216942:SLITO RS01840
gene id: 216942:SLITO_RS01840
uniprot id: A0A0K1W0Y6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

216942:SLITO RS01550
gene id: 216942:SLITO_RS01550
uniprot id: A0A0K1W186
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

216942:SLITO RS02190
gene id: 216942:SLITO_RS02190
uniprot id: A0A0K1W1K9
names: Subcellular Location Annotation
messages: Membrane

216942:SLITO RS00905
gene id: 216942:SLITO_RS00905
uniprot id: A0A0K1W155
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThiI family.
messages: Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.
messages: Cytoplasm

216942:SLITO RS00440
gene id: 216942:SLITO_RS00440
uniprot id: A0A0K1W0N5
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycyl radical enzyme (GRE) family. PFL subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

216942:SLITO RS04160
gene id: 216942:SLITO_RS04160
uniprot id: A0A0K1W2M3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

216942:SLITO RS05300
gene id: 216942:SLITO_RS05300
uniprot id: A0A0K1W384
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

216942:SLITO RS01845
gene id: 216942:SLITO_RS01845
uniprot id: A0A0K1W1D3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

216942:SLITO RS05660
gene id: 216942:SLITO_RS05660
uniprot id: A0A0K1W317
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

216942:SLITO RS01190
gene id: 216942:SLITO_RS01190
uniprot id: A0A0K1W129
names: Similarity
messages: Belongs to the lipase/esterase LIP3/BchO family.

216942:SLITO RS02195
gene id: 216942:SLITO_RS02195
uniprot id: A0A0K1W157
names: Function
names: Similarity
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.

216942:SLITO RS01340
gene id: 216942:SLITO_RS01340
uniprot id: A0A0K1W152
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

216942:SLITO RS01570
gene id: 216942:SLITO_RS01570
uniprot id: A0A0K1W1G9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

216942:SLITO RS05115
gene id: 216942:SLITO_RS05115
uniprot id: A0A0K1W350
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

216942:SLITO RS01170
gene id: 216942:SLITO_RS01170
uniprot id: A0A0K1W0N4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

216942:SLITO RS02300
gene id: 216942:SLITO_RS02300
uniprot id: A0A0K1W177
names: Subcellular Location Annotation
messages: Membrane

216942:SLITO RS01635
gene id: 216942:SLITO_RS01635
uniprot id: A0A0K1W0U6
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

216942:SLITO RS02090
gene id: 216942:SLITO_RS02090
uniprot id: A0A0K1W1J0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Also exhibits azoreductase activity. Catalyzes the reductive cleavage of the azo bond in aromatic azo compounds to the corresponding amines.
messages: Belongs to the azoreductase type 1 family.
messages: Binds 1 FMN per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Quinone reductase that provides resistance to thiol-specific stress caused by electrophilic quinones.

216942:SLITO RS00515
gene id: 216942:SLITO_RS00515
uniprot id: A0A0K1W0E1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).

216942:SLITO RS01540
gene id: 216942:SLITO_RS01540
uniprot id: A0A0K1W174
names: Similarity
messages: Belongs to the peptidase M24B family.

216942:SLITO RS05080
gene id: 216942:SLITO_RS05080
uniprot id: A0A0K1W2P4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

216942:SLITO RS02470
gene id: 216942:SLITO_RS02470
uniprot id: A0A0K1W1Y1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

216942:SLITO RS00745
gene id: 216942:SLITO_RS00745
uniprot id: A0A0K1W0U3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Membrane

216942:SLITO RS03385
gene id: 216942:SLITO_RS03385
uniprot id: A0A0K1W290
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

216942:SLITO RS03605
gene id: 216942:SLITO_RS03605
uniprot id: A0A0K1W1X9
names: Cofactor
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.

216942:SLITO RS02630
gene id: 216942:SLITO_RS02630
uniprot id: A0A0K1W1T7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsY family.
messages: Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Probably interacts with PlsX.

216942:SLITO RS01015
gene id: 216942:SLITO_RS01015
uniprot id: A0A0K1W173
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

216942:SLITO RS04035
gene id: 216942:SLITO_RS04035
uniprot id: A0A0K1W255
names: Caution
names: Similarity
messages: Belongs to the MsrB Met sulfoxide reductase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

216942:SLITO RS03055
gene id: 216942:SLITO_RS03055
uniprot id: A0A0K1W1L8
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

216942:SLITO RS00045
gene id: 216942:SLITO_RS00045
uniprot id: A0A0K1W039
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

216942:SLITO RS00955
gene id: 216942:SLITO_RS00955
uniprot id: A0A0K1W163
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

216942:SLITO RS00770
gene id: 216942:SLITO_RS00770
uniprot id: A0A0K1W0W3
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

216942:SLITO RS05930
gene id: 216942:SLITO_RS05930
uniprot id: A0A0K1W2X3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidine kinase family.
messages: Cytoplasm
messages: Homotetramer.

216942:SLITO RS02840
gene id: 216942:SLITO_RS02840
uniprot id: A0A0K1W1X2
names: Similarity
messages: Belongs to the glycosyl hydrolase 32 family.

216942:SLITO RS03590
gene id: 216942:SLITO_RS03590
uniprot id: A0A0K1W2L0
names: Similarity
messages: Belongs to the LacAB/RpiB family.

216942:SLITO RS04600
gene id: 216942:SLITO_RS04600
uniprot id: A0A0K1W2E5
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

216942:SLITO RS01355
gene id: 216942:SLITO_RS01355
uniprot id: A0A0K1W137
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

216942:SLITO RS03300
gene id: 216942:SLITO_RS03300
uniprot id: A0A0K1W1S7
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.

216942:SLITO RS03000
gene id: 216942:SLITO_RS03000
uniprot id: A0A0K1W1K8
names: Subcellular Location Annotation
messages: Membrane

216942:SLITO RS01000
gene id: 216942:SLITO_RS01000
uniprot id: A0A0K1W0K8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily.
messages: Cytoplasm
messages: Homodimer, may be a subunit of the RNA degradosome.

216942:SLITO RS03975
gene id: 216942:SLITO_RS03975
uniprot id: A0A0K1W2S9
names: Subcellular Location Annotation
messages: Membrane

216942:SLITO RS04285
gene id: 216942:SLITO_RS04285
uniprot id: A0A0K1W2P1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecU family.
messages: Cytoplasm

216942:SLITO RS02645
gene id: 216942:SLITO_RS02645
uniprot id: A0A0K1W1S8
names: Similarity
names: Subunit
messages: Belongs to the transketolase family.
messages: Homodimer.

216942:SLITO RS05100
gene id: 216942:SLITO_RS05100
uniprot id: A0A0K1W351
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

216942:SLITO RS03490
gene id: 216942:SLITO_RS03490
uniprot id: A0A0K1W2A7
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

216942:SLITO RS00765
gene id: 216942:SLITO_RS00765
uniprot id: A0A0K1W136
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

216942:SLITO RS03575
gene id: 216942:SLITO_RS03575
uniprot id: A0A0K1W1X8
names: Cofactor
messages: Binds 1 Mg(2+) ion per trimer.

216942:SLITO RS02505
gene id: 216942:SLITO_RS02505
uniprot id: A0A0K1W1B7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LemA family.
messages: Membrane

216942:SLITO RS03130
gene id: 216942:SLITO_RS03130
uniprot id: A0A0K1W1N3
names: Similarity
messages: Belongs to the peptidase M17 family.

