216778:DX03 RS15440
gene id: 216778:DX03_RS15440
uniprot id: A0A023Y648
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

216778:DX03 RS10120
gene id: 216778:DX03_RS10120
uniprot id: A0A023Y449
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Member of the two-component regulatory system NreB/NreC involved in the control of dissimilatory nitrate/nitrite reduction in response to oxygen. NreB functions as a direct oxygen sensor histidine kinase which is autophosphorylated, in the absence of oxygen, probably at the conserved histidine residue, and transfers its phosphate group probably to a conserved aspartate residue of NreC. NreB/NreC activates the expression of the nitrate (narGHJI) and nitrite (nir) reductase operons, as well as the putative nitrate transporter gene narT.

216778:DX03 RS13685
gene id: 216778:DX03_RS13685
uniprot id: A0A023Y610
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RlmJ family.
messages: Monomer.
messages: Specifically methylates the adenine in position 2030 of 23S rRNA.

216778:DX03 RS20110
gene id: 216778:DX03_RS20110
uniprot id: A0A023Y9E9
names: Similarity
messages: Belongs to the nitroreductase family.

216778:DX03 RS13770
gene id: 216778:DX03_RS13770
uniprot id: A0A023Y5P5
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

216778:DX03 RS18890
gene id: 216778:DX03_RS18890
uniprot id: A0A023Y8X3
names: Subcellular Location Annotation
messages: Membrane

216778:DX03 RS02110
gene id: 216778:DX03_RS02110
uniprot id: A0A023XYN2
names: Similarity
messages: Belongs to the GST superfamily.

216778:DX03 RS17955
gene id: 216778:DX03_RS17955
uniprot id: A0A023Y7J5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Membrane

216778:DX03 RS04805
gene id: 216778:DX03_RS04805
uniprot id: A0A023Y120
names: Similarity
messages: Belongs to the prokaryotic GSH synthase family.

216778:DX03 RS08060
gene id: 216778:DX03_RS08060
uniprot id: A0A023Y291
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CitM (TC 2.A.11) transporter family.
messages: Cell membrane
messages: Membrane

216778:DX03 RS15150
gene id: 216778:DX03_RS15150
uniprot id: A0A023Y5Y3
names: Function
names: Similarity
messages: Belongs to the transglycosylase MltG family.
messages: Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.

216778:DX03 RS15840
gene id: 216778:DX03_RS15840
uniprot id: A0A023Y6U4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

216778:DX03 RS08755
gene id: 216778:DX03_RS08755
uniprot id: A0A023Y2W6
names: Similarity
messages: Belongs to the ClpA/ClpB family.

216778:DX03 RS05225
gene id: 216778:DX03_RS05225
uniprot id: A0A023Y0F9
names: Function
names: Similarity
messages: Belongs to the peroxiredoxin family. Prx5 subfamily.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

216778:DX03 RS01580
gene id: 216778:DX03_RS01580
uniprot id: A0A023XYB3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AceK family.
messages: Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation.
messages: Cytoplasm

216778:DX03 RS07785
gene id: 216778:DX03_RS07785
uniprot id: A0A023Y2U1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

216778:DX03 RS18500
gene id: 216778:DX03_RS18500
uniprot id: A0A023Y7R2
names: Similarity
messages: Belongs to the UPF0337 (CsbD) family.

216778:DX03 RS05130
gene id: 216778:DX03_RS05130
uniprot id: A0A023Y0M2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the uroporphyrinogen decarboxylase family.
messages: Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

216778:DX03 RS10820
gene id: 216778:DX03_RS10820
uniprot id: A0A023Y4G1
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

216778:DX03 RS00715
gene id: 216778:DX03_RS00715
uniprot id: A0A023XYU3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

216778:DX03 RS13015
gene id: 216778:DX03_RS13015
uniprot id: A0A023Y5Q7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

216778:DX03 RS15585
gene id: 216778:DX03_RS15585
uniprot id: A0A023Y6R0
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

216778:DX03 RS03030
gene id: 216778:DX03_RS03030
uniprot id: A0A023Y026
names: Function
names: Similarity
messages: Belongs to the HPPK family.
messages: Catalyzes the transfer of pyrophosphate from adenosine triphosphate (ATP) to 6-hydroxymethyl-7,8-dihydropterin, an enzymatic step in folate biosynthesis pathway.

216778:DX03 RS14250
gene id: 216778:DX03_RS14250
uniprot id: A0A023Y673
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MdcC family.
messages: Covalently binds the prosthetic group of malonate decarboxylase.
messages: Cytoplasm
messages: Subunit of malonate decarboxylase, it is an acyl carrier protein to which acetyl and malonyl thioester residues are bound via a 2'-(5''-phosphoribosyl)-3'-dephospho-CoA prosthetic group and turn over during the catalytic mechanism.

216778:DX03 RS06800
gene id: 216778:DX03_RS06800
uniprot id: A0A023Y185
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

216778:DX03 RS12705
gene id: 216778:DX03_RS12705
uniprot id: A0A023Y5L0
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

216778:DX03 RS05835
gene id: 216778:DX03_RS05835
uniprot id: A0A023Y0Q5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

216778:DX03 RS01450
gene id: 216778:DX03_RS01450
uniprot id: A0A023XYU4
names: Function
names: Similarity
messages: Belongs to the bacterioferritin family.
messages: Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex.

216778:DX03 RS17965
gene id: 216778:DX03_RS17965
uniprot id: A0A023Y8I6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Cell membrane
messages: Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.
messages: Membrane

216778:DX03 RS09180
gene id: 216778:DX03_RS09180
uniprot id: A0A023Y3E3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Membrane
messages: The cytochrome bo(3) ubiquinol oxidase complex is a heterooctamer of two A chains, two B chains, two C chains and two D chains.

216778:DX03 RS16335
gene id: 216778:DX03_RS16335
uniprot id: A0A023Y7C4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

216778:DX03 RS03935
gene id: 216778:DX03_RS03935
uniprot id: A0A023Y092
names: Function
names: Similarity
messages: Belongs to the helicase family. RecG subfamily.
messages: Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA).

216778:DX03 RS09710
gene id: 216778:DX03_RS09710
uniprot id: A0A023Y2V6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

216778:DX03 RS14765
gene id: 216778:DX03_RS14765
uniprot id: A0A023Y688
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

216778:DX03 RS06495
gene id: 216778:DX03_RS06495
uniprot id: A0A023Y204
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

216778:DX03 RS00400
gene id: 216778:DX03_RS00400
uniprot id: A0A023XYA0
names: Subcellular Location Annotation
messages: Membrane

216778:DX03 RS00630
gene id: 216778:DX03_RS00630
uniprot id: A0A023XXV1
names: Similarity
messages: Belongs to the GST superfamily.

216778:DX03 RS13255
gene id: 216778:DX03_RS13255
uniprot id: A0A023Y5U2
names: Function
names: Similarity
messages: Belongs to the bacterioferritin family.
messages: Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex.

216778:DX03 RS11580
gene id: 216778:DX03_RS11580
uniprot id: A0A023Y3V6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

216778:DX03 RS05245
gene id: 216778:DX03_RS05245
uniprot id: A0A023Y122
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the band 7/mec-2 family. HflK subfamily.
messages: HflC and HflK could encode or regulate a protease.
messages: HflC and HflK may interact to form a multimeric complex.
messages: Membrane

216778:DX03 RS01970
gene id: 216778:DX03_RS01970
uniprot id: A0A023XZI5
names: Similarity
messages: Belongs to the CutA family.

216778:DX03 RS05940
gene id: 216778:DX03_RS05940
uniprot id: A0A023Y0Z6
names: Similarity
messages: Belongs to the peptidase M13 family.

216778:DX03 RS16500
gene id: 216778:DX03_RS16500
uniprot id: A0A023Y6U2
names: Function
names: Similarity
messages: Belongs to the LpxC family.
messages: Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.

216778:DX03 RS03180
gene id: 216778:DX03_RS03180
uniprot id: A0A023Y082
names: PTM
messages: Binds 2 heme c groups covalently per subunit.

216778:DX03 RS00585
gene id: 216778:DX03_RS00585
uniprot id: A0A023XY04
names: Similarity
messages: Belongs to the peptidase S33 family.

216778:DX03 RS11810
gene id: 216778:DX03_RS11810
uniprot id: A0A023Y499
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

216778:DX03 RS18335
gene id: 216778:DX03_RS18335
uniprot id: A0A023Y8H6
names: Similarity
messages: Belongs to the VgrG protein family.

216778:DX03 RS15535
gene id: 216778:DX03_RS15535
uniprot id: A0A023Y6Q3
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

216778:DX03 RS13490
gene id: 216778:DX03_RS13490
uniprot id: A0A023Y4Z6
names: Similarity
messages: Belongs to the Gfa family.

216778:DX03 RS08420
gene id: 216778:DX03_RS08420
uniprot id: A0A023Y337
names: Subcellular Location Annotation
messages: Membrane

216778:DX03 RS04355
gene id: 216778:DX03_RS04355
uniprot id: A0A023Y0W2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the spermidine/spermine synthase family.
messages: Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
messages: Cell membrane
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Lacks the conserved Asp active site.

216778:DX03 RS19795
gene id: 216778:DX03_RS19795
uniprot id: A0A023Y8Z7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

216778:DX03 RS01540
gene id: 216778:DX03_RS01540
uniprot id: A0A023XZ94
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family. QueF type 2 subfamily.
messages: Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
messages: Cytoplasm
messages: Homodimer.

216778:DX03 RS04930
gene id: 216778:DX03_RS04930
uniprot id: A0A023Y0I8
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

216778:DX03 RS17995
gene id: 216778:DX03_RS17995
uniprot id: A0A023Y8D1
names: Similarity
messages: Belongs to the peptidase S41A family.

216778:DX03 RS14335
gene id: 216778:DX03_RS14335
uniprot id: A0A023Y5E0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

216778:DX03 RS13815
gene id: 216778:DX03_RS13815
uniprot id: A0A023Y5Z2
names: Similarity
messages: Belongs to the glycosyl hydrolase 5 (cellulase A) family.

216778:DX03 RS01630
gene id: 216778:DX03_RS01630
uniprot id: A0A023XYC2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DEAD box helicase family. RhlB subfamily.
messages: Component of the RNA degradosome, which is a multiprotein complex involved in RNA processing and mRNA degradation.
messages: Cytoplasm
messages: DEAD-box RNA helicase involved in RNA degradation. Has RNA-dependent ATPase activity and unwinds double-stranded RNA.

216778:DX03 RS13500
gene id: 216778:DX03_RS13500
uniprot id: A0A023Y5Y5
names: Subcellular Location Annotation
messages: Membrane

216778:DX03 RS06195
gene id: 216778:DX03_RS06195
uniprot id: A0A023Y142
names: Function
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.

216778:DX03 RS10210
gene id: 216778:DX03_RS10210
uniprot id: A0A023Y386
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

216778:DX03 RS08220
gene id: 216778:DX03_RS08220
uniprot id: A0A023Y2B2
names: Function
names: Similarity
messages: Belongs to the DtxR/MntR family.
messages: In the presence of manganese, represses expression of mntH and mntS. Up-regulates expression of mntP.

216778:DX03 RS01400
gene id: 216778:DX03_RS01400
uniprot id: A0A023XYE9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

216778:DX03 RS02245
gene id: 216778:DX03_RS02245
uniprot id: A0A023XZP7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the GTP cyclohydrolase II family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.

216778:DX03 RS11405
gene id: 216778:DX03_RS11405
uniprot id: A0A023Y3R9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCF family. Uup subfamily.
messages: Cytoplasm
messages: Probably plays a role in ribosome assembly or function. May be involved in resolution of branched DNA intermediates that result from template switching in postreplication gaps. Binds DNA and has ATPase activity.

216778:DX03 RS11305
gene id: 216778:DX03_RS11305
uniprot id: A0A023Y3Q3
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

216778:DX03 RS14980
gene id: 216778:DX03_RS14980
uniprot id: A0A023Y6S3
names: Similarity
messages: Belongs to the GSP E family.

216778:DX03 RS07800
gene id: 216778:DX03_RS07800
uniprot id: A0A023Y1X4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

216778:DX03 RS10440
gene id: 216778:DX03_RS10440
uniprot id: A0A023Y3L0
names: Function
messages: Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors. CheA is autophosphorylated; it can transfer its phosphate group to either CheB or CheY.

216778:DX03 RS11610
gene id: 216778:DX03_RS11610
uniprot id: A0A023Y452
names: Similarity
messages: Belongs to the LOG family.

216778:DX03 RS09620
gene id: 216778:DX03_RS09620
uniprot id: A0A023Y3N5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

216778:DX03 RS16350
gene id: 216778:DX03_RS16350
uniprot id: A0A023Y6R8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family.
messages: Membrane

216778:DX03 RS14180
gene id: 216778:DX03_RS14180
uniprot id: A0A023Y5X3
names: Subcellular Location Annotation
messages: Membrane

216778:DX03 RS17935
gene id: 216778:DX03_RS17935
uniprot id: A0A023Y7R9
names: Subcellular Location Annotation
messages: Membrane

216778:DX03 RS06540
gene id: 216778:DX03_RS06540
uniprot id: A0A023Y1B3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the calycin superfamily. Lipocalin family.
messages: Cell outer membrane
messages: Homodimer.
messages: Involved in the storage or transport of lipids necessary for membrane maintenance under stressful conditions. Displays a binding preference for lysophospholipids.

216778:DX03 RS02170
gene id: 216778:DX03_RS02170
uniprot id: A0A023XZN0
names: Subcellular Location Annotation
messages: Membrane

216778:DX03 RS20165
gene id: 216778:DX03_RS20165
uniprot id: A0A023Y980
names: Function
names: Similarity
names: Subunit
messages: A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild-type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity.
messages: Belongs to the RecC family.
messages: Heterotrimer of RecB, RecC and RecD. All subunits contribute to DNA-binding.

216778:DX03 RS12610
gene id: 216778:DX03_RS12610
uniprot id: A0A023Y4K6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

216778:DX03 RS07195
gene id: 216778:DX03_RS07195
uniprot id: A0A023Y1R5
names: Subcellular Location Annotation
messages: Membrane

216778:DX03 RS13655
gene id: 216778:DX03_RS13655
uniprot id: A0A023Y596
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

216778:DX03 RS20210
gene id: 216778:DX03_RS20210
uniprot id: A0A023Y9H0
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family.
messages: Homopolymer.

216778:DX03 RS16120
gene id: 216778:DX03_RS16120
uniprot id: A0A023Y6E8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S33 family.
messages: Cytoplasm

216778:DX03 RS08475
gene id: 216778:DX03_RS08475
uniprot id: A0A023Y311
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

216778:DX03 RS03575
gene id: 216778:DX03_RS03575
uniprot id: A0A023XZN4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

216778:DX03 RS00185
gene id: 216778:DX03_RS00185
uniprot id: A0A023XXU9
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

216778:DX03 RS03345
gene id: 216778:DX03_RS03345
uniprot id: A0A023XZB9
names: Similarity
messages: Belongs to the GST superfamily. NadH family.

216778:DX03 RS03815
gene id: 216778:DX03_RS03815
uniprot id: A0A023XZK1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

216778:DX03 RS11350
gene id: 216778:DX03_RS11350
uniprot id: A0A023Y4E2
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

216778:DX03 RS13340
gene id: 216778:DX03_RS13340
uniprot id: A0A023Y4X2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

216778:DX03 RS00085
gene id: 216778:DX03_RS00085
uniprot id: A0A023XXT2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MntP (TC 9.B.29) family.
messages: Cell membrane
messages: Probably functions as a manganese efflux pump.

216778:DX03 RS01625
gene id: 216778:DX03_RS01625
uniprot id: A0A023XYY3
names: Similarity
messages: Belongs to the thioredoxin family.

216778:DX03 RS17885
gene id: 216778:DX03_RS17885
uniprot id: A0A023Y7R0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

216778:DX03 RS12285
gene id: 216778:DX03_RS12285
uniprot id: A0A023Y4K0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S24 family.
messages: Homodimer.
messages: Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.

216778:DX03 RS15090
gene id: 216778:DX03_RS15090
uniprot id: A0A023Y6G7
names: Similarity
messages: Belongs to the UPF0145 family.

216778:DX03 RS14880
gene id: 216778:DX03_RS14880
uniprot id: A0A023Y6Q0
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HPrK/P family.
messages: Both phosphorylation and phosphorolysis are carried out by the same active site and suggest a common mechanism for both reactions.
messages: Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr).
messages: Homohexamer.
messages: The Walker A ATP-binding motif also binds Pi and PPi.

216778:DX03 RS02540
gene id: 216778:DX03_RS02540
uniprot id: A0A023XYY8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 1 lipoyl cofactor covalently.
messages: Forms a 24-polypeptide structural core with octahedral symmetry.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).

216778:DX03 RS19900
gene id: 216778:DX03_RS19900
uniprot id: A0A023Y8I4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

216778:DX03 RS17035
gene id: 216778:DX03_RS17035
uniprot id: A0A023Y749
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

216778:DX03 RS03535
gene id: 216778:DX03_RS03535
uniprot id: A0A023Y0A8
names: Similarity
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.

216778:DX03 RS19940
gene id: 216778:DX03_RS19940
uniprot id: A0A023Y9C0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PNP synthase family.
messages: Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.
messages: Cytoplasm
messages: Homooctamer; tetramer of dimers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

216778:DX03 RS08270
gene id: 216778:DX03_RS08270
uniprot id: A0A4U3GRR4
names: Caution
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

216778:DX03 RS02460
gene id: 216778:DX03_RS02460
uniprot id: A0A023XZS9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Basic amino acid/polyamine antiporter (APA) (TC 2.A.3.2) family.
messages: Membrane

216778:DX03 RS17485
gene id: 216778:DX03_RS17485
uniprot id: A0A023Y7F3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

216778:DX03 RS10305
gene id: 216778:DX03_RS10305
uniprot id: A0A023Y3V9
names: Function
names: Similarity
messages: Belongs to the FliK family.
messages: Controls the length of the flagellar hook.

216778:DX03 RS00665
gene id: 216778:DX03_RS00665
uniprot id: A0A023XYT7
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Homooctamer.

216778:DX03 RS08415
gene id: 216778:DX03_RS08415
uniprot id: A0A023Y2E0
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-I family.

216778:DX03 RS10545
gene id: 216778:DX03_RS10545
uniprot id: A0A023Y4B7
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

216778:DX03 RS03820
gene id: 216778:DX03_RS03820
uniprot id: A0A023XZS5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).

216778:DX03 RS11055
gene id: 216778:DX03_RS11055
uniprot id: A0A023Y4J7
names: Similarity
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.

216778:DX03 RS09200
gene id: 216778:DX03_RS09200
uniprot id: A0A023Y3I2
names: Similarity
messages: Belongs to the SCO1/2 family.

216778:DX03 RS07505
gene id: 216778:DX03_RS07505
uniprot id: A0A023Y210
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the kynureninase family.
messages: Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3-hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3-hydroxyanthranilic acid (3-OHAA), respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

216778:DX03 RS18410
gene id: 216778:DX03_RS18410
uniprot id: A0A023Y8J0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell inner membrane
messages: Membrane

216778:DX03 RS14480
gene id: 216778:DX03_RS14480
uniprot id: A0A023Y627
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RTX toxin acyltransferase family.
messages: Cytoplasm
messages: Involved in fatty acylation of protoxin at internal lysine residues, thereby converting it to the active toxin.

216778:DX03 RS10000
gene id: 216778:DX03_RS10000
uniprot id: A0A023Y3X0
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fluoride channel Fluc/FEX (TC 1.A.43) family.
messages: Cell membrane
messages: Fluoride-specific ion channel. Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane
messages: Na(+) is not transported, but it plays an essential structural role and its presence is essential for fluoride channel function.

216778:DX03 RS06965
gene id: 216778:DX03_RS06965
uniprot id: A0A023Y2A6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmE/CycJ family.
messages: Cell membrane
messages: Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH.

216778:DX03 RS15855
gene id: 216778:DX03_RS15855
uniprot id: A0A023Y787
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

216778:DX03 RS00935
gene id: 216778:DX03_RS00935
uniprot id: A0A023XXZ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

216778:DX03 RS03310
gene id: 216778:DX03_RS03310
uniprot id: A0A023Y073
names: Similarity
messages: Belongs to the universal stress protein A family.

216778:DX03 RS10220
gene id: 216778:DX03_RS10220
uniprot id: A0A023Y464
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

216778:DX03 RS18995
gene id: 216778:DX03_RS18995
uniprot id: A0A023Y8U2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S-adenosyl-L-methionine to the 2'-OH of the wobble nucleotide.

216778:DX03 RS10195
gene id: 216778:DX03_RS10195
uniprot id: A0A023Y460
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Flagellum-specific muramidase which hydrolyzes the peptidoglycan layer to assemble the rod structure in the periplasmic space.
messages: In the C-terminal section; belongs to the glycosyl hydrolase 73 family.
messages: In the N-terminal section; belongs to the FlgJ family.
messages: Periplasm

216778:DX03 RS05675
gene id: 216778:DX03_RS05675
uniprot id: A0A023Y178
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.

216778:DX03 RS02600
gene id: 216778:DX03_RS02600
uniprot id: A0A023XZY5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

216778:DX03 RS06795
gene id: 216778:DX03_RS06795
uniprot id: A0A023Y1T9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. AOTCase family.
messages: Catalyzes the transfer of the carbamoyl group from carbamoyl phosphate to the delta-amino group of N(2)-acetyl-L-ornithine to produce N(2)-acetyl-L-citrulline. This is a step in an alternative arginine biosynthesis pathway.
messages: Cytoplasm
messages: Homotrimer.

216778:DX03 RS12780
gene id: 216778:DX03_RS12780
uniprot id: A0A023Y5M3
names: Similarity
messages: Belongs to the transglycosylase Slt family.

216778:DX03 RS03910
gene id: 216778:DX03_RS03910
uniprot id: A0A023Y087
names: Similarity
messages: Belongs to the YicC/YloC family.

216778:DX03 RS20050
gene id: 216778:DX03_RS20050
uniprot id: A0A023Y955
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TerC family.
messages: Membrane

216778:DX03 RS05200
gene id: 216778:DX03_RS05200
uniprot id: A0A023Y0F7
names: Similarity
messages: Belongs to the PrpF family.

216778:DX03 RS07820
gene id: 216778:DX03_RS07820
uniprot id: A0A023Y2G4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Also exhibits azoreductase activity. Catalyzes the reductive cleavage of the azo bond in aromatic azo compounds to the corresponding amines.
messages: Belongs to the azoreductase type 1 family.
messages: Binds 1 FMN per subunit.
messages: Homodimer.
messages: Quinone reductase that provides resistance to thiol-specific stress caused by electrophilic quinones.

216778:DX03 RS02205
gene id: 216778:DX03_RS02205
uniprot id: A0A023XZC1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Cytoplasm
messages: Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.

216778:DX03 RS19580
gene id: 216778:DX03_RS19580
uniprot id: A0A023Y8B0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the OMP decarboxylase family. Type 1 subfamily.
messages: Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
messages: Homodimer.

216778:DX03 RS10710
gene id: 216778:DX03_RS10710
uniprot id: A0A023Y3F4
names: Function
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

216778:DX03 RS07300
gene id: 216778:DX03_RS07300
uniprot id: A0A023Y1U0
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins.

216778:DX03 RS03955
gene id: 216778:DX03_RS03955
uniprot id: A0A023Y0I3
names: Similarity
messages: Belongs to the citrate synthase family.

216778:DX03 RS14090
gene id: 216778:DX03_RS14090
uniprot id: A0A023Y681
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Homodimer.
messages: Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate.

216778:DX03 RS11410
gene id: 216778:DX03_RS11410
uniprot id: A0A023Y414
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

216778:DX03 RS11630
gene id: 216778:DX03_RS11630
uniprot id: A0A023Y3W8
names: Similarity
messages: Belongs to the IMPACT family.

216778:DX03 RS02695
gene id: 216778:DX03_RS02695
uniprot id: A0A023XZ84
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the glyoxalase I family.
messages: Binds 1 nickel ion per subunit.
messages: Binds 1 zinc ion per subunit. In the homodimer, two zinc ions are bound between subunits.
messages: Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione.

216778:DX03 RS01515
gene id: 216778:DX03_RS01515
uniprot id: A0A023XZ89
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

216778:DX03 RS16550
gene id: 216778:DX03_RS16550
uniprot id: A0A023Y6V0
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

216778:DX03 RS14005
gene id: 216778:DX03_RS14005
uniprot id: A0A023Y581
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurJ/MviN family.
messages: Cell inner membrane
messages: Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.
messages: Membrane

216778:DX03 RS19300
gene id: 216778:DX03_RS19300
uniprot id: A0A023Y8P5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

216778:DX03 RS06125
gene id: 216778:DX03_RS06125
uniprot id: A0A023Y1Q6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccD/PCCB family.
messages: Binds 1 zinc ion per subunit.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

216778:DX03 RS02575
gene id: 216778:DX03_RS02575
uniprot id: A0A023XZY0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0). The b'-subunit is a diverged and duplicated form of b found in plants and photosynthetic bacteria.
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

216778:DX03 RS15210
gene id: 216778:DX03_RS15210
uniprot id: A0A023Y6A1
names: Subcellular Location Annotation
messages: Membrane

216778:DX03 RS14865
gene id: 216778:DX03_RS14865
uniprot id: A0A4U3GMU9
names: Caution
names: Function
names: Similarity
messages: Belongs to the sigma-54 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

216778:DX03 RS20025
gene id: 216778:DX03_RS20025
uniprot id: A0A023Y949
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
messages: Binds 1 potassium ion per subunit.
messages: Cytoplasm
messages: Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

216778:DX03 RS17005
gene id: 216778:DX03_RS17005
uniprot id: A0A023Y6W0
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit A family.

216778:DX03 RS04910
gene id: 216778:DX03_RS04910
uniprot id: A0A023Y1A1
names: Similarity
messages: Belongs to the GMC oxidoreductase family.

216778:DX03 RS02580
gene id: 216778:DX03_RS02580
uniprot id: A0A023XZU6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase delta chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

216778:DX03 RS11565
gene id: 216778:DX03_RS11565
uniprot id: A0A023Y4U1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TER reductase family.
messages: Involved in the final reduction of the elongation cycle of fatty acid synthesis (FAS II). Catalyzes the reduction of a carbon-carbon double bond in an enoyl moiety that is covalently linked to an acyl carrier protein (ACP).
messages: Monomer.

216778:DX03 RS11990
gene id: 216778:DX03_RS11990
uniprot id: A0A023Y538
names: Cofactor
names: Function
names: Similarity
messages: Adenine glycosylase active on G-A mispairs. MutY also corrects error-prone DNA synthesis past GO lesions which are due to the oxidatively damaged form of guanine: 7,8-dihydro-8-oxoguanine (8-oxo-dGTP).
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.

216778:DX03 RS04190
gene id: 216778:DX03_RS04190
uniprot id: A0A023XZS8
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

216778:DX03 RS06755
gene id: 216778:DX03_RS06755
uniprot id: A0A023Y263
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.

216778:DX03 RS19255
gene id: 216778:DX03_RS19255
uniprot id: A0A023Y844
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Member of the two-component regulatory system NtrB/NtrC, which controls expression of the nitrogen-regulated (ntr) genes in response to nitrogen limitation. Phosphorylated NtrC binds directly to DNA and stimulates the formation of open promoter-sigma54-RNA polymerase complexes.

216778:DX03 RS01975
gene id: 216778:DX03_RS01975
uniprot id: A0A023XZG8
names: Similarity
messages: Belongs to the EndA/NucM nuclease family.

216778:DX03 RS20415
gene id: 216778:DX03_RS20415
uniprot id: A0A023Y2A4
names: Similarity
messages: Belongs to the SOS response-associated peptidase family.

216778:DX03 RS02995
gene id: 216778:DX03_RS02995
uniprot id: A0A023XZD1
names: Similarity
messages: Belongs to the 6-phosphogluconate dehydrogenase family.

216778:DX03 RS14015
gene id: 216778:DX03_RS14015
uniprot id: A0A023Y668
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

216778:DX03 RS14010
gene id: 216778:DX03_RS14010
uniprot id: A0A023Y5G2
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

216778:DX03 RS12010
gene id: 216778:DX03_RS12010
uniprot id: A0A023Y4E6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

216778:DX03 RS05520
gene id: 216778:DX03_RS05520
uniprot id: A0A023Y1F2
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

216778:DX03 RS13110
gene id: 216778:DX03_RS13110
uniprot id: A0A023Y510
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PstS family.
messages: Part of the ABC transporter complex PstSACB involved in phosphate import.
messages: The complex is composed of two ATP-binding proteins (PstB), two transmembrane proteins (PstC and PstA) and a solute-binding protein (PstS).

216778:DX03 RS11680
gene id: 216778:DX03_RS11680
uniprot id: A0A023Y3X6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

216778:DX03 RS05315
gene id: 216778:DX03_RS05315
uniprot id: A0A023Y1G0
names: Similarity
messages: Belongs to the SIP oxidoreductase family.

216778:DX03 RS15610
gene id: 216778:DX03_RS15610
uniprot id: A0A023Y6R4
names: Similarity
messages: In the N-terminal section; belongs to the NADH:flavin oxidoreductase/NADH oxidase family.

216778:DX03 RS05655
gene id: 216778:DX03_RS05655
uniprot id: A0A023Y0M4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LPG synthase family.
messages: Membrane

216778:DX03 RS11705
gene id: 216778:DX03_RS11705
uniprot id: A0A023Y3Y2
names: Similarity
messages: Belongs to the UPF0125 (RnfH) family.

216778:DX03 RS19730
gene id: 216778:DX03_RS19730
uniprot id: A0A023Y8N7
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

216778:DX03 RS14125
gene id: 216778:DX03_RS14125
uniprot id: A0A023Y5W3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0382 family.
messages: Membrane

216778:DX03 RS06045
gene id: 216778:DX03_RS06045
uniprot id: A0A023Y1S3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Reduced FMN (FMNH(2)).

216778:DX03 RS02970
gene id: 216778:DX03_RS02970
uniprot id: A0A023XZC9
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LipB family.
messages: Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
messages: Cytoplasm
messages: In the reaction, the free carboxyl group of octanoic acid is attached via an amide linkage to the epsilon-amino group of a specific lysine residue of lipoyl domains of lipoate-dependent enzymes.

216778:DX03 RS02955
gene id: 216778:DX03_RS02955
uniprot id: A0A023Y013
names: Function
names: Similarity
messages: Belongs to the peptidase S11 family.
messages: Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors.

216778:DX03 RS16230
gene id: 216778:DX03_RS16230
uniprot id: A0A023Y7E5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

216778:DX03 RS02620
gene id: 216778:DX03_RS02620
uniprot id: A0A023XZ71
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
messages: Cytoplasm
messages: Homotrimer.
messages: In the C-terminal section; belongs to the transferase hexapeptide repeat family.
messages: In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.

216778:DX03 RS00275
gene id: 216778:DX03_RS00275
uniprot id: A0A023XY85
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

216778:DX03 RS02215
gene id: 216778:DX03_RS02215
uniprot id: A0A023XYY0
names: Subcellular Location Annotation
messages: Membrane

216778:DX03 RS11655
gene id: 216778:DX03_RS11655
uniprot id: A0A023Y3X2
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

216778:DX03 RS04885
gene id: 216778:DX03_RS04885
uniprot id: A0A023Y193
names: Subcellular Location Annotation
messages: Membrane

216778:DX03 RS05795
gene id: 216778:DX03_RS05795
uniprot id: A0A023Y1N4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YhdE subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

216778:DX03 RS06100
gene id: 216778:DX03_RS06100
uniprot id: A0A023Y1Q2
names: Similarity
messages: Belongs to the TelA family.

216778:DX03 RS16170
gene id: 216778:DX03_RS16170
uniprot id: A0A023Y6F8
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

216778:DX03 RS13395
gene id: 216778:DX03_RS13395
uniprot id: A0A023Y554
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioester dehydratase family. FabZ subfamily.
messages: Cytoplasm
messages: Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.

216778:DX03 RS01600
gene id: 216778:DX03_RS01600
uniprot id: A0A023XYX6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

216778:DX03 RS11185
gene id: 216778:DX03_RS11185
uniprot id: A0A023Y3X5
names: Similarity
messages: To bacterial alkanal monooxygenase alpha and beta chains.

216778:DX03 RS17200
gene id: 216778:DX03_RS17200
uniprot id: A0A023Y7K0
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

216778:DX03 RS00660
gene id: 216778:DX03_RS00660
uniprot id: A0A023XY19
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anion channel-forming bestrophin (TC 1.A.46) family.
messages: Membrane

216778:DX03 RS10380
gene id: 216778:DX03_RS10380
uniprot id: A0A023Y3W9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTP-binding SRP family.
messages: Cell membrane
messages: Membrane
messages: Necessary for flagellar biosynthesis. May be involved in translocation of the flagellum.

216778:DX03 RS13620
gene id: 216778:DX03_RS13620
uniprot id: A0A023Y518
names: Subcellular Location Annotation
messages: Membrane

216778:DX03 RS06820
gene id: 216778:DX03_RS06820
uniprot id: A0A023Y1U4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

216778:DX03 RS19250
gene id: 216778:DX03_RS19250
uniprot id: A0A023Y8N6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Cu-Zn superoxide dismutase family.
messages: Binds 1 copper ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

216778:DX03 RS01985
gene id: 216778:DX03_RS01985
uniprot id: A0A023XYK1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

216778:DX03 RS09970
gene id: 216778:DX03_RS09970
uniprot id: A0A023Y3Z7
names: Similarity
messages: Belongs to the GST superfamily.

