunit 10 family.
messages: Nucleus

219594:CS
gene id: 219594:CS
uniprot id: A0A6J3EFQ8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the citrate synthase family.
messages: Homodimer.
messages: Mitochondrion matrix

219594:MKNK1
gene id: 219594:MKNK1
uniprot id: A0A6J3DA98
names: Similarity
messages: Belongs to the protein kinase superfamily.

219594:GDPD4
gene id: 219594:GDPD4
uniprot id: A0A6J3E2Z8
names: Similarity
messages: Belongs to the glycerophosphoryl diester phosphodiesterase family.

219594:TASOR2
gene id: 219594:TASOR2
uniprot id: A0A6J3EII0
names: Similarity
messages: Belongs to the TASOR family.

219594:SNCG
gene id: 219594:SNCG
uniprot id: A0A6J3DBQ4
names: Similarity
names: Subunit
messages: Belongs to the synuclein family.
messages: May be a centrosome-associated protein. Interacts with MYOC; affects its secretion and its aggregation.

219594:PRPF18
gene id: 219594:PRPF18
uniprot id: A0A6J3EN07
uniprot id: A0A6J3EPE5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRP18 family.
messages: Nucleus speckle

219594:CC2D1B
gene id: 219594:CC2D1B
uniprot id: A0A6J3DE67
names: Similarity
messages: Belongs to the CC2D1 family.

219594:CAMSAP1
gene id: 219594:CAMSAP1
uniprot id: A0A6J3E284
uniprot id: A0A6J3E3C7
names: Domain
names: Similarity
messages: Belongs to the CAMSAP1 family.
messages: The CKK domain binds microtubules.

219594:NDEL1
gene id: 219594:NDEL1
uniprot id: A0A6J3DXS0
uniprot id: A0A6J3E029
uniprot id: A0A6J3E205
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nudE family.
messages: centrosome
messages: spindle

219594:LOC116501277
gene id: 219594:LOC116501277
uniprot id: A0A6J3EMR8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:LOC116499726
gene id: 219594:LOC116499726
uniprot id: A0A6J3E9H2
names: Similarity
names: Subunit
messages: Belongs to the avian keratin family.
messages: The avian keratins (F-ker, S-ker, C-ker and B-ker) are a complex mixture of very similar polypeptides.

219594:OLFM4
gene id: 219594:OLFM4
uniprot id: A0A6J3EHT3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:PIGU
gene id: 219594:PIGU
uniprot id: A0A6J3DWT9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PIGU family.
messages: Endoplasmic reticulum membrane
messages: Membrane

219594:COPS8
gene id: 219594:COPS8
uniprot id: A0A6J3D6Z2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CSN8 family.
messages: Cytoplasm
messages: Nucleus

219594:COQ4
gene id: 219594:COQ4
uniprot id: A0A6J3E2H9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the COQ4 family.
messages: Component of a multi-subunit COQ enzyme complex, composed of at least COQ3, COQ4, COQ5, COQ6, COQ7 and COQ9.
messages: Component of the coenzyme Q biosynthetic pathway. May play a role in organizing a multi-subunit COQ enzyme complex required for coenzyme Q biosynthesis. Required for steady-state levels of other COQ polypeptides.
messages: Mitochondrion inner membrane

219594:AMBP
gene id: 219594:AMBP
uniprot id: A0A6J3E177
names: Similarity
names: Subcellular Location Annotation
messages: In the N-terminal section; belongs to the calycin superfamily. Lipocalin family.
messages: Secreted

219594:HCN1
gene id: 219594:HCN1
uniprot id: A0A6J3EK52
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the potassium channel HCN family.
messages: Cell membrane
messages: Membrane

219594:FUT7
gene id: 219594:FUT7
uniprot id: A0A6J3E350
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 10 family.
messages: Golgi stack membrane

219594:SPCS2
gene id: 219594:SPCS2
uniprot id: A0A6J3EP40
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPCS2 family.
messages: Component of the signal peptidase complex (SPC) which catalyzes the cleavage of N-terminal signal sequences from nascent proteins as they are translocated into the lumen of the endoplasmic reticulum. Enhances the enzymatic activity of SPC and facilitates the interactions between different components of the translocation site.
messages: Endoplasmic reticulum membrane
messages: Membrane

219594:KIF3C
gene id: 219594:KIF3C
uniprot id: A0A6J3CLS6
uniprot id: A0A6J3CNH1
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

219594:F3
gene id: 219594:F3
uniprot id: A0A6J3DDH6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tissue factor family.
messages: Initiates blood coagulation by forming a complex with circulating factor VII or VIIa. The [TF:VIIa] complex activates factors IX or X by specific limited proteolysis. TF plays a role in normal hemostasis by initiating the cell-surface assembly and propagation of the coagulation protease cascade.
messages: Interacts with HSPE; the interaction, inhibited by heparin, promotes the generation of activated factor X and activates coagulation in the presence of activated factor VII.

219594:VEGFD
gene id: 219594:VEGFD
uniprot id: A0A6J3EIV8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PDGF/VEGF growth factor family.
messages: Secreted

219594:LOC116487304
gene id: 219594:LOC116487304
uniprot id: A0A6J3CLU2
names: Similarity
messages: Belongs to the AHA1 family.

219594:LOC116486267
gene id: 219594:LOC116486267
uniprot id: A0A6J3CGX0
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

219594:EIF4EBP1
gene id: 219594:EIF4EBP1
uniprot id: A0A6J3EDL0
names: Similarity
messages: Belongs to the eIF4E-binding protein family.

219594:NOC2L
gene id: 219594:NOC2L
uniprot id: A0A6J3E5T3
names: Similarity
messages: Belongs to the NOC2 family.

219594:LOC116502210
gene id: 219594:LOC116502210
uniprot id: A0A6J3EJH0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

219594:TJP2
gene id: 219594:TJP2
uniprot id: A0A6J3EDU3
uniprot id: A0A6J3EJ61
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: tight junction

219594:XPO1
gene id: 219594:XPO1
uniprot id: A0A6J3CN38
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exportin family.
messages: Cytoplasm

219594:LOC116500391
gene id: 219594:LOC116500391
uniprot id: A0A6J3EGT5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alpha/beta interferon family.
messages: Has antiviral activities.
messages: Secreted

219594:SGTA
gene id: 219594:SGTA
uniprot id: A0A6J3E7N4
uniprot id: A0A6J3ECQ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SGT family.
messages: Cytoplasm

219594:FGF12
gene id: 219594:FGF12
uniprot id: A0A6J3DCB0
uniprot id: A0A6J3DF03
uniprot id: A0A6J3DHU0
uniprot id: A0A6J3DIE3
names: Similarity
messages: Belongs to the heparin-binding growth factors family.

219594:RNF145
gene id: 219594:RNF145
uniprot id: A0A6J3DSA9
names: Subcellular Location Annotation
messages: Membrane

219594:PJVK
gene id: 219594:PJVK
uniprot id: A0A6J3DB70
names: Similarity
messages: Belongs to the gasdermin family.

219594:SMS
gene id: 219594:SMS
uniprot id: A0A6J3D0S5
names: Similarity
messages: Belongs to the spermidine/spermine synthase family.

219594:PAN2
gene id: 219594:PAN2
uniprot id: A0A6J3EHE9
names: Activity Regulation
names: Caution
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase C19 family. PAN2 subfamily.
messages: Binds 2 metal cations per subunit in the catalytic exonuclease domain.
messages: Catalytic subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in general and miRNA-mediated mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein (PABP). PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent mRNA decaping and subsequent 5'-3' exonucleolytic degradation by XRN1.
messages: Contains a pseudo-UCH domain. This ubiquitin C-terminal hydrolase (UCH)-like or ubiquitin specific protease (USP)-like domain is predicted to be catalytically inactive because it lacks the active site catalytic triad characteristic of thiol proteases, with residues at the equivalent structural positions that are incompatible with catalysis, and it cannot bind ubiquitin. It functions as a structural scaffold for intra- and intermolecular interactions in the complex.
messages: Forms a heterotrimer with an asymmetric homodimer of the regulatory subunit PAN3 to form the poly(A)-nuclease (PAN) deadenylation complex.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus
messages: P-body
messages: Positively regulated by the regulatory subunit PAN3.
messages: The linker, or PAN3 interaction domain (PID), between the WD40 repeats and the pseudo-UCH domain mediates interaction with PAN3.

219594:ADAT2
gene id: 219594:ADAT2
uniprot id: A0A6J3CNB6
names: Function
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family. ADAT2 subfamily.
messages: Probably participates in deamination of adenosine-34 to inosine in many tRNAs.

219594:TCEA3
gene id: 219594:TCEA3
uniprot id: A0A6J3E3P1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TFS-II family.
messages: Necessary for efficient RNA polymerase II transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by S-II allows the resumption of elongation from the new 3'-terminus.
messages: Nucleus

219594:LOC116502180
gene id: 219594:LOC116502180
uniprot id: A0A6J3EJB1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

219594:CHSY3
gene id: 219594:CHSY3
uniprot id: A0A6J3EGE3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chondroitin N-acetylgalactosaminyltransferase family.
messages: Golgi stack membrane
messages: Membrane

219594:LOC116494672
gene id: 219594:LOC116494672
uniprot id: A0A6J3DPF7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

219594:TCTEX1D4
gene id: 219594:TCTEX1D4
uniprot id: A0A6J3DBB8
names: Similarity
messages: Belongs to the dynein light chain Tctex-type family.

219594:BICD1
gene id: 219594:BICD1
uniprot id: A0A6J3EBU9
uniprot id: A0A6J3EC38
uniprot id: A0A6J3EDA6
uniprot id: A0A6J3EDB1
uniprot id: A0A6J3EGM3
uniprot id: A0A6J3EGN3
uniprot id: A0A6J3EGX8
uniprot id: A0A6J3EGY5
uniprot id: A0A6J3EH12
uniprot id: A0A6J3EH43
uniprot id: A0A6J3EIJ0
names: Similarity
messages: Belongs to the BicD family.

219594:SPR
gene id: 219594:SPR
uniprot id: A0A6J3CX33
names: Similarity
messages: Belongs to the sepiapterin reductase family.

219594:SYPL1
gene id: 219594:SYPL1
uniprot id: A0A6J3CFC0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptophysin/synaptobrevin family.
messages: Membrane

219594:HDX
gene id: 219594:HDX
uniprot id: A0A6J3DKS5
uniprot id: A0A6J3DN83
uniprot id: A0A6J3DQ13
names: Subcellular Location Annotation
messages: Nucleus

219594:SEC31A
gene id: 219594:SEC31A
uniprot id: A0A6J3CTE8
uniprot id: A0A6J3CVR2
uniprot id: A0A6J3CVR6
uniprot id: A0A6J3CW67
uniprot id: A0A6J3CYI1
uniprot id: A0A6J3CZK0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat SEC31 family.
messages: Endoplasmic reticulum membrane

219594:CMTM8
gene id: 219594:CMTM8
uniprot id: A0A6J3CET0
names: Subcellular Location Annotation
messages: Membrane

219594:LOC116486736
gene id: 219594:LOC116486736
uniprot id: A0A6J3CNY1
names: Function
names: Similarity
messages: Belongs to the PET191 family.
messages: Involved in an early step of the mitochondrial complex IV assembly process.

219594:PNLDC1
gene id: 219594:PNLDC1
uniprot id: A0A6J3CR54
uniprot id: A0A6J3CRU1
names: Similarity
messages: Belongs to the CAF1 family.

219594:GALNT9
gene id: 219594:GALNT9
uniprot id: A0A6J3DYF0
uniprot id: A0A6J3DZI3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
messages: Golgi apparatus membrane
messages: Membrane

219594:LOC116498566
gene id: 219594:LOC116498566
uniprot id: A0A6J3E9K8
names: Similarity
names: Subunit
messages: Belongs to the avian keratin family.
messages: The avian keratins (F-ker, S-ker, C-ker and B-ker) are a complex mixture of very similar polypeptides.

219594:GLP2R
gene id: 219594:GLP2R
uniprot id: A0A6J3DY94
names: Subcellular Location Annotation
messages: Membrane

219594:SIX2
gene id: 219594:SIX2
uniprot id: A0A6J3CVH1
names: Subcellular Location Annotation
messages: Nucleus

219594:AP1M1
gene id: 219594:AP1M1
uniprot id: A0A6J3EBP7
names: Similarity
messages: Belongs to the adaptor complexes medium subunit family.

219594:TAP2
gene id: 219594:TAP2
uniprot id: A0A6J3EBL5
names: Subcellular Location Annotation
messages: Membrane

219594:RTCB
gene id: 219594:RTCB
uniprot id: A0A6J3E7U2
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RtcB family.
messages: Binds 2 manganese ions per subunit.
messages: Catalytic component of the tRNA-splicing ligase complex.
messages: Catalytic subunit of the tRNA-splicing ligase complex that acts by directly joining spliced tRNA halves to mature-sized tRNAs by incorporating the precursor-derived splice junction phosphate into the mature tRNA as a canonical 3',5'-phosphodiester. May act as an RNA ligase with broad substrate specificity, and may function toward other RNAs.
messages: Cytoplasm
messages: Ligation probably proceeds through 3 nucleotidyl transfer steps, with 2',3'-cyclic phosphate termini being hydrolyzed to 3'-P termini in a step that precedes 3'-P activation with GMP. In the first nucleotidyl transfer step, RTCB reacts with GTP to form a covalent RTCB-histidine-GMP intermediate with release of PPi; in the second step, the GMP moiety is transferred to the RNA 3'-P; in the third step, the 5'-OH from the opposite RNA strand attacks the activated 3'-P to form a 3',5'-phosphodiester bond and release GMP.

219594:SLC25A24
gene id: 219594:SLC25A24
uniprot id: A0A6J3D9W6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane
messages: Mitochondrion inner membrane

219594:DYNC1LI1
gene id: 219594:DYNC1LI1
uniprot id: A0A6J3CEU3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes.
messages: Belongs to the dynein light intermediate chain family.
messages: Homodimer. The cytoplasmic dynein 1 complex consists of two catalytic heavy chains (HCs) and a number of non-catalytic subunits presented by intermediate chains (ICs).
messages: cytoskeleton

219594:DPY19L4
gene id: 219594:DPY19L4
uniprot id: A0A6J3CGH3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dpy-19 family.
messages: Membrane
messages: Probable C-mannosyltransferase that mediates C-mannosylation of tryptophan residues on target proteins.

219594:TM9SF2
gene id: 219594:TM9SF2
uniprot id: A0A6J3DM44
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nonaspanin (TM9SF) (TC 9.A.2) family.
messages: Membrane

219594:LOC116485365
gene id: 219594:LOC116485365
uniprot id: A0A6J3CC30
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:SLC13A5
gene id: 219594:SLC13A5
uniprot id: A0A6J3DZS3
uniprot id: A0A6J3E3Z5
uniprot id: A0A6J3E5V7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC13A/DASS transporter (TC 2.A.47) family. NADC subfamily.
messages: Membrane

219594:MMD2
gene id: 219594:MMD2
uniprot id: A0A6J3DT55
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ADIPOR family.
messages: Membrane

219594:SEMA4C
gene id: 219594:SEMA4C
uniprot id: A0A6J3E8K7
names: Caution
names: Similarity
messages: Belongs to the semaphorin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:RAB33A
gene id: 219594:RAB33A
uniprot id: A0A6J3DRX7
names: Similarity
messages: Belongs to the small GTPase superfamily. Rab family.

219594:FAM135A
gene id: 219594:FAM135A
uniprot id: A0A6J3CM56
uniprot id: A0A6J3CNX2
names: Similarity
messages: Belongs to the FAM135 family.

219594:CD6
gene id: 219594:CD6
uniprot id: A0A6J3CXQ2
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:LOC116501291
gene id: 219594:LOC116501291
uniprot id: A0A6J3ELB9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:DUSP10
gene id: 219594:DUSP10
uniprot id: A0A6J3CP11
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.

219594:CDC14B
gene id: 219594:CDC14B
uniprot id: A0A6J3ECE2
uniprot id: A0A6J3ECE6
uniprot id: A0A6J3EH80
uniprot id: A0A6J3EHH1
uniprot id: A0A6J3EHH5
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class CDC14 subfamily.

219594:SIGIRR
gene id: 219594:SIGIRR
uniprot id: A0A6J3D0B2
names: Similarity
messages: Belongs to the interleukin-1 receptor family.

219594:TSPO
gene id: 219594:TSPO
uniprot id: A0A6J3CKW8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TspO/BZRP family.
messages: Membrane

219594:VEPH1
gene id: 219594:VEPH1
uniprot id: A0A6J3DJZ0
names: Similarity
messages: Belongs to the MELT/VEPH family.

219594:LHX1
gene id: 219594:LHX1
uniprot id: A0A6J3E045
names: Subcellular Location Annotation
messages: Nucleus

219594:KIFC3
gene id: 219594:KIFC3
uniprot id: A0A6J3DR77
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

219594:NPPC
gene id: 219594:NPPC
uniprot id: A0A6J3DJS3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the natriuretic peptide family.
messages: Secreted

219594:SPCS1
gene id: 219594:SPCS1
uniprot id: A0A6J3DFW4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPCS1 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

219594:LOC116499987
gene id: 219594:LOC116499987
uniprot id: A0A6J3EFV2
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:LGMN
gene id: 219594:LGMN
uniprot id: A0A6J3CZV6
names: Similarity
messages: Belongs to the peptidase C13 family.

219594:MFF
gene id: 219594:MFF
uniprot id: A0A6J3DBK4
uniprot id: A0A6J3DE72
uniprot id: A0A6J3DFC0
uniprot id: A0A6J3DH31
uniprot id: A0A6J3DH35
uniprot id: A0A6J3DHK6
uniprot id: A0A6J3DHL1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Tango11 family.
messages: Membrane
messages: Mitochondrion outer membrane
messages: Peroxisome
messages: Plays a role in mitochondrial and peroxisomal fission. Promotes the recruitment and association of the fission mediator dynamin-related protein 1 (DNM1L) to the mitochondrial surface.

219594:CTSE
gene id: 219594:CTSE
uniprot id: A0A6J3EB86
names: Similarity
messages: Belongs to the peptidase A1 family.

219594:HNRNPAB
gene id: 219594:HNRNPAB
uniprot id: A0A6J3DR12
uniprot id: A0A6J3DT16
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

219594:DPYS
gene id: 219594:DPYS
uniprot id: A0A6J3CNA2
names: PTM
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Hydantoinase/dihydropyrimidinase family.
messages: Carbamylation allows a single lysine to coordinate two divalent metal cations.

219594:AP5M1
gene id: 219594:AP5M1
uniprot id: A0A6J3CZ37
uniprot id: A0A6J3D1N3
names: Subcellular Location Annotation
names: Subunit
messages: Endosome membrane
messages: Late endosome membrane
messages: Lysosome membrane
messages: Membrane
messages: Probably part of the adaptor protein complex 5 (AP-5) a tetramer composed of AP5B1, AP5M1, AP5S1 and AP5Z1.

219594:COPZ2
gene id: 219594:COPZ2
uniprot id: A0A6J3E423
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adaptor complexes small subunit family.
messages: COPI-coated vesicle membrane
messages: Cytoplasm
messages: Golgi apparatus membrane
messages: Oligomeric complex that consists of at least the alpha, beta, beta', gamma, delta, epsilon and zeta subunits.
messages: The zeta subunit may be involved in regulating the coat assembly and, hence, the rate of biosynthetic protein transport due to its association-dissociation properties with the coatomer complex.

219594:MRPS14
gene id: 219594:MRPS14
uniprot id: A0A6J3DF77
names: Similarity
messages: Belongs to the universal ribosomal protein uS14 family.

219594:SMG7
gene id: 219594:SMG7
uniprot id: A0A6J3D988
uniprot id: A0A6J3D992
uniprot id: A0A6J3DBY5
uniprot id: A0A6J3DCX0
uniprot id: A0A6J3DEZ5
uniprot id: A0A6J3DF49
names: Function
names: Subcellular Location Annotation
messages: Nucleus
messages: Plays a role in nonsense-mediated mRNA decay.

219594:PFN2
gene id: 219594:PFN2
uniprot id: A0A6J3DCP4
uniprot id: A0A6J3DI90
names: Similarity
messages: Belongs to the profilin family.

219594:SLC10A1
gene id: 219594:SLC10A1
uniprot id: A0A6J3D0C1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bile acid:sodium symporter (BASS) (TC 2.A.28) family.
messages: Membrane

219594:UBE2F
gene id: 219594:UBE2F
uniprot id: A0A6J3D5P4
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

219594:SERINC2
gene id: 219594:SERINC2
uniprot id: A0A6J3E7W0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TDE1 family.
messages: Membrane

219594:LOC116499978
gene id: 219594:LOC116499978
uniprot id: A0A6J3EFQ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

219594:SCMH1
gene id: 219594:SCMH1
uniprot id: A0A6J3E507
uniprot id: A0A6J3E8J4
uniprot id: A0A6J3E8J9
uniprot id: A0A6J3EA07
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SCM family.
messages: Nucleus

219594:LGI1
gene id: 219594:LGI1
uniprot id: A0A6J3D9B0
uniprot id: A0A6J3DC29
uniprot id: A0A6J3DCI8
names: Subcellular Location Annotation
messages: Secreted

219594:TULP4
gene id: 219594:TULP4
uniprot id: A0A6J3CSA1
names: Similarity
messages: Belongs to the TUB family.

219594:GPR132
gene id: 219594:GPR132
uniprot id: A0A6J3CZZ9
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

219594:LOC116486794
gene id: 219594:LOC116486794
uniprot id: A0A6J3CM85
names: Similarity
names: Subunit
messages: Belongs to the avian keratin family.
messages: The avian keratins (F-ker, S-ker, C-ker and B-ker) are a complex mixture of very similar polypeptides.

219594:FAP
gene id: 219594:FAP
uniprot id: A0A6J3DA49
names: Subcellular Location Annotation
messages: Cell membrane
messages: invadopodium membrane
messages: lamellipodium membrane

219594:GLRA1
gene id: 219594:GLRA1
uniprot id: A0A6J3DMV2
uniprot id: A0A6J3DS75
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family. Glycine receptor (TC 1.A.9.3) subfamily. GLRA1 sub-subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Perikaryon
messages: Postsynaptic cell membrane
messages: Synapse
messages: Synaptic cell membrane
messages: dendrite

219594:LOC116486553
gene id: 219594:LOC116486553
uniprot id: A0A6J3CN19
names: Function
names: Similarity
messages: Belongs to the alpha-carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

219594:GRM3
gene id: 219594:GRM3
uniprot id: A0A6J3D145
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 3 family.
messages: Cell membrane
messages: G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. Signaling inhibits adenylate cyclase activity.
messages: Interacts with TAMALIN.
messages: Membrane

219594:RPTOR
gene id: 219594:RPTOR
uniprot id: A0A6J3DVH7
uniprot id: A0A6J3DZN4
names: Similarity
messages: Belongs to the WD repeat RAPTOR family.

219594:TNKS2
gene id: 219594:TNKS2
uniprot id: A0A6J3DBT1
names: Similarity
messages: Belongs to the ARTD/PARP family.

219594:GSX2
gene id: 219594:GSX2
uniprot id: A0A6J3CUV5
names: Subcellular Location Annotation
messages: Nucleus

219594:PARD6B
gene id: 219594:PARD6B
uniprot id: A0A6J3DY18
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAR6 family.
messages: Cytoplasm
messages: tight junction

219594:EXT1
gene id: 219594:EXT1
uniprot id: A0A6J3CLC1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 47 family.
messages: Endoplasmic reticulum membrane

219594:AKIRIN2
gene id: 219594:AKIRIN2
uniprot id: A0A6J3CU98
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the akirin family.
messages: Nucleus

219594:FAM20A
gene id: 219594:FAM20A
uniprot id: A0A6J3E283
names: Similarity
messages: Belongs to the FAM20 family.

219594:VAT1
gene id: 219594:VAT1
uniprot id: A0A6J3E8T5
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily.

219594:FOXJ1
gene id: 219594:FOXJ1
uniprot id: A0A6J3E1J1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FOXJ1 family.
messages: Nucleus

219594:KDM5B
gene id: 219594:KDM5B
uniprot id: A0A6J3E770
uniprot id: A0A6J3ECD8
names: Similarity
messages: Belongs to the JARID1 histone demethylase family.

219594:DUSP5
gene id: 219594:DUSP5
uniprot id: A0A6J3DAC5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.
messages: Nucleus

219594:OGT
gene id: 219594:OGT
uniprot id: A0A6J3DLW5
uniprot id: A0A6J3DR59
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 41 family. O-GlcNAc transferase subfamily.
messages: Cell projection
messages: Mitochondrion membrane

219594:CCT7
gene id: 219594:CCT7
uniprot id: A0A6J3D0B5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TCP-1 chaperonin family.
messages: Cytoplasm
messages: Heterooligomeric complex of about 850 to 900 kDa that forms two stacked rings, 12 to 16 nm in diameter.
messages: Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. Known to play a role, in vitro, in the folding of actin and tubulin.

219594:REEP4
gene id: 219594:REEP4
uniprot id: A0A6J3ED85
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DP1 family.
messages: Membrane

219594:MEOX1
gene id: 219594:MEOX1
uniprot id: A0A6J3E4P2
names: Subcellular Location Annotation
messages: Nucleus

219594:LOC116491096
gene id: 219594:LOC116491096
uniprot id: A0A6J3DAV6
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Chromosome
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers.
messages: Variant histone H2A which replaces conventional H2A in a subset of nucleosomes.

219594:TIMP3
gene id: 219594:TIMP3
uniprot id: A0A6J3EQ46
names: Similarity
messages: Belongs to the protease inhibitor I35 (TIMP) family.

219594:PACC1
gene id: 219594:PACC1
uniprot id: A0A6J3CNI4
uniprot id: A0A6J3CQR3
uniprot id: A0A6J3CRU3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the proton-activated chloride channel family.
messages: Cell membrane
messages: Membrane

219594:FGF14
gene id: 219594:FGF14
uniprot id: A0A6J3DUZ0
uniprot id: A0A6J3DX85
uniprot id: A0A6J3DXZ7
names: Similarity
messages: Belongs to the heparin-binding growth factors family.

219594:HNRNPH1
gene id: 219594:HNRNPH1
uniprot id: A0A6J3DMC0
uniprot id: A0A6J3DPN2
uniprot id: A0A6J3DRN0
uniprot id: A0A6J3DRN7
uniprot id: A0A6J3DSG7
uniprot id: A0A6J3DTK5
uniprot id: A0A6J3DTL1
names: Subcellular Location Annotation
messages: nucleoplasm

219594:LOC116489567
gene id: 219594:LOC116489567
uniprot id: A0A6J3D3V1
names: Domain
names: Subcellular Location Annotation
messages: The N-terminal C2 domain associates with lipid membranes upon calcium binding.
messages: cytosol

219594:LMLN
gene id: 219594:LMLN
uniprot id: A0A6J3D6M4
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M8 family.
messages: Binds 1 zinc ion per subunit.

219594:SCNN1B
gene id: 219594:SCNN1B
uniprot id: A0A6J3DSG9
names: Subcellular Location Annotation
messages: Membrane

219594:LOC116490398
gene id: 219594:LOC116490398
uniprot id: A0A6J3D4M6
names: Similarity
messages: Belongs to the serpin family.

219594:TICAM1
gene id: 219594:TICAM1
uniprot id: A0A6J3EBL7
names: Domain
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Homodimer. Found in a multi-helicase-TICAM1 complex at least composed of DHX36, DDX1, DDX21 and TICAM1.
messages: Involved in innate immunity against invading pathogens. Adapter used by TLR3, TLR4 (through TICAM2) and TLR5 to mediate NF-kappa-B and interferon-regulatory factor (IRF) activation, and to induce apoptosis. Ligand binding to these receptors results in TRIF recruitment through its TIR domain. Distinct protein-interaction motifs allow recruitment of the effector proteins TBK1, TRAF6 and RIPK1, which in turn, lead to the activation of transcription factors IRF3 and IRF7, NF-kappa-B and FADD respectively. Phosphorylation by TBK1 on the pLxIS motif leads to recruitment and subsequent activation of the transcription factor IRF3 to induce expression of type I interferon and exert a potent immunity against invading pathogens. Component of a multi-helicase-TICAM1 complex that acts as a cytoplasmic sensor of viral double-stranded RNA (dsRNA) and plays a role in the activation of a cascade of antiviral responses including the induction of pro-inflammatory cytokines.
messages: Mitochondrion
messages: The N-terminal region is essential for activation of the IFNB promoter activity.
messages: autophagosome
messages: cytosol

219594:FLT3
gene id: 219594:FLT3
uniprot id: A0A6J3EIQ8
names: Subcellular Location Annotation
messages: Membrane

219594:SUSD3
gene id: 219594:SUSD3
uniprot id: A0A6J3DLG9
uniprot id: A0A6J3DLZ1
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:TCN2
gene id: 219594:TCN2
uniprot id: A0A6J3DZ00
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic cobalamin transport proteins family.
messages: Secreted

219594:LOC116501896
gene id: 219594:LOC116501896
uniprot id: A0A6J3EPX0
names: Similarity
messages: Belongs to the CRISP family.

219594:INHA
gene id: 219594:INHA
uniprot id: A0A6J3D899
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TGF-beta family.
messages: Dimeric, linked by one or more disulfide bonds. Inhibin A is a dimer of alpha and beta-A. Inhibin B is a dimer of alpha and beta-B.
messages: Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition.
messages: Secreted

219594:AMIGO1
gene id: 219594:AMIGO1
uniprot id: A0A6J3ECL0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the immunoglobulin superfamily. AMIGO family.
messages: Membrane

219594:SLC39A14
gene id: 219594:SLC39A14
uniprot id: A0A6J3E887
names: Subcellular Location Annotation
messages: Membrane

219594:LOC116500190
gene id: 219594:LOC116500190
uniprot id: A0A6J3EGE5
uniprot id: A0A6J3EI03
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: Nematocyst
messages: Target cell membrane

219594:ADCY1
gene id: 219594:ADCY1
uniprot id: A0A6J3CJB0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
messages: Binds 2 magnesium ions per subunit. Is also active with manganese (in vitro).
messages: Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.
messages: Membrane

219594:CELF2
gene id: 219594:CELF2
uniprot id: A0A6J3EIR1
uniprot id: A0A6J3EIR4
uniprot id: A0A6J3EK19
uniprot id: A0A6J3ENX9
uniprot id: A0A6J3ENZ9
uniprot id: A0A6J3EQF1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CELF/BRUNOL family.
messages: Cytoplasm
messages: Nucleus

219594:CDH12
gene id: 219594:CDH12
uniprot id: A0A6J3CKC2
names: Function
names: Subcellular Location Annotation
messages: Cadherins are calcium-dependent cell adhesion proteins.
messages: Cell membrane

219594:GPR37
gene id: 219594:GPR37
uniprot id: A0A6J3ERP5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

219594:DNMT3A
gene id: 219594:DNMT3A
uniprot id: A0A6J3CPQ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.
messages: Nucleus

219594:GLDN
gene id: 219594:GLDN
uniprot id: A0A6J3DI85
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:TBX19
gene id: 219594:TBX19
uniprot id: A0A6J3EQF6
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

219594:BLCAP
gene id: 219594:BLCAP
uniprot id: A0A6J3DZ46
names: Similarity
messages: Belongs to the BLCAP family.

219594:ELOF1
gene id: 219594:ELOF1
uniprot id: A0A6J3EFU8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELOF1 family.
messages: Nucleus
messages: Transcription elongation factor implicated in the maintenance of proper chromatin structure in actively transcribed regions.

219594:LOC116499729
gene id: 219594:LOC116499729
uniprot id: A0A6J3E9H2
names: Similarity
names: Subunit
messages: Belongs to the avian keratin family.
messages: The avian keratins (F-ker, S-ker, C-ker and B-ker) are a complex mixture of very similar polypeptides.

219594:ZFYVE26
gene id: 219594:ZFYVE26
uniprot id: A0A6J3CXI8
uniprot id: A0A6J3CZW8
uniprot id: A0A6J3D3I7
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Interacts with AP5Z1, AP5B1, AP5S1 and SPG11. Interacts with TTC19 and KIF13A.
messages: Midbody
messages: Phosphatidylinositol 3-phosphate-binding protein required for the abcission step in cytokinesis: recruited to the midbody during cytokinesis and acts as a regulator of abcission. May also be required for efficient homologous recombination DNA double-strand break repair.

219594:PRRX2
gene id: 219594:PRRX2
uniprot id: A0A6J3DXR8
uniprot id: A0A6J3E2S3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the paired homeobox family.
messages: Nucleus

219594:CTNND1
gene id: 219594:CTNND1
uniprot id: A0A6J3D2K4
uniprot id: A0A6J3D2T5
uniprot id: A0A6J3D544
uniprot id: A0A6J3D620
names: Similarity
messages: Belongs to the beta-catenin family.

219594:PPP2R2C
gene id: 219594:PPP2R2C
uniprot id: A0A6J3CS54
uniprot id: A0A6J3CUX5
uniprot id: A0A6J3CX74
uniprot id: A0A6J3CYB6
names: Similarity
messages: Belongs to the phosphatase 2A regulatory subunit B family.

219594:BRIX1
gene id: 219594:BRIX1
uniprot id: A0A6J3EII2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BRX1 family.
messages: Required for biogenesis of the 60S ribosomal subunit.
messages: nucleolus

219594:C6
gene id: 219594:C6
uniprot id: A0A6J3EF43
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complement C6/C7/C8/C9 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

219594:SNRNP200
gene id: 219594:SNRNP200
uniprot id: A0A6J3ED76
names: Similarity
messages: Belongs to the helicase family. SKI2 subfamily.

219594:PRL
gene id: 219594:PRL
uniprot id: A0A6J3CHR7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the somatotropin/prolactin family.
messages: Secreted

219594:ITGA7
gene id: 219594:ITGA7
uniprot id: A0A6J3EAK5
uniprot id: A0A6J3EBY1
uniprot id: A0A6J3EH94
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin alpha chain family.
messages: Membrane

219594:AKAP5
gene id: 219594:AKAP5
uniprot id: A0A6J3D2I2
names: Subcellular Location Annotation
messages: Membrane

219594:CHRDL2
gene id: 219594:CHRDL2
uniprot id: A0A6J3EIU9
names: Subcellular Location Annotation
messages: Secreted

219594:DPT
gene id: 219594:DPT
uniprot id: A0A6J3CPX3
names: Similarity
messages: Belongs to the dermatopontin family.

219594:TAF11
gene id: 219594:TAF11
uniprot id: A0A6J3E7Y4
names: Similarity
messages: Belongs to the TAF11 family.

219594:PSMD5
gene id: 219594:PSMD5
uniprot id: A0A6J3E3X8
names: Similarity
messages: Belongs to the proteasome subunit S5B/HSM3 family.

219594:VPS37B
gene id: 219594:VPS37B
uniprot id: A0A6J3DZN0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VPS37 family.
messages: Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies. May be involved in cell growth and differentiation.
messages: Endosome membrane
messages: Late endosome membrane

219594:DECR2
gene id: 219594:DECR2
uniprot id: A0A6J3DRM0
uniprot id: A0A6J3DVF3
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. 2,4-dienoyl-CoA reductase subfamily.
messages: Monomer, dimer and oligomer.

219594:OSBPL3
gene id: 219594:OSBPL3
uniprot id: A0A6J3CFS5
uniprot id: A0A6J3CHE0
uniprot id: A0A6J3CKB9
uniprot id: A0A6J3CKC5
uniprot id: A0A6J3CM16
names: Similarity
messages: Belongs to the OSBP family.

219594:LOC116501909
gene id: 219594:LOC116501909
uniprot id: A0A6J3EIA9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

219594:MAP2K3
gene id: 219594:MAP2K3
uniprot id: A0A6J3DR21
uniprot id: A0A6J3DVF1
names: Similarity
messages: Belongs to the protein kinase superfamily.

219594:ACER1
gene id: 219594:ACER1
uniprot id: A0A6J3E9L2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alkaline ceramidase family.
messages: Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid.
messages: Membrane

219594:TMC1
gene id: 219594:TMC1
uniprot id: A0A6J3EJM5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMC family.
messages: Membrane

219594:FSTL5
gene id: 219594:FSTL5
uniprot id: A0A6J3CWI2
uniprot id: A0A6J3CYR2
names: Subcellular Location Annotation
messages: Secreted

219594:MTMR9
gene id: 219594:MTMR9
uniprot id: A0A6J3CP30
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily.

219594:CCSER1
gene id: 219594:CCSER1
uniprot id: A0A6J3D1B7
names: Similarity
messages: Belongs to the CCSER family.

219594:YWHAZ
gene id: 219594:YWHAZ
uniprot id: A0A6J3CL35
names: Similarity
messages: Belongs to the 14-3-3 family.

219594:SRP19
gene id: 219594:SRP19
uniprot id: A0A6J3EJU1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SRP19 family.
messages: Cytoplasm

219594:ARID1B
gene id: 219594:ARID1B
uniprot id: A0A6J3CRD7
uniprot id: A0A6J3CTP1
uniprot id: A0A6J3CXJ5
names: Subcellular Location Annotation
messages: Nucleus

219594:RBFOX3
gene id: 219594:RBFOX3
uniprot id: A0A6J3DVZ2
uniprot id: A0A6J3DXU7
uniprot id: A0A6J3DXV2
uniprot id: A0A6J3E059
uniprot id: A0A6J3E0Z0
uniprot id: A0A6J3E240
names: Function
names: Subcellular Location Annotation
messages: Nucleus
messages: RNA-binding protein that regulates alternative splicing events.

219594:LOC116500127
gene id: 219594:LOC116500127
uniprot id: A0A6J3EB65
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

219594:PURA
gene id: 219594:PURA
uniprot id: A0A6J3DU80
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PUR DNA-binding protein family.
messages: Nucleus

219594:MMGT1
gene id: 219594:MMGT1
uniprot id: A0A6J3DRM6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane magnesium transporter (TC 1.A.67) family.
messages: Early endosome membrane
messages: Endosome membrane
messages: Golgi apparatus membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the endoplasmic reticulum membrane protein complex (EMC) that enables the energy-independent insertion into endoplasmic reticulum membranes of newly synthesized membrane proteins. May be involved in Mg(2+) transport.

219594:ATP5F1B
gene id: 219594:ATP5F1B
uniprot id: A0A6J3EFE8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

219594:SEMA4B
gene id: 219594:SEMA4B
uniprot id: A0A6J3DK33
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:MTMR4
gene id: 219594:MTMR4
uniprot id: A0A6J3E0F4
uniprot id: A0A6J3E330
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily.
messages: Cytoplasm
messages: Membrane

219594:LOC116499322
gene id: 219594:LOC116499322
uniprot id: A0A6J3ECW1
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:FAN1
gene id: 219594:FAN1
uniprot id: A0A6J3DHN5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAN1 family.
messages: Nuclease required for the repair of DNA interstrand cross-links (ICL). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions.
messages: Nucleus

219594:RIDA
gene id: 219594:RIDA
uniprot id: A0A6J3CK66
names: Function
names: Similarity
messages: Belongs to the RutC family.
messages: Catalyzes the hydrolytic deamination of enamine/imine intermediates that form during the course of normal metabolism. May facilitate the release of ammonia from these potentially toxic reactive metabolites, reducing their impact on cellular components. It may act on enamine/imine intermediates formed by several types of pyridoxal-5'-phosphate-dependent dehydratases including L-threonine dehydratase.

219594:LOC116498202
gene id: 219594:LOC116498202
uniprot id: A0A6J3E8Y5
names: Similarity
messages: Belongs to the peptidase C1 family.

219594:VLDLR
gene id: 219594:VLDLR
uniprot id: A0A6J3EHM5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:GASK1B
gene id: 219594:GASK1B
uniprot id: A0A6J3CXM8
names: Similarity
messages: Belongs to the GASK family.

219594:LOC116497445
gene id: 219594:LOC116497445
uniprot id: A0A6J3E1U3
names: Similarity
names: Subunit
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Homotetramer.

219594:HACD2
gene id: 219594:HACD2
uniprot id: A0A6J3D2W1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the very long-chain fatty acids dehydratase HACD family.
messages: Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

219594:LOC116500308
gene id: 219594:LOC116500308
uniprot id: A0A6J3EIC1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

219594:LOC116490923
gene id: 219594:LOC116490923
uniprot id: A0A6J3D842
names: Subunit
messages: Monomer.

219594:RNF170
gene id: 219594:RNF170
uniprot id: A0A6J3ED27
uniprot id: A0A6J3EHW9
uniprot id: A0A6J3EJV4
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

219594:SKIL
gene id: 219594:SKIL
uniprot id: A0A6J3DCA0
names: Similarity
messages: Belongs to the SKI family.

219594:WASF2
gene id: 219594:WASF2
uniprot id: A0A6J3E9Y9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SCAR/WAVE family.
messages: Binds actin and the Arp2/3 complex.
messages: Downstream effector molecule involved in the transmission of signals from tyrosine kinase receptors and small GTPases to the actin cytoskeleton. Promotes formation of actin filaments. Part of the WAVE complex that regulates lamellipodia formation. The WAVE complex regulates actin filament reorganization via its interaction with the Arp2/3 complex.
messages: cytoskeleton

219594:QARS1
gene id: 219594:QARS1
uniprot id: A0A6J3DLS8
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

219594:LOC116490057
gene id: 219594:LOC116490057
uniprot id: A0A6J3D6E9
names: Similarity
messages: Belongs to the serpin family.

219594:LOC116492034
gene id: 219594:LOC116492034
uniprot id: A0A6J3DG01
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c-type heme lyase family.
messages: Lyase that catalyzes the covalent linking of the heme group to the cytochrome C apoprotein to produce the mature functional cytochrome.
messages: Membrane
messages: Mitochondrion inner membrane

219594:ARSK
gene id: 219594:ARSK
uniprot id: A0A6J3EK06
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfatase family.
messages: Lysosome

219594:TBX10
gene id: 219594:TBX10
uniprot id: A0A6J3D3N4
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

219594:ADGRV1
gene id: 219594:ADGRV1
uniprot id: A0A6J3EHF2
names: Subcellular Location Annotation
messages: Membrane

219594:PTPRU
gene id: 219594:PTPRU
uniprot id: A0A6J3E4Y3
uniprot id: A0A6J3E7U8
uniprot id: A0A6J3E9Y0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Receptor class 2B subfamily.
messages: Membrane

219594:ADGRL4
gene id: 219594:ADGRL4
uniprot id: A0A6J3DD90
uniprot id: A0A6J3DEB4
uniprot id: A0A6J3DGG4
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 2 family. Adhesion G-protein coupled receptor (ADGR) subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

219594:HIP1
gene id: 219594:HIP1
uniprot id: A0A6J3E4L8
uniprot id: A0A6J3E5M6
names: Similarity
messages: Belongs to the SLA2 family.

219594:TGFBR2
gene id: 219594:TGFBR2
uniprot id: A0A6J3CJ96
uniprot id: A0A6J3CKG5
uniprot id: A0A6J3CME8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
messages: Cell membrane
messages: Membrane
messages: Membrane raft
messages: Transmembrane serine/threonine kinase forming with the TGF-beta type I serine/threonine kinase receptor, TGFBR1, the non-promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinogenesis. The formation of the receptor complex composed of 2 TGFBR1 and 2 TGFBR2 molecules symmetrically bound to the cytokine dimer results in the phosphorylation and the activation of TGFRB1 by the constitutively active TGFBR2. Activated TGFBR1 phosphorylates SMAD2 which dissociates from the receptor and interacts with SMAD4. The SMAD2-SMAD4 complex is subsequently translocated to the nucleus where it modulates the transcription of the TGF-beta-regulated genes. This constitutes the canonical SMAD-dependent TGF-beta signaling cascade. Also involved in non-canonical, SMAD-independent TGF-beta signaling pathways.

219594:LOC116493826
gene id: 219594:LOC116493826
uniprot id: A0A6J3DNX8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAF4 family.
messages: Nucleus

219594:LOC116497573
gene id: 219594:LOC116497573
uniprot id: A0A6J3E126
uniprot id: A0A6J3E629
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class 2 subfamily.
messages: Cytoplasm

219594:ELF1
gene id: 219594:ELF1
uniprot id: A0A6J3EHS6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

219594:LOC116495144
gene id: 219594:LOC116495144
uniprot id: A0A6J3DPC1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MAL family.
messages: Membrane

219594:EPHX1
gene id: 219594:EPHX1
uniprot id: A0A6J3CR72
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S33 family.
messages: Biotransformation enzyme that catalyzes the hydrolysis of arene and aliphatic epoxides to less reactive and more water soluble dihydrodiols by the trans addition of water.
messages: Endoplasmic reticulum membrane
messages: Microsome membrane

219594:SYNCRIP
gene id: 219594:SYNCRIP
uniprot id: A0A6J3CNN6
uniprot id: A0A6J3CPL0
uniprot id: A0A6J3CRV9
uniprot id: A0A6J3CRW3
uniprot id: A0A6J3CSY0
names: Subcellular Location Annotation
messages: Cytoplasm

219594:RBM48
gene id: 219594:RBM48
uniprot id: A0A6J3CI59
names: Function
names: Similarity
messages: As a component of the minor spliceosome, involved in the splicing of U12-type introns in pre-mRNAs.
messages: Belongs to the RBM48 family.

219594:KCNA2
gene id: 219594:KCNA2
uniprot id: A0A6J3ECB6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the potassium channel family. A (Shaker) (TC 1.A.1.2) subfamily. Kv1.2/KCNA2 sub-subfamily.
messages: Cell membrane
messages: Membrane

219594:LOC116489176
gene id: 219594:LOC116489176
uniprot id: A0A6J3CYA5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

219594:EN2
gene id: 219594:EN2
uniprot id: A0A6J3CC78
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Engrailed homeobox family.
messages: Nucleus

219594:LOC116499727
gene id: 219594:LOC116499727
uniprot id: A0A6J3E9H2
names: Similarity
names: Subunit
messages: Belongs to the avian keratin family.
messages: The avian keratins (F-ker, S-ker, C-ker and B-ker) are a complex mixture of very similar polypeptides.

219594:ACVR1
gene id: 219594:ACVR1
uniprot id: A0A6J3D5S1
uniprot id: A0A6J3D654
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
messages: Membrane

219594:CIAO1
gene id: 219594:CIAO1
uniprot id: A0A6J3ED71
names: Function
names: Similarity
names: Subunit
messages: Belongs to the WD repeat CIA1 family.
messages: Component of the CIA complex.
messages: Key component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into extramitochondrial Fe/S proteins.

219594:LIPA
gene id: 219594:LIPA
uniprot id: A0A6J3DC06
names: Similarity
messages: Belongs to the AB hydrolase superfamily. Lipase family.

219594:LOC116486056
gene id: 219594:LOC116486056
uniprot id: A0A6J3CHG4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2B family.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

219594:GJA1
gene id: 219594:GJA1
uniprot id: A0A6J3CRD1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family. Alpha-type (group II) subfamily.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

219594:MFNG
gene id: 219594:MFNG
uniprot id: A0A6J3EK44
uniprot id: A0A6J3EK87
uniprot id: A0A6J3EK97
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane

219594:SLC9A9
gene id: 219594:SLC9A9
uniprot id: A0A6J3DJD9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.
messages: Cell membrane
messages: Endosome membrane
messages: Recycling endosome membrane

219594:RER1
gene id: 219594:RER1
uniprot id: A0A6J3E5M4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RER1 family.
messages: Involved in the retrieval of endoplasmic reticulum membrane proteins from the early Golgi compartment.
messages: Membrane

219594:ZC3H14
gene id: 219594:ZC3H14
uniprot id: A0A6J3D679
uniprot id: A0A6J3D738
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZC3H14 family.
messages: Involved in poly(A) tail length control in neuronal cells. Binds the polyadenosine RNA oligonucleotides.
messages: Nucleus speckle

219594:LOC116500147
gene id: 219594:LOC116500147
uniprot id: A0A6J3EGA3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

219594:NFASC
gene id: 219594:NFASC
uniprot id: A0A6J3E695
uniprot id: A0A6J3E699
uniprot id: A0A6J3E6A3
uniprot id: A0A6J3E6A8
uniprot id: A0A6J3E6B5
uniprot id: A0A6J3E7T2
uniprot id: A0A6J3E7T7
uniprot id: A0A6J3E7U1
uniprot id: A0A6J3EAS4
uniprot id: A0A6J3EAS9
uniprot id: A0A6J3EAT4
uniprot id: A0A6J3EAT8
uniprot id: A0A6J3EAU3
uniprot id: A0A6J3EBB9
uniprot id: A0A6J3EBC4
uniprot id: A0A6J3EBD0
uniprot id: A0A6J3EBD5
uniprot id: A0A6J3ECY6
uniprot id: A0A6J3ECZ7
uniprot id: A0A6J3ECZ8
names: Similarity
messages: Belongs to the immunoglobulin superfamily. L1/neurofascin/NgCAM family.

219594:GATA5
gene id: 219594:GATA5
uniprot id: A0A6J3DUP6
uniprot id: A0A6J3DWX9
names: Subcellular Location Annotation
messages: Nucleus

219594:LOC116500179
gene id: 219594:LOC116500179
uniprot id: A0A6J3EG26
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the immunoglobulin superfamily. BTN/MOG family.
messages: Membrane

219594:LOC116487948
gene id: 219594:LOC116487948
uniprot id: A0A6J3ENP0
names: Similarity
names: Subunit
messages: Belongs to the histone H3 family.
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

219594:ND5
gene id: 219594:ND5
uniprot id: A0A068LAU4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 5 family.
messages: Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor. Essential for the catalytic activity and assembly of complex I.
messages: Membrane
messages: Mitochondrion inner membrane

219594:MRPL40
gene id: 219594:MRPL40
uniprot id: A0A6J3DX14
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mL40 family.
messages: Mitochondrion

219594:LOC116489923
gene id: 219594:LOC116489923
uniprot id: A0A6J3D2E2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protease inhibitor I39 (alpha-2-macroglobulin) family.
messages: Secreted

219594:PSMB1
gene id: 219594:PSMB1
uniprot id: A0A6J3CTD3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1B family.
messages: Component of the proteasome complex.
messages: Component of the proteasome, a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.
messages: Cytoplasm
messages: Nucleus

219594:TBC1D31
gene id: 219594:TBC1D31
uniprot id: A0A6J3CGV4
uniprot id: A0A6J3CLE2
uniprot id: A0A6J3CN06
names: Function
names: Subcellular Location Annotation
messages: Molecular adapter which is involved in cilium biogenesis. Part of a functional complex including OFD1 a centriolar protein involved in cilium assembly. Could regulate the cAMP-dependent phosphorylation of OFD1, and its subsequent ubiquitination by PJA2 which ultimately leads to its proteasomal degradation.
messages: centriolar satellite
messages: cilium basal body

219594:USP5
gene id: 219594:USP5
uniprot id: A0A6J3DU54
names: Similarity
messages: Belongs to the peptidase C19 family.

219594:LANCL1
gene id: 219594:LANCL1
uniprot id: A0A6J3DA42
names: Similarity
messages: Belongs to the LanC-like protein family.

219594:PFKL
gene id: 219594:PFKL
uniprot id: A0A6J3DFX7
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by ADP, AMP, or fructose 2,6-bisphosphate, and allosterically inhibited by ATP or citrate.
messages: Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade "E" sub-subfamily.
messages: Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homo- and heterotetramers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:LGI2
gene id: 219594:LGI2
uniprot id: A0A6J3CZ87
names: Subcellular Location Annotation
messages: Secreted

219594:LOC116486653
gene id: 219594:LOC116486653
uniprot id: A0A6J3CLM1
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:CDH20
gene id: 219594:CDH20
uniprot id: A0A6J3CM64
names: Function
names: Subcellular Location Annotation
messages: Cadherins are calcium-dependent cell adhesion proteins.
messages: Cell membrane

219594:PIGG
gene id: 219594:PIGG
uniprot id: A0A6J3EE77
uniprot id: A0A6J3EHP7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PIGG/PIGN/PIGO family. PIGG subfamily.
messages: Endoplasmic reticulum membrane
messages: Membrane

219594:LOC116496126
gene id: 219594:LOC116496126
uniprot id: A0A6J3DZ39
names: Similarity
messages: Belongs to the alpha-carbonic anhydrase family.

219594:NOP58
gene id: 219594:NOP58
uniprot id: A0A6J3D7V8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NOP5/NOP56 family.
messages: nucleolus

219594:MACIR
gene id: 219594:MACIR
uniprot id: A0A6J3ELW8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UNC119-binding protein family.
messages: Cytoplasm
messages: cilium

219594:LOC116495944
gene id: 219594:LOC116495944
uniprot id: A0A6J3DY33
names: Similarity
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.

219594:FGGY
gene id: 219594:FGGY
uniprot id: A0A6J3DGX7
names: Similarity
messages: Belongs to the FGGY kinase family.

219594:LOC116501328
gene id: 219594:LOC116501328
uniprot id: A0A6J3EG78
names: Subcellular Location Annotation
messages: Membrane

219594:GLE1
gene id: 219594:GLE1
uniprot id: A0A6J3E4H2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GLE1 family.
messages: Required for the export of mRNAs containing poly(A) tails from the nucleus into the cytoplasm. May be involved in the terminal step of the mRNA transport through the nuclear pore complex (NPC).
messages: nuclear pore complex

219594:GTF2IRD1
gene id: 219594:GTF2IRD1
uniprot id: A0A6J3E079
uniprot id: A0A6J3E1M3
uniprot id: A0A6J3E4E2
uniprot id: A0A6J3E588
uniprot id: A0A6J3E6A4
names: Subcellular Location Annotation
messages: Nucleus

219594:IL4R
gene id: 219594:IL4R
uniprot id: A0A6J3DUX9
uniprot id: A0A6J3DVT0
names: Function
names: Similarity
messages: Belongs to the type I cytokine receptor family. Type 4 subfamily.
messages: Receptor for both interleukin 4 and interleukin 13. Couples to the JAK1/2/3-STAT6 pathway. The IL4 response is involved in promoting Th2 differentiation. The IL4/IL13 responses are involved in regulating IgE production and, chemokine and mucus production at sites of allergic inflammation. In certain cell types, can signal through activation of insulin receptor substrates, IRS1/IRS2.

219594:VAMP1
gene id: 219594:VAMP1
uniprot id: A0A6J3EHS8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptobrevin family.
messages: Membrane

219594:MAPRE2
gene id: 219594:MAPRE2
uniprot id: A0A6J3CFC3
uniprot id: A0A6J3CI78
uniprot id: A0A6J3CJX2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MAPRE family.
messages: cytoskeleton

219594:ATRNL1
gene id: 219594:ATRNL1
uniprot id: A0A6J3D5S5
uniprot id: A0A6J3D8H5
uniprot id: A0A6J3D901
uniprot id: A0A6J3DB61
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:NKX1-2
gene id: 219594:NKX1-2
uniprot id: A0A6J3DCB7
names: Subcellular Location Annotation
messages: Nucleus

219594:EXT2
gene id: 219594:EXT2
uniprot id: A0A6J3D0T9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 47 family.
messages: Endoplasmic reticulum membrane

219594:POLR2F
gene id: 219594:POLR2F
uniprot id: A0A6J3DF93
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the archaeal Rpo6/eukaryotic RPB6 RNA polymerase subunit family.
messages: Component of the RNA polymerase I (Pol I), RNA polymerase II (Pol II) and RNA polymerase III (Pol III) complexes consisting of at least 13, 12 and 17 subunits, respectively.
messages: Nucleus

219594:HSD17B3
gene id: 219594:HSD17B3
uniprot id: A0A6J3EGK4
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

219594:GBA
gene id: 219594:GBA
uniprot id: A0A6J3EE42
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 30 family.
messages: Lysosome membrane

219594:LOC116490067
gene id: 219594:LOC116490067
uniprot id: A0A6J3D303
names: Domain
names: Subcellular Location Annotation
messages: The N-terminal C2 domain associates with lipid membranes upon calcium binding.
messages: cytosol

219594:BMP1
gene id: 219594:BMP1
uniprot id: A0A6J3E8Q8
names: Caution
names: Cofactor
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:ELAVL4
gene id: 219594:ELAVL4
uniprot id: A0A6J3D8X9
uniprot id: A0A6J3D8Y4
uniprot id: A0A6J3D8Y6
uniprot id: A0A6J3DBN7
uniprot id: A0A6J3DBP1
uniprot id: A0A6J3DCL1
uniprot id: A0A6J3DEM9
uniprot id: A0A6J3DEN4
uniprot id: A0A6J3DEV4
uniprot id: A0A6J3DEV7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRM elav family.
messages: Cytoplasm
messages: Perikaryon
messages: axon
messages: dendrite
messages: growth cone

219594:PPP1CA
gene id: 219594:PPP1CA
uniprot id: A0A6J3D3Y6
names: Similarity
messages: Belongs to the PPP phosphatase family. PP-1 subfamily.

219594:PDGFA
gene id: 219594:PDGFA
uniprot id: A0A6J3DV49
uniprot id: A0A6J3DV53
uniprot id: A0A6J3DW12
names: Similarity
messages: Belongs to the PDGF/VEGF growth factor family.

219594:RXFP2
gene id: 219594:RXFP2
uniprot id: A0A6J3ENL4
names: Caution
names: Subcellular Location Annotation
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

219594:LOC116493988
gene id: 219594:LOC116493988
uniprot id: A0A6J3DQH0
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

219594:OCRL
gene id: 219594:OCRL
uniprot id: A0A6J3DNX7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inositol 1,4,5-trisphosphate 5-phosphatase type II family.
messages: Early endosome membrane
messages: Endosome membrane
messages: Membrane
messages: phagosome membrane

219594:SLC12A5
gene id: 219594:SLC12A5
uniprot id: A0A6J3DXY9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC12A transporter family.
messages: Membrane

219594:GABRD
gene id: 219594:GABRD
uniprot id: A0A6J3E5R9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

219594:COX2
gene id: 219594:COX2
uniprot id: A0A068L8F7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 2 family.
messages: Binds a copper A center.
messages: Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)). The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
messages: Membrane
messages: Mitochondrion inner membrane

219594:UNC5D
gene id: 219594:UNC5D
uniprot id: A0A6J3EF24
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the unc-5 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for netrin required for axon guidance. Mediates axon repulsion of neuronal growth cones in the developing nervous system upon ligand binding.

219594:IL17D
gene id: 219594:IL17D
uniprot id: A0A6J3EN11
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IL-17 family.
messages: Secreted

219594:B4GALNT3
gene id: 219594:B4GALNT3
uniprot id: A0A6J3CRF2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chondroitin N-acetylgalactosaminyltransferase family.
messages: Golgi stack membrane
messages: Membrane
messages: Transfers N-acetylgalactosamine (GalNAc) from UDP-GalNAc to N-acetylglucosamine-beta-benzyl with a beta-1,4-linkage to form N,N'-diacetyllactosediamine, GalNAc-beta-1,4-GlcNAc structures in N-linked glycans and probably O-linked glycans.

219594:PHACTR1
gene id: 219594:PHACTR1
uniprot id: A0A6J3CGC6
uniprot id: A0A6J3CHB0
uniprot id: A0A6J3CJ81
names: Similarity
names: Subunit
messages: Belongs to the phosphatase and actin regulator family.
messages: Binds PPP1CA and actin.

219594:MYO1E
gene id: 219594:MYO1E
uniprot id: A0A6J3DGS1
uniprot id: A0A6J3DKU2
uniprot id: A0A6J3DMA1
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.

219594:LOC116501157
gene id: 219594:LOC116501157
uniprot id: A0A6J3EFG0
names: Function
names: Miscellaneous
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a sulfur carrier required for molybdopterin biosynthesis. Component of the molybdopterin synthase complex that catalyzes the conversion of precursor Z into molybdopterin by mediating the incorporation of 2 sulfur atoms into precursor Z to generate a dithiolene group. In the complex, serves as sulfur donor by being thiocarboxylated (-COSH) at its C-terminus by MOCS3. After interaction with MOCS2B, the sulfur is then transferred to precursor Z to form molybdopterin.
messages: Belongs to the MoaD family. MOCS2A subfamily.
messages: C-terminal thiocarboxylation occurs in 2 steps, it is first acyl-adenylated (-COAMP) via the hesA/moeB/thiF part of MOCS3, then thiocarboxylated (-COSH) via the rhodanese domain of MOCS3.
messages: Heterotetramer; composed of 2 small (MOCS2A) and 2 large (MOCS2B) subunits.
messages: This protein is produced by a bicistronic gene which also produces the large subunit (MOCS2B).
messages: cytosol

219594:RPS6KB1
gene id: 219594:RPS6KB1
uniprot id: A0A6J3E0W5
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily.

219594:HOXC13
gene id: 219594:HOXC13
uniprot id: A0A6J3EHE5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Abd-B homeobox family.
messages: Nucleus

219594:ALKBH8
gene id: 219594:ALKBH8
uniprot id: A0A6J3DTA7
uniprot id: A0A6J3DU83
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alkB family.
messages: Cytoplasm

219594:NDST2
gene id: 219594:NDST2
uniprot id: A0A6J3D7R2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 1 family. NDST subfamily.
messages: Membrane

219594:CD8B
gene id: 219594:CD8B
uniprot id: A0A6J3CZ33
names: Subcellular Location Annotation
messages: Membrane

219594:LRP12
gene id: 219594:LRP12
uniprot id: A0A6J3CFC8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:NDOR1
gene id: 219594:NDOR1
uniprot id: A0A6J3DZW0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NADPH-dependent diflavin oxidoreductase NDOR1 family.
messages: In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
messages: In the N-terminal section; belongs to the flavodoxin family.
messages: Interacts with CIAPIN1; as part of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NADPH-dependent reductase which is a central component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery. Transfers electrons from NADPH via its FAD and FMN prosthetic groups to the [2Fe-2S] cluster of CIAPIN1, another key component of the CIA machinery. In turn, this reduced cluster provides electrons for assembly of cytosolic iron-sulfur cluster proteins. It can also reduce the [2Fe-2S] cluster of CISD1 and activate this protein implicated in Fe/S cluster repair.
messages: perinuclear region

219594:AGTR1
gene id: 219594:AGTR1
uniprot id: A0A6J3DGI2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for angiotensin II, a vasoconstricting peptide, which acts as a key regulator of blood pressure and sodium retention by the kidney. The activated receptor in turn couples to G-alpha proteins G(q) and thus activates phospholipase C and increases the cytosolic Ca(2+) concentrations, which in turn triggers cellular responses such as stimulation of protein kinase C.

219594:ENO4
gene id: 219594:ENO4
uniprot id: A0A6J3D6T1
names: Similarity
messages: Belongs to the enolase family.

219594:FOXK1
gene id: 219594:FOXK1
uniprot id: A0A6J3DVE1
names: Subcellular Location Annotation
messages: Nucleus

219594:OAZ1
gene id: 219594:OAZ1
uniprot id: A0A6J3E7L0
names: Similarity
messages: Belongs to the ODC antizyme family.

219594:ING5
gene id: 219594:ING5
uniprot id: A0A6J3DH87
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ING family.
messages: Component of an histone acetyltransferase complex.
messages: Component of an histone acetyltransferase complex. Interacts with H3K4me3 and to a lesser extent with H3K4me2.
messages: Nucleus
messages: The PHD-type zinc finger mediates the binding to H3K4me3.

219594:ATP6AP2
gene id: 219594:ATP6AP2
uniprot id: A0A6J3E6J9
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Lysosome membrane
messages: Membrane
messages: autophagosome membrane
messages: clathrin-coated vesicle membrane
messages: dendritic spine membrane
messages: synaptic vesicle membrane

219594:LOC116488578
gene id: 219594:LOC116488578
uniprot id: A0A6J3CVH0
names: Similarity
messages: Belongs to the HPF1 family.

219594:ADGRG2
gene id: 219594:ADGRG2
uniprot id: A0A6J3EJN4
uniprot id: A0A6J3EQ13
uniprot id: A0A6J3EQ19
uniprot id: A0A6J3ERH0
names: Subcellular Location Annotation
messages: Membrane

219594:POLR2D
gene id: 219594:POLR2D
uniprot id: A0A6J3DHS3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic RPB4 RNA polymerase subunit family.
messages: Nucleus

219594:TAGLN2
gene id: 219594:TAGLN2
uniprot id: A0A6J3EBE3
names: Similarity
messages: Belongs to the calponin family.

219594:FUNDC1
gene id: 219594:FUNDC1
uniprot id: A0A6J3DE58
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FUN14 family.
messages: Mitochondrion outer membrane

219594:LOC116500317
gene id: 219594:LOC116500317
uniprot id: A0A6J3EGT0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

219594:RAB19
gene id: 219594:RAB19
uniprot id: A0A6J3DTN7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Membrane

219594:SLC39A3
gene id: 219594:SLC39A3
uniprot id: A0A6J3EBS7
names: Subcellular Location Annotation
messages: Membrane

219594:TNMD
gene id: 219594:TNMD
uniprot id: A0A6J3DQ09
names: Similarity
messages: Belongs to the chondromodulin-1 family.

219594:UROD
gene id: 219594:UROD
uniprot id: A0A6J3D8X6
names: Similarity
names: Subunit
messages: Belongs to the uroporphyrinogen decarboxylase family.
messages: Homodimer.

219594:ASIC4
gene id: 219594:ASIC4
uniprot id: A0A6J3D729
uniprot id: A0A6J3D9S6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family.
messages: Membrane

219594:LDB2
gene id: 219594:LDB2
uniprot id: A0A6J3CTS7
uniprot id: A0A6J3CTT0
uniprot id: A0A6J3CW27
uniprot id: A0A6J3CWG9
uniprot id: A0A6J3CZV7
uniprot id: A0A6J3CZW1
names: Similarity
messages: Belongs to the LDB family.

219594:LOC116490405
gene id: 219594:LOC116490405
uniprot id: A0A6J3D4N5
uniprot id: A0A6J3D791
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

219594:CRELD2
gene id: 219594:CRELD2
uniprot id: A0A6J3EFX6
names: Caution
names: Similarity
messages: Belongs to the CRELD family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:WHAMM
gene id: 219594:WHAMM
uniprot id: A0A6J3DHD6
names: Subcellular Location Annotation
messages: Membrane

219594:MTO1
gene id: 219594:MTO1
uniprot id: A0A6J3CXE1
names: Function
names: Similarity
messages: Belongs to the MnmG family.
messages: Involved in the 5-carboxymethylaminomethyl modification (mnm(5)s(2)U34) of the wobble uridine base in mitochondrial tRNAs.

219594:LOC116497359
gene id: 219594:LOC116497359
uniprot id: A0A6J3E487
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the intercrine beta (chemokine CC) family.
messages: Secreted

219594:PPFIA4
gene id: 219594:PPFIA4
uniprot id: A0A6J3E5W1
uniprot id: A0A6J3EAC8
names: Similarity
messages: Belongs to the liprin family. Liprin-alpha subfamily.

219594:RHBDF1
gene id: 219594:RHBDF1
uniprot id: A0A6J3DV83
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S54 family.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Regulates ADAM17 protease, a sheddase of the epidermal growth factor (EGF) receptor ligands and TNF, thereby plays a role in sleep, cell survival, proliferation, migration and inflammation. Does not exhibit any protease activity on its own.

219594:DARS2
gene id: 219594:DARS2
uniprot id: A0A6J3DGL8
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.

219594:PTDSS1
gene id: 219594:PTDSS1
uniprot id: A0A6J3CFR9
uniprot id: A0A6J3CGQ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phosphatidyl serine synthase family.
messages: Catalyzes a base-exchange reaction in which the polar head group of phosphatidylethanolamine (PE) is replaced by L-serine.
messages: Endoplasmic reticulum membrane
messages: Membrane

219594:MCRIP2
gene id: 219594:MCRIP2
uniprot id: A0A6J3DST0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MCRIP family.
messages: Nucleus
messages: Stress granule

219594:LOC116500116
gene id: 219594:LOC116500116
uniprot id: A0A6J3EG72
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

219594:STEAP1
gene id: 219594:STEAP1
uniprot id: A0A6J3CHT7
names: Subcellular Location Annotation
messages: Membrane

219594:CEMIP2
gene id: 219594:CEMIP2
uniprot id: A0A6J3EE82
names: Similarity
messages: Belongs to the CEMIP family.

219594:LOC116500193
gene id: 219594:LOC116500193
uniprot id: A0A6J3EGF1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2A family.
messages: Chromosome
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

219594:SNTA1
gene id: 219594:SNTA1
uniprot id: A0A6J3DTX9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the syntrophin family.
messages: Cell junction
messages: cytoskeleton

219594:MADD
gene id: 219594:MADD
uniprot id: A0A6J3CZW2
uniprot id: A0A6J3CZW7
uniprot id: A0A6J3CZX2
uniprot id: A0A6J3CZX9
uniprot id: A0A6J3CZY4
uniprot id: A0A6J3CZZ3
uniprot id: A0A6J3D2A0
uniprot id: A0A6J3D2A8
uniprot id: A0A6J3D2B3
uniprot id: A0A6J3D2B8
uniprot id: A0A6J3D2C2
uniprot id: A0A6J3D2E1
uniprot id: A0A6J3D2E9
uniprot id: A0A6J3D2G2
uniprot id: A0A6J3D2H0
uniprot id: A0A6J3D2H3
uniprot id: A0A6J3D4S5
uniprot id: A0A6J3D4T0
uniprot id: A0A6J3D4T5
uniprot id: A0A6J3D4U0
uniprot id: A0A6J3D4U5
uniprot id: A0A6J3D4V0
uniprot id: A0A6J3D5R2
uniprot id: A0A6J3D5R7
uniprot id: A0A6J3D5S2
uniprot id: A0A6J3D5S7
uniprot id: A0A6J3D5T2
uniprot id: A0A6J3D5T8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MADD family.
messages: Cell membrane
messages: Cytoplasm
messages: Membrane

219594:ETS2
gene id: 219594:ETS2
uniprot id: A0A6J3EKH2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus
messages: Transcription factor.

219594:TBX21
gene id: 219594:TBX21
uniprot id: A0A6J3E923
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

219594:MTNR1B
gene id: 219594:MTNR1B
uniprot id: A0A6J3EJ66
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

219594:MOCS3
gene id: 219594:MOCS3
uniprot id: A0A6J3DWA8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: In the N-terminal section; belongs to the HesA/MoeB/ThiF family. UBA4 subfamily.
messages: Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Also essential during biosynthesis of the molybdenum cofactor. Acts by mediating the C-terminal thiocarboxylation of sulfur carriers URM1 and MOCS2A. Its N-terminus first activates URM1 and MOCS2A as acyl-adenylates (-COAMP), then the persulfide sulfur on the catalytic cysteine is transferred to URM1 and MOCS2A to form thiocarboxylation (-COSH) of their C-terminus. The reaction probably involves hydrogen sulfide that is generated from the persulfide intermediate and that acts as nucleophile towards URM1 and MOCS2A. Subsequently, a transient disulfide bond is formed. Does not use thiosulfate as sulfur donor; NFS1 probably acting as a sulfur donor for thiocarboxylation reactions.

219594:PTK2
gene id: 219594:PTK2
uniprot id: A0A6J3CCL8
uniprot id: A0A6J3CE90
uniprot id: A0A6J3CF89
uniprot id: A0A6J3CFA3
uniprot id: A0A6J3CH37
uniprot id: A0A6J3CH42
uniprot id: A0A6J3CH53
uniprot id: A0A6J3CIV8
uniprot id: A0A6J3CIW3
uniprot id: A0A6J3CIW8
names: Subcellular Location Annotation
messages: Cell membrane
messages: focal adhesion

219594:HPRT1
gene id: 219594:HPRT1
uniprot id: A0A6J3DMZ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm

219594:EYA4
gene id: 219594:EYA4
uniprot id: A0A6J3CT92
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HAD-like hydrolase superfamily. EYA family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Nucleus

219594:RPL14
gene id: 219594:RPL14
uniprot id: A0A6J3CKD9
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL14 family.

219594:LOC116499880
gene id: 219594:LOC116499880
uniprot id: A0A6J3EFC8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

219594:MYCL
gene id: 219594:MYCL
uniprot id: A0A6J3E5B7
names: Subcellular Location Annotation
names: Subunit
messages: Efficient DNA binding requires dimerization with another bHLH protein.
messages: Nucleus

219594:CASK
gene id: 219594:CASK
uniprot id: A0A6J3DG42
uniprot id: A0A6J3DK30
uniprot id: A0A6J3DK51
uniprot id: A0A6J3DK66
uniprot id: A0A6J3DK75
uniprot id: A0A6J3DLQ5
uniprot id: A0A6J3DM43
names: Similarity
messages: Belongs to the MAGUK family.

219594:POGLUT3
gene id: 219594:POGLUT3
uniprot id: A0A6J3DVY0
names: Similarity
messages: Belongs to the KDELC family.

219594:SMARCAL1
gene id: 219594:SMARCAL1
uniprot id: A0A6J3D7I4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNF2/RAD54 helicase family. SMARCAL1 subfamily.
messages: Nucleus

219594:MLN
gene id: 219594:MLN
uniprot id: A0A6J3E7Z8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the motilin family.
messages: Plays an important role in the regulation of interdigestive gastrointestinal motility and indirectly causes rhythmic contraction of duodenal and colonic smooth muscle.
messages: Secreted

219594:LOC116501377
gene id: 219594:LOC116501377
uniprot id: A0A6J3EGC6
uniprot id: A0A6J3ELL1
uniprot id: A0A6J3ELP3
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

219594:LOC116485706
gene id: 219594:LOC116485706
uniprot id: A0A6J3CDM4
names: Cofactor
names: PTM
names: Similarity
messages: Belongs to the paraoxonase family.
messages: Binds 2 calcium ions per subunit.
messages: Glycosylated.

219594:FUT6
gene id: 219594:FUT6
uniprot id: A0A6J3E7U4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 10 family.
messages: Golgi stack membrane

219594:IPO9
gene id: 219594:IPO9
uniprot id: A0A6J3E6W7
names: Subcellular Location Annotation
messages: Cytoplasm

219594:ENPEP
gene id: 219594:ENPEP
uniprot id: A0A6J3D0Q1
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M1 family.
messages: Binds 1 zinc ion per subunit.

219594:ADRA2B
gene id: 219594:ADRA2B
uniprot id: A0A6J3EEZ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

219594:ANKRD34C
gene id: 219594:ANKRD34C
uniprot id: A0A6J3DPG0
names: Similarity
messages: Belongs to the ANKRD34 family.

219594:MRPL50
gene id: 219594:MRPL50
uniprot id: A0A6J3EKV5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mL50 family.
messages: Mitochondrion

219594:LOC116486477
gene id: 219594:LOC116486477
uniprot id: A0A6J3CP54
names: Function
names: Similarity
messages: Belongs to the alpha-carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

219594:LOC116485793
gene id: 219594:LOC116485793
uniprot id: A0A6J3CFX4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.
messages: cytoskeleton

219594:TRAK1
gene id: 219594:TRAK1
uniprot id: A0A6J3CFI5
uniprot id: A0A6J3CJ60
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the milton family.
messages: Early endosome
messages: Mitochondrion

219594:GRK3
gene id: 219594:GRK3
uniprot id: A0A6J3DV56
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily.

219594:MORF4L1
gene id: 219594:MORF4L1
uniprot id: A0A6J3DGN9
uniprot id: A0A6J3DJA2
uniprot id: A0A6J3DKQ4
names: Subcellular Location Annotation
messages: Nucleus

219594:LOC116491639
gene id: 219594:LOC116491639
uniprot id: A0A6J3DB04
names: Caution
names: Cofactor
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:RSPO2
gene id: 219594:RSPO2
uniprot id: A0A6J3CMA1
names: Similarity
messages: Belongs to the R-spondin family.

219594:ADIPOR2
gene id: 219594:ADIPOR2
uniprot id: A0A6J3CXP3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ADIPOR family.
messages: Membrane

219594:DHFR
gene id: 219594:DHFR
uniprot id: A0A6J3EEX1
names: Similarity
messages: Belongs to the dihydrofolate reductase family.

219594:DYNLT3
gene id: 219594:DYNLT3
uniprot id: A0A6J3DZX0
names: Similarity
messages: Belongs to the dynein light chain Tctex-type family.

219594:LOC116491457
gene id: 219594:LOC116491457
uniprot id: A0A6J3DA50
names: Similarity
messages: Belongs to the cystatin family.

219594:AP1B1
gene id: 219594:AP1B1
uniprot id: A0A6J3DT67
uniprot id: A0A6J3DV54
uniprot id: A0A6J3DXC6
names: Similarity
messages: Belongs to the adaptor complexes large subunit family.

219594:LOC116495790
gene id: 219594:LOC116495790
uniprot id: A0A6J3DYP0
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

219594:KCNG3
gene id: 219594:KCNG3
uniprot id: A0A6J3CPM2
uniprot id: A0A6J3CRX2
names: Subcellular Location Annotation
messages: Membrane

219594:CEPT1
gene id: 219594:CEPT1
uniprot id: A0A6J3EAX0
uniprot id: A0A6J3ECG9
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

219594:DCP1B
gene id: 219594:DCP1B
uniprot id: A0A6J3D3R2
names: Similarity
messages: Belongs to the DCP1 family.

219594:PDK4
gene id: 219594:PDK4
uniprot id: A0A6J3CPQ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PDK/BCKDK protein kinase family.
messages: Mitochondrion matrix

219594:PDE3A
gene id: 219594:PDE3A
uniprot id: A0A6J3DI07
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

219594:BMP6
gene id: 219594:BMP6
uniprot id: A0A6J3CDA1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TGF-beta family.
messages: Secreted

219594:UNKL
gene id: 219594:UNKL
uniprot id: A0A6J3DP09
uniprot id: A0A6J3DTA9
uniprot id: A0A6J3DUA9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the unkempt family.
messages: Cytoplasm

219594:PPP2R2A
gene id: 219594:PPP2R2A
uniprot id: A0A6J3E8E5
uniprot id: A0A6J3E9W4
uniprot id: A0A6J3ED32
uniprot id: A0A6J3EDH2
uniprot id: A0A6J3EF65
names: Similarity
messages: Belongs to the phosphatase 2A regulatory subunit B family.

219594:SLC12A8
gene id: 219594:SLC12A8
uniprot id: A0A6J3D9F9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC12A transporter family.
messages: Membrane

219594:MRPL43
gene id: 219594:MRPL43
uniprot id: A0A6J3D5X0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mL43 family.
messages: Mitochondrion

219594:STOML3
gene id: 219594:STOML3
uniprot id: A0A6J3EN68
names: Similarity
messages: Belongs to the band 7/mec-2 family.

219594:CNTF
gene id: 219594:CNTF
uniprot id: A0A6J3CYF2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CNTF family.
messages: CNTF is a survival factor for various neuronal cell types. Seems to prevent the degeneration of motor axons after axotomy.
messages: Cytoplasm

219594:EBF2
gene id: 219594:EBF2
uniprot id: A0A6J3E9Y1
uniprot id: A0A6J3ED55
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COE family.
messages: Nucleus

219594:PTPN3
gene id: 219594:PTPN3
uniprot id: A0A6J3CKD5
uniprot id: A0A6J3CMC4
uniprot id: A0A6J3CNT4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class subfamily.
messages: cytoskeleton

219594:EIF2B5
gene id: 219594:EIF2B5
uniprot id: A0A6J3DHW7
names: Similarity
messages: Belongs to the eIF-2B gamma/epsilon subunits family.

219594:SLC5A3
gene id: 219594:SLC5A3
uniprot id: A0A6J3CHB3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

219594:COPG2
gene id: 219594:COPG2
uniprot id: A0A6J3DI91
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the COPG family.
messages: COPI-coated vesicle membrane
messages: Cytoplasm
messages: Golgi apparatus membrane
messages: Membrane
messages: Oligomeric complex.
messages: The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.

219594:CKMT2
gene id: 219594:CKMT2
uniprot id: A0A6J3EG35
names: Similarity
messages: Belongs to the ATP:guanido phosphotransferase family.

219594:LOC116502376
gene id: 219594:LOC116502376
uniprot id: A0A6J3ELJ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone H3 family.
messages: Belongs to the histone H4 family.
messages: Chromosome
messages: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
messages: Nucleus

219594:RIOK2
gene id: 219594:RIOK2
uniprot id: A0A6J3EFF1
uniprot id: A0A6J3EKK8
names: Similarity
messages: Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family.

219594:SLC25A17
gene id: 219594:SLC25A17
uniprot id: A0A6J3DDA2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

219594:SUMF2
gene id: 219594:SUMF2
uniprot id: A0A6J3DZI5
uniprot id: A0A6J3E4M3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfatase-modifying factor family.
messages: Endoplasmic reticulum lumen

219594:EXTL2
gene id: 219594:EXTL2
uniprot id: A0A6J3DA18
uniprot id: A0A6J3DFT3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 47 family.
messages: Endoplasmic reticulum membrane

219594:GPR135
gene id: 219594:GPR135
uniprot id: A0A6J3CZG2
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

219594:NR0B2
gene id: 219594:NR0B2
uniprot id: A0A6J3E7X4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR0 subfamily.
messages: Cytoplasm
messages: Nucleus

219594:CELF1
gene id: 219594:CELF1
uniprot id: A0A6J3CY62
uniprot id: A0A6J3CY65
uniprot id: A0A6J3CY70
uniprot id: A0A6J3D0N8
uniprot id: A0A6J3D0P4
uniprot id: A0A6J3D0P7
uniprot id: A0A6J3D0Q9
uniprot id: A0A6J3D0R3
uniprot id: A0A6J3D0R8
uniprot id: A0A6J3D347
uniprot id: A0A6J3D351
uniprot id: A0A6J3D357
uniprot id: A0A6J3D473
uniprot id: A0A6J3D479
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CELF/BRUNOL family.
messages: Cytoplasm
messages: Nucleus

219594:NUDT7
gene id: 219594:NUDT7
uniprot id: A0A6J3DJJ5
uniprot id: A0A6J3DQ02
names: Similarity
messages: Belongs to the Nudix hydrolase family. PCD1 subfamily.

219594:EEF1AKMT1
gene id: 219594:EEF1AKMT1
uniprot id: A0A6J3DMZ5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. EFM5 family.
messages: Cytoplasm
messages: Protein-lysine methyltransferase that selectively catalyzes the trimethylation of EEF1A at 'Lys-79'.
messages: Was originally thought to be an N(6)-adenine-specific DNA methyltransferase based on primary sequence and predicted secondary structure.

219594:LOC116495867
gene id: 219594:LOC116495867
uniprot id: A0A6J3DXT8
names: Cofactor
names: Similarity
messages: Belongs to the transglutaminase superfamily. Transglutaminase family.
messages: Binds 1 Ca(2+) ion per subunit.

219594:ALG13
gene id: 219594:ALG13
uniprot id: A0A6J3DR55
names: Similarity
messages: Belongs to the glycosyltransferase 28 family.

219594:CLCN6
gene id: 219594:CLCN6
uniprot id: A0A6J3E532
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chloride channel (TC 2.A.49) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

219594:GLA
gene id: 219594:GLA
uniprot id: A0A6J3DQR1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycosyl hydrolase 27 family.
messages: Homodimer.
messages: Lysosome

219594:TAFA3
gene id: 219594:TAFA3
uniprot id: A0A6J3E6B8
names: Similarity
messages: Belongs to the TAFA family.

219594:ABCA12
gene id: 219594:ABCA12
uniprot id: A0A6J3D4B7
names: Subcellular Location Annotation
messages: Membrane

219594:ENPP1
gene id: 219594:ENPP1
uniprot id: A0A6J3CMW0
names: Subcellular Location Annotation
messages: Secreted

219594:TUBB4B
gene id: 219594:TUBB4B
uniprot id: A0A6J3E2L8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.
messages: cytoskeleton

219594:IRF4
gene id: 219594:IRF4
uniprot id: A0A6J3CJ93
names: Subcellular Location Annotation
messages: Nucleus

219594:SCARF1
gene id: 219594:SCARF1
uniprot id: A0A6J3E1F1
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:IDI1
gene id: 219594:IDI1
uniprot id: A0A6J3CIK6
names: Function
names: Similarity
messages: Belongs to the IPP isomerase type 1 family.
messages: Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP).

219594:PKN2
gene id: 219594:PKN2
uniprot id: A0A6J3D9H7
uniprot id: A0A6J3DD53
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.
messages: Cleavage furrow
messages: Midbody
messages: Nucleus

219594:PRDM1
gene id: 219594:PRDM1
uniprot id: A0A6J3CT42
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class V-like SAM-binding methyltransferase superfamily.
messages: Cytoplasm
messages: Interacts with PRMT5. Interacts with FBXO10. Interacts with FBXO11.
messages: Nucleus
messages: Transcription factor that mediates a transcriptional program in various innate and adaptive immune tissue-resident lymphocyte T cell types such as tissue-resident memory T (Trm), natural killer (trNK) and natural killer T (NKT) cells and negatively regulates gene expression of proteins that promote the egress of tissue-resident T-cell populations from non-lymphoid organs. Plays a role in the development, retention and long-term establishment of adaptive and innate tissue-resident lymphocyte T cell types in non-lymphoid organs, such as the skin and gut, but also in other nonbarrier tissues like liver and kidney, and therefore may provide immediate immunological protection against reactivating infections or viral reinfection. Binds specifically to the PRDI element in the promoter of the beta-interferon gene. Drives the maturation of B-lymphocytes into Ig secreting cells. Associates with the transcriptional repressor ZNF683 to chromatin at gene promoter regions.

219594:MPZ
gene id: 219594:MPZ
uniprot id: A0A6J3EB09
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the myelin P0 protein family.
messages: Cell membrane
messages: Is an adhesion molecule necessary for normal myelination in the peripheral nervous system. It mediates adhesion between adjacent myelin wraps and ultimately drives myelin compaction.
messages: Membrane

219594:DDIAS
gene id: 219594:DDIAS
uniprot id: A0A6J3EQP7
names: Similarity
messages: Belongs to the replication factor A protein 1 family.

219594:MARCHF4
gene id: 219594:MARCHF4
uniprot id: A0A6J3D9Y7
names: Subcellular Location Annotation
messages: Membrane

219594:CCDC153
gene id: 219594:CCDC153
uniprot id: A0A6J3E6C0
names: Similarity
messages: Belongs to the UPF0610 family.

219594:LOC116493524
gene id: 219594:LOC116493524
uniprot id: A0A6J3DNH5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

219594:ETV4
gene id: 219594:ETV4
uniprot id: A0A6J3E4T9
uniprot id: A0A6J3E977
uniprot id: A0A6J3E9U7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

219594:NR1H3
gene id: 219594:NR1H3
uniprot id: A0A6J3D1V5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR1 subfamily.
messages: Nucleus

219594:EIF4G1
gene id: 219594:EIF4G1
uniprot id: A0A6J3DFN4
names: Similarity
messages: Belongs to the eukaryotic initiation factor 4G family.

219594:TLX3
gene id: 219594:TLX3
uniprot id: A0A6J3DSY6
names: Subcellular Location Annotation
messages: Nucleus

219594:CDH10
gene id: 219594:CDH10
uniprot id: A0A6J3CGF0
uniprot id: A0A6J3CHD6
names: Function
names: Subcellular Location Annotation
messages: Cadherins are calcium-dependent cell adhesion proteins.
messages: Cell membrane

219594:RIPK2
gene id: 219594:RIPK2
uniprot id: A0A6J3CJI6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family.
messages: Cytoplasm
messages: Found in a signaling complex consisting of at least ARHGEF2, NOD2 and RIPK2.
messages: Serine/threonine/tyrosine-protein kinase that plays an essential role in modulation of innate and adaptive immune responses. Acts as a key effector of NOD1 and NOD2 signaling pathways: upon activation by bacterial peptidoglycans, NOD1 and NOD2 oligomerize and recruit RIPK2 via CARD-CARD domains, leading to the formation of RIPK2 filaments.

219594:PABPC1
gene id: 219594:PABPC1
uniprot id: A0A6J3CF35
uniprot id: A0A6J3CGR1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyadenylate-binding protein type-1 family.
messages: Binds the poly(A) tail of mRNA.
messages: Cytoplasm

219594:GGA2
gene id: 219594:GGA2
uniprot id: A0A6J3DX96
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GGA protein family.
messages: Early endosome membrane
messages: Endosome membrane
messages: Membrane
messages: trans-Golgi network membrane

219594:PIWIL2
gene id: 219594:PIWIL2
uniprot id: A0A6J3EDB5
names: Similarity
messages: Belongs to the argonaute family.

219594:BCOR
gene id: 219594:BCOR
uniprot id: A0A6J3EHK8
uniprot id: A0A6J3EHL7
uniprot id: A0A6J3EMV7
uniprot id: A0A6J3EMW3
uniprot id: A0A6J3EP67
names: Similarity
messages: Belongs to the BCOR family.

219594:EGR3
gene id: 219594:EGR3
uniprot id: A0A6J3EDA7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EGR C2H2-type zinc-finger protein family.
messages: Nucleus

219594:CLK4
gene id: 219594:CLK4
uniprot id: A0A6J3DSY3
uniprot id: A0A6J3DTZ4
names: Similarity
messages: Belongs to the protein kinase superfamily.

219594:TRMT61A
gene id: 219594:TRMT61A
uniprot id: A0A6J3D736
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TRM61 family.
messages: Catalytic subunit of tRNA (adenine-N(1)-)-methyltransferase, which catalyzes the formation of N(1)-methyladenine at position 58 (m1A58) in initiator methionyl-tRNA.
messages: Nucleus

219594:NBR1
gene id: 219594:NBR1
uniprot id: A0A6J3EAZ1
names: Subcellular Location Annotation
messages: autophagosome

219594:PRPF4
gene id: 219594:PRPF4
uniprot id: A0A6J3DZ11
names: Subcellular Location Annotation
messages: Nucleus speckle

219594:GTF2E2
gene id: 219594:GTF2E2
uniprot id: A0A6J3CTG4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TFIIE beta subunit family.
messages: Nucleus
messages: Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase.
messages: Tetramer of two alpha and two beta chains.

219594:FAM189B
gene id: 219594:FAM189B
uniprot id: A0A6J3EBD7
uniprot id: A0A6J3EGQ9
names: Similarity
messages: Belongs to the ENTREP family.

219594:WNK1
gene id: 219594:WNK1
uniprot id: A0A6J3D9X6
uniprot id: A0A6J3DA19
uniprot id: A0A6J3DAQ8
uniprot id: A0A6J3DAU4
uniprot id: A0A6J3DAV1
uniprot id: A0A6J3DCV2
uniprot id: A0A6J3DD72
uniprot id: A0A6J3DD93
uniprot id: A0A6J3DDC1
uniprot id: A0A6J3DDC7
names: Similarity
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.

219594:HDAC9
gene id: 219594:HDAC9
uniprot id: A0A6J3CFA0
uniprot id: A0A6J3CLI6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone deacetylase family. HD type 2 subfamily.
messages: Nucleus
messages: Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.

219594:NKX2-1
gene id: 219594:NKX2-1
uniprot id: A0A6J3D7N7
names: Subcellular Location Annotation
messages: Nucleus

219594:RPA2
gene id: 219594:RPA2
uniprot id: A0A6J3E571
names: Similarity
messages: Belongs to the replication factor A protein 2 family.

219594:FOXQ1
gene id: 219594:FOXQ1
uniprot id: A0A6J3CJK0
names: Subcellular Location Annotation
messages: Nucleus

219594:LOC116501065
gene id: 219594:LOC116501065
uniprot id: A0A6J3EGI2
names: Similarity
messages: Belongs to the G-alpha family. G(q) subfamily.

219594:CTBS
gene id: 219594:CTBS
uniprot id: A0A6J3D9D4
uniprot id: A0A6J3DF42
uniprot id: A0A6J3DF85
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 18 family.
messages: Lysosome

219594:LOC116500626
gene id: 219594:LOC116500626
uniprot id: A0A6J3EEI9
names: Cofactor
names: Function
names: Subunit
messages: Binds 1 zinc ion per subunit.
messages: Homotetramer.
messages: Involved in the regulation of homocysteine metabolism.

219594:HCN3
gene id: 219594:HCN3
uniprot id: A0A6J3EGW3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the potassium channel HCN family.
messages: Cell membrane
messages: Membrane

219594:SEPTIN3
gene id: 219594:SEPTIN3
uniprot id: A0A6J3DPC5
uniprot id: A0A6J3DPD6
uniprot id: A0A6J3DS95
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.
messages: Cytoplasm

219594:FERMT2
gene id: 219594:FERMT2
uniprot id: A0A6J3D1I3
uniprot id: A0A6J3D1K9
uniprot id: A0A6J3D411
uniprot id: A0A6J3D509
names: Similarity
messages: Belongs to the kindlin family.

219594:INO80C
gene id: 219594:INO80C
uniprot id: A0A6J3CMX0
names: Subcellular Location Annotation
messages: Nucleus

219594:LOC116492052
gene id: 219594:LOC116492052
uniprot id: A0A6J3DCX4
names: Similarity
messages: Belongs to the CLCR family.

219594:LOC116491544
gene id: 219594:LOC116491544
uniprot id: A0A6J3DB97
names: Subcellular Location Annotation
messages: Membrane

219594:FZR1
gene id: 219594:FZR1
uniprot id: A0A6J3E953
names: Similarity
messages: Belongs to the WD repeat CDC20/Fizzy family.

219594:VSX2
gene id: 219594:VSX2
uniprot id: A0A6J3D1F7
names: Subcellular Location Annotation
messages: Nucleus

219594:LOC116499687
gene id: 219594:LOC116499687
uniprot id: A0A6J3E9M0
uniprot id: A0A6J3EEQ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SCAMP family.
messages: Membrane

219594:SLC25A16
gene id: 219594:SLC25A16
uniprot id: A0A6J3DAX2
uniprot id: A0A6J3DBE6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

219594:DOCK9
gene id: 219594:DOCK9
uniprot id: A0A6J3CGE7
uniprot id: A0A6J3CGI2
uniprot id: A0A6J3CGJ4
uniprot id: A0A6J3CGK4
uniprot id: A0A6J3CGP6
uniprot id: A0A6J3CGQ6
uniprot id: A0A6J3CI60
uniprot id: A0A6J3CI74
uniprot id: A0A6J3CIA9
uniprot id: A0A6J3CIC3
uniprot id: A0A6J3CJ21
uniprot id: A0A6J3CJ32
uniprot id: A0A6J3CJD5
uniprot id: A0A6J3CLB0
uniprot id: A0A6J3CLC7
uniprot id: A0A6J3CMP5
uniprot id: A0A6J3CMT9
names: Similarity
messages: Belongs to the DOCK family.

219594:QPCT
gene id: 219594:QPCT
uniprot id: A0A6J3CR75
uniprot id: A0A6J3CXD6
names: Similarity
messages: Belongs to the glutaminyl-peptide cyclotransferase family.

219594:TMOD1
gene id: 219594:TMOD1
uniprot id: A0A6J3EKH4
uniprot id: A0A6J3EM15
names: Subcellular Location Annotation
messages: cytoskeleton

219594:AGPAT5
gene id: 219594:AGPAT5
uniprot id: A0A6J3CLX6
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.

219594:GABRB3
gene id: 219594:GABRB3
uniprot id: A0A6J3CSV9
uniprot id: A0A6J3CVN2
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

219594:PDPK1
gene id: 219594:PDPK1
uniprot id: A0A6J3DSG4
uniprot id: A0A6J3DWB5
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PDPK1 subfamily.

219594:PARVA
gene id: 219594:PARVA
uniprot id: A0A6J3CZ39
uniprot id: A0A6J3CZE2
uniprot id: A0A6J3D1N6
uniprot id: A0A6J3D2S6
names: Similarity
messages: Belongs to the parvin family.

219594:NEU2
gene id: 219594:NEU2
uniprot id: A0A6J3DF22
names: Similarity
messages: Belongs to the glycosyl hydrolase 33 family.

219594:RAX2
gene id: 219594:RAX2
uniprot id: A0A6J3EEN9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the paired homeobox family. Bicoid subfamily.
messages: Nucleus

219594:PPRC1
gene id: 219594:PPRC1
uniprot id: A0A6J3D6Q5
names: Subcellular Location Annotation
messages: Nucleus

219594:LOC116491310
gene id: 219594:LOC116491310
uniprot id: A0A6J3D9Z7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the beta-microseminoprotein family.
messages: Secreted

219594:HYAL3
gene id: 219594:HYAL3
uniprot id: A0A6J3DLA4
names: Similarity
messages: Belongs to the glycosyl hydrolase 56 family.

219594:SCN2A
gene id: 219594:SCN2A
uniprot id: A0A6J3D495
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium channel (TC 1.A.1.10) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient.
messages: Membrane

219594:LOC116489415
gene id: 219594:LOC116489415
uniprot id: A0A6J3D358
names: Similarity
messages: Belongs to the CD225/Dispanin family.

219594:LOC116493700
gene id: 219594:LOC116493700
uniprot id: A0A6J3DKP9
uniprot id: A0A6J3DNM1
uniprot id: A0A6J3DP90
names: Subcellular Location Annotation
messages: Cytoplasm

219594:HBEGF
gene id: 219594:HBEGF
uniprot id: A0A6J3DMU2
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:NCOR1
gene id: 219594:NCOR1
uniprot id: A0A6J3E3C2
uniprot id: A0A6J3E453
uniprot id: A0A6J3E459
names: Similarity
messages: Belongs to the N-CoR nuclear receptor corepressors family.

219594:LOC116491423
gene id: 219594:LOC116491423
uniprot id: A0A6J3D737
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UDP-glycosyltransferase family.
messages: Membrane

219594:LCA5L
gene id: 219594:LCA5L
uniprot id: A0A6J3D643
names: Similarity
messages: Belongs to the LCA5 family.

219594:C1H12orf57
gene id: 219594:C1H12orf57
uniprot id: A0A6J3EAM1
uniprot id: A0A6J3EB71
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0456 family.
messages: Cytoplasm

219594:ARHGAP32
gene id: 219594:ARHGAP32
uniprot id: A0A6J3E295
uniprot id: A0A6J3E3N1
uniprot id: A0A6J3E6I6
uniprot id: A0A6J3E8J6
names: Similarity
messages: Belongs to the PX domain-containing GAP family.

219594:PAX3
gene id: 219594:PAX3
uniprot id: A0A6J3DCK2
uniprot id: A0A6J3DF97
uniprot id: A0A6J3DI39
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the paired homeobox family.
messages: Nucleus

219594:CDCP2
gene id: 219594:CDCP2
uniprot id: A0A6J3D9K5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:MCTS1
gene id: 219594:MCTS1
uniprot id: A0A6J3DS04
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MCTS1 family.
messages: Cytoplasm

219594:HM13
gene id: 219594:HM13
uniprot id: A0A6J3DT04
uniprot id: A0A6J3DX75
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A22B family.
messages: Membrane

219594:NCAN
gene id: 219594:NCAN
uniprot id: A0A6J3E986
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:PLN
gene id: 219594:PLN
uniprot id: A0A6J3CRC1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phospholamban family.
messages: Endoplasmic reticulum membrane
messages: Homopentamer.
messages: Membrane
messages: Mitochondrion membrane
messages: Reversibly inhibits the activity of ATP2A2 in cardiac sarcoplasmic reticulum by decreasing the apparent affinity of the ATPase for Ca(2+). Modulates the contractility of the heart muscle in response to physiological stimuli via its effects on ATP2A2. Modulates calcium re-uptake during muscle relaxation and plays an important role in calcium homeostasis in the heart muscle. The degree of ATP2A2 inhibition depends on the oligomeric state of PLN.
messages: Sarcoplasmic reticulum membrane

219594:ITGAE
gene id: 219594:ITGAE
uniprot id: A0A6J3E008
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin alpha chain family.
messages: Membrane

219594:CPSF7
gene id: 219594:CPSF7
uniprot id: A0A6J3D6Y0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRM CPSF6/7 family.
messages: Nucleus

219594:ARHGEF11
gene id: 219594:ARHGEF11
uniprot id: A0A6J3EEG0
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Membrane

219594:SMAGP
gene id: 219594:SMAGP
uniprot id: A0A6J3EAT0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SMAGP family.
messages: Cell membrane
messages: Cytoplasmic vesicle membrane
messages: Membrane

219594:LOC116492742
gene id: 219594:LOC116492742
uniprot id: A0A6J3DHK4
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the alkaline phosphatase family.
messages: Binds 1 Mg(2+) ion.
messages: Binds 2 Zn(2+) ions.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

219594:CKB
gene id: 219594:CKB
uniprot id: A0A6J3D0X9
uniprot id: A0A6J3D107
names: Similarity
messages: Belongs to the ATP:guanido phosphotransferase family.

219594:ID2
gene id: 219594:ID2
uniprot id: A0A6J3CQF6
names: Subcellular Location Annotation
messages: Nucleus

219594:MAEL
gene id: 219594:MAEL
uniprot id: A0A6J3ENP1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the maelstrom family.
messages: Nucleus
messages: Plays a central role during spermatogenesis by repressing transposable elements and preventing their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposons. Its association with piP-bodies suggests a participation in the secondary piRNAs metabolic process. Required for the localization of germ-cell factors to the meiotic nuage.

219594:VDAC2
gene id: 219594:VDAC2
uniprot id: A0A6J3D622
uniprot id: A0A6J3D9A4
names: Similarity
messages: Belongs to the eukaryotic mitochondrial porin family.

219594:TPST1
gene id: 219594:TPST1
uniprot id: A0A6J3E4K0
uniprot id: A0A6J3E4L2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein sulfotransferase family.
messages: Catalyzes the O-sulfation of tyrosine residues within acidic motifs of polypeptides, using 3'-phosphoadenylyl sulfate (PAPS) as cosubstrate.
messages: Golgi apparatus membrane

219594:EHD4
gene id: 219594:EHD4
uniprot id: A0A6J3CYN9
names: Subcellular Location Annotation
messages: Cell membrane
messages: Endosome membrane
messages: Membrane

219594:PDCL3
gene id: 219594:PDCL3
uniprot id: A0A6J3DTK1
names: Similarity
messages: Belongs to the phosducin family.

219594:FOXD3
gene id: 219594:FOXD3
uniprot id: A0A6J3DC69
names: Subcellular Location Annotation
messages: Nucleus

219594:LOC116500328
gene id: 219594:LOC116500328
uniprot id: A0A6J3EIE1
names: Subcellular Location Annotation
messages: Membrane

219594:DDX1
gene id: 219594:DDX1
uniprot id: A0A6J3CT12
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DEAD box helicase family. DDX1 subfamily.
messages: Cytoplasmic granule
messages: RNA helicase.
messages: The helicase domain is involved in the stimulation of RELA transcriptional activity.

219594:MYD88
gene id: 219594:MYD88
uniprot id: A0A6J3CM88
names: Function
names: Subcellular Location Annotation
messages: Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response.
messages: Cytoplasm

219594:ABAT
gene id: 219594:ABAT
uniprot id: A0A6J3DRU4
names: Similarity
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer; disulfide-linked.

219594:RAB21
gene id: 219594:RAB21
uniprot id: A0A6J3EPH5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Cleavage furrow
messages: Early endosome membrane
messages: Endoplasmic reticulum membrane
messages: trans-Golgi network

219594:NIF3L1
gene id: 219594:NIF3L1
uniprot id: A0A6J3D2B1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.
messages: Cytoplasm
messages: Homodimer. Interacts with COPS2. Interacts with THOC7.
messages: May function as a transcriptional corepressor through its interaction with COPS2, negatively regulating the expression of genes involved in neuronal differentiation.
messages: Nucleus

219594:GPSM2
gene id: 219594:GPSM2
uniprot id: A0A6J3DGI3
names: Similarity
messages: Belongs to the GPSM family.

219594:CACNB4
gene id: 219594:CACNB4
uniprot id: A0A6J3D2S0
uniprot id: A0A6J3D5K8
uniprot id: A0A6J3D7U1
uniprot id: A0A6J3D8M5
names: Similarity
messages: Belongs to the calcium channel beta subunit family.

219594:ATP5MF
gene id: 219594:ATP5MF
uniprot id: A0A6J3DTN8
names: Function
names: Similarity
messages: Belongs to the ATPase F chain family.
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain. Minor subunit located with subunit a in the membrane.

219594:LOC116501319
gene id: 219594:LOC116501319
uniprot id: A0A6J3EHN3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

219594:CCNT1
gene id: 219594:CCNT1
uniprot id: A0A6J3EBU1
names: Similarity
messages: Belongs to the cyclin family.

219594:SLC6A11
gene id: 219594:SLC6A11
uniprot id: A0A6J3DIQ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

219594:STX12
gene id: 219594:STX12
uniprot id: A0A6J3E896
names: Similarity
messages: Belongs to the syntaxin family.

219594:LOC116499453
gene id: 219594:LOC116499453
uniprot id: A0A6J3EA63
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IL-1 family.
messages: Secreted

219594:EPB41
gene id: 219594:EPB41
uniprot id: A0A6J3E3C6
uniprot id: A0A6J3E3C9
uniprot id: A0A6J3E3D4
uniprot id: A0A6J3E3D9
uniprot id: A0A6J3E3E4
uniprot id: A0A6J3E4R5
uniprot id: A0A6J3E4S0
uniprot id: A0A6J3E4S6
uniprot id: A0A6J3E4T0
uniprot id: A0A6J3E4U2
uniprot id: A0A6J3E7N7
uniprot id: A0A6J3E7P2
uniprot id: A0A6J3E7P5
uniprot id: A0A6J3E7Q0
uniprot id: A0A6J3E7Q5
uniprot id: A0A6J3E8B0
uniprot id: A0A6J3E8B5
uniprot id: A0A6J3E8C0
uniprot id: A0A6J3E8C4
uniprot id: A0A6J3E8C9
uniprot id: A0A6J3E8D2
uniprot id: A0A6J3E9Q6
uniprot id: A0A6J3E9R1
uniprot id: A0A6J3E9R5
uniprot id: A0A6J3E9S1
uniprot id: A0A6J3E9S6
uniprot id: A0A6J3E9T2
names: Subcellular Location Annotation
messages: Nucleus
messages: cell cortex
messages: cytoskeleton

219594:GLYR1
gene id: 219594:GLYR1
uniprot id: A0A6J3DP84
uniprot id: A0A6J3DUH8
uniprot id: A0A6J3DVC0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HIBADH-related family. NP60 subfamily.
messages: Chromosome

219594:PI4KA
gene id: 219594:PI4KA
uniprot id: A0A6J3DZE9
names: Similarity
messages: Belongs to the PI3/PI4-kinase family. Type III PI4K subfamily.

219594:LOC116498495
gene id: 219594:LOC116498495
uniprot id: A0A6J3E9A8
uniprot id: A0A6J3EA26
uniprot id: A0A6J3EBC7
uniprot id: A0A6J3EBG3
names: Similarity
messages: Belongs to the sulfatase family.

219594:CDH8
gene id: 219594:CDH8
uniprot id: A0A6J3DMI9
uniprot id: A0A6J3DPI0
names: Function
names: Subcellular Location Annotation
messages: Cadherins are calcium-dependent cell adhesion proteins.
messages: Cell membrane

219594:CSMD1
gene id: 219594:CSMD1
uniprot id: A0A6J3CNN0
uniprot id: A0A6J3CQL6
uniprot id: A0A6J3CTK2
uniprot id: A0A6J3CUQ1
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:TENT5B
gene id: 219594:TENT5B
uniprot id: A0A6J3EAF1
names: Similarity
messages: Belongs to the TENT family.

219594:TRPC3
gene id: 219594:TRPC3
uniprot id: A0A6J3D1L2
names: Subcellular Location Annotation
messages: Membrane

219594:ND2
gene id: 219594:ND2
uniprot id: A0A068L8T3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 2 family.
messages: Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor. Essential for the catalytic activity and assembly of complex I.
messages: Membrane
messages: Mitochondrion inner membrane

219594:TMED6
gene id: 219594:TMED6
uniprot id: A0A6J3DIG3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EMP24/GP25L family.
messages: Endoplasmic reticulum membrane
messages: Membrane

219594:LOC116489887
gene id: 219594:LOC116489887
uniprot id: A0A6J3CZP0
names: Domain
names: Subcellular Location Annotation
messages: The N-terminal C2 domain associates with lipid membranes upon calcium binding.
messages: cytosol

219594:LOC116488304
gene id: 219594:LOC116488304
uniprot id: A0A6J3CXM7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily.
messages: Membrane

219594:AIF1L
gene id: 219594:AIF1L
uniprot id: A0A6J3DZF2
names: Subcellular Location Annotation
messages: ruffle membrane

219594:LOC116499871
gene id: 219594:LOC116499871
uniprot id: A0A6J3EH01
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

219594:WASF1
gene id: 219594:WASF1
uniprot id: A0A6J3CW82
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SCAR/WAVE family.
messages: Binds actin and the Arp2/3 complex.
messages: Downstream effector molecule involved in the transmission of signals from tyrosine kinase receptors and small GTPases to the actin cytoskeleton. Promotes formation of actin filaments. Part of the WAVE complex that regulates lamellipodia formation. The WAVE complex regulates actin filament reorganization via its interaction with the Arp2/3 complex.
messages: cytoskeleton

219594:RFC1
gene id: 219594:RFC1
uniprot id: A0A6J3CYD0
uniprot id: A0A6J3CYP8
uniprot id: A0A6J3D235
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the activator 1 large subunit family.
messages: Nucleus

219594:LOC116492644
gene id: 219594:LOC116492644
uniprot id: A0A6J3DD28
uniprot id: A0A6J3DIM1
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

219594:RIMKLB
gene id: 219594:RIMKLB
uniprot id: A0A6J3D475
names: Similarity
messages: Belongs to the RimK family.

219594:LOC116495782
gene id: 219594:LOC116495782
uniprot id: A0A6J3DUK9
names: Subcellular Location Annotation
messages: Membrane

219594:EAF1
gene id: 219594:EAF1
uniprot id: A0A6J3CI66
names: Similarity
messages: Belongs to the EAF family.

219594:LHPP
gene id: 219594:LHPP
uniprot id: A0A6J3DDC2
uniprot id: A0A6J3DDP6
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.

219594:ZNF280D
gene id: 219594:ZNF280D
uniprot id: A0A6J3DIT0
uniprot id: A0A6J3DIT5
uniprot id: A0A6J3DLN4
uniprot id: A0A6J3DLN9
uniprot id: A0A6J3DM55
uniprot id: A0A6J3DM60
names: Function
names: Subcellular Location Annotation
messages: May function as a transcription factor.
messages: Nucleus

219594:FES
gene id: 219594:FES
uniprot id: A0A6J3DHJ3
uniprot id: A0A6J3DK45
uniprot id: A0A6J3DLL5
uniprot id: A0A6J3DNM5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. Fes/fps subfamily.
messages: cytoskeleton

219594:GGA3
gene id: 219594:GGA3
uniprot id: A0A6J3DXG2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GGA protein family.
messages: Early endosome membrane
messages: Endosome membrane
messages: Membrane
messages: trans-Golgi network membrane

219594:CDA
gene id: 219594:CDA
uniprot id: A0A6J3E621
names: Function
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.

219594:PPM1G
gene id: 219594:PPM1G
uniprot id: A0A6J3CUI7
names: Similarity
messages: Belongs to the PP2C family.

219594:WDR82
gene id: 219594:WDR82
uniprot id: A0A6J3DKM7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat SWD2 family.
messages: Nucleus

219594:LOC116497037
gene id: 219594:LOC116497037
uniprot id: A0A6J3E2R3
names: Similarity
messages: Belongs to the GDA1/CD39 NTPase family.

219594:NBN
gene id: 219594:NBN
uniprot id: A0A6J3CP87
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Component of the MRE11-RAD50-NBN (MRN complex) which plays a critical role in the cellular response to DNA damage and the maintenance of chromosome integrity. The complex is involved in double-strand break (DSB) repair, DNA recombination, maintenance of telomere integrity, cell cycle checkpoint control and meiosis.
messages: Component of the MRN complex.
messages: Nucleus
messages: telomere

219594:CDCA7L
gene id: 219594:CDCA7L
uniprot id: A0A6J3CFM5
uniprot id: A0A6J3CI98
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

219594:NEMP1
gene id: 219594:NEMP1
uniprot id: A0A6J3EF07
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NEMP family.
messages: Nucleus inner membrane

219594:LOC116498533
gene id: 219594:LOC116498533
uniprot id: A0A6J3EBH6
names: Similarity
names: Subunit
messages: Belongs to the avian keratin family.
messages: The avian keratins (F-ker, S-ker, C-ker and B-ker) are a complex mixture of very similar polypeptides.

219594:PPP1R1C
gene id: 219594:PPP1R1C
uniprot id: A0A6J3D706
names: Similarity
messages: Belongs to the protein phosphatase inhibitor 1 family.

219594:FAM149A
gene id: 219594:FAM149A
uniprot id: A0A6J3CUX3
names: Similarity
messages: Belongs to the FAM149 family.

219594:LOC116502365
gene id: 219594:LOC116502365
uniprot id: A0A6J3ES04
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2B family.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

219594:NSA2
gene id: 219594:NSA2
uniprot id: A0A6J3ECV0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eS8 family. Ribosome biogenesis protein NSA2 subfamily.
messages: Component of the pre-66S ribosomal particle.
messages: Involved in the biogenesis of the 60S ribosomal subunit. May play a part in the quality control of pre-60S particles.
messages: nucleolus

219594:CTSA
gene id: 219594:CTSA
uniprot id: A0A6J3DWT6
names: Similarity
messages: Belongs to the peptidase S10 family.

219594:RRAD
gene id: 219594:RRAD
uniprot id: A0A6J3DN91
names: Similarity
messages: Belongs to the small GTPase superfamily. RGK family.

219594:PDS5A
gene id: 219594:PDS5A
uniprot id: A0A6J3CTC7
uniprot id: A0A6J3CVN9
uniprot id: A0A6J3CW45
names: Subcellular Location Annotation
messages: Nucleus

219594:CENPT
gene id: 219594:CENPT
uniprot id: A0A6J3DIZ1
uniprot id: A0A6J3DN44
uniprot id: A0A6J3DPE6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CENP-T/CNN1 family.
messages: Nucleus
messages: kinetochore

219594:KIF20B
gene id: 219594:KIF20B
uniprot id: A0A6J3DAM9
uniprot id: A0A6J3DDJ4
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

219594:MYOZ2
gene id: 219594:MYOZ2
uniprot id: A0A6J3D0T1
names: Similarity
messages: Belongs to the myozenin family.

219594:BDNF
gene id: 219594:BDNF
uniprot id: A0A6J3D0W6
uniprot id: A0A6J3D5U0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NGF-beta family.
messages: Promotes the survival of neuronal populations that are all located either in the central nervous system or directly connected to it.
messages: Secreted

219594:UBA2
gene id: 219594:UBA2
uniprot id: A0A6J3DPC8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ubiquitin-activating E1 family.
messages: Heterodimer of SAE1 and UBA2/SAE2. The heterodimer corresponds to the two domains that are encoded on a single polypeptide chain in ubiquitin-activating enzyme E1. Interacts with UBE2I.
messages: Nucleus
messages: The heterodimer acts as an E1 ligase for SUMO1, SUMO2, SUMO3, and probably SUMO4. It mediates ATP-dependent activation of SUMO proteins followed by formation of a thioester bond between a SUMO protein and a conserved active site cysteine residue on UBA2/SAE2.

219594:LOC116499408
gene id: 219594:LOC116499408
uniprot id: A0A6J3EA14
names: Similarity
messages: Belongs to the dynactin subunit 2 family.

219594:ATP5F1E
gene id: 219594:ATP5F1E
uniprot id: A0A6J3DX24
names: Function
names: Similarity
messages: Belongs to the eukaryotic ATPase epsilon family.
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(1) domain and of the central stalk which is part of the complex rotary element. Rotation of the central stalk against the surrounding alpha(3)beta(3) subunits leads to hydrolysis of ATP in three separate catalytic sites on the beta subunits.

219594:SEMA3G
gene id: 219594:SEMA3G
uniprot id: A0A6J3DI24
names: Caution
names: Similarity
messages: Belongs to the semaphorin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:NXPH4
gene id: 219594:NXPH4
uniprot id: A0A6J3EA98
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the neurexophilin family.
messages: Secreted

219594:AHCYL2
gene id: 219594:AHCYL2
uniprot id: A0A6J3E1X7
names: Cofactor
names: Similarity
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.

219594:LOC116493544
gene id: 219594:LOC116493544
uniprot id: A0A6J3DNJ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

219594:DPH1
gene id: 219594:DPH1
uniprot id: A0A6J3E4I1
names: Similarity
messages: Belongs to the DPH1/DPH2 family. DPH1 subfamily.

219594:KCNJ3
gene id: 219594:KCNJ3
uniprot id: A0A6J3D6B5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associates with GIRK2, GIRK3 or GIRK4 to form a G-protein activated heteromultimer pore-forming unit. The resulting inward current is much larger.
messages: Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family. KCNJ3 subfamily.
messages: Membrane
messages: This potassium channel is controlled by G proteins. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. This receptor plays a crucial role in regulating the heartbeat.

219594:LOC116494911
gene id: 219594:LOC116494911
uniprot id: A0A6J3DTF0
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: Potential calcium-dependent cell-adhesion protein. May be involved in the establishment and maintenance of specific neuronal connections in the brain.

219594:LOC116502306
gene id: 219594:LOC116502306
uniprot id: A0A6J3EL91
names: Subcellular Location Annotation
messages: Membrane

219594:ADCYAP1R1
gene id: 219594:ADCYAP1R1
uniprot id: A0A6J3CIE4
uniprot id: A0A6J3CJV1
uniprot id: A0A6J3CN03
uniprot id: A0A6J3CPF4
uniprot id: A0A6J3CPF9
names: Subcellular Location Annotation
messages: Membrane

219594:MUC4
gene id: 219594:MUC4
uniprot id: A0A6J3DHZ7
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:FAM187A
gene id: 219594:FAM187A
uniprot id: A0A6J3EAN9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAM187 family.
messages: Membrane

219594:FSIP1
gene id: 219594:FSIP1
uniprot id: A0A6J3CZ34
names: Similarity
messages: Belongs to the FSIP1 family.

219594:DCLRE1B
gene id: 219594:DCLRE1B
uniprot id: A0A6J3EBI3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA repair metallo-beta-lactamase (DRMBL) family.
messages: Nucleus

219594:LOC116488616
gene id: 219594:LOC116488616
uniprot id: A0A6J3CVB0
names: Subcellular Location Annotation
messages: Secreted

219594:RBBP8
gene id: 219594:RBBP8
uniprot id: A0A6J3CL36
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COM1/SAE2/CtIP family.
messages: Nucleus

219594:NME8
gene id: 219594:NME8
uniprot id: A0A6J3CFW7
names: Similarity
messages: Belongs to the NDK family.

219594:GNPTAB
gene id: 219594:GNPTAB
uniprot id: A0A6J3E6F3
uniprot id: A0A6J3E8H1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the stealth family.
messages: Membrane

219594:LOC116495307
gene id: 219594:LOC116495307
uniprot id: A0A6J3DUJ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome P450 family.
messages: Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.
messages: Endoplasmic reticulum membrane
messages: Microsome membrane

219594:TBC1D23
gene id: 219594:TBC1D23
uniprot id: A0A6J3DET6
uniprot id: A0A6J3DEU5
names: Subcellular Location Annotation
messages: trans-Golgi network

219594:NUDT4
gene id: 219594:NUDT4
uniprot id: A0A6J3D144
uniprot id: A0A6J3D4N7
names: Similarity
messages: Belongs to the Nudix hydrolase family. DIPP subfamily.

219594:EXOC3L1
gene id: 219594:EXOC3L1
uniprot id: A0A6J3DIF0
names: Similarity
messages: Belongs to the SEC6 family.

219594:TRIP13
gene id: 219594:TRIP13
uniprot id: A0A6J3CHZ4
uniprot id: A0A6J3CP28
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAA ATPase family. PCH2 subfamily.
messages: Nucleus
messages: Plays a key role in chromosome recombination and chromosome structure development during meiosis. Required at early steps in meiotic recombination that leads to non-crossovers pathways. Also needed for efficient completion of homologous synapsis by influencing crossover distribution along the chromosomes affecting both crossovers and non-crossovers pathways.

219594:LOC116490162
gene id: 219594:LOC116490162
uniprot id: A0A6J3D3H1
uniprot id: A0A6J3D623
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

219594:ACE2
gene id: 219594:ACE2
uniprot id: A0A6J3E419
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M2 family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Cytoplasm
messages: Membrane
messages: Secreted
messages: cilium

219594:TTYH2
gene id: 219594:TTYH2
uniprot id: A0A6J3DWV3
uniprot id: A0A6J3E119
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tweety family.
messages: Cell membrane
messages: Membrane
messages: Probable chloride channel.

219594:BMP3
gene id: 219594:BMP3
uniprot id: A0A6J3CXN8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TGF-beta family.
messages: Secreted

219594:SSH1
gene id: 219594:SSH1
uniprot id: A0A6J3DV75
uniprot id: A0A6J3DXF2
uniprot id: A0A6J3DZB3
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family.

219594:MRM1
gene id: 219594:MRM1
uniprot id: A0A6J3E6H3
names: Similarity
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.

219594:LOC116486878
gene id: 219594:LOC116486878
uniprot id: A0A6J3CJZ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Early endosome
messages: Endosome
messages: Membrane

219594:LOC116486620
gene id: 219594:LOC116486620
uniprot id: A0A6J3CPU8
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily.

219594:LOC116485437
gene id: 219594:LOC116485437
uniprot id: A0A6J3CIL5
names: Similarity
names: Subunit
messages: Belongs to the avian keratin family.
messages: The avian keratins (F-ker, S-ker, C-ker and B-ker) are a complex mixture of very similar polypeptides.

219594:DHX8
gene id: 219594:DHX8
uniprot id: A0A6J3EB92
names: Subcellular Location Annotation
messages: Nucleus

219594:PLTP
gene id: 219594:PLTP
uniprot id: A0A6J3DXY4
names: Similarity
messages: Belongs to the BPI/LBP/Plunc superfamily. BPI/LBP family.

219594:LOC116501058
gene id: 219594:LOC116501058
uniprot id: A0A6J3EF11
names: Similarity
messages: Belongs to the avidin/streptavidin family.

219594:MYBL1
gene id: 219594:MYBL1
uniprot id: A0A6J3CFZ5
uniprot id: A0A6J3CKJ6
uniprot id: A0A6J3CM89
names: Subcellular Location Annotation
messages: Nucleus

219594:RNGTT
gene id: 219594:RNGTT
uniprot id: A0A6J3CTC4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bifunctional mRNA-capping enzyme exhibiting RNA 5'-triphosphate monophosphatase activity in the N-terminal part and mRNA guanylyltransferase activity in the C-terminal part. Catalyzes the first two steps of cap formation: by removing the gamma-phosphate from the 5'-triphosphate end of nascent mRNA to yield a diphosphate end, and by transferring the GMP moiety of GTP to the 5'-diphosphate terminus of RNA via a covalent enzyme-GMP reaction intermediate.
messages: In the C-terminal section; belongs to the eukaryotic GTase family.
messages: In the N-terminal section; belongs to the non-receptor class of the protein-tyrosine phosphatase family.
messages: Nucleus

219594:LOC116492636
gene id: 219594:LOC116492636
uniprot id: A0A6J3DGY8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the reduced folate carrier (RFC) transporter (TC 2.A.48) family.
messages: Membrane

219594:LOC116502118
gene id: 219594:LOC116502118
uniprot id: A0A6J3EKF2
names: Similarity
messages: Belongs to the Arg-specific ADP-ribosyltransferase family.

219594:LOC116490905
gene id: 219594:LOC116490905
uniprot id: A0A6J3D7J3
names: Similarity
messages: Belongs to the cytochrome P450 family.

219594:GFRA2
gene id: 219594:GFRA2
uniprot id: A0A6J3EDP0
uniprot id: A0A6J3EFD5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GDNFR family.
messages: Cell membrane
messages: Membrane
messages: Receptor for neurturin. Mediates the NRTN-induced autophosphorylation and activation of the RET receptor. Also able to mediate GDNF signaling through the RET tyrosine kinase receptor.