216942:SLITO RS01625
gene id: 216942:SLITO_RS01625
uniprot id: A0A0K1W1A1
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

216942:SLITO RS03295
gene id: 216942:SLITO_RS03295
uniprot id: A0A0K1W1S6
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated Cas9 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9/crRNA/tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer; Cas9 is inactive in the absence of the 2 guide RNAs (gRNA). Cas9 recognizes the protospacer adjacent motif (PAM) in the CRISPR repeat sequences to help distinguish self versus nonself, as targets within the bacterial CRISPR locus do not have PAMs. PAM recognition is also required for catalytic activity.
messages: Has 2 endonuclease domains. The discontinuous RuvC-like domain cleaves the target DNA noncomplementary to crRNA while the HNH nuclease domain cleaves the target DNA complementary to crRNA.
messages: Monomer. Binds crRNA and tracrRNA.

216942:SLITO RS05595
gene id: 216942:SLITO_RS05595
uniprot id: A0A0K1W3D4
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.

216942:SLITO RS00160
gene id: 216942:SLITO_RS00160
uniprot id: A0A0K1W0Q9
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

216942:SLITO RS03290
gene id: 216942:SLITO_RS03290
uniprot id: A0A0K1W270
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endonuclease Cas1 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas2 homodimer.

216942:SLITO RS00050
gene id: 216942:SLITO_RS00050
uniprot id: A0A0K1W0F1
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

216942:SLITO RS01710
gene id: 216942:SLITO_RS01710
uniprot id: A0A0K1W0W2
names: Subcellular Location Annotation
messages: Membrane

216942:SLITO RS03945
gene id: 216942:SLITO_RS03945
uniprot id: A0A0K1W2I3
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

216942:SLITO RS04565
gene id: 216942:SLITO_RS04565
uniprot id: A0A0K1W2E0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-3 family.
messages: Cytoplasm
messages: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.
messages: Monomer.

216942:SLITO RS05670
gene id: 216942:SLITO_RS05670
uniprot id: A0A0K1W3F0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

216942:SLITO RS03115
gene id: 216942:SLITO_RS03115
uniprot id: A0A0K1W297
names: Cofactor
messages: Binds 1 Mg(2+) ion per trimer.

216942:SLITO RS05555
gene id: 216942:SLITO_RS05555
uniprot id: A0A0K1W3D6
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

216942:SLITO RS05575
gene id: 216942:SLITO_RS05575
uniprot id: A0A0K1W3K7
names: Subcellular Location Annotation
messages: Membrane

216942:SLITO RS00110
gene id: 216942:SLITO_RS00110
uniprot id: A0A0K1W0H8
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with bS18 to 16S ribosomal RNA.

216942:SLITO RS05040
gene id: 216942:SLITO_RS05040
uniprot id: A0A0K1W336
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

216942:SLITO RS04630
gene id: 216942:SLITO_RS04630
uniprot id: A0A0K1W2F0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Membrane

216942:SLITO RS03695
gene id: 216942:SLITO_RS03695
uniprot id: A0A0K1W2E3
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

216942:SLITO RS02570
gene id: 216942:SLITO_RS02570
uniprot id: A0A0K1W203
names: Similarity
messages: Belongs to the TlyA family.

216942:SLITO RS05715
gene id: 216942:SLITO_RS05715
uniprot id: A0A0K1W326
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Mg(2+). Can also accept Mn(2+).

216942:SLITO RS00480
gene id: 216942:SLITO_RS00480
uniprot id: A0A0K1W0S3
names: Similarity
names: Subunit
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.
messages: Tetramer of two alpha and two beta subunits.

216942:SLITO RS05600
gene id: 216942:SLITO_RS05600
uniprot id: A0A0K1W3L1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

216942:SLITO RS04960
gene id: 216942:SLITO_RS04960
uniprot id: A0A0K1W2L9
names: Caution
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

216942:SLITO RS00120
gene id: 216942:SLITO_RS00120
uniprot id: A0A0K1W054
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein bS6.

216942:SLITO RS00195
gene id: 216942:SLITO_RS00195
uniprot id: A0A0K1W0J6
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

216942:SLITO RS00215
gene id: 216942:SLITO_RS00215
uniprot id: A0A0K1W0R9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

216942:SLITO RS05105
gene id: 216942:SLITO_RS05105
uniprot id: A0A0K1W2P9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

216942:SLITO RS02695
gene id: 216942:SLITO_RS02695
uniprot id: A0A0K1W1U0
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvB family.
messages: Cytoplasm
messages: Has 3 domains, the large (RuvB-L) and small ATPase (RuvB-S) domains and the C-terminal head (RuvB-H) domain. The head domain binds DNA, while the ATPase domains jointly bind ATP, ADP or are empty depending on the state of the subunit in the translocation cycle. During a single DNA translocation step the structure of each domain remains the same, but their relative positions change.
messages: Homohexamer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time. Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange. Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration. The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration. Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.

216942:SLITO RS05270
gene id: 216942:SLITO_RS05270
uniprot id: A0A0K1W3F3
names: Similarity
messages: Belongs to the peptidase M17 family.

216942:SLITO RS01900
gene id: 216942:SLITO_RS01900
uniprot id: A0A0K1W1N1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

216942:SLITO RS04975
gene id: 216942:SLITO_RS04975
uniprot id: A0A0K1W324
names: Similarity
messages: Belongs to the SAICAR synthetase family.

216942:SLITO RS03890
gene id: 216942:SLITO_RS03890
uniprot id: A0A0K1W229
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.

216942:SLITO RS00210
gene id: 216942:SLITO_RS00210
uniprot id: A0A0K1W0I4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

216942:SLITO RS01295
gene id: 216942:SLITO_RS01295
uniprot id: A0A0K1W148
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

216942:SLITO RS03165
gene id: 216942:SLITO_RS03165
uniprot id: A0A0K1W2A9
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

216942:SLITO RS03875
gene id: 216942:SLITO_RS03875
uniprot id: A0A0K1W2Q9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the OMP decarboxylase family. Type 1 subfamily.
messages: Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
messages: Homodimer.

216942:SLITO RS00775
gene id: 216942:SLITO_RS00775
uniprot id: A0A0K1W0H2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LDH/MDH superfamily. LDH family.
messages: Catalyzes the conversion of lactate to pyruvate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

216942:SLITO RS00630
gene id: 216942:SLITO_RS00630
uniprot id: A0A0K1W122
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

216942:SLITO RS03195
gene id: 216942:SLITO_RS03195
uniprot id: A0A0K1W242
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.

216942:SLITO RS00070
gene id: 216942:SLITO_RS00070
uniprot id: A0A0K1W044
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

216942:SLITO RS03580
gene id: 216942:SLITO_RS03580
uniprot id: A0A0K1W1X4
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

216942:SLITO RS00430
gene id: 216942:SLITO_RS00430
uniprot id: A0A0K1W0B2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

216942:SLITO RS01535
gene id: 216942:SLITO_RS01535
uniprot id: A0A0K1W0S7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

216942:SLITO RS03860
gene id: 216942:SLITO_RS03860
uniprot id: A0A0K1W227
names: Similarity
messages: Belongs to the glutamine synthetase family.

