216946:STURON RS03215
gene id: 216946:STURON_RS03215
uniprot id: A0A0K1P6M3
names: Subcellular Location Annotation
messages: Membrane

216946:STURON RS04480
gene id: 216946:STURON_RS04480
uniprot id: A0A0K1P747
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

216946:STURON RS01930
gene id: 216946:STURON_RS01930
uniprot id: A0A0K1P5S2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

216946:STURON RS00480
gene id: 216946:STURON_RS00480
uniprot id: A0A0K1P596
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

216946:STURON RS00255
gene id: 216946:STURON_RS00255
uniprot id: A0A0K1P553
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase delta chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

216946:STURON RS04515
gene id: 216946:STURON_RS04515
uniprot id: A0A0K1P893
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

216946:STURON RS02680
gene id: 216946:STURON_RS02680
uniprot id: A0A0K1P622
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvB family.
messages: Cytoplasm
messages: Has 3 domains, the large (RuvB-L) and small ATPase (RuvB-S) domains and the C-terminal head (RuvB-H) domain. The head domain binds DNA, while the ATPase domains jointly bind ATP, ADP or are empty depending on the state of the subunit in the translocation cycle. During a single DNA translocation step the structure of each domain remains the same, but their relative positions change.
messages: Homohexamer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time. Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange. Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration. The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration. Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.

216946:STURON RS04135
gene id: 216946:STURON_RS04135
uniprot id: A0A0K1P6W8
names: Function
names: Similarity
messages: Belongs to the HrcA family.
messages: Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons.

216946:STURON RS05055
gene id: 216946:STURON_RS05055
uniprot id: A0A0K1P7H0
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

216946:STURON RS01075
gene id: 216946:STURON_RS01075
uniprot id: A0A0K1P579
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.

216946:STURON RS00400
gene id: 216946:STURON_RS00400
uniprot id: A0A0K1P582
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

216946:STURON RS01785
gene id: 216946:STURON_RS01785
uniprot id: A0A0K1P5I5
names: Subcellular Location Annotation
messages: Membrane

216946:STURON RS03640
gene id: 216946:STURON_RS03640
uniprot id: A0A0K1P6J7
names: Subcellular Location Annotation
messages: Membrane

216946:STURON RS00935
gene id: 216946:STURON_RS00935
uniprot id: A0A0K1P518
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FPG family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

216946:STURON RS00490
gene id: 216946:STURON_RS00490
uniprot id: A0A0K1P4W3
names: Similarity
names: Subunit
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.
messages: Tetramer of two alpha and two beta subunits.

216946:STURON RS00220
gene id: 216946:STURON_RS00220
uniprot id: A0A0K1P5U1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

216946:STURON RS01495
gene id: 216946:STURON_RS01495
uniprot id: A0A0K1P5F7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

216946:STURON RS04450
gene id: 216946:STURON_RS04450
uniprot id: A0A0K1P7E9
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

216946:STURON RS02930
gene id: 216946:STURON_RS02930
uniprot id: A0A0K1P673
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

216946:STURON RS04740
gene id: 216946:STURON_RS04740
uniprot id: A0A0K1P8D7
names: Subcellular Location Annotation
messages: Membrane

216946:STURON RS04125
gene id: 216946:STURON_RS04125
uniprot id: A0A0K1P6V6
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

216946:STURON RS02065
gene id: 216946:STURON_RS02065
uniprot id: A0A0K1P6W9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uridine kinase family.
messages: Cytoplasm

216946:STURON RS02775
gene id: 216946:STURON_RS02775
uniprot id: A0A0K1P676
names: Subcellular Location Annotation
messages: cytosol

216946:STURON RS00420
gene id: 216946:STURON_RS00420
uniprot id: A0A0K1P4W1
names: Function
names: Similarity
messages: Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.
messages: Belongs to the organic radical-activating enzymes family.

216946:STURON RS05175
gene id: 216946:STURON_RS05175
uniprot id: A0A0K1P7I0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

216946:STURON RS01155
gene id: 216946:STURON_RS01155
uniprot id: A0A0K1P593
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Membrane

216946:STURON RS05395
gene id: 216946:STURON_RS05395
uniprot id: A0A0K1P7K4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidine kinase family.
messages: Cytoplasm
messages: Homotetramer.

216946:STURON RS00950
gene id: 216946:STURON_RS00950
uniprot id: A0A0K1P5G0
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

216946:STURON RS05090
gene id: 216946:STURON_RS05090
uniprot id: A0A0K1P8K1
names: Caution
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

216946:STURON RS00930
gene id: 216946:STURON_RS00930
uniprot id: A0A0K1P547
names: Function
names: Similarity
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.

216946:STURON RS00205
gene id: 216946:STURON_RS00205
uniprot id: A0A0K1P545
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

216946:STURON RS05305
gene id: 216946:STURON_RS05305
uniprot id: A0A0K1P7K3
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

216946:STURON RS03710
gene id: 216946:STURON_RS03710
uniprot id: A0A0K1P6P8
names: Subcellular Location Annotation
messages: Membrane

216946:STURON RS05165
gene id: 216946:STURON_RS05165
uniprot id: A0A1W6AYI9
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

216946:STURON RS03990
gene id: 216946:STURON_RS03990
uniprot id: A0A0K1P6T2
names: Caution
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

216946:STURON RS05180
gene id: 216946:STURON_RS05180
uniprot id: A0A0K1P7S6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis. Some bacteria have evolved a zinc-coordinating structure that stabilizes the LID domain.
messages: Cytoplasm
messages: Monomer.

216946:STURON RS05420
gene id: 216946:STURON_RS05420
uniprot id: A0A0K1P7K8
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

216946:STURON RS00375
gene id: 216946:STURON_RS00375
uniprot id: A0A0K1P4V5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.
messages: Belongs to the RNR ribonuclease family. RNase R subfamily.
messages: Cytoplasm

216946:STURON RS00670
gene id: 216946:STURON_RS00670
uniprot id: A0A0K1P4Y6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

216946:STURON RS00125
gene id: 216946:STURON_RS00125
uniprot id: A0A0K1P530
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein bS6.