216778:DX03 RS14160
gene id: 216778:DX03_RS14160
uniprot id: A0A023Y5A8
names: Function
names: Similarity
messages: Belongs to the MinE family.
messages: Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.

216778:DX03 RS03800
gene id: 216778:DX03_RS03800
uniprot id: A0A023Y0I9
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: May also have succinyldiaminopimelate aminotransferase activity, thus carrying out the corresponding step in lysine biosynthesis.

216778:DX03 RS10445
gene id: 216778:DX03_RS10445
uniprot id: A0A023Y4A1
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

216778:DX03 RS19620
gene id: 216778:DX03_RS19620
uniprot id: A0A023Y952
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

216778:DX03 RS10340
gene id: 216778:DX03_RS10340
uniprot id: A0A023Y3J4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliR/MopE/SpaR family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

216778:DX03 RS06070
gene id: 216778:DX03_RS06070
uniprot id: A0A023Y1S6
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

216778:DX03 RS10370
gene id: 216778:DX03_RS10370
uniprot id: A0A023Y489
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type III secretion exporter family.
messages: Cell membrane
messages: Membrane
messages: Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

216778:DX03 RS11715
gene id: 216778:DX03_RS11715
uniprot id: A0A023Y4X8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

216778:DX03 RS20105
gene id: 216778:DX03_RS20105
uniprot id: A0A023Y9M0
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily.

216778:DX03 RS10185
gene id: 216778:DX03_RS10185
uniprot id: A0A023Y382
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
messages: Bacterial flagellum basal body
messages: Belongs to the FlgH family.
messages: Cell outer membrane
messages: Membrane
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod.

216778:DX03 RS18985
gene id: 216778:DX03_RS18985
uniprot id: A0A023Y877
names: Similarity
messages: Belongs to the peptidase M16 family.

216778:DX03 RS16075
gene id: 216778:DX03_RS16075
uniprot id: A0A023Y6L7
names: Similarity
messages: Belongs to the AlaDH/PNT family.

216778:DX03 RS17760
gene id: 216778:DX03_RS17760
uniprot id: A0A023Y7L6
names: Similarity
messages: Belongs to the acetyl-CoA hydrolase/transferase family.

216778:DX03 RS15795
gene id: 216778:DX03_RS15795
uniprot id: A0A023Y696
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

216778:DX03 RS11015
gene id: 216778:DX03_RS11015
uniprot id: A0A023Y474
names: Function
names: Similarity
names: Subunit
messages: Belongs to the KdsC family.
messages: Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate.
messages: Homotetramer.

216778:DX03 RS16645
gene id: 216778:DX03_RS16645
uniprot id: A0A023Y6P1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.
messages: Forms an icosahedral capsid composed of 60 subunits, arranged as a dodecamer of pentamers.

216778:DX03 RS15475
gene id: 216778:DX03_RS15475
uniprot id: A0A023Y728
names: Function
messages: This protein is a positive regulator for the phosphate regulon. Transcription of this operon is positively regulated by PhoB and PhoR when phosphate is limited.

216778:DX03 RS11930
gene id: 216778:DX03_RS11930
uniprot id: A0A023Y429
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

216778:DX03 RS00075
gene id: 216778:DX03_RS00075
uniprot id: A0A023XY52
names: Function
names: Similarity
messages: Belongs to the peptidase S46 family.
messages: Catalyzes the removal of dipeptides from the N-terminus of oligopeptides.

216778:DX03 RS19690
gene id: 216778:DX03_RS19690
uniprot id: A0A023Y968
names: Similarity
messages: Belongs to the VgrG protein family.

216778:DX03 RS00625
gene id: 216778:DX03_RS00625
uniprot id: A0A023XYD5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0114 family.
messages: Cell membrane
messages: Membrane

216778:DX03 RS11270
gene id: 216778:DX03_RS11270
uniprot id: A0A023Y4J8
names: Similarity
messages: Belongs to the YfgM family.

216778:DX03 RS18435
gene id: 216778:DX03_RS18435
uniprot id: A0A023Y8J4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

216778:DX03 RS09170
gene id: 216778:DX03_RS09170
uniprot id: A0A023Y2T8
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

216778:DX03 RS16760
gene id: 216778:DX03_RS16760
uniprot id: A0A023Y7K2
names: Subcellular Location Annotation
messages: Periplasm

216778:DX03 RS05855
gene id: 216778:DX03_RS05855
uniprot id: A0A023Y1A8
names: Subcellular Location Annotation
messages: Membrane

216778:DX03 RS03360
gene id: 216778:DX03_RS03360
uniprot id: A0A023Y081
names: Similarity
messages: Belongs to the peptidase S8 family.

216778:DX03 RS11265
gene id: 216778:DX03_RS11265
uniprot id: A0A023Y4N2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamB family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

216778:DX03 RS13935
gene id: 216778:DX03_RS13935
uniprot id: A0A023Y653
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

216778:DX03 RS11180
gene id: 216778:DX03_RS11180
uniprot id: A0A023Y3N3
names: Similarity
messages: Belongs to the NtaA/SnaA/DszA monooxygenase family.

216778:DX03 RS13925
gene id: 216778:DX03_RS13925
uniprot id: A0A023Y568
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 2 family.
messages: Membrane

216778:DX03 RS16630
gene id: 216778:DX03_RS16630
uniprot id: A0A023Y7M0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the periplasmic pilus chaperone family.
messages: Periplasm

216778:DX03 RS00070
gene id: 216778:DX03_RS00070
uniprot id: A0A023XYF6
names: Subcellular Location Annotation
messages: Membrane

216778:DX03 RS00220
gene id: 216778:DX03_RS00220
uniprot id: A0A023XYI3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

216778:DX03 RS12605
gene id: 216778:DX03_RS12605
uniprot id: A0A023Y559
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

216778:DX03 RS10055
gene id: 216778:DX03_RS10055
uniprot id: A0A023Y3S0
names: Similarity
messages: Belongs to the ClpA/ClpB family.

216778:DX03 RS15745
gene id: 216778:DX03_RS15745
uniprot id: A0A023Y689
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

216778:DX03 RS01195
gene id: 216778:DX03_RS01195
uniprot id: A0A023XYB2
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

216778:DX03 RS09720
gene id: 216778:DX03_RS09720
uniprot id: A0A023Y3U4
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Catalyzes the phosphorylation of D-xylulose to D-xylulose 5-phosphate.

216778:DX03 RS17540
gene id: 216778:DX03_RS17540
uniprot id: A0A023Y872
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

216778:DX03 RS04960
gene id: 216778:DX03_RS04960
uniprot id: A0A023Y1A9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 51 family.
messages: Cell inner membrane
messages: Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors.

216778:DX03 RS03570
gene id: 216778:DX03_RS03570
uniprot id: A0A023XZF6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 1 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

216778:DX03 RS05840
gene id: 216778:DX03_RS05840
uniprot id: A0A023Y0X8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Cytoplasm
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
messages: The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.

216778:DX03 RS07455
gene id: 216778:DX03_RS07455
uniprot id: A0A023Y1Z1
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

216778:DX03 RS03050
gene id: 216778:DX03_RS03050
uniprot id: A0A023Y060
names: Similarity
messages: Belongs to the glycosyl hydrolase 20 family.

216778:DX03 RS09695
gene id: 216778:DX03_RS09695
uniprot id: A0A023Y3T9
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 67 family.
messages: Homodimer.

216778:DX03 RS16695
gene id: 216778:DX03_RS16695
uniprot id: A0A023Y6Q1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.

216778:DX03 RS02260
gene id: 216778:DX03_RS02260
uniprot id: A0A023XYS3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoD/SigA subfamily.
messages: Cytoplasm
messages: Interacts transiently with the RNA polymerase catalytic core.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.

216778:DX03 RS19195
gene id: 216778:DX03_RS19195
uniprot id: A0A023Y8X4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

216778:DX03 RS15690
gene id: 216778:DX03_RS15690
uniprot id: A0A023Y6S4
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

216778:DX03 RS18865
gene id: 216778:DX03_RS18865
uniprot id: A0A023Y8X0
names: Cofactor
messages: Can also use Mn(2+) ion.

216778:DX03 RS03840
gene id: 216778:DX03_RS03840
uniprot id: A0A023XZK8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ribose 5-phosphate isomerase family.
messages: Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
messages: Homodimer.

216778:DX03 RS16050
gene id: 216778:DX03_RS16050
uniprot id: A0A023Y6L2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PNT beta subunit family.
messages: Cell inner membrane
messages: Heterodimer of an alpha and a beta chain.
messages: Membrane
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

216778:DX03 RS15975
gene id: 216778:DX03_RS15975
uniprot id: A0A023Y6K2
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

216778:DX03 RS06340
gene id: 216778:DX03_RS06340
uniprot id: A0A023Y1U1
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

216778:DX03 RS04595
gene id: 216778:DX03_RS04595
uniprot id: A0A023Y114
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvA family.
messages: Cytoplasm
messages: Has three domains with a flexible linker between the domains II and III and assumes an 'L' shape. Domain III is highly mobile and contacts RuvB.
messages: Homotetramer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

216778:DX03 RS13380
gene id: 216778:DX03_RS13380
uniprot id: A0A023Y5R7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

216778:DX03 RS07610
gene id: 216778:DX03_RS07610
uniprot id: A0A023Y224
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

216778:DX03 RS06180
gene id: 216778:DX03_RS06180
uniprot id: A0A023Y1R4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 30 kDa subunit family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

216778:DX03 RS02195
gene id: 216778:DX03_RS02195
uniprot id: A0A023XZN7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

216778:DX03 RS19870
gene id: 216778:DX03_RS19870
uniprot id: A0A023Y917
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FBPase class 1 family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

216778:DX03 RS10235
gene id: 216778:DX03_RS10235
uniprot id: A0A023Y391
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliS family.
messages: cytosol

216778:DX03 RS20135
gene id: 216778:DX03_RS20135
uniprot id: A0A023Y9F3
names: Similarity
messages: Belongs to the MlaA family.

216778:DX03 RS12765
gene id: 216778:DX03_RS12765
uniprot id: A0A023Y590
names: Cofactor
messages: Binds 1 heme c group covalently per subunit.

216778:DX03 RS15295
gene id: 216778:DX03_RS15295
uniprot id: A0A023Y707
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. KdkA/RfaP family.
messages: Catalyzes the ATP-dependent phosphorylation of the 3-deoxy-D-manno-octulosonic acid (Kdo) residue in Kdo-lipid IV(A) at the 4-OH position.
messages: Cell inner membrane
messages: Membrane

216778:DX03 RS16940
gene id: 216778:DX03_RS16940
uniprot id: A0A023Y7T1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

216778:DX03 RS07290
gene id: 216778:DX03_RS07290
uniprot id: A0A023Y247
names: Similarity
messages: Belongs to the asparagine synthetase family.

216778:DX03 RS15830
gene id: 216778:DX03_RS15830
uniprot id: A0A023Y783
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

216778:DX03 RS17000
gene id: 216778:DX03_RS17000
uniprot id: A0A023Y7F8
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit B family.

216778:DX03 RS18130
gene id: 216778:DX03_RS18130
uniprot id: A0A023Y8K6
names: Similarity
messages: Belongs to the phosphohexose mutase family.

216778:DX03 RS06235
gene id: 216778:DX03_RS06235
uniprot id: A0A023Y1I5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 2 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

216778:DX03 RS14205
gene id: 216778:DX03_RS14205
uniprot id: A0A023Y5X8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

216778:DX03 RS13875
gene id: 216778:DX03_RS13875
uniprot id: A0A023Y560
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. SRP is a ribonucleoprotein composed of Ffh and a 4.5S RNA molecule.

216778:DX03 RS10810
gene id: 216778:DX03_RS10810
uniprot id: A0A023Y3H1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

216778:DX03 RS10145
gene id: 216778:DX03_RS10145
uniprot id: A0A023Y453
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FlgA family.
messages: Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly.
messages: Periplasm

216778:DX03 RS04265
gene id: 216778:DX03_RS04265
uniprot id: A0A023XZU1
names: Subcellular Location Annotation
messages: Membrane

216778:DX03 RS02830
gene id: 216778:DX03_RS02830
uniprot id: A0A023XZZ1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
messages: Belongs to the ClpX chaperone family. HslU subfamily.
messages: Cytoplasm

216778:DX03 RS15205
gene id: 216778:DX03_RS15205
uniprot id: A0A023Y619
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YceF subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes 7-methyl-GTP (m(7)GTP). May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

216778:DX03 RS18600
gene id: 216778:DX03_RS18600
uniprot id: A0A023Y8B7
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

216778:DX03 RS03430
gene id: 216778:DX03_RS03430
uniprot id: A0A023Y0C1
names: Subcellular Location Annotation
messages: Membrane

216778:DX03 RS16525
gene id: 216778:DX03_RS16525
uniprot id: A0A023Y6U7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

216778:DX03 RS16830
gene id: 216778:DX03_RS16830
uniprot id: A0A023Y703
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP I family.
messages: Cell inner membrane
messages: Membrane

216778:DX03 RS10320
gene id: 216778:DX03_RS10320
uniprot id: A0A023Y479
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliN/MopA/SpaO family.
messages: Cell membrane
messages: FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
messages: Membrane

216778:DX03 RS03950
gene id: 216778:DX03_RS03950
uniprot id: A0A023Y0M3
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type B subfamily.
messages: Part of the 50S ribosomal subunit.

216778:DX03 RS10170
gene id: 216778:DX03_RS10170
uniprot id: A0A023Y457
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.

216778:DX03 RS10875
gene id: 216778:DX03_RS10875
uniprot id: A0A023Y4D1
names: Similarity
names: Subunit
messages: Homotetramer.
messages: In the C-terminal section; belongs to the homoserine dehydrogenase family.
messages: In the N-terminal section; belongs to the aspartokinase family.

216778:DX03 RS18145
gene id: 216778:DX03_RS18145
uniprot id: A0A023Y7L4
names: Function
names: Subunit
messages: Adenylyltransferase that mediates the addition of adenosine 5'-monophosphate (AMP) to specific residues of target proteins.
messages: Homodimer.

216778:DX03 RS17440
gene id: 216778:DX03_RS17440
uniprot id: A0A023Y847
names: Similarity
messages: Belongs to the YciI family.

216778:DX03 RS12635
gene id: 216778:DX03_RS12635
uniprot id: A0A023Y4L9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

216778:DX03 RS16705
gene id: 216778:DX03_RS16705
uniprot id: A0A023Y7N3
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.
messages: Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).
messages: The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.
messages: The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1.

216778:DX03 RS03055
gene id: 216778:DX03_RS03055
uniprot id: A0A023Y031
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

216778:DX03 RS19820
gene id: 216778:DX03_RS19820
uniprot id: A0A023Y905
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

216778:DX03 RS04270
gene id: 216778:DX03_RS04270
uniprot id: A0A023Y028
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.

216778:DX03 RS09205
gene id: 216778:DX03_RS09205
uniprot id: A0A023Y3E7
names: Subcellular Location Annotation
messages: Membrane

216778:DX03 RS09025
gene id: 216778:DX03_RS09025
uniprot id: A0A023Y3B2
names: Subcellular Location Annotation
messages: Membrane

216778:DX03 RS18090
gene id: 216778:DX03_RS18090
uniprot id: A0A023Y848
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.

216778:DX03 RS18940
gene id: 216778:DX03_RS18940
uniprot id: A0A023Y8Y1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiJ family.
messages: Cytoplasm
messages: Required for ubiquinone (coenzyme Q) biosynthesis. Binds hydrophobic ubiquinone biosynthetic intermediates via its SCP2 domain and is essential for the stability of the Ubi complex. May constitute a docking platform where Ubi enzymes assemble and access their SCP2-bound polyprenyl substrates.

216778:DX03 RS19490
gene id: 216778:DX03_RS19490
uniprot id: A0A023Y991
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

216778:DX03 RS17465
gene id: 216778:DX03_RS17465
uniprot id: A0A023Y853
names: Subcellular Location Annotation
messages: Membrane

216778:DX03 RS00985
gene id: 216778:DX03_RS00985
uniprot id: A0A023XYK4
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

216778:DX03 RS11815
gene id: 216778:DX03_RS11815
uniprot id: A0A023Y4Z9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Membrane

216778:DX03 RS13405
gene id: 216778:DX03_RS13405
uniprot id: A0A023Y5S3
names: Function
names: Similarity
messages: Belongs to the LpxB family.
messages: Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

216778:DX03 RS16345
gene id: 216778:DX03_RS16345
uniprot id: A0A023Y6I6
names: Similarity
messages: Belongs to the shaker potassium channel beta subunit family.

216778:DX03 RS01410
gene id: 216778:DX03_RS01410
uniprot id: A0A023XZ50
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic AdoMetDC family. Type 2 subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine.
messages: Heterooctamer of four alpha and four beta chains arranged as a tetramer of alpha/beta heterodimers.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl group blocking the N-terminus of the alpha chain.

216778:DX03 RS20045
gene id: 216778:DX03_RS20045
uniprot id: A0A023Y9D9
names: Subcellular Location Annotation
messages: Membrane

216778:DX03 RS16085
gene id: 216778:DX03_RS16085
uniprot id: A0A023Y780
names: Cofactor
names: Similarity
messages: Belongs to the nitroreductase family.
messages: Binds 1 FMN per subunit.

216778:DX03 RS06465
gene id: 216778:DX03_RS06465
uniprot id: A0A023Y1Z9
names: Similarity
messages: Belongs to the peptidase C59 family.

216778:DX03 RS11480
gene id: 216778:DX03_RS11480
uniprot id: A0A023Y3T5
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit A family.

216778:DX03 RS16540
gene id: 216778:DX03_RS16540
uniprot id: A0A023Y769
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane
messages: Membrane

216778:DX03 RS13195
gene id: 216778:DX03_RS13195
uniprot id: A0A023Y5N7
names: Similarity
messages: Belongs to the Gfa family.

216778:DX03 RS19845
gene id: 216778:DX03_RS19845
uniprot id: A0A023Y911
names: Function
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic Ku family.
messages: Homodimer. Interacts with LigD.
messages: With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD.

216778:DX03 RS05180
gene id: 216778:DX03_RS05180
uniprot id: A0A023Y0N0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the isocitrate lyase/PEP mutase superfamily. Methylisocitrate lyase family.
messages: Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate.
messages: Homotetramer; dimer of dimers.
messages: Involved in the catabolism of short chain fatty acids (SCFA) via the 2-methylcitrate cycle (propionate degradation route). Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate via an alpha-carboxy-carbanion intermediate.

216778:DX03 RS17360
gene id: 216778:DX03_RS17360
uniprot id: A0A023Y7C6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

216778:DX03 RS03845
gene id: 216778:DX03_RS03845
uniprot id: A0A023XZT1
names: Subcellular Location Annotation
messages: Nucleus

216778:DX03 RS12125
gene id: 216778:DX03_RS12125
uniprot id: A0A023Y4U5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

216778:DX03 RS15275
gene id: 216778:DX03_RS15275
uniprot id: A0A023Y6W1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

216778:DX03 RS10675
gene id: 216778:DX03_RS10675
uniprot id: A0A023Y498
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

216778:DX03 RS00415
gene id: 216778:DX03_RS00415
uniprot id: A0A023XYP6
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

216778:DX03 RS06415
gene id: 216778:DX03_RS06415
uniprot id: A0A023Y1Y9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

216778:DX03 RS01680
gene id: 216778:DX03_RS01680
uniprot id: A0A023XYD2
names: Similarity
messages: Belongs to the GARS family.

216778:DX03 RS07425
gene id: 216778:DX03_RS07425
uniprot id: A0A023Y1P2
names: Domain
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 dependent methionine synthase family.
messages: Catalyzes the transfer of a methyl group from methyl-cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
messages: Modular enzyme with four functionally distinct domains. The isolated Hcy-binding domain catalyzes methyl transfer from free methylcobalamin to homocysteine. The Hcy-binding domain in association with the pterin-binding domain catalyzes the methylation of cob(I)alamin by methyltetrahydrofolate and the methylation of homocysteine. The B12-binding domain binds the cofactor. The AdoMet activation domain binds S-adenosyl-L-methionine. Under aerobic conditions cob(I)alamin can be converted to inactive cob(II)alamin. Reductive methylation by S-adenosyl-L-methionine and flavodoxin regenerates methylcobalamin.

216778:DX03 RS00655
gene id: 216778:DX03_RS00655
uniprot id: A0A4V5UDY7
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

216778:DX03 RS02825
gene id: 216778:DX03_RS02825
uniprot id: A0A023Y021
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: Allosterically activated by HslU binding.
messages: Belongs to the peptidase T1B family. HslV subfamily.
messages: Cytoplasm
messages: Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.

216778:DX03 RS17235
gene id: 216778:DX03_RS17235
uniprot id: A0A023Y796
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

216778:DX03 RS04360
gene id: 216778:DX03_RS04360
uniprot id: A0A023Y0S2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP E family.
messages: Cytoplasm

216778:DX03 RS06595
gene id: 216778:DX03_RS06595
uniprot id: A0A023Y1C5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

216778:DX03 RS14995
gene id: 216778:DX03_RS14995
uniprot id: A0A023Y5U5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

216778:DX03 RS00105
gene id: 216778:DX03_RS00105
uniprot id: A0A023XXL5
names: Subcellular Location Annotation
messages: Membrane

216778:DX03 RS18440
gene id: 216778:DX03_RS18440
uniprot id: A0A023Y896
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

216778:DX03 RS12120
gene id: 216778:DX03_RS12120
uniprot id: A0A023Y525
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

216778:DX03 RS10855
gene id: 216778:DX03_RS10855
uniprot id: A0A023Y442
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

216778:DX03 RS07555
gene id: 216778:DX03_RS07555
uniprot id: A0A023Y217
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

216778:DX03 RS08160
gene id: 216778:DX03_RS08160
uniprot id: A0A4V6X969
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

216778:DX03 RS13990
gene id: 216778:DX03_RS13990
uniprot id: A0A023Y664
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

216778:DX03 RS14840
gene id: 216778:DX03_RS14840
uniprot id: A0A023Y6A5
names: Similarity
messages: Belongs to the SIS family. GutQ/KpsF subfamily.

216778:DX03 RS11880
gene id: 216778:DX03_RS11880
uniprot id: A0A023Y416
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

216778:DX03 RS07075
gene id: 216778:DX03_RS07075
uniprot id: A0A023Y1Z6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase E/G family. RNase E subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per homotetramer.
messages: Cell inner membrane
messages: Component of the RNA degradosome, which is a multiprotein complex involved in RNA processing and mRNA degradation. Within the RNA degradosome, RNase E assembles into a homotetramer formed by a dimer of dimers.
messages: Cytoplasm
messages: Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs.

216778:DX03 RS00560
gene id: 216778:DX03_RS00560
uniprot id: A0A023XY02
names: Function
names: Similarity
messages: Belongs to the ketopantoate reductase family.
messages: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.

216778:DX03 RS01340
gene id: 216778:DX03_RS01340
uniprot id: A0A023XY74
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

216778:DX03 RS12300
gene id: 216778:DX03_RS12300
uniprot id: A0A023Y4Y1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

216778:DX03 RS10180
gene id: 216778:DX03_RS10180
uniprot id: A0A023Y3U1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

216778:DX03 RS19005
gene id: 216778:DX03_RS19005
uniprot id: A0A023Y7Z8
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

216778:DX03 RS10785
gene id: 216778:DX03_RS10785
uniprot id: A0A023Y3G7
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CutC family.
messages: Cytoplasm
messages: Once thought to be involved in copper homeostasis, experiments in E.coli have shown this is not the case.

216778:DX03 RS05900
gene id: 216778:DX03_RS05900
uniprot id: A0A023Y1L8
names: Similarity
messages: Belongs to the peptidase C40 family.

216778:DX03 RS13070
gene id: 216778:DX03_RS13070
uniprot id: A0A023Y5L5
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

216778:DX03 RS09385
gene id: 216778:DX03_RS09385
uniprot id: A0A023Y3I5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.
messages: Binds 2 iron ions per subunit.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

216778:DX03 RS14055
gene id: 216778:DX03_RS14055
uniprot id: A0A023Y589
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

216778:DX03 RS04160
gene id: 216778:DX03_RS04160
uniprot id: A0A023Y0D7
names: Similarity
messages: Belongs to the pyruvate kinase family.

216778:DX03 RS07865
gene id: 216778:DX03_RS07865
uniprot id: A0A023Y2V5
names: Subcellular Location Annotation
messages: Membrane

216778:DX03 RS12170
gene id: 216778:DX03_RS12170
uniprot id: A0A023Y573
names: Subcellular Location Annotation
messages: Cytoplasm

216778:DX03 RS01330
gene id: 216778:DX03_RS01330
uniprot id: A0A023XZ32
names: Similarity
messages: Belongs to the SAICAR synthetase family.

216778:DX03 RS13175
gene id: 216778:DX03_RS13175
uniprot id: A0A023Y5E6
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

216778:DX03 RS02315
gene id: 216778:DX03_RS02315
uniprot id: A0A023XYU8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anion channel-forming bestrophin (TC 1.A.46) family.
messages: Membrane

216778:DX03 RS12895
gene id: 216778:DX03_RS12895
uniprot id: A0A023Y4Q5
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

216778:DX03 RS01885
gene id: 216778:DX03_RS01885
uniprot id: A0A023XYQ8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

216778:DX03 RS08250
gene id: 216778:DX03_RS08250
uniprot id: A0A023Y317
names: Function
names: Similarity
messages: Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PSRP subfamily.
messages: Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation/dephosphorylation.

216778:DX03 RS06350
gene id: 216778:DX03_RS06350
uniprot id: A0A023Y0Z4
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

216778:DX03 RS19965
gene id: 216778:DX03_RS19965
uniprot id: A0A023Y9J3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

216778:DX03 RS17225
gene id: 216778:DX03_RS17225
uniprot id: A0A023Y7K6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

216778:DX03 RS19950
gene id: 216778:DX03_RS19950
uniprot id: A0A023Y932
names: Subcellular Location Annotation
messages: Membrane

216778:DX03 RS19745
gene id: 216778:DX03_RS19745
uniprot id: A0A023Y8Y7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

216778:DX03 RS15715
gene id: 216778:DX03_RS15715
uniprot id: A0A023Y6S7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

216778:DX03 RS16890
gene id: 216778:DX03_RS16890
uniprot id: A0A023Y7S0
names: Subcellular Location Annotation
messages: Membrane

216778:DX03 RS07515
gene id: 216778:DX03_RS07515
uniprot id: A0A023Y2L1
names: Function
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

216778:DX03 RS13375
gene id: 216778:DX03_RS13375
uniprot id: A0A023Y5W2
names: Caution
names: Function
names: Similarity
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

216778:DX03 RS04590
gene id: 216778:DX03_RS04590
uniprot id: A0A023Y094
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvC family.
messages: Binds 2 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer which binds Holliday junction (HJ) DNA. The HJ becomes 2-fold symmetrical on binding to RuvC with unstacked arms; it has a different conformation from HJ DNA in complex with RuvA. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair. Endonuclease that resolves HJ intermediates. Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction. The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'. Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange. HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

216778:DX03 RS03530
gene id: 216778:DX03_RS03530
uniprot id: A0A023Y0E1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell outer membrane
messages: CyaE is necessary for transport of calmodulin-sensitive adenylate cyclase-hemolysin (cyclolysin).

216778:DX03 RS11050
gene id: 216778:DX03_RS11050
uniprot id: A0A023Y3V2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the etk/wzc family.
messages: Cell inner membrane
messages: Membrane

216778:DX03 RS08410
gene id: 216778:DX03_RS08410
uniprot id: A0A023Y257
names: Subcellular Location Annotation
messages: Membrane

216778:DX03 RS14850
gene id: 216778:DX03_RS14850
uniprot id: A0A023Y5Z7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptC family.
messages: Cell inner membrane
messages: Component of the lipopolysaccharide transport and assembly complex. Interacts with LptA and the LptBFG transporter complex.
messages: Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. Facilitates the transfer of LPS from the inner membrane to the periplasmic protein LptA. Could be a docking site for LptA.

216778:DX03 RS11995
gene id: 216778:DX03_RS11995
uniprot id: A0A023Y4Z7
names: Function
names: Similarity
messages: Belongs to the Fe(2+)-trafficking protein family.
messages: Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes.

216778:DX03 RS08230
gene id: 216778:DX03_RS08230
uniprot id: A0A023Y2X1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-to-5' exoribonuclease specific for small oligoribonucleotides.
messages: Belongs to the oligoribonuclease family.
messages: Cytoplasm

216778:DX03 RS04785
gene id: 216778:DX03_RS04785
uniprot id: A0A4U3GDE1
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

216778:DX03 RS10450
gene id: 216778:DX03_RS10450
uniprot id: A0A023Y461
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)-dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility.
messages: Bacterial flagellum basal body
messages: Belongs to the YcgR family.
messages: Monomer. Interacts with the flagellar basal bodies.

216778:DX03 RS18385
gene id: 216778:DX03_RS18385
uniprot id: A0A023Y8I5
names: Function
names: Similarity
messages: Belongs to the catalase family.
messages: Has an organic peroxide-dependent peroxidase activity.

216778:DX03 RS12660
gene id: 216778:DX03_RS12660
uniprot id: A0A023Y575
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP H family.
messages: Cell inner membrane
messages: Membrane

216778:DX03 RS16520
gene id: 216778:DX03_RS16520
uniprot id: A0A023Y6L5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

216778:DX03 RS18715
gene id: 216778:DX03_RS18715
uniprot id: A0A023Y8U7
names: Function
names: Similarity
messages: Belongs to the QueH family.
messages: Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr).

216778:DX03 RS03245
gene id: 216778:DX03_RS03245
uniprot id: A0A023XZA0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

216778:DX03 RS05585
gene id: 216778:DX03_RS05585
uniprot id: A0A4U3GD24
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Cell inner membrane
messages: Homoheptamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mechanosensitive channel that participates in the regulation of osmotic pressure changes within the cell, opening in response to stretch forces in the membrane lipid bilayer, without the need for other proteins. Contributes to normal resistance to hypoosmotic shock. Forms an ion channel of 1.0 nanosiemens conductance with a slight preference for anions.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

216778:DX03 RS19310
gene id: 216778:DX03_RS19310
uniprot id: A0A023Y8D6
names: Similarity
messages: Belongs to the glutamine synthetase family.

216778:DX03 RS07285
gene id: 216778:DX03_RS07285
uniprot id: A0A023Y2D3
names: Function
messages: E1 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the decarboxylation of 2-oxoglutarate, the first step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).

216778:DX03 RS04440
gene id: 216778:DX03_RS04440
uniprot id: A0A023Y0J6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

216778:DX03 RS14705
gene id: 216778:DX03_RS14705
uniprot id: A0A023Y6G8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

216778:DX03 RS18135
gene id: 216778:DX03_RS18135
uniprot id: A0A023Y8E5
names: Caution
names: Function
names: Similarity
messages: Belongs to the dUTPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

216778:DX03 RS06290
gene id: 216778:DX03_RS06290
uniprot id: A0A023Y1T1
names: Similarity
messages: Belongs to the glycosyl hydrolase 18 family.

216778:DX03 RS07605
gene id: 216778:DX03_RS07605
uniprot id: A0A023Y1U3
names: Function
names: Similarity
messages: Belongs to the EIF-2B alpha/beta/delta subunits family. MtnA subfamily.
messages: Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).

216778:DX03 RS01800
gene id: 216778:DX03_RS01800
uniprot id: A0A023XZ24
names: Similarity
messages: Belongs to the ArsC family.

216778:DX03 RS10840
gene id: 216778:DX03_RS10840
uniprot id: A0A023Y3R7
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP phosphoribosyltransferase family. Long subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Feedback inhibited by histidine.

216778:DX03 RS07235
gene id: 216778:DX03_RS07235
uniprot id: A0A023Y234
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phospholipase A1 family.
messages: Binds 1 Ca(2+) ion per monomer. In the dimeric form the Ca(2+) is bound by different amino acids with binding of each Ca(2+) shared with ligands coming from each monomer. The Ca(2+) ion may have a role in catalysis.
messages: Cell outer membrane
messages: Homodimer; dimerization is reversible, and the dimeric form is the active one.
messages: Hydrolysis of phosphatidylcholine with phospholipase A2 (EC 3.1.1.4) and phospholipase A1 (EC 3.1.1.32) activities.
messages: Membrane

216778:DX03 RS15240
gene id: 216778:DX03_RS15240
uniprot id: A0A023Y6Z9
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

216778:DX03 RS04585
gene id: 216778:DX03_RS04585
uniprot id: A0A023Y020
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

216778:DX03 RS12980
gene id: 216778:DX03_RS12980
uniprot id: A0A023Y4Z1
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

216778:DX03 RS15780
gene id: 216778:DX03_RS15780
uniprot id: A0A023Y774
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

216778:DX03 RS00035
gene id: 216778:DX03_RS00035
uniprot id: A0A023XXS3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

216778:DX03 RS03210
gene id: 216778:DX03_RS03210
uniprot id: A0A023Y055
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

216778:DX03 RS02855
gene id: 216778:DX03_RS02855
uniprot id: A0A023XZZ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell outer membrane

216778:DX03 RS04850
gene id: 216778:DX03_RS04850
uniprot id: A0A023Y079
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily.
messages: Catalyzes the transfer of the alpha-amino group from S-adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only aminotransferase known to utilize SAM as an amino donor.
messages: Cytoplasm
messages: Homodimer.