216942:SLITO RS01650
gene id: 216942:SLITO_RS01650
uniprot id: A0A0K1W1A6
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

216942:SLITO RS04515
gene id: 216942:SLITO_RS04515
uniprot id: A0A0K1W2D2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

216942:SLITO RS04170
gene id: 216942:SLITO_RS04170
uniprot id: A0A0K1W269
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

216942:SLITO RS02305
gene id: 216942:SLITO_RS02305
uniprot id: A0A0K1W180
names: Similarity
messages: Belongs to the glycosyl hydrolase 32 family.

216942:SLITO RS04950
gene id: 216942:SLITO_RS04950
uniprot id: A0A0K1W319
names: Similarity
messages: Belongs to the GARS family.

216942:SLITO RS05000
gene id: 216942:SLITO_RS05000
uniprot id: A0A0K1W328
names: Subcellular Location Annotation
messages: Membrane

216942:SLITO RS01465
gene id: 216942:SLITO_RS01465
uniprot id: A0A0K1W164
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.

216942:SLITO RS00185
gene id: 216942:SLITO_RS00185
uniprot id: A0A0K1W0H9
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

216942:SLITO RS05745
gene id: 216942:SLITO_RS05745
uniprot id: A0A0K1W3G5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RnpA family.
messages: Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.
messages: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.

216942:SLITO RS01485
gene id: 216942:SLITO_RS01485
uniprot id: A0A0K1W0S2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

216942:SLITO RS00490
gene id: 216942:SLITO_RS00490
uniprot id: A0A0K1W0D7
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

216942:SLITO RS00400
gene id: 216942:SLITO_RS00400
uniprot id: A0A0K1W0P1
names: Function
names: Similarity
messages: Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.
messages: Belongs to the organic radical-activating enzymes family.

216942:SLITO RS01995
gene id: 216942:SLITO_RS01995
uniprot id: A0A0K1W114
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

216942:SLITO RS01760
gene id: 216942:SLITO_RS01760
uniprot id: A0A0K1W0X1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

216942:SLITO RS05730
gene id: 216942:SLITO_RS05730
uniprot id: A0A0K1W3H4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
messages: Binds 1 potassium ion per subunit.
messages: Cytoplasm
messages: Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

216942:SLITO RS05045
gene id: 216942:SLITO_RS05045
uniprot id: A0A0K1W3A8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

216942:SLITO RS05750
gene id: 216942:SLITO_RS05750
uniprot id: A0A0K1W3P0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

216942:SLITO RS01005
gene id: 216942:SLITO_RS01005
uniprot id: A0A0K1W0K5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

216942:SLITO RS04820
gene id: 216942:SLITO_RS04820
uniprot id: A0A0K1W2Z2
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the ferredoxin--NADP reductase type 2 family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

216942:SLITO RS02525
gene id: 216942:SLITO_RS02525
uniprot id: A0A0K1W1R6
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

216942:SLITO RS00530
gene id: 216942:SLITO_RS00530
uniprot id: A0A0K1W0T3
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

216942:SLITO RS00525
gene id: 216942:SLITO_RS00525
uniprot id: A0A0K1W108
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

216942:SLITO RS02155
gene id: 216942:SLITO_RS02155
uniprot id: A0A0K1W1J2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
messages: Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
messages: Cytoplasm

216942:SLITO RS00230
gene id: 216942:SLITO_RS00230
uniprot id: A0A0K1W074
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
messages: Allosterically activated by GTP.
messages: Belongs to the UPRTase family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.
messages: Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.

216942:SLITO RS00245
gene id: 216942:SLITO_RS00245
uniprot id: A0A0K1W076
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

216942:SLITO RS01460
gene id: 216942:SLITO_RS01460
uniprot id: A0A0K1W0R7
names: Subcellular Location Annotation
messages: Membrane

216942:SLITO RS03985
gene id: 216942:SLITO_RS03985
uniprot id: A0A0K1W248
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

216942:SLITO RS01620
gene id: 216942:SLITO_RS01620
uniprot id: A0A0K1W1H8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer.

216942:SLITO RS01090
gene id: 216942:SLITO_RS01090
uniprot id: A0A0K1W0Z3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsX family.
messages: Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
messages: Cytoplasm
messages: Homodimer. Probably interacts with PlsY.

216942:SLITO RS02565
gene id: 216942:SLITO_RS02565
uniprot id: A0A0K1W1R5
names: Similarity
messages: Belongs to the DNA polymerase type-Y family.

216942:SLITO RS05130
gene id: 216942:SLITO_RS05130
uniprot id: A0A0K1W2Q4
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

216942:SLITO RS03125
gene id: 216942:SLITO_RS03125
uniprot id: A0A0K1W1N0
names: Subcellular Location Annotation
messages: Membrane

216942:SLITO RS02365
gene id: 216942:SLITO_RS02365
uniprot id: A0A0K1W1W1
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

216942:SLITO RS04640
gene id: 216942:SLITO_RS04640
uniprot id: A0A0K1W338
names: Similarity
messages: Belongs to the pyruvate kinase family.

216942:SLITO RS02330
gene id: 216942:SLITO_RS02330
uniprot id: A0A0K1W185
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

216942:SLITO RS04995
gene id: 216942:SLITO_RS04995
uniprot id: A0A0K1W399
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

216942:SLITO RS02580
gene id: 216942:SLITO_RS02580
uniprot id: A0A0K1W1D2
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Homodimer.

216942:SLITO RS01020
gene id: 216942:SLITO_RS01020
uniprot id: A0A0K1W100
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.

216942:SLITO RS02045
gene id: 216942:SLITO_RS02045
uniprot id: A0A0K1W128
names: Subcellular Location Annotation
messages: Membrane

216942:SLITO RS02725
gene id: 216942:SLITO_RS02725
uniprot id: A0A0K1W1F8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

216942:SLITO RS01345
gene id: 216942:SLITO_RS01345
uniprot id: A0A0K1W0Q4
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

216942:SLITO RS01555
gene id: 216942:SLITO_RS01555
uniprot id: A0A0K1W0T5
names: Caution
names: Function
names: Similarity
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

216942:SLITO RS06080
gene id: 216942:SLITO_RS06080
uniprot id: A0A0K1W0T9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Membrane

216942:SLITO RS02735
gene id: 216942:SLITO_RS02735
uniprot id: A0A0K1W1U6
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

216942:SLITO RS00015
gene id: 216942:SLITO_RS00015
uniprot id: A0A0K1W034
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA which binds and tethers DNA polymerases and other proteins to the DNA. The DNA replisome complex has a single clamp-loading complex (3 tau and 1 each of delta, delta', psi and chi subunits) which binds 3 Pol III cores (1 core on the leading strand and 2 on the lagging strand) each with a beta sliding clamp dimer. Additional proteins in the replisome are other copies of gamma, psi and chi, Ssb, DNA helicase and RNA primase.