216946:STURON RS02140
gene id: 216946:STURON_RS02140
uniprot id: A0A0K1P6Y3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
messages: Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
messages: Cytoplasm

216946:STURON RS05735
gene id: 216946:STURON_RS05735
uniprot id: A0A0K1P549
names: Subcellular Location Annotation
messages: Membrane

216946:STURON RS01490
gene id: 216946:STURON_RS01490
uniprot id: A0A0K1P6M7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-C family. PolC subfamily.
messages: Cytoplasm
messages: Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

216946:STURON RS05255
gene id: 216946:STURON_RS05255
uniprot id: A0A0K1P7T8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

216946:STURON RS04575
gene id: 216946:STURON_RS04575
uniprot id: A0A0K1P7G9
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

216946:STURON RS00095
gene id: 216946:STURON_RS00095
uniprot id: A0A0K1P4Q9
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

216946:STURON RS03605
gene id: 216946:STURON_RS03605
uniprot id: A0A0K1P6U1
names: Similarity
messages: Belongs to the glycosyl hydrolase 38 family.

216946:STURON RS02445
gene id: 216946:STURON_RS02445
uniprot id: A0A0K1P691
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta chain.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).

216946:STURON RS03550
gene id: 216946:STURON_RS03550
uniprot id: A0A0K1P7R6
names: Subcellular Location Annotation
messages: cytosol

216946:STURON RS01040
gene id: 216946:STURON_RS01040
uniprot id: A0A0K1P538
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

216946:STURON RS05560
gene id: 216946:STURON_RS05560
uniprot id: A0A0K1P7Z2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

216946:STURON RS03900
gene id: 216946:STURON_RS03900
uniprot id: A0A0K1P6S7
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

216946:STURON RS04075
gene id: 216946:STURON_RS04075
uniprot id: A0A0K1P6U6
names: Subcellular Location Annotation
messages: Membrane

216946:STURON RS02360
gene id: 216946:STURON_RS02360
uniprot id: A0A0K1P722
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

216946:STURON RS00500
gene id: 216946:STURON_RS00500
uniprot id: A0A0K1P4X2
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

216946:STURON RS04310
gene id: 216946:STURON_RS04310
uniprot id: A0A0K1P719
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase Y family.
messages: Cell membrane
messages: Endoribonuclease that initiates mRNA decay.

216946:STURON RS00535
gene id: 216946:STURON_RS00535
uniprot id: A0A0K1P4X4
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

216946:STURON RS01780
gene id: 216946:STURON_RS01780
uniprot id: A0A0K1P5P2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

216946:STURON RS03345
gene id: 216946:STURON_RS03345
uniprot id: A0A0K1P6H7
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

216946:STURON RS01055
gene id: 216946:STURON_RS01055
uniprot id: A0A0K1P5H9
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

216946:STURON RS05080
gene id: 216946:STURON_RS05080
uniprot id: A0A0K1P7H5
names: Similarity
messages: Belongs to the GARS family.

216946:STURON RS00090
gene id: 216946:STURON_RS00090
uniprot id: A0A0K1P5R6
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

216946:STURON RS02510
gene id: 216946:STURON_RS02510
uniprot id: A0A0K1P746
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

216946:STURON RS01230
gene id: 216946:STURON_RS01230
uniprot id: A0A0K1P5A4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

216946:STURON RS05130
gene id: 216946:STURON_RS05130
uniprot id: A0A0K1P7I2
names: Subcellular Location Annotation
messages: Membrane

216946:STURON RS05515
gene id: 216946:STURON_RS05515
uniprot id: A0A0K1P7Q2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

216946:STURON RS05155
gene id: 216946:STURON_RS05155
uniprot id: A0A0K1P7I7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

216946:STURON RS00995
gene id: 216946:STURON_RS00995
uniprot id: A0A0K1P564
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

216946:STURON RS02565
gene id: 216946:STURON_RS02565
uniprot id: A0A0K1P5Y8
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Homodimer.

216946:STURON RS02905
gene id: 216946:STURON_RS02905
uniprot id: A0A0K1P669
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

216946:STURON RS00765
gene id: 216946:STURON_RS00765
uniprot id: A0A0K1P5C1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LDH/MDH superfamily. LDH family.
messages: Catalyzes the conversion of lactate to pyruvate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

216946:STURON RS04755
gene id: 216946:STURON_RS04755
uniprot id: A0A0K1P7A0
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by ADP and other diphosphonucleosides, and allosterically inhibited by phosphoenolpyruvate.
messages: Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Prokaryotic clade 'B1' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

216946:STURON RS05150
gene id: 216946:STURON_RS05150
uniprot id: A0A0K1P7S1
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

216946:STURON RS05555
gene id: 216946:STURON_RS05555
uniprot id: A0A0K1P7P8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

216946:STURON RS05570
gene id: 216946:STURON_RS05570
uniprot id: A0A0K1P7N5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

216946:STURON RS02365
gene id: 216946:STURON_RS02365
uniprot id: A0A0K1P5U9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

216946:STURON RS05350
gene id: 216946:STURON_RS05350
uniprot id: A0A0K1P8Q8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

216946:STURON RS00875
gene id: 216946:STURON_RS00875
uniprot id: A0A0K1P5E2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

216946:STURON RS01635
gene id: 216946:STURON_RS01635
uniprot id: A0A0K1P5G3
names: Subcellular Location Annotation
messages: Membrane

216946:STURON RS04860
gene id: 216946:STURON_RS04860
uniprot id: A0A0K1P8F9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Membrane

216946:STURON RS05210
gene id: 216946:STURON_RS05210
uniprot id: A0A0K1P7J7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

216946:STURON RS00665
gene id: 216946:STURON_RS00665
uniprot id: A0A0K1P4Y8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

216946:STURON RS00955
gene id: 216946:STURON_RS00955
uniprot id: A0A0K1P552
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Monomer.

216946:STURON RS01560
gene id: 216946:STURON_RS01560
uniprot id: A0A0K1P5F1
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

216946:STURON RS00335
gene id: 216946:STURON_RS00335
uniprot id: A0A0K1P4S3
names: Similarity
messages: Belongs to the HPrK/P family.

216946:STURON RS03980
gene id: 216946:STURON_RS03980
uniprot id: A0A0K1P741
names: Function
names: Similarity
names: Subunit
messages: Belongs to the OMP decarboxylase family. Type 1 subfamily.
messages: Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
messages: Homodimer.

216946:STURON RS05390
gene id: 216946:STURON_RS05390
uniprot id: A0A0K1P7M6
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

216946:STURON RS01325
gene id: 216946:STURON_RS01325
uniprot id: A0A0K1P5C7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

216946:STURON RS00265
gene id: 216946:STURON_RS00265
uniprot id: A0A0K1P4S6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

216946:STURON RS04710
gene id: 216946:STURON_RS04710
uniprot id: A0A0K1P758
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

216946:STURON RS05475
gene id: 216946:STURON_RS05475
uniprot id: A0A0K1P8T3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the N7 position of a guanine in 16S rRNA.