216778:DX03 RS12630
gene id: 216778:DX03_RS12630
uniprot id: A0A023Y572
names: Subcellular Location Annotation
messages: Membrane

216778:DX03 RS14730
gene id: 216778:DX03_RS14730
uniprot id: A0A023Y6H3
names: Cofactor
names: Similarity
messages: Belongs to the ApbE family.
messages: Magnesium. Can also use manganese.

216778:DX03 RS06885
gene id: 216778:DX03_RS06885
uniprot id: A0A023Y1A5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

216778:DX03 RS06270
gene id: 216778:DX03_RS06270
uniprot id: A0A023Y1J2
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

216778:DX03 RS07320
gene id: 216778:DX03_RS07320
uniprot id: A0A023Y1M0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 1 lipoyl cofactor covalently.
messages: E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).

216778:DX03 RS13370
gene id: 216778:DX03_RS13370
uniprot id: A0A023Y550
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

216778:DX03 RS19455
gene id: 216778:DX03_RS19455
uniprot id: A0A023Y885
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IgaA family.
messages: Cell inner membrane
messages: Membrane

216778:DX03 RS12640
gene id: 216778:DX03_RS12640
uniprot id: A0A023Y4U4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

216778:DX03 RS16920
gene id: 216778:DX03_RS16920
uniprot id: A0A023Y7N1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

216778:DX03 RS13400
gene id: 216778:DX03_RS13400
uniprot id: A0A023Y5W7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxA subfamily.
messages: Cytoplasm
messages: Homotrimer.
messages: Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

216778:DX03 RS03585
gene id: 216778:DX03_RS03585
uniprot id: A0A023Y0B7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Homodimer.

216778:DX03 RS12910
gene id: 216778:DX03_RS12910
uniprot id: A0A023Y5I9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family.
messages: Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system.
messages: The complex is composed of two ATP-binding proteins (PotA), two transmembrane proteins (PotB and PotC) and a solute-binding protein (PotD).

216778:DX03 RS16560
gene id: 216778:DX03_RS16560
uniprot id: A0A023Y7G5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsL family.
messages: Cell inner membrane
messages: Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.
messages: Membrane
messages: Part of a complex composed of FtsB, FtsL and FtsQ.

216778:DX03 RS07745
gene id: 216778:DX03_RS07745
uniprot id: A0A023Y2F4
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAL/histidase family.
messages: Contains an active site 4-methylidene-imidazol-5-one (MIO), which is formed autocatalytically by cyclization and dehydration of residues Ala-Ser-Gly.
messages: Cytoplasm

216778:DX03 RS16715
gene id: 216778:DX03_RS16715
uniprot id: A0A023Y7A7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Cell membrane
messages: Membrane

216778:DX03 RS05185
gene id: 216778:DX03_RS05185
uniprot id: A0A023Y1E2
names: Similarity
messages: Belongs to the citrate synthase family.

216778:DX03 RS13200
gene id: 216778:DX03_RS13200
uniprot id: A0A023Y5E9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.
messages: Belongs to the RNR ribonuclease family. RNase R subfamily.
messages: Cytoplasm

216778:DX03 RS13250
gene id: 216778:DX03_RS13250
uniprot id: A0A023Y531
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 1 subfamily.
messages: Cell membrane
messages: Heterotetramer composed of ParC and ParE.
messages: Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.

216778:DX03 RS15565
gene id: 216778:DX03_RS15565
uniprot id: A0A4U3GHY4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the zinc-containing alcohol dehydrogenase family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the NAD(+)-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate.
messages: Cytoplasm
messages: Homotetramer.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

216778:DX03 RS15740
gene id: 216778:DX03_RS15740
uniprot id: A0A023Y6T1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

216778:DX03 RS16730
gene id: 216778:DX03_RS16730
uniprot id: A0A023Y7N8
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

216778:DX03 RS19980
gene id: 216778:DX03_RS19980
uniprot id: A0A023Y8K3
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

216778:DX03 RS06590
gene id: 216778:DX03_RS06590
uniprot id: A0A023Y143
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

216778:DX03 RS16755
gene id: 216778:DX03_RS16755
uniprot id: A0A023Y7P2
names: Subcellular Location Annotation
messages: Periplasm

216778:DX03 RS06000
gene id: 216778:DX03_RS06000
uniprot id: A0A023Y1N5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methylthiotransferase family. RimO subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein uS12.
messages: Cytoplasm

216778:DX03 RS11660
gene id: 216778:DX03_RS11660
uniprot id: A0A023Y465
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

216778:DX03 RS18490
gene id: 216778:DX03_RS18490
uniprot id: A0A023Y8K4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm
messages: Homodimer.

216778:DX03 RS13105
gene id: 216778:DX03_RS13105
uniprot id: A0A023Y4T2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PstS family.
messages: Part of the ABC transporter complex PstSACB involved in phosphate import.
messages: The complex is composed of two ATP-binding proteins (PstB), two transmembrane proteins (PstC and PstA) and a solute-binding protein (PstS).

216778:DX03 RS16675
gene id: 216778:DX03_RS16675
uniprot id: A0A023Y6X2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

216778:DX03 RS03560
gene id: 216778:DX03_RS03560
uniprot id: A0A023Y0B2
names: Function
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
messages: Catalyzes the reversible oxidative deamination of glutamate to alpha-ketoglutarate and ammonia.

216778:DX03 RS05820
gene id: 216778:DX03_RS05820
uniprot id: A0A023Y1N8
names: Similarity
messages: Belongs to the peptidase U62 family.

216778:DX03 RS14835
gene id: 216778:DX03_RS14835
uniprot id: A0A023Y6J3
names: Similarity
messages: Belongs to the BolA/IbaG family.

216778:DX03 RS04860
gene id: 216778:DX03_RS04860
uniprot id: A0A023Y181
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inositol monophosphatase superfamily. CysQ family.
messages: Cell inner membrane
messages: Converts adenosine-3',5'-bisphosphate (PAP) to AMP.

216778:DX03 RS10335
gene id: 216778:DX03_RS10335
uniprot id: A0A023Y3A5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliQ/MopD/SpaQ family.
messages: Membrane

216778:DX03 RS09070
gene id: 216778:DX03_RS09070
uniprot id: A0A023Y3F5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autotransporter-2 (AT-2) (TC 1.B.40) family.
messages: Cell surface

216778:DX03 RS07400
gene id: 216778:DX03_RS07400
uniprot id: A0A023Y1W5
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

216778:DX03 RS03740
gene id: 216778:DX03_RS03740
uniprot id: A0A023XZI6
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

216778:DX03 RS13130
gene id: 216778:DX03_RS13130
uniprot id: A0A023Y4T6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

216778:DX03 RS19555
gene id: 216778:DX03_RS19555
uniprot id: A0A023Y8A4
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TtcA family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is chelated by three Cys residues, the fourth Fe has a free coordination site that may bind a sulfur atom transferred from the persulfide of IscS.
messages: Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system.
messages: Cytoplasm
messages: Homodimer.
messages: The thiolation reaction likely consists of two steps: a first activation step by ATP to form an adenylated intermediate of the target base of tRNA, and a second nucleophilic substitution step of the sulfur (S) atom supplied by the hydrosulfide attached to the Fe-S cluster.

216778:DX03 RS04505
gene id: 216778:DX03_RS04505
uniprot id: A0A023Y080
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.

216778:DX03 RS10630
gene id: 216778:DX03_RS10630
uniprot id: A0A023Y404
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

216778:DX03 RS16915
gene id: 216778:DX03_RS16915
uniprot id: A0A023Y7S5
names: Similarity
messages: Belongs to the UPF0057 (PMP3) family.

216778:DX03 RS14650
gene id: 216778:DX03_RS14650
uniprot id: A0A023Y6J8
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

216778:DX03 RS13895
gene id: 216778:DX03_RS13895
uniprot id: A0A023Y5S0
names: Similarity
messages: Belongs to the heat shock protein 90 family.

216778:DX03 RS20190
gene id: 216778:DX03_RS20190
uniprot id: A0A023Y987
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell outer membrane

216778:DX03 RS12655
gene id: 216778:DX03_RS12655
uniprot id: A0A023Y5F5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

216778:DX03 RS03270
gene id: 216778:DX03_RS03270
uniprot id: A0A023XZA3
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.

216778:DX03 RS12265
gene id: 216778:DX03_RS12265
uniprot id: A0A023Y593
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Mediates global changes in gene expression, shifting from rapid growth to stress survival by linking envelope stress, the stringent response and the catabolite repression systems. Usually binds in the 5'-UTR; binding at or near the Shine-Dalgarno sequence prevents ribosome-binding, repressing translation, binding elsewhere in the 5'-UTR can activate translation and/or stabilize the mRNA. Its function is antagonized by small RNA(s).
messages: Belongs to the CsrA/RsmA family.
messages: Cytoplasm
messages: Homodimer; the beta-strands of each monomer intercalate to form a hydrophobic core, while the alpha-helices form wings that extend away from the core.

216778:DX03 RS15870
gene id: 216778:DX03_RS15870
uniprot id: A0A023Y6A7
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

216778:DX03 RS19600
gene id: 216778:DX03_RS19600
uniprot id: A0A023Y8V4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. UvrD subfamily.
messages: Homodimer.
messages: Rep helicase is a single-stranded DNA-dependent ATPase involved in DNA replication; it can initiate unwinding at a nick in the DNA. It binds to the single-stranded DNA and acts in a progressive fashion along the DNA in the 3' to 5' direction.

216778:DX03 RS18505
gene id: 216778:DX03_RS18505
uniprot id: A0A023Y7Z3
names: Similarity
messages: Belongs to the EcnA/EcnB lipoprotein family.

216778:DX03 RS02850
gene id: 216778:DX03_RS02850
uniprot id: A0A023Y025
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

216778:DX03 RS17875
gene id: 216778:DX03_RS17875
uniprot id: A0A023Y823
names: Function
names: Similarity
messages: Belongs to the DHNA family.
messages: Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin.

216778:DX03 RS00775
gene id: 216778:DX03_RS00775
uniprot id: A0A023XYT1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

216778:DX03 RS07180
gene id: 216778:DX03_RS07180
uniprot id: A0A023Y2A7
names: Similarity
messages: Belongs to the glutathione peroxidase family.

216778:DX03 RS10205
gene id: 216778:DX03_RS10205
uniprot id: A0A023Y3U6
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Secreted

216778:DX03 RS02200
gene id: 216778:DX03_RS02200
uniprot id: A0A023XZM2
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

216778:DX03 RS03315
gene id: 216778:DX03_RS03315
uniprot id: A0A023XZW6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

216778:DX03 RS12020
gene id: 216778:DX03_RS12020
uniprot id: A0A023Y503
names: Similarity
messages: Belongs to the SdhE FAD assembly factor family.

216778:DX03 RS00795
gene id: 216778:DX03_RS00795
uniprot id: A0A023XYV4
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily.
messages: Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl-L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway.

216778:DX03 RS12435
gene id: 216778:DX03_RS12435
uniprot id: A0A023Y4F5
names: Subcellular Location Annotation
messages: Membrane

216778:DX03 RS00515
gene id: 216778:DX03_RS00515
uniprot id: A0A023XYR2
names: Cofactor
names: Similarity
messages: Belongs to the RtcB family.
messages: Binds 2 manganese ions per subunit.

216778:DX03 RS12480
gene id: 216778:DX03_RS12480
uniprot id: A0A023Y524
names: Similarity
messages: Belongs to the glutamate synthase family.

216778:DX03 RS18565
gene id: 216778:DX03_RS18565
uniprot id: A0A023Y8S4
names: Subcellular Location Annotation
messages: Membrane

216778:DX03 RS17470
gene id: 216778:DX03_RS17470
uniprot id: A0A023Y802
names: Subcellular Location Annotation
messages: Membrane

216778:DX03 RS13065
gene id: 216778:DX03_RS13065
uniprot id: A0A023Y5R4
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

216778:DX03 RS02135
gene id: 216778:DX03_RS02135
uniprot id: A0A023XYP1
names: Similarity
messages: Belongs to the peptidase S49 family.

216778:DX03 RS15890
gene id: 216778:DX03_RS15890
uniprot id: A0A023Y6I5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

216778:DX03 RS10065
gene id: 216778:DX03_RS10065
uniprot id: A0A023Y3F3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ClpS family.
messages: Binds to the N-terminal domain of the chaperone ClpA.
messages: Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation.

216778:DX03 RS13810
gene id: 216778:DX03_RS13810
uniprot id: A0A023Y630
names: Caution
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the peroxidase family. Peroxidase/catalase subfamily.
messages: Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per dimer.
messages: Formation of the three residue Trp-Tyr-Met cross-link is important for the catalase, but not the peroxidase activity of the enzyme.
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

216778:DX03 RS01745
gene id: 216778:DX03_RS01745
uniprot id: A0A023XZC4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. PrmA family.
messages: Cytoplasm
messages: Methylates ribosomal protein L11.

216778:DX03 RS16530
gene id: 216778:DX03_RS16530
uniprot id: A0A023Y7J8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

216778:DX03 RS08650
gene id: 216778:DX03_RS08650
uniprot id: A0A023Y342
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the quinone-dependent D-lactate dehydrogenase family.
messages: Catalyzes the oxidation of D-lactate to pyruvate.
messages: Cell inner membrane

216778:DX03 RS00565
gene id: 216778:DX03_RS00565
uniprot id: A0A023XYS1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell inner membrane
messages: Membrane

216778:DX03 RS11495
gene id: 216778:DX03_RS11495
uniprot id: A0A023Y4N9
names: Similarity
messages: Belongs to the OprB family.

216778:DX03 RS12760
gene id: 216778:DX03_RS12760
uniprot id: A0A023Y5H0
names: Similarity
messages: Belongs to the GST superfamily. HSP26 family.

216778:DX03 RS09570
gene id: 216778:DX03_RS09570
uniprot id: A0A023Y3D1
names: Similarity
messages: Belongs to the TPP enzyme family.

216778:DX03 RS06960
gene id: 216778:DX03_RS06960
uniprot id: A0A023Y1L4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmF/CycK/Ccl1/NrfE/CcsA family.
messages: Cell inner membrane
messages: Membrane

216778:DX03 RS00530
gene id: 216778:DX03_RS00530
uniprot id: A0A023XXT3
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

216778:DX03 RS07535
gene id: 216778:DX03_RS07535
uniprot id: A0A023Y2Q1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

216778:DX03 RS03475
gene id: 216778:DX03_RS03475
uniprot id: A0A023XZL5
names: Similarity
messages: In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.
messages: In the N-terminal section; belongs to the malic enzymes family.

216778:DX03 RS02700
gene id: 216778:DX03_RS02700
uniprot id: A0A023Y002
names: Function
names: Similarity
messages: A cysteine desulfhydrase that generates hydrogen sulfide, H(2)S. The H(2)S produced by this enzyme may modulate central metabolism.
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family. Cds1 subfamily.

216778:DX03 RS01365
gene id: 216778:DX03_RS01365
uniprot id: A0A023XYT0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate synthase component I family.
messages: Heterotetramer consisting of two non-identical subunits: a beta subunit (TrpG) and a large alpha subunit (TrpE).
messages: Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia.

216778:DX03 RS16635
gene id: 216778:DX03_RS16635
uniprot id: A0A023Y7H6
names: Caution
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the thiamine-monophosphate kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate.

216778:DX03 RS17195
gene id: 216778:DX03_RS17195
uniprot id: A0A023Y7U5
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

216778:DX03 RS06625
gene id: 216778:DX03_RS06625
uniprot id: A0A023Y233
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

216778:DX03 RS04830
gene id: 216778:DX03_RS04830
uniprot id: A0A023Y126
names: Function
messages: Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors. CheA is autophosphorylated; it can transfer its phosphate group to either CheB or CheY.

216778:DX03 RS08040
gene id: 216778:DX03_RS08040
uniprot id: A0A023Y2Y4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

216778:DX03 RS16420
gene id: 216778:DX03_RS16420
uniprot id: A0A023Y6J7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PEPCase type 1 family.
messages: Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.
messages: Homotetramer.

216778:DX03 RS16055
gene id: 216778:DX03_RS16055
uniprot id: A0A023Y7B5
names: Function
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

216778:DX03 RS10045
gene id: 216778:DX03_RS10045
uniprot id: A0A023Y435
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

216778:DX03 RS06275
gene id: 216778:DX03_RS06275
uniprot id: A0A023Y0Y0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

216778:DX03 RS01995
gene id: 216778:DX03_RS01995
uniprot id: A0A023XZJ0
names: Similarity
messages: Belongs to the GST superfamily.

216778:DX03 RS19665
gene id: 216778:DX03_RS19665
uniprot id: A0A023Y9C8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

216778:DX03 RS10280
gene id: 216778:DX03_RS10280
uniprot id: A0A023Y3V5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the FliF family.
messages: Membrane
messages: The M ring may be actively involved in energy transduction.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The M ring is integral to the inner membrane of the cell and may be connected to the flagellar rod via the S ring. The S (supramembrane ring) lies just distal to the M ring. The L and P rings lie in the outer membrane and the periplasmic space, respectively.

216778:DX03 RS03150
gene id: 216778:DX03_RS03150
uniprot id: A0A023XZF5
names: Function
names: Similarity
messages: Belongs to the GMC oxidoreductase family.
messages: Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate.

216778:DX03 RS09395
gene id: 216778:DX03_RS09395
uniprot id: A0A023Y2N1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC13A/DASS transporter (TC 2.A.47) family. DIT1 subfamily.
messages: Membrane

216778:DX03 RS02595
gene id: 216778:DX03_RS02595
uniprot id: A0A023XZ69
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family. T3SS ATPase subfamily.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

216778:DX03 RS07100
gene id: 216778:DX03_RS07100
uniprot id: A0A023Y292
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NfuA family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is presumably bound at the interface of two monomers.
messages: Homodimer.
messages: Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins.

216778:DX03 RS00245
gene id: 216778:DX03_RS00245
uniprot id: A0A023XYI8
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

216778:DX03 RS03080
gene id: 216778:DX03_RS03080
uniprot id: A0A023Y034
names: Cofactor
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. NagA family.
messages: Binds 1 divalent metal cation per subunit.

216778:DX03 RS07210
gene id: 216778:DX03_RS07210
uniprot id: A0A023Y227
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I fumarase family.
messages: Catalyzes the reversible hydration of fumarate to (S)-malate.
messages: Homodimer.

216778:DX03 RS08170
gene id: 216778:DX03_RS08170
uniprot id: A0A023Y304
names: Cofactor
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.
messages: Probably binds two magnesium or manganese ions per subunit.

216778:DX03 RS11485
gene id: 216778:DX03_RS11485
uniprot id: A0A023Y427
names: Subcellular Location Annotation
messages: Membrane

216778:DX03 RS11335
gene id: 216778:DX03_RS11335
uniprot id: A0A023Y400
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial histone-like protein family.
messages: Heterodimer of an alpha and a beta chain.
messages: This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.

216778:DX03 RS11975
gene id: 216778:DX03_RS11975
uniprot id: A0A023Y4R4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the heat shock protein 90 family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Molecular chaperone. Has ATPase activity.

216778:DX03 RS02175
gene id: 216778:DX03_RS02175
uniprot id: A0A023XZL7
names: Similarity
messages: Belongs to the N-Me-Phe pilin family.

216778:DX03 RS18065
gene id: 216778:DX03_RS18065
uniprot id: A0A023Y846
names: Subcellular Location Annotation
messages: Membrane

216778:DX03 RS01780
gene id: 216778:DX03_RS01780
uniprot id: A0A023XYF4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

216778:DX03 RS16845
gene id: 216778:DX03_RS16845
uniprot id: A0A023Y7D3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Cell inner membrane
messages: Membrane

216778:DX03 RS13300
gene id: 216778:DX03_RS13300
uniprot id: A0A023Y539
names: Activity Regulation
names: Domain
names: Function
names: Similarity
messages: Belongs to the GlnD family.
messages: Has four distinct domains: an N-terminal nucleotidyltransferase (NT) domain responsible for UTase activity, a central HD domain that encodes UR activity, and two C-terminal ACT domains that seem to have a role in glutamine sensing.
messages: Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen metabolism.
messages: Uridylyltransferase (UTase) activity is inhibited by glutamine, while glutamine activates uridylyl-removing (UR) activity.

216778:DX03 RS00335
gene id: 216778:DX03_RS00335
uniprot id: A0A023XXX1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

216778:DX03 RS13840
gene id: 216778:DX03_RS13840
uniprot id: A0A023Y5Z5
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

216778:DX03 RS04330
gene id: 216778:DX03_RS04330
uniprot id: A0A023Y0V5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

216778:DX03 RS16130
gene id: 216778:DX03_RS16130
uniprot id: A0A023Y7C7
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

216778:DX03 RS18710
gene id: 216778:DX03_RS18710
uniprot id: A0A023Y824
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 independent methionine synthase family.
messages: Binds 1 zinc ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine resulting in methionine formation.

216778:DX03 RS09370
gene id: 216778:DX03_RS09370
uniprot id: A0A023Y2M6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

216778:DX03 RS04745
gene id: 216778:DX03_RS04745
uniprot id: A0A023Y0C5
names: Similarity
messages: Belongs to the helicase family. RecQ subfamily.

216778:DX03 RS15825
gene id: 216778:DX03_RS15825
uniprot id: A0A023Y6I5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

216778:DX03 RS18770
gene id: 216778:DX03_RS18770
uniprot id: A0A023Y8Q2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.
messages: Binds 2 iron ions per subunit.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

216778:DX03 RS08935
gene id: 216778:DX03_RS08935
uniprot id: A0A023Y2E8
names: Similarity
messages: Belongs to the VgrG protein family.

216778:DX03 RS11695
gene id: 216778:DX03_RS11695
uniprot id: A0A023Y4S8
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Fur family.
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.

216778:DX03 RS10590
gene id: 216778:DX03_RS10590
uniprot id: A0A023Y3N2
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

216778:DX03 RS16510
gene id: 216778:DX03_RS16510
uniprot id: A0A023Y7F5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.
messages: Cell membrane
messages: Self-interacts. Interacts with FtsZ.

216778:DX03 RS17930
gene id: 216778:DX03_RS17930
uniprot id: A0A023Y7J0
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
messages: Carbon 2 of the heme B porphyrin ring is defined according to the Fischer nomenclature.
messages: Cell membrane
messages: Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
messages: Membrane

216778:DX03 RS02925
gene id: 216778:DX03_RS02925
uniprot id: A0A023Y038
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MreD family.
messages: Cell inner membrane
messages: Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins.
messages: Membrane

216778:DX03 RS02950
gene id: 216778:DX03_RS02950
uniprot id: A0A023Y042
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RlpA family.
messages: Cell membrane
messages: Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides.

216778:DX03 RS21465
gene id: 216778:DX03_RS21465
uniprot id: A0A023XZW2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

216778:DX03 RS01305
gene id: 216778:DX03_RS01305
uniprot id: A0A023XZ27
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit E family.
messages: Cell membrane
messages: Membrane

216778:DX03 RS14155
gene id: 216778:DX03_RS14155
uniprot id: A0A023Y5W8
names: Function
names: Similarity
names: Subunit
messages: ATPase required for the correct placement of the division site. Cell division inhibitors MinC and MinD act in concert to form an inhibitor capable of blocking formation of the polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings.
messages: Belongs to the ParA family. MinD subfamily.
messages: Interacts with MinC and FtsZ.

216778:DX03 RS10480
gene id: 216778:DX03_RS10480
uniprot id: A0A023Y3Y4
names: Function
names: Similarity
messages: Belongs to the CheD family.
messages: Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis.

216778:DX03 RS06505
gene id: 216778:DX03_RS06505
uniprot id: A0A023Y1N6
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

216778:DX03 RS20015
gene id: 216778:DX03_RS20015
uniprot id: A0A023Y9K6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Cell membrane
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

216778:DX03 RS08585
gene id: 216778:DX03_RS08585
uniprot id: A0A023Y285
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

216778:DX03 RS04615
gene id: 216778:DX03_RS04615
uniprot id: A0A023Y098
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ExbB/TolQ family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

216778:DX03 RS11835
gene id: 216778:DX03_RS11835
uniprot id: A0A023Y4A4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

216778:DX03 RS16280
gene id: 216778:DX03_RS16280
uniprot id: A0A023Y7F2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LemA family.
messages: Membrane

216778:DX03 RS02810
gene id: 216778:DX03_RS02810
uniprot id: A0A023XZN8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.

216778:DX03 RS03700
gene id: 216778:DX03_RS03700
uniprot id: A0A023Y0G9
names: Subcellular Location Annotation
messages: Cell inner membrane

216778:DX03 RS08080
gene id: 216778:DX03_RS08080
uniprot id: A0A023Y211
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial diacylglycerol kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of sn-l,2-diacylglycerol (DAG) to phosphatidic acid. Involved in the recycling of diacylglycerol produced as a by-product during membrane-derived oligosaccharide (MDO) biosynthesis.
messages: Cell inner membrane
messages: Membrane
messages: Mn(2+), Zn(2+), Cd(2+) and Co(2+) support activity to lesser extents.

216778:DX03 RS04845
gene id: 216778:DX03_RS04845
uniprot id: A0A023Y0U0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

216778:DX03 RS18085
gene id: 216778:DX03_RS18085
uniprot id: A0A023Y8D8
names: Cofactor
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.
messages: Probably binds two magnesium or manganese ions per subunit.

216778:DX03 RS19090
gene id: 216778:DX03_RS19090
uniprot id: A0A023Y909
names: Function
messages: TetR is the repressor of the tetracycline resistance element; its N-terminal region forms a helix-turn-helix structure and binds DNA. Binding of tetracycline to TetR reduces the repressor affinity for the tetracycline resistance gene (tetA) promoter operator sites.

216778:DX03 RS17110
gene id: 216778:DX03_RS17110
uniprot id: A0A023Y768
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

216778:DX03 RS18740
gene id: 216778:DX03_RS18740
uniprot id: A0A023Y8U9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

216778:DX03 RS15790
gene id: 216778:DX03_RS15790
uniprot id: A0A023Y6T7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

216778:DX03 RS13385
gene id: 216778:DX03_RS13385
uniprot id: A0A023Y5H6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamA family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

216778:DX03 RS12390
gene id: 216778:DX03_RS12390
uniprot id: A0A023Y5C5
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Component of the RNA degradosome, which is a multiprotein complex involved in RNA processing and mRNA degradation.
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

216778:DX03 RS09855
gene id: 216778:DX03_RS09855
uniprot id: A0A023Y3J7
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

216778:DX03 RS13425
gene id: 216778:DX03_RS13425
uniprot id: A0A023Y5X2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccA family.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

216778:DX03 RS07985
gene id: 216778:DX03_RS07985
uniprot id: A0A023Y281
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

216778:DX03 RS01555
gene id: 216778:DX03_RS01555
uniprot id: A0A023XYA9
names: Cofactor
names: Similarity
messages: Belongs to the monomeric-type IDH family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

216778:DX03 RS17375
gene id: 216778:DX03_RS17375
uniprot id: A0A023Y7N9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DoxX family.
messages: Membrane

216778:DX03 RS12985
gene id: 216778:DX03_RS12985
uniprot id: A0A023Y5Q2
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

216778:DX03 RS20065
gene id: 216778:DX03_RS20065
uniprot id: A0A023Y9L5
names: Subcellular Location Annotation
messages: Membrane

216778:DX03 RS09305
gene id: 216778:DX03_RS09305
uniprot id: A0A023Y3K6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

216778:DX03 RS07035
gene id: 216778:DX03_RS07035
uniprot id: A0A023Y1N3
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

216778:DX03 RS17130
gene id: 216778:DX03_RS17130
uniprot id: A0A023Y6Y7
names: Similarity
messages: Belongs to the GSP E family.

216778:DX03 RS17755
gene id: 216778:DX03_RS17755
uniprot id: A0A023Y7E2
names: Function
names: Similarity
messages: Belongs to the GlnE family.
messages: Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell.

216778:DX03 RS04765
gene id: 216778:DX03_RS04765
uniprot id: A0A023Y062
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

216778:DX03 RS02210
gene id: 216778:DX03_RS02210
uniprot id: A0A023XYR1
names: Subcellular Location Annotation
messages: Membrane

216778:DX03 RS05905
gene id: 216778:DX03_RS05905
uniprot id: A0A023Y1B7
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

216778:DX03 RS15480
gene id: 216778:DX03_RS15480
uniprot id: A0A023Y6Y0
names: Function
messages: Member of the two-component regulatory system PhoR/PhoB involved in the phosphate regulon genes expression. PhoR may function as a membrane-associated protein kinase that phosphorylates PhoB in response to environmental signals.

216778:DX03 RS12715
gene id: 216778:DX03_RS12715
uniprot id: A0A023Y583
names: Similarity
messages: Belongs to the glutaredoxin family. Monothiol subfamily.

216778:DX03 RS19865
gene id: 216778:DX03_RS19865
uniprot id: A0A023Y9A5
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.

216778:DX03 RS11345
gene id: 216778:DX03_RS11345
uniprot id: A0A023Y4K9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

216778:DX03 RS17015
gene id: 216778:DX03_RS17015
uniprot id: A0A023Y7U8
names: Similarity
messages: Belongs to the mannose-6-phosphate isomerase type 2 family.

216778:DX03 RS10405
gene id: 216778:DX03_RS10405
uniprot id: A0A023Y3X4
names: Function
messages: Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors. CheA is autophosphorylated; it can transfer its phosphate group to either CheB or CheY.

216778:DX03 RS05545
gene id: 216778:DX03_RS05545
uniprot id: A0A023Y1F6
names: Function
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
messages: Catalyzes the reversible oxidative deamination of glutamate to alpha-ketoglutarate and ammonia.

216778:DX03 RS02920
gene id: 216778:DX03_RS02920
uniprot id: A0A023XZC0
names: Similarity
messages: Belongs to the MreC family.

216778:DX03 RS02590
gene id: 216778:DX03_RS02590
uniprot id: A0A023XYZ5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

216778:DX03 RS08970
gene id: 216778:DX03_RS08970
uniprot id: A0A023Y3D6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

216778:DX03 RS05250
gene id: 216778:DX03_RS05250
uniprot id: A0A023Y0G2
names: Function
names: Similarity
messages: Belongs to the band 7/mec-2 family. HflC subfamily.
messages: HflC and HflK could regulate a protease.

216778:DX03 RS09830
gene id: 216778:DX03_RS09830
uniprot id: A0A023Y3J1
names: Subcellular Location Annotation
messages: Membrane

216778:DX03 RS03895
gene id: 216778:DX03_RS03895
uniprot id: A0A023XZU2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

216778:DX03 RS17100
gene id: 216778:DX03_RS17100
uniprot id: A0A023Y7H8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell inner membrane
messages: Membrane

216778:DX03 RS18365
gene id: 216778:DX03_RS18365
uniprot id: A0A023Y884
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

216778:DX03 RS17695
gene id: 216778:DX03_RS17695
uniprot id: A0A023Y857
names: Similarity
messages: Belongs to the SIP oxidoreductase family.

216778:DX03 RS03650
gene id: 216778:DX03_RS03650
uniprot id: A0A023Y036
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PPase family.
messages: Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
messages: Cytoplasm
messages: Homohexamer.

216778:DX03 RS10620
gene id: 216778:DX03_RS10620
uniprot id: A0A023Y4C9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Probable transporter of a GTP-driven Fe(2+) uptake system.

216778:DX03 RS14845
gene id: 216778:DX03_RS14845
uniprot id: A0A023Y5Q4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the KdsC family.
messages: Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate.
messages: Homotetramer.

216778:DX03 RS12430
gene id: 216778:DX03_RS12430
uniprot id: A0A023Y512
names: Similarity
messages: Belongs to the UPF0111 family.

216778:DX03 RS03685
gene id: 216778:DX03_RS03685
uniprot id: A0A023Y041
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

216778:DX03 RS00620
gene id: 216778:DX03_RS00620
uniprot id: A0A023XYQ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane
messages: Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins.

216778:DX03 RS16880
gene id: 216778:DX03_RS16880
uniprot id: A0A023Y6T5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbC subfamily.
messages: Periplasm
messages: Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process.

216778:DX03 RS15495
gene id: 216778:DX03_RS15495
uniprot id: A0A023Y6D3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

216778:DX03 RS18465
gene id: 216778:DX03_RS18465
uniprot id: A0A023Y8J9
names: Subcellular Location Annotation
messages: Membrane

216778:DX03 RS17380
gene id: 216778:DX03_RS17380
uniprot id: A0A023Y751
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

216778:DX03 RS12770
gene id: 216778:DX03_RS12770
uniprot id: A0A023Y4N7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome b family.
messages: Binds 2 heme groups non-covalently.
messages: Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.
messages: Membrane
messages: The main subunits of complex b-c1 are: cytochrome b, cytochrome c1 and the Rieske protein.