216942:SLITO RS01795
gene id: 216942:SLITO_RS01795
uniprot id: A0A0K1W1L2
names: Subcellular Location Annotation
messages: Membrane

216942:SLITO RS05305
gene id: 216942:SLITO_RS05305
uniprot id: A0A0K1W2U4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

216942:SLITO RS04430
gene id: 216942:SLITO_RS04430
uniprot id: A0A0K1W2R5
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Inhibited by UTP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

216942:SLITO RS01800
gene id: 216942:SLITO_RS01800
uniprot id: A0A0K1W1D4
names: Subcellular Location Annotation
messages: Membrane

216942:SLITO RS00895
gene id: 216942:SLITO_RS00895
uniprot id: A0A0K1W0I8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

216942:SLITO RS00350
gene id: 216942:SLITO_RS00350
uniprot id: A0A0K1W098
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.
messages: Belongs to the RNR ribonuclease family. RNase R subfamily.
messages: Cytoplasm

216942:SLITO RS02495
gene id: 216942:SLITO_RS02495
uniprot id: A0A0K1W1Y6
names: Subcellular Location Annotation
messages: cytosol

216942:SLITO RS05110
gene id: 216942:SLITO_RS05110
uniprot id: A0A0K1W2Q0
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

216942:SLITO RS01275
gene id: 216942:SLITO_RS01275
uniprot id: A0A0K1W0P9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

216942:SLITO RS01910
gene id: 216942:SLITO_RS01910
uniprot id: A0A0K1W101
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

216942:SLITO RS03315
gene id: 216942:SLITO_RS03315
uniprot id: A0A0K1W275
names: Cofactor
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.

216942:SLITO RS01825
gene id: 216942:SLITO_RS01825
uniprot id: A0A0K1W1L6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

216942:SLITO RS01080
gene id: 216942:SLITO_RS01080
uniprot id: A0A0K1W0M1
names: Subcellular Location Annotation
messages: Membrane

216942:SLITO RS05135
gene id: 216942:SLITO_RS05135
uniprot id: A0A0K1W2Q5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

216942:SLITO RS00425
gene id: 216942:SLITO_RS00425
uniprot id: A0A0K1W0P6
names: Subcellular Location Annotation
messages: Membrane

216942:SLITO RS00330
gene id: 216942:SLITO_RS00330
uniprot id: A0A0K1W0L3
names: Function
names: Similarity
messages: Belongs to the WhiA family.
messages: Involved in cell division and chromosome segregation.

216942:SLITO RS02055
gene id: 216942:SLITO_RS02055
uniprot id: A0A0K1W1H2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

216942:SLITO RS01590
gene id: 216942:SLITO_RS01590
uniprot id: A0A0K1W184
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial diacylglycerol kinase family.
messages: Membrane
messages: Mn(2+), Zn(2+), Cd(2+) and Co(2+) support activity to lesser extents.

216942:SLITO RS05505
gene id: 216942:SLITO_RS05505
uniprot id: A0A0K1W3C5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Monomer.

216942:SLITO RS05640
gene id: 216942:SLITO_RS05640
uniprot id: A0A0K1W310
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

216942:SLITO RS00200
gene id: 216942:SLITO_RS00200
uniprot id: A0A0K1W066
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

216942:SLITO RS05075
gene id: 216942:SLITO_RS05075
uniprot id: A0A0K1W347
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

216942:SLITO RS01380
gene id: 216942:SLITO_RS01380
uniprot id: A0A0K1W0Q8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

216942:SLITO RS04485
gene id: 216942:SLITO_RS04485
uniprot id: A0A0K1W2T0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

216942:SLITO RS04835
gene id: 216942:SLITO_RS04835
uniprot id: A0A0K1W2J0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

216942:SLITO RS00935
gene id: 216942:SLITO_RS00935
uniprot id: A0A0K1W0Y8
names: Function
names: Similarity
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.

216942:SLITO RS04300
gene id: 216942:SLITO_RS04300
uniprot id: A0A0K1W2P2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

216942:SLITO RS01075
gene id: 216942:SLITO_RS01075
uniprot id: A0A0K1W110
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

216942:SLITO RS00325
gene id: 216942:SLITO_RS00325
uniprot id: A0A0K1W093
names: Similarity
messages: Belongs to the Lgt family.

216942:SLITO RS03330
gene id: 216942:SLITO_RS03330
uniprot id: A0A0K1W272
names: Subcellular Location Annotation
messages: Membrane

216942:SLITO RS01375
gene id: 216942:SLITO_RS01375
uniprot id: A0A0K1W156
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MraZ family.
messages: Forms oligomers.
messages: nucleoid

216942:SLITO RS04390
gene id: 216942:SLITO_RS04390
uniprot id: A0A0K1W2R1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

216942:SLITO RS00880
gene id: 216942:SLITO_RS00880
uniprot id: A0A0K1W153
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

216942:SLITO RS01765
gene id: 216942:SLITO_RS01765
uniprot id: A0A0K1W1B9
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

216942:SLITO RS05055
gene id: 216942:SLITO_RS05055
uniprot id: A0A0K1W2N9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

216942:SLITO RS01255
gene id: 216942:SLITO_RS01255
uniprot id: A0A0K1W0P4
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

216942:SLITO RS04295
gene id: 216942:SLITO_RS04295
uniprot id: A0A0K1W289
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

216942:SLITO RS00640
gene id: 216942:SLITO_RS00640
uniprot id: A0A0K1W0G0
names: Similarity
messages: Belongs to the thioredoxin family.

216942:SLITO RS04130
gene id: 216942:SLITO_RS04130
uniprot id: A0A0K1W2L8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Membrane

216942:SLITO RS05030
gene id: 216942:SLITO_RS05030
uniprot id: A0A0K1W2N2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

216942:SLITO RS00965
gene id: 216942:SLITO_RS00965
uniprot id: A0A0K1W0K4
names: Subcellular Location Annotation
messages: Membrane

216942:SLITO RS01940
gene id: 216942:SLITO_RS01940
uniprot id: A0A0K1W106
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
messages: Could methylate the ribose at the nucleotide 34 wobble position in tRNA.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

216942:SLITO RS05560
gene id: 216942:SLITO_RS05560
uniprot id: A0A0K1W2Z6
names: Similarity
messages: Belongs to the ParB family.

216942:SLITO RS01060
gene id: 216942:SLITO_RS01060
uniprot id: A0A0K1W0L5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

216942:SLITO RS00405
gene id: 216942:SLITO_RS00405
uniprot id: A0A0K1W0A7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

216942:SLITO RS02360
gene id: 216942:SLITO_RS02360
uniprot id: A0A0K1W1N2
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

216942:SLITO RS00125
gene id: 216942:SLITO_RS00125
uniprot id: A0A0K1W0G7
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

216942:SLITO RS00090
gene id: 216942:SLITO_RS00090
uniprot id: A0A0K1W045
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

216942:SLITO RS03415
gene id: 216942:SLITO_RS03415
uniprot id: A0A0K1W1U8
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

216942:SLITO RS00315
gene id: 216942:SLITO_RS00315
uniprot id: A0A0K1W0M5
names: Similarity
messages: Belongs to the Lgt family.