216946:STURON RS04745
gene id: 216946:STURON_RS04745
uniprot id: A0A0K1P7A5
names: Similarity
messages: Belongs to the pyruvate kinase family.

216946:STURON RS00215
gene id: 216946:STURON_RS00215
uniprot id: A0A0K1P4R9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

216946:STURON RS00115
gene id: 216946:STURON_RS00115
uniprot id: A0A0K1P5S1
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with bS18 to 16S ribosomal RNA.

216946:STURON RS00380
gene id: 216946:STURON_RS00380
uniprot id: A0A0K1P578
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

216946:STURON RS05200
gene id: 216946:STURON_RS05200
uniprot id: A0A0K1P7I5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

216946:STURON RS00025
gene id: 216946:STURON_RS00025
uniprot id: A0A0K1P4M4
names: Similarity
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.

216946:STURON RS00160
gene id: 216946:STURON_RS00160
uniprot id: A0A0K1P4R2
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

216946:STURON RS00015
gene id: 216946:STURON_RS00015
uniprot id: A0A0K1P4N9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA which binds and tethers DNA polymerases and other proteins to the DNA. The DNA replisome complex has a single clamp-loading complex (3 tau and 1 each of delta, delta', psi and chi subunits) which binds 3 Pol III cores (1 core on the leading strand and 2 on the lagging strand) each with a beta sliding clamp dimer. Additional proteins in the replisome are other copies of gamma, psi and chi, Ssb, DNA helicase and RNA primase.

216946:STURON RS05485
gene id: 216946:STURON_RS05485
uniprot id: A0A0K1P7X8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

216946:STURON RS00045
gene id: 216946:STURON_RS00045
uniprot id: A0A0K1P4P4
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

216946:STURON RS03270
gene id: 216946:STURON_RS03270
uniprot id: A0A0K1P6G0
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated Cas9 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9/crRNA/tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer; Cas9 is inactive in the absence of the 2 guide RNAs (gRNA). Cas9 recognizes the protospacer adjacent motif (PAM) in the CRISPR repeat sequences to help distinguish self versus nonself, as targets within the bacterial CRISPR locus do not have PAMs. PAM recognition is also required for catalytic activity.
messages: Has 2 endonuclease domains. The discontinuous RuvC-like domain cleaves the target DNA noncomplementary to crRNA while the HNH nuclease domain cleaves the target DNA complementary to crRNA.
messages: Monomer. Binds crRNA and tracrRNA.

216946:STURON RS01410
gene id: 216946:STURON_RS01410
uniprot id: A0A0K1P6L7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

216946:STURON RS01250
gene id: 216946:STURON_RS01250
uniprot id: A0A0K1P6H3
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

216946:STURON RS02480
gene id: 216946:STURON_RS02480
uniprot id: A0A0K1P5Y1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

216946:STURON RS01190
gene id: 216946:STURON_RS01190
uniprot id: A0A0K1P595
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

216946:STURON RS05275
gene id: 216946:STURON_RS05275
uniprot id: A0A0K1P7J9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

216946:STURON RS05220
gene id: 216946:STURON_RS05220
uniprot id: A0A0K1P8N0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

216946:STURON RS02695
gene id: 216946:STURON_RS02695
uniprot id: A0A0K1P6C9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

216946:STURON RS00885
gene id: 216946:STURON_RS00885
uniprot id: A0A0K1P510
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

216946:STURON RS05235
gene id: 216946:STURON_RS05235
uniprot id: A0A0K1P7K2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

216946:STURON RS01320
gene id: 216946:STURON_RS01320
uniprot id: A0A0K1P5P1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

216946:STURON RS05445
gene id: 216946:STURON_RS05445
uniprot id: A0A0K1P7L2
names: Similarity
messages: Belongs to the RNase H family.

216946:STURON RS05850
gene id: 216946:STURON_RS05850
uniprot id: A0A0K1P516
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Membrane

216946:STURON RS03660
gene id: 216946:STURON_RS03660
uniprot id: A0A0K1P6P0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

216946:STURON RS04705
gene id: 216946:STURON_RS04705
uniprot id: A0A0K1P790
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

216946:STURON RS05005
gene id: 216946:STURON_RS05005
uniprot id: A0A0K1P7D8
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily.
messages: Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

216946:STURON RS03385
gene id: 216946:STURON_RS03385
uniprot id: A0A0K1P6G6
names: Subcellular Location Annotation
messages: Membrane

216946:STURON RS04440
gene id: 216946:STURON_RS04440
uniprot id: A0A0K1P879
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecU family.
messages: Cytoplasm

216946:STURON RS04285
gene id: 216946:STURON_RS04285
uniprot id: A0A0K1P714
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily.
messages: Cytoplasm
messages: Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity.

216946:STURON RS01990
gene id: 216946:STURON_RS01990
uniprot id: A0A0K1P6V4
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

216946:STURON RS03120
gene id: 216946:STURON_RS03120
uniprot id: A0A0K1P6K4
names: Subcellular Location Annotation
messages: Membrane

216946:STURON RS02570
gene id: 216946:STURON_RS02570
uniprot id: A0A0K1P6B5
names: Similarity
messages: Belongs to the XseB family.

216946:STURON RS01305
gene id: 216946:STURON_RS01305
uniprot id: A0A0K1P5B5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

216946:STURON RS00495
gene id: 216946:STURON_RS00495
uniprot id: A0A0K1P5Z5
names: Function
names: Similarity
messages: Belongs to the NrdI family.
messages: Probably involved in ribonucleotide reductase function.

216946:STURON RS01415
gene id: 216946:STURON_RS01415
uniprot id: A0A0K1P5E7
names: Function
names: Similarity
messages: Belongs to the dihydrofolate reductase family.
messages: Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.

216946:STURON RS03800
gene id: 216946:STURON_RS03800
uniprot id: A0A0K1P6P3
names: Similarity
messages: Belongs to the glycosyl hydrolase 18 family.

216946:STURON RS00040
gene id: 216946:STURON_RS00040
uniprot id: A0A0K1P5Q5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

216946:STURON RS05125
gene id: 216946:STURON_RS05125
uniprot id: A0A0K1P7R7
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

216946:STURON RS05535
gene id: 216946:STURON_RS05535
uniprot id: A0A0K1P7Y7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

216946:STURON RS04505
gene id: 216946:STURON_RS04505
uniprot id: A0A0K1P752
names: Similarity
messages: Belongs to the FBPase class 2 family.

216946:STURON RS02295
gene id: 216946:STURON_RS02295
uniprot id: A0A0K1P668
names: Subcellular Location Annotation
messages: Membrane

216946:STURON RS05505
gene id: 216946:STURON_RS05505
uniprot id: A0A0K1P7N8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

216946:STURON RS04175
gene id: 216946:STURON_RS04175
uniprot id: A0A0K1P6W6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

216946:STURON RS00195
gene id: 216946:STURON_RS00195
uniprot id: A0A0K1P5T5
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

216946:STURON RS00250
gene id: 216946:STURON_RS00250
uniprot id: A0A0K1P4T4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

216946:STURON RS00210
gene id: 216946:STURON_RS00210
uniprot id: A0A0K1P4Q4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

216946:STURON RS00770
gene id: 216946:STURON_RS00770
uniprot id: A0A0K1P4Z6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

216946:STURON RS03350
gene id: 216946:STURON_RS03350
uniprot id: A0A0K1P6E2
names: Subcellular Location Annotation
messages: Membrane

216946:STURON RS05550
gene id: 216946:STURON_RS05550
uniprot id: A0A0K1P8U9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm

216946:STURON RS05455
gene id: 216946:STURON_RS05455
uniprot id: A0A0K1P7M8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

216946:STURON RS03940
gene id: 216946:STURON_RS03940
uniprot id: A0A0K1P6S4
names: Similarity
messages: Belongs to the pyrroline-5-carboxylate reductase family.

216946:STURON RS04110
gene id: 216946:STURON_RS04110
uniprot id: A0A0K1P6W3
names: Subcellular Location Annotation
messages: Membrane

216946:STURON RS03575
gene id: 216946:STURON_RS03575
uniprot id: A0A0K1P6K0
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

216946:STURON RS04925
gene id: 216946:STURON_RS04925
uniprot id: A0A0K1P7C2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 3 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).
messages: Consists of three domains: the N-terminal catalytic domain, the anticodon-binding domain and the C-terminal extension.
messages: Cytoplasm
messages: Homodimer.

216946:STURON RS02875
gene id: 216946:STURON_RS02875
uniprot id: A0A0K1P693
names: Activity Regulation
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Inhibited by fructose 1,6-bisphosphate (FBP).
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.

216946:STURON RS05085
gene id: 216946:STURON_RS05085
uniprot id: A0A0K1P7E7
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

216946:STURON RS01480
gene id: 216946:STURON_RS01480
uniprot id: A0A0K1P5F0
names: Caution
names: Function
names: Similarity
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

216946:STURON RS05020
gene id: 216946:STURON_RS05020
uniprot id: A0A0K1P7F2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

216946:STURON RS00425
gene id: 216946:STURON_RS00425
uniprot id: A0A0K1P587
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

216946:STURON RS01060
gene id: 216946:STURON_RS01060
uniprot id: A0A0K1P572
names: Subcellular Location Annotation
messages: Membrane

216946:STURON RS04055
gene id: 216946:STURON_RS04055
uniprot id: A0A0K1P827
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

216946:STURON RS01545
gene id: 216946:STURON_RS01545
uniprot id: A0A0K1P5G6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer.

216946:STURON RS01865
gene id: 216946:STURON_RS01865
uniprot id: A0A0K1P5L1
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

216946:STURON RS01555
gene id: 216946:STURON_RS01555
uniprot id: A0A0K1P5I6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of glycine to tRNA(Gly).
messages: Cytoplasm
messages: Homodimer.

216946:STURON RS01895
gene id: 216946:STURON_RS01895
uniprot id: A0A0K1P5L4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
messages: Could methylate the ribose at the nucleotide 34 wobble position in tRNA.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

216946:STURON RS00135
gene id: 216946:STURON_RS00135
uniprot id: A0A0K1P4Q8
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity.

216946:STURON RS02125
gene id: 216946:STURON_RS02125
uniprot id: A0A0K1P635
names: Cofactor
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. NagA family.
messages: Binds 1 divalent metal cation per subunit.

216946:STURON RS00980
gene id: 216946:STURON_RS00980
uniprot id: A0A0K1P557
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily.
messages: Cytoplasm
messages: Homodimer, may be a subunit of the RNA degradosome.

216946:STURON RS01825
gene id: 216946:STURON_RS01825
uniprot id: A0A0K1P5Q2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

216946:STURON RS01645
gene id: 216946:STURON_RS01645
uniprot id: A0A0K1P5I0
names: Cofactor
messages: Binds 1 Mg(2+) ion per trimer.

216946:STURON RS04660
gene id: 216946:STURON_RS04660
uniprot id: A0A0K1P748
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

216946:STURON RS05460
gene id: 216946:STURON_RS05460
uniprot id: A0A0K1P7X5
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

216946:STURON RS01855
gene id: 216946:STURON_RS01855
uniprot id: A0A0K1P5J8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

216946:STURON RS04190
gene id: 216946:STURON_RS04190
uniprot id: A0A0K1P783
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

216946:STURON RS03825
gene id: 216946:STURON_RS03825
uniprot id: A0A0K1P6R7
names: Similarity
messages: Belongs to the lipase/esterase LIP3/BchO family.

216946:STURON RS02400
gene id: 216946:STURON_RS02400
uniprot id: A0A0K1P604
names: Subcellular Location Annotation
messages: Membrane

216946:STURON RS00410
gene id: 216946:STURON_RS00410
uniprot id: A0A0K1P4V4
names: Similarity
messages: Belongs to the PNP/UDP phosphorylase family.

216946:STURON RS01070
gene id: 216946:STURON_RS01070
uniprot id: A0A0K1P6D6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

216946:STURON RS00900
gene id: 216946:STURON_RS00900
uniprot id: A0A0K1P5E8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThiI family.
messages: Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.
messages: Cytoplasm

216946:STURON RS02650
gene id: 216946:STURON_RS02650
uniprot id: A0A0K1P652
names: Subcellular Location Annotation
messages: Membrane

216946:STURON RS01700
gene id: 216946:STURON_RS01700
uniprot id: A0A0K1P5V4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

216946:STURON RS01845
gene id: 216946:STURON_RS01845
uniprot id: A0A0K1P5Y0
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

216946:STURON RS02555
gene id: 216946:STURON_RS02555
uniprot id: A0A0K1P5Z6
names: Similarity
messages: Belongs to the TlyA family.

216946:STURON RS00640
gene id: 216946:STURON_RS00640
uniprot id: A0A0K1P4Y4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

216946:STURON RS01985
gene id: 216946:STURON_RS01985
uniprot id: A0A0K1P5L2
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.

216946:STURON RS00340
gene id: 216946:STURON_RS00340
uniprot id: A0A0K1P4U3
names: Similarity
messages: Belongs to the Lgt family.

216946:STURON RS01605
gene id: 216946:STURON_RS01605
uniprot id: A0A0K1P5J5
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

216946:STURON RS02885
gene id: 216946:STURON_RS02885
uniprot id: A0A0K1P7B3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

216946:STURON RS03975
gene id: 216946:STURON_RS03975
uniprot id: A0A0K1P6U0
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

216946:STURON RS05170
gene id: 216946:STURON_RS05170
uniprot id: A0A0K1P8L9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

216946:STURON RS02770
gene id: 216946:STURON_RS02770
uniprot id: A0A0K1P6E1
names: Subcellular Location Annotation
messages: Membrane

216946:STURON RS04560
gene id: 216946:STURON_RS04560
uniprot id: A0A0K1P731
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Inhibited by UTP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

216946:STURON RS03520
gene id: 216946:STURON_RS03520
uniprot id: A0A0K1P6H6
names: Subcellular Location Annotation
messages: Membrane

216946:STURON RS04775
gene id: 216946:STURON_RS04775
uniprot id: A0A0K1P7K5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm

216946:STURON RS03610
gene id: 216946:STURON_RS03610
uniprot id: A0A0K1P6N2
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

216946:STURON RS05415
gene id: 216946:STURON_RS05415
uniprot id: A0A0K1P7N2
names: Cofactor
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.

216946:STURON RS05245
gene id: 216946:STURON_RS05245
uniprot id: A0A0K1P8N6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

216946:STURON RS01735
gene id: 216946:STURON_RS01735
uniprot id: A0A0K1P5H7
names: Subcellular Location Annotation
messages: Membrane

216946:STURON RS02095
gene id: 216946:STURON_RS02095
uniprot id: A0A0K1P5P9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 2 subfamily.
messages: Cell membrane
messages: Heterotetramer composed of ParC and ParE.
messages: Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.

216946:STURON RS04300
gene id: 216946:STURON_RS04300
uniprot id: A0A0K1P6Z7
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

216946:STURON RS01515
gene id: 216946:STURON_RS01515
uniprot id: A0A0K1P6N1
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial diacylglycerol kinase family.
messages: Membrane
messages: Mn(2+), Zn(2+), Cd(2+) and Co(2+) support activity to lesser extents.

216946:STURON RS00300
gene id: 216946:STURON_RS00300
uniprot id: A0A0K1P4U4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm

216946:STURON RS05290
gene id: 216946:STURON_RS05290
uniprot id: A0A0K1P7I4
names: Subcellular Location Annotation
messages: Membrane

216946:STURON RS01775
gene id: 216946:STURON_RS01775
uniprot id: A0A0K1P5W7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

216946:STURON RS01740
gene id: 216946:STURON_RS01740
uniprot id: A0A0K1P6R0
names: Subcellular Location Annotation
messages: Membrane

216946:STURON RS05355
gene id: 216946:STURON_RS05355
uniprot id: A0A0K1P7L1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

216946:STURON RS00295
gene id: 216946:STURON_RS00295
uniprot id: A0A0K1P5V5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arginine deiminase family.
messages: Cytoplasm

216946:STURON RS04555
gene id: 216946:STURON_RS04555
uniprot id: A0A0K1P762
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

216946:STURON RS00440
gene id: 216946:STURON_RS00440
uniprot id: A0A0K1P5Y4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

216946:STURON RS05215
gene id: 216946:STURON_RS05215
uniprot id: A0A0K1P7G6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

216946:STURON RS00230
gene id: 216946:STURON_RS00230
uniprot id: A0A0K1P548
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
messages: Allosterically activated by GTP.
messages: Belongs to the UPRTase family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.
messages: Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.

216946:STURON RS03995
gene id: 216946:STURON_RS03995
uniprot id: A0A0K1P817
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.

216946:STURON RS00185
gene id: 216946:STURON_RS00185
uniprot id: A0A0K1P4Q1
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

216946:STURON RS00150
gene id: 216946:STURON_RS00150
uniprot id: A0A0K1P535
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
messages: Cytoplasm
messages: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.

216946:STURON RS04655
gene id: 216946:STURON_RS04655
uniprot id: A0A0K1P780
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

216946:STURON RS05545
gene id: 216946:STURON_RS05545
uniprot id: A0A0K1P7N1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

216946:STURON RS05590
gene id: 216946:STURON_RS05590
uniprot id: A0A0K1P7R5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
messages: Binds 1 potassium ion per subunit.
messages: Cytoplasm
messages: Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

216946:STURON RS05860
gene id: 216946:STURON_RS05860
uniprot id: A0A0K1P6F3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Membrane

216946:STURON RS00370
gene id: 216946:STURON_RS00370
uniprot id: A0A0K1P5W9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Membrane

216946:STURON RS04570
gene id: 216946:STURON_RS04570
uniprot id: A0A0K1P774
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

216946:STURON RS03365
gene id: 216946:STURON_RS03365
uniprot id: A0A0K1P6P9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

216946:STURON RS05260
gene id: 216946:STURON_RS05260
uniprot id: A0A0K1P7K6
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

216946:STURON RS04645
gene id: 216946:STURON_RS04645
uniprot id: A0A0K1P789
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm
messages: Homodimer.

216946:STURON RS01345
gene id: 216946:STURON_RS01345
uniprot id: A0A0K1P5P6
names: Subcellular Location Annotation
messages: Membrane

216946:STURON RS00985
gene id: 216946:STURON_RS00985
uniprot id: A0A0K1P528
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

216946:STURON RS01425
gene id: 216946:STURON_RS01425
uniprot id: A0A0K1P5E5
names: Similarity
names: Subunit
messages: Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.
messages: Homodimer.

216946:STURON RS05500
gene id: 216946:STURON_RS05500
uniprot id: A0A0K1P8T8
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.

216946:STURON RS00760
gene id: 216946:STURON_RS00760
uniprot id: A0A0K1P520
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

216946:STURON RS03665
gene id: 216946:STURON_RS03665
uniprot id: A0A0K1P6K2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family. NanA subfamily.
messages: Cytoplasm
messages: Homotetramer.