216778:DX03 RS19245
gene id: 216778:DX03_RS19245
uniprot id: A0A023Y8Y3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Cu-Zn superoxide dismutase family.
messages: Binds 1 copper ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

216778:DX03 RS04635
gene id: 216778:DX03_RS04635
uniprot id: A0A023Y033
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TolB family.
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: Periplasm
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

216778:DX03 RS05540
gene id: 216778:DX03_RS05540
uniprot id: A0A023Y1J3
names: Similarity
messages: Belongs to the peptidase S8 family.

216778:DX03 RS13720
gene id: 216778:DX03_RS13720
uniprot id: A0A023Y5N5
names: Subcellular Location Annotation
messages: Membrane

216778:DX03 RS02940
gene id: 216778:DX03_RS02940
uniprot id: A0A023XZ48
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEDS family. MrdB/RodA subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Peptidoglycan polymerase that is essential for cell wall elongation.

216778:DX03 RS16135
gene id: 216778:DX03_RS16135
uniprot id: A0A023Y789
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

216778:DX03 RS11670
gene id: 216778:DX03_RS11670
uniprot id: A0A023Y4S5
names: Function
names: Similarity
messages: Belongs to the HrcA family.
messages: Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons.

216778:DX03 RS17865
gene id: 216778:DX03_RS17865
uniprot id: A0A023Y8G9
names: Similarity
messages: Belongs to the glycosyl hydrolase 3 family.

216778:DX03 RS02975
gene id: 216778:DX03_RS02975
uniprot id: A0A023Y048
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

216778:DX03 RS19305
gene id: 216778:DX03_RS19305
uniprot id: A0A023Y855
names: Similarity
messages: Belongs to the P(II) protein family.

216778:DX03 RS15820
gene id: 216778:DX03_RS15820
uniprot id: A0A023Y699
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

216778:DX03 RS01075
gene id: 216778:DX03_RS01075
uniprot id: A0A023XZ04
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

216778:DX03 RS07095
gene id: 216778:DX03_RS07095
uniprot id: A0A023Y2D4
names: Similarity
messages: Belongs to the pterin-4-alpha-carbinolamine dehydratase family.

216778:DX03 RS04075
gene id: 216778:DX03_RS04075
uniprot id: A0A023Y0Q1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family.
messages: Binds 1 Mg(2+) ion per subunit. Can also utilize other divalent metal cations, such as Ca(2+), Mn(2+) and Co(2+).
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
messages: Homodimer.

216778:DX03 RS13915
gene id: 216778:DX03_RS13915
uniprot id: A0A023Y609
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Cytochrome bo(3) ubiquinol terminal oxidase is the component of the aerobic respiratory chain of E.coli that predominates when cells are grown at high aeration. Has proton pump activity across the membrane in addition to electron transfer, pumping 2 protons/electron.
messages: Heterooctamer of two A chains, two B chains, two C chains and two D chains.
messages: Membrane

216778:DX03 RS01695
gene id: 216778:DX03_RS01695
uniprot id: A0A023XZB2
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

216778:DX03 RS06635
gene id: 216778:DX03_RS06635
uniprot id: A0A023Y1Q8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueG family.
messages: Binds 2 [4Fe-4S] clusters per monomer.
messages: Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

216778:DX03 RS05915
gene id: 216778:DX03_RS05915
uniprot id: A0A023Y0Z2
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

216778:DX03 RS18545
gene id: 216778:DX03_RS18545
uniprot id: A0A4U3G866
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

216778:DX03 RS09020
gene id: 216778:DX03_RS09020
uniprot id: A0A023Y3E5
names: Subcellular Location Annotation
messages: Membrane

216778:DX03 RS11340
gene id: 216778:DX03_RS11340
uniprot id: A0A023Y4P8
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS1 family.
messages: Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence.

216778:DX03 RS07920
gene id: 216778:DX03_RS07920
uniprot id: A0A023Y2S1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

216778:DX03 RS15485
gene id: 216778:DX03_RS15485
uniprot id: A0A023Y6P4
names: Function
names: PTM
names: Similarity
messages: An intermediate of this reaction is the autophosphorylated ppk in which a phosphate is covalently linked to a histidine residue through a N-P bond.
messages: Belongs to the polyphosphate kinase 1 (PPK1) family.
messages: Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP).

216778:DX03 RS03445
gene id: 216778:DX03_RS03445
uniprot id: A0A023XZD7
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

216778:DX03 RS12720
gene id: 216778:DX03_RS12720
uniprot id: A0A023Y4N0
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

216778:DX03 RS02180
gene id: 216778:DX03_RS02180
uniprot id: A0A023XZB5
names: Similarity
messages: Belongs to the Smg family.

216778:DX03 RS16035
gene id: 216778:DX03_RS16035
uniprot id: A0A023Y772
names: Function
names: Similarity
messages: Acts on leucine, isoleucine and valine.
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

216778:DX03 RS09455
gene id: 216778:DX03_RS09455
uniprot id: A0A023Y3P1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MgtC/SapB family.
messages: Cell inner membrane
messages: Membrane

216778:DX03 RS00305
gene id: 216778:DX03_RS00305
uniprot id: A0A023XXP3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the aerobic coproporphyrinogen-III oxidase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX.

216778:DX03 RS05310
gene id: 216778:DX03_RS05310
uniprot id: A0A023Y0P9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Bcr/CmlA family.
messages: Cell inner membrane
messages: Membrane

216778:DX03 RS17985
gene id: 216778:DX03_RS17985
uniprot id: A0A023Y7S6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OmpP1/FadL family.
messages: Cell outer membrane
messages: Membrane

216778:DX03 RS14435
gene id: 216778:DX03_RS14435
uniprot id: A0A023Y5F8
names: Subcellular Location Annotation
messages: Membrane

216778:DX03 RS15950
gene id: 216778:DX03_RS15950
uniprot id: A0A023Y798
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

216778:DX03 RS04535
gene id: 216778:DX03_RS04535
uniprot id: A0A023Y103
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

216778:DX03 RS10175
gene id: 216778:DX03_RS10175
uniprot id: A0A023Y420
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.

216778:DX03 RS19085
gene id: 216778:DX03_RS19085
uniprot id: A0A023Y893
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

216778:DX03 RS11425
gene id: 216778:DX03_RS11425
uniprot id: A0A023Y4F7
names: Similarity
messages: Belongs to the DEAD box helicase family.

216778:DX03 RS17445
gene id: 216778:DX03_RS17445
uniprot id: A0A023Y7Z6
names: Similarity
messages: Belongs to the YciI family.

216778:DX03 RS00030
gene id: 216778:DX03_RS00030
uniprot id: A0A023XXK6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatB family.
messages: Cell membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

216778:DX03 RS18755
gene id: 216778:DX03_RS18755
uniprot id: A0A023Y7V4
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

216778:DX03 RS12040
gene id: 216778:DX03_RS12040
uniprot id: A0A023Y547
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome b560 family.
messages: Membrane
messages: Membrane-anchoring subunit of succinate dehydrogenase (SDH).
messages: Part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur protein, plus two membrane-anchoring proteins, SdhC and SdhD. The complex can form homotrimers.
messages: The heme is bound between the two transmembrane subunits.

216778:DX03 RS01770
gene id: 216778:DX03_RS01770
uniprot id: A0A023XZD0
names: Function
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

216778:DX03 RS14410
gene id: 216778:DX03_RS14410
uniprot id: A0A023Y5F3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

216778:DX03 RS07585
gene id: 216778:DX03_RS07585
uniprot id: A0A023Y222
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

216778:DX03 RS01940
gene id: 216778:DX03_RS01940
uniprot id: A0A023XZH8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

216778:DX03 RS03320
gene id: 216778:DX03_RS03320
uniprot id: A0A023XZB4
names: Subcellular Location Annotation
messages: Membrane

216778:DX03 RS02055
gene id: 216778:DX03_RS02055
uniprot id: A0A023XZ86
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0126 family.
messages: Membrane

216778:DX03 RS03140
gene id: 216778:DX03_RS03140
uniprot id: A0A4U3GIQ1
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

216778:DX03 RS03170
gene id: 216778:DX03_RS03170
uniprot id: A0A023XZ87
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbA subfamily.
messages: Periplasm

216778:DX03 RS01420
gene id: 216778:DX03_RS01420
uniprot id: A0A023XY88
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

216778:DX03 RS16430
gene id: 216778:DX03_RS16430
uniprot id: A0A023Y7H7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.
messages: Cytoplasm
messages: May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.

216778:DX03 RS15040
gene id: 216778:DX03_RS15040
uniprot id: A0A023Y6F5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

216778:DX03 RS03110
gene id: 216778:DX03_RS03110
uniprot id: A0A023XZT0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

216778:DX03 RS03715
gene id: 216778:DX03_RS03715
uniprot id: A0A023XZI1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

216778:DX03 RS08155
gene id: 216778:DX03_RS08155
uniprot id: A0A023Y2K9
names: Subcellular Location Annotation
messages: Membrane

216778:DX03 RS05340
gene id: 216778:DX03_RS05340
uniprot id: A0A023Y1G4
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

216778:DX03 RS13355
gene id: 216778:DX03_RS13355
uniprot id: A0A023Y5R3
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Inhibited by UTP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

216778:DX03 RS05420
gene id: 216778:DX03_RS05420
uniprot id: A0A023Y1D5
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

216778:DX03 RS16875
gene id: 216778:DX03_RS16875
uniprot id: A0A023Y7D7
names: Similarity
messages: Belongs to the glycosyl hydrolase 18 family. Chitinase class II subfamily.

216778:DX03 RS18735
gene id: 216778:DX03_RS18735
uniprot id: A0A023Y829
names: Function
messages: Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).

216778:DX03 RS07395
gene id: 216778:DX03_RS07395
uniprot id: A0A023Y1N7
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

216778:DX03 RS17040
gene id: 216778:DX03_RS17040
uniprot id: A0A023Y7V6
names: Similarity
messages: Belongs to the ETF beta-subunit/FixA family.

216778:DX03 RS02095
gene id: 216778:DX03_RS02095
uniprot id: A0A023XZL3
names: Similarity
messages: Belongs to the NADH dehydrogenase family.

216778:DX03 RS01765
gene id: 216778:DX03_RS01765
uniprot id: A0A023XZE3
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

216778:DX03 RS13335
gene id: 216778:DX03_RS13335
uniprot id: A0A023Y5G7
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

216778:DX03 RS15190
gene id: 216778:DX03_RS15190
uniprot id: A0A023Y6Z0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

216778:DX03 RS03755
gene id: 216778:DX03_RS03755
uniprot id: A0A023Y0E8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Membrane

216778:DX03 RS03605
gene id: 216778:DX03_RS03605
uniprot id: A0A023Y0F6
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

216778:DX03 RS18175
gene id: 216778:DX03_RS18175
uniprot id: A0A023Y7U6
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

216778:DX03 RS09030
gene id: 216778:DX03_RS09030
uniprot id: A0A023Y323
names: Similarity
messages: Belongs to the GSP E family.

216778:DX03 RS14175
gene id: 216778:DX03_RS14175
uniprot id: A0A023Y657
names: Similarity
messages: Belongs to the peptidase S9C family.

216778:DX03 RS06030
gene id: 216778:DX03_RS06030
uniprot id: A0A023Y1E4
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Prokaryotic type I sub-subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
messages: Cell membrane
messages: Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The autoendoproteolytic cleavage occurs by a canonical serine protease mechanism, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain. During this reaction, the Ser that is part of the protease active site of the proenzyme becomes the pyruvoyl prosthetic group, which constitutes an essential element of the active site of the mature decarboxylase.

216778:DX03 RS04405
gene id: 216778:DX03_RS04405
uniprot id: A0A023Y0X2
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

216778:DX03 RS20000
gene id: 216778:DX03_RS20000
uniprot id: A0A023Y942
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

216778:DX03 RS15195
gene id: 216778:DX03_RS15195
uniprot id: A0A023Y6U6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

216778:DX03 RS05260
gene id: 216778:DX03_RS05260
uniprot id: A0A023Y1F3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

216778:DX03 RS14495
gene id: 216778:DX03_RS14495
uniprot id: A0A023Y5R5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
messages: Cell inner membrane

216778:DX03 RS10815
gene id: 216778:DX03_RS10815
uniprot id: A0A023Y3R4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

216778:DX03 RS15370
gene id: 216778:DX03_RS15370
uniprot id: A0A023Y716
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

216778:DX03 RS11520
gene id: 216778:DX03_RS11520
uniprot id: A0A023Y4P4
names: Similarity
messages: Belongs to the UPF0178 family.

216778:DX03 RS00820
gene id: 216778:DX03_RS00820
uniprot id: A0A023XYV7
names: Similarity
messages: Belongs to the UPF0167 family.

216778:DX03 RS18595
gene id: 216778:DX03_RS18595
uniprot id: A0A023Y8M2
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

216778:DX03 RS02525
gene id: 216778:DX03_RS02525
uniprot id: A0A023XZX2
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.

216778:DX03 RS12915
gene id: 216778:DX03_RS12915
uniprot id: A0A023Y5B3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein PotD/PotF family.
messages: Periplasm
messages: Required for the activity of the bacterial periplasmic transport system of putrescine.

216778:DX03 RS13910
gene id: 216778:DX03_RS13910
uniprot id: A0A023Y650
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome c oxidase bacterial subunit 4 family.
messages: Cytochrome bo(3) ubiquinol terminal oxidase is the component of the aerobic respiratory chain of E.coli that predominates when cells are grown at high aeration. Has proton pump activity across the membrane in addition to electron transfer, pumping 2 protons/electron.
messages: Heterooctamer of two A chains, two B chains, two C chains and two D chains.
messages: Membrane

216778:DX03 RS10655
gene id: 216778:DX03_RS10655
uniprot id: A0A023Y408
names: Similarity
messages: Belongs to the elongation factor P family.

216778:DX03 RS13360
gene id: 216778:DX03_RS13360
uniprot id: A0A023Y5H1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

216778:DX03 RS15575
gene id: 216778:DX03_RS15575
uniprot id: A0A023Y742
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

216778:DX03 RS11970
gene id: 216778:DX03_RS11970
uniprot id: A0A023Y4Z0
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily. RsmD family.
messages: Specifically methylates the guanine in position 966 of 16S rRNA in the assembled 30S particle.

216778:DX03 RS10780
gene id: 216778:DX03_RS10780
uniprot id: A0A023Y426
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

216778:DX03 RS02655
gene id: 216778:DX03_RS02655
uniprot id: A0A023XZV9
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

216778:DX03 RS07405
gene id: 216778:DX03_RS07405
uniprot id: A0A023Y2K2
names: Similarity
messages: Belongs to the SlyX family.

216778:DX03 RS18635
gene id: 216778:DX03_RS18635
uniprot id: A0A023Y812
names: Subcellular Location Annotation
messages: Membrane

216778:DX03 RS06225
gene id: 216778:DX03_RS06225
uniprot id: A0A023Y1V5
names: Subcellular Location Annotation
messages: Membrane

216778:DX03 RS00025
gene id: 216778:DX03_RS00025
uniprot id: A0A023XY43
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

216778:DX03 RS15030
gene id: 216778:DX03_RS15030
uniprot id: A0A023Y6T4
names: Similarity
messages: Belongs to the Gfa family.

216778:DX03 RS16440
gene id: 216778:DX03_RS16440
uniprot id: A0A023Y750
names: Similarity
messages: Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily.

216778:DX03 RS16290
gene id: 216778:DX03_RS16290
uniprot id: A0A023Y719
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial diacylglycerol kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of sn-l,2-diacylglycerol (DAG) to phosphatidic acid. Involved in the recycling of diacylglycerol produced as a by-product during membrane-derived oligosaccharide (MDO) biosynthesis.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Mn(2+), Zn(2+), Cd(2+) and Co(2+) support activity to lesser extents.

216778:DX03 RS10680
gene id: 216778:DX03_RS10680
uniprot id: A0A023Y411
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

216778:DX03 RS05970
gene id: 216778:DX03_RS05970
uniprot id: A0A023Y1R2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

216778:DX03 RS12900
gene id: 216778:DX03_RS12900
uniprot id: A0A023Y4Y0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

216778:DX03 RS18825
gene id: 216778:DX03_RS18825
uniprot id: A0A4U3GBZ6
names: Caution
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

216778:DX03 RS08625
gene id: 216778:DX03_RS08625
uniprot id: A0A023Y338
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MgtC/SapB family.
messages: Cell inner membrane
messages: Membrane

216778:DX03 RS14190
gene id: 216778:DX03_RS14190
uniprot id: A0A023Y5J8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.
messages: Membrane

216778:DX03 RS07495
gene id: 216778:DX03_RS07495
uniprot id: A0A023Y2B5
names: Cofactor
messages: Binds 2 Mg(2+) ions per monomer.

216778:DX03 RS12465
gene id: 216778:DX03_RS12465
uniprot id: A0A023Y4P0
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

216778:DX03 RS17975
gene id: 216778:DX03_RS17975
uniprot id: A0A023Y838
names: Function
names: Similarity
messages: In the C-terminal section; belongs to the aldehyde dehydrogenase family.
messages: In the N-terminal section; belongs to the proline dehydrogenase family.
messages: Oxidizes proline to glutamate for use as a carbon and nitrogen source.

216778:DX03 RS16900
gene id: 216778:DX03_RS16900
uniprot id: A0A023Y7E1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptF/LptG family.
messages: Cell inner membrane
messages: Component of the lipopolysaccharide transport and assembly complex. The LptBFG transporter is composed of two ATP-binding proteins (LptB) and two transmembrane proteins (LptF and LptG).
messages: Membrane
messages: Part of the ABC transporter complex LptBFG involved in the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane.

216778:DX03 RS14990
gene id: 216778:DX03_RS14990
uniprot id: A0A023Y6E2
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

216778:DX03 RS19960
gene id: 216778:DX03_RS19960
uniprot id: A0A023Y8U0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

216778:DX03 RS15685
gene id: 216778:DX03_RS15685
uniprot id: A0A023Y713
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DsbB family.
messages: Cell inner membrane
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein.

216778:DX03 RS08045
gene id: 216778:DX03_RS08045
uniprot id: A0A023Y2U2
names: Subcellular Location Annotation
messages: Membrane

216778:DX03 RS15200
gene id: 216778:DX03_RS15200
uniprot id: A0A023Y6L0
names: Function
names: Similarity
messages: Belongs to the DUF177 domain family.
messages: Plays a role in synthesis, processing and/or stability of 23S rRNA.

216778:DX03 RS02475
gene id: 216778:DX03_RS02475
uniprot id: A0A023XZW4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family. OpgH subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs).
messages: Membrane

216778:DX03 RS07810
gene id: 216778:DX03_RS07810
uniprot id: A0A023Y2U7
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

216778:DX03 RS02160
gene id: 216778:DX03_RS02160
uniprot id: A0A023XYP7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SUA5 family. TsaC subfamily.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Catalyzes the conversion of L-threonine, HCO(3)(-)/CO(2) and ATP to give threonylcarbamoyl-AMP (TC-AMP) as the acyladenylate intermediate, with the release of diphosphate.

216778:DX03 RS20465
gene id: 216778:DX03_RS20465
uniprot id: A0A023Y6T3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

216778:DX03 RS16545
gene id: 216778:DX03_RS16545
uniprot id: A0A023Y6M0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

216778:DX03 RS11085
gene id: 216778:DX03_RS11085
uniprot id: A0A023Y4G8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
messages: Cell membrane
messages: Monomer.

216778:DX03 RS11510
gene id: 216778:DX03_RS11510
uniprot id: A0A023Y432
names: Similarity
messages: Belongs to the GST superfamily.

216778:DX03 RS13155
gene id: 216778:DX03_RS13155
uniprot id: A0A4U3GSR5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase T family.
messages: Binds two Mg(2+) per subunit. The active form of the enzyme binds two Mg(2+) ions in its active site. The first Mg(2+) forms only one salt bridge with the protein.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.
messages: Trims short 3' overhangs of a variety of RNA species, leaving a one or two nucleotide 3' overhang. Responsible for the end-turnover of tRNA: specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis.

216778:DX03 RS16145
gene id: 216778:DX03_RS16145
uniprot id: A0A023Y6F2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

216778:DX03 RS15770
gene id: 216778:DX03_RS15770
uniprot id: A0A023Y692
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

216778:DX03 RS03745
gene id: 216778:DX03_RS03745
uniprot id: A0A023XZR0
names: Function
names: Similarity
messages: Belongs to the MurCDEF family. Mpl subfamily.
messages: Reutilizes the intact tripeptide L-alanyl-gamma-D-glutamyl-meso-diaminopimelate by linking it to UDP-N-acetylmuramate.

216778:DX03 RS19915
gene id: 216778:DX03_RS19915
uniprot id: A0A023Y9B5
names: Subcellular Location Annotation
messages: Membrane

216778:DX03 RS09715
gene id: 216778:DX03_RS09715
uniprot id: A0A023Y349
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the xylose isomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.

216778:DX03 RS09260
gene id: 216778:DX03_RS09260
uniprot id: A0A023Y3F6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DoxX family.
messages: Membrane

216778:DX03 RS10085
gene id: 216778:DX03_RS10085
uniprot id: A0A023Y366
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HflD family.
messages: Cell membrane
messages: Cytoplasm

216778:DX03 RS19015
gene id: 216778:DX03_RS19015
uniprot id: A0A023Y8Z4
names: Cofactor
names: Function
messages: Accepts electrons from ETF and reduces ubiquinone.
messages: Binds 1 [4Fe-4S] cluster.

216778:DX03 RS15785
gene id: 216778:DX03_RS15785
uniprot id: A0A4U3GES0
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

216778:DX03 RS07805
gene id: 216778:DX03_RS07805
uniprot id: A0A023Y252
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

216778:DX03 RS12965
gene id: 216778:DX03_RS12965
uniprot id: A0A023Y5J5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

216778:DX03 RS00300
gene id: 216778:DX03_RS00300
uniprot id: A0A023XY87
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0702 family.
messages: Cell membrane
messages: Membrane

216778:DX03 RS12060
gene id: 216778:DX03_RS12060
uniprot id: A0A023Y4F8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial glucokinase family.
messages: Cytoplasm

216778:DX03 RS07470
gene id: 216778:DX03_RS07470
uniprot id: A0A023Y2B0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

216778:DX03 RS11950
gene id: 216778:DX03_RS11950
uniprot id: A0A023Y4Q7
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the gamma-glutamyltransferase family.
messages: Cleaved by autocatalysis into a large and a small subunit.
messages: This enzyme consists of two polypeptide chains, which are synthesized in precursor form from a single polypeptide.

216778:DX03 RS16970
gene id: 216778:DX03_RS16970
uniprot id: A0A023Y7P1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MlaE permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the ABC transporter complex MlaFEDB, which is involved in a phospholipid transport pathway that maintains lipid asymmetry in the outer membrane by retrograde trafficking of phospholipids from the outer membrane to the inner membrane. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (MlaF), two transmembrane proteins (MlaE), two cytoplasmic solute-binding proteins (MlaB) and six periplasmic solute-binding proteins (MlaD).

216778:DX03 RS16950
gene id: 216778:DX03_RS16950
uniprot id: A0A023Y7F0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.
messages: Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.
messages: Cytoplasm
messages: Homodimer.

216778:DX03 RS03600
gene id: 216778:DX03_RS03600
uniprot id: A0A023XZN9
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

216778:DX03 RS02550
gene id: 216778:DX03_RS02550
uniprot id: A0A023XZX7
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

216778:DX03 RS06200
gene id: 216778:DX03_RS06200
uniprot id: A0A023Y1V0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the complex I 75 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: Composed of 13 different subunits. Subunits NuoCD, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

216778:DX03 RS17255
gene id: 216778:DX03_RS17255
uniprot id: A0A023Y718
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thioester dehydratase family. FabA subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)-decenoyl-ACP. Can catalyze the dehydratase reaction for beta-hydroxyacyl-ACPs with saturated chain lengths up to 16:0, being most active on intermediate chain length.

216778:DX03 RS15160
gene id: 216778:DX03_RS15160
uniprot id: A0A023Y6X8
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

216778:DX03 RS01480
gene id: 216778:DX03_RS01480
uniprot id: A0A023XY96
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HesB/IscA family.
messages: Binds 1 iron-sulfur cluster per subunit.
messages: Homodimer.
messages: Required for insertion of 4Fe-4S clusters for at least IspG.

216778:DX03 RS03735
gene id: 216778:DX03_RS03735
uniprot id: A0A023Y051
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphofructokinase type A (PFKA) family. PPi-dependent PFK group II subfamily. Clade 'B2' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions.
messages: Cytoplasm
messages: Homodimer.
messages: Non-allosteric.

216778:DX03 RS06760
gene id: 216778:DX03_RS06760
uniprot id: A0A023Y218
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0161 family.
messages: Cell membrane
messages: Could be involved in insertion of integral membrane proteins into the membrane.

216778:DX03 RS13270
gene id: 216778:DX03_RS13270
uniprot id: A0A023Y4V6
names: Similarity
messages: Belongs to the asparagine synthetase family.

216778:DX03 RS19910
gene id: 216778:DX03_RS19910
uniprot id: A0A023Y9I1
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

216778:DX03 RS20170
gene id: 216778:DX03_RS20170
uniprot id: A0A023Y8P6
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit contributes ATPase, 3'-5' helicase, exonuclease activity and loads RecA onto ssDNA.
messages: Belongs to the helicase family. UvrD subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotrimer of RecB, RecC and RecD. All subunits contribute to DNA-binding. Interacts with RecA.
messages: The C-terminal domain has nuclease activity and interacts with RecD. It interacts with RecA, facilitating its loading onto ssDNA.
messages: The N-terminal DNA-binding domain is a ssDNA-dependent ATPase and has ATP-dependent 3'-5' helicase function. This domain interacts with RecC.

216778:DX03 RS16585
gene id: 216778:DX03_RS16585
uniprot id: A0A023Y7G8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

216778:DX03 RS05145
gene id: 216778:DX03_RS05145
uniprot id: A0A023Y105
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

216778:DX03 RS17880
gene id: 216778:DX03_RS17880
uniprot id: A0A023Y7I4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

216778:DX03 RS12450
gene id: 216778:DX03_RS12450
uniprot id: A0A023Y592
names: Similarity
messages: To bacterial alkanal monooxygenase alpha and beta chains.

216778:DX03 RS19550
gene id: 216778:DX03_RS19550
uniprot id: A0A023Y8U5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RdgC family.
messages: May be involved in recombination.
messages: nucleoid

216778:DX03 RS06265
gene id: 216778:DX03_RS06265
uniprot id: A0A023Y1S7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

216778:DX03 RS16465
gene id: 216778:DX03_RS16465
uniprot id: A0A023Y754
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. SDR39U1 subfamily.

216778:DX03 RS12280
gene id: 216778:DX03_RS12280
uniprot id: A0A023Y4B6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

216778:DX03 RS12305
gene id: 216778:DX03_RS12305
uniprot id: A0A023Y4C4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Hfq family.
messages: Homohexamer.
messages: RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs.

216778:DX03 RS09340
gene id: 216778:DX03_RS09340
uniprot id: A0A023Y378
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

216778:DX03 RS09870
gene id: 216778:DX03_RS09870
uniprot id: A0A023Y3X8
names: Subcellular Location Annotation
messages: Membrane

216778:DX03 RS11545
gene id: 216778:DX03_RS11545
uniprot id: A0A023Y4Q0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

216778:DX03 RS18195
gene id: 216778:DX03_RS18195
uniprot id: A0A023Y7M1
names: Subcellular Location Annotation
messages: Membrane

216778:DX03 RS18150
gene id: 216778:DX03_RS18150
uniprot id: A0A023Y7U2
names: Similarity
messages: Belongs to the UPF0758 family.

216778:DX03 RS11700
gene id: 216778:DX03_RS11700
uniprot id: A0A023Y4K8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamE family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

216778:DX03 RS16115
gene id: 216778:DX03_RS16115
uniprot id: A0A023Y6Y6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

216778:DX03 RS10140
gene id: 216778:DX03_RS10140
uniprot id: A0A023Y3G5
names: Function
names: Similarity
messages: Belongs to the FlgM family.
messages: Responsible for the coupling of flagellin expression to flagellar assembly by preventing expression of the flagellin genes when a component of the middle class of proteins is defective. It negatively regulates flagellar genes by inhibiting the activity of FliA by directly binding to FliA.

216778:DX03 RS10330
gene id: 216778:DX03_RS10330
uniprot id: A0A023Y3W3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliP/MopC/SpaP family.
messages: Cell membrane
messages: Membrane
messages: Plays a role in the flagellum-specific transport system.

216778:DX03 RS10315
gene id: 216778:DX03_RS10315
uniprot id: A0A023Y3J2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliM family.
messages: Cell inner membrane
messages: FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
messages: Membrane

216778:DX03 RS00490
gene id: 216778:DX03_RS00490
uniprot id: A0A023XYQ7
names: Subcellular Location Annotation
messages: Membrane

216778:DX03 RS17390
gene id: 216778:DX03_RS17390
uniprot id: A0A023Y833
names: Similarity
messages: Belongs to the peptidase M13 family.

216778:DX03 RS13595
gene id: 216778:DX03_RS13595
uniprot id: A0A023Y587
names: Similarity
messages: Belongs to the bacterial ribosomal protein bTHX family.

216778:DX03 RS20155
gene id: 216778:DX03_RS20155
uniprot id: A0A023Y9N4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MlaE permease family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the ABC transporter complex MlaFEDB, which is involved in a phospholipid transport pathway that maintains lipid asymmetry in the outer membrane by retrograde trafficking of phospholipids from the outer membrane to the inner membrane. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (MlaF), two transmembrane proteins (MlaE), two cytoplasmic solute-binding proteins (MlaB) and six periplasmic solute-binding proteins (MlaD).

216778:DX03 RS18695
gene id: 216778:DX03_RS18695
uniprot id: A0A023Y8N9
names: Similarity
messages: Belongs to the NAPRTase family.

216778:DX03 RS05210
gene id: 216778:DX03_RS05210
uniprot id: A0A023Y1E6
names: Function
names: Similarity
messages: Belongs to the protease inhibitor I39 (alpha-2-macroglobulin) family. Bacterial alpha-2-macroglobulin subfamily.
messages: Protects the bacterial cell from host peptidases.

216778:DX03 RS15935
gene id: 216778:DX03_RS15935
uniprot id: A0A023Y6V7
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

216778:DX03 RS07245
gene id: 216778:DX03_RS07245
uniprot id: A0A023Y1S8
names: Subcellular Location Annotation
messages: Cytoplasm

216778:DX03 RS14025
gene id: 216778:DX03_RS14025
uniprot id: A0A023Y5U4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

216778:DX03 RS00320
gene id: 216778:DX03_RS00320
uniprot id: A0A023XYK2
names: Similarity
messages: Belongs to the Nudix hydrolase family.

216778:DX03 RS11390
gene id: 216778:DX03_RS11390
uniprot id: A0A023Y4Q9
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

216778:DX03 RS11260
gene id: 216778:DX03_RS11260
uniprot id: A0A023Y3Y8
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

216778:DX03 RS11585
gene id: 216778:DX03_RS11585
uniprot id: A0A023Y447
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Cell membrane
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

216778:DX03 RS17840
gene id: 216778:DX03_RS17840
uniprot id: A0A023Y8G6
names: Subcellular Location Annotation
messages: Membrane

216778:DX03 RS14300
gene id: 216778:DX03_RS14300
uniprot id: A0A023Y682
names: Similarity
messages: Belongs to the FPG family.

216778:DX03 RS06010
gene id: 216778:DX03_RS06010
uniprot id: A0A023Y0T7
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family. GreB subfamily.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length.

216778:DX03 RS07450
gene id: 216778:DX03_RS07450
uniprot id: A0A023Y1R1
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

216778:DX03 RS16850
gene id: 216778:DX03_RS16850
uniprot id: A0A023Y6T0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: ATPase component of the type II secretion system required for the energy-dependent secretion of extracellular factors such as proteases and toxins from the periplasm. Acts as a molecular motor to provide the energy that is required for assembly of the pseudopilus and the extrusion of substrates generated in the cytoplasm.
messages: Belongs to the GSP E family.
messages: Cell inner membrane

216778:DX03 RS05770
gene id: 216778:DX03_RS05770
uniprot id: A0A023Y1J7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

216778:DX03 RS19740
gene id: 216778:DX03_RS19740
uniprot id: A0A023Y978
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

216778:DX03 RS13475
gene id: 216778:DX03_RS13475
uniprot id: A0A023Y5Y1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

216778:DX03 RS12005
gene id: 216778:DX03_RS12005
uniprot id: A0A023Y448
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. Lipoprotein translocase (TC 3.A.1.125) family.
messages: Cell inner membrane
messages: Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner.
messages: The complex is composed of two ATP-binding proteins (LolD) and two transmembrane proteins (LolC and LolE).

216778:DX03 RS06395
gene id: 216778:DX03_RS06395
uniprot id: A0A023Y1V1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

216778:DX03 RS04465
gene id: 216778:DX03_RS04465
uniprot id: A0A023Y0K2
names: Similarity
messages: Belongs to the TPP enzyme family.