216942:SLITO RS01585
gene id: 216942:SLITO_RS01585
uniprot id: A0A0K1W0T7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

216942:SLITO RS04855
gene id: 216942:SLITO_RS04855
uniprot id: A0A0K1W2Z9
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily.
messages: Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

216942:SLITO RS04635
gene id: 216942:SLITO_RS04635
uniprot id: A0A0K1W2V7
names: Subcellular Location Annotation
messages: Membrane

216942:SLITO RS03100
gene id: 216942:SLITO_RS03100
uniprot id: A0A0K1W1M5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nicotinamide ribonucleoside (NR) uptake permease (TC 4.B.1) family.
messages: Membrane

216942:SLITO RS04690
gene id: 216942:SLITO_RS04690
uniprot id: A0A0K1W2F9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PA-phosphatase related phosphoesterase family.
messages: Membrane

216942:SLITO RS04175
gene id: 216942:SLITO_RS04175
uniprot id: A0A0K1W2M2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

216942:SLITO RS05025
gene id: 216942:SLITO_RS05025
uniprot id: A0A0K1W333
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

216942:SLITO RS04465
gene id: 216942:SLITO_RS04465
uniprot id: A0A0K1W2C3
names: Subcellular Location Annotation
messages: Membrane

216942:SLITO RS03510
gene id: 216942:SLITO_RS03510
uniprot id: A0A0K1W2J7
names: Subcellular Location Annotation
messages: Membrane

216942:SLITO RS00320
gene id: 216942:SLITO_RS00320
uniprot id: A0A0K1W092
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Homodimer.

216942:SLITO RS04670
gene id: 216942:SLITO_RS04670
uniprot id: A0A0K1W2F5
names: Similarity
messages: Belongs to the pyruvate kinase family.

216942:SLITO RS00095
gene id: 216942:SLITO_RS00095
uniprot id: A0A0K1W049
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

216942:SLITO RS00960
gene id: 216942:SLITO_RS00960
uniprot id: A0A0K1W0Z1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Monomer.

216942:SLITO RS01455
gene id: 216942:SLITO_RS01455
uniprot id: A0A0K1W0S1
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

216942:SLITO RS05175
gene id: 216942:SLITO_RS05175
uniprot id: A0A0K1W362
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M3B family.
messages: Binds 1 zinc ion.
messages: Has oligopeptidase activity and degrades a variety of small bioactive peptides.

216942:SLITO RS05155
gene id: 216942:SLITO_RS05155
uniprot id: A0A0K1W2R0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

216942:SLITO RS05020
gene id: 216942:SLITO_RS05020
uniprot id: A0A0K1W3A2
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

216942:SLITO RS02825
gene id: 216942:SLITO_RS02825
uniprot id: A0A0K1W250
names: Similarity
messages: Belongs to the glycosyl hydrolase 32 family.

216942:SLITO RS04990
gene id: 216942:SLITO_RS04990
uniprot id: A0A0K1W325
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

216942:SLITO RS04865
gene id: 216942:SLITO_RS04865
uniprot id: A0A0K1W2J6
names: Similarity
messages: Belongs to the formate--tetrahydrofolate ligase family.

216942:SLITO RS03720
gene id: 216942:SLITO_RS03720
uniprot id: A0A0K1W202
names: Subcellular Location Annotation
messages: cytosol

216942:SLITO RS00260
gene id: 216942:SLITO_RS00260
uniprot id: A0A0K1W0T0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

216942:SLITO RS05485
gene id: 216942:SLITO_RS05485
uniprot id: A0A0K1W2X9
names: Cofactor
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.

216942:SLITO RS03805
gene id: 216942:SLITO_RS03805
uniprot id: A0A0K1W2F7
names: Subcellular Location Annotation
messages: Membrane

216942:SLITO RS04965
gene id: 216942:SLITO_RS04965
uniprot id: A0A0K1W320
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

216942:SLITO RS03455
gene id: 216942:SLITO_RS03455
uniprot id: A0A0K1W2A2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

216942:SLITO RS03190
gene id: 216942:SLITO_RS03190
uniprot id: A0A0K1W2B6
names: Subcellular Location Annotation
messages: Membrane

216942:SLITO RS05585
gene id: 216942:SLITO_RS05585
uniprot id: A0A0K1W302
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

216942:SLITO RS00295
gene id: 216942:SLITO_RS00295
uniprot id: A0A0K1W086
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

216942:SLITO RS02060
gene id: 216942:SLITO_RS02060
uniprot id: A0A0K1W1Q8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp).
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

216942:SLITO RS04050
gene id: 216942:SLITO_RS04050
uniprot id: A0A0K1W254
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

216942:SLITO RS00355
gene id: 216942:SLITO_RS00355
uniprot id: A0A0K1W0L8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

216942:SLITO RS04125
gene id: 216942:SLITO_RS04125
uniprot id: A0A0K1W2V1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmG family. TrmFO subfamily.
messages: Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs.
messages: Cytoplasm

216942:SLITO RS04075
gene id: 216942:SLITO_RS04075
uniprot id: A0A0K1W2K9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

216942:SLITO RS04210
gene id: 216942:SLITO_RS04210
uniprot id: A0A0K1W2W6
names: Subcellular Location Annotation
messages: Cytoplasm

216942:SLITO RS00900
gene id: 216942:SLITO_RS00900
uniprot id: A0A0K1W0W4
names: Subcellular Location Annotation
messages: Membrane

216942:SLITO RS05490
gene id: 216942:SLITO_RS05490
uniprot id: A0A0K1W2X8
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

216942:SLITO RS04325
gene id: 216942:SLITO_RS04325
uniprot id: A0A0K1W2P6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

216942:SLITO RS04870
gene id: 216942:SLITO_RS04870
uniprot id: A0A0K1W301
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

216942:SLITO RS04675
gene id: 216942:SLITO_RS04675
uniprot id: A0A0K1W2W2
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by ADP and other diphosphonucleosides, and allosterically inhibited by phosphoenolpyruvate.
messages: Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Prokaryotic clade 'B1' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

216942:SLITO RS01990
gene id: 216942:SLITO_RS01990
uniprot id: A0A0K1W118
names: Subcellular Location Annotation
messages: Membrane

216942:SLITO RS05160
gene id: 216942:SLITO_RS05160
uniprot id: A0A0K1W2R2
names: Subcellular Location Annotation
messages: Membrane

216942:SLITO RS04770
gene id: 216942:SLITO_RS04770
uniprot id: A0A0K1W2H6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 3 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).
messages: Consists of three domains: the N-terminal catalytic domain, the anticodon-binding domain and the C-terminal extension.
messages: Cytoplasm
messages: Homodimer.

216942:SLITO RS00285
gene id: 216942:SLITO_RS00285
uniprot id: A0A0K1W0T6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

216942:SLITO RS00235
gene id: 216942:SLITO_RS00235
uniprot id: A0A0K1W0S5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase A chain family.
messages: Membrane

216942:SLITO RS04510
gene id: 216942:SLITO_RS04510
uniprot id: A0A0K1W2T5
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

216942:SLITO RS04700
gene id: 216942:SLITO_RS04700
uniprot id: A0A0K1W2W7
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

216942:SLITO RS04685
gene id: 216942:SLITO_RS04685
uniprot id: A0A0K1W2W5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

216942:SLITO RS04155
gene id: 216942:SLITO_RS04155
uniprot id: A0A0K1W2V6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily.
messages: Cytoplasm
messages: Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity.

216942:SLITO RS00345
gene id: 216942:SLITO_RS00345
uniprot id: A0A0K1W097
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Membrane

216942:SLITO RS05150
gene id: 216942:SLITO_RS05150
uniprot id: A0A0K1W359
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

216942:SLITO RS01500
gene id: 216942:SLITO_RS01500
uniprot id: A0A0K1W181
names: Similarity
names: Subunit
messages: Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.
messages: Homodimer.