219594:IBSP
gene id: 219594:IBSP
uniprot id: A0A6J3D1H0
names: Function
names: Subcellular Location Annotation
messages: Binds tightly to hydroxyapatite. Appears to form an integral part of the mineralized matrix. Probably important to cell-matrix interaction. Promotes Arg-Gly-Asp-dependent cell attachment.
messages: Secreted

219594:PHLDA2
gene id: 219594:PHLDA2
uniprot id: A0A6J3CZC8
names: Subcellular Location Annotation
messages: Cytoplasm

219594:LOC116485394
gene id: 219594:LOC116485394
uniprot id: A0A6J3CC62
names: Similarity
names: Subunit
messages: Belongs to the avian keratin family.
messages: The avian keratins (F-ker, S-ker, C-ker and B-ker) are a complex mixture of very similar polypeptides.

219594:GGACT
gene id: 219594:GGACT
uniprot id: A0A6J3CXF2
uniprot id: A0A6J3D3B0
names: Function
names: Similarity
messages: Belongs to the gamma-glutamylcyclotransferase family.
messages: Catalyzes the formation of 5-oxo-L-proline from L-gamma-glutamyl-L-epsilon-lysine.

219594:GCNT3
gene id: 219594:GCNT3
uniprot id: A0A6J3DI15
names: Subcellular Location Annotation
messages: Golgi apparatus membrane
messages: Membrane

219594:PATJ
gene id: 219594:PATJ
uniprot id: A0A6J3DEP1
names: Subcellular Location Annotation
messages: tight junction

219594:NOL12
gene id: 219594:NOL12
uniprot id: A0A6J3DFN7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRP17 family.
messages: nucleolus

219594:LOC116486268
gene id: 219594:LOC116486268
uniprot id: A0A6J3CLF8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G protein gamma family.
messages: Cell membrane
messages: G proteins are composed of 3 units; alpha, beta and gamma.
messages: Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.

219594:LOC116486660
gene id: 219594:LOC116486660
uniprot id: A0A6J3CKF7
names: Similarity
messages: Belongs to the TMEM14 family.

219594:LOC116492465
gene id: 219594:LOC116492465
uniprot id: A0A6J3DG77
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptobrevin family.
messages: Membrane

219594:RNF168
gene id: 219594:RNF168
uniprot id: A0A6J3DFM3
names: Caution
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNF168 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus
messages: The MIU motif (motif interacting with ubiquitin) mediates the interaction with both 'Lys-48'- and 'Lys-63'-linked ubiquitin chains. The UMI motif mediates interaction with ubiquitin with a preference for 'Lys-63'-linked ubiquitin. The specificity for different types of ubiquitin is mediated by juxtaposition of ubiquitin-binding motifs (MIU and UMI motifs) with LR motifs (LRMs).

219594:SGCG
gene id: 219594:SGCG
uniprot id: A0A6J3DVK9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sarcoglycan beta/delta/gamma/zeta family.
messages: cytoskeleton
messages: sarcolemma

219594:KCNF1
gene id: 219594:KCNF1
uniprot id: A0A6J3CW26
names: Subcellular Location Annotation
messages: Membrane

219594:CPT2
gene id: 219594:CPT2
uniprot id: A0A6J3DBQ3
names: Similarity
messages: Belongs to the carnitine/choline acetyltransferase family.

219594:CEP70
gene id: 219594:CEP70
uniprot id: A0A6J3D555
uniprot id: A0A6J3DB23
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Directly interacts with tubulin-gamma; this interaction determines centrosomal localization.
messages: Plays a role in the organization of both preexisting and nascent microtubules in interphase cells. During mitosis, required for the organization and orientation of the mitotic spindle.
messages: centrosome

219594:RPS25
gene id: 219594:RPS25
uniprot id: A0A6J3E3R8
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eS25 family.
messages: Component of the small ribosomal subunit.

219594:PABPC1L
gene id: 219594:PABPC1L
uniprot id: A0A6J3DYZ8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyadenylate-binding protein type-1 family.
messages: Binds the poly(A) tail of mRNA.
messages: Cytoplasm

219594:TMEM54
gene id: 219594:TMEM54
uniprot id: A0A6J3E8E4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM54 family.
messages: Membrane

219594:TMED1
gene id: 219594:TMED1
uniprot id: A0A6J3EHL2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EMP24/GP25L family.
messages: Endoplasmic reticulum membrane
messages: Endoplasmic reticulum-Golgi intermediate compartment membrane
messages: Membrane
messages: cis-Golgi network membrane

219594:LOC116498201
gene id: 219594:LOC116498201
uniprot id: A0A6J3E3Z3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the E2F/DP family.
messages: Nucleus

219594:DHX30
gene id: 219594:DHX30
uniprot id: A0A6J3CK80
uniprot id: A0A6J3CLG0
uniprot id: A0A6J3CND8
names: Similarity
messages: Belongs to the DEAD box helicase family. DEAH subfamily.

219594:LOC116500021
gene id: 219594:LOC116500021
uniprot id: A0A6J3EAU5
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

219594:AP4B1
gene id: 219594:AP4B1
uniprot id: A0A6J3E6F7
names: Similarity
messages: Belongs to the adaptor complexes large subunit family.

219594:REL
gene id: 219594:REL
uniprot id: A0A6J3CQH4
uniprot id: A0A6J3CRJ3
names: Subcellular Location Annotation
messages: Nucleus

219594:LOC116499657
gene id: 219594:LOC116499657
uniprot id: A0A6J3EEK9
names: Similarity
names: Subunit
messages: Belongs to the avian keratin family.
messages: The avian keratins (F-ker, S-ker, C-ker and B-ker) are a complex mixture of very similar polypeptides.

219594:HIPK4
gene id: 219594:HIPK4
uniprot id: A0A6J3CSN3
names: Similarity
messages: Belongs to the protein kinase superfamily.

219594:CBFB
gene id: 219594:CBFB
uniprot id: A0A6J3DJX9
uniprot id: A0A6J3DP64
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CBF-beta family.
messages: Nucleus

219594:XYLB
gene id: 219594:XYLB
uniprot id: A0A6J3CJW9
uniprot id: A0A6J3CLC6
uniprot id: A0A6J3CPL2
uniprot id: A0A6J3CQV4
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Phosphorylates D-xylulose to produce D-xylulose 5-phosphate, a molecule that may play an important role in the regulation of glucose metabolism and lipogenesis.

219594:EPN2
gene id: 219594:EPN2
uniprot id: A0A6J3DPI3
uniprot id: A0A6J3DTU0
names: Similarity
messages: Belongs to the epsin family.

219594:SIX1
gene id: 219594:SIX1
uniprot id: A0A6J3CY80
names: Subcellular Location Annotation
messages: Nucleus

219594:CEP44
gene id: 219594:CEP44
uniprot id: A0A6J3CVU0
names: Subcellular Location Annotation
messages: Midbody
messages: centriole
messages: spindle pole

219594:RUVBL1
gene id: 219594:RUVBL1
uniprot id: A0A6J3DKI9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RuvB family.
messages: Dynein axonemal particle
messages: Nucleus
messages: Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding.

219594:ARHGDIB
gene id: 219594:ARHGDIB
uniprot id: A0A6J3EG41
names: Similarity
messages: Belongs to the Rho GDI family.

219594:ARID3A
gene id: 219594:ARID3A
uniprot id: A0A6J3E7L8
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Homodimer.
messages: Nucleus
messages: Transcription factor.

219594:TK1
gene id: 219594:TK1
uniprot id: A0A6J3E2I2
names: Similarity
messages: Belongs to the thymidine kinase family.

219594:CSTF2
gene id: 219594:CSTF2
uniprot id: A0A6J3DLY3
uniprot id: A0A6J3DS54
names: Subcellular Location Annotation
messages: Nucleus

219594:MRPL13
gene id: 219594:MRPL13
uniprot id: A0A6J3CGB2
names: Similarity
messages: Belongs to the universal ribosomal protein uL13 family.

219594:HAPLN3
gene id: 219594:HAPLN3
uniprot id: A0A6J3DHZ9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:C12H16orf87
gene id: 219594:C12H16orf87
uniprot id: A0A6J3DQ67
names: Similarity
messages: Belongs to the UPF0547 family.

219594:EYA2
gene id: 219594:EYA2
uniprot id: A0A6J3DX98
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HAD-like hydrolase superfamily. EYA family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Nucleus

219594:ADD3
gene id: 219594:ADD3
uniprot id: A0A6J3D8Q9
uniprot id: A0A6J3D8R5
names: Similarity
messages: Belongs to the aldolase class II family. Adducin subfamily.

219594:IHH
gene id: 219594:IHH
uniprot id: A0A6J3D7Z3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the hedgehog family.
messages: Cell membrane
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Membrane
messages: Multimer.
messages: The C-terminal part of the hedgehog protein precursor displays an autoproteolysis activity that results in the cleavage of the full-length protein into two parts (N-product and C-product). In addition, the C-terminal part displays a cholesterol transferase activity that results by the covalent attachment of a cholesterol moiety to the C-terminal of the newly generated N-product.
messages: The dually lipidated hedgehog protein N-product is a morphogen which is essential for a variety of patterning events during development.

219594:PFDN4
gene id: 219594:PFDN4
uniprot id: A0A6J3DU00
names: Function
names: Similarity
names: Subunit
messages: Belongs to the prefoldin subunit beta family.
messages: Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins.
messages: Heterohexamer of two PFD-alpha type and four PFD-beta type subunits.

219594:RGS9
gene id: 219594:RGS9
uniprot id: A0A6J3DYR4
names: Subcellular Location Annotation
messages: Membrane

219594:PRIM2
gene id: 219594:PRIM2
uniprot id: A0A6J3CRG7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the eukaryotic-type primase large subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Regulatory subunit of the DNA primase complex and component of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which play an essential role in the initiation of DNA synthesis. The primase subunit of the polymerase alpha complex initiates DNA synthesis by oligomerising short RNA primers on both leading and lagging strands.

219594:DOCK1
gene id: 219594:DOCK1
uniprot id: A0A6J3D5S0
uniprot id: A0A6J3DBM6
names: Similarity
messages: Belongs to the DOCK family.

219594:VPS35L
gene id: 219594:VPS35L
uniprot id: A0A6J3DR85
uniprot id: A0A6J3DU60
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VPS35L family.
messages: Endosome

219594:TRAPPC13
gene id: 219594:TRAPPC13
uniprot id: A0A6J3EE91
uniprot id: A0A6J3EFP7
uniprot id: A0A6J3EJ93
uniprot id: A0A6J3EL02
names: Similarity
names: Subunit
messages: Belongs to the TRAPPC13 family.
messages: Part of the multisubunit TRAPP (transport protein particle) complex.

219594:LOC116496010
gene id: 219594:LOC116496010
uniprot id: A0A6J3DVF9
names: Similarity
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.

219594:REM1
gene id: 219594:REM1
uniprot id: A0A6J3DYG7
names: Similarity
messages: Belongs to the small GTPase superfamily. RGK family.

219594:NOL8
gene id: 219594:NOL8
uniprot id: A0A6J3DJB2
names: Subcellular Location Annotation
messages: nucleolus

219594:LOC116488900
gene id: 219594:LOC116488900
uniprot id: A0A6J3CUL5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Toll-like receptor family.
messages: Cooperates with LY96 to mediate the innate immune response to bacterial lipoproteins and other microbial cell wall components. Cooperates with TLR1 or TLR6 to mediate the innate immune response to bacterial lipoproteins or lipopeptides. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response.
messages: Membrane

219594:LOC116486751
gene id: 219594:LOC116486751
uniprot id: A0A6J3CM13
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily.

219594:NUP93
gene id: 219594:NUP93
uniprot id: A0A6J3DLL4
uniprot id: A0A6J3DLL8
uniprot id: A0A6J3DN95
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleoporin interacting component (NIC) family.
messages: Nucleus membrane
messages: Plays a role in the nuclear pore complex (NPC) assembly and/or maintenance.
messages: nuclear pore complex

219594:EIF4E3
gene id: 219594:EIF4E3
uniprot id: A0A6J3DIL1
uniprot id: A0A6J3DLZ4
names: Similarity
messages: Belongs to the eukaryotic initiation factor 4E family.

219594:LOC116499495
gene id: 219594:LOC116499495
uniprot id: A0A6J3E8V9
uniprot id: A0A6J3EE05
names: Subcellular Location Annotation
messages: Nucleus

219594:CZIB
gene id: 219594:CZIB
uniprot id: A0A6J3D903
uniprot id: A0A6J3DBQ6
uniprot id: A0A6J3DEQ2
names: Similarity
messages: Belongs to the UPF0587 family.

219594:MCL1
gene id: 219594:MCL1
uniprot id: A0A6J3EF18
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Bcl-2 family.
messages: Cytoplasm
messages: nucleoplasm

219594:PRKCZ
gene id: 219594:PRKCZ
uniprot id: A0A6J3E2V3
uniprot id: A0A6J3E7Q3
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.

219594:FAHD1
gene id: 219594:FAHD1
uniprot id: A0A6J3DVL2
names: Similarity
messages: Belongs to the FAH family.

219594:NDUFAF1
gene id: 219594:NDUFAF1
uniprot id: A0A6J3CYY1
names: Function
names: Similarity
messages: As part of the MCIA complex, involved in the assembly of the mitochondrial complex I.
messages: Belongs to the CIA30 family.

219594:LPL
gene id: 219594:LPL
uniprot id: A0A6J3EFG5
uniprot id: A0A6J3EKM5
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AB hydrolase superfamily. Lipase family.
messages: Cell membrane
messages: Homodimer. Interacts with APOC2; the interaction activates LPL activity in the presence of lipids.
messages: Key enzyme in triglyceride metabolism. Catalyzes the hydrolysis of triglycerides from circulating chylomicrons and very low density lipoproteins (VLDL), and thereby plays an important role in lipid clearance from the blood stream, lipid utilization and storage. Mediates margination of triglyceride-rich lipoprotein particles in capillaries. Recruited to its site of action on the luminal surface of vascular endothelium by binding to GPIHBP1 and cell surface heparan sulfate proteoglycans.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted
messages: Tyrosine nitration after lipopolysaccharide (LPS) challenge down-regulates the lipase activity.
messages: extracellular matrix

219594:HMX1
gene id: 219594:HMX1
uniprot id: A0A6J3D181
names: Subcellular Location Annotation
messages: Nucleus

219594:LAMA1
gene id: 219594:LAMA1
uniprot id: A0A6J3CEK1
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: basement membrane

219594:LOC116498289
gene id: 219594:LOC116498289
uniprot id: A0A6J3E957
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

219594:RBP4
gene id: 219594:RBP4
uniprot id: A0A6J3DBQ1
names: Similarity
messages: Belongs to the calycin superfamily. Lipocalin family.

219594:NONO
gene id: 219594:NONO
uniprot id: A0A6J3DMU5
uniprot id: A0A6J3DPM8
names: Subcellular Location Annotation
messages: Nucleus speckle

219594:NT5C3B
gene id: 219594:NT5C3B
uniprot id: A0A6J3EAA6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrimidine 5'-nucleotidase family.
messages: Cytoplasm

219594:NAGPA
gene id: 219594:NAGPA
uniprot id: A0A6J3DWH8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:LOC116487472
gene id: 219594:LOC116487472
uniprot id: A0A6J3CMU5
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

219594:CPB1
gene id: 219594:CPB1
uniprot id: A0A6J3DJ95
names: Similarity
messages: Belongs to the peptidase M14 family.

219594:APOD
gene id: 219594:APOD
uniprot id: A0A6J3DH10
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calycin superfamily. Lipocalin family.
messages: Secreted

219594:LOC116487912
gene id: 219594:LOC116487912
uniprot id: A0A6J3CPQ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S33 family.
messages: Microsome membrane

219594:LOC116490743
gene id: 219594:LOC116490743
uniprot id: A0A6J3D739
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium channel (TC 1.A.1.10) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient.
messages: Membrane

219594:LOC116498878
gene id: 219594:LOC116498878
uniprot id: A0A6J3ED29
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR1 subfamily.
messages: Nucleus

219594:MON2
gene id: 219594:MON2
uniprot id: A0A6J3DDV9
uniprot id: A0A6J3DGM2
uniprot id: A0A6J3DGM8
uniprot id: A0A6J3DHV4
uniprot id: A0A6J3DJI0
uniprot id: A0A6J3DK06
names: Similarity
messages: Belongs to the MON2 family.

219594:SLC27A3
gene id: 219594:SLC27A3
uniprot id: A0A6J3EDP1
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

219594:EBAG9
gene id: 219594:EBAG9
uniprot id: A0A6J3CK41
names: Function
names: Subcellular Location Annotation
messages: Golgi apparatus membrane
messages: May participate in suppression of cell proliferation and induces apoptotic cell death through activation of interleukin-1-beta converting enzyme (ICE)-like proteases.

219594:MDH1
gene id: 219594:MDH1
uniprot id: A0A6J3CRV7
names: Similarity
names: Subunit
messages: Belongs to the LDH/MDH superfamily. MDH type 2 family.
messages: Homodimer.

219594:ASIC1
gene id: 219594:ASIC1
uniprot id: A0A6J3EAL0
names: Subcellular Location Annotation
messages: Membrane

219594:AIDA
gene id: 219594:AIDA
uniprot id: A0A6J3CLE9
uniprot id: A0A6J3CRB3
uniprot id: A0A6J3CSC1
names: Similarity
messages: Belongs to the AIDA family.

219594:STEAP3
gene id: 219594:STEAP3
uniprot id: A0A6J3D445
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STEAP family.
messages: Endosome membrane
messages: Membrane

219594:PCSK9
gene id: 219594:PCSK9
uniprot id: A0A6J3D9K0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S8 family.
messages: Cell surface
messages: Cytoplasm
messages: Endoplasmic reticulum
messages: Endosome
messages: Golgi apparatus
messages: Lysosome

219594:MNAT1
gene id: 219594:MNAT1
uniprot id: A0A6J3CZE9
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Associates with CDK7 and cyclin H.
messages: Nucleus
messages: Stabilizes the cyclin H-CDK7 complex to form a functional CDK-activating kinase (CAK) enzymatic complex.

219594:GPR107
gene id: 219594:GPR107
uniprot id: A0A6J3E375
names: Subcellular Location Annotation
messages: Membrane

219594:OCA2
gene id: 219594:OCA2
uniprot id: A0A6J3EEV3
names: Subcellular Location Annotation
messages: Membrane

219594:DOK6
gene id: 219594:DOK6
uniprot id: A0A6J3CG37
names: Similarity
messages: Belongs to the DOK family. Type B subfamily.

219594:PNRC2
gene id: 219594:PNRC2
uniprot id: A0A6J3E3I2
names: Subcellular Location Annotation
messages: Nucleus

219594:GNB5
gene id: 219594:GNB5
uniprot id: A0A6J3DLM1
names: Similarity
messages: Belongs to the WD repeat G protein beta family.

219594:FAM183A
gene id: 219594:FAM183A
uniprot id: A0A6J3DEM4
names: Similarity
messages: Belongs to the CFAP144 family.

219594:MRPL58
gene id: 219594:MRPL58
uniprot id: A0A6J3DXU2
names: Subcellular Location Annotation
messages: Mitochondrion

219594:IL1RAPL1
gene id: 219594:IL1RAPL1
uniprot id: A0A6J3CLZ0
uniprot id: A0A6J3CRV4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the interleukin-1 receptor family.
messages: axon
messages: dendrite

219594:PDE5A
gene id: 219594:PDE5A
uniprot id: A0A6J3CVK0
uniprot id: A0A6J3CY72
uniprot id: A0A6J3D0G7
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

219594:LOC116489104
gene id: 219594:LOC116489104
uniprot id: A0A6J3CY68
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the intercrine alpha (chemokine CxC) family.
messages: Secreted

219594:CHST4
gene id: 219594:CHST4
uniprot id: A0A6J3DQW5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 1 family. Gal/GlcNAc/GalNAc subfamily.
messages: Membrane

219594:FGFBP2
gene id: 219594:FGFBP2
uniprot id: A0A6J3CXC8
names: Similarity
messages: Belongs to the fibroblast growth factor-binding protein family.

219594:LOC116487933
gene id: 219594:LOC116487933
uniprot id: A0A6J3CUS2
names: Similarity
messages: Belongs to the major facilitator (TC 2.A.1) superfamily. Organic cation transporter (TC 2.A.1.19) family.

219594:IL26
gene id: 219594:IL26
uniprot id: A0A6J3E682
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IL-10 family.
messages: Immune regulatory cytokine.
messages: Secreted

219594:SS18
gene id: 219594:SS18
uniprot id: A0A6J3CEY1
uniprot id: A0A6J3CGK5
uniprot id: A0A6J3CJG0
names: Similarity
messages: Belongs to the SS18 family.

219594:LOC116500281
gene id: 219594:LOC116500281
uniprot id: A0A6J3EIB6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

219594:RRH
gene id: 219594:RRH
uniprot id: A0A6J3D0J8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

219594:QKI
gene id: 219594:QKI
uniprot id: A0A6J3CMA3
uniprot id: A0A6J3CMA6
uniprot id: A0A6J3CMB0
uniprot id: A0A6J3CP35
uniprot id: A0A6J3CP39
uniprot id: A0A6J3CP44
uniprot id: A0A6J3CPY2
uniprot id: A0A6J3CS87
uniprot id: A0A6J3CS91
uniprot id: A0A6J3CS97
uniprot id: A0A6J3CTC3
uniprot id: A0A6J3CTC6
uniprot id: A0A6J3CTD1
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

219594:VANGL1
gene id: 219594:VANGL1
uniprot id: A0A6J3EPM3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Vang family.
messages: Cell membrane
messages: Membrane

219594:CARMIL2
gene id: 219594:CARMIL2
uniprot id: A0A6J3DQC3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CARMIL family.
messages: Cytoplasm

219594:SMARCD3
gene id: 219594:SMARCD3
uniprot id: A0A6J3CJP6
uniprot id: A0A6J3CJQ6
uniprot id: A0A6J3CL48
uniprot id: A0A6J3CL62
uniprot id: A0A6J3CMA8
uniprot id: A0A6J3CMB2
uniprot id: A0A6J3CPB1
uniprot id: A0A6J3CQM9
names: Similarity
messages: Belongs to the SMARCD family.

219594:CCNJ
gene id: 219594:CCNJ
uniprot id: A0A6J3DDY2
names: Similarity
messages: Belongs to the cyclin family.

219594:DIS3L2
gene id: 219594:DIS3L2
uniprot id: A0A6J3DDB8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-5'-exoribonuclease that specifically recognizes RNAs polyuridylated at their 3' end and mediates their degradation. Component of an exosome-independent RNA degradation pathway that mediates degradation of both mRNAs and miRNAs that have been polyuridylated by a terminal uridylyltransferase. Essential for correct mitosis, and negatively regulates cell proliferation.
messages: Belongs to the RNR ribonuclease family. DIS3L2 subfamily.
messages: Cytoplasm
messages: P-body
messages: Specifically recognizes and binds polyuridylated RNAs via 3 RNA-binding regions (named U-zone 1, U-zone 2 and U-zone 3) that form an open funnel on one face of the catalytic domain, allowing RNA to navigate a path to the active site.

219594:CA5A
gene id: 219594:CA5A
uniprot id: A0A6J3DJ26
uniprot id: A0A6J3DN87
uniprot id: A0A6J3DPH5
names: Function
names: Similarity
messages: Belongs to the alpha-carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

219594:GPN1
gene id: 219594:GPN1
uniprot id: A0A6J3CLW3
uniprot id: A0A6J3CNL6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GPN-loop GTPase family.
messages: Binds to RNA polymerase II.
messages: Cytoplasm
messages: Nucleus
messages: Small GTPase required for proper nuclear import of RNA polymerase II (RNAPII). May act at an RNAP assembly step prior to nuclear import.

219594:DLGAP2
gene id: 219594:DLGAP2
uniprot id: A0A6J3CPB5
uniprot id: A0A6J3CRA7
uniprot id: A0A6J3CRB0
uniprot id: A0A6J3CRY8
uniprot id: A0A6J3CUA3
uniprot id: A0A6J3CVF1
names: Similarity
messages: Belongs to the SAPAP family.

219594:LOC116490045
gene id: 219594:LOC116490045
uniprot id: A0A6J3D0G2
uniprot id: A0A6J3D5F0
uniprot id: A0A6J3D6C6
names: Similarity
messages: Belongs to the actin family.

219594:LOC116491356
gene id: 219594:LOC116491356
uniprot id: A0A6J3DA58
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AB hydrolase superfamily. Lipase family.
messages: Secreted

219594:TNRC6B
gene id: 219594:TNRC6B
uniprot id: A0A6J3EPA5
names: Similarity
messages: Belongs to the GW182 family.

219594:TRAF4
gene id: 219594:TRAF4
uniprot id: A0A6J3E196
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TNF receptor-associated factor family.
messages: Cytoplasm

219594:AFF4
gene id: 219594:AFF4
uniprot id: A0A6J3DM90
names: Similarity
messages: Belongs to the AF4 family.

219594:NDUFA6
gene id: 219594:NDUFA6
uniprot id: A0A6J3ENN6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed to be not involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I LYR family.
messages: Mammalian complex I is composed of 45 different subunits.
messages: Mitochondrion inner membrane

219594:DNAH9
gene id: 219594:DNAH9
uniprot id: A0A6J3E146
names: Similarity
messages: Belongs to the dynein heavy chain family.

219594:SPTBN1
gene id: 219594:SPTBN1
uniprot id: A0A6J3CWS2
uniprot id: A0A6J3CXV9
names: Similarity
messages: Belongs to the spectrin family.

219594:ETV1
gene id: 219594:ETV1
uniprot id: A0A6J3CIS0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

219594:HDAC7
gene id: 219594:HDAC7
uniprot id: A0A6J3EFV7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone deacetylase family. HD type 2 subfamily.
messages: Nucleus
messages: Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.

219594:BORCS8
gene id: 219594:BORCS8
uniprot id: A0A6J3E7C9
uniprot id: A0A6J3ECF4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BORCS8 family.
messages: Lysosome membrane
messages: Membrane

219594:ACAP2
gene id: 219594:ACAP2
uniprot id: A0A6J3DBB6
uniprot id: A0A6J3DDY0
uniprot id: A0A6J3DF24
uniprot id: A0A6J3DGV6
names: Activity Regulation
names: Domain
names: Function
names: Subcellular Location Annotation
messages: Endosome membrane
messages: GAP activity stimulated by phosphatidylinositol 4,5-bisphosphate (PIP2) and phosphatidic acid.
messages: GTPase-activating protein for the ADP ribosylation factor family.
messages: PH domain binds phospholipids including phosphatidic acid, phosphatidylinositol 3-phosphate, phosphatidylinositol 3,5-bisphosphate (PIP2) and phosphatidylinositol 3,4,5-trisphosphate (PIP3). May mediate protein binding to PIP2 or PIP3 containing membranes.
messages: The BAR domain mediates homodimerization, it can neither bind membrane nor impart curvature, but instead requires the neighboring PH domain to achieve these functions.

219594:HSDL1
gene id: 219594:HSDL1
uniprot id: A0A6J3DJV8
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

219594:PUS3
gene id: 219594:PUS3
uniprot id: A0A6J3E774
names: Similarity
messages: Belongs to the tRNA pseudouridine synthase TruA family.

219594:TNC
gene id: 219594:TNC
uniprot id: A0A6J3DXH6
uniprot id: A0A6J3E2H6
uniprot id: A0A6J3E3K5
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tenascin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

219594:EPHA5
gene id: 219594:EPHA5
uniprot id: A0A6J3CT40
uniprot id: A0A6J3CVG5
uniprot id: A0A6J3CVW1
uniprot id: A0A6J3CVW6
uniprot id: A0A6J3CY78
uniprot id: A0A6J3CZA3
names: Subcellular Location Annotation
messages: Membrane

219594:SCNN1D
gene id: 219594:SCNN1D
uniprot id: A0A6J3E4Y1
names: Subcellular Location Annotation
messages: Membrane

219594:LOC116487510
gene id: 219594:LOC116487510
uniprot id: A0A6J3CU05
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor T2R family.
messages: Membrane

219594:SLC30A6
gene id: 219594:SLC30A6
uniprot id: A0A6J3CVC4
uniprot id: A0A6J3CWH8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily.
messages: Membrane

219594:FBLN5
gene id: 219594:FBLN5
uniprot id: A0A6J3D0J6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:CACNA1C
gene id: 219594:CACNA1C
uniprot id: A0A6J3D2N7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. CACNA1C subfamily.
messages: Cell membrane
messages: Membrane
messages: Perikaryon
messages: Postsynaptic density membrane
messages: T-tubule
messages: Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death.
messages: dendrite
messages: sarcolemma

219594:UTS2B
gene id: 219594:UTS2B
uniprot id: A0A6J3DDX6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the urotensin-2 family.
messages: Secreted

219594:POU2F1
gene id: 219594:POU2F1
uniprot id: A0A6J3EJU5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the POU transcription factor family. Class-2 subfamily.
messages: Nucleus

219594:LOC116488953
gene id: 219594:LOC116488953
uniprot id: A0A6J3CXG8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IL-12B family.
messages: Belongs to the type I cytokine receptor family. Type 3 subfamily.
messages: Heterodimer with IL12A; disulfide-linked. The heterodimer is known as interleukin IL-12.
messages: Secreted

219594:SST
gene id: 219594:SST
uniprot id: A0A6J3DFR0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the somatostatin family.
messages: Secreted

219594:HOXC5
gene id: 219594:HOXC5
uniprot id: A0A6J3EBY6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Antp homeobox family.
messages: Nucleus

219594:AK4
gene id: 219594:AK4
uniprot id: A0A6J3DB31
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family. AK3 subfamily.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon GTP/ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent GTP/ATP hydrolysis.
messages: Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Efficiently phosphorylates AMP and dAMP using ATP as phosphate donor, but phosphorylates only AMP when using GTP as phosphate donor. Also displays broad nucleoside diphosphate kinase activity.
messages: Mitochondrion matrix
messages: Monomer.

219594:LOC116486627
gene id: 219594:LOC116486627
uniprot id: A0A6J3CLI7
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily.

219594:SELENOT
gene id: 219594:SELENOT
uniprot id: A0A6J3DFQ5
names: Similarity
messages: Belongs to the SelWTH family. Selenoprotein T subfamily.

219594:ELOVL5
gene id: 219594:ELOVL5
uniprot id: A0A6J3CR81
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELO family. ELOVL5 subfamily.
messages: Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that acts specifically toward polyunsaturated acyl-CoA with the higher activity toward C18:3(n-6) acyl-CoA. May participate to the production of monounsaturated and of polyunsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: dendrite

219594:MMP23B
gene id: 219594:MMP23B
uniprot id: A0A6J3E0N9
uniprot id: A0A6J3E4W8
uniprot id: A0A6J3E5P0
names: Caution
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M10A family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Can bind about 5 Ca(2+) ions per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:LOC116499861
gene id: 219594:LOC116499861
uniprot id: A0A6J3EGZ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM198 family.
messages: Membrane

219594:NUBP2
gene id: 219594:NUBP2
uniprot id: A0A6J3DSM4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family. NUBP2/CFD1 subfamily.
messages: Binds 4 [4Fe-4S] clusters per heterotetramer. Contains two stable clusters in the N-termini of NUBP1 and two labile, bridging clusters between subunits of the NUBP1-NUBP2 heterotetramer.
messages: Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery. Required for maturation of extramitochondrial Fe-S proteins. The NUBP1-NUBP2 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins.
messages: Cytoplasm
messages: Heterotetramer of 2 NUBP1 and 2 NUBP2 chains.

219594:PKIG
gene id: 219594:PKIG
uniprot id: A0A6J3DY81
names: Function
names: Similarity
messages: Belongs to the PKI family.
messages: Extremely potent competitive inhibitor of cAMP-dependent protein kinase activity, this protein interacts with the catalytic subunit of the enzyme after the cAMP-induced dissociation of its regulatory chains.

219594:LOC116499338
gene id: 219594:LOC116499338
uniprot id: A0A6J3EF28
names: Similarity
messages: Belongs to the nucleoplasmin family.

219594:MTHFD1
gene id: 219594:MTHFD1
uniprot id: A0A6J3D4H6
names: Similarity
names: Subunit
messages: Homodimer.
messages: In the C-terminal section; belongs to the formate--tetrahydrofolate ligase family.
messages: In the N-terminal section; belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.

219594:LOC116495085
gene id: 219594:LOC116495085
uniprot id: A0A6J3DV18
names: Subcellular Location Annotation
names: Subunit
messages: Cell membrane
messages: Interacts with NCDN.
messages: Membrane

219594:LOC116494475
gene id: 219594:LOC116494475
uniprot id: A0A6J3DLC0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

219594:LOC116500648
gene id: 219594:LOC116500648
uniprot id: A0A6J3EI31
names: Similarity
messages: Belongs to the osteocalcin/matrix Gla protein family.

219594:LOC116497777
gene id: 219594:LOC116497777
uniprot id: A0A6J3E664
names: Subcellular Location Annotation
messages: Secreted

219594:CHST14
gene id: 219594:CHST14
uniprot id: A0A6J3CXM2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 2 family.
messages: Golgi apparatus membrane
messages: Membrane

219594:RBP1
gene id: 219594:RBP1
uniprot id: A0A6J3DIS6
names: Similarity
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.

219594:NFKB1
gene id: 219594:NFKB1
uniprot id: A0A6J3CU93
uniprot id: A0A6J3CUR9
uniprot id: A0A6J3CX26
uniprot id: A0A6J3CY63
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

219594:MMUT
gene id: 219594:MMUT
uniprot id: A0A6J3CUN9
names: Function
names: Similarity
messages: Belongs to the methylmalonyl-CoA mutase family.
messages: Catalyzes the reversible isomerization of methylmalonyl-CoA (MMCoA) (generated from branched-chain amino acid metabolism and degradation of dietary odd chain fatty acids and cholesterol) to succinyl-CoA (3-carboxypropionyl-CoA), a key intermediate of the tricarboxylic acid cycle.

219594:RNF146
gene id: 219594:RNF146
uniprot id: A0A6J3CP68
names: Domain
names: Function
names: PTM
names: Subcellular Location Annotation
messages: E3 ubiquitin-protein ligase that specifically binds poly-ADP-ribosylated proteins and mediates their ubiquitination and subsequent degradation.
messages: The WWE domain mediates non-covalent poly(ADP-ribose)-binding.
messages: Ubiquitinated; autoubiquitinated.
messages: cytosol

219594:TMEM126A
gene id: 219594:TMEM126A
uniprot id: A0A6J3DLD5
names: Subcellular Location Annotation
messages: Membrane

219594:POLR3A
gene id: 219594:POLR3A
uniprot id: A0A6J3DCX8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA polymerase beta' chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Nucleus

219594:ABCA5
gene id: 219594:ABCA5
uniprot id: A0A6J3DWJ3
names: Subcellular Location Annotation
messages: Membrane

219594:PAN3
gene id: 219594:PAN3
uniprot id: A0A6J3CEZ5
uniprot id: A0A6J3CGM9
uniprot id: A0A6J3CGN9
uniprot id: A0A6J3CL70
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the protein kinase superfamily. PAN3 family.
messages: Contains a pseudokinase domain. The protein kinase domain is predicted to be catalytically inactive because some of the residues important for catalytic activity are substituted and it lacks the equivalent of the binding site for a peptide substrate. However, it has retained an ATP-binding site and ATP-binding is required for mRNA degradation, stimulating the activity of the PAN2 nuclease in vitro. The nucleotide-binding site is juxtaposed to the RNase active site of PAN2 in the complex and may actually bind nucleosides of a poly(A) RNA rather than ATP, feeding the poly(A)-tail to the active site of the deadenylase and thus increasing the efficiency with which this distributive enzyme degrades oligo(A) RNAs.
messages: Cytoplasm
messages: Homodimer. Forms a heterotrimer with a catalytic subunit PAN2 to form the poly(A)-nuclease (PAN) deadenylation complex. Interacts (via PAM-2 motif) with poly(A)-binding protein PABPC1 (via PABC domain), conferring substrate specificity of the enzyme complex. Interacts with the GW182 family proteins TNRC6A, TNRC6B and TNRC6C.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: P-body
messages: Regulatory subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in general and miRNA-mediated mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein (PABP). PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent mRNA decaping and subsequent 5'-3' exonucleolytic degradation by XRN1. PAN3 acts as a positive regulator for PAN activity, recruiting the catalytic subunit PAN2 to mRNA via its interaction with RNA and PABP, and to miRNA targets via its interaction with GW182 family proteins.
messages: The N-terminal zinc finger binds to poly(A) RNA.
messages: The pseudokinase domain, the coiled-coil (CC), and C-terminal knob domain (CK) form a structural unit (PKC) that forms an extensive high-affinity interaction surface for PAN2.

219594:HS2ST1
gene id: 219594:HS2ST1
uniprot id: A0A6J3DGD5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 3 family.
messages: Golgi apparatus membrane
messages: Membrane

219594:IFT57
gene id: 219594:IFT57
uniprot id: A0A6J3ERS7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IFT57 family.
messages: cilium basal body

219594:PDCL
gene id: 219594:PDCL
uniprot id: A0A6J3E3M8
names: Similarity
messages: Belongs to the phosducin family.

219594:LOC116485598
gene id: 219594:LOC116485598
uniprot id: A0A6J3CEX8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:PIK3CD
gene id: 219594:PIK3CD
uniprot id: A0A6J3E5J1
names: Similarity
messages: Belongs to the PI3/PI4-kinase family. Type III PI4K subfamily.

219594:SEPTIN11
gene id: 219594:SEPTIN11
uniprot id: A0A6J3CTI9
uniprot id: A0A6J3CVU8
uniprot id: A0A6J3CW93
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.

219594:CAMKMT
gene id: 219594:CAMKMT
uniprot id: A0A6J3CSM7
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

219594:PPP2R5A
gene id: 219594:PPP2R5A
uniprot id: A0A6J3CKV0
names: Similarity
messages: Belongs to the phosphatase 2A regulatory subunit B56 family.

219594:COPB2
gene id: 219594:COPB2
uniprot id: A0A6J3DHN0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the WD repeat COPB2 family.
messages: COPI-coated vesicle membrane
messages: Golgi apparatus membrane
messages: Membrane
messages: Oligomeric complex that consists of at least the alpha, beta, beta', gamma, delta, epsilon and zeta subunits.
messages: The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. In mammals, the coatomer can only be recruited by membranes associated to ADP-ribosylation factors (ARFs), which are small GTP-binding proteins; the complex also influences the Golgi structural integrity, as well as the processing, activity, and endocytic recycling of LDL receptors.
messages: This coatomer complex protein, essential for Golgi budding and vesicular trafficking, is a selective binding protein (RACK) for protein kinase C, epsilon type. It binds to Golgi membranes in a GTP-dependent manner.

219594:STON2
gene id: 219594:STON2
uniprot id: A0A6J3D4R2
uniprot id: A0A6J3D5P7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Stoned B family.
messages: Cytoplasm

219594:KLHL15
gene id: 219594:KLHL15
uniprot id: A0A6J3DG30
names: Subcellular Location Annotation
messages: Nucleus

219594:SUB1
gene id: 219594:SUB1
uniprot id: A0A6J3EI19
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transcriptional coactivator PC4 family.
messages: General coactivator that functions cooperatively with TAFs and mediates functional interactions between upstream activators and the general transcriptional machinery. May be involved in stabilizing the multiprotein transcription complex. Binds single-stranded DNA. Also binds, in vitro, non-specifically to double-stranded DNA (ds DNA).
messages: Nucleus

219594:NHP2
gene id: 219594:NHP2
uniprot id: A0A6J3DU11
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic ribosomal protein eL8 family.
messages: Common component of the spliceosome and rRNA processing machinery.
messages: nucleolus

219594:MRPL2
gene id: 219594:MRPL2
uniprot id: A0A6J3CTZ2
names: Similarity
messages: Belongs to the universal ribosomal protein uL2 family.

219594:MVP
gene id: 219594:MVP
uniprot id: A0A6J3EG04
names: Subcellular Location Annotation
messages: Cytoplasm

219594:UNC50
gene id: 219594:UNC50
uniprot id: A0A6J3CJA4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the unc-50 family.
messages: Membrane
messages: Nucleus inner membrane

219594:PYGB
gene id: 219594:PYGB
uniprot id: A0A6J3CU10
names: Function
names: Similarity
messages: Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis.
messages: Belongs to the glycogen phosphorylase family.

219594:NGLY1
gene id: 219594:NGLY1
uniprot id: A0A6J3CL07
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transglutaminase-like superfamily. PNGase family.
messages: Cytoplasm
messages: Specifically deglycosylates the denatured form of N-linked glycoproteins in the cytoplasm and assists their proteasome-mediated degradation. Cleaves the beta-aspartyl-glucosamine (GlcNAc) of the glycan and the amide side chain of Asn, converting Asn to Asp. Prefers proteins containing high-mannose over those bearing complex type oligosaccharides. Can recognize misfolded proteins in the endoplasmic reticulum that are exported to the cytosol to be destroyed and deglycosylate them, while it has no activity toward native proteins. Deglycosylation is a prerequisite for subsequent proteasome-mediated degradation of some, but not all, misfolded glycoproteins.

219594:CITED2
gene id: 219594:CITED2
uniprot id: A0A6J3CUG8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CITED family.
messages: Nucleus

219594:ACOX1
gene id: 219594:ACOX1
uniprot id: A0A6J3E0V1
uniprot id: A0A6J3E200
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acyl-CoA oxidase family.
messages: Peroxisome

219594:ADAMTS6
gene id: 219594:ADAMTS6
uniprot id: A0A6J3EGY1
uniprot id: A0A6J3EM68
names: Caution
names: Cofactor
names: Subcellular Location Annotation
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

219594:TTC25
gene id: 219594:TTC25
uniprot id: A0A6J3E8I3
names: Subcellular Location Annotation
messages: cilium axoneme

219594:SLCO3A1
gene id: 219594:SLCO3A1
uniprot id: A0A6J3DLX0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the organo anion transporter (TC 2.A.60) family.
messages: Cell membrane
messages: Membrane
messages: Secreted

219594:DNAAF1
gene id: 219594:DNAAF1
uniprot id: A0A6J3DJL0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNAAF1 family.
messages: Cilium-specific protein required for the stability of the ciliary architecture. Plays a role in cytoplasmic preassembly of dynein arms. Involved in regulation of microtubule-based cilia and actin-based brush border microvilli.
messages: cilium

219594:MRPL53
gene id: 219594:MRPL53
uniprot id: A0A6J3CI76
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mL53 family.
messages: Mitochondrion

219594:LOC116496070
gene id: 219594:LOC116496070
uniprot id: A0A6J3DVU8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dynein light chain family.
messages: cytoskeleton

219594:EEF1B2
gene id: 219594:EEF1B2
uniprot id: A0A6J3D4Z5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the EF-1-beta/EF-1-delta family.
messages: EF-1 is composed of 4 subunits: alpha, beta, delta, and gamma.
messages: EF-1-beta and EF-1-delta stimulate the exchange of GDP bound to EF-1-alpha to GTP.

219594:RICTOR
gene id: 219594:RICTOR
uniprot id: A0A6J3EDF7
uniprot id: A0A6J3EH55
uniprot id: A0A6J3EIR7
names: Similarity
messages: Belongs to the RICTOR family.

219594:ZAR1L
gene id: 219594:ZAR1L
uniprot id: A0A6J3E687
names: Similarity
messages: Belongs to the ZAR1 family.

219594:PHOSPHO2
gene id: 219594:PHOSPHO2
uniprot id: A0A6J3D5S3
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. PHOSPHO family.

219594:CERCAM
gene id: 219594:CERCAM
uniprot id: A0A6J3DYP2
uniprot id: A0A6J3E3S3
names: Similarity
messages: Belongs to the glycosyltransferase 25 family.

219594:UBE2H
gene id: 219594:UBE2H
uniprot id: A0A6J3DPH2
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

219594:NFKB2
gene id: 219594:NFKB2
uniprot id: A0A6J3DCJ8
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

219594:RPP14
gene id: 219594:RPP14
uniprot id: A0A6J3DK78
names: Similarity
messages: Belongs to the eukaryotic/archaeal RNase P protein component 2 family.

219594:LOC116492561
gene id: 219594:LOC116492561
uniprot id: A0A6J3DFC8
uniprot id: A0A6J3DI71
names: Similarity
messages: Belongs to the eukaryotic diacylglycerol kinase family.

219594:VDAC3
gene id: 219594:VDAC3
uniprot id: A0A6J3ED02
names: Similarity
messages: Belongs to the eukaryotic mitochondrial porin family.

219594:RPL4
gene id: 219594:RPL4
uniprot id: A0A6J3DNH2
names: Similarity
messages: Belongs to the universal ribosomal protein uL4 family.

219594:LOC116490230
gene id: 219594:LOC116490230
uniprot id: A0A6J3D780
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM151 family.
messages: Membrane

219594:TLCD4
gene id: 219594:TLCD4
uniprot id: A0A6J3DEB1
names: Subcellular Location Annotation
messages: Membrane

219594:RPGRIP1L
gene id: 219594:RPGRIP1L
uniprot id: A0A6J3DJ46
uniprot id: A0A6J3DJ51
uniprot id: A0A6J3DLM7
uniprot id: A0A6J3DNA5
uniprot id: A0A6J3DPJ3
uniprot id: A0A6J3DQ95
names: Similarity
messages: Belongs to the RPGRIP1 family.

219594:FZD7
gene id: 219594:FZD7
uniprot id: A0A6J3D608
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor Fz/Smo family.
messages: Cell membrane
messages: Endosome membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

219594:SDE2
gene id: 219594:SDE2
uniprot id: A0A6J3CT47
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SDE2 family.
messages: Cytoplasm
messages: Nucleus

219594:DAO
gene id: 219594:DAO
uniprot id: A0A6J3DT96
uniprot id: A0A6J3DY83
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DAMOX/DASOX family.
messages: Peroxisome

219594:LOC116485766
gene id: 219594:LOC116485766
uniprot id: A0A6J3CE50
uniprot id: A0A6J3CIP4
uniprot id: A0A6J3CKC7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium channel (TC 1.A.1.10) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient.
messages: Membrane

219594:GJE1
gene id: 219594:GJE1
uniprot id: A0A6J3CMW7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

219594:TUBGCP2
gene id: 219594:TUBGCP2
uniprot id: A0A6J3D9I0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TUBGCP family.
messages: Gamma-tubulin complex is necessary for microtubule nucleation at the centrosome.
messages: centrosome

219594:HOXC9
gene id: 219594:HOXC9
uniprot id: A0A6J3EF92
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Abd-B homeobox family.
messages: Nucleus
messages: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

219594:LOC116499737
gene id: 219594:LOC116499737
uniprot id: A0A6J3E9U3
names: Similarity
names: Subunit
messages: Belongs to the avian keratin family.
messages: The avian keratins (F-ker, S-ker, C-ker and B-ker) are a complex mixture of very similar polypeptides.

219594:KRR1
gene id: 219594:KRR1
uniprot id: A0A6J3EPJ2
uniprot id: A0A6J3EQX9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KRR1 family.
messages: Component of the ribosomal small subunit (SSU) processome.
messages: Required for 40S ribosome biogenesis. Involved in nucleolar processing of pre-18S ribosomal RNA and ribosome assembly.
messages: nucleolus

219594:TRMT2A
gene id: 219594:TRMT2A
uniprot id: A0A6J3DZ71
names: Caution
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:HOXD13
gene id: 219594:HOXD13
uniprot id: A0A6J3DAX1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Abd-B homeobox family.
messages: Nucleus

219594:GLS
gene id: 219594:GLS
uniprot id: A0A6J3D554
names: Similarity
messages: Belongs to the glutaminase family.

219594:STN1
gene id: 219594:STN1
uniprot id: A0A6J3DAH9
uniprot id: A0A6J3DCN5
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Component of the CST complex proposed to act as a specialized replication factor promoting DNA replication under conditions of replication stress or natural replication barriers such as the telomere duplex. The CST complex binds single-stranded DNA with high affinity in a sequence-independent manner, while isolated subunits bind DNA with low affinity by themselves. Initially the CST complex has been proposed to protect telomeres from DNA degradation. However, the CST complex has been shown to be involved in several aspects of telomere replication.
messages: Component of the CST complex.
messages: Nucleus
messages: telomere

219594:TMCO3
gene id: 219594:TMCO3
uniprot id: A0A6J3E8J1
names: Subcellular Location Annotation
messages: Membrane

219594:NAA25
gene id: 219594:NAA25
uniprot id: A0A6J3DYF9
uniprot id: A0A6J3DZJ3
names: Similarity
messages: Belongs to the MDM20/NAA25 family.

219594:CEP63
gene id: 219594:CEP63
uniprot id: A0A6J3DCT9
uniprot id: A0A6J3DGR0
uniprot id: A0A6J3DID4
uniprot id: A0A6J3DIY4
names: Similarity
messages: Belongs to the CEP63 family.

219594:ADAMTS18
gene id: 219594:ADAMTS18
uniprot id: A0A6J3DIP2
uniprot id: A0A6J3DL77
uniprot id: A0A6J3DMT2
uniprot id: A0A6J3DP58
uniprot id: A0A6J3DPU1
names: Caution
names: Cofactor
names: Subcellular Location Annotation
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

219594:AGAP3
gene id: 219594:AGAP3
uniprot id: A0A6J3CHW7
names: Similarity
messages: Belongs to the centaurin gamma-like family.

219594:TERF2IP
gene id: 219594:TERF2IP
uniprot id: A0A6J3DPM5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts both as a regulator of telomere function and as a transcription regulator. Involved in the regulation of telomere length and protection as a component of the shelterin complex (telosome). Does not bind DNA directly: recruited to telomeric double-stranded 5'-TTAGGG-3' repeats via its interaction with terf2. Independently of its function in telomeres, also acts as a transcription regulator: recruited to extratelomeric 5'-TTAGGG-3' sites via its association with terf2 or other factors, and regulates gene expression.
messages: Belongs to the RAP1 family.
messages: Homodimer.
messages: Nucleus
messages: telomere

219594:VPS29
gene id: 219594:VPS29
uniprot id: A0A6J3DU46
uniprot id: A0A6J3DYZ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acts as component of the retromer cargo-selective complex (CSC). The CSC is believed to be the core functional component of retromer or respective retromer complex variants acting to prevent missorting of selected transmembrane cargo proteins into the lysosomal degradation pathway.
messages: Belongs to the VPS29 family.
messages: Endosome membrane

219594:PSMC5
gene id: 219594:PSMC5
uniprot id: A0A6J3E9R6
names: Similarity
messages: Belongs to the AAA ATPase family.

219594:LOC116494455
gene id: 219594:LOC116494455
uniprot id: A0A6J3DRL3
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the diacylglycerol acyltransferase family.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:LOC116495464
gene id: 219594:LOC116495464
uniprot id: A0A6J3DWY5
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

219594:KCNE3
gene id: 219594:KCNE3
uniprot id: A0A6J3EKK7
names: Similarity
messages: Belongs to the potassium channel KCNE family.

219594:NCDN
gene id: 219594:NCDN
uniprot id: A0A6J3E3B1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the neurochondrin family.
messages: Postsynapse

219594:LOC116490489
gene id: 219594:LOC116490489
uniprot id: A0A6J3D8H8
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Enhances all basic T-cell responses to a foreign antigen, namely proliferation, secretion of lymphokines, up-regulation of molecules that mediate cell-cell interaction, and effective help for antibody secretion by B-cells. Essential both for efficient interaction between T and B-cells and for normal antibody responses to T-cell dependent antigens. Does not up-regulate the production of interleukin-2, but superinduces the synthesis of interleukin-10. Prevents the apoptosis of pre-activated T-cells. Plays a critical role in CD40-mediated class switching of immunoglobin isotypes.
messages: Homodimer; disulfide-linked.
messages: Membrane

219594:FOXO6
gene id: 219594:FOXO6
uniprot id: A0A6J3E8Q5
names: Subcellular Location Annotation
messages: Nucleus

219594:SFMBT1
gene id: 219594:SFMBT1
uniprot id: A0A6J3DK16
names: Subcellular Location Annotation
messages: Nucleus

219594:LOC116500788
gene id: 219594:LOC116500788
uniprot id: A0A6J3EJ76
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

219594:PENK
gene id: 219594:PENK
uniprot id: A0A6J3CKN5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the opioid neuropeptide precursor family.
messages: Secreted

219594:LIN52
gene id: 219594:LIN52
uniprot id: A0A6J3CYI0
names: Similarity
messages: Belongs to the lin-52 family.

219594:RAB33B
gene id: 219594:RAB33B
uniprot id: A0A6J3CWF1
names: Similarity
messages: Belongs to the small GTPase superfamily. Rab family.

219594:GRIA4
gene id: 219594:GRIA4
uniprot id: A0A6J3EK12
uniprot id: A0A6J3EPH0
uniprot id: A0A6J3EPP7
uniprot id: A0A6J3EPZ8
uniprot id: A0A6J3ERP0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Receptor for glutamate that functions as a ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system.

219594:SPTB
gene id: 219594:SPTB
uniprot id: A0A6J3D3D4
names: Similarity
messages: Belongs to the spectrin family.

219594:EIF1B
gene id: 219594:EIF1B
uniprot id: A0A6J3CFF0
names: Similarity
messages: Belongs to the SUI1 family.

219594:MGST1
gene id: 219594:MGST1
uniprot id: A0A6J3ENA1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MAPEG family.
messages: Membrane

219594:NUDT5
gene id: 219594:NUDT5
uniprot id: A0A6J3D9C3
names: Similarity
messages: Belongs to the Nudix hydrolase family.

219594:POLH
gene id: 219594:POLH
uniprot id: A0A6J3CUC6
names: Subcellular Location Annotation
messages: Nucleus

219594:STMN3
gene id: 219594:STMN3
uniprot id: A0A6J3DX80
names: Similarity
messages: Belongs to the stathmin family.

219594:AMOTL2
gene id: 219594:AMOTL2
uniprot id: A0A6J3DIP9
names: Similarity
messages: Belongs to the angiomotin family.

219594:SNAPIN
gene id: 219594:SNAPIN
uniprot id: A0A6J3EE35
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNAPIN family.
messages: Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes. In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. The BLOC-1 complex, in association with SNARE proteins, is also proposed to be involved in neurite extension. Plays a role in intracellular vesicle trafficking and synaptic vesicle recycling.
messages: synaptic vesicle membrane

219594:TET1
gene id: 219594:TET1
uniprot id: A0A6J3D5I1
uniprot id: A0A6J3D8Q4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TET family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Chromosome
messages: Dioxygenase that catalyzes the conversion of the modified genomic base 5-methylcytosine (5mC) into 5-hydroxymethylcytosine (5hmC) and plays a key role in epigenetic chromatin reprogramming during embryonic development.
messages: The zinc ions have a structural role.

219594:PLPP3
gene id: 219594:PLPP3
uniprot id: A0A6J3DE49
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PA-phosphatase related phosphoesterase family.
messages: Membrane

219594:MRPS36
gene id: 219594:MRPS36
uniprot id: A0A6J3ELU7
names: Subcellular Location Annotation
messages: Mitochondrion

219594:SENP5
gene id: 219594:SENP5
uniprot id: A0A6J3DE56
uniprot id: A0A6J3DFB0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C48 family.
messages: nucleolus

219594:LOC116494067
gene id: 219594:LOC116494067
uniprot id: A0A6J3DJM0
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Rieske iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: Membrane
messages: Mitochondrion inner membrane
messages: The Rieske protein is a high potential 2Fe-2S protein.

219594:C25H1orf74
gene id: 219594:C25H1orf74
uniprot id: A0A6J3E7K3
names: Similarity
messages: Belongs to the UPF0739 family.

219594:EPHA2
gene id: 219594:EPHA2
uniprot id: A0A6J3E1S8
names: Subcellular Location Annotation
messages: Membrane

219594:LOC116488125
gene id: 219594:LOC116488125
uniprot id: A0A6J3CTC1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IL-17 family.
messages: Secreted

219594:RETREG1
gene id: 219594:RETREG1
uniprot id: A0A6J3CFY1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RETREG family.
messages: Endoplasmic reticulum membrane
messages: Membrane

219594:FAM114A1
gene id: 219594:FAM114A1
uniprot id: A0A6J3D158
names: Similarity
messages: Belongs to the FAM114 family.

219594:RASGRP1
gene id: 219594:RASGRP1
uniprot id: A0A6J3D1M4
uniprot id: A0A6J3D7F6
names: Similarity
messages: Belongs to the RASGRP family.

219594:FUBP3
gene id: 219594:FUBP3
uniprot id: A0A6J3DXV4
uniprot id: A0A6J3E218
uniprot id: A0A6J3E2V8
names: Subcellular Location Annotation
messages: Cytoplasm

219594:SPOUT1
gene id: 219594:SPOUT1
uniprot id: A0A6J3DXN9
names: Similarity
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily.

219594:KCNN2
gene id: 219594:KCNN2
uniprot id: A0A6J3EDK8
uniprot id: A0A6J3EIZ3
names: Subcellular Location Annotation
messages: Membrane

219594:SBNO1
gene id: 219594:SBNO1
uniprot id: A0A6J3DZZ7
uniprot id: A0A6J3E127
names: Similarity
messages: Belongs to the SBNO family.

219594:MNX1
gene id: 219594:MNX1
uniprot id: A0A6J3CNU7
names: Subcellular Location Annotation
messages: Nucleus

219594:FOXO4
gene id: 219594:FOXO4
uniprot id: A0A6J3DQS3
names: Subcellular Location Annotation
messages: Nucleus

219594:CRB2
gene id: 219594:CRB2
uniprot id: A0A6J3DXF4
uniprot id: A0A6J3E1L0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:CCN1
gene id: 219594:CCN1
uniprot id: A0A6J3DCB1
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CCN family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

219594:CEP76
gene id: 219594:CEP76
uniprot id: A0A6J3CR29
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CEP76 family.
messages: Centrosomal protein involved in regulation of centriole duplication. Required to limit centriole duplication to once per cell cycle by preventing centriole reduplication.
messages: centriole

219594:CAVIN4
gene id: 219594:CAVIN4
uniprot id: A0A6J3CI91
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CAVIN family.
messages: caveola

219594:CREBBP
gene id: 219594:CREBBP
uniprot id: A0A6J3DP32
uniprot id: A0A6J3DRD8
uniprot id: A0A6J3DTC8
uniprot id: A0A6J3DUC5
uniprot id: A0A6J3DUC9
uniprot id: A0A6J3DV67
uniprot id: A0A6J3DV74
names: Subcellular Location Annotation
messages: Cytoplasm

219594:CBL
gene id: 219594:CBL
uniprot id: A0A6J3E460
names: Domain
names: Function
messages: E3 ubiquitin-protein ligase which accepts ubiquitin from specific E2 ubiquitin-conjugating enzymes, and transfers it to substrates, generally promoting their degradation by the proteasome.
messages: The N-terminus is composed of the phosphotyrosine binding (PTB) domain, a short linker region and the RING-type zinc finger. The PTB domain, which is also called TKB (tyrosine kinase binding) domain, is composed of three different subdomains: a four-helix bundle (4H), a calcium-binding EF hand and a divergent SH2 domain.

219594:MIEF2
gene id: 219594:MIEF2
uniprot id: A0A6J3DVG9
names: Subcellular Location Annotation
messages: Membrane
messages: Mitochondrion outer membrane

219594:PCSK7
gene id: 219594:PCSK7
uniprot id: A0A6J3E744
names: Similarity
messages: Belongs to the peptidase S8 family.

219594:PRKD1
gene id: 219594:PRKD1
uniprot id: A0A6J3D304
uniprot id: A0A6J3D427
names: Activity Regulation
names: Similarity
names: Subcellular Location Annotation
messages: Activated by DAG and phorbol esters.
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. PKD subfamily.
messages: Cytoplasm
messages: Membrane

219594:IL23A
gene id: 219594:IL23A
uniprot id: A0A6J3EA89
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IL-6 superfamily.
messages: Secreted

219594:LOC116498551
gene id: 219594:LOC116498551
uniprot id: A0A6J3EA55
names: Similarity
names: Subunit
messages: Belongs to the avian keratin family.
messages: The avian keratins (F-ker, S-ker, C-ker and B-ker) are a complex mixture of very similar polypeptides.

219594:LDHA
gene id: 219594:LDHA
uniprot id: A0A6J3D2G5
names: Similarity
messages: Belongs to the LDH/MDH superfamily. LDH family.

219594:LOC116502173
gene id: 219594:LOC116502173
uniprot id: A0A6J3EPN4
names: Similarity
messages: Belongs to the 3-beta-HSD family.

219594:ATP1A1
gene id: 219594:ATP1A1
uniprot id: A0A6J3DM74
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIC subfamily.
messages: Cell membrane

219594:LOC116499018
gene id: 219594:LOC116499018
uniprot id: A0A6J3E720
names: Similarity
messages: Belongs to the perilipin family.

219594:LOC116488993
gene id: 219594:LOC116488993
uniprot id: A0A6J3CXM4
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

219594:RPIA
gene id: 219594:RPIA
uniprot id: A0A6J3CWK5
names: Similarity
messages: Belongs to the ribose 5-phosphate isomerase family.

219594:SLIT1
gene id: 219594:SLIT1
uniprot id: A0A6J3D5T9
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

219594:SKOR2
gene id: 219594:SKOR2
uniprot id: A0A6J3EEY0
names: Similarity
messages: Belongs to the SKI family.

219594:CAST
gene id: 219594:CAST
uniprot id: A0A6J3EDJ5
uniprot id: A0A6J3EH02
names: Function
names: Similarity
messages: Belongs to the protease inhibitor I27 (calpastatin) family.
messages: Specific inhibition of calpain (calcium-dependent cysteine protease). Plays a key role in postmortem tenderization of meat and have been proposed to be involved in muscle protein degradation in living tissue.

219594:LOC116494673
gene id: 219594:LOC116494673
uniprot id: A0A6J3DM49
uniprot id: A0A6J3DPG3
uniprot id: A0A6J3DRG7
uniprot id: A0A6J3DRH2
uniprot id: A0A6J3DSA8
uniprot id: A0A6J3DTE4
names: Subcellular Location Annotation
messages: Cytoplasm

219594:LOC116488011
gene id: 219594:LOC116488011
uniprot id: A0A6J3CW70
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily.
messages: Cell membrane
messages: Membrane
messages: Receptor for lutropin-choriogonadotropic hormone. The activity of this receptor is mediated by G proteins which activate adenylate cyclase.

219594:TDP2
gene id: 219594:TDP2
uniprot id: A0A6J3CJ34
names: Subcellular Location Annotation
messages: PML body

219594:AP1S2
gene id: 219594:AP1S2
uniprot id: A0A6J3CSL3
uniprot id: A0A6J3CSM8
uniprot id: A0A6J3CUZ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adaptor complexes small subunit family.
messages: Cytoplasmic vesicle membrane
messages: Golgi apparatus
messages: clathrin-coated pit

219594:RSRP1
gene id: 219594:RSRP1
uniprot id: A0A6J3E9D5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RSRP family.
messages: Nucleus
messages: Probably acts as a spliceosomal factor that contributes to spliceosome assembly and regulates the isoform switching of proteins such as PARP6.

219594:LOC116499113
gene id: 219594:LOC116499113
uniprot id: A0A6J3E7F9
names: Similarity
messages: Belongs to the peptidase M14 family.

219594:SLC25A27
gene id: 219594:SLC25A27
uniprot id: A0A6J3CN01
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

219594:PIGX
gene id: 219594:PIGX
uniprot id: A0A6J3DIS2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PIGX family.
messages: Endoplasmic reticulum membrane
messages: Essential component of glycosylphosphatidylinositol-mannosyltransferase 1 which transfers the first of the 4 mannoses in the GPI-anchor precursors during GPI-anchor biosynthesis.

219594:GRIA3
gene id: 219594:GRIA3
uniprot id: A0A6J3DKA2
uniprot id: A0A6J3DMR5
uniprot id: A0A6J3DMR8
uniprot id: A0A6J3DPJ0
uniprot id: A0A6J3DQQ7
uniprot id: A0A6J3DQR2
uniprot id: A0A6J3DRH3
uniprot id: A0A6J3DRH8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Receptor for glutamate that functions as a ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system.

219594:MCU
gene id: 219594:MCU
uniprot id: A0A6J3D9S2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MCU (TC 1.A.77) family.
messages: Forms a well-packed pentamer with an overall cylindrical shape. The inner core of the pentamer is formed with the second transmembrane region and the second coiled-coil region: while the transmembrane regions pack into a five-helix bundle having a largely polar pore across the membrane, the coiled-coil outside the membrane forms a pentamer with a hydrophobic core. The inner core is wrapped by the first transmembrane region through contacts between the first and the second transmembrane regions. The second transmembrane is followed by the inner juxtamembrane region (IJMH) that orients at a wide angle relative to the second transmembrane. The two core domains are held together on the periphery by the outer juxtamembrane helix (OJMH).
messages: Membrane
messages: Mitochondrial inner membrane calcium uniporter that mediates calcium uptake into mitochondria. Constitutes a pore-forming and calcium-conducting subunit. Mitochondrial calcium homeostasis plays key roles in cellular physiology and regulates cell bioenergetics, cytoplasmic calcium signals and activation of cell death pathways.
messages: Mitochondrion inner membrane

219594:SPDEF
gene id: 219594:SPDEF
uniprot id: A0A6J3E880
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

219594:ZFYVE16
gene id: 219594:ZFYVE16
uniprot id: A0A6J3EJR0
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Early endosome membrane

219594:SLC16A10
gene id: 219594:SLC16A10
uniprot id: A0A6J3CP16
names: Subcellular Location Annotation
messages: Membrane

219594:LTK
gene id: 219594:LTK
uniprot id: A0A6J3CXV6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. Insulin receptor subfamily.
messages: Cell membrane

219594:COQ10B
gene id: 219594:COQ10B
uniprot id: A0A6J3D5H1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the COQ10 family.
messages: Interacts with coenzyme Q.
messages: Required for the function of coenzyme Q in the respiratory chain. May serve as a chaperone or may be involved in the transport of Q6 from its site of synthesis to the catalytic sites of the respiratory complexes.

219594:RPS7
gene id: 219594:RPS7
uniprot id: A0A6J3CVD4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic ribosomal protein eS7 family.
messages: centrosome

219594:POMC
gene id: 219594:POMC
uniprot id: A0A6J3CR98
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the POMC family.
messages: Endogenous opiate.
messages: Secreted
messages: Stimulates the adrenal glands to release cortisol.

219594:JUP
gene id: 219594:JUP
uniprot id: A0A6J3E659
uniprot id: A0A6J3EB54
names: Similarity
messages: Belongs to the beta-catenin family.

219594:PTGR1
gene id: 219594:PTGR1
uniprot id: A0A6J3EEM6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NADP-dependent oxidoreductase L4BD family.
messages: Cytoplasm
messages: Monomer or homodimer.

219594:LOC116485366
gene id: 219594:LOC116485366
uniprot id: A0A6J3CID0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

219594:LOC116498751
gene id: 219594:LOC116498751
uniprot id: A0A6J3ECI3
names: Similarity
messages: Belongs to the GST superfamily. Mu family.

219594:LOC116491890
gene id: 219594:LOC116491890
uniprot id: A0A6J3DFG2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uricase family.
messages: Catalyzes the oxidation of uric acid to 5-hydroxyisourate, which is further processed to form (S)-allantoin.
messages: Peroxisome

219594:IMMP2L
gene id: 219594:IMMP2L
uniprot id: A0A6J3D9X9
uniprot id: A0A6J3DA03
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S26 family. IMP2 subfamily.
messages: Heterodimer of 2 subunits, IMMPL1 and IMMPL2.
messages: Membrane
messages: Mitochondrion inner membrane

219594:AGBL3
gene id: 219594:AGBL3
uniprot id: A0A6J3EJV2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M14 family.
messages: cytosol

219594:NEUROD1
gene id: 219594:NEUROD1
uniprot id: A0A6J3D853
names: Subcellular Location Annotation
messages: Nucleus

219594:B9D1
gene id: 219594:B9D1
uniprot id: A0A6J3DPR9
uniprot id: A0A6J3DV05
names: Subcellular Location Annotation
messages: cilium basal body

219594:NCAPH
gene id: 219594:NCAPH
uniprot id: A0A6J3EDV1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CND2 (condensin subunit 2) family.
messages: Chromosome
messages: Cytoplasm

219594:CDK10
gene id: 219594:CDK10
uniprot id: A0A6J3DLI5
names: Similarity
messages: Belongs to the protein kinase superfamily.

219594:SLC30A9
gene id: 219594:SLC30A9
uniprot id: A0A6J3CZ71
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily.
messages: Endoplasmic reticulum
messages: Membrane
messages: Mitochondrion membrane
messages: Nucleus

219594:CD81
gene id: 219594:CD81
uniprot id: A0A6J3CY54
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

219594:NDRG1
gene id: 219594:NDRG1
uniprot id: A0A6J3CF71
names: Similarity
messages: Belongs to the NDRG family.

219594:CASP3
gene id: 219594:CASP3
uniprot id: A0A6J3CVS4
names: Similarity
messages: Belongs to the peptidase C14A family.

219594:DKK2
gene id: 219594:DKK2
uniprot id: A0A6J3CY45
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dickkopf family.
messages: Secreted

219594:EIF3L
gene id: 219594:EIF3L
uniprot id: A0A6J3ECC5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-3 subunit L family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is composed of 13 subunits: EIF3A, EIF3B, EIF3C, EIF3D, EIF3E, EIF3F, EIF3G, EIF3H, EIF3I, EIF3J, EIF3K, EIF3L and EIF3M.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
messages: Cytoplasm

219594:NOS1
gene id: 219594:NOS1
uniprot id: A0A6J3DWV0
uniprot id: A0A6J3DZ59
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NOS family.
messages: dendritic spine
messages: sarcolemma

219594:LOC116487563
gene id: 219594:LOC116487563
uniprot id: A0A6J3CU54
names: Similarity
messages: Belongs to the GST superfamily. Alpha family.

219594:MDK
gene id: 219594:MDK
uniprot id: A0A6J3D2Q0
names: Similarity
messages: Belongs to the pleiotrophin family.

219594:LOC116494670
gene id: 219594:LOC116494670
uniprot id: A0A6J3DRG2
names: Subcellular Location Annotation
messages: Secreted

219594:LOC116501902
gene id: 219594:LOC116501902
uniprot id: A0A6J3ENF6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

219594:WNT4
gene id: 219594:WNT4
uniprot id: A0A6J3E2N8
uniprot id: A0A6J3E7H4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

219594:FMNL1
gene id: 219594:FMNL1
uniprot id: A0A6J3EAP4
names: Similarity
messages: Belongs to the formin homology family.

219594:EXTL1
gene id: 219594:EXTL1
uniprot id: A0A6J3E873
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 47 family.
messages: Endoplasmic reticulum membrane

219594:N4BP3
gene id: 219594:N4BP3
uniprot id: A0A6J3DQ70
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the N4BP3 family.
messages: Vesicle
messages: dendrite

219594:ADCK1
gene id: 219594:ADCK1
uniprot id: A0A6J3CZT4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. ADCK protein kinase family.
messages: Secreted

219594:LOC116499193
gene id: 219594:LOC116499193
uniprot id: A0A6J3E7T1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complexin/synaphin family.
messages: Synapse

219594:CHAT
gene id: 219594:CHAT
uniprot id: A0A6J3DCZ8
names: Similarity
messages: Belongs to the carnitine/choline acetyltransferase family.

219594:LOC116488755
gene id: 219594:LOC116488755
uniprot id: A0A6J3CYT6
names: Subcellular Location Annotation
messages: Nucleus

219594:DDX52
gene id: 219594:DDX52
uniprot id: A0A6J3E5E4
names: Domain
names: Function
names: Similarity
messages: Belongs to the DEAD box helicase family. DDX52/ROK1 subfamily.
messages: RNA helicase.
messages: The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.

219594:BMPR2
gene id: 219594:BMPR2
uniprot id: A0A6J3D3N6
names: Similarity
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.

219594:LOC116499893
gene id: 219594:LOC116499893
uniprot id: A0A6J3EAB5
names: Similarity
messages: Belongs to the intermediate filament family.

219594:ECRG4
gene id: 219594:ECRG4
uniprot id: A0A6J3DVE6
names: Similarity
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Belongs to the augurin family.
messages: Cytoplasm
messages: Membrane
messages: Secreted

219594:SEMA3F
gene id: 219594:SEMA3F
uniprot id: A0A6J3DFI9
uniprot id: A0A6J3DJH4
names: Caution
names: Similarity
messages: Belongs to the semaphorin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:MSX2
gene id: 219594:MSX2
uniprot id: A0A6J3DUN2
names: Subcellular Location Annotation
messages: Nucleus

219594:LOC116497929
gene id: 219594:LOC116497929
uniprot id: A0A6J3E936
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM45 family.
messages: Membrane

219594:HNRNPR
gene id: 219594:HNRNPR
uniprot id: A0A6J3E3W2
uniprot id: A0A6J3E8V1
names: Subcellular Location Annotation
messages: Cytoplasm

219594:UXS1
gene id: 219594:UXS1
uniprot id: A0A6J3CF02
uniprot id: A0A6J3CHW2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. UDP-glucuronic acid decarboxylase subfamily.
messages: Golgi stack membrane
messages: Membrane

219594:GALNT17
gene id: 219594:GALNT17
uniprot id: A0A6J3E443
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
messages: Golgi apparatus membrane
messages: Membrane

219594:SLC25A5
gene id: 219594:SLC25A5
uniprot id: A0A6J3DKF3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Catalyzes the exchange of ADP and ATP across the membrane.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Monomer.

219594:LOC116490280
gene id: 219594:LOC116490280
uniprot id: A0A6J3D6M2
names: Caution
names: Cofactor
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:COL4A6
gene id: 219594:COL4A6
uniprot id: A0A6J3DNG8
uniprot id: A0A6J3DQA5
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Type IV collagen is the major structural component of glomerular basement membranes (GBM), forming a 'chicken-wire' meshwork together with laminins, proteoglycans and entactin/nidogen.
messages: basement membrane

219594:SUGT1
gene id: 219594:SUGT1
uniprot id: A0A6J3ENS8
names: Similarity
messages: Belongs to the SGT1 family.

219594:NUF2
gene id: 219594:NUF2
uniprot id: A0A6J3DFN0
names: Similarity
messages: Belongs to the NUF2 family.

219594:MYO6
gene id: 219594:MYO6
uniprot id: A0A6J3CM35
uniprot id: A0A6J3CM39
uniprot id: A0A6J3CNU6
uniprot id: A0A6J3CNV1
uniprot id: A0A6J3CPR2
uniprot id: A0A6J3CS07
uniprot id: A0A6J3CT44
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
messages: clathrin-coated pit
messages: clathrin-coated vesicle
messages: filopodium
messages: microvillus
messages: ruffle membrane
messages: trans-Golgi network membrane

219594:YAE1
gene id: 219594:YAE1
uniprot id: A0A6J3CJY0
uniprot id: A0A6J3CN30
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

219594:COX3
gene id: 219594:COX3
uniprot id: A0A068L8T9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)). The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
messages: Membrane

219594:TMEM138
gene id: 219594:TMEM138
uniprot id: A0A6J3D638
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM138 family.
messages: Membrane
messages: Required for ciliogenesis.
messages: Vacuole membrane
messages: cilium

219594:COL4A5
gene id: 219594:COL4A5
uniprot id: A0A6J3DLT9
uniprot id: A0A6J3DP52
uniprot id: A0A6J3DR31
uniprot id: A0A6J3DS17
uniprot id: A0A6J3DT27
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Type IV collagen is the major structural component of glomerular basement membranes (GBM), forming a 'chicken-wire' meshwork together with laminins, proteoglycans and entactin/nidogen.
messages: basement membrane

219594:PARP1
gene id: 219594:PARP1
uniprot id: A0A6J3CQ92
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ARTD/PARP family.
messages: Chromosome
messages: Nucleus
messages: Poly-ADP-ribosyltransferase that mediates poly-ADP-ribosylation of proteins and plays a key role in DNA repair.

219594:NRXN1
gene id: 219594:NRXN1
uniprot id: A0A6J3CQY9
uniprot id: A0A6J3CQZ5
uniprot id: A0A6J3CQZ8
uniprot id: A0A6J3CR07
uniprot id: A0A6J3CT90
uniprot id: A0A6J3CT95
uniprot id: A0A6J3CTA0
uniprot id: A0A6J3CTA2
uniprot id: A0A6J3CTA7
uniprot id: A0A6J3CTQ6
uniprot id: A0A6J3CTQ8
uniprot id: A0A6J3CTR3
uniprot id: A0A6J3CTR8
uniprot id: A0A6J3CTS3
uniprot id: A0A6J3CW06
uniprot id: A0A6J3CW11
uniprot id: A0A6J3CW16
uniprot id: A0A6J3CW21
uniprot id: A0A6J3CX47
uniprot id: A0A6J3CX51
uniprot id: A0A6J3CX58
uniprot id: A0A6J3CX62
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the neurexin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

219594:LOC116499135
gene id: 219594:LOC116499135
uniprot id: A0A6J3EEC2
names: Similarity
messages: Belongs to the HARBI1 family.

219594:LOC116488528
gene id: 219594:LOC116488528
uniprot id: A0A6J3CXM3
names: Subcellular Location Annotation
messages: Membrane

219594:BID
gene id: 219594:BID
uniprot id: A0A6J3DKC4
names: Domain
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Forms heterodimers either with the pro-apoptotic protein BAX or the anti-apoptotic protein BCL2.
messages: Induces caspases and apoptosis. Counters the protective effect of BCL2.
messages: Intact BH3 motif is required by BIK, BID, BAK, BAD and BAX for their pro-apoptotic activity and for their interaction with anti-apoptotic members of the Bcl-2 family.
messages: Membrane
messages: Mitochondrion outer membrane

219594:SAP130
gene id: 219594:SAP130
uniprot id: A0A6J3DFM8
uniprot id: A0A6J3DJ24
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SAP130 family.
messages: Nucleus

219594:MYO3B
gene id: 219594:MYO3B
uniprot id: A0A6J3D8R0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
messages: In the C-terminal section; belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
messages: cytoskeleton

219594:ADGRA1
gene id: 219594:ADGRA1
uniprot id: A0A6J3D601
uniprot id: A0A6J3D8P7
uniprot id: A0A6J3DBE4
uniprot id: A0A6J3DBW4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 2 family. Adhesion G-protein coupled receptor (ADGR) subfamily.
messages: Membrane

219594:AMDHD2
gene id: 219594:AMDHD2
uniprot id: A0A6J3DQN6
names: Cofactor
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. NagA family.
messages: Binds 1 divalent metal cation per subunit.

219594:PPP1R16B
gene id: 219594:PPP1R16B
uniprot id: A0A6J3DW27
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

219594:CWC25
gene id: 219594:CWC25
uniprot id: A0A6J3EB26
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CWC25 family.
messages: Nucleus

219594:HMGA2
gene id: 219594:HMGA2
uniprot id: A0A6J3EHU2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HMGA family.
messages: Nucleus

219594:SIRT4
gene id: 219594:SIRT4
uniprot id: A0A6J3DX30
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sirtuin family. Class II subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Mitochondrion matrix
messages: NAD-dependent protein deacylase. Catalyzes the NAD-dependent hydrolysis of acyl groups from lysine residues.

219594:ATP6V1C2
gene id: 219594:ATP6V1C2
uniprot id: A0A6J3CS43
names: Function
names: Similarity
names: Subunit
messages: Belongs to the V-ATPase C subunit family.
messages: Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment. Subunit C is necessary for the assembly of the catalytic sector of the enzyme and is likely to have a specific function in its catalytic activity.
messages: V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex. The V1 complex consists of three catalytic AB heterodimers that form a heterohexamer, three peripheral stalks each consisting of EG heterodimers, one central rotor including subunits D and F, and the regulatory subunits C and H. The proton translocation complex V0 consists of the proton transport subunit a, a ring of proteolipid subunits c9c'', rotary subunit d, subunits e and f, and two accessory subunits.

219594:PPEF2
gene id: 219594:PPEF2
uniprot id: A0A6J3CVS5
names: Similarity
messages: Belongs to the PPP phosphatase family.

219594:RNASET2
gene id: 219594:RNASET2
uniprot id: A0A6J3CPE8
uniprot id: A0A6J3CVI2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase T2 family.
messages: Lysosome lumen

219594:NUBPL
gene id: 219594:NUBPL
uniprot id: A0A6J3CZF6
names: Similarity
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.

219594:SLC12A2
gene id: 219594:SLC12A2
uniprot id: A0A6J3EGP6
uniprot id: A0A6J3ELY5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC12A transporter family.
messages: Membrane

219594:LIN28B
gene id: 219594:LIN28B
uniprot id: A0A6J3CRA3
uniprot id: A0A6J3CRY3
uniprot id: A0A6J3CUA0
uniprot id: A0A6J3CVD9
names: Similarity
messages: Belongs to the lin-28 family.

219594:LOC116501332
gene id: 219594:LOC116501332
uniprot id: A0A6J3ELG0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

219594:LOC116499260
gene id: 219594:LOC116499260
uniprot id: A0A6J3ED51
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the immunoglobulin superfamily. BTN/MOG family.
messages: Membrane

219594:LOC116496164
gene id: 219594:LOC116496164
uniprot id: A0A6J3DUD0
names: Subcellular Location Annotation
messages: Membrane

219594:LOC116494089
gene id: 219594:LOC116494089
uniprot id: A0A6J3DQ50
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm

219594:MYO16
gene id: 219594:MYO16
uniprot id: A0A6J3CRY6
uniprot id: A0A6J3CUS9
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.

219594:LOC116495354
gene id: 219594:LOC116495354
uniprot id: A0A6J3DWG4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

219594:NKX2-2
gene id: 219594:NKX2-2
uniprot id: A0A6J3CVR1
names: Subcellular Location Annotation
messages: Nucleus

219594:KIF21A
gene id: 219594:KIF21A
uniprot id: A0A6J3DBT9
uniprot id: A0A6J3DBU9
uniprot id: A0A6J3DBV7
uniprot id: A0A6J3DEE3
uniprot id: A0A6J3DEJ3
uniprot id: A0A6J3DFQ0
uniprot id: A0A6J3DHV6
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

219594:TATDN3
gene id: 219594:TATDN3
uniprot id: A0A6J3CNU8
uniprot id: A0A6J3CQS9
uniprot id: A0A6J3CRI1
uniprot id: A0A6J3CTS5
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. TatD-type hydrolase family.

219594:PIGK
gene id: 219594:PIGK
uniprot id: A0A6J3DGJ8
uniprot id: A0A6J3DGS5
names: Similarity
names: Subunit
messages: Belongs to the peptidase C13 family.
messages: Forms a complex with PIGT, PIGS, PIGU and GAA1.

219594:PLXNA4
gene id: 219594:PLXNA4
uniprot id: A0A6J3E8Y1
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the plexin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

219594:GCG
gene id: 219594:GCG
uniprot id: A0A6J3DAJ1
names: Similarity
messages: Belongs to the glucagon family.

219594:FUT8
gene id: 219594:FUT8
uniprot id: A0A6J3D3M1
uniprot id: A0A6J3D3Z1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 23 family.
messages: Catalyzes the addition of fucose in alpha 1-6 linkage to the first GlcNAc residue, next to the peptide chains in N-glycans.
messages: Golgi stack membrane
messages: Membrane

219594:EIF1AX
gene id: 219594:EIF1AX
uniprot id: A0A6J3DVE9
names: Function
names: Similarity
messages: Belongs to the eIF-1A family.
messages: Component of the 43S pre-initiation complex (43S PIC), which binds to the mRNA cap-proximal region, scans mRNA 5'-untranslated region, and locates the initiation codon. This protein enhances formation of the cap-proximal complex. Together with EIF1, facilitates scanning, start codon recognition, promotion of the assembly of 48S complex at the initiation codon (43S PIC becomes 48S PIC after the start codon is reached), and dissociation of aberrant complexes. After start codon location, together with EIF5B orients the initiator methionine-tRNA in a conformation that allows 60S ribosomal subunit joining to form the 80S initiation complex. Is released after 80S initiation complex formation, just after GTP hydrolysis by EIF5B, and before release of EIF5B. Its globular part is located in the A site of the 40S ribosomal subunit. Its interaction with EIF5 during scanning contribute to the maintenance of EIF1 within the open 43S PIC. In contrast to yeast orthologs, does not bind EIF1.

219594:TRIAP1
gene id: 219594:TRIAP1
uniprot id: A0A6J3E133
names: Similarity
messages: Belongs to the TRIAP1/MDM35 family.

219594:TBX4
gene id: 219594:TBX4
uniprot id: A0A6J3E6B4
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

219594:FAM219A
gene id: 219594:FAM219A
uniprot id: A0A6J3EIH8
uniprot id: A0A6J3EIW0
uniprot id: A0A6J3EKG1
names: Similarity
messages: Belongs to the FAM219 family.

219594:GPLD1
gene id: 219594:GPLD1
uniprot id: A0A6J3CLC5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPLD1 family.
messages: Secreted

219594:HOPX
gene id: 219594:HOPX
uniprot id: A0A6J3CU27
uniprot id: A0A6J3CWC6
names: Subcellular Location Annotation
messages: Nucleus

219594:FGF10
gene id: 219594:FGF10
uniprot id: A0A6J3EDP4
uniprot id: A0A6J3EIX5
names: Similarity
messages: Belongs to the heparin-binding growth factors family.

219594:TUBG1
gene id: 219594:TUBG1
uniprot id: A0A6J3E6R6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Tubulin is the major constituent of microtubules. The gamma chain is found at microtubule organizing centers (MTOC) such as the spindle poles or the centrosome.
messages: cytoskeleton

219594:SLC44A2
gene id: 219594:SLC44A2
uniprot id: A0A6J3EB25
uniprot id: A0A6J3EFT5
uniprot id: A0A6J3EHR0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CTL (choline transporter-like) family.
messages: Cell membrane
messages: Choline transporter.
messages: Membrane

219594:SFTPC
gene id: 219594:SFTPC
uniprot id: A0A6J3EDM9
uniprot id: A0A6J3EFC5
names: Function
names: Subcellular Location Annotation
messages: Pulmonary surfactant associated proteins promote alveolar stability by lowering the surface tension at the air-liquid interface in the peripheral air spaces.
messages: surface film

219594:CENPA
gene id: 219594:CENPA
uniprot id: A0A6J3EBG8
names: Similarity
messages: Belongs to the histone H3 family.

219594:RIOK3
gene id: 219594:RIOK3
uniprot id: A0A6J3CJL5
names: Similarity
messages: Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family.

219594:ATP6V0B
gene id: 219594:ATP6V0B
uniprot id: A0A6J3DCC1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the V-ATPase proteolipid subunit family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Proton-conducting pore forming of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment.
messages: V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex. The V1 complex consists of three catalytic AB heterodimers that form a heterohexamer, three peripheral stalks each consisting of EG heterodimers, one central rotor including subunits D and F, and the regulatory subunits C and H. The proton translocation complex V0 consists of the proton transport subunit a, a ring of proteolipid subunits c9c'', rotary subunit d, subunits e and f, and the accessory subunits.
messages: clathrin-coated vesicle membrane

219594:BTK
gene id: 219594:BTK
uniprot id: A0A6J3DL03
names: Similarity
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.

219594:LOC116501995
gene id: 219594:LOC116501995
uniprot id: A0A6J3ENU8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L6 tetraspanin family.
messages: Membrane

219594:CHD4
gene id: 219594:CHD4
uniprot id: A0A6J3EJC4
uniprot id: A0A6J3EKP2
uniprot id: A0A6J3EPM8
uniprot id: A0A6J3EPP9
uniprot id: A0A6J3ER34
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNF2/RAD54 helicase family.
messages: Nucleus

219594:FSTL4
gene id: 219594:FSTL4
uniprot id: A0A6J3DPH7
uniprot id: A0A6J3DRI7
names: Subcellular Location Annotation
messages: Secreted

219594:MAP2K6
gene id: 219594:MAP2K6
uniprot id: A0A6J3DVS6
names: Similarity
messages: Belongs to the protein kinase superfamily.

219594:ARRDC2
gene id: 219594:ARRDC2
uniprot id: A0A6J3E798
names: Similarity
messages: Belongs to the arrestin family.

219594:LOC116501343
gene id: 219594:LOC116501343
uniprot id: A0A6J3ELH0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

219594:EMC7
gene id: 219594:EMC7
uniprot id: A0A6J3D2L7
names: Similarity
names: Subunit
messages: Belongs to the EMC7 family.
messages: Component of the ER membrane protein complex (EMC).

219594:LOC116500260
gene id: 219594:LOC116500260
uniprot id: A0A6J3EBN5
uniprot id: A0A6J3ECZ0
uniprot id: A0A6J3EGD2
names: Similarity
messages: Belongs to the MHC class I family.

219594:CUL5
gene id: 219594:CUL5
uniprot id: A0A6J3DRP0
names: Similarity
messages: Belongs to the cullin family.

219594:UNC13B
gene id: 219594:UNC13B
uniprot id: A0A6J3ECP9
uniprot id: A0A6J3ECQ1
uniprot id: A0A6J3EE33
uniprot id: A0A6J3EHK7
uniprot id: A0A6J3EHU3
uniprot id: A0A6J3EHU8
uniprot id: A0A6J3EJG7
names: Subcellular Location Annotation
messages: Cytoplasm

219594:GGCX
gene id: 219594:GGCX
uniprot id: A0A6J3ECT8
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

219594:KDELR3
gene id: 219594:KDELR3
uniprot id: A0A6J3DKY7
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ERD2 family.
messages: COPI-coated vesicle membrane
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

219594:PRKD3
gene id: 219594:PRKD3
uniprot id: A0A6J3CVF8
names: Activity Regulation
names: Similarity
names: Subcellular Location Annotation
messages: Activated by DAG and phorbol esters.
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. PKD subfamily.
messages: Cytoplasm
messages: Membrane

219594:LOC116500207
gene id: 219594:LOC116500207
uniprot id: A0A6J3ECR8
uniprot id: A0A6J3EGH2
names: Subcellular Location Annotation
messages: Membrane

219594:ABCA7
gene id: 219594:ABCA7
uniprot id: A0A6J3EBX9
names: Subcellular Location Annotation
messages: Membrane

219594:RARS1
gene id: 219594:RARS1
uniprot id: A0A6J3DUC4
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

219594:SIDT2
gene id: 219594:SIDT2
uniprot id: A0A6J3E2S4
uniprot id: A0A6J3E462
uniprot id: A0A6J3E732
uniprot id: A0A6J3E7Q8
uniprot id: A0A6J3E955
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SID1 family.
messages: Membrane

219594:LEPROTL1
gene id: 219594:LEPROTL1
uniprot id: A0A6J3CUW3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OB-RGRP/VPS55 family.
messages: Membrane

219594:SLC29A4
gene id: 219594:SLC29A4
uniprot id: A0A6J3DV64
uniprot id: A0A6J3DW23
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC29A/ENT transporter (TC 2.A.57) family.
messages: Membrane

219594:TMEM255B
gene id: 219594:TMEM255B
uniprot id: A0A6J3E4P4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM255 family.
messages: Membrane

219594:LOC116487081
gene id: 219594:LOC116487081
uniprot id: A0A6J3CRS0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

219594:MTERF2
gene id: 219594:MTERF2
uniprot id: A0A6J3ERT9
names: Similarity
messages: Belongs to the mTERF family.

219594:PTPN2
gene id: 219594:PTPN2
uniprot id: A0A6J3CE32
uniprot id: A0A6J3CKA6
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class 1 subfamily.

219594:DNAH17
gene id: 219594:DNAH17
uniprot id: A0A6J3DZY1
names: Similarity
messages: Belongs to the dynein heavy chain family.

219594:ACAN
gene id: 219594:ACAN
uniprot id: A0A6J3DNP5
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

219594:PUS1
gene id: 219594:PUS1
uniprot id: A0A6J3DYT3
names: Similarity
messages: Belongs to the tRNA pseudouridine synthase TruA family.

219594:LOC116494205
gene id: 219594:LOC116494205
uniprot id: A0A6J3DPE9
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

219594:IGF2R
gene id: 219594:IGF2R
uniprot id: A0A6J3CPS9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:CACNA1D
gene id: 219594:CACNA1D
uniprot id: A0A6J3DKX0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. CACNA1D subfamily.
messages: Membrane
messages: Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death.

219594:SLIT2
gene id: 219594:SLIT2
uniprot id: A0A6J3CVK5
uniprot id: A0A6J3CVL0
uniprot id: A0A6J3CVL5
uniprot id: A0A6J3CXV2
uniprot id: A0A6J3CXV8
uniprot id: A0A6J3CXW5
uniprot id: A0A6J3CY76
uniprot id: A0A6J3CY81
uniprot id: A0A6J3CY84
uniprot id: A0A6J3D0G8
uniprot id: A0A6J3D0H3
uniprot id: A0A6J3D0H8
uniprot id: A0A6J3D1M1
uniprot id: A0A6J3D1N2
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

219594:TLX2
gene id: 219594:TLX2
uniprot id: A0A6J3D1W6
names: Subcellular Location Annotation
messages: Nucleus

219594:LOC116497197
gene id: 219594:LOC116497197
uniprot id: A0A6J3DZB1
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

219594:LOC116493119
gene id: 219594:LOC116493119
uniprot id: A0A6J3DLB6
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: basement membrane

219594:SNX30
gene id: 219594:SNX30
uniprot id: A0A6J3EIN9
names: Similarity
messages: Belongs to the sorting nexin family.

219594:FAM151B
gene id: 219594:FAM151B
uniprot id: A0A6J3EK01
names: Similarity
messages: Belongs to the FAM151 family.

219594:LOC116499742
gene id: 219594:LOC116499742
uniprot id: A0A6J3E9U3
names: Similarity
names: Subunit
messages: Belongs to the avian keratin family.
messages: The avian keratins (F-ker, S-ker, C-ker and B-ker) are a complex mixture of very similar polypeptides.

219594:SLC39A6
gene id: 219594:SLC39A6
uniprot id: A0A6J3CFN3
uniprot id: A0A6J3CGM4
names: Subcellular Location Annotation
messages: Membrane

219594:ARRDC1
gene id: 219594:ARRDC1
uniprot id: A0A6J3DY15
names: Similarity
messages: Belongs to the arrestin family.

219594:XYLT2
gene id: 219594:XYLT2
uniprot id: A0A6J3DWN7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycosyltransferase 14 family. XylT subfamily.
messages: Golgi apparatus membrane
messages: Membrane
messages: Monomer.

219594:RBP2
gene id: 219594:RBP2
uniprot id: A0A6J3DDA5
names: Similarity
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.

219594:SETD2
gene id: 219594:SETD2
uniprot id: A0A6J3CFQ0
names: Subcellular Location Annotation
messages: Nucleus

219594:EPN3
gene id: 219594:EPN3
uniprot id: A0A6J3E153
uniprot id: A0A6J3E1Y1
uniprot id: A0A6J3E337
names: Similarity
messages: Belongs to the epsin family.

219594:CDPF1
gene id: 219594:CDPF1
uniprot id: A0A6J3E6R1
uniprot id: A0A6J3E9Q9
names: Similarity
messages: Belongs to the CDPF1 family.

219594:PTPRT
gene id: 219594:PTPRT
uniprot id: A0A6J3DRI0
uniprot id: A0A6J3DRI5
uniprot id: A0A6J3DTP6
uniprot id: A0A6J3DTQ0
uniprot id: A0A6J3DVV2
uniprot id: A0A6J3DVV8
uniprot id: A0A6J3DWP3
uniprot id: A0A6J3DXN5
uniprot id: A0A6J3DXP0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Receptor class 2B subfamily.
messages: Membrane

219594:C6H2orf76
gene id: 219594:C6H2orf76
uniprot id: A0A6J3D6R3
names: Similarity
messages: Belongs to the UPF0538 family.

219594:OVCH2
gene id: 219594:OVCH2
uniprot id: A0A6J3DEQ6
uniprot id: A0A6J3DHF7
uniprot id: A0A6J3DKB3
uniprot id: A0A6J3DKV9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:CHURC1
gene id: 219594:CHURC1
uniprot id: A0A6J3D705
names: Similarity
messages: Belongs to the Churchill family.

219594:LOC116485553
gene id: 219594:LOC116485553
uniprot id: A0A6J3CD69
uniprot id: A0A6J3CJF7
names: Similarity
messages: Belongs to the protein kinase superfamily.
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family.

219594:PFKFB4
gene id: 219594:PFKFB4
uniprot id: A0A6J3DH30
uniprot id: A0A6J3DIC0
uniprot id: A0A6J3DJX8
uniprot id: A0A6J3DKG6
names: Similarity
messages: In the C-terminal section; belongs to the phosphoglycerate mutase family.

219594:KIF21B
gene id: 219594:KIF21B
uniprot id: A0A6J3E6H9
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

219594:LOC116494355
gene id: 219594:LOC116494355
uniprot id: A0A6J3DR83
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase VIIb family.
messages: Membrane
messages: Mitochondrion inner membrane

219594:GPR25
gene id: 219594:GPR25
uniprot id: A0A6J3E6Z4
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

219594:PBRM1
gene id: 219594:PBRM1
uniprot id: A0A6J3DE15
uniprot id: A0A6J3DE21
uniprot id: A0A6J3DGS7
uniprot id: A0A6J3DGT6
uniprot id: A0A6J3DI06
uniprot id: A0A6J3DI11
uniprot id: A0A6J3DI16
uniprot id: A0A6J3DJN1
uniprot id: A0A6J3DJN6
uniprot id: A0A6J3DK54
names: Subcellular Location Annotation
messages: Nucleus

219594:NR5A1
gene id: 219594:NR5A1
uniprot id: A0A6J3DZU1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR5 subfamily.
messages: Nucleus

219594:LOC116494080
gene id: 219594:LOC116494080
uniprot id: A0A6J3DM62
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:NDUFS7
gene id: 219594:NDUFS7
uniprot id: A0A6J3EBQ2
names: Similarity
messages: Belongs to the complex I 20 kDa subunit family.

219594:STT3A
gene id: 219594:STT3A
uniprot id: A0A6J3E8X2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STT3 family.
messages: Membrane

219594:TCIRG1
gene id: 219594:TCIRG1
uniprot id: A0A6J3D122
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the V-ATPase 116 kDa subunit family.
messages: Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.
messages: Membrane

219594:GPHN
gene id: 219594:GPHN
uniprot id: A0A6J3CY34
uniprot id: A0A6J3CY38
uniprot id: A0A6J3CY42
uniprot id: A0A6J3D0K0
uniprot id: A0A6J3D0K4
uniprot id: A0A6J3D0L0
uniprot id: A0A6J3D0M1
uniprot id: A0A6J3D0M6
uniprot id: A0A6J3D0N1
uniprot id: A0A6J3D309
uniprot id: A0A6J3D312
uniprot id: A0A6J3D316
uniprot id: A0A6J3D432
uniprot id: A0A6J3D437
uniprot id: A0A6J3D441
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes two steps in the biosynthesis of the molybdenum cofactor. In the first step, molybdopterin is adenylated. Subsequently, molybdate is inserted into adenylated molybdopterin and AMP is released.
messages: In the C-terminal section; belongs to the MoeA family.
messages: In the N-terminal section; belongs to the MoaB/Mog family.

219594:COX1
gene id: 219594:COX1
uniprot id: A0A068L9A8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)). The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
messages: Membrane
messages: Mitochondrion inner membrane

219594:OVCH1
gene id: 219594:OVCH1
uniprot id: A0A6J3CLY6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:HEATR1
gene id: 219594:HEATR1
uniprot id: A0A6J3CSM0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HEATR1/UTP10 family.
messages: Involved in nucleolar processing of pre-18S ribosomal RNA.
messages: nucleolus

219594:MEX3D
gene id: 219594:MEX3D
uniprot id: A0A6J3ECK9
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

219594:SYNGR2
gene id: 219594:SYNGR2
uniprot id: A0A6J3E1D7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptogyrin family.
messages: Membrane

219594:LOC116490327
gene id: 219594:LOC116490327
uniprot id: A0A6J3D6W5
uniprot id: A0A6J3D7Q9
names: Similarity
messages: Belongs to the MS4A family.

219594:LOC116485391
gene id: 219594:LOC116485391
uniprot id: A0A6J3CC57
names: Similarity
names: Subunit
messages: Belongs to the avian keratin family.
messages: The avian keratins (F-ker, S-ker, C-ker and B-ker) are a complex mixture of very similar polypeptides.

219594:DDI2
gene id: 219594:DDI2
uniprot id: A0A6J3E860
names: Similarity
messages: Belongs to the DDI1 family.

219594:RRM2
gene id: 219594:RRM2
uniprot id: A0A6J3CUN8
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.

219594:PAQR7
gene id: 219594:PAQR7
uniprot id: A0A6J3E8F9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ADIPOR family.
messages: Membrane

219594:PLOD2
gene id: 219594:PLOD2
uniprot id: A0A6J3DC26
uniprot id: A0A6J3DHK0
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane

219594:LOC116496467
gene id: 219594:LOC116496467
uniprot id: A0A6J3DZY8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CYBC1 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

219594:SLC25A28
gene id: 219594:SLC25A28
uniprot id: A0A6J3DBT7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

219594:DCLK2
gene id: 219594:DCLK2
uniprot id: A0A6J3CUK6
uniprot id: A0A6J3CV21
uniprot id: A0A6J3CXC4
uniprot id: A0A6J3CYG4
names: Similarity
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. CaMK subfamily.

219594:STK11IP
gene id: 219594:STK11IP
uniprot id: A0A6J3DAH2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STK11IP family.
messages: Cytoplasm

219594:PRKACB
gene id: 219594:PRKACB
uniprot id: A0A6J3DBM0
uniprot id: A0A6J3DEK1
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. cAMP subfamily.

219594:CGAS
gene id: 219594:CGAS
uniprot id: A0A6J3CQI1
names: Similarity
messages: Belongs to the mab-21 family.

219594:HTR1D
gene id: 219594:HTR1D
uniprot id: A0A6J3EA52
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

219594:GNA11
gene id: 219594:GNA11
uniprot id: A0A6J3EDN3
names: Similarity
messages: Belongs to the G-alpha family. G(q) subfamily.

219594:ESS2
gene id: 219594:ESS2
uniprot id: A0A6J3E0X9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ESS2 family.
messages: Nucleus

219594:P2RY1
gene id: 219594:P2RY1
uniprot id: A0A6J3DEQ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

219594:LOC116495205
gene id: 219594:LOC116495205
uniprot id: A0A6J3DTY3
names: Caution
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:SLC37A1
gene id: 219594:SLC37A1
uniprot id: A0A6J3EHU5
uniprot id: A0A6J3EN24
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Organophosphate:Pi antiporter (OPA) (TC 2.A.1.4) family.
messages: Membrane

219594:LOC116489096
gene id: 219594:LOC116489096
uniprot id: A0A6J3D1J4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Opsin subfamily.
messages: Membrane

219594:NLGN3
gene id: 219594:NLGN3
uniprot id: A0A6J3DKT1
uniprot id: A0A6J3DN94
uniprot id: A0A6J3DQ18
uniprot id: A0A6J3DR76
uniprot id: A0A6J3DS44
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type-B carboxylesterase/lipase family.
messages: Cell membrane
messages: Membrane

219594:SURF6
gene id: 219594:SURF6
uniprot id: A0A6J3E2K7
names: Similarity
messages: Belongs to the SURF6 family.

219594:TMEM106A
gene id: 219594:TMEM106A
uniprot id: A0A6J3EAQ2
names: Similarity
messages: Belongs to the TMEM106 family.

219594:LOC116496791
gene id: 219594:LOC116496791
uniprot id: A0A6J3DX66
uniprot id: A0A6J3E263
names: Subcellular Location Annotation
messages: Membrane

219594:DSCC1
gene id: 219594:DSCC1
uniprot id: A0A6J3CIY2
names: Similarity
messages: Belongs to the DCC1 family.

219594:CLSTN1
gene id: 219594:CLSTN1
uniprot id: A0A6J3E1Q9
uniprot id: A0A6J3E318
uniprot id: A0A6J3E5Z0
uniprot id: A0A6J3E7Y7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calsyntenin family.
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Postsynaptic cell membrane

219594:BLMH
gene id: 219594:BLMH
uniprot id: A0A6J3DZT1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C1 family.
messages: Cytoplasm

219594:SUSD2
gene id: 219594:SUSD2
uniprot id: A0A6J3DXA5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:NTSR1
gene id: 219594:NTSR1
uniprot id: A0A6J3DUQ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

219594:SLA
gene id: 219594:SLA
uniprot id: A0A6J3CIA8
names: Subcellular Location Annotation
messages: Cytoplasm

219594:LOC116485681
gene id: 219594:LOC116485681
uniprot id: A0A6J3CI22
names: Similarity
names: Subunit
messages: Belongs to the avian keratin family.
messages: The avian keratins (F-ker, S-ker, C-ker and B-ker) are a complex mixture of very similar polypeptides.

219594:SLC7A11
gene id: 219594:SLC7A11
uniprot id: A0A6J3D1E3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. L-type amino acid transporter (LAT) (TC 2.A.3.8) family.
messages: Cell membrane
messages: Membrane

219594:NDUFB9
gene id: 219594:NDUFB9
uniprot id: A0A6J3CCX6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed to be not involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I LYR family.
messages: Mammalian complex I is composed of 45 different subunits.
messages: Mitochondrion inner membrane

219594:METTL14
gene id: 219594:METTL14
uniprot id: A0A6J3CXA4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MT-A70-like family.
messages: Heterodimer; heterodimerizes with mettl3 to form an antiparallel heterodimer that constitutes an active methyltransferase.
messages: Nucleus
messages: The METTL3-METTL14 heterodimer forms a N6-methyltransferase complex that methylates adenosine residues at the N(6) position of some mRNAs and regulates the circadian clock, differentiation of embryonic stem cells and cortical neurogenesis. In the heterodimer formed with mettl3, mettl14 constitutes the RNA-binding scaffold that recognizes the substrate rather than the catalytic core. N6-methyladenosine (m6A), which takes place at the 5'-[AG]GAC-3' consensus sites of some mRNAs, plays a role in mRNA stability and processing.

219594:HEXIM1
gene id: 219594:HEXIM1
uniprot id: A0A6J3E499
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HEXIM family.
messages: Nucleus

219594:ME1
gene id: 219594:ME1
uniprot id: A0A6J3CP18
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

219594:APLP2
gene id: 219594:APLP2
uniprot id: A0A6J3E2S9
uniprot id: A0A6J3E2T4
uniprot id: A0A6J3E468
uniprot id: A0A6J3E741
uniprot id: A0A6J3E7S0
uniprot id: A0A6J3E964
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the APP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

219594:MTFR2
gene id: 219594:MTFR2
uniprot id: A0A6J3CPR9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MTFR1 family.
messages: Mitochondrion
messages: Plays a role in mitochondrial aerobic respiration. Regulates mitochondrial organization and fission.

219594:TNFRSF9
gene id: 219594:TNFRSF9
uniprot id: A0A6J3E391
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:LOC116497121
gene id: 219594:LOC116497121
uniprot id: A0A6J3E516
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2A family.
messages: Chromosome
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

219594:TLCD3A
gene id: 219594:TLCD3A
uniprot id: A0A6J3E4W3
names: Subcellular Location Annotation
messages: Membrane

219594:ST3GAL1
gene id: 219594:ST3GAL1
uniprot id: A0A6J3CIN3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

219594:LMOD3
gene id: 219594:LMOD3
uniprot id: A0A6J3DL94
names: Subcellular Location Annotation
messages: cytoskeleton
messages: sarcomere

219594:QSOX1
gene id: 219594:QSOX1
uniprot id: A0A6J3DGN1
names: Function
names: Similarity
messages: Belongs to the quiescin-sulfhydryl oxidase (QSOX) family.
messages: Catalyzes the oxidation of sulfhydryl groups in peptide and protein thiols to disulfides with the reduction of oxygen to hydrogen peroxide.

219594:CREG1
gene id: 219594:CREG1
uniprot id: A0A6J3ENP2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CREG family.
messages: Secreted

219594:SEBOX
gene id: 219594:SEBOX
uniprot id: A0A6J3E0B9
names: Subcellular Location Annotation
messages: Nucleus

219594:LOC116487934
gene id: 219594:LOC116487934
uniprot id: A0A6J3CUW1
names: Similarity
names: Subcellular Location Annotation
messages: Basolateral cell membrane
messages: Belongs to the potassium channel family. KQT (TC 1.A.1.15) subfamily. Kv7.1/KCNQ1 sub-subfamily.
messages: Cell membrane
messages: Cytoplasmic vesicle membrane
messages: Endoplasmic reticulum
messages: Lateral cell membrane
messages: Membrane
messages: Membrane raft

219594:ELOVL6
gene id: 219594:ELOVL6
uniprot id: A0A6J3D1H4
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELO family. ELOVL6 subfamily.
messages: Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that elongates fatty acids with 12, 14 and 16 carbons with higher activity toward C16:0 acyl-CoAs. Catalyzes the synthesis of unsaturated C16 long chain fatty acids and, to a lesser extent, C18:0 and those with low desaturation degree. May participate to the production of saturated and monounsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: N-Glycosylated.

219594:ATP4B
gene id: 219594:ATP4B
uniprot id: A0A6J3EQS7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the X(+)/potassium ATPases subunit beta family.
messages: Membrane
messages: This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane.

219594:BCAN
gene id: 219594:BCAN
uniprot id: A0A6J3EE61
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:PEX10
gene id: 219594:PEX10
uniprot id: A0A6J3E208
uniprot id: A0A6J3E6Q4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pex2/pex10/pex12 family.
messages: Membrane
messages: Peroxisome membrane

219594:PRDM6
gene id: 219594:PRDM6
uniprot id: A0A6J3EF98
names: Subcellular Location Annotation
messages: Nucleus

219594:TUBE1
gene id: 219594:TUBE1
uniprot id: A0A6J3CPM5
uniprot id: A0A6J3CVQ6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: cytoskeleton

219594:OST4
gene id: 219594:OST4
uniprot id: A0A6J3CVK6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OST4 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

219594:SOGA1
gene id: 219594:SOGA1
uniprot id: A0A6J3DUM8
names: Similarity
messages: Belongs to the SOGA family.

219594:HCN4
gene id: 219594:HCN4
uniprot id: A0A6J3DL86
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the potassium channel HCN family.
messages: Cell membrane
messages: Membrane

219594:NSUN5
gene id: 219594:NSUN5
uniprot id: A0A6J3DZF9
names: Caution
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:CNOT2
gene id: 219594:CNOT2
uniprot id: A0A6J3DJS9
names: Similarity
messages: Belongs to the CNOT2/3/5 family.

219594:HCN2
gene id: 219594:HCN2
uniprot id: A0A6J3E7X6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the potassium channel HCN family.
messages: Cell membrane
messages: Membrane

219594:OXSR1
gene id: 219594:OXSR1
uniprot id: A0A6J3CIV4
names: Similarity
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.

219594:ISL1
gene id: 219594:ISL1
uniprot id: A0A6J3EFB9
uniprot id: A0A6J3EIR6
names: Subcellular Location Annotation
messages: Nucleus

219594:LOC116486601
gene id: 219594:LOC116486601
uniprot id: A0A6J3CPQ1
names: Similarity
names: Subunit
messages: Belongs to the avian keratin family.
messages: The avian keratins (F-ker, S-ker, C-ker and B-ker) are a complex mixture of very similar polypeptides.

219594:PRPF19
gene id: 219594:PRPF19
uniprot id: A0A6J3D3W2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the WD repeat PRP19 family.
messages: Homotetramer.
messages: Lipid droplet
messages: Ubiquitin-protein ligase which is mainly involved pre-mRNA splicing and DNA repair. Required for pre-mRNA splicing as component of the spliceosome.
messages: nucleoplasm

219594:LOC116499668
gene id: 219594:LOC116499668
uniprot id: A0A6J3E9H2
names: Similarity
names: Subunit
messages: Belongs to the avian keratin family.
messages: The avian keratins (F-ker, S-ker, C-ker and B-ker) are a complex mixture of very similar polypeptides.

219594:CELSR1
gene id: 219594:CELSR1
uniprot id: A0A6J3E1F6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 2 family. Adhesion G-protein coupled receptor (ADGR) subfamily.
messages: Belongs to the G-protein coupled receptor 2 family. LN-TM7 subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Receptor that may have an important role in cell/cell signaling during nervous system formation.

219594:UBE3A
gene id: 219594:UBE3A
uniprot id: A0A6J3CX95
uniprot id: A0A6J3D275
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and transfers it to its substrates.
messages: Nucleus

219594:LOC116501458
gene id: 219594:LOC116501458
uniprot id: A0A6J3EED6
uniprot id: A0A6J3EFU1
uniprot id: A0A6J3EGR7
uniprot id: A0A6J3EI99
uniprot id: A0A6J3EIA5
uniprot id: A0A6J3EIB0
uniprot id: A0A6J3EM12
uniprot id: A0A6J3EM37
uniprot id: A0A6J3ENF8
uniprot id: A0A6J3ENG3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tropomyosin family.
messages: cytoskeleton

219594:ZFHX3
gene id: 219594:ZFHX3
uniprot id: A0A6J3DL50
uniprot id: A0A6J3DP35
names: Subcellular Location Annotation
messages: Nucleus

219594:CPPED1
gene id: 219594:CPPED1
uniprot id: A0A6J3DRU0
uniprot id: A0A6J3DTV2
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. CPPED1 family.

219594:TCP11
gene id: 219594:TCP11
uniprot id: A0A6J3EC44
names: Similarity
messages: Belongs to the TCP11 family.

219594:MTG2
gene id: 219594:MTG2
uniprot id: A0A6J3DX22
names: Similarity
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.

219594:EIF2D
gene id: 219594:EIF2D
uniprot id: A0A6J3EAP7
uniprot id: A0A6J3ECV7
names: Similarity
messages: Belongs to the eIF2D family.

219594:RHOT1
gene id: 219594:RHOT1
uniprot id: A0A6J3DVR3
uniprot id: A0A6J3DZX1
uniprot id: A0A6J3E0Q7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial Rho GTPase family.
messages: Membrane
messages: Mitochondrial GTPase involved in mitochondrial trafficking.
messages: Mitochondrion outer membrane

219594:ME2
gene id: 219594:ME2
uniprot id: A0A6J3ED57
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

219594:TCP11L2
gene id: 219594:TCP11L2
uniprot id: A0A6J3E563
uniprot id: A0A6J3E604
names: Similarity
messages: Belongs to the TCP11 family.

219594:LOC116498906
gene id: 219594:LOC116498906
uniprot id: A0A6J3EB18
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 22 family.
messages: Secreted

219594:LOC116500114
gene id: 219594:LOC116500114
uniprot id: A0A6J3EFW3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

219594:LOC116488292
gene id: 219594:LOC116488292
uniprot id: A0A6J3CRE6
names: Similarity
messages: Belongs to the cytochrome P450 family.

219594:LOC116501356
gene id: 219594:LOC116501356
uniprot id: A0A6J3EMZ0
names: Subcellular Location Annotation
messages: Membrane

219594:WSCD1
gene id: 219594:WSCD1
uniprot id: A0A6J3E154
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WSCD family.
messages: Golgi apparatus membrane
messages: Sialate:O-sulfotransferase which catalyzes 8-O-sulfation at the Sia-glycan level using 3'-phosphoadenosine 5'-phosphosulfate (PAPS) as a donor, forming 8-O-sulfated Sia (Sia8S)-glycans.

219594:MAFB
gene id: 219594:MAFB
uniprot id: A0A6J3DUX1
names: Similarity
messages: Belongs to the bZIP family. Maf subfamily.

219594:KCNK9
gene id: 219594:KCNK9
uniprot id: A0A6J3CKE7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
messages: Membrane
messages: pH-dependent, voltage-insensitive, background potassium channel protein.

219594:LOC116498227
gene id: 219594:LOC116498227
uniprot id: A0A6J3E411
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:PPP1CB
gene id: 219594:PPP1CB
uniprot id: A0A6J3CQ03
names: Similarity
messages: Belongs to the PPP phosphatase family. PP-1 subfamily.

219594:ZDHHC18
gene id: 219594:ZDHHC18
uniprot id: A0A6J3E7T4
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

219594:STOML1
gene id: 219594:STOML1
uniprot id: A0A6J3DI49
uniprot id: A0A6J3DMA0
names: Similarity
messages: Belongs to the band 7/mec-2 family.

219594:UBE2I
gene id: 219594:UBE2I
uniprot id: A0A6J3DRR3
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

219594:RHBDD1
gene id: 219594:RHBDD1
uniprot id: A0A6J3DJE5
names: Subcellular Location Annotation
messages: Membrane

219594:GABRG3
gene id: 219594:GABRG3
uniprot id: A0A6J3E658
uniprot id: A0A6J3E6X5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

219594:CAV2
gene id: 219594:CAV2
uniprot id: A0A6J3ED70
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the caveolin family.
messages: Cell membrane
messages: Golgi apparatus membrane
messages: May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity.
messages: Membrane
messages: caveola

219594:POMGNT2
gene id: 219594:POMGNT2
uniprot id: A0A6J3CF58
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 61 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

219594:PGAP3
gene id: 219594:PGAP3
uniprot id: A0A6J3E4S4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PGAP3 family.
messages: Golgi apparatus membrane
messages: Involved in the lipid remodeling steps of GPI-anchor maturation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

219594:ADK
gene id: 219594:ADK
uniprot id: A0A6J3D5X5
uniprot id: A0A6J3DBT0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP dependent phosphorylation of adenosine and other related nucleoside analogs to monophosphate derivatives.
messages: Belongs to the carbohydrate kinase PfkB family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Monomer.
messages: Nucleus

219594:YRDC
gene id: 219594:YRDC
uniprot id: A0A6J3E5F6
names: Similarity
messages: Belongs to the SUA5 family.

219594:NEFL
gene id: 219594:NEFL
uniprot id: A0A6J3E8C1
names: Similarity
messages: Belongs to the intermediate filament family.

219594:CDH19
gene id: 219594:CDH19
uniprot id: A0A6J3CFZ2
names: Function
names: Subcellular Location Annotation
messages: Cadherins are calcium-dependent cell adhesion proteins.
messages: Cell membrane

219594:STRADA
gene id: 219594:STRADA
uniprot id: A0A6J3E4F7
uniprot id: A0A6J3E8S4
uniprot id: A0A6J3E9F0
uniprot id: A0A6J3EAV1
names: Function
names: Similarity
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.
messages: Pseudokinase which, in complex with CAB39/MO25 (CAB39/MO25alpha or CAB39L/MO25beta), binds to and activates STK11/LKB1. Adopts a closed conformation typical of active protein kinases and binds STK11/LKB1 as a pseudosubstrate, promoting conformational change of STK11/LKB1 in an active conformation.

219594:ACTR10
gene id: 219594:ACTR10
uniprot id: A0A6J3D1R1
names: Similarity
messages: Belongs to the actin family.

219594:HAAO
gene id: 219594:HAAO
uniprot id: A0A6J3CR18
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 3-HAO family.
messages: Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

219594:RPS21
gene id: 219594:RPS21
uniprot id: A0A6J3DU22
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eS21 family.
messages: Component of the 40S small ribosomal subunit.
messages: Endoplasmic reticulum
messages: Rough endoplasmic reticulum
messages: cytosol

219594:LOC116490305
gene id: 219594:LOC116490305
uniprot id: A0A6J3D4J9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 2 family.
messages: Golgi apparatus membrane
messages: Membrane

219594:NDUFB8
gene id: 219594:NDUFB8
uniprot id: A0A6J3DAC0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFB8 subunit family.
messages: Complex I is composed of 45 different subunits.
messages: Mitochondrion inner membrane

219594:HEATR5A
gene id: 219594:HEATR5A
uniprot id: A0A6J3D1L8
uniprot id: A0A6J3D1M3
uniprot id: A0A6J3D400
uniprot id: A0A6J3D4C9
uniprot id: A0A6J3D6J7
uniprot id: A0A6J3D7E9
names: Similarity
messages: Belongs to the HEATR5 family.

219594:AMPD2
gene id: 219594:AMPD2
uniprot id: A0A6J3E865
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.

219594:FXYD2
gene id: 219594:FXYD2
uniprot id: A0A6J3E704
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FXYD family.
messages: May be involved in forming the receptor site for cardiac glycoside binding or may modulate the transport function of the sodium ATPase.
messages: Membrane
messages: Regulatory subunit of the sodium/potassium-transporting ATPase which is composed of a catalytic alpha subunit, an auxiliary non-catalytic beta subunit and an additional regulatory subunit.

219594:LOC116485368
gene id: 219594:LOC116485368
uniprot id: A0A6J3CC37
names: Similarity
messages: Belongs to the serpin family. Ov-serpin subfamily.

219594:VSTM5
gene id: 219594:VSTM5
uniprot id: A0A6J3DJ19
names: Subcellular Location Annotation
messages: Membrane

219594:LCA5
gene id: 219594:LCA5
uniprot id: A0A6J3CSD3
names: Similarity
messages: Belongs to the LCA5 family.

219594:LOC116495540
gene id: 219594:LOC116495540
uniprot id: A0A6J3DVK2
names: Subcellular Location Annotation
messages: Nucleus

219594:LOC116489514
gene id: 219594:LOC116489514
uniprot id: A0A6J3D058
names: Similarity
messages: Belongs to the peptidase A1 family.

219594:KIF1B
gene id: 219594:KIF1B
uniprot id: A0A6J3E1K9
uniprot id: A0A6J3E1L3
uniprot id: A0A6J3E2X6
uniprot id: A0A6J3E2Y0
uniprot id: A0A6J3E2Y4
uniprot id: A0A6J3E5V4
uniprot id: A0A6J3E6L4
uniprot id: A0A6J3E6L9
uniprot id: A0A6J3E7U6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.
messages: axon

219594:GRB7
gene id: 219594:GRB7
uniprot id: A0A6J3EA06
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GRB7/10/14 family.
messages: Cytoplasm

219594:GINS2
gene id: 219594:GINS2
uniprot id: A0A6J3DJ82
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GINS2/PSF2 family.
messages: Chromosome
messages: Component of the GINS complex.
messages: Nucleus

219594:MAPK9
gene id: 219594:MAPK9
uniprot id: A0A6J3DNP2
uniprot id: A0A6J3DQZ5
uniprot id: A0A6J3DT01
uniprot id: A0A6J3DTV9
uniprot id: A0A6J3DTW2
uniprot id: A0A6J3DUR3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MAP kinase subfamily.
messages: Cytoplasm
messages: Responds to activation by environmental stress and pro-inflammatory cytokines by phosphorylating a number of transcription factors, and thus regulates transcriptional activity.

219594:TXNL4B
gene id: 219594:TXNL4B
uniprot id: A0A6J3DKM2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DIM1 family.
messages: Nucleus
messages: Plays role in pre-mRNA splicing.

219594:PSMA2
gene id: 219594:PSMA2
uniprot id: A0A6J3CIL6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1A family.
messages: Cytoplasm
messages: Nucleus
messages: The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits.

219594:PITX2
gene id: 219594:PITX2
uniprot id: A0A6J3D1P7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the paired homeobox family. Bicoid subfamily.
messages: Nucleus

219594:YEATS2
gene id: 219594:YEATS2
uniprot id: A0A6J3DBH1
uniprot id: A0A6J3DF89
uniprot id: A0A6J3DH05
uniprot id: A0A6J3DHH7
names: Subcellular Location Annotation
messages: Nucleus

219594:ABL2
gene id: 219594:ABL2
uniprot id: A0A6J3DFK1
names: Similarity
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.

219594:REEP1
gene id: 219594:REEP1
uniprot id: A0A6J3CSD9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DP1 family.
messages: Membrane

219594:SF3B1
gene id: 219594:SF3B1
uniprot id: A0A6J3D5B8
uniprot id: A0A6J3D5N0
uniprot id: A0A6J3D7W2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SF3B1 family.
messages: Nucleus

219594:LOC116500943
gene id: 219594:LOC116500943
uniprot id: A0A6J3EEP5
uniprot id: A0A6J3EG45
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the organo anion transporter (TC 2.A.60) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Secreted

219594:HDHD2
gene id: 219594:HDHD2
uniprot id: A0A6J3ECX5
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.