216946:STURON RS03590
gene id: 216946:STURON_RS03590
uniprot id: A0A0K1P6I9
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

216946:STURON RS04725
gene id: 216946:STURON_RS04725
uniprot id: A0A0K1P7J6
names: Subcellular Location Annotation
messages: Membrane

216946:STURON RS01375
gene id: 216946:STURON_RS01375
uniprot id: A0A0K1P5D5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell membrane
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

216946:STURON RS00395
gene id: 216946:STURON_RS00395
uniprot id: A0A0K1P4V8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

216946:STURON RS00305
gene id: 216946:STURON_RS00305
uniprot id: A0A0K1P563
names: Subcellular Location Annotation
messages: Membrane

216946:STURON RS05325
gene id: 216946:STURON_RS05325
uniprot id: A0A0K1P8Q3
names: Similarity
messages: Belongs to the peptidase M17 family.

216946:STURON RS00070
gene id: 216946:STURON_RS00070
uniprot id: A0A0K1P4P9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

216946:STURON RS00320
gene id: 216946:STURON_RS00320
uniprot id: A0A0K1P5W0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

216946:STURON RS04130
gene id: 216946:STURON_RS04130
uniprot id: A0A0K1P840
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

216946:STURON RS05575
gene id: 216946:STURON_RS05575
uniprot id: A0A0K1P8V4
names: Similarity
messages: Belongs to the phosphate acetyltransferase and butyryltransferase family.

216946:STURON RS04260
gene id: 216946:STURON_RS04260
uniprot id: A0A0K1P6Y0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Membrane

216946:STURON RS03360
gene id: 216946:STURON_RS03360
uniprot id: A0A0K1P6F9
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

216946:STURON RS01280
gene id: 216946:STURON_RS01280
uniprot id: A0A0K1P586
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Tetramer of two alpha and two beta subunits.

216946:STURON RS00050
gene id: 216946:STURON_RS00050
uniprot id: A0A0K1P517
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

216946:STURON RS04950
gene id: 216946:STURON_RS04950
uniprot id: A0A0K1P7N4
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the ferredoxin--NADP reductase type 2 family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

216946:STURON RS02615
gene id: 216946:STURON_RS02615
uniprot id: A0A0K1P5Z7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsY family.
messages: Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
messages: Cell membrane
messages: Probably interacts with PlsX.

216946:STURON RS01275
gene id: 216946:STURON_RS01275
uniprot id: A0A0K1P5A6
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

216946:STURON RS04615
gene id: 216946:STURON_RS04615
uniprot id: A0A0K1P8B2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

216946:STURON RS01940
gene id: 216946:STURON_RS01940
uniprot id: A0A0K1P6U4
names: Subcellular Location Annotation
messages: Membrane

216946:STURON RS04425
gene id: 216946:STURON_RS04425
uniprot id: A0A0K1P7E5
names: Function
names: Similarity
messages: Belongs to the PNP/MTAP phosphorylase family.
messages: The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.

216946:STURON RS03265
gene id: 216946:STURON_RS03265
uniprot id: A0A0K1P6N3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endonuclease Cas1 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas2 homodimer.

216946:STURON RS04495
gene id: 216946:STURON_RS04495
uniprot id: A0A0K1P759
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PPase family.
messages: Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
messages: Cytoplasm
messages: Homohexamer.

216946:STURON RS01520
gene id: 216946:STURON_RS01520
uniprot id: A0A0K1P5G2
names: Function
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.

216946:STURON RS01065
gene id: 216946:STURON_RS01065
uniprot id: A0A0K1P543
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsX family.
messages: Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
messages: Cytoplasm
messages: Homodimer. Probably interacts with PlsY.

216946:STURON RS05265
gene id: 216946:STURON_RS05265
uniprot id: A0A0K1P7H7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

216946:STURON RS02625
gene id: 216946:STURON_RS02625
uniprot id: A0A0K1P647
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0154 family.
messages: Membrane

216946:STURON RS03985
gene id: 216946:STURON_RS03985
uniprot id: A0A0K1P6W7
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

216946:STURON RS01760
gene id: 216946:STURON_RS01760
uniprot id: A0A0K1P5I1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

216946:STURON RS04430
gene id: 216946:STURON_RS04430
uniprot id: A0A0K1P740
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

216946:STURON RS05345
gene id: 216946:STURON_RS05345
uniprot id: A0A0K1P7J5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

216946:STURON RS00355
gene id: 216946:STURON_RS00355
uniprot id: A0A0K1P573
names: Function
names: Similarity
messages: Belongs to the WhiA family.
messages: Involved in cell division and chromosome segregation.

216946:STURON RS01105
gene id: 216946:STURON_RS01105
uniprot id: A0A0K1P5J0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

216946:STURON RS05145
gene id: 216946:STURON_RS05145
uniprot id: A0A0K1P7H3
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

216946:STURON RS01550
gene id: 216946:STURON_RS01550
uniprot id: A0A0K1P5T0
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

216946:STURON RS01950
gene id: 216946:STURON_RS01950
uniprot id: A0A0K1P602
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

216946:STURON RS00120
gene id: 216946:STURON_RS00120
uniprot id: A0A0K1P4R3
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

216946:STURON RS00460
gene id: 216946:STURON_RS00460
uniprot id: A0A0K1P4V9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.
messages: Belongs to the organic radical-activating enzymes family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm

216946:STURON RS04290
gene id: 216946:STURON_RS04290
uniprot id: A0A0K1P6Y6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

216946:STURON RS02180
gene id: 216946:STURON_RS02180
uniprot id: A0A0K1P5P3
names: Subcellular Location Annotation
messages: Membrane

216946:STURON RS02020
gene id: 216946:STURON_RS02020
uniprot id: A0A0K1P5N4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

216946:STURON RS01370
gene id: 216946:STURON_RS01370
uniprot id: A0A0K1P5Q1
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

216946:STURON RS02760
gene id: 216946:STURON_RS02760
uniprot id: A0A0K1P798
names: Similarity
messages: Belongs to the glycosyl hydrolase 32 family.

216946:STURON RS02925
gene id: 216946:STURON_RS02925
uniprot id: A0A0K1P6A2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

216946:STURON RS00130
gene id: 216946:STURON_RS00130
uniprot id: A0A0K1P4P1
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

216946:STURON RS04040
gene id: 216946:STURON_RS04040
uniprot id: A0A0K1P750
names: Similarity
messages: Belongs to the peptidase M17 family.

216946:STURON RS04120
gene id: 216946:STURON_RS04120
uniprot id: A0A0K1P6Z0
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

216946:STURON RS03200
gene id: 216946:STURON_RS03200
uniprot id: A0A0K1P6E5
names: Similarity
messages: Belongs to the glycosyl hydrolase 32 family.

216946:STURON RS02200
gene id: 216946:STURON_RS02200
uniprot id: A0A0K1P5W8
names: Subcellular Location Annotation
messages: Membrane

216946:STURON RS03115
gene id: 216946:STURON_RS03115
uniprot id: A0A0K1P690
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

216946:STURON RS05095
gene id: 216946:STURON_RS05095
uniprot id: A0A0K1P7G4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

216946:STURON RS00435
gene id: 216946:STURON_RS00435
uniprot id: A0A0K1P4V6
names: Cofactor
messages: Binds 1 zinc ion per subunit.

216946:STURON RS03965
gene id: 216946:STURON_RS03965
uniprot id: A0A0K1P6S8
names: Similarity
messages: Belongs to the glutamine synthetase family.

216946:STURON RS04185
gene id: 216946:STURON_RS04185
uniprot id: A0A0K1P6X9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.
messages: Homodimer.

216946:STURON RS02190
gene id: 216946:STURON_RS02190
uniprot id: A0A0K1P5R8
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

216946:STURON RS04855
gene id: 216946:STURON_RS04855
uniprot id: A0A0K1P786
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

216946:STURON RS00650
gene id: 216946:STURON_RS00650
uniprot id: A0A0K1P621
names: Similarity
messages: Belongs to the thioredoxin family.

216946:STURON RS04665
gene id: 216946:STURON_RS04665
uniprot id: A0A0K1P8C2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-3 family.
messages: Cytoplasm
messages: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.
messages: Monomer.

216946:STURON RS00315
gene id: 216946:STURON_RS00315
uniprot id: A0A0K1P4T8
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

216946:STURON RS00225
gene id: 216946:STURON_RS00225
uniprot id: A0A0K1P4S9
names: Similarity
messages: Belongs to the LacAB/RpiB family.

216946:STURON RS05225
gene id: 216946:STURON_RS05225
uniprot id: A0A0K1P7I9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

216946:STURON RS01300
gene id: 216946:STURON_RS01300
uniprot id: A0A0K1P5C3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MraZ family.
messages: Forms oligomers.
messages: nucleoid

216946:STURON RS04305
gene id: 216946:STURON_RS04305
uniprot id: A0A0K1P7C3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

216946:STURON RS02025
gene id: 216946:STURON_RS02025
uniprot id: A0A0K1P615
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp).
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

216946:STURON RS05510
gene id: 216946:STURON_RS05510
uniprot id: A0A0K1P7Y2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

216946:STURON RS01710
gene id: 216946:STURON_RS01710
uniprot id: A0A0K1P5H4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Membrane

216946:STURON RS03245
gene id: 216946:STURON_RS03245
uniprot id: A0A0K1P6F5
names: Subcellular Location Annotation
messages: Membrane

216946:STURON RS00350
gene id: 216946:STURON_RS00350
uniprot id: A0A0K1P4V2
names: Similarity
messages: Belongs to the Lgt family.

216946:STURON RS05580
gene id: 216946:STURON_RS05580
uniprot id: A0A0K1P7Q4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Mg(2+). Can also accept Mn(2+).

216946:STURON RS04210
gene id: 216946:STURON_RS04210
uniprot id: A0A0K1P6Y4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

216946:STURON RS04005
gene id: 216946:STURON_RS04005
uniprot id: A0A0K1P745
names: Function
names: Similarity
messages: Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily.
messages: Regulates the transcription of the pyrimidine nucleotide (pyr) operon in response to exogenous pyrimidines.

216946:STURON RS05280
gene id: 216946:STURON_RS05280
uniprot id: A0A0K1P7U3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

216946:STURON RS05160
gene id: 216946:STURON_RS05160
uniprot id: A0A0K1P7F8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

216946:STURON RS02060
gene id: 216946:STURON_RS02060
uniprot id: A0A0K1P5M3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Also exhibits azoreductase activity. Catalyzes the reductive cleavage of the azo bond in aromatic azo compounds to the corresponding amines.
messages: Belongs to the azoreductase type 1 family.
messages: Binds 1 FMN per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Quinone reductase that provides resistance to thiol-specific stress caused by electrophilic quinones.

216946:STURON RS00290
gene id: 216946:STURON_RS00290
uniprot id: A0A0K1P4T1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

216946:STURON RS04610
gene id: 216946:STURON_RS04610
uniprot id: A0A0K1P739
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

216946:STURON RS02460
gene id: 216946:STURON_RS02460
uniprot id: A0A0K1P738
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

216946:STURON RS01130
gene id: 216946:STURON_RS01130
uniprot id: A0A0K1P5J6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

216946:STURON RS01000
gene id: 216946:STURON_RS01000
uniprot id: A0A0K1P5G9
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.

216946:STURON RS02005
gene id: 216946:STURON_RS02005
uniprot id: A0A0K1P5T6
names: Subcellular Location Annotation
messages: Membrane

216946:STURON RS04465
gene id: 216946:STURON_RS04465
uniprot id: A0A0K1P884
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

216946:STURON RS04990
gene id: 216946:STURON_RS04990
uniprot id: A0A0K1P8I1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the BPG-independent phosphoglycerate mutase family.
messages: Binds 2 manganese ions per subunit.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: Monomer.

216946:STURON RS05270
gene id: 216946:STURON_RS05270
uniprot id: A0A0K1P8P2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

216946:STURON RS01500
gene id: 216946:STURON_RS01500
uniprot id: A0A0K1P5R9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Membrane

216946:STURON RS01135
gene id: 216946:STURON_RS01135
uniprot id: A0A0K1P588
names: Similarity
messages: Belongs to the CutC family.

216946:STURON RS01210
gene id: 216946:STURON_RS01210
uniprot id: A0A0K1P5K7
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

216946:STURON RS03670
gene id: 216946:STURON_RS03670
uniprot id: A0A0K1P7U1
names: Function
names: Similarity
messages: Belongs to the NanE family.
messages: Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P).

216946:STURON RS04460
gene id: 216946:STURON_RS04460
uniprot id: A0A0K1P715
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

216946:STURON RS01005
gene id: 216946:STURON_RS01005
uniprot id: A0A0K1P562
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.

216946:STURON RS02405
gene id: 216946:STURON_RS02405
uniprot id: A0A0K1P5W5
names: Similarity
messages: Belongs to the glycosyl hydrolase 32 family.