216942:SLITO RS01450
gene id: 216942:SLITO_RS01450
uniprot id: A0A0K1W171
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell membrane
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

216942:SLITO RS02120
gene id: 216942:SLITO_RS02120
uniprot id: A0A0K1W144
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 2 subfamily.
messages: Cell membrane
messages: Heterotetramer composed of ParC and ParE.
messages: Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.

216942:SLITO RS02335
gene id: 216942:SLITO_RS02335
uniprot id: A0A0K1W1M7
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

216942:SLITO RS04020
gene id: 216942:SLITO_RS04020
uniprot id: A0A0K1W2J8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

216942:SLITO RS04310
gene id: 216942:SLITO_RS04310
uniprot id: A0A0K1W2P7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

216942:SLITO RS05095
gene id: 216942:SLITO_RS05095
uniprot id: A0A0K1W3B8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

216942:SLITO RS05050
gene id: 216942:SLITO_RS05050
uniprot id: A0A0K1W342
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis. Some bacteria have evolved a zinc-coordinating structure that stabilizes the LID domain.
messages: Cytoplasm
messages: Monomer.

216942:SLITO RS00130
gene id: 216942:SLITO_RS00130
uniprot id: A0A0K1W0Q5
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity.

216942:SLITO RS01565
gene id: 216942:SLITO_RS01565
uniprot id: A0A0K1W179
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-C family. PolC subfamily.
messages: Cytoplasm
messages: Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

216942:SLITO RS01445
gene id: 216942:SLITO_RS01445
uniprot id: A0A0K1W1E9
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

216942:SLITO RS00010
gene id: 216942:SLITO_RS00010
uniprot id: A0A0K1W030
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

216942:SLITO RS00415
gene id: 216942:SLITO_RS00415
uniprot id: A0A0K1W0M9
names: Cofactor
messages: Binds 1 zinc ion per subunit.

216942:SLITO RS03585
gene id: 216942:SLITO_RS03585
uniprot id: A0A0K1W2B9
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

216942:SLITO RS00205
gene id: 216942:SLITO_RS00205
uniprot id: A0A0K1W069
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

216942:SLITO RS01545
gene id: 216942:SLITO_RS01545
uniprot id: A0A0K1W1G4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.

216942:SLITO RS01560
gene id: 216942:SLITO_RS01560
uniprot id: A0A0K1W0T2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

216942:SLITO RS04365
gene id: 216942:SLITO_RS04365
uniprot id: A0A0K1W2Q8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

216942:SLITO RS03325
gene id: 216942:SLITO_RS03325
uniprot id: A0A0K1W1T0
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

216942:SLITO RS04350
gene id: 216942:SLITO_RS04350
uniprot id: A0A0K1W2Q1
names: Similarity
messages: Belongs to the FBPase class 2 family.

216942:SLITO RS03925
gene id: 216942:SLITO_RS03925
uniprot id: A0A0K1W2R9
names: Similarity
messages: Belongs to the peptidase M17 family.

216942:SLITO RS05145
gene id: 216942:SLITO_RS05145
uniprot id: A0A0K1W3C8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

216942:SLITO RS04575
gene id: 216942:SLITO_RS04575
uniprot id: A0A0K1W2U7
names: Similarity
messages: Belongs to the RutC family.

216942:SLITO RS04305
gene id: 216942:SLITO_RS04305
uniprot id: A0A0K1W2Y1
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

216942:SLITO RS00820
gene id: 216942:SLITO_RS00820
uniprot id: A0A0K1W145
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 zinc ion per subunit.

216942:SLITO RS02585
gene id: 216942:SLITO_RS02585
uniprot id: A0A0K1W1D6
names: Similarity
messages: Belongs to the XseB family.

216942:SLITO RS04545
gene id: 216942:SLITO_RS04545
uniprot id: A0A0K1W2D8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm
messages: Homodimer.

216942:SLITO RS00475
gene id: 216942:SLITO_RS00475
uniprot id: A0A0K1W0Z8
names: Subcellular Location Annotation
messages: Cytoplasm

216942:SLITO RS01200
gene id: 216942:SLITO_RS01200
uniprot id: A0A0K1W0N7
names: Similarity
messages: Belongs to the CutC family.

216942:SLITO RS03885
gene id: 216942:SLITO_RS03885
uniprot id: A0A0K1W232
names: Caution
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

216942:SLITO RS05120
gene id: 216942:SLITO_RS05120
uniprot id: A0A0K1W3C3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

216942:SLITO RS01870
gene id: 216942:SLITO_RS01870
uniprot id: A0A0K1W1D7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

216942:SLITO RS02030
gene id: 216942:SLITO_RS02030
uniprot id: A0A0K1W1G7
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.

216942:SLITO RS03825
gene id: 216942:SLITO_RS03825
uniprot id: A0A0K1W221
names: Subcellular Location Annotation
messages: cytosol

216942:SLITO RS00660
gene id: 216942:SLITO_RS00660
uniprot id: A0A0K1W0G4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

216942:SLITO RS05705
gene id: 216942:SLITO_RS05705
uniprot id: A0A0K1W3G9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

216942:SLITO RS00190
gene id: 216942:SLITO_RS00190
uniprot id: A0A0K1W0R4
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

216942:SLITO RS01595
gene id: 216942:SLITO_RS01595
uniprot id: A0A0K1W1H4
names: Function
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.

216942:SLITO RS03900
gene id: 216942:SLITO_RS03900
uniprot id: A0A0K1W2R4
names: Function
names: Similarity
messages: Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily.
messages: Regulates the transcription of the pyrimidine nucleotide (pyr) operon in response to exogenous pyrimidines.

216942:SLITO RS00150
gene id: 216942:SLITO_RS00150
uniprot id: A0A0K1W059
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
messages: Cytoplasm
messages: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.

216942:SLITO RS05460
gene id: 216942:SLITO_RS05460
uniprot id: A0A0K1W2X4
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

216942:SLITO RS01720
gene id: 216942:SLITO_RS01720
uniprot id: A0A0K1W1J8
names: Cofactor
messages: Binds 1 Mg(2+) ion per trimer.

216942:SLITO RS00435
gene id: 216942:SLITO_RS00435
uniprot id: A0A0K1W0B3
names: Similarity
messages: In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.
messages: In the N-terminal section; belongs to the aldehyde dehydrogenase family.

216942:SLITO RS04905
gene id: 216942:SLITO_RS04905
uniprot id: A0A0K1W309
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

216942:SLITO RS00380
gene id: 216942:SLITO_RS00380
uniprot id: A0A0K1W0A2
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

216942:SLITO RS03940
gene id: 216942:SLITO_RS03940
uniprot id: A0A0K1W239
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

216942:SLITO RS01025
gene id: 216942:SLITO_RS01025
uniprot id: A0A0K1W0L2
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.

216942:SLITO RS04445
gene id: 216942:SLITO_RS04445
uniprot id: A0A0K1W2B8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

216942:SLITO RS03435
gene id: 216942:SLITO_RS03435
uniprot id: A0A0K1W1V4
names: Similarity
messages: Belongs to the glycosyl hydrolase 32 family.

216942:SLITO RS01695
gene id: 216942:SLITO_RS01695
uniprot id: A0A0K1W1J3
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

216942:SLITO RS00390
gene id: 216942:SLITO_RS00390
uniprot id: A0A0K1W0M3
names: Similarity
messages: Belongs to the PNP/UDP phosphorylase family.

216942:SLITO RS03990
gene id: 216942:SLITO_RS03990
uniprot id: A0A0K1W249
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

216942:SLITO RS05070
gene id: 216942:SLITO_RS05070
uniprot id: A0A0K1W3B2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

216942:SLITO RS00270
gene id: 216942:SLITO_RS00270
uniprot id: A0A0K1W081
names: Similarity
messages: Belongs to the ATPase epsilon chain family.

216942:SLITO RS05310
gene id: 216942:SLITO_RS05310
uniprot id: A0A0K1W2U2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

216942:SLITO RS03700
gene id: 216942:SLITO_RS03700
uniprot id: A0A0K1W200
names: Subcellular Location Annotation
messages: Membrane

216942:SLITO RS02200
gene id: 216942:SLITO_RS02200
uniprot id: A0A0K1W160
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

216942:SLITO RS04910
gene id: 216942:SLITO_RS04910
uniprot id: A0A0K1W2K5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIIB subfamily.
messages: Cell inner membrane
messages: Mediates magnesium influx to the cytosol.
messages: Membrane

216942:SLITO RS01245
gene id: 216942:SLITO_RS01245
uniprot id: A0A0K1W138
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

216942:SLITO RS00940
gene id: 216942:SLITO_RS00940
uniprot id: A0A0K1W0J9
names: Similarity
names: Subunit
messages: Belongs to the FPG family.
messages: Monomer.

216942:SLITO RS00115
gene id: 216942:SLITO_RS00115
uniprot id: A0A0K1W050
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

216942:SLITO RS03305
gene id: 216942:SLITO_RS03305
uniprot id: A0A0K1W267
names: Subcellular Location Annotation
messages: Membrane

216942:SLITO RS02350
gene id: 216942:SLITO_RS02350
uniprot id: A0A0K1W187
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta chain.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).

216942:SLITO RS00450
gene id: 216942:SLITO_RS00450
uniprot id: A0A0K1W0R8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.
messages: Belongs to the organic radical-activating enzymes family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm

216942:SLITO RS01470
gene id: 216942:SLITO_RS01470
uniprot id: A0A0K1W1F4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the RNase HII family. RnhC subfamily.
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

216942:SLITO RS04745
gene id: 216942:SLITO_RS04745
uniprot id: A0A0K1W2H1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

216942:SLITO RS02265
gene id: 216942:SLITO_RS02265
uniprot id: A0A0K1W1M4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

216942:SLITO RS02395
gene id: 216942:SLITO_RS02395
uniprot id: A0A0K1W1P9
names: Subcellular Location Annotation
messages: Membrane

216942:SLITO RS03870
gene id: 216942:SLITO_RS03870
uniprot id: A0A0K1W2G6
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

216942:SLITO RS03620
gene id: 216942:SLITO_RS03620
uniprot id: A0A0K1W2D1
names: Subcellular Location Annotation
messages: Membrane

216942:SLITO RS00780
gene id: 216942:SLITO_RS00780
uniprot id: A0A0K1W0H1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

216942:SLITO RS04425
gene id: 216942:SLITO_RS04425
uniprot id: A0A0K1W2B5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

216942:SLITO RS00025
gene id: 216942:SLITO_RS00025
uniprot id: A0A0K1W0N9
names: Similarity
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.

216942:SLITO RS05085
gene id: 216942:SLITO_RS05085
uniprot id: A0A0K1W2P5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

216942:SLITO RS05315
gene id: 216942:SLITO_RS05315
uniprot id: A0A0K1W380
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

216942:SLITO RS01195
gene id: 216942:SLITO_RS01195
uniprot id: A0A0K1W0N8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

216942:SLITO RS04570
gene id: 216942:SLITO_RS04570
uniprot id: A0A0K1W2E2
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

216942:SLITO RS02270
gene id: 216942:SLITO_RS02270
uniprot id: A0A0K1W172
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

216942:SLITO RS00225
gene id: 216942:SLITO_RS00225
uniprot id: A0A0K1W071
names: Similarity
messages: Belongs to the LacAB/RpiB family.

216942:SLITO RS04095
gene id: 216942:SLITO_RS04095
uniprot id: A0A0K1W2U6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

216942:SLITO RS01575
gene id: 216942:SLITO_RS01575
uniprot id: A0A0K1W191
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Membrane

216942:SLITO RS04555
gene id: 216942:SLITO_RS04555
uniprot id: A0A0K1W327
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

216942:SLITO RS01395
gene id: 216942:SLITO_RS01395
uniprot id: A0A0K1W1E0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

216942:SLITO RS05140
gene id: 216942:SLITO_RS05140
uniprot id: A0A0K1W354
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

216942:SLITO RS01680
gene id: 216942:SLITO_RS01680
uniprot id: A0A0K1W0W0
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

216942:SLITO RS03615
gene id: 216942:SLITO_RS03615
uniprot id: A0A0K1W2L5
names: Function
names: Similarity
messages: Belongs to the RmuC family.
messages: Involved in DNA recombination.

216942:SLITO RS02665
gene id: 216942:SLITO_RS02665
uniprot id: A0A0K1W1F1
names: Subcellular Location Annotation
messages: Membrane

216942:SLITO RS01040
gene id: 216942:SLITO_RS01040
uniprot id: A0A0K1W178
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

216942:SLITO RS01400
gene id: 216942:SLITO_RS01400
uniprot id: A0A0K1W161
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

216942:SLITO RS05580
gene id: 216942:SLITO_RS05580
uniprot id: A0A0K1W3E1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

216942:SLITO RS01655
gene id: 216942:SLITO_RS01655
uniprot id: A0A0K1W0V5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

216942:SLITO RS00585
gene id: 216942:SLITO_RS00585
uniprot id: A0A0K1W0F5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Membrane

216942:SLITO RS01630
gene id: 216942:SLITO_RS01630
uniprot id: A0A0K1W0V0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of glycine to tRNA(Gly).
messages: Cytoplasm
messages: Homodimer.

216942:SLITO RS02035
gene id: 216942:SLITO_RS02035
uniprot id: A0A0K1W1Q5
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

216942:SLITO RS00040
gene id: 216942:SLITO_RS00040
uniprot id: A0A0K1W035
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

216942:SLITO RS05090
gene id: 216942:SLITO_RS05090
uniprot id: A0A0K1W345
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

216942:SLITO RS05060
gene id: 216942:SLITO_RS05060
uniprot id: A0A0K1W2P0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

216942:SLITO RS00995
gene id: 216942:SLITO_RS00995
uniprot id: A0A0K1W0Z5
names: Subcellular Location Annotation
messages: Membrane

216942:SLITO RS00250
gene id: 216942:SLITO_RS00250
uniprot id: A0A0K1W079
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase delta chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

216942:SLITO RS04955
gene id: 216942:SLITO_RS04955
uniprot id: A0A0K1W2L6
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

216942:SLITO RS05035
gene id: 216942:SLITO_RS05035
uniprot id: A0A0K1W2N4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

216942:SLITO RS01770
gene id: 216942:SLITO_RS01770
uniprot id: A0A0K1W1K7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Membrane

216942:SLITO RS00310
gene id: 216942:SLITO_RS00310
uniprot id: A0A0K1W0U2
names: Similarity
messages: Belongs to the HPrK/P family.

216942:SLITO RS04825
gene id: 216942:SLITO_RS04825
uniprot id: A0A0K1W366
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the BPG-independent phosphoglycerate mutase family.
messages: Binds 2 manganese ions per subunit.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: Monomer.

216942:SLITO RS02990
gene id: 216942:SLITO_RS02990
uniprot id: A0A0K1W1Z9
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

216942:SLITO RS01130
gene id: 216942:SLITO_RS01130
uniprot id: A0A0K1W193
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.

216942:SLITO RS00220
gene id: 216942:SLITO_RS00220
uniprot id: A0A0K1W0K2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

216942:SLITO RS04560
gene id: 216942:SLITO_RS04560
uniprot id: A0A0K1W2U5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

216942:SLITO RS03595
gene id: 216942:SLITO_RS03595
uniprot id: A0A0K1W2C6
names: Similarity
messages: Belongs to the LacAB/RpiB family.

216942:SLITO RS03895
gene id: 216942:SLITO_RS03895
uniprot id: A0A0K1W2H2
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

216942:SLITO RS00065
gene id: 216942:SLITO_RS00065
uniprot id: A0A0K1W040
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Cytoplasm
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
messages: The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.

216942:SLITO RS04970
gene id: 216942:SLITO_RS04970
uniprot id: A0A0K1W392
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

216942:SLITO RS05945
gene id: 216942:SLITO_RS05945
uniprot id: A0A0K1W0W9
names: Subcellular Location Annotation
messages: Membrane

216942:SLITO RS01890
gene id: 216942:SLITO_RS01890
uniprot id: A0A0K1W0Z4
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

216942:SLITO RS04340
gene id: 216942:SLITO_RS04340
uniprot id: A0A0K1W299
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PPase family.
messages: Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
messages: Cytoplasm
messages: Homohexamer.

216942:SLITO RS05510
gene id: 216942:SLITO_RS05510
uniprot id: A0A0K1W2Y6
names: Similarity
messages: Belongs to the IspF family.

216942:SLITO RS00485
gene id: 216942:SLITO_RS00485
uniprot id: A0A0K1W0D8
names: Function
names: Similarity
messages: Belongs to the NrdI family.
messages: Probably involved in ribonucleotide reductase function.

216942:SLITO RS01490
gene id: 216942:SLITO_RS01490
uniprot id: A0A0K1W169
names: Function
names: Similarity
messages: Belongs to the dihydrofolate reductase family.
messages: Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.

216942:SLITO RS05455
gene id: 216942:SLITO_RS05455
uniprot id: A0A0K1W3B5
names: Function
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

216942:SLITO RS00470
gene id: 216942:SLITO_RS00470
uniprot id: A0A0K1W0Q7
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

216942:SLITO RS05495
gene id: 216942:SLITO_RS05495
uniprot id: A0A0K1W3B4
names: Similarity
messages: Belongs to the RpoE family.

216942:SLITO RS04680
gene id: 216942:SLITO_RS04680
uniprot id: A0A0K1W344
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm

216942:SLITO RS00265
gene id: 216942:SLITO_RS00265
uniprot id: A0A0K1W0L4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

216942:SLITO RS04450
gene id: 216942:SLITO_RS04450
uniprot id: A0A0K1W2C0
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

216942:SLITO RS00255
gene id: 216942:SLITO_RS00255
uniprot id: A0A0K1W0J5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

216942:SLITO RS05570
gene id: 216942:SLITO_RS05570
uniprot id: A0A0K1W3C9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the N7 position of a guanine in 16S rRNA.

216942:SLITO RS02095
gene id: 216942:SLITO_RS02095
uniprot id: A0A0K1W139
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uridine kinase family.
messages: Cytoplasm

216942:SLITO RS02160
gene id: 216942:SLITO_RS02160
uniprot id: A0A0K1W1S0
names: Similarity
messages: Belongs to the NAPRTase family.

216942:SLITO RS03995
gene id: 216942:SLITO_RS03995
uniprot id: A0A0K1W2J3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

216942:SLITO RS04605
gene id: 216942:SLITO_RS04605
uniprot id: A0A0K1W2E6
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

216942:SLITO RS00555
gene id: 216942:SLITO_RS00555
uniprot id: A0A0K1W0T8
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.

216942:SLITO RS03060
gene id: 216942:SLITO_RS03060
uniprot id: A0A0K1W206
names: Subcellular Location Annotation
messages: Membrane

216942:SLITO RS02375
gene id: 216942:SLITO_RS02375
uniprot id: A0A0K1W192
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Membrane

216942:SLITO RS03505
gene id: 216942:SLITO_RS03505
uniprot id: A0A0K1W2A6
names: Subcellular Location Annotation
messages: Membrane

216942:SLITO RS02935
gene id: 216942:SLITO_RS02935
uniprot id: A0A0K1W1J4
names: Similarity
messages: Belongs to the 6-phosphogluconate dehydrogenase family.

216942:SLITO RS02140
gene id: 216942:SLITO_RS02140
uniprot id: A0A0K1W1K0
names: Cofactor
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. NagA family.
messages: Binds 1 divalent metal cation per subunit.

216942:SLITO RS01095
gene id: 216942:SLITO_RS01095
uniprot id: A0A0K1W188
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

216942:SLITO RS02810
gene id: 216942:SLITO_RS02810
uniprot id: A0A0K1W1W3
names: Similarity
messages: Belongs to the glycosyl hydrolase 32 family.

216942:SLITO RS02175
gene id: 216942:SLITO_RS02175
uniprot id: A0A0K1W151
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

216942:SLITO RS05605
gene id: 216942:SLITO_RS05605
uniprot id: A0A0K1W3E6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

216942:SLITO RS02415
gene id: 216942:SLITO_RS02415
uniprot id: A0A0K1W1P2
names: Similarity
messages: Belongs to the glycosyl hydrolase 18 family.

216942:SLITO RS05125
gene id: 216942:SLITO_RS05125
uniprot id: A0A0K1W356
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

216942:SLITO RS02640
gene id: 216942:SLITO_RS02640
uniprot id: A0A0K1W1E6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0154 family.
messages: Membrane

216942:SLITO RS04710
gene id: 216942:SLITO_RS04710
uniprot id: A0A0K1W2X0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

216942:SLITO RS01235
gene id: 216942:SLITO_RS01235
uniprot id: A0A0K1W116
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

216942:SLITO RS03880
gene id: 216942:SLITO_RS03880
uniprot id: A0A0K1W2H5
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

216942:SLITO RS05015
gene id: 216942:SLITO_RS05015
uniprot id: A0A0K1W329
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

216942:SLITO RS05165
gene id: 216942:SLITO_RS05165
uniprot id: A0A0K1W358
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

216942:SLITO RS00580
gene id: 216942:SLITO_RS00580
uniprot id: A0A0K1W0U4
names: Subcellular Location Annotation
messages: Membrane

216942:SLITO RS05710
gene id: 216942:SLITO_RS05710
uniprot id: A0A0K1W330
names: Similarity
messages: Belongs to the phosphate acetyltransferase and butyryltransferase family.

216942:SLITO RS00570
gene id: 216942:SLITO_RS00570
uniprot id: A0A0K1W0S4
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.