216778:DX03 RS13440
gene id: 216778:DX03_RS13440
uniprot id: A0A023Y4Y8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HemJ family.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.
messages: Catalyzes the oxidation of protoporphyrinogen IX to protoporphyrin IX.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

216778:DX03 RS00015
gene id: 216778:DX03_RS00015
uniprot id: A0A023XYI1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferrochelatase family.
messages: Catalyzes the ferrous insertion into protoporphyrin IX.
messages: Cytoplasm

216778:DX03 RS07420
gene id: 216778:DX03_RS07420
uniprot id: A0A4U3GR16
names: Caution
names: Subcellular Location Annotation
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

216778:DX03 RS04375
gene id: 216778:DX03_RS04375
uniprot id: A0A023Y052
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

216778:DX03 RS03160
gene id: 216778:DX03_RS03160
uniprot id: A0A023Y046
names: Subcellular Location Annotation
messages: Membrane

216778:DX03 RS20130
gene id: 216778:DX03_RS20130
uniprot id: A0A023Y9M5
names: Similarity
messages: Belongs to the glutathione peroxidase family.

216778:DX03 RS19675
gene id: 216778:DX03_RS19675
uniprot id: A0A023Y8W8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

216778:DX03 RS01590
gene id: 216778:DX03_RS01590
uniprot id: A0A023XZA5
names: Subcellular Location Annotation
messages: Membrane

216778:DX03 RS10040
gene id: 216778:DX03_RS10040
uniprot id: A0A023Y3D9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L/F-transferase family.
messages: Cytoplasm
messages: Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.

216778:DX03 RS13140
gene id: 216778:DX03_RS13140
uniprot id: A0A023Y5S6
names: Similarity
messages: Belongs to the UPF0276 family.

216778:DX03 RS03810
gene id: 216778:DX03_RS03810
uniprot id: A0A4V6X941
names: Caution
names: Function
names: Subcellular Location Annotation
messages: Periplasm
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.
messages: Transfers electrons from cytochrome c551 to cytochrome oxidase.

216778:DX03 RS13040
gene id: 216778:DX03_RS13040
uniprot id: A0A023Y5Q9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RlmKL family.
messages: Cytoplasm
messages: Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA.

216778:DX03 RS10285
gene id: 216778:DX03_RS10285
uniprot id: A0A023Y397
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliG family.
messages: Cell inner membrane
messages: FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
messages: Membrane

216778:DX03 RS03205
gene id: 216778:DX03_RS03205
uniprot id: A0A023Y086
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the carboxylate-amine ligase family. Glutamate--cysteine ligase type 2 subfamily.
messages: Belongs to the glutamate--cysteine ligase type 2 family. EgtA subfamily.
messages: Catalyzes the synthesis of gamma-glutamylcysteine (gamma-GC).
messages: Homodimer or monomer when oxidized or reduced, respectively.
messages: chloroplast

216778:DX03 RS15995
gene id: 216778:DX03_RS15995
uniprot id: A0A023Y6C5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the polyphosphate kinase 2 (PPK2) family. Class I subfamily.
messages: Homotetramer.
messages: Uses inorganic polyphosphate (polyP) as a donor to convert GDP to GTP or ADP to ATP.

216778:DX03 RS13390
gene id: 216778:DX03_RS13390
uniprot id: A0A023Y4X9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
messages: Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
messages: Homotrimer.

216778:DX03 RS03615
gene id: 216778:DX03_RS03615
uniprot id: A0A023Y029
names: Subcellular Location Annotation
messages: Membrane

216778:DX03 RS11065
gene id: 216778:DX03_RS11065
uniprot id: A0A023Y486
names: Similarity
names: Subunit
messages: Belongs to the aldehyde dehydrogenase family.
messages: Homotetramer.

216778:DX03 RS15245
gene id: 216778:DX03_RS15245
uniprot id: A0A023Y6V8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

216778:DX03 RS12025
gene id: 216778:DX03_RS12025
uniprot id: A0A023Y4S4
names: Cofactor
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Binds 1 [3Fe-4S] cluster.
messages: Binds 1 [4Fe-4S] cluster.

216778:DX03 RS17230
gene id: 216778:DX03_RS17230
uniprot id: A0A023Y711
names: Function
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family.
messages: Specifically catalyzes the dephosphorylation of 2-phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress.

216778:DX03 RS16215
gene id: 216778:DX03_RS16215
uniprot id: A0A023Y704
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptD family.
messages: Cell outer membrane
messages: Component of the lipopolysaccharide transport and assembly complex. Interacts with LptE and LptA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane.

216778:DX03 RS02310
gene id: 216778:DX03_RS02310
uniprot id: A0A023XZF7
names: Similarity
messages: Belongs to the OsmC/Ohr family.

216778:DX03 RS01320
gene id: 216778:DX03_RS01320
uniprot id: A0A023XYD4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

216778:DX03 RS15145
gene id: 216778:DX03_RS15145
uniprot id: A0A023Y6I0
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

216778:DX03 RS04640
gene id: 216778:DX03_RS04640
uniprot id: A0A023Y0A4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Pal lipoprotein family.
messages: Cell outer membrane
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

216778:DX03 RS18645
gene id: 216778:DX03_RS18645
uniprot id: A0A023Y8N1
names: Similarity
messages: Belongs to the CFA/CMAS family.

216778:DX03 RS12315
gene id: 216778:DX03_RS12315
uniprot id: A0A023Y5A3
names: Function
names: Similarity
messages: Belongs to the DHPS family.
messages: Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives.

216778:DX03 RS10835
gene id: 216778:DX03_RS10835
uniprot id: A0A023Y3H5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.

216778:DX03 RS09925
gene id: 216778:DX03_RS09925
uniprot id: A0A023Y3V0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

216778:DX03 RS10275
gene id: 216778:DX03_RS10275
uniprot id: A0A023Y433
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliE family.

216778:DX03 RS17460
gene id: 216778:DX03_RS17460
uniprot id: A0A023Y7E8
names: Similarity
messages: Belongs to the transglycosylase Slt family.

216778:DX03 RS12790
gene id: 216778:DX03_RS12790
uniprot id: A0A023Y594
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell inner membrane
messages: Membrane

216778:DX03 RS15645
gene id: 216778:DX03_RS15645
uniprot id: A0A023Y6F7
names: Function
names: Similarity
messages: Belongs to the LDH/MDH superfamily. MDH type 2 family.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.

216778:DX03 RS05440
gene id: 216778:DX03_RS05440
uniprot id: A0A023Y1H9
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

216778:DX03 RS17250
gene id: 216778:DX03_RS17250
uniprot id: A0A023Y7L2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

216778:DX03 RS17685
gene id: 216778:DX03_RS17685
uniprot id: A0A023Y7J9
names: Function
messages: Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).

216778:DX03 RS15810
gene id: 216778:DX03_RS15810
uniprot id: A0A023Y734
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

216778:DX03 RS12920
gene id: 216778:DX03_RS12920
uniprot id: A0A023Y4Q8
names: Similarity
messages: Belongs to the glutamine synthetase family.

216778:DX03 RS07205
gene id: 216778:DX03_RS07205
uniprot id: A0A023Y2B4
names: Subunit
messages: Interacts transiently with the RNA polymerase catalytic core formed by RpoA, RpoB, RpoC and RpoZ (2 alpha, 1 beta, 1 beta' and 1 omega subunit) to form the RNA polymerase holoenzyme that can initiate transcription.

216778:DX03 RS20085
gene id: 216778:DX03_RS20085
uniprot id: A0A023Y960
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

216778:DX03 RS09460
gene id: 216778:DX03_RS09460
uniprot id: A0A023Y3K2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIIB subfamily.
messages: Cell inner membrane
messages: Mediates magnesium influx to the cytosol.
messages: Membrane

216778:DX03 RS18680
gene id: 216778:DX03_RS18680
uniprot id: A0A023Y7U4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nicotinamide ribonucleoside (NR) uptake permease (TC 4.B.1) family.
messages: Membrane
messages: Required for nicotinamide riboside transport across the inner membrane.

216778:DX03 RS12030
gene id: 216778:DX03_RS12030
uniprot id: A0A023Y455
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
messages: Cell inner membrane
messages: Membrane

216778:DX03 RS20230
gene id: 216778:DX03_RS20230
uniprot id: A0A023Y8Z6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

216778:DX03 RS10165
gene id: 216778:DX03_RS10165
uniprot id: A0A023Y3G9
names: Function
names: Similarity
messages: Belongs to the FlgD family.
messages: Required for flagellar hook formation. May act as a scaffolding protein.

216778:DX03 RS10200
gene id: 216778:DX03_RS10200
uniprot id: A0A023Y425
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the flagella basal body rod proteins family.
messages: Secreted

216778:DX03 RS07260
gene id: 216778:DX03_RS07260
uniprot id: A0A4U3GS78
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

216778:DX03 RS16905
gene id: 216778:DX03_RS16905
uniprot id: A0A023Y6U0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M17 family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm
messages: Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.

216778:DX03 RS02280
gene id: 216778:DX03_RS02280
uniprot id: A0A023XZP1
names: Subunit
messages: Interacts transiently with the RNA polymerase catalytic core formed by RpoA, RpoB, RpoC and RpoZ (2 alpha, 1 beta, 1 beta' and 1 omega subunit) to form the RNA polymerase holoenzyme that can initiate transcription.

216778:DX03 RS04410
gene id: 216778:DX03_RS04410
uniprot id: A0A023Y0T3
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

216778:DX03 RS12385
gene id: 216778:DX03_RS12385
uniprot id: A0A023Y4M0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsB family.
messages: Cell inner membrane
messages: Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.
messages: Part of a complex composed of FtsB, FtsL and FtsQ.

216778:DX03 RS06110
gene id: 216778:DX03_RS06110
uniprot id: A0A023Y0V3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

216778:DX03 RS07545
gene id: 216778:DX03_RS07545
uniprot id: A0A023Y2C3
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with bS18 to 16S ribosomal RNA.

216778:DX03 RS07190
gene id: 216778:DX03_RS07190
uniprot id: A0A023Y1I8
names: Similarity
messages: Belongs to the ferredoxin--NADP reductase type 1 family.

216778:DX03 RS04345
gene id: 216778:DX03_RS04345
uniprot id: A0A023XZW1
names: Similarity
messages: Belongs to the N-Me-Phe pilin family.

216778:DX03 RS12380
gene id: 216778:DX03_RS12380
uniprot id: A0A023Y4E3
names: Function
names: Similarity
messages: Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).

216778:DX03 RS02740
gene id: 216778:DX03_RS02740
uniprot id: A0A023XZ15
names: Similarity
messages: Belongs to the UPF0234 family.

216778:DX03 RS05745
gene id: 216778:DX03_RS05745
uniprot id: A0A023Y1J1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm

216778:DX03 RS06075
gene id: 216778:DX03_RS06075
uniprot id: A0A023Y1P8
names: Similarity
messages: Belongs to the TrpF family.

216778:DX03 RS01440
gene id: 216778:DX03_RS01440
uniprot id: A0A023XZ75
names: Function
names: Similarity
messages: Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage.
messages: Belongs to the Nudix hydrolase family. RppH subfamily.

216778:DX03 RS07575
gene id: 216778:DX03_RS07575
uniprot id: A0A023Y2C5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ZipA family.
messages: Cell inner membrane
messages: Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins.
messages: Interacts with FtsZ via their C-terminal domains.

216778:DX03 RS03620
gene id: 216778:DX03_RS03620
uniprot id: A0A023XZG5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ThiC family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
messages: Homodimer.

216778:DX03 RS00360
gene id: 216778:DX03_RS00360
uniprot id: A0A023XXX4
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

216778:DX03 RS04310
gene id: 216778:DX03_RS04310
uniprot id: A0A023Y0R2
names: Cofactor
names: Similarity
messages: Belongs to the RimK family.
messages: Binds 2 magnesium or manganese ions per subunit.

216778:DX03 RS10755
gene id: 216778:DX03_RS10755
uniprot id: A0A023Y423
names: Similarity
messages: Belongs to the N-acylglucosamine 2-epimerase family.

216778:DX03 RS16965
gene id: 216778:DX03_RS16965
uniprot id: A0A023Y7T7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThrE exporter (TC 2.A.79) family.
messages: Membrane

216778:DX03 RS12070
gene id: 216778:DX03_RS12070
uniprot id: A0A023Y515
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Catalyzes the dehydration of 6-phospho-D-gluconate to 2-dehydro-3-deoxy-6-phospho-D-gluconate.

216778:DX03 RS14930
gene id: 216778:DX03_RS14930
uniprot id: A0A023Y6R2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

216778:DX03 RS15375
gene id: 216778:DX03_RS15375
uniprot id: A0A023Y6X0
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

216778:DX03 RS09980
gene id: 216778:DX03_RS09980
uniprot id: A0A023Y3M9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

216778:DX03 RS06685
gene id: 216778:DX03_RS06685
uniprot id: A0A023Y1R7
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Membrane

216778:DX03 RS16570
gene id: 216778:DX03_RS16570
uniprot id: A0A023Y6M4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MraZ family.
messages: Forms oligomers.
messages: nucleoid

216778:DX03 RS16005
gene id: 216778:DX03_RS16005
uniprot id: A0A023Y7A5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0761 family.
messages: Cell membrane
messages: Membrane

216778:DX03 RS08590
gene id: 216778:DX03_RS08590
uniprot id: A0A023Y2H3
names: Subcellular Location Annotation
messages: Membrane

216778:DX03 RS19955
gene id: 216778:DX03_RS19955
uniprot id: A0A023Y8J7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

216778:DX03 RS15655
gene id: 216778:DX03_RS15655
uniprot id: A0A023Y710
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

216778:DX03 RS19515
gene id: 216778:DX03_RS19515
uniprot id: A0A023Y996
names: Similarity
messages: Belongs to the type IB topoisomerase family.

216778:DX03 RS02585
gene id: 216778:DX03_RS02585
uniprot id: A0A023XZK6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family. T3SS ATPase subfamily.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has four main subunits: a(1), b(1), b'(1) and c(9-12).
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

216778:DX03 RS10735
gene id: 216778:DX03_RS10735
uniprot id: A0A023Y3F8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acireductone dioxygenase (ARD) family.
messages: Binds 1 Fe(2+) cation per monomer.
messages: Binds 1 nickel ion per monomer.
messages: Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4-methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway.
messages: Monomer.

216778:DX03 RS14830
gene id: 216778:DX03_RS14830
uniprot id: A0A023Y6N8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

216778:DX03 RS11890
gene id: 216778:DX03_RS11890
uniprot id: A0A023Y516
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

216778:DX03 RS15850
gene id: 216778:DX03_RS15850
uniprot id: A0A023Y6I8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

216778:DX03 RS13120
gene id: 216778:DX03_RS13120
uniprot id: A0A023Y5M2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Membrane

216778:DX03 RS17160
gene id: 216778:DX03_RS17160
uniprot id: A0A023Y779
names: Cofactor
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.
messages: Binds 1 zinc ion per subunit.

216778:DX03 RS05810
gene id: 216778:DX03_RS05810
uniprot id: A0A023Y0Q0
names: Similarity
messages: Belongs to the peptidase U62 family.

216778:DX03 RS10415
gene id: 216778:DX03_RS10415
uniprot id: A0A023Y3K5
names: Similarity
messages: Belongs to the MotB family.

216778:DX03 RS02185
gene id: 216778:DX03_RS02185
uniprot id: A0A023XYQ3
names: Similarity
messages: Belongs to the DprA/Smf family.

216778:DX03 RS11465
gene id: 216778:DX03_RS11465
uniprot id: A0A023Y4S3
names: Similarity
messages: Belongs to the intradiol ring-cleavage dioxygenase family.

216778:DX03 RS00125
gene id: 216778:DX03_RS00125
uniprot id: A0A023XY61
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

216778:DX03 RS10860
gene id: 216778:DX03_RS10860
uniprot id: A0A023Y3I0
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Homodimer.

216778:DX03 RS16485
gene id: 216778:DX03_RS16485
uniprot id: A0A023Y7F1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

216778:DX03 RS07340
gene id: 216778:DX03_RS07340
uniprot id: A0A023Y262
names: Function
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
messages: Catalyzes two reactions in de novo purine nucleotide biosynthesis. Catalyzes the breakdown of 5-aminoimidazole- (N-succinylocarboxamide) ribotide (SAICAR or 2-[5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamido]succinate) to 5-aminoimidazole-4-carboxamide ribotide (AICAR or 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide) and fumarate, and of adenylosuccinate (ADS or N(6)-(1,2-dicarboxyethyl)-AMP) to adenosine monophosphate (AMP) and fumarate.

216778:DX03 RS11235
gene id: 216778:DX03_RS11235
uniprot id: A0A023Y3Y3
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

216778:DX03 RS11985
gene id: 216778:DX03_RS11985
uniprot id: A0A023Y4E0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. SRP is a ribonucleoprotein composed of Ffh and a 4.5S RNA molecule.

216778:DX03 RS13930
gene id: 216778:DX03_RS13930
uniprot id: A0A023Y5E5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lactate permease family.
messages: Cell inner membrane
messages: Membrane
messages: Uptake of L-lactate across the membrane. Can also transport D-lactate and glycolate.

216778:DX03 RS01290
gene id: 216778:DX03_RS01290
uniprot id: A0A023XY63
names: Subcellular Location Annotation
messages: Membrane

216778:DX03 RS02050
gene id: 216778:DX03_RS02050
uniprot id: A0A023XZI7
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

216778:DX03 RS12775
gene id: 216778:DX03_RS12775
uniprot id: A0A023Y4W2
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Rieske iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.
messages: Membrane
messages: The Rieske protein is a high potential 2Fe-2S protein.
messages: The main subunits of complex b-c1 are: cytochrome b, cytochrome c1 and the Rieske protein.

216778:DX03 RS14925
gene id: 216778:DX03_RS14925
uniprot id: A0A023Y612
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

216778:DX03 RS06825
gene id: 216778:DX03_RS06825
uniprot id: A0A023Y191
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm
messages: In the N-terminal section; belongs to the lyase 1 family. Argininosuccinate lyase subfamily.

216778:DX03 RS07055
gene id: 216778:DX03_RS07055
uniprot id: A0A023Y1F4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

216778:DX03 RS04605
gene id: 216778:DX03_RS04605
uniprot id: A0A023Y0N5
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvB family.
messages: Cytoplasm
messages: Has 3 domains, the large (RuvB-L) and small ATPase (RuvB-S) domains and the C-terminal head (RuvB-H) domain. The head domain binds DNA, while the ATPase domains jointly bind ATP, ADP or are empty depending on the state of the subunit in the translocation cycle. During a single DNA translocation step the structure of each domain remains the same, but their relative positions change.
messages: Homohexamer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time. Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange. Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration. The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration. Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.

216778:DX03 RS04890
gene id: 216778:DX03_RS04890
uniprot id: A0A023Y159
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvT family.
messages: The glycine cleavage system catalyzes the degradation of glycine.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

216778:DX03 RS01530
gene id: 216778:DX03_RS01530
uniprot id: A0A023XYA5
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

216778:DX03 RS12975
gene id: 216778:DX03_RS12975
uniprot id: A0A023Y4R5
names: Subcellular Location Annotation
messages: Membrane

216778:DX03 RS17305
gene id: 216778:DX03_RS17305
uniprot id: A0A023Y730
names: Function
names: Similarity
messages: Belongs to the DadA oxidoreductase family.
messages: Oxidative deamination of D-amino acids.

216778:DX03 RS01230
gene id: 216778:DX03_RS01230
uniprot id: A0A023XZ14
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tryptophan 2,3-dioxygenase family.
messages: Binds 1 heme group per subunit.
messages: Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L-tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety.
messages: Homotetramer.

216778:DX03 RS19315
gene id: 216778:DX03_RS19315
uniprot id: A0A023Y951
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane
messages: Membrane

216778:DX03 RS17325
gene id: 216778:DX03_RS17325
uniprot id: A0A023Y7M8
names: Cofactor
names: Similarity
messages: Belongs to the MsrB Met sulfoxide reductase family.
messages: Binds 1 zinc ion per subunit. The zinc ion is important for the structural integrity of the protein.

216778:DX03 RS00470
gene id: 216778:DX03_RS00470
uniprot id: A0A023XYM8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Cell membrane
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

216778:DX03 RS06900
gene id: 216778:DX03_RS06900
uniprot id: A0A023Y248
names: Subcellular Location Annotation
messages: Membrane

216778:DX03 RS03405
gene id: 216778:DX03_RS03405
uniprot id: A0A023Y0B6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

216778:DX03 RS15725
gene id: 216778:DX03_RS15725
uniprot id: A0A023Y6G9
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

216778:DX03 RS11665
gene id: 216778:DX03_RS11665
uniprot id: A0A023Y4W4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

216778:DX03 RS02515
gene id: 216778:DX03_RS02515
uniprot id: A0A023XYY4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NlpA lipoprotein family.
messages: Membrane

216778:DX03 RS02165
gene id: 216778:DX03_RS02165
uniprot id: A0A023XYW6
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

216778:DX03 RS12095
gene id: 216778:DX03_RS12095
uniprot id: A0A023Y520
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

216778:DX03 RS06940
gene id: 216778:DX03_RS06940
uniprot id: A0A023Y2A0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AB hydrolase superfamily. MetX family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transfers a succinyl group from succinyl-CoA to L-serine, forming succinyl-L-serine.

216778:DX03 RS01255
gene id: 216778:DX03_RS01255
uniprot id: A0A023XZ17
names: Cofactor
names: Similarity
messages: Belongs to the 4HPPD family.
messages: Binds 1 Fe cation per subunit.

216778:DX03 RS14615
gene id: 216778:DX03_RS14615
uniprot id: A0A023Y5J7
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

216778:DX03 RS10075
gene id: 216778:DX03_RS10075
uniprot id: A0A023Y407
names: Similarity
names: Subunit
messages: Belongs to the Nudix hydrolase family. NudJ subfamily.
messages: Monomer.

216778:DX03 RS15940
gene id: 216778:DX03_RS15940
uniprot id: A0A023Y6B7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

216778:DX03 RS03710
gene id: 216778:DX03_RS03710
uniprot id: A0A023Y044
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ExbD/TolR family.
messages: Cell inner membrane
messages: Cell membrane
messages: Involved in the TonB-dependent energy-dependent transport of various receptor-bound substrates.
messages: Membrane
messages: The accessory proteins ExbB and ExbD seem to form a complex with TonB.

216778:DX03 RS03905
gene id: 216778:DX03_RS03905
uniprot id: A0A023Y0H6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase PH family.
messages: Homohexameric ring arranged as a trimer of dimers.
messages: Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.

216778:DX03 RS10935
gene id: 216778:DX03_RS10935
uniprot id: A0A023Y3J3
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

216778:DX03 RS18945
gene id: 216778:DX03_RS18945
uniprot id: A0A023Y8T3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

216778:DX03 RS13115
gene id: 216778:DX03_RS13115
uniprot id: A0A023Y5S2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

216778:DX03 RS15510
gene id: 216778:DX03_RS15510
uniprot id: A0A023Y6P9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LpxH family.
messages: Binds 2 Mn(2+) ions per subunit in a binuclear metal center.
messages: Cell inner membrane
messages: Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

216778:DX03 RS04165
gene id: 216778:DX03_RS04165
uniprot id: A0A023XZS2
names: Similarity
messages: Belongs to the class I fructose-bisphosphate aldolase family.

216778:DX03 RS15980
gene id: 216778:DX03_RS15980
uniprot id: A0A023Y7A2
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

216778:DX03 RS18625
gene id: 216778:DX03_RS18625
uniprot id: A0A023Y8C2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the calycin superfamily. Lipocalin family.
messages: Cell outer membrane
messages: Homodimer.
messages: Involved in the storage or transport of lipids necessary for membrane maintenance under stressful conditions. Displays a binding preference for lysophospholipids.

216778:DX03 RS02615
gene id: 216778:DX03_RS02615
uniprot id: A0A023XYZ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

216778:DX03 RS11675
gene id: 216778:DX03_RS11675
uniprot id: A0A023Y4K3
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

216778:DX03 RS15320
gene id: 216778:DX03_RS15320
uniprot id: A0A023Y6B5
names: Function
names: Subunit
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease.

216778:DX03 RS12425
gene id: 216778:DX03_RS12425
uniprot id: A0A023Y584
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
messages: Membrane

216778:DX03 RS01210
gene id: 216778:DX03_RS01210
uniprot id: A0A023XYP9
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

216778:DX03 RS17095
gene id: 216778:DX03_RS17095
uniprot id: A0A023Y7R8
names: Similarity
messages: Belongs to the ABC transporter superfamily.

216778:DX03 RS15490
gene id: 216778:DX03_RS15490
uniprot id: A0A023Y656
names: Similarity
messages: Belongs to the GppA/Ppx family.

216778:DX03 RS11250
gene id: 216778:DX03_RS11250
uniprot id: A0A023Y4C3
names: Similarity
messages: Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family.

216778:DX03 RS04035
gene id: 216778:DX03_RS04035
uniprot id: A0A023Y0B0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial secretin family. PilQ subfamily.
messages: Cell outer membrane
messages: Membrane

216778:DX03 RS02025
gene id: 216778:DX03_RS02025
uniprot id: A0A023XZI2
names: Function
names: Similarity
messages: Belongs to the class-I DAHP synthase family.
messages: Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP).

216778:DX03 RS15600
gene id: 216778:DX03_RS15600
uniprot id: A0A023Y747
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily.

216778:DX03 RS10160
gene id: 216778:DX03_RS10160
uniprot id: A0A023Y379
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

216778:DX03 RS01120
gene id: 216778:DX03_RS01120
uniprot id: A0A023XYA1
names: Function
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. SpeA subfamily.
messages: Catalyzes the biosynthesis of agmatine from arginine.

216778:DX03 RS04510
gene id: 216778:DX03_RS04510
uniprot id: A0A023Y0Z7
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

216778:DX03 RS10390
gene id: 216778:DX03_RS10390
uniprot id: A0A023Y3K3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sigma-70 factor family. FliA subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor controls the expression of flagella-related genes.

216778:DX03 RS08705
gene id: 216778:DX03_RS08705
uniprot id: A0A4U3GQM7
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

216778:DX03 RS01620
gene id: 216778:DX03_RS01620
uniprot id: A0A023XZ95
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

216778:DX03 RS04610
gene id: 216778:DX03_RS04610
uniprot id: A0A023Y027
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

216778:DX03 RS12810
gene id: 216778:DX03_RS12810
uniprot id: A0A023Y5H5
names: Subcellular Location Annotation
messages: Membrane

216778:DX03 RS17945
gene id: 216778:DX03_RS17945
uniprot id: A0A023Y8C5
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SURF1 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

216778:DX03 RS16155
gene id: 216778:DX03_RS16155
uniprot id: A0A023Y7D2
names: Function
names: Similarity
messages: Belongs to the transaldolase family. Type 1 subfamily.
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

216778:DX03 RS00395
gene id: 216778:DX03_RS00395
uniprot id: A0A023XYL6
names: Subunit
messages: Monomer.

216778:DX03 RS16205
gene id: 216778:DX03_RS16205
uniprot id: A0A023Y7E0
names: Similarity
messages: Belongs to the Cob(I)alamin adenosyltransferase family.

216778:DX03 RS16220
gene id: 216778:DX03_RS16220
uniprot id: A0A023Y6G6
names: Domain
names: Function
names: Subcellular Location Annotation
messages: Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation.
messages: Periplasm
messages: The PPIase activity resides only in the second parvulin domain. The N-terminal region and the C-terminal tail are necessary and sufficient for the chaperone activity of SurA. The PPIase activity is dispensable for SurA to function as a chaperone. The N-terminal region and the C-terminal tail are also required for porin recognition.

216778:DX03 RS15755
gene id: 216778:DX03_RS15755
uniprot id: A0A023Y771
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

216778:DX03 RS15700
gene id: 216778:DX03_RS15700
uniprot id: A0A023Y6G4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

216778:DX03 RS06830
gene id: 216778:DX03_RS06830
uniprot id: A0A023Y1I2
names: Similarity
messages: Belongs to the YciI family.

216778:DX03 RS17825
gene id: 216778:DX03_RS17825
uniprot id: A0A023Y818
names: Cofactor
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.

216778:DX03 RS13410
gene id: 216778:DX03_RS13410
uniprot id: A0A023Y5H9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

216778:DX03 RS17045
gene id: 216778:DX03_RS17045
uniprot id: A0A023Y7Q6
names: Cofactor
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.
messages: Binds 1 FAD per dimer.

216778:DX03 RS07510
gene id: 216778:DX03_RS07510
uniprot id: A0A023Y2P4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 3-HAO family.
messages: Binds 2 Fe(2+) ions per subunit.
messages: Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate.
messages: Homodimer.

216778:DX03 RS18670
gene id: 216778:DX03_RS18670
uniprot id: A0A023Y8N5
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

216778:DX03 RS12330
gene id: 216778:DX03_RS12330
uniprot id: A0A023Y4D0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.
messages: Cytoplasm
messages: Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.

216778:DX03 RS01910
gene id: 216778:DX03_RS01910
uniprot id: A0A023XYR4
names: Subcellular Location Annotation
messages: Membrane

216778:DX03 RS18895
gene id: 216778:DX03_RS18895
uniprot id: A0A023Y8S5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Membrane

216778:DX03 RS06190
gene id: 216778:DX03_RS06190
uniprot id: A0A023Y0W4
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

216778:DX03 RS16415
gene id: 216778:DX03_RS16415
uniprot id: A0A023Y746
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

216778:DX03 RS02890
gene id: 216778:DX03_RS02890
uniprot id: A0A023XZ37
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M1 family.
messages: Binds 1 zinc ion per subunit.

216778:DX03 RS00875
gene id: 216778:DX03_RS00875
uniprot id: A0A023XYU6
names: Similarity
messages: Belongs to the SIS family. AgaS subfamily.

216778:DX03 RS07325
gene id: 216778:DX03_RS07325
uniprot id: A0A023Y1U5
names: Function
names: Similarity
messages: Belongs to the alpha-ketoglutarate dehydrogenase family.
messages: E1 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the decarboxylation of 2-oxoglutarate, the first step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).

216778:DX03 RS15865
gene id: 216778:DX03_RS15865
uniprot id: A0A023Y6U8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

216778:DX03 RS00295
gene id: 216778:DX03_RS00295
uniprot id: A0A023XYJ8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
messages: Single-chain monomer with multiple functions.

216778:DX03 RS16895
gene id: 216778:DX03_RS16895
uniprot id: A0A023Y7M6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptF/LptG family.
messages: Component of the lipopolysaccharide transport and assembly complex. The LptBFG transporter is composed of two ATP-binding proteins (LptB) and two transmembrane proteins (LptF and LptG).
messages: Membrane
messages: Part of the ABC transporter complex LptBFG involved in the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane.

216778:DX03 RS01920
gene id: 216778:DX03_RS01920
uniprot id: A0A023XZG0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

216778:DX03 RS03065
gene id: 216778:DX03_RS03065
uniprot id: A0A023XZ70
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. FHS transporter (TC 2.A.1.7) family.
messages: Cell inner membrane
messages: Intake of glucose and galactose.
messages: Membrane

216778:DX03 RS03825
gene id: 216778:DX03_RS03825
uniprot id: A0A023Y0J5
names: Cofactor
names: Similarity
messages: Belongs to the rubredoxin family.
messages: Binds 1 Fe(3+) ion per subunit.

216778:DX03 RS03215
gene id: 216778:DX03_RS03215
uniprot id: A0A023XZU9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

216778:DX03 RS03675
gene id: 216778:DX03_RS03675
uniprot id: A0A023Y0G6
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

216778:DX03 RS01850
gene id: 216778:DX03_RS01850
uniprot id: A0A023XZ34
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

216778:DX03 RS02755
gene id: 216778:DX03_RS02755
uniprot id: A0A023XZX8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

216778:DX03 RS18455
gene id: 216778:DX03_RS18455
uniprot id: A0A023Y7Y7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EamA transporter family.
messages: Membrane

216778:DX03 RS16785
gene id: 216778:DX03_RS16785
uniprot id: A0A023Y7K8
names: Function
names: PTM
names: Similarity
messages: Belongs to the NAPRTase family.
messages: Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP.
messages: Transiently phosphorylated on a His residue during the reaction cycle. Phosphorylation strongly increases the affinity for substrates and increases the rate of nicotinate D-ribonucleotide production. Dephosphorylation regenerates the low-affinity form of the enzyme, leading to product release.

216778:DX03 RS05975
gene id: 216778:DX03_RS05975
uniprot id: A0A023Y1N0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.

216778:DX03 RS08530
gene id: 216778:DX03_RS08530
uniprot id: A0A023Y2R9
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

216778:DX03 RS06170
gene id: 216778:DX03_RS06170
uniprot id: A0A023Y139
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 3 family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

216778:DX03 RS13995
gene id: 216778:DX03_RS13995
uniprot id: A0A023Y622
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

216778:DX03 RS07390
gene id: 216778:DX03_RS07390
uniprot id: A0A023Y274
names: Similarity
messages: Belongs to the glutathione peroxidase family.

216778:DX03 RS11315
gene id: 216778:DX03_RS11315
uniprot id: A0A023Y4P3
names: Similarity
messages: Belongs to the polysaccharide synthase family.

216778:DX03 RS16355
gene id: 216778:DX03_RS16355
uniprot id: A0A023Y7G4
names: Activity Regulation
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.
messages: Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.
messages: Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate.