219594:ADSS2
gene id: 219594:ADSS2
uniprot id: A0A6J3CNV2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Mitochondrion
messages: Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP.
messages: Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis.

219594:HSPB7
gene id: 219594:HSPB7
uniprot id: A0A6J3E5W2
uniprot id: A0A6J3E6M6
uniprot id: A0A6J3E7V6
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

219594:TRPM6
gene id: 219594:TRPM6
uniprot id: A0A6J3EHY7
names: Similarity
names: Subcellular Location Annotation
messages: In the C-terminal section; belongs to the protein kinase superfamily. Alpha-type protein kinase family. ALPK subfamily.
messages: Membrane

219594:ATP6V1B1
gene id: 219594:ATP6V1B1
uniprot id: A0A6J3CZS9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Apical cell membrane
messages: Belongs to the ATPase alpha/beta chains family.
messages: Non-catalytic subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment.
messages: V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex. The V1 complex consists of three catalytic AB heterodimers that form a heterohexamer, three peripheral stalks each consisting of EG heterodimers, one central rotor including subunits D and F, and the regulatory subunits C and H. The proton translocation complex V0 consists of the proton transport subunit a, a ring of proteolipid subunits c9c'', rotary subunit d, subunits e and f, and the accessory subunits.

219594:HTR1B
gene id: 219594:HTR1B
uniprot id: A0A6J3CNT8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Homodimer. Heterodimer with HTR1D.
messages: Membrane

219594:TULP1
gene id: 219594:TULP1
uniprot id: A0A6J3EB27
names: Similarity
messages: Belongs to the TUB family.

219594:C8A
gene id: 219594:C8A
uniprot id: A0A6J3DDK7
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complement C6/C7/C8/C9 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Secreted

219594:LOC116491131
gene id: 219594:LOC116491131
uniprot id: A0A6J3D919
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prominin family.
messages: Membrane
messages: microvillus membrane

219594:THEMIS
gene id: 219594:THEMIS
uniprot id: A0A6J3CQE4
names: Similarity
messages: Belongs to the themis family.

219594:SCGN
gene id: 219594:SCGN
uniprot id: A0A6J3CHW3
names: Subcellular Location Annotation
messages: Cytoplasm

219594:GRIK4
gene id: 219594:GRIK4
uniprot id: A0A6J3E3R0
uniprot id: A0A6J3E6L5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Receptor for glutamate that functions as a ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system.

219594:RAB39A
gene id: 219594:RAB39A
uniprot id: A0A6J3DU95
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Cell membrane
messages: Membrane

219594:LOC116493083
gene id: 219594:LOC116493083
uniprot id: A0A6J3DF56
names: Function
names: Similarity
names: Subunit
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. Pelle subfamily.
messages: Binds to the IL-1 type I receptor following IL-1 engagement, triggering intracellular signaling cascades leading to transcriptional up-regulation and mRNA stabilization.
messages: Interacts with MYD88. IL-1 stimulation leads to the formation of a signaling complex which dissociates from the IL-1 receptor following the binding of PELI1.

219594:SEMA3E
gene id: 219594:SEMA3E
uniprot id: A0A6J3DUF0
names: Caution
names: Similarity
messages: Belongs to the semaphorin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:DDRGK1
gene id: 219594:DDRGK1
uniprot id: A0A6J3CU41
names: Similarity
messages: Belongs to the DDRGK1 family.

219594:MAP4K3
gene id: 219594:MAP4K3
uniprot id: A0A6J3CMQ2
uniprot id: A0A6J3CNT3
uniprot id: A0A6J3CS24
names: Function
names: Similarity
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.
messages: May play a role in the response to environmental stress. Appears to act upstream of the JUN N-terminal pathway.

219594:SNU13
gene id: 219594:SNU13
uniprot id: A0A6J3EHU9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic ribosomal protein eL8 family.
messages: Common component of the spliceosome and rRNA processing machinery.
messages: nucleolus

219594:LOC116497934
gene id: 219594:LOC116497934
uniprot id: A0A6J3E941
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM45 family.
messages: Membrane

219594:LOC116498805
gene id: 219594:LOC116498805
uniprot id: A0A6J3ECR4
names: Subcellular Location Annotation
messages: Membrane

219594:LOC116495777
gene id: 219594:LOC116495777
uniprot id: A0A6J3DSH2
names: Similarity
messages: Belongs to the glycosyl hydrolase 47 family.

219594:ATP6
gene id: 219594:ATP6
uniprot id: A0A068LAT8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase A chain family.
messages: Membrane
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Key component of the proton channel; it may play a direct role in the translocation of protons across the membrane.
messages: Mitochondrion inner membrane

219594:DMTN
gene id: 219594:DMTN
uniprot id: A0A6J3EDT9
names: Subcellular Location Annotation
messages: Cytoplasm

219594:LOC116500117
gene id: 219594:LOC116500117
uniprot id: A0A6J3ECI1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

219594:PFKFB2
gene id: 219594:PFKFB2
uniprot id: A0A6J3E6E1
uniprot id: A0A6J3EAW6
uniprot id: A0A6J3EBG6
names: Similarity
messages: In the C-terminal section; belongs to the phosphoglycerate mutase family.

219594:RPL37
gene id: 219594:RPL37
uniprot id: A0A6J3EHF7
names: Function
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL37 family.
messages: Component of the large ribosomal subunit. The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.

219594:SQSTM1
gene id: 219594:SQSTM1
uniprot id: A0A6J3DTT8
uniprot id: A0A6J3DUP5
names: Subcellular Location Annotation
messages: autophagosome

219594:GGT7
gene id: 219594:GGT7
uniprot id: A0A6J3DSG5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyltransferase family.
messages: Cleaves the gamma-glutamyl peptide bond of glutathione and glutathione conjugates.
messages: Membrane

219594:RNF34
gene id: 219594:RNF34
uniprot id: A0A6J3DWJ8
names: Subcellular Location Annotation
messages: Cell membrane

219594:FRMPD2
gene id: 219594:FRMPD2
uniprot id: A0A6J3DA02
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class subfamily.
messages: cytoskeleton

219594:LOC116498334
gene id: 219594:LOC116498334
uniprot id: A0A6J3E995
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the somatotropin/prolactin family.
messages: Secreted

219594:ALB
gene id: 219594:ALB
uniprot id: A0A6J3D0U0
names: Subcellular Location Annotation
messages: Secreted

219594:ACVR2A
gene id: 219594:ACVR2A
uniprot id: A0A6J3D6Y4
uniprot id: A0A6J3D9N4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
messages: Membrane

219594:ABLIM3
gene id: 219594:ABLIM3
uniprot id: A0A6J3DNB6
uniprot id: A0A6J3DNC2
uniprot id: A0A6J3DNC6
uniprot id: A0A6J3DQN0
uniprot id: A0A6J3DQN5
uniprot id: A0A6J3DQP0
uniprot id: A0A6J3DSP4
uniprot id: A0A6J3DSP8
uniprot id: A0A6J3DSQ3
uniprot id: A0A6J3DTH6
uniprot id: A0A6J3DTI1
uniprot id: A0A6J3DTI6
uniprot id: A0A6J3DUE1
uniprot id: A0A6J3DUE4
names: Subcellular Location Annotation
messages: Cytoplasm

219594:MED30
gene id: 219594:MED30
uniprot id: A0A6J3CP08
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Mediator complex subunit 30 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Nucleus

219594:C3
gene id: 219594:C3
uniprot id: A0A6J3EG57
names: Subcellular Location Annotation
messages: Secreted

219594:AR
gene id: 219594:AR
uniprot id: A0A6J3DQZ6
uniprot id: A0A6J3DRT0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR3 subfamily.
messages: Nucleus

219594:NDP
gene id: 219594:NDP
uniprot id: A0A6J3CP43
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

219594:GPRC5C
gene id: 219594:GPRC5C
uniprot id: A0A6J3E0Y9
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

219594:GPATCH1
gene id: 219594:GPATCH1
uniprot id: A0A6J3DPV0
names: Similarity
messages: Belongs to the GPATCH1 family.

219594:LOC116501406
gene id: 219594:LOC116501406
uniprot id: A0A6J3EN57
names: Similarity
messages: Belongs to the UPF0729 family.

219594:LOC116486359
gene id: 219594:LOC116486359
uniprot id: A0A6J3CK49
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily.

219594:C1R
gene id: 219594:C1R
uniprot id: A0A6J3EQY3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:RNFT1
gene id: 219594:RNFT1
uniprot id: A0A6J3DYW1
uniprot id: A0A6J3E356
names: Subcellular Location Annotation
messages: Membrane

219594:USP24
gene id: 219594:USP24
uniprot id: A0A6J3DEV5
names: Similarity
messages: Belongs to the peptidase C19 family.

219594:PPP1R12A
gene id: 219594:PPP1R12A
uniprot id: A0A6J3E074
uniprot id: A0A6J3E4E9
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: PP1 comprises a catalytic subunit, and one or several targeting or regulatory subunits.

219594:GTF2E1
gene id: 219594:GTF2E1
uniprot id: A0A6J3EPN0
names: Function
names: Similarity
messages: Belongs to the TFIIE alpha subunit family.
messages: Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase.

219594:SLC39A10
gene id: 219594:SLC39A10
uniprot id: A0A6J3D2B9
uniprot id: A0A6J3D7D3
uniprot id: A0A6J3D875
names: Subcellular Location Annotation
messages: Membrane

219594:TMEM14A
gene id: 219594:TMEM14A
uniprot id: A0A6J3CQE8
names: Similarity
messages: Belongs to the TMEM14 family.

219594:PRDM4
gene id: 219594:PRDM4
uniprot id: A0A6J3D8P9
names: Function
names: Subcellular Location Annotation
messages: May function as a transcription factor involved in cell differentiation.
messages: Nucleus

219594:AASDHPPT
gene id: 219594:AASDHPPT
uniprot id: A0A6J3DMJ0
names: Similarity
messages: Belongs to the P-Pant transferase superfamily. AcpS family.

219594:LOC116497549
gene id: 219594:LOC116497549
uniprot id: A0A6J3E5Y9
names: Similarity
messages: Belongs to the 'GDXG' lipolytic enzyme family.

219594:CBLB
gene id: 219594:CBLB
uniprot id: A0A6J3EFY6
names: Domain
names: Function
messages: E3 ubiquitin-protein ligase which accepts ubiquitin from specific E2 ubiquitin-conjugating enzymes, and transfers it to substrates, generally promoting their degradation by the proteasome.
messages: The N-terminus is composed of the phosphotyrosine binding (PTB) domain, a short linker region and the RING-type zinc finger. The PTB domain, which is also called TKB (tyrosine kinase binding) domain, is composed of three different subdomains: a four-helix bundle (4H), a calcium-binding EF hand and a divergent SH2 domain.

219594:DMD
gene id: 219594:DMD
uniprot id: A0A6J3DBY7
uniprot id: A0A6J3DC38
uniprot id: A0A6J3DC48
uniprot id: A0A6J3DEM5
uniprot id: A0A6J3DFS9
uniprot id: A0A6J3DFW3
uniprot id: A0A6J3DFZ3
uniprot id: A0A6J3DHJ5
uniprot id: A0A6J3DI36
names: Function
names: Subcellular Location Annotation
messages: May play a role in anchoring the cytoskeleton to the plasma membrane.
messages: cytoskeleton

219594:ADCY8
gene id: 219594:ADCY8
uniprot id: A0A6J3CJX1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
messages: Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.
messages: Membrane

219594:NOS3
gene id: 219594:NOS3
uniprot id: A0A6J3CMH6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NOS family.
messages: Binds 1 FAD.
messages: Binds 1 FMN.
messages: Produces nitric oxide (NO) which is a messenger molecule with diverse functions throughout the body.

219594:ELP1
gene id: 219594:ELP1
uniprot id: A0A6J3EIX6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELP1/IKA1 family.
messages: Component of the elongator complex which is required for multiple tRNA modifications, including mcm5U (5-methoxycarbonylmethyl uridine), mcm5s2U (5-methoxycarbonylmethyl-2-thiouridine), and ncm5U (5-carbamoylmethyl uridine). The elongator complex catalyzes formation of carboxymethyluridine in the wobble base at position 34 in tRNAs.
messages: Cytoplasm
messages: Nucleus

219594:MYADML2
gene id: 219594:MYADML2
uniprot id: A0A6J3DXB2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MAL family.
messages: Membrane

219594:CCND1
gene id: 219594:CCND1
uniprot id: A0A6J3D1F9
uniprot id: A0A6J3D6E3
names: Similarity
messages: Belongs to the cyclin family.

219594:PCK1
gene id: 219594:PCK1
uniprot id: A0A6J3DXW8
names: Similarity
messages: Belongs to the phosphoenolpyruvate carboxykinase [GTP] family.

219594:RAB14
gene id: 219594:RAB14
uniprot id: A0A6J3E1K0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Early endosome membrane
messages: Endosome membrane
messages: Golgi apparatus membrane
messages: Recycling endosome
messages: phagosome
messages: trans-Golgi network membrane

219594:PRKAR1A
gene id: 219594:PRKAR1A
uniprot id: A0A6J3E1Z0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cAMP-dependent kinase regulatory chain family.
messages: Cell membrane
messages: Membrane

219594:TGFBI
gene id: 219594:TGFBI
uniprot id: A0A6J3DQA1
names: Subcellular Location Annotation
messages: extracellular matrix

219594:NUP155
gene id: 219594:NUP155
uniprot id: A0A6J3EFZ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the non-repetitive/WGA-negative nucleoporin family.
messages: nuclear pore complex

219594:ACP1
gene id: 219594:ACP1
uniprot id: A0A6J3CMR0
uniprot id: A0A6J3CTS9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acts on tyrosine phosphorylated proteins, low-MW aryl phosphates and natural and synthetic acyl phosphates.
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.
messages: Cytoplasm

219594:BMP5
gene id: 219594:BMP5
uniprot id: A0A6J3CLQ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TGF-beta family.
messages: Secreted

219594:PTPRN
gene id: 219594:PTPRN
uniprot id: A0A6J3DAS9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Receptor class 8 subfamily.
messages: Membrane
messages: secretory vesicle membrane

219594:NKX3-1
gene id: 219594:NKX3-1
uniprot id: A0A6J3EFN5
names: Subcellular Location Annotation
messages: Nucleus

219594:ACTG1
gene id: 219594:ACTG1
uniprot id: A0A6J3DXC7
names: Similarity
messages: Belongs to the actin family.

219594:DGCR2
gene id: 219594:DGCR2
uniprot id: A0A6J3DYN1
uniprot id: A0A6J3DZQ8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:SEC22B
gene id: 219594:SEC22B
uniprot id: A0A6J3DE24
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptobrevin family.
messages: Endoplasmic reticulum membrane
messages: Endoplasmic reticulum-Golgi intermediate compartment membrane
messages: Melanosome
messages: Membrane
messages: SNARE involved in targeting and fusion of ER-derived transport vesicles with the Golgi complex as well as Golgi-derived retrograde transport vesicles with the ER.
messages: cis-Golgi network membrane
messages: trans-Golgi network membrane

219594:GJC1
gene id: 219594:GJC1
uniprot id: A0A6J3E697
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family. Gamma-type subfamily.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

219594:NDUFAF7
gene id: 219594:NDUFAF7
uniprot id: A0A6J3CRZ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Arginine methyltransferase involved in the assembly or stability of mitochondrial NADH:ubiquinone oxidoreductase complex (complex I).
messages: Belongs to the NDUFAF7 family.
messages: Mitochondrion

219594:RWDD3
gene id: 219594:RWDD3
uniprot id: A0A6J3DDW7
uniprot id: A0A6J3DH91
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

219594:LAMA2
gene id: 219594:LAMA2
uniprot id: A0A6J3CS01
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: basement membrane

219594:LOC116502285
gene id: 219594:LOC116502285
uniprot id: A0A6J3EQ56
names: Similarity
messages: Belongs to the interleukin-1 receptor family.

219594:KIAA1191
gene id: 219594:KIAA1191
uniprot id: A0A6J3DSK7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P33MONOX family.
messages: Cytoplasm

219594:POU3F1
gene id: 219594:POU3F1
uniprot id: A0A6J3E885
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the POU transcription factor family. Class-3 subfamily.
messages: Nucleus

219594:UBE2E3
gene id: 219594:UBE2E3
uniprot id: A0A6J3D9V2
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

219594:GAA
gene id: 219594:GAA
uniprot id: A0A6J3E0Z9
names: Caution
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:SHTN1
gene id: 219594:SHTN1
uniprot id: A0A6J3D8L7
uniprot id: A0A6J3DBB1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the shootin family.
messages: Perikaryon
messages: axon
messages: cytoskeleton
messages: filopodium
messages: lamellipodium

219594:LOC116501413
gene id: 219594:LOC116501413
uniprot id: A0A6J3EI10
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

219594:LOC116486531
gene id: 219594:LOC116486531
uniprot id: A0A6J3CJT0
uniprot id: A0A6J3CMX4
uniprot id: A0A6J3CPE1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium channel (TC 1.A.1.10) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient.
messages: Membrane

219594:NPVF
gene id: 219594:NPVF
uniprot id: A0A6J3CC19
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FARP (FMRFamide related peptide) family.
messages: Secreted

219594:ATP6V1A
gene id: 219594:ATP6V1A
uniprot id: A0A6J3CT81
names: Similarity
messages: Belongs to the ATPase alpha/beta chains family.

219594:C1H11orf87
gene id: 219594:C1H11orf87
uniprot id: A0A6J3EK03
names: Subcellular Location Annotation
messages: Membrane

219594:DYDC1
gene id: 219594:DYDC1
uniprot id: A0A6J3DA35
names: Similarity
messages: Belongs to the dpy-30 family.

219594:SLC15A4
gene id: 219594:SLC15A4
uniprot id: A0A6J3DUB8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.
messages: Membrane

219594:GAB3
gene id: 219594:GAB3
uniprot id: A0A6J3DNB7
uniprot id: A0A6J3DS72
names: Similarity
messages: Belongs to the GAB family.

219594:C21H1orf174
gene id: 219594:C21H1orf174
uniprot id: A0A6J3E6P7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0688 family.
messages: Nucleus

219594:SLC7A13
gene id: 219594:SLC7A13
uniprot id: A0A6J3CC93
names: Subcellular Location Annotation
messages: Membrane

219594:ABCG5
gene id: 219594:ABCG5
uniprot id: A0A6J3CT16
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCG family. Eye pigment precursor importer (TC 3.A.1.204) subfamily.
messages: Membrane

219594:HOXB3
gene id: 219594:HOXB3
uniprot id: A0A6J3E9E6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Antp homeobox family.
messages: Nucleus

219594:LOC116502198
gene id: 219594:LOC116502198
uniprot id: A0A6J3EKQ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

219594:MFSD11
gene id: 219594:MFSD11
uniprot id: A0A6J3DVX1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the unc-93 family.
messages: Membrane

219594:RBBP5
gene id: 219594:RBBP5
uniprot id: A0A6J3E633
uniprot id: A0A6J3EAK7
uniprot id: A0A6J3EB68
uniprot id: A0A6J3ECS2
names: Subcellular Location Annotation
messages: Nucleus

219594:GDNF
gene id: 219594:GDNF
uniprot id: A0A6J3EGV0
uniprot id: A0A6J3EM40
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TGF-beta family. GDNF subfamily.
messages: Secreted

219594:MANBA
gene id: 219594:MANBA
uniprot id: A0A6J3CX32
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycosyl hydrolase 2 family.
messages: Exoglycosidase that cleaves the single beta-linked mannose residue from the non-reducing end of all N-linked glycoprotein oligosaccharides.
messages: Lysosome
messages: Monomer.

219594:PIK3R2
gene id: 219594:PIK3R2
uniprot id: A0A6J3EE51
names: Similarity
messages: Belongs to the PI3K p85 subunit family.

219594:SLC23A3
gene id: 219594:SLC23A3
uniprot id: A0A6J3D9H4
names: Subcellular Location Annotation
messages: Membrane

219594:LOC116495866
gene id: 219594:LOC116495866
uniprot id: A0A6J3DSS8
names: Cofactor
names: Similarity
messages: Belongs to the transglutaminase superfamily. Transglutaminase family.
messages: Binds 1 Ca(2+) ion per subunit.

219594:BTBD10
gene id: 219594:BTBD10
uniprot id: A0A6J3CWZ6
uniprot id: A0A6J3CZ88
uniprot id: A0A6J3D2X7
names: Subcellular Location Annotation
messages: Cytoplasm

219594:LOC116501349
gene id: 219594:LOC116501349
uniprot id: A0A6J3ELH6
names: Subcellular Location Annotation
messages: Membrane

219594:TOM1L2
gene id: 219594:TOM1L2
uniprot id: A0A6J3DR60
uniprot id: A0A6J3DTD8
uniprot id: A0A6J3DVI3
names: Similarity
messages: Belongs to the TOM1 family.

219594:LOC116498543
gene id: 219594:LOC116498543
uniprot id: A0A6J3EBJ6
names: Similarity
names: Subunit
messages: Belongs to the avian keratin family.
messages: The avian keratins (F-ker, S-ker, C-ker and B-ker) are a complex mixture of very similar polypeptides.

219594:MTHFD1L
gene id: 219594:MTHFD1L
uniprot id: A0A6J3CPM0
names: Similarity
names: Subunit
messages: Homodimer.
messages: In the C-terminal section; belongs to the formate--tetrahydrofolate ligase family.
messages: In the N-terminal section; belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.

219594:PPARG
gene id: 219594:PPARG
uniprot id: A0A6J3DEV2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the nuclear hormone receptor family. NR1 subfamily.
messages: Cytoplasm
messages: Heterodimer with other nuclear receptors.
messages: Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. May play a role in the regulation of circadian rhythm.
messages: Nucleus

219594:KIF4A
gene id: 219594:KIF4A
uniprot id: A0A6J3DPA3
uniprot id: A0A6J3DRB5
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

219594:LOC116494698
gene id: 219594:LOC116494698
uniprot id: A0A6J3DSF2
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

219594:LOC116499704
gene id: 219594:LOC116499704
uniprot id: A0A6J3EGG5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the selenium-binding protein family.
messages: Catalyzes the oxidation of methanethiol, an organosulfur compound known to be produced in substantial amounts by gut bacteria. Selenium-binding protein which may be involved in the sensing of reactive xenobiotics in the cytoplasm. May be involved in intra-Golgi protein transport.
messages: Membrane
messages: Nucleus
messages: cytosol

219594:CAPZA1
gene id: 219594:CAPZA1
uniprot id: A0A6J3EAF2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the F-actin-capping protein alpha subunit family.
messages: F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.
messages: Heterodimer of an alpha and a beta subunit.

219594:ZNF503
gene id: 219594:ZNF503
uniprot id: A0A6J3D9T8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Elbow/Noc family.
messages: Nucleus

219594:LOC116489414
gene id: 219594:LOC116489414
uniprot id: A0A6J3CX81
names: Similarity
messages: Belongs to the CD225/Dispanin family.

219594:CPSF4
gene id: 219594:CPSF4
uniprot id: A0A6J3DVG8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CPSF4/YTH1 family.
messages: Component of the cleavage and polyadenylation specificity factor (CPSF) complex that play a key role in pre-mRNA 3'-end formation, recognizing the AAUAAA signal sequence and interacting with poly(A) polymerase and other factors to bring about cleavage and poly(A) addition. CPSF4 binds RNA polymers with a preference for poly(U).
messages: Component of the cleavage and polyadenylation specificity factor (CPSF) complex.
messages: Nucleus

219594:LOC116499575
gene id: 219594:LOC116499575
uniprot id: A0A6J3EE83
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pentraxin family.
messages: Binds 2 calcium ions per subunit.
messages: Homopentamer. Pentaxin (or pentraxin) have a discoid arrangement of 5 non-covalently bound subunits.
messages: Secreted

219594:LOC116497746
gene id: 219594:LOC116497746
uniprot id: A0A6J3E6U1
names: Similarity
messages: Belongs to the 'GDXG' lipolytic enzyme family.

219594:LOC116497430
gene id: 219594:LOC116497430
uniprot id: A0A6J3E1S6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family.
messages: Membrane

219594:NADK
gene id: 219594:NADK
uniprot id: A0A6J3E790
names: Similarity
messages: Belongs to the NAD kinase family.

219594:PSMA4
gene id: 219594:PSMA4
uniprot id: A0A6J3DG95
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1A family.
messages: Component of the 20S core proteasome complex involved in the proteolytic degradation of most intracellular proteins. This complex plays numerous essential roles within the cell by associating with different regulatory particles. Associated with two 19S regulatory particles, forms the 26S proteasome and thus participates in the ATP-dependent degradation of ubiquitinated proteins. The 26S proteasome plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins that could impair cellular functions, and by removing proteins whose functions are no longer required. Associated with the PA200 or PA28, the 20S proteasome mediates ubiquitin-independent protein degradation. This type of proteolysis is required in several pathways including spermatogenesis (20S-PA200 complex) or generation of a subset of MHC class I-presented antigenic peptides (20S-PA28 complex).
messages: Cytoplasm
messages: Nucleus
messages: The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits.

219594:CHCHD6
gene id: 219594:CHCHD6
uniprot id: A0A6J3DLI0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MICOS complex subunit Mic19 family. Metazoan Mic25 subfamily.
messages: Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane.
messages: Membrane
messages: Mitochondrion inner membrane

219594:LRRC8D
gene id: 219594:LRRC8D
uniprot id: A0A6J3D984
uniprot id: A0A6J3DF37
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LRRC8 family.
messages: Cell membrane
messages: Membrane

219594:PEBP4
gene id: 219594:PEBP4
uniprot id: A0A6J3ECS0
names: Similarity
messages: Belongs to the phosphatidylethanolamine-binding protein family.

219594:TEAD4
gene id: 219594:TEAD4
uniprot id: A0A6J3D6C7
names: Subcellular Location Annotation
messages: Nucleus

219594:CDK5R2
gene id: 219594:CDK5R2
uniprot id: A0A6J3D6X6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cyclin-dependent kinase 5 activator family.
messages: Cell membrane
messages: Heterodimer of a catalytic subunit and a regulatory subunit.
messages: Membrane

219594:MYRFL
gene id: 219594:MYRFL
uniprot id: A0A6J3EPM6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MRF family.
messages: Membrane

219594:POLR3C
gene id: 219594:POLR3C
uniprot id: A0A6J3EBF3
uniprot id: A0A6J3EER5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic RPC3/POLR3C RNA polymerase subunit family.
messages: Component of the RNA polymerase III (Pol III) complex consisting of 17 subunits.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific core component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs.
messages: Nucleus

219594:LOC116500893
gene id: 219594:LOC116500893
uniprot id: A0A6J3EJG9
names: Similarity
messages: Belongs to the FBPase class 1 family.

219594:OPN4
gene id: 219594:OPN4
uniprot id: A0A6J3DCS7
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Opsin subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

219594:TPO
gene id: 219594:TPO
uniprot id: A0A6J3CRX0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the prostaglandin G/H synthase family.
messages: Interacts with DUOX1, DUOX2 and CYBA.
messages: Iodination and coupling of the hormonogenic tyrosines in thyroglobulin to yield the thyroid hormones T(3) and T(4).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

219594:TFEB
gene id: 219594:TFEB
uniprot id: A0A6J3E867
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MiT/TFE family.
messages: Nucleus

219594:ANXA4
gene id: 219594:ANXA4
uniprot id: A0A6J3EDB7
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: A pair of annexin repeats may form one binding site for calcium and phospholipid.
messages: Belongs to the annexin family.
messages: Zymogen granule membrane

219594:CAMTA1
gene id: 219594:CAMTA1
uniprot id: A0A6J3E112
uniprot id: A0A6J3E2E2
uniprot id: A0A6J3E589
uniprot id: A0A6J3E614
uniprot id: A0A6J3E752
names: Similarity
names: Subunit
messages: Belongs to the CAMTA family.
messages: May interact with calmodulin.

219594:GPR155
gene id: 219594:GPR155
uniprot id: A0A6J3D2Z2
uniprot id: A0A6J3D5H2
uniprot id: A0A6J3D8T8
names: Subcellular Location Annotation
messages: Membrane

219594:HSPD1
gene id: 219594:HSPD1
uniprot id: A0A6J3D545
names: Similarity
messages: Belongs to the chaperonin (HSP60) family.

219594:RAMP2
gene id: 219594:RAMP2
uniprot id: A0A6J3E9G0
names: Similarity
messages: Belongs to the RAMP family.

219594:FSCN1
gene id: 219594:FSCN1
uniprot id: A0A6J3DW80
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fascin family.
messages: cytoskeleton

219594:RSAD2
gene id: 219594:RSAD2
uniprot id: A0A6J3CTC2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RSAD2 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

219594:DUSP6
gene id: 219594:DUSP6
uniprot id: A0A6J3EQD2
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.

219594:STK3
gene id: 219594:STK3
uniprot id: A0A6J3CIT2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.
messages: Nucleus

219594:BACE1
gene id: 219594:BACE1
uniprot id: A0A6J3E3I6
uniprot id: A0A6J3E8E6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A1 family.
messages: Endosome
messages: Membrane
messages: Membrane raft
messages: Recycling endosome
messages: trans-Golgi network

219594:DCLRE1C
gene id: 219594:DCLRE1C
uniprot id: A0A6J3EKS3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA repair metallo-beta-lactamase (DRMBL) family.
messages: Nucleus

219594:FZD6
gene id: 219594:FZD6
uniprot id: A0A6J3CHS0
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor Fz/Smo family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

219594:COMTD1
gene id: 219594:COMTD1
uniprot id: A0A6J3DE47
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-dependent O-methyltransferase family.

219594:SLC29A1
gene id: 219594:SLC29A1
uniprot id: A0A6J3CSZ6
names: Similarity
names: Subcellular Location Annotation
messages: Basolateral cell membrane
messages: Belongs to the SLC29A/ENT transporter (TC 2.A.57) family.
messages: Lateral cell membrane
messages: Membrane

219594:LOC116486144
gene id: 219594:LOC116486144
uniprot id: A0A6J3CMI3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAA ATPase family.
messages: Endosome membrane
messages: Late endosome membrane
messages: Membrane

219594:GPR39
gene id: 219594:GPR39
uniprot id: A0A6J3D4V9
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

219594:MZT1
gene id: 219594:MZT1
uniprot id: A0A6J3DCE4
names: Function
names: Similarity
messages: Belongs to the MOZART1 family.
messages: Required for gamma-tubulin complex recruitment to the centrosome.

219594:UCKL1
gene id: 219594:UCKL1
uniprot id: A0A6J3DUQ9
names: Similarity
messages: Belongs to the uridine kinase family.

219594:LOC116501469
gene id: 219594:LOC116501469
uniprot id: A0A6J3EHT8
uniprot id: A0A6J3ENH2
names: Similarity
messages: Belongs to the SPIN/STSY family.

219594:LOC116491251
gene id: 219594:LOC116491251
uniprot id: A0A6J3DBX3
names: Similarity
messages: Belongs to the VPS10-related sortilin family. SORCS subfamily.

219594:USP37
gene id: 219594:USP37
uniprot id: A0A6J3D550
uniprot id: A0A6J3D8C2
names: Similarity
messages: Belongs to the peptidase C19 family.

219594:EREG
gene id: 219594:EREG
uniprot id: A0A6J3D1E9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:TSPO2
gene id: 219594:TSPO2
uniprot id: A0A6J3E7V1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TspO/BZRP family.
messages: Membrane

219594:TBC1D24
gene id: 219594:TBC1D24
uniprot id: A0A6J3DPY2
uniprot id: A0A6J3DV69
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasmic vesicle membrane
messages: Interacts with ARF6.
messages: Membrane
messages: Presynapse

219594:SLC6A6
gene id: 219594:SLC6A6
uniprot id: A0A6J3DFN8
uniprot id: A0A6J3DIB7
uniprot id: A0A6J3DIC2
uniprot id: A0A6J3DJM5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. SLC6A6 subfamily.
messages: Cell membrane
messages: Membrane

219594:ACTR5
gene id: 219594:ACTR5
uniprot id: A0A6J3DU31
names: Similarity
messages: Belongs to the actin family.

219594:FNTA
gene id: 219594:FNTA
uniprot id: A0A6J3EJD2
names: Similarity
messages: Belongs to the protein prenyltransferase subunit alpha family.

219594:KHDRBS3
gene id: 219594:KHDRBS3
uniprot id: A0A6J3CF95
uniprot id: A0A6J3CJT8
uniprot id: A0A6J3CLI2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KHDRBS family.
messages: Cytoplasm

219594:PRPF38B
gene id: 219594:PRPF38B
uniprot id: A0A6J3DFZ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRP38 family.
messages: May be required for pre-mRNA splicing.
messages: Nucleus

219594:MACF1
gene id: 219594:MACF1
uniprot id: A0A6J3E329
names: Subcellular Location Annotation
messages: cytoskeleton

219594:STX7
gene id: 219594:STX7
uniprot id: A0A6J3CQY7
names: Similarity
messages: Belongs to the syntaxin family.

219594:NMUR1
gene id: 219594:NMUR1
uniprot id: A0A6J3DHB4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for the neuromedin-U and neuromedin-S neuropeptides.

219594:EVA1C
gene id: 219594:EVA1C
uniprot id: A0A6J3ENY5
names: Similarity
messages: Belongs to the EVA1 family.

219594:PHACTR4
gene id: 219594:PHACTR4
uniprot id: A0A6J3E824
uniprot id: A0A6J3E8P2
uniprot id: A0A6J3EA57
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphatase and actin regulator family.
messages: Binds PPP1CA and actin.
messages: Cytoplasm
messages: Regulator of protein phosphatase 1 (PP1) required for neural tube and optic fissure closure, and enteric neural crest cell (ENCCs) migration during development. Acts as an activator of PP1. During neural tube closure, localizes to the ventral neural tube and activates PP1, leading to down-regulate cell proliferation within cranial neural tissue and the neural retina. Also acts as a regulator of migration of enteric neural crest cells (ENCCs) by activating PP1, leading to repression of the integrin signaling through the rho/rock pathway.
messages: lamellipodium

219594:PAMR1
gene id: 219594:PAMR1
uniprot id: A0A6J3D2L4
uniprot id: A0A6J3D2U5
uniprot id: A0A6J3D553
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:DOP1B
gene id: 219594:DOP1B
uniprot id: A0A6J3DT99
uniprot id: A0A6J3DTM8
uniprot id: A0A6J3DXZ4
names: Similarity
messages: Belongs to the dopey family.

219594:NR3C1
gene id: 219594:NR3C1
uniprot id: A0A6J3DN49
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR3 subfamily.
messages: Mitochondrion
messages: Nucleus
messages: centrosome
messages: spindle

219594:CIAO2B
gene id: 219594:CIAO2B
uniprot id: A0A6J3DN34
names: Similarity
messages: Belongs to the MIP18 family.

219594:TESMIN
gene id: 219594:TESMIN
uniprot id: A0A6J3D3Z4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lin-54 family.
messages: Nucleus

219594:NEMF
gene id: 219594:NEMF
uniprot id: A0A6J3D2W5
names: Similarity
messages: Belongs to the NEMF family.

219594:SLC6A7
gene id: 219594:SLC6A7
uniprot id: A0A6J3DSC3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

219594:RBPJ
gene id: 219594:RBPJ
uniprot id: A0A6J3CU07
uniprot id: A0A6J3CWA0
uniprot id: A0A6J3CZ31
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Su(H) family.
messages: Nucleus

219594:PYCR1
gene id: 219594:PYCR1
uniprot id: A0A6J3E1J3
names: Similarity
messages: Belongs to the pyrroline-5-carboxylate reductase family.

219594:EDN1
gene id: 219594:EDN1
uniprot id: A0A6J3CJH9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endothelin/sarafotoxin family.
messages: Secreted

219594:ILKAP
gene id: 219594:ILKAP
uniprot id: A0A6J3DGF9
uniprot id: A0A6J3DJD2
names: Similarity
messages: Belongs to the PP2C family.

219594:LOC116492076
gene id: 219594:LOC116492076
uniprot id: A0A6J3DG79
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:UBAC2
gene id: 219594:UBAC2
uniprot id: A0A6J3CIH1
uniprot id: A0A6J3CLG3
names: Subcellular Location Annotation
messages: Membrane

219594:NAF1
gene id: 219594:NAF1
uniprot id: A0A6J3CV23
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAF1 family.
messages: Nucleus

219594:ADCYAP1
gene id: 219594:ADCYAP1
uniprot id: A0A6J3CHE4
uniprot id: A0A6J3CIX8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glucagon family.
messages: Secreted

219594:ITGA8
gene id: 219594:ITGA8
uniprot id: A0A6J3CR40
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin alpha chain family.
messages: Membrane

219594:TASP1
gene id: 219594:TASP1
uniprot id: A0A6J3CP27
uniprot id: A0A6J3CR15
uniprot id: A0A6J3CRQ9
uniprot id: A0A6J3CU02
uniprot id: A0A6J3CV51
names: Similarity
messages: Belongs to the Ntn-hydrolase family.

219594:STIM2
gene id: 219594:STIM2
uniprot id: A0A6J3CY59
names: Subcellular Location Annotation
messages: Membrane

219594:LOC116500474
gene id: 219594:LOC116500474
uniprot id: A0A6J3ECH9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the urea transporter family.
messages: Cell membrane
messages: Membrane

219594:RRP36
gene id: 219594:RRP36
uniprot id: A0A6J3CRS5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associates with 90S and pre-40S pre-ribosomal particles.
messages: Belongs to the RRP36 family.
messages: Component of the 90S pre-ribosome involved in the maturation of rRNAs. Required for early cleavages of the pre-RNAs in the 40S ribosomal subunit maturation pathway.
messages: nucleolus

219594:MSRB1
gene id: 219594:MSRB1
uniprot id: A0A6J3DU99
names: Similarity
messages: Belongs to the MsrB Met sulfoxide reductase family.

219594:APAF1
gene id: 219594:APAF1
uniprot id: A0A6J3E0P4
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Monomer. Oligomerizes upon binding of cytochrome c and dATP.
messages: Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP.

219594:GHRH
gene id: 219594:GHRH
uniprot id: A0A6J3DTF4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glucagon family.
messages: Secreted

219594:TUBA1A
gene id: 219594:TUBA1A
uniprot id: A0A6J3EFS1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.
messages: cytoskeleton

219594:LACTB2
gene id: 219594:LACTB2
uniprot id: A0A6J3CKH7
names: Function
names: Similarity
messages: Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.
messages: Endoribonuclease; cleaves preferentially 3' to purine-pyrimidine dinucleotide motifs in single-stranded RNA. The cleavage product contains a free 3' -OH group. Has no activity with double-stranded RNA or DNA. Required for normal mitochondrial function and cell viability.

219594:PSMB4
gene id: 219594:PSMB4
uniprot id: A0A6J3EEQ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase T1B family.
messages: Cytoplasm
messages: Non-catalytic component of the proteasome.
messages: Nucleus

219594:LOC116486379
gene id: 219594:LOC116486379
uniprot id: A0A6J3CJ23
names: Similarity
messages: Belongs to the DSD1 family.

219594:LOC116500237
gene id: 219594:LOC116500237
uniprot id: A0A6J3EI45
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the immunoglobulin superfamily. BTN/MOG family.
messages: Membrane

219594:SLC26A1
gene id: 219594:SLC26A1
uniprot id: A0A6J3ED84
uniprot id: A0A6J3EK21
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Membrane
messages: Sodium-independent sulfate anion transporter. Can transport other anions including bicarbonate, thiosulfate and oxalate.

219594:LOC116498307
gene id: 219594:LOC116498307
uniprot id: A0A6J3E8K2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

219594:LSM14A
gene id: 219594:LSM14A
uniprot id: A0A6J3DIX8
uniprot id: A0A6J3DLF5
uniprot id: A0A6J3DN30
names: Similarity
messages: Belongs to the LSM14 family.

219594:ADAMTS3
gene id: 219594:ADAMTS3
uniprot id: A0A6J3CU46
uniprot id: A0A6J3D095
names: Caution
names: Cofactor
names: Subcellular Location Annotation
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

219594:GDA
gene id: 219594:GDA
uniprot id: A0A6J3EH07
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. ATZ/TRZ family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia.

219594:PLCD4
gene id: 219594:PLCD4
uniprot id: A0A6J3D4G1
uniprot id: A0A6J3D7M3
names: Cofactor
messages: Binds 3 Ca(2+) ions per subunit. Two of the Ca(2+) ions are bound to the C2 domain.

219594:FRK
gene id: 219594:FRK
uniprot id: A0A6J3CPP3
names: Similarity
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.

219594:HMGCS2
gene id: 219594:HMGCS2
uniprot id: A0A6J3DD29
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. HMG-CoA synthase family.
messages: Catalyzes the condensation of acetyl-CoA with acetoacetyl-CoA to form HMG-CoA.

219594:LOC116486729
gene id: 219594:LOC116486729
uniprot id: A0A6J3CNW7
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily.

219594:LOC116489963
gene id: 219594:LOC116489963
uniprot id: A0A6J3D512
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRPH2/ROM1 family.
messages: Membrane

219594:MAP1LC3A
gene id: 219594:MAP1LC3A
uniprot id: A0A6J3DXI1
names: Similarity
messages: Belongs to the ATG8 family.

219594:FOXL3
gene id: 219594:FOXL3
uniprot id: A0A6J3DSJ8
names: Subcellular Location Annotation
messages: Nucleus

219594:LOC116494551
gene id: 219594:LOC116494551
uniprot id: A0A6J3DSW6
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

219594:TNFRSF8
gene id: 219594:TNFRSF8
uniprot id: A0A6J3E2R5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:CAMK1G
gene id: 219594:CAMK1G
uniprot id: A0A6J3E850
names: Similarity
messages: Belongs to the protein kinase superfamily.

219594:WNK2
gene id: 219594:WNK2
uniprot id: A0A6J3DFS1
uniprot id: A0A6J3DIF2
uniprot id: A0A6J3DJQ5
uniprot id: A0A6J3DLB9
uniprot id: A0A6J3DLT3
uniprot id: A0A6J3DLT8
names: Similarity
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.

219594:LOC116492472
gene id: 219594:LOC116492472
uniprot id: A0A6J3DHW2
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:C17H12orf65
gene id: 219594:C17H12orf65
uniprot id: A0A6J3DYX9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Mitochondrion

219594:RPL26L1
gene id: 219594:RPL26L1
uniprot id: A0A6J3DNQ9
names: Similarity
messages: Belongs to the universal ribosomal protein uL24 family.

219594:PRR5L
gene id: 219594:PRR5L
uniprot id: A0A6J3D355
names: Similarity
messages: Belongs to the PROTOR family.

219594:BSN
gene id: 219594:BSN
uniprot id: A0A6J3DF66
names: Subcellular Location Annotation
messages: Presynaptic active zone

219594:XKR5
gene id: 219594:XKR5
uniprot id: A0A6J3CQK6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the XK family.
messages: Membrane

219594:CLDN16
gene id: 219594:CLDN16
uniprot id: A0A6J3DFE7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

219594:LOC116502244
gene id: 219594:LOC116502244
uniprot id: A0A6J3EJL0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPOT14 family.
messages: Cytoplasm
messages: Nucleus

219594:INTS3
gene id: 219594:INTS3
uniprot id: A0A6J3EF49
names: Similarity
messages: Belongs to the Integrator subunit 3 family.

219594:NCSTN
gene id: 219594:NCSTN
uniprot id: A0A6J3EEM2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nicastrin family.
messages: Membrane

219594:GMNN
gene id: 219594:GMNN
uniprot id: A0A6J3CFU9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the geminin family.
messages: Nucleus

219594:CNEP1R1
gene id: 219594:CNEP1R1
uniprot id: A0A6J3DMH0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CNEP1R1 family.
messages: Cytoplasm
messages: Membrane
messages: Nucleus membrane

219594:CEL
gene id: 219594:CEL
uniprot id: A0A6J3E2P1
names: Similarity
messages: Belongs to the type-B carboxylesterase/lipase family.

219594:ARF4
gene id: 219594:ARF4
uniprot id: A0A6J3DIX7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Arf family.
messages: GTP-binding protein involved in protein trafficking; modulates vesicle budding and uncoating within the Golgi apparatus.
messages: Golgi apparatus

219594:LOC116501311
gene id: 219594:LOC116501311
uniprot id: A0A6J3EG63
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

219594:SEPSECS
gene id: 219594:SEPSECS
uniprot id: A0A6J3CWH1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SepSecS family.
messages: Converts O-phosphoseryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis.
messages: Cytoplasm
messages: Homotetramer formed by a catalytic dimer and a non-catalytic dimer serving as a binding platform that orients tRNASec for catalysis. Each tetramer binds the CCA ends of two tRNAs which point to the active sites of the catalytic dimer.

219594:IST1
gene id: 219594:IST1
uniprot id: A0A6J3DMA2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IST1 family.
messages: Cytoplasmic vesicle
messages: Nucleus envelope

219594:ANKRD13A
gene id: 219594:ANKRD13A
uniprot id: A0A6J3DU51
names: Function
names: Subcellular Location Annotation
messages: Endosome
messages: Late endosome
messages: Membrane
messages: Ubiquitin-binding protein that specifically recognizes and binds 'Lys-63'-linked ubiquitin. Does not bind 'Lys-48'-linked ubiquitin. Positively regulates the internalization of ligand-activated EGFR by binding to the Ub moiety of ubiquitinated EGFR at the cell membrane.

219594:CHD9
gene id: 219594:CHD9
uniprot id: A0A6J3DK24
uniprot id: A0A6J3DMK1
uniprot id: A0A6J3DMK6
uniprot id: A0A6J3DPB1
uniprot id: A0A6J3DQJ1
uniprot id: A0A6J3DQJ6
uniprot id: A0A6J3DQK1
uniprot id: A0A6J3DR86
uniprot id: A0A6J3DR92
names: Similarity
messages: Belongs to the SNF2/RAD54 helicase family.

219594:CCT6A
gene id: 219594:CCT6A
uniprot id: A0A6J3E4X8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TCP-1 chaperonin family.
messages: Cytoplasm

219594:PTEN
gene id: 219594:PTEN
uniprot id: A0A6J3D9S9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine-phosphorylated proteins. Also acts as a lipid phosphatase, removing the phosphate in the D3 position of the inositol ring from phosphatidylinositol 3,4,5-trisphosphate, phosphatidylinositol 3,4-diphosphate, phosphatidylinositol 3-phosphate and inositol 1,3,4,5-tetrakisphosphate with order of substrate preference in vitro PtdIns(3,4,5)P3 > PtdIns(3,4)P2 > PtdIns3P > Ins(1,3,4,5)P4.
messages: Belongs to the PTEN phosphatase protein family.
messages: Cytoplasm
messages: Nucleus
messages: PML body
messages: Postsynaptic density
messages: dendritic spine

219594:INPP5B
gene id: 219594:INPP5B
uniprot id: A0A6J3E3U0
uniprot id: A0A6J3E8T0
uniprot id: A0A6J3EA96
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inositol 1,4,5-trisphosphate 5-phosphatase type II family.
messages: Early endosome membrane
messages: Endosome membrane
messages: Membrane
messages: phagosome membrane

219594:PRKCI
gene id: 219594:PRKCI
uniprot id: A0A6J3DEK5
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.

219594:MTF2
gene id: 219594:MTF2
uniprot id: A0A6J3DCZ1
names: Subcellular Location Annotation
messages: Nucleus

219594:CLNS1A
gene id: 219594:CLNS1A
uniprot id: A0A6J3EIF9
uniprot id: A0A6J3ENL2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pICln (TC 1.A.47) family.
messages: Nucleus

219594:MRPS2
gene id: 219594:MRPS2
uniprot id: A0A6J3E3S2
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

219594:LOC116494417
gene id: 219594:LOC116494417
uniprot id: A0A6J3DNI7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the archaeal Rpo11/eukaryotic RPB11/RPC19 RNA polymerase subunit family.
messages: Component of the RNA polymerase I (Pol I) and RNA polymerase III (Pol III) complexes consisting of at least 13 and 17 subunits, respectively.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common core component of RNA polymerases I and III which synthesize ribosomal RNA precursors and small RNAs, such as 5S rRNA and tRNAs, respectively.

219594:DACT1
gene id: 219594:DACT1
uniprot id: A0A6J3CXF9
names: Similarity
messages: Belongs to the dapper family.

219594:NAPB
gene id: 219594:NAPB
uniprot id: A0A6J3CNB4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNAP family.
messages: Membrane
messages: Required for vesicular transport between the endoplasmic reticulum and the Golgi apparatus.

219594:NELL1
gene id: 219594:NELL1
uniprot id: A0A6J3D2J4
uniprot id: A0A6J3D611
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:LOC116497748
gene id: 219594:LOC116497748
uniprot id: A0A6J3E381
names: Similarity
messages: Belongs to the 'GDXG' lipolytic enzyme family.

219594:DBH
gene id: 219594:DBH
uniprot id: A0A6J3E4I8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the copper type II ascorbate-dependent monooxygenase family.
messages: Conversion of dopamine to noradrenaline.
messages: Homotetramer; composed of two disulfide-linked dimers.
messages: chromaffin granule lumen
messages: chromaffin granule membrane
messages: secretory vesicle lumen
messages: secretory vesicle membrane

219594:ATP8B1
gene id: 219594:ATP8B1
uniprot id: A0A6J3EDU8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.
messages: Membrane

219594:ADRA1D
gene id: 219594:ADRA1D
uniprot id: A0A6J3D1E4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Interacts with FLNA (via filamin repeat 21); increases PKA-mediated phosphorylation of FLNA.
messages: Membrane
messages: This alpha-adrenergic receptor mediates its effect through the influx of extracellular calcium.

219594:PMPCA
gene id: 219594:PMPCA
uniprot id: A0A6J3E1Q7
names: Similarity
messages: Belongs to the peptidase M16 family.

219594:TM4SF4
gene id: 219594:TM4SF4
uniprot id: A0A6J3DI34
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L6 tetraspanin family.
messages: Membrane

219594:ABR
gene id: 219594:ABR
uniprot id: A0A6J3DZ79
uniprot id: A0A6J3E3G8
uniprot id: A0A6J3E4B5
names: Subcellular Location Annotation
messages: Synapse
messages: axon
messages: dendritic spine

219594:PXMP4
gene id: 219594:PXMP4
uniprot id: A0A6J3DWV5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peroxisomal membrane protein PXMP2/4 family.
messages: Interacts with PEX19.
messages: Peroxisome membrane

219594:NUDT3
gene id: 219594:NUDT3
uniprot id: A0A6J3EAP2
names: Similarity
messages: Belongs to the Nudix hydrolase family. DIPP subfamily.

219594:BRS3
gene id: 219594:BRS3
uniprot id: A0A6J3DMR0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Interacts with C6orf89.
messages: Membrane

219594:OSTC
gene id: 219594:OSTC
uniprot id: A0A6J3CYS4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OSTC family.
messages: Component of the oligosaccharyltransferase (OST) complex.
messages: Membrane
messages: Specific component of the STT3A-containing form of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All subunits are required for a maximal enzyme activity.

219594:LOC116496690
gene id: 219594:LOC116496690
uniprot id: A0A6J3E2V0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CPSF4/YTH1 family.
messages: Component of the cleavage and polyadenylation specificity factor (CPSF) complex that play a key role in pre-mRNA 3'-end formation, recognizing the AAUAAA signal sequence and interacting with poly(A) polymerase and other factors to bring about cleavage and poly(A) addition. CPSF4 binds RNA polymers with a preference for poly(U).
messages: Component of the cleavage and polyadenylation specificity factor (CPSF) complex.
messages: Nucleus

219594:RPL7L1
gene id: 219594:RPL7L1
uniprot id: A0A6J3D0P6
names: Similarity
messages: Belongs to the universal ribosomal protein uL30 family.

219594:LOC116498609
gene id: 219594:LOC116498609
uniprot id: A0A6J3E5C3
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

219594:LOC116493115
gene id: 219594:LOC116493115
uniprot id: A0A6J3DLB2
names: Similarity
messages: Belongs to the protein kinase superfamily.

219594:LOC116501059
gene id: 219594:LOC116501059
uniprot id: A0A6J3ELS0
names: Similarity
messages: Belongs to the avidin/streptavidin family.

219594:LOC116486567
gene id: 219594:LOC116486567
uniprot id: A0A6J3CJY9
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

219594:VAT1L
gene id: 219594:VAT1L
uniprot id: A0A6J3DJZ7
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily.

219594:DCLK3
gene id: 219594:DCLK3
uniprot id: A0A6J3CGE9
uniprot id: A0A6J3CI87
names: Similarity
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. CaMK subfamily.

219594:LOC116491530
gene id: 219594:LOC116491530
uniprot id: A0A6J3DB81
names: Similarity
messages: Belongs to the hexokinase family.

219594:ZEB2
gene id: 219594:ZEB2
uniprot id: A0A6J3D723
uniprot id: A0A6J3D995
names: Similarity
messages: Belongs to the delta-EF1/ZFH-1 C2H2-type zinc-finger family.

219594:TAAR1
gene id: 219594:TAAR1
uniprot id: A0A6J3CRP5
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

219594:SRD5A3
gene id: 219594:SRD5A3
uniprot id: A0A6J3CWL4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Also able to convert testosterone (T) into 5-alpha-dihydrotestosterone (DHT).
messages: Belongs to the steroid 5-alpha reductase family. Polyprenol reductase subfamily.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Plays a key role in early steps of protein N-linked glycosylation by being required for the conversion of polyprenol into dolichol. Dolichols are required for the synthesis of dolichol-linked monosaccharides and the oligosaccharide precursor used for N-glycosylation. Acts as a polyprenol reductase that promotes the reduction of the alpha-isoprene unit of polyprenols into dolichols in a NADP-dependent mechanism.

219594:LOC116501842
gene id: 219594:LOC116501842
uniprot id: A0A6J3EJC2
names: Similarity
messages: Belongs to the peptidase A1 family.

219594:ERG
gene id: 219594:ERG
uniprot id: A0A6J3EKV1
uniprot id: A0A6J3EPT3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

219594:LCOR
gene id: 219594:LCOR
uniprot id: A0A6J3D5V5
names: Subcellular Location Annotation
messages: Nucleus

219594:CHRM2
gene id: 219594:CHRM2
uniprot id: A0A6J3EJ42
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Muscarinic acetylcholine receptor subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane
messages: The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins.

219594:GPT2
gene id: 219594:GPT2
uniprot id: A0A6J3DPB9
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. Alanine aminotransferase subfamily.
messages: Homodimer.

219594:RPL8
gene id: 219594:RPL8
uniprot id: A0A6J3CRN8
names: Similarity
messages: Belongs to the universal ribosomal protein uL2 family.

219594:NAXE
gene id: 219594:NAXE
uniprot id: A0A6J3EBG9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NnrE/AIBP family.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mitochondrion
messages: Secreted

219594:GPR17
gene id: 219594:GPR17
uniprot id: A0A6J3DIX0
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

219594:EIF2B4
gene id: 219594:EIF2B4
uniprot id: A0A6J3CN25
names: Similarity
messages: Belongs to the eIF-2B alpha/beta/delta subunits family.

219594:FBN2
gene id: 219594:FBN2
uniprot id: A0A6J3ECW0
uniprot id: A0A6J3EHR6
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

219594:NDNF
gene id: 219594:NDNF
uniprot id: A0A6J3CZH6
names: Subcellular Location Annotation
messages: Secreted

219594:IL4I1
gene id: 219594:IL4I1
uniprot id: A0A6J3EGI4
names: Similarity
messages: Belongs to the flavin monoamine oxidase family.

219594:ATP2A2
gene id: 219594:ATP2A2
uniprot id: A0A6J3DWB6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIA subfamily.
messages: Catalyzes the hydrolysis of ATP coupled with the transport of calcium.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Sarcoplasmic reticulum membrane

219594:RNPEPL1
gene id: 219594:RNPEPL1
uniprot id: A0A6J3DH36
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M1 family.
messages: Binds 1 zinc ion per subunit.

219594:LOC116495131
gene id: 219594:LOC116495131
uniprot id: A0A6J3DRK6
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.

219594:COG4
gene id: 219594:COG4
uniprot id: A0A6J3DJX1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COG4 family.
messages: Golgi apparatus membrane

219594:MAPK14
gene id: 219594:MAPK14
uniprot id: A0A6J3E6Y3
names: Similarity
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MAP kinase subfamily.

219594:VWA2
gene id: 219594:VWA2
uniprot id: A0A6J3DCQ8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:LOC116501012
gene id: 219594:LOC116501012
uniprot id: A0A6J3ELL0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G protein gamma family.
messages: Cell membrane
messages: G proteins are composed of 3 units; alpha, beta and gamma.
messages: Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.

219594:STX11
gene id: 219594:STX11
uniprot id: A0A6J3CR88
names: Similarity
messages: Belongs to the syntaxin family.

219594:CA8
gene id: 219594:CA8
uniprot id: A0A6J3CMY0
names: Similarity
messages: Belongs to the alpha-carbonic anhydrase family.

219594:ATM
gene id: 219594:ATM
uniprot id: A0A6J3D4X8
uniprot id: A0A6J3D7K2
uniprot id: A0A6J3DA96
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PI3/PI4-kinase family. ATM subfamily.
messages: Nucleus

219594:NLGN1
gene id: 219594:NLGN1
uniprot id: A0A6J3DCM1
uniprot id: A0A6J3DGI7
uniprot id: A0A6J3DI60
uniprot id: A0A6J3DIQ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type-B carboxylesterase/lipase family.
messages: Cell membrane
messages: Membrane

219594:SRPRA
gene id: 219594:SRPRA
uniprot id: A0A6J3E8F0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTP-binding SRP family.
messages: Endoplasmic reticulum membrane
messages: Membrane

219594:STRN3
gene id: 219594:STRN3
uniprot id: A0A6J3D1D7
uniprot id: A0A6J3D774
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat striatin family.
messages: Membrane

219594:LOC116492484
gene id: 219594:LOC116492484
uniprot id: A0A6J3DF32
names: Similarity
messages: Belongs to the galactose-3-O-sulfotransferase family.

219594:COQ8A
gene id: 219594:COQ8A
uniprot id: A0A6J3CT09
names: Similarity
messages: Belongs to the protein kinase superfamily. ADCK protein kinase family.

219594:BCO1
gene id: 219594:BCO1
uniprot id: A0A6J3DIX4
uniprot id: A0A6J3DLF0
names: Cofactor
names: Similarity
messages: Belongs to the carotenoid oxygenase family.
messages: Binds 1 Fe(2+) ion per subunit.

219594:RFTN1
gene id: 219594:RFTN1
uniprot id: A0A6J3CNA5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the raftlin family.
messages: Cell membrane
messages: Membrane

219594:DNAJC24
gene id: 219594:DNAJC24
uniprot id: A0A6J3D1C8
names: Similarity
messages: Belongs to the DPH4 family.

219594:GSDME
gene id: 219594:GSDME
uniprot id: A0A6J3CDS3
uniprot id: A0A6J3CJZ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gasdermin family.
messages: Cell membrane
messages: Membrane

219594:LOC116489529
gene id: 219594:LOC116489529
uniprot id: A0A6J3D071
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

219594:ABCG2
gene id: 219594:ABCG2
uniprot id: A0A6J3CWR5
uniprot id: A0A6J3CX40
names: Subcellular Location Annotation
messages: Membrane

219594:FAM160B2
gene id: 219594:FAM160B2
uniprot id: A0A6J3EFB4
names: Similarity
messages: Belongs to the FHIP family.

219594:MFSD1
gene id: 219594:MFSD1
uniprot id: A0A6J3DCZ3
uniprot id: A0A6J3DGW5
uniprot id: A0A6J3DII5
names: Subcellular Location Annotation
messages: Membrane

219594:LOC116494409
gene id: 219594:LOC116494409
uniprot id: A0A6J3DQB6
uniprot id: A0A6J3DSD8
names: Similarity
messages: Belongs to the FAM122 family.

219594:ZNRF3
gene id: 219594:ZNRF3
uniprot id: A0A6J3DVP7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZNRF3 family.
messages: Cell membrane

219594:CNOT9
gene id: 219594:CNOT9
uniprot id: A0A6J3DAF5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CNOT9 family.
messages: P-body

219594:TMEM115
gene id: 219594:TMEM115
uniprot id: A0A6J3DLS1
names: Subcellular Location Annotation
messages: Membrane

219594:PRDM16
gene id: 219594:PRDM16
uniprot id: A0A6J3E0V7
uniprot id: A0A6J3E5V3
uniprot id: A0A6J3E6Z1
names: Subcellular Location Annotation
messages: Nucleus

219594:DNAH12
gene id: 219594:DNAH12
uniprot id: A0A6J3DL18
names: Similarity
messages: Belongs to the dynein heavy chain family.

219594:SLC6A14
gene id: 219594:SLC6A14
uniprot id: A0A6J3DL49
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

219594:AGPAT2
gene id: 219594:AGPAT2
uniprot id: A0A6J3E2L4
names: Domain
names: Function
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.
messages: Converts 1-acyl-sn-glycerol-3-phosphate (lysophosphatidic acid or LPA) into 1,2-diacyl-sn-glycerol-3-phosphate (phosphatidic acid or PA) by incorporating an acyl moiety at the sn-2 position of the glycerol backbone.
messages: The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate.

219594:GLI2
gene id: 219594:GLI2
uniprot id: A0A6J3DA20
names: Similarity
messages: Belongs to the GLI C2H2-type zinc-finger protein family.

219594:MTERF3
gene id: 219594:MTERF3
uniprot id: A0A6J3CLX9
names: Similarity
messages: Belongs to the mTERF family.

219594:SNX1
gene id: 219594:SNX1
uniprot id: A0A6J3DNE8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sorting nexin family.
messages: Early endosome membrane
messages: Endosome membrane
messages: Membrane
messages: lamellipodium
messages: trans-Golgi network membrane

219594:DHRS11
gene id: 219594:DHRS11
uniprot id: A0A6J3E5F4
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

219594:ANKS1B
gene id: 219594:ANKS1B
uniprot id: A0A6J3DKJ6
names: Subcellular Location Annotation
messages: Cytoplasm

219594:MRPL33
gene id: 219594:MRPL33
uniprot id: A0A6J3CWE7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

219594:LPAR4
gene id: 219594:LPAR4
uniprot id: A0A6J3DLX9
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

219594:FLNB
gene id: 219594:FLNB
uniprot id: A0A6J3DFK4
uniprot id: A0A6J3DI89
uniprot id: A0A6J3DL52
uniprot id: A0A6J3DLL9
names: Similarity
messages: Belongs to the filamin family.

219594:WNT9A
gene id: 219594:WNT9A
uniprot id: A0A6J3CIH2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

219594:DNAJC16
gene id: 219594:DNAJC16
uniprot id: A0A6J3E667
names: Function
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Plays an important role in regulating the size of autophagosomes during the formation process.

219594:GUCY1A2
gene id: 219594:GUCY1A2
uniprot id: A0A6J3EFX0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
messages: Cytoplasm

219594:DDX43
gene id: 219594:DDX43
uniprot id: A0A6J3CPS4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DEAD box helicase family.
messages: Cytoplasm

219594:SNTG2
gene id: 219594:SNTG2
uniprot id: A0A6J3CR00
uniprot id: A0A6J3CRP3
uniprot id: A0A6J3CTY8
uniprot id: A0A6J3CV36
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the syntrophin family.
messages: cytoskeleton

219594:UTP3
gene id: 219594:UTP3
uniprot id: A0A6J3CTN7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SAS10 family.
messages: nucleolus

219594:STAMBPL1
gene id: 219594:STAMBPL1
uniprot id: A0A6J3DDD4
uniprot id: A0A6J3DDR0
names: Similarity
messages: Belongs to the peptidase M67C family.

219594:C1H12orf75
gene id: 219594:C1H12orf75
uniprot id: A0A6J3EIE4
uniprot id: A0A6J3ENL3
names: Similarity
messages: Belongs to the OCC1 family.

219594:GRK5
gene id: 219594:GRK5
uniprot id: A0A6J3D614
uniprot id: A0A6J3DBX9
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily.

219594:LOC116487932
gene id: 219594:LOC116487932
uniprot id: A0A6J3CVW5
names: Similarity
messages: Belongs to the major facilitator (TC 2.A.1) superfamily. Organic cation transporter (TC 2.A.1.19) family.

219594:MMAA
gene id: 219594:MMAA
uniprot id: A0A6J3CVZ4
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ArgK/MeaB subfamily.

219594:CTNNBL1
gene id: 219594:CTNNBL1
uniprot id: A0A6J3DS20
names: Subcellular Location Annotation
messages: Nucleus

219594:NDUFA10
gene id: 219594:NDUFA10
uniprot id: A0A6J3D7F9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFA10 subunit family.
messages: Complex I is composed of 45 different subunits. This a component of the hydrophobic protein fraction.
messages: Mitochondrion matrix

219594:PPP1R2
gene id: 219594:PPP1R2
uniprot id: A0A6J3DCZ0
uniprot id: A0A6J3DII0
uniprot id: A0A6J3DJ34
names: Similarity
messages: Belongs to the protein phosphatase inhibitor 2 family.

219594:GPT
gene id: 219594:GPT
uniprot id: A0A6J3CL53
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. Alanine aminotransferase subfamily.
messages: Homodimer.

219594:LOC116499992
gene id: 219594:LOC116499992
uniprot id: A0A6J3EFF5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.
messages: cytoskeleton

219594:CRHR2
gene id: 219594:CRHR2
uniprot id: A0A6J3CLJ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 2 family.
messages: Membrane

219594:CAB39
gene id: 219594:CAB39
uniprot id: A0A6J3DFZ8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mo25 family.
messages: Component of a complex that binds and activates STK11/LKB1. In the complex, required to stabilize the interaction between CAB39/MO25 (CAB39/MO25alpha or CAB39L/MO25beta) and STK11/LKB1.
messages: Component of a trimeric complex composed of STK11/LKB1, STRAD (STRADA or STRADB) and CAB39/MO25 (CAB39/MO25alpha or CAB39L/MO25beta): the complex tethers STK11/LKB1 in the cytoplasm and stimulates its catalytic activity.

219594:UBAP2L
gene id: 219594:UBAP2L
uniprot id: A0A6J3E9M5
uniprot id: A0A6J3EB33
uniprot id: A0A6J3EED4
uniprot id: A0A6J3EER1
uniprot id: A0A6J3EGE9
names: Subcellular Location Annotation
messages: Cytoplasm

219594:MINAR1
gene id: 219594:MINAR1
uniprot id: A0A6J3DLS6
names: Similarity
messages: Belongs to the MINAR family.

219594:TNFSF11
gene id: 219594:TNFSF11
uniprot id: A0A6J3EJF8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tumor necrosis factor family.
messages: Membrane
messages: Secreted

219594:LOC116486883
gene id: 219594:LOC116486883
uniprot id: A0A6J3CJZ9
names: Similarity
names: Subunit
messages: Belongs to the avian keratin family.
messages: The avian keratins (F-ker, S-ker, C-ker and B-ker) are a complex mixture of very similar polypeptides.

219594:KCNH8
gene id: 219594:KCNH8
uniprot id: A0A6J3CM68
names: Subcellular Location Annotation
names: Subunit
messages: Membrane
messages: The potassium channel is probably composed of a homo- or heterotetrameric complex of pore-forming alpha subunits that can associate with modulating beta subunits.

219594:TCTEX1D1
gene id: 219594:TCTEX1D1
uniprot id: A0A6J3DF91
names: Similarity
messages: Belongs to the dynein light chain Tctex-type family.

219594:EIF3J
gene id: 219594:EIF3J
uniprot id: A0A6J3DIU8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-3 subunit J family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is composed of 13 subunits: EIF3A, EIF3B, EIF3C, EIF3D, EIF3E, EIF3F, EIF3G, EIF3H, EIF3I, EIF3J, EIF3K, EIF3L and EIF3M.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
messages: Cytoplasm

219594:SLC30A4
gene id: 219594:SLC30A4
uniprot id: A0A6J3DJE7
uniprot id: A0A6J3DMV3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily.
messages: Membrane

219594:SYT1
gene id: 219594:SYT1
uniprot id: A0A6J3CP00
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptotagmin family.
messages: Binds 3 Ca(2+) ions per subunit. The ions are bound to the C2 domains.
messages: May have a regulatory role in the membrane interactions during trafficking of synaptic vesicles at the active zone of the synapse. It binds acidic phospholipids with a specificity that requires the presence of both an acidic head group and a diacyl backbone.
messages: synaptic vesicle membrane

219594:NEMP2
gene id: 219594:NEMP2
uniprot id: A0A6J3D8H1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NEMP family.
messages: Nucleus inner membrane

219594:TNFRSF1A
gene id: 219594:TNFRSF1A
uniprot id: A0A6J3DZC4
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:MRPS31
gene id: 219594:MRPS31
uniprot id: A0A6J3EJT7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mS31 family.
messages: Mitochondrion

219594:GPR146
gene id: 219594:GPR146
uniprot id: A0A6J3DQU5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

219594:TUBGCP6
gene id: 219594:TUBGCP6
uniprot id: A0A6J3DX89
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TUBGCP family.
messages: centrosome

219594:NDUFB10
gene id: 219594:NDUFB10
uniprot id: A0A6J3DU36
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Accessory subunit that is involved in the functional assembly of the mitochondrial respiratory chain complex I. Complex I has an NADH dehydrogenase activity with ubiquinone as an immediate electron acceptor and mediates the transfer of electrons from NADH to the respiratory chain.
messages: Belongs to the complex I NDUFB10 subunit family.
messages: Mitochondrion inner membrane

219594:TPST2
gene id: 219594:TPST2
uniprot id: A0A6J3DVZ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein sulfotransferase family.
messages: Catalyzes the O-sulfation of tyrosine residues within acidic motifs of polypeptides, using 3'-phosphoadenylyl sulfate (PAPS) as cosubstrate.
messages: Golgi apparatus membrane

219594:AFG1L
gene id: 219594:AFG1L
uniprot id: A0A6J3CPC8
names: Similarity
messages: Belongs to the AFG1 ATPase family.

219594:RPS11
gene id: 219594:RPS11
uniprot id: A0A6J3DK31
names: Similarity
messages: Belongs to the universal ribosomal protein uS17 family.

219594:OPA1
gene id: 219594:OPA1
uniprot id: A0A6J3DBL7
uniprot id: A0A6J3DE81
uniprot id: A0A6J3DFD5
uniprot id: A0A6J3DH49
names: Subcellular Location Annotation
messages: Membrane
messages: Mitochondrion inner membrane
messages: Mitochondrion membrane

219594:ARPC5L
gene id: 219594:ARPC5L
uniprot id: A0A6J3DXM0
names: Function
names: Similarity
messages: Belongs to the ARPC5 family.
messages: Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development.

219594:PGM2
gene id: 219594:PGM2
uniprot id: A0A6J3CX54
names: Similarity
messages: Belongs to the phosphohexose mutase family.

219594:SMU1
gene id: 219594:SMU1
uniprot id: A0A6J3EIC7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat SMU1 family.
messages: Nucleus speckle

219594:INSIG2
gene id: 219594:INSIG2
uniprot id: A0A6J3D6S2
uniprot id: A0A6J3D9H9
uniprot id: A0A6J3DA25
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the INSIG family.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mediates feedback control of cholesterol synthesis.
messages: Membrane

219594:KCNK18
gene id: 219594:KCNK18
uniprot id: A0A6J3D7Z1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
messages: Membrane

219594:TMEM39A
gene id: 219594:TMEM39A
uniprot id: A0A6J3D604
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM39 family.
messages: Membrane

219594:LOC116491877
gene id: 219594:LOC116491877
uniprot id: A0A6J3DC98
names: Similarity
messages: Belongs to the amidase family.

219594:SLC24A4
gene id: 219594:SLC24A4
uniprot id: A0A6J3D1P8
uniprot id: A0A6J3D6N7
uniprot id: A0A6J3D7I1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. SLC24A subfamily.
messages: Membrane

219594:CRMP1
gene id: 219594:CRMP1
uniprot id: A0A6J3CVH8
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Hydantoinase/dihydropyrimidinase family.

219594:AFMID
gene id: 219594:AFMID
uniprot id: A0A6J3E104
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the kynurenine formamidase family.
messages: Catalyzes the hydrolysis of N-formyl-L-kynurenine to L-kynurenine, the second step in the kynurenine pathway of tryptophan degradation. Kynurenine may be further oxidized to nicotinic acid, NAD(H) and NADP(H). Required for elimination of toxic metabolites.
messages: Homodimer.
messages: Nucleus
messages: The main chain amide nitrogen atoms of the second glycine and its adjacent residue in the HGGXW motif define the oxyanion hole, and stabilize the oxyanion that forms during the nucleophilic attack by the catalytic serine during substrate cleavage.
messages: cytosol

219594:ANAPC11
gene id: 219594:ANAPC11
uniprot id: A0A6J3DW76
names: Similarity
messages: Belongs to the RING-box family.

219594:HRH2
gene id: 219594:HRH2
uniprot id: A0A6J3DTC1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

219594:LOC116502225
gene id: 219594:LOC116502225
uniprot id: A0A6J3EKV6
uniprot id: A0A6J3ERA3
names: Subcellular Location Annotation
messages: Membrane

219594:LOC116494373
gene id: 219594:LOC116494373
uniprot id: A0A6J3DKW7
uniprot id: A0A6J3DNC1
uniprot id: A0A6J3DRA2
uniprot id: A0A6J3DS77
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chloride channel (TC 2.A.49) family. ClC-5/CLCN5 subfamily.
messages: Cell membrane
messages: Endosome membrane
messages: Golgi apparatus membrane
messages: Interacts with NEDD4 and NEDD4L.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

219594:GLB1L
gene id: 219594:GLB1L
uniprot id: A0A6J3D2R5
uniprot id: A0A6J3D8M0
names: Similarity
messages: Belongs to the glycosyl hydrolase 35 family.

219594:RRS1
gene id: 219594:RRS1
uniprot id: A0A6J3CHY3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRS1 family.
messages: Involved in ribosomal large subunit assembly.
messages: Nucleus

219594:SLC1A3
gene id: 219594:SLC1A3
uniprot id: A0A6J3EI38
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Membrane

219594:LOC116487604
gene id: 219594:LOC116487604
uniprot id: A0A6J3CT93
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CENP-Q/OKP1 family.
messages: Nucleus

219594:PNRC1
gene id: 219594:PNRC1
uniprot id: A0A6J3CUL3
names: Subcellular Location Annotation
messages: Nucleus

219594:LOC116493153
gene id: 219594:LOC116493153
uniprot id: A0A6J3DFD2
names: Similarity
messages: Belongs to the FAM20 family.

219594:GANC
gene id: 219594:GANC
uniprot id: A0A6J3D5G6
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.

219594:RIBC2
gene id: 219594:RIBC2
uniprot id: A0A6J3ENC2
names: Similarity
messages: Belongs to the RIB43A family.

219594:SMO
gene id: 219594:SMO
uniprot id: A0A6J3DVE8
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor Fz/Smo family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: cilium

219594:GIPC2
gene id: 219594:GIPC2
uniprot id: A0A6J3DEL0
uniprot id: A0A6J3DGR9
names: Similarity
messages: Belongs to the GIPC family.

219594:LOC116492509
gene id: 219594:LOC116492509
uniprot id: A0A6J3DF58
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the alkaline phosphatase family.
messages: Binds 1 Mg(2+) ion.
messages: Binds 2 Zn(2+) ions.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

219594:ABCC3
gene id: 219594:ABCC3
uniprot id: A0A6J3DY75
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCC family. Conjugate transporter (TC 3.A.1.208) subfamily.
messages: Cell membrane
messages: Membrane

219594:LOC116485640
gene id: 219594:LOC116485640
uniprot id: A0A6J3CHX8
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion.
messages: desmosome

219594:LOC116500210
gene id: 219594:LOC116500210
uniprot id: A0A6J3EG56
names: Subcellular Location Annotation
messages: extracellular matrix

219594:PARP4
gene id: 219594:PARP4
uniprot id: A0A6J3DJW8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ARTD/PARP family.
messages: Nucleus

219594:ZDHHC17
gene id: 219594:ZDHHC17
uniprot id: A0A6J3CIU5
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Cytoplasmic vesicle membrane
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

219594:CPLX2
gene id: 219594:CPLX2
uniprot id: A0A6J3DQK6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complexin/synaphin family.
messages: Synapse

219594:LOC116499792
gene id: 219594:LOC116499792
uniprot id: A0A6J3EGR9
names: Similarity
messages: Belongs to the avian keratin family.

219594:ADPRS
gene id: 219594:ADPRS
uniprot id: A0A6J3E838
names: Similarity
messages: Belongs to the ADP-ribosylglycohydrolase family.

219594:CACHD1
gene id: 219594:CACHD1
uniprot id: A0A6J3DD68
names: Similarity
messages: Belongs to the calcium channel subunit alpha-2/delta family.

219594:LOC116492642
gene id: 219594:LOC116492642
uniprot id: A0A6J3DGZ5
names: Subcellular Location Annotation
messages: Membrane

219594:LOC116492398
gene id: 219594:LOC116492398
uniprot id: A0A6J3DBZ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ubiquitin family. SUMO subfamily.
messages: Nucleus

219594:GNG5
gene id: 219594:GNG5
uniprot id: A0A6J3DFT7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G protein gamma family.
messages: Cell membrane
messages: G proteins are composed of 3 units; alpha, beta and gamma.
messages: Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.

219594:BOD1
gene id: 219594:BOD1
uniprot id: A0A6J3DQR4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BOD1 family.
messages: centrosome
messages: kinetochore

219594:SFRP5
gene id: 219594:SFRP5
uniprot id: A0A6J3DBA9
names: Caution
names: Similarity
messages: Belongs to the secreted frizzled-related protein (sFRP) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:LOC116490916
gene id: 219594:LOC116490916
uniprot id: A0A6J3D4W8
uniprot id: A0A6J3D833
names: Similarity
messages: Belongs to the GroES chaperonin family.

219594:DDOST
gene id: 219594:DDOST
uniprot id: A0A6J3E806
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DDOST 48 kDa subunit family.
messages: Component of the oligosaccharyltransferase (OST) complex.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER).

219594:PRDM13
gene id: 219594:PRDM13
uniprot id: A0A6J3CTV3
names: Subcellular Location Annotation
messages: Nucleus

219594:LOC116501315
gene id: 219594:LOC116501315
uniprot id: A0A6J3EHM8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:C15H16orf71
gene id: 219594:C15H16orf71
uniprot id: A0A6J3DSL8
names: Function
names: Subcellular Location Annotation
messages: Dynein axonemal particle
messages: In cyliated cells, dynein axonemal particle-specific protein required for deployment of ODA to the axoneme. Interacts with outer dynein arm (ODA) subunits.

219594:CDC42SE2
gene id: 219594:CDC42SE2
uniprot id: A0A6J3EJD7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDC42SE/SPEC family.
messages: Cell membrane
messages: Membrane
messages: cytoskeleton

219594:STXBP3
gene id: 219594:STXBP3
uniprot id: A0A6J3DCV4
names: Similarity
messages: Belongs to the STXBP/unc-18/SEC1 family.

219594:LOC116491122
gene id: 219594:LOC116491122
uniprot id: A0A6J3D8I0
names: Similarity
messages: Belongs to the AB hydrolase superfamily. Lipase family.

219594:ARID5B
gene id: 219594:ARID5B
uniprot id: A0A6J3D6E7
uniprot id: A0A6J3D9P8
uniprot id: A0A6J3DBW8
names: Similarity
messages: Belongs to the ARID5B family.

219594:LRP2
gene id: 219594:LRP2
uniprot id: A0A6J3D8R4
names: Caution
names: Similarity
messages: Belongs to the LDLR family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:PTPRK
gene id: 219594:PTPRK
uniprot id: A0A6J3CQ65
uniprot id: A0A6J3CQ70
uniprot id: A0A6J3CQW3
uniprot id: A0A6J3CQW9
uniprot id: A0A6J3CT69
uniprot id: A0A6J3CT74
uniprot id: A0A6J3CUA9
uniprot id: A0A6J3CUB4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Receptor class 2B subfamily.
messages: Membrane

219594:NUP107
gene id: 219594:NUP107
uniprot id: A0A6J3EBT2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the nucleoporin Nup84/Nup107 family.
messages: Functions as a component of the nuclear pore complex (NPC).
messages: Nucleus membrane
messages: Part of the nuclear pore complex (NPC).
messages: nuclear pore complex

219594:FRRS1
gene id: 219594:FRRS1
uniprot id: A0A6J3DB35
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FRRS1 family.
messages: Membrane

219594:DTYMK
gene id: 219594:DTYMK
uniprot id: A0A6J3DFT8
names: Similarity
messages: Belongs to the thymidylate kinase family.

219594:INPPL1
gene id: 219594:INPPL1
uniprot id: A0A6J3EQM6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inositol 1,4,5-trisphosphate 5-phosphatase family.
messages: Membrane
messages: Nucleus speckle
messages: filopodium
messages: lamellipodium

219594:LOC116494568
gene id: 219594:LOC116494568
uniprot id: A0A6J3DRY1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SCAR/WAVE family.
messages: Binds actin and the Arp2/3 complex.
messages: Downstream effector molecule involved in the transmission of signals from tyrosine kinase receptors and small GTPases to the actin cytoskeleton. Promotes formation of actin filaments. Part of the WAVE complex that regulates lamellipodia formation. The WAVE complex regulates actin filament reorganization via its interaction with the Arp2/3 complex.
messages: cytoskeleton

219594:TMEM120B
gene id: 219594:TMEM120B
uniprot id: A0A6J3DXY8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM120 family.
messages: Membrane
messages: Nucleus inner membrane

219594:MRPS33
gene id: 219594:MRPS33
uniprot id: A0A6J3EAF9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mS33 family.
messages: Mitochondrion

219594:SLC17A5
gene id: 219594:SLC17A5
uniprot id: A0A6J3CNP2
names: Subcellular Location Annotation
messages: Membrane

219594:SYS1
gene id: 219594:SYS1
uniprot id: A0A6J3DU18
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SYS1 family.
messages: Golgi apparatus membrane
messages: Interacts with ARFRP1.
messages: Involved in protein trafficking. May serve as a receptor for ARFRP1.
messages: Membrane

219594:ETF1
gene id: 219594:ETF1
uniprot id: A0A6J3DSD9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic release factor 1 family.
messages: Cytoplasm

219594:LOC116497136
gene id: 219594:LOC116497136
uniprot id: A0A6J3E0I6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2B family.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

219594:MAN1A2
gene id: 219594:MAN1A2
uniprot id: A0A6J3CKD0
names: Similarity
messages: Belongs to the glycosyl hydrolase 47 family.

219594:GRK6
gene id: 219594:GRK6
uniprot id: A0A6J3DQ11
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily.

219594:RC3H1
gene id: 219594:RC3H1
uniprot id: A0A6J3DDA0
uniprot id: A0A6J3DEC2
uniprot id: A0A6J3DEC7
uniprot id: A0A6J3DGH5
names: Subcellular Location Annotation
messages: P-body

219594:LOC116497193
gene id: 219594:LOC116497193
uniprot id: A0A6J3DZA3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the archaeal Rpo11/eukaryotic RPB11/RPC19 RNA polymerase subunit family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase II which synthesizes mRNA precursors and many functional non-coding RNAs. Pol II is the central component of the basal RNA polymerase II transcription machinery. It is composed of mobile elements that move relative to each other. RPB11 is part of the core element with the central large cleft.
messages: Nucleus

219594:SEC31B
gene id: 219594:SEC31B
uniprot id: A0A6J3D9R1
uniprot id: A0A6J3DAE7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat SEC31 family.
messages: Endoplasmic reticulum membrane

219594:LOC116489463
gene id: 219594:LOC116489463
uniprot id: A0A6J3CZU7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ITPRIP family.
messages: Membrane

219594:MBTPS2
gene id: 219594:MBTPS2
uniprot id: A0A6J3D0S2
uniprot id: A0A6J3D0T7
names: Similarity
messages: Belongs to the peptidase M50A family.

219594:SNRPG
gene id: 219594:SNRPG
uniprot id: A0A6J3EFB8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the snRNP Sm proteins family.
messages: Nucleus

219594:FUNDC2
gene id: 219594:FUNDC2
uniprot id: A0A6J3DKY8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FUN14 family.
messages: Mitochondrion outer membrane

219594:CD5
gene id: 219594:CD5
uniprot id: A0A6J3D041
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:SLC44A3
gene id: 219594:SLC44A3
uniprot id: A0A6J3DAH1
uniprot id: A0A6J3DD33
uniprot id: A0A6J3DG63
uniprot id: A0A6J3DGA2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CTL (choline transporter-like) family.
messages: Cell membrane
messages: Choline transporter.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

219594:GDF9
gene id: 219594:GDF9
uniprot id: A0A6J3DS73
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TGF-beta family.
messages: Homodimer or heterodimer (Potential). But, in contrast to other members of this family, cannot be disulfide-linked.
messages: Secreted

219594:TMEM234
gene id: 219594:TMEM234
uniprot id: A0A6J3E3F4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM234 family.
messages: Membrane

219594:TMEM18
gene id: 219594:TMEM18
uniprot id: A0A6J3CQT4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM18 family.
messages: Membrane
messages: Nucleus membrane

219594:MPHOSPH10
gene id: 219594:MPHOSPH10
uniprot id: A0A6J3DKX6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MPP10 family.
messages: Component of the 60-80S U3 small nucleolar ribonucleoprotein (U3 snoRNP). Required for the early cleavages during pre-18S ribosomal RNA processing.
messages: nucleolus

219594:POLR1B
gene id: 219594:POLR1B
uniprot id: A0A6J3CPT4
names: Function
names: Similarity
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Second largest core component of RNA polymerase I which synthesizes ribosomal RNA precursors. Proposed to contribute to the polymerase catalytic activity and forms the polymerase active center together with the largest subunit. Pol I is composed of mobile elements and RPA2 is part of the core element with the central large cleft and probably a clamp element that moves to open and close the cleft.

219594:NAB1
gene id: 219594:NAB1
uniprot id: A0A6J3D3K0
uniprot id: A0A6J3D653
uniprot id: A0A6J3D6N0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NAB family.
messages: Homomultimers may associate with EGR1 bound to DNA.
messages: Nucleus

219594:PITPNM3
gene id: 219594:PITPNM3
uniprot id: A0A6J3E1X3
uniprot id: A0A6J3E6L8
names: Similarity
messages: Belongs to the PtdIns transfer protein family. PI transfer class IIA subfamily.

219594:LMNB1
gene id: 219594:LMNB1
uniprot id: A0A6J3EM23
names: Similarity
messages: Belongs to the intermediate filament family.

219594:KDM1A
gene id: 219594:KDM1A
uniprot id: A0A6J3E4D6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the flavin monoamine oxidase family.
messages: Histone demethylase that can demethylate both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me. May play a role in the repression of neuronal genes. Alone, it is unable to demethylate H3K4me on nucleosomes and requires the presence of RCOR1/CoREST to achieve such activity.
messages: Nucleus
messages: The SWIRM domain may act as an anchor site for a histone tail.

219594:LOC116500322
gene id: 219594:LOC116500322
uniprot id: A0A6J3EBS6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

219594:LOC116500889
gene id: 219594:LOC116500889
uniprot id: A0A6J3EJG5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the intercrine beta (chemokine CC) family.
messages: Secreted

219594:INSIG1
gene id: 219594:INSIG1
uniprot id: A0A6J3CLJ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the INSIG family.
messages: Endoplasmic reticulum membrane
messages: Mediates feedback control of cholesterol synthesis.
messages: Membrane

219594:CNIH4
gene id: 219594:CNIH4
uniprot id: A0A6J3CVX7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cornichon family.
messages: Membrane

219594:PGAP6
gene id: 219594:PGAP6
uniprot id: A0A6J3DQA8
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM8 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

219594:KRTCAP3
gene id: 219594:KRTCAP3
uniprot id: A0A6J3CND1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM54 family.
messages: Membrane

219594:LOC116498061
gene id: 219594:LOC116498061
uniprot id: A0A6J3E4V3
uniprot id: A0A6J3E9U4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CYRI family.
messages: Membrane

219594:VPS35
gene id: 219594:VPS35
uniprot id: A0A6J3DMN0
names: Function
names: Similarity
messages: Belongs to the VPS35 family.
messages: Plays a role in vesicular protein sorting.

219594:DNAJA1
gene id: 219594:DNAJA1
uniprot id: A0A6J3EJ20
names: Subcellular Location Annotation
messages: Membrane

219594:PLXND1
gene id: 219594:PLXND1
uniprot id: A0A6J3DJA3
names: Caution
names: Similarity
messages: Belongs to the plexin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:NDUFA8
gene id: 219594:NDUFA8
uniprot id: A0A6J3E1S9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFA8 subunit family.
messages: Mitochondrion inner membrane
messages: Mitochondrion intermembrane space

219594:MTCL1
gene id: 219594:MTCL1
uniprot id: A0A6J3CDD6
names: Similarity
messages: Belongs to the SOGA family.

219594:LOC116500050
gene id: 219594:LOC116500050
uniprot id: A0A6J3EAX1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane

219594:AQP9
gene id: 219594:AQP9
uniprot id: A0A6J3DJ22
uniprot id: A0A6J3DME8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Cell membrane
messages: Membrane

219594:TACC3
gene id: 219594:TACC3
uniprot id: A0A6J3CXZ5
uniprot id: A0A6J3CYA8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACC family.
messages: Cytoplasm

219594:IRX1
gene id: 219594:IRX1
uniprot id: A0A6J3CJP4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TALE/IRO homeobox family.
messages: Nucleus

219594:ST8SIA6
gene id: 219594:ST8SIA6
uniprot id: A0A6J3CK59
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

219594:PROS1
gene id: 219594:PROS1
uniprot id: A0A6J3CKI6
uniprot id: A0A6J3CKJ7
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:CCR8
gene id: 219594:CCR8
uniprot id: A0A6J3CHS3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Early endosome
messages: Endosome
messages: Membrane

219594:LOC116502371
gene id: 219594:LOC116502371
uniprot id: A0A6J3EK20
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2A family.
messages: Chromosome
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

219594:CTU2
gene id: 219594:CTU2
uniprot id: A0A6J3DQ60
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CTU2/NCS2 family.
messages: Cytoplasm
messages: Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln). May act by forming a heterodimer with CTU1/ATPBD3 that ligates sulfur from thiocarboxylated URM1 onto the uridine of tRNAs at wobble position.

219594:ELAVL2
gene id: 219594:ELAVL2
uniprot id: A0A6J3EC17
uniprot id: A0A6J3EDE0
uniprot id: A0A6J3EGU0
uniprot id: A0A6J3EGU5
uniprot id: A0A6J3EGV5
uniprot id: A0A6J3EH26
uniprot id: A0A6J3EH31
uniprot id: A0A6J3EIP4
uniprot id: A0A6J3EIQ0
names: Similarity
messages: Belongs to the RRM elav family.

219594:CCNY
gene id: 219594:CCNY
uniprot id: A0A6J3CHX7
uniprot id: A0A6J3CIY6
names: Similarity
messages: Belongs to the cyclin family. Cyclin Y subfamily.

219594:LOC116487531
gene id: 219594:LOC116487531
uniprot id: A0A6J3CMZ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. Very large inducible GTPase (VLIG) family.
messages: Nucleus

219594:AMOTL1
gene id: 219594:AMOTL1
uniprot id: A0A6J3E7N2
uniprot id: A0A6J3ECW5
names: Similarity
messages: Belongs to the angiomotin family.

219594:TMEM198
gene id: 219594:TMEM198
uniprot id: A0A6J3D4S3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM198 family.
messages: Membrane

219594:LOC116497550
gene id: 219594:LOC116497550
uniprot id: A0A6J3E723
names: Similarity
messages: Belongs to the 'GDXG' lipolytic enzyme family.

219594:DEF8
gene id: 219594:DEF8
uniprot id: A0A6J3DR54
names: Similarity
messages: Belongs to the DEF8 family.

219594:UBE3D
gene id: 219594:UBE3D
uniprot id: A0A6J3CMU7
names: Function
messages: E3 ubiquitin-protein ligase which accepts ubiquitin from specific E2 ubiquitin-conjugating enzymes, and transfers it to substrates, generally promoting their degradation by the proteasome.

219594:LOC116501268
gene id: 219594:LOC116501268
uniprot id: A0A6J3ELA0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the beta type-B retroviral polymerase family. HERV class-II K(HML-2) pol subfamily.
messages: Nucleus

219594:BOLA3
gene id: 219594:BOLA3
uniprot id: A0A6J3EFG7
names: Similarity
messages: Belongs to the BolA/IbaG family.

219594:XG
gene id: 219594:XG
uniprot id: A0A6J3DZL8
names: Similarity
messages: Belongs to the CD99 family.

219594:DNTTIP2
gene id: 219594:DNTTIP2
uniprot id: A0A6J3DFM1
names: Subcellular Location Annotation
messages: nucleolus

219594:PHC1
gene id: 219594:PHC1
uniprot id: A0A6J3D7U2
uniprot id: A0A6J3D7V0
uniprot id: A0A6J3DDD9
names: Subcellular Location Annotation
messages: Nucleus

219594:ZIC2
gene id: 219594:ZIC2
uniprot id: A0A6J3DQ83
names: Similarity
messages: Belongs to the GLI C2H2-type zinc-finger protein family.

219594:EVA1B
gene id: 219594:EVA1B
uniprot id: A0A6J3E900
names: Similarity
messages: Belongs to the EVA1 family.

219594:RPL36
gene id: 219594:RPL36
uniprot id: A0A6J3EBV1
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL36 family.

219594:EFHB
gene id: 219594:EFHB
uniprot id: A0A6J3CDS0
names: Subcellular Location Annotation
messages: cilium axoneme

219594:SPTBN5
gene id: 219594:SPTBN5
uniprot id: A0A6J3D504
names: Similarity
messages: Belongs to the spectrin family.

219594:NR6A1
gene id: 219594:NR6A1
uniprot id: A0A6J3E2I7
uniprot id: A0A6J3E3C4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

219594:ATP5MC1
gene id: 219594:ATP5MC1
uniprot id: A0A6J3E4K2
uniprot id: A0A6J3E5Y5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Membrane
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain. A homomeric c-ring of probably 10 subunits is part of the complex rotary element.
messages: Mitochondrion membrane

219594:SPAST
gene id: 219594:SPAST
uniprot id: A0A6J3CPK6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent microtubule severing protein that specifically recognizes and cuts microtubules that are polyglutamylated. Preferentially recognizes and acts on microtubules decorated with short polyglutamate tails: severing activity increases as the number of glutamates per tubulin rises from one to eight, but decreases beyond this glutamylation threshold. Microtubule severing promotes reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation. Required for membrane traffic from the endoplasmic reticulum (ER) to the Golgi and for completion of the abscission stage of cytokinesis. Also plays a role in axon growth and the formation of axonal branches.
messages: Belongs to the AAA ATPase family. Spastin subfamily.
messages: Homohexamer. The homohexamer is stabilized by ATP-binding. The homohexamer may adopt a ring conformation through which microtubules pass prior to being severed. Interacts with microtubules.
messages: Membrane
messages: Nucleus
messages: axon
messages: centrosome
messages: cytoskeleton
messages: perinuclear region

219594:ALG6
gene id: 219594:ALG6
uniprot id: A0A6J3DDW2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ALG6/ALG8 glucosyltransferase family.
messages: Endoplasmic reticulum membrane
messages: Membrane

219594:PROM2
gene id: 219594:PROM2
uniprot id: A0A6J3E8P6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prominin family.
messages: Membrane
messages: microvillus membrane

219594:C1GALT1
gene id: 219594:C1GALT1
uniprot id: A0A6J3CFB5
names: Subcellular Location Annotation
messages: Membrane

219594:LOC116500151
gene id: 219594:LOC116500151
uniprot id: A0A6J3EBB6
names: Subcellular Location Annotation
messages: Membrane

219594:ABCB6
gene id: 219594:ABCB6
uniprot id: A0A6J3D9H1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. ABCB family. Heavy Metal importer (TC 3.A.1.210) subfamily.
messages: Early endosome membrane
messages: Endosome membrane
messages: Golgi apparatus membrane
messages: Homodimer.
messages: Late endosome membrane
messages: Lysosome membrane
messages: Melanosome membrane
messages: Membrane
messages: Mitochondrion outer membrane
messages: extracellular exosome
messages: multivesicular body membrane

219594:GCHFR
gene id: 219594:GCHFR
uniprot id: A0A6J3CX29
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GFRP family.
messages: Membrane
messages: Nucleus membrane
messages: cytosol

219594:PTBP1
gene id: 219594:PTBP1
uniprot id: A0A6J3EBG7
uniprot id: A0A6J3EBZ7
names: Subcellular Location Annotation
messages: Nucleus

219594:OTULIN
gene id: 219594:OTULIN
uniprot id: A0A6J3CID6
uniprot id: A0A6J3CM00
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C65 family. Otulin subfamily.
messages: Cytoplasm

219594:DPYSL4
gene id: 219594:DPYSL4
uniprot id: A0A6J3DD87
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Hydantoinase/dihydropyrimidinase family.

219594:LHFPL4
gene id: 219594:LHFPL4
uniprot id: A0A6J3DIJ2
names: Subcellular Location Annotation
messages: Membrane

219594:LOC116500823
gene id: 219594:LOC116500823
uniprot id: A0A6J3EFI4
names: Similarity
messages: Belongs to the cystatin family.

219594:LOC116500794
gene id: 219594:LOC116500794
uniprot id: A0A6J3EDY2
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:FBXO34
gene id: 219594:FBXO34
uniprot id: A0A6J3D1U4
names: Function
messages: Substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex.

219594:LOC116500598
gene id: 219594:LOC116500598
uniprot id: A0A6J3ED04
uniprot id: A0A6J3EI57
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

219594:NDST1
gene id: 219594:NDST1
uniprot id: A0A6J3DTN0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 1 family. NDST subfamily.
messages: Membrane

219594:POLL
gene id: 219594:POLL
uniprot id: A0A6J3DB89
uniprot id: A0A6J3DBR0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-X family.
messages: Nucleus

219594:MSTN
gene id: 219594:MSTN
uniprot id: A0A6J3DA72
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts specifically as a negative regulator of skeletal muscle growth.
messages: Belongs to the TGF-beta family.
messages: Homodimer; disulfide-linked.
messages: Secreted

219594:LOC116492933
gene id: 219594:LOC116492933
uniprot id: A0A6J3DH41
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

219594:ADPRM
gene id: 219594:ADPRM
uniprot id: A0A6J3DYI2
names: Similarity
names: Subunit
messages: Belongs to the ADPRibase-Mn family.
messages: Monomer.

219594:TMEM17
gene id: 219594:TMEM17
uniprot id: A0A6J3CRU0
names: Subcellular Location Annotation
messages: Membrane

219594:MELTF
gene id: 219594:MELTF
uniprot id: A0A6J3DJ16
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transferrin family.
messages: Monomer.
messages: Secreted

219594:TAS1R3
gene id: 219594:TAS1R3
uniprot id: A0A6J3E233
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

219594:RBKS
gene id: 219594:RBKS
uniprot id: A0A6J3CQ97
names: Activity Regulation
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.
messages: Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.
messages: Belongs to the carbohydrate kinase pfkB family.
messages: Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus
messages: Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate.

219594:XPC
gene id: 219594:XPC
uniprot id: A0A6J3DIB4
uniprot id: A0A6J3DLP5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the XPC family.
messages: Nucleus

219594:MAK16
gene id: 219594:MAK16
uniprot id: A0A6J3EFK8
names: Similarity
messages: Belongs to the MAK16 family.

219594:IDH2
gene id: 219594:IDH2
uniprot id: A0A6J3DJG4
names: Cofactor
names: Similarity
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

219594:MRPL32
gene id: 219594:MRPL32
uniprot id: A0A6J3CFV6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

219594:PTCH2
gene id: 219594:PTCH2
uniprot id: A0A6J3D9M5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the patched family.
messages: Membrane

219594:LIMK1
gene id: 219594:LIMK1
uniprot id: A0A6J3E4H9
names: Similarity
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family.

219594:CSGALNACT2
gene id: 219594:CSGALNACT2
uniprot id: A0A6J3DCT3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chondroitin N-acetylgalactosaminyltransferase family.
messages: Golgi stack membrane
messages: Membrane

219594:KATNAL1
gene id: 219594:KATNAL1
uniprot id: A0A6J3ER07
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATPase activity is stimulated by microtubules, which promote homooligomerization. ATP-dependent microtubule severing is stimulated by interaction with KATNB1.
messages: Belongs to the AAA ATPase family. Katanin p60 subunit A1 subfamily. A-like 1 sub-subfamily.
messages: Can homooligomerize into hexameric rings, which may be promoted by interaction with microtubules. Interacts with KATNB1, which may serve as a targeting subunit.
messages: Catalytic subunit of a complex which severs microtubules in an ATP-dependent manner. Microtubule severing may promote rapid reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation.
messages: Cytoplasm
messages: Interacts with KATNB1 and KATNBL1.
messages: Regulates microtubule dynamics in Sertoli cells, a process that is essential for spermiogenesis and male fertility. Severs microtubules in an ATP-dependent manner, promoting rapid reorganization of cellular microtubule arrays.
messages: centrosome
messages: cytoskeleton
messages: spindle
messages: spindle pole

219594:RIC3
gene id: 219594:RIC3
uniprot id: A0A6J3D689
uniprot id: A0A6J3D747
names: Similarity
messages: Belongs to the ric-3 family.

219594:TMEM231
gene id: 219594:TMEM231
uniprot id: A0A6J3DPK3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM231 family.
messages: Membrane
messages: Transmembrane component of the tectonic-like complex, a complex localized at the transition zone of primary cilia and acting as a barrier that prevents diffusion of transmembrane proteins between the cilia and plasma membranes. Required for ciliogenesis and sonic hedgehog/SHH signaling.
messages: cilium membrane

219594:TMEM161B
gene id: 219594:TMEM161B
uniprot id: A0A6J3EGJ9
uniprot id: A0A6J3EKB2
uniprot id: A0A6J3ELU2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM161 family.
messages: Membrane

219594:FUCA1
gene id: 219594:FUCA1
uniprot id: A0A6J3E580
uniprot id: A0A6J3EA80
names: Function
names: Similarity
names: Subunit
messages: Alpha-L-fucosidase is responsible for hydrolyzing the alpha-1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins.
messages: Belongs to the glycosyl hydrolase 29 family.
messages: Homotetramer.

219594:LOC116486644
gene id: 219594:LOC116486644
uniprot id: A0A6J3CNJ2
names: Similarity
names: Subunit
messages: Belongs to the avian keratin family.
messages: The avian keratins (F-ker, S-ker, C-ker and B-ker) are a complex mixture of very similar polypeptides.

219594:GAREM2
gene id: 219594:GAREM2
uniprot id: A0A6J3CQ23
names: Similarity
messages: Belongs to the GAREM family.

219594:MITF
gene id: 219594:MITF
uniprot id: A0A6J3DFR3
uniprot id: A0A6J3DIE8
uniprot id: A0A6J3DJQ0
uniprot id: A0A6J3DLB3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MiT/TFE family.
messages: Nucleus

219594:AKAP8L
gene id: 219594:AKAP8L
uniprot id: A0A6J3ECG4
uniprot id: A0A6J3EG52
uniprot id: A0A6J3EHS2
names: Similarity
messages: Belongs to the AKAP95 family.

219594:EGF
gene id: 219594:EGF
uniprot id: A0A6J3CSB3
uniprot id: A0A6J3CUL6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:SLC35C2
gene id: 219594:SLC35C2
uniprot id: A0A6J3DU48
names: Subcellular Location Annotation
messages: Membrane

219594:ATP8B2
gene id: 219594:ATP8B2
uniprot id: A0A6J3EBC3
uniprot id: A0A6J3EEN2
uniprot id: A0A6J3EGP1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.
messages: Membrane

219594:NFU1
gene id: 219594:NFU1
uniprot id: A0A6J3E8L2
names: Similarity
messages: Belongs to the NifU family.

219594:CXXC5
gene id: 219594:CXXC5
uniprot id: A0A6J3DN97
names: Subcellular Location Annotation
messages: Cytoplasm

219594:TAFA4
gene id: 219594:TAFA4
uniprot id: A0A6J3DJ94
names: Similarity
messages: Belongs to the TAFA family.

219594:TRAM2
gene id: 219594:TRAM2
uniprot id: A0A6J3CSB4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAM family.
messages: Membrane

219594:STOML2
gene id: 219594:STOML2
uniprot id: A0A6J3EK37
names: Similarity
messages: Belongs to the band 7/mec-2 family.

219594:APOB
gene id: 219594:APOB
uniprot id: A0A6J3CVV9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:LOC116486272
gene id: 219594:LOC116486272
uniprot id: A0A6J3CJM4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.
messages: May play a role in lipid transport protein in Schwann cells. May bind cholesterol.
messages: Monomer.

219594:RIPOR2
gene id: 219594:RIPOR2
uniprot id: A0A6J3CJY7
uniprot id: A0A6J3CLM9
names: Similarity
messages: Belongs to the RIPOR family.

219594:C1H2orf49
gene id: 219594:C1H2orf49
uniprot id: A0A6J3E844
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ashwin family.
messages: Nucleus

219594:LOC116492172
gene id: 219594:LOC116492172
uniprot id: A0A6J3DEM7
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:LOC116499991
gene id: 219594:LOC116499991
uniprot id: A0A6J3EHD0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TGF-beta family.
messages: Homodimeric or heterodimeric through association with alpha and beta subunits, linked by one or more disulfide bonds. Inhibins are heterodimers of one alpha and one beta subunit. Activins are homo- or heterodimers of beta subunits only.
messages: Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition. Inhibins appear to oppose the functions of activins.
messages: Secreted

219594:CCDC34
gene id: 219594:CCDC34
uniprot id: A0A6J3D713
names: Subcellular Location Annotation
messages: flagellum

219594:CERT1
gene id: 219594:CERT1
uniprot id: A0A6J3EDL7
uniprot id: A0A6J3EH33
names: Subcellular Location Annotation
messages: Endoplasmic reticulum
messages: Golgi apparatus

219594:LOC116487105
gene id: 219594:LOC116487105
uniprot id: A0A6J3CMC8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cullin family.
messages: Cytoplasm

219594:SH3BP4
gene id: 219594:SH3BP4
uniprot id: A0A6J3DAA8
names: Subcellular Location Annotation
messages: Nucleus
messages: Vesicle
messages: clathrin-coated pit
messages: clathrin-coated vesicle

219594:NT5E
gene id: 219594:NT5E
uniprot id: A0A6J3CLB9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 5'-nucleotidase family.
messages: Membrane

219594:EMC1
gene id: 219594:EMC1
uniprot id: A0A6J3E1F0
uniprot id: A0A6J3E5N9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EMC1 family.
messages: Component of the ER membrane protein complex (EMC).
messages: Endoplasmic reticulum membrane
messages: Membrane

219594:NIPSNAP3A
gene id: 219594:NIPSNAP3A
uniprot id: A0A6J3EKB3
names: Similarity
messages: Belongs to the NipSnap family.

219594:LOC116496551
gene id: 219594:LOC116496551
uniprot id: A0A6J3E164
names: Subcellular Location Annotation
messages: Membrane

219594:TRIT1
gene id: 219594:TRIT1
uniprot id: A0A6J3E913
names: Function
names: Similarity
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37.

219594:TGIF2
gene id: 219594:TGIF2
uniprot id: A0A6J3DUA0
names: Subcellular Location Annotation
messages: Nucleus

219594:SYNPR
gene id: 219594:SYNPR
uniprot id: A0A6J3DJU1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptophysin/synaptobrevin family.
messages: Membrane

219594:GTPBP4
gene id: 219594:GTPBP4
uniprot id: A0A6J3CJZ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. NOG subfamily.
messages: Involved in the biogenesis of the 60S ribosomal subunit.
messages: nucleolus

219594:LOC116499273
gene id: 219594:LOC116499273
uniprot id: A0A6J3ECR1
names: Similarity
messages: Belongs to the actin family.

219594:PPDPFL
gene id: 219594:PPDPFL
uniprot id: A0A6J3CJE1
names: Similarity
messages: Belongs to the PPDPF family.

219594:LOC116499722
gene id: 219594:LOC116499722
uniprot id: A0A6J3EE75
names: Similarity
names: Subunit
messages: Belongs to the avian keratin family.
messages: The avian keratins (F-ker, S-ker, C-ker and B-ker) are a complex mixture of very similar polypeptides.

219594:USP43
gene id: 219594:USP43
uniprot id: A0A6J3DYI7
names: Similarity
messages: Belongs to the peptidase C19 family.

219594:LOC116499997
gene id: 219594:LOC116499997
uniprot id: A0A6J3EAQ8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TGF-beta family.
messages: Homodimeric or heterodimeric through association with alpha and beta subunits, linked by one or more disulfide bonds. Inhibins are heterodimers of one alpha and one beta subunit. Activins are homo- or heterodimers of beta subunits only.
messages: Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition. Inhibins appear to oppose the functions of activins.
messages: Secreted

219594:UBE2M
gene id: 219594:UBE2M
uniprot id: A0A6J3EG12
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

219594:TMEM63A
gene id: 219594:TMEM63A
uniprot id: A0A6J3CUC1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CSC1 (TC 1.A.17) family.
messages: Membrane

219594:LMF1
gene id: 219594:LMF1
uniprot id: A0A6J3DWQ8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lipase maturation factor family.
messages: Endoplasmic reticulum membrane
messages: Involved in the maturation of specific proteins in the endoplasmic reticulum.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

219594:LOC116502215
gene id: 219594:LOC116502215
uniprot id: A0A6J3ER88
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPOT14 family.
messages: Cytoplasm
messages: Nucleus

219594:MMACHC
gene id: 219594:MMACHC
uniprot id: A0A6J3DEH7
names: Similarity
messages: Belongs to the MMACHC family.

219594:TMEM200A
gene id: 219594:TMEM200A
uniprot id: A0A6J3CQ52
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM200 family.
messages: Membrane

219594:PLPP4
gene id: 219594:PLPP4
uniprot id: A0A6J3D877
uniprot id: A0A6J3DBR3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PA-phosphatase related phosphoesterase family.
messages: Membrane

219594:SEMA6A
gene id: 219594:SEMA6A
uniprot id: A0A6J3EE41
uniprot id: A0A6J3EFJ5
uniprot id: A0A6J3EJ26
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:NARF
gene id: 219594:NARF
uniprot id: A0A6J3DXD8
names: Similarity
messages: Belongs to the NARF family.

219594:CAPRIN2
gene id: 219594:CAPRIN2
uniprot id: A0A6J3D131
uniprot id: A0A6J3D3G1
uniprot id: A0A6J3D3Q3
uniprot id: A0A6J3D6Y9
names: Similarity
messages: Belongs to the caprin family.

219594:SRF
gene id: 219594:SRF
uniprot id: A0A6J3CR38
names: Subcellular Location Annotation
messages: Nucleus

219594:MC4R
gene id: 219594:MC4R
uniprot id: A0A6J3CJS5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Receptor specific to the heptapeptide core common to adrenocorticotropic hormone and alpha-, beta-, and gamma-MSH. Plays a central role in energy homeostasis and somatic growth. This receptor is mediated by G proteins that stimulate adenylate cyclase (cAMP).

219594:AGK
gene id: 219594:AGK
uniprot id: A0A6J3CTG8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AGK family.
messages: Membrane
messages: Mitochondrion inner membrane
messages: Mitochondrion intermembrane space

219594:ALDH5A1
gene id: 219594:ALDH5A1
uniprot id: A0A6J3CII0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the aldehyde dehydrogenase family.
messages: Catalyzes one step in the degradation of the inhibitory neurotransmitter gamma-aminobutyric acid (GABA).
messages: Homotetramer.
messages: Mitochondrion

219594:EME2
gene id: 219594:EME2
uniprot id: A0A6J3DUP1
names: Similarity
messages: Belongs to the EME1/MMS4 family.

219594:UTP11
gene id: 219594:UTP11
uniprot id: A0A6J3E9L6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UTP11 family.
messages: Component of the ribosomal small subunit (SSU) processome.
messages: Involved in nucleolar processing of pre-18S ribosomal RNA.
messages: nucleolus

219594:FAM83F
gene id: 219594:FAM83F
uniprot id: A0A6J3EL22
names: Similarity
messages: Belongs to the FAM83 family.

219594:GGPS1
gene id: 219594:GGPS1
uniprot id: A0A6J3CPG0
uniprot id: A0A6J3CRR1
uniprot id: A0A6J3CSS0
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

219594:RPS23
gene id: 219594:RPS23
uniprot id: A0A6J3EK79
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Rough endoplasmic reticulum

219594:TIMM22
gene id: 219594:TIMM22
uniprot id: A0A6J3E0T8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Tim17/Tim22/Tim23 family.
messages: Component of the TIM22 complex.
messages: Essential core component of the TIM22 complex, a complex that mediates the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane. In the TIM22 complex, it constitutes the voltage-activated and signal-gated channel. Forms a twin-pore translocase that uses the membrane potential as external driving force in 2 voltage-dependent steps.
messages: Membrane
messages: Mitochondrion inner membrane

219594:LOC116485948
gene id: 219594:LOC116485948
uniprot id: A0A6J3CJU3
names: Subcellular Location Annotation
messages: Membrane

219594:YWHAH
gene id: 219594:YWHAH
uniprot id: A0A6J3DXN6
names: Similarity
messages: Belongs to the 14-3-3 family.

219594:HUS1
gene id: 219594:HUS1
uniprot id: A0A6J3CMC2
names: Similarity
messages: Belongs to the HUS1 family.

219594:LOC116490068
gene id: 219594:LOC116490068
uniprot id: A0A6J3D0L8
uniprot id: A0A6J3D397
names: Similarity
messages: Belongs to the serpin family.

219594:LOC116488810
gene id: 219594:LOC116488810
uniprot id: A0A6J3CWU1
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

219594:LOC116495420
gene id: 219594:LOC116495420
uniprot id: A0A6J3DQK3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the globin family.
messages: Heterotetramer of two alpha-D chains and two beta chains.
messages: Involved in oxygen transport from the lung to the various peripheral tissues.

219594:FOXO3
gene id: 219594:FOXO3
uniprot id: A0A6J3CWV6
names: Subcellular Location Annotation
messages: Nucleus

219594:ZADH2
gene id: 219594:ZADH2
uniprot id: A0A6J3CHD8
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily.

219594:LAMP1
gene id: 219594:LAMP1
uniprot id: A0A6J3E739
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LAMP family.
messages: Endosome membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Lysosome membrane
messages: Membrane

219594:MTAP
gene id: 219594:MTAP
uniprot id: A0A6J3EK98
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily.
messages: Catalyzes the reversible phosphorylation of S-methyl-5'-thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates.
messages: Cytoplasm
messages: Homotrimer.
messages: Nucleus

219594:INTS14
gene id: 219594:INTS14
uniprot id: A0A6J3DIZ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the INTS14 family.
messages: Nucleus
messages: Probable component of the Integrator (INT) complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'-box-dependent processing.

219594:TNFRSF25
gene id: 219594:TNFRSF25
uniprot id: A0A6J3E601
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:LOC116485699
gene id: 219594:LOC116485699
uniprot id: A0A6J3CI43
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c family.
messages: Binds 1 heme c group covalently per subunit.
messages: Membrane
messages: Mitochondrion inner membrane

219594:ARHGEF7
gene id: 219594:ARHGEF7
uniprot id: A0A6J3EIZ5
uniprot id: A0A6J3EP91
uniprot id: A0A6J3EQN7
names: Subcellular Location Annotation
messages: lamellipodium

219594:TCEANC2
gene id: 219594:TCEANC2
uniprot id: A0A6J3DB21
names: Subcellular Location Annotation
messages: Nucleus

219594:LOC116492438
gene id: 219594:LOC116492438
uniprot id: A0A6J3DCB9
names: Similarity
messages: Belongs to the CD200R family.

219594:SELENOF
gene id: 219594:SELENOF
uniprot id: A0A6J3DFG7
names: Similarity
messages: Belongs to the selenoprotein M/F family.

219594:ATP2A3
gene id: 219594:ATP2A3
uniprot id: A0A6J3DYS5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIA subfamily.
messages: Catalyzes the hydrolysis of ATP coupled with the transport of calcium.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Sarcoplasmic reticulum membrane

219594:TMEM8B
gene id: 219594:TMEM8B
uniprot id: A0A6J3EHF4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM8 family.
messages: Cell membrane
messages: Membrane

219594:HADHB
gene id: 219594:HADHB
uniprot id: A0A6J3CWN2
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

219594:SLC46A3
gene id: 219594:SLC46A3
uniprot id: A0A6J3ELB5
names: Subcellular Location Annotation
messages: Membrane

219594:UROS
gene id: 219594:UROS
uniprot id: A0A6J3DD79
names: Similarity
messages: Belongs to the uroporphyrinogen-III synthase family.

219594:F5
gene id: 219594:F5
uniprot id: A0A6J3DIR4
names: Similarity
messages: Belongs to the multicopper oxidase family.

219594:RMI1
gene id: 219594:RMI1
uniprot id: A0A6J3EH48
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RMI1 family.
messages: Essential component of the RMI complex, a complex that plays an important role in the processing of homologous recombination intermediates to limit DNA crossover formation in cells. Promotes TOP3A binding to double Holliday junctions (DHJ) and hence stimulates TOP3A-mediated dissolution. Required for BLM phosphorylation during mitosis. Within the BLM complex, required for BLM and TOP3A stability.
messages: Nucleus

219594:MED23
gene id: 219594:MED23
uniprot id: A0A6J3CMC1
uniprot id: A0A6J3CP60
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Mediator complex subunit 23 family.
messages: Nucleus

219594:ZNF277
gene id: 219594:ZNF277
uniprot id: A0A6J3EET1
names: Similarity
messages: Belongs to the ZNF277 family.

219594:RBL1
gene id: 219594:RBL1
uniprot id: A0A6J3DSC1
uniprot id: A0A6J3DUF4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the retinoblastoma protein (RB) family.
messages: Nucleus

219594:ABCB10
gene id: 219594:ABCB10
uniprot id: A0A6J3CL81
names: Subcellular Location Annotation
messages: Membrane

219594:CRPPA
gene id: 219594:CRPPA
uniprot id: A0A6J3CEP1
uniprot id: A0A6J3CFP1
uniprot id: A0A6J3CJA8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Homodimer.
messages: cytosol

219594:ORC1
gene id: 219594:ORC1
uniprot id: A0A6J3DB39
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ORC1 family.
messages: Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication.
messages: Nucleus
messages: ORC is composed of six subunits.

219594:PDE6D
gene id: 219594:PDE6D
uniprot id: A0A6J3DIK3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PDE6D/unc-119 family.
messages: Cytoplasmic vesicle membrane
messages: Interacts with the prenylated catalytic subunits of PDE6, an oligomer composed of two catalytic chains and two inhibitory chains; has no effect on enzyme activity but promotes the release of the prenylated enzyme from cell membrane.
messages: Promotes the release of prenylated target proteins from cellular membranes. Modulates the activity of prenylated or palmitoylated Ras family members by regulating their subcellular location. Required for normal ciliary targeting of farnesylated target proteins, such as INPP5E. Modulates the subcellular location of target proteins by acting as a GTP specific dissociation inhibitor (GDI). Increases the affinity of ARL3 for GTP by several orders of magnitude. Stabilizes ARL3-GTP by decreasing the nucleotide dissociation rate.
messages: cilium basal body
messages: cytosol

219594:LOC116490394
gene id: 219594:LOC116490394
uniprot id: A0A6J3D4L9
uniprot id: A0A6J3D505
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
messages: Membrane

219594:AP3S1
gene id: 219594:AP3S1
uniprot id: A0A6J3EDV9
uniprot id: A0A6J3EFA8
uniprot id: A0A6J3EIQ7
uniprot id: A0A6J3EKN1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adaptor complexes small subunit family.
messages: Cytoplasmic vesicle membrane
messages: Membrane
messages: Part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane and may be directly involved in trafficking to lysosomes. In concert with the BLOC-1 complex, AP-3 is required to target cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals.

219594:PCID2
gene id: 219594:PCID2
uniprot id: A0A6J3EHM6
names: Similarity
messages: Belongs to the CSN12 family.

219594:LOC116499890
gene id: 219594:LOC116499890
uniprot id: A0A6J3EAB0
names: Similarity
messages: Belongs to the intermediate filament family.

219594:LOC116498264
gene id: 219594:LOC116498264
uniprot id: A0A6J3E433
names: Cofactor
names: PTM
names: Similarity
messages: Belongs to the copper/topaquinone oxidase family.
messages: Contains 1 topaquinone per subunit.
messages: Topaquinone (TPQ) is generated by copper-dependent autoxidation of a specific tyrosyl residue.

219594:ST6GALNAC2
gene id: 219594:ST6GALNAC2
uniprot id: A0A6J3DVU6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

219594:TMEM70
gene id: 219594:TMEM70
uniprot id: A0A6J3CJU8
names: Similarity
messages: Belongs to the TMEM70 family.

219594:FOXI2
gene id: 219594:FOXI2
uniprot id: A0A6J3DCC3
names: Subcellular Location Annotation
messages: Nucleus

219594:TAF15
gene id: 219594:TAF15
uniprot id: A0A6J3E4G0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRM TET family.
messages: Nucleus

219594:A4GNT
gene id: 219594:A4GNT
uniprot id: A0A6J3DCX2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 32 family.
messages: Golgi apparatus membrane

219594:RGS2
gene id: 219594:RGS2
uniprot id: A0A6J3DC64
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: nucleolus

219594:LOC116501882
gene id: 219594:LOC116501882
uniprot id: A0A6J3ENC5
names: Similarity
messages: Belongs to the CRISP family.

219594:EP300
gene id: 219594:EP300
uniprot id: A0A6J3CRF0
names: Subcellular Location Annotation
messages: Cytoplasm

219594:TJP1
gene id: 219594:TJP1
uniprot id: A0A6J3DH02
uniprot id: A0A6J3DJM7
uniprot id: A0A6J3DJN2
uniprot id: A0A6J3DL37
uniprot id: A0A6J3DMJ2
uniprot id: A0A6J3DN41
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: tight junction

219594:RNH1
gene id: 219594:RNH1
uniprot id: A0A6J3D410
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Forms high-affinity heterodimers with RNASE1, ANG and RNASE2.
messages: Ribonuclease inhibitor which inhibits RNASE1, RNASE2 and ANG. May play a role in redox homeostasis.

219594:DPH6
gene id: 219594:DPH6
uniprot id: A0A6J3D0S9
uniprot id: A0A6J3D6M3
names: Similarity
messages: Belongs to the Diphthine--ammonia ligase family.

219594:TMEM80
gene id: 219594:TMEM80
uniprot id: A0A6J3D4G2
uniprot id: A0A6J3D4U4
names: Subcellular Location Annotation
messages: Membrane

219594:NOP56
gene id: 219594:NOP56
uniprot id: A0A6J3CUS8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NOP5/NOP56 family.
messages: nucleolus

219594:LOC116500329
gene id: 219594:LOC116500329
uniprot id: A0A6J3ED46
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

219594:PTHLH
gene id: 219594:PTHLH
uniprot id: A0A6J3E3R2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the parathyroid hormone family.
messages: Secreted

219594:UBE4A
gene id: 219594:UBE4A
uniprot id: A0A6J3E3L3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ubiquitin conjugation factor E4 family.
messages: Cytoplasm

219594:PHKA2
gene id: 219594:PHKA2
uniprot id: A0A6J3EAZ6
uniprot id: A0A6J3EB08
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Although the final Cys may be farnesylated, the terminal tripeptide is probably not removed, and the C-terminus is not methylated.
messages: Belongs to the phosphorylase b kinase regulatory chain family.
messages: Cell membrane
messages: Membrane
messages: Phosphorylase b kinase catalyzes the phosphorylation of serine in certain substrates, including troponin I. The alpha chain may bind calmodulin.