216946:STURON RS05285
gene id: 216946:STURON_RS05285
uniprot id: A0A0K1P7L0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

216946:STURON RS03240
gene id: 216946:STURON_RS03240
uniprot id: A0A0K1P6M8
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

216946:STURON RS05340
gene id: 216946:STURON_RS05340
uniprot id: A0A0K1P7L8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

216946:STURON RS04355
gene id: 216946:STURON_RS04355
uniprot id: A0A0K1P7D2
names: Subcellular Location Annotation
messages: Cytoplasm

216946:STURON RS05120
gene id: 216946:STURON_RS05120
uniprot id: A0A0K1P7G8
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

216946:STURON RS05000
gene id: 216946:STURON_RS05000
uniprot id: A0A0K1P7P4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

216946:STURON RS05465
gene id: 216946:STURON_RS05465
uniprot id: A0A0K1P7P1
names: Similarity
messages: Belongs to the ParB family.

216946:STURON RS04780
gene id: 216946:STURON_RS04780
uniprot id: A0A0K1P7A3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

216946:STURON RS04155
gene id: 216946:STURON_RS04155
uniprot id: A0A0K1P844
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

216946:STURON RS05205
gene id: 216946:STURON_RS05205
uniprot id: A0A0K1P7S9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

216946:STURON RS02455
gene id: 216946:STURON_RS02455
uniprot id: A0A0K1P5X5
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

216946:STURON RS00200
gene id: 216946:STURON_RS00200
uniprot id: A0A0K1P4S5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

216946:STURON RS00310
gene id: 216946:STURON_RS00310
uniprot id: A0A0K1P4S0
names: Similarity
messages: Belongs to the carbamate kinase family.

216946:STURON RS02965
gene id: 216946:STURON_RS02965
uniprot id: A0A0K1P7C5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Membrane

216946:STURON RS05315
gene id: 216946:STURON_RS05315
uniprot id: A0A0K1P7L4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M3B family.
messages: Binds 1 zinc ion.
messages: Has oligopeptidase activity and degrades a variety of small bioactive peptides.

216946:STURON RS04690
gene id: 216946:STURON_RS04690
uniprot id: A0A0K1P8C7
names: Similarity
messages: Belongs to the RutC family.

216946:STURON RS00815
gene id: 216946:STURON_RS00815
uniprot id: A0A0K1P5D0
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.

216946:STURON RS00580
gene id: 216946:STURON_RS00580
uniprot id: A0A0K1P5A9
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

216946:STURON RS01290
gene id: 216946:STURON_RS01290
uniprot id: A0A0K1P5B0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

216946:STURON RS00755
gene id: 216946:STURON_RS00755
uniprot id: A0A0K1P631
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

216946:STURON RS00525
gene id: 216946:STURON_RS00525
uniprot id: A0A0K1P4X6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).

216946:STURON RS02575
gene id: 216946:STURON_RS02575
uniprot id: A0A0K1P636
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseA family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

216946:STURON RS04905
gene id: 216946:STURON_RS04905
uniprot id: A0A0K1P796
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

216946:STURON RS05230
gene id: 216946:STURON_RS05230
uniprot id: A0A0K1P7T4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

216946:STURON RS01620
gene id: 216946:STURON_RS01620
uniprot id: A0A0K1P5H6
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

216946:STURON RS05240
gene id: 216946:STURON_RS05240
uniprot id: A0A0K1P7H1
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

216946:STURON RS02145
gene id: 216946:STURON_RS02145
uniprot id: A0A0K1P5Q9
names: Similarity
messages: Belongs to the NAPRTase family.

216946:STURON RS02550
gene id: 216946:STURON_RS02550
uniprot id: A0A0K1P632
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

216946:STURON RS02165
gene id: 216946:STURON_RS02165
uniprot id: A0A0K1P5R4
names: Subcellular Location Annotation
messages: Membrane

216946:STURON RS02185
gene id: 216946:STURON_RS02185
uniprot id: A0A0K1P6Z2
names: Function
names: Similarity
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.

216946:STURON RS00275
gene id: 216946:STURON_RS00275
uniprot id: A0A0K1P4T9
names: Similarity
messages: Belongs to the ATPase epsilon chain family.

216946:STURON RS02630
gene id: 216946:STURON_RS02630
uniprot id: A0A0K1P613
names: Similarity
names: Subunit
messages: Belongs to the transketolase family.
messages: Homodimer.

216946:STURON RS00485
gene id: 216946:STURON_RS00485
uniprot id: A0A0K1P4W6
names: Subcellular Location Annotation
messages: Cytoplasm

216946:STURON RS03585
gene id: 216946:STURON_RS03585
uniprot id: A0A0K1P6M6
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

216946:STURON RS02595
gene id: 216946:STURON_RS02595
uniprot id: A0A0K1P6B7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the AP endonuclease 2 family.
messages: Binds 3 Zn(2+) ions.
messages: Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate.

216946:STURON RS05250
gene id: 216946:STURON_RS05250
uniprot id: A0A0K1P7J4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

216946:STURON RS00010
gene id: 216946:STURON_RS00010
uniprot id: A0A0K1P5Q0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

216946:STURON RS05190
gene id: 216946:STURON_RS05190
uniprot id: A0A0K1P7G2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

216946:STURON RS00595
gene id: 216946:STURON_RS00595
uniprot id: A0A0K1P618
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Membrane

216946:STURON RS00890
gene id: 216946:STURON_RS00890
uniprot id: A0A0K1P656
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

216946:STURON RS01485
gene id: 216946:STURON_RS01485
uniprot id: A0A0K1P5D7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

216946:STURON RS05070
gene id: 216946:STURON_RS05070
uniprot id: A0A0K1P7G0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIIB subfamily.
messages: Cell inner membrane
messages: Mediates magnesium influx to the cytosol.
messages: Membrane

216946:STURON RS05490
gene id: 216946:STURON_RS05490
uniprot id: A0A0K1P7P7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

216946:STURON RS02495
gene id: 216946:STURON_RS02495
uniprot id: A0A0K1P6A1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LemA family.
messages: Membrane

216946:STURON RS02815
gene id: 216946:STURON_RS02815
uniprot id: A0A0K1P638
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Heptamer of 7 subunits arranged in a ring.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

216946:STURON RS00775
gene id: 216946:STURON_RS00775
uniprot id: A0A0K1P4Z4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

216946:STURON RS05435
gene id: 216946:STURON_RS05435
uniprot id: A0A0K1P7X2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Monomer.

216946:STURON RS02705
gene id: 216946:STURON_RS02705
uniprot id: A0A0K1P628
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.