216778:DX03 RS14855
gene id: 216778:DX03_RS14855
uniprot id: A0A023Y6P5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptA family.
messages: Component of the lipopolysaccharide transport and assembly complex.
messages: Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm.
messages: Periplasm

216778:DX03 RS03330
gene id: 216778:DX03_RS03330
uniprot id: A0A023Y0A3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell outer membrane

216778:DX03 RS04825
gene id: 216778:DX03_RS04825
uniprot id: A0A023Y161
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

216778:DX03 RS04400
gene id: 216778:DX03_RS04400
uniprot id: A0A023Y058
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamD family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

216778:DX03 RS00805
gene id: 216778:DX03_RS00805
uniprot id: A0A023XYG7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AB hydrolase superfamily. Carboxylesterase BioH family.
messages: Cytoplasm
messages: Monomer.
messages: The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters.

216778:DX03 RS11805
gene id: 216778:DX03_RS11805
uniprot id: A0A023Y401
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell outer membrane

216778:DX03 RS02645
gene id: 216778:DX03_RS02645
uniprot id: A0A023XZ76
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

216778:DX03 RS15735
gene id: 216778:DX03_RS15735
uniprot id: A0A4U3GFR4
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.
messages: This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

216778:DX03 RS12785
gene id: 216778:DX03_RS12785
uniprot id: A0A023Y5H2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methylthiotransferase family. MiaB subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
messages: Cytoplasm
messages: Monomer.

216778:DX03 RS05290
gene id: 216778:DX03_RS05290
uniprot id: A0A023Y1F7
names: Function
names: Similarity
messages: Belongs to the catalase family. HPII subfamily.
messages: Serves to protect cells from the toxic effects of hydrogen peroxide.

216778:DX03 RS03115
gene id: 216778:DX03_RS03115
uniprot id: A0A023XZ77
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

216778:DX03 RS15250
gene id: 216778:DX03_RS15250
uniprot id: A0A023Y6L8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

216778:DX03 RS10595
gene id: 216778:DX03_RS10595
uniprot id: A0A023Y4C5
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

216778:DX03 RS12410
gene id: 216778:DX03_RS12410
uniprot id: A0A023Y4M7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family. ParE type 1 subfamily.
messages: Heterotetramer composed of ParC and ParE.
messages: Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.

216778:DX03 RS02565
gene id: 216778:DX03_RS02565
uniprot id: A0A023XYZ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase A chain family.
messages: Cell membrane
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

216778:DX03 RS15165
gene id: 216778:DX03_RS15165
uniprot id: A0A023Y6T6
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

216778:DX03 RS11325
gene id: 216778:DX03_RS11325
uniprot id: A0A023Y4D8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LapB family.
messages: Cell inner membrane
messages: Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane.

216778:DX03 RS15815
gene id: 216778:DX03_RS15815
uniprot id: A0A4U3GER2
names: Caution
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: Methylated by PrmB.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

216778:DX03 RS03875
gene id: 216778:DX03_RS03875
uniprot id: A0A023Y0K5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M24B family. Bacterial-type prolidase subfamily.
messages: Binds 2 manganese ions per subunit.
messages: Splits dipeptides with a prolyl residue in the C-terminal position.

216778:DX03 RS07440
gene id: 216778:DX03_RS07440
uniprot id: A0A023Y2I9
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

216778:DX03 RS07120
gene id: 216778:DX03_RS07120
uniprot id: A0A023Y1P9
names: Similarity
messages: Belongs to the barstar family.

216778:DX03 RS08245
gene id: 216778:DX03_RS08245
uniprot id: A0A023Y2B7
names: Function
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.
messages: Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate.

216778:DX03 RS14665
gene id: 216778:DX03_RS14665
uniprot id: A0A023Y5K7
names: Function
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.
messages: Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine.

216778:DX03 RS14595
gene id: 216778:DX03_RS14595
uniprot id: A0A023Y5U1
names: Function
names: Similarity
messages: Belongs to the MurL family.
messages: Cell wall formation. Catalyzes epimerization of the terminal L-glutamate in UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-L-glutamate.

216778:DX03 RS18880
gene id: 216778:DX03_RS18880
uniprot id: A0A023Y7X7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

216778:DX03 RS14030
gene id: 216778:DX03_RS14030
uniprot id: A0A023Y585
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

216778:DX03 RS03855
gene id: 216778:DX03_RS03855
uniprot id: A0A023Y0G7
names: Function
names: Similarity
names: Subunit
messages: Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division.
messages: Belongs to the ZapA family. Type 1 subfamily.
messages: Homodimer. Interacts with FtsZ.

216778:DX03 RS14605
gene id: 216778:DX03_RS14605
uniprot id: A0A023Y6E6
names: Similarity
messages: Belongs to the PhzF family.

216778:DX03 RS11060
gene id: 216778:DX03_RS11060
uniprot id: A0A023Y4G4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial sugar transferase family.
messages: Membrane

216778:DX03 RS02845
gene id: 216778:DX03_RS02845
uniprot id: A0A023XZA8
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

216778:DX03 RS16735
gene id: 216778:DX03_RS16735
uniprot id: A0A023Y7J6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AlgF family.
messages: Periplasm

216778:DX03 RS18215
gene id: 216778:DX03_RS18215
uniprot id: A0A023Y866
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

216778:DX03 RS07955
gene id: 216778:DX03_RS07955
uniprot id: A0A023Y1Z4
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

216778:DX03 RS20235
gene id: 216778:DX03_RS20235
uniprot id: A0A023Y9Q3
names: Similarity
messages: Belongs to the UPF0225 family.

216778:DX03 RS05065
gene id: 216778:DX03_RS05065
uniprot id: A0A023Y184
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

216778:DX03 RS16885
gene id: 216778:DX03_RS16885
uniprot id: A0A023Y715
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerD subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

216778:DX03 RS02820
gene id: 216778:DX03_RS02820
uniprot id: A0A023XZA4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

216778:DX03 RS06645
gene id: 216778:DX03_RS06645
uniprot id: A0A023Y1D7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm

216778:DX03 RS12530
gene id: 216778:DX03_RS12530
uniprot id: A0A023Y5B2
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Monomer.

216778:DX03 RS10750
gene id: 216778:DX03_RS10750
uniprot id: A0A023Y4A9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycosyl hydrolase 2 family.
messages: Exoglycosidase that cleaves the single beta-linked mannose residue from the non-reducing end of all N-linked glycoprotein oligosaccharides.
messages: Homodimer.
messages: Monomer.
messages: Secreted

216778:DX03 RS11595
gene id: 216778:DX03_RS11595
uniprot id: A0A023Y4R1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.

216778:DX03 RS12485
gene id: 216778:DX03_RS12485
uniprot id: A0A023Y4G6
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

216778:DX03 RS16160
gene id: 216778:DX03_RS16160
uniprot id: A0A023Y793
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

216778:DX03 RS06105
gene id: 216778:DX03_RS06105
uniprot id: A0A023Y1F9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

216778:DX03 RS13695
gene id: 216778:DX03_RS13695
uniprot id: A0A023Y5N2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

216778:DX03 RS14000
gene id: 216778:DX03_RS14000
uniprot id: A0A023Y5U0
names: Function
names: Similarity
messages: Belongs to the ribF family.
messages: Catalyzes the phosphorylation of riboflavin to FMN followed by the adenylation of FMN to FAD.

216778:DX03 RS16820
gene id: 216778:DX03_RS16820
uniprot id: A0A023Y7C8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP K family.
messages: Cell inner membrane
messages: Membrane

216778:DX03 RS05205
gene id: 216778:DX03_RS05205
uniprot id: A0A023Y0N2
names: Similarity
messages: Belongs to the PrpD family.

216778:DX03 RS10865
gene id: 216778:DX03_RS10865
uniprot id: A0A023Y3S1
names: Similarity
messages: Belongs to the threonine synthase family.

216778:DX03 RS10535
gene id: 216778:DX03_RS10535
uniprot id: A0A023Y3D0
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

216778:DX03 RS16750
gene id: 216778:DX03_RS16750
uniprot id: A0A023Y6Y5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane-bound acyltransferase family.
messages: Cell inner membrane
messages: Membrane

216778:DX03 RS18100
gene id: 216778:DX03_RS18100
uniprot id: A0A4U3G6F1
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

216778:DX03 RS19525
gene id: 216778:DX03_RS19525
uniprot id: A0A023Y8U1
names: Similarity
messages: Belongs to the glutamate synthase family.

216778:DX03 RS01945
gene id: 216778:DX03_RS01945
uniprot id: A0A023XZG4
names: Similarity
messages: Belongs to the arylamine N-acetyltransferase family.

216778:DX03 RS06040
gene id: 216778:DX03_RS06040
uniprot id: A0A023Y116
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmB subfamily.
messages: Methylates ribosomal protein uL3 on a specific glutamine residue.

216778:DX03 RS11505
gene id: 216778:DX03_RS11505
uniprot id: A0A023Y3U0
names: Function
names: Similarity
messages: Belongs to the SELO family.
messages: Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr or Tyr residues of target proteins (AMPylation).

216778:DX03 RS06150
gene id: 216778:DX03_RS06150
uniprot id: A0A023Y1R0
names: Similarity
messages: Belongs to the iron/ascorbate-dependent oxidoreductase family.

216778:DX03 RS19825
gene id: 216778:DX03_RS19825
uniprot id: A0A023Y8G4
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

216778:DX03 RS19765
gene id: 216778:DX03_RS19765
uniprot id: A0A023Y983
names: Similarity
messages: Belongs to the type-B carboxylesterase/lipase family.

216778:DX03 RS12970
gene id: 216778:DX03_RS12970
uniprot id: A0A023Y5C1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the hemerythrin family.
messages: Monomer.
messages: Oxygen-binding protein. May be involved in a storage mechanism or for delivery to oxygen-requiring enzymes. The oxygen-binding site contains two iron atoms.

216778:DX03 RS17260
gene id: 216778:DX03_RS17260
uniprot id: A0A023Y7A3
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

216778:DX03 RS10215
gene id: 216778:DX03_RS10215
uniprot id: A0A023Y3H8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

216778:DX03 RS04340
gene id: 216778:DX03_RS04340
uniprot id: A0A023Y0H5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Cell inner membrane
messages: Membrane

216778:DX03 RS03125
gene id: 216778:DX03_RS03125
uniprot id: A0A023Y071
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

216778:DX03 RS04620
gene id: 216778:DX03_RS04620
uniprot id: A0A023Y119
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ExbD/TolR family.
messages: Cell inner membrane
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

216778:DX03 RS14635
gene id: 216778:DX03_RS14635
uniprot id: A0A023Y661
names: Similarity
messages: Belongs to the peptidase C56 family.

216778:DX03 RS11555
gene id: 216778:DX03_RS11555
uniprot id: A0A023Y3V1
names: Subcellular Location Annotation
messages: Membrane

216778:DX03 RS06640
gene id: 216778:DX03_RS06640
uniprot id: A0A023Y153
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Belongs to the NnrE/AIBP family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

216778:DX03 RS12890
gene id: 216778:DX03_RS12890
uniprot id: A0A023Y5B0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Membrane

216778:DX03 RS01425
gene id: 216778:DX03_RS01425
uniprot id: A0A023XYF5
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

216778:DX03 RS05735
gene id: 216778:DX03_RS05735
uniprot id: A0A023Y0W3
names: Similarity
messages: Belongs to the thioredoxin family.

216778:DX03 RS06865
gene id: 216778:DX03_RS06865
uniprot id: A0A023Y243
names: Subcellular Location Annotation
messages: Membrane

216778:DX03 RS16670
gene id: 216778:DX03_RS16670
uniprot id: A0A023Y6P6
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion.
messages: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.
messages: In the C-terminal section; belongs to the HTP reductase family.
messages: In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family.

216778:DX03 RS05190
gene id: 216778:DX03_RS05190
uniprot id: A0A023Y1A0
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.

216778:DX03 RS10225
gene id: 216778:DX03_RS10225
uniprot id: A0A023Y428
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

216778:DX03 RS16410
gene id: 216778:DX03_RS16410
uniprot id: A0A023Y7D9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

216778:DX03 RS19190
gene id: 216778:DX03_RS19190
uniprot id: A0A023Y929
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

216778:DX03 RS16470
gene id: 216778:DX03_RS16470
uniprot id: A0A023Y6K5
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

216778:DX03 RS04385
gene id: 216778:DX03_RS04385
uniprot id: A0A023Y0S8
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
messages: In the C-terminal section; belongs to the NAD synthetase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

216778:DX03 RS05165
gene id: 216778:DX03_RS05165
uniprot id: A0A023Y196
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DoxX family.
messages: Membrane

216778:DX03 RS15875
gene id: 216778:DX03_RS15875
uniprot id: A0A023Y6J1
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

216778:DX03 RS04870
gene id: 216778:DX03_RS04870
uniprot id: A0A023Y0V7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0060 family.
messages: Cell membrane

216778:DX03 RS10230
gene id: 216778:DX03_RS10230
uniprot id: A0A023Y3U8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum
messages: Belongs to the FliD family.
messages: Homopentamer.
messages: Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.
messages: Secreted

216778:DX03 RS12145
gene id: 216778:DX03_RS12145
uniprot id: A0A023Y566
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

216778:DX03 RS11455
gene id: 216778:DX03_RS11455
uniprot id: A0A023Y3T1
names: Similarity
messages: Belongs to the class-II fumarase/aspartase family.

216778:DX03 RS13855
gene id: 216778:DX03_RS13855
uniprot id: A0A023Y5D2
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

216778:DX03 RS04645
gene id: 216778:DX03_RS04645
uniprot id: A0A023Y125
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CpoB family.
messages: Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division.
messages: Periplasm

216778:DX03 RS06220
gene id: 216778:DX03_RS06220
uniprot id: A0A023Y148
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

216778:DX03 RS12355
gene id: 216778:DX03_RS12355
uniprot id: A0A023Y4D6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.
messages: Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins.
messages: Cytoplasm

216778:DX03 RS13185
gene id: 216778:DX03_RS13185
uniprot id: A0A023Y522
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell outer membrane

216778:DX03 RS02640
gene id: 216778:DX03_RS02640
uniprot id: A0A023XZ03
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

216778:DX03 RS06835
gene id: 216778:DX03_RS06835
uniprot id: A0A023Y280
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm

216778:DX03 RS19640
gene id: 216778:DX03_RS19640
uniprot id: A0A023Y9C2
names: Subcellular Location Annotation
messages: Membrane

216778:DX03 RS15705
gene id: 216778:DX03_RS15705
uniprot id: A0A023Y763
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

216778:DX03 RS16855
gene id: 216778:DX03_RS16855
uniprot id: A0A4U3GJ70
names: Caution
names: Similarity
messages: Belongs to the peptidase S8 family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

216778:DX03 RS14660
gene id: 216778:DX03_RS14660
uniprot id: A0A023Y667
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

216778:DX03 RS07145
gene id: 216778:DX03_RS07145
uniprot id: A0A023Y1Q4
names: Subcellular Location Annotation
messages: Membrane

216778:DX03 RS04205
gene id: 216778:DX03_RS04205
uniprot id: A0A023Y0N9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

216778:DX03 RS19415
gene id: 216778:DX03_RS19415
uniprot id: A0A023Y971
names: Similarity
messages: Belongs to the peptidase U62 family.

216778:DX03 RS16780
gene id: 216778:DX03_RS16780
uniprot id: A0A023Y7P7
names: Similarity
messages: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.

216778:DX03 RS01880
gene id: 216778:DX03_RS01880
uniprot id: A0A023XYH8
names: Subcellular Location Annotation
messages: Membrane

216778:DX03 RS02300
gene id: 216778:DX03_RS02300
uniprot id: A0A023XZS4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

216778:DX03 RS19410
gene id: 216778:DX03_RS19410
uniprot id: A0A023Y8F9
names: Similarity
messages: Belongs to the peptidase U62 family.

216778:DX03 RS06175
gene id: 216778:DX03_RS06175
uniprot id: A0A4U3G992
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 20 kDa subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

216778:DX03 RS15380
gene id: 216778:DX03_RS15380
uniprot id: A0A023Y6N3
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

216778:DX03 RS04095
gene id: 216778:DX03_RS04095
uniprot id: A0A023XZZ0
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

216778:DX03 RS00110
gene id: 216778:DX03_RS00110
uniprot id: A0A023XXT7
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

216778:DX03 RS15595
gene id: 216778:DX03_RS15595
uniprot id: A0A023Y6F0
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

216778:DX03 RS03545
gene id: 216778:DX03_RS03545
uniprot id: A0A023XZF3
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

216778:DX03 RS03265
gene id: 216778:DX03_RS03265
uniprot id: A0A023XZV7
names: Similarity
messages: Belongs to the FrmR/RcnR family.

216778:DX03 RS05330
gene id: 216778:DX03_RS05330
uniprot id: A0A023Y0H3
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

216778:DX03 RS03280
gene id: 216778:DX03_RS03280
uniprot id: A0A023Y095
names: Function
names: Similarity
messages: Belongs to the esterase D family.
messages: Serine hydrolase involved in the detoxification of formaldehyde.

216778:DX03 RS03915
gene id: 216778:DX03_RS03915
uniprot id: A0A023XZM3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

216778:DX03 RS01310
gene id: 216778:DX03_RS01310
uniprot id: A0A023XYS0
names: Subcellular Location Annotation
messages: Membrane

216778:DX03 RS08200
gene id: 216778:DX03_RS08200
uniprot id: A0A023Y2W8
names: Subcellular Location Annotation
messages: Membrane

216778:DX03 RS18420
gene id: 216778:DX03_RS18420
uniprot id: A0A023Y7P9
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

216778:DX03 RS04150
gene id: 216778:DX03_RS04150
uniprot id: A0A023Y0R8
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

216778:DX03 RS16195
gene id: 216778:DX03_RS16195
uniprot id: A0A023Y6G2
names: Similarity
messages: Belongs to the UbiH/COQ6 family.

216778:DX03 RS14280
gene id: 216778:DX03_RS14280
uniprot id: A0A023Y5Z0
names: Subcellular Location Annotation
messages: Membrane

216778:DX03 RS14785
gene id: 216778:DX03_RS14785
uniprot id: A0A023Y6I4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

216778:DX03 RS02790
gene id: 216778:DX03_RS02790
uniprot id: A0A023XZ22
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

216778:DX03 RS00120
gene id: 216778:DX03_RS00120
uniprot id: A0A023XYG5
names: Cofactor
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.
messages: Probably binds two magnesium or manganese ions per subunit.

216778:DX03 RS14560
gene id: 216778:DX03_RS14560
uniprot id: A0A023Y643
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

216778:DX03 RS11460
gene id: 216778:DX03_RS11460
uniprot id: A0A023Y424
names: Similarity
messages: Belongs to the intradiol ring-cleavage dioxygenase family.

216778:DX03 RS01300
gene id: 216778:DX03_RS01300
uniprot id: A0A023XZ46
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit F family.
messages: Cell membrane
messages: Membrane

216778:DX03 RS03920
gene id: 216778:DX03_RS03920
uniprot id: A0A023XZU8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

216778:DX03 RS16225
gene id: 216778:DX03_RS16225
uniprot id: A0A023Y6P3
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PdxA family.
messages: Binds 1 divalent metal cation per subunit. Can use ions such as Zn(2+), Mg(2+) or Co(2+).
messages: Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L-threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP).
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The active site is located at the dimer interface.

216778:DX03 RS07130
gene id: 216778:DX03_RS07130
uniprot id: A0A023Y296
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

216778:DX03 RS10640
gene id: 216778:DX03_RS10640
uniprot id: A0A023Y3N9
names: Similarity
messages: Belongs to the HMG-CoA lyase family.

216778:DX03 RS07125
gene id: 216778:DX03_RS07125
uniprot id: A0A023Y2E1
names: Similarity
messages: Belongs to the ribonuclease N1/T1 family.

216778:DX03 RS10300
gene id: 216778:DX03_RS10300
uniprot id: A0A023Y438
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliJ family.
messages: Cell membrane
messages: Membrane

216778:DX03 RS15695
gene id: 216778:DX03_RS15695
uniprot id: A0A023Y680
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

216778:DX03 RS02935
gene id: 216778:DX03_RS02935
uniprot id: A0A023XZQ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEDS family. MrdB/RodA subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Peptidoglycan polymerase that is essential for cell wall elongation.

216778:DX03 RS16265
gene id: 216778:DX03_RS16265
uniprot id: A0A023Y714
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell membrane

216778:DX03 RS12130
gene id: 216778:DX03_RS12130
uniprot id: A0A023Y483
names: Function
names: Similarity
messages: Belongs to the HPPK family.
messages: Catalyzes the transfer of pyrophosphate from adenosine triphosphate (ATP) to 6-hydroxymethyl-7,8-dihydropterin, an enzymatic step in folate biosynthesis pathway.

216778:DX03 RS20195
gene id: 216778:DX03_RS20195
uniprot id: A0A023Y8Q3
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

216778:DX03 RS17020
gene id: 216778:DX03_RS17020
uniprot id: A0A023Y7Q1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Binds 1 Mg(2+) ion per monomer.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

216778:DX03 RS12325
gene id: 216778:DX03_RS12325
uniprot id: A0A023Y4Y6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

216778:DX03 RS04655
gene id: 216778:DX03_RS04655
uniprot id: A0A023Y0P8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the QueC family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).

216778:DX03 RS04380
gene id: 216778:DX03_RS04380
uniprot id: A0A023Y0W6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

216778:DX03 RS06955
gene id: 216778:DX03_RS06955
uniprot id: A0A023Y1C6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbE subfamily.
messages: Cell inner membrane

216778:DX03 RS01980
gene id: 216778:DX03_RS01980
uniprot id: A0A023XZ66
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

216778:DX03 RS07230
gene id: 216778:DX03_RS07230
uniprot id: A0A023Y2C0
names: Similarity
messages: Belongs to the ArsC family.

216778:DX03 RS18750
gene id: 216778:DX03_RS18750
uniprot id: A0A023Y8E1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sirtuin family. Class II subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form.

216778:DX03 RS15760
gene id: 216778:DX03_RS15760
uniprot id: A0A023Y726
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

216778:DX03 RS03185
gene id: 216778:DX03_RS03185
uniprot id: A0A023Y049
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

216778:DX03 RS07090
gene id: 216778:DX03_RS07090
uniprot id: A0A023Y1P5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

216778:DX03 RS13535
gene id: 216778:DX03_RS13535
uniprot id: A0A023Y5K1
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

216778:DX03 RS13845
gene id: 216778:DX03_RS13845
uniprot id: A0A023Y5R2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

216778:DX03 RS12225
gene id: 216778:DX03_RS12225
uniprot id: A0A023Y4A3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

216778:DX03 RS05660
gene id: 216778:DX03_RS05660
uniprot id: A0A023Y0V2
names: Similarity
messages: Belongs to the RutC family.

216778:DX03 RS12065
gene id: 216778:DX03_RS12065
uniprot id: A0A023Y551
names: Function
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.
messages: Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.

216778:DX03 RS12360
gene id: 216778:DX03_RS12360
uniprot id: A0A023Y4L5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SurE nucleotidase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Cytoplasm
messages: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.

216778:DX03 RS01675
gene id: 216778:DX03_RS01675
uniprot id: A0A023XYZ7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoH subfamily.
messages: Cytoplasm
messages: Interacts with the RNA polymerase core enzyme.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes.

216778:DX03 RS18530
gene id: 216778:DX03_RS18530
uniprot id: A0A023Y7R6
names: Function
names: Similarity
messages: Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon.
messages: Belongs to the biotin--protein ligase family.

216778:DX03 RS07175
gene id: 216778:DX03_RS07175
uniprot id: A0A023Y2F2
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

216778:DX03 RS03175
gene id: 216778:DX03_RS03175
uniprot id: A0A023XZF9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbA subfamily.
messages: Periplasm

216778:DX03 RS10465
gene id: 216778:DX03_RS10465
uniprot id: A0A023Y3L3
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

216778:DX03 RS12695
gene id: 216778:DX03_RS12695
uniprot id: A0A023Y4M6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP H family.
messages: Cell inner membrane
messages: Membrane

216778:DX03 RS14575
gene id: 216778:DX03_RS14575
uniprot id: A0A023Y6I3
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

216778:DX03 RS07750
gene id: 216778:DX03_RS07750
uniprot id: A0A023Y1W8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metallo-dependent hydrolases superfamily. HutI family.
messages: Binds 1 zinc or iron ion per subunit.
messages: Catalyzes the hydrolytic cleavage of the carbon-nitrogen bond in imidazolone-5-propanoate to yield N-formimidoyl-L-glutamate. It is the third step in the universal histidine degradation pathway.
messages: Cytoplasm

216778:DX03 RS04945
gene id: 216778:DX03_RS04945
uniprot id: A0A023Y0X7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

216778:DX03 RS05370
gene id: 216778:DX03_RS05370
uniprot id: A0A023Y1C7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptide transporter carbon starvation (CstA) (TC 2.A.114) family.
messages: Membrane

216778:DX03 RS05215
gene id: 216778:DX03_RS05215
uniprot id: A0A023Y1A4
names: Similarity
messages: In the C-terminal section; belongs to the transpeptidase family.
messages: In the N-terminal section; belongs to the glycosyltransferase 51 family.

216778:DX03 RS12725
gene id: 216778:DX03_RS12725
uniprot id: A0A023Y4V5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)- to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Homodimer.

216778:DX03 RS19405
gene id: 216778:DX03_RS19405
uniprot id: A0A023Y876
names: Similarity
messages: Belongs to the peptidase U62 family.

216778:DX03 RS15835
gene id: 216778:DX03_RS15835
uniprot id: A0A023Y740
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

216778:DX03 RS16505
gene id: 216778:DX03_RS16505
uniprot id: A0A023Y7J1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

216778:DX03 RS16640
gene id: 216778:DX03_RS16640
uniprot id: A0A023Y792
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

216778:DX03 RS19375
gene id: 216778:DX03_RS19375
uniprot id: A0A023Y8R0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

216778:DX03 RS13235
gene id: 216778:DX03_RS13235
uniprot id: A0A023Y5P2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell outer membrane

216778:DX03 RS05595
gene id: 216778:DX03_RS05595
uniprot id: A0A023Y1G5
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

216778:DX03 RS18080
gene id: 216778:DX03_RS18080
uniprot id: A0A023Y8J8
names: Subcellular Location Annotation
messages: Membrane

216778:DX03 RS03470
gene id: 216778:DX03_RS03470
uniprot id: A0A023XZE2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Responsible for the transport of dicarboxylates such as succinate, fumarate, and malate across the membrane.

216778:DX03 RS15775
gene id: 216778:DX03_RS15775
uniprot id: A0A023Y6H6
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

216778:DX03 RS09055
gene id: 216778:DX03_RS09055
uniprot id: A0A023Y328
names: Similarity
messages: Belongs to the peptidase A24 family.

216778:DX03 RS10490
gene id: 216778:DX03_RS10490
uniprot id: A0A023Y3L7
names: Cofactor
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.
messages: Binds 1 [4Fe-4S] cluster per subunit.

216778:DX03 RS16385
gene id: 216778:DX03_RS16385
uniprot id: A0A023Y7D4
names: Function
names: Similarity
messages: Belongs to the Dus family. DusB subfamily.
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

216778:DX03 RS19590
gene id: 216778:DX03_RS19590
uniprot id: A0A023Y9B3
names: Similarity
messages: Belongs to the UPF0502 family.

216778:DX03 RS01360
gene id: 216778:DX03_RS01360
uniprot id: A0A023XZ38
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the diacylglycerol/lipid kinase family. YegS lipid kinase subfamily.
messages: Binds 1 Mg(2+) ion per subunit. Ca(2+) may be able to substitute.
messages: Cytoplasm
messages: Probably phosphorylates lipids; the in vivo substrate is unknown.

216778:DX03 RS16930
gene id: 216778:DX03_RS16930
uniprot id: A0A4U3GF90
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acetylates the N-terminal alanine of ribosomal protein bS18.
messages: Belongs to the acetyltransferase family. RimI subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

216778:DX03 RS12180
gene id: 216778:DX03_RS12180
uniprot id: A0A023Y4V8
names: Similarity
messages: Belongs to the PhoH family.

216778:DX03 RS08765
gene id: 216778:DX03_RS08765
uniprot id: A0A023Y2K3
names: Similarity
messages: Belongs to the VgrG protein family.

216778:DX03 RS07795
gene id: 216778:DX03_RS07795
uniprot id: A0A023Y2G1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

216778:DX03 RS06735
gene id: 216778:DX03_RS06735
uniprot id: A0A023Y212
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily. UbiG/COQ3 family.
messages: O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway.

216778:DX03 RS14795
gene id: 216778:DX03_RS14795
uniprot id: A0A023Y5P0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

216778:DX03 RS06720
gene id: 216778:DX03_RS06720
uniprot id: A0A023Y1F8
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Alleviates ribosome stalling that occurs when 3 or more consecutive Pro residues or the sequence PPG is present in a protein, possibly by augmenting the peptidyl transferase activity of the ribosome. Modification of Lys-34 is required for alleviation.
messages: May be beta-lysylated on the epsilon-amino group of Lys-34 by the combined action of EpmA and EpmB, and then hydroxylated on the C5 position of the same residue by EpmC (if this protein is present). Lysylation is critical for the stimulatory effect of EF-P on peptide-bond formation. The lysylation moiety may extend toward the peptidyltransferase center and stabilize the terminal 3-CCA end of the tRNA. Hydroxylation of the C5 position on Lys-34 may allow additional potential stabilizing hydrogen-bond interactions with the P-tRNA.

216778:DX03 RS05625
gene id: 216778:DX03_RS05625
uniprot id: A0A023Y171
names: Similarity
messages: Belongs to the YjdM family.

216778:DX03 RS17105
gene id: 216778:DX03_RS17105
uniprot id: A0A023Y6Y1
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

216778:DX03 RS18510
gene id: 216778:DX03_RS18510
uniprot id: A0A023Y8R8
names: Cofactor
names: Similarity
messages: Belongs to the arginase family.
messages: Binds 2 manganese ions per subunit.

216778:DX03 RS11600
gene id: 216778:DX03_RS11600
uniprot id: A0A023Y4J2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

216778:DX03 RS05070
gene id: 216778:DX03_RS05070
uniprot id: A0A023Y0Z8
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

216778:DX03 RS15325
gene id: 216778:DX03_RS15325
uniprot id: A0A023Y712
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase H family.
messages: Binds 1 Mg(2+) ion per subunit. May bind a second metal ion at a regulatory site, or after substrate binding.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Monomer.

216778:DX03 RS17720
gene id: 216778:DX03_RS17720
uniprot id: A0A023Y864
names: Similarity
messages: Belongs to the nitroreductase family. HadB/RutE subfamily.

216778:DX03 RS06260
gene id: 216778:DX03_RS06260
uniprot id: A0A023Y1W0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

216778:DX03 RS05850
gene id: 216778:DX03_RS05850
uniprot id: A0A023Y1L0
names: Cofactor
names: Similarity
messages: Belongs to the alkaline phosphatase family.
messages: Binds 1 Mg(2+) ion.
messages: Binds 2 Zn(2+) ions.

216778:DX03 RS16140
gene id: 216778:DX03_RS16140
uniprot id: A0A023Y6Y9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.
messages: Serves to protect the cell against DNA damage by alkyl hydroperoxides. It can use either NADH or NADPH as electron donor for direct reduction of redox dyes or of alkyl hydroperoxides when combined with the AhpC protein.

216778:DX03 RS13585
gene id: 216778:DX03_RS13585
uniprot id: A0A023Y5L1
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MGMT family.
messages: Cytoplasm
messages: Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
messages: This enzyme catalyzes only one turnover and therefore is not strictly catalytic. According to one definition, an enzyme is a biocatalyst that acts repeatedly and over many reaction cycles.

216778:DX03 RS06130
gene id: 216778:DX03_RS06130
uniprot id: A0A023Y1G6
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

216778:DX03 RS10470
gene id: 216778:DX03_RS10470
uniprot id: A0A023Y4A6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

216778:DX03 RS09095
gene id: 216778:DX03_RS09095
uniprot id: A0A023Y3G0
names: Similarity
messages: Belongs to the oxygen-dependent FAD-linked oxidoreductase family.

216778:DX03 RS09360
gene id: 216778:DX03_RS09360
uniprot id: A0A023Y3H9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

216778:DX03 RS07540
gene id: 216778:DX03_RS07540
uniprot id: A0A023Y2L4
names: Similarity
messages: Belongs to the HesB/IscA family.

216778:DX03 RS01225
gene id: 216778:DX03_RS01225
uniprot id: A0A023XZ31
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta chain.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).

216778:DX03 RS18115
gene id: 216778:DX03_RS18115
uniprot id: A0A023Y852
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KdpC family.
messages: Cell membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

216778:DX03 RS14895
gene id: 216778:DX03_RS14895
uniprot id: A0A023Y5R8
names: Subcellular Location Annotation
messages: Cytoplasm

216778:DX03 RS17060
gene id: 216778:DX03_RS17060
uniprot id: A0A023Y756
names: Subcellular Location Annotation
messages: Membrane

216778:DX03 RS16480
gene id: 216778:DX03_RS16480
uniprot id: A0A023Y7I7
names: Similarity
messages: Belongs to the Nudix hydrolase family.