219594:SLC25A20
gene id: 219594:SLC25A20
uniprot id: A0A6J3DLE9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

219594:DIS3L
gene id: 219594:DIS3L
uniprot id: A0A6J3DMZ8
uniprot id: A0A6J3DNM0
names: Similarity
messages: Belongs to the RNR ribonuclease family.

219594:LOC116485620
gene id: 219594:LOC116485620
uniprot id: A0A6J3CHV7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

219594:SUFU
gene id: 219594:SUFU
uniprot id: A0A6J3D732
uniprot id: A0A6J3DAG2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SUFU family.
messages: Cytoplasm
messages: Nucleus

219594:CDC5L
gene id: 219594:CDC5L
uniprot id: A0A6J3CVM2
names: Similarity
messages: Belongs to the CEF1 family.

219594:ADGRA2
gene id: 219594:ADGRA2
uniprot id: A0A6J3ECX9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 2 family. Adhesion G-protein coupled receptor (ADGR) subfamily.
messages: Membrane

219594:PDIK1L
gene id: 219594:PDIK1L
uniprot id: A0A6J3EA86
names: Similarity
messages: Belongs to the protein kinase superfamily.

219594:ITGA3
gene id: 219594:ITGA3
uniprot id: A0A6J3EA85
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin alpha chain family.
messages: Membrane

219594:KPNB1
gene id: 219594:KPNB1
uniprot id: A0A6J3E9I8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the importin beta family. Importin beta-1 subfamily.
messages: Cytoplasm

219594:BNIP3L
gene id: 219594:BNIP3L
uniprot id: A0A6J3EF61
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NIP3 family.
messages: Membrane

219594:SERPINB5
gene id: 219594:SERPINB5
uniprot id: A0A6J3CHK6
names: Similarity
messages: Belongs to the serpin family. Ov-serpin subfamily.

219594:LOC116487635
gene id: 219594:LOC116487635
uniprot id: A0A6J3CR52
names: Similarity
messages: Belongs to the HEBP family.

219594:PIANP
gene id: 219594:PIANP
uniprot id: A0A6J3DT26
names: Subcellular Location Annotation
messages: Membrane

219594:BTC
gene id: 219594:BTC
uniprot id: A0A6J3CW36
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:UTP23
gene id: 219594:UTP23
uniprot id: A0A6J3CI18
names: Subcellular Location Annotation
messages: nucleolus

219594:LOC116500951
gene id: 219594:LOC116500951
uniprot id: A0A6J3EG50
names: Similarity
messages: Belongs to the TPPP family.

219594:LOC116498279
gene id: 219594:LOC116498279
uniprot id: A0A6J3E8H9
names: Similarity
messages: Belongs to the intermediate filament family.

219594:FEZ2
gene id: 219594:FEZ2
uniprot id: A0A6J3CN41
uniprot id: A0A6J3CU64
names: Similarity
messages: Belongs to the zygin family.

219594:SOST
gene id: 219594:SOST
uniprot id: A0A6J3E9B5
names: Caution
names: Similarity
messages: Belongs to the sclerostin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:DENND5A
gene id: 219594:DENND5A
uniprot id: A0A6J3CWW9
uniprot id: A0A6J3CZG0
uniprot id: A0A6J3D1Q4
uniprot id: A0A6J3D2V0
names: Caution
names: Similarity
messages: Belongs to the RAB6IP1 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:LOC116500750
gene id: 219594:LOC116500750
uniprot id: A0A6J3EDQ4
uniprot id: A0A6J3EIY7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit. The potassium ion interacts primarily with the substrate.
messages: Binds 2 magnesium ions per subunit. The magnesium ions interact primarily with the substrate.
messages: Catalyzes the formation of S-adenosylmethionine from methionine and ATP.

219594:LOC116494418
gene id: 219594:LOC116494418
uniprot id: A0A6J3DQC9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inositol 1,4,5-trisphosphate 5-phosphatase family.
messages: Membrane

219594:STARD3
gene id: 219594:STARD3
uniprot id: A0A6J3E5B8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STARD3 family.
messages: Endosome membrane
messages: Late endosome membrane
messages: Membrane

219594:LOC116497625
gene id: 219594:LOC116497625
uniprot id: A0A6J3E7G9
names: Subcellular Location Annotation
messages: Membrane

219594:HDAC1
gene id: 219594:HDAC1
uniprot id: A0A6J3E8U6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone deacetylase family. HD Type 1 subfamily.
messages: Nucleus

219594:LOC116498258
gene id: 219594:LOC116498258
uniprot id: A0A6J3E8G0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the COQ10 family.
messages: Interacts with coenzyme Q.
messages: Required for the function of coenzyme Q in the respiratory chain. May serve as a chaperone or may be involved in the transport of Q6 from its site of synthesis to the catalytic sites of the respiratory complexes.

219594:SMARCB1
gene id: 219594:SMARCB1
uniprot id: A0A6J3DY53
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SNF5 family.
messages: Component of the multiprotein chromatin-remodeling complexes SWI/SNF.
messages: Nucleus

219594:CDCA2
gene id: 219594:CDCA2
uniprot id: A0A6J3E8Q1
uniprot id: A0A6J3EA68
names: Subcellular Location Annotation
messages: Nucleus

219594:DNAH10
gene id: 219594:DNAH10
uniprot id: A0A6J3E092
names: Similarity
messages: Belongs to the dynein heavy chain family.

219594:DCLK1
gene id: 219594:DCLK1
uniprot id: A0A6J3D0H6
uniprot id: A0A6J3D2X9
uniprot id: A0A6J3D380
names: Similarity
messages: Belongs to the protein kinase superfamily.
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. CaMK subfamily.

219594:LOC116495607
gene id: 219594:LOC116495607
uniprot id: A0A6J3DXU4
names: Subcellular Location Annotation
messages: Golgi apparatus membrane
messages: Membrane

219594:LOC116497518
gene id: 219594:LOC116497518
uniprot id: A0A6J3E248
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

219594:LOC116492513
gene id: 219594:LOC116492513
uniprot id: A0A6J3DF63
names: Similarity
messages: Belongs to the cytochrome P450 family.

219594:CUX1
gene id: 219594:CUX1
uniprot id: A0A6J3DZC0
uniprot id: A0A6J3E0X0
uniprot id: A0A6J3E4E6
uniprot id: A0A6J3E4F5
uniprot id: A0A6J3E5F2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CASP family.
messages: Belongs to the CUT homeobox family.
messages: Golgi apparatus membrane
messages: Membrane
messages: Nucleus

219594:ZC3H12C
gene id: 219594:ZC3H12C
uniprot id: A0A6J3EQK8
names: Similarity
messages: Belongs to the ZC3H12 family.

219594:AGRN
gene id: 219594:AGRN
uniprot id: A0A6J3E1C3
uniprot id: A0A6J3E1C7
uniprot id: A0A6J3E2Q3
uniprot id: A0A6J3E5L3
uniprot id: A0A6J3E7J4
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

219594:GPR137B
gene id: 219594:GPR137B
uniprot id: A0A6J3CNE9
names: Subcellular Location Annotation
messages: Lysosome membrane
messages: Membrane

219594:HAP1
gene id: 219594:HAP1
uniprot id: A0A6J3E5K1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the milton family.
messages: Early endosome
messages: Mitochondrion

219594:LOC116498548
gene id: 219594:LOC116498548
uniprot id: A0A6J3E9I9
names: Similarity
messages: Belongs to the intermediate filament family.

219594:TMA16
gene id: 219594:TMA16
uniprot id: A0A6J3CX89
names: Function
names: Similarity
names: Subunit
messages: Associates with pre-60S ribosomal particles.
messages: Belongs to the TMA16 family.
messages: Involved in the biogenesis of the 60S ribosomal subunit in the nucleus.

219594:TRMT11
gene id: 219594:TRMT11
uniprot id: A0A6J3CRA4
uniprot id: A0A6J3CTL0
names: Function
messages: Catalytic subunit of an S-adenosyl-L-methionine-dependent tRNA methyltransferase complex that mediates the methylation of the guanosine nucleotide at position 10 (m2G10) in tRNAs.

219594:LOC116499714
gene id: 219594:LOC116499714
uniprot id: A0A6J3EB67
names: Similarity
messages: Belongs to the protein kinase superfamily.

219594:CLK3
gene id: 219594:CLK3
uniprot id: A0A6J3DL25
names: Similarity
messages: Belongs to the protein kinase superfamily.

219594:OSBP
gene id: 219594:OSBP
uniprot id: A0A6J3D2L6
names: Similarity
messages: Belongs to the OSBP family.

219594:HOXC4
gene id: 219594:HOXC4
uniprot id: A0A6J3EFM8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Antp homeobox family.
messages: Nucleus

219594:LOC116494133
gene id: 219594:LOC116494133
uniprot id: A0A6J3DQA9
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

219594:LOC116495736
gene id: 219594:LOC116495736
uniprot id: A0A6J3DXC3
names: Similarity
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.

219594:DLX2
gene id: 219594:DLX2
uniprot id: A0A6J3D9D6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the distal-less homeobox family.
messages: Nucleus

219594:LOC116501388
gene id: 219594:LOC116501388
uniprot id: A0A6J3ELQ7
names: Function
messages: The products of the Gag polyproteins of infectious retroviruses perform highly complex orchestrated tasks during the assembly, budding, maturation, and infection stages of the viral replication cycle. During viral assembly, the proteins form membrane associations and self-associations that ultimately result in budding of an immature virion from the infected cell. Gag precursors also function during viral assembly to selectively bind and package two plus strands of genomic RNA. Endogenous Gag proteins may have kept, lost or modified their original function during evolution.

219594:LOC116487662
gene id: 219594:LOC116487662
uniprot id: A0A6J3CUQ5
names: Similarity
messages: Belongs to the cytochrome P450 family.

219594:LOC116494617
gene id: 219594:LOC116494617
uniprot id: A0A6J3DS40
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nonaspanin (TM9SF) (TC 9.A.2) family.
messages: Membrane

219594:LOC116485943
gene id: 219594:LOC116485943
uniprot id: A0A6J3CGX1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor.

219594:CSF1R
gene id: 219594:CSF1R
uniprot id: A0A6J3DTB2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.
messages: Cell membrane
messages: Membrane

219594:STK4
gene id: 219594:STK4
uniprot id: A0A6J3DS03
uniprot id: A0A6J3DX43
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.
messages: Nucleus

219594:CA7
gene id: 219594:CA7
uniprot id: A0A6J3DJT1
uniprot id: A0A6J3DP16
names: Function
names: Similarity
messages: Belongs to the alpha-carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

219594:TSPAN2
gene id: 219594:TSPAN2
uniprot id: A0A6J3E736
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

219594:LPIN3
gene id: 219594:LPIN3
uniprot id: A0A6J3DUM4
names: Similarity
messages: Belongs to the lipin family.

219594:TMEM33
gene id: 219594:TMEM33
uniprot id: A0A6J3CVS8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PER33/POM33 family.
messages: Membrane

219594:MCEE
gene id: 219594:MCEE
uniprot id: A0A6J3DGV1
uniprot id: A0A6J3DMD4
names: Similarity
messages: Belongs to the methylmalonyl-CoA epimerase family.

219594:LOC116492020
gene id: 219594:LOC116492020
uniprot id: A0A6J3DFX2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FMO family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Microsome membrane

219594:PSMF1
gene id: 219594:PSMF1
uniprot id: A0A6J3DZ22
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the proteasome inhibitor PI31 family.
messages: Cytoplasm
messages: Endoplasmic reticulum
messages: Plays an important role in control of proteasome function. Inhibits the hydrolysis of protein and peptide substrates by the 20S proteasome. Also inhibits the activation of the proteasome by the proteasome regulatory proteins PA700 and PA28.

219594:SLC1A4
gene id: 219594:SLC1A4
uniprot id: A0A6J3CM66
uniprot id: A0A6J3CN96
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Membrane

219594:HMCN2
gene id: 219594:HMCN2
uniprot id: A0A6J3E3F8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:RBM17
gene id: 219594:RBM17
uniprot id: A0A6J3DYZ6
uniprot id: A0A6J3DZ25
uniprot id: A0A6J3DZS5
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Associates with the spliceosome.
messages: Nucleus
messages: Splice factor that binds to the single-stranded 3'AG at the exon/intron border and promotes its utilization in the second catalytic step. Involved in the regulation of alternative splicing and the utilization of cryptic splice sites.

219594:UNC119B
gene id: 219594:UNC119B
uniprot id: A0A6J3DYU0
names: Similarity
messages: Belongs to the PDE6D/unc-119 family.

219594:NCBP3
gene id: 219594:NCBP3
uniprot id: A0A6J3DZW7
uniprot id: A0A6J3E437
names: Similarity
messages: Belongs to the NCBP3 family.

219594:ARRDC4
gene id: 219594:ARRDC4
uniprot id: A0A6J3DK19
names: Similarity
messages: Belongs to the arrestin family.

219594:AGO2
gene id: 219594:AGO2
uniprot id: A0A6J3CIX7
uniprot id: A0A6J3CKD4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argonaute family. Ago subfamily.
messages: Component of the RISC loading complex (RLC), or micro-RNA (miRNA) loading complex (miRLC), which is composed of dicer1, ago2 and tarbp2. Note that the trimeric RLC/miRLC is also referred to as RISC.
messages: P-body
messages: Required for RNA-mediated gene silencing (RNAi) by the RNA-induced silencing complex (RISC). The 'minimal RISC' appears to include ago2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the mRNA specifically by ago2. Binding of RISC to a partially complementary mRNA results in silencing through inhibition of translation, and this is independent of endonuclease activity. The inhibition of translational initiation leads to the accumulation of the affected mRNA in cytoplasmic processing bodies (P-bodies), where mRNA degradation may subsequently occur.
messages: The Piwi domain may perform RNA cleavage by a mechanism similar to that of RNase H. However, while RNase H utilizes a triad of Asp-Asp-Glu (DDE) for metal ion coordination, this protein appears to utilize a triad of Asp-Asp-His (DDH).

219594:LOC116502368
gene id: 219594:LOC116502368
uniprot id: A0A6J3EK32
names: Similarity
names: Subunit
messages: Belongs to the histone H3 family.
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

219594:TTC21B
gene id: 219594:TTC21B
uniprot id: A0A6J3D5Q0
names: Similarity
messages: Belongs to the TTC21 family.

219594:TMEM43
gene id: 219594:TMEM43
uniprot id: A0A6J3DLI8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM43 family.
messages: Membrane

219594:PDE7A
gene id: 219594:PDE7A
uniprot id: A0A6J3CH23
uniprot id: A0A6J3CJ05
uniprot id: A0A6J3CKP4
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

219594:EPHA4
gene id: 219594:EPHA4
uniprot id: A0A6J3DGU5
names: Subcellular Location Annotation
messages: Early endosome
messages: Endosome
messages: Membrane

219594:MRPL15
gene id: 219594:MRPL15
uniprot id: A0A6J3CNR5
names: Similarity
messages: Belongs to the universal ribosomal protein uL15 family.

219594:UCK2
gene id: 219594:UCK2
uniprot id: A0A6J3DFB7
names: Similarity
messages: Belongs to the uridine kinase family.

219594:METAP2
gene id: 219594:METAP2
uniprot id: A0A6J3E259
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase eukaryotic type 2 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Binds EIF2S1 at low magnesium concentrations. Interacts strongly with the eIF-2 gamma-subunit EIF2S3.
messages: Contains approximately 12 O-linked N-acetylglucosamine (GlcNAc) residues. O-glycosylation is required for EIF2S1 binding.
messages: Cotranslationally removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val).
messages: Cytoplasm
messages: Protects eukaryotic initiation factor EIF2S1 from translation-inhibiting phosphorylation by inhibitory kinases such as EIF2AK2/PKR and EIF2AK1/HCR. Plays a critical role in the regulation of protein synthesis.

219594:ASPH
gene id: 219594:ASPH
uniprot id: A0A6J3CC22
uniprot id: A0A6J3CDQ0
uniprot id: A0A6J3CEP8
uniprot id: A0A6J3CEQ3
uniprot id: A0A6J3CGI6
uniprot id: A0A6J3CGJ2
uniprot id: A0A6J3CIC0
uniprot id: A0A6J3CIC5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartyl/asparaginyl beta-hydroxylase family.
messages: Membrane

219594:IRF2BPL
gene id: 219594:IRF2BPL
uniprot id: A0A6J3D1X3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IRF2BP family.
messages: Nucleus

219594:GFM1
gene id: 219594:GFM1
uniprot id: A0A6J3DI22
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTP-binding elongation factor family. EF-G/EF-2 subfamily.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mitochondrial GTPase that catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome. Does not mediate the disassembly of ribosomes from messenger RNA at the termination of mitochondrial protein biosynthesis.
messages: Mitochondrion
messages: Nucleus

219594:SLC6A1
gene id: 219594:SLC6A1
uniprot id: A0A6J3DE60
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

219594:GBX1
gene id: 219594:GBX1
uniprot id: A0A6J3CLB8
names: Subcellular Location Annotation
messages: Nucleus

219594:DGKZ
gene id: 219594:DGKZ
uniprot id: A0A6J3D758
names: Similarity
messages: Belongs to the eukaryotic diacylglycerol kinase family.

219594:ERAL1
gene id: 219594:ERAL1
uniprot id: A0A6J3E1R6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Membrane
messages: Mitochondrion inner membrane
messages: Probable GTPase that plays a role in the mitochondrial ribosomal small subunit assembly. Specifically binds the 12S mitochondrial rRNA (12S mt-rRNA) to a 33 nucleotide section delineating the 3' terminal stem-loop region. May act as a chaperone that protects the 12S mt-rRNA on the 28S mitoribosomal subunit during ribosomal small subunit assembly.

219594:LOC116499748
gene id: 219594:LOC116499748
uniprot id: A0A6J3EEK3
names: Similarity
names: Subunit
messages: Belongs to the avian keratin family.
messages: The avian keratins (F-ker, S-ker, C-ker and B-ker) are a complex mixture of very similar polypeptides.

219594:HTR2C
gene id: 219594:HTR2C
uniprot id: A0A6J3DRW6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

219594:NIM1K
gene id: 219594:NIM1K
uniprot id: A0A6J3EGL0
names: Similarity
messages: Belongs to the protein kinase superfamily.

219594:SMPDL3A
gene id: 219594:SMPDL3A
uniprot id: A0A6J3CPD4
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acid sphingomyelinase family.
messages: Binds 2 Zn(2+) per subunit.
messages: Secreted

219594:TACC2
gene id: 219594:TACC2
uniprot id: A0A6J3D8Q7
uniprot id: A0A6J3D994
uniprot id: A0A6J3DBF6
uniprot id: A0A6J3DBX4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACC family.
messages: Cytoplasm

219594:TAF7L
gene id: 219594:TAF7L
uniprot id: A0A6J3DPZ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAF7 family.
messages: Nucleus

219594:LOC116493649
gene id: 219594:LOC116493649
uniprot id: A0A6J3DKH8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDC42SE/SPEC family.
messages: Cell membrane
messages: Membrane
messages: cytoskeleton

219594:LOC116498529
gene id: 219594:LOC116498529
uniprot id: A0A6J3EBH6
names: Similarity
names: Subunit
messages: Belongs to the avian keratin family.
messages: The avian keratins (F-ker, S-ker, C-ker and B-ker) are a complex mixture of very similar polypeptides.

219594:SUV39H2
gene id: 219594:SUV39H2
uniprot id: A0A6J3EJS2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. Suvar3-9 subfamily.
messages: Nucleus
messages: centromere

219594:LRP1
gene id: 219594:LRP1
uniprot id: A0A6J3EAU0
uniprot id: A0A6J3EFW2
names: Caution
names: Similarity
messages: Belongs to the LDLR family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:ERMN
gene id: 219594:ERMN
uniprot id: A0A6J3D7Z8
names: Function
names: Subunit
messages: Binds actin.
messages: Plays a role in cytoskeletal rearrangements during the late wrapping and/or compaction phases of myelinogenesis as well as in maintenance and stability of myelin sheath in the adult. May play an important role in late-stage oligodendroglia maturation, myelin/Ranvier node formation during CNS development, and in the maintenance and plasticity of related structures in the mature CNS.

219594:CAMLG
gene id: 219594:CAMLG
uniprot id: A0A6J3DQD2
names: Function
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Required for the post-translational delivery of tail-anchored (TA) proteins to the endoplasmic reticulum. Together with GET1/WRB, acts as a membrane receptor for soluble GET3/TRC40, which recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. Required for the stability of GET1. Stimulates calcium signaling in T cells through its involvement in elevation of intracellular calcium. Essential for the survival of peripheral follicular B cells.

219594:HHEX
gene id: 219594:HHEX
uniprot id: A0A6J3D7K0
names: Subcellular Location Annotation
messages: Nucleus

219594:CDKAL1
gene id: 219594:CDKAL1
uniprot id: A0A6J3CIW1
uniprot id: A0A6J3CKJ8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methylthiotransferase family. CDKAL1 subfamily.
messages: Binds 1 or 2 [4Fe-4S] cluster. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-threonylcarbamoyladenosine (t(6)A), leading to the formation of 2-methylthio-N6-threonylcarbamoyladenosine (ms(2)t(6)A) at position 37 in tRNAs that read codons beginning with adenine.
messages: Endoplasmic reticulum membrane

219594:AMPD1
gene id: 219594:AMPD1
uniprot id: A0A6J3EBN6
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.

219594:LOC116493247
gene id: 219594:LOC116493247
uniprot id: A0A6J3DLX3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dynein light chain family.
messages: cytoskeleton

219594:PLCB4
gene id: 219594:PLCB4
uniprot id: A0A6J3CMD2
uniprot id: A0A6J3CSC3
uniprot id: A0A6J3CTF6
names: Cofactor
names: Function
messages: Binds 1 Ca(2+) ion per subunit.
messages: The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes.

219594:SDHAF2
gene id: 219594:SDHAF2
uniprot id: A0A6J3D3I6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SDHAF2 family.
messages: Interacts with SDHA within the SDH catalytic dimer.
messages: Mitochondrion matrix
messages: Plays an essential role in the assembly of succinate dehydrogenase (SDH), an enzyme complex (also referred to as respiratory complex II) that is a component of both the tricarboxylic acid (TCA) cycle and the mitochondrial electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SDHA of the SDH catalytic dimer.

219594:TMPO
gene id: 219594:TMPO
uniprot id: A0A6J3DTD4
uniprot id: A0A6J3DWD7
uniprot id: A0A6J3DWE7
uniprot id: A0A6J3DXC0
names: Similarity
messages: Belongs to the LEM family.

219594:LOC116502001
gene id: 219594:LOC116502001
uniprot id: A0A6J3EQC5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor T2R family.
messages: Membrane

219594:TH
gene id: 219594:TH
uniprot id: A0A6J3D6G5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the biopterin-dependent aromatic amino acid hydroxylase family.
messages: axon
messages: perinuclear region

219594:GOLM2
gene id: 219594:GOLM2
uniprot id: A0A6J3DJC0
uniprot id: A0A6J3DMS7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GOLM family.
messages: Membrane

219594:RPS27
gene id: 219594:RPS27
uniprot id: A0A6J3E9E1
names: Cofactor
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS27 family.
messages: Binds 1 zinc ion per subunit.

219594:FAM131A
gene id: 219594:FAM131A
uniprot id: A0A6J3DHT5
names: Similarity
messages: Belongs to the FAM131 family.

219594:MMP24
gene id: 219594:MMP24
uniprot id: A0A6J3DR91
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M10A family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Can bind about 5 Ca(2+) ions per subunit.

219594:HTT
gene id: 219594:HTT
uniprot id: A0A6J3CTU5
uniprot id: A0A6J3CZX3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the huntingtin family.
messages: Cytoplasm
messages: May play a role in microtubule-mediated transport or vesicle function.
messages: Nucleus

219594:ACVR1C
gene id: 219594:ACVR1C
uniprot id: A0A6J3D4A9
uniprot id: A0A6J3D6Z0
uniprot id: A0A6J3D7H3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
messages: Membrane

219594:AIG1
gene id: 219594:AIG1
uniprot id: A0A6J3CRP6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIG1 family.
messages: Membrane

219594:HS3ST2
gene id: 219594:HS3ST2
uniprot id: A0A6J3DVR6
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

219594:ANKRD34A
gene id: 219594:ANKRD34A
uniprot id: A0A6J3EGF5
names: Similarity
messages: Belongs to the ANKRD34 family.

219594:MSN
gene id: 219594:MSN
uniprot id: A0A6J3DKF8
names: Subcellular Location Annotation
messages: Membrane
messages: cytoskeleton

219594:SF3B4
gene id: 219594:SF3B4
uniprot id: A0A6J3EF60
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SF3B4 family.
messages: Nucleus

219594:HS6ST2
gene id: 219594:HS6ST2
uniprot id: A0A6J3DRB8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 6-O-sulfation enzyme which catalyzes the transfer of sulfate from 3'-phosphoadenosine 5'-phosphosulfate (PAPS) to position 6 of the N-sulfoglucosamine residue (GlcNS) of heparan sulfate.
messages: Belongs to the sulfotransferase 6 family.
messages: Membrane

219594:HIBCH
gene id: 219594:HIBCH
uniprot id: A0A6J3D5A7
uniprot id: A0A6J3D5L9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enoyl-CoA hydratase/isomerase family.
messages: Hydrolyzes 3-hydroxyisobutyryl-CoA (HIBYL-CoA), a saline catabolite. Has high activity toward isobutyryl-CoA. Could be an isobutyryl-CoA dehydrogenase that functions in valine catabolism. Also hydrolyzes 3-hydroxypropanoyl-CoA.
messages: Mitochondrion

219594:LOC116496596
gene id: 219594:LOC116496596
uniprot id: A0A6J3DWE1
uniprot id: A0A6J3E0K6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ubiA prenyltransferase family.
messages: Converts protoheme IX and farnesyl diphosphate to heme O.
messages: Membrane
messages: Mitochondrion membrane

219594:FIBIN
gene id: 219594:FIBIN
uniprot id: A0A6J3D4D0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FIBIN family.
messages: Endoplasmic reticulum
messages: Golgi apparatus
messages: Homodimer; disulfide-linked. Seems to also exist as monomers.
messages: Secreted

219594:CDK3
gene id: 219594:CDK3
uniprot id: A0A6J3DY55
names: Similarity
messages: Belongs to the protein kinase superfamily.

219594:LOC116492240
gene id: 219594:LOC116492240
uniprot id: A0A6J3DDX1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the spire family.
messages: Cell membrane
messages: Cytoplasmic vesicle membrane
messages: Membrane
messages: cytoskeleton

219594:CARMIL1
gene id: 219594:CARMIL1
uniprot id: A0A6J3CIM5
uniprot id: A0A6J3CK22
uniprot id: A0A6J3CK27
uniprot id: A0A6J3CLA8
uniprot id: A0A6J3CN81
uniprot id: A0A6J3CN88
uniprot id: A0A6J3CPM7
uniprot id: A0A6J3CPN1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CARMIL family.
messages: Cytoplasm

219594:LOC116490161
gene id: 219594:LOC116490161
uniprot id: A0A6J3D146
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

219594:CALHM3
gene id: 219594:CALHM3
uniprot id: A0A6J3DC94
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CALHM family.
messages: Membrane

219594:SERINC1
gene id: 219594:SERINC1
uniprot id: A0A6J3CT28
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TDE1 family.
messages: Membrane

219594:PDE8A
gene id: 219594:PDE8A
uniprot id: A0A6J3DGY9
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family. PDE8 subfamily.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

219594:FAM126A
gene id: 219594:FAM126A
uniprot id: A0A6J3CKN7
uniprot id: A0A6J3CP41
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Hyccin family.
messages: Cell membrane
messages: Membrane
messages: cytosol

219594:TFAP2D
gene id: 219594:TFAP2D
uniprot id: A0A6J3CTE5
names: Similarity
messages: Belongs to the AP-2 family.

219594:TMEM106B
gene id: 219594:TMEM106B
uniprot id: A0A6J3CGY4
names: Similarity
messages: Belongs to the TMEM106 family.

219594:MOCOS
gene id: 219594:MOCOS
uniprot id: A0A6J3CDC5
names: Function
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. MOCOS subfamily.
messages: Sulfurates the molybdenum cofactor. Sulfation of molybdenum is essential for xanthine dehydrogenase (XDH) and aldehyde oxidase (ADO) enzymes in which molybdenum cofactor is liganded by 1 oxygen and 1 sulfur atom in active form.

219594:EIF4G2
gene id: 219594:EIF4G2
uniprot id: A0A6J3CZI2
names: Similarity
messages: Belongs to the eukaryotic initiation factor 4G family.

219594:ELP2
gene id: 219594:ELP2
uniprot id: A0A6J3CGU9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat ELP2 family.
messages: Cytoplasm
messages: Nucleus

219594:GDI2
gene id: 219594:GDI2
uniprot id: A0A6J3DNL9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Rab GDI family.
messages: Cytoplasm
messages: Regulates the GDP/GTP exchange reaction of most RAB proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP.

219594:TMED10
gene id: 219594:TMED10
uniprot id: A0A6J3D176
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EMP24/GP25L family.
messages: Endoplasmic reticulum membrane
messages: Membrane

219594:GPBP1L1
gene id: 219594:GPBP1L1
uniprot id: A0A6J3DD63
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vasculin family.
messages: Nucleus

219594:VPS25
gene id: 219594:VPS25
uniprot id: A0A6J3E9S2
names: Similarity
messages: Belongs to the VPS25 family.

219594:PER2
gene id: 219594:PER2
uniprot id: A0A6J3DBW6
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

219594:ZC3H12A
gene id: 219594:ZC3H12A
uniprot id: A0A6J3E9A1
names: Similarity
messages: Belongs to the ZC3H12 family.

219594:LOC116500319
gene id: 219594:LOC116500319
uniprot id: A0A6J3ED34
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

219594:ISL2
gene id: 219594:ISL2
uniprot id: A0A6J3DJX2
names: Subcellular Location Annotation
messages: Nucleus

219594:PPP2CB
gene id: 219594:PPP2CB
uniprot id: A0A6J3CW12
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PPP phosphatase family.
messages: Cytoplasm

219594:KCNK10
gene id: 219594:KCNK10
uniprot id: A0A6J3D4P2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
messages: Membrane

219594:NKX1-1
gene id: 219594:NKX1-1
uniprot id: A0A6J3CUR3
names: Subcellular Location Annotation
messages: Nucleus

219594:EIF1
gene id: 219594:EIF1
uniprot id: A0A6J3E582
names: Similarity
messages: Belongs to the SUI1 family.

219594:PIK3C2A
gene id: 219594:PIK3C2A
uniprot id: A0A6J3CXW6
names: Similarity
messages: Belongs to the PI3/PI4-kinase family. Type III PI4K subfamily.

219594:TK2
gene id: 219594:TK2
uniprot id: A0A6J3DPN6
names: Similarity
messages: Belongs to the DCK/DGK family.

219594:NTMT1
gene id: 219594:NTMT1
uniprot id: A0A6J3DZF7
names: Similarity
messages: Belongs to the methyltransferase superfamily. NTM1 family.

219594:B4GALT1
gene id: 219594:B4GALT1
uniprot id: A0A6J3EBX2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 7 family.
messages: Golgi apparatus membrane
messages: Membrane
messages: Responsible for the synthesis of complex-type N-linked oligosaccharides in many glycoproteins as well as the carbohydrate moieties of glycolipids.

219594:FUBP1
gene id: 219594:FUBP1
uniprot id: A0A6J3DC15
uniprot id: A0A6J3DD01
uniprot id: A0A6J3DF25
uniprot id: A0A6J3DF30
uniprot id: A0A6J3DF75
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

219594:LOC116494859
gene id: 219594:LOC116494859
uniprot id: A0A6J3DQD5
uniprot id: A0A6J3DSE5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

219594:B3GALT5
gene id: 219594:B3GALT5
uniprot id: A0A6J3DZE5
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

219594:LOC116494491
gene id: 219594:LOC116494491
uniprot id: A0A6J3DRP9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Caudal homeobox family.
messages: Nucleus

219594:EZH1
gene id: 219594:EZH1
uniprot id: A0A6J3EA34
uniprot id: A0A6J3EBI7
names: Subcellular Location Annotation
messages: Nucleus

219594:INO80
gene id: 219594:INO80
uniprot id: A0A6J3D4Z2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATPase component of the INO80 complex which remodels chromatin by shifting nucleosomes and is involved in DNA repair.
messages: Belongs to the SNF2/RAD54 helicase family.
messages: Component of the INO80 chromatin-remodeling complex.
messages: Nucleus
messages: The DBINO region is involved in binding to DNA.

219594:LOC116501340
gene id: 219594:LOC116501340
uniprot id: A0A6J3ELK2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

219594:CKAP2
gene id: 219594:CKAP2
uniprot id: A0A6J3EJM7
uniprot id: A0A6J3ENH6
names: Similarity
messages: Belongs to the CKAP2 family.

219594:KCNK15
gene id: 219594:KCNK15
uniprot id: A0A6J3DSW3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
messages: Membrane

219594:INSM2
gene id: 219594:INSM2
uniprot id: A0A6J3D3S1
names: Subcellular Location Annotation
messages: Nucleus

219594:LOC116500137
gene id: 219594:LOC116500137
uniprot id: A0A6J3EG93
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

219594:ENKD1
gene id: 219594:ENKD1
uniprot id: A0A6J3DLK9
names: Subcellular Location Annotation
messages: cilium axoneme

219594:ATAD2B
gene id: 219594:ATAD2B
uniprot id: A0A6J3CN29
uniprot id: A0A6J3CU51
names: Similarity
messages: Belongs to the AAA ATPase family.

219594:GRIN2C
gene id: 219594:GRIN2C
uniprot id: A0A6J3E0G2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Receptor for glutamate that functions as a ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system.
messages: Synaptic cell membrane

219594:NSUN3
gene id: 219594:NSUN3
uniprot id: A0A6J3EPQ6
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.

219594:LOC116489530
gene id: 219594:LOC116489530
uniprot id: A0A6J3D2M6
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane raft

219594:BCAR1
gene id: 219594:BCAR1
uniprot id: A0A6J3DQ82
uniprot id: A0A6J3DQW9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CAS family.
messages: focal adhesion

219594:KIF23
gene id: 219594:KIF23
uniprot id: A0A6J3DI70
uniprot id: A0A6J3DKS1
uniprot id: A0A6J3DMC1
uniprot id: A0A6J3DNP1
uniprot id: A0A6J3DNP6
uniprot id: A0A6J3DPB3
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

219594:SH3BGRL3
gene id: 219594:SH3BGRL3
uniprot id: A0A6J3E3G0
names: Similarity
messages: Belongs to the SH3BGR family.

219594:THOC7
gene id: 219594:THOC7
uniprot id: A0A6J3DE96
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the THOC7 family.
messages: Nucleus
messages: Required for efficient export of polyadenylated RNA. Acts as component of the THO subcomplex of the TREX complex which is thought to couple mRNA transcription, processing and nuclear export, and which specifically associates with spliced mRNA and not with unspliced pre-mRNA. TREX is recruited to spliced mRNAs by a transcription-independent mechanism, binds to mRNA upstream of the exon-junction complex (EJC) and is recruited in a splicing- and cap-dependent manner to a region near the 5' end of the mRNA where it functions in mRNA export to the cytoplasm via the TAP/NFX1 pathway.

219594:ZRANB1
gene id: 219594:ZRANB1
uniprot id: A0A6J3D8M1
names: Similarity
messages: Belongs to the peptidase C64 family.

219594:HCFC2
gene id: 219594:HCFC2
uniprot id: A0A6J3CTH9
names: Subcellular Location Annotation
messages: Nucleus

219594:SNAP25
gene id: 219594:SNAP25
uniprot id: A0A6J3CPB0
uniprot id: A0A6J3CQ47
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNAP-25 family.
messages: Cell membrane
messages: Plays an important role in the synaptic function of specific neuronal systems. Associates with proteins involved in vesicle docking and membrane fusion.
messages: synaptosome

219594:LYG2
gene id: 219594:LYG2
uniprot id: A0A6J3EJM2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 23 family.
messages: Secreted

219594:HMGN3
gene id: 219594:HMGN3
uniprot id: A0A6J3CRN1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HMGN family.
messages: Nucleus

219594:EDEM3
gene id: 219594:EDEM3
uniprot id: A0A6J3D8Z8
uniprot id: A0A6J3DCM0
uniprot id: A0A6J3DEX0
names: Similarity
messages: Belongs to the glycosyl hydrolase 47 family.

219594:NAV2
gene id: 219594:NAV2
uniprot id: A0A6J3CWR1
uniprot id: A0A6J3CWR6
uniprot id: A0A6J3CYZ8
uniprot id: A0A6J3CZA5
uniprot id: A0A6J3D1J6
uniprot id: A0A6J3D2N6
uniprot id: A0A6J3D2P1
names: Similarity
messages: Belongs to the Nav/unc-53 family.

219594:MTMR8
gene id: 219594:MTMR8
uniprot id: A0A6J3DRU7
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily.

219594:CYTB
gene id: 219594:CYTB
uniprot id: A0A068L8U7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome b family.
messages: Binds 2 heme groups non-covalently.
messages: Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain. The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c. Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
messages: Membrane
messages: Mitochondrion inner membrane

219594:PIK3C2G
gene id: 219594:PIK3C2G
uniprot id: A0A6J3EQF5
names: Similarity
messages: Belongs to the PI3/PI4-kinase family. Type III PI4K subfamily.

219594:AP2B1
gene id: 219594:AP2B1
uniprot id: A0A6J3E422
names: Similarity
messages: Belongs to the adaptor complexes large subunit family.

219594:DEGS1
gene id: 219594:DEGS1
uniprot id: A0A6J3CQ26
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fatty acid desaturase type 1 family. DEGS subfamily.
messages: Endoplasmic reticulum membrane
messages: Membrane

219594:LOC116495036
gene id: 219594:LOC116495036
uniprot id: A0A6J3DT21
names: Subcellular Location Annotation
messages: Secreted

219594:MFSD10
gene id: 219594:MFSD10
uniprot id: A0A6J3CYS9
names: Subcellular Location Annotation
messages: Membrane

219594:SMARCA5
gene id: 219594:SMARCA5
uniprot id: A0A6J3CVJ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNF2/RAD54 helicase family. ISWI subfamily.
messages: Nucleus

219594:NEFH
gene id: 219594:NEFH
uniprot id: A0A6J3DY59
names: Similarity
messages: Belongs to the intermediate filament family.

219594:DNAAF4
gene id: 219594:DNAAF4
uniprot id: A0A6J3DKB9
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Dynein axonemal particle
messages: neuron projection

219594:SSU72
gene id: 219594:SSU72
uniprot id: A0A6J3E166
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SSU72 phosphatase family.
messages: Nucleus
messages: Protein phosphatase that catalyzes the dephosphorylation of the C-terminal domain of RNA polymerase II. Plays a role in RNA processing and termination.

219594:SVOPL
gene id: 219594:SVOPL
uniprot id: A0A6J3CNT7
names: Subcellular Location Annotation
messages: Membrane

219594:TSEN54
gene id: 219594:TSEN54
uniprot id: A0A6J3E1L5
names: Similarity
messages: Belongs to the SEN54 family.

219594:SLC6A2
gene id: 219594:SLC6A2
uniprot id: A0A6J3DJK5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

219594:WASF3
gene id: 219594:WASF3
uniprot id: A0A6J3DP20
uniprot id: A0A6J3DQ93
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SCAR/WAVE family.
messages: Binds actin and the Arp2/3 complex.
messages: Downstream effector molecule involved in the transmission of signals from tyrosine kinase receptors and small GTPases to the actin cytoskeleton. Promotes formation of actin filaments. Part of the WAVE complex that regulates lamellipodia formation. The WAVE complex regulates actin filament reorganization via its interaction with the Arp2/3 complex.
messages: cytoskeleton

219594:ACAD9
gene id: 219594:ACAD9
uniprot id: A0A6J3DE35
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

219594:HNRNPDL
gene id: 219594:HNRNPDL
uniprot id: A0A6J3CWP9
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

219594:GRAMD1C
gene id: 219594:GRAMD1C
uniprot id: A0A6J3EJL6
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

219594:THPO
gene id: 219594:THPO
uniprot id: A0A6J3DIK4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPO/TPO family.
messages: Secreted

219594:RPL35A
gene id: 219594:RPL35A
uniprot id: A0A6J3DD18
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL33 family.

219594:LOC116501338
gene id: 219594:LOC116501338
uniprot id: A0A6J3EHP5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

219594:SCML2
gene id: 219594:SCML2
uniprot id: A0A6J3EI83
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SCM family.
messages: Nucleus

219594:S100A16
gene id: 219594:S100A16
uniprot id: A0A6J3EF54
names: Similarity
messages: Belongs to the S-100 family.

219594:UBAP2
gene id: 219594:UBAP2
uniprot id: A0A6J3EC08
uniprot id: A0A6J3EGS8
names: Subcellular Location Annotation
messages: Cytoplasm

219594:HMGCL
gene id: 219594:HMGCL
uniprot id: A0A6J3E7M4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HMG-CoA lyase family.
messages: Homodimer; disulfide-linked. Can also form homotetramers.
messages: Mitochondrial 3-hydroxymethyl-3-methylglutaryl-CoA lyase that catalyzes a cation-dependent cleavage of (S)-3-hydroxy-3-methylglutaryl-CoA into acetyl-CoA and acetoacetate, a key step in ketogenesis. Terminal step in leucine catabolism. Ketone bodies (beta-hydroxybutyrate, acetoacetate and acetone) are essential as an alternative source of energy to glucose, as lipid precursors and as regulators of metabolism.

219594:KIF1A
gene id: 219594:KIF1A
uniprot id: A0A6J3DDE8
uniprot id: A0A6J3DDF3
uniprot id: A0A6J3DDF8
uniprot id: A0A6J3DDG9
uniprot id: A0A6J3DG52
uniprot id: A0A6J3DG56
uniprot id: A0A6J3DG60
uniprot id: A0A6J3DG65
uniprot id: A0A6J3DHC2
uniprot id: A0A6J3DHD3
uniprot id: A0A6J3DHE0
uniprot id: A0A6J3DHE5
uniprot id: A0A6J3DIY9
uniprot id: A0A6J3DIZ5
uniprot id: A0A6J3DJ00
uniprot id: A0A6J3DJ06
uniprot id: A0A6J3DJI7
uniprot id: A0A6J3DJJ2
uniprot id: A0A6J3DJJ8
uniprot id: A0A6J3DJK3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.
messages: axon

219594:PAQR5
gene id: 219594:PAQR5
uniprot id: A0A6J3DHM1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ADIPOR family.
messages: Membrane

219594:CAP1
gene id: 219594:CAP1
uniprot id: A0A6J3E800
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CAP family.
messages: Cell membrane

219594:PAQR8
gene id: 219594:PAQR8
uniprot id: A0A6J3CU84
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ADIPOR family.
messages: Membrane

219594:LSM3
gene id: 219594:LSM3
uniprot id: A0A6J3DJL9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the snRNP Sm proteins family.
messages: Binds specifically to the 3'-terminal U-tract of U6 snRNA.
messages: LSm subunits form a heteromer with a doughnut shape.
messages: Nucleus

219594:AMH
gene id: 219594:AMH
uniprot id: A0A6J3ECX1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TGF-beta family.
messages: Homodimer; disulfide-linked.
messages: Secreted

219594:PEX14
gene id: 219594:PEX14
uniprot id: A0A6J3E2S5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peroxin-14 family.
messages: Component of the PEX13-PEX14 docking complex, a translocon channel that specifically mediates the import of peroxisomal cargo proteins bound to PEX5 receptor. The PEX13-PEX14 docking complex forms a large import pore which can be opened to a diameter of about 9 nm. Mechanistically, PEX5 receptor along with cargo proteins associates with the PEX14 subunit of the PEX13-PEX14 docking complex in the cytosol, leading to the insertion of the receptor into the organelle membrane with the concomitant translocation of the cargo into the peroxisome matrix.
messages: Peroxisome membrane

219594:SPSB4
gene id: 219594:SPSB4
uniprot id: A0A6J3DIY1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPSB family.
messages: Cytoplasm

219594:SLC18A3
gene id: 219594:SLC18A3
uniprot id: A0A6J3DC01
names: Subcellular Location Annotation
messages: Membrane

219594:SLC17A6
gene id: 219594:SLC17A6
uniprot id: A0A6J3D4C1
names: Subcellular Location Annotation
messages: Membrane

219594:LOC116499836
gene id: 219594:LOC116499836
uniprot id: A0A6J3EGX5
names: Similarity
messages: Belongs to the glucagon family.

219594:LTA4H
gene id: 219594:LTA4H
uniprot id: A0A6J3EGS0
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M1 family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm

219594:GPR137C
gene id: 219594:GPR137C
uniprot id: A0A6J3D419
names: Subcellular Location Annotation
messages: Lysosome membrane
messages: Membrane

219594:EEF2KMT
gene id: 219594:EEF2KMT
uniprot id: A0A6J3DVL3
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. EEF2KMT family.

219594:XRCC6
gene id: 219594:XRCC6
uniprot id: A0A6J3EFM4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ku70 family.
messages: Nucleus

219594:TOE1
gene id: 219594:TOE1
uniprot id: A0A6J3DBN0
names: Similarity
messages: Belongs to the CAF1 family.

219594:LOC116500130
gene id: 219594:LOC116500130
uniprot id: A0A6J3EFX7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

219594:LOC116496893
gene id: 219594:LOC116496893
uniprot id: A0A6J3DXU0
names: Similarity
messages: Belongs to the GDA1/CD39 NTPase family.

219594:LOC116490528
gene id: 219594:LOC116490528
uniprot id: A0A6J3D8R3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium channel (TC 1.A.1.10) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient.
messages: Membrane

219594:ORMDL2
gene id: 219594:ORMDL2
uniprot id: A0A6J3EH51
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ORM family.
messages: Membrane
messages: Negative regulator of sphingolipid synthesis.

219594:LOC116489778
gene id: 219594:LOC116489778
uniprot id: A0A6J3D1Q5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protease inhibitor I39 (alpha-2-macroglobulin) family.
messages: Secreted

219594:GLB1
gene id: 219594:GLB1
uniprot id: A0A6J3CEW8
names: Similarity
messages: Belongs to the glycosyl hydrolase 35 family.

219594:FAM131B
gene id: 219594:FAM131B
uniprot id: A0A6J3EQF2
names: Similarity
messages: Belongs to the FAM131 family.

219594:SLC7A14
gene id: 219594:SLC7A14
uniprot id: A0A6J3DFT4
names: Subcellular Location Annotation
messages: Membrane

219594:CASP2
gene id: 219594:CASP2
uniprot id: A0A6J3EQL2
names: Similarity
messages: Belongs to the peptidase C14A family.

219594:LOC116494458
gene id: 219594:LOC116494458
uniprot id: A0A6J3DQK0
uniprot id: A0A6J3DRL8
names: Subcellular Location Annotation
messages: Nucleus

219594:KCND2
gene id: 219594:KCND2
uniprot id: A0A6J3CUI2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the potassium channel family. D (Shal) (TC 1.A.1.2) subfamily. Kv4.2/KCND2 sub-subfamily.
messages: Cell junction
messages: Cell membrane
messages: Membrane
messages: Perikaryon
messages: Postsynaptic cell membrane
messages: Synapse
messages: Synaptic cell membrane
messages: dendrite
messages: dendritic spine

219594:SLC35A3
gene id: 219594:SLC35A3
uniprot id: A0A6J3DAI0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleotide-sugar transporter family. SLC35A subfamily.
messages: Golgi apparatus membrane
messages: Membrane

219594:ADAMTS7
gene id: 219594:ADAMTS7
uniprot id: A0A6J3DN35
names: Caution
names: Cofactor
names: Subcellular Location Annotation
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

219594:WDR91
gene id: 219594:WDR91
uniprot id: A0A6J3EIB9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat WDR91 family.
messages: Early endosome membrane
messages: Endosome membrane
messages: Late endosome membrane
messages: Membrane

219594:CHRNB4
gene id: 219594:CHRNB4
uniprot id: A0A6J3DKG4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

219594:RANBP17
gene id: 219594:RANBP17
uniprot id: A0A6J3DQM6
uniprot id: A0A6J3DUD6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exportin family.
messages: Cytoplasm
messages: Nucleus

219594:LOC116498562
gene id: 219594:LOC116498562
uniprot id: A0A6J3E6K0
names: Similarity
names: Subunit
messages: Belongs to the avian keratin family.
messages: The avian keratins (F-ker, S-ker, C-ker and B-ker) are a complex mixture of very similar polypeptides.

219594:BABAM1
gene id: 219594:BABAM1
uniprot id: A0A6J3EE12
names: Subcellular Location Annotation
messages: Nucleus

219594:LOC116498581
gene id: 219594:LOC116498581
uniprot id: A0A6J3EA97
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

219594:SEMA5B
gene id: 219594:SEMA5B
uniprot id: A0A6J3D5I5
uniprot id: A0A6J3D7R6
uniprot id: A0A6J3D8K4
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:GET4
gene id: 219594:GET4
uniprot id: A0A6J3DV31
names: Similarity
messages: Belongs to the GET4 family.

219594:SLC4A5
gene id: 219594:SLC4A5
uniprot id: A0A6J3E8G8
names: Similarity
names: Subcellular Location Annotation
messages: Basolateral cell membrane
messages: Belongs to the anion exchanger (TC 2.A.31) family.
messages: Cell membrane
messages: Lateral cell membrane
messages: Membrane

219594:SCTR
gene id: 219594:SCTR
uniprot id: A0A6J3D4C6
names: Subcellular Location Annotation
messages: Membrane

219594:SLC39A5
gene id: 219594:SLC39A5
uniprot id: A0A6J3EBM3
names: Subcellular Location Annotation
messages: Membrane

219594:MYLK2
gene id: 219594:MYLK2
uniprot id: A0A6J3DYV6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family.
messages: Cytoplasm
messages: May interact with centrin.

219594:USP7
gene id: 219594:USP7
uniprot id: A0A6J3DV99
names: Similarity
messages: Belongs to the peptidase C19 family.

219594:LOC116489570
gene id: 219594:LOC116489570
uniprot id: A0A6J3D0C8
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

219594:FREM1
gene id: 219594:FREM1
uniprot id: A0A6J3EFQ7
uniprot id: A0A6J3EJB2
uniprot id: A0A6J3EJF4
uniprot id: A0A6J3EJG1
uniprot id: A0A6J3EL07
uniprot id: A0A6J3EL12
names: Similarity
messages: Belongs to the FRAS1 family.

219594:PPIH
gene id: 219594:PPIH
uniprot id: A0A6J3E7J0
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

219594:AZIN1
gene id: 219594:AZIN1
uniprot id: A0A6J3CHC9
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family.

219594:MPL
gene id: 219594:MPL
uniprot id: A0A6J3DFC3
names: Similarity
messages: Belongs to the type I cytokine receptor family. Type 1 subfamily.

219594:DDX41
gene id: 219594:DDX41
uniprot id: A0A6J3DUR9
names: Similarity
messages: Belongs to the DEAD box helicase family. DDX41 subfamily.

219594:FAM189A1
gene id: 219594:FAM189A1
uniprot id: A0A6J3DMR9
names: Similarity
messages: Belongs to the ENTREP family.

219594:ST8SIA3
gene id: 219594:ST8SIA3
uniprot id: A0A6J3EDT8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

219594:AKR1A1
gene id: 219594:AKR1A1
uniprot id: A0A6J3DED1
names: Similarity
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Belongs to the aldo/keto reductase family.
messages: Cell membrane
messages: Membrane
messages: cytosol

219594:FAM166A
gene id: 219594:FAM166A
uniprot id: A0A6J3E3P3
names: Similarity
messages: Belongs to the CIMIP2 family.

219594:HSBP1
gene id: 219594:HSBP1
uniprot id: A0A6J3DJE6
names: Similarity
messages: Belongs to the HSBP1 family.

219594:UBA52
gene id: 219594:UBA52
uniprot id: A0A6J3EBU3
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the C-terminal section; belongs to the eukaryotic ribosomal protein eL40 family.
messages: In the N-terminal section; belongs to the ubiquitin family.
messages: Nucleus

219594:VSX1
gene id: 219594:VSX1
uniprot id: A0A6J3CKE6
names: Subcellular Location Annotation
messages: Nucleus

219594:IL17C
gene id: 219594:IL17C
uniprot id: A0A6J3DM77
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IL-17 family.
messages: Secreted

219594:ANAPC5
gene id: 219594:ANAPC5
uniprot id: A0A6J3DWK8
uniprot id: A0A6J3DYX0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the APC5 family.
messages: Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains.
messages: spindle

219594:LOC116491839
gene id: 219594:LOC116491839
uniprot id: A0A6J3DFA9
names: Similarity
messages: Belongs to the cytochrome P450 family.

219594:LOC116488294
gene id: 219594:LOC116488294
uniprot id: A0A6J3CXK6
names: Similarity
messages: Belongs to the peptidase C2 family.

219594:LOC116500504
gene id: 219594:LOC116500504
uniprot id: A0A6J3ECL1
names: Caution
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:ASPHD2
gene id: 219594:ASPHD2
uniprot id: A0A6J3DY57
names: Similarity
messages: Belongs to the aspartyl/asparaginyl beta-hydroxylase family.

219594:BAP1
gene id: 219594:BAP1
uniprot id: A0A6J3DKY6
uniprot id: A0A6J3DLG0
names: Similarity
messages: Belongs to the peptidase C12 family.

219594:RPS17
gene id: 219594:RPS17
uniprot id: A0A6J3DI77
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS17 family.

219594:ARHGEF2
gene id: 219594:ARHGEF2
uniprot id: A0A6J3EA35
uniprot id: A0A6J3EEU3
uniprot id: A0A6J3EF57
uniprot id: A0A6J3EGV9
names: Subcellular Location Annotation
messages: Cytoplasmic vesicle
messages: Golgi apparatus
messages: Vesicle
messages: spindle
messages: tight junction

219594:KMT2C
gene id: 219594:KMT2C
uniprot id: A0A6J3CEK2
uniprot id: A0A6J3CG91
uniprot id: A0A6J3CH64
uniprot id: A0A6J3CH72
uniprot id: A0A6J3CJ46
uniprot id: A0A6J3CJ51
uniprot id: A0A6J3CKU1
uniprot id: A0A6J3CKU6
names: Subcellular Location Annotation
messages: Nucleus

219594:MARCO
gene id: 219594:MARCO
uniprot id: A0A6J3D827
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

219594:LOC116499542
gene id: 219594:LOC116499542
uniprot id: A0A6J3EE57
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

219594:IAPP
gene id: 219594:IAPP
uniprot id: A0A6J3DZG1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calcitonin family.
messages: Secreted

219594:MAT2B
gene id: 219594:MAT2B
uniprot id: A0A6J3DN36
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family. MAT2B subfamily.
messages: Heterotrimer; composed of a catalytic MAT2A homodimer that binds one regulatory MAT2B chain. Heterohexamer; composed of a central, catalytic MAT2A homotetramer flanked on either side by a regulatory MAT2B chain. NADP binding increases the affinity for MAT2A.
messages: Regulatory subunit of S-adenosylmethionine synthetase 2, an enzyme that catalyzes the formation of S-adenosylmethionine from methionine and ATP. Regulates MAT2A catalytic activity by changing its kinetic properties, increasing its affinity for L-methionine.

219594:SMCO4
gene id: 219594:SMCO4
uniprot id: A0A6J3E5F3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SMCO4 family.
messages: Membrane

219594:PUS7
gene id: 219594:PUS7
uniprot id: A0A6J3DIM2
uniprot id: A0A6J3DIP1
uniprot id: A0A6J3DIQ1
uniprot id: A0A6J3DK04
names: Similarity
messages: Belongs to the pseudouridine synthase TruD family.

219594:OGFOD1
gene id: 219594:OGFOD1
uniprot id: A0A6J3DM97
names: Similarity
messages: Belongs to the TPA1 family.

219594:DPM1
gene id: 219594:DPM1
uniprot id: A0A6J3DUH1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycosyltransferase 2 family.
messages: Component of the dolichol-phosphate mannose (DPM) synthase complex.
messages: Endoplasmic reticulum
messages: Transfers mannose from GDP-mannose to dolichol monophosphate to form dolichol phosphate mannose (Dol-P-Man) which is the mannosyl donor in pathways leading to N-glycosylation, glycosyl phosphatidylinositol membrane anchoring, and O-mannosylation of proteins; catalytic subunit of the dolichol-phosphate mannose (DPM) synthase complex.

219594:HARBI1
gene id: 219594:HARBI1
uniprot id: A0A6J3CY97
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HARBI1 family.
messages: Cytoplasm
messages: Nucleus
messages: Transposase-derived protein that may have nuclease activity (Potential). Does not have transposase activity.

219594:COMP
gene id: 219594:COMP
uniprot id: A0A6J3ED30
names: Caution
names: Similarity
messages: Belongs to the thrombospondin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:ROPN1L
gene id: 219594:ROPN1L
uniprot id: A0A6J3CJD2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ropporin family.
messages: flagellum

219594:DUT
gene id: 219594:DUT
uniprot id: A0A6J3DHW1
uniprot id: A0A6J3DLZ7
names: Function
names: Similarity
messages: Belongs to the dUTPase family.
messages: Involved in nucleotide metabolism via production of dUMP, the immediate precursor of thymidine nucleotides, and decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

219594:SLC26A8
gene id: 219594:SLC26A8
uniprot id: A0A6J3EAM5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Membrane

219594:MCRIP1
gene id: 219594:MCRIP1
uniprot id: A0A6J3E1J7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MCRIP family.
messages: Nucleus
messages: Stress granule

219594:CTSL
gene id: 219594:CTSL
uniprot id: A0A6J3EKW7
names: Similarity
messages: Belongs to the peptidase C1 family.

219594:LOC116497548
gene id: 219594:LOC116497548
uniprot id: A0A6J3E0Y3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Receptor for glutamate that functions as a ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system.

219594:PKP1
gene id: 219594:PKP1
uniprot id: A0A6J3E6F1
names: Similarity
messages: Belongs to the beta-catenin family.

219594:FAM163A
gene id: 219594:FAM163A
uniprot id: A0A6J3DFS5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAM163 family.
messages: Membrane

219594:ATG3
gene id: 219594:ATG3
uniprot id: A0A6J3EPL0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATG3 family.
messages: Cytoplasm

219594:MVB12B
gene id: 219594:MVB12B
uniprot id: A0A6J3DXF0
uniprot id: A0A6J3DZ61
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MVB12 family.
messages: Endosome membrane
messages: Late endosome membrane
messages: Membrane

219594:IRX2
gene id: 219594:IRX2
uniprot id: A0A6J3CN04
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TALE/IRO homeobox family.
messages: Nucleus

219594:PIGS
gene id: 219594:PIGS
uniprot id: A0A6J3E0X7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PIGS family.
messages: Endoplasmic reticulum membrane
messages: Membrane

219594:LOC116493720
gene id: 219594:LOC116493720
uniprot id: A0A6J3DMC5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome c oxidase subunit 5A family.
messages: Component of the cytochrome c oxidase (complex IV, CIV), a multisubunit enzyme composed of a catalytic core of 3 subunits and several supernumerary subunits. The complex exists as a monomer or a dimer and forms supercomplexes (SCs) in the inner mitochondrial membrane with ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII).
messages: Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)). The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
messages: Mitochondrion inner membrane

219594:ATP5PO
gene id: 219594:ATP5PO
uniprot id: A0A6J3DE82
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase delta chain family.
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain and the peripheric stalk, which acts as a stator to hold the catalytic alpha(3)beta(3) subcomplex and subunit a/ATP6 static relative to the rotary elements.
messages: Mitochondrion inner membrane

219594:ZDHHC5
gene id: 219594:ZDHHC5
uniprot id: A0A6J3D214
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

219594:PCSK4
gene id: 219594:PCSK4
uniprot id: A0A6J3ED16
names: Similarity
messages: Belongs to the peptidase S8 family.

219594:NCAPG
gene id: 219594:NCAPG
uniprot id: A0A6J3CYI2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CND3 (condensin subunit 3) family.
messages: Chromosome

219594:FABP2
gene id: 219594:FABP2
uniprot id: A0A6J3CXJ9
names: Similarity
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.

219594:PWP2
gene id: 219594:PWP2
uniprot id: A0A6J3EHL9
uniprot id: A0A6J3EJH1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat PWP2 family.
messages: nucleolus

219594:DCAF1
gene id: 219594:DCAF1
uniprot id: A0A6J3DEY3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VPRBP/DCAF1 family.
messages: Nucleus

219594:LOC116494635
gene id: 219594:LOC116494635
uniprot id: A0A6J3DM02
uniprot id: A0A6J3DS70
names: Similarity
messages: Belongs to the SLAIN motif-containing family.

219594:CSNK1G2
gene id: 219594:CSNK1G2
uniprot id: A0A6J3E7K4
uniprot id: A0A6J3E937
names: Similarity
messages: Belongs to the protein kinase superfamily. CK1 Ser/Thr protein kinase family. Casein kinase I subfamily.

219594:LOC116501339
gene id: 219594:LOC116501339
uniprot id: A0A6J3EG88
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

219594:P2RY2
gene id: 219594:P2RY2
uniprot id: A0A6J3EQW3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

219594:PRRC1
gene id: 219594:PRRC1
uniprot id: A0A6J3EI58
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRRC1 family.
messages: Golgi apparatus

219594:ZRANB2
gene id: 219594:ZRANB2
uniprot id: A0A6J3DF95
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZRANB2 family.
messages: May interfere with constitutive 5'-splice site selection.
messages: Nucleus

219594:TLE3
gene id: 219594:TLE3
uniprot id: A0A6J3DHY1
uniprot id: A0A6J3DKI7
uniprot id: A0A6J3DM25
uniprot id: A0A6J3DNF3
uniprot id: A0A6J3DNF8
uniprot id: A0A6J3DP25
uniprot id: A0A6J3DP27
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat Groucho/TLE family.
messages: Nucleus

219594:LOC116499833
gene id: 219594:LOC116499833
uniprot id: A0A6J3EA54
names: Similarity
messages: Belongs to the intermediate filament family.

219594:PHF10
gene id: 219594:PHF10
uniprot id: A0A6J3CM23
uniprot id: A0A6J3CN60
uniprot id: A0A6J3CQE0
uniprot id: A0A6J3CRG4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SAYP family.
messages: Nucleus

219594:NSRP1
gene id: 219594:NSRP1
uniprot id: A0A6J3DZV2
uniprot id: A0A6J3E5Y8
names: Similarity
messages: Belongs to the NSRP1 family.

219594:ATP5IF1
gene id: 219594:ATP5IF1
uniprot id: A0A6J3EAD5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase inhibitor family.
messages: Endogenous F(1)F(o)-ATPase inhibitor limiting ATP depletion when the mitochondrial membrane potential falls below a threshold and the F(1)F(o)-ATP synthase starts hydrolyzing ATP to pump protons out of the mitochondrial matrix. Required to avoid the consumption of cellular ATP when the F(1)F(o)-ATP synthase enzyme acts as an ATP hydrolase.
messages: Forms an alpha-helical dimer with monomers associated via an antiparallel alpha-helical coiled coil, leaving each N-terminal inhibitory region accessible for interaction with an F1 catalytic domain. The inhibitory N-terminal region binds the alpha(ADP-bound)-beta(ADP-bound) (ATP5F1A-ATP5F1B) interface of F1-ATPase, and also contact the central gamma subunit (ATP5F1C). This dimeric state is favored by pH values below 7.0, and at higher values the dimers associate to form inactive homotetramer, where the inhibitory region is occluded, masking its inhibitory activity.
messages: Homodimer; represents the active form and is present at a pH value below 6.5. Homotetramer; represents the inactive form and is present at a pH value above 7.0.
messages: Indirectly acts as a regulator of heme synthesis in erythroid tissues: regulates heme synthesis by modulating the mitochondrial pH and redox potential, allowing fech to efficiently catalyze the incorporation of iron into protoporphyrin IX to produce heme.
messages: Mitochondrion

219594:BAZ1A
gene id: 219594:BAZ1A
uniprot id: A0A6J3D502
names: Subcellular Location Annotation
messages: Nucleus

219594:LOC116488132
gene id: 219594:LOC116488132
uniprot id: A0A6J3CTD9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. Very large inducible GTPase (VLIG) family.
messages: Nucleus

219594:LOC116502097
gene id: 219594:LOC116502097
uniprot id: A0A6J3EPC4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CFAP298 family.
messages: cilium basal body

219594:MED20
gene id: 219594:MED20
uniprot id: A0A6J3EB70
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 20 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex.
messages: Nucleus

219594:LOC116498321
gene id: 219594:LOC116498321
uniprot id: A0A6J3E979
names: Similarity
names: Subunit
messages: Belongs to the avian keratin family.
messages: The avian keratins (F-ker, S-ker, C-ker and B-ker) are a complex mixture of very similar polypeptides.

219594:GPR61
gene id: 219594:GPR61
uniprot id: A0A6J3E642
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

219594:LSM14B
gene id: 219594:LSM14B
uniprot id: A0A6J3DU40
uniprot id: A0A6J3DWB8
uniprot id: A0A6J3DY60
names: Similarity
messages: Belongs to the LSM14 family.

219594:DLX6
gene id: 219594:DLX6
uniprot id: A0A6J3CQR0
names: Subcellular Location Annotation
messages: Nucleus

219594:HTR1E
gene id: 219594:HTR1E
uniprot id: A0A6J3CNZ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

219594:DPH3
gene id: 219594:DPH3
uniprot id: A0A6J3CK37
names: Similarity
messages: Belongs to the DPH3 family.

219594:CTNNA1
gene id: 219594:CTNNA1
uniprot id: A0A6J3DM54
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vinculin/alpha-catenin family.
messages: Cell membrane
messages: Membrane
messages: adherens junction

219594:LOC116493530
gene id: 219594:LOC116493530
uniprot id: A0A6J3DNI0
names: Similarity
messages: Belongs to the intermediate filament family.

219594:GALK2
gene id: 219594:GALK2
uniprot id: A0A6J3DGP5
uniprot id: A0A6J3DJB0
uniprot id: A0A6J3DMR6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. GalK subfamily.
messages: Nucleus

219594:TPM2
gene id: 219594:TPM2
uniprot id: A0A6J3EED6
uniprot id: A0A6J3EEE1
uniprot id: A0A6J3EFU1
uniprot id: A0A6J3EFU6
uniprot id: A0A6J3EFV1
uniprot id: A0A6J3EGR7
uniprot id: A0A6J3EI99
uniprot id: A0A6J3EJF5
uniprot id: A0A6J3EJJ8
uniprot id: A0A6J3EL51
uniprot id: A0A6J3EL56
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tropomyosin family.
messages: cytoskeleton

219594:CETP
gene id: 219594:CETP
uniprot id: A0A6J3DML9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BPI/LBP/Plunc superfamily. BPI/LBP family.
messages: Secreted

219594:MRPS15
gene id: 219594:MRPS15
uniprot id: A0A6J3E4P8
names: Similarity
messages: Belongs to the universal ribosomal protein uS15 family.

219594:TRAPPC3
gene id: 219594:TRAPPC3
uniprot id: A0A6J3E3M1
uniprot id: A0A6J3E7Y6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAPP small subunits family. BET3 subfamily.
messages: Endoplasmic reticulum
messages: Homodimer.
messages: May play a role in vesicular transport from endoplasmic reticulum to Golgi.
messages: cis-Golgi network

219594:LAMTOR2
gene id: 219594:LAMTOR2
uniprot id: A0A6J3E9K1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GAMAD family.
messages: Endosome membrane
messages: Late endosome membrane
messages: Lysosome membrane

219594:NPBWR2
gene id: 219594:NPBWR2
uniprot id: A0A6J3DS08
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

219594:NAGA
gene id: 219594:NAGA
uniprot id: A0A6J3EQ18
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycosyl hydrolase 27 family.
messages: Homodimer.
messages: Lysosome

219594:LOC116501419
gene id: 219594:LOC116501419
uniprot id: A0A6J3EGK0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

219594:HEXA
gene id: 219594:HEXA
uniprot id: A0A6J3DJZ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 20 family.
messages: Lysosome

219594:KIF3B
gene id: 219594:KIF3B
uniprot id: A0A6J3DRH0
uniprot id: A0A6J3DTN5
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

219594:ZFPM2
gene id: 219594:ZFPM2
uniprot id: A0A6J3CIL1
names: Subcellular Location Annotation
messages: Nucleus

219594:SKA2
gene id: 219594:SKA2
uniprot id: A0A6J3E3W3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SKA2 family.
messages: spindle

219594:UFM1
gene id: 219594:UFM1
uniprot id: A0A6J3DCA7
names: Function
names: Similarity
messages: Belongs to the UFM1 family.
messages: Ubiquitin-like modifier which can be covalently attached via an isopeptide bond to lysine residues of substrate proteins as a monomer or a lysine-linked polymer. Ufmylation is involved in reticulophagy (also called ER-phagy) induced in response to endoplasmic reticulum stress.

219594:HRH3
gene id: 219594:HRH3
uniprot id: A0A6J3DSM3
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

219594:RPF2
gene id: 219594:RPF2
uniprot id: A0A6J3CSB9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RPF2 family.
messages: nucleolus

219594:MFSD8
gene id: 219594:MFSD8
uniprot id: A0A6J3D2A1
names: Subcellular Location Annotation
messages: Membrane

219594:TMEM205
gene id: 219594:TMEM205
uniprot id: A0A6J3DC89
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM205 family.
messages: Membrane

219594:GPBP1
gene id: 219594:GPBP1
uniprot id: A0A6J3EDK4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vasculin family.
messages: Nucleus

219594:CRYAA
gene id: 219594:CRYAA
uniprot id: A0A6J3E9K5
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

219594:AARS1
gene id: 219594:AARS1
uniprot id: A0A6J3DPF9
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Alax-L subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Monomer. Interacts with ANKRD16; the interaction is direct.

219594:LOC116498349
gene id: 219594:LOC116498349
uniprot id: A0A6J3EAQ7
names: Similarity
names: Subunit
messages: Belongs to the avian keratin family.
messages: The avian keratins (F-ker, S-ker, C-ker and B-ker) are a complex mixture of very similar polypeptides.

219594:ATXN10
gene id: 219594:ATXN10
uniprot id: A0A6J3DCG4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ataxin-10 family.
messages: Necessary for the survival of cerebellar neurons. Induces neuritogenesis by activating the Ras-MAP kinase pathway. May play a role in the maintenance of a critical intracellular glycosylation level and homeostasis.
messages: perinuclear region

219594:TTI2
gene id: 219594:TTI2
uniprot id: A0A6J3EDC3
names: Similarity
messages: Belongs to the TTI2 family.

219594:LOC116492460
gene id: 219594:LOC116492460
uniprot id: A0A6J3DF07
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
messages: Cytoplasm

219594:CHGB
gene id: 219594:CHGB
uniprot id: A0A6J3CLV4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromogranin/secretogranin protein family.
messages: Secreted

219594:CACNG3
gene id: 219594:CACNG3
uniprot id: A0A6J3DV00
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily.
messages: Membrane

219594:MAMDC4
gene id: 219594:MAMDC4
uniprot id: A0A6J3E060
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:KIF9
gene id: 219594:KIF9
uniprot id: A0A6J3CFV4
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

219594:LOC116497724
gene id: 219594:LOC116497724
uniprot id: A0A6J3E803
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

219594:TBXA2R
gene id: 219594:TBXA2R
uniprot id: A0A6J3EEH6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

219594:COG7
gene id: 219594:COG7
uniprot id: A0A6J3DQF7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COG7 family.
messages: Golgi apparatus membrane
messages: Membrane

219594:SLAIN2
gene id: 219594:SLAIN2
uniprot id: A0A6J3CTF9
uniprot id: A0A6J3CVS0
uniprot id: A0A6J3CZK8
names: Similarity
messages: Belongs to the SLAIN motif-containing family.

219594:NAGK
gene id: 219594:NAGK
uniprot id: A0A6J3CWZ9
names: Similarity
messages: Belongs to the eukaryotic-type N-acetylglucosamine kinase family.

219594:ENO1
gene id: 219594:ENO1
uniprot id: A0A6J3E1A1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Cytoplasm

219594:ZIC5
gene id: 219594:ZIC5
uniprot id: A0A6J3E5T0
names: Similarity
messages: Belongs to the GLI C2H2-type zinc-finger protein family.

219594:LOC116486841
gene id: 219594:LOC116486841
uniprot id: A0A6J3CME5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the DNA photolyase class-1 family.
messages: Binds 1 5,10-methenyltetrahydrofolate (MTHF) per subunit.
messages: Binds 1 FAD per subunit.
messages: May have a photoreceptor function.

219594:RAB3B
gene id: 219594:RAB3B
uniprot id: A0A6J3DDU7
uniprot id: A0A6J3DEY6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Cell membrane
messages: Protein transport. Probably involved in vesicular traffic.

219594:RABGGTB
gene id: 219594:RABGGTB
uniprot id: A0A6J3DEY5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the protein prenyltransferase subunit beta family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the transfer of a geranylgeranyl moiety from geranylgeranyl diphosphate to both cysteines of proteins with the C-terminal sequence -XXCC, -XCXC and -CCXX.

219594:CIAO2A
gene id: 219594:CIAO2A
uniprot id: A0A6J3DKU0
names: Similarity
messages: Belongs to the MIP18 family.

219594:TMC6
gene id: 219594:TMC6
uniprot id: A0A6J3DY89
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMC family.
messages: Membrane

219594:LOC116497551
gene id: 219594:LOC116497551
uniprot id: A0A6J3E2B6
names: Similarity
messages: Belongs to the 'GDXG' lipolytic enzyme family.

219594:ATRN
gene id: 219594:ATRN
uniprot id: A0A6J3CUR8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:DCBLD1
gene id: 219594:DCBLD1
uniprot id: A0A6J3CRD2
uniprot id: A0A6J3CUC8
uniprot id: A0A6J3CVH3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:ABCA3
gene id: 219594:ABCA3
uniprot id: A0A6J3DTH8
names: Subcellular Location Annotation
messages: Membrane

219594:RFFL
gene id: 219594:RFFL
uniprot id: A0A6J3DZ14
uniprot id: A0A6J3DZ19
names: Subcellular Location Annotation
messages: Cell membrane

219594:ASZ1
gene id: 219594:ASZ1
uniprot id: A0A6J3EGF0
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Interacts with DDX4, PIWIL1, RANBP9 and TDRD1.

219594:BROX
gene id: 219594:BROX
uniprot id: A0A6J3CRA8
names: Similarity
messages: Belongs to the BROX family.

219594:BCL9
gene id: 219594:BCL9
uniprot id: A0A6J3EGA6
uniprot id: A0A6J3EGB9
uniprot id: A0A6J3EGC4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BCL9 family.
messages: Nucleus

219594:UNC93B1
gene id: 219594:UNC93B1
uniprot id: A0A6J3D6W9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the unc-93 family.
messages: Membrane

219594:LOC116495491
gene id: 219594:LOC116495491
uniprot id: A0A6J3DR01
uniprot id: A0A6J3DX58
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

219594:HOXA3
gene id: 219594:HOXA3
uniprot id: A0A6J3CL26
uniprot id: A0A6J3CMQ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Antp homeobox family.
messages: Nucleus

219594:POLR3B
gene id: 219594:POLR3B
uniprot id: A0A6J3E696
names: Function
names: Similarity
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.

219594:DMRT3
gene id: 219594:DMRT3
uniprot id: A0A6J3ELC2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DMRT family.
messages: Nucleus

219594:RPS6KB2
gene id: 219594:RPS6KB2
uniprot id: A0A6J3D1H2
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily.

219594:BPNT2
gene id: 219594:BPNT2
uniprot id: A0A6J3CL16
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

219594:ARF1
gene id: 219594:ARF1
uniprot id: A0A6J3CIA3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Arf family.
messages: GTP-binding protein involved in protein trafficking; modulates vesicle budding and uncoating within the Golgi apparatus.
messages: Golgi apparatus

219594:LOC116502113
gene id: 219594:LOC116502113
uniprot id: A0A6J3EPC6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: High affinity receptor for urotensin-2 and urotensin-2B. The activity of this receptor is mediated by a G-protein that activate a phosphatidylinositol-calcium second messenger system.
messages: Membrane

219594:GCFC2
gene id: 219594:GCFC2
uniprot id: A0A6J3CRI4
names: Similarity
messages: Belongs to the GCF family.

219594:LOC116489572
gene id: 219594:LOC116489572
uniprot id: A0A6J3D3V4
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:LOC116496709
gene id: 219594:LOC116496709
uniprot id: A0A6J3E1S7
names: Subcellular Location Annotation
names: Subunit
messages: Cell membrane
messages: Interacts with NCDN.
messages: Membrane

219594:NEXMIF
gene id: 219594:NEXMIF
uniprot id: A0A6J3DSK1
names: Subcellular Location Annotation
messages: Nucleus

219594:LOC116498322
gene id: 219594:LOC116498322
uniprot id: A0A6J3E979
names: Similarity
names: Subunit
messages: Belongs to the avian keratin family.
messages: The avian keratins (F-ker, S-ker, C-ker and B-ker) are a complex mixture of very similar polypeptides.

219594:RECK
gene id: 219594:RECK
uniprot id: A0A6J3CER2
uniprot id: A0A6J3CGE0
names: Subcellular Location Annotation
messages: Secreted

219594:SFXN2
gene id: 219594:SFXN2
uniprot id: A0A6J3DAR8
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sideroflexin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Mitochondrion membrane

219594:MAP2
gene id: 219594:MAP2
uniprot id: A0A6J3D4M4
uniprot id: A0A6J3D4N1
uniprot id: A0A6J3D4N4
uniprot id: A0A6J3D4N9
uniprot id: A0A6J3D7A6
uniprot id: A0A6J3D7B1
uniprot id: A0A6J3D7B8
uniprot id: A0A6J3D7C4
uniprot id: A0A6J3D7T8
uniprot id: A0A6J3D7U3
uniprot id: A0A6J3D7U8
uniprot id: A0A6J3D7V3
uniprot id: A0A6J3DA01
uniprot id: A0A6J3DA07
uniprot id: A0A6J3DA12
uniprot id: A0A6J3DAJ6
uniprot id: A0A6J3DAK1
uniprot id: A0A6J3DAL4
uniprot id: A0A6J3DAL8
names: Subcellular Location Annotation
messages: cytoskeleton

219594:LOC116490558
gene id: 219594:LOC116490558
uniprot id: A0A6J3D344
names: Similarity
messages: Belongs to the peptidase S51 family.

219594:POFUT2
gene id: 219594:POFUT2
uniprot id: A0A6J3D2N0
names: Similarity
messages: Belongs to the glycosyltransferase 68 family.

219594:TRIM2
gene id: 219594:TRIM2
uniprot id: A0A6J3D047
uniprot id: A0A6J3D1A6
names: Similarity
messages: Belongs to the TRIM/RBCC family.

219594:KIF14
gene id: 219594:KIF14
uniprot id: A0A6J3D8D6
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

219594:JPH3
gene id: 219594:JPH3
uniprot id: A0A6J3DN52
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the junctophilin family.
messages: Cell membrane
messages: Endoplasmic reticulum membrane
messages: Junctophilins contribute to the formation of junctional membrane complexes (JMCs) which link the plasma membrane with the endoplasmic or sarcoplasmic reticulum in excitable cells. Provides a structural foundation for functional cross-talk between the cell surface and intracellular calcium release channels.
messages: Membrane

219594:LOC116500175
gene id: 219594:LOC116500175
uniprot id: A0A6J3EGC9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the immunoglobulin superfamily. BTN/MOG family.
messages: Membrane

219594:PKDREJ
gene id: 219594:PKDREJ
uniprot id: A0A6J3CTQ2
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polycystin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

219594:ARRDC3
gene id: 219594:ARRDC3
uniprot id: A0A6J3EID8
names: Similarity
messages: Belongs to the arrestin family.

219594:TMOD4
gene id: 219594:TMOD4
uniprot id: A0A6J3EG53
names: Subcellular Location Annotation
messages: cytoskeleton

219594:WNT8A
gene id: 219594:WNT8A
uniprot id: A0A6J3DQL9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

219594:OTP
gene id: 219594:OTP
uniprot id: A0A6J3EFY3
names: Subcellular Location Annotation
messages: Nucleus

219594:PRDM12
gene id: 219594:PRDM12
uniprot id: A0A6J3E310
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class V-like SAM-binding methyltransferase superfamily.
messages: Involved in the positive regulation of histone H3-K9 dimethylation.
messages: Nucleus

219594:YIPF6
gene id: 219594:YIPF6
uniprot id: A0A6J3DNP3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YIP1 family.
messages: Golgi apparatus membrane
messages: Membrane

219594:FECH
gene id: 219594:FECH
uniprot id: A0A6J3EEB5
uniprot id: A0A6J3EJR8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferrochelatase family.
messages: Catalyzes the ferrous insertion into protoporphyrin IX.
messages: Mitochondrion inner membrane

219594:RSPO3
gene id: 219594:RSPO3
uniprot id: A0A6J3CUT6
names: Similarity
messages: Belongs to the R-spondin family.

219594:KLC1
gene id: 219594:KLC1
uniprot id: A0A6J3D200
uniprot id: A0A6J3D6Z3
uniprot id: A0A6J3D7U0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the kinesin light chain family.
messages: Kinesin is a microtubule-associated force-producing protein that play a role in organelle transport.
messages: Oligomeric complex composed of two heavy chains and two light chains.
messages: cytoskeleton

219594:PHOSPHO1
gene id: 219594:PHOSPHO1
uniprot id: A0A6J3EBD2
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. PHOSPHO family.

219594:DLG3
gene id: 219594:DLG3
uniprot id: A0A6J3DN13
uniprot id: A0A6J3DPU7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MAGUK family.
messages: Membrane

219594:NFYB
gene id: 219594:NFYB
uniprot id: A0A6J3CU21
names: Function
names: Similarity
messages: Belongs to the NFYB/HAP3 subunit family.
messages: Component of the sequence-specific heterotrimeric transcription factor (NF-Y) which specifically recognizes a 5'-CCAAT-3' box motif found in the promoters of its target genes. NF-Y can function as both an activator and a repressor, depending on its interacting cofactors.

219594:PSMC6
gene id: 219594:PSMC6
uniprot id: A0A6J3CYX4
names: Similarity
messages: Belongs to the AAA ATPase family.

219594:FGF4
gene id: 219594:FGF4
uniprot id: A0A6J3D781
names: Similarity
messages: Belongs to the heparin-binding growth factors family.

219594:EVC
gene id: 219594:EVC
uniprot id: A0A6J3CUX7
uniprot id: A0A6J3D120
names: Subcellular Location Annotation
messages: Membrane
messages: cilium basal body
messages: cilium membrane

219594:AIFM1
gene id: 219594:AIFM1
uniprot id: A0A6J3DR36
uniprot id: A0A6J3DRX8
names: Similarity
messages: Belongs to the FAD-dependent oxidoreductase family.

219594:HACD1
gene id: 219594:HACD1
uniprot id: A0A6J3CGT3
uniprot id: A0A6J3CKE5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the very long-chain fatty acids dehydratase HACD family.
messages: Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

219594:SEC61G
gene id: 219594:SEC61G
uniprot id: A0A6J3CNN8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecE/SEC61-gamma family.
messages: Endoplasmic reticulum membrane
messages: Membrane

219594:RPS2
gene id: 219594:RPS2
uniprot id: A0A6J3DWZ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Nucleus

219594:ITPR2
gene id: 219594:ITPR2
uniprot id: A0A6J3CSN9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the InsP3 receptor family.
messages: Endoplasmic reticulum membrane
messages: Homotetramer.
messages: Membrane
messages: Receptor for inositol 1,4,5-trisphosphate, a second messenger that mediates the release of intracellular calcium.
messages: The receptor contains a calcium channel in its C-terminal extremity. Its large N-terminal cytoplasmic region has the ligand-binding site in the N-terminus and modulatory sites in the middle portion immediately upstream of the channel region.

219594:ZGPAT
gene id: 219594:ZGPAT
uniprot id: A0A6J3DZ02
names: Subcellular Location Annotation
messages: Nucleus

219594:ARG2
gene id: 219594:ARG2
uniprot id: A0A6J3D484
names: Cofactor
names: Similarity
messages: Belongs to the arginase family.
messages: Binds 2 manganese ions per subunit.

219594:DOLPP1
gene id: 219594:DOLPP1
uniprot id: A0A6J3DX25
uniprot id: A0A6J3E365
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dolichyldiphosphatase family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Required for efficient N-glycosylation. Necessary for maintaining optimal levels of dolichol-linked oligosaccharides. Hydrolyzes dolichyl pyrophosphate at a very high rate and dolichyl monophosphate at a much lower rate. Does not act on phosphatidate.

219594:NKX2-5
gene id: 219594:NKX2-5
uniprot id: A0A6J3DUT8
names: Subcellular Location Annotation
messages: Nucleus

219594:AGA
gene id: 219594:AGA
uniprot id: A0A6J3CSP7
names: Similarity
messages: Belongs to the Ntn-hydrolase family.

219594:TUBB3
gene id: 219594:TUBB3
uniprot id: A0A6J3DQV4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: cytoskeleton

219594:TFCP2L1
gene id: 219594:TFCP2L1
uniprot id: A0A6J3D4R3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the grh/CP2 family. CP2 subfamily.
messages: Nucleus

219594:TARS2
gene id: 219594:TARS2
uniprot id: A0A6J3EAW7
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.

219594:LOC116491458
gene id: 219594:LOC116491458
uniprot id: A0A6J3DCX3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AB hydrolase superfamily. Lipase family.
messages: Secreted

219594:OLFM2
gene id: 219594:OLFM2
uniprot id: A0A6J3EAZ2
uniprot id: A0A6J3EFQ0
uniprot id: A0A6J3EG08
names: Subcellular Location Annotation
messages: Secreted
messages: Synapse

219594:SERINC5
gene id: 219594:SERINC5
uniprot id: A0A6J3EGS4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TDE1 family.
messages: Membrane

219594:LOC116500155
gene id: 219594:LOC116500155
uniprot id: A0A6J3ECL7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

219594:STMN4
gene id: 219594:STMN4
uniprot id: A0A6J3CQ66
uniprot id: A0A6J3CSE1
uniprot id: A0A6J3CV67
uniprot id: A0A6J3CWA4
names: Similarity
messages: Belongs to the stathmin family.

219594:DNM1
gene id: 219594:DNM1
uniprot id: A0A6J3DYJ3
uniprot id: A0A6J3E078
uniprot id: A0A6J3E081
uniprot id: A0A6J3E2T7
uniprot id: A0A6J3E2U3
uniprot id: A0A6J3E3L0
uniprot id: A0A6J3E3L7
uniprot id: A0A6J3E3M3
uniprot id: A0A6J3E4L9
names: Similarity
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.

219594:TRIM67
gene id: 219594:TRIM67
uniprot id: A0A6J3CNI8
uniprot id: A0A6J3CQH8
uniprot id: A0A6J3CTH3
uniprot id: A0A6J3CUM3
names: Subcellular Location Annotation
messages: cytoskeleton

219594:CZH9orf64
gene id: 219594:CZH9orf64
uniprot id: A0A6J3EK93
names: Function
names: Similarity
messages: Belongs to the QNG1 protein family.
messages: Catalyzes the hydrolysis of queuosine 5'-phosphate, releasing the nucleobase queuine (q). Is required for salvage of queuine from exogenous queuosine (Q) that is imported and then converted to queuosine 5'-phosphate intracellularly.

219594:CPSF2
gene id: 219594:CPSF2
uniprot id: A0A6J3D4E3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. CPSF2/YSH1 subfamily.
messages: Nucleus

219594:VPS36
gene id: 219594:VPS36
uniprot id: A0A6J3DN74
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the VPS36 family.
messages: Component of the ESCRT-II complex (endosomal sorting complex required for transport II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs.
messages: Component of the endosomal sorting complex required for transport II (ESCRT-II).
messages: Cytoplasm
messages: Endosome

219594:TEKT3
gene id: 219594:TEKT3
uniprot id: A0A6J3DY79
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tektin family.
messages: flagellum

219594:ILF3
gene id: 219594:ILF3
uniprot id: A0A6J3EB12
uniprot id: A0A6J3ECD4
uniprot id: A0A6J3ECD9
uniprot id: A0A6J3EFS0
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

219594:LOC116494906
gene id: 219594:LOC116494906
uniprot id: A0A6J3DSL6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Arf family.
messages: centrosome

219594:RAP2B
gene id: 219594:RAP2B
uniprot id: A0A6J3DGJ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Ras family.
messages: Endosome membrane
messages: Recycling endosome membrane

219594:XKR6
gene id: 219594:XKR6
uniprot id: A0A6J3CVN7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the XK family.
messages: Membrane

219594:SPSB3
gene id: 219594:SPSB3
uniprot id: A0A6J3DRL6
names: Function
names: Similarity
messages: Belongs to the SPSB family.
messages: May be a substrate recognition component of a SCF-like ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.

219594:ARHGEF9
gene id: 219594:ARHGEF9
uniprot id: A0A6J3DKG7
uniprot id: A0A6J3DKH1
uniprot id: A0A6J3DMX1
uniprot id: A0A6J3DMX6
uniprot id: A0A6J3DMX8
uniprot id: A0A6J3DPR0
uniprot id: A0A6J3DQW7
uniprot id: A0A6J3DQX2
uniprot id: A0A6J3DRP5
uniprot id: A0A6J3DRQ0
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Acts as guanine nucleotide exchange factor (GEF) for CDC42. Promotes formation of GPHN clusters.
messages: Cytoplasm
messages: Interacts with GPHN.
messages: Postsynaptic density

219594:APEH
gene id: 219594:APEH
uniprot id: A0A6J3DLE0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S9C family.
messages: Cytoplasm
messages: Homotetramer.

219594:LEPR
gene id: 219594:LEPR
uniprot id: A0A6J3DDP2
uniprot id: A0A6J3DGN6
uniprot id: A0A6J3DH03
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type I cytokine receptor family. Type 2 subfamily.
messages: Membrane

219594:NMT2
gene id: 219594:NMT2
uniprot id: A0A6J3CJ65
names: Function
names: Similarity
messages: Adds a myristoyl group to the N-terminal glycine residue of certain cellular proteins.
messages: Belongs to the NMT family.

219594:CCNL1
gene id: 219594:CCNL1
uniprot id: A0A6J3DEK9
names: Similarity
messages: Belongs to the cyclin family.

219594:POLR1A
gene id: 219594:POLR1A
uniprot id: A0A6J3CZX4
names: Function
names: Similarity
messages: Belongs to the RNA polymerase beta' chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.

219594:MTNR1A
gene id: 219594:MTNR1A
uniprot id: A0A6J3CYT5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

219594:YDJC
gene id: 219594:YDJC
uniprot id: A0A6J3DT43
names: Function
names: Similarity
messages: Belongs to the YdjC deacetylase family.
messages: Probably catalyzes the deacetylation of acetylated carbohydrates an important step in the degradation of oligosaccharides.

219594:SHOX
gene id: 219594:SHOX
uniprot id: A0A6J3EPU9
names: Subcellular Location Annotation
messages: Nucleus

219594:UBR4
gene id: 219594:UBR4
uniprot id: A0A6J3E147
names: Similarity
messages: Belongs to the UBR4 family.

219594:AGBL2
gene id: 219594:AGBL2
uniprot id: A0A6J3D022
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M14 family.
messages: cytosol

219594:CCR10
gene id: 219594:CCR10
uniprot id: A0A6J3E930
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

219594:CASQ2
gene id: 219594:CASQ2
uniprot id: A0A6J3EQ47
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calsequestrin family.
messages: Calsequestrin is a high-capacity, moderate affinity, calcium-binding protein and thus acts as an internal calcium store in muscle.
messages: Sarcoplasmic reticulum lumen

219594:METTL2A
gene id: 219594:METTL2A
uniprot id: A0A6J3E9S4
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily. METL family.
messages: S-adenosyl-L-methionine-dependent methyltransferase.

219594:MAU2
gene id: 219594:MAU2
uniprot id: A0A6J3E9H4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SCC4/mau-2 family.
messages: nucleoplasm

219594:GPR65
gene id: 219594:GPR65
uniprot id: A0A6J3D4X1
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

219594:MAGI2
gene id: 219594:MAGI2
uniprot id: A0A6J3CHD0
uniprot id: A0A6J3CHG1
uniprot id: A0A6J3CLW2
names: Subcellular Location Annotation
messages: Membrane

219594:SEPTIN7
gene id: 219594:SEPTIN7
uniprot id: A0A6J3CJY3
uniprot id: A0A6J3CPN5
uniprot id: A0A6J3CQX0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.
messages: Cleavage furrow
messages: Midbody
messages: cilium axoneme
messages: kinetochore
messages: spindle

219594:LANCL3
gene id: 219594:LANCL3
uniprot id: A0A6J3DKH3
names: Similarity
messages: Belongs to the LanC-like protein family.

219594:LOC116489876
gene id: 219594:LOC116489876
uniprot id: A0A6J3D201
names: Domain
names: Subcellular Location Annotation
messages: The N-terminal C2 domain associates with lipid membranes upon calcium binding.
messages: cytosol

219594:BCHE
gene id: 219594:BCHE
uniprot id: A0A6J3DDV6
uniprot id: A0A6J3DJH6
uniprot id: A0A6J3DK02
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type-B carboxylesterase/lipase family.
messages: Secreted

219594:GRIN1
gene id: 219594:GRIN1
uniprot id: A0A6J3DY85
uniprot id: A0A6J3DY90
uniprot id: A0A6J3DY95
uniprot id: A0A6J3E2F8
uniprot id: A0A6J3E2G3
uniprot id: A0A6J3E390
uniprot id: A0A6J3E395
uniprot id: A0A6J3E3A1
uniprot id: A0A6J3E4B7
uniprot id: A0A6J3E4C3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. NR1/GRIN1 subfamily.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Receptor for glutamate that functions as a ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system.

219594:CRYBB2
gene id: 219594:CRYBB2
uniprot id: A0A6J3DUS7
uniprot id: A0A6J3DYV9
names: Similarity
names: Subunit
messages: Belongs to the beta/gamma-crystallin family.
messages: Homo/heterodimer, or complexes of higher-order. The structure of beta-crystallin oligomers seems to be stabilized through interactions between the N-terminal arms.

219594:LOC116501953
gene id: 219594:LOC116501953
uniprot id: A0A6J3ENM7
names: Similarity
messages: Belongs to the glycosyl hydrolase 56 family.

219594:FAM13C
gene id: 219594:FAM13C
uniprot id: A0A6J3DDS9
uniprot id: A0A6J3DE38
names: Similarity
messages: Belongs to the FAM13 family.

219594:THBS4
gene id: 219594:THBS4
uniprot id: A0A6J3EKL4
names: Caution
names: Similarity
messages: Belongs to the thrombospondin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:CITED4
gene id: 219594:CITED4
uniprot id: A0A6J3E595
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CITED family.
messages: Nucleus

219594:FAM32A
gene id: 219594:FAM32A
uniprot id: A0A6J3E8M1
names: Similarity
messages: Belongs to the FAM32 family.

219594:LOC116488617
gene id: 219594:LOC116488617
uniprot id: A0A6J3CSY3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OXA1/ALB3/YidC family.
messages: Membrane

219594:DIPK1A
gene id: 219594:DIPK1A
uniprot id: A0A6J3DAJ8
uniprot id: A0A6J3DG89
names: Similarity
messages: Belongs to the DIPK family.

219594:TCP11L1
gene id: 219594:TCP11L1
uniprot id: A0A6J3D1T5
names: Similarity
messages: Belongs to the TCP11 family.

219594:ITM2B
gene id: 219594:ITM2B
uniprot id: A0A6J3E1V1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ITM2 family.
messages: Membrane

219594:KDM6A
gene id: 219594:KDM6A
uniprot id: A0A6J3CRT0
uniprot id: A0A6J3CRU6
uniprot id: A0A6J3CU73
uniprot id: A0A6J3CUK8
uniprot id: A0A6J3CWW0
uniprot id: A0A6J3CWW7
uniprot id: A0A6J3CX14
uniprot id: A0A6J3CY02
uniprot id: A0A6J3CY05
uniprot id: A0A6J3CY26
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UTX family.
messages: Nucleus

219594:MFAP5
gene id: 219594:MFAP5
uniprot id: A0A6J3DG92
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MFAP family.
messages: extracellular matrix

219594:E2F1
gene id: 219594:E2F1
uniprot id: A0A6J3DSJ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the E2F/DP family.
messages: Nucleus

219594:COPS5
gene id: 219594:COPS5
uniprot id: A0A6J3CQ54
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M67A family. CSN5 subfamily.
messages: synaptic vesicle

219594:LOC116498726
gene id: 219594:LOC116498726
uniprot id: A0A6J3EAT6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

219594:SLC27A4
gene id: 219594:SLC27A4
uniprot id: A0A6J3E2P0
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

219594:TFAP2C
gene id: 219594:TFAP2C
uniprot id: A0A6J3DXJ1
names: Similarity
messages: Belongs to the AP-2 family.

219594:LOC116499204
gene id: 219594:LOC116499204
uniprot id: A0A6J3ECY7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TGF-beta family.
messages: Secreted

219594:SLU7
gene id: 219594:SLU7
uniprot id: A0A6J3DU07
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associated with the spliceosome.
messages: Belongs to the SLU7 family.
messages: Involved in pre-mRNA splicing.
messages: Nucleus

219594:LOC116491302
gene id: 219594:LOC116491302
uniprot id: A0A6J3DCJ4
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZP domain family. ZPB subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Zona pellucida

219594:LOC116490833
gene id: 219594:LOC116490833
uniprot id: A0A6J3D4D2
uniprot id: A0A6J3D7J2
uniprot id: A0A6J3DAA5
names: Similarity
messages: Belongs to the peptidase C14A family.

219594:LOC116486741
gene id: 219594:LOC116486741
uniprot id: A0A6J3CJC1
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily.

219594:PCNA
gene id: 219594:PCNA
uniprot id: A0A6J3EA83
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PCNA family.
messages: Nucleus
messages: This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand.

219594:RRP12
gene id: 219594:RRP12
uniprot id: A0A6J3DE33
names: Similarity
messages: Belongs to the RRP12 family.

219594:GAB1
gene id: 219594:GAB1
uniprot id: A0A6J3CWH7
uniprot id: A0A6J3D1A7
uniprot id: A0A6J3D2F8
names: Similarity
messages: Belongs to the GAB family.

219594:GNA13
gene id: 219594:GNA13
uniprot id: A0A6J3E139
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-alpha family. G(12) subfamily.
messages: Membrane

219594:METTL26
gene id: 219594:METTL26
uniprot id: A0A6J3DVA6
names: Similarity
messages: Belongs to the UPF0585 family.

219594:TGM2
gene id: 219594:TGM2
uniprot id: A0A6J3DYW8
names: Cofactor
names: Similarity
messages: Belongs to the transglutaminase superfamily. Transglutaminase family.
messages: Binds 1 Ca(2+) ion per subunit.

219594:BEGAIN
gene id: 219594:BEGAIN
uniprot id: A0A6J3D133
uniprot id: A0A6J3D4J1
names: Subcellular Location Annotation
messages: Membrane

219594:TATDN1
gene id: 219594:TATDN1
uniprot id: A0A6J3CCX2
uniprot id: A0A6J3CEI4
uniprot id: A0A6J3CFI1
uniprot id: A0A6J3CJ55
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. TatD-type hydrolase family.

219594:GAPDH
gene id: 219594:GAPDH
uniprot id: A0A6J3ECE8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
messages: Has both glyceraldehyde-3-phosphate dehydrogenase and nitrosylase activities, thereby playing a role in glycolysis and nuclear functions, respectively. Glyceraldehyde-3-phosphate dehydrogenase is a key enzyme in glycolysis that catalyzes the first step of the pathway by converting D-glyceraldehyde 3-phosphate (G3P) into 3-phospho-D-glyceroyl phosphate (By similarity). Participates in nuclear events including transcription, RNA transport, DNA replication and apoptosis. Nuclear functions are probably due to the nitrosylase activity that mediates cysteine S-nitrosylation of nuclear target proteins such as SIRT1, HDAC2 and PRKDC.
messages: Homotetramer.
messages: cytosol

219594:PMVK
gene id: 219594:PMVK
uniprot id: A0A6J3E9L5
uniprot id: A0A6J3EEC3
names: Subcellular Location Annotation
messages: cytosol

219594:LOC116502350
gene id: 219594:LOC116502350
uniprot id: A0A6J3EQG4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone H1/H5 family.
messages: Nucleus

219594:LOC116489053
gene id: 219594:LOC116489053
uniprot id: A0A6J3CV90
names: Subcellular Location Annotation
messages: Membrane

219594:ACTR3
gene id: 219594:ACTR3
uniprot id: A0A6J3D734
names: Similarity
messages: Belongs to the actin family.

219594:TAFA2
gene id: 219594:TAFA2
uniprot id: A0A6J3EK41
uniprot id: A0A6J3ELJ6
uniprot id: A0A6J3EQR8
uniprot id: A0A6J3ES17
names: Similarity
messages: Belongs to the TAFA family.

219594:TMEM9B
gene id: 219594:TMEM9B
uniprot id: A0A6J3D5X7
names: Similarity
messages: Belongs to the TMEM9 family.

219594:CTNNB1
gene id: 219594:CTNNB1
uniprot id: A0A6J3CCN5
names: Similarity
messages: Belongs to the beta-catenin family.

219594:LOC116490054
gene id: 219594:LOC116490054
uniprot id: A0A6J3D0I1
names: Domain
names: Subcellular Location Annotation
messages: The N-terminal C2 domain associates with lipid membranes upon calcium binding.
messages: cytosol

219594:PPP2R5D
gene id: 219594:PPP2R5D
uniprot id: A0A6J3CT89
names: Similarity
messages: Belongs to the phosphatase 2A regulatory subunit B56 family.

219594:LOC116491306
gene id: 219594:LOC116491306
uniprot id: A0A6J3D9Z3
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZP domain family. ZPB subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Zona pellucida

219594:POU3F2
gene id: 219594:POU3F2
uniprot id: A0A6J3CUH2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the POU transcription factor family. Class-3 subfamily.
messages: Nucleus

219594:BDH1
gene id: 219594:BDH1
uniprot id: A0A6J3DGH7
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

219594:NID2
gene id: 219594:NID2
uniprot id: A0A6J3CXE0
uniprot id: A0A6J3CZQ2
uniprot id: A0A6J3CZW3
uniprot id: A0A6J3CZW6
uniprot id: A0A6J3D290
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: basement membrane

219594:PIGW
gene id: 219594:PIGW
uniprot id: A0A6J3DZ99
uniprot id: A0A6J3E3J4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PIGW family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Probable acetyltransferase, which acetylates the inositol ring of phosphatidylinositol during biosynthesis of GPI-anchor.

219594:TRAPPC2L
gene id: 219594:TRAPPC2L
uniprot id: A0A6J3DJ92
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAPP small subunits family. Sedlin subfamily.
messages: perinuclear region

219594:PDE1C
gene id: 219594:PDE1C
uniprot id: A0A6J3CFW4
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family. PDE1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

219594:LOC116491322
gene id: 219594:LOC116491322
uniprot id: A0A6J3D9D5
names: Similarity
messages: Belongs to the cytochrome P450 family.

219594:CPEB2
gene id: 219594:CPEB2
uniprot id: A0A6J3CUZ9
names: Similarity
messages: Belongs to the RRM CPEB family.

219594:SEMA3A
gene id: 219594:SEMA3A
uniprot id: A0A6J3CEW5
names: Caution
names: Similarity
messages: Belongs to the semaphorin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:DPM3
gene id: 219594:DPM3
uniprot id: A0A6J3EBB8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DPM3 family.
messages: Component of the dolichol-phosphate mannose (DPM) synthase complex.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Stabilizer subunit of the dolichol-phosphate mannose (DPM) synthase complex; tethers catalytic subunit to the ER.

219594:SYT16
gene id: 219594:SYT16
uniprot id: A0A6J3D2T9
uniprot id: A0A6J3D324
uniprot id: A0A6J3D5C6
names: Similarity
messages: Belongs to the synaptotagmin family.

219594:SLC2A13
gene id: 219594:SLC2A13
uniprot id: A0A6J3CSA3
names: Similarity
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.

219594:SDR42E1
gene id: 219594:SDR42E1
uniprot id: A0A6J3DMF7
uniprot id: A0A6J3DR39
names: Similarity
messages: Belongs to the 3-beta-HSD family.

219594:LOC116491300
gene id: 219594:LOC116491300
uniprot id: A0A6J3D9Y8
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZP domain family. ZPB subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Zona pellucida

219594:ATG9B
gene id: 219594:ATG9B
uniprot id: A0A6J3CKE4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATG9 family.
messages: Membrane
messages: Phospholipid scramblase involved in autophagy. Cycles between the preautophagosomal structure/phagophore assembly site (PAS) and the cytoplasmic vesicle pool and supplies membrane for the growing autophagosome. Lipid scramblase activity plays a key role in preautophagosomal structure/phagophore assembly by distributing the phospholipids that arrive through ATG2 from the cytoplasmic to the luminal leaflet of the bilayer, thereby driving autophagosomal membrane expansion.
messages: Preautophagosomal structure membrane

219594:LOC116494255
gene id: 219594:LOC116494255
uniprot id: A0A6J3DMS1
uniprot id: A0A6J3DMS5
uniprot id: A0A6J3DPK0
uniprot id: A0A6J3DPK4
uniprot id: A0A6J3DQS1
uniprot id: A0A6J3DRJ0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PICALM/SNAP91 family.
messages: Belongs to the prefoldin subunit alpha family.
messages: Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins.
messages: Heterohexamer of two PFD-alpha type and four PFD-beta type subunits.

219594:LOC116496311
gene id: 219594:LOC116496311
uniprot id: A0A6J3DZV0
names: Similarity
messages: Belongs to the MIF family.

219594:ELOVL4
gene id: 219594:ELOVL4
uniprot id: A0A6J3CLH3
uniprot id: A0A6J3CN49
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ELO family.
messages: Belongs to the ELO family. ELOVL4 subfamily.
messages: Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that specifically elongates C24:0 and C26:0 acyl-CoAs. May participate to the production of saturated and monounsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Oligomer.
messages: The C-terminal di-lysine motif may confer endoplasmic reticulum localization.

219594:BFSP2
gene id: 219594:BFSP2
uniprot id: A0A6J3CL59
names: Similarity
messages: Belongs to the intermediate filament family.

219594:LOC116491642
gene id: 219594:LOC116491642
uniprot id: A0A6J3DB09
uniprot id: A0A6J3DBV5
names: Similarity
messages: Belongs to the cytochrome P450 family.

219594:YIPF1
gene id: 219594:YIPF1
uniprot id: A0A6J3DB10
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YIP1 family.
messages: Endosome membrane
messages: Golgi apparatus membrane
messages: Late endosome membrane
messages: Membrane
messages: cis-Golgi network membrane
messages: trans-Golgi network membrane

219594:WDFY1
gene id: 219594:WDFY1
uniprot id: A0A6J3DHE2
uniprot id: A0A6J3DHY8
names: Subcellular Location Annotation
messages: Early endosome
messages: Endosome

219594:C19H9orf78
gene id: 219594:C19H9orf78
uniprot id: A0A6J3E3M9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TLS1 family.
messages: Nucleus

219594:PFDN2
gene id: 219594:PFDN2
uniprot id: A0A6J3EE93
names: Function
names: Similarity
messages: Belongs to the prefoldin subunit beta family.
messages: Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins.

219594:ADAM11
gene id: 219594:ADAM11
uniprot id: A0A6J3E4J0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:FOXM1
gene id: 219594:FOXM1
uniprot id: A0A6J3D6B7
uniprot id: A0A6J3D905
names: Subcellular Location Annotation
messages: Nucleus

219594:LNPK
gene id: 219594:LNPK
uniprot id: A0A6J3D568
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the lunapark family.
messages: Endoplasmic reticulum membrane
messages: Homodimer; homodimerization requires the C4-type zinc finger motif and decreases during mitosis in a phosphorylation-dependent manner.
messages: Plays a role in determining ER morphology.
messages: The C4-type zinc finger motif is necessary both for its ER three-way tubular junction localization and formation.

219594:CNN1
gene id: 219594:CNN1
uniprot id: A0A6J3ECF3
names: Function
names: Similarity
messages: Belongs to the calponin family.
messages: Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity.

219594:ATP6AP1L
gene id: 219594:ATP6AP1L
uniprot id: A0A6J3ELH5
names: Similarity
messages: Belongs to the vacuolar ATPase subunit S1 family.

219594:GADL1
gene id: 219594:GADL1
uniprot id: A0A6J3CM03
uniprot id: A0A6J3CNY6
names: Similarity
names: Subunit
messages: Belongs to the group II decarboxylase family.
messages: Homodimer.

219594:MDM2
gene id: 219594:MDM2
uniprot id: A0A6J3CLL7
uniprot id: A0A6J3CPZ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MDM2/MDM4 family.
messages: Cytoplasm
messages: nucleolus
messages: nucleoplasm

219594:NPNT
gene id: 219594:NPNT
uniprot id: A0A6J3CXN4
uniprot id: A0A6J3CY00
uniprot id: A0A6J3D0A0
uniprot id: A0A6J3D1F5
names: Caution
names: Similarity
messages: Belongs to the nephronectin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:GPD2
gene id: 219594:GPD2
uniprot id: A0A6J3D3N3
uniprot id: A0A6J3D6R4
names: Function
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Calcium-responsive mitochondrial glycerol-3-phosphate dehydrogenase which seems to be a key component of the pancreatic beta-cell glucose-sensing device.

219594:FAM124B
gene id: 219594:FAM124B
uniprot id: A0A6J3DG71
names: Similarity
messages: Belongs to the FAM124 family.

219594:SAP18
gene id: 219594:SAP18
uniprot id: A0A6J3EKF7
names: Function
names: Similarity
messages: Belongs to the SAP18 family.
messages: Involved in the tethering of the SIN3 complex to core histone proteins.

219594:OGFRL1
gene id: 219594:OGFRL1
uniprot id: A0A6J3CQS0
uniprot id: A0A6J3CRH0
names: Similarity
messages: Belongs to the opioid growth factor receptor family.

219594:LOC116499751
gene id: 219594:LOC116499751
uniprot id: A0A6J3E9U3
names: Similarity
names: Subunit
messages: Belongs to the avian keratin family.
messages: The avian keratins (F-ker, S-ker, C-ker and B-ker) are a complex mixture of very similar polypeptides.

219594:MFGE8
gene id: 219594:MFGE8
uniprot id: A0A6J3DKP1
uniprot id: A0A6J3DP80
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:LOC116497943
gene id: 219594:LOC116497943
uniprot id: A0A6J3E727
names: Subcellular Location Annotation
messages: Membrane

219594:PDE2A
gene id: 219594:PDE2A
uniprot id: A0A6J3EH44
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

219594:NAGLU
gene id: 219594:NAGLU
uniprot id: A0A6J3E9X3
names: Subcellular Location Annotation
messages: Lysosome

219594:PIGV
gene id: 219594:PIGV
uniprot id: A0A6J3E3J8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PIGV family.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mannosyltransferase involved in glycosylphosphatidylinositol-anchor biosynthesis.
messages: Membrane

219594:BMT2
gene id: 219594:BMT2
uniprot id: A0A6J3EK15
names: Function
names: Similarity
names: Subunit
messages: Belongs to the BMT2 family.
messages: Interacts with the GATOR1 complex; interaction is disrupted when BMT2/SAMTOR binds S-adenosyl-L-methionine. Interacts with the KICSTOR complex; interaction is disrupted when BMT2/SAMTOR binds S-adenosyl-L-methionine.
messages: S-adenosyl-L-methionine-binding protein that acts as an inhibitor of mTORC1 signaling via interaction with the GATOR1 and KICSTOR complexes. Acts as a sensor of S-adenosyl-L-methionine to signal methionine sufficiency to mTORC1: in presence of methionine, binds S-adenosyl-L-methionine, leading to disrupt interaction with the GATOR1 and KICSTOR complexes and promote mTORC1 signaling. Upon methionine starvation, S-adenosyl-L-methionine levels are reduced, thereby promoting the association with GATOR1 and KICSTOR, leading to inhibit mTORC1 signaling. Probably also acts as a S-adenosyl-L-methionine-dependent methyltransferase.

219594:C7
gene id: 219594:C7
uniprot id: A0A6J3EFX9
uniprot id: A0A6J3EL59
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complement C6/C7/C8/C9 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

219594:EAF2
gene id: 219594:EAF2
uniprot id: A0A6J3D453
names: Similarity
messages: Belongs to the EAF family.

219594:AGPS
gene id: 219594:AGPS
uniprot id: A0A6J3D8Y2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FAD-binding oxidoreductase/transferase type 4 family.
messages: Catalyzes the exchange of an acyl for a long-chain alkyl group and the formation of the ether bond in the biosynthesis of ether phospholipids.
messages: Homodimer.
messages: Peroxisome

219594:LOC116498674
gene id: 219594:LOC116498674
uniprot id: A0A6J3EC28
names: Similarity
messages: Belongs to the peptidase A1 family.

219594:EDIL3
gene id: 219594:EDIL3
uniprot id: A0A6J3EGU6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:TMEM251
gene id: 219594:TMEM251
uniprot id: A0A6J3D1U5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LYSET family.
messages: Membrane

219594:LOC116494383
gene id: 219594:LOC116494383
uniprot id: A0A6J3DKY3
uniprot id: A0A6J3DQ66
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

219594:LOC116489505
gene id: 219594:LOC116489505
uniprot id: A0A6J3D049
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

219594:RFC4
gene id: 219594:RFC4
uniprot id: A0A6J3DJV5
names: Similarity
messages: Belongs to the activator 1 small subunits family.

219594:TNNT2
gene id: 219594:TNNT2
uniprot id: A0A6J3E627
uniprot id: A0A6J3EAK4
uniprot id: A0A6J3EB63
names: Function
names: Similarity
messages: Belongs to the troponin T family.
messages: Troponin T is the tropomyosin-binding subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity.

219594:PTGDR
gene id: 219594:PTGDR
uniprot id: A0A6J3D3V8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

219594:LEF1
gene id: 219594:LEF1
uniprot id: A0A6J3CWG2
uniprot id: A0A6J3CZ08
uniprot id: A0A6J3D195
uniprot id: A0A6J3D2E4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TCF/LEF family.
messages: Nucleus

219594:CDH6
gene id: 219594:CDH6
uniprot id: A0A6J3CJG7
names: Function
names: Subcellular Location Annotation
messages: Cadherins are calcium-dependent cell adhesion proteins.
messages: Cell membrane

219594:USP20
gene id: 219594:USP20
uniprot id: A0A6J3E496
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C19 family. USP20/USP33 subfamily.
messages: centrosome
messages: perinuclear region

219594:PARP3
gene id: 219594:PARP3
uniprot id: A0A6J3DHI0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ARTD/PARP family.
messages: Nucleus

219594:KLC4
gene id: 219594:KLC4
uniprot id: A0A6J3CN45
uniprot id: A0A6J3CQR4
uniprot id: A0A6J3CT34
uniprot id: A0A6J3CU69
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the kinesin light chain family.
messages: Kinesin is a microtubule-associated force-producing protein that play a role in organelle transport.
messages: Oligomeric complex composed of two heavy chains and two light chains.
messages: cytoskeleton

219594:MED10
gene id: 219594:MED10
uniprot id: A0A6J3CF31
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 10 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex.
messages: Nucleus

219594:ST3GAL5
gene id: 219594:ST3GAL5
uniprot id: A0A6J3CXM0
uniprot id: A0A6J3CZY5
uniprot id: A0A6J3D125
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

219594:ATP6V1C1
gene id: 219594:ATP6V1C1
uniprot id: A0A6J3CGL4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the V-ATPase C subunit family.
messages: Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment. Subunit C is necessary for the assembly of the catalytic sector of the enzyme and is likely to have a specific function in its catalytic activity.
messages: V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex. The V1 complex consists of three catalytic AB heterodimers that form a heterohexamer, three peripheral stalks each consisting of EG heterodimers, one central rotor including subunits D and F, and the regulatory subunits C and H. The proton translocation complex V0 consists of the proton transport subunit a, a ring of proteolipid subunits c9c'', rotary subunit d, subunits e and f, and two accessory subunits.

219594:TOB2
gene id: 219594:TOB2
uniprot id: A0A6J3EJV3
names: Similarity
messages: Belongs to the BTG family.

219594:MED24
gene id: 219594:MED24
uniprot id: A0A6J3EBW7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Mediator complex subunit 24 family.
messages: Nucleus

219594:LOC116499096
gene id: 219594:LOC116499096
uniprot id: A0A6J3EE59
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.

219594:ARF6
gene id: 219594:ARF6
uniprot id: A0A6J3D665
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Arf family.
messages: Cell membrane
messages: Cleavage furrow
messages: Endosome membrane
messages: Midbody ring
messages: Recycling endosome membrane
messages: filopodium membrane
messages: ruffle

219594:ADAM10
gene id: 219594:ADAM10
uniprot id: A0A6J3DLK7
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:TMTC4
gene id: 219594:TMTC4
uniprot id: A0A6J3CML4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMTC family.
messages: Endoplasmic reticulum
messages: Membrane

219594:RNPEP
gene id: 219594:RNPEP
uniprot id: A0A6J3E9X7
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M1 family.
messages: Binds 1 zinc ion per subunit.

219594:CASTOR2
gene id: 219594:CASTOR2
uniprot id: A0A6J3E3X7
names: Similarity
messages: Belongs to the GATS family.

219594:STX17
gene id: 219594:STX17
uniprot id: A0A6J3CIJ6
names: Similarity
messages: Belongs to the syntaxin family.

219594:LOC116496139
gene id: 219594:LOC116496139
uniprot id: A0A6J3DZA1
names: Similarity
messages: Belongs to the sulfatase family.

219594:RIC8A
gene id: 219594:RIC8A
uniprot id: A0A6J3D1S3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the synembryn family.
messages: Cytoplasm
messages: Guanine nucleotide exchange factor (GEF), which can activate some, but not all, G-alpha proteins by exchanging bound GDP for free GTP.
messages: Interacts with some GDP-bound G alpha proteins. Does not interact with G-alpha proteins when they are in complex with subunits beta and gamma.

219594:SLC45A1
gene id: 219594:SLC45A1
uniprot id: A0A6J3E131
uniprot id: A0A6J3E2F7
names: Subcellular Location Annotation
messages: Membrane

219594:NAA30
gene id: 219594:NAA30
uniprot id: A0A6J3D433
names: Similarity
messages: Belongs to the acetyltransferase family. MAK3 subfamily.

219594:RPLP2
gene id: 219594:RPLP2
uniprot id: A0A6J3D7H0
names: Function
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein P1/P2 family.
messages: Plays an important role in the elongation step of protein synthesis.

219594:EPHB6
gene id: 219594:EPHB6
uniprot id: A0A6J3EJS1
uniprot id: A0A6J3EJT3
names: Subcellular Location Annotation
messages: Membrane

219594:PKP2
gene id: 219594:PKP2
uniprot id: A0A6J3D498
names: Similarity
messages: Belongs to the beta-catenin family.

219594:TCTEX1D2
gene id: 219594:TCTEX1D2
uniprot id: A0A6J3DC53
names: Similarity
messages: Belongs to the dynein light chain Tctex-type family.

219594:LRRC8B
gene id: 219594:LRRC8B
uniprot id: A0A6J3DEM1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LRRC8 family.
messages: Cell membrane
messages: Membrane

219594:TBCCD1
gene id: 219594:TBCCD1
uniprot id: A0A6J3DF18
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TBCC family.
messages: centrosome
messages: spindle pole

219594:SLC35F6
gene id: 219594:SLC35F6
uniprot id: A0A6J3CQM6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SLC35F solute transporter family.
messages: Interacts with SLC25A5.
messages: May play a role as a nucleotide-sugar transporter.
messages: Membrane
messages: Mitochondrion

219594:PPP3CC
gene id: 219594:PPP3CC
uniprot id: A0A6J3EA38
uniprot id: A0A6J3EFE9
names: Similarity
messages: Belongs to the PPP phosphatase family. PP-2B subfamily.

219594:MET
gene id: 219594:MET
uniprot id: A0A6J3CLI9
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

219594:PSMG2
gene id: 219594:PSMG2
uniprot id: A0A6J3CGP9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PSMG2 family.
messages: Chaperone protein which promotes assembly of the 20S proteasome as part of a heterodimer with PSMG1.
messages: Forms a heterodimer with PSMG1.

219594:UPK1B
gene id: 219594:UPK1B
uniprot id: A0A6J3E814
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

219594:MIGA2
gene id: 219594:MIGA2
uniprot id: A0A6J3DX03
uniprot id: A0A6J3E162
uniprot id: A0A6J3E1Z1
names: Similarity
messages: Belongs to the mitoguardin family.

219594:FAM168A
gene id: 219594:FAM168A
uniprot id: A0A6J3D597
names: Similarity
messages: Belongs to the FAM168 family.

219594:SLCO4A1
gene id: 219594:SLCO4A1
uniprot id: A0A6J3DY02
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the organo anion transporter (TC 2.A.60) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Secreted

219594:LOC116489648
gene id: 219594:LOC116489648
uniprot id: A0A6J3CYD3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2A family.
messages: Chromosome
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

219594:PROK1
gene id: 219594:PROK1
uniprot id: A0A6J3EAM7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AVIT (prokineticin) family.
messages: Secreted

219594:DDX59
gene id: 219594:DDX59
uniprot id: A0A6J3DB84
names: Similarity
messages: Belongs to the DEAD box helicase family. DDX59 subfamily.

219594:TRIQK
gene id: 219594:TRIQK
uniprot id: A0A6J3CNP1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRIQK family.
messages: Endoplasmic reticulum membrane
messages: Membrane

219594:NGFR
gene id: 219594:NGFR
uniprot id: A0A6J3E600
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:LOC116486698
gene id: 219594:LOC116486698
uniprot id: A0A6J3CNS0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic ribosomal protein eS7 family.
messages: centrosome

219594:RBPMS2
gene id: 219594:RBPMS2
uniprot id: A0A6J3DHL2
names: Subcellular Location Annotation
messages: Cytoplasm

219594:ARRB1
gene id: 219594:ARRB1
uniprot id: A0A6J3ENE2
names: Similarity
messages: Belongs to the arrestin family.

219594:KIF12
gene id: 219594:KIF12
uniprot id: A0A6J3E5C1
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

219594:EFNB1
gene id: 219594:EFNB1
uniprot id: A0A6J3DNA4
uniprot id: A0A6J3DS57
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ephrin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

219594:LOC116491118
gene id: 219594:LOC116491118
uniprot id: A0A6J3D8H0
uniprot id: A0A6J3D8Z5
names: Similarity
messages: Belongs to the hexokinase family.

219594:LDB3
gene id: 219594:LDB3
uniprot id: A0A6J3D783
uniprot id: A0A6J3D9W9
uniprot id: A0A6J3DAL6
uniprot id: A0A6J3DCS2
uniprot id: A0A6J3DD62
names: Subcellular Location Annotation
messages: Z line

219594:IPO5
gene id: 219594:IPO5
uniprot id: A0A6J3DC12
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

219594:LOC116499494
gene id: 219594:LOC116499494
uniprot id: A0A6J3EDL1
names: Similarity
names: Subunit
messages: Belongs to the avian keratin family.
messages: The avian keratins (F-ker, S-ker, C-ker and B-ker) are a complex mixture of very similar polypeptides.

219594:CASP9
gene id: 219594:CASP9
uniprot id: A0A6J3E1A9
uniprot id: A0A6J3E5J7
names: Similarity
messages: Belongs to the peptidase C14A family.

219594:FOXN2
gene id: 219594:FOXN2
uniprot id: A0A6J3CTH2
uniprot id: A0A6J3CVR0
names: Subcellular Location Annotation
messages: Nucleus

219594:TMEM200B
gene id: 219594:TMEM200B
uniprot id: A0A6J3E3H3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM200 family.
messages: Membrane

219594:METTL16
gene id: 219594:METTL16
uniprot id: A0A6J3EP45
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily. METTL16/RlmF family.
messages: RNA N6-methyltransferase that methylates adenosine residues at the N(6) position of a subset of RNAs and is involved in S-adenosyl-L-methionine homeostasis by regulating expression of MAT2A transcripts. Able to N6-methylate a subset of mRNAs and U6 small nuclear RNAs (U6 snRNAs). In contrast to the METTL3-METTL14 heterodimer, only able to methylate a limited number of RNAs: requires both a 5'UACAGAGAA-3' nonamer sequence and a specific RNA structure.

219594:GPR3
gene id: 219594:GPR3
uniprot id: A0A6J3E8B8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

219594:SNPH
gene id: 219594:SNPH
uniprot id: A0A6J3DX10
names: Subcellular Location Annotation
messages: Membrane

219594:CALR3
gene id: 219594:CALR3
uniprot id: A0A6J3E804
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calreticulin family.
messages: Endoplasmic reticulum lumen

219594:MYF6
gene id: 219594:MYF6
uniprot id: A0A6J3EIE7
names: Subcellular Location Annotation
messages: Nucleus

219594:CP
gene id: 219594:CP
uniprot id: A0A6J3DBH6
names: Similarity
messages: Belongs to the multicopper oxidase family.

219594:TMEM121B
gene id: 219594:TMEM121B
uniprot id: A0A6J3CSH4
names: Similarity
messages: Belongs to the TMEM121 family.

219594:UTP15
gene id: 219594:UTP15
uniprot id: A0A6J3EKL7
names: Subcellular Location Annotation
messages: nucleolus

219594:LOC116498361
gene id: 219594:LOC116498361
uniprot id: A0A6J3E5P7
names: Similarity
names: Subunit
messages: Belongs to the avian keratin family.
messages: The avian keratins (F-ker, S-ker, C-ker and B-ker) are a complex mixture of very similar polypeptides.

219594:BCL7B
gene id: 219594:BCL7B
uniprot id: A0A6J3E159
uniprot id: A0A6J3E3W8
names: Similarity
messages: Belongs to the BCL7 family.

219594:LOC116499507
gene id: 219594:LOC116499507
uniprot id: A0A6J3E8X1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 30 family.
messages: Lysosome membrane

219594:PLLP
gene id: 219594:PLLP
uniprot id: A0A6J3DRB1
names: Subcellular Location Annotation
messages: Membrane

219594:IL12A
gene id: 219594:IL12A
uniprot id: A0A6J3DCI9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IL-6 superfamily.
messages: Heterodimer with IL12B; disulfide-linked. The heterodimer is known as interleukin IL-12.
messages: Secreted

219594:PTGES
gene id: 219594:PTGES
uniprot id: A0A6J3DY36
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MAPEG family.
messages: Membrane

219594:LOC116495850
gene id: 219594:LOC116495850
uniprot id: A0A6J3DUS5
names: Subcellular Location Annotation
messages: Nucleus

219594:LOC116499485
gene id: 219594:LOC116499485
uniprot id: A0A6J3EDZ5
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily.

219594:HAT1
gene id: 219594:HAT1
uniprot id: A0A6J3DAA3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAT1 family.
messages: Catalytic subunit of the type B histone acetyltransferase (HAT) complex, composed of RBBP7 and HAT1. Interacts with histones H4 and H2A.
messages: Histone acetyltransferase that plays a role in different biological processes including cell cycle progression, glucose metabolism, histone production or DNA damage repair. Coordinates histone production and acetylation via H4 promoter binding. Acetylates histone H4 at 'Lys-5' (H4K5ac) and 'Lys-12' (H4K12ac) and, to a lesser extent, histone H2A at 'Lys-5' (H2AK5ac).

219594:UBP1
gene id: 219594:UBP1
uniprot id: A0A6J3CH91
uniprot id: A0A6J3CJ68
uniprot id: A0A6J3CKW3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the grh/CP2 family. CP2 subfamily.
messages: Nucleus

219594:ZDHHC21
gene id: 219594:ZDHHC21
uniprot id: A0A6J3ED01
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

219594:HSPA4
gene id: 219594:HSPA4
uniprot id: A0A6J3DSJ1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the heat shock protein 70 family.
messages: Cytoplasm
messages: Interacts with TJP1/ZO-1.

219594:LOC116486723
gene id: 219594:LOC116486723
uniprot id: A0A6J3CKR1
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thrombospondin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular space

219594:SCUBE3
gene id: 219594:SCUBE3
uniprot id: A0A6J3ECS5
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

219594:CD2
gene id: 219594:CD2
uniprot id: A0A6J3DSX5
names: Subcellular Location Annotation
messages: Membrane

219594:EML6
gene id: 219594:EML6
uniprot id: A0A6J3CMR3
uniprot id: A0A6J3CNU0
names: Function
names: Similarity
messages: Belongs to the WD repeat EMAP family.
messages: May modify the assembly dynamics of microtubules, such that microtubules are slightly longer, but more dynamic.

219594:NUP85
gene id: 219594:NUP85
uniprot id: A0A6J3E2N1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the nucleoporin Nup85 family.
messages: Component of the nuclear pore complex (NPC).
messages: Functions as a component of the nuclear pore complex (NPC).
messages: Nucleus membrane
messages: nuclear pore complex

219594:RAPGEF6
gene id: 219594:RAPGEF6
uniprot id: A0A6J3DMS3
uniprot id: A0A6J3DS41
names: Similarity
messages: Belongs to the RAPGEF2 family.

219594:LOC116495396
gene id: 219594:LOC116495396
uniprot id: A0A6J3DUU0
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

219594:CD320
gene id: 219594:CD320
uniprot id: A0A6J3ECQ0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:SZRD1
gene id: 219594:SZRD1
uniprot id: A0A6J3E1Q3
uniprot id: A0A6J3E5Y6
names: Similarity
messages: Belongs to the SZRD1 family.

219594:APPL2
gene id: 219594:APPL2
uniprot id: A0A6J3EQ44
uniprot id: A0A6J3EQ51
names: Subcellular Location Annotation
messages: Early endosome membrane
messages: Endosome membrane
messages: Membrane
messages: Nucleus
messages: phagosome
messages: ruffle

219594:LCTL
gene id: 219594:LCTL
uniprot id: A0A6J3DHF4
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

219594:VPS11
gene id: 219594:VPS11
uniprot id: A0A6J3E403
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VPS11 family.
messages: Cytoplasmic vesicle
messages: Early endosome
messages: Late endosome membrane
messages: Lysosome membrane
messages: Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes.
messages: autophagosome
messages: clathrin-coated vesicle

219594:LOC116499591
gene id: 219594:LOC116499591
uniprot id: A0A6J3EE97
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the selenium-binding protein family.
messages: Catalyzes the oxidation of methanethiol, an organosulfur compound known to be produced in substantial amounts by gut bacteria. Selenium-binding protein which may be involved in the sensing of reactive xenobiotics in the cytoplasm. May be involved in intra-Golgi protein transport.
messages: Membrane
messages: Nucleus
messages: cytosol

219594:SUPT4H1
gene id: 219594:SUPT4H1
uniprot id: A0A6J3E0X5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPT4 family.
messages: Component of the DRB sensitivity-inducing factor complex (DSIF complex), which regulates transcription elongation by RNA polymerase II.
messages: Nucleus

219594:LOC116500621
gene id: 219594:LOC116500621
uniprot id: A0A6J3EEI6
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.

219594:CLRN3
gene id: 219594:CLRN3
uniprot id: A0A6J3D844
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the clarin family.
messages: Membrane

219594:SLC25A30
gene id: 219594:SLC25A30
uniprot id: A0A6J3DM37
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

219594:BEND6
gene id: 219594:BEND6
uniprot id: A0A6J3CM30
uniprot id: A0A6J3CNU1
names: Subcellular Location Annotation
messages: Nucleus

219594:LOC116485600
gene id: 219594:LOC116485600
uniprot id: A0A6J3CHT8
names: Subcellular Location Annotation
messages: Membrane

219594:PGP
gene id: 219594:PGP
uniprot id: A0A6J3DQ76
names: Cofactor
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.
messages: Divalent metal ions. Mg(2+) is the most effective.

219594:SET
gene id: 219594:SET
uniprot id: A0A6J3DZC7
names: Similarity
messages: Belongs to the nucleosome assembly protein (NAP) family.

219594:CDC20B
gene id: 219594:CDC20B
uniprot id: A0A6J3EJG0
names: Similarity
messages: Belongs to the WD repeat CDC20/Fizzy family.

219594:TMEM59
gene id: 219594:TMEM59
uniprot id: A0A6J3DCI7
uniprot id: A0A6J3DFL5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM59 family.
messages: Golgi apparatus membrane
messages: Membrane

219594:LOC116494404
gene id: 219594:LOC116494404
uniprot id: A0A6J3DSC7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sestrin family.
messages: Cytoplasm

219594:FAM102B
gene id: 219594:FAM102B
uniprot id: A0A6J3DF06
names: Similarity
messages: Belongs to the EEIG family.

219594:QTRT2
gene id: 219594:QTRT2
uniprot id: A0A6J3ELI2
uniprot id: A0A6J3ELI8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family. QTRT2 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Heterodimer of a catalytic subunit QTRT1 and an accessory subunit QTRT2.
messages: Mitochondrion outer membrane
messages: Non-catalytic subunit of the queuine tRNA-ribosyltransferase (TGT) that catalyzes the base-exchange of a guanine (G) residue with queuine (Q) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).

219594:EIF2B1
gene id: 219594:EIF2B1
uniprot id: A0A6J3DZJ9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eIF-2B alpha/beta/delta subunits family.
messages: Catalyzes the exchange of eukaryotic initiation factor 2-bound GDP for GTP.
messages: Complex of five different subunits; alpha, beta, gamma, delta and epsilon.

219594:HADHA
gene id: 219594:HADHA
uniprot id: A0A6J3CSH8
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.
messages: In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family.

219594:TENM4
gene id: 219594:TENM4
uniprot id: A0A6J3DL17
uniprot id: A0A6J3DL33
uniprot id: A0A6J3DNI8
uniprot id: A0A6J3DNJ8
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tenascin family. Teneurin subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

219594:LOC116485337
gene id: 219594:LOC116485337
uniprot id: A0A6J3CGD5
names: Similarity
names: Subunit
messages: Belongs to the avian keratin family.
messages: The avian keratins (F-ker, S-ker, C-ker and B-ker) are a complex mixture of very similar polypeptides.

219594:CD47
gene id: 219594:CD47
uniprot id: A0A6J3CRK3
uniprot id: A0A6J3CRL8
uniprot id: A0A6J3CTX1
uniprot id: A0A6J3CXQ8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

219594:DMRT2
gene id: 219594:DMRT2
uniprot id: A0A6J3EL54
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DMRT family.
messages: Nucleus

219594:TPH2
gene id: 219594:TPH2
uniprot id: A0A6J3DTG4
names: Similarity
messages: Belongs to the biopterin-dependent aromatic amino acid hydroxylase family.

219594:LIG3
gene id: 219594:LIG3
uniprot id: A0A6J3E0N0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP-dependent DNA ligase family.
messages: Nucleus

219594:PWWP3A
gene id: 219594:PWWP3A
uniprot id: A0A6J3EBB7
names: Similarity
messages: Belongs to the PWWP3A family.

219594:CCKAR
gene id: 219594:CCKAR
uniprot id: A0A6J3CW05
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for cholecystokinin. Mediates pancreatic growth and enzyme secretion, smooth muscle contraction of the gall bladder and stomach. Has a 1000-fold higher affinity for CCK rather than for gastrin. It modulates feeding and dopamine-induced behavior in the central and peripheral nervous system. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system.

219594:CSRNP1
gene id: 219594:CSRNP1
uniprot id: A0A6J3CLK5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AXUD1 family.
messages: Nucleus

219594:EIF3M
gene id: 219594:EIF3M
uniprot id: A0A6J3D663
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CSN7/EIF3M family. CSN7 subfamily.
messages: Belongs to the eIF-3 subunit M family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is composed of 13 subunits: EIF3A, EIF3B, EIF3C, EIF3D, EIF3E, EIF3F, EIF3G, EIF3H, EIF3I, EIF3J, EIF3K, EIF3L and EIF3M.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
messages: Cytoplasm

219594:HAUS3
gene id: 219594:HAUS3
uniprot id: A0A6J3CXY2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HAUS3 family.
messages: spindle

219594:BDKRB1
gene id: 219594:BDKRB1
uniprot id: A0A6J3D3J2
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: This is a receptor for bradykinin. Could be a factor in chronic pain and inflammation.

219594:EIF4E
gene id: 219594:EIF4E
uniprot id: A0A6J3CYN0
names: Similarity
messages: Belongs to the eukaryotic initiation factor 4E family.

219594:HSP90AA1
gene id: 219594:HSP90AA1
uniprot id: A0A6J3D2E5
names: Similarity
messages: Belongs to the heat shock protein 90 family.

219594:RORC
gene id: 219594:RORC
uniprot id: A0A6J3EFY1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

219594:KCNH1
gene id: 219594:KCNH1
uniprot id: A0A6J3CW51
names: Subcellular Location Annotation
messages: Membrane

219594:ENY2
gene id: 219594:ENY2
uniprot id: A0A6J3CM73
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ENY2 family.
messages: Component of the nuclear pore complex (NPC)-associated TREX-2 complex (transcription and export complex 2). Component of the SAGA transcription coactivator-HAT complex. Within the SAGA complex, participates to a subcomplex of SAGA called the DUB module (deubiquitination module).
messages: Involved in mRNA export coupled transcription activation by association with both the TREX-2 and the SAGA complexes. The transcription regulatory histone acetylation (HAT) complex SAGA is a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates to a subcomplex that specifically deubiquitinates histones. The SAGA complex is recruited to specific gene promoters by activators, where it is required for transcription. The TREX-2 complex functions in docking export-competent ribonucleoprotein particles (mRNPs) to the nuclear entrance of the nuclear pore complex (nuclear basket). TREX-2 participates in mRNA export and accurate chromatin positioning in the nucleus by tethering genes to the nuclear periphery.
messages: nucleoplasm

219594:LOC116501292
gene id: 219594:LOC116501292
uniprot id: A0A6J3EG42
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:NSMCE2
gene id: 219594:NSMCE2
uniprot id: A0A6J3CMD4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NSE2 family.
messages: Nucleus

219594:FABP7
gene id: 219594:FABP7
uniprot id: A0A6J3CNF3
names: Similarity
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.

219594:FIP1L1
gene id: 219594:FIP1L1
uniprot id: A0A6J3CS18
uniprot id: A0A6J3CUC7
uniprot id: A0A6J3CUV1
uniprot id: A0A6J3CX53
uniprot id: A0A6J3CY96
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FIP1 family.
messages: Nucleus

219594:NTNG2
gene id: 219594:NTNG2
uniprot id: A0A6J3DZ35
uniprot id: A0A6J3E3F1
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:GCLC
gene id: 219594:GCLC
uniprot id: A0A6J3CQI4
names: Similarity
messages: Belongs to the glutamate--cysteine ligase type 3 family.

219594:FANCM
gene id: 219594:FANCM
uniprot id: A0A6J3D3B6
names: Similarity
messages: Belongs to the DEAD box helicase family. DEAH subfamily. FANCM sub-subfamily.

219594:STT3B
gene id: 219594:STT3B
uniprot id: A0A6J3CGL9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STT3 family.
messages: Membrane

219594:MED27
gene id: 219594:MED27
uniprot id: A0A6J3E3P8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Mediator complex subunit 27 family.
messages: Nucleus

219594:VPS54
gene id: 219594:VPS54
uniprot id: A0A6J3CR13
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VPS54 family.
messages: trans-Golgi network

219594:ULK3
gene id: 219594:ULK3
uniprot id: A0A6J3DH24
uniprot id: A0A6J3DJP6
uniprot id: A0A6J3DL59
uniprot id: A0A6J3DN55
names: Similarity
messages: Belongs to the protein kinase superfamily.

219594:PHYHIP
gene id: 219594:PHYHIP
uniprot id: A0A6J3EA48
names: Similarity
messages: Belongs to the PHYHIP family.

219594:BRK1
gene id: 219594:BRK1
uniprot id: A0A6J3DFE8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BRK1 family.
messages: cytoskeleton

219594:PDE3B
gene id: 219594:PDE3B
uniprot id: A0A6J3D220
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

219594:CAPZB
gene id: 219594:CAPZB
uniprot id: A0A6J3E102
uniprot id: A0A6J3E579
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the F-actin-capping protein beta subunit family.
messages: F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.
messages: Heterodimer of an alpha and a beta subunit.
messages: cytoskeleton

219594:GAS8
gene id: 219594:GAS8
uniprot id: A0A6J3DQF8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DRC4 family.
messages: flagellum
messages: flagellum axoneme

219594:LOC116488194
gene id: 219594:LOC116488194
uniprot id: A0A6J3CW30
uniprot id: A0A6J3CX72
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

219594:LOC116500310
gene id: 219594:LOC116500310
uniprot id: A0A6J3EGH7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

219594:IGF1
gene id: 219594:IGF1
uniprot id: A0A6J3DNQ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the insulin family.
messages: Secreted

219594:LOC116486404
gene id: 219594:LOC116486404
uniprot id: A0A6J3CNR9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dienelactone hydrolase family.
messages: cytosol

219594:LCLAT1
gene id: 219594:LCLAT1
uniprot id: A0A6J3CRM2
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.

219594:PTGES2
gene id: 219594:PTGES2
uniprot id: A0A6J3E319
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GST superfamily.
messages: Membrane

219594:NFIC
gene id: 219594:NFIC
uniprot id: A0A6J3E786
uniprot id: A0A6J3E8S5
uniprot id: A0A6J3EBU7
uniprot id: A0A6J3ECB4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CTF/NF-I family.
messages: Binds DNA as a homodimer.
messages: Nucleus
messages: Recognizes and binds the palindromic sequence 5'-TTGGCNNNNNGCCAA-3' present in viral and cellular promoters and in the origin of replication of adenovirus type 2. These proteins are individually capable of activating transcription and replication.

219594:ZC2HC1C
gene id: 219594:ZC2HC1C
uniprot id: A0A6J3CXU2
names: Similarity
messages: Belongs to the ZC2HC1 family.

219594:MED15
gene id: 219594:MED15
uniprot id: A0A6J3DY31
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 15 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex.
messages: Nucleus

219594:HSPB2
gene id: 219594:HSPB2
uniprot id: A0A6J3E894
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

219594:KIF15
gene id: 219594:KIF15
uniprot id: A0A6J3CL00
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. KIN-12 subfamily.
messages: spindle

219594:INHBA
gene id: 219594:INHBA
uniprot id: A0A6J3CLG9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TGF-beta family.
messages: Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition. Inhibins appear to oppose the functions of activins.
messages: Secreted

219594:TMEM263
gene id: 219594:TMEM263
uniprot id: A0A6J3EPA3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM263 family.
messages: Membrane

219594:P3H1
gene id: 219594:P3H1
uniprot id: A0A6J3E747
names: Similarity
messages: Belongs to the leprecan family.

219594:TWSG1
gene id: 219594:TWSG1
uniprot id: A0A6J3CM70
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the twisted gastrulation protein family.
messages: Secreted

219594:TMEM123
gene id: 219594:TMEM123
uniprot id: A0A6J3D7H5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CD164 family.
messages: Membrane

219594:EOMES
gene id: 219594:EOMES
uniprot id: A0A6J3CL90
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

219594:CIT
gene id: 219594:CIT
uniprot id: A0A6J3DV47
uniprot id: A0A6J3DV52
uniprot id: A0A6J3DWZ2
uniprot id: A0A6J3DZA2
uniprot id: A0A6J3E010
uniprot id: A0A6J3E019
uniprot id: A0A6J3E138
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family.
messages: Cytoplasm
messages: Plays a role in cytokinesis. Displays serine/threonine protein kinase activity.

219594:PTX3
gene id: 219594:PTX3
uniprot id: A0A6J3DGL3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:CCT3
gene id: 219594:CCT3
uniprot id: A0A6J3EB99
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TCP-1 chaperonin family.
messages: Cytoplasm

219594:SEMA5A
gene id: 219594:SEMA5A
uniprot id: A0A6J3CCD3
uniprot id: A0A6J3CF10
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:TSC22D2
gene id: 219594:TSC22D2
uniprot id: A0A6J3DE03
uniprot id: A0A6J3DF50
names: Similarity
messages: Belongs to the TSC-22/Dip/Bun family.

219594:LOC116493505
gene id: 219594:LOC116493505
uniprot id: A0A6J3DHB0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome P450 family.
messages: Cytochromes P450 are a group of heme-thiolate monooxygenases. They oxidize a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Microsome membrane

219594:IL21
gene id: 219594:IL21
uniprot id: A0A6J3CY09
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IL-15/IL-21 family.
messages: Secreted

219594:APOOL
gene id: 219594:APOOL
uniprot id: A0A6J3DSY9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the apolipoprotein O/MICOS complex subunit Mic27 family.
messages: Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane.
messages: Component of the mitochondrial contact site and cristae organizing system (MICOS) complex.
messages: Mitochondrion inner membrane

219594:PHKB
gene id: 219594:PHKB
uniprot id: A0A6J3DII4
uniprot id: A0A6J3DII9
uniprot id: A0A6J3DMN1
uniprot id: A0A6J3DPN1
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Although the final Cys may be farnesylated, the terminal tripeptide is probably not removed, and the C-terminus is not methylated.
messages: Belongs to the phosphorylase b kinase regulatory chain family.
messages: Cell membrane
messages: Membrane
messages: Phosphorylase b kinase catalyzes the phosphorylation of serine in certain substrates, including troponin I.

219594:NFIB
gene id: 219594:NFIB
uniprot id: A0A6J3EDZ8
uniprot id: A0A6J3EFE2
uniprot id: A0A6J3EFE7
uniprot id: A0A6J3EIV7
uniprot id: A0A6J3EJ81
uniprot id: A0A6J3EJ83
uniprot id: A0A6J3EKR1
uniprot id: A0A6J3EKR6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CTF/NF-I family.
messages: Binds DNA as a homodimer.
messages: Nucleus
messages: Recognizes and binds the palindromic sequence 5'-TTGGCNNNNNGCCAA-3' present in viral and cellular promoters and in the origin of replication of adenovirus type 2. These proteins are individually capable of activating transcription and replication.

219594:TYSND1
gene id: 219594:TYSND1
uniprot id: A0A6J3D971
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S1B family.
messages: Peroxisomal protease that mediates both the removal of the leader peptide from proteins containing a PTS2 target sequence and processes several PTS1-containing proteins. Catalyzes the processing of PTS1-proteins involved in the peroxisomal beta-oxidation of fatty acids.
messages: Peroxisome
messages: The full-lengh TYSND1 is the active the proteolytic processing of PTS1- and PTS2-proteins and in self-cleavage, and intermolecular self-cleavage of TYSND1 down-regulates its protease activity.

219594:TMEM233
gene id: 219594:TMEM233
uniprot id: A0A6J3DZL2
names: Similarity
messages: Belongs to the CD225/Dispanin family.

219594:AQR
gene id: 219594:AQR
uniprot id: A0A6J3D369
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CWF11 family.
messages: Nucleus

219594:TADA2A
gene id: 219594:TADA2A
uniprot id: A0A6J3E1D8
names: Subcellular Location Annotation
messages: Nucleus

219594:CRYAB
gene id: 219594:CRYAB
uniprot id: A0A6J3E452
uniprot id: A0A6J3E715
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

219594:LOC116493572
gene id: 219594:LOC116493572
uniprot id: A0A6J3DLM5
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-dependent O-methyltransferase family.

219594:PDE11A
gene id: 219594:PDE11A
uniprot id: A0A6J3D6F7
uniprot id: A0A6J3D6Y7
uniprot id: A0A6J3D960
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

219594:LOC116493439
gene id: 219594:LOC116493439
uniprot id: A0A6J3DMH2
uniprot id: A0A6J3DN19
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adaptor complexes small subunit family.
messages: Cytoplasmic vesicle membrane
messages: Membrane
messages: Part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane and may be directly involved in trafficking to lysosomes. In concert with the BLOC-1 complex, AP-3 is required to target cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals.

219594:TXK
gene id: 219594:TXK
uniprot id: A0A6J3D115
names: Similarity
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.

219594:PDHX
gene id: 219594:PDHX
uniprot id: A0A6J3D113
uniprot id: A0A6J3D147
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 1 lipoyl cofactor covalently.
messages: Mitochondrion
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).

219594:GJA8
gene id: 219594:GJA8
uniprot id: A0A6J3EN36
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family. Alpha-type (group II) subfamily.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

219594:LOC116486083
gene id: 219594:LOC116486083
uniprot id: A0A6J3CFZ1
names: Similarity
messages: Belongs to the serpin family.

219594:TNFSF13B
gene id: 219594:TNFSF13B
uniprot id: A0A6J3EHI3
names: Similarity
messages: Belongs to the tumor necrosis factor family.

219594:MC5R
gene id: 219594:MC5R
uniprot id: A0A6J3CK50
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for MSH (alpha, beta and gamma) and ACTH. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. This receptor is a possible mediator of the immunomodulation properties of melanocortins.

219594:THYN1
gene id: 219594:THYN1
uniprot id: A0A6J3E274
names: Function
names: Subcellular Location Annotation
messages: Nucleus
messages: Specifically binds 5-hydroxymethylcytosine (5hmC), suggesting that it acts as a specific reader of 5hmC.

219594:MED8
gene id: 219594:MED8
uniprot id: A0A6J3DGR5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 8 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. May play a role as a target recruitment subunit in E3 ubiquitin-protein ligase complexes and thus in ubiquitination and subsequent proteasomal degradation of target proteins.
messages: Component of the Mediator complex.
messages: Nucleus

219594:HDAC8
gene id: 219594:HDAC8
uniprot id: A0A6J3DT74
names: Similarity
messages: Belongs to the histone deacetylase family. HD type 1 subfamily.

219594:LOC116485803
gene id: 219594:LOC116485803
uniprot id: A0A6J3CGY2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the somatotropin/prolactin family.
messages: Secreted

219594:IGFBP1
gene id: 219594:IGFBP1
uniprot id: A0A6J3CD76
names: Caution
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Binds equally well IGF1 and IGF2.
messages: IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors. Promotes cell migration.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

219594:MCM3
gene id: 219594:MCM3
uniprot id: A0A6J3CXX0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as component of the MCM2-7 complex (MCM complex) which is the replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity.
messages: Belongs to the MCM family.
messages: Chromosome
messages: Component of the MCM2-7 complex.
messages: Nucleus

219594:SGO2
gene id: 219594:SGO2
uniprot id: A0A6J3D9K1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the shugoshin family.
messages: centromere

219594:HOXA1
gene id: 219594:HOXA1
uniprot id: A0A6J3CL99
names: Subcellular Location Annotation
messages: Nucleus

219594:SELENOM
gene id: 219594:SELENOM
uniprot id: A0A6J3DYA6
names: Similarity
messages: Belongs to the selenoprotein M/F family.

219594:TGS1
gene id: 219594:TGS1
uniprot id: A0A6J3CNK4
names: Similarity
messages: Belongs to the methyltransferase superfamily. Trimethylguanosine synthase family.

219594:GLRX
gene id: 219594:GLRX
uniprot id: A0A6J3ELI1
names: Function
messages: Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins.

219594:GRIN3A
gene id: 219594:GRIN3A
uniprot id: A0A6J3EEX8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Receptor for glutamate that functions as a ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system.

219594:LOC116500176
gene id: 219594:LOC116500176
uniprot id: A0A6J3EHZ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the immunoglobulin superfamily. BTN/MOG family.
messages: Membrane

219594:DGKE
gene id: 219594:DGKE
uniprot id: A0A6J3E0K5
names: Similarity
messages: Belongs to the eukaryotic diacylglycerol kinase family.

219594:MCM9
gene id: 219594:MCM9
uniprot id: A0A6J3CQW5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MCM family.
messages: Nucleus

219594:F7
gene id: 219594:F7
uniprot id: A0A6J3EG70
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

219594:CLCN7
gene id: 219594:CLCN7
uniprot id: A0A6J3DT09
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chloride channel (TC 2.A.49) family.
messages: Membrane

219594:RCAN1
gene id: 219594:RCAN1
uniprot id: A0A6J3CQ15
uniprot id: A0A6J3CQR9
names: Similarity
messages: Belongs to the RCAN family.

219594:MYO9A
gene id: 219594:MYO9A
uniprot id: A0A6J3DGV8
uniprot id: A0A6J3DJI8
uniprot id: A0A6J3DKZ2
uniprot id: A0A6J3DMD9
uniprot id: A0A6J3DME4
uniprot id: A0A6J3DMZ2
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.

219594:LOC116493005
gene id: 219594:LOC116493005
uniprot id: A0A6J3DIR3
names: Similarity
messages: Belongs to the CAND family.

219594:LOC116497804
gene id: 219594:LOC116497804
uniprot id: A0A6J3E3E0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family.
messages: Membrane

219594:CHAC1
gene id: 219594:CHAC1
uniprot id: A0A6J3D4V7
names: Function
names: Similarity
messages: Belongs to the gamma-glutamylcyclotransferase family. ChaC subfamily.
messages: Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides.

219594:NDST4
gene id: 219594:NDST4
uniprot id: A0A6J3CV05
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 1 family. NDST subfamily.
messages: Membrane

219594:PPIP5K2
gene id: 219594:PPIP5K2
uniprot id: A0A6J3EFW0
uniprot id: A0A6J3EFW5
uniprot id: A0A6J3EHE1
uniprot id: A0A6J3EHE4
uniprot id: A0A6J3EL44
uniprot id: A0A6J3EL49
uniprot id: A0A6J3EML0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histidine acid phosphatase family. VIP1 subfamily.
messages: Bifunctional inositol kinase that acts in concert with the IP6K kinases to synthesize the diphosphate group-containing inositol pyrophosphates diphosphoinositol pentakisphosphate, PP-InsP5, and bis-diphosphoinositol tetrakisphosphate, (PP)2-InsP4. PP-InsP5 and (PP)2-InsP4, also respectively called InsP7 and InsP8, may regulate a variety of cellular processes, including apoptosis, vesicle trafficking, cytoskeletal dynamics, and exocytosis. Phosphorylates inositol hexakisphosphate (InsP6).
messages: cytosol

219594:LOC116498302
gene id: 219594:LOC116498302
uniprot id: A0A6J3E482
names: Similarity
names: Subunit
messages: Belongs to the avian keratin family.
messages: The avian keratins (F-ker, S-ker, C-ker and B-ker) are a complex mixture of very similar polypeptides.

219594:SYT2
gene id: 219594:SYT2
uniprot id: A0A6J3EBA5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptotagmin family.
messages: Binds 3 Ca(2+) ions per subunit. The ions are bound to the C2 domains.
messages: May have a regulatory role in the membrane interactions during trafficking of synaptic vesicles at the active zone of the synapse. It binds acidic phospholipids with a specificity that requires the presence of both an acidic head group and a diacyl backbone.
messages: synaptic vesicle membrane

219594:ABCC4
gene id: 219594:ABCC4
uniprot id: A0A6J3D9T0
uniprot id: A0A6J3DCE3
names: Subcellular Location Annotation
messages: Membrane

219594:SLC6A5
gene id: 219594:SLC6A5
uniprot id: A0A6J3CZG8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

219594:FGFR2
gene id: 219594:FGFR2
uniprot id: A0A6J3D6E4
uniprot id: A0A6J3D943
uniprot id: A0A6J3D948
uniprot id: A0A6J3D9P3
uniprot id: A0A6J3DBV8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. Fibroblast growth factor receptor subfamily.
messages: Cell membrane
messages: Membrane

219594:DMBX1
gene id: 219594:DMBX1
uniprot id: A0A6J3DDD5
uniprot id: A0A6J3DEF8
names: Subcellular Location Annotation
messages: Nucleus

219594:KCNE5
gene id: 219594:KCNE5
uniprot id: A0A6J3DRN1
names: Similarity
messages: Belongs to the potassium channel KCNE family.

219594:GAS6
gene id: 219594:GAS6
uniprot id: A0A6J3E225
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:LOC116486856
gene id: 219594:LOC116486856
uniprot id: A0A6J3CPJ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dienelactone hydrolase family.
messages: cytosol

219594:NUP210
gene id: 219594:NUP210
uniprot id: A0A6J3DKL3
names: Similarity
messages: Belongs to the NUP210 family.

219594:PPIP5K1
gene id: 219594:PPIP5K1
uniprot id: A0A6J3DG69
uniprot id: A0A6J3DG75
uniprot id: A0A6J3DIV9
uniprot id: A0A6J3DIW4
uniprot id: A0A6J3DK71
uniprot id: A0A6J3DLS2
uniprot id: A0A6J3DM88
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histidine acid phosphatase family. VIP1 subfamily.
messages: Bifunctional inositol kinase that acts in concert with the IP6K kinases to synthesize the diphosphate group-containing inositol pyrophosphates diphosphoinositol pentakisphosphate, PP-InsP5, and bis-diphosphoinositol tetrakisphosphate, (PP)2-InsP4. PP-InsP5 and (PP)2-InsP4, also respectively called InsP7 and InsP8, may regulate a variety of cellular processes, including apoptosis, vesicle trafficking, cytoskeletal dynamics, and exocytosis. Phosphorylates inositol hexakisphosphate (InsP6).
messages: cytosol

219594:TAF8
gene id: 219594:TAF8
uniprot id: A0A6J3EAB7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAF8 family.
messages: Nucleus

219594:CAPN5
gene id: 219594:CAPN5
uniprot id: A0A6J3DKH5
names: Similarity
messages: Belongs to the peptidase C2 family.

219594:EBNA1BP2
gene id: 219594:EBNA1BP2
uniprot id: A0A6J3DDK2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EBP2 family.
messages: Required for the processing of the 27S pre-rRNA.
messages: nucleolus

219594:KIF18A
gene id: 219594:KIF18A
uniprot id: A0A6J3D288
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

219594:SLC35A5
gene id: 219594:SLC35A5
uniprot id: A0A6J3EI66
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleotide-sugar transporter family. SLC35A subfamily.
messages: Golgi apparatus membrane
messages: Membrane

219594:FMNL2
gene id: 219594:FMNL2
uniprot id: A0A6J3D2F4
uniprot id: A0A6J3D2F9
uniprot id: A0A6J3D4V5
uniprot id: A0A6J3D4W0
uniprot id: A0A6J3D4W5
uniprot id: A0A6J3D587
uniprot id: A0A6J3D588
uniprot id: A0A6J3D596
uniprot id: A0A6J3D7G2
uniprot id: A0A6J3D7G7
uniprot id: A0A6J3D8A9
names: Similarity
messages: Belongs to the formin homology family.

219594:NPM2
gene id: 219594:NPM2
uniprot id: A0A6J3E8K0
uniprot id: A0A6J3EDN5
names: Similarity
messages: Belongs to the nucleoplasmin family.

219594:TMEM159
gene id: 219594:TMEM159
uniprot id: A0A6J3DT86
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LDAF1 family.
messages: Endoplasmic reticulum membrane
messages: Lipid droplet
messages: Membrane

219594:RBM15B
gene id: 219594:RBM15B
uniprot id: A0A6J3DLA9
names: Similarity
messages: Belongs to the RRM Spen family.

219594:FH
gene id: 219594:FH
uniprot id: A0A6J3CJH5
names: Function
names: Similarity
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
messages: Catalyzes the hydration of fumarate to L-malate in the tricarboxylic acid (TCA) cycle to facilitate a transition step in the production of energy in the form of NADH.

219594:NDE1
gene id: 219594:NDE1
uniprot id: A0A6J3DUZ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nudE family.
messages: centrosome
messages: spindle

219594:CLIC6
gene id: 219594:CLIC6
uniprot id: A0A6J3EIW6
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chloride channel CLIC family.
messages: Cytoplasm
messages: Members of this family may change from a globular, soluble state to a state where the N-terminal domain is inserted into the membrane and functions as chloride channel. A conformation change of the N-terminal domain is thought to expose hydrophobic surfaces that trigger membrane insertion.
messages: Membrane

219594:ZHX3
gene id: 219594:ZHX3
uniprot id: A0A6J3DRU5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZHX family.
messages: Nucleus

219594:NUDT2
gene id: 219594:NUDT2
uniprot id: A0A6J3EDA5
names: Similarity
messages: Belongs to the Nudix hydrolase family.

219594:ELF3
gene id: 219594:ELF3
uniprot id: A0A6J3E7W8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

219594:METTL15
gene id: 219594:METTL15
uniprot id: A0A6J3D517
names: Similarity
messages: Belongs to the methyltransferase superfamily. RsmH family.

219594:LOC116500950
gene id: 219594:LOC116500950
uniprot id: A0A6J3ELE3
names: Similarity
messages: Belongs to the EGF-CFC (Cripto-1/FRL1/Cryptic) family.

219594:CHUK
gene id: 219594:CHUK
uniprot id: A0A6J3D9M8
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

219594:CLDN11
gene id: 219594:CLDN11
uniprot id: A0A6J3DJ39
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

219594:NFX1
gene id: 219594:NFX1
uniprot id: A0A6J3CEB9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NFX1 family.
messages: Nucleus

219594:GPRC6A
gene id: 219594:GPRC6A
uniprot id: A0A6J3CQG2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

219594:DNAH1
gene id: 219594:DNAH1
uniprot id: A0A6J3DEV8
names: Similarity
messages: Belongs to the dynein heavy chain family.

219594:CLRN1
gene id: 219594:CLRN1
uniprot id: A0A6J3DGE4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the clarin family.
messages: Membrane

219594:RGS12
gene id: 219594:RGS12
uniprot id: A0A6J3D1S8
names: Subcellular Location Annotation
messages: Cytoplasm

219594:LOC116492687
gene id: 219594:LOC116492687
uniprot id: A0A6J3DD96
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the interleukin-1 receptor family.
messages: axon
messages: dendrite

219594:EGR1
gene id: 219594:EGR1
uniprot id: A0A6J3DN88
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EGR C2H2-type zinc-finger protein family.
messages: Nucleus
messages: Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'(EGR-site) in the promoter region of target genes. Binds double-stranded target DNA, irrespective of the cytosine methylation status. Regulates the transcription of numerous target genes, and thereby plays an important role in regulating the response to growth factors, DNA damage, and ischemia. Plays a role in the regulation of cell survival, proliferation and cell death.

219594:TRPM2
gene id: 219594:TRPM2
uniprot id: A0A6J3DH73
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transient receptor (TC 1.A.4) family. LTrpC subfamily. TRPM2 sub-subfamily.
messages: Cell membrane
messages: Membrane

219594:ECSIT
gene id: 219594:ECSIT
uniprot id: A0A6J3EB30
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ECSIT family.
messages: Cytoplasm
messages: Mitochondrion
messages: Nucleus

219594:IDH1
gene id: 219594:IDH1
uniprot id: A0A6J3D6R8
names: Cofactor
names: Similarity
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

219594:STK38L
gene id: 219594:STK38L
uniprot id: A0A6J3DAP3
names: Similarity
messages: Belongs to the protein kinase superfamily.

219594:TMEM38B
gene id: 219594:TMEM38B
uniprot id: A0A6J3ELE6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM38 family.
messages: Membrane
messages: Monovalent cation channel required for maintenance of rapid intracellular calcium release. May act as a potassium counter-ion channel that functions in synchronization with calcium release from intracellular stores.

219594:B3GALNT1
gene id: 219594:B3GALNT1
uniprot id: A0A6J3DE61
uniprot id: A0A6J3DH28
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane

219594:ACTR3B
gene id: 219594:ACTR3B
uniprot id: A0A6J3CJK8
uniprot id: A0A6J3CKT1
names: Similarity
messages: Belongs to the actin family.

219594:PRKAR2A
gene id: 219594:PRKAR2A
uniprot id: A0A6J3DKG1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cAMP-dependent kinase regulatory chain family.
messages: Cell membrane
messages: Membrane

219594:BAZ1B
gene id: 219594:BAZ1B
uniprot id: A0A6J3E467
names: Subcellular Location Annotation
messages: Nucleus

219594:TMEM135
gene id: 219594:TMEM135
uniprot id: A0A6J3D230
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM135 family.
messages: Membrane

219594:DLL1
gene id: 219594:DLL1
uniprot id: A0A6J3CRU8
names: Caution
names: Function
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Putative Notch ligand involved in the mediation of Notch signaling.

219594:MPV17
gene id: 219594:MPV17
uniprot id: A0A6J3CPY8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peroxisomal membrane protein PXMP2/4 family.
messages: Membrane

219594:ZNF830
gene id: 219594:ZNF830
uniprot id: A0A6J3CJL4
names: Subcellular Location Annotation
messages: Nucleus

219594:TP53BP2
gene id: 219594:TP53BP2
uniprot id: A0A6J3CNG5
names: Subcellular Location Annotation
messages: Nucleus

219594:STRIP1
gene id: 219594:STRIP1
uniprot id: A0A6J3E7R9
uniprot id: A0A6J3EAS0
names: Similarity
messages: Belongs to the STRIP family.

219594:FAM53A
gene id: 219594:FAM53A
uniprot id: A0A6J3CTM2
uniprot id: A0A6J3CVX9
names: Similarity
messages: Belongs to the FAM53 family.

219594:IRX5
gene id: 219594:IRX5
uniprot id: A0A6J3DM18
uniprot id: A0A6J3DPZ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TALE/IRO homeobox family.
messages: Nucleus

219594:RYR2
gene id: 219594:RYR2
uniprot id: A0A6J3CP36
uniprot id: A0A6J3CP42
uniprot id: A0A6J3CR25
uniprot id: A0A6J3CR31
uniprot id: A0A6J3CRR3
uniprot id: A0A6J3CRR8
uniprot id: A0A6J3CRS3
uniprot id: A0A6J3CU09
uniprot id: A0A6J3CU16
uniprot id: A0A6J3CU23
uniprot id: A0A6J3CV64
uniprot id: A0A6J3CV71
uniprot id: A0A6J3CV76
names: Subcellular Location Annotation
messages: Membrane
messages: Sarcoplasmic reticulum membrane

219594:CCNC
gene id: 219594:CCNC
uniprot id: A0A6J3CUM2
names: Similarity
messages: Belongs to the cyclin family.

219594:MRPL41
gene id: 219594:MRPL41
uniprot id: A0A6J3DZR7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mL41 family.
messages: Mitochondrion

219594:FAT3
gene id: 219594:FAT3
uniprot id: A0A6J3DKP3
uniprot id: A0A6J3DR66
uniprot id: A0A6J3DR72
uniprot id: A0A6J3DS09
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:RTCA
gene id: 219594:RTCA
uniprot id: A0A6J3DD39
names: Function
names: Similarity
messages: Belongs to the RNA 3'-terminal cyclase family. Type 1 subfamily.
messages: Catalyzes the conversion of 3'-phosphate to a 2',3'-cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps: (A) adenylation of the enzyme by ATP; (B) transfer of adenylate to an RNA-N3'P to produce RNA-N3'PP5'A; (C) and attack of the adjacent 2'-hydroxyl on the 3'-phosphorus in the diester linkage to produce the cyclic end product. The biological role of this enzyme is unknown but it is likely to function in some aspects of cellular RNA processing.

219594:CALCB
gene id: 219594:CALCB
uniprot id: A0A6J3D4P5
uniprot id: A0A6J3D6X5
uniprot id: A0A6J3D7R9
names: Similarity
messages: Belongs to the calcitonin family.

219594:LOC116501106
gene id: 219594:LOC116501106
uniprot id: A0A6J3EGQ1
uniprot id: A0A6J3EKE9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTF2H2 family.
messages: Nucleus

219594:LOC116487085
gene id: 219594:LOC116487085
uniprot id: A0A6J3CNC6
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL22 family.

219594:LOC116500557
gene id: 219594:LOC116500557
uniprot id: A0A6J3ECT9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alpha/beta interferon family.
messages: Has antiviral activities.
messages: Secreted

219594:GNAS
gene id: 219594:GNAS
uniprot id: A0A6J3DRE3
uniprot id: A0A6J3DVS0
names: Similarity
messages: Belongs to the G-alpha family. G(s) subfamily.

219594:LOC116502111
gene id: 219594:LOC116502111
uniprot id: A0A6J3EJ14
names: Similarity
messages: Belongs to the Arg-specific ADP-ribosyltransferase family.

219594:GATB
gene id: 219594:GATB
uniprot id: A0A6J3CVI5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in the mitochondria. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Mitochondrion
messages: Subunit of the heterotrimeric GatCAB amidotransferase (AdT) complex, composed of A (QRSL1), B (GATB) and C (GATC) subunits.

219594:LIPT1
gene id: 219594:LIPT1
uniprot id: A0A6J3DNT7
names: Similarity
messages: Belongs to the LplA family.

219594:GPR1
gene id: 219594:GPR1
uniprot id: A0A6J3DAM8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Belongs to the chemokine-like receptor (CMKLR) family.
messages: Cell membrane
messages: Membrane

219594:MMP9
gene id: 219594:MMP9
uniprot id: A0A6J3DX21
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M10A family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Can bind about 5 Ca(2+) ions per subunit.
messages: extracellular matrix

219594:BNIP1
gene id: 219594:BNIP1
uniprot id: A0A6J3DNT6
names: Subcellular Location Annotation
messages: Membrane

219594:VIPR1
gene id: 219594:VIPR1
uniprot id: A0A6J3CQM4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 2 family.
messages: Cell membrane
messages: Membrane

219594:SESN3
gene id: 219594:SESN3
uniprot id: A0A6J3CDJ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sestrin family.
messages: Cytoplasm

219594:LOC116501329
gene id: 219594:LOC116501329
uniprot id: A0A6J3ELJ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

219594:RBL2
gene id: 219594:RBL2
uniprot id: A0A6J3DLF8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the retinoblastoma protein (RB) family.
messages: Nucleus

219594:NMT1
gene id: 219594:NMT1
uniprot id: A0A6J3E4M0
names: Function
names: Similarity
messages: Adds a myristoyl group to the N-terminal glycine residue of certain cellular proteins.
messages: Belongs to the NMT family.

219594:LNPEP
gene id: 219594:LNPEP
uniprot id: A0A6J3EDR4
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M1 family.
messages: Binds 1 zinc ion per subunit.

219594:TOP1MT
gene id: 219594:TOP1MT
uniprot id: A0A6J3CKY8
uniprot id: A0A6J3CPC0
names: Function
names: Similarity
messages: Belongs to the type IB topoisomerase family.
messages: Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus removing DNA supercoils. Finally, in the religation step, the DNA 5'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

219594:SOSTDC1
gene id: 219594:SOSTDC1
uniprot id: A0A6J3CGM1
names: Caution
names: Similarity
messages: Belongs to the sclerostin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:STAG2
gene id: 219594:STAG2
uniprot id: A0A6J3DMV4
uniprot id: A0A6J3DRM9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SCC3 family.
messages: Chromosome
messages: Component of cohesin complex, a complex required for the cohesion of sister chromatids after DNA replication. The cohesin complex apparently forms a large proteinaceous ring within which sister chromatids can be trapped. At anaphase, the complex is cleaved and dissociates from chromatin, allowing sister chromatids to segregate.
messages: Nucleus
messages: Part of the cohesin complex which is composed of a heterodimer between a SMC1 protein (SMC1A or SMC1B) and SMC3, which are attached via their hinge domain, and RAD21 which link them at their heads, and one STAG protein.
messages: centromere

219594:LPIN2
gene id: 219594:LPIN2
uniprot id: A0A6J3CMB3
names: Similarity
messages: Belongs to the lipin family.

219594:LOC116489534
gene id: 219594:LOC116489534
uniprot id: A0A6J3D3R5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:LOC116495709
gene id: 219594:LOC116495709
uniprot id: A0A6J3DWG5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

219594:LOC116495811
gene id: 219594:LOC116495811
uniprot id: A0A6J3DUN4
names: Similarity
messages: Belongs to the cytochrome P450 family.

219594:DIAPH3
gene id: 219594:DIAPH3
uniprot id: A0A6J3ERX8
names: Similarity
messages: Belongs to the formin homology family. Diaphanous subfamily.

219594:SPTAN1
gene id: 219594:SPTAN1
uniprot id: A0A6J3DYV8
uniprot id: A0A6J3DYW0
uniprot id: A0A6J3E187
uniprot id: A0A6J3E222
uniprot id: A0A6J3E368
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the spectrin family.
messages: cell cortex
messages: cytoskeleton

219594:VPS41
gene id: 219594:VPS41
uniprot id: A0A6J3CD63
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VPS41 family.
messages: Early endosome membrane
messages: Endosome membrane
messages: Late endosome membrane
messages: Lysosome membrane
messages: Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport pathways.
messages: Vesicle
messages: clathrin-coated vesicle
messages: trans-Golgi network

219594:SPIRE1
gene id: 219594:SPIRE1
uniprot id: A0A6J3CFN8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the spire family.
messages: Cell membrane
messages: Cytoplasmic vesicle membrane
messages: Membrane
messages: cytoskeleton

219594:SLC30A8
gene id: 219594:SLC30A8
uniprot id: A0A6J3CL49
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily.
messages: Membrane

219594:HOXB6
gene id: 219594:HOXB6
uniprot id: A0A6J3E959
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Antp homeobox family.
messages: Nucleus

219594:NR2F6
gene id: 219594:NR2F6
uniprot id: A0A6J3EEP8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

219594:MRPL37
gene id: 219594:MRPL37
uniprot id: A0A6J3DD77
names: Subcellular Location Annotation
messages: Mitochondrion

219594:RBFOX2
gene id: 219594:RBFOX2
uniprot id: A0A6J3CZ60
uniprot id: A0A6J3D1R5
uniprot id: A0A6J3D1S9
uniprot id: A0A6J3D543
names: Function
names: Subcellular Location Annotation
messages: Nucleus
messages: RNA-binding protein that regulates alternative splicing events.

219594:LIN7A
gene id: 219594:LIN7A
uniprot id: A0A6J3CF39
uniprot id: A0A6J3CJM3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lin-7 family.
messages: Cell junction
messages: Cell membrane
messages: Membrane
messages: Plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells.

219594:CHPT1
gene id: 219594:CHPT1
uniprot id: A0A6J3CWF2
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

219594:SLC39A11
gene id: 219594:SLC39A11
uniprot id: A0A6J3DYP4
names: Subcellular Location Annotation
messages: Membrane

219594:FAM135B
gene id: 219594:FAM135B
uniprot id: A0A6J3CIX3
uniprot id: A0A6J3CK31
names: Similarity
messages: Belongs to the FAM135 family.

219594:SEPTIN9
gene id: 219594:SEPTIN9
uniprot id: A0A6J3DVX8
uniprot id: A0A6J3E039
uniprot id: A0A6J3E0X3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.
messages: Cytoplasm

219594:PSPC1
gene id: 219594:PSPC1
uniprot id: A0A6J3D2Y8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PSPC family.
messages: Cytoplasm
messages: Nucleus matrix
messages: Nucleus speckle
messages: nucleolus

219594:PEX5
gene id: 219594:PEX5
uniprot id: A0A6J3CI26
uniprot id: A0A6J3CLP8
names: Similarity
messages: Belongs to the peroxisomal targeting signal receptor family.

219594:MLNR
gene id: 219594:MLNR
uniprot id: A0A6J3EEC9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

219594:TMEM258
gene id: 219594:TMEM258
uniprot id: A0A6J3D644
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OST5 family.
messages: Component of the oligosaccharyltransferase (OST) complex.
messages: Membrane
messages: Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All subunits are required for a maximal enzyme activity.

219594:TAF10
gene id: 219594:TAF10
uniprot id: A0A6J3DZN7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAF10 family.
messages: Nucleus

219594:SLC12A9
gene id: 219594:SLC12A9
uniprot id: A0A6J3DHA2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC12A transporter family.
messages: Membrane

219594:ATP6V0A2
gene id: 219594:ATP6V0A2
uniprot id: A0A6J3DZV8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the V-ATPase 116 kDa subunit family.
messages: Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.
messages: Membrane

219594:CNN2
gene id: 219594:CNN2
uniprot id: A0A6J3E8S0
names: Function
names: Similarity
messages: Belongs to the calponin family.
messages: Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity.

219594:LOC116499592
gene id: 219594:LOC116499592
uniprot id: A0A6J3EFY5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the selenium-binding protein family.
messages: Catalyzes the oxidation of methanethiol, an organosulfur compound known to be produced in substantial amounts by gut bacteria. Selenium-binding protein which may be involved in the sensing of reactive xenobiotics in the cytoplasm. May be involved in intra-Golgi protein transport.
messages: Membrane
messages: Nucleus
messages: cytosol

219594:LOC116498319
gene id: 219594:LOC116498319
uniprot id: A0A6J3E8K8
names: Similarity
names: Subunit
messages: Belongs to the avian keratin family.
messages: The avian keratins (F-ker, S-ker, C-ker and B-ker) are a complex mixture of very similar polypeptides.

219594:CERS5
gene id: 219594:CERS5
uniprot id: A0A6J3EBK7
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Nucleus

219594:NUMB
gene id: 219594:NUMB
uniprot id: A0A6J3D478
uniprot id: A0A6J3D4L2
uniprot id: A0A6J3D6T5
uniprot id: A0A6J3D7M7
names: Function
messages: Plays a role in the process of neurogenesis.

219594:ARL6
gene id: 219594:ARL6
uniprot id: A0A6J3EIS7
uniprot id: A0A6J3EK40
uniprot id: A0A6J3EP21
uniprot id: A0A6J3EQG6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Arf family.
messages: cilium membrane

219594:S100Z
gene id: 219594:S100Z
uniprot id: A0A6J3EKC2
names: Similarity
messages: Belongs to the S-100 family.

219594:FOXO1
gene id: 219594:FOXO1
uniprot id: A0A6J3EI11
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

219594:LOC116492186
gene id: 219594:LOC116492186
uniprot id: A0A6J3DEQ5
names: Similarity
messages: Belongs to the amidase family.

219594:SCN8A
gene id: 219594:SCN8A
uniprot id: A0A6J3EFF7
uniprot id: A0A6J3EH37
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium channel (TC 1.A.1.10) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient.
messages: Membrane

219594:EIF4H
gene id: 219594:EIF4H
uniprot id: A0A6J3DZ68
uniprot id: A0A6J3E3F6
names: Function
names: Subcellular Location Annotation
messages: Stimulates the RNA helicase activity of EIF4A in the translation initiation complex. Binds weakly mRNA.
messages: perinuclear region

219594:TLN1
gene id: 219594:TLN1
uniprot id: A0A6J3ED94
names: Subcellular Location Annotation
messages: cytoskeleton

219594:MICOS13
gene id: 219594:MICOS13
uniprot id: A0A6J3EDV8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MICOS complex subunit Mic13 family.
messages: Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane.
messages: Component of the mitochondrial contact site and cristae organizing system (MICOS) complex.
messages: Membrane
messages: Mitochondrion inner membrane

219594:ST6GALNAC5
gene id: 219594:ST6GALNAC5
uniprot id: A0A6J3DGS4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

219594:LOC116496247
gene id: 219594:LOC116496247
uniprot id: A0A6J3DWI1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transferrin family.
messages: Monomer.
messages: Secreted

219594:LOC116498568
gene id: 219594:LOC116498568
uniprot id: A0A6J3EA76
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associates with GIRK2, GIRK3 or GIRK4 to form a G-protein activated heteromultimer pore-forming unit. The resulting inward current is much larger.
messages: Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family. KCNJ3 subfamily.
messages: Membrane
messages: This potassium channel is controlled by G proteins. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. This receptor plays a crucial role in regulating the heartbeat.

219594:LHX6
gene id: 219594:LHX6
uniprot id: A0A6J3DXY6
names: Subcellular Location Annotation
messages: Nucleus

219594:FKTN
gene id: 219594:FKTN
uniprot id: A0A6J3EK54
names: Similarity
messages: Belongs to the LicD transferase family.

219594:TMEM237
gene id: 219594:TMEM237
uniprot id: A0A6J3D8R9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM237 family.
messages: Component of the transition zone in primary cilia. Required for ciliogenesis.
messages: Membrane
messages: cilium

219594:LOC116495389
gene id: 219594:LOC116495389
uniprot id: A0A6J3DWK7
names: Similarity
messages: Belongs to the DNase I family.

219594:LOC116499732
gene id: 219594:LOC116499732
uniprot id: A0A6J3EE75
names: Similarity
names: Subunit
messages: Belongs to the avian keratin family.
messages: The avian keratins (F-ker, S-ker, C-ker and B-ker) are a complex mixture of very similar polypeptides.

219594:PAPSS1
gene id: 219594:PAPSS1
uniprot id: A0A6J3CSA8
names: Similarity
messages: In the C-terminal section; belongs to the sulfate adenylyltransferase family.
messages: In the N-terminal section; belongs to the APS kinase family.

219594:METTL8
gene id: 219594:METTL8
uniprot id: A0A6J3D595
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily. METL family.
messages: S-adenosyl-L-methionine-dependent methyltransferase.

219594:KHDRBS1
gene id: 219594:KHDRBS1
uniprot id: A0A6J3E871
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KHDRBS family.
messages: Cytoplasm

219594:SLCO4C1
gene id: 219594:SLCO4C1
uniprot id: A0A6J3EJR9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the organo anion transporter (TC 2.A.60) family.
messages: Cell membrane
messages: Membrane
messages: Secreted

219594:LOC116497897
gene id: 219594:LOC116497897
uniprot id: A0A6J3E8V0
names: Subcellular Location Annotation
messages: Membrane

219594:LOC116498660
gene id: 219594:LOC116498660
uniprot id: A0A6J3EAH9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for adenosine. The activity of this receptor is mediated by G proteins which inhibit adenylyl cyclase.

219594:TRAPPC4
gene id: 219594:TRAPPC4
uniprot id: A0A6J3E3R3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAPP small subunits family.
messages: Endoplasmic reticulum
messages: Part of the multisubunit transport protein particle (TRAPP) complex.
messages: cis-Golgi network

219594:GLI3
gene id: 219594:GLI3
uniprot id: A0A6J3CMT7
names: Similarity
messages: Belongs to the GLI C2H2-type zinc-finger protein family.

219594:ABCB7
gene id: 219594:ABCB7
uniprot id: A0A6J3DSN4
names: Subcellular Location Annotation
messages: Membrane

219594:LAPTM5
gene id: 219594:LAPTM5
uniprot id: A0A6J3E9Q3
names: Similarity
messages: Belongs to the LAPTM4/LAPTM5 transporter family.

219594:STAT6
gene id: 219594:STAT6
uniprot id: A0A6J3EFH6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transcription factor STAT family.
messages: Cytoplasm
messages: Nucleus

219594:LOC116496233
gene id: 219594:LOC116496233
uniprot id: A0A6J3DYR9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleotide-sugar transporter family. SLC35A subfamily.
messages: Golgi apparatus membrane
messages: Membrane

219594:POP4
gene id: 219594:POP4
uniprot id: A0A6J3DRE6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic/archaeal RNase P protein component 1 family.
messages: Component of nuclear RNase P and RNase MRP.
messages: Component of ribonuclease P, a ribonucleoprotein complex that generates mature tRNA molecules by cleaving their 5'-ends.
messages: nucleolus

219594:MRPS18C
gene id: 219594:MRPS18C
uniprot id: A0A6J3CSX3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS18 family.

219594:CD40
gene id: 219594:CD40
uniprot id: A0A6J3DX95
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:KBTBD8
gene id: 219594:KBTBD8
uniprot id: A0A6J3DJD5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KBTBD8 family.
messages: Golgi apparatus
messages: spindle

219594:XPA
gene id: 219594:XPA
uniprot id: A0A6J3EJU6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the XPA family.
messages: Nucleus

219594:FZD2
gene id: 219594:FZD2
uniprot id: A0A6J3EB45
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor Fz/Smo family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

219594:LOC116488914
gene id: 219594:LOC116488914
uniprot id: A0A6J3CXB8
names: Subcellular Location Annotation
messages: Secreted

219594:SFRP2
gene id: 219594:SFRP2
uniprot id: A0A6J3CWD3
names: Caution
names: Similarity
messages: Belongs to the secreted frizzled-related protein (sFRP) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:NDC80
gene id: 219594:NDC80
uniprot id: A0A6J3CNM9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity.
messages: Belongs to the NDC80/HEC1 family.
messages: Component of the NDC80 complex.
messages: Nucleus
messages: kinetochore

219594:TMEM184B
gene id: 219594:TMEM184B
uniprot id: A0A6J3E8L1
uniprot id: A0A6J3EDU5
names: Subcellular Location Annotation
messages: Membrane

219594:LHX5
gene id: 219594:LHX5
uniprot id: A0A6J3E0W7
names: Subcellular Location Annotation
messages: Nucleus

219594:CDH9
gene id: 219594:CDH9
uniprot id: A0A6J3CJ76
uniprot id: A0A6J3CQ69
names: Function
names: Subcellular Location Annotation
messages: Cadherins are calcium-dependent cell adhesion proteins.
messages: Cell membrane

219594:SLC12A3
gene id: 219594:SLC12A3
uniprot id: A0A6J3DJH5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC12A transporter family.
messages: Membrane

219594:EFTUD2
gene id: 219594:EFTUD2
uniprot id: A0A6J3EBE4
names: Subcellular Location Annotation
messages: Nucleus

219594:POLR3K
gene id: 219594:POLR3K
uniprot id: A0A6J3DRF9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family.
messages: Component of the RNA polymerase III (Pol III) complex consisting of 17 subunits.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: nucleolus

219594:LOC116493521
gene id: 219594:LOC116493521
uniprot id: A0A6J3DLG1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

219594:HOXD11
gene id: 219594:HOXD11
uniprot id: A0A6J3DAQ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Abd-B homeobox family.
messages: Nucleus

219594:MEF2B
gene id: 219594:MEF2B
uniprot id: A0A6J3E893
names: Subcellular Location Annotation
messages: Nucleus

219594:USP4
gene id: 219594:USP4
uniprot id: A0A6J3DHW3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C19 family.
messages: Cytoplasm
messages: Nucleus

219594:CZH5orf63
gene id: 219594:CZH5orf63
uniprot id: A0A6J3EGX3
names: Similarity
messages: Belongs to the glutaredoxin family.

219594:FA2H
gene id: 219594:FA2H
uniprot id: A0A6J3DIW6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sterol desaturase family. SCS7 subfamily.
messages: Binds 2 Zn(2+) ions per subunit that likely form a catalytic dimetal center.
messages: Catalyzes stereospecific hydroxylation of free fatty acids at the C-2 position to produce (R)-2-hydroxy fatty acids, which are building blocks of sphingolipids and glycosphingolipids common in neural tissue and epidermis. Plays an essential role in the synthesis of galactosphingolipids of the myelin sheath. Responsible for the synthesis of sphingolipids and glycosphingolipids involved in the formation of epidermal lamellar bodies critical for skin permeability barrier. Participates in the synthesis of glycosphingolipids and a fraction of type II wax diesters in sebaceous gland, specifically regulating hair follicle homeostasis. Involved in the synthesis of sphingolipids of plasma membrane rafts, controlling lipid raft mobility and trafficking of raft-associated proteins.
messages: Endoplasmic reticulum membrane
messages: Membrane

219594:CALHM2
gene id: 219594:CALHM2
uniprot id: A0A6J3DDU3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CALHM family.
messages: Membrane

219594:LOC116488699
gene id: 219594:LOC116488699
uniprot id: A0A6J3CYK2
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

219594:B3GALNT2
gene id: 219594:B3GALNT2
uniprot id: A0A6J3CNP7
uniprot id: A0A6J3CQX1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane

219594:CLDN19
gene id: 219594:CLDN19
uniprot id: A0A6J3E2D8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

219594:FOXC1
gene id: 219594:FOXC1
uniprot id: A0A6J3CMB5
names: Subcellular Location Annotation
messages: Nucleus

219594:GART
gene id: 219594:GART
uniprot id: A0A6J3DBS7
names: Similarity
messages: In the C-terminal section; belongs to the GART family.
messages: In the N-terminal section; belongs to the GARS family.
messages: In the central section; belongs to the AIR synthase family.

219594:SLC52A3
gene id: 219594:SLC52A3
uniprot id: A0A6J3DX54
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the riboflavin transporter family.
messages: Cell membrane
messages: Membrane
messages: Plasma membrane transporter mediating the uptake by cells of the water soluble vitamin B2/riboflavin that plays a key role in biochemical oxidation-reduction reactions of the carbohydrate, lipid, and amino acid metabolism.

219594:PHGDH
gene id: 219594:PHGDH
uniprot id: A0A6J3DFV4
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

219594:CGA
gene id: 219594:CGA
uniprot id: A0A6J3CQX3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycoprotein hormones subunit alpha family.
messages: Heterodimer of an alpha and a beta chain.
messages: Secreted

219594:FAT4
gene id: 219594:FAT4
uniprot id: A0A6J3CZB4
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:PITX1
gene id: 219594:PITX1
uniprot id: A0A6J3DSN1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the paired homeobox family. Bicoid subfamily.
messages: Nucleus

219594:B3GALT6
gene id: 219594:B3GALT6
uniprot id: A0A6J3E5F5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane

219594:JMJD1C
gene id: 219594:JMJD1C
uniprot id: A0A6J3D5F9
uniprot id: A0A6J3DAU5
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the JHDM2 histone demethylase family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Histone demethylase that specifically demethylates 'Lys-9' of histone H3, thereby playing a central role in histone code.
messages: Leu-Xaa-Xaa-Leu-Leu (LXXLL) motifs are known to mediate the association with nuclear receptors.
messages: Nucleus
messages: The JmjC domain and the C6-type zinc-finger are required for the demethylation activity.

219594:AOC1
gene id: 219594:AOC1
uniprot id: A0A6J3CLW5
names: Cofactor
names: PTM
names: Similarity
messages: Belongs to the copper/topaquinone oxidase family.
messages: Contains 1 topaquinone per subunit.
messages: Topaquinone (TPQ) is generated by copper-dependent autoxidation of a specific tyrosyl residue.

219594:MED13L
gene id: 219594:MED13L
uniprot id: A0A6J3DZB0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 13 family.
messages: Component of the Mediator complex, a coactivator involved in regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex.
messages: Nucleus

219594:DRAM2
gene id: 219594:DRAM2
uniprot id: A0A6J3EB07
names: Subcellular Location Annotation
messages: Membrane

219594:RPL23A
gene id: 219594:RPL23A
uniprot id: A0A6J3E5G9
names: Similarity
messages: Belongs to the universal ribosomal protein uL23 family.

219594:MID2
gene id: 219594:MID2
uniprot id: A0A6J3DNK8
names: Subcellular Location Annotation
messages: cytoskeleton

219594:LYPLA2
gene id: 219594:LYPLA2
uniprot id: A0A6J3E3W7
names: Similarity
messages: Belongs to the AB hydrolase superfamily. AB hydrolase 2 family.

219594:USP13
gene id: 219594:USP13
uniprot id: A0A6J3DJ29
names: Similarity
messages: Belongs to the peptidase C19 family.

219594:LOC116492139
gene id: 219594:LOC116492139
uniprot id: A0A6J3DEF3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TOR1AIP family.
messages: Membrane

219594:PDGFRB
gene id: 219594:PDGFRB
uniprot id: A0A6J3DMF0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.
messages: Cell membrane
messages: Membrane

219594:UBE2T
gene id: 219594:UBE2T
uniprot id: A0A6J3EB52
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

219594:RPL3L
gene id: 219594:RPL3L
uniprot id: A0A6J3DVG6
names: Similarity
messages: Belongs to the universal ribosomal protein uL3 family.

219594:EFNA4
gene id: 219594:EFNA4
uniprot id: A0A6J3EDN2
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ephrin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

219594:RBP7
gene id: 219594:RBP7
uniprot id: A0A6J3E2C6
names: Similarity
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.

219594:KDR
gene id: 219594:KDR
uniprot id: A0A6J3D1T8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.
messages: Cell membrane
messages: Membrane

219594:FST
gene id: 219594:FST
uniprot id: A0A6J3EDF8
uniprot id: A0A6J3EIA2
uniprot id: A0A6J3EIL7
names: Subcellular Location Annotation
messages: Secreted

219594:SLC2A2
gene id: 219594:SLC2A2
uniprot id: A0A6J3DIE4
uniprot id: A0A6J3DIZ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. Glucose transporter subfamily.
messages: Cell membrane
messages: Membrane

219594:SKA1
gene id: 219594:SKA1
uniprot id: A0A6J3EJ85
names: Similarity
messages: Belongs to the SKA1 family.

219594:TXNRD3
gene id: 219594:TXNRD3
uniprot id: A0A6J3DEL3
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

219594:ERO1B
gene id: 219594:ERO1B
uniprot id: A0A6J3CKY6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EROs family.
messages: Endoplasmic reticulum membrane

219594:RBPJL
gene id: 219594:RBPJL
uniprot id: A0A6J3DUL9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Su(H) family.
messages: Nucleus

219594:FAM162A
gene id: 219594:FAM162A
uniprot id: A0A6J3DCU3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0389 family.
messages: Membrane

219594:BARX2
gene id: 219594:BARX2
uniprot id: A0A6J3E6Z2
names: Subcellular Location Annotation
messages: Nucleus

219594:LOC116489555
gene id: 219594:LOC116489555
uniprot id: A0A6J3D2Q4
names: Subcellular Location Annotation
messages: Membrane

219594:DZIP1
gene id: 219594:DZIP1
uniprot id: A0A6J3EC86
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DZIP C2H2-type zinc-finger protein family.
messages: cilium basal body

219594:SLC66A1
gene id: 219594:SLC66A1
uniprot id: A0A6J3E2M7
names: Subcellular Location Annotation
messages: Membrane

219594:SLC25A44
gene id: 219594:SLC25A44
uniprot id: A0A6J3EBE8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

219594:XKR4
gene id: 219594:XKR4
uniprot id: A0A6J3CJX3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the XK family.
messages: Membrane

219594:LOC116491707
gene id: 219594:LOC116491707
uniprot id: A0A6J3DBD2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IAP family.
messages: Cytoplasm
messages: Nucleus

219594:IDNK
gene id: 219594:IDNK
uniprot id: A0A6J3EH67
names: Similarity
messages: Belongs to the gluconokinase GntK/GntV family.

219594:TUSC3
gene id: 219594:TUSC3
uniprot id: A0A6J3CSP3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OST3/OST6 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

219594:STK32A
gene id: 219594:STK32A
uniprot id: A0A6J3DT53
names: Similarity
messages: Belongs to the protein kinase superfamily.

219594:LOC116487540
gene id: 219594:LOC116487540
uniprot id: A0A6J3CT01
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. Very large inducible GTPase (VLIG) family.
messages: Nucleus

219594:MEF2C
gene id: 219594:MEF2C
uniprot id: A0A6J3ECA6
uniprot id: A0A6J3EDM6
uniprot id: A0A6J3EH36
uniprot id: A0A6J3EH40
uniprot id: A0A6J3EHC4
uniprot id: A0A6J3EJ07
names: Subcellular Location Annotation
messages: Nucleus

219594:PHAX
gene id: 219594:PHAX
uniprot id: A0A6J3EJ78
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PHAX family.
messages: Cytoplasm

219594:PIK3CG
gene id: 219594:PIK3CG
uniprot id: A0A6J3E5Z8
names: Similarity
messages: Belongs to the PI3/PI4-kinase family. Type III PI4K subfamily.

219594:LAMC1
gene id: 219594:LAMC1
uniprot id: A0A6J3DAC3
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: basement membrane

219594:CILP
gene id: 219594:CILP
uniprot id: A0A6J3DIR6
names: Subcellular Location Annotation
messages: extracellular matrix

219594:ZHX1
gene id: 219594:ZHX1
uniprot id: A0A6J3CES3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZHX family.
messages: Nucleus

219594:ATP10B
gene id: 219594:ATP10B
uniprot id: A0A6J3DT03
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.
messages: Membrane

219594:PTPRG
gene id: 219594:PTPRG
uniprot id: A0A6J3DGU8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Receptor class 5 subfamily.
messages: Membrane

219594:LOC116494628
gene id: 219594:LOC116494628
uniprot id: A0A6J3DS59
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

219594:LOC116493976
gene id: 219594:LOC116493976
uniprot id: A0A6J3DQF0
names: Similarity
messages: Belongs to the type-B carboxylesterase/lipase family.

219594:PLAA
gene id: 219594:PLAA
uniprot id: A0A6J3EI12
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat PLAP family.
messages: Cytoplasm

219594:GGT1
gene id: 219594:GGT1
uniprot id: A0A6J3DV93
uniprot id: A0A6J3DZE3
uniprot id: A0A6J3E063
uniprot id: A0A6J3E193
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyltransferase family.
messages: Cleaves the gamma-glutamyl peptide bond of glutathione and glutathione conjugates.
messages: Membrane

219594:CLTCL1
gene id: 219594:CLTCL1
uniprot id: A0A6J3DZT3
uniprot id: A0A6J3E0W0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the clathrin heavy chain family.
messages: Clathrin is the major protein of the polyhedral coat of coated pits and vesicles.
messages: Cytoplasmic vesicle membrane
messages: Membrane
messages: coated pit

219594:RPS26
gene id: 219594:RPS26
uniprot id: A0A6J3EH64
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS26 family.

219594:CDK8
gene id: 219594:CDK8
uniprot id: A0A6J3E4Z4
uniprot id: A0A6J3EA03
uniprot id: A0A6J3EA13
names: Similarity
messages: Belongs to the protein kinase superfamily.

219594:KCNV1
gene id: 219594:KCNV1
uniprot id: A0A6J3CMZ3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the potassium channel family. V (TC 1.A.1.2) subfamily. Kv8.1/KCNV1 sub-subfamily.
messages: Heteromultimer with KCNB1 and KCNB2. Interacts with KCNC4 and KCND1.
messages: Membrane
messages: Potassium channel subunit that does not form functional channels by itself. Modulates KCNB1 and KCNB2 channel activity by shifting the threshold for inactivation to more negative values and by slowing the rate of inactivation. Can down-regulate the channel activity of KCNB1, KCNB2, KCNC4 and KCND1, possibly by trapping them in intracellular membranes.

219594:GOLT1A
gene id: 219594:GOLT1A
uniprot id: A0A6J3EAP1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GOT1 family.
messages: Golgi apparatus membrane
messages: May be involved in fusion of ER-derived transport vesicles with the Golgi complex.
messages: Membrane

219594:RPL11
gene id: 219594:RPL11
uniprot id: A0A6J3E4F6
names: Similarity
messages: Belongs to the universal ribosomal protein uL5 family.

219594:PANX1
gene id: 219594:PANX1
uniprot id: A0A6J3EI41
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pannexin family.
messages: Cell membrane
messages: Membrane
messages: S-nitrosylation inhibits channel currents and ATP release.
messages: Structural component of the gap junctions and the hemichannels.
messages: gap junction

219594:MCOLN1
gene id: 219594:MCOLN1
uniprot id: A0A6J3EB04
names: Subcellular Location Annotation
messages: Endosome membrane
messages: Membrane

219594:LOC116486622
gene id: 219594:LOC116486622
uniprot id: A0A6J3CLI1
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily.

219594:LOC116501393
gene id: 219594:LOC116501393
uniprot id: A0A6J3EGF2
uniprot id: A0A6J3EGF6
uniprot id: A0A6J3ELR7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SCAMP family.
messages: Membrane

219594:YES1
gene id: 219594:YES1
uniprot id: A0A6J3CJ61
names: Similarity
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.

219594:LOC116501474
gene id: 219594:LOC116501474
uniprot id: A0A6J3EM58
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

219594:NFIL3
gene id: 219594:NFIL3
uniprot id: A0A6J3EJS0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bZIP family. NFIL3 subfamily.
messages: May act as a transcriptional regulator of a number of proteins of the circadian clock.
messages: Nucleus

219594:PEX16
gene id: 219594:PEX16
uniprot id: A0A6J3CXV3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peroxin-16 family.
messages: Peroxisome membrane

219594:LOC116499666
gene id: 219594:LOC116499666
uniprot id: A0A6J3EE75
names: Similarity
names: Subunit
messages: Belongs to the avian keratin family.
messages: The avian keratins (F-ker, S-ker, C-ker and B-ker) are a complex mixture of very similar polypeptides.

219594:LOC116500668
gene id: 219594:LOC116500668
uniprot id: A0A6J3EDC1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome c oxidase VIIc family.
messages: Component of the cytochrome c oxidase (complex IV, CIV), a multisubunit enzyme composed of 14 subunits. The complex is composed of a catalytic core of 3 subunits, encoded in the mitochondrial DNA, and 11 supernumerary subunits, which are encoded in the nuclear genome. The complex exists as a monomer or a dimer and forms supercomplexes (SCs) in the inner mitochondrial membrane with NADH-ubiquinone oxidoreductase (complex I, CI) and ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII), resulting in different assemblies (supercomplex SCI(1)III(2)IV(1) and megacomplex MCI(2)III(2)IV(2)).
messages: Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)). The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
messages: Membrane
messages: Mitochondrion inner membrane

219594:ANXA6
gene id: 219594:ANXA6
uniprot id: A0A6J3DMU8
uniprot id: A0A6J3DQ65
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: A pair of annexin repeats may form one binding site for calcium and phospholipid.
messages: Belongs to the annexin family.
messages: May associate with CD21. May regulate the release of Ca(2+) from intracellular stores.
messages: Melanosome

219594:FBLN1
gene id: 219594:FBLN1
uniprot id: A0A6J3E0U1
uniprot id: A0A6J3E0V3
uniprot id: A0A6J3E3K8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the fibulin family.
messages: Homomultimerizes and interacts with various extracellular matrix components.
messages: Incorporated into fibronectin-containing matrix fibers. May play a role in cell adhesion and migration along protein fibers within the extracellular matrix (ECM). Could be important for certain developmental processes and contribute to the supramolecular organization of ECM architecture, in particular to those of basement membranes.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

219594:FAM8A1
gene id: 219594:FAM8A1
uniprot id: A0A6J3CHQ4
names: Subcellular Location Annotation
messages: Membrane

219594:SOX1
gene id: 219594:SOX1
uniprot id: A0A6J3EIG9
names: Subcellular Location Annotation
messages: Nucleus

219594:RBBP7
gene id: 219594:RBBP7
uniprot id: A0A6J3DIN3
names: Subcellular Location Annotation
messages: Nucleus

219594:GTF2I
gene id: 219594:GTF2I
uniprot id: A0A6J3E425
uniprot id: A0A6J3E538
names: Subcellular Location Annotation
messages: Nucleus

219594:SEMA6C
gene id: 219594:SEMA6C
uniprot id: A0A6J3E967
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:KIF26B
gene id: 219594:KIF26B
uniprot id: A0A6J3CMK2
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

219594:S100B
gene id: 219594:S100B
uniprot id: A0A6J3D639
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the S-100 family.
messages: Cytoplasm
messages: Nucleus
messages: Secreted

219594:MTIF3
gene id: 219594:MTIF3
uniprot id: A0A6J3ENC0
names: Similarity
messages: Belongs to the IF-3 family.

219594:FER
gene id: 219594:FER
uniprot id: A0A6J3EEK2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. Fes/fps subfamily.
messages: cytoskeleton

219594:SNX17
gene id: 219594:SNX17
uniprot id: A0A6J3CQB7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sorting nexin family.
messages: Cytoplasmic vesicle membrane
messages: Early endosome
messages: Endosome
messages: Membrane

219594:ISM1
gene id: 219594:ISM1
uniprot id: A0A6J3CS27
names: Similarity
messages: Belongs to the isthmin family.

219594:GNB3
gene id: 219594:GNB3
uniprot id: A0A6J3DZC1
names: Similarity
messages: Belongs to the WD repeat G protein beta family.

219594:CD99
gene id: 219594:CD99
uniprot id: A0A6J3E056
uniprot id: A0A6J3E2P5
uniprot id: A0A6J3E3I3
uniprot id: A0A6J3E3J7
names: Similarity
messages: Belongs to the CD99 family.

219594:CALHM6
gene id: 219594:CALHM6
uniprot id: A0A6J3CUC4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CALHM family.
messages: Membrane

219594:TBL1X
gene id: 219594:TBL1X
uniprot id: A0A6J3CU33
names: Similarity
messages: Belongs to the WD repeat EBI family.

219594:SLC25A38
gene id: 219594:SLC25A38
uniprot id: A0A6J3CK51
uniprot id: A0A6J3CM04
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family. SLC25A38 subfamily.
messages: Membrane
messages: Mitochondrial glycine transporter that imports glycine into the mitochondrial matrix. Plays an important role in providing glycine for the first enzymatic step in heme biosynthesis, the condensation of glycine with succinyl-CoA to produce 5-aminolevulinate (ALA) in the miochondrial matrix. Required during erythropoiesis.
messages: Mitochondrion inner membrane

219594:GALR2
gene id: 219594:GALR2
uniprot id: A0A6J3DWQ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

219594:MTX2
gene id: 219594:MTX2
uniprot id: A0A6J3D9T2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metaxin family.
messages: Membrane
messages: Mitochondrion outer membrane

219594:CACNG4
gene id: 219594:CACNG4
uniprot id: A0A6J3DWD5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily.
messages: Membrane
messages: Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs), including GRIA1 and GRIA4. Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization.

219594:FAM161B
gene id: 219594:FAM161B
uniprot id: A0A6J3D092
names: Similarity
messages: Belongs to the FAM161 family.

219594:LOC116500238
gene id: 219594:LOC116500238
uniprot id: A0A6J3ECU5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the immunoglobulin superfamily. BTN/MOG family.
messages: Membrane

219594:STAC
gene id: 219594:STAC
uniprot id: A0A6J3CE92
names: Subcellular Location Annotation
messages: sarcolemma

219594:HOXA13
gene id: 219594:HOXA13
uniprot id: A0A6J3CJ88
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Abd-B homeobox family.
messages: Nucleus

219594:EPHA1
gene id: 219594:EPHA1
uniprot id: A0A6J3DKS3
names: Subcellular Location Annotation
messages: Membrane

219594:GTF3C5
gene id: 219594:GTF3C5
uniprot id: A0A6J3E4D3
names: Subcellular Location Annotation
messages: Nucleus

219594:ZUP1
gene id: 219594:ZUP1
uniprot id: A0A6J3CU31
names: Similarity
names: Subunit
messages: Belongs to the peptidase C78 family. ZUFSP subfamily.
messages: Interacts with RPA1 and RPA2.

219594:INKA1
gene id: 219594:INKA1
uniprot id: A0A6J3DKQ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the INKA family.
messages: Nucleus

219594:LOC116498782
gene id: 219594:LOC116498782
uniprot id: A0A6J3ECN9
names: Cofactor
names: Similarity
messages: Belongs to the DNA photolyase class-1 family.
messages: Binds 1 FAD per subunit.

219594:SLC7A4
gene id: 219594:SLC7A4
uniprot id: A0A6J3E1D1
names: Subcellular Location Annotation
messages: Membrane

219594:SLC4A9
gene id: 219594:SLC4A9
uniprot id: A0A6J3DUI8
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Basolateral cell membrane
messages: Belongs to the anion exchanger (TC 2.A.31) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Lateral cell membrane
messages: Membrane

219594:STRA6
gene id: 219594:STRA6
uniprot id: A0A6J3DK94
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

219594:ADAMTS15
gene id: 219594:ADAMTS15
uniprot id: A0A6J3E755
names: Caution
names: Cofactor
names: Subcellular Location Annotation
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

219594:MINPP1
gene id: 219594:MINPP1
uniprot id: A0A6J3D976
names: Similarity
messages: Belongs to the histidine acid phosphatase family. MINPP1 subfamily.

219594:VWC2
gene id: 219594:VWC2
uniprot id: A0A6J3CJC6
names: Subcellular Location Annotation
messages: Synapse

219594:HECTD1
gene id: 219594:HECTD1
uniprot id: A0A6J3D1J0
uniprot id: A0A6J3D1J5
uniprot id: A0A6J3D3X5
uniprot id: A0A6J3D496
uniprot id: A0A6J3D4A1
uniprot id: A0A6J3D6H6
uniprot id: A0A6J3D7C6
uniprot id: A0A6J3D7C9
names: Function
names: Similarity
messages: Belongs to the UPL family. K-HECT subfamily.
messages: E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.

219594:LOC116499738
gene id: 219594:LOC116499738
uniprot id: A0A6J3E9U3
names: Similarity
names: Subunit
messages: Belongs to the avian keratin family.
messages: The avian keratins (F-ker, S-ker, C-ker and B-ker) are a complex mixture of very similar polypeptides.

219594:SASS6
gene id: 219594:SASS6
uniprot id: A0A6J3DF28
names: Subcellular Location Annotation
messages: centrosome

219594:TMTC3
gene id: 219594:TMTC3
uniprot id: A0A6J3CS85
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMTC family.
messages: Endoplasmic reticulum
messages: Membrane

219594:DPY19L1
gene id: 219594:DPY19L1
uniprot id: A0A6J3CGW0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dpy-19 family.
messages: Membrane
messages: Probable C-mannosyltransferase that mediates C-mannosylation of tryptophan residues on target proteins.

219594:PDK1
gene id: 219594:PDK1
uniprot id: A0A6J3D7A2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PDK/BCKDK protein kinase family.
messages: Mitochondrion matrix

219594:CDC26
gene id: 219594:CDC26
uniprot id: A0A6J3E3D0
names: Similarity
messages: Belongs to the CDC26 family.

219594:NATD1
gene id: 219594:NATD1
uniprot id: A0A6J3DVW0
names: Similarity
messages: Belongs to the NATD1 family.

219594:DIP2C
gene id: 219594:DIP2C
uniprot id: A0A6J3CEG8
uniprot id: A0A6J3CG40
uniprot id: A0A6J3CH27
uniprot id: A0A6J3CJ15
uniprot id: A0A6J3CKQ4
names: Similarity
messages: Belongs to the DIP2 family.

219594:ACSL6
gene id: 219594:ACSL6
uniprot id: A0A6J3DNN2
uniprot id: A0A6J3DQY5
uniprot id: A0A6J3DSZ3
uniprot id: A0A6J3DTV4
names: Function
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.
messages: Catalyzes the conversion of long-chain fatty acids to their active form acyl-CoAs for both synthesis of cellular lipids, and degradation via beta-oxidation.

219594:CHRND
gene id: 219594:CHRND
uniprot id: A0A6J3DI02
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

219594:LOC116502370
gene id: 219594:LOC116502370
uniprot id: A0A6J3EK32
names: Similarity
names: Subunit
messages: Belongs to the histone H3 family.
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

219594:CTSH
gene id: 219594:CTSH
uniprot id: A0A6J3DGZ4
names: Similarity
messages: Belongs to the peptidase C1 family.

219594:SLC41A3
gene id: 219594:SLC41A3
uniprot id: A0A6J3DJL5
uniprot id: A0A6J3DL79
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

219594:YPEL2
gene id: 219594:YPEL2
uniprot id: A0A6J3DZ58
names: Similarity
messages: Belongs to the yippee family.

219594:MYO1A
gene id: 219594:MYO1A
uniprot id: A0A6J3EBW5
uniprot id: A0A6J3EH82
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.

219594:LGR6
gene id: 219594:LGR6
uniprot id: A0A6J3E7A5
names: Subcellular Location Annotation
messages: Membrane

219594:LOC116501416
gene id: 219594:LOC116501416
uniprot id: A0A6J3EI30
uniprot id: A0A6J3ELS8
names: Similarity
messages: Belongs to the YOS1 family.

219594:SSTR4
gene id: 219594:SSTR4
uniprot id: A0A6J3CP06
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

219594:CCDC107
gene id: 219594:CCDC107
uniprot id: A0A6J3EJX9
names: Similarity
messages: Belongs to the ric-3 family.

219594:PNPLA1
gene id: 219594:PNPLA1
uniprot id: A0A6J3EC60
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:PDGFB
gene id: 219594:PDGFB
uniprot id: A0A6J3EL26
names: Similarity
messages: Belongs to the PDGF/VEGF growth factor family.

219594:OLA1
gene id: 219594:OLA1
uniprot id: A0A6J3D379
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.
messages: Cytoplasm
messages: Hydrolyzes ATP, and can also hydrolyze GTP with lower efficiency. Has lower affinity for GTP.
messages: Monomer.
messages: Nucleus
messages: nucleolus

219594:APC
gene id: 219594:APC
uniprot id: A0A6J3ECN6
uniprot id: A0A6J3EHI8
uniprot id: A0A6J3EHR4
names: Similarity
messages: Belongs to the adenomatous polyposis coli (APC) family.

219594:LOC116500320
gene id: 219594:LOC116500320
uniprot id: A0A6J3EGI8
names: Subcellular Location Annotation
messages: Membrane

219594:PAX4
gene id: 219594:PAX4
uniprot id: A0A6J3DQL0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the paired homeobox family.
messages: Nucleus

219594:B4GALT2
gene id: 219594:B4GALT2
uniprot id: A0A6J3DER6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 7 family.
messages: Golgi apparatus membrane
messages: Membrane
messages: Responsible for the synthesis of complex-type N-linked oligosaccharides in many glycoproteins as well as the carbohydrate moieties of glycolipids.

219594:DLGAP4
gene id: 219594:DLGAP4
uniprot id: A0A6J3DRM4
uniprot id: A0A6J3DRM8
uniprot id: A0A6J3DTT6
uniprot id: A0A6J3DVZ8
uniprot id: A0A6J3DWS7
uniprot id: A0A6J3DXT2
names: Similarity
messages: Belongs to the SAPAP family.

219594:HOXD8
gene id: 219594:HOXD8
uniprot id: A0A6J3D4D6
uniprot id: A0A6J3D7J7
names: Subcellular Location Annotation
messages: Nucleus

219594:C2H7orf25
gene id: 219594:C2H7orf25
uniprot id: A0A6J3CK08
names: Similarity
messages: Belongs to the UPF0415 family.

219594:LOC116498806
gene id: 219594:LOC116498806
uniprot id: A0A6J3E7I8
names: Similarity
messages: Belongs to the GST superfamily. Mu family.

219594:LOC116489509
gene id: 219594:LOC116489509
uniprot id: A0A6J3D2K0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

219594:C8H1orf52
gene id: 219594:C8H1orf52
uniprot id: A0A6J3DCP1
names: Similarity
messages: Belongs to the UPF0690 family.

219594:BCL2L14
gene id: 219594:BCL2L14
uniprot id: A0A6J3CPP4
names: Similarity
messages: Belongs to the Bcl-2 family.

219594:GINS3
gene id: 219594:GINS3
uniprot id: A0A6J3DMB7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GINS3/PSF3 family.
messages: Chromosome
messages: Component of the GINS complex.
messages: Nucleus
messages: The GINS complex plays an essential role in the initiation of DNA replication.

219594:ADAMTS8
gene id: 219594:ADAMTS8
uniprot id: A0A6J3E3X1
names: Caution
names: Cofactor
names: Subcellular Location Annotation
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

219594:MED7
gene id: 219594:MED7
uniprot id: A0A6J3DTU2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 7 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery.
messages: Component of the Mediator complex.
messages: Nucleus

219594:GATAD2A
gene id: 219594:GATAD2A
uniprot id: A0A6J3E6W1
uniprot id: A0A6J3EBY0
uniprot id: A0A6J3EDL3
names: Subcellular Location Annotation
messages: Nucleus

219594:SPOCK1
gene id: 219594:SPOCK1
uniprot id: A0A6J3DMZ6
uniprot id: A0A6J3DSB8
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

219594:LOC116498860
gene id: 219594:LOC116498860
uniprot id: A0A6J3EAV3
names: Similarity
messages: Belongs to the glycosyl hydrolase 18 family. Chitinase class II subfamily.

219594:TSPAN3
gene id: 219594:TSPAN3
uniprot id: A0A6J3DJP2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

219594:ST8SIA2
gene id: 219594:ST8SIA2
uniprot id: A0A6J3DNQ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

219594:SNRPF
gene id: 219594:SNRPF
uniprot id: A0A6J3DTI9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the snRNP Sm proteins family. SmF/LSm6 subfamily.
messages: Nucleus

219594:FAM171B
gene id: 219594:FAM171B
uniprot id: A0A6J3D565
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAM171 family.
messages: Membrane

219594:NR2F1
gene id: 219594:NR2F1
uniprot id: A0A6J3EKE6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

219594:LOC116500109
gene id: 219594:LOC116500109
uniprot id: A0A6J3EB51
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

219594:CLU
gene id: 219594:CLU
uniprot id: A0A6J3CQK3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the clusterin family.
messages: Endoplasmic reticulum
messages: Membrane
messages: Mitochondrion membrane
messages: Nucleus
messages: Secreted
messages: chromaffin granule
messages: cytosol

219594:HDAC10
gene id: 219594:HDAC10
uniprot id: A0A6J3EN33
names: Similarity
messages: Belongs to the histone deacetylase family. HD type 2 subfamily.

219594:LIN7C
gene id: 219594:LIN7C
uniprot id: A0A6J3D129
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lin-7 family.
messages: Cell junction
messages: Cell membrane
messages: Membrane
messages: Plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells.

219594:SOD3
gene id: 219594:SOD3
uniprot id: A0A6J3D037
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Cu-Zn superoxide dismutase family.
messages: Binds 1 copper ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

219594:DIPK2B
gene id: 219594:DIPK2B
uniprot id: A0A6J3EPG7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DIPK family.
messages: Secreted

219594:CTSC
gene id: 219594:CTSC
uniprot id: A0A6J3E9D9
names: Similarity
names: Subunit
messages: Belongs to the peptidase C1 family.
messages: Tetramer of heterotrimers consisting of exclusion domain, heavy- and light chains.

219594:LOC116489378
gene id: 219594:LOC116489378
uniprot id: A0A6J3CZA0
names: Similarity
messages: Belongs to the globin family.

219594:LOC116492755
gene id: 219594:LOC116492755
uniprot id: A0A6J3DJT4
names: Similarity
messages: Belongs to the cytochrome P450 family.

219594:PAX1
gene id: 219594:PAX1
uniprot id: A0A6J3CM91
names: Subcellular Location Annotation
messages: Nucleus

219594:LOC116494270
gene id: 219594:LOC116494270
uniprot id: A0A6J3DPN3
names: Similarity
messages: Belongs to the aldo/keto reductase family.

219594:LOC116495067
gene id: 219594:LOC116495067
uniprot id: A0A6J3DU34
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the noggin family.
messages: Homodimer.
messages: Secreted

219594:LOC116494761
gene id: 219594:LOC116494761
uniprot id: A0A6J3DRZ1
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

219594:ENDOU
gene id: 219594:ENDOU
uniprot id: A0A6J3EEX7
names: Similarity
names: Subunit
messages: Belongs to the ENDOU family.
messages: Monomer.

219594:BNIP3
gene id: 219594:BNIP3
uniprot id: A0A6J3DDR5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NIP3 family.
messages: Membrane

219594:PCYT2
gene id: 219594:PCYT2
uniprot id: A0A6J3DW11
uniprot id: A0A6J3E105
names: Similarity
messages: Belongs to the cytidylyltransferase family.

219594:CDK17
gene id: 219594:CDK17
uniprot id: A0A6J3CQ39
names: Similarity
messages: Belongs to the protein kinase superfamily.

219594:TP73
gene id: 219594:TP73
uniprot id: A0A6J3E161
uniprot id: A0A6J3E5E7
uniprot id: A0A6J3E662
uniprot id: A0A6J3E7B2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression.
messages: Belongs to the p53 family.
messages: Binds 1 zinc ion per subunit.
messages: Binds DNA as a homotetramer.
messages: Cytoplasm
messages: Found in a complex with p53/TP53 and CABLES1.
messages: Nucleus
messages: Participates in the apoptotic response to DNA damage. Isoforms containing the transactivation domain are pro-apoptotic, isoforms lacking the domain are anti-apoptotic and block the function of p53 and transactivating p73 isoforms. May be a tumor suppressor protein.

219594:LOC116500146
gene id: 219594:LOC116500146
uniprot id: A0A6J3EBB1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

219594:LOC116501988
gene id: 219594:LOC116501988
uniprot id: A0A6J3EJW4
names: Similarity
messages: Belongs to the PTEN phosphatase protein family.

219594:LOC116500217
gene id: 219594:LOC116500217
uniprot id: A0A6J3EBH3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the immunoglobulin superfamily. BTN/MOG family.
messages: Membrane

219594:LOC116500141
gene id: 219594:LOC116500141
uniprot id: A0A6J3EBA4
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:GRIN2B
gene id: 219594:GRIN2B
uniprot id: A0A6J3EJQ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Receptor for glutamate that functions as a ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system.
messages: Synaptic cell membrane

219594:ADSL
gene id: 219594:ADSL
uniprot id: A0A6J3DCL5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
messages: Catalyzes two non-sequential steps in de novo AMP synthesis: converts (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido)succinate (SAICAR) to fumarate plus 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide, and thereby also contributes to de novo IMP synthesis, and converts succinyladenosine monophosphate (SAMP) to AMP and fumarate.
messages: Homotetramer. Residues from neighboring subunits contribute catalytic and substrate-binding residues to each active site.

219594:ZFYVE28
gene id: 219594:ZFYVE28
uniprot id: A0A6J3CV29
uniprot id: A0A6J3CXD3
uniprot id: A0A6J3CYG8
names: Similarity
messages: Belongs to the lst-2 family.

219594:GOSR2
gene id: 219594:GOSR2
uniprot id: A0A6J3E663
uniprot id: A0A6J3E954
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GOSR2 family.
messages: Involved in transport of proteins from the cis/medial-Golgi to the trans-Golgi network.
messages: Membrane

219594:SLC5A6
gene id: 219594:SLC5A6
uniprot id: A0A6J3CVM1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

219594:POU6F1
gene id: 219594:POU6F1
uniprot id: A0A6J3EA51
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the POU transcription factor family.
messages: Nucleus

219594:LOC116487994
gene id: 219594:LOC116487994
uniprot id: A0A6J3CS83
uniprot id: A0A6J3CSQ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome b5 family.
messages: Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
messages: Endoplasmic reticulum

219594:PLEKHA8
gene id: 219594:PLEKHA8
uniprot id: A0A6J3CFN1
names: Subcellular Location Annotation
messages: trans-Golgi network membrane

219594:ABI3
gene id: 219594:ABI3
uniprot id: A0A6J3E9P1
names: Similarity
messages: Belongs to the ABI family.

219594:CACNA2D4
gene id: 219594:CACNA2D4
uniprot id: A0A6J3CNK5
names: Similarity
messages: Belongs to the calcium channel subunit alpha-2/delta family.

219594:OSBPL2
gene id: 219594:OSBPL2
uniprot id: A0A6J3DRH4
names: Similarity
messages: Belongs to the OSBP family.

219594:LOC116485601
gene id: 219594:LOC116485601
uniprot id: A0A6J3CFY7
names: Similarity
messages: Belongs to the serpin family.

219594:SP4
gene id: 219594:SP4
uniprot id: A0A6J3CIR1
uniprot id: A0A6J3CK60
names: Subcellular Location Annotation
messages: Nucleus

219594:AASDH
gene id: 219594:AASDH
uniprot id: A0A6J3CWN8
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

219594:BCL7A
gene id: 219594:BCL7A
uniprot id: A0A6J3DWK4
names: Similarity
messages: Belongs to the BCL7 family.

219594:UBE2G1
gene id: 219594:UBE2G1
uniprot id: A0A6J3E4I6
uniprot id: A0A6J3E5J2
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

219594:OCSTAMP
gene id: 219594:OCSTAMP
uniprot id: A0A6J3DYN4
names: Subcellular Location Annotation
messages: Membrane

219594:PSAP
gene id: 219594:PSAP
uniprot id: A0A6J3D8L6
uniprot id: A0A6J3DAT0
uniprot id: A0A6J3DBB0
names: Subcellular Location Annotation
messages: Secreted

219594:LOC116491970
gene id: 219594:LOC116491970
uniprot id: A0A6J3DFN1
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

219594:LOC116500177
gene id: 219594:LOC116500177
uniprot id: A0A6J3ECN8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the immunoglobulin superfamily. BTN/MOG family.
messages: Membrane

219594:SWI5
gene id: 219594:SWI5
uniprot id: A0A6J3E3F3
names: Function
names: Similarity
messages: Belongs to the SWI5/SAE3 family.
messages: Component of the swi5-sfr1 complex, a complex required for double-strand break repair via homologous recombination.

219594:CUL4B
gene id: 219594:CUL4B
uniprot id: A0A6J3DPN7
names: Similarity
messages: Belongs to the cullin family.

219594:KAT6A
gene id: 219594:KAT6A
uniprot id: A0A6J3EDE3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MYST (SAS/MOZ) family.
messages: Nucleus

219594:MRPL35
gene id: 219594:MRPL35
uniprot id: A0A6J3CYJ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial ribosomal protein bL35 family.
messages: Mitochondrion

219594:CORO2A
gene id: 219594:CORO2A
uniprot id: A0A6J3EJT4
names: Similarity
messages: Belongs to the WD repeat coronin family.

219594:GSTO1
gene id: 219594:GSTO1
uniprot id: A0A6J3D6W8
names: Function
names: Similarity
messages: Belongs to the GST superfamily. Omega family.
messages: Exhibits glutathione-dependent thiol transferase activity. Has high dehydroascorbate reductase activity and may contribute to the recycling of ascorbic acid. Participates in the biotransformation of inorganic arsenic and reduces monomethylarsonic acid (MMA).

219594:INA
gene id: 219594:INA
uniprot id: A0A6J3DAU9
names: Similarity
messages: Belongs to the intermediate filament family.

219594:DERL2
gene id: 219594:DERL2
uniprot id: A0A6J3E5X7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the derlin family.
messages: Endoplasmic reticulum membrane
messages: Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome.
messages: Membrane

219594:MTMR1
gene id: 219594:MTMR1
uniprot id: A0A6J3DQ00
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily.
messages: Cytoplasm

219594:SLC2A1
gene id: 219594:SLC2A1
uniprot id: A0A6J3E2Z1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane
messages: Photoreceptor inner segment

219594:RRP7A
gene id: 219594:RRP7A
uniprot id: A0A6J3DT18
names: Similarity
messages: Belongs to the RRP7 family.

219594:LOC116493565
gene id: 219594:LOC116493565
uniprot id: A0A6J3DHI9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

219594:MARS2
gene id: 219594:MARS2
uniprot id: A0A6J3DQN9
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

219594:PHC3
gene id: 219594:PHC3
uniprot id: A0A6J3DC61
uniprot id: A0A6J3DEU2
uniprot id: A0A6J3DG03
uniprot id: A0A6J3DHN4
names: Subcellular Location Annotation
messages: Nucleus

219594:UGP2
gene id: 219594:UGP2
uniprot id: A0A6J3CMQ7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UDPGP type 1 family.
messages: Homooctamer.
messages: UTP--glucose-1-phosphate uridylyltransferase catalyzing the conversion of glucose-1-phosphate into UDP-glucose, a crucial precursor for the production of glycogen.

219594:TUBGCP3
gene id: 219594:TUBGCP3
uniprot id: A0A6J3DY84
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TUBGCP family.
messages: Gamma-tubulin complex is necessary for microtubule nucleation at the centrosome.
messages: centrosome

219594:FAM161A
gene id: 219594:FAM161A
uniprot id: A0A6J3CMA2
names: Similarity
messages: Belongs to the FAM161 family.

219594:PHF20L1
gene id: 219594:PHF20L1
uniprot id: A0A6J3CE44
uniprot id: A0A6J3CGZ0
uniprot id: A0A6J3CIQ8
names: Subcellular Location Annotation
messages: Nucleus

219594:LOC116496878
gene id: 219594:LOC116496878
uniprot id: A0A6J3E1Y4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SURF1 family.
messages: Mitochondrion inner membrane
messages: Probably involved in the biogenesis of the COX complex.

219594:ATP8A2
gene id: 219594:ATP8A2
uniprot id: A0A6J3EJI0
uniprot id: A0A6J3EKU6
uniprot id: A0A6J3EPT0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.
messages: Membrane

219594:FAM83H
gene id: 219594:FAM83H
uniprot id: A0A6J3CM79
names: Similarity
messages: Belongs to the FAM83 family.

219594:LOC116487752
gene id: 219594:LOC116487752
uniprot id: A0A6J3CRQ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
messages: Membrane

219594:TTC36
gene id: 219594:TTC36
uniprot id: A0A6J3E3B5
uniprot id: A0A6J3E668
names: Similarity
messages: Belongs to the TTC36 family.

219594:LOC116493911
gene id: 219594:LOC116493911
uniprot id: A0A6J3DLK1
names: Function
names: Similarity
messages: Belongs to the metallothionein superfamily. Type 1 family.
messages: Metallothioneins have a high content of cysteine residues that bind various heavy metals.

219594:LOC116487999
gene id: 219594:LOC116487999
uniprot id: A0A6J3CS88
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

219594:RAP2C
gene id: 219594:RAP2C
uniprot id: A0A6J3DRX2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Ras family.
messages: Endosome membrane
messages: Recycling endosome membrane

219594:CPE
gene id: 219594:CPE
uniprot id: A0A6J3CUH4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M14 family.
messages: Membrane
messages: secretory vesicle membrane

219594:TMEM216
gene id: 219594:TMEM216
uniprot id: A0A6J3D3V6
names: Subcellular Location Annotation
messages: Membrane

219594:LCMT1
gene id: 219594:LCMT1
uniprot id: A0A6J3DVU3
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily. LCMT family.
messages: Methylates the carboxyl group of the C-terminal leucine residue of protein phosphatase 2A catalytic subunits to form alpha-leucine ester residues.

219594:KPNA3
gene id: 219594:KPNA3
uniprot id: A0A6J3DF17
names: Similarity
messages: Belongs to the importin alpha family.

219594:NELL2
gene id: 219594:NELL2
uniprot id: A0A6J3EI80
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:NIPA1
gene id: 219594:NIPA1
uniprot id: A0A6J3ERR6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NIPA family.
messages: Membrane

219594:TDO2
gene id: 219594:TDO2
uniprot id: A0A6J3D1V2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tryptophan 2,3-dioxygenase family.
messages: Binds 1 heme group per subunit.
messages: Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L-tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety.
messages: Homotetramer. Dimer of dimers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:HSF1
gene id: 219594:HSF1
uniprot id: A0A6J3CKP6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HSF family.
messages: Nucleus

219594:MUSK
gene id: 219594:MUSK
uniprot id: A0A6J3EE67
uniprot id: A0A6J3EJ59
uniprot id: A0A6J3EJC8
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

219594:ORAI1
gene id: 219594:ORAI1
uniprot id: A0A6J3DV84
uniprot id: A0A6J3DZD4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Orai family.
messages: Membrane

219594:TSPAN32
gene id: 219594:TSPAN32
uniprot id: A0A6J3CZJ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

219594:FN3KRP
gene id: 219594:FN3KRP
uniprot id: A0A6J3DW43
names: Similarity
messages: Belongs to the fructosamine kinase family.

219594:PDC
gene id: 219594:PDC
uniprot id: A0A6J3DDF6
names: Similarity
messages: Belongs to the phosducin family.

219594:GORASP2
gene id: 219594:GORASP2
uniprot id: A0A6J3DAA0
names: Similarity
messages: Belongs to the GORASP family.

219594:LOC116500110
gene id: 219594:LOC116500110
uniprot id: A0A6J3EG67
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

219594:LOC116487562
gene id: 219594:LOC116487562
uniprot id: A0A6J3CQQ1
names: Similarity
messages: Belongs to the GST superfamily. Alpha family.

219594:SSX2IP
gene id: 219594:SSX2IP
uniprot id: A0A6J3DDT2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ADIP family.
messages: adherens junction
messages: centriolar satellite

219594:CRB1
gene id: 219594:CRB1
uniprot id: A0A6J3D9A3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:SH3BGRL
gene id: 219594:SH3BGRL
uniprot id: A0A6J3DR44
names: Similarity
messages: Belongs to the SH3BGR family.

219594:SLC17A9
gene id: 219594:SLC17A9
uniprot id: A0A6J3DX55
names: Subcellular Location Annotation
messages: Membrane

219594:LOC116495223
gene id: 219594:LOC116495223
uniprot id: A0A6J3DPQ9
uniprot id: A0A6J3DU12
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

219594:LOC116500316
gene id: 219594:LOC116500316
uniprot id: A0A6J3EBS1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

219594:LOC116486747
gene id: 219594:LOC116486747
uniprot id: A0A6J3CQB9
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily.

219594:SEMA4A
gene id: 219594:SEMA4A
uniprot id: A0A6J3E9F1
uniprot id: A0A6J3EEJ3
uniprot id: A0A6J3EG79
names: Caution
names: Similarity
messages: Belongs to the semaphorin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:LOC116501430
gene id: 219594:LOC116501430
uniprot id: A0A6J3ELZ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

219594:LOC116490628
gene id: 219594:LOC116490628
uniprot id: A0A6J3D617
names: Similarity
names: Subunit
messages: Belongs to the beta/gamma-crystallin family.
messages: Homo/heterodimer, or complexes of higher-order. The structure of beta-crystallin oligomers seems to be stabilized through interactions between the N-terminal arms.

219594:LOC116501331
gene id: 219594:LOC116501331
uniprot id: A0A6J3EHP1
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

219594:HNF4A
gene id: 219594:HNF4A
uniprot id: A0A6J3DUF9
uniprot id: A0A6J3DXE8
uniprot id: A0A6J3DYH3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

219594:SOAT1
gene id: 219594:SOAT1
uniprot id: A0A6J3DA80
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane-bound acyltransferase family. Sterol o-acyltransferase subfamily.
messages: Endoplasmic reticulum membrane
messages: Membrane

219594:ZMPSTE24
gene id: 219594:ZMPSTE24
uniprot id: A0A6J3EAC4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48A family.
messages: Binds 1 zinc ion per subunit.
messages: Endoplasmic reticulum membrane
messages: Proteolytically removes the C-terminal three residues of farnesylated proteins.

219594:SLC1A1
gene id: 219594:SLC1A1
uniprot id: A0A6J3EJP4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Membrane

219594:NEK8
gene id: 219594:NEK8
uniprot id: A0A6J3E3X4
names: Similarity
messages: Belongs to the protein kinase superfamily. NEK Ser/Thr protein kinase family. NIMA subfamily.

219594:FOXA1
gene id: 219594:FOXA1
uniprot id: A0A6J3D770
names: Subcellular Location Annotation
messages: Nucleus

219594:CACNA2D1
gene id: 219594:CACNA2D1
uniprot id: A0A6J3D3S2
uniprot id: A0A6J3D6E6
uniprot id: A0A6J3D6W1
uniprot id: A0A6J3D955
names: Similarity
messages: Belongs to the calcium channel subunit alpha-2/delta family.

219594:DYNC1I1
gene id: 219594:DYNC1I1
uniprot id: A0A6J3CD60
uniprot id: A0A6J3CES1
uniprot id: A0A6J3CES4
uniprot id: A0A6J3CFS6
uniprot id: A0A6J3CHN1
uniprot id: A0A6J3CJD9
names: Similarity
messages: Belongs to the dynein intermediate chain family.

219594:SEMA4G
gene id: 219594:SEMA4G
uniprot id: A0A6J3DB75
names: Caution
names: Similarity
messages: Belongs to the semaphorin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:IL10RB
gene id: 219594:IL10RB
uniprot id: A0A6J3EQU1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tissue factor family.
messages: Initiates blood coagulation by forming a complex with circulating factor VII or VIIa. The [TF:VIIa] complex activates factors IX or X by specific limited proteolysis. TF plays a role in normal hemostasis by initiating the cell-surface assembly and propagation of the coagulation protease cascade.
messages: Interacts with HSPE; the interaction, inhibited by heparin, promotes the generation of activated factor X and activates coagulation in the presence of activated factor VII.

219594:RSAD1
gene id: 219594:RSAD1
uniprot id: A0A6J3E1P4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: May be a heme chaperone, appears to bind heme. Homologous bacterial proteins do not have oxygen-independent coproporphyrinogen-III oxidase activity. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Mitochondrion

219594:CEBPZ
gene id: 219594:CEBPZ
uniprot id: A0A6J3CQW6
names: Similarity
messages: Belongs to the CBF/MAK21 family.

219594:ATP11C
gene id: 219594:ATP11C
uniprot id: A0A6J3DL44
uniprot id: A0A6J3DNJ3
uniprot id: A0A6J3DQD6
uniprot id: A0A6J3DQE0
uniprot id: A0A6J3DRG6
uniprot id: A0A6J3DSF1
uniprot id: A0A6J3DSF5
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

219594:ANTXRL
gene id: 219594:ANTXRL
uniprot id: A0A6J3DBL8
uniprot id: A0A6J3DC27
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATR family.
messages: Membrane

219594:LAMB1
gene id: 219594:LAMB1
uniprot id: A0A6J3CVX6
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: basement membrane

219594:HDDC2
gene id: 219594:HDDC2
uniprot id: A0A6J3CWT3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HDDC2 family.
messages: Catalyzes the dephosphorylation of the nucleoside 5'-monophosphates deoxyadenosine monophosphate (dAMP), deoxycytidine monophosphate (dCMP), deoxyguanosine monophosphate (dGMP) and deoxythymidine monophosphate (dTMP).
messages: Homodimer.

219594:LOC116491159
gene id: 219594:LOC116491159
uniprot id: A0A6J3DBV4
names: Similarity
messages: Belongs to the amidase family.

219594:LOC116486744
gene id: 219594:LOC116486744
uniprot id: A0A6J3CKT8
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily.

219594:ATP10A
gene id: 219594:ATP10A
uniprot id: A0A6J3DYN3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.
messages: Membrane

219594:LOC116501450
gene id: 219594:LOC116501450
uniprot id: A0A6J3EI85
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

219594:PCMT1
gene id: 219594:PCMT1
uniprot id: A0A6J3CRI3
uniprot id: A0A6J3CXQ3
names: Similarity
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.

219594:FN3K
gene id: 219594:FN3K
uniprot id: A0A6J3DWI8
names: Similarity
messages: Belongs to the fructosamine kinase family.

219594:ADAMTS2
gene id: 219594:ADAMTS2
uniprot id: A0A6J3DRJ9
names: Caution
names: Cofactor
names: Subcellular Location Annotation
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

219594:LOC116485639
gene id: 219594:LOC116485639
uniprot id: A0A6J3CJM9
names: Subcellular Location Annotation
messages: desmosome

219594:SLC22A3
gene id: 219594:SLC22A3
uniprot id: A0A6J3CPU5
names: Similarity
messages: Belongs to the major facilitator (TC 2.A.1) superfamily. Organic cation transporter (TC 2.A.1.19) family.

219594:TENM3
gene id: 219594:TENM3
uniprot id: A0A6J3CSH5
uniprot id: A0A6J3CSH9
uniprot id: A0A6J3CSI3
uniprot id: A0A6J3CUU2
uniprot id: A0A6J3CUU7
uniprot id: A0A6J3CV91
uniprot id: A0A6J3CV96
uniprot id: A0A6J3CXK3
uniprot id: A0A6J3CXL2
uniprot id: A0A6J3CXL7
uniprot id: A0A6J3CYN5
uniprot id: A0A6J3CYP2
uniprot id: A0A6J3CYP6
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tenascin family. Teneurin subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

219594:TSSC4
gene id: 219594:TSSC4
uniprot id: A0A6J3D1A5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TSSC4 family.
messages: Cytoplasm
messages: Nucleus

219594:FGF2
gene id: 219594:FGF2
uniprot id: A0A6J3CX03
names: Similarity
messages: Belongs to the heparin-binding growth factors family.

219594:CASP7
gene id: 219594:CASP7
uniprot id: A0A6J3DCJ5
names: Similarity
messages: Belongs to the peptidase C14A family.

219594:IRF7
gene id: 219594:IRF7
uniprot id: A0A6J3D3I5
names: Subcellular Location Annotation
messages: Nucleus

219594:GRK7
gene id: 219594:GRK7
uniprot id: A0A6J3DH65
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily.

219594:TFEC
gene id: 219594:TFEC
uniprot id: A0A6J3EH58
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MiT/TFE family.
messages: Nucleus

219594:DNAJB12
gene id: 219594:DNAJB12
uniprot id: A0A6J3DDH3
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

219594:LOC116501066
gene id: 219594:LOC116501066
uniprot id: A0A6J3EK66
names: Similarity
messages: Belongs to the G-alpha family. G(q) subfamily.

219594:BEND5
gene id: 219594:BEND5
uniprot id: A0A6J3DBH4
uniprot id: A0A6J3DCC7
uniprot id: A0A6J3DEF1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M14 family.
messages: cytosol

219594:TOMM5
gene id: 219594:TOMM5
uniprot id: A0A6J3EHZ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Tom5 family.
messages: Membrane
messages: Mitochondrion outer membrane

219594:DUSP1
gene id: 219594:DUSP1
uniprot id: A0A6J3DNN7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.
messages: Nucleus

219594:LOC116501389
gene id: 219594:LOC116501389
uniprot id: A0A6J3ELN1
names: Similarity
messages: Belongs to the G-alpha family. G(q) subfamily.

219594:CTC1
gene id: 219594:CTC1
uniprot id: A0A6J3EPN3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CTC1 family.
messages: Nucleus
messages: telomere

219594:LOC116500060
gene id: 219594:LOC116500060
uniprot id: A0A6J3EAY3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: nucleolus

219594:ONECUT1
gene id: 219594:ONECUT1
uniprot id: A0A6J3DNN1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CUT homeobox family.
messages: Nucleus

219594:SHROOM2
gene id: 219594:SHROOM2
uniprot id: A0A6J3CVX8
uniprot id: A0A6J3D1Y3
uniprot id: A0A6J3D202
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the shroom family.
messages: cytoskeleton

219594:SLC1A2
gene id: 219594:SLC1A2
uniprot id: A0A6J3D5P3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Membrane

219594:DAG1
gene id: 219594:DAG1
uniprot id: A0A6J3DEA4
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane
messages: The dystroglycan complex is involved in a number of processes including laminin and basement membrane assembly, sarcolemmal stability, cell survival, peripheral nerve myelination, nodal structure, cell migration, and epithelial polarization.
messages: Transmembrane protein that plays important roles in connecting the extracellular matrix to the cytoskeleton. Acts as a cell adhesion receptor in both muscle and non-muscle tissues. Receptor for both DMD and UTRN and, through these interactions, scaffolds axin to the cytoskeleton. Also functions in cell adhesion-mediated signaling and implicated in cell polarity.
messages: cytoskeleton
messages: extracellular space
messages: nucleoplasm
messages: sarcolemma

219594:SLC35D1
gene id: 219594:SLC35D1
uniprot id: A0A6J3DFH1
names: Subcellular Location Annotation
messages: Membrane

219594:FXN
gene id: 219594:FXN
uniprot id: A0A6J3EEZ5
names: Similarity
messages: Belongs to the frataxin family.

219594:SLC9A2
gene id: 219594:SLC9A2
uniprot id: A0A6J3E677
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Apical cell membrane
messages: Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.
messages: Cell membrane
messages: Interacts with CHP1 and CHP2.
messages: Membrane

219594:PROZ
gene id: 219594:PROZ
uniprot id: A0A6J3ER71
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:GSC2
gene id: 219594:GSC2
uniprot id: A0A6J3E0C5
names: Subcellular Location Annotation
messages: Nucleus

219594:PIK3CA
gene id: 219594:PIK3CA
uniprot id: A0A6J3DGX4
names: Similarity
messages: Belongs to the PI3/PI4-kinase family. Type III PI4K subfamily.

219594:HHIPL1
gene id: 219594:HHIPL1
uniprot id: A0A6J3D4Z3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:FAR2
gene id: 219594:FAR2
uniprot id: A0A6J3DVJ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fatty acyl-CoA reductase family.
messages: Catalyzes the reduction of fatty acyl-CoA to fatty alcohols.
messages: Peroxisome membrane

219594:ALKBH5
gene id: 219594:ALKBH5
uniprot id: A0A6J3DVN3
names: Subcellular Location Annotation
names: Subunit
messages: Monomer.
messages: Nucleus speckle

219594:ZDHHC13
gene id: 219594:ZDHHC13
uniprot id: A0A6J3CZ66
uniprot id: A0A6J3D1R0
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Cytoplasmic vesicle membrane
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

219594:SCARA5
gene id: 219594:SCARA5
uniprot id: A0A6J3CP90
uniprot id: A0A6J3CR83
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SCARA5 family.
messages: Cell membrane
messages: Ferritin receptor that mediates non-transferrin-dependent delivery of iron. Mediates cellular uptake of ferritin-bound iron by stimulating ferritin endocytosis from the cell surface with consequent iron delivery within the cell. Delivery of iron to cells by ferritin is required for the development of specific cell types, suggesting the existence of cell type-specific mechanisms of iron traffic in organogenesis, which alternatively utilize transferrin or non-transferrin iron delivery pathways.
messages: Homotrimer.
messages: Membrane

219594:LOC116497423
gene id: 219594:LOC116497423
uniprot id: A0A6J3E0G8
names: Similarity
messages: Belongs to the interleukin-1 receptor family.

219594:KCNMB2
gene id: 219594:KCNMB2
uniprot id: A0A6J3DG07
uniprot id: A0A6J3DH82
uniprot id: A0A6J3DIU6
names: Subcellular Location Annotation
messages: Membrane

219594:KRT18
gene id: 219594:KRT18
uniprot id: A0A6J3EAC2
names: Similarity
messages: Belongs to the intermediate filament family.

219594:RAB3IL1
gene id: 219594:RAB3IL1
uniprot id: A0A6J3D0F9
uniprot id: A0A6J3D2V4
uniprot id: A0A6J3D341
uniprot id: A0A6J3D6C1
names: Similarity
messages: Belongs to the SEC2 family.

219594:SLC16A12
gene id: 219594:SLC16A12
uniprot id: A0A6J3DAN9
uniprot id: A0A6J3DBE5
names: Subcellular Location Annotation
messages: Membrane

219594:IREB2
gene id: 219594:IREB2
uniprot id: A0A6J3DG58
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aconitase/IPM isomerase family.
messages: Cytoplasm

219594:ADNP
gene id: 219594:ADNP
uniprot id: A0A6J3DWU6
uniprot id: A0A6J3DXV5
names: Subcellular Location Annotation
messages: Nucleus

219594:PHACTR2
gene id: 219594:PHACTR2
uniprot id: A0A6J3CKM8
uniprot id: A0A6J3CM82
uniprot id: A0A6J3CNB1
uniprot id: A0A6J3CQI9
names: Similarity
names: Subunit
messages: Belongs to the phosphatase and actin regulator family.
messages: Binds PPP1CA and actin.

219594:PBX4
gene id: 219594:PBX4
uniprot id: A0A6J3EFS5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TALE/PBX homeobox family.
messages: Nucleus

219594:TSSK6
gene id: 219594:TSSK6
uniprot id: A0A6J3D7S9
names: Similarity
messages: Belongs to the protein kinase superfamily.

219594:ATP8A1
gene id: 219594:ATP8A1
uniprot id: A0A6J3CUB3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.
messages: Membrane

219594:GALNT5
gene id: 219594:GALNT5
uniprot id: A0A6J3D6Q9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
messages: Golgi apparatus membrane
messages: Membrane

219594:OPLAH
gene id: 219594:OPLAH
uniprot id: A0A6J3CM50
names: Similarity
messages: Belongs to the oxoprolinase family.

219594:LOC116488947
gene id: 219594:LOC116488947
uniprot id: A0A6J3D0W7
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

219594:DGKI
gene id: 219594:DGKI
uniprot id: A0A6J3DZH3
uniprot id: A0A6J3E0H1
names: Similarity
messages: Belongs to the eukaryotic diacylglycerol kinase family.

219594:RPS6KA1
gene id: 219594:RPS6KA1
uniprot id: A0A6J3E3L2
uniprot id: A0A6J3E8K4
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily.

219594:HMGCR
gene id: 219594:HMGCR
uniprot id: A0A6J3EC92
uniprot id: A0A6J3EHB0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HMG-CoA reductase family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Peroxisome membrane

219594:DIO1
gene id: 219594:DIO1
uniprot id: A0A6J3DCT5
names: Function
names: Similarity
messages: Belongs to the iodothyronine deiodinase family.
messages: Responsible for the deiodination of T4 (3,5,3',5'-tetraiodothyronine).

219594:LOC116489709
gene id: 219594:LOC116489709
uniprot id: A0A6J3D3R7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protease inhibitor I39 (alpha-2-macroglobulin) family.
messages: Secreted

219594:NTRK1
gene id: 219594:NTRK1
uniprot id: A0A6J3EGS6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. Insulin receptor subfamily.
messages: Membrane

219594:LVRN
gene id: 219594:LVRN
uniprot id: A0A6J3EF06
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M1 family.
messages: Binds 1 zinc ion per subunit.

219594:LOC116493112
gene id: 219594:LOC116493112
uniprot id: A0A6J3DF87
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sauvagine/corticotropin-releasing factor/urotensin I family.
messages: Binds with high affinity to CRF receptors 2-alpha and 2-beta.
messages: Secreted
messages: Suppresses food intake, delays gastric emptying and decreases heat-induced edema. Might represent an endogenous ligand for maintaining homeostasis after stress.

219594:ABCA1
gene id: 219594:ABCA1
uniprot id: A0A6J3EBX8
uniprot id: A0A6J3EGP3
names: Subcellular Location Annotation
messages: Membrane

219594:SLC15A5
gene id: 219594:SLC15A5
uniprot id: A0A6J3CU96
names: Similarity
messages: Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.

219594:IMPDH2
gene id: 219594:IMPDH2
uniprot id: A0A6J3DI83
uniprot id: A0A6J3DJI5
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.
messages: Nucleus

219594:ACYP1
gene id: 219594:ACYP1
uniprot id: A0A6J3CZF4
names: Similarity
messages: Belongs to the acylphosphatase family.

219594:HOXD9
gene id: 219594:HOXD9
uniprot id: A0A6J3D7G3
uniprot id: A0A6J3D7Y7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Abd-B homeobox family.
messages: Nucleus
messages: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

219594:LRWD1
gene id: 219594:LRWD1
uniprot id: A0A6J3E5D5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LRWD1 family.
messages: centrosome
messages: kinetochore
messages: telomere

219594:HPDL
gene id: 219594:HPDL
uniprot id: A0A6J3DAQ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4HPPD family.
messages: Catalyzes the conversion of 4-hydroxyphenylpyruvic acid to homogentisic acid, one of the steps in tyrosine catabolism.
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane

219594:LSM5
gene id: 219594:LSM5
uniprot id: A0A6J3CLB7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the snRNP Sm proteins family.
messages: LSm subunits form a heteromer with a doughnut shape.
messages: Nucleus
messages: Plays a role in U6 snRNP assembly and function. Binds to the 3' end of U6 snRNA.

219594:YWHAQ
gene id: 219594:YWHAQ
uniprot id: A0A6J3CSG8
names: Similarity
messages: Belongs to the 14-3-3 family.

219594:NDUFS1
gene id: 219594:NDUFS1
uniprot id: A0A6J3D7J9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I 75 kDa subunit family.
messages: Mitochondrion inner membrane

219594:AMZ1
gene id: 219594:AMZ1
uniprot id: A0A6J3DUT4
names: Function
names: Similarity
messages: Belongs to the peptidase M54 family.
messages: Probable zinc metalloprotease.

219594:RAF1
gene id: 219594:RAF1
uniprot id: A0A6J3DKK1
uniprot id: A0A6J3DL42
names: Similarity
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. RAF subfamily.

219594:MYO1B
gene id: 219594:MYO1B
uniprot id: A0A6J3D4V1
uniprot id: A0A6J3D808
uniprot id: A0A6J3D811
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.

219594:CLPS
gene id: 219594:CLPS
uniprot id: A0A6J3EAG9
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Colipase is a cofactor of pancreatic lipase. It allows the lipase to anchor itself to the lipid-water interface. Without colipase the enzyme is washed off by bile salts, which have an inhibitory effect on the lipase.
messages: Enterostatin has a biological activity as a satiety signal.
messages: Forms a 1:1 stoichiometric complex with pancreatic lipase.
messages: Secreted

219594:C2H5orf22
gene id: 219594:C2H5orf22
uniprot id: A0A6J3CPP7
names: Similarity
messages: Belongs to the UPF0489 family.

219594:FAM3D
gene id: 219594:FAM3D
uniprot id: A0A6J3DJ91
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAM3 family.
messages: Secreted

219594:SLC9A1
gene id: 219594:SLC9A1
uniprot id: A0A6J3E809
names: Similarity
names: Subcellular Location Annotation
messages: Basolateral cell membrane
messages: Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.
messages: Cell membrane
messages: Lateral cell membrane
messages: Membrane

219594:SERPINE3
gene id: 219594:SERPINE3
uniprot id: A0A6J3EFG8
names: Similarity
messages: Belongs to the serpin family.

219594:ADORA2A
gene id: 219594:ADORA2A
uniprot id: A0A6J3DWQ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase.

219594:CUTC
gene id: 219594:CUTC
uniprot id: A0A6J3D716
uniprot id: A0A6J3DD00
names: Similarity
messages: Belongs to the CutC family.

219594:REEP5
gene id: 219594:REEP5
uniprot id: A0A6J3EJ92
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DP1 family.
messages: Membrane

219594:IER5
gene id: 219594:IER5
uniprot id: A0A6J3DG41
names: Similarity
messages: Belongs to the IER family.

219594:TCF7
gene id: 219594:TCF7
uniprot id: A0A6J3DU13
uniprot id: A0A6J3DUV8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TCF/LEF family.
messages: Nucleus

219594:SEPHS1
gene id: 219594:SEPHS1
uniprot id: A0A6J3EI55
names: Function
messages: Synthesizes selenophosphate from selenide and ATP.

219594:UNC13C
gene id: 219594:UNC13C
uniprot id: A0A6J3DM66
uniprot id: A0A6J3DMR1
names: Subcellular Location Annotation
messages: Cytoplasm

219594:USP22
gene id: 219594:USP22
uniprot id: A0A6J3DP26
uniprot id: A0A6J3DTC3
names: Similarity
messages: Belongs to the peptidase C19 family.

219594:LRP8
gene id: 219594:LRP8
uniprot id: A0A6J3DFA7
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:EGFLAM
gene id: 219594:EGFLAM
uniprot id: A0A6J3EGA9
uniprot id: A0A6J3EJY1
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:PPP2R3C
gene id: 219594:PPP2R3C
uniprot id: A0A6J3D6G6
uniprot id: A0A6J3D7C1
names: Subcellular Location Annotation
messages: Nucleus

219594:LOC116498690
gene id: 219594:LOC116498690
uniprot id: A0A6J3EA02
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

219594:TMCC3
gene id: 219594:TMCC3
uniprot id: A0A6J3DI97
uniprot id: A0A6J3DJH9
uniprot id: A0A6J3DL29
names: Similarity
messages: Belongs to the TEX28 family.

219594:IKBKB
gene id: 219594:IKBKB
uniprot id: A0A6J3E9T8
uniprot id: A0A6J3EF40
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

219594:CDC25A
gene id: 219594:CDC25A
uniprot id: A0A6J3CIU8
names: Function
names: Similarity
messages: Belongs to the MPI phosphatase family.
messages: Functions as a dosage-dependent inducer in mitotic control. Tyrosine protein phosphatase required for progression of the cell cycle.

219594:VAMP5
gene id: 219594:VAMP5
uniprot id: A0A6J3EA88
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptobrevin family.
messages: Membrane

219594:SLC37A3
gene id: 219594:SLC37A3
uniprot id: A0A6J3DUG9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Organophosphate:Pi antiporter (OPA) (TC 2.A.1.4) family.
messages: Membrane

219594:ATG4C
gene id: 219594:ATG4C
uniprot id: A0A6J3DG28
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C54 family.
messages: Cysteine protease that plays a key role in autophagy by mediating both proteolytic activation and delipidation of ATG8 family proteins.
messages: Cytoplasm

219594:SLC26A11
gene id: 219594:SLC26A11
uniprot id: A0A6J3DVY7
uniprot id: A0A6J3E049
uniprot id: A0A6J3E0Y2
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

219594:INHBB
gene id: 219594:INHBB
uniprot id: A0A6J3D711
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TGF-beta family.
messages: Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition. Inhibins appear to oppose the functions of activins.
messages: Secreted

219594:GTF2H5
gene id: 219594:GTF2H5
uniprot id: A0A6J3CSS6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TFB5 family.
messages: Component of the 7-subunit TFIIH core complex.
messages: In NER, TFIIH acts by opening DNA around the lesion to allow the excision of the damaged oligonucleotide and its replacement by a new DNA fragment. In transcription, TFIIH has an essential role in transcription initiation. When the pre-initiation complex (PIC) has been established, TFIIH is required for promoter opening and promoter escape.
messages: Nucleus

219594:RPS6KA6
gene id: 219594:RPS6KA6
uniprot id: A0A6J3DPM0
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily.

219594:NCBP1
gene id: 219594:NCBP1
uniprot id: A0A6J3EHT4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NCBP1 family.
messages: Nucleus

219594:TECR
gene id: 219594:TECR
uniprot id: A0A6J3D8E0
uniprot id: A0A6J3DB43
uniprot id: A0A6J3DBZ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the steroid 5-alpha reductase family.
messages: Endoplasmic reticulum membrane
messages: Membrane

219594:CRYL1
gene id: 219594:CRYL1
uniprot id: A0A6J3EDB8
names: Similarity
messages: Belongs to the 3-hydroxyacyl-CoA dehydrogenase family.

219594:TRDN
gene id: 219594:TRDN
uniprot id: A0A6J3CTX0
names: Subcellular Location Annotation
messages: Membrane
messages: Sarcoplasmic reticulum membrane

219594:LOC116495907
gene id: 219594:LOC116495907
uniprot id: A0A6J3DV02
names: Similarity
messages: Belongs to the FAM83 family.

219594:RTRAF
gene id: 219594:RTRAF
uniprot id: A0A6J3CZR0
names: Similarity
messages: Belongs to the RTRAF family.

219594:DCTN6
gene id: 219594:DCTN6
uniprot id: A0A6J3CYS7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dynactin subunits 5/6 family. Dynactin subunit 6 subfamily.
messages: Part of the dynactin complex that activates the molecular motor dynein for ultra-processive transport along microtubules.
messages: cytoskeleton

219594:EMX2
gene id: 219594:EMX2
uniprot id: A0A6J3DE01
names: Subcellular Location Annotation
messages: Nucleus

219594:EXOSC1
gene id: 219594:EXOSC1
uniprot id: A0A6J3DA84
uniprot id: A0A6J3DAY0
uniprot id: A0A6J3DD49
uniprot id: A0A6J3DDH7
names: Subcellular Location Annotation
messages: Cytoplasm

219594:CNDP2
gene id: 219594:CNDP2
uniprot id: A0A6J3CH38
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M20A family.
messages: Binds 2 manganese ions per subunit.

219594:VEGFC
gene id: 219594:VEGFC
uniprot id: A0A6J3D0F8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PDGF/VEGF growth factor family.
messages: Secreted

219594:SLC7A2
gene id: 219594:SLC7A2
uniprot id: A0A6J3D0D7
uniprot id: A0A6J3D1I9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Cationic amino acid transporter (CAT) (TC 2.A.3.3) family.
messages: Cell membrane
messages: Membrane

219594:LOC116500341
gene id: 219594:LOC116500341
uniprot id: A0A6J3EIF1
names: Subcellular Location Annotation
messages: Membrane

219594:PITPNM1
gene id: 219594:PITPNM1
uniprot id: A0A6J3D108
names: Similarity
messages: Belongs to the PtdIns transfer protein family. PI transfer class IIA subfamily.

219594:DYNC1I2
gene id: 219594:DYNC1I2
uniprot id: A0A6J3D388
uniprot id: A0A6J3D5S6
uniprot id: A0A6J3D931
names: Similarity
messages: Belongs to the dynein intermediate chain family.

219594:CMTM3
gene id: 219594:CMTM3
uniprot id: A0A6J3DQF6
names: Subcellular Location Annotation
messages: Membrane

219594:THAP1
gene id: 219594:THAP1
uniprot id: A0A6J3ELY0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the THAP1 family.
messages: DNA-binding transcription regulator that regulates endothelial cell proliferation and G1/S cell-cycle progression. Specifically binds the 5'-[AT]NTNN[GT]GGCA[AGT]-3' core DNA sequence and acts by modulating expression of pRB-E2F cell-cycle target genes.
messages: nucleoplasm

219594:LOC116487373
gene id: 219594:LOC116487373
uniprot id: A0A6J3CTA3
names: Similarity
messages: Belongs to the actin family.

219594:PPP3R1
gene id: 219594:PPP3R1
uniprot id: A0A6J3CSE4
names: Similarity
messages: Belongs to the calcineurin regulatory subunit family.

219594:SLC51A
gene id: 219594:SLC51A
uniprot id: A0A6J3DBC1
names: Subcellular Location Annotation
messages: Membrane

219594:ERGIC1
gene id: 219594:ERGIC1
uniprot id: A0A6J3DRL4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ERGIC family.
messages: Endoplasmic reticulum membrane
messages: Endoplasmic reticulum-Golgi intermediate compartment membrane
messages: Golgi apparatus membrane
messages: Plays a role in transport between endoplasmic reticulum and Golgi.

219594:GNA12
gene id: 219594:GNA12
uniprot id: A0A6J3DUB4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-alpha family. G(12) subfamily.
messages: Membrane

219594:TMEM30A
gene id: 219594:TMEM30A
uniprot id: A0A6J3CK79
names: Similarity
messages: Belongs to the CDC50/LEM3 family.

219594:HPSE2
gene id: 219594:HPSE2
uniprot id: A0A6J3D9F2
names: Similarity
messages: Belongs to the glycosyl hydrolase 79 family.

219594:AP4S1
gene id: 219594:AP4S1
uniprot id: A0A6J3D3R9
names: Similarity
messages: Belongs to the adaptor complexes small subunit family.

219594:PGAP2
gene id: 219594:PGAP2
uniprot id: A0A6J3DT29
uniprot id: A0A6J3DT51
uniprot id: A0A6J3DW35
uniprot id: A0A6J3DWZ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PGAP2 family.
messages: Involved in the lipid remodeling steps of GPI-anchor maturation. Required for stable expression of GPI-anchored proteins at the cell surface.
messages: Membrane

219594:DENND5B
gene id: 219594:DENND5B
uniprot id: A0A6J3DKF1
names: Caution
names: Similarity
messages: Belongs to the RAB6IP1 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:SAMD4A
gene id: 219594:SAMD4A
uniprot id: A0A6J3D5Q6
uniprot id: A0A6J3D6L7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SMAUG family.
messages: Cytoplasm

219594:EFHC2
gene id: 219594:EFHC2
uniprot id: A0A6J3EMB6
uniprot id: A0A6J3EMC8
names: Subcellular Location Annotation
messages: cilium axoneme

219594:VIM
gene id: 219594:VIM
uniprot id: A0A6J3CK02
names: Similarity
messages: Belongs to the intermediate filament family.

219594:PAQR3
gene id: 219594:PAQR3
uniprot id: A0A6J3CYD5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ADIPOR family.
messages: Membrane

219594:MRPL18
gene id: 219594:MRPL18
uniprot id: A0A6J3CUT9
names: Similarity
messages: Belongs to the universal ribosomal protein uL18 family.

219594:MINDY1
gene id: 219594:MINDY1
uniprot id: A0A6J3E9T9
names: Function
names: Similarity
messages: Belongs to the MINDY deubiquitinase family. FAM63 subfamily.
messages: Hydrolase that can specifically remove 'Lys-48'-linked conjugated ubiquitin from proteins. Has exodeubiquitinase activity and has a preference for long polyubiquitin chains. May play a regulatory role at the level of protein turnover.

219594:MAP7D2
gene id: 219594:MAP7D2
uniprot id: A0A6J3D2J7
uniprot id: A0A6J3D2L5
uniprot id: A0A6J3D5C3
uniprot id: A0A6J3D5G0
uniprot id: A0A6J3D7P7
uniprot id: A0A6J3D8G7
names: Similarity
messages: Belongs to the MAP7 family.

219594:LOC116500928
gene id: 219594:LOC116500928
uniprot id: A0A6J3EG24
names: Similarity
messages: Belongs to the calycin superfamily. Lipocalin family.

219594:TAT
gene id: 219594:TAT
uniprot id: A0A6J3DNV0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.
messages: Transaminase involved in tyrosine breakdown. Converts tyrosine to p-hydroxyphenylpyruvate.

219594:GAR1
gene id: 219594:GAR1
uniprot id: A0A6J3D1B1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GAR1 family.
messages: Component of the small nucleolar ribonucleoprotein particles containing H/ACA-type snoRNAs (H/ACA snoRNPs).
messages: Required for ribosome biogenesis. Part of a complex which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Pseudouridine ("psi") residues may serve to stabilize the conformation of rRNAs.
messages: nucleolus

219594:FGF8
gene id: 219594:FGF8
uniprot id: A0A6J3DC88
names: Similarity
messages: Belongs to the heparin-binding growth factors family.

219594:KIAA1324
gene id: 219594:KIAA1324
uniprot id: A0A6J3EAH0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELAPOR family.
messages: Cell membrane
messages: Membrane

219594:DDX49
gene id: 219594:DDX49
uniprot id: A0A6J3E9E7
names: Similarity
messages: Belongs to the DEAD box helicase family.

219594:PGGT1B
gene id: 219594:PGGT1B
uniprot id: A0A6J3EF15
names: Similarity
messages: Belongs to the protein prenyltransferase subunit beta family.

219594:ATP23
gene id: 219594:ATP23
uniprot id: A0A6J3DJ62
names: Similarity
messages: Belongs to the peptidase M76 family.

219594:POLR3F
gene id: 219594:POLR3F
uniprot id: A0A6J3CQV8
uniprot id: A0A6J3CT64
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic RPC34/RPC39 RNA polymerase subunit family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs.
messages: Nucleus

219594:LOC116494364
gene id: 219594:LOC116494364
uniprot id: A0A6J3DR89
uniprot id: A0A6J3DS67
names: Similarity
messages: Belongs to the EVA1 family.

219594:LOC116501300
gene id: 219594:LOC116501300
uniprot id: A0A6J3ELD2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

219594:GEMIN2
gene id: 219594:GEMIN2
uniprot id: A0A6J3D1C1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the gemin-2 family.
messages: Cytoplasm
messages: Part of the core SMN complex.
messages: The SMN complex catalyzes the assembly of small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome, and thereby plays an important role in the splicing of cellular pre-mRNAs.

219594:LOC116486316
gene id: 219594:LOC116486316
uniprot id: A0A6J3CIQ0
names: Similarity
messages: Belongs to the serpin family.

219594:MASP1
gene id: 219594:MASP1
uniprot id: A0A6J3DGC0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:STUM
gene id: 219594:STUM
uniprot id: A0A6J3CKD1
names: Subcellular Location Annotation
messages: Membrane

219594:FTO
gene id: 219594:FTO
uniprot id: A0A6J3DM29
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fto family.
messages: Cytoplasm
messages: Nucleus speckle

219594:LOC116500389
gene id: 219594:LOC116500389
uniprot id: A0A6J3EH23
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alpha/beta interferon family.
messages: Has antiviral activities.
messages: Secreted

219594:LOC116500503
gene id: 219594:LOC116500503
uniprot id: A0A6J3EHG2
names: Function
names: Similarity
messages: Belongs to the alpha-carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

219594:LOC116494512
gene id: 219594:LOC116494512
uniprot id: A0A6J3DNV2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

219594:MEIS1
gene id: 219594:MEIS1
uniprot id: A0A6J3CRC6
uniprot id: A0A6J3CTL4
uniprot id: A0A6J3CUR0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TALE/MEIS homeobox family.
messages: Nucleus

219594:LOC116497559
gene id: 219594:LOC116497559
uniprot id: A0A6J3E2D1
uniprot id: A0A6J3E742
names: Similarity
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.

219594:PPIL2
gene id: 219594:PPIL2
uniprot id: A0A6J3DZI4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cyclophilin-type PPIase family. PPIL2 subfamily.
messages: Nucleus

219594:LOC116486463
gene id: 219594:LOC116486463
uniprot id: A0A6J3CP33
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

219594:LOC116493946
gene id: 219594:LOC116493946
uniprot id: A0A6J3DPN0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the p22phox family.
messages: Cell membrane
messages: Composed of a heavy chain (beta) and a light chain (alpha). Component of an NADPH oxidase complex composed of a heterodimer formed by the membrane proteins CYBA and CYBB and the cytosolic subunits NCF1, NCF2 and NCF4. Interacts with NCF1 (via SH3 domain).
messages: Critical component of the membrane-bound oxidase of phagocytes that generates superoxide. Associates with NOX3 to form a functional NADPH oxidase constitutively generating superoxide.
messages: Membrane

219594:MALRD1
gene id: 219594:MALRD1
uniprot id: A0A6J3CI88
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:SERPINF2
gene id: 219594:SERPINF2
uniprot id: A0A6J3E475
names: Similarity
messages: Belongs to the serpin family.

219594:CTDP1
gene id: 219594:CTDP1
uniprot id: A0A6J3CJR7
names: Function
names: Subcellular Location Annotation
messages: Nucleus
messages: This promotes the activity of RNA polymerase II.

219594:FLI1
gene id: 219594:FLI1
uniprot id: A0A6J3E2M9
uniprot id: A0A6J3E427
uniprot id: A0A6J3E6X6
uniprot id: A0A6J3E7M2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

219594:NR1H4
gene id: 219594:NR1H4
uniprot id: A0A6J3EIM8
uniprot id: A0A6J3ENV3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR1 subfamily.
messages: Nuclear hormone receptor that can act as a repressor or activator of transcription. High affinity receptor for thyroid hormones, including triiodothyronine and thyroxine.
messages: Nucleus

219594:PRNP
gene id: 219594:PRNP
uniprot id: A0A6J3E9U6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prion family.
messages: Cell membrane
messages: Membrane

219594:PLA2G15
gene id: 219594:PLA2G15
uniprot id: A0A6J3DQC6
names: Similarity
messages: Belongs to the AB hydrolase superfamily. Lipase family.

219594:ITPKA
gene id: 219594:ITPKA
uniprot id: A0A6J3D0C3
names: Similarity
messages: Belongs to the inositol phosphokinase (IPK) family.

219594:AMN
gene id: 219594:AMN
uniprot id: A0A6J3D4T9
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

219594:LOC116499903
gene id: 219594:LOC116499903
uniprot id: A0A6J3EFF4
names: Similarity
messages: Belongs to the intermediate filament family.

219594:USP39
gene id: 219594:USP39
uniprot id: A0A6J3EEZ0
names: Subcellular Location Annotation
messages: Nucleus

219594:LOC116493636
gene id: 219594:LOC116493636
uniprot id: A0A6J3DLY8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: A cytochrome P450 monooxygenase that catalyzes the side-chain hydroxylation and cleavage of cholesterol to pregnenolone, the precursor of most steroid hormones. Catalyzes three sequential oxidation reactions of cholesterol, namely the hydroxylation at C22 followed with the hydroxylation at C20 to yield 20R,22R-hydroxycholesterol that is further cleaved between C20 and C22 to yield the C21-steroid pregnenolone and 4-methylpentanal. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate and reducing the second into a water molecule. Two electrons are provided by NADPH via a two-protein mitochondrial transfer system comprising flavoprotein FDXR (adrenodoxin/ferredoxin reductase) and nonheme iron-sulfur protein FDX1 or FDX2 (adrenodoxin/ferredoxin).
messages: Belongs to the cytochrome P450 family.
messages: Mitochondrion inner membrane

219594:SPAM1
gene id: 219594:SPAM1
uniprot id: A0A6J3E919
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 56 family.
messages: Cell membrane
messages: Membrane

219594:CPM
gene id: 219594:CPM
uniprot id: A0A6J3DNI9
names: Similarity
messages: Belongs to the peptidase M14 family.

219594:CHMP2B
gene id: 219594:CHMP2B
uniprot id: A0A6J3E5I4
names: Similarity
messages: Belongs to the SNF7 family.

219594:SIAH3
gene id: 219594:SIAH3
uniprot id: A0A6J3EQU7
names: Domain
names: Function
names: Similarity
messages: Belongs to the SINA (Seven in absentia) family.
messages: E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.
messages: The RING-type zinc finger domain is essential for ubiquitin ligase activity.
messages: The SBD domain (substrate-binding domain) mediates the interaction with substrate proteins. It is related to the TRAF family.

219594:HSP90AB1
gene id: 219594:HSP90AB1
uniprot id: A0A6J3CMN0
names: Similarity
messages: Belongs to the heat shock protein 90 family.

219594:GREB1
gene id: 219594:GREB1
uniprot id: A0A6J3CXE9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GREB1 family.
messages: Membrane

219594:SV2C
gene id: 219594:SV2C
uniprot id: A0A6J3EJ38
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily.
messages: Membrane
messages: synaptic vesicle membrane

219594:SLC4A7
gene id: 219594:SLC4A7
uniprot id: A0A6J3CLK7
uniprot id: A0A6J3CMR7
uniprot id: A0A6J3CPW2
names: Similarity
names: Subcellular Location Annotation
messages: Basolateral cell membrane
messages: Belongs to the anion exchanger (TC 2.A.31) family.
messages: Cell membrane
messages: Lateral cell membrane
messages: Membrane

219594:LOC116500499
gene id: 219594:LOC116500499
uniprot id: A0A6J3EHF8
names: Similarity
messages: Belongs to the avidin/streptavidin family.

219594:LSS
gene id: 219594:LSS
uniprot id: A0A6J3D9E6
names: Similarity
messages: Belongs to the terpene cyclase/mutase family.

219594:DLK2
gene id: 219594:DLK2
uniprot id: A0A6J3CQY1
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:LOC116501423
gene id: 219594:LOC116501423
uniprot id: A0A6J3EGK5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

219594:TRIP12
gene id: 219594:TRIP12
uniprot id: A0A6J3DCW3
uniprot id: A0A6J3DFK7
uniprot id: A0A6J3DIE7
uniprot id: A0A6J3DIF3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPL family. K-HECT subfamily.
messages: E3 ubiquitin-protein ligase involved in ubiquitin fusion degradation (UFD) pathway and regulation of DNA repair. Part of the ubiquitin fusion degradation (UFD) pathway, a process that mediates ubiquitination of protein at their N-terminus, regardless of the presence of lysine residues in target proteins.
messages: nucleoplasm

219594:LOC116501357
gene id: 219594:LOC116501357
uniprot id: A0A6J3EHR7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

219594:LEO1
gene id: 219594:LEO1
uniprot id: A0A6J3DKG9
uniprot id: A0A6J3DM05
names: Similarity
messages: Belongs to the LEO1 family.

219594:BRPF1
gene id: 219594:BRPF1
uniprot id: A0A6J3DFL7
uniprot id: A0A6J3DL68
names: Subcellular Location Annotation
messages: Nucleus

219594:LOC116499798
gene id: 219594:LOC116499798
uniprot id: A0A6J3EBF5
names: Similarity
names: Subunit
messages: Belongs to the avian keratin family.
messages: The avian keratins (F-ker, S-ker, C-ker and B-ker) are a complex mixture of very similar polypeptides.

219594:MYO5A
gene id: 219594:MYO5A
uniprot id: A0A6J3DK76
uniprot id: A0A6J3DLQ0
uniprot id: A0A6J3DN42
uniprot id: A0A6J3DNR6
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.

219594:CHM
gene id: 219594:CHM
uniprot id: A0A6J3DQ05
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Rab GDI family.
messages: Cytoplasm
messages: Substrate-binding subunit (component A) of the Rab geranylgeranyltransferase (GGTase) complex. Binds unprenylated Rab proteins and presents the substrate peptide to the catalytic component B. The component A is thought to be regenerated by transferring its prenylated Rab back to the donor membrane.

219594:KIZ
gene id: 219594:KIZ
uniprot id: A0A6J3CKL9
uniprot id: A0A6J3CM71
uniprot id: A0A6J3CNA1
uniprot id: A0A6J3CRK0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the kizuna family.
messages: Centrosomal protein required for establishing a robust mitotic centrosome architecture that can endure the forces that converge on the centrosomes during spindle formation. Required for stabilizing the expanded pericentriolar material around the centriole.
messages: centrosome
messages: cilium basal body

219594:FGFR3
gene id: 219594:FGFR3
uniprot id: A0A6J3CTF3
uniprot id: A0A6J3CYI6
uniprot id: A0A6J3CZK5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. Fibroblast growth factor receptor subfamily.
messages: Cell membrane
messages: Membrane

219594:WDFY2
gene id: 219594:WDFY2
uniprot id: A0A6J3EKP4
names: Subcellular Location Annotation
messages: Early endosome
messages: Endosome

219594:TXNL4A
gene id: 219594:TXNL4A
uniprot id: A0A6J3CKN2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DIM1 family.
messages: Nucleus
messages: Plays role in pre-mRNA splicing.

219594:SLC4A11
gene id: 219594:SLC4A11
uniprot id: A0A6J3CVJ8
uniprot id: A0A6J3CW02
uniprot id: A0A6J3CYC0
uniprot id: A0A6J3CZE1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anion exchanger (TC 2.A.31) family.
messages: Cell membrane
messages: Membrane

219594:LOC116493125
gene id: 219594:LOC116493125
uniprot id: A0A6J3DKU3
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M10A family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Can bind about 5 Ca(2+) ions per subunit.

219594:BRINP3
gene id: 219594:BRINP3
uniprot id: A0A6J3DGQ2
names: Similarity
messages: Belongs to the BRINP family.

219594:MYO18A
gene id: 219594:MYO18A
uniprot id: A0A6J3DYU1
uniprot id: A0A6J3E0G1
uniprot id: A0A6J3E339
uniprot id: A0A6J3E3W9
uniprot id: A0A6J3E4X3
uniprot id: A0A6J3E4X9
names: Caution
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:SUGCT
gene id: 219594:SUGCT
uniprot id: A0A6J3CJ48
uniprot id: A0A6J3CLT1
uniprot id: A0A6J3CNR0
names: Similarity
messages: Belongs to the CoA-transferase III family.

219594:IL17REL
gene id: 219594:IL17REL
uniprot id: A0A6J3DZ21
names: Subcellular Location Annotation
messages: Cell membrane

219594:GAREM1
gene id: 219594:GAREM1
uniprot id: A0A6J3CCY1
uniprot id: A0A6J3CEI9
names: Similarity
messages: Belongs to the GAREM family.

219594:PDHA1
gene id: 219594:PDHA1
uniprot id: A0A6J3EG30
names: Function
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2), and thereby links the glycolytic pathway to the tricarboxylic cycle.

219594:PVALB
gene id: 219594:PVALB
uniprot id: A0A6J3E4G7
names: Function
names: Similarity
messages: Belongs to the parvalbumin family.
messages: In muscle, parvalbumin is thought to be involved in relaxation after contraction. It binds two calcium ions.

219594:DDIT4
gene id: 219594:DDIT4
uniprot id: A0A6J3D773
names: Similarity
messages: Belongs to the DDIT4 family.

219594:SCD
gene id: 219594:SCD
uniprot id: A0A6J3DC37
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fatty acid desaturase type 1 family.
messages: Membrane
messages: The histidine box domains are involved in binding the catalytic metal ions.

219594:TRDMT1
gene id: 219594:TRDMT1
uniprot id: A0A6J3CHY7
uniprot id: A0A6J3CIZ5
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.

219594:GRP
gene id: 219594:GRP
uniprot id: A0A6J3EKT8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bombesin/neuromedin-B/ranatensin family.
messages: Secreted

219594:LOC116489994
gene id: 219594:LOC116489994
uniprot id: A0A6J3D558
names: Similarity
messages: Belongs to the serpin family.

219594:ARHGEF12
gene id: 219594:ARHGEF12
uniprot id: A0A6J3E3H0
uniprot id: A0A6J3E726
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Membrane

219594:SUOX
gene id: 219594:SUOX
uniprot id: A0A6J3EBL9
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the oxidation of sulfite to sulfate, the terminal reaction in the oxidative degradation of sulfur-containing amino acids.
messages: Homodimer.
messages: Mitochondrion intermembrane space

219594:HADH
gene id: 219594:HADH
uniprot id: A0A6J3D0V7
names: Similarity
messages: Belongs to the 3-hydroxyacyl-CoA dehydrogenase family.

219594:LOC116486853
gene id: 219594:LOC116486853
uniprot id: A0A6J3CM85
names: Similarity
names: Subunit
messages: Belongs to the avian keratin family.
messages: The avian keratins (F-ker, S-ker, C-ker and B-ker) are a complex mixture of very similar polypeptides.

219594:LOC116491597
gene id: 219594:LOC116491597
uniprot id: A0A6J3D843
uniprot id: A0A6J3DE29
names: Similarity
messages: Belongs to the AB hydrolase superfamily. Lipase family.

219594:SGK1
gene id: 219594:SGK1
uniprot id: A0A6J3CPF7
uniprot id: A0A6J3CRF9
names: Similarity
messages: Belongs to the protein kinase superfamily.

219594:SH3BP5
gene id: 219594:SH3BP5
uniprot id: A0A6J3CNY8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SH3BP5 family.
messages: Cytoplasm
messages: Functions as guanine nucleotide exchange factor (GEF) for RAB11A.
messages: Interacts with GDP-bound and nucleotide-free forms of RAB11A.
messages: The N-terminal half of the protein mediates interaction with RAB11A and functions as guanine nucleotide exchange factor. Four long alpha-helices (interrupted by a central kink) assemble into coiled coils, giving rise to a 'V' shape.

219594:ACTG2
gene id: 219594:ACTG2
uniprot id: A0A6J3EA28
names: Similarity
messages: Belongs to the actin family.

219594:LOC116499891
gene id: 219594:LOC116499891
uniprot id: A0A6J3EBQ4
uniprot id: A0A6J3EF21
uniprot id: A0A6J3EFE0
uniprot id: A0A6J3EH16
names: Similarity
messages: Belongs to the intermediate filament family.

219594:PHF19
gene id: 219594:PHF19
uniprot id: A0A6J3DYD4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Polycomblike family.
messages: Nucleus

219594:LOC116497231
gene id: 219594:LOC116497231
uniprot id: A0A6J3E3S0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat SEC13 family.
messages: Lysosome membrane

219594:TMED4
gene id: 219594:TMED4
uniprot id: A0A6J3E8P1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EMP24/GP25L family.
messages: Endoplasmic reticulum membrane
messages: Membrane

219594:LOC116501314
gene id: 219594:LOC116501314
uniprot id: A0A6J3EMV0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

219594:LOC116500150
gene id: 219594:LOC116500150
uniprot id: A0A6J3EFZ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

219594:CDC37L1
gene id: 219594:CDC37L1
uniprot id: A0A6J3EI28
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDC37 family.
messages: Cytoplasm

219594:LOC116485679
gene id: 219594:LOC116485679
uniprot id: A0A6J3CF57
names: Similarity
messages: Belongs to the avian keratin family.

219594:FOXI3
gene id: 219594:FOXI3
uniprot id: A0A6J3D064
names: Subcellular Location Annotation
messages: Nucleus

219594:LOC116486219
gene id: 219594:LOC116486219
uniprot id: A0A6J3CMV6
names: Similarity
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.

219594:TMEM177
gene id: 219594:TMEM177
uniprot id: A0A6J3DB64
names: Function
names: Similarity
messages: Belongs to the TMEM177 family.
messages: Plays a role in the early steps of cytochrome c oxidase subunit II (MT-CO2/COX2) maturation and is required for the stabilization of COX20 and the newly synthesized MT-CO2/COX2 protein.

219594:NIPA2
gene id: 219594:NIPA2
uniprot id: A0A6J3EJK5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NIPA family.
messages: Membrane

219594:ARHGEF6
gene id: 219594:ARHGEF6
uniprot id: A0A6J3DN53
uniprot id: A0A6J3DPY0
uniprot id: A0A6J3DRY9
names: Subcellular Location Annotation
messages: lamellipodium

219594:ARHGEF3
gene id: 219594:ARHGEF3
uniprot id: A0A6J3DEY0
uniprot id: A0A6J3DHM8
uniprot id: A0A6J3DKI4
uniprot id: A0A6J3DL28
names: Function
names: Subcellular Location Annotation
messages: Acts as guanine nucleotide exchange factor (GEF) for RhoA and RhoB GTPases.
messages: Cytoplasm

219594:TPPP
gene id: 219594:TPPP
uniprot id: A0A6J3CGF2
names: Similarity
messages: Belongs to the TPPP family.

219594:ASPN
gene id: 219594:ASPN
uniprot id: A0A6J3DE31
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class I subfamily.
messages: extracellular matrix

219594:XPO7
gene id: 219594:XPO7
uniprot id: A0A6J3EDK2
uniprot id: A0A6J3EF96
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exportin family.
messages: Cytoplasm
messages: Nucleus

219594:ANPEP
gene id: 219594:ANPEP
uniprot id: A0A6J3DPE3
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M1 family.
messages: Binds 1 zinc ion per subunit.

219594:RYBP
gene id: 219594:RYBP
uniprot id: A0A6J3DHL8
names: Subcellular Location Annotation
messages: Nucleus

219594:ARGLU1
gene id: 219594:ARGLU1
uniprot id: A0A6J3CWY1
names: Similarity
messages: Belongs to the UPF0430 family.

219594:KCNK1
gene id: 219594:KCNK1
uniprot id: A0A6J3CNP5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
messages: Cell membrane
messages: Cytoplasmic vesicle
messages: Endosome
messages: Membrane
messages: Perikaryon
messages: Recycling endosome
messages: Synaptic cell membrane
messages: Vesicle
messages: dendrite

219594:LOC116502185
gene id: 219594:LOC116502185
uniprot id: A0A6J3EKN7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

219594:FGF13
gene id: 219594:FGF13
uniprot id: A0A6J3DLR3
uniprot id: A0A6J3DR05
names: Similarity
messages: Belongs to the heparin-binding growth factors family.

219594:LOC116486524
gene id: 219594:LOC116486524
uniprot id: A0A6J3CIA6
uniprot id: A0A6J3CJR1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transthyretin family.
messages: Homotetramer.
messages: Secreted
messages: Thyroid hormone-binding protein. Probably transports thyroxine from the bloodstream to the brain.

219594:CCNH
gene id: 219594:CCNH
uniprot id: A0A6J3EFC6
names: Function
names: Similarity
names: Subunit
messages: Associates primarily with CDK7 and MAT1 to form the CAK complex. CAK can further associate with the core-TFIIH to form the TFIIH basal transcription factor.
messages: Belongs to the cyclin family. Cyclin C subfamily.
messages: Regulates CDK7, the catalytic subunit of the CDK-activating kinase (CAK) enzymatic complex. CAK activates the cyclin-associated kinases CDK1, CDK2, CDK4 and CDK6 by threonine phosphorylation. CAK complexed to the core-TFIIH basal transcription factor activates RNA polymerase II by serine phosphorylation of the repetitive C-terminal domain (CTD) of its large subunit (POLR2A), allowing its escape from the promoter and elongation of the transcripts. Involved in cell cycle control and in RNA transcription by RNA polymerase II. Its expression and activity are constant throughout the cell cycle.

219594:CDH4
gene id: 219594:CDH4
uniprot id: A0A6J3DVX7
names: Function
names: Subcellular Location Annotation
messages: Cadherins are calcium-dependent cell adhesion proteins.
messages: Cell membrane

219594:TMEM170A
gene id: 219594:TMEM170A
uniprot id: A0A6J3DPY1
uniprot id: A0A6J3DQL7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM170 family.
messages: Membrane

219594:MYH10
gene id: 219594:MYH10
uniprot id: A0A6J3DWI3
uniprot id: A0A6J3DYB9
uniprot id: A0A6J3E0P1
uniprot id: A0A6J3E2K8
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.

219594:AFG3L2
gene id: 219594:AFG3L2
uniprot id: A0A6J3CGB3
uniprot id: A0A6J3CI54
names: Similarity
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the N-terminal section; belongs to the AAA ATPase family.

219594:SLC25A25
gene id: 219594:SLC25A25
uniprot id: A0A6J3DXL0
uniprot id: A0A6J3DZB4
uniprot id: A0A6J3E1R9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane
messages: Mitochondrion inner membrane

219594:LOC116494560
gene id: 219594:LOC116494560
uniprot id: A0A6J3DP10
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0389 family.
messages: Membrane

219594:NAA35
gene id: 219594:NAA35
uniprot id: A0A6J3EEM0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MAK10 family.
messages: Component of the N-terminal acetyltransferase C (NatC) complex, which is composed of NAA35, NAA38 and NAA30.
messages: Cytoplasm

219594:LRP5
gene id: 219594:LRP5
uniprot id: A0A6J3D084
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LDLR family.
messages: Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalosomes.
messages: Homodimer; disulfide-linked. Forms phosphorylated oligomer aggregates on Wnt-signaling.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:TMEM181
gene id: 219594:TMEM181
uniprot id: A0A6J3CMB6
uniprot id: A0A6J3CP55
uniprot id: A0A6J3CTE1
names: Subcellular Location Annotation
messages: Membrane

219594:LOC116485591
gene id: 219594:LOC116485591
uniprot id: A0A6J3CJI4
names: Subcellular Location Annotation
messages: Golgi apparatus membrane
messages: Membrane

219594:DMRTA2
gene id: 219594:DMRTA2
uniprot id: A0A6J3DEL6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DMRT family.
messages: Nucleus

219594:ABLIM2
gene id: 219594:ABLIM2
uniprot id: A0A6J3CTV4
uniprot id: A0A6J3CTV8
uniprot id: A0A6J3CTW3
uniprot id: A0A6J3CW53
uniprot id: A0A6J3CW57
uniprot id: A0A6J3CW61
uniprot id: A0A6J3CWJ4
uniprot id: A0A6J3CWJ7
uniprot id: A0A6J3CWK2
uniprot id: A0A6J3CYX7
uniprot id: A0A6J3CYY2
uniprot id: A0A6J3CZY8
names: Subcellular Location Annotation
messages: Cytoplasm

219594:ANAPC4
gene id: 219594:ANAPC4
uniprot id: A0A6J3CYD4
names: Function
names: Similarity
messages: Belongs to the APC4 family.
messages: Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle.

219594:LOC116502373
gene id: 219594:LOC116502373
uniprot id: A0A6J3EK20
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2A family.
messages: Chromosome
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

219594:CDIP1
gene id: 219594:CDIP1
uniprot id: A0A6J3DTX2
uniprot id: A0A6J3DVP8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDIP1/LITAF family.
messages: Lysosome membrane

219594:SEC13
gene id: 219594:SEC13
uniprot id: A0A6J3DFF8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat SEC13 family.
messages: Lysosome membrane

219594:SKAP1
gene id: 219594:SKAP1
uniprot id: A0A6J3E938
names: Similarity
messages: Belongs to the SKAP family.

219594:STAG1
gene id: 219594:STAG1
uniprot id: A0A6J3DCW8
uniprot id: A0A6J3DIF8
uniprot id: A0A6J3DJ08
uniprot id: A0A6J3DJ14
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SCC3 family.
messages: Chromosome
messages: Component of cohesin complex, a complex required for the cohesion of sister chromatids after DNA replication. The cohesin complex apparently forms a large proteinaceous ring within which sister chromatids can be trapped. At anaphase, the complex is cleaved and dissociates from chromatin, allowing sister chromatids to segregate.
messages: Nucleus
messages: Part of the cohesin complex which is composed of a heterodimer between a SMC1 protein (SMC1A or SMC1B) and SMC3, which are attached via their hinge domain, and RAD21 which link them at their heads, and one STAG protein.
messages: centromere

219594:ST6GAL2
gene id: 219594:ST6GAL2
uniprot id: A0A6J3EQ86
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

219594:ASF1A
gene id: 219594:ASF1A
uniprot id: A0A6J3CT60
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ASF1 family.
messages: Nucleus

219594:TYR
gene id: 219594:TYR
uniprot id: A0A6J3ELG3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tyrosinase family.
messages: Melanosome membrane
messages: Membrane

219594:ADGRL3
gene id: 219594:ADGRL3
uniprot id: A0A6J3CT97
uniprot id: A0A6J3CTA5
uniprot id: A0A6J3CTA9
uniprot id: A0A6J3CTB4
uniprot id: A0A6J3CVL9
uniprot id: A0A6J3CVM4
uniprot id: A0A6J3CW24
uniprot id: A0A6J3CW34
uniprot id: A0A6J3CYD2
uniprot id: A0A6J3CYD8
uniprot id: A0A6J3CYE4
uniprot id: A0A6J3CYE9
uniprot id: A0A6J3CZF7
uniprot id: A0A6J3CZG1
uniprot id: A0A6J3CZG6
uniprot id: A0A6J3CZH1
names: Subcellular Location Annotation
messages: Membrane

219594:LOC116497012
gene id: 219594:LOC116497012
uniprot id: A0A6J3DYE4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ClpA/ClpB family. Torsin subfamily.
messages: Endoplasmic reticulum lumen

219594:PMS1
gene id: 219594:PMS1
uniprot id: A0A6J3D6T9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: Nucleus

219594:PTGES3
gene id: 219594:PTGES3
uniprot id: A0A6J3EAN8
uniprot id: A0A6J3EFR1
names: Similarity
messages: Belongs to the p23/wos2 family.

219594:PARD3
gene id: 219594:PARD3
uniprot id: A0A6J3CJG1
uniprot id: A0A6J3CJG6
uniprot id: A0A6J3CJH0
uniprot id: A0A6J3CJH6
uniprot id: A0A6J3CJI1
uniprot id: A0A6J3CKX0
uniprot id: A0A6J3CKX5
uniprot id: A0A6J3CKY1
uniprot id: A0A6J3CKY7
uniprot id: A0A6J3CM37
uniprot id: A0A6J3CM44
uniprot id: A0A6J3CM53
uniprot id: A0A6J3CP26
uniprot id: A0A6J3CP31
uniprot id: A0A6J3CP37
uniprot id: A0A6J3CP40
uniprot id: A0A6J3CQE5
uniprot id: A0A6J3CQF0
uniprot id: A0A6J3CQF5
uniprot id: A0A6J3CQG0
uniprot id: A0A6J3CQG6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAR3 family.
messages: Cell junction
messages: Endomembrane system

219594:FGD4
gene id: 219594:FGD4
uniprot id: A0A6J3EC63
uniprot id: A0A6J3EIV6
names: Subcellular Location Annotation
messages: cytoskeleton

219594:PIAS3
gene id: 219594:PIAS3
uniprot id: A0A6J3EA44
names: Similarity
messages: Belongs to the PIAS family.

219594:YPEL5
gene id: 219594:YPEL5
uniprot id: A0A6J3CQ55
names: Similarity
messages: Belongs to the yippee family.

219594:LOC116497222
gene id: 219594:LOC116497222
uniprot id: A0A6J3DZF5
uniprot id: A0A6J3E3P5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Spinster (TC 2.A.1.49) family.
messages: Membrane

219594:HIBADH
gene id: 219594:HIBADH
uniprot id: A0A6J3CL54
names: Similarity
messages: Belongs to the HIBADH-related family. 3-hydroxyisobutyrate dehydrogenase subfamily.

219594:PAFAH1B1
gene id: 219594:PAFAH1B1
uniprot id: A0A6J3E022
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the WD repeat LIS1/nudF family.
messages: Can self-associate. Interacts with dynein, dynactin, NDE1 and NDEL1.
messages: Dimerization mediated by the LisH domain may be required to activate dynein.
messages: Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for several dynein- and microtubule-dependent processes such as the maintenance of Golgi integrity, the peripheral transport of microtubule fragments and the coupling of the nucleus and centrosome. May be required for proliferation of neuronal precursors and neuronal migration.
messages: centrosome
messages: cytoskeleton

219594:TFB1M
gene id: 219594:TFB1M
uniprot id: A0A6J3CSC9
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family.

219594:TACR3
gene id: 219594:TACR3
uniprot id: A0A6J3CXC6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

219594:ACADM
gene id: 219594:ACADM
uniprot id: A0A6J3EHX4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acyl-CoA dehydrogenase family.
messages: Mitochondrion matrix

219594:NIPAL4
gene id: 219594:NIPAL4
uniprot id: A0A6J3DQJ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NIPA family.
messages: Membrane

219594:PKP3
gene id: 219594:PKP3
uniprot id: A0A6J3D0E5
names: Similarity
messages: Belongs to the beta-catenin family.

219594:TBX22
gene id: 219594:TBX22
uniprot id: A0A6J3DP30
uniprot id: A0A6J3DT00
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

219594:TMEM86A
gene id: 219594:TMEM86A
uniprot id: A0A6J3CXQ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM86 family.
messages: Membrane

219594:LOC116485370
gene id: 219594:LOC116485370
uniprot id: A0A6J3CGK3
names: Similarity
messages: Belongs to the serpin family.

219594:EIF3B
gene id: 219594:EIF3B
uniprot id: A0A6J3DRW8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-3 subunit B family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is composed of 13 subunits: EIF3A, EIF3B, EIF3C, EIF3D, EIF3E, EIF3F, EIF3G, EIF3H, EIF3I, EIF3J, EIF3K, EIF3L and EIF3M.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome.
messages: Cytoplasm
messages: RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.

219594:LOC116494704
gene id: 219594:LOC116494704
uniprot id: A0A6J3DMD1
uniprot id: A0A6J3DPP4
uniprot id: A0A6J3DRP3
uniprot id: A0A6J3DSH1
uniprot id: A0A6J3DSH4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2A family.
messages: Chromosome
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers.
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.
messages: Variant histone H2A which replaces conventional H2A in a subset of nucleosomes.

219594:NECAP2
gene id: 219594:NECAP2
uniprot id: A0A6J3E2L1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NECAP family.
messages: Involved in endocytosis.
messages: clathrin-coated vesicle membrane

219594:GLRA3
gene id: 219594:GLRA3
uniprot id: A0A6J3CWC2
uniprot id: A0A6J3CWR0
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synapse
messages: Synaptic cell membrane

219594:GRIN3B
gene id: 219594:GRIN3B
uniprot id: A0A6J3E7G5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Receptor for glutamate that functions as a ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system.

219594:CLCN4
gene id: 219594:CLCN4
uniprot id: A0A6J3EQ64
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chloride channel (TC 2.A.49) family.
messages: Membrane

219594:LOC116498231
gene id: 219594:LOC116498231
uniprot id: A0A6J3E415
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TGF-beta family.
messages: Secreted

219594:CSGALNACT1
gene id: 219594:CSGALNACT1
uniprot id: A0A6J3D2H1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chondroitin N-acetylgalactosaminyltransferase family.
messages: Golgi stack membrane
messages: Membrane

219594:LOC116492175
gene id: 219594:LOC116492175
uniprot id: A0A6J3DDL2
uniprot id: A0A6J3DEN1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TOR1AIP family.
messages: Membrane

219594:CENPJ
gene id: 219594:CENPJ
uniprot id: A0A6J3CG87
uniprot id: A0A6J3CI29
names: Similarity
messages: Belongs to the TCP10 family.

219594:LOC116496598
gene id: 219594:LOC116496598
uniprot id: A0A6J3E1D3
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

219594:HMX2
gene id: 219594:HMX2
uniprot id: A0A6J3DDX5
names: Subcellular Location Annotation
messages: Nucleus

219594:LOC116501382
gene id: 219594:LOC116501382
uniprot id: A0A6J3EGD6
uniprot id: A0A6J3ELM1
uniprot id: A0A6J3EN32
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

219594:SPC25
gene id: 219594:SPC25
uniprot id: A0A6J3DAK7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity.
messages: Belongs to the SPC25 family.
messages: Component of the NDC80 complex.
messages: Nucleus
messages: kinetochore

219594:LOC116499634
gene id: 219594:LOC116499634
uniprot id: A0A6J3E9D8
uniprot id: A0A6J3EG64
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 30 family.
messages: Lysosome membrane

219594:TRIM45
gene id: 219594:TRIM45
uniprot id: A0A6J3DEJ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRIM/RBCC family.
messages: Cytoplasm

219594:HNRNPD
gene id: 219594:HNRNPD
uniprot id: A0A6J3D0K7
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

219594:POLR2K
gene id: 219594:POLR2K
uniprot id: A0A6J3CH97
names: Similarity
messages: Belongs to the archaeal Rpo12/eukaryotic RPC10 RNA polymerase subunit family.

219594:LAMP5
gene id: 219594:LAMP5
uniprot id: A0A6J3CWC4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LAMP family.
messages: Endosome membrane
messages: Membrane

219594:MCCC2
gene id: 219594:MCCC2
uniprot id: A0A6J3EFA2
names: Similarity
messages: Belongs to the AccD/PCCB family.

219594:CDK11A
gene id: 219594:CDK11A
uniprot id: A0A6J3E224
uniprot id: A0A6J3E6S0
names: Similarity
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.

219594:UBA3
gene id: 219594:UBA3
uniprot id: A0A6J3DDY4
uniprot id: A0A6J3DGP9
uniprot id: A0A6J3DK26
names: Function
names: Similarity
messages: Belongs to the ubiquitin-activating E1 family. UBA3 subfamily.
messages: Catalytic subunit of the dimeric E1 enzyme, which activates NEDD8.

219594:MOGAT1
gene id: 219594:MOGAT1
uniprot id: A0A6J3DIW2
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the diacylglycerol acyltransferase family.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:DNM3
gene id: 219594:DNM3
uniprot id: A0A6J3DB68
uniprot id: A0A6J3DDS5
uniprot id: A0A6J3DEV6
uniprot id: A0A6J3DH43
names: Similarity
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.

219594:LOC116497691
gene id: 219594:LOC116497691
uniprot id: A0A6J3E1L7
names: Similarity
messages: Belongs to the TAF9 family. CENP-S/MHF1 subfamily.

219594:LOC116485542
gene id: 219594:LOC116485542
uniprot id: A0A6J3CFR1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.
messages: cytoskeleton

219594:PSME3
gene id: 219594:PSME3
uniprot id: A0A6J3E4H8
uniprot id: A0A6J3E8U7
names: Similarity
messages: Belongs to the PA28 family.

219594:ABCG4
gene id: 219594:ABCG4
uniprot id: A0A6J3E2H5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCG family. Eye pigment precursor importer (TC 3.A.1.204) subfamily.
messages: Membrane

219594:NUSAP1
gene id: 219594:NUSAP1
uniprot id: A0A6J3D1F1
uniprot id: A0A6J3D3X4
uniprot id: A0A6J3D4X9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NUSAP family.
messages: Cytoplasm

219594:ACBD5
gene id: 219594:ACBD5
uniprot id: A0A6J3CET2
uniprot id: A0A6J3CGF8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acyl-CoA binding protein which acts as the peroxisome receptor for pexophagy but is dispensable for aggrephagy and nonselective autophagy. Binds medium- and long-chain acyl-CoA esters.
messages: Belongs to the ATG37 family.
messages: Membrane

219594:CRABP1
gene id: 219594:CRABP1
uniprot id: A0A6J3DNX9
names: Similarity
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.

219594:TDRD3
gene id: 219594:TDRD3
uniprot id: A0A6J3D086
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus
messages: Scaffolding protein that specifically recognizes and binds dimethylarginine-containing proteins. Plays a role in the regulation of translation of target mRNAs by binding Arg/Gly-rich motifs (GAR) in dimethylarginine-containing proteins. In nucleus, acts as a coactivator: recognizes and binds asymmetric dimethylation on the core histone tails associated with transcriptional activation (H3R17me2a and H4R3me2a) and recruits proteins at these arginine-methylated loci. In cytoplasm, acts as an antiviral factor that participates in the assembly of stress granules together with G3BP1.

219594:SLC25A22
gene id: 219594:SLC25A22
uniprot id: A0A6J3D174
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

219594:AGTRAP
gene id: 219594:AGTRAP
uniprot id: A0A6J3E171
names: Subcellular Location Annotation
messages: Membrane

219594:GCNT1
gene id: 219594:GCNT1
uniprot id: A0A6J3EG02
names: Subcellular Location Annotation
messages: Golgi apparatus membrane
messages: Membrane

219594:SLC5A12
gene id: 219594:SLC5A12
uniprot id: A0A6J3D5Z8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

219594:GSTZ1
gene id: 219594:GSTZ1
uniprot id: A0A6J3CYV9
uniprot id: A0A6J3D1G3
uniprot id: A0A6J3D4W2
names: Similarity
messages: Belongs to the GST superfamily. Zeta family.

219594:RIN2
gene id: 219594:RIN2
uniprot id: A0A6J3CKZ6
uniprot id: A0A6J3CMJ2
uniprot id: A0A6J3CNM7
uniprot id: A0A6J3CNN2
uniprot id: A0A6J3CQV7
uniprot id: A0A6J3CRY5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. SLC24A subfamily.
messages: Belongs to the RIN (Ras interaction/interference) family.
messages: Membrane

219594:NR2F2
gene id: 219594:NR2F2
uniprot id: A0A6J3DGX3
uniprot id: A0A6J3DMG0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

219594:DMC1
gene id: 219594:DMC1
uniprot id: A0A6J3EA36
names: Similarity
messages: Belongs to the RecA family. DMC1 subfamily.

219594:LOC116490513
gene id: 219594:LOC116490513
uniprot id: A0A6J3D592
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.
messages: cytoskeleton

219594:TYRO3
gene id: 219594:TYRO3
uniprot id: A0A6J3D442
uniprot id: A0A6J3D534
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family.
messages: Membrane

219594:TOPAZ1
gene id: 219594:TOPAZ1
uniprot id: A0A6J3CGM5
names: Function
messages: Important for normal spermatogenesis and male fertility. Specifically required for progression to the post-meiotic stages of spermatocyte development. Seems to be necessary for normal expression levels of a number of testis-expressed gene transcripts, although its role in this process is unclear.

219594:MST1R
gene id: 219594:MST1R
uniprot id: A0A6J3DKW5
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

219594:SCNN1A
gene id: 219594:SCNN1A
uniprot id: A0A6J3EN76
names: Subcellular Location Annotation
messages: Membrane

219594:STRN
gene id: 219594:STRN
uniprot id: A0A6J3CMH4
uniprot id: A0A6J3CQ51
uniprot id: A0A6J3CSF8
uniprot id: A0A6J3CTJ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat striatin family.
messages: Membrane

219594:LOC116502121
gene id: 219594:LOC116502121
uniprot id: A0A6J3EPE0
names: Similarity
messages: Belongs to the cystatin family.

219594:GABRA1
gene id: 219594:GABRA1
uniprot id: A0A6J3DNT0
uniprot id: A0A6J3DU09
uniprot id: A0A6J3DUV3
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family. Gamma-aminobutyric acid receptor (TC 1.A.9.5) subfamily. GABRA1 sub-subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

219594:CCDC93
gene id: 219594:CCDC93
uniprot id: A0A6J3D6S0
names: Similarity
messages: Belongs to the CCDC93 family.

219594:ND1
gene id: 219594:ND1
uniprot id: A0A068LAT2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 1 family.
messages: Membrane
messages: Mitochondrion inner membrane

219594:PIGL
gene id: 219594:PIGL
uniprot id: A0A6J3E5D4
names: Function
names: Similarity
messages: Belongs to the PIGL family.
messages: Involved in the second step of GPI biosynthesis. De-N-acetylation of N-acetylglucosaminyl-phosphatidylinositol.

219594:ALG9
gene id: 219594:ALG9
uniprot id: A0A6J3E3Y4
uniprot id: A0A6J3E6U0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 22 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

219594:LOC116498576
gene id: 219594:LOC116498576
uniprot id: A0A6J3E573
names: Similarity
names: Subunit
messages: Belongs to the avian keratin family.
messages: The avian keratins (F-ker, S-ker, C-ker and B-ker) are a complex mixture of very similar polypeptides.

219594:CUL1
gene id: 219594:CUL1
uniprot id: A0A6J3CJ92
names: Similarity
messages: Belongs to the cullin family.

219594:ADAM8
gene id: 219594:ADAM8
uniprot id: A0A6J3D9T1
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:LOC116493600
gene id: 219594:LOC116493600
uniprot id: A0A6J3DLS5
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZP domain family. ZPC subfamily.
messages: Cell membrane
messages: Component of the zona pellucida, an extracellular matrix surrounding oocytes which mediates sperm binding, induction of the acrosome reaction and prevents post-fertilization polyspermy. The zona pellucida is composed of 3 to 4 glycoproteins, ZP1, ZP2, ZP3, and ZP4. ZP3 is essential for sperm binding and zona matrix formation.
messages: Proteolytically cleaved before the transmembrane segment to yield the secreted ectodomain incorporated in the zona pellucida.
messages: The ZP domain is involved in the polymerization of the ZP proteins to form the zona pellucida.
messages: Zona pellucida

219594:SGCZ
gene id: 219594:SGCZ
uniprot id: A0A6J3CSE5
uniprot id: A0A6J3CUQ0
uniprot id: A0A6J3CV60
uniprot id: A0A6J3CXG6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sarcoglycan beta/delta/gamma/zeta family.
messages: cytoskeleton
messages: sarcolemma

219594:CTNS
gene id: 219594:CTNS
uniprot id: A0A6J3E3U4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cystinosin family.
messages: Membrane

219594:UBN2
gene id: 219594:UBN2
uniprot id: A0A6J3DAK6
names: Similarity
messages: Belongs to the ubinuclein family.

219594:GPR20
gene id: 219594:GPR20
uniprot id: A0A6J3CNY3
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

219594:MRPS26
gene id: 219594:MRPS26
uniprot id: A0A6J3CZ65
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mS26 family.
messages: Mitochondrion

219594:UIMC1
gene id: 219594:UIMC1
uniprot id: A0A6J3DNS4
uniprot id: A0A6J3DR34
uniprot id: A0A6J3DU04
uniprot id: A0A6J3DUU7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RAP80 family.
messages: Nucleus

219594:LOC116487832
gene id: 219594:LOC116487832
uniprot id: A0A6J3CUE5
names: Caution
names: Similarity
messages: Belongs to the CRISP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:XYLT1
gene id: 219594:XYLT1
uniprot id: A0A6J3DPD8
uniprot id: A0A6J3DVH5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycosyltransferase 14 family. XylT subfamily.
messages: Golgi apparatus membrane
messages: Membrane
messages: Monomer.

219594:C9H3orf70
gene id: 219594:C9H3orf70
uniprot id: A0A6J3DFC4
names: Similarity
messages: Belongs to the UPF0524 family.

219594:TOM1L1
gene id: 219594:TOM1L1
uniprot id: A0A6J3DXZ0
names: Similarity
messages: Belongs to the TOM1 family.

219594:SHANK3
gene id: 219594:SHANK3
uniprot id: A0A6J3DSZ6
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Postsynaptic density

219594:RNF8
gene id: 219594:RNF8
uniprot id: A0A6J3CQZ7
names: Similarity
messages: Belongs to the CHFR family.
messages: Belongs to the RNF8 family.

219594:MFSD14A
gene id: 219594:MFSD14A
uniprot id: A0A6J3DEX2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily.
messages: Membrane

219594:NRDE2
gene id: 219594:NRDE2
uniprot id: A0A6J3D3T8
uniprot id: A0A6J3D6D9
names: Similarity
messages: Belongs to the NRDE2 family.

219594:DYRK2
gene id: 219594:DYRK2
uniprot id: A0A6J3DB73
uniprot id: A0A6J3DDT9
names: Similarity
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MNB/DYRK subfamily.

219594:LOC116499339
gene id: 219594:LOC116499339
uniprot id: A0A6J3ECY4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TGF-beta family.
messages: Secreted

219594:CDS2
gene id: 219594:CDS2
uniprot id: A0A6J3E9T1
uniprot id: A0A6J3ECY9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Catalyzes the conversion of phosphatidic acid (PA) to CDP-diacylglycerol (CDP-DAG), an essential intermediate in the synthesis of phosphatidylglycerol, cardiolipin and phosphatidylinositol.
messages: Membrane

219594:LOC116494735
gene id: 219594:LOC116494735
uniprot id: A0A6J3DPV9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SCO1/2 family.
messages: Mitochondrion inner membrane

219594:RELT
gene id: 219594:RELT
uniprot id: A0A6J3EKW9
uniprot id: A0A6J3ERC6
names: Similarity
messages: Belongs to the RELT family.

219594:LSM1
gene id: 219594:LSM1
uniprot id: A0A6J3EFN2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the snRNP Sm proteins family.
messages: Cytoplasm
messages: LSm subunits form a heteromer with a donut shape.
messages: P-body
messages: Probably involved with other LSm subunits in the general process of degradation of mRNAs.

219594:SYNJ2
gene id: 219594:SYNJ2
uniprot id: A0A6J3CP38
uniprot id: A0A6J3CRC3
uniprot id: A0A6J3CSD2
names: Similarity
messages: Belongs to the synaptojanin family.
messages: In the central section; belongs to the inositol 1,4,5-trisphosphate 5-phosphatase family.

219594:MAP2K5
gene id: 219594:MAP2K5
uniprot id: A0A6J3DGT5
uniprot id: A0A6J3DMB3
names: Similarity
messages: Belongs to the protein kinase superfamily.

219594:SERPINH1
gene id: 219594:SERPINH1
uniprot id: A0A6J3DFJ6
names: Function
names: Similarity
messages: Belongs to the serpin family.
messages: Binds specifically to collagen. Could be involved as a chaperone in the biosynthetic pathway of collagen.

219594:SEC11A
gene id: 219594:SEC11A
uniprot id: A0A6J3DMD0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S26B family.
messages: Component of the signal peptidase complex.
messages: Endoplasmic reticulum membrane
messages: Membrane

219594:TRUB2
gene id: 219594:TRUB2
uniprot id: A0A6J3E0A5
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family.

219594:LOC116489991
gene id: 219594:LOC116489991
uniprot id: A0A6J3D594
names: Similarity
messages: Belongs to the protease inhibitor I39 (alpha-2-macroglobulin) family.

219594:NDUFAB1
gene id: 219594:NDUFAB1
uniprot id: A0A6J3DV27
names: Function
names: Similarity
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.

219594:VAX2
gene id: 219594:VAX2
uniprot id: A0A6J3CXF7
names: Subcellular Location Annotation
messages: Nucleus

219594:SHOX2
gene id: 219594:SHOX2
uniprot id: A0A6J3DC11
names: Subcellular Location Annotation
messages: Nucleus

219594:COQ3
gene id: 219594:COQ3
uniprot id: A0A6J3CW96
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. UbiG/COQ3 family.
messages: Component of a multi-subunit COQ enzyme complex, composed of at least COQ3, COQ4, COQ5, COQ6, COQ7 and COQ9.
messages: Mitochondrion inner membrane
messages: O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway.

219594:RPS19BP1
gene id: 219594:RPS19BP1
uniprot id: A0A6J3EQB6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AROS family.
messages: nucleolus

219594:NEU3
gene id: 219594:NEU3
uniprot id: A0A6J3EHN8
names: Similarity
messages: Belongs to the glycosyl hydrolase 33 family.

219594:MSH3
gene id: 219594:MSH3
uniprot id: A0A6J3EJB3
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.
messages: Component of the post-replicative DNA mismatch repair system (MMR).

219594:PFKP
gene id: 219594:PFKP
uniprot id: A0A6J3CGW4
uniprot id: A0A6J3CJL0
uniprot id: A0A6J3CLE5
uniprot id: A0A6J3CN18
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by ADP, AMP, or fructose 2,6-bisphosphate, and allosterically inhibited by ATP or citrate.
messages: Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade "E" sub-subfamily.
messages: Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homo- and heterotetramers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:LOC116502386
gene id: 219594:LOC116502386
uniprot id: A0A6J3ELK4
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phospholipase A2 family.
messages: Binds 1 Ca(2+) ion per subunit.
messages: Secreted

219594:GRK4
gene id: 219594:GRK4
uniprot id: A0A6J3CVL3
uniprot id: A0A6J3CW18
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily.

219594:HTR2A
gene id: 219594:HTR2A
uniprot id: A0A6J3E6P2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Cytoplasmic vesicle
messages: G-protein coupled receptor for 5-hydroxytryptamine (serotonin).
messages: Membrane
messages: Presynapse
messages: Synapse
messages: Vesicle
messages: axon
messages: caveola
messages: dendrite

219594:DDX47
gene id: 219594:DDX47
uniprot id: A0A6J3EQ42
names: Similarity
messages: Belongs to the DEAD box helicase family. DDX47/RRP3 subfamily.

219594:TEC
gene id: 219594:TEC
uniprot id: A0A6J3D2I7
names: Similarity
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.

219594:KIF16B
gene id: 219594:KIF16B
uniprot id: A0A6J3CLK8
uniprot id: A0A6J3CN89
uniprot id: A0A6J3CP83
uniprot id: A0A6J3CRI2
uniprot id: A0A6J3CSI2
uniprot id: A0A6J3CSI7
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

219594:GBE1
gene id: 219594:GBE1
uniprot id: A0A6J3DBW5
uniprot id: A0A6J3DDZ2
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.

219594:LOC116491083
gene id: 219594:LOC116491083
uniprot id: A0A6J3D832
uniprot id: A0A6J3DAS2
names: Subcellular Location Annotation
messages: Endoplasmic reticulum
messages: Mitochondrion

219594:LPAR1
gene id: 219594:LPAR1
uniprot id: A0A6J3ED10
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Cell surface
messages: Endosome
messages: Membrane

219594:HOXC10
gene id: 219594:HOXC10
uniprot id: A0A6J3EBZ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Abd-B homeobox family.
messages: Nucleus

219594:HK2
gene id: 219594:HK2
uniprot id: A0A6J3EFD9
names: Similarity
messages: Belongs to the hexokinase family.

219594:SULT6B1
gene id: 219594:SULT6B1
uniprot id: A0A6J3CWD7
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

219594:KIF27
gene id: 219594:KIF27
uniprot id: A0A6J3EF97
uniprot id: A0A6J3EIP2
uniprot id: A0A6J3EJ41
uniprot id: A0A6J3EKL9
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

219594:DDB2
gene id: 219594:DDB2
uniprot id: A0A6J3D520
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat DDB2/WDR76 family.
messages: Nucleus

219594:UBALD2
gene id: 219594:UBALD2
uniprot id: A0A6J3E169
names: Similarity
messages: Belongs to the UBALD family.

219594:ABRAXAS2
gene id: 219594:ABRAXAS2
uniprot id: A0A6J3DDE3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAM175 family. Abro1 subfamily.
messages: Nucleus
messages: spindle pole

219594:LOC116495457
gene id: 219594:LOC116495457
uniprot id: A0A6J3DWX3
names: Similarity
messages: Belongs to the globin family.

219594:XDH
gene id: 219594:XDH
uniprot id: A0A6J3CPW5
uniprot id: A0A6J3CS67
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the xanthine dehydrogenase family.
messages: Binds 1 Mo-molybdopterin (Mo-MPT) cofactor per subunit.
messages: Binds 2 [2Fe-2S] clusters.
messages: Peroxisome

219594:CHST8
gene id: 219594:CHST8
uniprot id: A0A6J3DIQ5
uniprot id: A0A6J3DL88
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 2 family.
messages: Golgi apparatus membrane
messages: Membrane

219594:DMAP1
gene id: 219594:DMAP1
uniprot id: A0A6J3DH25
names: Subcellular Location Annotation
messages: Nucleus

219594:PEAR1
gene id: 219594:PEAR1
uniprot id: A0A6J3EAH8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:PIGM
gene id: 219594:PIGM
uniprot id: A0A6J3CRS8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PIGM family.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mannosyltransferase involved in glycosylphosphatidylinositol-anchor biosynthesis. Transfers the first alpha-1,4-mannose to GlcN-acyl-PI during GPI precursor assembly.
messages: Membrane

219594:LSM7
gene id: 219594:LSM7
uniprot id: A0A6J3E8M6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the snRNP Sm proteins family.
messages: Nucleus

219594:LOC116499802
gene id: 219594:LOC116499802
uniprot id: A0A6J3EGU2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

219594:NUDCD1
gene id: 219594:NUDCD1
uniprot id: A0A6J3CFW3
uniprot id: A0A6J3CGV1
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

219594:DCN
gene id: 219594:DCN
uniprot id: A0A6J3CND0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class I subfamily.
messages: Binds to type I and type II collagen, fibronectin and TGF-beta. Forms a ternary complex with MFAP2 and ELN.
messages: May affect the rate of fibrils formation.
messages: extracellular matrix

219594:MIOX
gene id: 219594:MIOX
uniprot id: A0A6J3DQ32
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the myo-inositol oxygenase family.
messages: Binds 2 iron ions per subunit.
messages: Cytoplasm

219594:LOC116485735
gene id: 219594:LOC116485735
uniprot id: A0A6J3CDV4
uniprot id: A0A6J3CFH3
uniprot id: A0A6J3CID7
uniprot id: A0A6J3CK25
names: Subcellular Location Annotation
messages: Cytoplasm

219594:SNX4
gene id: 219594:SNX4
uniprot id: A0A6J3D911
names: Similarity
messages: Belongs to the sorting nexin family.

219594:ABCB11
gene id: 219594:ABCB11
uniprot id: A0A6J3D3S6
uniprot id: A0A6J3D6V7
uniprot id: A0A6J3D9P5
names: Subcellular Location Annotation
messages: Membrane

219594:TIMM21
gene id: 219594:TIMM21
uniprot id: A0A6J3CJ18
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TIM21 family.
messages: Component of the TIM23 complex.
messages: Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane.
messages: Membrane
messages: Mitochondrion inner membrane
messages: Mitochondrion membrane

219594:LOC116502359
gene id: 219594:LOC116502359
uniprot id: A0A6J3ELI0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2B family.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

219594:SMG6
gene id: 219594:SMG6
uniprot id: A0A6J3DZY3
uniprot id: A0A6J3E4Z9
names: Domain
names: Function
names: Subcellular Location Annotation
messages: Component of the telomerase ribonucleoprotein (RNP) complex that is essential for the replication of chromosome termini.
messages: Plays a role in nonsense-mediated mRNA decay.
messages: The PINc domain confers endonuclease activity and is expected to bind the catalytic metal ion.
messages: cytosol
messages: nucleolus
messages: telomere

219594:CTSK
gene id: 219594:CTSK
uniprot id: A0A6J3E9C7
uniprot id: A0A6J3EEG8
names: Similarity
messages: Belongs to the peptidase C1 family.

219594:CLASP1
gene id: 219594:CLASP1
uniprot id: A0A6J3D508
uniprot id: A0A6J3D513
uniprot id: A0A6J3D7Q0
uniprot id: A0A6J3D7Q5
uniprot id: A0A6J3D7R0
uniprot id: A0A6J3D874
uniprot id: A0A6J3D879
uniprot id: A0A6J3DAE5
uniprot id: A0A6J3DAF0
uniprot id: A0A6J3DAX4
uniprot id: A0A6J3DAX9
names: Subcellular Location Annotation
messages: kinetochore

219594:BRAF
gene id: 219594:BRAF
uniprot id: A0A6J3DCE7
uniprot id: A0A6J3DF48
names: Similarity
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. RAF subfamily.

219594:FAM120A
gene id: 219594:FAM120A
uniprot id: A0A6J3DFP8
uniprot id: A0A6J3DJN5
names: Similarity
messages: Belongs to the constitutive coactivator of PPAR-gamma family.

219594:PELO
gene id: 219594:PELO
uniprot id: A0A6J3EJA6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic release factor 1 family. Pelota subfamily.
messages: Component of the Pelota-HBS1L complex, a complex that recognizes stalled ribosomes and triggers the No-Go Decay (NGD) pathway. In the Pelota-HBS1L complex, pelo recognizes ribosomes stalled at the 3' end of an mRNA and engages stalled ribosomes by destabilizing mRNA in the mRNA channel.
messages: Cytoplasm

219594:LOC116496235
gene id: 219594:LOC116496235
uniprot id: A0A6J3DWG3
uniprot id: A0A6J3DZI9
uniprot id: A0A6J3E0J6
names: Similarity
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.

219594:FAM83A
gene id: 219594:FAM83A
uniprot id: A0A6J3CLF1
names: Similarity
messages: Belongs to the FAM83 family.

219594:MBD4
gene id: 219594:MBD4
uniprot id: A0A6J3DKV5
names: Subcellular Location Annotation
messages: Nucleus

219594:LDLRAD3
gene id: 219594:LDLRAD3
uniprot id: A0A6J3D0G3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:NKAIN3
gene id: 219594:NKAIN3
uniprot id: A0A6J3CDQ6
uniprot id: A0A6J3CGC5
uniprot id: A0A6J3CI86
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NKAIN family.
messages: Cell membrane
messages: Membrane

219594:LOC116501326
gene id: 219594:LOC116501326
uniprot id: A0A6J3EMW2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

219594:HTR1A
gene id: 219594:HTR1A
uniprot id: A0A6J3ELY9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

219594:FGF7
gene id: 219594:FGF7
uniprot id: A0A6J3DI05
names: Similarity
messages: Belongs to the heparin-binding growth factors family.

219594:REXO4
gene id: 219594:REXO4
uniprot id: A0A6J3E246
names: Similarity
messages: Belongs to the REXO4 family.

219594:IGF1R
gene id: 219594:IGF1R
uniprot id: A0A6J3DJS0
uniprot id: A0A6J3DN84
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. Insulin receptor subfamily.
messages: Membrane

219594:NMUR2
gene id: 219594:NMUR2
uniprot id: A0A6J3DSX8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for the neuromedin-U and neuromedin-S neuropeptides.

219594:HOXC6
gene id: 219594:HOXC6
uniprot id: A0A6J3EH96
names: Subcellular Location Annotation
messages: Nucleus

219594:BANP
gene id: 219594:BANP
uniprot id: A0A6J3DMI0
uniprot id: A0A6J3DP91
names: Similarity
messages: Belongs to the BANP/SMAR1 family.

219594:CAVIN2
gene id: 219594:CAVIN2
uniprot id: A0A6J3D9X1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CAVIN family.
messages: caveola

219594:PSAT1
gene id: 219594:PSAT1
uniprot id: A0A6J3EL61
names: Function
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
messages: Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.

219594:CTNNA3
gene id: 219594:CTNNA3
uniprot id: A0A6J3D7S3
uniprot id: A0A6J3DAF9
uniprot id: A0A6J3DDC5
uniprot id: A0A6J3DDC9
uniprot id: A0A6J3DDQ5
names: Similarity
messages: Belongs to the vinculin/alpha-catenin family.

219594:HOXB2
gene id: 219594:HOXB2
uniprot id: A0A6J3E501
names: Subcellular Location Annotation
messages: Nucleus

219594:TVP23A
gene id: 219594:TVP23A
uniprot id: A0A6J3DRY5
uniprot id: A0A6J3DTZ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TVP23 family.
messages: Membrane

219594:NPY
gene id: 219594:NPY
uniprot id: A0A6J3CII4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NPY family.
messages: Secreted

219594:MYO9B
gene id: 219594:MYO9B
uniprot id: A0A6J3E6X8
uniprot id: A0A6J3E8F2
uniprot id: A0A6J3EBG2
uniprot id: A0A6J3EBZ2
uniprot id: A0A6J3EDM3
uniprot id: A0A6J3EDM8
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.

219594:SIX3
gene id: 219594:SIX3
uniprot id: A0A6J3CX00
names: Subcellular Location Annotation
messages: Nucleus

219594:USP10
gene id: 219594:USP10
uniprot id: A0A6J3DPB4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C19 family. USP10 subfamily.
messages: Cytoplasm

219594:PLA2G12A
gene id: 219594:PLA2G12A
uniprot id: A0A6J3CUX2
names: Subcellular Location Annotation
messages: Secreted

219594:WDR48
gene id: 219594:WDR48
uniprot id: A0A6J3CFM7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat WDR48 family.
messages: Late endosome

219594:LOC116498580
gene id: 219594:LOC116498580
uniprot id: A0A6J3E573
names: Similarity
names: Subunit
messages: Belongs to the avian keratin family.
messages: The avian keratins (F-ker, S-ker, C-ker and B-ker) are a complex mixture of very similar polypeptides.

219594:PPM1L
gene id: 219594:PPM1L
uniprot id: A0A6J3DBJ3
names: Similarity
messages: Belongs to the PP2C family.

219594:DEUP1
gene id: 219594:DEUP1
uniprot id: A0A6J3EPZ1
names: Similarity
messages: Belongs to the CEP63 family.

219594:PARD6A
gene id: 219594:PARD6A
uniprot id: A0A6J3DPW1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAR6 family.
messages: Cytoplasm
messages: tight junction

219594:ADI1
gene id: 219594:ADI1
uniprot id: A0A6J3CQP7
uniprot id: A0A6J3CSZ2
uniprot id: A0A6J3CWV2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acireductone dioxygenase (ARD) family.
messages: Binds either 1 Fe or Ni cation per monomer. Iron-binding promotes an acireductone dioxygenase reaction producing 2-keto-4-methylthiobutyrate, while nickel-binding promotes an acireductone dioxygenase reaction producing 3-(methylsulfanyl)propanoate.
messages: Catalyzes 2 different reactions between oxygen and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4-methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer.
messages: Nucleus

219594:MAPK4
gene id: 219594:MAPK4
uniprot id: A0A6J3EMG6
names: Similarity
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MAP kinase subfamily.

219594:TRPV4
gene id: 219594:TRPV4
uniprot id: A0A6J3DWI5
names: Subcellular Location Annotation
messages: Membrane

219594:LOC116495333
gene id: 219594:LOC116495333
uniprot id: A0A6J3DWE8
names: Similarity
messages: Belongs to the cytochrome P450 family.

219594:RASSF1
gene id: 219594:RASSF1
uniprot id: A0A6J3DHI4
names: Subcellular Location Annotation
messages: cytoskeleton

219594:KCNT2
gene id: 219594:KCNT2
uniprot id: A0A6J3D8J5
uniprot id: A0A6J3DBC3
uniprot id: A0A6J3DC63
uniprot id: A0A6J3DEJ6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

219594:MID1IP1
gene id: 219594:MID1IP1
uniprot id: A0A6J3EJA7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPOT14 family.
messages: Cytoplasm
messages: Nucleus

219594:ARL4C
gene id: 219594:ARL4C
uniprot id: A0A6J3D4Q6
names: Similarity
messages: Belongs to the small GTPase superfamily. Arf family.

219594:SESN1
gene id: 219594:SESN1
uniprot id: A0A6J3CLL5
uniprot id: A0A6J3CN99
uniprot id: A0A6J3CP92
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sestrin family.
messages: Cytoplasm

219594:ALDH8A1
gene id: 219594:ALDH8A1
uniprot id: A0A6J3CT37
uniprot id: A0A6J3CVD6
uniprot id: A0A6J3CWI7
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

219594:LOC116498291
gene id: 219594:LOC116498291
uniprot id: A0A6J3E5K8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

219594:TMEM129
gene id: 219594:TMEM129
uniprot id: A0A6J3CX52
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM129 family.
messages: Membrane

219594:MIXL1
gene id: 219594:MIXL1
uniprot id: A0A6J3CRV6
names: Subcellular Location Annotation
messages: Nucleus

219594:ABCG1
gene id: 219594:ABCG1
uniprot id: A0A6J3EPV1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCG family. Eye pigment precursor importer (TC 3.A.1.204) subfamily.
messages: Membrane

219594:TBK1
gene id: 219594:TBK1
uniprot id: A0A6J3EJD9
names: Subcellular Location Annotation
messages: Cytoplasm

219594:MYOC
gene id: 219594:MYOC
uniprot id: A0A6J3DGE2
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:CEMIP
gene id: 219594:CEMIP
uniprot id: A0A6J3DG64
uniprot id: A0A6J3DLR0
names: Similarity
messages: Belongs to the CEMIP family.

219594:LAMA4
gene id: 219594:LAMA4
uniprot id: A0A6J3CSS1
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: basement membrane

219594:RPL7A
gene id: 219594:RPL7A
uniprot id: A0A6J3DYF2
names: Function
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL8 family.
messages: Component of the ribosome.

219594:MYO1D
gene id: 219594:MYO1D
uniprot id: A0A6J3EA21
uniprot id: A0A6J3EBH1
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.

219594:TPD52L2
gene id: 219594:TPD52L2
uniprot id: A0A6J3DRJ2
uniprot id: A0A6J3DTQ3
uniprot id: A0A6J3DTQ8
uniprot id: A0A6J3DVW3
uniprot id: A0A6J3DXQ2
names: Similarity
messages: Belongs to the TPD52 family.

219594:LOC116496924
gene id: 219594:LOC116496924
uniprot id: A0A6J3E254
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the POU transcription factor family.
messages: Nucleus

219594:GUCY2F
gene id: 219594:GUCY2F
uniprot id: A0A6J3EIS3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
messages: Membrane

219594:MARCKS
gene id: 219594:MARCKS
uniprot id: A0A6J3CW43
names: Similarity
messages: Belongs to the MARCKS family.

219594:LOC116501948
gene id: 219594:LOC116501948
uniprot id: A0A6J3EQK2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H4 family.
messages: Chromosome
messages: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

219594:LOC116500115
gene id: 219594:LOC116500115
uniprot id: A0A6J3EB56
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:ECHDC2
gene id: 219594:ECHDC2
uniprot id: A0A6J3DEQ8
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

219594:GNG2
gene id: 219594:GNG2
uniprot id: A0A6J3D6P3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G protein gamma family.
messages: Cell membrane
messages: G proteins are composed of 3 units; alpha, beta and gamma.
messages: Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.

219594:TRAF3
gene id: 219594:TRAF3
uniprot id: A0A6J3CY46
uniprot id: A0A6J3D451
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TNF receptor-associated factor family.
messages: Cytoplasm

219594:LOC116490499
gene id: 219594:LOC116490499
uniprot id: A0A6J3D2N4
names: Similarity
names: Subunit
messages: Belongs to the avian keratin family.
messages: The avian keratins (F-ker, S-ker, C-ker and B-ker) are a complex mixture of very similar polypeptides.

219594:ARSJ
gene id: 219594:ARSJ
uniprot id: A0A6J3CUM4
names: Similarity
messages: Belongs to the sulfatase family.

219594:MRPS7
gene id: 219594:MRPS7
uniprot id: A0A6J3DVL5
names: Similarity
messages: Belongs to the universal ribosomal protein uS7 family.

219594:PCBP4
gene id: 219594:PCBP4
uniprot id: A0A6J3DF81
names: Subcellular Location Annotation
messages: Cytoplasm

219594:TXLNB
gene id: 219594:TXLNB
uniprot id: A0A6J3CSN2
names: Similarity
messages: Belongs to the taxilin family.

219594:SRP54
gene id: 219594:SRP54
uniprot id: A0A6J3D1I6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Component of the signal recognition particle (SRP) complex, a ribonucleoprotein complex that mediates the cotranslational targeting of secretory and membrane proteins to the endoplasmic reticulum (ER).
messages: Cytoplasm
messages: Endoplasmic reticulum
messages: Nucleus speckle
messages: The M domain binds the 7SL RNA in presence of SRP19 and binds the signal sequence of presecretory proteins.
messages: The NG domain, also named G domain, is a special guanosine triphosphatase (GTPase) domain, which binds GTP and forms a guanosine 5'-triphosphate (GTP)-dependent complex with a homologous NG domain in the SRP receptor subunit SRPRA. The two NG domains undergo cooperative rearrangements upon their assembly, which culminate in the reciprocal activation of the GTPase activity of one another. SRP receptor compaction upon binding with cargo-loaded SRP and GTPase rearrangement drive SRP-mediated cotranslational protein translocation into the ER.

219594:SH3GLB1
gene id: 219594:SH3GLB1
uniprot id: A0A6J3DCS1
uniprot id: A0A6J3DDS7
uniprot id: A0A6J3DFV9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endophilin family.
messages: Cytoplasm
messages: Golgi apparatus membrane
messages: Mitochondrion outer membrane

219594:TMCC2
gene id: 219594:TMCC2
uniprot id: A0A6J3E6K1
uniprot id: A0A6J3EBM6
names: Similarity
messages: Belongs to the TEX28 family.

219594:DUSP4
gene id: 219594:DUSP4
uniprot id: A0A6J3CV37
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.
messages: Nucleus

219594:ENTPD7
gene id: 219594:ENTPD7
uniprot id: A0A6J3DCN4
names: Similarity
messages: Belongs to the GDA1/CD39 NTPase family.

219594:ANXA13
gene id: 219594:ANXA13
uniprot id: A0A6J3CI95
names: Domain
names: Similarity
messages: A pair of annexin repeats may form one binding site for calcium and phospholipid.
messages: Belongs to the annexin family.

219594:KCNK12
gene id: 219594:KCNK12
uniprot id: A0A6J3CS95
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
messages: Membrane

219594:GTF2A1
gene id: 219594:GTF2A1
uniprot id: A0A6J3D277
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TFIIA subunit 1 family.
messages: Nucleus

219594:LOC116492525
gene id: 219594:LOC116492525
uniprot id: A0A6J3DI17
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:DNPEP
gene id: 219594:DNPEP
uniprot id: A0A6J3DB34
names: Similarity
names: Subunit
messages: Belongs to the peptidase M18 family.
messages: Tetrahedron-shaped homododecamer built from six homodimers.

219594:LOC116488940
gene id: 219594:LOC116488940
uniprot id: A0A6J3CXF1
names: Subcellular Location Annotation
messages: Nucleus

219594:VCAN
gene id: 219594:VCAN
uniprot id: A0A6J3EH50
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

219594:TENM1
gene id: 219594:TENM1
uniprot id: A0A6J3DL74
uniprot id: A0A6J3DNM3
uniprot id: A0A6J3DNM8
uniprot id: A0A6J3DQI4
uniprot id: A0A6J3DRJ5
uniprot id: A0A6J3DSJ0
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tenascin family. Teneurin subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

219594:KDM1B
gene id: 219594:KDM1B
uniprot id: A0A6J3CFP6
names: Similarity
messages: Belongs to the flavin monoamine oxidase family.

219594:PRPH
gene id: 219594:PRPH
uniprot id: A0A6J3EAV0
uniprot id: A0A6J3EFK7
names: Similarity
messages: Belongs to the intermediate filament family.

219594:OGN
gene id: 219594:OGN
uniprot id: A0A6J3DK79
names: Similarity
messages: Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class III subfamily.

219594:PEPD
gene id: 219594:PEPD
uniprot id: A0A6J3DNH9
names: Similarity
messages: Belongs to the peptidase M24B family.

219594:CENPO
gene id: 219594:CENPO
uniprot id: A0A6J3CRR2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CENP-O/MCM21 family.
messages: Nucleus

219594:LOC116485802
gene id: 219594:LOC116485802
uniprot id: A0A6J3CFY9
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

219594:CERS4
gene id: 219594:CERS4
uniprot id: A0A6J3EDU1
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Nucleus

219594:TMC3
gene id: 219594:TMC3
uniprot id: A0A6J3DJ60
uniprot id: A0A6J3DM17
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMC family.
messages: Membrane

219594:RAD50
gene id: 219594:RAD50
uniprot id: A0A6J3DSU1
names: Similarity
messages: Belongs to the SMC family. RAD50 subfamily.

219594:ZDHHC9
gene id: 219594:ZDHHC9
uniprot id: A0A6J3DS51
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

219594:PDZK1IP1
gene id: 219594:PDZK1IP1
uniprot id: A0A6J3DE80
names: Subcellular Location Annotation
messages: Membrane

219594:CDO1
gene id: 219594:CDO1
uniprot id: A0A6J3EFC1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the cysteine dioxygenase family.
messages: Binds 1 Fe cation per subunit.
messages: Catalyzes the oxidation of cysteine to cysteine sulfinic acid with addition of molecular dioxygen.

219594:LOC116498314
gene id: 219594:LOC116498314
uniprot id: A0A6J3E484
names: Similarity
names: Subunit
messages: Belongs to the avian keratin family.
messages: The avian keratins (F-ker, S-ker, C-ker and B-ker) are a complex mixture of very similar polypeptides.

219594:ATP10D
gene id: 219594:ATP10D
uniprot id: A0A6J3CW84
uniprot id: A0A6J3CWM5
uniprot id: A0A6J3CZ11
uniprot id: A0A6J3D043
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.
messages: Membrane

219594:TRPC4
gene id: 219594:TRPC4
uniprot id: A0A6J3ELL3
names: Subcellular Location Annotation
messages: Membrane

219594:YPEL4
gene id: 219594:YPEL4
uniprot id: A0A6J3CZG3
names: Similarity
messages: Belongs to the yippee family.

219594:CENPX
gene id: 219594:CENPX
uniprot id: A0A6J3E0A3
names: Similarity
messages: Belongs to the CENP-X/MHF2 family.

219594:NUP98
gene id: 219594:NUP98
uniprot id: A0A6J3DZ44
uniprot id: A0A6J3E1H4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleoporin GLFG family.
messages: Nucleus membrane
messages: nuclear pore complex

219594:NFS1
gene id: 219594:NFS1
uniprot id: A0A6J3DS58
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.

219594:GJB7
gene id: 219594:GJB7
uniprot id: A0A6J3CVM6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

219594:PUSL1
gene id: 219594:PUSL1
uniprot id: A0A6J3E5R5
names: Similarity
messages: Belongs to the tRNA pseudouridine synthase TruA family.

219594:CLP1
gene id: 219594:CLP1
uniprot id: A0A6J3D522
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Clp1 family. Clp1 subfamily.
messages: Component of the tRNA splicing endonuclease complex. Component of pre-mRNA cleavage complex II (CF-II).
messages: Nucleus
messages: Polynucleotide kinase that can phosphorylate the 5'-hydroxyl groups of double-stranded RNA (dsRNA), single-stranded RNA (ssRNA), double stranded DNA (dsDNA) and double-stranded DNA:RNA hybrids. dsRNA is phosphorylated more efficiently than dsDNA, and the RNA component of a DNA:RNA hybrid is phosphorylated more efficiently than the DNA component. Appears to have roles in both tRNA splicing and mRNA 3'-end formation. Component of the tRNA splicing endonuclease complex. Phosphorylates the 5'-terminus of the tRNA 3'-exon during tRNA splicing; this phosphorylation event is a prerequisite for the subsequent ligation of the two exon halves and the production of a mature tRNA. Component of the pre-mRNA cleavage complex II (CF-II), which seems to be required for mRNA 3'-end formation. Also phosphorylates the 5'-terminus of exogenously introduced short interfering RNAs (siRNAs), which is a necessary prerequisite for their incorporation into the RNA-induced silencing complex (RISC). However, endogenous siRNAs and microRNAs (miRNAs) that are produced by the cleavage of dsRNA precursors by DICER1 already contain a 5'-phosphate group, so this protein may be dispensible for normal RNA-mediated gene silencing.

219594:P2RX3
gene id: 219594:P2RX3
uniprot id: A0A6J3D4Z8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the P2X receptor family.
messages: Functional P2XRs are organized as homomeric and heteromeric trimers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Receptor for ATP that acts as a ligand-gated ion channel.

219594:DYNC1H1
gene id: 219594:DYNC1H1
uniprot id: A0A6J3D471
names: Similarity
messages: Belongs to the dynein heavy chain family.

219594:PRSS12
gene id: 219594:PRSS12
uniprot id: A0A6J3CSC6
uniprot id: A0A6J3CV43
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:PAM16
gene id: 219594:PAM16
uniprot id: A0A6J3DPQ4
names: Similarity
messages: Belongs to the TIM16/PAM16 family.

219594:LOC116498281
gene id: 219594:LOC116498281
uniprot id: A0A6J3E948
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gastrin/cholecystokinin family.
messages: Secreted

219594:NPY5R
gene id: 219594:NPY5R
uniprot id: A0A6J3D0Z1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for neuropeptide Y and peptide YY. The activity of this receptor is mediated by G proteins that inhibit adenylate cyclase activity. Seems to be associated with food intake. Could be involved in feeding disorders.

219594:TALDO1
gene id: 219594:TALDO1
uniprot id: A0A6J3D668
names: Function
names: Similarity
messages: Belongs to the transaldolase family. Type 1 subfamily.
messages: Catalyzes the rate-limiting step of the non-oxidative phase in the pentose phosphate pathway. Catalyzes the reversible conversion of sedheptulose-7-phosphate and D-glyceraldehyde 3-phosphate into erythrose-4-phosphate and beta-D-fructose 6-phosphate.

219594:UMPS
gene id: 219594:UMPS
uniprot id: A0A6J3D4Y9
names: Similarity
messages: In the C-terminal section; belongs to the OMP decarboxylase family.
messages: In the N-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.

219594:RGR
gene id: 219594:RGR
uniprot id: A0A6J3DAG8
names: Subcellular Location Annotation
messages: Membrane

219594:ZNF488
gene id: 219594:ZNF488
uniprot id: A0A6J3DCW2
names: Subcellular Location Annotation
messages: Nucleus

219594:CPQ
gene id: 219594:CPQ
uniprot id: A0A6J3CE97
names: Subcellular Location Annotation
names: Subunit
messages: Endoplasmic reticulum
messages: Golgi apparatus
messages: Homodimer. The monomeric form is inactive while the homodimer is active.
messages: Lysosome

219594:CPNE4
gene id: 219594:CPNE4
uniprot id: A0A6J3CKJ3
names: Similarity
messages: Belongs to the copine family.

219594:SNX33
gene id: 219594:SNX33
uniprot id: A0A6J3DNT3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sorting nexin family.
messages: Cytoplasmic vesicle membrane

219594:ESRRG
gene id: 219594:ESRRG
uniprot id: A0A6J3CNY7
uniprot id: A0A6J3CPU4
uniprot id: A0A6J3CS37
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR3 subfamily.
messages: Nucleus

219594:WNT5A
gene id: 219594:WNT5A
uniprot id: A0A6J3DFW9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

219594:ATP5ME
gene id: 219594:ATP5ME
uniprot id: A0A6J3EIC3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase e subunit family.
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel.
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain. Minor subunit located with subunit a in the membrane.
messages: Mitochondrion inner membrane

219594:FTSJ3
gene id: 219594:FTSJ3
uniprot id: A0A6J3E6M1
uniprot id: A0A6J3EBP3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. SPB1 subfamily.
messages: Interacts with NIP7.
messages: Probable methyltransferase involved in the processing of the 34S pre-rRNA to 18S rRNA and in 40S ribosomal subunit formation.
messages: nucleolus

219594:FAM193B
gene id: 219594:FAM193B
uniprot id: A0A6J3DUJ5
names: Similarity
messages: Belongs to the FAM193 family.

219594:LOC116497384
gene id: 219594:LOC116497384
uniprot id: A0A6J3E1M6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the intercrine beta (chemokine CC) family.
messages: Secreted

219594:GATC
gene id: 219594:GATC
uniprot id: A0A6J3DY63
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in the mitochondria. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Mitochondrion
messages: Subunit of the heterotrimeric GatCAB amidotransferase (AdT) complex, composed of A (QRSL1), B (GATB) and C (GATC) subunits.

219594:ARL8B
gene id: 219594:ARL8B
uniprot id: A0A6J3DKB1
names: Subcellular Location Annotation
messages: Endosome membrane
messages: Late endosome membrane
messages: Lysosome membrane

219594:EFNA3
gene id: 219594:EFNA3
uniprot id: A0A6J3EAE6
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ephrin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

219594:GSG1
gene id: 219594:GSG1
uniprot id: A0A6J3D831
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSG1 family.
messages: Membrane

219594:PRKN
gene id: 219594:PRKN
uniprot id: A0A6J3CL94
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RBR family. Parkin subfamily.
messages: Mitochondrion
messages: cytosol

219594:LOC116498619
gene id: 219594:LOC116498619
uniprot id: A0A6J3EAF8
uniprot id: A0A6J3EBZ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transcription factor STAT family.
messages: Cytoplasm
messages: Nucleus

219594:IL10
gene id: 219594:IL10
uniprot id: A0A6J3EBH9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IL-10 family.
messages: Immune regulatory cytokine.
messages: Secreted

219594:CNOT7
gene id: 219594:CNOT7
uniprot id: A0A6J3D2E8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CAF1 family.
messages: Nucleus

219594:PIK3CB
gene id: 219594:PIK3CB
uniprot id: A0A6J3DHK5
names: Similarity
messages: Belongs to the PI3/PI4-kinase family. Type III PI4K subfamily.

219594:LOC116496897
gene id: 219594:LOC116496897
uniprot id: A0A6J3E3X3
names: Subcellular Location Annotation
messages: cytoskeleton

219594:ZP1
gene id: 219594:ZP1
uniprot id: A0A6J3D5R8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:LOC116500673
gene id: 219594:LOC116500673
uniprot id: A0A6J3EIJ3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

219594:ADAM23
gene id: 219594:ADAM23
uniprot id: A0A6J3D8P5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:C3H6orf120
gene id: 219594:C3H6orf120
uniprot id: A0A6J3CKI4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0669 family.
messages: Secreted

219594:KALRN
gene id: 219594:KALRN
uniprot id: A0A6J3D331
uniprot id: A0A6J3D336
uniprot id: A0A6J3D339
uniprot id: A0A6J3D5L1
uniprot id: A0A6J3D5L6
uniprot id: A0A6J3D5W2
uniprot id: A0A6J3D5W7
uniprot id: A0A6J3D5X6
uniprot id: A0A6J3D865
uniprot id: A0A6J3D8W9
uniprot id: A0A6J3D8X2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family.
messages: Cytoplasm

219594:LPGAT1
gene id: 219594:LPGAT1
uniprot id: A0A6J3CVH6
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.

219594:LOC116501351
gene id: 219594:LOC116501351
uniprot id: A0A6J3ELL2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

219594:DIP2A
gene id: 219594:DIP2A
uniprot id: A0A6J3D6H8
names: Similarity
messages: Belongs to the DIP2 family.

219594:LHX8
gene id: 219594:LHX8
uniprot id: A0A6J3DGG6
names: Subcellular Location Annotation
messages: Nucleus

219594:IPO11
gene id: 219594:IPO11
uniprot id: A0A6J3EI86
names: Subcellular Location Annotation
messages: Cytoplasm

219594:PSMA7
gene id: 219594:PSMA7
uniprot id: A0A6J3DW84
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1A family.
messages: Cytoplasm
messages: Nucleus
messages: The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits.

219594:MAP6
gene id: 219594:MAP6
uniprot id: A0A6J3EQN2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STOP family.
messages: cytoskeleton

219594:F9
gene id: 219594:F9
uniprot id: A0A6J3DR17
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

219594:LOC116489608
gene id: 219594:LOC116489608
uniprot id: A0A6J3D0J4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the INCENP family.
messages: Midbody
messages: Nucleus
messages: kinetochore
messages: spindle

219594:MICAL3
gene id: 219594:MICAL3
uniprot id: A0A6J3D1U2
uniprot id: A0A6J3D1Y4
uniprot id: A0A6J3D1Z5
uniprot id: A0A6J3D219
uniprot id: A0A6J3D466
uniprot id: A0A6J3D492
uniprot id: A0A6J3D4A5
uniprot id: A0A6J3D4E1
uniprot id: A0A6J3D4L7
uniprot id: A0A6J3D704
uniprot id: A0A6J3D7R5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Mical family.
messages: Cytoplasm

219594:SULF1
gene id: 219594:SULF1
uniprot id: A0A6J3CF76
uniprot id: A0A6J3CH31
uniprot id: A0A6J3CIU7
names: Cofactor
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfatase family.
messages: Binds 1 Ca(2+) ion per subunit.
messages: Cell surface
messages: Endoplasmic reticulum
messages: Golgi stack
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

219594:CHRNB3
gene id: 219594:CHRNB3
uniprot id: A0A6J3EHT9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

219594:CCNI
gene id: 219594:CCNI
uniprot id: A0A6J3CZN7
names: Similarity
messages: Belongs to the cyclin family.

219594:CXXC4
gene id: 219594:CXXC4
uniprot id: A0A6J3CX79
uniprot id: A0A6J3CYC1
names: Subcellular Location Annotation
messages: Cytoplasm

219594:MDFIC
gene id: 219594:MDFIC
uniprot id: A0A6J3DL14
names: Similarity
messages: Belongs to the MDFI family.

219594:CFDP1
gene id: 219594:CFDP1
uniprot id: A0A6J3DQD0
names: Function
names: Subcellular Location Annotation
messages: May play a role during embryogenesis.
messages: kinetochore

219594:LOC116489554
gene id: 219594:LOC116489554
uniprot id: A0A6J3D3T7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COX16 family.
messages: Membrane
messages: Mitochondrion inner membrane

219594:FGF23
gene id: 219594:FGF23
uniprot id: A0A6J3CHE3
names: Similarity
messages: Belongs to the heparin-binding growth factors family.

219594:KIF3A
gene id: 219594:KIF3A
uniprot id: A0A6J3DPE7
uniprot id: A0A6J3DTC9
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

219594:LOC116499216
gene id: 219594:LOC116499216
uniprot id: A0A6J3EEQ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transcriptional coactivator PC4 family.
messages: General coactivator that functions cooperatively with TAFs and mediates functional interactions between upstream activators and the general transcriptional machinery. May be involved in stabilizing the multiprotein transcription complex. Binds single-stranded DNA. Also binds, in vitro, non-specifically to double-stranded DNA (ds DNA).
messages: Nucleus

219594:SSTR1
gene id: 219594:SSTR1
uniprot id: A0A6J3D244
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

219594:AMDHD1
gene id: 219594:AMDHD1
uniprot id: A0A6J3E4R4
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. HutI family.

219594:SH2B3
gene id: 219594:SH2B3
uniprot id: A0A6J3E087
names: Similarity
messages: Belongs to the SH2B adapter family.

219594:ETFA
gene id: 219594:ETFA
uniprot id: A0A6J3DGQ5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ETF alpha-subunit/FixB family.
messages: Binds 1 FAD per dimer.
messages: Heterodimer of an alpha and a beta subunit.
messages: Mitochondrion matrix
messages: The electron transfer flavoprotein serves as a specific electron acceptor for several dehydrogenases, including five acyl-CoA dehydrogenases, glutaryl-CoA and sarcosine dehydrogenase. It transfers the electrons to the main mitochondrial respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase).

219594:LOC116500211
gene id: 219594:LOC116500211
uniprot id: A0A6J3ENB6
names: Function
names: Similarity
messages: Belongs to the apovitellenin family.
messages: Protein component of the very low density lipoprotein (VLDL) of egg-laying females. Potent lipoprotein lipase inhibitor, preventing the loss of triglycerides from VLDL on their way from the liver to the growing oocytes.

219594:ARFGEF2
gene id: 219594:ARFGEF2
uniprot id: A0A6J3DRC3
names: Subcellular Location Annotation
messages: Golgi apparatus
messages: perinuclear region

219594:USP30
gene id: 219594:USP30
uniprot id: A0A6J3DUL1
uniprot id: A0A6J3DZG8
names: Similarity
messages: Belongs to the peptidase C19 family.

219594:SBDS
gene id: 219594:SBDS
uniprot id: A0A6J3E163
names: Function
names: Similarity
messages: Belongs to the SDO1/SBDS family.
messages: Required for the assembly of mature ribosomes and ribosome biogenesis. Together with EFL1, triggers the GTP-dependent release of EIF6 from 60S pre-ribosomes in the cytoplasm, thereby activating ribosomes for translation competence by allowing 80S ribosome assembly and facilitating EIF6 recycling to the nucleus, where it is required for 60S rRNA processing and nuclear export. Required for normal levels of protein synthesis. May play a role in cellular stress resistance. May play a role in cellular response to DNA damage. May play a role in cell proliferation.

219594:TAF1
gene id: 219594:TAF1
uniprot id: A0A6J3DQT7
uniprot id: A0A6J3DRL2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAF1 family.
messages: Nucleus

219594:LOC116502059
gene id: 219594:LOC116502059
uniprot id: A0A6J3EK86
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

219594:LOC116499566
gene id: 219594:LOC116499566
uniprot id: A0A6J3EFW6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

219594:LOC116498519
gene id: 219594:LOC116498519
uniprot id: A0A6J3E4Z7
uniprot id: A0A6J3E6D6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family.
messages: Membrane

219594:TTC26
gene id: 219594:TTC26
uniprot id: A0A6J3EJF3
uniprot id: A0A6J3EPT5
names: Similarity
messages: Belongs to the IFT56 family.

219594:PATL1
gene id: 219594:PATL1
uniprot id: A0A6J3D3X9
names: Similarity
messages: Belongs to the PAT1 family.

219594:SNX9
gene id: 219594:SNX9
uniprot id: A0A6J3CRQ7
uniprot id: A0A6J3CSR5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sorting nexin family.
messages: Cytoplasmic vesicle membrane

219594:TRAK2
gene id: 219594:TRAK2
uniprot id: A0A6J3D464
uniprot id: A0A6J3D6T2
uniprot id: A0A6J3D7C0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the milton family.
messages: Early endosome
messages: Mitochondrion

219594:LOC116502366
gene id: 219594:LOC116502366
uniprot id: A0A6J3EK32
names: Similarity
names: Subunit
messages: Belongs to the histone H3 family.
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

219594:PRDM10
gene id: 219594:PRDM10
uniprot id: A0A6J3E243
uniprot id: A0A6J3E3H9
uniprot id: A0A6J3E6D0
uniprot id: A0A6J3E8B9
uniprot id: A0A6J3E8C5
names: Function
names: Subcellular Location Annotation
messages: May be involved in transcriptional regulation.
messages: Nucleus

219594:CPXM2
gene id: 219594:CPXM2
uniprot id: A0A6J3D6Z7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M14 family.
messages: Secreted

219594:MFN2
gene id: 219594:MFN2
uniprot id: A0A6J3E288
names: Subcellular Location Annotation
messages: Membrane
messages: Mitochondrion outer membrane

219594:ZHX2
gene id: 219594:ZHX2
uniprot id: A0A6J3CHI5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZHX family.
messages: Nucleus

219594:GALT
gene id: 219594:GALT
uniprot id: A0A6J3EHL3
names: Cofactor
names: Similarity
messages: Belongs to the galactose-1-phosphate uridylyltransferase type 1 family.
messages: Binds 1 Fe cation per subunit.

219594:AHSA1
gene id: 219594:AHSA1
uniprot id: A0A6J3D1G9
uniprot id: A0A6J3D474
names: Similarity
messages: Belongs to the AHA1 family.

219594:GTF2F2
gene id: 219594:GTF2F2
uniprot id: A0A6J3DR02
uniprot id: A0A6J3DUS8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TFIIF beta subunit family.
messages: Nucleus
messages: TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB.

219594:MED26
gene id: 219594:MED26
uniprot id: A0A6J3EEH1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Mediator complex subunit 26 family.
messages: Nucleus

219594:CLDN10
gene id: 219594:CLDN10
uniprot id: A0A6J3DZM6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

219594:TRABD2B
gene id: 219594:TRABD2B
uniprot id: A0A6J3D8L8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TIKI family.
messages: Cell membrane
messages: Divalent metal cations. Mn(2+) or Co(2+).
messages: Membrane
messages: Metalloprotease that acts as a negative regulator of the Wnt signaling pathway by mediating the cleavage of the N-terminal residues of a subset of Wnt proteins. Following cleavage, Wnt proteins become oxidized and form large disulfide-bond oligomers, leading to their inactivation.

219594:LOC116488301
gene id: 219594:LOC116488301
uniprot id: A0A6J3CWH5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM47 family.
messages: Membrane

219594:LOC116496453
gene id: 219594:LOC116496453
uniprot id: A0A6J3DVP5
uniprot id: A0A6J3E0N8
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.

219594:FBXO45
gene id: 219594:FBXO45
uniprot id: A0A6J3DCE2
names: Similarity
messages: Belongs to the FBXO45/Fsn family.

219594:MDM4
gene id: 219594:MDM4
uniprot id: A0A6J3EAP6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MDM2/MDM4 family.
messages: Inhibits p53- and p73-mediated cell cycle arrest and apoptosis by binding its transcriptional activation domain.
messages: Nucleus

219594:LOC116486304
gene id: 219594:LOC116486304
uniprot id: A0A6J3CLM7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome c oxidase subunit 6c family.
messages: Component of the cytochrome c oxidase (complex IV, CIV), a multisubunit enzyme composed of 14 subunits. The complex is composed of a catalytic core of 3 subunits MT-CO1, MT-CO2 and MT-CO3, encoded in the mitochondrial DNA, and 11 supernumerary subunits COX4I, COX5A, COX5B, COX6A, COX6B, COX6C, COX7A, COX7B, COX7C, COX8 and NDUFA4, which are encoded in the nuclear genome. The complex exists as a monomer or a dimer and forms supercomplexes (SCs) in the inner mitochondrial membrane with NADH-ubiquinone oxidoreductase (complex I, CI) and ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII), resulting in different assemblies (supercomplex SCI(1)III(2)IV(1) and megacomplex MCI(2)III(2)IV(2)).
messages: Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)). The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
messages: Mitochondrion inner membrane

219594:TTYH3
gene id: 219594:TTYH3
uniprot id: A0A6J3DS11
uniprot id: A0A6J3DU17
uniprot id: A0A6J3DVV0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tweety family.
messages: Cell membrane
messages: Membrane
messages: Probable chloride channel.

219594:AGXT2
gene id: 219594:AGXT2
uniprot id: A0A6J3EDX3
uniprot id: A0A6J3EIS1
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

219594:TPX2
gene id: 219594:TPX2
uniprot id: A0A6J3DS99
uniprot id: A0A6J3DWK6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TPX2 family.
messages: Nucleus
messages: spindle pole

219594:UBE2B
gene id: 219594:UBE2B
uniprot id: A0A6J3DQW8
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

219594:LOC116496366
gene id: 219594:LOC116496366
uniprot id: A0A6J3DVA7
names: Similarity
messages: Belongs to the GST superfamily. Theta family.

219594:SLBP
gene id: 219594:SLBP
uniprot id: A0A6J3CZH0
names: Similarity
messages: Belongs to the SLBP family.

219594:GDF10
gene id: 219594:GDF10
uniprot id: A0A6J3DC45
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TGF-beta family.
messages: Homodimer.
messages: Secreted

219594:KCNN3
gene id: 219594:KCNN3
uniprot id: A0A6J3E9Q7
names: Subcellular Location Annotation
messages: Membrane

219594:COL4A3
gene id: 219594:COL4A3
uniprot id: A0A6J3DCB4
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Type IV collagen is the major structural component of glomerular basement membranes (GBM), forming a 'chicken-wire' meshwork together with laminins, proteoglycans and entactin/nidogen.
messages: basement membrane

219594:IGFBP4
gene id: 219594:IGFBP4
uniprot id: A0A6J3EAK2
names: Caution
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Binds IGF2 more than IGF1.
messages: IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

219594:TEX10
gene id: 219594:TEX10
uniprot id: A0A6J3CIP9
uniprot id: A0A6J3CKD3
names: Similarity
messages: Belongs to the IPI1/TEX10 family.

219594:CORO6
gene id: 219594:CORO6
uniprot id: A0A6J3E4Q5
names: Similarity
messages: Belongs to the WD repeat coronin family.

219594:LOC116502347
gene id: 219594:LOC116502347
uniprot id: A0A6J3ELG7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone H1/H5 family.
messages: Nucleus

219594:TAF5L
gene id: 219594:TAF5L
uniprot id: A0A6J3CTS6
names: Similarity
messages: Belongs to the WD repeat TAF5 family.

219594:REV1
gene id: 219594:REV1
uniprot id: A0A6J3DPP3
uniprot id: A0A6J3DRX3
uniprot id: A0A6J3DVR9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-Y family.
messages: Deoxycytidyl transferase involved in DNA repair. Transfers a dCMP residue from dCTP to the 3'-end of a DNA primer in a template-dependent reaction. May assist in the first step in the bypass of abasic lesions by the insertion of a nucleotide opposite the lesion. Required for normal induction of mutations by physical and chemical agents.
messages: Nucleus

219594:RPF1
gene id: 219594:RPF1
uniprot id: A0A6J3DGS0
names: Subcellular Location Annotation
messages: nucleolus

219594:ELMO2
gene id: 219594:ELMO2
uniprot id: A0A6J3DRA0
uniprot id: A0A6J3DRA5
uniprot id: A0A6J3DVN4
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Involved in cytoskeletal rearrangements required for phagocytosis of apoptotic cells and cell motility. Acts in association with DOCK1 and CRK. Was initially proposed to be required in complex with DOCK1 to activate Rac Rho small GTPases. May enhance the guanine nucleotide exchange factor (GEF) activity of DOCK1.

219594:MXRA8
gene id: 219594:MXRA8
uniprot id: A0A6J3E6U4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

219594:TMPRSS7
gene id: 219594:TMPRSS7
uniprot id: A0A6J3EHG3
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

219594:CD164
gene id: 219594:CD164
uniprot id: A0A6J3CQQ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CD164 family.
messages: Membrane

219594:TP63
gene id: 219594:TP63
uniprot id: A0A6J3DCH9
uniprot id: A0A6J3DGD9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a sequence specific DNA binding transcriptional activator or repressor. The isoforms contain a varying set of transactivation and auto-regulating transactivation inhibiting domains thus showing an isoform specific activity. May be required in conjunction with TP73/p73 for initiation of p53/TP53 dependent apoptosis in response to genotoxic insults and the presence of activated oncogenes.
messages: Belongs to the p53 family.
messages: Binds 1 zinc ion per subunit.
messages: Binds DNA as a homotetramer. Isoform composition of the tetramer may determine transactivation activity.
messages: Nucleus

219594:RPS12
gene id: 219594:RPS12
uniprot id: A0A6J3CU65
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS12 family.

219594:TMEM175
gene id: 219594:TMEM175
uniprot id: A0A6J3EGA4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM175 family.
messages: Membrane

219594:ATG2B
gene id: 219594:ATG2B
uniprot id: A0A6J3D812
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATG2 family.
messages: Endoplasmic reticulum membrane
messages: Lipid droplet
messages: Preautophagosomal structure membrane

219594:DUSP3
gene id: 219594:DUSP3
uniprot id: A0A6J3EB21
names: Function
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.
messages: Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate.

219594:DNAH7
gene id: 219594:DNAH7
uniprot id: A0A6J3D977
names: Similarity
messages: Belongs to the dynein heavy chain family.

219594:ANO8
gene id: 219594:ANO8
uniprot id: A0A6J3E958
uniprot id: A0A6J3EC93
uniprot id: A0A6J3EEF3
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anoctamin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

219594:AP3M1
gene id: 219594:AP3M1
uniprot id: A0A6J3D8L1
names: Similarity
messages: Belongs to the adaptor complexes medium subunit family.

219594:SF3B6
gene id: 219594:SF3B6
uniprot id: A0A6J3CL47
names: Subcellular Location Annotation
messages: Nucleus

219594:TNFRSF19
gene id: 219594:TNFRSF19
uniprot id: A0A6J3EPI0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:LOC116498374
gene id: 219594:LOC116498374
uniprot id: A0A6J3E5W4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the XPG/RAD2 endonuclease family. XPG subfamily.
messages: Nucleus

219594:B4GALT3
gene id: 219594:B4GALT3
uniprot id: A0A6J3DWS9
uniprot id: A0A6J3E108
uniprot id: A0A6J3E2X1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 7 family.
messages: Golgi apparatus membrane
messages: Membrane
messages: Responsible for the synthesis of complex-type N-linked oligosaccharides in many glycoproteins as well as the carbohydrate moieties of glycolipids.

219594:KCNJ1
gene id: 219594:KCNJ1
uniprot id: A0A6J3E7N0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family.
messages: Membrane

219594:FOXP2
gene id: 219594:FOXP2
uniprot id: A0A6J3EI75
names: Subcellular Location Annotation
messages: Nucleus

219594:NQO1
gene id: 219594:NQO1
uniprot id: A0A6J3DJV3
names: Similarity
messages: Belongs to the NAD(P)H dehydrogenase (quinone) family.

219594:LOC116490167
gene id: 219594:LOC116490167
uniprot id: A0A6J3D3I2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. Glucose transporter subfamily.
messages: Cell membrane
messages: Cell projection
messages: Facilitative glucose transporter that can also mediate the uptake of various other monosaccharides across the cell membrane. Mediates the uptake of glucose, 2-deoxyglucose, galactose, mannose, xylose and fucose, and probably also dehydroascorbate. Does not mediate fructose transport.
messages: Perikaryon
messages: Transport is mediated via a series of conformation changes, switching between a conformation where the substrate-binding cavity is accessible from the outside, and a another conformation where it is accessible from the cytoplasm.

219594:VGLL4
gene id: 219594:VGLL4
uniprot id: A0A6J3DE92
uniprot id: A0A6J3DH04
uniprot id: A0A6J3DKD8
names: Function
names: Similarity
messages: Belongs to the vestigial family.
messages: May act as a specific coactivator for the mammalian TEFs.

219594:AKAP1
gene id: 219594:AKAP1
uniprot id: A0A6J3E106
names: Subcellular Location Annotation
messages: Cytoplasm

219594:SPPL3
gene id: 219594:SPPL3
uniprot id: A0A6J3DW18
uniprot id: A0A6J3E042
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A22B family.
messages: Membrane

219594:FAM110C
gene id: 219594:FAM110C
uniprot id: A0A6J3CVE3
names: Similarity
messages: Belongs to the FAM110 family.

219594:CD9
gene id: 219594:CD9
uniprot id: A0A6J3DCT0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Cell membrane
messages: Membrane
messages: extracellular exosome

219594:TIMM13
gene id: 219594:TIMM13
uniprot id: A0A6J3EBQ8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the small Tim family.
messages: Heterohexamer.
messages: Mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space.
messages: Mitochondrion inner membrane
messages: The twin CX3C motif contains 4 conserved Cys residues that form 2 disulfide bonds in the mitochondrial intermembrane space.

219594:LOC116499451
gene id: 219594:LOC116499451
uniprot id: A0A6J3EDT1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IL-1 family.
messages: Secreted

219594:ACAD11
gene id: 219594:ACAD11
uniprot id: A0A6J3CKH9
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

219594:LOC116498221
gene id: 219594:LOC116498221
uniprot id: A0A6J3E407
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

219594:APLNR
gene id: 219594:APLNR
uniprot id: A0A6J3CY13
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

219594:MDH1B
gene id: 219594:MDH1B
uniprot id: A0A6J3D6X9
names: Similarity
messages: Belongs to the LDH/MDH superfamily. MDH type 2 family.

219594:TMEM218
gene id: 219594:TMEM218
uniprot id: A0A6J3E1Y9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM218 family.
messages: May be involved in ciliary biogenesis or function.
messages: Membrane
messages: cilium

219594:PCLO
gene id: 219594:PCLO
uniprot id: A0A6J3EJT0
uniprot id: A0A6J3EJT6
uniprot id: A0A6J3EQ75
uniprot id: A0A6J3EQ81
uniprot id: A0A6J3EQ88
names: Subcellular Location Annotation
messages: Presynaptic active zone

219594:AQP1
gene id: 219594:AQP1
uniprot id: A0A6J3CP66
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

219594:ZNRF4
gene id: 219594:ZNRF4
uniprot id: A0A6J3ED38
names: Subcellular Location Annotation
messages: Membrane

219594:KPNA5
gene id: 219594:KPNA5
uniprot id: A0A6J3CN91
names: Similarity
messages: Belongs to the importin alpha family.

219594:VPS72
gene id: 219594:VPS72
uniprot id: A0A6J3EAV5
names: Function
names: Similarity
messages: Belongs to the VPS72/YL1 family.
messages: Deposition-and-exchange histone chaperone specific for H2AZ1, specifically chaperones H2AZ1 and deposits it into nucleosomes. As component of the SRCAP complex, mediates the ATP-dependent exchange of histone H2AZ1/H2B dimers for nucleosomal H2A/H2B, leading to transcriptional regulation of selected genes by chromatin remodeling.

219594:JPH2
gene id: 219594:JPH2
uniprot id: A0A6J3DSI7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the junctophilin family.
messages: Cell membrane
messages: Endoplasmic reticulum membrane
messages: Junctophilins contribute to the formation of junctional membrane complexes (JMCs) which link the plasma membrane with the endoplasmic or sarcoplasmic reticulum in excitable cells. Provides a structural foundation for functional cross-talk between the cell surface and intracellular calcium release channels.
messages: Membrane

219594:KMT5B
gene id: 219594:KMT5B
uniprot id: A0A6J3D417
names: Subcellular Location Annotation
messages: Chromosome
messages: Nucleus

219594:PDCD10
gene id: 219594:PDCD10
uniprot id: A0A6J3DFE2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PDCD10 family.
messages: Cell membrane
messages: Cytoplasm
messages: Golgi apparatus membrane
messages: Membrane

219594:OSBPL1A
gene id: 219594:OSBPL1A
uniprot id: A0A6J3CGG4
uniprot id: A0A6J3CK15
names: Similarity
messages: Belongs to the OSBP family.

219594:LXN
gene id: 219594:LXN
uniprot id: A0A6J3DIL8
names: Similarity
messages: Belongs to the protease inhibitor I47 (latexin) family.

219594:SNX6
gene id: 219594:SNX6
uniprot id: A0A6J3D1G1
uniprot id: A0A6J3D3Y5
names: Function
names: Similarity
messages: Belongs to the sorting nexin family.
messages: Involved in several stages of intracellular trafficking.

219594:CRYGN
gene id: 219594:CRYGN
uniprot id: A0A6J3CMH8
names: Similarity
names: Subunit
messages: Belongs to the beta/gamma-crystallin family.
messages: Homo/heterodimer, or complexes of higher-order. The structure of beta-crystallin oligomers seems to be stabilized through interactions between the N-terminal arms.

219594:FAM174C
gene id: 219594:FAM174C
uniprot id: A0A6J3ECK8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAM174 family.
messages: Membrane

219594:INPP4A
gene id: 219594:INPP4A
uniprot id: A0A6J3CJ14
uniprot id: A0A6J3CJ63
uniprot id: A0A6J3CJ84
uniprot id: A0A6J3CKJ0
uniprot id: A0A6J3CKK1
uniprot id: A0A6J3CKL5
uniprot id: A0A6J3CLM5
uniprot id: A0A6J3CNT0
uniprot id: A0A6J3CNU2
uniprot id: A0A6J3CQ14
uniprot id: A0A6J3CQ40
names: Similarity
messages: Belongs to the inositol 3,4-bisphosphate 4-phosphatase family.

219594:CENPL
gene id: 219594:CENPL
uniprot id: A0A6J3DDD7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CENP-L/IML3 family.
messages: Nucleus

219594:DDX51
gene id: 219594:DDX51
uniprot id: A0A6J3DUF1
names: Domain
names: Function
names: Similarity
messages: Belongs to the DEAD box helicase family.
messages: RNA helicase.
messages: The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.

219594:EIF4ENIF1
gene id: 219594:EIF4ENIF1
uniprot id: A0A6J3DUI6
uniprot id: A0A6J3DWC2
uniprot id: A0A6J3DYM2
uniprot id: A0A6J3E0F5
names: Subcellular Location Annotation
messages: Cytoplasm

219594:ALDOC
gene id: 219594:ALDOC
uniprot id: A0A6J3E1A3
names: Similarity
messages: Belongs to the class I fructose-bisphosphate aldolase family.

219594:DNM2
gene id: 219594:DNM2
uniprot id: A0A6J3EFU4
names: Similarity
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.

219594:CELF4
gene id: 219594:CELF4
uniprot id: A0A6J3EDM5
uniprot id: A0A6J3EF19
uniprot id: A0A6J3EIG8
uniprot id: A0A6J3EIH3
uniprot id: A0A6J3EIU6
uniprot id: A0A6J3EIV0
uniprot id: A0A6J3EIV5
uniprot id: A0A6J3EKF0
uniprot id: A0A6J3EKF5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CELF/BRUNOL family.
messages: Nucleus

219594:LOC116498730
gene id: 219594:LOC116498730
uniprot id: A0A6J3EA79
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:HOXA9
gene id: 219594:HOXA9
uniprot id: A0A6J3CJC2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Abd-B homeobox family.
messages: Nucleus
messages: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

219594:MRPS24
gene id: 219594:MRPS24
uniprot id: A0A6J3E9N8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Mitochondrion

219594:EFEMP1
gene id: 219594:EFEMP1
uniprot id: A0A6J3CT84
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:C8G
gene id: 219594:C8G
uniprot id: A0A6J3E430
names: Subcellular Location Annotation
messages: Secreted

219594:NMU
gene id: 219594:NMU
uniprot id: A0A6J3D2G3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NmU family.
messages: Secreted

219594:LOC116498203
gene id: 219594:LOC116498203
uniprot id: A0A6J3EAE5
names: Similarity
messages: Belongs to the peptidase C1 family.

219594:EIF2S1
gene id: 219594:EIF2S1
uniprot id: A0A6J3D5Q7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eIF-2-alpha family.
messages: Stress granule

219594:GOLT1B
gene id: 219594:GOLT1B
uniprot id: A0A6J3ELE4
uniprot id: A0A6J3EMU6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GOT1 family.
messages: Golgi apparatus membrane
messages: May be involved in fusion of ER-derived transport vesicles with the Golgi complex.
messages: Membrane

219594:LOC116492935
gene id: 219594:LOC116492935
uniprot id: A0A6J3DH48
names: Similarity
messages: Belongs to the CDC50/LEM3 family.

219594:PPME1
gene id: 219594:PPME1
uniprot id: A0A6J3CYZ0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the AB hydrolase superfamily.
messages: Binds PPP2CA and PPP2CB.
messages: Demethylates proteins that have been reversibly carboxymethylated. Demethylates PPP2CB (in vitro) and PPP2CA. Binding to PPP2CA displaces the manganese ion and inactivates the enzyme.

219594:RTN4
gene id: 219594:RTN4
uniprot id: A0A6J3CNU5
uniprot id: A0A6J3CR23
uniprot id: A0A6J3CS34
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

219594:TSTA3
gene id: 219594:TSTA3
uniprot id: A0A6J3CFJ5
uniprot id: A0A6J3CH66
names: Function
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. Fucose synthase subfamily.
messages: Catalyzes the two-step NADP-dependent conversion of GDP-4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction.

219594:FAM149B1
gene id: 219594:FAM149B1
uniprot id: A0A6J3DBX7
uniprot id: A0A6J3DCE1
names: Similarity
messages: Belongs to the FAM149 family.

219594:LOC116496542
gene id: 219594:LOC116496542
uniprot id: A0A6J3DW56
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: High affinity receptor for urotensin-2 and urotensin-2B. The activity of this receptor is mediated by a G-protein that activate a phosphatidylinositol-calcium second messenger system.
messages: Membrane

219594:LOC116495014
gene id: 219594:LOC116495014
uniprot id: A0A6J3DTU9
names: Similarity
messages: Belongs to the LECT2/MIM-1 family.

219594:FREM2
gene id: 219594:FREM2
uniprot id: A0A6J3ELA4
names: Similarity
messages: Belongs to the FRAS1 family.

219594:CAV1
gene id: 219594:CAV1
uniprot id: A0A6J3DT32
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the caveolin family.
messages: Cell membrane
messages: Golgi apparatus membrane
messages: May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity.
messages: Membrane
messages: caveola

219594:SLC35B1
gene id: 219594:SLC35B1
uniprot id: A0A6J3E945
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleotide-sugar transporter family. SLC35B subfamily.
messages: Membrane

219594:CACNG1
gene id: 219594:CACNG1
uniprot id: A0A6J3DZH1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily.
messages: Component of a calcium channel complex consisting of a pore-forming alpha subunit (CACNA1S) and the ancillary subunits CACNB1 or CACNB2, CACNG1 and CACNA2D1. The channel complex contains alpha, beta, gamma and delta subunits in a 1:1:1:1 ratio, i.e. it contains either CACNB1 or CACNB2.
messages: Membrane
messages: Regulatory subunit of the voltage-gated calcium channel that gives rise to L-type calcium currents in skeletal muscle. Regulates channel inactivation kinetics.
messages: sarcolemma

219594:CNKSR1
gene id: 219594:CNKSR1
uniprot id: A0A6J3E8Z5
names: Similarity
messages: Belongs to the CNKSR family.

219594:OPRL1
gene id: 219594:OPRL1
uniprot id: A0A6J3DWN2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Cytoplasmic vesicle
messages: G-protein coupled opioid receptor that functions as receptor for the endogenous neuropeptide nociceptin. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. Signaling via G proteins mediates inhibition of adenylate cyclase activity and calcium channel activity. Arrestins modulate signaling via G proteins and mediate the activation of alternative signaling pathways that lead to the activation of MAP kinases. Plays a role in modulating nociception and the perception of pain. Plays a role in the regulation of locomotor activity by the neuropeptide nociceptin.
messages: Membrane
messages: Vesicle

219594:SARDH
gene id: 219594:SARDH
uniprot id: A0A6J3DZI7
names: Similarity
messages: Belongs to the GcvT family.

219594:DYRK1A
gene id: 219594:DYRK1A
uniprot id: A0A6J3DG81
names: Similarity
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MNB/DYRK subfamily.

219594:DUPD1
gene id: 219594:DUPD1
uniprot id: A0A6J3D792
names: Function
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.
messages: Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate.

219594:ERBB4
gene id: 219594:ERBB4
uniprot id: A0A6J3D904
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. EGF receptor subfamily.
messages: Membrane

219594:CLDN5
gene id: 219594:CLDN5
uniprot id: A0A6J3DUW4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

219594:GPN3
gene id: 219594:GPN3
uniprot id: A0A6J3DUH0
uniprot id: A0A6J3DYK9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GPN-loop GTPase family.
messages: Binds to RNA polymerase II (RNAPII).
messages: Small GTPase required for proper localization of RNA polymerase II (RNAPII). May act at an RNAP assembly step prior to nuclear import.
messages: Small GTPase required for proper nuclear import of RNA polymerase II and III (RNAPII and RNAPIII). May act at an RNAP assembly step prior to nuclear import.

219594:PSEN1
gene id: 219594:PSEN1
uniprot id: A0A6J3D3D5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase A22A family.
messages: Cytoplasmic granule
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Homodimer.
messages: Membrane
messages: Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors.
messages: Synapse
messages: The PAL motif is required for normal active site conformation.
messages: axon
messages: neuron projection

219594:PTER
gene id: 219594:PTER
uniprot id: A0A6J3CIX4
names: Caution
names: Cofactor
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Phosphotriesterase family.
messages: Binds 2 divalent metal cations per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:CORO2B
gene id: 219594:CORO2B
uniprot id: A0A6J3DHT6
uniprot id: A0A6J3DNA8
names: Similarity
messages: Belongs to the WD repeat coronin family.

219594:PGM5
gene id: 219594:PGM5
uniprot id: A0A6J3EGE8
names: Similarity
messages: Belongs to the phosphohexose mutase family.

219594:LOC116491905
gene id: 219594:LOC116491905
uniprot id: A0A6J3DCC6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SEC16 family.
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Plays a role in the organization of the endoplasmic reticulum exit sites (ERES), also known as transitional endoplasmic reticulum (tER). Required for secretory cargo traffic from the endoplasmic reticulum to the Golgi apparatus.
messages: SEC16A and SEC16B are each present in multiple copies in a heteromeric complex.

219594:WNT3A
gene id: 219594:WNT3A
uniprot id: A0A6J3CJ03
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

219594:LOC116488076
gene id: 219594:LOC116488076
uniprot id: A0A6J3CQD4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Toll-like receptor family.
messages: Cooperates with LY96 to mediate the innate immune response to bacterial lipoproteins and other microbial cell wall components. Cooperates with TLR1 or TLR6 to mediate the innate immune response to bacterial lipoproteins or lipopeptides. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response.
messages: Membrane

219594:TFAP2E
gene id: 219594:TFAP2E
uniprot id: A0A6J3E829
names: Similarity
messages: Belongs to the AP-2 family.

219594:SAG
gene id: 219594:SAG
uniprot id: A0A6J3DIG1
names: Similarity
messages: Belongs to the arrestin family.

219594:HAPLN4
gene id: 219594:HAPLN4
uniprot id: A0A6J3EEI1
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:INTS8
gene id: 219594:INTS8
uniprot id: A0A6J3CLY2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Integrator subunit 8 family.
messages: Nucleus

219594:HYI
gene id: 219594:HYI
uniprot id: A0A6J3DCU5
names: Function
names: Similarity
messages: Belongs to the hyi family.
messages: Catalyzes the reversible isomerization between hydroxypyruvate and 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde).

219594:KCNC2
gene id: 219594:KCNC2
uniprot id: A0A6J3E9A2
uniprot id: A0A6J3E9C5
uniprot id: A0A6J3E9F2
uniprot id: A0A6J3ECD0
uniprot id: A0A6J3ECF7
uniprot id: A0A6J3ECZ1
uniprot id: A0A6J3EEN0
names: Subcellular Location Annotation
messages: Membrane

219594:MTFMT
gene id: 219594:MTFMT
uniprot id: A0A6J3DL32
names: Similarity
messages: Belongs to the Fmt family.

219594:LOC116493517
gene id: 219594:LOC116493517
uniprot id: A0A6J3DLF7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DUOXA family.
messages: Membrane

219594:NCLN
gene id: 219594:NCLN
uniprot id: A0A6J3EE99
names: Function
names: Similarity
messages: Belongs to the nicastrin family.
messages: May antagonize Nodal signaling and subsequent organization of axial structures during mesodermal patterning.

219594:CCNO
gene id: 219594:CCNO
uniprot id: A0A6J3EHJ7
names: Similarity
messages: Belongs to the cyclin family.

219594:RPL13
gene id: 219594:RPL13
uniprot id: A0A6J3DIT3
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL13 family.

219594:PDE1A
gene id: 219594:PDE1A
uniprot id: A0A6J3DB55
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family. PDE1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

219594:OASL
gene id: 219594:OASL
uniprot id: A0A6J3DKH9
names: Similarity
messages: Belongs to the 2-5A synthase family.

219594:POU3F4
gene id: 219594:POU3F4
uniprot id: A0A6J3DRU6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the POU transcription factor family. Class-3 subfamily.
messages: Nucleus

219594:CACNB3
gene id: 219594:CACNB3
uniprot id: A0A6J3EAD2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calcium channel beta subunit family.
messages: Cytoplasm

219594:SLC16A4
gene id: 219594:SLC16A4
uniprot id: A0A6J3E714
names: Subcellular Location Annotation
messages: Membrane

219594:MAF
gene id: 219594:MAF
uniprot id: A0A6J3DPJ1
names: Similarity
messages: Belongs to the bZIP family. Maf subfamily.

219594:SCUBE1
gene id: 219594:SCUBE1
uniprot id: A0A6J3EB28
uniprot id: A0A6J3EB39
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

219594:STK17A
gene id: 219594:STK17A
uniprot id: A0A6J3CJK5
names: Similarity
messages: Belongs to the protein kinase superfamily.

219594:NPC1L1
gene id: 219594:NPC1L1
uniprot id: A0A6J3E869
names: Similarity
messages: Belongs to the patched family.

219594:EXOSC3
gene id: 219594:EXOSC3
uniprot id: A0A6J3DCZ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRP40 family.
messages: Cytoplasm
messages: nucleolus

219594:HMGCS1
gene id: 219594:HMGCS1
uniprot id: A0A6J3EDN0
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. HMG-CoA synthase family.
messages: Catalyzes the condensation of acetyl-CoA with acetoacetyl-CoA to form HMG-CoA.

219594:ABCA13
gene id: 219594:ABCA13
uniprot id: A0A6J3CEZ4
names: Subcellular Location Annotation
messages: Membrane

219594:LOC116490345
gene id: 219594:LOC116490345
uniprot id: A0A6J3D4E6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COA8 family.
messages: Mitochondrion inner membrane

219594:SLC9A3R2
gene id: 219594:SLC9A3R2
uniprot id: A0A6J3DSQ9
names: Function
names: Subcellular Location Annotation
messages: Endomembrane system
messages: Scaffold protein that connects plasma membrane proteins with members of the ezrin/moesin/radixin family and thereby helps to link them to the actin cytoskeleton and to regulate their surface expression.

219594:GALNT7
gene id: 219594:GALNT7
uniprot id: A0A6J3CVN4
uniprot id: A0A6J3CW40
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
messages: Golgi apparatus membrane
messages: Membrane

219594:SAMM50
gene id: 219594:SAMM50
uniprot id: A0A6J3D070
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SAM50/omp85 family.
messages: Mitochondrion outer membrane

219594:MAPK8IP1
gene id: 219594:MAPK8IP1
uniprot id: A0A6J3D063
uniprot id: A0A6J3D2J9
uniprot id: A0A6J3D539
uniprot id: A0A6J3D616
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the JIP scaffold family.
messages: Cytoplasm

219594:KATNA1
gene id: 219594:KATNA1
uniprot id: A0A6J3CQ67
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATPase activity is stimulated by microtubules, which promote homooligomerization. ATP-dependent microtubule severing is stimulated by interaction with KATNB1.
messages: Belongs to the AAA ATPase family. Katanin p60 subunit A1 subfamily.
messages: Can homooligomerize into hexameric rings, which may be promoted by interaction with microtubules. Interacts with KATNB1, which may serve as a targeting subunit.
messages: Catalytic subunit of a complex which severs microtubules in an ATP-dependent manner. Microtubule severing may promote rapid reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation.
messages: Cytoplasm
messages: centrosome
messages: spindle
messages: spindle pole

219594:NQO2
gene id: 219594:NQO2
uniprot id: A0A6J3CQT0
names: Similarity
messages: Belongs to the NAD(P)H dehydrogenase (quinone) family.

219594:LHX9
gene id: 219594:LHX9
uniprot id: A0A6J3DAP0
uniprot id: A0A6J3DGC5
names: Subcellular Location Annotation
messages: Nucleus

219594:ADSS1
gene id: 219594:ADSS1
uniprot id: A0A6J3D169
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Component of the purine nucleotide cycle (PNC), which interconverts IMP and AMP to regulate the nucleotide levels in various tissues, and which contributes to glycolysis and ammoniagenesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP.
messages: Component of the purine nucleotide cycle (PNC), which interconverts IMP and AMP to regulate the nucleotide levels in various tissues, and which contributes to glycolysis and ammoniagenesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis.

219594:OIP5
gene id: 219594:OIP5
uniprot id: A0A6J3D0B3
names: Function
names: Subcellular Location Annotation
messages: Nucleus
messages: Required for recruitment of CENPA to centromeres and normal chromosome segregation during mitosis.
messages: centromere

219594:CTSB
gene id: 219594:CTSB
uniprot id: A0A6J3CTX8
names: Similarity
messages: Belongs to the peptidase C1 family.

219594:HCRT
gene id: 219594:HCRT
uniprot id: A0A6J3E9U5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the orexin family.
messages: Endoplasmic reticulum
messages: Rough endoplasmic reticulum
messages: Synapse
messages: Vesicle

219594:GBA2
gene id: 219594:GBA2
uniprot id: A0A6J3EDY3
names: Function
names: Similarity
messages: Belongs to the non-lysosomal glucosylceramidase family.
messages: Non-lysosomal glucosylceramidase that catalyzes the hydrolysis of glucosylceramide (GlcCer) to free glucose and ceramide.

219594:NETO2
gene id: 219594:NETO2
uniprot id: A0A6J3DIK6
uniprot id: A0A6J3DP29
uniprot id: A0A6J3DPQ2
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:ATP6V1H
gene id: 219594:ATP6V1H
uniprot id: A0A6J3CIY1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the V-ATPase H subunit family.
messages: Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments.
messages: V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex.

219594:CHD1L
gene id: 219594:CHD1L
uniprot id: A0A6J3E5T5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNF2/RAD54 helicase family.
messages: Nucleus

219594:LOC116490554
gene id: 219594:LOC116490554
uniprot id: A0A6J3D5M5
uniprot id: A0A6J3D860
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protease inhibitor I39 (alpha-2-macroglobulin) family.
messages: Secreted

219594:S1PR3
gene id: 219594:S1PR3
uniprot id: A0A6J3EHP0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

219594:KYNU
gene id: 219594:KYNU
uniprot id: A0A6J3D6I4
uniprot id: A0A6J3D718
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the kynureninase family.
messages: Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3-hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3-hydroxyanthranilic acid (3-OHAA), respectively.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:MND1
gene id: 219594:MND1
uniprot id: A0A6J3CV16
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MND1 family.
messages: Nucleus
messages: Required for proper homologous chromosome pairing and efficient cross-over and intragenic recombination during meiosis.

219594:MOGAT2
gene id: 219594:MOGAT2
uniprot id: A0A6J3EHQ9
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the diacylglycerol acyltransferase family.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:QTRT1
gene id: 219594:QTRT1
uniprot id: A0A6J3EFY7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Catalytic subunit of the queuine tRNA-ribosyltransferase (TGT) that catalyzes the base-exchange of a guanine (G) residue with queuine (Q) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming queuine, allowing a nucleophilic attack on the C1' of the ribose to form the product.
messages: Cytoplasm
messages: Heterodimer of a catalytic subunit QTRT1 and an accessory subunit QTRT2.
messages: Mitochondrion outer membrane

219594:CALHM5
gene id: 219594:CALHM5
uniprot id: A0A6J3CME7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CALHM family.
messages: Membrane

219594:PCBD2
gene id: 219594:PCBD2
uniprot id: A0A6J3DSZ8
names: Similarity
messages: Belongs to the pterin-4-alpha-carbinolamine dehydratase family.

219594:MLLT11
gene id: 219594:MLLT11
uniprot id: A0A6J3EE07
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MLLT11 family.
messages: Nucleus
messages: centrosome

219594:TBCD
gene id: 219594:TBCD
uniprot id: A0A6J3DXW9
names: Similarity
messages: Belongs to the TBCD family.

219594:ARAP3
gene id: 219594:ARAP3
uniprot id: A0A6J3DM26
names: Subcellular Location Annotation
messages: Cytoplasm

219594:POU4F2
gene id: 219594:POU4F2
uniprot id: A0A6J3CXB1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the POU transcription factor family.
messages: Nucleus

219594:TTC3
gene id: 219594:TTC3
uniprot id: A0A6J3CV33
uniprot id: A0A6J3CXU4
names: Subcellular Location Annotation
messages: Cytoplasm

219594:ANTXR2
gene id: 219594:ANTXR2
uniprot id: A0A6J3CYN1
uniprot id: A0A6J3CZQ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATR family.
messages: Membrane

219594:RPS15A
gene id: 219594:RPS15A
uniprot id: A0A6J3DQW1
names: Similarity
messages: Belongs to the universal ribosomal protein uS8 family.

219594:EXOC6
gene id: 219594:EXOC6
uniprot id: A0A6J3DA87
names: Function
names: Similarity
messages: Belongs to the SEC15 family.
messages: Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.

219594:SUPT6H
gene id: 219594:SUPT6H
uniprot id: A0A6J3DYV1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPT6 family.
messages: Nucleus
messages: Transcription elongation factor that enhances transcription elongation by RNA polymerase II (RNAPII).

219594:ST6GALNAC4
gene id: 219594:ST6GALNAC4
uniprot id: A0A6J3E203
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

219594:RMND1
gene id: 219594:RMND1
uniprot id: A0A6J3CR08
names: Similarity
messages: Belongs to the RMD1/sif2 family.

219594:UBA6
gene id: 219594:UBA6
uniprot id: A0A6J3CU24
names: Similarity
messages: Belongs to the ubiquitin-activating E1 family.

219594:ADAMTS5
gene id: 219594:ADAMTS5
uniprot id: A0A6J3DD22
names: Caution
names: Cofactor
names: Subcellular Location Annotation
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

219594:LOC116498220
gene id: 219594:LOC116498220
uniprot id: A0A6J3E8D4
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

219594:BMPR1B
gene id: 219594:BMPR1B
uniprot id: A0A6J3CZM0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
messages: Membrane

219594:LOC116502361
gene id: 219594:LOC116502361
uniprot id: A0A6J3ELI0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2B family.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

219594:B3GNT7
gene id: 219594:B3GNT7
uniprot id: A0A6J3DJ50
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane

219594:CHD5
gene id: 219594:CHD5
uniprot id: A0A6J3E0L8
uniprot id: A0A6J3E204
uniprot id: A0A6J3E4U3
uniprot id: A0A6J3E5M1
uniprot id: A0A6J3E6P9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNF2/RAD54 helicase family.
messages: Nucleus

219594:CCDC126
gene id: 219594:CCDC126
uniprot id: A0A6J3CI46
names: Subcellular Location Annotation
messages: Secreted

219594:LOC116494751
gene id: 219594:LOC116494751
uniprot id: A0A6J3DRX6
names: Subcellular Location Annotation
messages: Secreted

219594:SNX14
gene id: 219594:SNX14
uniprot id: A0A6J3CRA2
uniprot id: A0A6J3CSB1
names: Similarity
messages: Belongs to the sorting nexin family.

219594:GRIA1
gene id: 219594:GRIA1
uniprot id: A0A6J3DND1
uniprot id: A0A6J3DQP6
uniprot id: A0A6J3DSQ8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Receptor for glutamate that functions as a ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system.

219594:FBXL5
gene id: 219594:FBXL5
uniprot id: A0A6J3CSF1
uniprot id: A0A6J3CUR1
names: Subcellular Location Annotation
messages: perinuclear region

219594:LOC116489453
gene id: 219594:LOC116489453
uniprot id: A0A6J3D2A6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ITPRIP family.
messages: Membrane

219594:AK1
gene id: 219594:AK1
uniprot id: A0A6J3E3R7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family. AK1 subfamily.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Also displays broad nucleoside diphosphate kinase activity. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Monomer.

219594:LOC116487046
gene id: 219594:LOC116487046
uniprot id: A0A6J3CRD0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. Very large inducible GTPase (VLIG) family.
messages: Nucleus

219594:SOX11
gene id: 219594:SOX11
uniprot id: A0A6J3CP70
names: Subcellular Location Annotation
messages: Nucleus

219594:SPTSSA
gene id: 219594:SPTSSA
uniprot id: A0A6J3D3L6
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

219594:CLDN20
gene id: 219594:CLDN20
uniprot id: A0A6J3CQ21
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

219594:FABP3
gene id: 219594:FABP3
uniprot id: A0A6J3E378
names: Similarity
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.

219594:AP3M2
gene id: 219594:AP3M2
uniprot id: A0A6J3EAA8
names: Similarity
messages: Belongs to the adaptor complexes medium subunit family.

219594:ALMS1
gene id: 219594:ALMS1
uniprot id: A0A6J3CXL5
names: Subcellular Location Annotation
messages: centrosome

219594:CCNE1
gene id: 219594:CCNE1
uniprot id: A0A6J3DQY7
names: Similarity
messages: Belongs to the cyclin family.

219594:CYGB
gene id: 219594:CYGB
uniprot id: A0A6J3DXQ1
names: Similarity
messages: Belongs to the globin family.

219594:TSN
gene id: 219594:TSN
uniprot id: A0A6J3DA63
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the translin family.
messages: DNA-binding protein that specifically recognizes consensus sequences at the breakpoint junctions in chromosomal translocations, mostly involving immunoglobulin (Ig)/T-cell receptor gene segments. Seems to recognize single-stranded DNA ends generated by staggered breaks occurring at recombination hot spots.
messages: Exhibits both single-stranded and double-stranded endoribonuclease activity. May act as an activator of RNA-induced silencing complex (RISC) by facilitating endonucleolytic cleavage of the siRNA passenger strand.
messages: Nucleus
messages: Ring-shaped heterooctamer of six TSN and two TSNAX subunits, DNA/RNA binding occurs inside the ring.

219594:NIFK
gene id: 219594:NIFK
uniprot id: A0A6J3D3Y0
names: Subcellular Location Annotation
messages: nucleolus

219594:GSTCD
gene id: 219594:GSTCD
uniprot id: A0A6J3D1A4
uniprot id: A0A6J3D2F3
names: Similarity
messages: Belongs to the GSTCD family.

219594:LOC116496434
gene id: 219594:LOC116496434
uniprot id: A0A6J3DZR9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:TMEM214
gene id: 219594:TMEM214
uniprot id: A0A6J3CQN0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TMEM214 family.
messages: Constitutively interacts with CASP4; required for the localization of procaspase 4 to the ER.
messages: Critical mediator, in cooperation with CASP4, of endoplasmic reticulum-stress induced apoptosis. Required or the activation of CASP4 following endoplasmic reticulum stress.
messages: Endoplasmic reticulum membrane
messages: Membrane

219594:LOC116500914
gene id: 219594:LOC116500914
uniprot id: A0A6J3EJL7
uniprot id: A0A6J3EJS4
uniprot id: A0A6J3ELA8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type I cytokine receptor family. Type 2 subfamily.
messages: Membrane

219594:TDRD7
gene id: 219594:TDRD7
uniprot id: A0A6J3EFE6
uniprot id: A0A6J3EKK4
names: Subcellular Location Annotation
messages: Cytoplasm

219594:LOC116489592
gene id: 219594:LOC116489592
uniprot id: A0A6J3D0G5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the beta type-B retroviral polymerase family. HERV class-II K(HML-2) pol subfamily.
messages: Nucleus

219594:MED19
gene id: 219594:MED19
uniprot id: A0A6J3D599
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 19 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex.
messages: Nucleus

219594:OGFR
gene id: 219594:OGFR
uniprot id: A0A6J3DX88
uniprot id: A0A6J3DYA7
names: Similarity
messages: Belongs to the opioid growth factor receptor family.

219594:SLC34A1
gene id: 219594:SLC34A1
uniprot id: A0A6J3DSI0
names: Similarity
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Belongs to the SLC34A transporter family.
messages: Cell membrane
messages: Membrane

219594:TGFB2
gene id: 219594:TGFB2
uniprot id: A0A6J3CTW1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TGF-beta family.
messages: Homodimer; disulfide-linked.
messages: Precursor of the Latency-associated peptide (LAP) and Transforming growth factor beta-2 (TGF-beta-2) chains, which constitute the regulatory and active subunit of TGF-beta-2, respectively.
messages: extracellular matrix

219594:ELOA
gene id: 219594:ELOA
uniprot id: A0A6J3E4F3
uniprot id: A0A6J3E7Z9
names: Subcellular Location Annotation
messages: Nucleus

219594:DDR2
gene id: 219594:DDR2
uniprot id: A0A6J3D9Q2
uniprot id: A0A6J3DDC0
names: Subcellular Location Annotation
messages: Membrane

219594:FPGS
gene id: 219594:FPGS
uniprot id: A0A6J3DYF7
names: Cofactor
names: Function
names: Similarity
messages: A monovalent cation.
messages: Belongs to the folylpolyglutamate synthase family.
messages: Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis.

219594:PYCR3
gene id: 219594:PYCR3
uniprot id: A0A6J3CGD7
names: Similarity
messages: Belongs to the pyrroline-5-carboxylate reductase family.

219594:SLC13A1
gene id: 219594:SLC13A1
uniprot id: A0A6J3E7Y5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC13A/DASS transporter (TC 2.A.47) family. NADC subfamily.
messages: Membrane

219594:DDA1
gene id: 219594:DDA1
uniprot id: A0A6J3EBY4
names: Similarity
messages: Belongs to the DDA1 family.

219594:PPARGC1A
gene id: 219594:PPARGC1A
uniprot id: A0A6J3CTI2
uniprot id: A0A6J3CYL3
names: Subcellular Location Annotation
messages: PML body

219594:KRT8
gene id: 219594:KRT8
uniprot id: A0A6J3EBR2
names: Similarity
messages: Belongs to the intermediate filament family.

219594:PDSS1
gene id: 219594:PDSS1
uniprot id: A0A6J3CFX8
uniprot id: A0A6J3CM67
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

219594:LOC116486779
gene id: 219594:LOC116486779
uniprot id: A0A6J3CKZ9
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily.

219594:DTX4
gene id: 219594:DTX4
uniprot id: A0A6J3D0U1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Deltex family.
messages: Cytoplasm

219594:LOC116490259
gene id: 219594:LOC116490259
uniprot id: A0A6J3D1K5
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

219594:TSEN2
gene id: 219594:TSEN2
uniprot id: A0A6J3DL98
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA-intron endonuclease family.
messages: Constitutes one of the two catalytic subunit of the tRNA-splicing endonuclease complex, a complex responsible for identification and cleavage of the splice sites in pre-tRNA. It cleaves pre-tRNA at the 5'- and 3'-splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3'-cyclic phosphate and 5'-OH termini. There are no conserved sequences at the splice sites, but the intron is invariably located at the same site in the gene, placing the splice sites an invariant distance from the constant structural features of the tRNA body.
messages: Nucleus

219594:PLA2G4A
gene id: 219594:PLA2G4A
uniprot id: A0A6J3DFJ1
names: Domain
messages: The N-terminal C2 domain associates with lipid membranes upon calcium binding.

219594:PELI1
gene id: 219594:PELI1
uniprot id: A0A6J3CS33
uniprot id: A0A6J3CUE0
names: Similarity
messages: Belongs to the pellino family.

219594:AXIN1
gene id: 219594:AXIN1
uniprot id: A0A6J3DW39
uniprot id: A0A6J3DX06
names: Subcellular Location Annotation
messages: Cytoplasm

219594:LOC116492237
gene id: 219594:LOC116492237
uniprot id: A0A6J3DEZ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the hcp beta-lactamase family.
messages: Mitochondrion intermembrane space
messages: Required for assembly of mitochondrial respiratory chain complexes.

219594:ARSI
gene id: 219594:ARSI
uniprot id: A0A6J3DT98
names: Similarity
messages: Belongs to the sulfatase family.

219594:PIF1
gene id: 219594:PIF1
uniprot id: A0A6J3DGT2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the helicase family. PIF1 subfamily.
messages: DNA-dependent ATPase and 5'-3' DNA helicase required for the maintenance of both mitochondrial and nuclear genome stability.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mitochondrion
messages: Monomer.
messages: Nucleus

219594:LOC116500796
gene id: 219594:LOC116500796
uniprot id: A0A6J3EKQ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

219594:RAD18
gene id: 219594:RAD18
uniprot id: A0A6J3DIK7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RAD18 family.
messages: Nucleus

219594:DCAF10
gene id: 219594:DCAF10
uniprot id: A0A6J3EEY8
uniprot id: A0A6J3EIQ9
uniprot id: A0A6J3EKD1
names: Function
names: Similarity
messages: Belongs to the WD repeat DCAF10 family.
messages: May function as a substrate receptor for CUL4-DDB1 E3 ubiquitin-protein ligase complex.

219594:FGG
gene id: 219594:FGG
uniprot id: A0A6J3CW85
names: Subcellular Location Annotation
names: Subunit
messages: Heterohexamer; disulfide linked. Contains 2 sets of 3 non-identical chains (alpha, beta and gamma). The 2 heterotrimers are in head to head conformation with the N-termini in a small central domain.
messages: Secreted

219594:C15H16orf91
gene id: 219594:C15H16orf91
uniprot id: A0A6J3DU68
names: Similarity
messages: Belongs to the UQCC4 family.

219594:SFT2D3
gene id: 219594:SFT2D3
uniprot id: A0A6J3DG38
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SFT2 family.
messages: May be involved in fusion of retrograde transport vesicles derived from an endocytic compartment with the Golgi complex.
messages: Membrane

219594:LOC116502169
gene id: 219594:LOC116502169
uniprot id: A0A6J3EKL6
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.

219594:GLYATL3
gene id: 219594:GLYATL3
uniprot id: A0A6J3CSW9
names: Similarity
messages: Belongs to the glycine N-acyltransferase family.

219594:MSH2
gene id: 219594:MSH2
uniprot id: A0A6J3CMF2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA mismatch repair MutS family.
messages: Component of the post-replicative DNA mismatch repair system (MMR).
messages: Nucleus

219594:NT5DC3
gene id: 219594:NT5DC3
uniprot id: A0A6J3D771
names: Cofactor
names: Similarity
messages: Belongs to the 5'(3')-deoxyribonucleotidase family.
messages: Binds 1 Mg(2+) ion per subunit.

219594:LOC116499524
gene id: 219594:LOC116499524
uniprot id: A0A6J3EFS3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dwarfin/SMAD family.
messages: Cytoplasm
messages: Nucleus

219594:LOC116498569
gene id: 219594:LOC116498569
uniprot id: A0A6J3EBM9
names: Subcellular Location Annotation
messages: Membrane

219594:SCOC
gene id: 219594:SCOC
uniprot id: A0A6J3CYX3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SCOC family.
messages: Positive regulator of amino acid starvation-induced autophagy.
messages: trans-Golgi network

219594:PPP4R2
gene id: 219594:PPP4R2
uniprot id: A0A6J3DKE3
names: Similarity
messages: Belongs to the PPP4R2 family.

219594:LOC116501125
gene id: 219594:LOC116501125
uniprot id: A0A6J3EKL1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.
messages: Membrane

219594:LOC116501284
gene id: 219594:LOC116501284
uniprot id: A0A6J3EMS2
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:MDFIC2
gene id: 219594:MDFIC2
uniprot id: A0A6J3DED6
uniprot id: A0A6J3DIE1
names: Similarity
messages: Belongs to the MDFI family.

219594:TNRC6C
gene id: 219594:TNRC6C
uniprot id: A0A6J3DVD6
uniprot id: A0A6J3DVE2
uniprot id: A0A6J3DX82
uniprot id: A0A6J3DX90
uniprot id: A0A6J3DZJ1
uniprot id: A0A6J3DZJ7
uniprot id: A0A6J3E0A8
uniprot id: A0A6J3E1H2
names: Similarity
messages: Belongs to the GW182 family.

219594:ASPM
gene id: 219594:ASPM
uniprot id: A0A6J3DDF0
names: Subcellular Location Annotation
messages: Nucleus

219594:OSGEPL1
gene id: 219594:OSGEPL1
uniprot id: A0A6J3D3Z3
uniprot id: A0A6J3D9W2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 divalent metal cation per subunit.
messages: Mitochondrion
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in mitochondrial tRNAs that read codons beginning with adenine. Probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. Involved in mitochondrial genome maintenance.

219594:UCN3
gene id: 219594:UCN3
uniprot id: A0A6J3CEL6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sauvagine/corticotropin-releasing factor/urotensin I family.
messages: Binds with high affinity to CRF receptors 2-alpha and 2-beta.
messages: Secreted
messages: Suppresses food intake, delays gastric emptying and decreases heat-induced edema. Might represent an endogenous ligand for maintaining homeostasis after stress.

219594:LOC116494561
gene id: 219594:LOC116494561
uniprot id: A0A6J3DQY6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the POU transcription factor family.
messages: Nucleus

219594:PCBD1
gene id: 219594:PCBD1
uniprot id: A0A6J3DD07
names: Similarity
messages: Belongs to the pterin-4-alpha-carbinolamine dehydratase family.

219594:ILVBL
gene id: 219594:ILVBL
uniprot id: A0A6J3EFV8
names: Similarity
messages: Belongs to the TPP enzyme family.

219594:LOC116485654
gene id: 219594:LOC116485654
uniprot id: A0A6J3CHZ3
names: Subcellular Location Annotation
messages: Nucleus

219594:NT5C3A
gene id: 219594:NT5C3A
uniprot id: A0A6J3CHY2
uniprot id: A0A6J3CKX2
uniprot id: A0A6J3CKX6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrimidine 5'-nucleotidase family.
messages: Cytoplasm

219594:PHKA1
gene id: 219594:PHKA1
uniprot id: A0A6J3DS05
uniprot id: A0A6J3DT13
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Although the final Cys may be farnesylated, the terminal tripeptide is probably not removed, and the C-terminus is not methylated.
messages: Belongs to the phosphorylase b kinase regulatory chain family.
messages: Cell membrane
messages: Membrane
messages: Phosphorylase b kinase catalyzes the phosphorylation of serine in certain substrates, including troponin I. The alpha chain may bind calmodulin.

219594:PSIP1
gene id: 219594:PSIP1
uniprot id: A0A6J3ECY5
uniprot id: A0A6J3EJS3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HDGF family.
messages: Nucleus

219594:MAP3K6
gene id: 219594:MAP3K6
uniprot id: A0A6J3E3Z6
names: Similarity
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.

219594:CPNE5
gene id: 219594:CPNE5
uniprot id: A0A6J3E5J4
names: Similarity
messages: Belongs to the copine family.

219594:LOC116486753
gene id: 219594:LOC116486753
uniprot id: A0A6J3CJD6
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily.

219594:TAPT1
gene id: 219594:TAPT1
uniprot id: A0A6J3CU75
uniprot id: A0A6J3CZ90
uniprot id: A0A6J3D0C2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAPT1 family.
messages: Membrane

219594:ARPC3
gene id: 219594:ARPC3
uniprot id: A0A6J3DZ77
names: Similarity
messages: Belongs to the ARPC3 family.

219594:CLGN
gene id: 219594:CLGN
uniprot id: A0A6J3CYK4
uniprot id: A0A6J3CYW8
names: Similarity
messages: Belongs to the calreticulin family.

219594:CPSF6
gene id: 219594:CPSF6
uniprot id: A0A6J3CI48
uniprot id: A0A6J3CI58
uniprot id: A0A6J3CI75
uniprot id: A0A6J3CKU9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRM CPSF6/7 family.
messages: Nucleus

219594:ATP11B
gene id: 219594:ATP11B
uniprot id: A0A6J3DDK0
uniprot id: A0A6J3DDL0
uniprot id: A0A6J3DGA3
uniprot id: A0A6J3DGA7
uniprot id: A0A6J3DHI8
uniprot id: A0A6J3DJ48
uniprot id: A0A6J3DJ57
uniprot id: A0A6J3DJP8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.
messages: Membrane

219594:LOC116494598
gene id: 219594:LOC116494598
uniprot id: A0A6J3DLU3
uniprot id: A0A6J3DP62
uniprot id: A0A6J3DR38
uniprot id: A0A6J3DT31
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UIF family.
messages: Nucleus speckle
messages: nucleoplasm

219594:KCNU1
gene id: 219594:KCNU1
uniprot id: A0A6J3E9S0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the potassium channel family. Calcium-activated (TC 1.A.1.3) subfamily. KCa1.1/KCNMA1 sub-subfamily.
messages: Membrane

219594:LOC116488650
gene id: 219594:LOC116488650
uniprot id: A0A6J3CVU9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEC23/SEC24 family. SEC24 subfamily.
messages: COPII-coated vesicle membrane
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: cytosol

219594:PLPPR3
gene id: 219594:PLPPR3
uniprot id: A0A6J3EDV0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PA-phosphatase related phosphoesterase family.
messages: Membrane

219594:TTC30B
gene id: 219594:TTC30B
uniprot id: A0A6J3D8A6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TTC30/dfy-1/fleer family.
messages: Required for polyglutamylation of axonemal tubulin. Plays a role in anterograde intraflagellar transport (IFT), the process by which cilia precursors are transported from the base of the cilium to the site of their incorporation at the tip.
messages: cilium

219594:PRCP
gene id: 219594:PRCP
uniprot id: A0A6J3EI04
names: Similarity
messages: Belongs to the peptidase S28 family.

219594:S1PR1
gene id: 219594:S1PR1
uniprot id: A0A6J3DF96
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

219594:CCNF
gene id: 219594:CCNF
uniprot id: A0A6J3DUP7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cyclin family.
messages: Nucleus
messages: centriole
messages: perinuclear region

219594:SH3YL1
gene id: 219594:SH3YL1
uniprot id: A0A6J3CPK5
uniprot id: A0A6J3CQC2
names: Similarity
messages: Belongs to the SH3YL1 family.

219594:CAPN6
gene id: 219594:CAPN6
uniprot id: A0A6J3DKZ7
names: Similarity
messages: Belongs to the peptidase C2 family.

219594:RAP2A
gene id: 219594:RAP2A
uniprot id: A0A6J3D3X2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Ras family.
messages: Endosome membrane
messages: Recycling endosome membrane

219594:MRPL51
gene id: 219594:MRPL51
uniprot id: A0A6J3EN06
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mL51 family.
messages: Mitochondrion

219594:REN
gene id: 219594:REN
uniprot id: A0A6J3EC33
names: Similarity
messages: Belongs to the peptidase A1 family.

219594:LOC116485665
gene id: 219594:LOC116485665
uniprot id: A0A6J3CG55
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

219594:SLC33A1
gene id: 219594:SLC33A1
uniprot id: A0A6J3DF82
names: Subcellular Location Annotation
messages: Membrane

219594:GLG1
gene id: 219594:GLG1
uniprot id: A0A6J3DNP4
names: Subcellular Location Annotation
messages: Golgi apparatus membrane
messages: Golgi outpost
messages: Membrane
messages: microtubule organizing center

219594:QRSL1
gene id: 219594:QRSL1
uniprot id: A0A6J3CSL5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in the mitochondria. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Mitochondrion
messages: Subunit of the heterotrimeric GatCAB amidotransferase (AdT) complex, composed of A (QRSL1), B (GATB) and C (GATC) subunits.

219594:TRH
gene id: 219594:TRH
uniprot id: A0A6J3DIJ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRH family.
messages: Functions as a regulator of the biosynthesis of TSH in the anterior pituitary gland and as a neurotransmitter/ neuromodulator in the central and peripheral nervous systems.
messages: Secreted

219594:IFNGR1
gene id: 219594:IFNGR1
uniprot id: A0A6J3CSP1
names: Similarity
messages: Belongs to the type II cytokine receptor family.

219594:ALG12
gene id: 219594:ALG12
uniprot id: A0A6J3CQU3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 22 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

219594:KCNK13
gene id: 219594:KCNK13
uniprot id: A0A6J3CXJ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
messages: Membrane

219594:ITPR3
gene id: 219594:ITPR3
uniprot id: A0A6J3E5N5
uniprot id: A0A6J3E740
uniprot id: A0A6J3EAR6
uniprot id: A0A6J3ECA3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the InsP3 receptor family.
messages: Endoplasmic reticulum membrane
messages: Homotetramer.
messages: Membrane
messages: Receptor for inositol 1,4,5-trisphosphate, a second messenger that mediates the release of intracellular calcium.
messages: The receptor contains a calcium channel in its C-terminal extremity. Its large N-terminal cytoplasmic region has the ligand-binding site in the N-terminus and modulatory sites in the middle portion immediately upstream of the channel region.

219594:LOC116499256
gene id: 219594:LOC116499256
uniprot id: A0A6J3ED44
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Nucleus

219594:CUEDC2
gene id: 219594:CUEDC2
uniprot id: A0A6J3DDF9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CUEDC2 family.
messages: Cytoplasm
messages: Nucleus

219594:ERH
gene id: 219594:ERH
uniprot id: A0A6J3D1L4
names: Function
names: Similarity
messages: Belongs to the E(R) family.
messages: May have a role in the cell cycle.

219594:LOC116495848
gene id: 219594:LOC116495848
uniprot id: A0A6J3DXR9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BPI/LBP/Plunc superfamily. BPI/LBP family.
messages: Monomer. Homodimer; disulfide-linked.
messages: Secreted
messages: The N- and C-terminal barrels adopt an identical fold despite having only 13% of conserved residues.
messages: The N-terminal region may be exposed to the interior of the granule, whereas the C-terminal portion may be embedded in the membrane. During phagocytosis and degranulation, proteases may be released and activated and cleave BPI at the junction of the N- and C-terminal portions of the molecule, providing controlled release of the N-terminal antibacterial fragment when bacteria are ingested.
messages: The cytotoxic action of BPI is limited to many species of Gram-negative bacteria; this specificity may be explained by a strong affinity of the very basic N-terminal half for the negatively charged lipopolysaccharides that are unique to the Gram-negative bacterial outer envelope.

219594:RRP8
gene id: 219594:RRP8
uniprot id: A0A6J3EJQ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RRP8 family.
messages: Probable methyltransferase required to silence rDNA.
messages: nucleolus

219594:TMEM9
gene id: 219594:TMEM9
uniprot id: A0A6J3EBJ7
names: Similarity
messages: Belongs to the TMEM9 family.

219594:SERPINI1
gene id: 219594:SERPINI1
uniprot id: A0A6J3DHE9
names: Similarity
messages: Belongs to the serpin family.

219594:LOC116500326
gene id: 219594:LOC116500326
uniprot id: A0A6J3EBT1
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:LOC116488502
gene id: 219594:LOC116488502
uniprot id: A0A6J3CSC2
uniprot id: A0A6J3CXE8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 1 family. NDST subfamily.
messages: Membrane

219594:GHSR
gene id: 219594:GHSR
uniprot id: A0A6J3DIR2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

219594:LOC116496599
gene id: 219594:LOC116496599
uniprot id: A0A6J3E2H8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TVP23 family.
messages: Membrane

219594:LOC116501342
gene id: 219594:LOC116501342
uniprot id: A0A6J3EHQ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

219594:LOC116486814
gene id: 219594:LOC116486814
uniprot id: A0A6J3CJN6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome P450 family.
messages: Endoplasmic reticulum membrane

219594:ARL1
gene id: 219594:ARL1
uniprot id: A0A6J3CXI4
names: Similarity
messages: Belongs to the small GTPase superfamily. Arf family.

219594:LOC116501424
gene id: 219594:LOC116501424
uniprot id: A0A6J3ELX3
names: Function
names: Similarity
messages: Belongs to the ATPase alpha/beta chains family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

219594:LOC116493183
gene id: 219594:LOC116493183
uniprot id: A0A6J3DI67
uniprot id: A0A6J3DJG5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:PPP2R5E
gene id: 219594:PPP2R5E
uniprot id: A0A6J3CXD5
uniprot id: A0A6J3D286
names: Similarity
messages: Belongs to the phosphatase 2A regulatory subunit B56 family.

219594:PSD2
gene id: 219594:PSD2
uniprot id: A0A6J3DQM3
uniprot id: A0A6J3DSN5
uniprot id: A0A6J3DUD2
names: Subcellular Location Annotation
messages: ruffle membrane

219594:PPIE
gene id: 219594:PPIE
uniprot id: A0A6J3E338
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family. PPIase E subfamily.
messages: Catalyzes the cis-trans isomerization of proline imidic peptide bonds in proteins.

219594:LOC116502029
gene id: 219594:LOC116502029
uniprot id: A0A6J3EK45
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.
messages: cytoskeleton

219594:SSBP1
gene id: 219594:SSBP1
uniprot id: A0A6J3DQ26
names: Subcellular Location Annotation
messages: mitochondrion nucleoid

219594:TSC22D3
gene id: 219594:TSC22D3
uniprot id: A0A6J3DP34
uniprot id: A0A6J3DR14
uniprot id: A0A6J3DT05
names: Similarity
messages: Belongs to the TSC-22/Dip/Bun family.

219594:RAPSN
gene id: 219594:RAPSN
uniprot id: A0A6J3D1H5
uniprot id: A0A6J3D3V3
names: Similarity
messages: Belongs to the RAPsyn family.

219594:NIPAL2
gene id: 219594:NIPAL2
uniprot id: A0A6J3CHZ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NIPA family.
messages: Membrane

219594:OLFML2A
gene id: 219594:OLFML2A
uniprot id: A0A6J3E424
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:THBD
gene id: 219594:THBD
uniprot id: A0A6J3CKP0
names: Caution
names: Function
names: Subunit
messages: Interacts with ITGAL, ITGAM and ITGB2.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Thrombomodulin is a specific endothelial cell receptor that forms a 1:1 stoichiometric complex with thrombin. This complex is responsible for the conversion of protein C to the activated protein C (protein Ca). Once evolved, protein Ca scissions the activated cofactors of the coagulation mechanism, factor Va and factor VIIIa, and thereby reduces the amount of thrombin generated.

219594:COPG1
gene id: 219594:COPG1
uniprot id: A0A6J3DIX2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the COPG family.
messages: COPI-coated vesicle membrane
messages: Cytoplasm
messages: Golgi apparatus membrane
messages: Membrane
messages: Oligomeric complex.
messages: The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.

219594:PPP1R21
gene id: 219594:PPP1R21
uniprot id: A0A6J3CU49
names: Subcellular Location Annotation
messages: Early endosome
messages: Endosome

219594:ETV6
gene id: 219594:ETV6
uniprot id: A0A6J3E6Y2
uniprot id: A0A6J3EBY8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

219594:CCR7
gene id: 219594:CCR7
uniprot id: A0A6J3E6U8
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

219594:RNASEH2B
gene id: 219594:RNASEH2B
uniprot id: A0A6J3D6I9
uniprot id: A0A6J3D9V5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase H2 subunit B family.
messages: Non catalytic subunit of RNase H2, an endonuclease that specifically degrades the RNA of RNA:DNA hybrids. Participates in DNA replication, possibly by mediating the removal of lagging-strand Okazaki fragment RNA primers during DNA replication. Mediates the excision of single ribonucleotides from DNA:RNA duplexes.
messages: Nucleus
messages: The RNase H2 complex is a heterotrimer composed of the catalytic subunit RNASEH2A and the non-catalytic subunits RNASEH2B and RNASEH2C.

219594:TERT
gene id: 219594:TERT
uniprot id: A0A6J3CHX2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the reverse transcriptase family. Telomerase subfamily.
messages: Nucleus
messages: Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. It elongates telomeres. It is a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme.
messages: telomere

219594:CHD2
gene id: 219594:CHD2
uniprot id: A0A6J3DK35
names: Subcellular Location Annotation
messages: Nucleus

219594:ITM2A
gene id: 219594:ITM2A
uniprot id: A0A6J3DRF6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ITM2 family.
messages: Membrane

219594:DCT
gene id: 219594:DCT
uniprot id: A0A6J3E978
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tyrosinase family.
messages: Melanosome membrane
messages: Membrane

219594:LOC116489416
gene id: 219594:LOC116489416
uniprot id: A0A6J3CZS0
names: Similarity
messages: Belongs to the CD225/Dispanin family.

219594:LOC116496679
gene id: 219594:LOC116496679
uniprot id: A0A6J3E0X2
names: Function
names: Subcellular Location Annotation
messages: Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I.
messages: Mitochondrion inner membrane

219594:SLC35C1
gene id: 219594:SLC35C1
uniprot id: A0A6J3D1E2
names: Subcellular Location Annotation
messages: Membrane

219594:TMEM41A
gene id: 219594:TMEM41A
uniprot id: A0A6J3DIM3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM41 family.
messages: Membrane

219594:SLC16A5
gene id: 219594:SLC16A5
uniprot id: A0A6J3E0B0
names: Subcellular Location Annotation
messages: Membrane

219594:POLD3
gene id: 219594:POLD3
uniprot id: A0A6J3EP76
names: Subcellular Location Annotation
messages: Nucleus

219594:ARVCF
gene id: 219594:ARVCF
uniprot id: A0A6J3DV19
uniprot id: A0A6J3DWV6
uniprot id: A0A6J3DWW1
uniprot id: A0A6J3DWW5
uniprot id: A0A6J3DZ64
uniprot id: A0A6J3DZ70
uniprot id: A0A6J3DZ76
uniprot id: A0A6J3DZX2
uniprot id: A0A6J3E103
uniprot id: A0A6J3E109
names: Similarity
messages: Belongs to the beta-catenin family.

219594:NDUFB1
gene id: 219594:NDUFB1
uniprot id: A0A6J3D1T4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFB1 subunit family.
messages: Complex I is composed of 45 different subunits.
messages: Mitochondrion inner membrane

219594:ID4
gene id: 219594:ID4
uniprot id: A0A6J3CIB1
names: Subcellular Location Annotation
messages: Nucleus

219594:NUP62CL
gene id: 219594:NUP62CL
uniprot id: A0A6J3DT08
names: Similarity
messages: Belongs to the nucleoporin NSP1/NUP62 family.

219594:PRC1
gene id: 219594:PRC1
uniprot id: A0A6J3DGR4
uniprot id: A0A6J3DJC5
uniprot id: A0A6J3DKT2
uniprot id: A0A6J3DM86
uniprot id: A0A6J3DMT1
names: Similarity
messages: Belongs to the MAP65/ASE1 family.

219594:ACSS3
gene id: 219594:ACSS3
uniprot id: A0A6J3ENF0
uniprot id: A0A6J3EPW6
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

219594:STK11
gene id: 219594:STK11
uniprot id: A0A6J3EDH6
names: Similarity
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. LKB1 subfamily.

219594:CDADC1
gene id: 219594:CDADC1
uniprot id: A0A6J3EKD2
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.

219594:LOC116485583
gene id: 219594:LOC116485583
uniprot id: A0A6J3CHR8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

219594:DRC7
gene id: 219594:DRC7
uniprot id: A0A6J3DQ39
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DRC7 family.
messages: cilium axoneme
messages: flagellum
messages: flagellum axoneme

219594:ADAM12
gene id: 219594:ADAM12
uniprot id: A0A6J3DBR8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:PARD6G
gene id: 219594:PARD6G
uniprot id: A0A6J3CLN4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAR6 family.
messages: Cytoplasm
messages: tight junction

219594:ALDH9A1
gene id: 219594:ALDH9A1
uniprot id: A0A6J3DE44
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

219594:COQ5
gene id: 219594:COQ5
uniprot id: A0A6J3E0B5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Component of a multi-subunit COQ enzyme complex, composed of at least COQ3, COQ4, COQ5, COQ6, COQ7 and COQ9.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methyltransferase required for the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2).
messages: Mitochondrion inner membrane

219594:LOC116500662
gene id: 219594:LOC116500662
uniprot id: A0A6J3EDB2
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.

219594:SPPL2B
gene id: 219594:SPPL2B
uniprot id: A0A6J3E8G7
uniprot id: A0A6J3EBH8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A22B family.
messages: Endosome membrane
messages: Lysosome membrane
messages: Membrane

219594:PPP4R3B
gene id: 219594:PPP4R3B
uniprot id: A0A6J3CK95
uniprot id: A0A6J3CLS1
names: Similarity
messages: Belongs to the SMEK family.

219594:LOC116488244
gene id: 219594:LOC116488244
uniprot id: A0A6J3CR89
uniprot id: A0A6J3CTJ3
uniprot id: A0A6J3CU08
names: Similarity
messages: Belongs to the PACS family.

219594:SETD3
gene id: 219594:SETD3
uniprot id: A0A6J3D1Z9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class V-like SAM-binding methyltransferase superfamily. SETD3 actin-histidine methyltransferase family.
messages: Cytoplasm

219594:PPP1R3C
gene id: 219594:PPP1R3C
uniprot id: A0A6J3D7S8
names: Domain
names: Function
names: Subunit
messages: Acts as a glycogen-targeting subunit for PP1 and regulates its activity. Activates glycogen synthase, reduces glycogen phosphorylase activity and limits glycogen breakdown.
messages: Interacts with PPP1CC catalytic subunit of PP1 and associates with glycogen. Forms complexes with glycogen phosphorylase, glycogen synthase and phosphorylase kinase which is necessary for its regulation of PP1 activity.
messages: The N-terminal region is required for binding to PP1, the central region is required for binding to glycogen and the C-terminal region is required for binding to glycogen phosphorylase glycogen synthase and phosphorylase kinase.

219594:EXOSC9
gene id: 219594:EXOSC9
uniprot id: A0A6J3CYR0
names: Subcellular Location Annotation
messages: Cytoplasm

219594:ADGRG7
gene id: 219594:ADGRG7
uniprot id: A0A6J3DIW5
names: Subcellular Location Annotation
messages: Membrane

219594:SRSF1
gene id: 219594:SRSF1
uniprot id: A0A6J3E5I6
names: Similarity
messages: Belongs to the splicing factor SR family.

219594:LOC116502217
gene id: 219594:LOC116502217
uniprot id: A0A6J3ER93
names: Similarity
messages: Belongs to the folate receptor family.

219594:HTRA2
gene id: 219594:HTRA2
uniprot id: A0A6J3CYZ5
names: Similarity
messages: Belongs to the peptidase S1C family.

219594:TMEM132B
gene id: 219594:TMEM132B
uniprot id: A0A6J3DZB9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM132 family.
messages: Membrane

219594:RARA
gene id: 219594:RARA
uniprot id: A0A6J3EBR7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR1 subfamily.
messages: Nucleus

219594:LOC116488910
gene id: 219594:LOC116488910
uniprot id: A0A6J3CUN7
uniprot id: A0A6J3CWZ3
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

219594:PIGB
gene id: 219594:PIGB
uniprot id: A0A6J3DMR3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 22 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

219594:MRPL14
gene id: 219594:MRPL14
uniprot id: A0A6J3CPK1
names: Similarity
messages: Belongs to the universal ribosomal protein uL14 family.

219594:PIAS2
gene id: 219594:PIAS2
uniprot id: A0A6J3EF63
uniprot id: A0A6J3EKI9
names: Similarity
messages: Belongs to the PIAS family.

219594:TRAPPC9
gene id: 219594:TRAPPC9
uniprot id: A0A6J3CH08
uniprot id: A0A6J3CIS5
names: Similarity
messages: Belongs to the NIBP family.

219594:DYNC2H1
gene id: 219594:DYNC2H1
uniprot id: A0A6J3DGS6
names: Similarity
messages: Belongs to the dynein heavy chain family.

219594:ELAC1
gene id: 219594:ELAC1
uniprot id: A0A6J3EIA6
names: Subunit
messages: Homodimer.

219594:PRLR
gene id: 219594:PRLR
uniprot id: A0A6J3EEC4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type I cytokine receptor family. Type 1 subfamily.
messages: Membrane
messages: The WSXWS motif appears to be necessary for proper protein folding and thereby efficient intracellular transport and cell-surface receptor binding.
messages: The box 1 motif is required for JAK interaction and/or activation.
messages: This is a receptor for the anterior pituitary hormone prolactin.

219594:LSM4
gene id: 219594:LSM4
uniprot id: A0A6J3EEN5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the snRNP Sm proteins family.
messages: Binds specifically to the 3'-terminal U-tract of U6 snRNA.
messages: LSm subunits form a heteromer with a doughnut shape.
messages: Nucleus

219594:LOC116499130
gene id: 219594:LOC116499130
uniprot id: A0A6J3E917
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.

219594:LOC116501009
gene id: 219594:LOC116501009
uniprot id: A0A6J3ELK5
names: Similarity
messages: Belongs to the universal ribosomal protein uL22 family.

219594:LOC116490550
gene id: 219594:LOC116490550
uniprot id: A0A6J3D320
uniprot id: A0A6J3D8V9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:RPL39
gene id: 219594:RPL39
uniprot id: A0A6J3DKQ0
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL39 family.

219594:ANXA11
gene id: 219594:ANXA11
uniprot id: A0A6J3DA39
names: Domain
names: Similarity
messages: A pair of annexin repeats may form one binding site for calcium and phospholipid.
messages: Belongs to the annexin family.

219594:KCNC4
gene id: 219594:KCNC4
uniprot id: A0A6J3E6N6
uniprot id: A0A6J3EBQ5
names: Subcellular Location Annotation
messages: Membrane

219594:TSNARE1
gene id: 219594:TSNARE1
uniprot id: A0A6J3CK57
uniprot id: A0A6J3CLV1
names: Similarity
messages: Belongs to the syntaxin family.

219594:ALPL
gene id: 219594:ALPL
uniprot id: A0A6J3E7Z2
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the alkaline phosphatase family.
messages: Binds 1 Mg(2+) ion.
messages: Binds 2 Zn(2+) ions.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

219594:MATK
gene id: 219594:MATK
uniprot id: A0A6J3E947
names: Similarity
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.

219594:IPPK
gene id: 219594:IPPK
uniprot id: A0A6J3DJP7
names: Domain
names: Function
names: Similarity
messages: Belongs to the IPK1 type 2 family.
messages: Phosphorylates Ins(1,3,4,5,6)P5 at position 2 to form Ins(1,2,3,4,5,6)P6 (InsP6 or phytate).
messages: The EXKPK motif is conserved in inositol-pentakisphosphate 2-kinases of both family 1 and 2.

219594:OSBPL6
gene id: 219594:OSBPL6
uniprot id: A0A6J3D383
uniprot id: A0A6J3D5R6
uniprot id: A0A6J3D648
uniprot id: A0A6J3D8B3
uniprot id: A0A6J3D924
names: Similarity
messages: Belongs to the OSBP family.

219594:STEAP4
gene id: 219594:STEAP4
uniprot id: A0A6J3CKX4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STEAP family.
messages: Endosome membrane
messages: Membrane

219594:LOC116490193
gene id: 219594:LOC116490193
uniprot id: A0A6J3D1A0
uniprot id: A0A6J3D3Y7
uniprot id: A0A6J3D743
names: Similarity
messages: Belongs to the Luc7 family.

219594:HOXB1
gene id: 219594:HOXB1
uniprot id: A0A6J3EA16
names: Subcellular Location Annotation
messages: Nucleus

219594:PTDSS2
gene id: 219594:PTDSS2
uniprot id: A0A6J3D3E9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phosphatidyl serine synthase family.
messages: Catalyzes a base-exchange reaction in which the polar head group of phosphatidylethanolamine (PE) is replaced by L-serine.
messages: Endoplasmic reticulum membrane
messages: Membrane

219594:HPGD
gene id: 219594:HPGD
uniprot id: A0A6J3D1V8
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

219594:DBNDD1
gene id: 219594:DBNDD1
uniprot id: A0A6J3DMG6
names: Similarity
messages: Belongs to the dysbindin family.

219594:LOC116490455
gene id: 219594:LOC116490455
uniprot id: A0A6J3D4S9
uniprot id: A0A6J3D7D8
names: Similarity
messages: Belongs to the cytochrome P450 family.

219594:GNAL
gene id: 219594:GNAL
uniprot id: A0A6J3CNB8
names: Similarity
messages: Belongs to the G-alpha family. G(s) subfamily.

219594:ST14
gene id: 219594:ST14
uniprot id: A0A6J3E2G5
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

219594:MON1A
gene id: 219594:MON1A
uniprot id: A0A6J3DHC1
uniprot id: A0A6J3DIL0
names: Function
names: Similarity
messages: Belongs to the MON1/SAND family.
messages: Plays an important role in membrane trafficking through the secretory apparatus.

219594:LOC116499165
gene id: 219594:LOC116499165
uniprot id: A0A6J3E7N8
uniprot id: A0A6J3EEG7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat Groucho/TLE family.
messages: Nucleus

219594:SLC40A1
gene id: 219594:SLC40A1
uniprot id: A0A6J3DA34
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Basolateral cell membrane
messages: Belongs to the ferroportin (FP) (TC 2.A.100) family. SLC40A subfamily.
messages: Lateral cell membrane
messages: May be involved in iron transport and iron homeostasis.
messages: Membrane

219594:TLR4
gene id: 219594:TLR4
uniprot id: A0A6J3DZP2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Toll-like receptor family.
messages: Membrane

219594:NEK9
gene id: 219594:NEK9
uniprot id: A0A6J3D1A2
uniprot id: A0A6J3D1D6
names: Similarity
messages: Belongs to the protein kinase superfamily. NEK Ser/Thr protein kinase family. NIMA subfamily.

219594:CEP55
gene id: 219594:CEP55
uniprot id: A0A6J3DCY8
names: Subcellular Location Annotation
messages: Cytoplasm

219594:RPE65
gene id: 219594:RPE65
uniprot id: A0A6J3DB77
names: Cofactor
names: Similarity
messages: Belongs to the carotenoid oxygenase family.
messages: Binds 1 Fe(2+) ion per subunit.

219594:LOC116486705
gene id: 219594:LOC116486705
uniprot id: A0A6J3CQ59
names: Similarity
names: Subunit
messages: Belongs to the avian keratin family.
messages: The avian keratins (F-ker, S-ker, C-ker and B-ker) are a complex mixture of very similar polypeptides.

219594:VPS26C
gene id: 219594:VPS26C
uniprot id: A0A6J3EKY6
names: Similarity
messages: Belongs to the VPS26 family.

219594:LOC116500767
gene id: 219594:LOC116500767
uniprot id: A0A6J3EIN0
names: Caution
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:YAF2
gene id: 219594:YAF2
uniprot id: A0A6J3CUZ3
names: Subcellular Location Annotation
messages: Nucleus

219594:TOR4A
gene id: 219594:TOR4A
uniprot id: A0A6J3E0C6
names: Similarity
messages: Belongs to the ClpA/ClpB family. Torsin subfamily.

219594:ZBTB8OS
gene id: 219594:ZBTB8OS
uniprot id: A0A6J3E3S6
uniprot id: A0A6J3E575
uniprot id: A0A6J3E843
names: Similarity
names: Subunit
messages: Belongs to the archease family.
messages: Component of the tRNA-splicing ligase complex.

219594:TIPIN
gene id: 219594:TIPIN
uniprot id: A0A6J3DK41
uniprot id: A0A6J3DLL0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CSM3 family.
messages: Nucleus
messages: Plays an important role in the control of DNA replication and the maintenance of replication fork stability.

219594:DHTKD1
gene id: 219594:DHTKD1
uniprot id: A0A6J3DZ98
names: Similarity
messages: Belongs to the alpha-ketoglutarate dehydrogenase family.

219594:KATNB1
gene id: 219594:KATNB1
uniprot id: A0A6J3DM34
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the WD repeat KATNB1 family.
messages: Cytoplasm
messages: Interacts with KATNA1. This interaction enhances the microtubule binding and severing activity of KATNA1 and also targets this activity to the centrosome.
messages: Participates in a complex which severs microtubules in an ATP-dependent manner. May act to target the enzymatic subunit of this complex to sites of action such as the centrosome. Microtubule severing may promote rapid reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation.
messages: centrosome
messages: cytoskeleton
messages: spindle
messages: spindle pole

219594:LOC116499251
gene id: 219594:LOC116499251
uniprot id: A0A6J3EET7
names: Similarity
messages: Belongs to the perilipin family.

219594:CD40LG
gene id: 219594:CD40LG
uniprot id: A0A6J3DP37
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a ligand for integrins, specifically ITGA5:ITGB1 and ITGAV:ITGB3; both integrins and the CD40 receptor are required for activation of CD40-CD40LG signaling, which have cell-type dependent effects, such as B-cell activation, NF-kappa-B signaling and anti-apoptotic signaling.
messages: Belongs to the tumor necrosis factor family.
messages: Cell surface
messages: Cytokine that acts as a ligand to CD40/TNFRSF5. Costimulates T-cell proliferation and cytokine production. Involved in immunoglobulin class switching.
messages: Homotrimer.

219594:L3MBTL1
gene id: 219594:L3MBTL1
uniprot id: A0A6J3DRJ7
uniprot id: A0A6J3DVW8
uniprot id: A0A6J3DWQ4
names: Subcellular Location Annotation
messages: Nucleus

219594:LOC116499015
gene id: 219594:LOC116499015
uniprot id: A0A6J3EDS5
names: Similarity
messages: Belongs to the peptidase C1 family.

219594:SLC5A9
gene id: 219594:SLC5A9
uniprot id: A0A6J3DFW2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

219594:PTH1R
gene id: 219594:PTH1R
uniprot id: A0A6J3CP98
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 2 family.
messages: Cell membrane
messages: Membrane

219594:SAP30
gene id: 219594:SAP30
uniprot id: A0A6J3CYC2
names: Similarity
messages: Belongs to the SAP30 family.

219594:TNS1
gene id: 219594:TNS1
uniprot id: A0A6J3D2E6
uniprot id: A0A6J3D4U7
uniprot id: A0A6J3D582
uniprot id: A0A6J3D7F8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PTEN phosphatase protein family.
messages: focal adhesion

219594:LOC116501307
gene id: 219594:LOC116501307
uniprot id: A0A6J3EG59
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

219594:LOC116485995
gene id: 219594:LOC116485995
uniprot id: A0A6J3CFJ1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium channel (TC 1.A.1.10) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient.
messages: Membrane

219594:UBL3
gene id: 219594:UBL3
uniprot id: A0A6J3DBI1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

219594:ENTR1
gene id: 219594:ENTR1
uniprot id: A0A6J3DZS2
names: Similarity
messages: Belongs to the ENTR1 family.

219594:GRAMD1B
gene id: 219594:GRAMD1B
uniprot id: A0A6J3E2F1
uniprot id: A0A6J3E2G0
uniprot id: A0A6J3E3U3
uniprot id: A0A6J3E3U8
uniprot id: A0A6J3E3V3
uniprot id: A0A6J3E3V8
uniprot id: A0A6J3E6P6
uniprot id: A0A6J3E6Q7
uniprot id: A0A6J3E7F3
uniprot id: A0A6J3E7F8
uniprot id: A0A6J3E8S3
uniprot id: A0A6J3E8T4
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

219594:LOC116498317
gene id: 219594:LOC116498317
uniprot id: A0A6J3E5M2
names: Similarity
names: Subunit
messages: Belongs to the avian keratin family.
messages: The avian keratins (F-ker, S-ker, C-ker and B-ker) are a complex mixture of very similar polypeptides.

219594:ESRRB
gene id: 219594:ESRRB
uniprot id: A0A6J3D313
uniprot id: A0A6J3D3A7
uniprot id: A0A6J3D5K5
uniprot id: A0A6J3D6H0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR3 subfamily.
messages: Nucleus

219594:OBSCN
gene id: 219594:OBSCN
uniprot id: A0A6J3CML2
names: Similarity
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family.

219594:SEC24A
gene id: 219594:SEC24A
uniprot id: A0A6J3DMJ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEC23/SEC24 family. SEC24 subfamily.
messages: COPII-coated vesicle membrane
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: cytosol

219594:LOC116497345
gene id: 219594:LOC116497345
uniprot id: A0A6J3E1G5
names: Subcellular Location Annotation
messages: Membrane

219594:WEE1
gene id: 219594:WEE1
uniprot id: A0A6J3D487
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. WEE1 subfamily.
messages: Binds 2 magnesium ions per subunit.
messages: Nucleus

219594:PAX5
gene id: 219594:PAX5
uniprot id: A0A6J3EE15
uniprot id: A0A6J3EJ90
uniprot id: A0A6J3EJ95
uniprot id: A0A6J3EKT7
uniprot id: A0A6J3EKU1
names: Subcellular Location Annotation
messages: Nucleus

219594:HOXA11
gene id: 219594:HOXA11
uniprot id: A0A6J3CHF1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Abd-B homeobox family.
messages: Nucleus

219594:PAM
gene id: 219594:PAM
uniprot id: A0A6J3EC77
uniprot id: A0A6J3EDJ9
uniprot id: A0A6J3EIX8
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Binds 2 Cu(2+) ions per subunit.
messages: Binds one Zn(2+) ion per subunit.
messages: In the C-terminal section; belongs to the peptidyl-alpha-hydroxyglycine alpha-amidating lyase family.
messages: In the N-terminal section; belongs to the copper type II ascorbate-dependent monooxygenase family.
messages: Membrane
messages: secretory vesicle membrane

219594:PARK7
gene id: 219594:PARK7
uniprot id: A0A6J3E2W3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C56 family.
messages: Membrane raft

219594:LOC116487663
gene id: 219594:LOC116487663
uniprot id: A0A6J3CTK9
names: Similarity
messages: Belongs to the cytochrome P450 family.

219594:LOC116501303
gene id: 219594:LOC116501303
uniprot id: A0A6J3EMU0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

219594:PANK4
gene id: 219594:PANK4
uniprot id: A0A6J3E6W5
names: Similarity
names: Subunit
messages: Belongs to the type II pantothenate kinase family.
messages: Homodimer. Interacts with PKM.
messages: In the N-terminal section; belongs to the type II pantothenate kinase family.

219594:SLC18A1
gene id: 219594:SLC18A1
uniprot id: A0A6J3ECX4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Vesicular transporter family.
messages: Membrane

219594:VPS53
gene id: 219594:VPS53
uniprot id: A0A6J3E0Y1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VPS53 family.
messages: Endosome membrane
messages: Membrane
messages: trans-Golgi network membrane

219594:ATP6V0E1
gene id: 219594:ATP6V0E1
uniprot id: A0A6J3DQX3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the V-ATPase e1/e2 subunit family.
messages: Membrane
messages: Subunit of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment.
messages: V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex.

219594:LCK
gene id: 219594:LCK
uniprot id: A0A6J3E5A8
uniprot id: A0A6J3EAA5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.
messages: Cell membrane
messages: Membrane
messages: cytosol

219594:CNIH1
gene id: 219594:CNIH1
uniprot id: A0A6J3D2H2
uniprot id: A0A6J3D2P2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cornichon family.
messages: Membrane

219594:ATP1B4
gene id: 219594:ATP1B4
uniprot id: A0A6J3DNQ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the X(+)/potassium ATPases subunit beta family.
messages: Membrane
messages: This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane.

219594:UCHL3
gene id: 219594:UCHL3
uniprot id: A0A6J3CJQ9
uniprot id: A0A6J3CJS3
uniprot id: A0A6J3CPE2
names: Similarity
messages: Belongs to the peptidase C12 family.

219594:PDK2
gene id: 219594:PDK2
uniprot id: A0A6J3E4L4
uniprot id: A0A6J3E8Z7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PDK/BCKDK protein kinase family.
messages: Mitochondrion matrix

219594:ACAD8
gene id: 219594:ACAD8
uniprot id: A0A6J3E8N9
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

219594:ATP6V0A4
gene id: 219594:ATP6V0A4
uniprot id: A0A6J3EHZ4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the V-ATPase 116 kDa subunit family.
messages: Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.
messages: Membrane

219594:PGR
gene id: 219594:PGR
uniprot id: A0A6J3DVB1
uniprot id: A0A6J3DVC2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Composed of three domains: a modulating N-terminal domain, a DNA-binding domain and a C-terminal ligand-binding domain.
messages: Cytoplasm
messages: Nucleus
messages: Steroid hormone receptor involved in the regulation of eukaryotic gene expression which affects cellular proliferation and differentiation in target tissues.

219594:FAM126B
gene id: 219594:FAM126B
uniprot id: A0A6J3D5U9
uniprot id: A0A6J3D8V4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Hyccin family.
messages: Cell membrane
messages: Membrane
messages: cytosol

219594:HTR4
gene id: 219594:HTR4
uniprot id: A0A6J3DQ49
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Endosome
messages: Membrane
messages: This is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that stimulate adenylate cyclase.

219594:KDM4C
gene id: 219594:KDM4C
uniprot id: A0A6J3EEF6
uniprot id: A0A6J3EJL3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the JHDM3 histone demethylase family.
messages: Nucleus

219594:CRHBP
gene id: 219594:CRHBP
uniprot id: A0A6J3EK34
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CRF-binding protein family.
messages: Binds CRF and inactivates it. May prevent inappropriate pituitary-adrenal stimulation in pregnancy.
messages: Secreted

219594:SMAD6
gene id: 219594:SMAD6
uniprot id: A0A6J3DI93
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dwarfin/SMAD family.
messages: Cytoplasm
messages: Nucleus

219594:RSPH3
gene id: 219594:RSPH3
uniprot id: A0A6J3CSR1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the flagellar radial spoke RSP3 family.
messages: flagellum axoneme

219594:B3GALT1
gene id: 219594:B3GALT1
uniprot id: A0A6J3DA51
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane

219594:MAB21L2
gene id: 219594:MAB21L2
uniprot id: A0A6J3D255
names: Similarity
messages: Belongs to the mab-21 family.

219594:RAB3GAP1
gene id: 219594:RAB3GAP1
uniprot id: A0A6J3D575
uniprot id: A0A6J3DB45
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Rab3-GAP catalytic subunit family.
messages: Cytoplasm
messages: Endoplasmic reticulum

219594:SLC35B4
gene id: 219594:SLC35B4
uniprot id: A0A6J3EJN6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleotide-sugar transporter family. SLC35B subfamily.
messages: Membrane

219594:TBCE
gene id: 219594:TBCE
uniprot id: A0A6J3CRZ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TBCE family.
messages: Cytoplasm

219594:NUP133
gene id: 219594:NUP133
uniprot id: A0A6J3CPV9
uniprot id: A0A6J3CVZ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleoporin Nup133 family.
messages: nuclear pore complex

219594:NKX6-3
gene id: 219594:NKX6-3
uniprot id: A0A6J3ED50
names: Subcellular Location Annotation
messages: Nucleus

219594:IRX4
gene id: 219594:IRX4
uniprot id: A0A6J3CFP5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TALE/IRO homeobox family.
messages: Nucleus

219594:CMPK2
gene id: 219594:CMPK2
uniprot id: A0A6J3CQI6
names: Similarity
messages: Belongs to the thymidylate kinase family.

219594:AZIN2
gene id: 219594:AZIN2
uniprot id: A0A6J3EAC0
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family.

219594:RPAP1
gene id: 219594:RPAP1
uniprot id: A0A6J3D0W1
uniprot id: A0A6J3D3J0
names: Similarity
messages: Belongs to the RPAP1 family.

219594:ATP7A
gene id: 219594:ATP7A
uniprot id: A0A6J3DKI5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Membrane
messages: trans-Golgi network membrane

219594:LOC116500606
gene id: 219594:LOC116500606
uniprot id: A0A6J3ED20
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

219594:P4HA1
gene id: 219594:P4HA1
uniprot id: A0A6J3D5J2
uniprot id: A0A6J3D888
uniprot id: A0A6J3DAY2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P4HA family.
messages: Catalyzes the post-translational formation of 4-hydroxyproline in -Xaa-Pro-Gly- sequences in collagens and other proteins.
messages: Endoplasmic reticulum lumen

219594:SPEG
gene id: 219594:SPEG
uniprot id: A0A6J3DA57
names: Similarity
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family.

219594:LOC116499317
gene id: 219594:LOC116499317
uniprot id: A0A6J3E882
names: Cofactor
names: Similarity
messages: Belongs to the 5'(3')-deoxyribonucleotidase family.
messages: Binds 1 Mg(2+) ion per subunit.

219594:CADM2
gene id: 219594:CADM2
uniprot id: A0A6J3EQ92
uniprot id: A0A6J3ERQ5
names: Similarity
messages: Belongs to the nectin family.

219594:LOC116485690
gene id: 219594:LOC116485690
uniprot id: A0A6J3CJS7
names: Similarity
names: Subunit
messages: Belongs to the avian keratin family.
messages: The avian keratins (F-ker, S-ker, C-ker and B-ker) are a complex mixture of very similar polypeptides.

219594:LOC116498656
gene id: 219594:LOC116498656
uniprot id: A0A6J3EC05
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IL-10 family.
messages: Immune regulatory cytokine.
messages: Secreted

219594:USP35
gene id: 219594:USP35
uniprot id: A0A6J3EH71
names: Similarity
messages: Belongs to the peptidase C19 family.

219594:TAAR5
gene id: 219594:TAAR5
uniprot id: A0A6J3CTX9
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

219594:P3H3
gene id: 219594:P3H3
uniprot id: A0A6J3EQ65
names: Similarity
messages: Belongs to the leprecan family.

219594:LOC116490909
gene id: 219594:LOC116490909
uniprot id: A0A6J3D7J8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UDP-glycosyltransferase family.
messages: Membrane

219594:LOC116500476
gene id: 219594:LOC116500476
uniprot id: A0A6J3EHK9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

219594:TMEM244
gene id: 219594:TMEM244
uniprot id: A0A6J3CQH3
names: Subcellular Location Annotation
messages: Membrane

219594:SETD1B
gene id: 219594:SETD1B
uniprot id: A0A6J3DUM5
names: Subcellular Location Annotation
messages: Chromosome
messages: Nucleus speckle

219594:OLFM3
gene id: 219594:OLFM3
uniprot id: A0A6J3D9X2
uniprot id: A0A6J3DDJ0
uniprot id: A0A6J3DFP4
names: Subcellular Location Annotation
messages: Secreted
messages: Synapse

219594:UNC45B
gene id: 219594:UNC45B
uniprot id: A0A6J3E1I5
names: Subcellular Location Annotation
messages: A band
messages: Z line
messages: perinuclear region

219594:HOXD4
gene id: 219594:HOXD4
uniprot id: A0A6J3D4U1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Antp homeobox family.
messages: Nucleus

219594:NUP205
gene id: 219594:NUP205
uniprot id: A0A6J3DJ68
uniprot id: A0A6J3DKR4
names: Similarity
messages: Belongs to the NUP186/NUP192/NUP205 family.

219594:ACSS2
gene id: 219594:ACSS2
uniprot id: A0A6J3DSZ0
uniprot id: A0A6J3DX65
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

219594:C17H12orf43
gene id: 219594:C17H12orf43
uniprot id: A0A6J3DYJ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CUSTOS family.
messages: Nucleus envelope

219594:BZW1
gene id: 219594:BZW1
uniprot id: A0A6J3D547
uniprot id: A0A6J3D7B7
names: Similarity
messages: Belongs to the BZW family.

219594:PBX3
gene id: 219594:PBX3
uniprot id: A0A6J3DX15
uniprot id: A0A6J3DYU4
uniprot id: A0A6J3E357
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TALE/PBX homeobox family.
messages: Nucleus

219594:LOC116495988
gene id: 219594:LOC116495988
uniprot id: A0A6J3DYC6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Deltex family.
messages: Cytoplasm

219594:CACYBP
gene id: 219594:CACYBP
uniprot id: A0A6J3DFB6
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: May be involved in calcium-dependent ubiquitination and subsequent proteasomal degradation of target proteins. Probably serves as a molecular bridge in ubiquitin E3 complexes. Participates in the ubiquitin-mediated degradation of beta-catenin (CTNNB1).
messages: Nucleus

219594:SYN3
gene id: 219594:SYN3
uniprot id: A0A6J3EQ32
names: Similarity
messages: Belongs to the synapsin family.

219594:ATE1
gene id: 219594:ATE1
uniprot id: A0A6J3D6D2
uniprot id: A0A6J3D933
uniprot id: A0A6J3DBU6
uniprot id: A0A6J3DCA9
names: Function
names: Similarity
messages: Belongs to the R-transferase family.
messages: Involved in the post-translational conjugation of arginine to the N-terminal aspartate or glutamate of a protein. This arginylation is required for degradation of the protein via the ubiquitin pathway.

219594:LOC116498123
gene id: 219594:LOC116498123
uniprot id: A0A6J3E3P9
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CCN family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

219594:SETD7
gene id: 219594:SETD7
uniprot id: A0A6J3CXE3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. SET7 subfamily.
messages: Chromosome
messages: Histone methyltransferase that specifically monomethylates 'Lys-4' of histone H3. H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation. Plays a central role in the transcriptional activation of genes.
messages: Nucleus

219594:PTH
gene id: 219594:PTH
uniprot id: A0A6J3D2B2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the parathyroid hormone family.
messages: PTH elevates calcium level by dissolving the salts in bone and preventing their renal excretion.
messages: Secreted

219594:TBX2
gene id: 219594:TBX2
uniprot id: A0A6J3E128
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

219594:EIF5B
gene id: 219594:EIF5B
uniprot id: A0A6J3D0N4
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.

219594:GALNS
gene id: 219594:GALNS
uniprot id: A0A6J3DNF6
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sulfatase family.
messages: Binds 1 Ca(2+) ion per subunit.
messages: Homodimer.
messages: Lysosome

219594:ARR3
gene id: 219594:ARR3
uniprot id: A0A6J3DLK4
names: Similarity
messages: Belongs to the arrestin family.

219594:TRAF5
gene id: 219594:TRAF5
uniprot id: A0A6J3CTN2
uniprot id: A0A6J3CVX1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TNF receptor-associated factor family.
messages: Cytoplasm

219594:ADAM15
gene id: 219594:ADAM15
uniprot id: A0A6J3EE46
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:ESR2
gene id: 219594:ESR2
uniprot id: A0A6J3D3G4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR3 subfamily.
messages: Nucleus

219594:SLC4A2
gene id: 219594:SLC4A2
uniprot id: A0A6J3CJN2
uniprot id: A0A6J3CKV5
uniprot id: A0A6J3CP96
names: Similarity
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Belongs to the anion exchanger (TC 2.A.31) family.
messages: Cell membrane
messages: Membrane

219594:LOC116495431
gene id: 219594:LOC116495431
uniprot id: A0A6J3DSX7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tubulin family.
messages: cytoskeleton

219594:SPARCL1
gene id: 219594:SPARCL1
uniprot id: A0A6J3D008
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPARC family.
messages: Secreted

219594:NDRG4
gene id: 219594:NDRG4
uniprot id: A0A6J3DL36
uniprot id: A0A6J3DL40
uniprot id: A0A6J3DMN9
uniprot id: A0A6J3DMP4
names: Similarity
messages: Belongs to the NDRG family.

219594:DCP2
gene id: 219594:DCP2
uniprot id: A0A6J3ECV6
uniprot id: A0A6J3EE90
names: Similarity
messages: Belongs to the Nudix hydrolase family. DCP2 subfamily.

219594:TSEN15
gene id: 219594:TSEN15
uniprot id: A0A6J3DFD4
names: Similarity
messages: Belongs to the SEN15 family.

219594:SLC39A12
gene id: 219594:SLC39A12
uniprot id: A0A6J3CG18
uniprot id: A0A6J3CIP2
uniprot id: A0A6J3CKL4
uniprot id: A0A6J3CMA9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZIP transporter (TC 2.A.5) family.
messages: Membrane

219594:RPS24
gene id: 219594:RPS24
uniprot id: A0A6J3DA45
uniprot id: A0A6J3DAU7
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS24 family.

219594:ARL6IP4
gene id: 219594:ARL6IP4
uniprot id: A0A6J3DWN0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ARL6IP4 family.
messages: Nucleus speckle
messages: nucleolus

219594:ADRA2C
gene id: 219594:ADRA2C
uniprot id: A0A6J3CZ51
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

219594:LOC116500145
gene id: 219594:LOC116500145
uniprot id: A0A6J3EFZ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

219594:TRAPPC3L
gene id: 219594:TRAPPC3L
uniprot id: A0A6J3CSD5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAPP small subunits family. BET3 subfamily.
messages: Endoplasmic reticulum
messages: Homodimer.
messages: May play a role in vesicular transport from endoplasmic reticulum to Golgi.
messages: cis-Golgi network

219594:LGR5
gene id: 219594:LGR5
uniprot id: A0A6J3EJ06
uniprot id: A0A6J3EMV8
names: Subcellular Location Annotation
messages: Membrane

219594:TDRD9
gene id: 219594:TDRD9
uniprot id: A0A6J3D6Q6
names: Similarity
messages: Belongs to the DEAD box helicase family. DEAH subfamily.

219594:ABITRAM
gene id: 219594:ABITRAM
uniprot id: A0A6J3CJ26
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABITRAM family.
messages: growth cone
messages: lamellipodium

219594:FGA
gene id: 219594:FGA
uniprot id: A0A6J3CYL2
names: Subcellular Location Annotation
names: Subunit
messages: Heterohexamer; disulfide linked. Contains 2 sets of 3 non-identical chains (alpha, beta and gamma). The 2 heterotrimers are in head to head conformation with the N-termini in a small central domain.
messages: Secreted

219594:NOX5
gene id: 219594:NOX5
uniprot id: A0A6J3DKS6
names: Subcellular Location Annotation
messages: Membrane

219594:HNF1A
gene id: 219594:HNF1A
uniprot id: A0A6J3DVR7
uniprot id: A0A6J3DZT8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HNF1 homeobox family.
messages: Nucleus

219594:CSMD2
gene id: 219594:CSMD2
uniprot id: A0A6J3E805
uniprot id: A0A6J3E9E9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:FMNL3
gene id: 219594:FMNL3
uniprot id: A0A6J3EBZ1
uniprot id: A0A6J3EFC3
names: Similarity
messages: Belongs to the formin homology family.

219594:LOC116487630
gene id: 219594:LOC116487630
uniprot id: A0A6J3CNJ3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.
messages: cytoskeleton

219594:LOC116487511
gene id: 219594:LOC116487511
uniprot id: A0A6J3CSX4
names: Caution
names: Cofactor
names: Subcellular Location Annotation
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

219594:LOC116485688
gene id: 219594:LOC116485688
uniprot id: A0A6J3CG75
names: Similarity
names: Subunit
messages: Belongs to the avian keratin family.
messages: The avian keratins (F-ker, S-ker, C-ker and B-ker) are a complex mixture of very similar polypeptides.

219594:SLC1A7
gene id: 219594:SLC1A7
uniprot id: A0A6J3DCM5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Membrane

219594:AP2M1
gene id: 219594:AP2M1
uniprot id: A0A6J3DBW2
uniprot id: A0A6J3DEI0
uniprot id: A0A6J3DFN9
uniprot id: A0A6J3DFP5
uniprot id: A0A6J3DHD8
uniprot id: A0A6J3DHY4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adaptor complexes medium subunit family.
messages: Cell membrane
messages: coated pit

219594:NR4A3
gene id: 219594:NR4A3
uniprot id: A0A6J3CJJ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

219594:SLC44A5
gene id: 219594:SLC44A5
uniprot id: A0A6J3DFL0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CTL (choline transporter-like) family.
messages: Cell membrane
messages: Choline transporter.
messages: Membrane

219594:FBLN2
gene id: 219594:FBLN2
uniprot id: A0A6J3DER5
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fibulin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

219594:E2F3
gene id: 219594:E2F3
uniprot id: A0A6J3CJ27
uniprot id: A0A6J3CKI5
uniprot id: A0A6J3CLQ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the E2F/DP family.
messages: Nucleus

219594:MDGA1
gene id: 219594:MDGA1
uniprot id: A0A6J3CPA5
uniprot id: A0A6J3CRJ9
uniprot id: A0A6J3CSK6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

219594:SMIM15
gene id: 219594:SMIM15
uniprot id: A0A6J3ED74
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SMIM15 family.
messages: Membrane

219594:DIPK1B
gene id: 219594:DIPK1B
uniprot id: A0A6J3DZL6
names: Similarity
messages: Belongs to the DIPK family.

219594:POT1
gene id: 219594:POT1
uniprot id: A0A6J3ECA1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the telombin family.
messages: Nucleus
messages: telomere

219594:AMER3
gene id: 219594:AMER3
uniprot id: A0A6J3DIJ9
names: Similarity
messages: Belongs to the Amer family.

219594:LOC116498553
gene id: 219594:LOC116498553
uniprot id: A0A6J3EA55
names: Similarity
names: Subunit
messages: Belongs to the avian keratin family.
messages: The avian keratins (F-ker, S-ker, C-ker and B-ker) are a complex mixture of very similar polypeptides.

219594:NPBWR1
gene id: 219594:NPBWR1
uniprot id: A0A6J3CLQ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

219594:ITGB5
gene id: 219594:ITGB5
uniprot id: A0A6J3D9M9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin beta chain family.
messages: Cell membrane
messages: Membrane

219594:KCNJ15
gene id: 219594:KCNJ15
uniprot id: A0A6J3E2B8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family.
messages: Membrane

219594:LLGL1
gene id: 219594:LLGL1
uniprot id: A0A6J3DQT4
uniprot id: A0A6J3DV65
uniprot id: A0A6J3DW19
names: Similarity
messages: Belongs to the WD repeat L(2)GL family.

219594:LYRM7
gene id: 219594:LYRM7
uniprot id: A0A6J3EDK0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Assembly factor required for Rieske Fe-S protein UQCRFS1 incorporation into the cytochrome b-c1 (CIII) complex. Functions as a chaperone, binding to this subunit within the mitochondrial matrix and stabilizing it prior to its translocation and insertion into the late CIII dimeric intermediate within the mitochondrial inner membrane.
messages: Belongs to the complex I LYR family.
messages: Interacts with UQCRFS1.
messages: Mitochondrion matrix

219594:ZNF330
gene id: 219594:ZNF330
uniprot id: A0A6J3D1J7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NOA36 family.
messages: nucleolus

219594:LOC116500647
gene id: 219594:LOC116500647
uniprot id: A0A6J3EK70
names: Subcellular Location Annotation
messages: Chromosome

219594:LDAH
gene id: 219594:LDAH
uniprot id: A0A6J3CLM8
uniprot id: A0A6J3CRK4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AB hydrolase superfamily. LDAH family.
messages: Lipid droplet

219594:HBP1
gene id: 219594:HBP1
uniprot id: A0A6J3DG18
names: Function
names: Subcellular Location Annotation
messages: Nucleus
messages: Transcriptional repressor that binds to the promoter region of target genes. Plays a role in the regulation of the cell cycle and of the Wnt pathway. Binds preferentially to the sequence 5'-TTCATTCATTCA-3'. Binding to the histone H1.0 promoter is enhanced by interaction with RB1. Disrupts the interaction between DNA and TCF4.

219594:CNKSR3
gene id: 219594:CNKSR3
uniprot id: A0A6J3CR63
uniprot id: A0A6J3CS70
names: Similarity
messages: Belongs to the CNKSR family.

219594:LOC116499755
gene id: 219594:LOC116499755
uniprot id: A0A6J3E9V7
names: Similarity
names: Subunit
messages: Belongs to the avian keratin family.
messages: The avian keratins (F-ker, S-ker, C-ker and B-ker) are a complex mixture of very similar polypeptides.

219594:LYVE1
gene id: 219594:LYVE1
uniprot id: A0A6J3D3N9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:LOC116494478
gene id: 219594:LOC116494478
uniprot id: A0A6J3DNR4
names: Similarity
messages: Belongs to the PrpD family.

219594:GPRC5B
gene id: 219594:GPRC5B
uniprot id: A0A6J3DPI7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

219594:TAF4B
gene id: 219594:TAF4B
uniprot id: A0A6J3CF25
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAF4 family.
messages: Nucleus

219594:ATP13A5
gene id: 219594:ATP13A5
uniprot id: A0A6J3DCL0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily.
messages: Membrane

219594:STX16
gene id: 219594:STX16
uniprot id: A0A6J3DTP2
uniprot id: A0A6J3DWN8
uniprot id: A0A6J3DXN0
names: Similarity
messages: Belongs to the syntaxin family.

219594:LRRFIP2
gene id: 219594:LRRFIP2
uniprot id: A0A6J3CEJ1
uniprot id: A0A6J3CEJ6
uniprot id: A0A6J3CG69
uniprot id: A0A6J3CH51
uniprot id: A0A6J3CH56
uniprot id: A0A6J3CJ36
uniprot id: A0A6J3CKT0
uniprot id: A0A6J3CKT9
names: Similarity
messages: Belongs to the LRRFIP family.

219594:SLC35B3
gene id: 219594:SLC35B3
uniprot id: A0A6J3CE69
uniprot id: A0A6J3CF67
uniprot id: A0A6J3CH15
uniprot id: A0A6J3CIT7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleotide-sugar transporter family. SLC35B subfamily.
messages: Membrane

219594:SNRPC
gene id: 219594:SNRPC
uniprot id: A0A6J3E811
uniprot id: A0A6J3ED59
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the U1 small nuclear ribonucleoprotein C family.
messages: Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. SNRPC/U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing. The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA. Stimulates commitment or early (E) complex formation by stabilizing the base pairing of the 5' end of the U1 snRNA and the 5' splice-site region.
messages: Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. snrpc/U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing. The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA. Stimulates E complex formation by stabilizing the base pairing of the 5' end of the U1 snRNA and the 5' splice-site region.
messages: Nucleus
messages: U1 snRNP is composed of the 7 core Sm proteins SNRPB, SNRPD1, SNRPD2, SNRPD3, SNRPE, SNRPF and SNRPG that assemble in a heptameric protein ring on the Sm site of the small nuclear RNA to form the core snRNP, and at least 3 U1 snRNP-specific proteins SNRNP70/U1-70K, SNRPA/U1-A and SNRPC/U1-C. SNRPC/U1-C interacts with U1 snRNA and the 5' splice-site region of the pre-mRNA.

219594:MLF2
gene id: 219594:MLF2
uniprot id: A0A6J3EM22
uniprot id: A0A6J3EM33
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MLF family.
messages: Cytoplasm

219594:ITPRIPL2
gene id: 219594:ITPRIPL2
uniprot id: A0A6J3DQA4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ITPRIP family.
messages: Membrane

219594:CD3E
gene id: 219594:CD3E
uniprot id: A0A6J3E2Q7
names: Subcellular Location Annotation
messages: Membrane

219594:RIOX2
gene id: 219594:RIOX2
uniprot id: A0A6J3CCE2
uniprot id: A0A6J3CCG2
uniprot id: A0A6J3CF40
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ROX family.
messages: Belongs to the ROX family. MINA53 subfamily.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Nucleus
messages: Oxygenase that can act as both a histone lysine demethylase and a ribosomal histidine hydroxylase.

219594:PCNP
gene id: 219594:PCNP
uniprot id: A0A6J3DBG1
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Interacts with UHRF2/NIRF.
messages: May be involved in cell cycle regulation.
messages: Nucleus

219594:GABRB1
gene id: 219594:GABRB1
uniprot id: A0A6J3CWG0
uniprot id: A0A6J3CWU6
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

219594:HPSE
gene id: 219594:HPSE
uniprot id: A0A6J3D150
names: Similarity
messages: Belongs to the glycosyl hydrolase 79 family.

219594:COG3
gene id: 219594:COG3
uniprot id: A0A6J3DV88
names: Function
names: Similarity
messages: Belongs to the COG3 family.
messages: Involved in ER-Golgi transport.

219594:LOC116501317
gene id: 219594:LOC116501317
uniprot id: A0A6J3ELI3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

219594:DUS3L
gene id: 219594:DUS3L
uniprot id: A0A6J3E7V4
uniprot id: A0A6J3E9E3
uniprot id: A0A6J3ECI0
names: Similarity
messages: Belongs to the dus family. Dus3 subfamily.

219594:RBBP4
gene id: 219594:RBBP4
uniprot id: A0A6J3E9Y5
names: Subcellular Location Annotation
messages: Nucleus

219594:PIM1
gene id: 219594:PIM1
uniprot id: A0A6J3EAJ7
names: Function
names: Similarity
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. PIM subfamily.
messages: Proto-oncogene with serine/threonine kinase activity involved in cell survival and cell proliferation.

219594:LOC116486261
gene id: 219594:LOC116486261
uniprot id: A0A6J3CIF4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

219594:TUT7
gene id: 219594:TUT7
uniprot id: A0A6J3ED45
uniprot id: A0A6J3EEG6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-B-like family.
messages: Cytoplasm

219594:LOC116489506
gene id: 219594:LOC116489506
uniprot id: A0A6J3D027
names: Subcellular Location Annotation
messages: Membrane

219594:LOC116489327
gene id: 219594:LOC116489327
uniprot id: A0A6J3CZ76
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.

219594:PSMC2
gene id: 219594:PSMC2
uniprot id: A0A6J3EK08
names: Similarity
messages: Belongs to the AAA ATPase family.

219594:FANCC
gene id: 219594:FANCC
uniprot id: A0A6J3EJ24
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the multisubunit FA complex composed of FANCA, FANCB, FANCC, FANCE, FANCF, FANCG, FANCL/PHF9 and FANCM. This complex may also include HSP70.
messages: DNA repair protein that may operate in a postreplication repair or a cell cycle checkpoint function. May be implicated in interstrand DNA cross-link repair and in the maintenance of normal chromosome stability. Upon IFNG induction, may facilitate STAT1 activation by recruiting STAT1 to IFNGR1.
messages: Nucleus

219594:LIN9
gene id: 219594:LIN9
uniprot id: A0A6J3CTP6
uniprot id: A0A6J3CWE9
names: Similarity
messages: Belongs to the lin-9 family.

219594:WASHC1
gene id: 219594:WASHC1
uniprot id: A0A6J3ENW4
uniprot id: A0A6J3ENW9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WASH1 family.
messages: Early endosome membrane
messages: Endosome membrane
messages: Recycling endosome membrane

219594:MNS1
gene id: 219594:MNS1
uniprot id: A0A6J3DJW2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MNS1 family.
messages: Nucleus
messages: cilium axoneme
messages: flagellum axoneme

219594:CPOX
gene id: 219594:CPOX
uniprot id: A0A6J3EIW3
names: Similarity
names: Subunit
messages: Belongs to the aerobic coproporphyrinogen-III oxidase family.
messages: Homodimer.

219594:YTHDF2
gene id: 219594:YTHDF2
uniprot id: A0A6J3E819
names: Function
names: Similarity
messages: Belongs to the YTHDF family.
messages: Specifically recognizes and binds N6-methyladenosine (m6A)-containing RNAs, and regulates mRNA stability. M6A is a modification present at internal sites of mRNAs and some non-coding RNAs and plays a role in mRNA stability and processing.

219594:SCAMP1
gene id: 219594:SCAMP1
uniprot id: A0A6J3EGD8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SCAMP family.
messages: Membrane

219594:SH3PXD2A
gene id: 219594:SH3PXD2A
uniprot id: A0A6J3D5Z7
uniprot id: A0A6J3D973
uniprot id: A0A6J3DBV9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SH3PXD2 family.
messages: Cytoplasm

219594:LONP1
gene id: 219594:LONP1
uniprot id: A0A6J3EE34
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of misfolded, unassembled or oxidatively damaged polypeptides as well as certain short-lived regulatory proteins in the mitochondrial matrix. May also have a chaperone function in the assembly of inner membrane protein complexes. Participates in the regulation of mitochondrial gene expression and in the maintenance of the integrity of the mitochondrial genome. Binds to mitochondrial DNA in a site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: Homohexamer or homoheptamer. Organized in a ring with a central cavity.
messages: Mitochondrion matrix
messages: Nucleus

219594:LOC116498817
gene id: 219594:LOC116498817
uniprot id: A0A6J3E647
names: Similarity
messages: Belongs to the peptidase A1 family.

219594:LOC116501457
gene id: 219594:LOC116501457
uniprot id: A0A6J3ENF3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GOLPH3/VPS74 family.
messages: Golgi stack membrane
messages: Membrane
messages: trans-Golgi network membrane

219594:PRPS2
gene id: 219594:PRPS2
uniprot id: A0A6J3E0Z5
uniprot id: A0A6J3E3N5
uniprot id: A0A6J3E4J4
uniprot id: A0A6J3E4K5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family.
messages: Catalyzes the synthesis of phosphoribosylpyrophosphate (PRPP) that is essential for nucleotide synthesis.
messages: Homodimer. The active form is probably a hexamer composed of 3 homodimers.

219594:LOC116490060
gene id: 219594:LOC116490060
uniprot id: A0A6J3D0P9
names: Similarity
messages: Belongs to the protease inhibitor I39 (alpha-2-macroglobulin) family.

219594:TPH1
gene id: 219594:TPH1
uniprot id: A0A6J3D2W3
names: Similarity
messages: Belongs to the biopterin-dependent aromatic amino acid hydroxylase family.

219594:SVIL
gene id: 219594:SVIL
uniprot id: A0A6J3CGJ9
uniprot id: A0A6J3CI50
uniprot id: A0A6J3CI55
uniprot id: A0A6J3CJA0
uniprot id: A0A6J3CJA6
uniprot id: A0A6J3CL40
uniprot id: A0A6J3CL46
uniprot id: A0A6J3CMR9
uniprot id: A0A6J3CMS4
names: Similarity
messages: Belongs to the villin/gelsolin family.

219594:ZDHHC23
gene id: 219594:ZDHHC23
uniprot id: A0A6J3ENG6
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

219594:FRZB
gene id: 219594:FRZB
uniprot id: A0A6J3D7N6
names: Caution
names: Function
names: Similarity
messages: Belongs to the secreted frizzled-related protein (sFRP) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Soluble frizzled-related proteins (sFRPS) function as modulators of Wnt signaling through direct interaction with Wnts. They have a role in regulating cell growth and differentiation in specific cell types. SFRP3/FRZB appears to be involved in limb skeletogenesis. Antagonist of Wnt8 signaling. Regulates chondrocyte maturation and long bone development.

219594:CPLX1
gene id: 219594:CPLX1
uniprot id: A0A6J3EC82
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complexin/synaphin family.
messages: Synapse

219594:TSPAN7
gene id: 219594:TSPAN7
uniprot id: A0A6J3D720
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

219594:LOC116486521
gene id: 219594:LOC116486521
uniprot id: A0A6J3CJQ7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transthyretin family.
messages: Homotetramer.
messages: Secreted
messages: Thyroid hormone-binding protein. Probably transports thyroxine from the bloodstream to the brain.

219594:SERBP1
gene id: 219594:SERBP1
uniprot id: A0A6J3DC00
uniprot id: A0A6J3DF59
names: Similarity
messages: Belongs to the SERBP1-HABP4 family.

219594:CNN3
gene id: 219594:CNN3
uniprot id: A0A6J3DFG0
names: Function
names: Similarity
messages: Belongs to the calponin family.
messages: Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity.

219594:ERGIC2
gene id: 219594:ERGIC2
uniprot id: A0A6J3DAS4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ERGIC family.
messages: Endoplasmic reticulum membrane
messages: Endoplasmic reticulum-Golgi intermediate compartment membrane
messages: Golgi apparatus membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays a role in transport between endoplasmic reticulum and Golgi.

219594:FOXN3
gene id: 219594:FOXN3
uniprot id: A0A6J3D013
uniprot id: A0A6J3D2F2
uniprot id: A0A6J3D2L2
uniprot id: A0A6J3D4X7
uniprot id: A0A6J3D5W4
names: Function
names: Subcellular Location Annotation
messages: Acts as a transcriptional repressor. May be involved in DNA damage-inducible cell cycle arrests (checkpoints).
messages: Nucleus

219594:LOC116491460
gene id: 219594:LOC116491460
uniprot id: A0A6J3DDA8
names: Similarity
messages: Belongs to the cytochrome P450 family.

219594:TMTC1
gene id: 219594:TMTC1
uniprot id: A0A6J3DDP1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMTC family.
messages: Endoplasmic reticulum
messages: Membrane

219594:LOC116485369
gene id: 219594:LOC116485369
uniprot id: A0A6J3CID5
names: Similarity
messages: Belongs to the serpin family.

219594:TMEM132C
gene id: 219594:TMEM132C
uniprot id: A0A6J3DVW5
uniprot id: A0A6J3DYW7
uniprot id: A0A6J3DZY6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM132 family.
messages: Membrane

219594:WARS2
gene id: 219594:WARS2
uniprot id: A0A6J3EFL0
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

219594:LOC116490529
gene id: 219594:LOC116490529
uniprot id: A0A6J3D5E0
uniprot id: A0A6J3D7Y3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium channel (TC 1.A.1.10) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient.
messages: Membrane

219594:LOC116491168
gene id: 219594:LOC116491168
uniprot id: A0A6J3DC09
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

219594:DGKA
gene id: 219594:DGKA
uniprot id: A0A6J3EBT3
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic diacylglycerol kinase family.
messages: Monomer.

219594:FAM199X
gene id: 219594:FAM199X
uniprot id: A0A6J3DT22
names: Similarity
messages: Belongs to the FAM199 family.

219594:C22H11orf1
gene id: 219594:C22H11orf1
uniprot id: A0A6J3E2Q9
names: Function
messages: Microtubule inner protein (MIP) part of the dynein-decorated doublet microtubules (DMTs) in cilia axoneme, which is required for motile cilia beating.

219594:CCN2
gene id: 219594:CCN2
uniprot id: A0A6J3CTG6
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CCN family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

219594:TPR
gene id: 219594:TPR
uniprot id: A0A6J3DDV7
uniprot id: A0A6J3DEZ6
uniprot id: A0A6J3DH79
names: Similarity
messages: Belongs to the TPR family.

219594:LOC116501471
gene id: 219594:LOC116501471
uniprot id: A0A6J3EGT9
uniprot id: A0A6J3EGU4
uniprot id: A0A6J3EGU8
uniprot id: A0A6J3EIC4
uniprot id: A0A6J3EID0
uniprot id: A0A6J3EM38
uniprot id: A0A6J3EM50
uniprot id: A0A6J3EM53
uniprot id: A0A6J3ENH7
uniprot id: A0A6J3ENI2
names: Similarity
messages: Belongs to the dymeclin family.

219594:LOC116489820
gene id: 219594:LOC116489820
uniprot id: A0A6J3D1W1
names: Similarity
messages: Belongs to the glycine N-acyltransferase family.

219594:NPRL2
gene id: 219594:NPRL2
uniprot id: A0A6J3DIP0
names: Similarity
messages: Belongs to the NPR2 family.

219594:PRPSAP2
gene id: 219594:PRPSAP2
uniprot id: A0A6J3DST5
names: Similarity
messages: Belongs to the ribose-phosphate pyrophosphokinase family.

219594:LOC116495403
gene id: 219594:LOC116495403
uniprot id: C7EK60
names: Similarity
messages: Belongs to the globin family.

219594:FAM214A
gene id: 219594:FAM214A
uniprot id: A0A6J3DG85
uniprot id: A0A6J3DLT1
uniprot id: A0A6J3DM99
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATOS family.
messages: Nucleus

219594:ACAA1
gene id: 219594:ACAA1
uniprot id: A0A6J3CGW3
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

219594:EMC2
gene id: 219594:EMC2
uniprot id: A0A6J3CIA0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EMC2 family.
messages: Component of the ER membrane protein complex (EMC).
messages: Endoplasmic reticulum membrane
messages: Part of the endoplasmic reticulum membrane protein complex (EMC) that enables the energy-independent insertion into endoplasmic reticulum membranes of newly synthesized membrane proteins.

219594:KAT6B
gene id: 219594:KAT6B
uniprot id: A0A6J3D712
uniprot id: A0A6J3D9Q6
uniprot id: A0A6J3DCK0
names: Similarity
messages: Belongs to the MYST (SAS/MOZ) family.

219594:OGDH
gene id: 219594:OGDH
uniprot id: A0A6J3EDI7
names: Similarity
messages: Belongs to the alpha-ketoglutarate dehydrogenase family.

219594:LOC116501448
gene id: 219594:LOC116501448
uniprot id: A0A6J3EM11
names: Similarity
messages: Belongs to the GSKIP family.

219594:KCNK2
gene id: 219594:KCNK2
uniprot id: A0A6J3CTC8
uniprot id: A0A6J3CTU1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
messages: Membrane

219594:SGTB
gene id: 219594:SGTB
uniprot id: A0A6J3EGB8
uniprot id: A0A6J3EJZ2
names: Similarity
messages: Belongs to the SGT family.

219594:GABRG1
gene id: 219594:GABRG1
uniprot id: A0A6J3CTJ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

219594:DLGAP5
gene id: 219594:DLGAP5
uniprot id: A0A6J3D1S5
uniprot id: A0A6J3D6R7
names: Similarity
messages: Belongs to the SAPAP family.

219594:CPNE3
gene id: 219594:CPNE3
uniprot id: A0A6J3CE41
names: Similarity
messages: Belongs to the copine family.

219594:TLR5
gene id: 219594:TLR5
uniprot id: A0A6J3CMY1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Toll-like receptor family.
messages: Membrane

219594:TM6SF2
gene id: 219594:TM6SF2
uniprot id: A0A6J3ECM0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TM6SF family.
messages: Membrane

219594:GJB1
gene id: 219594:GJB1
uniprot id: A0A6J3DRG3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family. Beta-type (group I) subfamily.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

219594:HSPA9
gene id: 219594:HSPA9
uniprot id: A0A6J3DMN8
names: Similarity
messages: Belongs to the heat shock protein 70 family.

219594:EWSR1
gene id: 219594:EWSR1
uniprot id: A0A6J3DW01
uniprot id: A0A6J3E021
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRM TET family.
messages: Nucleus

219594:CHD7
gene id: 219594:CHD7
uniprot id: A0A6J3CEF9
uniprot id: A0A6J3CG30
names: Similarity
messages: Belongs to the SNF2/RAD54 helicase family.

219594:LOC116487209
gene id: 219594:LOC116487209
uniprot id: A0A6J3CL98
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the beta-catenin family.
messages: Belongs to the eutherian X-chromosome-specific Armcx family.
messages: Membrane
messages: Vacuole membrane

219594:CHEK1
gene id: 219594:CHEK1
uniprot id: A0A6J3E7G1
uniprot id: A0A6J3E8U4
names: Similarity
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. NIM1 subfamily.

219594:TOR2A
gene id: 219594:TOR2A
uniprot id: A0A6J3DYL5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ClpA/ClpB family. Torsin subfamily.
messages: Endoplasmic reticulum lumen

219594:NIP7
gene id: 219594:NIP7
uniprot id: A0A6J3DLR4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NIP7 family.
messages: Interacts with pre-ribosome complex.
messages: Required for proper 34S pre-rRNA processing and 60S ribosome subunit assembly.
messages: nucleolus

219594:EDC4
gene id: 219594:EDC4
uniprot id: A0A6J3DPW6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat EDC4 family.
messages: P-body

219594:TRABD2A
gene id: 219594:TRABD2A
uniprot id: A0A6J3EDT6
uniprot id: A0A6J3EJ36
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TIKI family.
messages: Cell membrane
messages: Divalent metal cations. Mn(2+) or Co(2+).
messages: Membrane
messages: Metalloprotease that acts as a negative regulator of the Wnt signaling pathway by mediating the cleavage of the N-terminal residues of a subset of Wnt proteins. Following cleavage, Wnt proteins become oxidized and form large disulfide-bond oligomers, leading to their inactivation.

219594:NDUFV1
gene id: 219594:NDUFV1
uniprot id: A0A6J3D612
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I 51 kDa subunit family.
messages: Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor. Essential for the catalytic activity and assembly of complex I.
messages: Mitochondrion inner membrane

219594:SUMF1
gene id: 219594:SUMF1
uniprot id: A0A6J3DJA8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfatase-modifying factor family.
messages: Endoplasmic reticulum lumen

219594:ABHD15
gene id: 219594:ABHD15
uniprot id: A0A6J3E5C9
names: Similarity
messages: Belongs to the AB hydrolase superfamily. AB hydrolase 4 family.

219594:PLPPR5
gene id: 219594:PLPPR5
uniprot id: A0A6J3D8J9
uniprot id: A0A6J3DEA3
uniprot id: A0A6J3DEK2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PA-phosphatase related phosphoesterase family.
messages: Membrane

219594:SYNGR1
gene id: 219594:SYNGR1
uniprot id: A0A6J3CLD6
uniprot id: A0A6J3CML1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptogyrin family.
messages: Membrane

219594:POLR2C
gene id: 219594:POLR2C
uniprot id: A0A6J3DIW9
names: Similarity
messages: Belongs to the archaeal Rpo3/eukaryotic RPB3 RNA polymerase subunit family.

219594:LTV1
gene id: 219594:LTV1
uniprot id: A0A6J3CST7
names: Similarity
messages: Belongs to the LTV1 family.

219594:SEC62
gene id: 219594:SEC62
uniprot id: A0A6J3DF92
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEC62 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

219594:SMAD5
gene id: 219594:SMAD5
uniprot id: A0A6J3DQB7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dwarfin/SMAD family.
messages: Cytoplasm
messages: Nucleus

219594:GTF2H3
gene id: 219594:GTF2H3
uniprot id: A0A6J3DWH7
uniprot id: A0A6J3E0K8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TFB4 family.
messages: Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to CAK, in RNA transcription by RNA polymerase II. In NER, TFIIH acts by opening DNA around the lesion to allow the excision of the damaged oligonucleotide and its replacement by a new DNA fragment. In transcription, TFIIH has an essential role in transcription initiation. When the pre-initiation complex (PIC) has been established, TFIIH is required for promoter opening and promoter escape. Phosphorylation of the C-terminal tail (CTD) of the largest subunit of RNA polymerase II by the kinase module CAK controls the initiation of transcription.
messages: Nucleus
messages: Part of a TFIID-containing RNA polymerase II pre-initiation complex that is composed of TBP and at least GTF2A1, GTF2A2, GTF2E1, GTF2E2, GTF2F1, GTF2H2, GTF2H3, GTF2H4, GTF2H5, GTF2B, TCEA1, ERCC2, ERCC3, TAF1, TAF2, TAF3, TAF4, TAF5, TAF6, TAF7, TAF8, TAF9, TAF10, TAF11, TAF12 and TAF13. Component of the 7-subunit TFIIH core complex composed of XPB/ERCC3, XPD/ERCC2, GTF2H1, GTF2H2, GTF2H3, GTF2H4 and GTF2H5, which is active in NER. The core complex associates with the 3-subunit CDK-activating kinase (CAK) module composed of CCNH/cyclin H, CDK7 and MNAT1 to form the 10-subunit holoenzyme (holo-TFIIH) active in transcription. Interacts with RARA; the interaction requires prior phosphorylation of RARA on 'Ser-369' which then enhances interaction of RARA with CDK7.

219594:SLC4A4
gene id: 219594:SLC4A4
uniprot id: A0A6J3CTH0
uniprot id: A0A6J3CVS9
uniprot id: A0A6J3CW81
uniprot id: A0A6J3CYJ9
names: Similarity
names: Subcellular Location Annotation
messages: Basolateral cell membrane
messages: Belongs to the anion exchanger (TC 2.A.31) family.
messages: Cell membrane
messages: Lateral cell membrane
messages: Membrane

219594:LOC116488563
gene id: 219594:LOC116488563
uniprot id: A0A6J3CVF4
names: Similarity
messages: Belongs to the FAM47 family.

219594:MDM1
gene id: 219594:MDM1
uniprot id: A0A6J3EIP0
uniprot id: A0A6J3ENT1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MDM1 family.
messages: Nucleus
messages: centriole

219594:FNIP2
gene id: 219594:FNIP2
uniprot id: A0A6J3CYX1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FNIP family.
messages: Lysosome membrane
messages: Membrane

219594:CHRNA5
gene id: 219594:CHRNA5
uniprot id: A0A6J3DM61
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

219594:SMC5
gene id: 219594:SMC5
uniprot id: A0A6J3ECG5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SMC family. SMC5 subfamily.
messages: Chromosome
messages: Nucleus

219594:NCL
gene id: 219594:NCL
uniprot id: A0A6J3DHI5
names: Subcellular Location Annotation
messages: nucleolus

219594:LOC116489950
gene id: 219594:LOC116489950
uniprot id: A0A6J3D2N3
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

219594:NASP
gene id: 219594:NASP
uniprot id: A0A6J3DAF8
uniprot id: A0A6J3DE34
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NASP family.
messages: Nucleus

219594:LOC116486360
gene id: 219594:LOC116486360
uniprot id: A0A6J3CHF6
uniprot id: A0A6J3CIZ3
names: Similarity
messages: Belongs to the AAA ATPase family.

219594:LOC116491834
gene id: 219594:LOC116491834
uniprot id: A0A6J3DF52
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UQCRH/QCR6 family.
messages: Component of the ubiquinol-cytochrome c oxidoreductase, a multisubunit transmembrane complex that is part of the mitochondrial electron transport chain which drives oxidative phosphorylation.
messages: Mitochondrion inner membrane

219594:VKORC1L1
gene id: 219594:VKORC1L1
uniprot id: A0A6J3E432
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VKOR family.
messages: Endoplasmic reticulum membrane
messages: Membrane

219594:LOC116500333
gene id: 219594:LOC116500333
uniprot id: A0A6J3EGU3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

219594:SCRN2
gene id: 219594:SCRN2
uniprot id: A0A6J3E9J1
names: Similarity
messages: Belongs to the peptidase C69 family. Secernin subfamily.

219594:BRD1
gene id: 219594:BRD1
uniprot id: A0A6J3CKF5
uniprot id: A0A6J3CKH5
uniprot id: A0A6J3CRF1
names: Subcellular Location Annotation
messages: Nucleus

219594:CDKN1C
gene id: 219594:CDKN1C
uniprot id: A0A6J3D454
names: Similarity
messages: Belongs to the CDI family.

219594:GALNT2
gene id: 219594:GALNT2
uniprot id: A0A6J3CLL9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
messages: Golgi apparatus membrane
messages: Membrane

219594:DCP1A
gene id: 219594:DCP1A
uniprot id: A0A6J3DK73
names: Similarity
messages: Belongs to the DCP1 family.

219594:ITGB4
gene id: 219594:ITGB4
uniprot id: A0A6J3DW99
uniprot id: A0A6J3E0G7
uniprot id: A0A6J3E194
uniprot id: A0A6J3E2E0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin beta chain family.
messages: Cell membrane
messages: Membrane

219594:CYSLTR1
gene id: 219594:CYSLTR1
uniprot id: A0A6J3DRZ3
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

219594:DIABLO
gene id: 219594:DIABLO
uniprot id: A0A6J3DWZ7
names: Subcellular Location Annotation
messages: Mitochondrion

219594:BCR
gene id: 219594:BCR
uniprot id: A0A6J3DUT7
names: Subcellular Location Annotation
messages: Synapse
messages: axon
messages: dendritic spine

219594:TMPRSS6
gene id: 219594:TMPRSS6
uniprot id: A0A6J3EIM4
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

219594:IL17RD
gene id: 219594:IL17RD
uniprot id: A0A6J3DKW0
names: Subcellular Location Annotation
messages: Membrane

219594:ATL1
gene id: 219594:ATL1
uniprot id: A0A6J3D389
uniprot id: A0A6J3D4A7
names: Similarity
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. GB1/RHD3 GTPase family.

219594:FOXA2
gene id: 219594:FOXA2
uniprot id: A0A6J3CXB6
names: Subcellular Location Annotation
messages: Nucleus

219594:PPP1R14D
gene id: 219594:PPP1R14D
uniprot id: A0A6J3D171
names: Similarity
messages: Belongs to the PP1 inhibitor family.

219594:MMP17
gene id: 219594:MMP17
uniprot id: A0A6J3DUR1
uniprot id: A0A6J3DYU3
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M10A family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Can bind about 5 Ca(2+) ions per subunit.

219594:PTPN22
gene id: 219594:PTPN22
uniprot id: A0A6J3EAU8
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class 4 subfamily.

219594:MRTO4
gene id: 219594:MRTO4
uniprot id: A0A6J3E7C7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associates with the pre-60S ribosomal particle.
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Component of the ribosome assembly machinery. Nuclear paralog of the ribosomal protein P0, it binds pre-60S subunits at an early stage of assembly in the nucleolus, and is replaced by P0 in cytoplasmic pre-60S subunits and mature 80S ribosomes.
messages: Cytoplasm
messages: nucleolus

219594:LETM1
gene id: 219594:LETM1
uniprot id: A0A6J3CY74
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LETM1 family.
messages: Membrane
messages: Mitochondrion inner membrane

219594:MAGI1
gene id: 219594:MAGI1
uniprot id: A0A6J3DDY8
uniprot id: A0A6J3DDZ3
uniprot id: A0A6J3DGR1
uniprot id: A0A6J3DGR6
uniprot id: A0A6J3DHY6
uniprot id: A0A6J3DHZ0
uniprot id: A0A6J3DHZ6
uniprot id: A0A6J3DJK9
uniprot id: A0A6J3DJL3
uniprot id: A0A6J3DK36
uniprot id: A0A6J3DK44
names: Subcellular Location Annotation
messages: Membrane

219594:UBALD1
gene id: 219594:UBALD1
uniprot id: A0A6J3DPT6
names: Similarity
messages: Belongs to the UBALD family.

219594:CFH
gene id: 219594:CFH
uniprot id: A0A6J3DG04
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:LOC116498366
gene id: 219594:LOC116498366
uniprot id: A0A6J3E8P9
names: Similarity
messages: Belongs to the intermediate filament family.

219594:INIP
gene id: 219594:INIP
uniprot id: A0A6J3EHG1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SOSS-C family.
messages: Component of the SOSS complex, a multiprotein complex that functions downstream of the MRN complex to promote DNA repair and G2/M checkpoint. The SOSS complex associates with single-stranded DNA at DNA lesions and influences diverse endpoints in the cellular DNA damage response including cell-cycle checkpoint activation, recombinational repair and maintenance of genomic stability. Required for efficient homologous recombination-dependent repair of double-strand breaks (DSBs).
messages: Component of the SOSS complex.
messages: Nucleus

219594:LOC116501196
gene id: 219594:LOC116501196
uniprot id: A0A6J3EMF7
names: Similarity
messages: Belongs to the thioredoxin family.

219594:ACO1
gene id: 219594:ACO1
uniprot id: A0A6J3EGW5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aconitase/IPM isomerase family.
messages: Cytoplasm

219594:TMEM165
gene id: 219594:TMEM165
uniprot id: A0A6J3CZ57
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GDT1 family.
messages: Membrane

219594:SFXN5
gene id: 219594:SFXN5
uniprot id: A0A6J3CY79
uniprot id: A0A6J3D1Z2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sideroflexin family.
messages: Membrane
messages: Mitochondrion membrane

219594:SMARCD2
gene id: 219594:SMARCD2
uniprot id: A0A6J3E4Q9
names: Similarity
messages: Belongs to the SMARCD family.

219594:CLRN2
gene id: 219594:CLRN2
uniprot id: A0A6J3CZ56
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the clarin family.
messages: Membrane

219594:MFRP
gene id: 219594:MFRP
uniprot id: A0A6J3E969
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:LOC116486807
gene id: 219594:LOC116486807
uniprot id: A0A6J3CP94
names: Similarity
names: Subunit
messages: Belongs to the avian keratin family.
messages: The avian keratins (F-ker, S-ker, C-ker and B-ker) are a complex mixture of very similar polypeptides.

219594:TNFRSF4
gene id: 219594:TNFRSF4
uniprot id: A0A6J3E6C2
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:TLL1
gene id: 219594:TLL1
uniprot id: A0A6J3D126
names: Caution
names: Cofactor
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:MAN2B2
gene id: 219594:MAN2B2
uniprot id: A0A6J3CX17
names: Cofactor
names: Similarity
messages: Belongs to the glycosyl hydrolase 38 family.
messages: Binds 1 zinc ion per subunit.

219594:ADORA3
gene id: 219594:ADORA3
uniprot id: A0A6J3EB17
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for adenosine. The activity of this receptor is mediated by G proteins which inhibit adenylyl cyclase.

219594:GUCY1B1
gene id: 219594:GUCY1B1
uniprot id: A0A6J3CV01
uniprot id: A0A6J3CXA3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
messages: Cytoplasm

219594:LOC116487962
gene id: 219594:LOC116487962
uniprot id: A0A6J3CS29
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cullin family.
messages: Cytoplasm

219594:LOC116496101
gene id: 219594:LOC116496101
uniprot id: A0A6J3DY87
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acts as component of the retromer cargo-selective complex (CSC). The CSC is believed to be the core functional component of retromer or respective retromer complex variants acting to prevent missorting of selected transmembrane cargo proteins into the lysosomal degradation pathway.
messages: Belongs to the VPS29 family.
messages: Endosome membrane

219594:LPIN1
gene id: 219594:LPIN1
uniprot id: A0A6J3CS16
uniprot id: A0A6J3CT48
names: Similarity
messages: Belongs to the lipin family.

219594:PTPN6
gene id: 219594:PTPN6
uniprot id: A0A6J3DSA7
uniprot id: A0A6J3DVA2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class 2 subfamily.
messages: Cytoplasm

219594:LOC116492577
gene id: 219594:LOC116492577
uniprot id: A0A6J3DCQ2
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

219594:ERCC4
gene id: 219594:ERCC4
uniprot id: A0A6J3DWL7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the XPF family.
messages: Nucleus

219594:LOC116499895
gene id: 219594:LOC116499895
uniprot id: A0A6J3EH22
names: Similarity
messages: Belongs to the intermediate filament family.

219594:ADRA1A
gene id: 219594:ADRA1A
uniprot id: A0A6J3EFF9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Cytoplasm
messages: Membrane
messages: Nucleus membrane
messages: caveola

219594:PBX1
gene id: 219594:PBX1
uniprot id: A0A6J3DA27
uniprot id: A0A6J3DDQ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TALE/PBX homeobox family.
messages: Nucleus

219594:LOC116497752
gene id: 219594:LOC116497752
uniprot id: A0A6J3E386
names: Subcellular Location Annotation
messages: Nucleus

219594:CEP57
gene id: 219594:CEP57
uniprot id: A0A6J3EN87
names: Similarity
messages: Belongs to the translokin family.

219594:EDN2
gene id: 219594:EDN2
uniprot id: A0A6J3E585
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endothelin/sarafotoxin family.
messages: Secreted

219594:CLTRN
gene id: 219594:CLTRN
uniprot id: A0A6J3CSI4
uniprot id: A0A6J3CVY5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

219594:APTX
gene id: 219594:APTX
uniprot id: A0A6J3EF74
names: Subcellular Location Annotation
messages: nucleolus
messages: nucleoplasm

219594:ABCD2
gene id: 219594:ABCD2
uniprot id: A0A6J3ER62
names: Subcellular Location Annotation
messages: Membrane

219594:NMNAT3
gene id: 219594:NMNAT3
uniprot id: A0A6J3DIT6
names: Similarity
messages: Belongs to the eukaryotic NMN adenylyltransferase family.

219594:SPINK2
gene id: 219594:SPINK2
uniprot id: A0A6J3CVA7
names: Subcellular Location Annotation
messages: Secreted

219594:LOC116501848
gene id: 219594:LOC116501848
uniprot id: A0A6J3EN90
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M10A family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Can bind about 5 Ca(2+) ions per subunit.

219594:HYLS1
gene id: 219594:HYLS1
uniprot id: A0A6J3E2W5
uniprot id: A0A6J3E7V3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HYLS1 family.
messages: centriole
messages: cilium

219594:ZDHHC3
gene id: 219594:ZDHHC3
uniprot id: A0A6J3CI35
uniprot id: A0A6J3CJ59
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

219594:LOC116502240
gene id: 219594:LOC116502240
uniprot id: A0A6J3EKX9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

219594:ATG7
gene id: 219594:ATG7
uniprot id: A0A6J3DL57
uniprot id: A0A6J3DLM4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATG7 family.
messages: Cytoplasm
messages: E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production. Modulates p53/TP53 activity to regulate cell cycle and survival during metabolic stress.
messages: Homodimer.
messages: Preautophagosomal structure

219594:ANXA2
gene id: 219594:ANXA2
uniprot id: A0A6J3DMK7
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: A pair of annexin repeats may form one binding site for calcium and phospholipid.
messages: Belongs to the annexin family.
messages: Membrane
messages: basement membrane

219594:API5
gene id: 219594:API5
uniprot id: A0A6J3CZ25
names: Similarity
messages: Belongs to the API5 family.

219594:RANBP10
gene id: 219594:RANBP10
uniprot id: A0A6J3DIL9
uniprot id: A0A6J3DMQ9
names: Similarity
messages: Belongs to the RANBP9/10 family.

219594:ADAMTS1
gene id: 219594:ADAMTS1
uniprot id: A0A6J3E1F7
names: Caution
names: Cofactor
names: Subcellular Location Annotation
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

219594:C17H12orf49
gene id: 219594:C17H12orf49
uniprot id: A0A6J3DZ31
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPRING family.
messages: Golgi apparatus membrane
messages: Membrane

219594:SAMD8
gene id: 219594:SAMD8
uniprot id: A0A6J3DC51
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sphingomyelin synthase family.
messages: Membrane

219594:RNASEH1
gene id: 219594:RNASEH1
uniprot id: A0A6J3CPV5
uniprot id: A0A6J3CVZ3
names: Function
names: Similarity
messages: Belongs to the RNase H family.
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.

219594:PRR15
gene id: 219594:PRR15
uniprot id: A0A6J3CCG7
names: Similarity
messages: Belongs to the PRR15 family.

219594:MOK
gene id: 219594:MOK
uniprot id: A0A6J3CZ43
uniprot id: A0A6J3D1L3
uniprot id: A0A6J3D1N9
uniprot id: A0A6J3D1P5
uniprot id: A0A6J3D448
uniprot id: A0A6J3D538
names: Similarity
messages: Belongs to the protein kinase superfamily.

219594:ROGDI
gene id: 219594:ROGDI
uniprot id: A0A6J3DQI8
uniprot id: A0A6J3DWP4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the rogdi family.
messages: Presynapse
messages: Vesicle
messages: synaptic vesicle

219594:MCM4
gene id: 219594:MCM4
uniprot id: A0A6J3CJJ4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as component of the MCM2-7 complex (MCM complex) which is the replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity.
messages: Belongs to the MCM family.
messages: Chromosome
messages: Component of the MCM2-7 complex.
messages: Nucleus

219594:CHMP6
gene id: 219594:CHMP6
uniprot id: A0A6J3E0G0
names: Similarity
messages: Belongs to the SNF7 family.

219594:MUTYH
gene id: 219594:MUTYH
uniprot id: A0A6J3DA93
names: Cofactor
names: Function
names: Similarity
messages: Adenine glycosylase active on G-A mispairs.
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.

219594:STMN2
gene id: 219594:STMN2
uniprot id: A0A6J3CME0
names: Similarity
messages: Belongs to the stathmin family.

219594:GPI
gene id: 219594:GPI
uniprot id: A0A6J3DIV8
names: Similarity
messages: Belongs to the GPI family.

219594:CASR
gene id: 219594:CASR
uniprot id: A0A6J3EJB6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

219594:ADTRP
gene id: 219594:ADTRP
uniprot id: A0A6J3CQJ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIG1 family.
messages: Membrane

219594:NIT1
gene id: 219594:NIT1
uniprot id: A0A6J3E9Z8
uniprot id: A0A6J3EGR3
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.

219594:VPS33B
gene id: 219594:VPS33B
uniprot id: A0A6J3DN03
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STXBP/unc-18/SEC1 family.
messages: Endosome membrane
messages: Late endosome membrane
messages: Lysosome membrane

219594:HACL1
gene id: 219594:HACL1
uniprot id: A0A6J3CI83
names: Similarity
messages: Belongs to the TPP enzyme family.

219594:ACSS1
gene id: 219594:ACSS1
uniprot id: A0A6J3CMD7
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

219594:CASS4
gene id: 219594:CASS4
uniprot id: A0A6J3DXN3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CAS family.
messages: focal adhesion

219594:LOC116494267
gene id: 219594:LOC116494267
uniprot id: A0A6J3DMU0
uniprot id: A0A6J3DPM4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.
messages: Cell membrane
messages: Membrane

219594:SLC16A6
gene id: 219594:SLC16A6
uniprot id: A0A6J3E0E8
names: Subcellular Location Annotation
messages: Membrane

219594:FAM91A1
gene id: 219594:FAM91A1
uniprot id: A0A6J3CJW7
names: Similarity
messages: Belongs to the FAM91 family.

219594:PEX1
gene id: 219594:PEX1
uniprot id: A0A6J3CM38
uniprot id: A0A6J3CNN4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAA ATPase family.
messages: cytosol

219594:PGAM1
gene id: 219594:PGAM1
uniprot id: A0A6J3DD83
names: Similarity
messages: Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.

219594:LOC116494923
gene id: 219594:LOC116494923
uniprot id: A0A6J3DTH1
names: Subcellular Location Annotation
messages: Secreted

219594:SLC25A48
gene id: 219594:SLC25A48
uniprot id: A0A6J3DSW9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

219594:LOC116492695
gene id: 219594:LOC116492695
uniprot id: A0A6J3DG00
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

219594:CLUL1
gene id: 219594:CLUL1
uniprot id: A0A6J3CHW8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the clusterin family.
messages: Secreted

219594:TIMM9
gene id: 219594:TIMM9
uniprot id: A0A6J3D3X7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the small Tim family.
messages: Heterohexamer.
messages: Mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space.
messages: Mitochondrion inner membrane
messages: The twin CX3C motif contains 4 conserved Cys residues that form 2 disulfide bonds in the mitochondrial intermembrane space.

219594:LOC116493010
gene id: 219594:LOC116493010
uniprot id: A0A6J3DKY1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ITIH family.
messages: Secreted

219594:ACTN2
gene id: 219594:ACTN2
uniprot id: A0A6J3CNI6
uniprot id: A0A6J3CQH2
uniprot id: A0A6J3CR76
uniprot id: A0A6J3CR79
uniprot id: A0A6J3CTG5
uniprot id: A0A6J3CTG7
names: Similarity
messages: Belongs to the alpha-actinin family.

219594:LOC116496310
gene id: 219594:LOC116496310
uniprot id: A0A6J3DWY1
names: Subcellular Location Annotation
messages: Membrane

219594:DDX55
gene id: 219594:DDX55
uniprot id: A0A6J3E058
names: Domain
names: Function
names: Similarity
messages: Belongs to the DEAD box helicase family.
messages: RNA helicase.
messages: The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.

219594:MAN1A1
gene id: 219594:MAN1A1
uniprot id: A0A6J3CQQ2
names: Similarity
messages: Belongs to the glycosyl hydrolase 47 family.

219594:CDR2L
gene id: 219594:CDR2L
uniprot id: A0A6J3DXT7
names: Similarity
messages: Belongs to the CDR2 family.

219594:FBXO25
gene id: 219594:FBXO25
uniprot id: A0A6J3CPH0
uniprot id: A0A6J3CRH4
uniprot id: A0A6J3CVK1
names: Subcellular Location Annotation
messages: Nucleus

219594:CNMD
gene id: 219594:CNMD
uniprot id: A0A6J3EQK0
names: Similarity
messages: Belongs to the chondromodulin-1 family.

219594:GJB3
gene id: 219594:GJB3
uniprot id: A0A6J3E3R1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

219594:LOC116493885
gene id: 219594:LOC116493885
uniprot id: A0A6J3DPD0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome c oxidase IV family.
messages: Component of the cytochrome c oxidase (complex IV, CIV), a multisubunit enzyme composed of 14 subunits.
messages: Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.
messages: Membrane
messages: Mitochondrion inner membrane

219594:HACD4
gene id: 219594:HACD4
uniprot id: A0A6J3EKK2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the very long-chain fatty acids dehydratase HACD family.
messages: Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

219594:B4GALT4
gene id: 219594:B4GALT4
uniprot id: A0A6J3DWS1
uniprot id: A0A6J3E2S2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 7 family.
messages: Golgi apparatus membrane
messages: Membrane
messages: Responsible for the synthesis of complex-type N-linked oligosaccharides in many glycoproteins as well as the carbohydrate moieties of glycolipids.

219594:AGBL5
gene id: 219594:AGBL5
uniprot id: A0A6J3CPY3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M14 family.
messages: Midbody
messages: Nucleus
messages: cytosol
messages: spindle

219594:SPIN1
gene id: 219594:SPIN1
uniprot id: A0A6J3EHT8
names: Similarity
messages: Belongs to the SPIN/STSY family.

219594:PSMC3IP
gene id: 219594:PSMC3IP
uniprot id: A0A6J3E630
uniprot id: A0A6J3E922
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HOP2 family.
messages: Nucleus

219594:DHX15
gene id: 219594:DHX15
uniprot id: A0A6J3CUR6
names: Similarity
messages: Belongs to the DEAD box helicase family. DEAH subfamily. DDX15/PRP43 sub-subfamily.

219594:RAD9A
gene id: 219594:RAD9A
uniprot id: A0A6J3D4B0
names: Similarity
messages: Belongs to the rad9 family.

219594:FAM118A
gene id: 219594:FAM118A
uniprot id: A0A6J3CYS2
names: Similarity
messages: Belongs to the FAM118 family.

219594:IL13RA2
gene id: 219594:IL13RA2
uniprot id: A0A6J3DT78
names: Subcellular Location Annotation
messages: Membrane

219594:TMEM163
gene id: 219594:TMEM163
uniprot id: A0A6J3D2I5
uniprot id: A0A6J3D8E3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM163 family.
messages: Membrane
messages: synaptic vesicle membrane

219594:NT5C2
gene id: 219594:NT5C2
uniprot id: A0A6J3D9X8
names: Cofactor
names: Similarity
messages: Belongs to the 5'(3')-deoxyribonucleotidase family.
messages: Binds 1 Mg(2+) ion per subunit.

219594:CCSER2
gene id: 219594:CCSER2
uniprot id: A0A6J3D677
uniprot id: A0A6J3D8X4
uniprot id: A0A6J3D9G3
uniprot id: A0A6J3D9G8
uniprot id: A0A6J3DBN6
uniprot id: A0A6J3DC47
names: Similarity
messages: Belongs to the CCSER family.

219594:PPP6C
gene id: 219594:PPP6C
uniprot id: A0A6J3E4N0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PPP phosphatase family.
messages: Cytoplasm

219594:SYNM
gene id: 219594:SYNM
uniprot id: A0A6J3DM81
names: Similarity
messages: Belongs to the intermediate filament family.

219594:EIF5A2
gene id: 219594:EIF5A2
uniprot id: A0A6J3DH54
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eIF-5A family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Translation factor that promotes translation elongation and termination, particularly upon ribosome stalling at specific amino acid sequence contexts. Binds between the exit (E) and peptidyl (P) site of the ribosome and promotes rescue of stalled ribosome: specifically required for efficient translation of polyproline-containing peptides as well as other motifs that stall the ribosome. Acts as ribosome quality control (RQC) cofactor by joining the RQC complex to facilitate peptidyl transfer during CAT tailing step.
messages: eIF-5A seems to be the only eukaryotic protein to have a hypusine residue which is a post-translational modification of a lysine by the addition of a butylamino group.

219594:SLC20A1
gene id: 219594:SLC20A1
uniprot id: A0A6J3E8S9
uniprot id: A0A6J3EDX0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
messages: Membrane
messages: Sodium-phosphate symporter.

219594:ATG13
gene id: 219594:ATG13
uniprot id: A0A6J3CY92
uniprot id: A0A6J3D0S0
uniprot id: A0A6J3D0U9
uniprot id: A0A6J3D386
uniprot id: A0A6J3D4A2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATG13 family. Metazoan subfamily.
messages: Preautophagosomal structure

219594:DDX58
gene id: 219594:DDX58
uniprot id: A0A6J3EIR0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the helicase family. RLR subfamily.
messages: Cytoplasm

219594:MYH11
gene id: 219594:MYH11
uniprot id: A0A6J3DSZ4
uniprot id: A0A6J3DWU2
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.

219594:ZDHHC14
gene id: 219594:ZDHHC14
uniprot id: A0A6J3CKI0
uniprot id: A0A6J3CM17
uniprot id: A0A6J3CN56
uniprot id: A0A6J3CQD5
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

219594:C25H6orf89
gene id: 219594:C25H6orf89
uniprot id: A0A6J3EB66
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Golgi apparatus membrane
messages: Membrane

219594:SCD5
gene id: 219594:SCD5
uniprot id: A0A6J3CVB8
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fatty acid desaturase type 1 family.
messages: Membrane
messages: The histidine box domains are involved in binding the catalytic metal ions.

219594:LOC116487462
gene id: 219594:LOC116487462
uniprot id: A0A6J3CTU8
names: Similarity
messages: Belongs to the GST superfamily. Alpha family.

219594:ZNF622
gene id: 219594:ZNF622
uniprot id: A0A6J3CNG2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the REI1 family.
messages: Cytoplasm

219594:GPD1L
gene id: 219594:GPD1L
uniprot id: A0A6J3CF36
names: Similarity
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.

219594:CORIN
gene id: 219594:CORIN
uniprot id: A0A6J3CTZ4
names: Caution
names: Subcellular Location Annotation
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:UGCG
gene id: 219594:UGCG
uniprot id: A0A6J3EFK5
names: Similarity
messages: Belongs to the glycosyltransferase 2 family.

219594:LOC116490153
gene id: 219594:LOC116490153
uniprot id: A0A6J3D137
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

219594:DBR1
gene id: 219594:DBR1
uniprot id: A0A6J3DGY2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lariat debranching enzyme family.
messages: Nucleus

219594:LOC116489584
gene id: 219594:LOC116489584
uniprot id: A0A6J3D414
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

219594:SELENOO
gene id: 219594:SELENOO
uniprot id: A0A6J3ECU6
names: Similarity
messages: Belongs to the SELO family.

219594:KIFBP
gene id: 219594:KIFBP
uniprot id: A0A6J3D9W4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KIF-binding protein family.
messages: cytoskeleton

219594:CLUH
gene id: 219594:CLUH
uniprot id: A0A6J3DYZ2
uniprot id: A0A6J3E382
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CLU family.
messages: Cytoplasm
messages: Cytoplasmic granule
messages: mRNA-binding protein involved in proper cytoplasmic distribution of mitochondria. Specifically binds mRNAs of nuclear-encoded mitochondrial proteins in the cytoplasm and regulates transport or translation of these transcripts close to mitochondria, playing a role in mitochondrial biogenesis.

219594:COQ6
gene id: 219594:COQ6
uniprot id: A0A6J3D4D7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UbiH/COQ6 family.
messages: Cell projection
messages: Component of a multi-subunit COQ enzyme complex, composed of at least COQ3, COQ4, COQ5, COQ6, COQ7 and COQ9. Interacts with ADCK4 and COQ7.
messages: FAD-dependent monooxygenase required for the C5-ring hydroxylation during ubiquinone biosynthesis. Catalyzes the hydroxylation of 3-polyprenyl-4-hydroxybenzoic acid to 3-polyprenyl-4,5-dihydroxybenzoic acid. The electrons required for the hydroxylation reaction may be funneled indirectly from NADPH via a ferredoxin/ferredoxin reductase system to COQ6.
messages: Golgi apparatus
messages: Mitochondrion inner membrane

219594:EPDR1
gene id: 219594:EPDR1
uniprot id: A0A6J3CGC1
names: Similarity
messages: Belongs to the ependymin family.

219594:TNS4
gene id: 219594:TNS4
uniprot id: A0A6J3E5J6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PTEN phosphatase protein family.
messages: focal adhesion

219594:RYR3
gene id: 219594:RYR3
uniprot id: A0A6J3D1W0
uniprot id: A0A6J3D1W7
uniprot id: A0A6J3D4A0
uniprot id: A0A6J3D4M5
uniprot id: A0A6J3D4M9
uniprot id: A0A6J3D6V4
uniprot id: A0A6J3D7P8
uniprot id: A0A6J3D7Q4
names: Subcellular Location Annotation
messages: Membrane
messages: Sarcoplasmic reticulum membrane

219594:PIGC
gene id: 219594:PIGC
uniprot id: A0A6J3DG20
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PIGC family.
messages: Membrane

219594:LOC116502369
gene id: 219594:LOC116502369
uniprot id: A0A6J3EK32
names: Similarity
names: Subunit
messages: Belongs to the histone H3 family.
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

219594:AKT3
gene id: 219594:AKT3
uniprot id: A0A6J3CSS2
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. RAC subfamily.

219594:LOC116501333
gene id: 219594:LOC116501333
uniprot id: A0A6J3EG83
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

219594:COPS7B
gene id: 219594:COPS7B
uniprot id: A0A6J3DIR8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CSN7/EIF3M family. CSN7 subfamily.
messages: Component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF-type complexes such as SCF, CSA or DDB2. The complex is also involved in phosphorylation of p53/TP53, JUN, I-kappa-B-alpha/NFKBIA, ITPK1 and IRF8/ICSBP, possibly via its association with CK2 and PKD kinases. CSN-dependent phosphorylation of TP53 and JUN promotes and protects degradation by the Ubl system, respectively.
messages: Cytoplasm
messages: Nucleus

219594:EEF1A2
gene id: 219594:EEF1A2
uniprot id: A0A6J3DRT4
names: Function
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

219594:PRR5
gene id: 219594:PRR5
uniprot id: A0A6J3D3E5
uniprot id: A0A6J3D3H9
names: Similarity
messages: Belongs to the PROTOR family.

219594:ADA2
gene id: 219594:ADA2
uniprot id: A0A6J3DPR6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. ADGF subfamily.
messages: Secreted

219594:LOC116500241
gene id: 219594:LOC116500241
uniprot id: A0A6J3EGJ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

219594:MAP2K4
gene id: 219594:MAP2K4
uniprot id: A0A6J3DVV1
uniprot id: A0A6J3E009
uniprot id: A0A6J3E0U3
names: Similarity
messages: Belongs to the protein kinase superfamily.

219594:UGDH
gene id: 219594:UGDH
uniprot id: A0A6J3CUV7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.
messages: Homohexamer.
messages: Involved in the biosynthesis of glycosaminoglycans; hyaluronan, chondroitin sulfate, and heparan sulfate.

219594:LOC116491433
gene id: 219594:LOC116491433
uniprot id: A0A6J3DAJ0
names: Similarity
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.

219594:AQP10
gene id: 219594:AQP10
uniprot id: A0A6J3EDN6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Cell membrane
messages: Membrane

219594:LOC116494123
gene id: 219594:LOC116494123
uniprot id: A0A6J3DMB2
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

219594:NDUFB4
gene id: 219594:NDUFB4
uniprot id: A0A6J3DGL2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFB4 subunit family.
messages: Complex I is composed of 45 different subunits.
messages: Mitochondrion inner membrane

219594:DNMBP
gene id: 219594:DNMBP
uniprot id: A0A6J3DDU8
names: Subcellular Location Annotation
messages: Cell junction
messages: Golgi stack
messages: Synapse
messages: cytoskeleton

219594:PRKCB
gene id: 219594:PRKCB
uniprot id: A0A6J3DQP7
uniprot id: A0A6J3DV26
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.
messages: Binds 3 Ca(2+) ions per subunit. The ions are bound to the C2 domain.
messages: Cytoplasm
messages: Membrane
messages: Nucleus

219594:HS6ST3
gene id: 219594:HS6ST3
uniprot id: A0A6J3EQJ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 6-O-sulfation enzyme which catalyzes the transfer of sulfate from 3'-phosphoadenosine 5'-phosphosulfate (PAPS) to position 6 of the N-sulfoglucosamine residue (GlcNS) of heparan sulfate.
messages: Belongs to the sulfotransferase 6 family.
messages: Membrane

219594:PLOD1
gene id: 219594:PLOD1
uniprot id: A0A6J3E773
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane

219594:NSUN4
gene id: 219594:NSUN4
uniprot id: A0A6J3DD89
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.

219594:TARS1
gene id: 219594:TARS1
uniprot id: A0A6J3EL99
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.

219594:PMM2
gene id: 219594:PMM2
uniprot id: A0A6J3DTV6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic PMM family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the synthesis of the GDP-mannose and dolichol-phosphate-mannose required for a number of critical mannosyl transfer reactions.

219594:ZCCHC8
gene id: 219594:ZCCHC8
uniprot id: A0A6J3DUP2
uniprot id: A0A6J3DYT0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZCCHC8 family.
messages: nucleoplasm

219594:SFXN4
gene id: 219594:SFXN4
uniprot id: A0A6J3D9U2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sideroflexin family.
messages: Membrane

219594:SNX20
gene id: 219594:SNX20
uniprot id: A0A6J3DNG5
names: Subcellular Location Annotation
messages: Early endosome membrane
messages: Membrane

219594:NINJ1
gene id: 219594:NINJ1
uniprot id: A0A6J3DKG5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ninjurin family.
messages: Membrane

219594:DYRK3
gene id: 219594:DYRK3
uniprot id: A0A6J3EAW3
uniprot id: A0A6J3ECF6
names: Similarity
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MNB/DYRK subfamily.

219594:SLC7A5
gene id: 219594:SLC7A5
uniprot id: A0A6J3DNW8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. L-type amino acid transporter (LAT) (TC 2.A.3.8) family.
messages: Cell membrane
messages: Membrane

219594:UROC1
gene id: 219594:UROC1
uniprot id: A0A6J3DL38
names: Similarity
messages: Belongs to the urocanase family.

219594:XKR8
gene id: 219594:XKR8
uniprot id: A0A6J3E9U0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the XK family.
messages: Membrane

219594:MSMP
gene id: 219594:MSMP
uniprot id: A0A6J3EJC0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the beta-microseminoprotein family.
messages: Secreted

219594:CERS3
gene id: 219594:CERS3
uniprot id: A0A6J3DHF0
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Nucleus

219594:BASP1
gene id: 219594:BASP1
uniprot id: A0A6J3CMM7
names: Similarity
messages: Belongs to the BASP1 family.

219594:CDCA8
gene id: 219594:CDCA8
uniprot id: A0A6J3E4Q3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the borealin family.
messages: centromere

219594:SUGP2
gene id: 219594:SUGP2
uniprot id: A0A6J3ECG1
names: Subcellular Location Annotation
messages: Nucleus

219594:CRH
gene id: 219594:CRH
uniprot id: A0A6J3CK35
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sauvagine/corticotropin-releasing factor/urotensin I family.
messages: Secreted

219594:KCNH7
gene id: 219594:KCNH7
uniprot id: A0A6J3D361
uniprot id: A0A6J3D5N9
uniprot id: A0A6J3D621
uniprot id: A0A6J3D886
uniprot id: A0A6J3D892
uniprot id: A0A6J3D8Z4
uniprot id: A0A6J3D8Z9
names: Subcellular Location Annotation
messages: Membrane

219594:RFLNA
gene id: 219594:RFLNA
uniprot id: A0A6J3E0V0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Refilin family.
messages: Interacts with FLNA and FLNB.
messages: cytoskeleton

219594:MTX1
gene id: 219594:MTX1
uniprot id: A0A6J3EB23
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metaxin family.
messages: Membrane
messages: Mitochondrion outer membrane

219594:SNX31
gene id: 219594:SNX31
uniprot id: A0A6J3CDH2
names: Similarity
messages: Belongs to the sorting nexin family.

219594:LOC116501374
gene id: 219594:LOC116501374
uniprot id: A0A6J3EN16
names: Subcellular Location Annotation
messages: Secreted

219594:HSD17B2
gene id: 219594:HSD17B2
uniprot id: A0A6J3DNQ8
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

219594:LOC116485351
gene id: 219594:LOC116485351
uniprot id: A0A6J3CGF5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IL-7/IL-9 family.
messages: Secreted

219594:URM1
gene id: 219594:URM1
uniprot id: A0A6J3E4D0
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a sulfur carrier required for 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Serves as sulfur donor in tRNA 2-thiolation reaction by being thiocarboxylated (-COSH) at its C-terminus by MOCS3. The sulfur is then transferred to tRNA to form 2-thiolation of mcm(5)S(2)U. Also acts as a ubiquitin-like protein (UBL) that is covalently conjugated via an isopeptide bond to lysine residues of target proteins. The thiocarboxylated form serves as substrate for conjugation and oxidative stress specifically induces the formation of UBL-protein conjugates.
messages: Belongs to the URM1 family.
messages: C-terminal thiocarboxylation occurs in 2 steps, it is first acyl-adenylated (-COAMP) via the hesA/moeB/thiF part of MOCS3, then thiocarboxylated (-COSH) via the rhodanese domain of MOCS3.
messages: Cytoplasm

219594:ARFGEF1
gene id: 219594:ARFGEF1
uniprot id: A0A6J3CCC7
uniprot id: A0A6J3CE05
names: Subcellular Location Annotation
messages: Golgi apparatus
messages: perinuclear region

219594:BICC1
gene id: 219594:BICC1
uniprot id: A0A6J3D6H2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BicC family.
messages: Cytoplasm

219594:LOC116498761
gene id: 219594:LOC116498761
uniprot id: A0A6J3EAD8
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Opsin subfamily.
messages: Contains one covalently linked retinal chromophore.
messages: Membrane

219594:RBM15
gene id: 219594:RBM15
uniprot id: A0A6J3E5Y2
names: Similarity
messages: Belongs to the RRM Spen family.

219594:CSNK2A1
gene id: 219594:CSNK2A1
uniprot id: A0A6J3DTT9
names: Similarity
messages: Belongs to the protein kinase superfamily.

219594:GALNT16
gene id: 219594:GALNT16
uniprot id: A0A6J3D287
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
messages: Golgi apparatus membrane
messages: Membrane

219594:SRP68
gene id: 219594:SRP68
uniprot id: A0A6J3DY65
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SRP68 family.
messages: Component of the signal recognition particle (SRP) complex, a ribonucleoprotein complex that mediates the cotranslational targeting of secretory and membrane proteins to the endoplasmic reticulum (ER). The SRP complex interacts with the signal sequence in nascent secretory and membrane proteins and directs them to the membrane of the ER.
messages: Cytoplasm
messages: nucleolus

219594:HOMER2
gene id: 219594:HOMER2
uniprot id: A0A6J3DJZ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Homer family.
messages: Cytoplasm
messages: Postsynaptic density
messages: Synapse

219594:LOC116500235
gene id: 219594:LOC116500235
uniprot id: A0A6J3EG81
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the immunoglobulin superfamily. BTN/MOG family.
messages: Membrane

219594:BPNT1
gene id: 219594:BPNT1
uniprot id: A0A6J3CV31
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

219594:CDC42EP4
gene id: 219594:CDC42EP4
uniprot id: A0A6J3E120
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BORG/CEP family.
messages: Endomembrane system

219594:MCTP1
gene id: 219594:MCTP1
uniprot id: A0A6J3EDS9
uniprot id: A0A6J3EF89
uniprot id: A0A6J3EIN3
uniprot id: A0A6J3EJ29
uniprot id: A0A6J3EKL0
names: Subcellular Location Annotation
messages: Membrane

219594:C5
gene id: 219594:C5
uniprot id: A0A6J3E229
names: Subcellular Location Annotation
messages: Secreted

219594:TP53BP1
gene id: 219594:TP53BP1
uniprot id: A0A6J3DHX1
uniprot id: A0A6J3DM09
uniprot id: A0A6J3DP08
names: Subcellular Location Annotation
messages: Nucleus

219594:LOC116499761
gene id: 219594:LOC116499761
uniprot id: A0A6J3EGN1
names: Similarity
names: Subunit
messages: Belongs to the avian keratin family.
messages: The avian keratins (F-ker, S-ker, C-ker and B-ker) are a complex mixture of very similar polypeptides.

219594:C1QBP
gene id: 219594:C1QBP
uniprot id: A0A6J3DZB6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MAM33 family.
messages: Cell membrane

219594:LOC116500218
gene id: 219594:LOC116500218
uniprot id: A0A6J3EI27
names: Similarity
messages: Belongs to the nuclear hormone receptor family. NR2 subfamily.

219594:SLC24A5
gene id: 219594:SLC24A5
uniprot id: A0A6J3DLQ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. SLC24A subfamily.
messages: Membrane

219594:LOC116486626
gene id: 219594:LOC116486626
uniprot id: A0A6J3CIV2
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily.

219594:TSPAN10
gene id: 219594:TSPAN10
uniprot id: A0A6J3E2V5
names: Subcellular Location Annotation
messages: Membrane

219594:ALDH3B1
gene id: 219594:ALDH3B1
uniprot id: A0A6J3D3F6
uniprot id: A0A6J3D607
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

219594:CHD1
gene id: 219594:CHD1
uniprot id: A0A6J3ED15
uniprot id: A0A6J3EI67
uniprot id: A0A6J3EJU9
names: Subcellular Location Annotation
messages: Nucleus

219594:LOC116500500
gene id: 219594:LOC116500500
uniprot id: A0A6J3ECK6
names: Similarity
messages: Belongs to the avidin/streptavidin family.

219594:SMAD4
gene id: 219594:SMAD4
uniprot id: A0A6J3ECB0
uniprot id: A0A6J3EH45
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dwarfin/SMAD family.
messages: Cytoplasm
messages: Nucleus

219594:FAS
gene id: 219594:FAS
uniprot id: A0A6J3DE07
uniprot id: A0A6J3DEA9
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane raft

219594:POLR2L
gene id: 219594:POLR2L
uniprot id: A0A6J3D4X6
names: Similarity
messages: Belongs to the archaeal Rpo10/eukaryotic RPB10 RNA polymerase subunit family.

219594:PCNX2
gene id: 219594:PCNX2
uniprot id: A0A6J3CKR3
uniprot id: A0A6J3CRQ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pecanex family.
messages: Membrane

219594:LSM6
gene id: 219594:LSM6
uniprot id: A0A6J3CUL9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the snRNP Sm proteins family. SmF/LSm6 subfamily.
messages: Nucleus

219594:SLC39A9
gene id: 219594:SLC39A9
uniprot id: A0A6J3D4Q8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZIP transporter (TC 2.A.5) family.
messages: Cell membrane
messages: Membrane
messages: Mitochondrion
messages: Nucleus
messages: Transports zinc ions across cell and organelle membranes into the cytoplasm and regulates intracellular zinc homeostasis. Participates in the zinc ions efflux out of the secretory compartments. Also functions as membrane androgen receptor that mediates, through a G protein, the non-classical androgen signaling pathway, characterized by the activation of MAPK3/MAPK1 (Erk1/2) and transcription factors CREB1 or ATF1. Moreover, has dual functions as membrane-bound androgen receptor and as an androgen-dependent zinc transporter both of which are mediated through an inhibitory G protein (Gi) that mediates both MAP kinase and zinc signaling leading to the androgen-dependent apoptotic process.
messages: perinuclear region
messages: trans-Golgi network membrane

219594:ADAMTS19
gene id: 219594:ADAMTS19
uniprot id: A0A6J3EEL2
names: Caution
names: Cofactor
names: Subcellular Location Annotation
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

219594:NTS
gene id: 219594:NTS
uniprot id: A0A6J3DLW8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the neurotensin family.
messages: Neurotensin may play an endocrine or paracrine role in the regulation of fat metabolism. It causes contraction of smooth muscle.
messages: Secreted
messages: Vesicle
messages: secretory vesicle

219594:HOOK3
gene id: 219594:HOOK3
uniprot id: A0A6J3EHD1
uniprot id: A0A6J3EL34
uniprot id: A0A6J3EL57
uniprot id: A0A6J3EMJ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the hook family.
messages: cytoskeleton

219594:TMBIM6
gene id: 219594:TMBIM6
uniprot id: A0A6J3EFU7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

219594:PTPN4
gene id: 219594:PTPN4
uniprot id: A0A6J3D3W5
uniprot id: A0A6J3D6H4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class subfamily.
messages: cytoskeleton

219594:HCRTR2
gene id: 219594:HCRTR2
uniprot id: A0A6J3CQ61
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

219594:CDK9
gene id: 219594:CDK9
uniprot id: A0A6J3DZQ1
names: Similarity
messages: Belongs to the protein kinase superfamily.

219594:TADA1
gene id: 219594:TADA1
uniprot id: A0A6J3DE12
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TADA1 family.
messages: Nucleus
messages: Probably involved in transcriptional regulation.

219594:RNFT2
gene id: 219594:RNFT2
uniprot id: A0A6J3DWR1
names: Subcellular Location Annotation
messages: Membrane

219594:LOC116491320
gene id: 219594:LOC116491320
uniprot id: A0A6J3D6M6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

219594:STAMBP
gene id: 219594:STAMBP
uniprot id: A0A6J3EDF9
names: Similarity
messages: Belongs to the peptidase M67C family.

219594:CPS1
gene id: 219594:CPS1
uniprot id: A0A6J3D701
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:LOC116489632
gene id: 219594:LOC116489632
uniprot id: A0A6J3D337
uniprot id: A0A6J3D462
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM263 family.
messages: Membrane

219594:CMTR1
gene id: 219594:CMTR1
uniprot id: A0A6J3CQV3
names: Function
names: Subcellular Location Annotation
messages: Nucleus
messages: S-adenosyl-L-methionine-dependent methyltransferase that mediates RNA cap1 2'-O-ribose methylation to the 5'-cap structure of RNAs. Methylates the ribose of the first nucleotide of a m(7)GpppG-capped mRNA to produce m(7)GpppNmp (cap1).
messages: S-adenosyl-L-methionine-dependent methyltransferase that mediates mRNA cap1 2'-O-ribose methylation to the 5'-cap structure of mRNAs. Methylates the ribose of the first nucleotide of a m(7)GpppG-capped mRNA and small nuclear RNA (snRNA) to produce m(7)GpppRm (cap1). Displays a preference for cap0 transcripts. Cap1 modification is linked to higher levels of translation. May be involved in the interferon response pathway.

219594:BTF3
gene id: 219594:BTF3
uniprot id: A0A6J3EI22
names: Similarity
messages: Belongs to the NAC-beta family.

219594:MPP5
gene id: 219594:MPP5
uniprot id: A0A6J3D2K7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MAGUK family.
messages: Cell membrane
messages: tight junction

219594:CHST13
gene id: 219594:CHST13
uniprot id: A0A6J3DEZ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 2 family.
messages: Golgi apparatus membrane
messages: Membrane

219594:PDSS2
gene id: 219594:PDSS2
uniprot id: A0A6J3CV02
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

219594:ERBB2
gene id: 219594:ERBB2
uniprot id: A0A6J3E9R9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. EGF receptor subfamily.
messages: Membrane

219594:IDS
gene id: 219594:IDS
uniprot id: A0A6J3DKW2
names: Similarity
messages: Belongs to the sulfatase family.

219594:MID1
gene id: 219594:MID1
uniprot id: A0A6J3DH69
names: Subcellular Location Annotation
messages: cytoskeleton

219594:OXSM
gene id: 219594:OXSM
uniprot id: A0A6J3CH89
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

219594:LOC116490011
gene id: 219594:LOC116490011
uniprot id: A0A6J3D658
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

219594:LOC116488042
gene id: 219594:LOC116488042
uniprot id: A0A6J3CSW7
names: Similarity
messages: Belongs to the GST superfamily. Alpha family.

219594:TNFRSF1B
gene id: 219594:TNFRSF1B
uniprot id: A0A6J3E5H3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:GABARAPL2
gene id: 219594:GABARAPL2
uniprot id: A0A6J3DL02
names: Similarity
messages: Belongs to the ATG8 family.

219594:GGT5
gene id: 219594:GGT5
uniprot id: A0A6J3DZU0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyltransferase family.
messages: Cleaves the gamma-glutamyl peptide bond of glutathione and glutathione conjugates.
messages: Membrane

219594:SLC2A8
gene id: 219594:SLC2A8
uniprot id: A0A6J3DZN1
names: Similarity
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.

219594:PSMD7
gene id: 219594:PSMD7
uniprot id: A0A6J3DMA7
names: Similarity
messages: Belongs to the peptidase M67A family.

219594:LOC116501318
gene id: 219594:LOC116501318
uniprot id: A0A6J3EMV5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

219594:KIT
gene id: 219594:KIT
uniprot id: A0A6J3CZJ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.
messages: Cell membrane
messages: Membrane

219594:ARL8A
gene id: 219594:ARL8A
uniprot id: A0A6J3EAY9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Arf family.
messages: Endosome membrane
messages: Late endosome membrane
messages: Lysosome membrane

219594:DLGAP1
gene id: 219594:DLGAP1
uniprot id: A0A6J3CFC6
uniprot id: A0A6J3CI05
uniprot id: A0A6J3CJW8
names: Similarity
messages: Belongs to the SAPAP family.

219594:CHPF
gene id: 219594:CHPF
uniprot id: A0A6J3D546
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chondroitin N-acetylgalactosaminyltransferase family.
messages: Golgi stack membrane
messages: Membrane

219594:RRN3
gene id: 219594:RRN3
uniprot id: A0A6J3DUD7
names: Similarity
messages: Belongs to the RRN3 family.

219594:LOC116497720
gene id: 219594:LOC116497720
uniprot id: A0A6J3E6R3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein arginine deiminase family.
messages: Cytoplasm

219594:LUC7L
gene id: 219594:LUC7L
uniprot id: A0A6J3DRI4
uniprot id: A0A6J3DVB4
names: Similarity
messages: Belongs to the Luc7 family.

219594:AGPAT4
gene id: 219594:AGPAT4
uniprot id: A0A6J3CRA1
uniprot id: A0A6J3CTI6
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.

219594:ATP2B1
gene id: 219594:ATP2B1
uniprot id: A0A6J3D1L7
uniprot id: A0A6J3D3Z8
uniprot id: A0A6J3D524
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIB subfamily.
messages: Catalyzes the hydrolysis of ATP coupled with the transport of calcium.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

219594:DUSP26
gene id: 219594:DUSP26
uniprot id: A0A6J3E9X5
uniprot id: A0A6J3EF84
names: Function
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.
messages: Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate.

219594:HEATR5B
gene id: 219594:HEATR5B
uniprot id: A0A6J3CSF2
names: Similarity
messages: Belongs to the HEATR5 family.

219594:LOC116501345
gene id: 219594:LOC116501345
uniprot id: A0A6J3ELK7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

219594:FOXE3
gene id: 219594:FOXE3
uniprot id: A0A6J3DGY7
names: Subcellular Location Annotation
messages: Nucleus

219594:LOC116491262
gene id: 219594:LOC116491262
uniprot id: A0A6J3DCF1
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:SSBP3
gene id: 219594:SSBP3
uniprot id: A0A6J3DCX7
uniprot id: A0A6J3DF54
names: Subcellular Location Annotation
messages: Nucleus

219594:LONP2
gene id: 219594:LONP2
uniprot id: A0A6J3DLA3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: ATP-dependent serine protease that mediates the selective degradation of misfolded and unassembled polypeptides in the peroxisomal matrix. Necessary for type 2 peroxisome targeting signal (PTS2)-containing protein processing and facilitates peroxisome matrix protein import.
messages: Belongs to the peptidase S16 family.
messages: Nucleus
messages: Peroxisome matrix

219594:LOC116499875
gene id: 219594:LOC116499875
uniprot id: A0A6J3EA93
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

219594:DGAT2
gene id: 219594:DGAT2
uniprot id: A0A6J3DP94
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the diacylglycerol acyltransferase family.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:SULF2
gene id: 219594:SULF2
uniprot id: A0A6J3DVQ0
names: Cofactor
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfatase family.
messages: Binds 1 Ca(2+) ion per subunit.
messages: Cell surface
messages: Endoplasmic reticulum
messages: Golgi stack
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

219594:LOC116491360
gene id: 219594:LOC116491360
uniprot id: A0A6J3D6T6
names: Caution
names: Similarity
messages: Belongs to the DMBT1 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:ACTA2
gene id: 219594:ACTA2
uniprot id: A0A6J3D7B9
names: Similarity
messages: Belongs to the actin family.

219594:MYO7B
gene id: 219594:MYO7B
uniprot id: A0A6J3DIW0
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.

219594:LOC116490867
gene id: 219594:LOC116490867
uniprot id: A0A6J3D7G9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

219594:ITGB1
gene id: 219594:ITGB1
uniprot id: A0A6J3CCL3
uniprot id: A0A6J3CE86
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin beta chain family.
messages: Cell membrane
messages: Membrane

219594:PROM1
gene id: 219594:PROM1
uniprot id: A0A6J3CVY3
uniprot id: A0A6J3CY88
uniprot id: A0A6J3CYK1
uniprot id: A0A6J3CYK7
uniprot id: A0A6J3D0U3
uniprot id: A0A6J3D0U7
uniprot id: A0A6J3D1Z7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prominin family.
messages: Membrane
messages: microvillus membrane

219594:KCNE4
gene id: 219594:KCNE4
uniprot id: A0A6J3DFH9
names: Similarity
messages: Belongs to the potassium channel KCNE family.

219594:OPN1SW
gene id: 219594:OPN1SW
uniprot id: A0A6J3DWP1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Opsin subfamily.
messages: Membrane

219594:ST6GALNAC1
gene id: 219594:ST6GALNAC1
uniprot id: A0A6J3DZI6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

219594:LOC116500140
gene id: 219594:LOC116500140
uniprot id: A0A6J3EFY9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

219594:SLC25A34
gene id: 219594:SLC25A34
uniprot id: A0A6J3E2Q8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

219594:LOC116488189
gene id: 219594:LOC116488189
uniprot id: A0A6J3CR11
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM47 family.
messages: Membrane

219594:PITHD1
gene id: 219594:PITHD1
uniprot id: A0A6J3E4W9
names: Similarity
messages: Belongs to the PITHD1 family.

219594:SLC45A2
gene id: 219594:SLC45A2
uniprot id: A0A6J3EK62
names: Subcellular Location Annotation
messages: Membrane

219594:ISX
gene id: 219594:ISX
uniprot id: A0A6J3ELG2
names: Subcellular Location Annotation
messages: Nucleus

219594:EMC3
gene id: 219594:EMC3
uniprot id: A0A6J3DJR6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EMC3 family.
messages: Component of the ER membrane protein complex (EMC).
messages: Membrane

219594:LOC116498587
gene id: 219594:LOC116498587
uniprot id: A0A6J3EBQ9
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Alax-L subfamily.

219594:LOC116492932
gene id: 219594:LOC116492932
uniprot id: A0A6J3DIC6
uniprot id: A0A6J3DKH7
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M20A family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Cytoplasm

219594:FGFR1OP2
gene id: 219594:FGFR1OP2
uniprot id: A0A6J3DJZ2
names: Similarity
messages: Belongs to the SIKE family.

219594:PAPPA2
gene id: 219594:PAPPA2
uniprot id: A0A6J3DFE5
names: Caution
names: Similarity
messages: Belongs to the peptidase M43B family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:LOC116501262
gene id: 219594:LOC116501262
uniprot id: A0A6J3EG18
uniprot id: A0A6J3ELD8
names: Similarity
messages: Belongs to the ARTD/PARP family.

219594:HSPA5
gene id: 219594:HSPA5
uniprot id: A0A6J3E3N3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heat shock protein 70 family.
messages: Endoplasmic reticulum lumen

219594:UNC5B
gene id: 219594:UNC5B
uniprot id: A0A6J3D6G4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the unc-5 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for netrin required for axon guidance. Mediates axon repulsion of neuronal growth cones in the developing nervous system upon ligand binding.

219594:GALNT10
gene id: 219594:GALNT10
uniprot id: A0A6J3DM07
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
messages: Golgi apparatus membrane
messages: Membrane

219594:CTBP1
gene id: 219594:CTBP1
uniprot id: A0A6J3CV20
uniprot id: A0A6J3CXD1
uniprot id: A0A6J3CXP8
uniprot id: A0A6J3D162
uniprot id: A0A6J3D167
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Nucleus

219594:RPS28
gene id: 219594:RPS28
uniprot id: A0A6J3ECE9
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS28 family.

219594:ASIC3
gene id: 219594:ASIC3
uniprot id: A0A6J3CLW0
names: Subcellular Location Annotation
messages: Membrane

219594:LOC116496131
gene id: 219594:LOC116496131
uniprot id: A0A6J3DU97
uniprot id: A0A6J3DYD3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:OSBPL5
gene id: 219594:OSBPL5
uniprot id: A0A6J3D470
names: Similarity
messages: Belongs to the OSBP family.

219594:PNKD
gene id: 219594:PNKD
uniprot id: A0A6J3D9H8
names: Similarity
messages: Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.

219594:MTCH2
gene id: 219594:MTCH2
uniprot id: A0A6J3D151
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

219594:SUSD4
gene id: 219594:SUSD4
uniprot id: A0A6J3CR43
uniprot id: A0A6J3CXA2
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:LOC116489384
gene id: 219594:LOC116489384
uniprot id: A0A6J3CZB8
names: Similarity
messages: Belongs to the globin family.

219594:LOC116501306
gene id: 219594:LOC116501306
uniprot id: A0A6J3ELD5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

219594:MKX
gene id: 219594:MKX
uniprot id: A0A6J3CLF6
uniprot id: A0A6J3CPP6
names: Subcellular Location Annotation
messages: Nucleus

219594:LOC116498198
gene id: 219594:LOC116498198
uniprot id: A0A6J3E8Y0
names: Subcellular Location Annotation
messages: Nucleus

219594:CAMK2D
gene id: 219594:CAMK2D
uniprot id: A0A6J3CVF9
uniprot id: A0A6J3CVG3
uniprot id: A0A6J3CVG8
uniprot id: A0A6J3CXT1
uniprot id: A0A6J3CXT7
uniprot id: A0A6J3CXU1
uniprot id: A0A6J3CY47
uniprot id: A0A6J3CY53
uniprot id: A0A6J3CY61
uniprot id: A0A6J3D0E6
uniprot id: A0A6J3D0F1
uniprot id: A0A6J3D1K1
uniprot id: A0A6J3D1K6
names: Similarity
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. CaMK subfamily.

219594:CNTNAP1
gene id: 219594:CNTNAP1
uniprot id: A0A6J3E4G8
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the neurexin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: paranodal septate junction

219594:XIAP
gene id: 219594:XIAP
uniprot id: A0A6J3DSX6
names: Similarity
messages: Belongs to the IAP family.

219594:NDUFB5
gene id: 219594:NDUFB5
uniprot id: A0A6J3DJ67
names: Function
names: Similarity
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFB5 subunit family.
messages: Complex I is composed of 45 different subunits.

219594:TCEA1
gene id: 219594:TCEA1
uniprot id: A0A6J3CM21
uniprot id: A0A6J3CNM0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TFS-II family.
messages: Necessary for efficient RNA polymerase II transcription elongation past template-encoded arresting sites.
messages: Necessary for efficient RNA polymerase II transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by S-II allows the resumption of elongation from the new 3'-terminus.
messages: Nucleus

219594:PPP1R13B
gene id: 219594:PPP1R13B
uniprot id: A0A6J3D0V3
uniprot id: A0A6J3D0Y1
uniprot id: A0A6J3D3C4
uniprot id: A0A6J3D4D1
names: Subcellular Location Annotation
messages: Nucleus

219594:LOC116492325
gene id: 219594:LOC116492325
uniprot id: A0A6J3DHJ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glypican family.
messages: Cell membrane
messages: Cell surface proteoglycan.

219594:XPOT
gene id: 219594:XPOT
uniprot id: A0A6J3DG59
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exportin family.
messages: Cytoplasm
messages: Nucleus
messages: tRNA nucleus export receptor which facilitates tRNA translocation across the nuclear pore complex.

219594:SNRPD3
gene id: 219594:SNRPD3
uniprot id: A0A6J3DZ15
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the snRNP core protein family.
messages: Nucleus
messages: cytosol

219594:MARVELD2
gene id: 219594:MARVELD2
uniprot id: A0A6J3ELB6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELL/occludin family.
messages: Cell membrane
messages: Membrane
messages: tight junction

219594:TRPM7
gene id: 219594:TRPM7
uniprot id: A0A6J3DMH1
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Binds 1 zinc ion per subunit.
messages: In the C-terminal section; belongs to the protein kinase superfamily. Alpha-type protein kinase family. ALPK subfamily.
messages: Membrane

219594:TM4SF18
gene id: 219594:TM4SF18
uniprot id: A0A6J3DFN3
uniprot id: A0A6J3DGW0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L6 tetraspanin family.
messages: Membrane

219594:PPP1R12B
gene id: 219594:PPP1R12B
uniprot id: A0A6J3E674
uniprot id: A0A6J3E678
uniprot id: A0A6J3E7N9
uniprot id: A0A6J3E7P4
uniprot id: A0A6J3EAQ4
uniprot id: A0A6J3EBA1
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: PP1 comprises a catalytic subunit, and one or several targeting or regulatory subunits.

219594:BCL2
gene id: 219594:BCL2
uniprot id: A0A6J3CL64
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Bcl-2 family.
messages: Cytoplasm
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Mitochondrion outer membrane
messages: Nucleus membrane

219594:MYO15B
gene id: 219594:MYO15B
uniprot id: A0A6J3E2S7
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.

219594:RECQL5
gene id: 219594:RECQL5
uniprot id: A0A6J3E1P5
names: Similarity
messages: Belongs to the helicase family. RecQ subfamily.

219594:SULT4A1
gene id: 219594:SULT4A1
uniprot id: A0A6J3CED4
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

219594:ZNF687
gene id: 219594:ZNF687
uniprot id: A0A6J3EBC8
names: Function
names: Subcellular Location Annotation
messages: May be involved in transcriptional regulation.
messages: Nucleus

219594:LOC116501299
gene id: 219594:LOC116501299
uniprot id: A0A6J3EHL5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

219594:SLC35A4
gene id: 219594:SLC35A4
uniprot id: A0A6J3DTY5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleotide-sugar transporter family. SLC35A subfamily.
messages: Golgi apparatus membrane
messages: Membrane

219594:SUCLG2
gene id: 219594:SUCLG2
uniprot id: A0A6J3DKG0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family. GTP-specific subunit beta subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: GTP-specific succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
messages: Heterodimer of an alpha and a beta subunit. The beta subunit determines specificity for GTP.
messages: Mitochondrion

219594:HSF4
gene id: 219594:HSF4
uniprot id: A0A6J3DJD3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HSF family.
messages: Nucleus

219594:VAMP4
gene id: 219594:VAMP4
uniprot id: A0A6J3DGJ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptobrevin family.
messages: Membrane

219594:IWS1
gene id: 219594:IWS1
uniprot id: A0A6J3DBT4
uniprot id: A0A6J3DHB6
names: Subcellular Location Annotation
messages: Nucleus

219594:CTPS1
gene id: 219594:CTPS1
uniprot id: A0A6J3E3M6
names: Function
names: Similarity
messages: Belongs to the CTP synthase family.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.

219594:LOC116498329
gene id: 219594:LOC116498329
uniprot id: A0A6J3E989
names: Similarity
messages: Belongs to the protein kinase superfamily.

219594:HDAC2
gene id: 219594:HDAC2
uniprot id: A0A6J3CRK1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone deacetylase family. HD Type 1 subfamily.
messages: Nucleus

219594:APH1A
gene id: 219594:APH1A
uniprot id: A0A6J3EEB0
uniprot id: A0A6J3EEP1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the APH-1 family.
messages: Component of the gamma-secretase complex.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Potential subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral proteins such as Notch receptors.

219594:P2RY4
gene id: 219594:P2RY4
uniprot id: A0A6J3DL96
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

219594:ART4
gene id: 219594:ART4
uniprot id: A0A6J3ERH5
names: Similarity
messages: Belongs to the Arg-specific ADP-ribosyltransferase family.

219594:KCNJ13
gene id: 219594:KCNJ13
uniprot id: A0A6J3DHI2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family.
messages: Membrane

219594:LRP1B
gene id: 219594:LRP1B
uniprot id: A0A6J3D8W8
names: Caution
names: Similarity
messages: Belongs to the LDLR family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:PARG
gene id: 219594:PARG
uniprot id: A0A6J3D6A3
uniprot id: A0A6J3DC76
names: Similarity
messages: Belongs to the poly(ADP-ribose) glycohydrolase family.

219594:LOC116491258
gene id: 219594:LOC116491258
uniprot id: A0A6J3DCE6
names: Similarity
messages: Belongs to the DEAD box helicase family. DDX21/DDX50 subfamily.

219594:LOC116498866
gene id: 219594:LOC116498866
uniprot id: A0A6J3EBF4
names: Similarity
messages: Belongs to the glycosyl hydrolase 18 family. Chitinase class II subfamily.

219594:LOC116500058
gene id: 219594:LOC116500058
uniprot id: A0A6J3ECA2
names: Similarity
messages: Belongs to the ATG8 family.

219594:ANKZF1
gene id: 219594:ANKZF1
uniprot id: A0A6J3D435
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ANKZF1/VMS1 family.
messages: Cytoplasm

219594:PSPH
gene id: 219594:PSPH
uniprot id: A0A6J3E587
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

219594:ATG16L1
gene id: 219594:ATG16L1
uniprot id: A0A6J3DEG1
uniprot id: A0A6J3DFM4
uniprot id: A0A6J3DHB9
uniprot id: A0A6J3DHW5
names: Similarity
messages: Belongs to the WD repeat ATG16 family.

219594:TMEM245
gene id: 219594:TMEM245
uniprot id: A0A6J3CHV2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

219594:ABCG8
gene id: 219594:ABCG8
uniprot id: A0A6J3CS30
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCG family. Eye pigment precursor importer (TC 3.A.1.204) subfamily.
messages: Membrane

219594:EXOC3L4
gene id: 219594:EXOC3L4
uniprot id: A0A6J3D2D4
names: Similarity
messages: Belongs to the SEC6 family.

219594:DPY30
gene id: 219594:DPY30
uniprot id: A0A6J3CTB7
names: Similarity
messages: Belongs to the dpy-30 family.

219594:LOC116486605
gene id: 219594:LOC116486605
uniprot id: A0A6J3CLE0
names: Similarity
names: Subunit
messages: Belongs to the avian keratin family.
messages: The avian keratins (F-ker, S-ker, C-ker and B-ker) are a complex mixture of very similar polypeptides.

219594:IVD
gene id: 219594:IVD
uniprot id: A0A6J3D767
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

219594:MPP4
gene id: 219594:MPP4
uniprot id: A0A6J3D3F7
names: Similarity
messages: Belongs to the MAGUK family.

219594:PIWIL1
gene id: 219594:PIWIL1
uniprot id: A0A6J3DZ90
names: Similarity
messages: Belongs to the argonaute family.

219594:DDX4
gene id: 219594:DDX4
uniprot id: A0A6J3EE28
names: Similarity
messages: Belongs to the DEAD box helicase family.

219594:PIEZO1
gene id: 219594:PIEZO1
uniprot id: A0A6J3DPG2
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PIEZO (TC 1.A.75) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

219594:FAM133B
gene id: 219594:FAM133B
uniprot id: A0A6J3CGD3
names: Similarity
messages: Belongs to the FAM133 family.

219594:KIF13B
gene id: 219594:KIF13B
uniprot id: A0A6J3CKB8
uniprot id: A0A6J3CRA0
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

219594:MYCBP2
gene id: 219594:MYCBP2
uniprot id: A0A6J3CKN6
uniprot id: A0A6J3CM47
uniprot id: A0A6J3CMB9
uniprot id: A0A6J3CN90
uniprot id: A0A6J3CQI0
uniprot id: A0A6J3CQK2
uniprot id: A0A6J3CQN8
uniprot id: A0A6J3CQP8
uniprot id: A0A6J3CRL3
uniprot id: A0A6J3CRN6
uniprot id: A0A6J3CRP7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RING-Cys relay (RCR) family.
messages: axon

219594:TSPAN1
gene id: 219594:TSPAN1
uniprot id: A0A6J3DE22
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

219594:SEPTIN10
gene id: 219594:SEPTIN10
uniprot id: A0A6J3CPG8
uniprot id: A0A6J3CPH9
uniprot id: A0A6J3CQA8
uniprot id: A0A6J3CSJ0
uniprot id: A0A6J3CSK0
uniprot id: A0A6J3CTL6
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.

219594:ND3
gene id: 219594:ND3
uniprot id: A0A068L9B6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 3 family.
messages: Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor. Essential for the catalytic activity of complex I.
messages: Mitochondrion membrane

219594:GATAD1
gene id: 219594:GATAD1
uniprot id: A0A6J3CG94
names: Subcellular Location Annotation
messages: Nucleus

219594:SLC25A4
gene id: 219594:SLC25A4
uniprot id: A0A6J3CZB2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Catalyzes the exchange of ADP and ATP across the membrane.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Monomer.

219594:GUSB
gene id: 219594:GUSB
uniprot id: A0A6J3DZV7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 2 family.
messages: Lysosome

219594:LOC116500261
gene id: 219594:LOC116500261
uniprot id: A0A6J3ECZ5
uniprot id: A0A6J3EGN9
uniprot id: A0A6J3EI95
names: Similarity
messages: Belongs to the MHC class I family.

219594:LOC116499364
gene id: 219594:LOC116499364
uniprot id: A0A6J3EFA1
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:LOC116497305
gene id: 219594:LOC116497305
uniprot id: A0A6J3E431
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

219594:POPDC2
gene id: 219594:POPDC2
uniprot id: A0A6J3EII9
uniprot id: A0A6J3ENQ7
names: Similarity
messages: Belongs to the popeye family.

219594:DMRT1
gene id: 219594:DMRT1
uniprot id: A0A6J3EE53
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DMRT family.
messages: Nucleus

219594:HDAC3
gene id: 219594:HDAC3
uniprot id: A0A6J3DS85
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone deacetylase family. HD Type 1 subfamily.
messages: Nucleus

219594:SCN3B
gene id: 219594:SCN3B
uniprot id: A0A6J3E6R0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium channel auxiliary subunit SCN3B (TC 8.A.17) family.
messages: Membrane
messages: Modulates channel gating kinetics. Causes unique persistent sodium currents. Inactivates the sodium channel opening more slowly than the subunit beta-1. Its association with NFASC may target the sodium channels to the nodes of Ranvier of developing axons and retain these channels at the nodes in mature myelinated axons.

219594:SH3GL2
gene id: 219594:SH3GL2
uniprot id: A0A6J3EKD0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endophilin family.
messages: Membrane

219594:RGMA
gene id: 219594:RGMA
uniprot id: A0A6J3DLN5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the repulsive guidance molecule (RGM) family.
messages: Cell membrane
messages: Membrane

219594:TOMM7
gene id: 219594:TOMM7
uniprot id: A0A6J3CQC8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Tom7 family.
messages: Membrane
messages: Mitochondrion outer membrane

219594:FDPS
gene id: 219594:FDPS
uniprot id: A0A6J3EE30
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

219594:TPD52L1
gene id: 219594:TPD52L1
uniprot id: A0A6J3CNM5
uniprot id: A0A6J3CQK9
uniprot id: A0A6J3CRA9
uniprot id: A0A6J3CTJ9
names: Similarity
messages: Belongs to the TPD52 family.

219594:USH2A
gene id: 219594:USH2A
uniprot id: A0A6J3CQS8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:HNF4G
gene id: 219594:HNF4G
uniprot id: A0A6J3CMD6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

219594:WSCD2
gene id: 219594:WSCD2
uniprot id: A0A6J3DX56
names: Function
names: Similarity
messages: Belongs to the WSCD family.
messages: Sialate:O-sulfotransferase which catalyzes 8-O-sulfation at the Sia-glycan level using 3'-phosphoadenosine 5'-phosphosulfate (PAPS) as a donor, forming 8-O-sulfated Sia (Sia8S)-glycans.

219594:LOC116498288
gene id: 219594:LOC116498288
uniprot id: A0A6J3E8I7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

219594:LOC116500993
gene id: 219594:LOC116500993
uniprot id: A0A6J3EJV8
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M1 family.
messages: Binds 1 zinc ion per subunit.

219594:LOC116500368
gene id: 219594:LOC116500368
uniprot id: A0A6J3EGY3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the insulin family.
messages: Secreted

219594:EXOG
gene id: 219594:EXOG
uniprot id: A0A6J3CLD7
names: Similarity
messages: Belongs to the DNA/RNA non-specific endonuclease family.

219594:DGKH
gene id: 219594:DGKH
uniprot id: A0A6J3D3E7
uniprot id: A0A6J3D3I0
uniprot id: A0A6J3D8M9
uniprot id: A0A6J3D8Q5
uniprot id: A0A6J3D9B7
names: Similarity
messages: Belongs to the eukaryotic diacylglycerol kinase family.

219594:LHFPL3
gene id: 219594:LHFPL3
uniprot id: A0A6J3CBS8
uniprot id: A0A6J3CG92
names: Subcellular Location Annotation
messages: Membrane

219594:LOC116490589
gene id: 219594:LOC116490589
uniprot id: A0A6J3D8N5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:LOC116491328
gene id: 219594:LOC116491328
uniprot id: A0A6J3D6P6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COX15/CtaA family.
messages: Membrane

219594:JAKMIP1
gene id: 219594:JAKMIP1
uniprot id: A0A6J3CUK4
uniprot id: A0A6J3CWV9
uniprot id: A0A6J3D0Q0
names: Similarity
messages: Belongs to the JAKMIP family.

219594:PABPC4
gene id: 219594:PABPC4
uniprot id: A0A6J3E4H1
uniprot id: A0A6J3E815
uniprot id: A0A6J3E9F9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyadenylate-binding protein type-1 family.
messages: Binds the poly(A) tail of mRNA.
messages: Cytoplasm

219594:RPL32
gene id: 219594:RPL32
uniprot id: A0A6J3DEM6
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL32 family.

219594:LOC116490160
gene id: 219594:LOC116490160
uniprot id: A0A6J3D3S9
names: Similarity
messages: Belongs to the peptidase A1 family.

219594:FGD2
gene id: 219594:FGD2
uniprot id: A0A6J3E854
uniprot id: A0A6J3EB61
uniprot id: A0A6J3EDA8
names: Subcellular Location Annotation
messages: cytoskeleton

219594:KIF26A
gene id: 219594:KIF26A
uniprot id: A0A6J3CYU8
uniprot id: A0A6J3D4V2
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

219594:VENTX
gene id: 219594:VENTX
uniprot id: A0A6J3DA10
names: Subcellular Location Annotation
messages: Nucleus

219594:CRY1
gene id: 219594:CRY1
uniprot id: A0A6J3E2M6
names: Cofactor
names: Similarity
messages: Belongs to the DNA photolyase class-1 family.
messages: Binds 1 FAD per subunit.

219594:C1D
gene id: 219594:C1D
uniprot id: A0A6J3CQW8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the C1D family.
messages: Cytoplasm
messages: Monomer and homodimer.
messages: Plays a role in the recruitment of the exosome to pre-rRNA to mediate the 3'-5' end processing of the 5.8S rRNA.
messages: nucleolus

219594:LYRM9
gene id: 219594:LYRM9
uniprot id: A0A6J3DYX1
uniprot id: A0A6J3E366
names: Similarity
messages: Belongs to the complex I LYR family. LYRM9 subfamily.

219594:SNAP47
gene id: 219594:SNAP47
uniprot id: A0A6J3CL97
names: Similarity
messages: Belongs to the SVAP1 family.

219594:LOC116493519
gene id: 219594:LOC116493519
uniprot id: A0A6J3DMV1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

219594:CDK5
gene id: 219594:CDK5
uniprot id: A0A6J3CFK5
uniprot id: A0A6J3CH74
names: Similarity
messages: Belongs to the protein kinase superfamily.

219594:LOC116493873
gene id: 219594:LOC116493873
uniprot id: A0A6J3DQ10
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 1 family. Gal/GlcNAc/GalNAc subfamily.
messages: Membrane

219594:PARP10
gene id: 219594:PARP10
uniprot id: A0A6J3CF86
names: Similarity
messages: Belongs to the ARTD/PARP family.

219594:ANO5
gene id: 219594:ANO5
uniprot id: A0A6J3CX45
uniprot id: A0A6J3CZE5
uniprot id: A0A6J3CZN8
uniprot id: A0A6J3D322
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anoctamin family.
messages: Cell membrane
messages: Membrane

219594:TMEM87A
gene id: 219594:TMEM87A
uniprot id: A0A6J3D2R8
names: Subcellular Location Annotation
messages: Membrane

219594:LOC116489844
gene id: 219594:LOC116489844
uniprot id: A0A6J3D5H4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protease inhibitor I39 (alpha-2-macroglobulin) family.
messages: Secreted

219594:XKR7
gene id: 219594:XKR7
uniprot id: A0A6J3DU88
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the XK family.
messages: Membrane

219594:GPC6
gene id: 219594:GPC6
uniprot id: A0A6J3E914
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glypican family.
messages: Cell membrane
messages: Cell surface proteoglycan.

219594:PTS
gene id: 219594:PTS
uniprot id: A0A6J3E6M5
names: Function
names: Similarity
messages: Belongs to the PTPS family.
messages: Involved in the biosynthesis of tetrahydrobiopterin, an essential cofactor of aromatic amino acid hydroxylases. Catalyzes the transformation of 7,8-dihydroneopterin triphosphate into 6-pyruvoyl tetrahydropterin.

219594:TRHR
gene id: 219594:TRHR
uniprot id: A0A6J3CJH1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for thyrotropin-releasing hormone (TRH). Upon ligand binding, this G-protein-coupled receptor triggers activation of the phosphatidylinositol (IP3)-calcium-protein kinase C (PKC) pathway.

219594:HSPA8
gene id: 219594:HSPA8
uniprot id: A0A6J3E6E8
names: Similarity
messages: Belongs to the heat shock protein 70 family.

219594:SLC6A15
gene id: 219594:SLC6A15
uniprot id: A0A6J3CWB3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. SLC6A15 subfamily.
messages: Membrane

219594:RPL22L1
gene id: 219594:RPL22L1
uniprot id: A0A6J3DJ74
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL22 family.

219594:MAP3K9
gene id: 219594:MAP3K9
uniprot id: A0A6J3D5U7
names: Activity Regulation
names: Similarity
names: Subunit
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.
messages: Homodimer.
messages: Homodimerization via the leucine zipper domains is required for autophosphorylation.

219594:UTP18
gene id: 219594:UTP18
uniprot id: A0A6J3E0R4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat UTP18 family.
messages: nucleolus

219594:MAPK8
gene id: 219594:MAPK8
uniprot id: A0A6J3D9E2
uniprot id: A0A6J3DBL3
uniprot id: A0A6J3DC22
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MAP kinase subfamily.
messages: Cytoplasm
messages: Responds to activation by environmental stress and pro-inflammatory cytokines by phosphorylating a number of transcription factors, and thus regulates transcriptional activity.

219594:WASHC5
gene id: 219594:WASHC5
uniprot id: A0A6J3CHW6
names: Similarity
messages: Belongs to the strumpellin family.

219594:INTS9
gene id: 219594:INTS9
uniprot id: A0A6J3CN79
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. INTS9 subfamily.
messages: Nucleus

219594:CPNE9
gene id: 219594:CPNE9
uniprot id: A0A6J3DLN3
names: Similarity
messages: Belongs to the copine family.

219594:ATP9A
gene id: 219594:ATP9A
uniprot id: A0A6J3DX99
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.
messages: Membrane

219594:HENMT1
gene id: 219594:HENMT1
uniprot id: A0A6J3DEU4
names: Similarity
messages: Belongs to the methyltransferase superfamily. HEN1 family.

219594:MESD
gene id: 219594:MESD
uniprot id: A0A6J3DJ66
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MESD family.
messages: Endoplasmic reticulum

219594:LOC116493608
gene id: 219594:LOC116493608
uniprot id: A0A6J3DN81
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZP domain family. ZPC subfamily.
messages: Cell membrane
messages: Component of the zona pellucida, an extracellular matrix surrounding oocytes which mediates sperm binding, induction of the acrosome reaction and prevents post-fertilization polyspermy. The zona pellucida is composed of 3 to 4 glycoproteins, ZP1, ZP2, ZP3, and ZP4. ZP3 is essential for sperm binding and zona matrix formation.
messages: Proteolytically cleaved before the transmembrane segment to yield the secreted ectodomain incorporated in the zona pellucida.
messages: The ZP domain is involved in the polymerization of the ZP proteins to form the zona pellucida.
messages: Zona pellucida

219594:GAPVD1
gene id: 219594:GAPVD1
uniprot id: A0A6J3DXE0
uniprot id: A0A6J3DZ52
uniprot id: A0A6J3E2D9
uniprot id: A0A6J3E3H2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GAPVD1 family.
messages: Membrane

219594:CD63
gene id: 219594:CD63
uniprot id: A0A6J3EFH5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

219594:TOMM20
gene id: 219594:TOMM20
uniprot id: A0A6J3CNS1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Tom20 family.
messages: Membrane
messages: Mitochondrion outer membrane

219594:MTG1
gene id: 219594:MTG1
uniprot id: A0A6J3DCG1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily.
messages: Mitochondrion inner membrane
messages: Plays a role in the regulation of the mitochondrial ribosome assembly and of translational activity. Displays mitochondrial GTPase activity.

219594:AREG
gene id: 219594:AREG
uniprot id: A0A6J3CV68
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:DST
gene id: 219594:DST
uniprot id: A0A6J3CLH8
uniprot id: A0A6J3CLI3
uniprot id: A0A6J3CLI8
uniprot id: A0A6J3CN54
uniprot id: A0A6J3CN59
uniprot id: A0A6J3CN65
uniprot id: A0A6J3CP53
uniprot id: A0A6J3CP58
uniprot id: A0A6J3CRD9
uniprot id: A0A6J3CRE7
uniprot id: A0A6J3CSF5
uniprot id: A0A6J3CSF9
uniprot id: A0A6J3CSG5
names: Subcellular Location Annotation
messages: cytoskeleton

219594:ZP4
gene id: 219594:ZP4
uniprot id: A0A6J3D6K1
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZP domain family. ZPB subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Zona pellucida

219594:DVL1
gene id: 219594:DVL1
uniprot id: A0A6J3E0Q1
uniprot id: A0A6J3E4X6
uniprot id: A0A6J3E5Q2
names: Similarity
messages: Belongs to the DSH family.

219594:PROK2
gene id: 219594:PROK2
uniprot id: A0A6J3DJK6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AVIT (prokineticin) family.
messages: Secreted

219594:SPRTN
gene id: 219594:SPRTN
uniprot id: A0A6J3CS47
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Spartan family.
messages: Chromosome
messages: Nucleus

219594:NIT2
gene id: 219594:NIT2
uniprot id: A0A6J3CHM4
uniprot id: A0A6J3CKB1
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.

219594:LOC116485389
gene id: 219594:LOC116485389
uniprot id: A0A6J3CC57
names: Similarity
names: Subunit
messages: Belongs to the avian keratin family.
messages: The avian keratins (F-ker, S-ker, C-ker and B-ker) are a complex mixture of very similar polypeptides.

219594:PRKAR2B
gene id: 219594:PRKAR2B
uniprot id: A0A6J3DUE6
uniprot id: A0A6J3DW91
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cAMP-dependent kinase regulatory chain family.
messages: Cell membrane
messages: Membrane

219594:DUSP12
gene id: 219594:DUSP12
uniprot id: A0A6J3CTC0
uniprot id: A0A6J3CW28
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.

219594:HOXC8
gene id: 219594:HOXC8
uniprot id: A0A6J3EFB7
names: Subcellular Location Annotation
messages: Nucleus

219594:NDFIP2
gene id: 219594:NDFIP2
uniprot id: A0A6J3CF53
uniprot id: A0A6J3CF64
uniprot id: A0A6J3CGV3
names: Subcellular Location Annotation
messages: Membrane

219594:KIAA2013
gene id: 219594:KIAA2013
uniprot id: A0A6J3E314
names: Subcellular Location Annotation
messages: Membrane

219594:MYO19
gene id: 219594:MYO19
uniprot id: A0A6J3DZ94
uniprot id: A0A6J3E0U6
uniprot id: A0A6J3E3I9
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.

219594:SHARPIN
gene id: 219594:SHARPIN
uniprot id: A0A6J3CEI3
names: Similarity
messages: Belongs to the RBR family.

219594:NTRK2
gene id: 219594:NTRK2
uniprot id: A0A6J3EBV8
uniprot id: A0A6J3ED72
uniprot id: A0A6J3EGW7
uniprot id: A0A6J3EIG6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. Insulin receptor subfamily.
messages: Membrane

219594:NXT2
gene id: 219594:NXT2
uniprot id: A0A6J3DS92
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Has a role in nuclear-cytoplasmic transport of proteins and mRNAs.
messages: Nucleus

219594:CRYGS
gene id: 219594:CRYGS
uniprot id: A0A6J3DD81
names: Similarity
names: Subunit
messages: Belongs to the beta/gamma-crystallin family.
messages: Homo/heterodimer, or complexes of higher-order. The structure of beta-crystallin oligomers seems to be stabilized through interactions between the N-terminal arms.

219594:RGS7BP
gene id: 219594:RGS7BP
uniprot id: A0A6J3EEA0
uniprot id: A0A6J3EHS7
uniprot id: A0A6J3EJQ2
names: Similarity
messages: Belongs to the RGS7BP/RGS9BP family.

219594:LOC116501302
gene id: 219594:LOC116501302
uniprot id: A0A6J3ELG8
names: Subcellular Location Annotation
messages: Membrane

219594:MAPK8IP2
gene id: 219594:MAPK8IP2
uniprot id: A0A6J3E1J9
uniprot id: A0A6J3E4A5
uniprot id: A0A6J3E691
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the JIP scaffold family.
messages: Cytoplasm

219594:LOC116501371
gene id: 219594:LOC116501371
uniprot id: A0A6J3EHT6
uniprot id: A0A6J3ELJ3
uniprot id: A0A6J3EN04
names: Subcellular Location Annotation
messages: Nucleus

219594:SUZ12
gene id: 219594:SUZ12
uniprot id: A0A6J3DZL4
names: Similarity
messages: Belongs to the VEFS (VRN2-EMF2-FIS2-SU(Z)12) family.

219594:RPS6KA5
gene id: 219594:RPS6KA5
uniprot id: A0A6J3D0T0
uniprot id: A0A6J3D395
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily.

219594:MYOD1
gene id: 219594:MYOD1
uniprot id: A0A6J3D3G9
names: Subcellular Location Annotation
names: Subunit
messages: Efficient DNA binding requires dimerization with another bHLH protein.
messages: Nucleus

219594:GORASP1
gene id: 219594:GORASP1
uniprot id: A0A6J3CJ54
names: Similarity
messages: Belongs to the GORASP family.

219594:CNKSR2
gene id: 219594:CNKSR2
uniprot id: A0A6J3E3B7
uniprot id: A0A6J3E4I9
uniprot id: A0A6J3E4N6
uniprot id: A0A6J3E7K0
uniprot id: A0A6J3E7L6
uniprot id: A0A6J3E863
uniprot id: A0A6J3E9J7
uniprot id: A0A6J3E9P2
names: Similarity
messages: Belongs to the CNKSR family.

219594:MAP1LC3B
gene id: 219594:MAP1LC3B
uniprot id: A0A6J3DLS9
names: Similarity
messages: Belongs to the ATG8 family.

219594:ERI1
gene id: 219594:ERI1
uniprot id: A0A6J3D0P2
names: Subcellular Location Annotation
messages: Cytoplasm

219594:MRPS6
gene id: 219594:MRPS6
uniprot id: A0A6J3CM05
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.

219594:LOC116492469
gene id: 219594:LOC116492469
uniprot id: A0A6J3DIF6
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

219594:OTC
gene id: 219594:OTC
uniprot id: A0A6J3CFB3
names: Similarity
names: Subunit
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily.
messages: Homotrimer.

219594:RPL7
gene id: 219594:RPL7
uniprot id: A0A6J3CN46
names: Similarity
messages: Belongs to the universal ribosomal protein uL30 family.

219594:HS3ST6
gene id: 219594:HS3ST6
uniprot id: A0A6J3DUR8
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

219594:AP1S3
gene id: 219594:AP1S3
uniprot id: A0A6J3DEI6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adaptor complexes small subunit family.
messages: Cytoplasmic vesicle membrane
messages: Golgi apparatus
messages: clathrin-coated pit

219594:PRKAR1B
gene id: 219594:PRKAR1B
uniprot id: A0A6J3DTR1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cAMP-dependent kinase regulatory chain family.
messages: Cell membrane
messages: Membrane

219594:USP3
gene id: 219594:USP3
uniprot id: A0A6J3DJ04
uniprot id: A0A6J3DLV9
uniprot id: A0A6J3DMC8
names: Similarity
messages: Belongs to the peptidase C19 family.

219594:RPL31
gene id: 219594:RPL31
uniprot id: A0A6J3EJC9
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eL31 family.
messages: Component of the large ribosomal subunit.

219594:LOC116500327
gene id: 219594:LOC116500327
uniprot id: A0A6J3EGT8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

219594:MAGI3
gene id: 219594:MAGI3
uniprot id: A0A6J3E6G4
uniprot id: A0A6J3EBI8
names: Subcellular Location Annotation
messages: Membrane

219594:SIX6
gene id: 219594:SIX6
uniprot id: A0A6J3D3W6
names: Subcellular Location Annotation
messages: Nucleus

219594:TMEM97
gene id: 219594:TMEM97
uniprot id: A0A6J3E569
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM97/sigma-2 receptor family.
messages: Endoplasmic reticulum membrane
messages: Intracellular orphan receptor that binds numerous drugs and which is highly expressed in various proliferating cells. Corresponds to the sigma-2 receptor, which is thought to play important role in regulating cell survival, morphology and differentiation. May play a role as a regulator of cellular cholesterol homeostasis. May function as sterol isomerase. May alter the activity of some cytochrome P450 proteins.
messages: Membrane
messages: Nucleus membrane
messages: Rough endoplasmic reticulum membrane

219594:GALNT14
gene id: 219594:GALNT14
uniprot id: A0A6J3CMF8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
messages: Golgi apparatus membrane
messages: Membrane

219594:XPNPEP2
gene id: 219594:XPNPEP2
uniprot id: A0A6J3DNS3
names: Similarity
messages: Belongs to the peptidase M24B family.

219594:C6H2orf88
gene id: 219594:C6H2orf88
uniprot id: A0A6J3D2T2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small membrane AKAP family.
messages: Cell membrane
messages: Membrane

219594:AMD1
gene id: 219594:AMD1
uniprot id: A0A6J3CQK0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the eukaryotic AdoMetDC family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Essential for biosynthesis of the polyamines spermidine and spermine. Promotes maintenance and self-renewal of embryonic stem cells, by maintaining spermine levels.

219594:MAB21L1
gene id: 219594:MAB21L1
uniprot id: A0A6J3D9Y4
names: Similarity
messages: Belongs to the mab-21 family.

219594:LOC116485641
gene id: 219594:LOC116485641
uniprot id: A0A6J3CG29
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion.
messages: desmosome

219594:NAALADL2
gene id: 219594:NAALADL2
uniprot id: A0A6J3DI12
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M28 family. M28B subfamily.
messages: Membrane

219594:LOC116489921
gene id: 219594:LOC116489921
uniprot id: A0A6J3D4S2
names: Domain
names: Subcellular Location Annotation
messages: The N-terminal C2 domain associates with lipid membranes upon calcium binding.
messages: cytosol

219594:RHCE
gene id: 219594:RHCE
uniprot id: A0A6J3E4B9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonium transporter (TC 2.A.49) family. Rh subfamily.
messages: Membrane

219594:LOC116490165
gene id: 219594:LOC116490165
uniprot id: A0A6J3D628
uniprot id: A0A6J3D6Z4
names: Subcellular Location Annotation
messages: Membrane

219594:FGF22
gene id: 219594:FGF22
uniprot id: A0A6J3ED12
names: Similarity
messages: Belongs to the heparin-binding growth factors family.

219594:BAK1
gene id: 219594:BAK1
uniprot id: A0A6J3ED09
names: Similarity
messages: Belongs to the Bcl-2 family.

219594:GCGR
gene id: 219594:GCGR
uniprot id: A0A6J3DW71
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

219594:LOC116501449
gene id: 219594:LOC116501449
uniprot id: A0A6J3ENE0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

219594:HSPG2
gene id: 219594:HSPG2
uniprot id: A0A6J3E0K9
uniprot id: A0A6J3E0L4
uniprot id: A0A6J3E1Z2
uniprot id: A0A6J3E1Z7
uniprot id: A0A6J3E4T3
uniprot id: A0A6J3E5L0
uniprot id: A0A6J3E6N9
uniprot id: A0A6J3E6P3
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: basement membrane

219594:ALDH6A1
gene id: 219594:ALDH6A1
uniprot id: A0A6J3D3S7
names: Function
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.
messages: Plays a role in valine and pyrimidine metabolism. Binds fatty acyl-CoA.

219594:GRIN2A
gene id: 219594:GRIN2A
uniprot id: A0A6J3DP61
uniprot id: A0A6J3DUF8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Receptor for glutamate that functions as a ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system.
messages: Synaptic cell membrane

219594:TRUB1
gene id: 219594:TRUB1
uniprot id: A0A6J3DCA5
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family.

219594:LOC116487538
gene id: 219594:LOC116487538
uniprot id: A0A6J3CN10
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. Very large inducible GTPase (VLIG) family.
messages: Nucleus

219594:GLIS2
gene id: 219594:GLIS2
uniprot id: A0A6J3DU03
names: Similarity
messages: Belongs to the GLI C2H2-type zinc-finger protein family.

219594:MMAB
gene id: 219594:MMAB
uniprot id: A0A6J3E075
names: Similarity
messages: Belongs to the Cob(I)alamin adenosyltransferase family.

219594:LOC116499716
gene id: 219594:LOC116499716
uniprot id: A0A6J3EB72
uniprot id: A0A6J3EEU7
uniprot id: A0A6J3EGH9
names: Similarity
names: Subunit
messages: Belongs to the avian keratin family.
messages: The avian keratins (F-ker, S-ker, C-ker and B-ker) are a complex mixture of very similar polypeptides.

219594:SLC25A21
gene id: 219594:SLC25A21
uniprot id: A0A6J3CZ98
uniprot id: A0A6J3D1I5
uniprot id: A0A6J3D2M7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

219594:RPS6
gene id: 219594:RPS6
uniprot id: A0A6J3EK38
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS6 family.

219594:SBK1
gene id: 219594:SBK1
uniprot id: A0A6J3DQT0
uniprot id: A0A6J3DV60
uniprot id: A0A6J3DW14
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
messages: Cytoplasm

219594:CHRM4
gene id: 219594:CHRM4
uniprot id: A0A6J3D4H5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Muscarinic acetylcholine receptor subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane
messages: The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins.

219594:CNPY2
gene id: 219594:CNPY2
uniprot id: A0A6J3EFI8
names: Similarity
messages: Belongs to the canopy family.

219594:APOA1
gene id: 219594:APOA1
uniprot id: A0A6J3E771
names: Similarity
messages: Belongs to the apolipoprotein A1/A4/E family.

219594:MVK
gene id: 219594:MVK
uniprot id: A0A6J3E0U4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. Mevalonate kinase subfamily.
messages: Catalyzes the phosphorylation of mevalonate to mevalonate 5-phosphate, a key step in isoprenoid and cholesterol biosynthesis.
messages: Cytoplasm
messages: Nucleus

219594:FOXS1
gene id: 219594:FOXS1
uniprot id: A0A6J3DUB6
names: Subcellular Location Annotation
messages: Nucleus

219594:PARVG
gene id: 219594:PARVG
uniprot id: A0A6J3EMY0
uniprot id: A0A6J3EPB5
names: Similarity
messages: Belongs to the parvin family.

219594:AQP11
gene id: 219594:AQP11
uniprot id: A0A6J3EID6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family. AQP11/AQP12 subfamily.
messages: Membrane

219594:PPIL3
gene id: 219594:PPIL3
uniprot id: A0A6J3D7C3
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

219594:CFI
gene id: 219594:CFI
uniprot id: A0A6J3CVC3
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

219594:TECPR1
gene id: 219594:TECPR1
uniprot id: A0A6J3DVV7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TECPR1 family.
messages: Lysosome membrane
messages: autophagosome membrane

219594:CSTF1
gene id: 219594:CSTF1
uniprot id: A0A6J3DXV8
names: Subcellular Location Annotation
messages: Nucleus

219594:CDT1
gene id: 219594:CDT1
uniprot id: A0A6J3DPP0
names: Similarity
messages: Belongs to the Cdt1 family.

219594:POU4F3
gene id: 219594:POU4F3
uniprot id: A0A6J3DT28
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the POU transcription factor family.
messages: Nucleus

219594:SAP30L
gene id: 219594:SAP30L
uniprot id: A0A6J3DTN9
names: Similarity
messages: Belongs to the SAP30 family.

219594:SLC37A4
gene id: 219594:SLC37A4
uniprot id: A0A6J3E2B9
uniprot id: A0A6J3E7B5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Organophosphate:Pi antiporter (OPA) (TC 2.A.1.4) family.
messages: Membrane

219594:TPM1
gene id: 219594:TPM1
uniprot id: A0A6J3DFY0
uniprot id: A0A6J3DFY5
uniprot id: A0A6J3DFZ2
uniprot id: A0A6J3DFZ7
uniprot id: A0A6J3DIL6
uniprot id: A0A6J3DIM6
uniprot id: A0A6J3DIN2
uniprot id: A0A6J3DJX3
uniprot id: A0A6J3DJX6
uniprot id: A0A6J3DJY0
uniprot id: A0A6J3DLI2
uniprot id: A0A6J3DLI7
uniprot id: A0A6J3DLI9
uniprot id: A0A6J3DLJ4
uniprot id: A0A6J3DM00
uniprot id: A0A6J3DM04
uniprot id: A0A6J3DM08
uniprot id: A0A6J3DM12
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tropomyosin family.
messages: cytoskeleton

219594:CD99L2
gene id: 219594:CD99L2
uniprot id: A0A6J3DNU1
names: Similarity
messages: Belongs to the CD99 family.

219594:MASP2
gene id: 219594:MASP2
uniprot id: A0A6J3E6U7
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:LOC116491304
gene id: 219594:LOC116491304
uniprot id: A0A6J3DC34
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZP domain family. ZPB subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Zona pellucida

219594:NETO1
gene id: 219594:NETO1
uniprot id: A0A6J3CMM5
uniprot id: A0A6J3CPQ3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:RIPPLY3
gene id: 219594:RIPPLY3
uniprot id: A0A6J3CJM5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ripply family.
messages: Nucleus

219594:LOC116495215
gene id: 219594:LOC116495215
uniprot id: A0A6J3DPP8
uniprot id: A0A6J3DU01
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCC family. Conjugate transporter (TC 3.A.1.208) subfamily.
messages: Cell membrane
messages: Membrane

219594:E2F6
gene id: 219594:E2F6
uniprot id: A0A6J3CT82
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the E2F/DP family.
messages: Nucleus

219594:LOXL2
gene id: 219594:LOXL2
uniprot id: A0A6J3E9V9
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lysyl oxidase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mediates the post-translational oxidative deamination of lysine residues on target proteins leading to the formation of deaminated lysine (allysine).
messages: The lysine tyrosylquinone cross-link (LTQ) is generated by condensation of the epsilon-amino group of a lysine with a topaquinone produced by oxidation of tyrosine.
messages: extracellular space

219594:CCKBR
gene id: 219594:CCKBR
uniprot id: A0A6J3EPY3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

219594:TCF25
gene id: 219594:TCF25
uniprot id: A0A6J3DJY4
uniprot id: A0A6J3DP69
names: Similarity
messages: Belongs to the TCF25 family.

219594:VAMP3
gene id: 219594:VAMP3
uniprot id: A0A6J3E7B7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptobrevin family.
messages: Membrane

219594:CRCP
gene id: 219594:CRCP
uniprot id: A0A6J3E504
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic RPC9 RNA polymerase subunit family.
messages: Nucleus

219594:LOC116489188
gene id: 219594:LOC116489188
uniprot id: A0A6J3CYE0
names: Similarity
messages: Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.

219594:TEKT5
gene id: 219594:TEKT5
uniprot id: A0A6J3DVP9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tektin family.
messages: flagellum

219594:PCNX1
gene id: 219594:PCNX1
uniprot id: A0A6J3D0X1
uniprot id: A0A6J3D399
uniprot id: A0A6J3D3J9
uniprot id: A0A6J3D5U6
uniprot id: A0A6J3D5V1
uniprot id: A0A6J3D6Q8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pecanex family.
messages: Membrane

219594:LOC116488610
gene id: 219594:LOC116488610
uniprot id: A0A6J3CY14
names: Similarity
messages: Belongs to the cornifelin family.

219594:PLK1
gene id: 219594:PLK1
uniprot id: A0A6J3DU85
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. CDC5/Polo subfamily.
messages: Midbody
messages: Nucleus
messages: centrosome

219594:DDX24
gene id: 219594:DDX24
uniprot id: A0A6J3D0M8
names: Domain
names: Function
names: Similarity
messages: Belongs to the DEAD box helicase family.
messages: RNA helicase.
messages: The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.

219594:KDSR
gene id: 219594:KDSR
uniprot id: A0A6J3CL96
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

219594:PREPL
gene id: 219594:PREPL
uniprot id: A0A6J3CMN9
names: Similarity
messages: Belongs to the peptidase S9A family.

219594:L3HYPDH
gene id: 219594:L3HYPDH
uniprot id: A0A6J3D2P8
names: Similarity
messages: Belongs to the proline racemase family.

219594:GNGT2
gene id: 219594:GNGT2
uniprot id: A0A6J3E541
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G protein gamma family.
messages: Cell membrane
messages: G proteins are composed of 3 units; alpha, beta and gamma.
messages: Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.

219594:CPNE2
gene id: 219594:CPNE2
uniprot id: A0A6J3DP77
names: Similarity
messages: Belongs to the copine family.

219594:MAPKAP1
gene id: 219594:MAPKAP1
uniprot id: A0A6J3E201
uniprot id: A0A6J3E353
names: Similarity
messages: Belongs to the SIN1 family.

219594:PPM1E
gene id: 219594:PPM1E
uniprot id: A0A6J3E0D9
names: Similarity
messages: Belongs to the PP2C family.

219594:CAP2
gene id: 219594:CAP2
uniprot id: A0A6J3CLC8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CAP family.
messages: Cell membrane

219594:PPIC
gene id: 219594:PPIC
uniprot id: A0A6J3EI91
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

219594:GCAT
gene id: 219594:GCAT
uniprot id: A0A6J3EQR4
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.

219594:PAIP2B
gene id: 219594:PAIP2B
uniprot id: A0A6J3CZE4
names: Similarity
messages: Belongs to the PAIP2 family.

219594:AOPEP
gene id: 219594:AOPEP
uniprot id: A0A6J3EL03
names: Similarity
messages: Belongs to the peptidase M1 family.

219594:EIF6
gene id: 219594:EIF6
uniprot id: A0A6J3DWX8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-6 family.
messages: Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. May also be involved in ribosome biogenesis.
messages: Cytoplasm
messages: Monomer. Associates with the 60S ribosomal subunit.
messages: nucleolus

219594:BSX
gene id: 219594:BSX
uniprot id: A0A6J3E3G5
names: Subcellular Location Annotation
messages: Nucleus

219594:BECN1
gene id: 219594:BECN1
uniprot id: A0A6J3E5V6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the beclin family.
messages: Endoplasmic reticulum membrane
messages: Endosome membrane
messages: Membrane
messages: Mitochondrion membrane
messages: autophagosome
messages: trans-Golgi network membrane

219594:GUK1
gene id: 219594:GUK1
uniprot id: A0A6J3CI71
uniprot id: A0A6J3CK34
names: Similarity
messages: Belongs to the guanylate kinase family.

219594:PDGFRA
gene id: 219594:PDGFRA
uniprot id: A0A6J3CUU6
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.
messages: Cell membrane
messages: Interacts with homodimeric PDGFA, PDGFB and PDGFC, and with heterodimers formed by PDGFA and PDGFB. Monomer in the absence of bound ligand.
messages: Membrane
messages: Present in an inactive conformation in the absence of bound ligand. Binding of PDGFA and/or PDGFB leads to dimerization and activation by autophosphorylation on tyrosine residues.
messages: Tyrosine-protein kinase that acts as a cell-surface receptor for PDGFA, PDGFB and PDGFC and plays an essential role in the regulation of embryonic development, cell proliferation, survival and chemotaxis. Depending on the context, promotes or inhibits cell proliferation and cell migration. Plays an important role in the differentiation of bone marrow-derived mesenchymal stem cells. Required for normal skeleton development.

219594:PLCB2
gene id: 219594:PLCB2
uniprot id: A0A6J3D267
names: Cofactor
names: Function
messages: Binds 1 Ca(2+) ion per subunit.
messages: The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes.

219594:LOC116485434
gene id: 219594:LOC116485434
uniprot id: A0A6J3CIL0
names: Similarity
names: Subunit
messages: Belongs to the avian keratin family.
messages: The avian keratins (F-ker, S-ker, C-ker and B-ker) are a complex mixture of very similar polypeptides.

219594:TSPAN12
gene id: 219594:TSPAN12
uniprot id: A0A6J3D2Q2
uniprot id: A0A6J3D8K0
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

219594:CHRFAM7A
gene id: 219594:CHRFAM7A
uniprot id: A0A6J3DJF2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

219594:LOC116491121
gene id: 219594:LOC116491121
uniprot id: A0A6J3DB65
names: Similarity
messages: Belongs to the AB hydrolase superfamily. Lipase family.

219594:LOC116489297
gene id: 219594:LOC116489297
uniprot id: A0A6J3CZ85
names: Similarity
messages: Belongs to the copper type II ascorbate-dependent monooxygenase family.

219594:ESF1
gene id: 219594:ESF1
uniprot id: A0A6J3CP97
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ESF1 family.
messages: nucleolus

219594:ADAMTS12
gene id: 219594:ADAMTS12
uniprot id: A0A6J3ECX0
names: Caution
names: Cofactor
names: Subcellular Location Annotation
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

219594:LOC116486628
gene id: 219594:LOC116486628
uniprot id: A0A6J3CKB0
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily.

219594:ETV5
gene id: 219594:ETV5
uniprot id: A0A6J3DDQ3
uniprot id: A0A6J3DJC7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

219594:DTNB
gene id: 219594:DTNB
uniprot id: A0A6J3CLZ5
uniprot id: A0A6J3CLZ7
uniprot id: A0A6J3CNQ7
uniprot id: A0A6J3CPM8
uniprot id: A0A6J3CRX6
uniprot id: A0A6J3CT00
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dystrophin family. Dystrobrevin subfamily.
messages: Cytoplasm

219594:REV3L
gene id: 219594:REV3L
uniprot id: A0A6J3CLR4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-B family.
messages: Nucleus

219594:WASL
gene id: 219594:WASL
uniprot id: A0A6J3D128
names: Subcellular Location Annotation
messages: Nucleus

219594:LOC116494012
gene id: 219594:LOC116494012
uniprot id: A0A6J3DJF1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the borealin family.
messages: centromere

219594:CENPU
gene id: 219594:CENPU
uniprot id: A0A6J3CXE2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CENP-U/AME1 family.
messages: Nucleus

219594:RAD23B
gene id: 219594:RAD23B
uniprot id: A0A6J3ED39
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RAD23 family.
messages: Cytoplasm
messages: Multiubiquitin chain receptor involved in modulation of proteasomal degradation. Involved in nucleotide excision repair.
messages: Nucleus

219594:SPTLC2
gene id: 219594:SPTLC2
uniprot id: A0A6J3CXE7
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.

219594:ACSL5
gene id: 219594:ACSL5
uniprot id: A0A6J3DD54
uniprot id: A0A6J3DDI1
names: Function
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.
messages: Catalyzes the conversion of long-chain fatty acids to their active form acyl-CoAs for both synthesis of cellular lipids, and degradation via beta-oxidation.

219594:SERP1
gene id: 219594:SERP1
uniprot id: A0A6J3DJB9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RAMP4 family.
messages: Endoplasmic reticulum membrane
messages: May interact with target proteins during translocation into the lumen of the endoplasmic reticulum. May protect unfolded target proteins against degradation and facilitate correct glycosylation.
messages: Membrane

219594:NFIA
gene id: 219594:NFIA
uniprot id: A0A6J3D8G4
uniprot id: A0A6J3D8G9
uniprot id: A0A6J3DB67
uniprot id: A0A6J3DB72
uniprot id: A0A6J3DB92
uniprot id: A0A6J3DC18
uniprot id: A0A6J3DC25
uniprot id: A0A6J3DC31
uniprot id: A0A6J3DE50
uniprot id: A0A6J3DE53
uniprot id: A0A6J3DE59
uniprot id: A0A6J3DEF0
uniprot id: A0A6J3DEF5
uniprot id: A0A6J3DEG6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CTF/NF-I family.
messages: Binds DNA as a homodimer.
messages: Nucleus
messages: Recognizes and binds the palindromic sequence 5'-TTGGCNNNNNGCCAA-3' present in viral and cellular promoters and in the origin of replication of adenovirus type 2. These proteins are individually capable of activating transcription and replication.

219594:FOXE1
gene id: 219594:FOXE1
uniprot id: A0A6J3EIF6
names: Subcellular Location Annotation
messages: Nucleus

219594:MAGOH
gene id: 219594:MAGOH
uniprot id: A0A6J3DFK6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mago nashi family.
messages: Nucleus

219594:LOC116487498
gene id: 219594:LOC116487498
uniprot id: A0A6J3CSW2
names: Subcellular Location Annotation
messages: Nucleus

219594:ATP5F1C
gene id: 219594:ATP5F1C
uniprot id: A0A6J3EGD3
uniprot id: A0A6J3EK56
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(1) domain and the central stalk which is part of the complex rotary element. The gamma subunit protrudes into the catalytic domain formed of alpha(3)beta(3). Rotation of the central stalk against the surrounding alpha(3)beta(3) subunits leads to hydrolysis of ATP in three separate catalytic sites on the beta subunits.

219594:FGD6
gene id: 219594:FGD6
uniprot id: A0A6J3ENV5
names: Subcellular Location Annotation
messages: cytoskeleton

219594:SEMA3B
gene id: 219594:SEMA3B
uniprot id: A0A6J3DI80
names: Caution
names: Similarity
messages: Belongs to the semaphorin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:AK3
gene id: 219594:AK3
uniprot id: A0A6J3ECZ3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family. AK3 subfamily.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon GTP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent GTP hydrolysis.
messages: Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Has GTP:AMP phosphotransferase and ITP:AMP phosphotransferase activities.
messages: Mitochondrion matrix
messages: Monomer.

219594:RPS15
gene id: 219594:RPS15
uniprot id: A0A6J3E6U6
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Component of the small ribosomal subunit.

219594:BMP4
gene id: 219594:BMP4
uniprot id: A0A6J3D097
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TGF-beta family.
messages: Secreted

219594:ADD1
gene id: 219594:ADD1
uniprot id: A0A6J3CTX3
uniprot id: A0A6J3CTX7
uniprot id: A0A6J3CTY2
uniprot id: A0A6J3CW68
uniprot id: A0A6J3CW72
uniprot id: A0A6J3CW76
uniprot id: A0A6J3CWK8
uniprot id: A0A6J3CWL1
uniprot id: A0A6J3CWL6
uniprot id: A0A6J3CYZ7
uniprot id: A0A6J3CZ01
uniprot id: A0A6J3D001
uniprot id: A0A6J3D033
names: Similarity
messages: Belongs to the aldolase class II family. Adducin subfamily.

219594:ZDHHC8
gene id: 219594:ZDHHC8
uniprot id: A0A6J3DY72
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

219594:STK39
gene id: 219594:STK39
uniprot id: A0A6J3D526
uniprot id: A0A6J3D7M8
names: Similarity
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.

219594:GPX3
gene id: 219594:GPX3
uniprot id: A0A6J3DPW9
names: Similarity
messages: Belongs to the glutathione peroxidase family.

219594:VOPP1
gene id: 219594:VOPP1
uniprot id: A0A6J3CHV1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VOPP1/ECOP family.
messages: Cytoplasmic vesicle membrane
messages: Endosome membrane
messages: Late endosome membrane
messages: Lysosome membrane
messages: Membrane

219594:POMT2
gene id: 219594:POMT2
uniprot id: A0A6J3D3V7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 39 family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Transfers mannose from Dol-P-mannose to Ser or Thr residues on proteins.

219594:LOC116496256
gene id: 219594:LOC116496256
uniprot id: A0A6J3DYU9
names: Similarity
messages: Belongs to the GST superfamily. Theta family.

219594:LIFR
gene id: 219594:LIFR
uniprot id: A0A6J3EL08
uniprot id: A0A6J3EL35
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type I cytokine receptor family. Type 2 subfamily.
messages: Membrane

219594:MFSD6
gene id: 219594:MFSD6
uniprot id: A0A6J3D584
uniprot id: A0A6J3D7T1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. MFSD6 family.
messages: Membrane

219594:LPCAT3
gene id: 219594:LPCAT3
uniprot id: A0A6J3ENN0
names: Subcellular Location Annotation
messages: Membrane

219594:LOC116485687
gene id: 219594:LOC116485687
uniprot id: A0A6J3CG75
names: Similarity
names: Subunit
messages: Belongs to the avian keratin family.
messages: The avian keratins (F-ker, S-ker, C-ker and B-ker) are a complex mixture of very similar polypeptides.

219594:PIK3C3
gene id: 219594:PIK3C3
uniprot id: A0A6J3ED77
uniprot id: A0A6J3EI20
names: Similarity
messages: Belongs to the PI3/PI4-kinase family. Type III PI4K subfamily.

219594:DGKB
gene id: 219594:DGKB
uniprot id: A0A6J3CHV3
uniprot id: A0A6J3CHV8
uniprot id: A0A6J3CJC3
uniprot id: A0A6J3CJC8
uniprot id: A0A6J3CKJ1
uniprot id: A0A6J3CMH7
uniprot id: A0A6J3CNZ2
uniprot id: A0A6J3CNZ6
names: Similarity
messages: Belongs to the eukaryotic diacylglycerol kinase family.

219594:MRPS27
gene id: 219594:MRPS27
uniprot id: A0A6J3EKZ8
names: Subcellular Location Annotation
messages: Mitochondrion

219594:GALNT1
gene id: 219594:GALNT1
uniprot id: A0A6J3CHL4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
messages: Golgi apparatus membrane
messages: Membrane

219594:CDS1
gene id: 219594:CDS1
uniprot id: A0A6J3CZH5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Catalyzes the conversion of phosphatidic acid (PA) to CDP-diacylglycerol (CDP-DAG), an essential intermediate in the synthesis of phosphatidylglycerol, cardiolipin and phosphatidylinositol.
messages: Membrane

219594:LOC116496138
gene id: 219594:LOC116496138
uniprot id: A0A6J3E070
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

219594:NDUFV3
gene id: 219594:NDUFV3
uniprot id: A0A6J3E4H3
uniprot id: A0A6J3E8V2
names: Function
names: Similarity
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. May be the terminally assembled subunit of Complex I.
messages: Belongs to the complex I NDUFV3 subunit family.
messages: Complex I is composed of 45 different subunits. This is a component of the flavoprotein-sulfur (FP) fragment of the enzyme.

219594:EIF4EBP2
gene id: 219594:EIF4EBP2
uniprot id: A0A6J3DCI5
names: Similarity
messages: Belongs to the eIF4E-binding protein family.

219594:LOC116494045
gene id: 219594:LOC116494045
uniprot id: A0A6J3DNS0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

219594:GLRA2
gene id: 219594:GLRA2
uniprot id: A0A6J3EJ30
uniprot id: A0A6J3EPG2
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synapse
messages: Synaptic cell membrane

219594:B3GNT2
gene id: 219594:B3GNT2
uniprot id: A0A6J3CPI2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane

219594:NADK2
gene id: 219594:NADK2
uniprot id: A0A6J3EE04
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NAD kinase family.
messages: Homodimer.
messages: Mitochondrial NAD(+) kinase that phosphorylates NAD(+) to yield NADP(+). Can use both ATP or inorganic polyphosphate as the phosphoryl donor.
messages: Mitochondrion

219594:UHRF2
gene id: 219594:UHRF2
uniprot id: A0A6J3EEA6
uniprot id: A0A6J3EJC1
uniprot id: A0A6J3EJG6
names: Domain
names: Function
names: Subcellular Location Annotation
messages: Multi domain E3 ubiquitin ligase that also plays a role in DNA methylation and histone modifications.
messages: Nucleus
messages: The YDG domain mediates the interaction with histone H3.
messages: The tudor-like regions specifically recognize and bind histone H3 unmethylated at 'Arg-2' (H3R2me0), while the PHD-type zinc finger specifically recognizes and binds histone H3 trimethylated at 'Lys-9' (H3K9me3).

219594:NOL10
gene id: 219594:NOL10
uniprot id: A0A6J3CVL1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat NOL10/ENP2 family.
messages: nucleolus

219594:LOC116487509
gene id: 219594:LOC116487509
uniprot id: A0A6J3CMX9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor T2R family.
messages: Membrane

219594:LOC116486847
gene id: 219594:LOC116486847
uniprot id: A0A6J3CMF4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 23 family.
messages: Secreted

219594:SEPTIN5
gene id: 219594:SEPTIN5
uniprot id: A0A6J3DTD7
uniprot id: A0A6J3DZF1
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.

219594:CKS2
gene id: 219594:CKS2
uniprot id: A0A6J3EJK6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CKS family.
messages: Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function.
messages: Forms a homohexamer that can probably bind six kinase subunits.

219594:ATG101
gene id: 219594:ATG101
uniprot id: A0A6J3EFP2
names: Similarity
messages: Belongs to the ATG101 family.

219594:RPL12
gene id: 219594:RPL12
uniprot id: A0A6J3E2L2
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Binds directly to 26S ribosomal RNA.

219594:DPH2
gene id: 219594:DPH2
uniprot id: A0A6J3DCT1
names: Function
names: Similarity
messages: Belongs to the DPH1/DPH2 family. DPH2 subfamily.
messages: Required for the first step of diphthamide biosynthesis, a post-translational modification of histidine which occurs in elongation factor 2. DPH1 and DPH2 transfer a 3-amino-3-carboxypropyl (ACP) group from S-adenosyl-L-methionine (SAM) to a histidine residue, the reaction is assisted by a reduction system comprising DPH3 and a NADH-dependent reductase. Facilitates the reduction of the catalytic iron-sulfur cluster found in the DPH1 subunit.

219594:LOC116500825
gene id: 219594:LOC116500825
uniprot id: A0A6J3EJA1
names: Similarity
messages: Belongs to the SERF family.

219594:TOR3A
gene id: 219594:TOR3A
uniprot id: A0A6J3DCH7
names: Similarity
messages: Belongs to the ClpA/ClpB family. Torsin subfamily.

219594:NIPSNAP1
gene id: 219594:NIPSNAP1
uniprot id: A0A6J3DUD4
names: Similarity
messages: Belongs to the NipSnap family.

219594:GRHL3
gene id: 219594:GRHL3
uniprot id: A0A6J3E529
names: Subcellular Location Annotation
messages: Nucleus

219594:PDCD5
gene id: 219594:PDCD5
uniprot id: A0A6J3DQ01
names: Similarity
messages: Belongs to the PDCD5 family.

219594:HAGH
gene id: 219594:HAGH
uniprot id: A0A6J3DPH8
uniprot id: A0A6J3DRS5
names: Similarity
messages: Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.

219594:GNS
gene id: 219594:GNS
uniprot id: A0A6J3EPJ4
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfatase family.
messages: Lysosome
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

219594:SNX2
gene id: 219594:SNX2
uniprot id: A0A6J3ED66
uniprot id: A0A6J3EI05
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sorting nexin family.
messages: Early endosome membrane
messages: Endosome membrane
messages: Membrane
messages: lamellipodium

219594:LOC116501267
gene id: 219594:LOC116501267
uniprot id: A0A6J3EHI6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Cell membrane
messages: Membrane

219594:FGFBP3
gene id: 219594:FGFBP3
uniprot id: A0A6J3DA05
names: Similarity
messages: Belongs to the fibroblast growth factor-binding protein family.

219594:LOC116500121
gene id: 219594:LOC116500121
uniprot id: A0A6J3EG77
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

219594:PPT1
gene id: 219594:PPT1
uniprot id: A0A6J3E9E5
names: Similarity
messages: Belongs to the palmitoyl-protein thioesterase family.

219594:FGF3
gene id: 219594:FGF3
uniprot id: A0A6J3D460
names: Similarity
messages: Belongs to the heparin-binding growth factors family.

219594:TMEM242
gene id: 219594:TMEM242
uniprot id: A0A6J3CUS6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM242 family.
messages: Membrane

219594:SLC25A51
gene id: 219594:SLC25A51
uniprot id: A0A6J3EET3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

219594:C19H9orf116
gene id: 219594:C19H9orf116
uniprot id: A0A6J3DYD9
names: Subcellular Location Annotation
messages: cilium axoneme

219594:SERPINE2
gene id: 219594:SERPINE2
uniprot id: A0A6J3DCM6
uniprot id: A0A6J3DGJ0
uniprot id: A0A6J3DI66
names: Similarity
messages: Belongs to the serpin family.

219594:EML5
gene id: 219594:EML5
uniprot id: A0A6J3D053
uniprot id: A0A6J3D2R4
uniprot id: A0A6J3D606
names: Function
names: Similarity
messages: Belongs to the WD repeat EMAP family.
messages: May modify the assembly dynamics of microtubules, such that microtubules are slightly longer, but more dynamic.

219594:B3GALT2
gene id: 219594:B3GALT2
uniprot id: A0A6J3DEI9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane

219594:CERS6
gene id: 219594:CERS6
uniprot id: A0A6J3D626
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Nucleus

219594:LOC116488954
gene id: 219594:LOC116488954
uniprot id: A0A6J3CX48
names: Similarity
messages: Belongs to the DOCK family.

219594:GNPDA2
gene id: 219594:GNPDA2
uniprot id: A0A6J3CRX7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family.
messages: Cytoplasm
messages: Homohexamer.

219594:LOC116501337
gene id: 219594:LOC116501337
uniprot id: A0A6J3EMX5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

219594:PAQR9
gene id: 219594:PAQR9
uniprot id: A0A6J3DE08
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ADIPOR family.
messages: Membrane

219594:GLUD1
gene id: 219594:GLUD1
uniprot id: A0A6J3DBR4
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

219594:LOC116500245
gene id: 219594:LOC116500245
uniprot id: A0A6J3EBK4
uniprot id: A0A6J3EBK9
uniprot id: A0A6J3ECV9
uniprot id: A0A6J3ECW6
uniprot id: A0A6J3EG96
uniprot id: A0A6J3EGA1
uniprot id: A0A6J3EGA5
uniprot id: A0A6J3EGK7
uniprot id: A0A6J3EGL2
uniprot id: A0A6J3EI56
uniprot id: A0A6J3EI62
names: Similarity
messages: Belongs to the MHC class I family.

219594:ATP13A3
gene id: 219594:ATP13A3
uniprot id: A0A6J3DFR6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily.
messages: Membrane

219594:TSNAX
gene id: 219594:TSNAX
uniprot id: A0A6J3CQA7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the translin family.
messages: Nucleus

219594:MAPK6
gene id: 219594:MAPK6
uniprot id: A0A6J3DJ09
names: Similarity
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MAP kinase subfamily.

219594:PDXK
gene id: 219594:PDXK
uniprot id: A0A6J3CHI3
uniprot id: A0A6J3CIK0
names: Similarity
messages: Belongs to the pyridoxine kinase family.

219594:SLC35E1
gene id: 219594:SLC35E1
uniprot id: A0A6J3EDG5
names: Subcellular Location Annotation
messages: Membrane

219594:TAS1R1
gene id: 219594:TAS1R1
uniprot id: A0A6J3E1V5
names: Subcellular Location Annotation
messages: Membrane

219594:LOC116487513
gene id: 219594:LOC116487513
uniprot id: A0A6J3CPU7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CENP-Q/OKP1 family.
messages: Nucleus

219594:LOC116495279
gene id: 219594:LOC116495279
uniprot id: A0A6J3DUE8
names: Similarity
messages: Belongs to the cytochrome P450 family.

219594:LOC116501433
gene id: 219594:LOC116501433
uniprot id: A0A6J3EI63
names: Similarity
messages: Belongs to the peptidase M14 family.

219594:TP53INP1
gene id: 219594:TP53INP1
uniprot id: A0A6J3CJ40
uniprot id: A0A6J3CMP0
names: Subcellular Location Annotation
messages: PML body
messages: autophagosome
messages: cytosol

219594:TMEM121
gene id: 219594:TMEM121
uniprot id: A0A6J3DFQ6
names: Similarity
messages: Belongs to the TMEM121 family.

219594:TAC1
gene id: 219594:TAC1
uniprot id: A0A6J3CNX8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tachykinin family.
messages: Secreted
messages: Tachykinins are active peptides which excite neurons, evoke behavioral responses, are potent vasodilators and secretagogues, and contract (directly or indirectly) many smooth muscles.

219594:NRXN3
gene id: 219594:NRXN3
uniprot id: A0A6J3CZK9
uniprot id: A0A6J3CZL4
uniprot id: A0A6J3CZL9
uniprot id: A0A6J3CZM6
uniprot id: A0A6J3D213
uniprot id: A0A6J3D218
uniprot id: A0A6J3D222
uniprot id: A0A6J3D259
uniprot id: A0A6J3D265
uniprot id: A0A6J3D270
uniprot id: A0A6J3D4J8
uniprot id: A0A6J3D4K7
uniprot id: A0A6J3D5I9
uniprot id: A0A6J3D5J1
uniprot id: A0A6J3D5J6
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the neurexin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

219594:SLC15A2
gene id: 219594:SLC15A2
uniprot id: A0A6J3D2C4
uniprot id: A0A6J3D880
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Apical cell membrane
messages: Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.
messages: Interacts (via extracellular domain region) with trypsin.
messages: Membrane

219594:ARMC10
gene id: 219594:ARMC10
uniprot id: A0A6J3E270
names: Similarity
messages: Belongs to the eutherian X-chromosome-specific Armcx family.

219594:HMCN1
gene id: 219594:HMCN1
uniprot id: A0A6J3DBZ0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:ITM2C
gene id: 219594:ITM2C
uniprot id: A0A6J3DEL9
uniprot id: A0A6J3DI23
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ITM2 family.
messages: Membrane

219594:TMOD2
gene id: 219594:TMOD2
uniprot id: A0A6J3DIY6
names: Subcellular Location Annotation
messages: cytoskeleton

219594:FLVCR1
gene id: 219594:FLVCR1
uniprot id: A0A6J3CTS2
names: Subcellular Location Annotation
messages: Membrane

219594:HMGN5
gene id: 219594:HMGN5
uniprot id: A0A6J3DP22
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HMGN family.
messages: Nucleus

219594:SOX4
gene id: 219594:SOX4
uniprot id: A0A6J3CNQ9
names: Subcellular Location Annotation
messages: Nucleus

219594:PKD2L2
gene id: 219594:PKD2L2
uniprot id: A0A6J3DNK1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polycystin family.
messages: Membrane

219594:BPI
gene id: 219594:BPI
uniprot id: A0A6J3DYD8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BPI/LBP/Plunc superfamily. BPI/LBP family.
messages: Monomer. Homodimer; disulfide-linked.
messages: Secreted
messages: The N- and C-terminal barrels adopt an identical fold despite having only 13% of conserved residues.
messages: The N-terminal region may be exposed to the interior of the granule, whereas the C-terminal portion may be embedded in the membrane. During phagocytosis and degranulation, proteases may be released and activated and cleave BPI at the junction of the N- and C-terminal portions of the molecule, providing controlled release of the N-terminal antibacterial fragment when bacteria are ingested.
messages: The cytotoxic action of BPI is limited to many species of Gram-negative bacteria; this specificity may be explained by a strong affinity of the very basic N-terminal half for the negatively charged lipopolysaccharides that are unique to the Gram-negative bacterial outer envelope.