216778:DX03 RS00330
gene id: 216778:DX03_RS00330
uniprot id: A0A023XXP8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Cell inner membrane
messages: Membrane

216778:DX03 RS01235
gene id: 216778:DX03_RS01235
uniprot id: A0A023XYQ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.
messages: Membrane

216778:DX03 RS00970
gene id: 216778:DX03_RS00970
uniprot id: A0A023XY78
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family.
messages: Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate.
messages: Cell inner membrane

216778:DX03 RS04500
gene id: 216778:DX03_RS04500
uniprot id: A0A023Y000
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

216778:DX03 RS14520
gene id: 216778:DX03_RS14520
uniprot id: A0A023Y5S1
names: Subcellular Location Annotation
messages: Membrane

216778:DX03 RS08535
gene id: 216778:DX03_RS08535
uniprot id: A0A023Y278
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

216778:DX03 RS18580
gene id: 216778:DX03_RS18580
uniprot id: A0A023Y7S7
names: Similarity
messages: Belongs to the OsmC/Ohr family.

216778:DX03 RS00135
gene id: 216778:DX03_RS00135
uniprot id: A0A023XXU0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the N7 position of guanine in position 527 of 16S rRNA.

216778:DX03 RS15170
gene id: 216778:DX03_RS15170
uniprot id: A0A023Y6J6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

216778:DX03 RS16260
gene id: 216778:DX03_RS16260
uniprot id: A0A023Y7B2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

216778:DX03 RS06055
gene id: 216778:DX03_RS06055
uniprot id: A0A023Y1F0
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

216778:DX03 RS05160
gene id: 216778:DX03_RS05160
uniprot id: A0A023Y1D8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the pyridoxamine 5'-phosphate oxidase family.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

216778:DX03 RS04240
gene id: 216778:DX03_RS04240
uniprot id: A0A023XZT7
names: Subcellular Location Annotation
messages: Endoplasmic reticulum
messages: Golgi apparatus
messages: Lysosome

216778:DX03 RS10025
gene id: 216778:DX03_RS10025
uniprot id: A0A023Y3Y9
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

216778:DX03 RS14750
gene id: 216778:DX03_RS14750
uniprot id: A0A023Y6L9
names: Similarity
messages: Belongs to the YkuD family.

216778:DX03 RS18155
gene id: 216778:DX03_RS18155
uniprot id: A0A023Y8L0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

216778:DX03 RS19805
gene id: 216778:DX03_RS19805
uniprot id: A0A023Y8Q6
names: Similarity
messages: Belongs to the KHG/KDPG aldolase family.

216778:DX03 RS20175
gene id: 216778:DX03_RS20175
uniprot id: A0A023Y8Y4
names: Function
names: Similarity
names: Subunit
messages: A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD.
messages: Belongs to the RecD family.
messages: Heterotrimer of RecB, RecC and RecD. All subunits contribute to DNA-binding.

216778:DX03 RS03645
gene id: 216778:DX03_RS03645
uniprot id: A0A023Y0C8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

216778:DX03 RS03100
gene id: 216778:DX03_RS03100
uniprot id: A0A023Y066
names: Cofactor
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: A single active site specifically recognizes both ATP and CTP and is responsible for their addition.
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. Bacterial CCA-adding enzyme type 1 subfamily.
messages: Catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. tRNA 3'-terminal CCA addition is required both for tRNA processing and repair. Also involved in tRNA surveillance by mediating tandem CCA addition to generate a CCACCA at the 3' terminus of unstable tRNAs. While stable tRNAs receive only 3'-terminal CCA, unstable tRNAs are marked with CCACCA and rapidly degraded.
messages: Comprises two domains: an N-terminal domain containing the nucleotidyltransferase activity and a C-terminal HD domain associated with both phosphodiesterase and phosphatase activities.
messages: Magnesium is required for nucleotidyltransferase activity.
messages: Monomer. Can also form homodimers and oligomers.
messages: Nickel for phosphatase activity.

216778:DX03 RS07345
gene id: 216778:DX03_RS07345
uniprot id: A0A023Y1M6
names: Subcellular Location Annotation
messages: Membrane

216778:DX03 RS00880
gene id: 216778:DX03_RS00880
uniprot id: A0A023XYI2
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.

216778:DX03 RS15750
gene id: 216778:DX03_RS15750
uniprot id: A0A023Y6H2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

216778:DX03 RS13415
gene id: 216778:DX03_RS13415
uniprot id: A0A023Y4Y5
names: Subcellular Location Annotation
messages: Cytoplasm

216778:DX03 RS06630
gene id: 216778:DX03_RS06630
uniprot id: A0A023Y1Z3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseA family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

216778:DX03 RS13295
gene id: 216778:DX03_RS13295
uniprot id: A0A023Y4W1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family.
messages: Cytoplasm
messages: Homotrimer.

216778:DX03 RS11200
gene id: 216778:DX03_RS11200
uniprot id: A0A023Y4B2
names: Similarity
messages: Belongs to the SsuE family.

216778:DX03 RS13285
gene id: 216778:DX03_RS13285
uniprot id: A0A023Y5Q0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M20A family. DapE subfamily.
messages: Binds 2 Zn(2+) or Co(2+) ions per subunit.
messages: Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls.
messages: Homodimer.

216778:DX03 RS14475
gene id: 216778:DX03_RS14475
uniprot id: A0A023Y6B6
names: Caution
names: Function
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.

216778:DX03 RS01385
gene id: 216778:DX03_RS01385
uniprot id: A0A023XZ44
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

216778:DX03 RS19045
gene id: 216778:DX03_RS19045
uniprot id: A0A023Y8V0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

216778:DX03 RS13650
gene id: 216778:DX03_RS13650
uniprot id: A0A023Y523
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 zinc ion per subunit.

216778:DX03 RS00885
gene id: 216778:DX03_RS00885
uniprot id: A0A023XXZ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

216778:DX03 RS00980
gene id: 216778:DX03_RS00980
uniprot id: A0A023XYW4
names: Similarity
messages: Belongs to the HsdR family.

216778:DX03 RS05815
gene id: 216778:DX03_RS05815
uniprot id: A0A023Y0X5
names: Similarity
messages: Belongs to the UPF0307 family.

216778:DX03 RS19720
gene id: 216778:DX03_RS19720
uniprot id: A0A023Y8Y0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the KduI family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the isomerization of 5-dehydro-4-deoxy-D-glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate.

216778:DX03 RS04220
gene id: 216778:DX03_RS04220
uniprot id: A0A023Y018
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell inner membrane
messages: Membrane

216778:DX03 RS19230
gene id: 216778:DX03_RS19230
uniprot id: A0A023Y840
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Involved in a late step of protoheme IX synthesis.
messages: Membrane

216778:DX03 RS10485
gene id: 216778:DX03_RS10485
uniprot id: A0A023Y3C5
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CheB family.
messages: Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.
messages: Cytoplasm
messages: Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
messages: Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity.

216778:DX03 RS03295
gene id: 216778:DX03_RS03295
uniprot id: A0A023XZA9
names: Similarity
messages: Belongs to the YkuD family.

216778:DX03 RS17805
gene id: 216778:DX03_RS17805
uniprot id: A0A023Y7H0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

216778:DX03 RS11470
gene id: 216778:DX03_RS11470
uniprot id: A0A023Y4N5
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

216778:DX03 RS00060
gene id: 216778:DX03_RS00060
uniprot id: A0A023XXS7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

216778:DX03 RS17330
gene id: 216778:DX03_RS17330
uniprot id: A0A023Y737
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MotA family.
messages: Membrane

216778:DX03 RS13080
gene id: 216778:DX03_RS13080
uniprot id: A0A023Y4T0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

216778:DX03 RS03565
gene id: 216778:DX03_RS03565
uniprot id: A0A023Y019
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.

216778:DX03 RS01735
gene id: 216778:DX03_RS01735
uniprot id: A0A023XYM3
names: Similarity
messages: Belongs to the transcriptional regulatory Fis family.

216778:DX03 RS16010
gene id: 216778:DX03_RS16010
uniprot id: A0A023Y767
names: Similarity
messages: Belongs to the WrbA family.

216778:DX03 RS11515
gene id: 216778:DX03_RS11515
uniprot id: A0A023Y4T1
names: Subcellular Location Annotation
messages: Cytoplasm

216778:DX03 RS18905
gene id: 216778:DX03_RS18905
uniprot id: A0A023Y7Y1
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Homododecamer.

216778:DX03 RS00815
gene id: 216778:DX03_RS00815
uniprot id: A0A023XY48
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. Biotin synthase family.
messages: Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
messages: Homodimer.

216778:DX03 RS13975
gene id: 216778:DX03_RS13975
uniprot id: A0A023Y5T5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM86 family.
messages: Membrane

216778:DX03 RS06050
gene id: 216778:DX03_RS06050
uniprot id: A0A023Y1P4
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

216778:DX03 RS01390
gene id: 216778:DX03_RS01390
uniprot id: A0A023XYT5
names: Similarity
messages: Belongs to the TrpC family.

216778:DX03 RS15385
gene id: 216778:DX03_RS15385
uniprot id: A0A023Y644
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

216778:DX03 RS19790
gene id: 216778:DX03_RS19790
uniprot id: A0A023Y988
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

216778:DX03 RS06700
gene id: 216778:DX03_RS06700
uniprot id: A0A023Y251
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.
messages: Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA.
messages: Cytoplasm
messages: Homodimer.

216778:DX03 RS17025
gene id: 216778:DX03_RS17025
uniprot id: A0A023Y7G3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
messages: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.
messages: Homodimer.

216778:DX03 RS13605
gene id: 216778:DX03_RS13605
uniprot id: A0A023Y5V6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

216778:DX03 RS18230
gene id: 216778:DX03_RS18230
uniprot id: A0A023Y8M3
names: Subcellular Location Annotation
messages: Membrane

216778:DX03 RS04525
gene id: 216778:DX03_RS04525
uniprot id: A0A023Y007
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

216778:DX03 RS03610
gene id: 216778:DX03_RS03610
uniprot id: A0A023Y0C3
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the gamma-glutamyltransferase family.
messages: Cleaved by autocatalysis into a large and a small subunit.
messages: This enzyme consists of two polypeptide chains, which are synthesized in precursor form from a single polypeptide.

216778:DX03 RS13180
gene id: 216778:DX03_RS13180
uniprot id: A0A023Y4U3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

216778:DX03 RS19290
gene id: 216778:DX03_RS19290
uniprot id: A0A023Y946
names: Function
messages: Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and/or cell division.

216778:DX03 RS06775
gene id: 216778:DX03_RS06775
uniprot id: A0A023Y179
names: Subcellular Location Annotation
messages: Membrane

216778:DX03 RS07140
gene id: 216778:DX03_RS07140
uniprot id: A0A023Y1H4
names: Subcellular Location Annotation
messages: Membrane

216778:DX03 RS00080
gene id: 216778:DX03_RS00080
uniprot id: A0A023XXL1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

216778:DX03 RS18560
gene id: 216778:DX03_RS18560
uniprot id: A0A023Y801
names: Function
names: Similarity
messages: Belongs to the Dus family. DusA subfamily.
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U20 and U20a in tRNAs.

216778:DX03 RS15000
gene id: 216778:DX03_RS15000
uniprot id: A0A023Y628
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

216778:DX03 RS17765
gene id: 216778:DX03_RS17765
uniprot id: A0A023Y8E3
names: Similarity
messages: Belongs to the 2-oxoadipate dioxygenase/decarboxylase family.

216778:DX03 RS16190
gene id: 216778:DX03_RS16190
uniprot id: A0A023Y6Z8
names: Similarity
messages: Belongs to the UbiH/COQ6 family.

216778:DX03 RS01315
gene id: 216778:DX03_RS01315
uniprot id: A0A023XY69
names: Subcellular Location Annotation
messages: Membrane

216778:DX03 RS13225
gene id: 216778:DX03_RS13225
uniprot id: A0A023Y526
names: Subcellular Location Annotation
messages: Membrane

216778:DX03 RS08645
gene id: 216778:DX03_RS08645
uniprot id: A0A023Y375
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.
messages: Catalyzes the conversion of L-lactate to pyruvate. Is coupled to the respiratory chain.
messages: Cell membrane

216778:DX03 RS10725
gene id: 216778:DX03_RS10725
uniprot id: A0A023Y4A5
names: Subcellular Location Annotation
messages: Membrane

216778:DX03 RS03460
gene id: 216778:DX03_RS03460
uniprot id: A0A023Y097
names: Subcellular Location Annotation
messages: Membrane

216778:DX03 RS18855
gene id: 216778:DX03_RS18855
uniprot id: A0A023Y7X3
names: Subcellular Location Annotation
messages: Cytoplasm

216778:DX03 RS17030
gene id: 216778:DX03_RS17030
uniprot id: A0A023Y6W5
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

216778:DX03 RS06160
gene id: 216778:DX03_RS06160
uniprot id: A0A023Y0W1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

216778:DX03 RS12035
gene id: 216778:DX03_RS12035
uniprot id: A0A023Y4F2
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Membrane
messages: Membrane-anchoring subunit of succinate dehydrogenase (SDH).
messages: Part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur protein, plus two membrane-anchoring proteins, SdhC and SdhD.

216778:DX03 RS16535
gene id: 216778:DX03_RS16535
uniprot id: A0A023Y7F9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEDS family. FtsW subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Peptidoglycan polymerase that is essential for cell division.

216778:DX03 RS13820
gene id: 216778:DX03_RS13820
uniprot id: A0A023Y5Q6
names: Similarity
messages: Belongs to the HSP15 family.

216778:DX03 RS17745
gene id: 216778:DX03_RS17745
uniprot id: A0A023Y870
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily.
messages: Cell inner membrane
messages: Involved in the import of queuosine (Q) precursors, required for Q precursor salvage.

216778:DX03 RS01090
gene id: 216778:DX03_RS01090
uniprot id: A0A023XY26
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiK family.
messages: Cytoplasm
messages: Required for efficient ubiquinone (coenzyme Q) biosynthesis. UbiK is probably an accessory factor of Ubi enzymes and facilitates ubiquinone biosynthesis by acting as an assembly factor, a targeting factor, or both.

216778:DX03 RS09275
gene id: 216778:DX03_RS09275
uniprot id: A0A023Y2V8
names: Subcellular Location Annotation
messages: Membrane

216778:DX03 RS06780
gene id: 216778:DX03_RS06780
uniprot id: A0A023Y1H0
names: Similarity
messages: Belongs to the SufE family.

216778:DX03 RS12110
gene id: 216778:DX03_RS12110
uniprot id: A0A023Y4H0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm

216778:DX03 RS02915
gene id: 216778:DX03_RS02915
uniprot id: A0A023XZ42
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

216778:DX03 RS06710
gene id: 216778:DX03_RS06710
uniprot id: A0A023Y1S1
names: Subcellular Location Annotation
messages: Membrane

216778:DX03 RS12730
gene id: 216778:DX03_RS12730
uniprot id: A0A023Y5L4
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

216778:DX03 RS05080
gene id: 216778:DX03_RS05080
uniprot id: A0A023Y0L3
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

216778:DX03 RS19990
gene id: 216778:DX03_RS19990
uniprot id: A0A023Y9J9
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Binds two Mg(2+) per subunit. The magnesium ions form salt bridges with both the protein and the DNA. Can also accept other divalent metal cations, such as Mn(2+) or Ca(2+).
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

216778:DX03 RS13715
gene id: 216778:DX03_RS13715
uniprot id: A0A023Y5X5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: Homodimer.

216778:DX03 RS05140
gene id: 216778:DX03_RS05140
uniprot id: A0A023Y192
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
messages: Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).
messages: Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

216778:DX03 RS12905
gene id: 216778:DX03_RS12905
uniprot id: A0A023Y5P1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

216778:DX03 RS07715
gene id: 216778:DX03_RS07715
uniprot id: A0A023Y2N8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

216778:DX03 RS15960
gene id: 216778:DX03_RS15960
uniprot id: A0A023Y758
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.

216778:DX03 RS12740
gene id: 216778:DX03_RS12740
uniprot id: A0A023Y588
names: Function
names: Similarity
messages: Belongs to the NadC/ModD family.
messages: Involved in the catabolism of quinolinic acid (QA).

216778:DX03 RS16030
gene id: 216778:DX03_RS16030
uniprot id: A0A023Y7B0
names: Similarity
messages: Belongs to the peptidase S8 family.

216778:DX03 RS01640
gene id: 216778:DX03_RS01640
uniprot id: A0A023XZB7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
messages: Cell inner membrane
messages: Forms a membrane-associated complex with FtsE.
messages: Membrane
messages: Part of the ABC transporter FtsEX involved in cellular division.

216778:DX03 RS17900
gene id: 216778:DX03_RS17900
uniprot id: A0A023Y828
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

216778:DX03 RS10020
gene id: 216778:DX03_RS10020
uniprot id: A0A023Y421
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsK/SpoIIIE/SftA family.
messages: Essential cell division protein that coordinates cell division and chromosome segregation. The N-terminus is involved in assembly of the cell-division machinery. The C-terminus functions as a DNA motor that moves dsDNA in an ATP-dependent manner towards the dif recombination site, which is located within the replication terminus region. Translocation stops specifically at Xer-dif sites, where FtsK interacts with the Xer recombinase, allowing activation of chromosome unlinking by recombination. FtsK orienting polar sequences (KOPS) guide the direction of DNA translocation. FtsK can remove proteins from DNA as it translocates, but translocation stops specifically at XerCD-dif site, thereby preventing removal of XerC and XerD from dif.
messages: Homohexamer. Forms a ring that surrounds DNA.
messages: Membrane

216778:DX03 RS12375
gene id: 216778:DX03_RS12375
uniprot id: A0A023Y500
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IspF family.
messages: Binds 1 divalent metal cation per subunit.
messages: Homotrimer.
messages: Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

216778:DX03 RS02435
gene id: 216778:DX03_RS02435
uniprot id: A0A023XZI3
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

216778:DX03 RS14695
gene id: 216778:DX03_RS14695
uniprot id: A0A023Y5W4
names: Cofactor
messages: Binds 1 Fe(2+) ion per subunit.

216778:DX03 RS02255
gene id: 216778:DX03_RS02255
uniprot id: A0A023XZD4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

216778:DX03 RS11935
gene id: 216778:DX03_RS11935
uniprot id: A0A023Y4C8
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
messages: Allosterically activated by GTP.
messages: Belongs to the UPRTase family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.
messages: Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.

216778:DX03 RS12870
gene id: 216778:DX03_RS12870
uniprot id: A0A023Y4Q1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

216778:DX03 RS03510
gene id: 216778:DX03_RS03510
uniprot id: A0A023Y0A6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LpxL/LpxM/LpxP family.
messages: Catalyzes the transfer of an acyl chain from an acyl-[acyl-carrier-protein] (ACP) to a Kdo(2)-lipid IV(A) to form a Kdo(2)-(acyl)-lipid IV(A).
messages: Cell inner membrane

216778:DX03 RS11915
gene id: 216778:DX03_RS11915
uniprot id: A0A023Y521
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PPase family.
messages: Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
messages: Cytoplasm
messages: Homohexamer.

216778:DX03 RS15390
gene id: 216778:DX03_RS15390
uniprot id: A0A023Y6C3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

216778:DX03 RS10975
gene id: 216778:DX03_RS10975
uniprot id: A0A023Y3T8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KdsA family.
messages: Cytoplasm

216778:DX03 RS20120
gene id: 216778:DX03_RS20120
uniprot id: A0A023Y8N4
names: Function
names: Similarity
messages: Belongs to the RmuC family.
messages: Involved in DNA recombination.

216778:DX03 RS19065
gene id: 216778:DX03_RS19065
uniprot id: A0A023Y904
names: Similarity
messages: Belongs to the bacterial phospholipase C family.

216778:DX03 RS06280
gene id: 216778:DX03_RS06280
uniprot id: A0A023Y157
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Component of the RNA degradosome, which is a multiprotein complex involved in RNA processing and mRNA degradation.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

216778:DX03 RS07880
gene id: 216778:DX03_RS07880
uniprot id: A0A023Y1Y3
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

216778:DX03 RS10155
gene id: 216778:DX03_RS10155
uniprot id: A0A023Y3T7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of a number of rings mounted on a central rod.

216778:DX03 RS05965
gene id: 216778:DX03_RS05965
uniprot id: A0A023Y102
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

216778:DX03 RS13150
gene id: 216778:DX03_RS13150
uniprot id: A0A023Y5E3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DoxX family.
messages: Membrane

216778:DX03 RS12230
gene id: 216778:DX03_RS12230
uniprot id: A0A023Y4J1
names: Similarity
messages: Belongs to the pirin family.

216778:DX03 RS03200
gene id: 216778:DX03_RS03200
uniprot id: A0A023XZG2
names: Subcellular Location Annotation
messages: Membrane

216778:DX03 RS06120
gene id: 216778:DX03_RS06120
uniprot id: A0A023Y1T6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

216778:DX03 RS15710
gene id: 216778:DX03_RS15710
uniprot id: A0A023Y717
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

216778:DX03 RS15035
gene id: 216778:DX03_RS15035
uniprot id: A0A023Y6P2
names: Subcellular Location Annotation
messages: Membrane

216778:DX03 RS09740
gene id: 216778:DX03_RS09740
uniprot id: A0A023Y354
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

216778:DX03 RS06230
gene id: 216778:DX03_RS06230
uniprot id: A0A023Y1S2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Membrane

216778:DX03 RS07160
gene id: 216778:DX03_RS07160
uniprot id: A0A023Y213
names: Similarity
messages: Belongs to the CFA/CMAS family.

216778:DX03 RS12270
gene id: 216778:DX03_RS12270
uniprot id: A0A023Y552
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

216778:DX03 RS04750
gene id: 216778:DX03_RS04750
uniprot id: A0A023Y145
names: Similarity
messages: Belongs to the Dps family.

216778:DX03 RS03515
gene id: 216778:DX03_RS03515
uniprot id: A0A023Y008
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase group 1 family.
messages: Cell membrane
messages: Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP-Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A.

216778:DX03 RS08635
gene id: 216778:DX03_RS08635
uniprot id: A0A023Y293
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lactate permease family.
messages: Cell inner membrane
messages: Membrane
messages: Uptake of L-lactate across the membrane. Can also transport D-lactate and glycolate.

216778:DX03 RS15335
gene id: 216778:DX03_RS15335
uniprot id: A0A023Y6N0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Monomer.
messages: Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl-glutathione to form glutathione and D-lactic acid.

216778:DX03 RS17990
gene id: 216778:DX03_RS17990
uniprot id: A0A023Y8I8
names: Subcellular Location Annotation
messages: Membrane

216778:DX03 RS18190
gene id: 216778:DX03_RS18190
uniprot id: A0A023Y863
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

216778:DX03 RS07570
gene id: 216778:DX03_RS07570
uniprot id: A0A023Y2L8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.

216778:DX03 RS04795
gene id: 216778:DX03_RS04795
uniprot id: A0A023Y0D8
names: Similarity
messages: Belongs to the KAE1 / TsaD family. TsaB subfamily.

216778:DX03 RS05930
gene id: 216778:DX03_RS05930
uniprot id: A0A023Y1C3
names: Subcellular Location Annotation
messages: Membrane

216778:DX03 RS11820
gene id: 216778:DX03_RS11820
uniprot id: A0A023Y4V3
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

216778:DX03 RS04780
gene id: 216778:DX03_RS04780
uniprot id: A0A023Y113
names: Function
names: Similarity
messages: Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits).
messages: In the C-terminal section; belongs to the transpeptidase family.
messages: In the N-terminal section; belongs to the glycosyltransferase 51 family.

216778:DX03 RS06035
gene id: 216778:DX03_RS06035
uniprot id: A0A023Y0U2
names: Similarity
messages: Belongs to the SCO1/2 family.

216778:DX03 RS06205
gene id: 216778:DX03_RS06205
uniprot id: A0A023Y1R8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 1 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.

216778:DX03 RS11290
gene id: 216778:DX03_RS11290
uniprot id: A0A023Y4N8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

216778:DX03 RS10740
gene id: 216778:DX03_RS10740
uniprot id: A0A023Y3Q2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAD-like hydrolase superfamily. MasA/MtnC family.
messages: Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene).
messages: Binds 1 Mg(2+) ion per subunit.
messages: Monomer.

216778:DX03 RS19625
gene id: 216778:DX03_RS19625
uniprot id: A0A023Y8V9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FPG family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
messages: Monomer.

216778:DX03 RS14810
gene id: 216778:DX03_RS14810
uniprot id: A0A023Y6I9
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.

216778:DX03 RS03640
gene id: 216778:DX03_RS03640
uniprot id: A0A023Y0G1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

216778:DX03 RS01785
gene id: 216778:DX03_RS01785
uniprot id: A0A023XYN4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arsenical resistance-3 (ACR3) (TC 2.A.59) family.
messages: Cell membrane
messages: Membrane

216778:DX03 RS05400
gene id: 216778:DX03_RS05400
uniprot id: A0A023Y141
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

216778:DX03 RS00495
gene id: 216778:DX03_RS00495
uniprot id: A0A023XYN3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

216778:DX03 RS14590
gene id: 216778:DX03_RS14590
uniprot id: A0A023Y5J0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurD2 subfamily.
messages: Cell wall formation. Catalyzes the addition of L-glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

216778:DX03 RS15880
gene id: 216778:DX03_RS15880
uniprot id: A0A023Y791
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

216778:DX03 RS11710
gene id: 216778:DX03_RS11710
uniprot id: A0A023Y478
names: Similarity
messages: Belongs to the ribosome association toxin RatA family.

216778:DX03 RS15920
gene id: 216778:DX03_RS15920
uniprot id: A0A023Y6J5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

216778:DX03 RS15845
gene id: 216778:DX03_RS15845
uniprot id: A0A023Y6A2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

216778:DX03 RS18120
gene id: 216778:DX03_RS18120
uniprot id: A0A023Y7L0
names: Subcellular Location Annotation
messages: Membrane

216778:DX03 RS16180
gene id: 216778:DX03_RS16180
uniprot id: A0A023Y7D5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily.
messages: Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA.
messages: Cytoplasm
messages: Monomer.

216778:DX03 RS10410
gene id: 216778:DX03_RS10410
uniprot id: A0A023Y3B4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

216778:DX03 RS14985
gene id: 216778:DX03_RS14985
uniprot id: A0A023Y6M8
names: Similarity
messages: Belongs to the GSP E family.

216778:DX03 RS05390
gene id: 216778:DX03_RS05390
uniprot id: A0A023Y1H1
names: Similarity
messages: Belongs to the pirin family.

216778:DX03 RS17960
gene id: 216778:DX03_RS17960
uniprot id: A0A023Y7S2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COX11/CtaG family.
messages: Cell inner membrane
messages: Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I.

216778:DX03 RS08440
gene id: 216778:DX03_RS08440
uniprot id: A0A023Y2E4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

216778:DX03 RS15945
gene id: 216778:DX03_RS15945
uniprot id: A0A023Y6K0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

216778:DX03 RS08400
gene id: 216778:DX03_RS08400
uniprot id: A0A023Y2Z6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbC subfamily.
messages: Periplasm
messages: Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process.

216778:DX03 RS12370
gene id: 216778:DX03_RS12370
uniprot id: A0A023Y571
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruD family.
messages: Responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs.

216778:DX03 RS03830
gene id: 216778:DX03_RS03830
uniprot id: A0A023Y0G3
names: Similarity
messages: Belongs to the UPF0162 family.

216778:DX03 RS07905
gene id: 216778:DX03_RS07905
uniprot id: A0A023Y1Y7
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

216778:DX03 RS01645
gene id: 216778:DX03_RS01645
uniprot id: A0A023XZA1
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

216778:DX03 RS03520
gene id: 216778:DX03_RS03520
uniprot id: A0A023XZE9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Cell membrane
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

216778:DX03 RS16555
gene id: 216778:DX03_RS16555
uniprot id: A0A023Y7K3
names: Function
names: Similarity
messages: Belongs to the transpeptidase family. FtsI subfamily.
messages: Catalyzes cross-linking of the peptidoglycan cell wall at the division septum.

216778:DX03 RS09230
gene id: 216778:DX03_RS09230
uniprot id: A0A023Y3F2
names: Subcellular Location Annotation
messages: Membrane

216778:DX03 RS05275
gene id: 216778:DX03_RS05275
uniprot id: A0A023Y0G4
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

216778:DX03 RS19200
gene id: 216778:DX03_RS19200
uniprot id: A0A023Y8M4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecB family.
messages: Cytoplasm
messages: Homotetramer, a dimer of dimers. One homotetramer interacts with 1 SecA dimer.
messages: One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA.

216778:DX03 RS08335
gene id: 216778:DX03_RS08335
uniprot id: A0A023Y2Z1
names: Similarity
messages: Belongs to the SOS response-associated peptidase family.

216778:DX03 RS06810
gene id: 216778:DX03_RS06810
uniprot id: A0A023Y275
names: Subcellular Location Annotation
messages: Cytoplasm

216778:DX03 RS06345
gene id: 216778:DX03_RS06345
uniprot id: A0A023Y1K6
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

216778:DX03 RS14935
gene id: 216778:DX03_RS14935
uniprot id: A0A023Y6L6
names: Similarity
messages: Belongs to the UPF0301 (AlgH) family.

216778:DX03 RS14050
gene id: 216778:DX03_RS14050
uniprot id: A0A023Y5U9
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

216778:DX03 RS19610
gene id: 216778:DX03_RS19610
uniprot id: A0A023Y8K7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OpgD/OpgG family.
messages: Periplasm
messages: Probably involved in the control of the structural glucose backbone of osmoregulated periplasmic glucans (OPGs).

216778:DX03 RS19070
gene id: 216778:DX03_RS19070
uniprot id: A0A023Y8V2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

216778:DX03 RS07790
gene id: 216778:DX03_RS07790
uniprot id: A0A023Y2P9
names: Function
names: Subcellular Location Annotation
messages: Catalyzes the Claisen rearrangement of chorismate to prephenate and the decarboxylation/dehydration of prephenate to phenylpyruvate.
messages: Cytoplasm

216778:DX03 RS05375
gene id: 216778:DX03_RS05375
uniprot id: A0A023Y137
names: Similarity
messages: Belongs to the pirin family.

216778:DX03 RS11240
gene id: 216778:DX03_RS11240
uniprot id: A0A023Y4M8
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

216778:DX03 RS15805
gene id: 216778:DX03_RS15805
uniprot id: A0A023Y778
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

216778:DX03 RS11860
gene id: 216778:DX03_RS11860
uniprot id: A0A023Y4B1
names: Cofactor
names: Similarity
messages: Belongs to the DNA photolyase class-1 family.
messages: Belongs to the DNA photolyase family.
messages: Binds 1 FAD per subunit.

216778:DX03 RS05785
gene id: 216778:DX03_RS05785
uniprot id: A0A023Y0P7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

216778:DX03 RS14905
gene id: 216778:DX03_RS14905
uniprot id: A0A023Y6Q6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

216778:DX03 RS07350
gene id: 216778:DX03_RS07350
uniprot id: A0A023Y1V3
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.
messages: There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors.

216778:DX03 RS06250
gene id: 216778:DX03_RS06250
uniprot id: A0A023Y0X4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

216778:DX03 RS15540
gene id: 216778:DX03_RS15540
uniprot id: A0A023Y662
names: Subcellular Location Annotation
messages: Membrane

216778:DX03 RS09510
gene id: 216778:DX03_RS09510
uniprot id: A0A023Y3Q1
names: Similarity
messages: Belongs to the Gfa family.

216778:DX03 RS19995
gene id: 216778:DX03_RS19995
uniprot id: A0A023Y9D0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

216778:DX03 RS06325
gene id: 216778:DX03_RS06325
uniprot id: A0A023Y0Y9
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.

216778:DX03 RS04435
gene id: 216778:DX03_RS04435
uniprot id: A0A023Y0T9
names: Function
names: Similarity
messages: Belongs to the trehalose phosphatase family.
messages: Removes the phosphate from trehalose 6-phosphate to produce free trehalose.

216778:DX03 RS06675
gene id: 216778:DX03_RS06675
uniprot id: A0A023Y244
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

216778:DX03 RS09905
gene id: 216778:DX03_RS09905
uniprot id: A0A023Y3K9
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.

216778:DX03 RS06655
gene id: 216778:DX03_RS06655
uniprot id: A0A023Y1Z7
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

216778:DX03 RS04895
gene id: 216778:DX03_RS04895
uniprot id: A0A023Y0W8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

216778:DX03 RS15550
gene id: 216778:DX03_RS15550
uniprot id: A0A023Y739
names: Similarity
messages: Belongs to the folylpolyglutamate synthase family.

216778:DX03 RS04100
gene id: 216778:DX03_RS04100
uniprot id: A0A023Y0Q6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane
messages: Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

216778:DX03 RS08225
gene id: 216778:DX03_RS08225
uniprot id: A0A023Y313
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2).
messages: Homodimer.

216778:DX03 RS06335
gene id: 216778:DX03_RS06335
uniprot id: A0A023Y1X5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

216778:DX03 RS02965
gene id: 216778:DX03_RS02965
uniprot id: A0A023XZ51
names: Similarity
messages: Belongs to the UPF0250 family.

216778:DX03 RS11475
gene id: 216778:DX03_RS11475
uniprot id: A0A023Y4G7
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit B family.

216778:DX03 RS15720
gene id: 216778:DX03_RS15720
uniprot id: A0A4U3GG04
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

216778:DX03 RS18875
gene id: 216778:DX03_RS18875
uniprot id: A0A023Y8G2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

216778:DX03 RS12115
gene id: 216778:DX03_RS12115
uniprot id: A0A023Y562
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanD family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
messages: Cytoplasm
messages: Heterooctamer of four alpha and four beta subunits.
messages: Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus.

216778:DX03 RS13260
gene id: 216778:DX03_RS13260
uniprot id: A0A023Y5P6
names: Cofactor
names: Similarity
messages: Belongs to the peptidase S45 family.
messages: Binds 1 Ca(2+) ion per dimer.

216778:DX03 RS04425
gene id: 216778:DX03_RS04425
uniprot id: A0A023Y064
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyltransferase 20 family.
messages: Homotetramer.
messages: Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-alpha-D-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor.

216778:DX03 RS04335
gene id: 216778:DX03_RS04335
uniprot id: A0A023Y0R7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A24 family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Plays an essential role in type IV pili and type II pseudopili formation by proteolytically removing the leader sequence from substrate proteins and subsequently monomethylating the alpha-amino group of the newly exposed N-terminal phenylalanine.

216778:DX03 RS07735
gene id: 216778:DX03_RS07735
uniprot id: A0A023Y2T4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the urocanase family.
messages: Binds 1 NAD(+) per subunit.
messages: Catalyzes the conversion of urocanate to 4-imidazolone-5-propionate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

216778:DX03 RS15445
gene id: 216778:DX03_RS15445
uniprot id: A0A023Y6C7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

216778:DX03 RS12625
gene id: 216778:DX03_RS12625
uniprot id: A0A023Y5F1
names: Function
names: Similarity
messages: Belongs to the LpxK family.
messages: Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).

216778:DX03 RS05430
gene id: 216778:DX03_RS05430
uniprot id: A0A023Y0I7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

216778:DX03 RS13985
gene id: 216778:DX03_RS13985
uniprot id: A0A023Y5F6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

216778:DX03 RS19780
gene id: 216778:DX03_RS19780
uniprot id: A0A023Y8P9
names: Similarity
messages: Belongs to the PhzF family.

216778:DX03 RS10795
gene id: 216778:DX03_RS10795
uniprot id: A0A4U3GNF6
names: Caution
names: Similarity
messages: Belongs to the bacterial glucokinase family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

216778:DX03 RS00095
gene id: 216778:DX03_RS00095
uniprot id: A0A023XYF9
names: Function
names: PTM
names: Similarity
messages: Acetylated. Deacetylation by the SIR2-homolog deacetylase activates the enzyme.
messages: Belongs to the ATP-dependent AMP-binding enzyme family.
messages: Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.

216778:DX03 RS18910
gene id: 216778:DX03_RS18910
uniprot id: A0A023Y862
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

216778:DX03 RS03720
gene id: 216778:DX03_RS03720
uniprot id: A0A023XZQ6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the H(+)-translocating pyrophosphatase (TC 3.A.10) family. K(+)-insensitive subfamily.
messages: Cell membrane
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force.

216778:DX03 RS03155
gene id: 216778:DX03_RS03155
uniprot id: A0A023Y077
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

216778:DX03 RS04195
gene id: 216778:DX03_RS04195
uniprot id: A0A023Y011
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

216778:DX03 RS19605
gene id: 216778:DX03_RS19605
uniprot id: A0A023Y8B6
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidine kinase family.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

216778:DX03 RS00680
gene id: 216778:DX03_RS00680
uniprot id: A0A023XXW1
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the shikimate dehydrogenase family.
messages: Homodimer.
messages: Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

216778:DX03 RS11635
gene id: 216778:DX03_RS11635
uniprot id: A0A023Y459
names: Subcellular Location Annotation
messages: Membrane

216778:DX03 RS10830
gene id: 216778:DX03_RS10830
uniprot id: A0A023Y436
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

216778:DX03 RS19565
gene id: 216778:DX03_RS19565
uniprot id: A0A023Y9A6
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPAT/DAPAT family.
messages: Cell membrane
messages: The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate.

216778:DX03 RS02730
gene id: 216778:DX03_RS02730
uniprot id: A0A023XZX4
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

216778:DX03 RS06355
gene id: 216778:DX03_RS06355
uniprot id: A0A023Y172
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial histone-like protein family.
messages: Heterodimer of an alpha and a beta chain.
messages: This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.

216778:DX03 RS15175
gene id: 216778:DX03_RS15175
uniprot id: A0A023Y604
names: Similarity
messages: Belongs to the fabD family.

216778:DX03 RS14860
gene id: 216778:DX03_RS14860
uniprot id: A0A023Y6J9
names: Function
names: Similarity
messages: Belongs to the ABC transporter superfamily. Outer membrane lipopolysaccharide export (TC 1.B.42) family.
messages: Part of the ABC transporter complex LptBFG involved in the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane. Probably responsible for energy coupling to the transport system.

216778:DX03 RS19385
gene id: 216778:DX03_RS19385
uniprot id: A0A023Y8F3
names: Similarity
messages: Belongs to the pyruvate:ferredoxin/flavodoxin oxidoreductase family.

216778:DX03 RS00280
gene id: 216778:DX03_RS00280
uniprot id: A0A023XXN9
names: Similarity
messages: Belongs to the universal stress protein A family.

216778:DX03 RS14655
gene id: 216778:DX03_RS14655
uniprot id: A0A023Y6F6
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

216778:DX03 RS05470
gene id: 216778:DX03_RS05470
uniprot id: A0A023Y1E3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 3 family. NagZ subfamily.
messages: Cytoplasm
messages: Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide-linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N-acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides.

216778:DX03 RS10505
gene id: 216778:DX03_RS10505
uniprot id: A0A023Y3Y5
names: Function
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.
messages: Catalyzes the isomerization of citrate to isocitrate via cis-aconitate.

216778:DX03 RS11560
gene id: 216778:DX03_RS11560
uniprot id: A0A023Y443
names: Subcellular Location Annotation
messages: Membrane

216778:DX03 RS03285
gene id: 216778:DX03_RS03285
uniprot id: A0A023Y067
names: Similarity
messages: Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family.

216778:DX03 RS12075
gene id: 216778:DX03_RS12075
uniprot id: A0A023Y4T5
names: Similarity
messages: Belongs to the KHG/KDPG aldolase family.

216778:DX03 RS07050
gene id: 216778:DX03_RS07050
uniprot id: A0A023Y1Z2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

216778:DX03 RS08290
gene id: 216778:DX03_RS08290
uniprot id: A0A023Y246
names: Subcellular Location Annotation
messages: Membrane

216778:DX03 RS14235
gene id: 216778:DX03_RS14235
uniprot id: A0A023Y5C2
names: Similarity
messages: Belongs to the MQO family.

216778:DX03 RS02880
gene id: 216778:DX03_RS02880
uniprot id: A0A023XZZ9
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2).

216778:DX03 RS01405
gene id: 216778:DX03_RS01405
uniprot id: A0A023XZ68
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Homodimer.

216778:DX03 RS01890
gene id: 216778:DX03_RS01890
uniprot id: A0A023XZG7
names: Cofactor
names: Similarity
messages: Belongs to the carotenoid oxygenase family.
messages: Binds 1 Fe(2+) ion per subunit.

216778:DX03 RS18110
gene id: 216778:DX03_RS18110
uniprot id: A0A023Y8E0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IA subfamily.
messages: Cell membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system and for the release of the potassium ions to the cytoplasm.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

216778:DX03 RS11850
gene id: 216778:DX03_RS11850
uniprot id: A0A023Y4N6
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

216778:DX03 RS14345
gene id: 216778:DX03_RS14345
uniprot id: A0A023Y6D2
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

216778:DX03 RS07975
gene id: 216778:DX03_RS07975
uniprot id: A0A023Y2I3
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

216778:DX03 RS11965
gene id: 216778:DX03_RS11965
uniprot id: A0A023Y532
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

216778:DX03 RS14020
gene id: 216778:DX03_RS14020
uniprot id: A0A023Y626
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

216778:DX03 RS12155
gene id: 216778:DX03_RS12155
uniprot id: A0A023Y4V0
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

216778:DX03 RS14690
gene id: 216778:DX03_RS14690
uniprot id: A0A023Y5L3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

216778:DX03 RS10825
gene id: 216778:DX03_RS10825
uniprot id: A0A023Y4C1
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the C-terminal section; belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: In the N-terminal section; belongs to the histidinol-phosphatase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

216778:DX03 RS00145
gene id: 216778:DX03_RS00145
uniprot id: A0A4U3GL93
names: Caution
names: Function
names: Similarity
messages: Belongs to the ParB family.
messages: Involved in chromosome partition. Localize to both poles of the predivisional cell following completion of DNA replication. Binds to the DNA origin of replication.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

216778:DX03 RS00055
gene id: 216778:DX03_RS00055
uniprot id: A0A023XXL0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

216778:DX03 RS17335
gene id: 216778:DX03_RS17335
uniprot id: A0A023Y7B9
names: Similarity
messages: Belongs to the MotB family.

216778:DX03 RS06805
gene id: 216778:DX03_RS06805
uniprot id: A0A023Y1H6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M20A family. N-acetylcitrulline deacetylase subfamily.
messages: Binds 1 Co(2+) ion per subunit.
messages: Catalyzes the deacetylation of N-acetyl-L-citrulline to produce L-citrulline. This is a step in an alternative arginine biosynthesis pathway.

216778:DX03 RS01635
gene id: 216778:DX03_RS01635
uniprot id: A0A023XYK3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Homodimer. Forms a membrane-associated complex with FtsX.
messages: Part of the ABC transporter FtsEX involved in cellular division. Important for assembly or stability of the septal ring.

216778:DX03 RS03925
gene id: 216778:DX03_RS03925
uniprot id: A0A023Y0L7
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

216778:DX03 RS10255
gene id: 216778:DX03_RS10255
uniprot id: A0A023Y3V3
names: Function
names: Similarity
messages: Belongs to the sigma-54 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

216778:DX03 RS13710
gene id: 216778:DX03_RS13710
uniprot id: A0A023Y614
names: Similarity
messages: Belongs to the peptidase M13 family.

216778:DX03 RS10010
gene id: 216778:DX03_RS10010
uniprot id: A0A023Y327
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LolA family.
messages: Monomer.
messages: Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane).
messages: Periplasm

216778:DX03 RS13190
gene id: 216778:DX03_RS13190
uniprot id: A0A023Y5T6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. RlmB subfamily.
messages: Cytoplasm
messages: Specifically methylates the ribose of guanosine 2251 in 23S rRNA.

216778:DX03 RS13290
gene id: 216778:DX03_RS13290
uniprot id: A0A023Y5G0
names: Similarity
messages: Belongs to the ArsC family.

216778:DX03 RS05450
gene id: 216778:DX03_RS05450
uniprot id: A0A023Y147
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. RlmD subfamily.
messages: Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA.

216778:DX03 RS00050
gene id: 216778:DX03_RS00050
uniprot id: A0A023XY49
names: Similarity
messages: Belongs to the GSP E family.

216778:DX03 RS02800
gene id: 216778:DX03_RS02800
uniprot id: A0A023Y016
names: Subcellular Location Annotation
messages: Cell inner membrane

216778:DX03 RS01005
gene id: 216778:DX03_RS01005
uniprot id: A0A023XYW9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

216778:DX03 RS03930
gene id: 216778:DX03_RS03930
uniprot id: A0A023Y0I1
names: Similarity
messages: Belongs to the RutC family.

216778:DX03 RS10805
gene id: 216778:DX03_RS10805
uniprot id: A0A023Y431
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the C-terminal section; belongs to the PRA-PH family.
messages: In the N-terminal section; belongs to the PRA-CH family.

216778:DX03 RS06695
gene id: 216778:DX03_RS06695
uniprot id: A0A023Y1F1
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

216778:DX03 RS12620
gene id: 216778:DX03_RS12620
uniprot id: A0A023Y5J4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
messages: Belongs to the KdsB family.
messages: Cytoplasm

216778:DX03 RS04245
gene id: 216778:DX03_RS04245
uniprot id: A0A023Y023
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscL family.
messages: Cell inner membrane
messages: Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
messages: Homopentamer.
messages: Membrane

216778:DX03 RS07025
gene id: 216778:DX03_RS07025
uniprot id: A0A023Y1Y6
names: Similarity
messages: Belongs to the BolA/IbaG family.

216778:DX03 RS00930
gene id: 216778:DX03_RS00930
uniprot id: A0A023XYJ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

216778:DX03 RS02660
gene id: 216778:DX03_RS02660
uniprot id: A0A023XZL6
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

216778:DX03 RS13365
gene id: 216778:DX03_RS13365
uniprot id: A0A023Y4X5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with (2E,6E)-farnesyl diphosphate (E,E-FPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E,38E)-undecaprenyl diphosphate (di-trans,octa-cis-UPP). UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide.
messages: Homodimer.

216778:DX03 RS14065
gene id: 216778:DX03_RS14065
uniprot id: A0A023Y676
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

216778:DX03 RS15650
gene id: 216778:DX03_RS15650
uniprot id: A0A023Y755
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

216778:DX03 RS16515
gene id: 216778:DX03_RS16515
uniprot id: A0A023Y765
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsQ/DivIB family. FtsQ subfamily.
messages: Cell inner membrane
messages: Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly.
messages: Part of a complex composed of FtsB, FtsL and FtsQ.

216778:DX03 RS19775
gene id: 216778:DX03_RS19775
uniprot id: A0A023Y8F4
names: Similarity
messages: Belongs to the cysteine dioxygenase family.

216778:DX03 RS09505
gene id: 216778:DX03_RS09505
uniprot id: A0A023Y307
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S33 family.
messages: Cytoplasm

216778:DX03 RS06155
gene id: 216778:DX03_RS06155
uniprot id: A0A023Y1H2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

216778:DX03 RS09790
gene id: 216778:DX03_RS09790
uniprot id: A0A023Y364
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

216778:DX03 RS17190
gene id: 216778:DX03_RS17190
uniprot id: A0A023Y7Z1
names: Subcellular Location Annotation
messages: Membrane

216778:DX03 RS10730
gene id: 216778:DX03_RS10730
uniprot id: A0A023Y419
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the aldolase class II family. MtnB subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P).

216778:DX03 RS11590
gene id: 216778:DX03_RS11590
uniprot id: A0A023Y4U7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YajC family.
messages: Cell inner membrane
messages: Membrane

216778:DX03 RS10720
gene id: 216778:DX03_RS10720
uniprot id: A0A023Y4E5
names: Subcellular Location Annotation
messages: Membrane

216778:DX03 RS01095
gene id: 216778:DX03_RS01095
uniprot id: A0A023XY98
names: Similarity
messages: Belongs to the P(II) protein family.

216778:DX03 RS16650
gene id: 216778:DX03_RS16650
uniprot id: A0A023Y6W8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DHBP synthase family.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Homodimer.
messages: In the C-terminal section; belongs to the GTP cyclohydrolase II family.
messages: In the N-terminal section; belongs to the DHBP synthase family.

216778:DX03 RS07825
gene id: 216778:DX03_RS07825
uniprot id: A0A4U3GSW9
names: Caution
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

216778:DX03 RS04985
gene id: 216778:DX03_RS04985
uniprot id: A0A023Y1B1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
messages: Cytoplasm
messages: Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.

216778:DX03 RS05415
gene id: 216778:DX03_RS05415
uniprot id: A0A023Y1H5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

216778:DX03 RS07615
gene id: 216778:DX03_RS07615
uniprot id: A0A023Y2R5
names: Similarity
messages: Belongs to the bacterial PQQ dehydrogenase family.

216778:DX03 RS01650
gene id: 216778:DX03_RS01650
uniprot id: A0A023XYY9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
messages: Cytoplasm
messages: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.

216778:DX03 RS16565
gene id: 216778:DX03_RS16565
uniprot id: A0A023Y775
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

216778:DX03 RS15680
gene id: 216778:DX03_RS15680
uniprot id: A0A023Y759
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

216778:DX03 RS01160
gene id: 216778:DX03_RS01160
uniprot id: A0A023XYN9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the calycin superfamily. Lipocalin family.
messages: Cell outer membrane
messages: Homodimer.
messages: Involved in the storage or transport of lipids necessary for membrane maintenance under stressful conditions. Displays a binding preference for lysophospholipids.

216778:DX03 RS15465
gene id: 216778:DX03_RS15465
uniprot id: A0A023Y651
names: Function
names: Similarity
messages: Belongs to the glutaredoxin family.
messages: Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins.

216778:DX03 RS15400
gene id: 216778:DX03_RS15400
uniprot id: A0A023Y720
names: Subcellular Location Annotation
messages: Membrane

216778:DX03 RS18380
gene id: 216778:DX03_RS18380
uniprot id: A0A023Y8P7
names: Similarity
messages: Belongs to the peptidase M17 family.

216778:DX03 RS18105
gene id: 216778:DX03_RS18105
uniprot id: A0A023Y8K2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KdpA family.
messages: Cell membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds the extracellular potassium ions and delivers the ions to the membrane domain of KdpB through an intramembrane tunnel.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

216778:DX03 RS08510
gene id: 216778:DX03_RS08510
uniprot id: A0A023Y272
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

216778:DX03 RS20010
gene id: 216778:DX03_RS20010
uniprot id: A0A023Y8U8
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

216778:DX03 RS05990
gene id: 216778:DX03_RS05990
uniprot id: A0A023Y106
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

216778:DX03 RS16800
gene id: 216778:DX03_RS16800
uniprot id: A0A023Y6S0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial secretin family. GSP D subfamily.
messages: Cell outer membrane
messages: Membrane

216778:DX03 RS16210
gene id: 216778:DX03_RS16210
uniprot id: A0A023Y7A4
names: Similarity
messages: Belongs to the histone deacetylase family.

216778:DX03 RS09185
gene id: 216778:DX03_RS09185
uniprot id: A0A4U3GP55
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Cytochrome bo(3) ubiquinol terminal oxidase is the component of the aerobic respiratory chain of E.coli that predominates when cells are grown at high aeration. Has proton pump activity across the membrane in addition to electron transfer, pumping 2 protons/electron.
messages: Heterooctamer of two A chains, two B chains, two C chains and two D chains.
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

216778:DX03 RS07550
gene id: 216778:DX03_RS07550
uniprot id: A0A023Y1T5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein bS6.

216778:DX03 RS10475
gene id: 216778:DX03_RS10475
uniprot id: A0A023Y466
names: Function
messages: Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP.

216778:DX03 RS06975
gene id: 216778:DX03_RS06975
uniprot id: A0A023Y1X7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmC/CycZ/HelC family.
messages: Cell inner membrane
messages: Membrane
messages: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.

216778:DX03 RS18060
gene id: 216778:DX03_RS18060
uniprot id: A0A023Y8D5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 2 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

216778:DX03 RS06980
gene id: 216778:DX03_RS06980
uniprot id: A0A023Y1D4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmB/CycW/HelB family.
messages: Cell inner membrane
messages: Membrane
messages: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.

216778:DX03 RS02570
gene id: 216778:DX03_RS02570
uniprot id: A0A023XZ65
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Membrane

216778:DX03 RS02930
gene id: 216778:DX03_RS02930
uniprot id: A0A023Y010
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transpeptidase family. MrdA subfamily.
messages: Catalyzes cross-linking of the peptidoglycan cell wall.
messages: Cell inner membrane

216778:DX03 RS11430
gene id: 216778:DX03_RS11430
uniprot id: A0A023Y3S4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

216778:DX03 RS05485
gene id: 216778:DX03_RS05485
uniprot id: A0A023Y0S6
names: Subcellular Location Annotation
messages: Cytoplasm

216778:DX03 RS02520
gene id: 216778:DX03_RS02520
uniprot id: A0A023XZ56
names: Activity Regulation
names: Caution
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Inhibited by fructose 1,6-bisphosphate (FBP).
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

216778:DX03 RS18725
gene id: 216778:DX03_RS18725
uniprot id: A0A023Y8D9
names: Function
names: Similarity
messages: Belongs to the PurU family.
messages: Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).

216778:DX03 RS17300
gene id: 216778:DX03_RS17300
uniprot id: A0A023Y7M3
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

216778:DX03 RS15730
gene id: 216778:DX03_RS15730
uniprot id: A0A023Y766
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

216778:DX03 RS12310
gene id: 216778:DX03_RS12310
uniprot id: A0A023Y4K7
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

216778:DX03 RS13785
gene id: 216778:DX03_RS13785
uniprot id: A0A023Y625
names: Similarity
messages: Belongs to the barstar family.

216778:DX03 RS17480
gene id: 216778:DX03_RS17480
uniprot id: A0A023Y777
names: Subcellular Location Annotation
messages: Membrane

216778:DX03 RS15560
gene id: 216778:DX03_RS15560
uniprot id: A0A023Y6Q7
names: Function
names: Similarity
messages: Belongs to the peptidase S46 family.
messages: Catalyzes the removal of dipeptides from the N-terminus of oligopeptides.

216778:DX03 RS17155
gene id: 216778:DX03_RS17155
uniprot id: A0A023Y6Z2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

216778:DX03 RS06555
gene id: 216778:DX03_RS06555
uniprot id: A0A023Y1Y1
names: Subcellular Location Annotation
messages: Membrane

216778:DX03 RS14600
gene id: 216778:DX03_RS14600
uniprot id: A0A023Y6I7
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family.

216778:DX03 RS11245
gene id: 216778:DX03_RS11245
uniprot id: A0A023Y4J4
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

216778:DX03 RS19660
gene id: 216778:DX03_RS19660
uniprot id: A0A023Y8L9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class A bacterial acid phosphatase family.
messages: Periplasm

216778:DX03 RS15015
gene id: 216778:DX03_RS15015
uniprot id: A0A023Y6E9
names: Subcellular Location Annotation
messages: Membrane

216778:DX03 RS10650
gene id: 216778:DX03_RS10650
uniprot id: A0A023Y492
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

216778:DX03 RS12400
gene id: 216778:DX03_RS12400
uniprot id: A0A023Y507
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

216778:DX03 RS10385
gene id: 216778:DX03_RS10385
uniprot id: A0A023Y3B1
names: Similarity
messages: Belongs to the ParA family. MinD subfamily.

216778:DX03 RS04880
gene id: 216778:DX03_RS04880
uniprot id: A0A023Y0H0
names: Similarity
messages: Belongs to the band 7/mec-2 family.

216778:DX03 RS05760
gene id: 216778:DX03_RS05760
uniprot id: A0A023Y0W7
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

216778:DX03 RS04210
gene id: 216778:DX03_RS04210
uniprot id: A0A023Y0E9
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

216778:DX03 RS15860
gene id: 216778:DX03_RS15860
uniprot id: A0A023Y743
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

216778:DX03 RS00760
gene id: 216778:DX03_RS00760
uniprot id: A0A023XY39
names: Subcellular Location Annotation
messages: Membrane

216778:DX03 RS19220
gene id: 216778:DX03_RS19220
uniprot id: A0A023Y8X8
names: Function
names: Similarity
messages: Belongs to the uroporphyrinogen-III synthase family.
messages: Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.

216778:DX03 RS15800
gene id: 216778:DX03_RS15800
uniprot id: A0A023Y6I1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

216778:DX03 RS03850
gene id: 216778:DX03_RS03850
uniprot id: A0A023Y0K0
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

216778:DX03 RS18070
gene id: 216778:DX03_RS18070
uniprot id: A0A023Y7K4
names: Function
names: Similarity
messages: Belongs to the anhydro-N-acetylmuramic acid kinase family.
messages: Catalyzes the specific phosphorylation of 1,6-anhydro-N-acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling.

216778:DX03 RS18525
gene id: 216778:DX03_RS18525
uniprot id: A0A023Y8A5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

216778:DX03 RS02905
gene id: 216778:DX03_RS02905
uniprot id: A0A023Y004
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

216778:DX03 RS06890
gene id: 216778:DX03_RS06890
uniprot id: A0A023Y1J5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Cell inner membrane
messages: Membrane

216778:DX03 RS14950
gene id: 216778:DX03_RS14950
uniprot id: A0A023Y616
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

216778:DX03 RS11090
gene id: 216778:DX03_RS11090
uniprot id: A0A023Y491
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

216778:DX03 RS16320
gene id: 216778:DX03_RS16320
uniprot id: A0A023Y6I2
names: Subcellular Location Annotation
messages: Membrane

216778:DX03 RS09330
gene id: 216778:DX03_RS09330
uniprot id: A0A023Y3L2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

216778:DX03 RS09495
gene id: 216778:DX03_RS09495
uniprot id: A0A023Y3B5
names: Similarity
messages: Belongs to the DNA glycosylase MPG family.

216778:DX03 RS07020
gene id: 216778:DX03_RS07020
uniprot id: A0A023Y277
names: Similarity
messages: Belongs to the YciI family.

216778:DX03 RS11605
gene id: 216778:DX03_RS11605
uniprot id: A0A023Y3W1
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

216778:DX03 RS06255
gene id: 216778:DX03_RS06255
uniprot id: A0A023Y152
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

216778:DX03 RS05535
gene id: 216778:DX03_RS05535
uniprot id: A0A023Y0T5
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

216778:DX03 RS04275
gene id: 216778:DX03_RS04275
uniprot id: A0A023Y0U7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ThiG family.
messages: Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
messages: Cytoplasm
messages: Homotetramer. Forms heterodimers with either ThiH or ThiS.

216778:DX03 RS00430
gene id: 216778:DX03_RS00430
uniprot id: A0A023XXR5
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

216778:DX03 RS16255
gene id: 216778:DX03_RS16255
uniprot id: A0A023Y7E9
names: Function
names: Similarity
messages: Belongs to the dihydrofolate reductase family.
messages: Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.

216778:DX03 RS19700
gene id: 216778:DX03_RS19700
uniprot id: A0A023Y8D7
names: Similarity
messages: Belongs to the biopterin-dependent aromatic amino acid hydroxylase family.

216778:DX03 RS04980
gene id: 216778:DX03_RS04980
uniprot id: A0A023Y0J8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0073 (Hly-III) family.
messages: Membrane

216778:DX03 RS01415
gene id: 216778:DX03_RS01415
uniprot id: A0A023XYU0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COQ7 family.
messages: Binds 2 iron ions per subunit.
messages: Catalyzes the hydroxylation of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol during ubiquinone biosynthesis.
messages: Cell membrane

216778:DX03 RS13900
gene id: 216778:DX03_RS13900
uniprot id: A0A023Y564
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

216778:DX03 RS11230
gene id: 216778:DX03_RS11230
uniprot id: A0A023Y3P2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

216778:DX03 RS04800
gene id: 216778:DX03_RS04800
uniprot id: A0A023Y155
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

216778:DX03 RS06210
gene id: 216778:DX03_RS06210
uniprot id: A0A023Y1I1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 23 kDa subunit family.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

216778:DX03 RS20485
gene id: 216778:DX03_RS20485
uniprot id: A0A023Y8G7
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Homododecamer.

216778:DX03 RS20005
gene id: 216778:DX03_RS20005
uniprot id: A0A023Y8K8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

216778:DX03 RS13920
gene id: 216778:DX03_RS13920
uniprot id: A0A023Y5S5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Membrane
messages: The cytochrome bo(3) ubiquinol oxidase complex is a heterooctamer of two A chains, two B chains, two C chains and two D chains.

216778:DX03 RS05980
gene id: 216778:DX03_RS05980
uniprot id: A0A023Y1D3
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dCTP deaminase family.
messages: Catalyzes the deamination of dCTP to dUTP.
messages: Homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

216778:DX03 RS00855
gene id: 216778:DX03_RS00855
uniprot id: A0A023XYH7
names: Cofactor
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. NagA family.
messages: Binds 1 divalent metal cation per subunit.

216778:DX03 RS02495
gene id: 216778:DX03_RS02495
uniprot id: A0A023XZ53
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HMBS family.
messages: Binds 1 dipyrromethane group covalently.
messages: Monomer.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
messages: The porphobilinogen subunits are added to the dipyrromethane group.

216778:DX03 RS07085
gene id: 216778:DX03_RS07085
uniprot id: A0A023Y1G1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZIP transporter (TC 2.A.5) family. ZupT subfamily.
messages: Cell membrane
messages: Mediates zinc uptake. May also transport other divalent cations.
messages: Membrane

216778:DX03 RS01115
gene id: 216778:DX03_RS01115
uniprot id: A0A023XY30
names: Function
names: Similarity
names: Subunit
messages: Belongs to the spermidine/spermine synthase family.
messages: Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
messages: Homodimer or homotetramer.

216778:DX03 RS03425
gene id: 216778:DX03_RS03425
uniprot id: A0A023XZK5
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

216778:DX03 RS00195
gene id: 216778:DX03_RS00195
uniprot id: A0A023XYH9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

216778:DX03 RS05435
gene id: 216778:DX03_RS05435
uniprot id: A0A023Y0R9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer.

216778:DX03 RS16595
gene id: 216778:DX03_RS16595
uniprot id: A0A023Y6N1
names: Similarity
messages: Belongs to the UPF0102 family.

216778:DX03 RS12860
gene id: 216778:DX03_RS12860
uniprot id: A0A023Y5I1
names: Similarity
messages: Belongs to the PhoH family.

216778:DX03 RS10080
gene id: 216778:DX03_RS10080
uniprot id: A0A023Y3S6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

216778:DX03 RS17010
gene id: 216778:DX03_RS17010
uniprot id: A0A023Y745
names: Similarity
messages: Belongs to the phosphohexose mutase family.

216778:DX03 RS09685
gene id: 216778:DX03_RS09685
uniprot id: A0A023Y2U9
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

216778:DX03 RS12275
gene id: 216778:DX03_RS12275
uniprot id: A0A023Y4X4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecX family.
messages: Cytoplasm
messages: Modulates RecA activity.

216778:DX03 RS09405
gene id: 216778:DX03_RS09405
uniprot id: A0A023Y3N0
names: Subcellular Location Annotation
messages: Membrane

216778:DX03 RS11435
gene id: 216778:DX03_RS11435
uniprot id: A0A023Y418
names: Similarity
messages: Belongs to the bacterial PQQ dehydrogenase family.

216778:DX03 RS00850
gene id: 216778:DX03_RS00850
uniprot id: A0A023XYU2
names: Subcellular Location Annotation
messages: Membrane

216778:DX03 RS15765
gene id: 216778:DX03_RS15765
uniprot id: A0A023Y6T2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

216778:DX03 RS18775
gene id: 216778:DX03_RS18775
uniprot id: A0A023Y8E6
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

216778:DX03 RS18585
gene id: 216778:DX03_RS18585
uniprot id: A0A023Y805
names: Similarity
messages: Belongs to the HIBADH-related family.

216778:DX03 RS10400
gene id: 216778:DX03_RS10400
uniprot id: A0A023Y454
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CheZ family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P).

216778:DX03 RS04565
gene id: 216778:DX03_RS04565
uniprot id: A0A023Y090
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp).
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

216778:DX03 RS09190
gene id: 216778:DX03_RS09190
uniprot id: A0A023Y2J3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome c oxidase bacterial subunit 4 family.
messages: Cytochrome bo(3) ubiquinol terminal oxidase is the component of the aerobic respiratory chain of E.coli that predominates when cells are grown at high aeration. Has proton pump activity across the membrane in addition to electron transfer, pumping 2 protons/electron.
messages: Heterooctamer of two A chains, two B chains, two C chains and two D chains.
messages: Membrane

216778:DX03 RS09105
gene id: 216778:DX03_RS09105
uniprot id: A0A023Y336
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

216778:DX03 RS18430
gene id: 216778:DX03_RS18430
uniprot id: A0A023Y8Q5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

216778:DX03 RS15675
gene id: 216778:DX03_RS15675
uniprot id: A0A023Y6G0
names: Cofactor
names: Similarity
messages: Belongs to the class-II DAHP synthase family.
messages: Binds 1 divalent cation per subunit. The enzyme is active with manganese, cobalt or cadmium ions.

216778:DX03 RS04135
gene id: 216778:DX03_RS04135
uniprot id: A0A023Y0D1
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

216778:DX03 RS13850
gene id: 216778:DX03_RS13850
uniprot id: A0A023Y555
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein uS19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein uS19.

216778:DX03 RS05780
gene id: 216778:DX03_RS05780
uniprot id: A0A023Y195
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

216778:DX03 RS09400
gene id: 216778:DX03_RS09400
uniprot id: A0A023Y2Y5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

216778:DX03 RS17370
gene id: 216778:DX03_RS17370
uniprot id: A0A023Y7Y3
names: Similarity
messages: Belongs to the DODA-type extradiol aromatic ring-opening dioxygenase family.

216778:DX03 RS00465
gene id: 216778:DX03_RS00465
uniprot id: A0A023XYQ4
names: Similarity
messages: Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family.

216778:DX03 RS06850
gene id: 216778:DX03_RS06850
uniprot id: A0A023Y198
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family.
messages: Cell membrane
messages: Membrane

216778:DX03 RS06785
gene id: 216778:DX03_RS06785
uniprot id: A0A023Y267
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

216778:DX03 RS13550
gene id: 216778:DX03_RS13550
uniprot id: A0A023Y5Z3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DEAD box helicase family. DeaD/CsdA subfamily.
messages: Cytoplasm
messages: DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation.

216778:DX03 RS08545
gene id: 216778:DX03_RS08545
uniprot id: A0A023Y356
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-C family. DnaE2 subfamily.
messages: Cytoplasm
messages: DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase.