216142:LT40 RS03935
gene id: 216142:LT40_RS03935
uniprot id: A0A089YSD8
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

216142:LT40 RS15375
gene id: 216142:LT40_RS15375
uniprot id: A0A089YZ13
names: Subcellular Location Annotation
messages: Membrane

216142:LT40 RS17915
gene id: 216142:LT40_RS17915
uniprot id: A0A089YUC6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the etk/wzc family.
messages: Cell inner membrane
messages: Membrane

216142:LT40 RS12080
gene id: 216142:LT40_RS12080
uniprot id: A0A089ZQS2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family. QueF type 2 subfamily.
messages: Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
messages: Cytoplasm
messages: Homodimer.

216142:LT40 RS00280
gene id: 216142:LT40_RS00280
uniprot id: A0A089ZPI1
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

216142:LT40 RS11145
gene id: 216142:LT40_RS11145
uniprot id: A0A089YW52
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

216142:LT40 RS18580
gene id: 216142:LT40_RS18580
uniprot id: A0A089YSD5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DHBP synthase family.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Homodimer.
messages: In the C-terminal section; belongs to the GTP cyclohydrolase II family.
messages: In the N-terminal section; belongs to the DHBP synthase family.

216142:LT40 RS16105
gene id: 216142:LT40_RS16105
uniprot id: A0A089YTF0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0). The b'-subunit is a diverged and duplicated form of b found in plants and photosynthetic bacteria.
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

216142:LT40 RS05240
gene id: 216142:LT40_RS05240
uniprot id: A0A089YR55
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane

216142:LT40 RS09375
gene id: 216142:LT40_RS09375
uniprot id: A0A089YPT2
names: Similarity
messages: Belongs to the UDPGP type 2 family.

216142:LT40 RS15575
gene id: 216142:LT40_RS15575
uniprot id: A0A089YT07
names: Similarity
messages: Belongs to the acetyl-CoA hydrolase/transferase family.

216142:LT40 RS03580
gene id: 216142:LT40_RS03580
uniprot id: A0A089YLU7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Cytoplasm
messages: Homodimer.

216142:LT40 RS11525
gene id: 216142:LT40_RS11525
uniprot id: A0A089YQY9
names: Subcellular Location Annotation
messages: Membrane

216142:LT40 RS03330
gene id: 216142:LT40_RS03330
uniprot id: A0A089ZPU5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome c oxidase bacterial subunit 4 family.
messages: Cytochrome bo(3) ubiquinol terminal oxidase is the component of the aerobic respiratory chain of E.coli that predominates when cells are grown at high aeration. Has proton pump activity across the membrane in addition to electron transfer, pumping 2 protons/electron.
messages: Heterooctamer of two A chains, two B chains, two C chains and two D chains.
messages: Membrane

216142:LT40 RS00515
gene id: 216142:LT40_RS00515
uniprot id: A0A089YNR3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsB family.
messages: Cell inner membrane
messages: Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.
messages: Part of a complex composed of FtsB, FtsL and FtsQ.

216142:LT40 RS01180
gene id: 216142:LT40_RS01180
uniprot id: A0A089YKG9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 independent methionine synthase family.
messages: Binds 1 zinc ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine resulting in methionine formation.

216142:LT40 RS04970
gene id: 216142:LT40_RS04970
uniprot id: A0A089YSZ4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ExbD/TolR family.
messages: Cell inner membrane
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

216142:LT40 RS15710
gene id: 216142:LT40_RS15710
uniprot id: A0A089ZR56
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 9 family.
messages: Periplasm

216142:LT40 RS12300
gene id: 216142:LT40_RS12300
uniprot id: A0A089YUS4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily.
messages: Catalyzes the hydrolysis of 5-hydroxyisourate (HIU) to 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU).
messages: Homotetramer.

216142:LT40 RS04155
gene id: 216142:LT40_RS04155
uniprot id: A0A089YQG9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

216142:LT40 RS03060
gene id: 216142:LT40_RS03060
uniprot id: A0A089YJA1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DEAD box helicase family. RhlB subfamily.
messages: Component of the RNA degradosome, which is a multiprotein complex involved in RNA processing and mRNA degradation.
messages: Cytoplasm
messages: DEAD-box RNA helicase involved in RNA degradation. Has RNA-dependent ATPase activity and unwinds double-stranded RNA.

216142:LT40 RS04900
gene id: 216142:LT40_RS04900
uniprot id: A0A089ZQ06
names: Similarity
messages: Belongs to the outer membrane porin (Opr) (TC 1.B.25) family.

216142:LT40 RS18460
gene id: 216142:LT40_RS18460
uniprot id: A0A089YUN3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

216142:LT40 RS09060
gene id: 216142:LT40_RS09060
uniprot id: A0A089YT54
names: Similarity
messages: Belongs to the mannose-6-phosphate isomerase type 2 family.

216142:LT40 RS05485
gene id: 216142:LT40_RS05485
uniprot id: A0A089YRB6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

216142:LT40 RS11450
gene id: 216142:LT40_RS11450
uniprot id: A0A089YQX7
names: Similarity
messages: Belongs to the RelB/DinJ antitoxin family.

216142:LT40 RS17860
gene id: 216142:LT40_RS17860
uniprot id: A0A089ZRE0
names: Function
names: Similarity
messages: Belongs to the peptidase M16 family.
messages: Required for coenzyme pyrroloquinoline quinone (PQQ) biosynthesis. It is thought that this protein is a protease that cleaves peptides bond in a small peptide (gene pqqA), providing the glutamate and tyrosine residues which are necessary for the synthesis of PQQ.

216142:LT40 RS04225
gene id: 216142:LT40_RS04225
uniprot id: A0A089ZPY0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

216142:LT40 RS16445
gene id: 216142:LT40_RS16445
uniprot id: A0A089ZR85
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

216142:LT40 RS03510
gene id: 216142:LT40_RS03510
uniprot id: A0A089YS56
names: Function
names: Similarity
messages: Belongs to the heat shock protein 70 family.
messages: Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB.

216142:LT40 RS14625
gene id: 216142:LT40_RS14625
uniprot id: A0A089YW13
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

216142:LT40 RS20160
gene id: 216142:LT40_RS20160
uniprot id: A0A089YVI0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

216142:LT40 RS13780
gene id: 216142:LT40_RS13780
uniprot id: A0A089YY84
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

216142:LT40 RS14945
gene id: 216142:LT40_RS14945
uniprot id: A0A089YQC1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane

216142:LT40 RS09070
gene id: 216142:LT40_RS09070
uniprot id: A0A089YPN9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell inner membrane
messages: Membrane

216142:LT40 RS07385
gene id: 216142:LT40_RS07385
uniprot id: A0A089YNT3
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

216142:LT40 RS18680
gene id: 216142:LT40_RS18680
uniprot id: A0A089YSF4
names: Similarity
messages: Belongs to the bleomycin resistance protein family.

216142:LT40 RS16305
gene id: 216142:LT40_RS16305
uniprot id: A0A089YR73
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell inner membrane
messages: Membrane

216142:LT40 RS18355
gene id: 216142:LT40_RS18355
uniprot id: A0A089YS81
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: Methylated by PrmB.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

216142:LT40 RS04675
gene id: 216142:LT40_RS04675
uniprot id: A0A089YMF0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.
messages: Homodimer.

216142:LT40 RS16890
gene id: 216142:LT40_RS16890
uniprot id: A0A089YTU4
names: Function
names: Similarity
messages: Belongs to the gamma-glutamylcyclotransferase family.
messages: Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides.

216142:LT40 RS01220
gene id: 216142:LT40_RS01220
uniprot id: A0A089YP19
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family. GlucD subfamily.

216142:LT40 RS12880
gene id: 216142:LT40_RS12880
uniprot id: A0A089YRL9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

216142:LT40 RS12830
gene id: 216142:LT40_RS12830
uniprot id: A0A089YRK8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

216142:LT40 RS00620
gene id: 216142:LT40_RS00620
uniprot id: A0A089YHY3
names: Similarity
messages: Belongs to the ferredoxin--NADP reductase type 1 family.

216142:LT40 RS00440
gene id: 216142:LT40_RS00440
uniprot id: A0A089YNQ2
names: Caution
names: Function
names: Similarity
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

216142:LT40 RS15905
gene id: 216142:LT40_RS15905
uniprot id: A0A089YT74
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

216142:LT40 RS03795
gene id: 216142:LT40_RS03795
uniprot id: A0A089YQB6
names: Function
names: Similarity
messages: Belongs to the ABC transporter superfamily. Outer membrane lipopolysaccharide export (TC 1.B.42) family.
messages: Part of the ABC transporter complex LptBFG involved in the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane. Probably responsible for energy coupling to the transport system.

216142:LT40 RS02850
gene id: 216142:LT40_RS02850
uniprot id: A0A089YPY1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit E family.
messages: Cell membrane
messages: Membrane

216142:LT40 RS00540
gene id: 216142:LT40_RS00540
uniprot id: A0A089YNR6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IspF family.
messages: Binds 1 divalent metal cation per subunit.
messages: Homotrimer.
messages: Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).

216142:LT40 RS13285
gene id: 216142:LT40_RS13285
uniprot id: A0A089YPI7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

216142:LT40 RS11210
gene id: 216142:LT40_RS11210
uniprot id: A0A089YNH3
names: Similarity
messages: Belongs to the PrpF family.

216142:LT40 RS18420
gene id: 216142:LT40_RS18420
uniprot id: A0A089ZRF9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

216142:LT40 RS00370
gene id: 216142:LT40_RS00370
uniprot id: A0A089YK55
names: Similarity
messages: Belongs to the ArsC family.

216142:LT40 RS04865
gene id: 216142:LT40_RS04865
uniprot id: A0A089YSW8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

216142:LT40 RS16660
gene id: 216142:LT40_RS16660
uniprot id: A0A089YTQ3
names: Similarity
names: Subunit
messages: Belongs to the aldehyde dehydrogenase family.
messages: Homotetramer.

216142:LT40 RS19665
gene id: 216142:LT40_RS19665
uniprot id: A0A089YVA4
names: Similarity
messages: Belongs to the HicA mRNA interferase family.

216142:LT40 RS18095
gene id: 216142:LT40_RS18095
uniprot id: A0A089YXT5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptD family.
messages: Cell outer membrane
messages: Component of the lipopolysaccharide transport and assembly complex. Interacts with LptE and LptA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane.

216142:LT40 RS03670
gene id: 216142:LT40_RS03670
uniprot id: A0A089YQ98
names: Subcellular Location Annotation
messages: Membrane

216142:LT40 RS18205
gene id: 216142:LT40_RS18205
uniprot id: A0A089YS55
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

216142:LT40 RS14610
gene id: 216142:LT40_RS14610
uniprot id: A0A089YSJ0
names: Similarity
messages: Belongs to the YggT family.

216142:LT40 RS18040
gene id: 216142:LT40_RS18040
uniprot id: A0A089ZRE6
names: Function
names: Similarity
messages: Belongs to the HPPK family.
messages: Catalyzes the transfer of pyrophosphate from adenosine triphosphate (ATP) to 6-hydroxymethyl-7,8-dihydropterin, an enzymatic step in folate biosynthesis pathway.

216142:LT40 RS12315
gene id: 216142:LT40_RS12315
uniprot id: A0A089YWN8
names: Similarity
messages: Belongs to the allantoicase family.

216142:LT40 RS15915
gene id: 216142:LT40_RS15915
uniprot id: A0A089ZR64
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

216142:LT40 RS06630
gene id: 216142:LT40_RS06630
uniprot id: A0A089ZQ69
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Cell membrane
messages: Membrane
messages: Responsible for the transport of dicarboxylates such as succinate, fumarate, and malate across the membrane.

216142:LT40 RS16440
gene id: 216142:LT40_RS16440
uniprot id: A0A089YZL4
names: Function
names: Similarity
messages: Belongs to the helicase family. RecG subfamily.
messages: Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA).

216142:LT40 RS06680
gene id: 216142:LT40_RS06680
uniprot id: A0A089ZQ71
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Cob(I)alamin adenosyltransferase family.
messages: Cytoplasm
messages: Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids.

216142:LT40 RS03505
gene id: 216142:LT40_RS03505
uniprot id: A0A089YLT6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HscB family.
messages: Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA.
messages: Interacts with HscA and stimulates its ATPase activity.

216142:LT40 RS17230
gene id: 216142:LT40_RS17230
uniprot id: A0A089Z012
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FdhD family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH.

216142:LT40 RS05850
gene id: 216142:LT40_RS05850
uniprot id: A0A089YKR8
names: PTM
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Hydantoinase/dihydropyrimidinase family.
messages: Carbamylation allows a single lysine to coordinate two divalent metal cations.

216142:LT40 RS02520
gene id: 216142:LT40_RS02520
uniprot id: A0A089YIZ2
names: Function
messages: Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors. CheA is autophosphorylated; it can transfer its phosphate group to either CheB or CheY.

216142:LT40 RS14505
gene id: 216142:LT40_RS14505
uniprot id: A0A089YYL4
names: Similarity
messages: Belongs to the peptidase S41A family.

216142:LT40 RS03630
gene id: 216142:LT40_RS03630
uniprot id: A0A089YLV7
names: Similarity
messages: Belongs to the bacterial solute-binding protein 5 family.

216142:LT40 RS09395
gene id: 216142:LT40_RS09395
uniprot id: A0A089YMI9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.
messages: Serves to protect the cell against DNA damage by alkyl hydroperoxides. It can use either NADH or NADPH as electron donor for direct reduction of redox dyes or of alkyl hydroperoxides when combined with the AhpC protein.

216142:LT40 RS07380
gene id: 216142:LT40_RS07380
uniprot id: A0A089YLH1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

216142:LT40 RS19300
gene id: 216142:LT40_RS19300
uniprot id: A0A089Z162
names: Similarity
messages: Belongs to the ferredoxin--NADP reductase type 1 family.

216142:LT40 RS13475
gene id: 216142:LT40_RS13475
uniprot id: A0A089ZQX3
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

216142:LT40 RS10255
gene id: 216142:LT40_RS10255
uniprot id: A0A089YMZ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. YhhS family.
messages: Cell inner membrane
messages: Membrane

216142:LT40 RS19185
gene id: 216142:LT40_RS19185
uniprot id: A0A089YSR0
names: Similarity
messages: Belongs to the intradiol ring-cleavage dioxygenase family.

216142:LT40 RS19330
gene id: 216142:LT40_RS19330
uniprot id: A0A089Z167
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptide transporter carbon starvation (CstA) (TC 2.A.114) family.
messages: Membrane

216142:LT40 RS15685
gene id: 216142:LT40_RS15685
uniprot id: A0A089ZR55
names: PTM
messages: Binds 2 heme c groups covalently per subunit.

216142:LT40 RS02580
gene id: 216142:LT40_RS02580
uniprot id: A0A089YRN3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmB/CycW/HelB family.
messages: Cell inner membrane
messages: Membrane
messages: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.

216142:LT40 RS11785
gene id: 216142:LT40_RS11785
uniprot id: A0A089YUJ2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.
messages: Catalyzes the conversion of L-lactate to pyruvate. Is coupled to the respiratory chain.
messages: Cell membrane
messages: Homotetramer.

216142:LT40 RS12870
gene id: 216142:LT40_RS12870
uniprot id: A0A089YV46
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

216142:LT40 RS16970
gene id: 216142:LT40_RS16970
uniprot id: A0A089YZW7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

216142:LT40 RS04610
gene id: 216142:LT40_RS04610
uniprot id: A0A089ZPZ5
names: Similarity
messages: Belongs to the RseA family.

216142:LT40 RS09870
gene id: 216142:LT40_RS09870
uniprot id: A0A089ZQJ0
names: Subcellular Location Annotation
messages: Membrane

216142:LT40 RS05085
gene id: 216142:LT40_RS05085
uniprot id: A0A089YR17
names: Similarity
messages: Belongs to the NtaA/SnaA/DszA monooxygenase family.

216142:LT40 RS06050
gene id: 216142:LT40_RS06050
uniprot id: A0A089YRK1
names: Subcellular Location Annotation
messages: Membrane

216142:LT40 RS04575
gene id: 216142:LT40_RS04575
uniprot id: A0A089YMC8
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

216142:LT40 RS13290
gene id: 216142:LT40_RS13290
uniprot id: A0A089YRT8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

216142:LT40 RS01025
gene id: 216142:LT40_RS01025
uniprot id: A0A089ZPK9
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

216142:LT40 RS03610
gene id: 216142:LT40_RS03610
uniprot id: A0A089YS75
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

216142:LT40 RS01075
gene id: 216142:LT40_RS01075
uniprot id: A0A089ZPL1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Membrane

216142:LT40 RS10620
gene id: 216142:LT40_RS10620
uniprot id: A0A089YVV7
names: Subcellular Location Annotation
messages: Membrane

216142:LT40 RS16355
gene id: 216142:LT40_RS16355
uniprot id: A0A089YR80
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PstS family.
messages: Involved in the system for phosphate transport across the cytoplasmic membrane.
messages: Periplasm
messages: Secreted

216142:LT40 RS15445
gene id: 216142:LT40_RS15445
uniprot id: A0A089YZ21
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anion channel-forming bestrophin (TC 1.A.46) family.
messages: Membrane

216142:LT40 RS11985
gene id: 216142:LT40_RS11985
uniprot id: A0A089YNT6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

216142:LT40 RS14560
gene id: 216142:LT40_RS14560
uniprot id: A0A089YYM3
names: Similarity
messages: Belongs to the UPF0301 (AlgH) family.

216142:LT40 RS15460
gene id: 216142:LT40_RS15460
uniprot id: A0A089YQK2
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

216142:LT40 RS14285
gene id: 216142:LT40_RS14285
uniprot id: A0A089YVW2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
messages: Belongs to the ClpX chaperone family. HslU subfamily.
messages: Cytoplasm

216142:LT40 RS18300
gene id: 216142:LT40_RS18300
uniprot id: A0A089YXW5
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

216142:LT40 RS18855
gene id: 216142:LT40_RS18855
uniprot id: A0A089YSL0
names: Similarity
messages: Belongs to the DNA polymerase HolA subunit family.

216142:LT40 RS02630
gene id: 216142:LT40_RS02630
uniprot id: A0A089YRP4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic sulfate-binding protein family.
messages: Periplasm

216142:LT40 RS05745
gene id: 216142:LT40_RS05745
uniprot id: A0A089YRF4
names: Similarity
messages: Belongs to the helicase family. RecQ subfamily.

216142:LT40 RS12585
gene id: 216142:LT40_RS12585
uniprot id: A0A089YWT6
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.

216142:LT40 RS16535
gene id: 216142:LT40_RS16535
uniprot id: A0A089YTN0
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

216142:LT40 RS09690
gene id: 216142:LT40_RS09690
uniprot id: A0A089YVB5
names: Similarity
messages: Belongs to the SCO1/2 family.

216142:LT40 RS19290
gene id: 216142:LT40_RS19290
uniprot id: A0A089YST0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

216142:LT40 RS06240
gene id: 216142:LT40_RS06240
uniprot id: A0A089YKY1
names: Subcellular Location Annotation
messages: Membrane

216142:LT40 RS06715
gene id: 216142:LT40_RS06715
uniprot id: A0A089YL53
names: Function
names: Similarity
messages: Belongs to the CobT family.
messages: Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB).

216142:LT40 RS08135
gene id: 216142:LT40_RS08135
uniprot id: A0A089ZQC5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TspO/BZRP family.
messages: Membrane

216142:LT40 RS04030
gene id: 216142:LT40_RS04030
uniprot id: A0A089YQE7
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

216142:LT40 RS08020
gene id: 216142:LT40_RS08020
uniprot id: A0A089YSP0
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

216142:LT40 RS16905
gene id: 216142:LT40_RS16905
uniprot id: A0A089YXB4
names: Subcellular Location Annotation
messages: Nucleus

216142:LT40 RS18720
gene id: 216142:LT40_RS18720
uniprot id: A0A089ZRH0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PPase family.
messages: Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
messages: Cytoplasm
messages: Homohexamer.

216142:LT40 RS02140
gene id: 216142:LT40_RS02140
uniprot id: A0A089ZPQ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

216142:LT40 RS00900
gene id: 216142:LT40_RS00900
uniprot id: A0A089ZPK5
names: Subcellular Location Annotation
messages: Cytoplasm

216142:LT40 RS16680
gene id: 216142:LT40_RS16680
uniprot id: A0A089YRD4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

216142:LT40 RS04800
gene id: 216142:LT40_RS04800
uniprot id: A0A089YQW3
names: Function
names: Similarity
messages: Belongs to the MinE family.
messages: Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.

216142:LT40 RS17795
gene id: 216142:LT40_RS17795
uniprot id: A0A089YRW7
names: Subcellular Location Annotation
messages: Membrane

216142:LT40 RS08245
gene id: 216142:LT40_RS08245
uniprot id: A0A089YSS1
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

216142:LT40 RS18570
gene id: 216142:LT40_RS18570
uniprot id: A0A089ZRG5
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion.
messages: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.
messages: In the C-terminal section; belongs to the HTP reductase family.
messages: In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family.

216142:LT40 RS07465
gene id: 216142:LT40_RS07465
uniprot id: A0A089YU73
names: Activity Regulation
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.
messages: Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.
messages: Belongs to the carbohydrate kinase pfkB family.
messages: Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate.

216142:LT40 RS13645
gene id: 216142:LT40_RS13645
uniprot id: A0A089YY63
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SIMIBI class G3E GTPase family. UreG subfamily.
messages: Cytoplasm
messages: Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG.
messages: Homodimer. UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

216142:LT40 RS10665
gene id: 216142:LT40_RS10665
uniprot id: A0A089YQH8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PstS family.
messages: Part of the ABC transporter complex PstSACB involved in phosphate import.
messages: The complex is composed of two ATP-binding proteins (PstB), two transmembrane proteins (PstC and PstA) and a solute-binding protein (PstS).

216142:LT40 RS04690
gene id: 216142:LT40_RS04690
uniprot id: A0A089YQU2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ArsB family.
messages: Cell membrane
messages: Involved in arsenical resistance. Thought to form the channel of an arsenite pump.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

216142:LT40 RS00870
gene id: 216142:LT40_RS00870
uniprot id: A0A089YQR5
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

216142:LT40 RS00685
gene id: 216142:LT40_RS00685
uniprot id: A0A089YKA0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YceF subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes 7-methyl-GTP (m(7)GTP). May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

216142:LT40 RS11990
gene id: 216142:LT40_RS11990
uniprot id: A0A089YR52
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

216142:LT40 RS07745
gene id: 216142:LT40_RS07745
uniprot id: A0A089YLQ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliR/MopE/SpaR family.
messages: Cell membrane
messages: Membrane

216142:LT40 RS16625
gene id: 216142:LT40_RS16625
uniprot id: A0A089YX72
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. Xpt subfamily.
messages: Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis.
messages: Cytoplasm
messages: Homodimer.

216142:LT40 RS02980
gene id: 216142:LT40_RS02980
uniprot id: A0A089YPZ5
names: Similarity
messages: Belongs to the ABC transporter superfamily.

216142:LT40 RS04600
gene id: 216142:LT40_RS04600
uniprot id: A0A089YMD3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily.
messages: Catalyzes the oxidation of L-aspartate to iminoaspartate.
messages: Cytoplasm

216142:LT40 RS14030
gene id: 216142:LT40_RS14030
uniprot id: A0A089YPX9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. Biotin synthase family.
messages: Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
messages: Homodimer.

216142:LT40 RS06735
gene id: 216142:LT40_RS06735
uniprot id: A0A089YRU6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OmpP1/FadL family.
messages: Cell outer membrane
messages: Membrane

216142:LT40 RS12915
gene id: 216142:LT40_RS12915
uniprot id: A0A089YRM4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

216142:LT40 RS01210
gene id: 216142:LT40_RS01210
uniprot id: A0A089YQX5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

216142:LT40 RS05545
gene id: 216142:LT40_RS05545
uniprot id: A0A089YN00
names: Activity Regulation
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Inhibited by fructose 1,6-bisphosphate (FBP).
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.

216142:LT40 RS00585
gene id: 216142:LT40_RS00585
uniprot id: A0A089ZPJ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

216142:LT40 RS12110
gene id: 216142:LT40_RS12110
uniprot id: A0A089YUP2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Conversion of NADPH, generated by peripheral catabolic pathways, to NADH, which can enter the respiratory chain for energy generation.
messages: Cytoplasm

216142:LT40 RS17045
gene id: 216142:LT40_RS17045
uniprot id: A0A089YTW7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family.
messages: Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system.
messages: The complex is composed of two ATP-binding proteins (PotA), two transmembrane proteins (PotB and PotC) and a solute-binding protein (PotD).

216142:LT40 RS14690
gene id: 216142:LT40_RS14690
uniprot id: A0A089YYP6
names: Similarity
messages: Belongs to the peptidase M16 family.

216142:LT40 RS14685
gene id: 216142:LT40_RS14685
uniprot id: A0A089YSK3
names: Similarity
messages: Belongs to the peptidase M16 family.

216142:LT40 RS15725
gene id: 216142:LT40_RS15725
uniprot id: A0A089YT39
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

216142:LT40 RS03665
gene id: 216142:LT40_RS03665
uniprot id: A0A089ZPV8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

216142:LT40 RS16955
gene id: 216142:LT40_RS16955
uniprot id: A0A089YXC3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvT family.
messages: The glycine cleavage system catalyzes the degradation of glycine.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

216142:LT40 RS01035
gene id: 216142:LT40_RS01035
uniprot id: A0A089YI51
names: Similarity
messages: Belongs to the prokaryotic/mitochondrial release factor family.

216142:LT40 RS15170
gene id: 216142:LT40_RS15170
uniprot id: A0A089YYX7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

216142:LT40 RS02295
gene id: 216142:LT40_RS02295
uniprot id: A0A089YL35
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of a number of rings mounted on a central rod.

216142:LT40 RS03690
gene id: 216142:LT40_RS03690
uniprot id: A0A089ZPV9
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

216142:LT40 RS17645
gene id: 216142:LT40_RS17645
uniprot id: A0A089ZRD2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RlmJ family.
messages: Monomer.
messages: Specifically methylates the adenine in position 2030 of 23S rRNA.

216142:LT40 RS10560
gene id: 216142:LT40_RS10560
uniprot id: A0A089YQF2
names: Subcellular Location Annotation
messages: Membrane

216142:LT40 RS02070
gene id: 216142:LT40_RS02070
uniprot id: A0A089YRB8
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

216142:LT40 RS08985
gene id: 216142:LT40_RS08985
uniprot id: A0A089YMC1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.

216142:LT40 RS15635
gene id: 216142:LT40_RS15635
uniprot id: A0A089ZR53
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ivy family.
messages: Periplasm

216142:LT40 RS08430
gene id: 216142:LT40_RS08430
uniprot id: A0A089YPF8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial sugar transferase family.
messages: Membrane

216142:LT40 RS01105
gene id: 216142:LT40_RS01105
uniprot id: A0A089YNZ7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinylarginine dihydrolase family.
messages: Catalyzes the hydrolysis of N(2)-succinylarginine into N(2)-succinylornithine, ammonia and CO(2).
messages: Homodimer.

216142:LT40 RS14035
gene id: 216142:LT40_RS14035
uniprot id: A0A089YSA2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily.
messages: Catalyzes the decarboxylative condensation of pimeloyl-[acyl-carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide.
messages: Homodimer.

216142:LT40 RS15355
gene id: 216142:LT40_RS15355
uniprot id: A0A089ZR44
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the ABC transporter complex (TC 3.A.1.6.1) involved in sulfate/thiosulfate import.
messages: Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (CysA), two transmembrane proteins (CysT and CysW) and a solute-binding protein (CysP).

216142:LT40 RS20665
gene id: 216142:LT40_RS20665
uniprot id: A0A089YZ17
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

216142:LT40 RS07030
gene id: 216142:LT40_RS07030
uniprot id: A0A089YNM1
names: Similarity
messages: Belongs to the FAD-dependent oxidoreductase family.

216142:LT40 RS16790
gene id: 216142:LT40_RS16790
uniprot id: A0A089YZT2
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Involved in a late step of protoheme IX synthesis.
messages: Membrane

216142:LT40 RS10670
gene id: 216142:LT40_RS10670
uniprot id: A0A089YVW9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

216142:LT40 RS02665
gene id: 216142:LT40_RS02665
uniprot id: A0A089ZPS0
names: Similarity
messages: Belongs to the manganese catalase family.

216142:LT40 RS13840
gene id: 216142:LT40_RS13840
uniprot id: A0A089YVP7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueG family.
messages: Binds 2 [4Fe-4S] clusters per monomer.
messages: Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

216142:LT40 RS05975
gene id: 216142:LT40_RS05975
uniprot id: A0A089YRJ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

216142:LT40 RS19745
gene id: 216142:LT40_RS19745
uniprot id: A0A089YVB6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

216142:LT40 RS04120
gene id: 216142:LT40_RS04120
uniprot id: A0A089YSH0
names: Function
names: Similarity
messages: Belongs to the ketopantoate reductase family.
messages: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.

216142:LT40 RS17635
gene id: 216142:LT40_RS17635
uniprot id: A0A089YU69
names: Function
names: Similarity
messages: In the C-terminal section; belongs to the aldehyde dehydrogenase family.
messages: In the N-terminal section; belongs to the proline dehydrogenase family.
messages: Oxidizes proline to glutamate for use as a carbon and nitrogen source.

216142:LT40 RS11315
gene id: 216142:LT40_RS11315
uniprot id: A0A089YNI5
names: Similarity
names: Subunit
messages: Belongs to the Nudix hydrolase family. NudJ subfamily.
messages: Monomer.

216142:LT40 RS16775
gene id: 216142:LT40_RS16775
uniprot id: A0A089YX97
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HMBS family.
messages: Binds 1 dipyrromethane group covalently.
messages: Monomer.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
messages: The porphobilinogen subunits are added to the dipyrromethane group.

216142:LT40 RS12885
gene id: 216142:LT40_RS12885
uniprot id: A0A089YWZ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

216142:LT40 RS09815
gene id: 216142:LT40_RS09815
uniprot id: A0A089ZQI8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 2 family.
messages: Periplasm

216142:LT40 RS03740
gene id: 216142:LT40_RS03740
uniprot id: A0A089ZPW1
names: Similarity
messages: Belongs to the peptidase U62 family.

216142:LT40 RS16315
gene id: 216142:LT40_RS16315
uniprot id: A0A089YZJ3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

216142:LT40 RS16350
gene id: 216142:LT40_RS16350
uniprot id: A0A089YX29
names: Subcellular Location Annotation
messages: Membrane

216142:LT40 RS10880
gene id: 216142:LT40_RS10880
uniprot id: A0A089YW18
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Mediates global changes in gene expression, shifting from rapid growth to stress survival by linking envelope stress, the stringent response and the catabolite repression systems. Usually binds in the 5'-UTR; binding at or near the Shine-Dalgarno sequence prevents ribosome-binding, repressing translation, binding elsewhere in the 5'-UTR can activate translation and/or stabilize the mRNA. Its function is antagonized by small RNA(s).
messages: Belongs to the CsrA/RsmA family.
messages: Cytoplasm
messages: Homodimer; the beta-strands of each monomer intercalate to form a hydrophobic core, while the alpha-helices form wings that extend away from the core.

216142:LT40 RS00165
gene id: 216142:LT40_RS00165
uniprot id: A0A089YHS6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homodimer.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

216142:LT40 RS09305
gene id: 216142:LT40_RS09305
uniprot id: A0A089YV40
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DyP-type peroxidase family. EfeB subfamily.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group non-covalently per subunit.
messages: Homodimer. Part of a ferrous iron transporter composed of EfeU, EfeO and EfeB.
messages: Involved in the recovery of exogenous heme iron. Extracts iron from heme while preserving the protoporphyrin ring intact.
messages: Periplasm

216142:LT40 RS13150
gene id: 216142:LT40_RS13150
uniprot id: A0A089ZQW1
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

216142:LT40 RS03700
gene id: 216142:LT40_RS03700
uniprot id: A0A089YJK5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

216142:LT40 RS00240
gene id: 216142:LT40_RS00240
uniprot id: A0A089YK35
names: Similarity
messages: In the C-terminal section; belongs to the anthranilate synthase component I family.

216142:LT40 RS05360
gene id: 216142:LT40_RS05360
uniprot id: A0A089ZQ22
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.

216142:LT40 RS02745
gene id: 216142:LT40_RS02745
uniprot id: A0A089ZPS3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

216142:LT40 RS00975
gene id: 216142:LT40_RS00975
uniprot id: A0A089YQT4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccD/PCCB family.
messages: Binds 1 zinc ion per subunit.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

216142:LT40 RS16475
gene id: 216142:LT40_RS16475
uniprot id: A0A089YX49
names: Similarity
messages: Belongs to the RutC family.

216142:LT40 RS11980
gene id: 216142:LT40_RS11980
uniprot id: A0A089YUL8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

216142:LT40 RS08515
gene id: 216142:LT40_RS08515
uniprot id: A0A089YUS3
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

216142:LT40 RS13965
gene id: 216142:LT40_RS13965
uniprot id: A0A089YYB3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family. ParE type 1 subfamily.
messages: Heterotetramer composed of ParC and ParE.
messages: Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.

216142:LT40 RS00625
gene id: 216142:LT40_RS00625
uniprot id: A0A089YK92
names: Similarity
messages: Belongs to the tRNA methyltransferase O family.

216142:LT40 RS16040
gene id: 216142:LT40_RS16040
uniprot id: A0A089ZR69
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

216142:LT40 RS07140
gene id: 216142:LT40_RS07140
uniprot id: A0A089YLC5
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

216142:LT40 RS04935
gene id: 216142:LT40_RS04935
uniprot id: A0A089YKA3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homodimer.

216142:LT40 RS16730
gene id: 216142:LT40_RS16730
uniprot id: A0A089YRE1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

216142:LT40 RS15450
gene id: 216142:LT40_RS15450
uniprot id: A0A089ZR47
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily.

216142:LT40 RS03335
gene id: 216142:LT40_RS03335
uniprot id: A0A089YQ50
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
messages: Carbon 2 of the heme B porphyrin ring is defined according to the Fischer nomenclature.
messages: Cell membrane
messages: Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
messages: Membrane

216142:LT40 RS17405
gene id: 216142:LT40_RS17405
uniprot id: A0A089Z048
names: Similarity
messages: Belongs to the peptidase U62 family.

216142:LT40 RS13880
gene id: 216142:LT40_RS13880
uniprot id: A0A089YS78
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-to-5' exoribonuclease specific for small oligoribonucleotides.
messages: Belongs to the oligoribonuclease family.
messages: Cytoplasm

216142:LT40 RS13465
gene id: 216142:LT40_RS13465
uniprot id: A0A089YS17
names: Function
names: Similarity
messages: Belongs to the Dus family. DusB subfamily.
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

216142:LT40 RS14675
gene id: 216142:LT40_RS14675
uniprot id: A0A089YW24
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Homodimer. Forms a membrane-associated complex with FtsX.
messages: Part of the ABC transporter FtsEX involved in cellular division. Important for assembly or stability of the septal ring.

216142:LT40 RS15300
gene id: 216142:LT40_RS15300
uniprot id: A0A089ZR42
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NlpA lipoprotein family.
messages: Membrane

216142:LT40 RS12405
gene id: 216142:LT40_RS12405
uniprot id: A0A089YP11
names: Similarity
messages: Belongs to the lycopene cyclase family.

216142:LT40 RS10550
gene id: 216142:LT40_RS10550
uniprot id: A0A089YTW9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

216142:LT40 RS18455
gene id: 216142:LT40_RS18455
uniprot id: A0A089YSA6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

216142:LT40 RS11195
gene id: 216142:LT40_RS11195
uniprot id: A0A089YW58
names: Function
names: Similarity
names: Subunit
messages: Belongs to the isocitrate lyase/PEP mutase superfamily. Methylisocitrate lyase family.
messages: Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate.
messages: Homotetramer; dimer of dimers.
messages: Involved in the catabolism of short chain fatty acids (SCFA) via the 2-methylcitrate cycle (propionate degradation route). Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate via an alpha-carboxy-carbanion intermediate.

216142:LT40 RS02525
gene id: 216142:LT40_RS02525
uniprot id: A0A089YL84
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CheB family.
messages: Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.
messages: Cytoplasm
messages: Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
messages: Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity.

216142:LT40 RS15960
gene id: 216142:LT40_RS15960
uniprot id: A0A089YZD0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

216142:LT40 RS03950
gene id: 216142:LT40_RS03950
uniprot id: A0A089YJQ1
names: Cofactor
messages: Binds 1 heme c group covalently per subunit.

216142:LT40 RS18880
gene id: 216142:LT40_RS18880
uniprot id: A0A089YY80
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CN hydrolase family. Apolipoprotein N-acyltransferase subfamily.
messages: Catalyzes the phospholipid dependent N-acylation of the N-terminal cysteine of apolipoprotein, the last step in lipoprotein maturation.
messages: Cell membrane
messages: Membrane

216142:LT40 RS18615
gene id: 216142:LT40_RS18615
uniprot id: A0A089YUS0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

216142:LT40 RS03765
gene id: 216142:LT40_RS03765
uniprot id: A0A089ZPW2
names: Subcellular Location Annotation
messages: Membrane

216142:LT40 RS08255
gene id: 216142:LT40_RS08255
uniprot id: A0A089YPD5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
messages: Cell inner membrane
messages: Membrane

216142:LT40 RS04840
gene id: 216142:LT40_RS04840
uniprot id: A0A089YSW3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

216142:LT40 RS02020
gene id: 216142:LT40_RS02020
uniprot id: A0A089YRA6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

216142:LT40 RS16030
gene id: 216142:LT40_RS16030
uniprot id: A0A089YT98
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Binds two Mg(2+) per subunit. The magnesium ions form salt bridges with both the protein and the DNA. Can also accept other divalent metal cations, such as Mn(2+) or Ca(2+).
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

216142:LT40 RS04820
gene id: 216142:LT40_RS04820
uniprot id: A0A089ZQ03
names: Similarity
messages: Belongs to the MlaA family.

216142:LT40 RS02975
gene id: 216142:LT40_RS02975
uniprot id: A0A089ZPT1
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

216142:LT40 RS20765
gene id: 216142:LT40_RS20765
uniprot id: A0A089ZRP7
names: Subcellular Location Annotation
messages: Membrane

216142:LT40 RS02535
gene id: 216142:LT40_RS02535
uniprot id: A0A089ZPR5
names: Similarity
messages: Belongs to the MotB family.

216142:LT40 RS17845
gene id: 216142:LT40_RS17845
uniprot id: A0A089YRX8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PqqD family.
messages: Functions as a PqqA binding protein and presents PqqA to PqqE, in the pyrroloquinoline quinone (PQQ) biosynthetic pathway.
messages: Monomer. Interacts with PqqE.

216142:LT40 RS15715
gene id: 216142:LT40_RS15715
uniprot id: A0A089YWN0
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Fur family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.

216142:LT40 RS14935
gene id: 216142:LT40_RS14935
uniprot id: A0A089ZR29
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Membrane

216142:LT40 RS14575
gene id: 216142:LT40_RS14575
uniprot id: A0A089YQ65
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

216142:LT40 RS16795
gene id: 216142:LT40_RS16795
uniprot id: A0A089ZR99
names: Similarity
messages: Belongs to the Rsd/AlgQ family.

216142:LT40 RS01235
gene id: 216142:LT40_RS01235
uniprot id: A0A089YQX9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the OMP decarboxylase family. Type 1 subfamily.
messages: Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
messages: Homodimer.

216142:LT40 RS05335
gene id: 216142:LT40_RS05335
uniprot id: A0A089ZQ21
names: Function
names: Similarity
messages: Belongs to the bacterioferritin family.
messages: Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex.

216142:LT40 RS14725
gene id: 216142:LT40_RS14725
uniprot id: A0A089ZR21
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FPG family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
messages: Monomer.

216142:LT40 RS12160
gene id: 216142:LT40_RS12160
uniprot id: A0A089YUQ3
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

216142:LT40 RS03790
gene id: 216142:LT40_RS03790
uniprot id: A0A089ZPW3
names: Function
names: Similarity
messages: Belongs to the sigma-54 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

216142:LT40 RS12875
gene id: 216142:LT40_RS12875
uniprot id: A0A089YP93
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

216142:LT40 RS10765
gene id: 216142:LT40_RS10765
uniprot id: A0A089ZQM3
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

216142:LT40 RS18220
gene id: 216142:LT40_RS18220
uniprot id: A0A089ZRF3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HesB/IscA family.
messages: Binds 1 iron-sulfur cluster per subunit.
messages: Homodimer.
messages: Required for insertion of 4Fe-4S clusters for at least IspG.

216142:LT40 RS00425
gene id: 216142:LT40_RS00425
uniprot id: A0A089YK62
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

216142:LT40 RS11310
gene id: 216142:LT40_RS11310
uniprot id: A0A089YUC3
names: Cofactor
names: Similarity
messages: Belongs to the monomeric-type IDH family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

216142:LT40 RS03115
gene id: 216142:LT40_RS03115
uniprot id: A0A089YLM7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. METTL16/RlmF family.
messages: Cytoplasm
messages: Specifically methylates the adenine in position 1618 of 23S rRNA.

216142:LT40 RS01965
gene id: 216142:LT40_RS01965
uniprot id: A0A089YR94
names: Subcellular Location Annotation
messages: Membrane

216142:LT40 RS14485
gene id: 216142:LT40_RS14485
uniprot id: A0A089ZR12
names: Function
names: Similarity
messages: Belongs to the glutaredoxin family.
messages: Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins.

216142:LT40 RS05010
gene id: 216142:LT40_RS05010
uniprot id: A0A089YR07
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the quinolinate synthase family. Type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
messages: Cytoplasm

216142:LT40 RS16050
gene id: 216142:LT40_RS16050
uniprot id: A0A089YQZ1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

216142:LT40 RS15455
gene id: 216142:LT40_RS15455
uniprot id: A0A089YWH2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell outer membrane

216142:LT40 RS09765
gene id: 216142:LT40_RS09765
uniprot id: A0A089YMP5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

216142:LT40 RS17585
gene id: 216142:LT40_RS17585
uniprot id: A0A089YU53
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the uroporphyrinogen decarboxylase family.
messages: Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

216142:LT40 RS14320
gene id: 216142:LT40_RS14320
uniprot id: A0A089YSE9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRA-PH family.
messages: Cytoplasm

216142:LT40 RS18765
gene id: 216142:LT40_RS18765
uniprot id: A0A089Z0X2
names: Subcellular Location Annotation
messages: Membrane

216142:LT40 RS20355
gene id: 216142:LT40_RS20355
uniprot id: A0A089YVM0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

216142:LT40 RS01865
gene id: 216142:LT40_RS01865
uniprot id: A0A089YR76
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

216142:LT40 RS04425
gene id: 216142:LT40_RS04425
uniprot id: A0A089YSM2
names: Subcellular Location Annotation
messages: Membrane

216142:LT40 RS08870
gene id: 216142:LT40_RS08870
uniprot id: A0A089ZQF3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Basic amino acid/polyamine antiporter (APA) (TC 2.A.3.2) family.
messages: Catalyzes both the uptake and excretion of putrescine. The uptake of putrescine is dependent on the membrane potential and the excretion involves putrescine-ornithine antiporter activity.
messages: Cell inner membrane
messages: Membrane

216142:LT40 RS00500
gene id: 216142:LT40_RS00500
uniprot id: A0A089YK74
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

216142:LT40 RS02485
gene id: 216142:LT40_RS02485
uniprot id: A0A089ZPR3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type III secretion exporter family.
messages: Cell membrane
messages: Membrane
messages: Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

216142:LT40 RS15280
gene id: 216142:LT40_RS15280
uniprot id: A0A089YWD2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ribose 5-phosphate isomerase family.
messages: Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
messages: Homodimer.

216142:LT40 RS02740
gene id: 216142:LT40_RS02740
uniprot id: A0A089YRV0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Cell inner membrane
messages: Membrane

216142:LT40 RS14305
gene id: 216142:LT40_RS14305
uniprot id: A0A089ZR05
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiJ family.
messages: Cytoplasm
messages: Required for ubiquinone (coenzyme Q) biosynthesis. Binds hydrophobic ubiquinone biosynthetic intermediates via its SCP2 domain and is essential for the stability of the Ubi complex. May constitute a docking platform where Ubi enzymes assemble and access their SCP2-bound polyprenyl substrates.

216142:LT40 RS15075
gene id: 216142:LT40_RS15075
uniprot id: A0A089YW95
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

216142:LT40 RS13070
gene id: 216142:LT40_RS13070
uniprot id: A0A089YPE0
names: Caution
names: Similarity
messages: Belongs to the globin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

216142:LT40 RS10265
gene id: 216142:LT40_RS10265
uniprot id: A0A089YVM4
names: Domain
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 dependent methionine synthase family.
messages: Catalyzes the transfer of a methyl group from methyl-cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
messages: Modular enzyme with four functionally distinct domains. The isolated Hcy-binding domain catalyzes methyl transfer from free methylcobalamin to homocysteine. The Hcy-binding domain in association with the pterin-binding domain catalyzes the methylation of cob(I)alamin by methyltetrahydrofolate and the methylation of homocysteine. The B12-binding domain binds the cofactor. The AdoMet activation domain binds S-adenosyl-L-methionine. Under aerobic conditions cob(I)alamin can be converted to inactive cob(II)alamin. Reductive methylation by S-adenosyl-L-methionine and flavodoxin regenerates methylcobalamin.

216142:LT40 RS02310
gene id: 216142:LT40_RS02310
uniprot id: A0A089YPK6
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.

216142:LT40 RS04160
gene id: 216142:LT40_RS04160
uniprot id: A0A089YJT7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

216142:LT40 RS03605
gene id: 216142:LT40_RS03605
uniprot id: A0A089YLV3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

216142:LT40 RS16855
gene id: 216142:LT40_RS16855
uniprot id: A0A089YXA8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

216142:LT40 RS01705
gene id: 216142:LT40_RS01705
uniprot id: A0A089YKQ4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

216142:LT40 RS16685
gene id: 216142:LT40_RS16685
uniprot id: A0A089YTQ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiK family.
messages: Cytoplasm
messages: Required for efficient ubiquinone (coenzyme Q) biosynthesis. UbiK is probably an accessory factor of Ubi enzymes and facilitates ubiquinone biosynthesis by acting as an assembly factor, a targeting factor, or both.

216142:LT40 RS18025
gene id: 216142:LT40_RS18025
uniprot id: A0A089YS09
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

216142:LT40 RS04780
gene id: 216142:LT40_RS04780
uniprot id: A0A089YK66
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TtcA family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is chelated by three Cys residues, the fourth Fe has a free coordination site that may bind a sulfur atom transferred from the persulfide of IscS.
messages: Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system.
messages: Cytoplasm
messages: Homodimer.
messages: The thiolation reaction likely consists of two steps: a first activation step by ATP to form an adenylated intermediate of the target base of tRNA, and a second nucleophilic substitution step of the sulfur (S) atom supplied by the hydrosulfide attached to the Fe-S cluster.

216142:LT40 RS01625
gene id: 216142:LT40_RS01625
uniprot id: A0A089YR34
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

216142:LT40 RS07750
gene id: 216142:LT40_RS07750
uniprot id: A0A089YP12
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliQ/MopD/SpaQ family.
messages: Cell membrane
messages: Membrane

216142:LT40 RS07755
gene id: 216142:LT40_RS07755
uniprot id: A0A089YUD5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliP/MopC/SpaP family.
messages: Cell membrane
messages: Membrane

216142:LT40 RS07115
gene id: 216142:LT40_RS07115
uniprot id: A0A089YNN4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

216142:LT40 RS00420
gene id: 216142:LT40_RS00420
uniprot id: A0A089YHV6
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Inhibited by UTP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

216142:LT40 RS07525
gene id: 216142:LT40_RS07525
uniprot id: A0A089YSB0
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

216142:LT40 RS10130
gene id: 216142:LT40_RS10130
uniprot id: A0A089YVJ1
names: Subcellular Location Annotation
messages: Membrane

216142:LT40 RS20415
gene id: 216142:LT40_RS20415
uniprot id: A0A089YVN3
names: Similarity
messages: Belongs to the RecJ family.

216142:LT40 RS19535
gene id: 216142:LT40_RS19535
uniprot id: A0A089Z1A3
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

216142:LT40 RS02325
gene id: 216142:LT40_RS02325
uniprot id: A0A089YL40
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

216142:LT40 RS03465
gene id: 216142:LT40_RS03465
uniprot id: A0A089ZPV0
names: Similarity
messages: Belongs to the peptidase M20A family. ArgE subfamily.

216142:LT40 RS01450
gene id: 216142:LT40_RS01450
uniprot id: A0A089YIC1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

216142:LT40 RS18955
gene id: 216142:LT40_RS18955
uniprot id: A0A089YY93
names: Subcellular Location Annotation
messages: Membrane

216142:LT40 RS17275
gene id: 216142:LT40_RS17275
uniprot id: A0A089YU00
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

216142:LT40 RS04375
gene id: 216142:LT40_RS04375
uniprot id: A0A089YSL3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell outer membrane

216142:LT40 RS16825
gene id: 216142:LT40_RS16825
uniprot id: A0A089ZRA0
names: Function
names: Similarity
messages: Belongs to the peptidase C56 family.
messages: Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate.

216142:LT40 RS17195
gene id: 216142:LT40_RS17195
uniprot id: A0A089YRM0
names: Similarity
messages: Belongs to the HSP15 family.

216142:LT40 RS05305
gene id: 216142:LT40_RS05305
uniprot id: A0A089YT51
names: Caution
names: Function
names: Similarity
messages: Belongs to the Dus family. DusC subfamily.
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U16 in tRNAs.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

216142:LT40 RS13680
gene id: 216142:LT40_RS13680
uniprot id: A0A089YVM5
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

216142:LT40 RS18045
gene id: 216142:LT40_RS18045
uniprot id: A0A089YXS4
names: Cofactor
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: A single active site specifically recognizes both ATP and CTP and is responsible for their addition.
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. Bacterial CCA-adding enzyme type 1 subfamily.
messages: Catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. tRNA 3'-terminal CCA addition is required both for tRNA processing and repair. Also involved in tRNA surveillance by mediating tandem CCA addition to generate a CCACCA at the 3' terminus of unstable tRNAs. While stable tRNAs receive only 3'-terminal CCA, unstable tRNAs are marked with CCACCA and rapidly degraded.
messages: Comprises two domains: an N-terminal domain containing the nucleotidyltransferase activity and a C-terminal HD domain associated with both phosphodiesterase and phosphatase activities.
messages: Magnesium is required for nucleotidyltransferase activity.
messages: Monomer. Can also form homodimers and oligomers.
messages: Nickel for phosphatase activity.

216142:LT40 RS13885
gene id: 216142:LT40_RS13885
uniprot id: A0A089YYA1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

216142:LT40 RS04960
gene id: 216142:LT40_RS04960
uniprot id: A0A089YKB0
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

216142:LT40 RS20610
gene id: 216142:LT40_RS20610
uniprot id: A0A089YZ06
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fimbrial export usher family.
messages: Cell outer membrane

216142:LT40 RS20205
gene id: 216142:LT40_RS20205
uniprot id: A0A089YT80
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

216142:LT40 RS04845
gene id: 216142:LT40_RS04845
uniprot id: A0A089ZQ04
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

216142:LT40 RS11480
gene id: 216142:LT40_RS11480
uniprot id: A0A089YW96
names: Subcellular Location Annotation
messages: Membrane

216142:LT40 RS16555
gene id: 216142:LT40_RS16555
uniprot id: A0A089YRB3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

216142:LT40 RS15185
gene id: 216142:LT40_RS15185
uniprot id: A0A089YQF0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family.
messages: Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system.
messages: The complex is composed of two ATP-binding proteins (PotA), two transmembrane proteins (PotB and PotC) and a solute-binding protein (PotD).

216142:LT40 RS13890
gene id: 216142:LT40_RS13890
uniprot id: A0A089ZQY9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

216142:LT40 RS15555
gene id: 216142:LT40_RS15555
uniprot id: A0A089YZ35
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

216142:LT40 RS16630
gene id: 216142:LT40_RS16630
uniprot id: A0A089YRC6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. UvrD subfamily.
messages: Homodimer.
messages: Rep helicase is a single-stranded DNA-dependent ATPase involved in DNA replication; it can initiate unwinding at a nick in the DNA. It binds to the single-stranded DNA and acts in a progressive fashion along the DNA in the 3' to 5' direction.

216142:LT40 RS12125
gene id: 216142:LT40_RS12125
uniprot id: A0A089YWK2
names: Similarity
messages: Belongs to the pirin family.

216142:LT40 RS11180
gene id: 216142:LT40_RS11180
uniprot id: A0A089YUA4
names: Similarity
messages: Belongs to the peptidase C56 family.

216142:LT40 RS19285
gene id: 216142:LT40_RS19285
uniprot id: A0A089YYF4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Cell inner membrane
messages: Membrane

216142:LT40 RS18430
gene id: 216142:LT40_RS18430
uniprot id: A0A089YSA0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

216142:LT40 RS14240
gene id: 216142:LT40_RS14240
uniprot id: A0A089YQ11
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits).
messages: In the C-terminal section; belongs to the transpeptidase family.
messages: In the N-terminal section; belongs to the glycosyltransferase 51 family.
messages: Membrane

216142:LT40 RS07895
gene id: 216142:LT40_RS07895
uniprot id: A0A089YSI4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

216142:LT40 RS18325
gene id: 216142:LT40_RS18325
uniprot id: A0A089YXW9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

216142:LT40 RS13995
gene id: 216142:LT40_RS13995
uniprot id: A0A089ZQZ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine-cytosine permease (2.A.39) family.
messages: Membrane

216142:LT40 RS14875
gene id: 216142:LT40_RS14875
uniprot id: A0A089YYS8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

216142:LT40 RS11300
gene id: 216142:LT40_RS11300
uniprot id: A0A089YW73
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ClpS family.
messages: Binds to the N-terminal domain of the chaperone ClpA.
messages: Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation.

216142:LT40 RS16715
gene id: 216142:LT40_RS16715
uniprot id: A0A089YZR7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

216142:LT40 RS18760
gene id: 216142:LT40_RS18760
uniprot id: A0A089YUX1
names: Subcellular Location Annotation
messages: Membrane

216142:LT40 RS12120
gene id: 216142:LT40_RS12120
uniprot id: A0A089YR71
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

216142:LT40 RS04700
gene id: 216142:LT40_RS04700
uniprot id: A0A089YMF7
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

216142:LT40 RS00180
gene id: 216142:LT40_RS00180
uniprot id: A0A089ZPH8
names: Similarity
messages: Belongs to the SAICAR synthetase family.

216142:LT40 RS02725
gene id: 216142:LT40_RS02725
uniprot id: A0A089YJ59
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

216142:LT40 RS08940
gene id: 216142:LT40_RS08940
uniprot id: A0A089YPM2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

216142:LT40 RS17250
gene id: 216142:LT40_RS17250
uniprot id: A0A089YTZ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inositol monophosphatase superfamily. CysQ family.
messages: Cell inner membrane
messages: Converts adenosine-3',5'-bisphosphate (PAP) to AMP.

216142:LT40 RS01700
gene id: 216142:LT40_RS01700
uniprot id: A0A089YIG1
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 104 family.
messages: Protein-arginine rhamnosyltransferase that catalyzes the transfer of a single rhamnose to elongation factor P (EF-P) on 'Lys-32', a modification required for EF-P-dependent rescue of polyproline stalled ribosomes.

216142:LT40 RS17580
gene id: 216142:LT40_RS17580
uniprot id: A0A089YRT4
names: Function
names: Similarity
names: Subunit
messages: Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division.
messages: Belongs to the ZapA family. Type 1 subfamily.
messages: Homodimer. Interacts with FtsZ.

216142:LT40 RS19770
gene id: 216142:LT40_RS19770
uniprot id: A0A089YVB9
names: Subcellular Location Annotation
messages: Membrane

216142:LT40 RS06435
gene id: 216142:LT40_RS06435
uniprot id: A0A089YRQ8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SelU family.
messages: Involved in the post-transcriptional modification of the uridine at the wobble position (U34) of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Catalyzes the conversion of 2-thiouridine (S2U-RNA) to 2-selenouridine (Se2U-RNA). Acts in a two-step process involving geranylation of 2-thiouridine (S2U) to S-geranyl-2-thiouridine (geS2U) and subsequent selenation of the latter derivative to 2-selenouridine (Se2U) in the tRNA chain.
messages: Monomer.

216142:LT40 RS00450
gene id: 216142:LT40_RS00450
uniprot id: A0A089YK65
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamA family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

216142:LT40 RS06670
gene id: 216142:LT40_RS06670
uniprot id: A0A089YNG4
names: Similarity
messages: Belongs to the peptidase C40 family.

216142:LT40 RS12245
gene id: 216142:LT40_RS12245
uniprot id: A0A089ZQS8
names: Function
names: Similarity
messages: Belongs to the class-I DAHP synthase family.
messages: Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP).

216142:LT40 RS11330
gene id: 216142:LT40_RS11330
uniprot id: A0A089ZQP4
names: Function
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
messages: Catalyzes two reactions in de novo purine nucleotide biosynthesis. Catalyzes the breakdown of 5-aminoimidazole- (N-succinylocarboxamide) ribotide (SAICAR or 2-[5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamido]succinate) to 5-aminoimidazole-4-carboxamide ribotide (AICAR or 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide) and fumarate, and of adenylosuccinate (ADS or N(6)-(1,2-dicarboxyethyl)-AMP) to adenosine monophosphate (AMP) and fumarate.

216142:LT40 RS05000
gene id: 216142:LT40_RS05000
uniprot id: A0A089ZQ10
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the QueC family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).

216142:LT40 RS01165
gene id: 216142:LT40_RS01165
uniprot id: A0A089ZPL4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

216142:LT40 RS20365
gene id: 216142:LT40_RS20365
uniprot id: A0A089ZRN2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerD subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

216142:LT40 RS05830
gene id: 216142:LT40_RS05830
uniprot id: A0A089YN42
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Membrane

216142:LT40 RS10725
gene id: 216142:LT40_RS10725
uniprot id: A0A089YNB3
names: Function
names: Similarity
messages: Belongs to the BCKDHA family.
messages: The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3).

216142:LT40 RS08165
gene id: 216142:LT40_RS08165
uniprot id: A0A089YSQ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

216142:LT40 RS16165
gene id: 216142:LT40_RS16165
uniprot id: A0A089ZR74
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

216142:LT40 RS10545
gene id: 216142:LT40_RS10545
uniprot id: A0A089ZQL5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

216142:LT40 RS18835
gene id: 216142:LT40_RS18835
uniprot id: A0A089YUY3
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LipB family.
messages: Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
messages: Cytoplasm
messages: In the reaction, the free carboxyl group of octanoic acid is attached via an amide linkage to the epsilon-amino group of a specific lysine residue of lipoyl domains of lipoate-dependent enzymes.

216142:LT40 RS19450
gene id: 216142:LT40_RS19450
uniprot id: A0A089YV76
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

216142:LT40 RS06030
gene id: 216142:LT40_RS06030
uniprot id: A0A089YKU4
names: Cofactor
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.
messages: Binds 1 [4Fe-4S] cluster per subunit.

216142:LT40 RS03615
gene id: 216142:LT40_RS03615
uniprot id: A0A089ZPV6
names: Similarity
messages: Belongs to the bacterial solute-binding protein 5 family.

216142:LT40 RS08310
gene id: 216142:LT40_RS08310
uniprot id: A0A089YUP7
names: Similarity
messages: Belongs to the lysine N(6)-hydroxylase/L-ornithine N(5)-oxygenase family.

216142:LT40 RS19760
gene id: 216142:LT40_RS19760
uniprot id: A0A089YYM6
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family.

216142:LT40 RS08295
gene id: 216142:LT40_RS08295
uniprot id: A0A089YSS9
names: Subcellular Location Annotation
messages: Membrane

216142:LT40 RS05435
gene id: 216142:LT40_RS05435
uniprot id: A0A089YKL6
names: Subcellular Location Annotation
messages: Membrane

216142:LT40 RS16345
gene id: 216142:LT40_RS16345
uniprot id: A0A089ZR81
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

216142:LT40 RS19050
gene id: 216142:LT40_RS19050
uniprot id: A0A089ZRI3
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

216142:LT40 RS18475
gene id: 216142:LT40_RS18475
uniprot id: A0A089YXZ6
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

216142:LT40 RS09575
gene id: 216142:LT40_RS09575
uniprot id: A0A089YML7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial microcompartment
messages: Belongs to the EutC family.
messages: Binds between the large and small subunits.
messages: Catalyzes the deamination of various vicinal amino-alcohols to oxo compounds. Allows this organism to utilize ethanolamine as the sole source of nitrogen and carbon in the presence of external vitamin B12.
messages: The basic unit is a heterodimer which dimerizes to form tetramers. The heterotetramers trimerize; 6 large subunits form a core ring with 6 small subunits projecting outwards.

216142:LT40 RS14150
gene id: 216142:LT40_RS14150
uniprot id: A0A089ZQZ9
names: Function
names: Similarity
messages: Belongs to the PurU family.
messages: Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).

216142:LT40 RS06360
gene id: 216142:LT40_RS06360
uniprot id: A0A089YL00
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

216142:LT40 RS20580
gene id: 216142:LT40_RS20580
uniprot id: A0A089ZRP0
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPAT/DAPAT family.
messages: Cell membrane
messages: The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate.

216142:LT40 RS03565
gene id: 216142:LT40_RS03565
uniprot id: A0A089ZPV4
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

216142:LT40 RS00505
gene id: 216142:LT40_RS00505
uniprot id: A0A089YQK6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KdsA family.
messages: Cytoplasm

216142:LT40 RS18375
gene id: 216142:LT40_RS18375
uniprot id: A0A089YXY1
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

216142:LT40 RS13740
gene id: 216142:LT40_RS13740
uniprot id: A0A089YS58
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein bS6.

216142:LT40 RS07390
gene id: 216142:LT40_RS07390
uniprot id: A0A089YU57
names: Subcellular Location Annotation
messages: Membrane

216142:LT40 RS05470
gene id: 216142:LT40_RS05470
uniprot id: A0A089YMY8
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

216142:LT40 RS01945
gene id: 216142:LT40_RS01945
uniprot id: A0A089ZPP3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RlmKL family.
messages: Cytoplasm
messages: Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA.

216142:LT40 RS01055
gene id: 216142:LT40_RS01055
uniprot id: A0A089YNZ0
names: Function
names: PTM
names: Similarity
messages: Acetylated. Deacetylation by the SIR2-homolog deacetylase activates the enzyme.
messages: Belongs to the ATP-dependent AMP-binding enzyme family.
messages: Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.

216142:LT40 RS00060
gene id: 216142:LT40_RS00060
uniprot id: A0A089YNK5
names: Function
names: Subunit
messages: Adenylyltransferase that mediates the addition of adenosine 5'-monophosphate (AMP) to specific residues of target proteins.
messages: Homodimer.

216142:LT40 RS16530
gene id: 216142:LT40_RS16530
uniprot id: A0A089YRA9
names: Caution
names: Function
names: Similarity
messages: Belongs to the dUTPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

216142:LT40 RS01985
gene id: 216142:LT40_RS01985
uniprot id: A0A089YKW5
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

216142:LT40 RS02235
gene id: 216142:LT40_RS02235
uniprot id: A0A089YRF6
names: Subcellular Location Annotation
messages: Membrane

216142:LT40 RS03855
gene id: 216142:LT40_RS03855
uniprot id: A0A089YLY9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Lacks the C-terminal regulatory region which is replaced by HisZ.

216142:LT40 RS13730
gene id: 216142:LT40_RS13730
uniprot id: A0A089YVN2
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

216142:LT40 RS09065
gene id: 216142:LT40_RS09065
uniprot id: A0A089YMD6
names: Similarity
messages: Belongs to the phosphohexose mutase family.

216142:LT40 RS19440
gene id: 216142:LT40_RS19440
uniprot id: A0A089YYI0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurJ/MviN family.
messages: Cell inner membrane
messages: Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.
messages: Membrane

216142:LT40 RS14930
gene id: 216142:LT40_RS14930
uniprot id: A0A089YYT8
names: Subcellular Location Annotation
messages: Membrane

216142:LT40 RS03055
gene id: 216142:LT40_RS03055
uniprot id: A0A089YQ06
names: Similarity
names: Subunit
messages: Belongs to the MoaE family.
messages: Heterotetramer of 2 MoaD subunits and 2 MoaE subunits. Also stable as homodimer. The enzyme changes between these two forms during catalysis.

216142:LT40 RS12045
gene id: 216142:LT40_RS12045
uniprot id: A0A089YR60
names: Function
names: Similarity
messages: Belongs to the Dus family. DusA subfamily.
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U20 and U20a in tRNAs.

216142:LT40 RS18830
gene id: 216142:LT40_RS18830
uniprot id: A0A089YSK8
names: Similarity
messages: Belongs to the UPF0250 family.

216142:LT40 RS18035
gene id: 216142:LT40_RS18035
uniprot id: A0A089Z0G1
names: Function
names: Similarity
messages: Belongs to the DHNA family.
messages: Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin.

216142:LT40 RS16025
gene id: 216142:LT40_RS16025
uniprot id: A0A089YQY7
names: Subcellular Location Annotation
messages: Membrane

216142:LT40 RS14680
gene id: 216142:LT40_RS14680
uniprot id: A0A089YQ83
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. SRP is a ribonucleoprotein composed of Ffh and a 4.5S RNA molecule.

216142:LT40 RS18160
gene id: 216142:LT40_RS18160
uniprot id: A0A089YUH9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate synthase component I family.
messages: Heterotetramer consisting of two non-identical subunits: a beta subunit (TrpG) and a large alpha subunit (TrpE).
messages: Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia.

216142:LT40 RS16375
gene id: 216142:LT40_RS16375
uniprot id: A0A089YX32
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

216142:LT40 RS13200
gene id: 216142:LT40_RS13200
uniprot id: A0A089ZQW3
names: Function
names: Similarity
names: Subunit
messages: A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild-type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity.
messages: Belongs to the RecC family.
messages: Heterotrimer of RecB, RecC and RecD. All subunits contribute to DNA-binding.

216142:LT40 RS09400
gene id: 216142:LT40_RS09400
uniprot id: A0A089YPT6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the glyoxalase I family.
messages: Binds 1 nickel ion per subunit.
messages: Binds 1 zinc ion per subunit. In the homodimer, two zinc ions are bound between subunits.
messages: Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione.

216142:LT40 RS03900
gene id: 216142:LT40_RS03900
uniprot id: A0A089YJP2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZapG family.
messages: Cell inner membrane
messages: Membrane

216142:LT40 RS02375
gene id: 216142:LT40_RS02375
uniprot id: A0A089YL52
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliS family.
messages: cytosol

216142:LT40 RS06700
gene id: 216142:LT40_RS06700
uniprot id: A0A089YTT7
names: Function
messages: Decarboxylates L-threonine-O-3-phosphate to yield (R)-1-amino-2-propanol O-2-phosphate, the precursor for the linkage between the nucleotide loop and the corrin ring in cobalamin.

216142:LT40 RS06440
gene id: 216142:LT40_RS06440
uniprot id: A0A089YL13
names: Subcellular Location Annotation
messages: Membrane

216142:LT40 RS05225
gene id: 216142:LT40_RS05225
uniprot id: A0A089YMR5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Membrane

216142:LT40 RS00750
gene id: 216142:LT40_RS00750
uniprot id: A0A089ZPJ9
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. TatD-type hydrolase family.

216142:LT40 RS13580
gene id: 216142:LT40_RS13580
uniprot id: A0A089YVK9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the urease beta subunit family.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

216142:LT40 RS18390
gene id: 216142:LT40_RS18390
uniprot id: A0A089Z0M8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

216142:LT40 RS12735
gene id: 216142:LT40_RS12735
uniprot id: A0A089YWV8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

216142:LT40 RS05390
gene id: 216142:LT40_RS05390
uniprot id: A0A089YMX4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.

216142:LT40 RS01130
gene id: 216142:LT40_RS01130
uniprot id: A0A089YP03
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

216142:LT40 RS19890
gene id: 216142:LT40_RS19890
uniprot id: A0A089YYP9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferrochelatase family.
messages: Catalyzes the ferrous insertion into protoporphyrin IX.
messages: Cytoplasm

216142:LT40 RS17800
gene id: 216142:LT40_RS17800
uniprot id: A0A089YUA3
names: Function
names: Similarity
names: Subunit
messages: Catalyzes the ADP transfer from ATP to D-glycero-beta-D-manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose.
messages: Catalyzes the phosphorylation of D-glycero-D-manno-heptose 7-phosphate at the C-1 position to selectively form D-glycero-beta-D-manno-heptose-1,7-bisphosphate.
messages: Homodimer.
messages: In the C-terminal section; belongs to the cytidylyltransferase family.
messages: In the N-terminal section; belongs to the carbohydrate kinase PfkB family.

216142:LT40 RS05535
gene id: 216142:LT40_RS05535
uniprot id: A0A089YRC3
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.

216142:LT40 RS20495
gene id: 216142:LT40_RS20495
uniprot id: A0A089YVQ0
names: Similarity
messages: Belongs to the peptidase S33 family.

216142:LT40 RS01255
gene id: 216142:LT40_RS01255
uniprot id: A0A089YKH9
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family.
messages: Homopolymer.

216142:LT40 RS14885
gene id: 216142:LT40_RS14885
uniprot id: A0A089YW66
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

216142:LT40 RS18860
gene id: 216142:LT40_RS18860
uniprot id: A0A089YUY9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptE lipoprotein family.
messages: Cell outer membrane
messages: Component of the lipopolysaccharide transport and assembly complex. Interacts with LptD.
messages: Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane.

216142:LT40 RS16605
gene id: 216142:LT40_RS16605
uniprot id: A0A089YRC1
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

216142:LT40 RS18215
gene id: 216142:LT40_RS18215
uniprot id: A0A089Z0J9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

216142:LT40 RS08280
gene id: 216142:LT40_RS08280
uniprot id: A0A089YPD9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

216142:LT40 RS00735
gene id: 216142:LT40_RS00735
uniprot id: A0A089YHZ8
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

216142:LT40 RS12725
gene id: 216142:LT40_RS12725
uniprot id: A0A089YP67
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MsrQ family.
messages: Binds 1 FMN per subunit.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.
messages: Cell membrane
messages: Heterodimer of a catalytic subunit (MsrP) and a heme-binding subunit (MsrQ).
messages: Membrane
messages: Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain.

216142:LT40 RS18445
gene id: 216142:LT40_RS18445
uniprot id: A0A089ZRG0
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

216142:LT40 RS02565
gene id: 216142:LT40_RS02565
uniprot id: A0A089YPQ4
names: Similarity
messages: Belongs to the type III secretion exporter family.

216142:LT40 RS14310
gene id: 216142:LT40_RS14310
uniprot id: A0A089YVW7
names: Function
names: Similarity
messages: Belongs to the ABC1 family. UbiB subfamily.
messages: Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis.

216142:LT40 RS12565
gene id: 216142:LT40_RS12565
uniprot id: A0A089ZQU0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

216142:LT40 RS10285
gene id: 216142:LT40_RS10285
uniprot id: A0A089YQA5
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

216142:LT40 RS03860
gene id: 216142:LT40_RS03860
uniprot id: A0A089YSC3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.

216142:LT40 RS17420
gene id: 216142:LT40_RS17420
uniprot id: A0A089YRQ9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aldehyde dehydrogenase family.
messages: Binds 2 potassium ions per subunit.
messages: Dimer of dimers.
messages: Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the irreversible oxidation of betaine aldehyde to the corresponding acid.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

216142:LT40 RS14565
gene id: 216142:LT40_RS14565
uniprot id: A0A089ZR15
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

216142:LT40 RS12965
gene id: 216142:LT40_RS12965
uniprot id: A0A089YRN5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

216142:LT40 RS14205
gene id: 216142:LT40_RS14205
uniprot id: A0A089ZR01
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
messages: Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).
messages: Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
messages: Cytoplasm

216142:LT40 RS05320
gene id: 216142:LT40_RS05320
uniprot id: A0A089YKJ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm

216142:LT40 RS03890
gene id: 216142:LT40_RS03890
uniprot id: A0A089ZPW7
names: Caution
names: Function
names: Similarity
names: Subunit
messages: APS kinase catalyzes the synthesis of activated sulfate.
messages: Belongs to the APS kinase family.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.
messages: Catalyzes the synthesis of activated sulfate.
messages: Heterodimer composed of CysD, the smaller subunit, and CysN.
messages: In the C-terminal section; belongs to the APS kinase family.
messages: In the N-terminal section; belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: With CysD forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway. APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD.

216142:LT40 RS13810
gene id: 216142:LT40_RS13810
uniprot id: A0A089ZQY6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Hfq family.
messages: Homohexamer.
messages: RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs.

216142:LT40 RS00275
gene id: 216142:LT40_RS00275
uniprot id: A0A089YQH6
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

216142:LT40 RS00525
gene id: 216142:LT40_RS00525
uniprot id: A0A089YK77
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

216142:LT40 RS05350
gene id: 216142:LT40_RS05350
uniprot id: A0A089YMW8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
messages: Homodimer.

216142:LT40 RS16420
gene id: 216142:LT40_RS16420
uniprot id: A0A089ZR84
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the rubredoxin family.
messages: Binds 1 Fe(3+) ion per subunit.
messages: Cytoplasm

216142:LT40 RS15775
gene id: 216142:LT40_RS15775
uniprot id: A0A089YT49
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family. GlucD subfamily.

216142:LT40 RS07850
gene id: 216142:LT40_RS07850
uniprot id: A0A089YP34
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

216142:LT40 RS17235
gene id: 216142:LT40_RS17235
uniprot id: A0A089ZRB6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

216142:LT40 RS15015
gene id: 216142:LT40_RS15015
uniprot id: A0A089YW85
names: Similarity
messages: Belongs to the UPF0339 family. Duplicated subfamily.

216142:LT40 RS06320
gene id: 216142:LT40_RS06320
uniprot id: A0A089ZQ58
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

216142:LT40 RS08120
gene id: 216142:LT40_RS08120
uniprot id: A0A089YLZ6
names: Caution
names: Function
names: Similarity
messages: Belongs to the globin family.
messages: In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
messages: Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

216142:LT40 RS16320
gene id: 216142:LT40_RS16320
uniprot id: A0A089ZR80
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

216142:LT40 RS05820
gene id: 216142:LT40_RS05820
uniprot id: A0A089YRG6
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

216142:LT40 RS09110
gene id: 216142:LT40_RS09110
uniprot id: A0A089ZQG2
names: Subcellular Location Annotation
messages: Membrane

216142:LT40 RS16835
gene id: 216142:LT40_RS16835
uniprot id: A0A089YRF9
names: Function
names: PTM
names: Similarity
messages: An intermediate of this reaction is the autophosphorylated ppk in which a phosphate is covalently linked to a histidine residue through a N-P bond.
messages: Belongs to the polyphosphate kinase 1 (PPK1) family.
messages: Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP).

216142:LT40 RS09915
gene id: 216142:LT40_RS09915
uniprot id: A0A089YVF1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

216142:LT40 RS20535
gene id: 216142:LT40_RS20535
uniprot id: A0A089YYZ5
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

216142:LT40 RS19435
gene id: 216142:LT40_RS19435
uniprot id: A0A089ZRJ8
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

216142:LT40 RS00285
gene id: 216142:LT40_RS00285
uniprot id: A0A089YNN2
names: Similarity
messages: Belongs to the leucine-binding protein family.

216142:LT40 RS00415
gene id: 216142:LT40_RS00415
uniprot id: A0A089YNP8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

216142:LT40 RS12800
gene id: 216142:LT40_RS12800
uniprot id: A0A089YP79
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. GluQ subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5-dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon.

216142:LT40 RS07290
gene id: 216142:LT40_RS07290
uniprot id: A0A089ZQ94
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

216142:LT40 RS03145
gene id: 216142:LT40_RS03145
uniprot id: A0A089YRZ6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptF/LptG family.
messages: Component of the lipopolysaccharide transport and assembly complex. The LptBFG transporter is composed of two ATP-binding proteins (LptB) and two transmembrane proteins (LptF and LptG).
messages: Membrane
messages: Part of the ABC transporter complex LptBFG involved in the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane.

216142:LT40 RS07005
gene id: 216142:LT40_RS07005
uniprot id: A0A089YNL7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

216142:LT40 RS14890
gene id: 216142:LT40_RS14890
uniprot id: A0A089YQB3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

216142:LT40 RS06965
gene id: 216142:LT40_RS06965
uniprot id: A0A089ZQ82
names: Subcellular Location Annotation
messages: Membrane

216142:LT40 RS06640
gene id: 216142:LT40_RS06640
uniprot id: A0A089YL42
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.

216142:LT40 RS19040
gene id: 216142:LT40_RS19040
uniprot id: A0A089YV16
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

216142:LT40 RS00995
gene id: 216142:LT40_RS00995
uniprot id: A0A089YI44
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

216142:LT40 RS04615
gene id: 216142:LT40_RS04615
uniprot id: A0A089YQS3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RseB family.
messages: Periplasm

216142:LT40 RS05790
gene id: 216142:LT40_RS05790
uniprot id: A0A089ZQ38
names: Similarity
messages: Belongs to the YciI family.

216142:LT40 RS13405
gene id: 216142:LT40_RS13405
uniprot id: A0A089YVH3
names: Subcellular Location Annotation
messages: Membrane

216142:LT40 RS15050
gene id: 216142:LT40_RS15050
uniprot id: A0A089YW90
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

216142:LT40 RS11360
gene id: 216142:LT40_RS11360
uniprot id: A0A089YUD0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 20 kDa subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Cell membrane
messages: NDH-1 is composed of 13 different subunits. Subunits NuoB, CD, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

216142:LT40 RS15395
gene id: 216142:LT40_RS15395
uniprot id: A0A089YSY0
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

216142:LT40 RS14195
gene id: 216142:LT40_RS14195
uniprot id: A0A089YSC8
names: Similarity
messages: Belongs to the glutamate synthase family.

216142:LT40 RS00545
gene id: 216142:LT40_RS00545
uniprot id: A0A089YHX2
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruD family.
messages: Responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs.

216142:LT40 RS08290
gene id: 216142:LT40_RS08290
uniprot id: A0A089ZQD1
names: Subcellular Location Annotation
messages: Membrane

216142:LT40 RS05555
gene id: 216142:LT40_RS05555
uniprot id: A0A089ZQ29
names: Similarity
messages: Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily.

216142:LT40 RS16000
gene id: 216142:LT40_RS16000
uniprot id: A0A089YQY0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gmhB family.
messages: Cytoplasm

216142:LT40 RS07135
gene id: 216142:LT40_RS07135
uniprot id: A0A089YS18
names: Similarity
messages: Belongs to the DapA family.

216142:LT40 RS03395
gene id: 216142:LT40_RS03395
uniprot id: A0A089YJE8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

216142:LT40 RS17620
gene id: 216142:LT40_RS17620
uniprot id: A0A089ZRD1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

216142:LT40 RS16020
gene id: 216142:LT40_RS16020
uniprot id: A0A089YWV0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

216142:LT40 RS02200
gene id: 216142:LT40_RS02200
uniprot id: A0A089YIR8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

216142:LT40 RS15190
gene id: 216142:LT40_RS15190
uniprot id: A0A089YST8
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

216142:LT40 RS14585
gene id: 216142:LT40_RS14585
uniprot id: A0A089YYM7
names: Subcellular Location Annotation
messages: Membrane

216142:LT40 RS05825
gene id: 216142:LT40_RS05825
uniprot id: A0A089YKR6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

216142:LT40 RS18625
gene id: 216142:LT40_RS18625
uniprot id: A0A089ZRG7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

216142:LT40 RS20100
gene id: 216142:LT40_RS20100
uniprot id: A0A089YYT6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PsiE family.
messages: Cell inner membrane
messages: Membrane

216142:LT40 RS13785
gene id: 216142:LT40_RS13785
uniprot id: A0A089ZQY5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

216142:LT40 RS06055
gene id: 216142:LT40_RS06055
uniprot id: A0A089YKV1
names: Function
names: Similarity
messages: Belongs to the nucleoside phosphorylase PpnP family.
messages: Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions.

216142:LT40 RS03380
gene id: 216142:LT40_RS03380
uniprot id: A0A089ZPU7
names: Subcellular Location Annotation
messages: Membrane

216142:LT40 RS09175
gene id: 216142:LT40_RS09175
uniprot id: A0A089ZQG4
names: Subcellular Location Annotation
messages: Membrane

216142:LT40 RS03490
gene id: 216142:LT40_RS03490
uniprot id: A0A089ZPV1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.
messages: Cytoplasm
messages: Homodimer. Forms a heterotetramer with IscU, interacts with other sulfur acceptors.
messages: Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins.

216142:LT40 RS17970
gene id: 216142:LT40_RS17970
uniprot id: A0A089YUD8
names: Similarity
messages: Belongs to the HipA Ser/Thr kinase family.

216142:LT40 RS16250
gene id: 216142:LT40_RS16250
uniprot id: A0A089YX12
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

216142:LT40 RS14345
gene id: 216142:LT40_RS14345
uniprot id: A0A089YSF3
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

216142:LT40 RS19460
gene id: 216142:LT40_RS19460
uniprot id: A0A089ZRJ9
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

216142:LT40 RS07235
gene id: 216142:LT40_RS07235
uniprot id: A0A089YU26
names: Similarity
messages: Belongs to the mannose-6-phosphate isomerase type 2 family.

216142:LT40 RS07165
gene id: 216142:LT40_RS07165
uniprot id: A0A089YS25
names: Similarity
messages: Belongs to the EndA/NucM nuclease family.

216142:LT40 RS09310
gene id: 216142:LT40_RS09310
uniprot id: A0A089ZQG9
names: Similarity
messages: Belongs to the EfeM/EfeO family.

216142:LT40 RS19075
gene id: 216142:LT40_RS19075
uniprot id: A0A089ZRI4
names: Function
names: Similarity
messages: Belongs to the isochorismatase family. RutB subfamily.
messages: Hydrolyzes ureidoacrylate to form aminoacrylate and carbamate. The carbamate hydrolyzes spontaneously, thereby releasing one of the nitrogen atoms of the pyrimidine ring as ammonia and one of its carbon atoms as CO2.

216142:LT40 RS02095
gene id: 216142:LT40_RS02095
uniprot id: A0A089YPG6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

216142:LT40 RS00575
gene id: 216142:LT40_RS00575
uniprot id: A0A089YK86
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.
messages: This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.

216142:LT40 RS18130
gene id: 216142:LT40_RS18130
uniprot id: A0A089YS34
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family.
messages: Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system.
messages: The complex is composed of two ATP-binding proteins (PotA), two transmembrane proteins (PotB and PotC) and a solute-binding protein (PotD).

216142:LT40 RS07420
gene id: 216142:LT40_RS07420
uniprot id: A0A089ZQ99
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

216142:LT40 RS04075
gene id: 216142:LT40_RS04075
uniprot id: A0A089ZPX4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.
messages: Cell membrane
messages: Self-interacts. Interacts with FtsZ.

216142:LT40 RS13335
gene id: 216142:LT40_RS13335
uniprot id: A0A089YPJ8
names: Similarity
messages: Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family.

216142:LT40 RS11285
gene id: 216142:LT40_RS11285
uniprot id: A0A089YNI2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the R-transferase family. Bpt subfamily.
messages: Cytoplasm
messages: Functions in the N-end rule pathway of protein degradation where it conjugates Leu from its aminoacyl-tRNA to the N-termini of proteins containing an N-terminal aspartate or glutamate.

216142:LT40 RS20240
gene id: 216142:LT40_RS20240
uniprot id: A0A089YT83
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

216142:LT40 RS10925
gene id: 216142:LT40_RS10925
uniprot id: A0A089YU64
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell outer membrane

216142:LT40 RS14095
gene id: 216142:LT40_RS14095
uniprot id: A0A089YYD9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EamA transporter family.
messages: Membrane

216142:LT40 RS07200
gene id: 216142:LT40_RS07200
uniprot id: A0A089YLD3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ElaB/YgaM/YqjD family.
messages: Cell inner membrane
messages: Membrane

216142:LT40 RS07400
gene id: 216142:LT40_RS07400
uniprot id: A0A089YS82
names: Similarity
messages: Belongs to the N-acylglucosamine 2-epimerase family.

216142:LT40 RS13420
gene id: 216142:LT40_RS13420
uniprot id: A0A089YXC1
names: Similarity
messages: Belongs to the SUI1 family.

216142:LT40 RS19080
gene id: 216142:LT40_RS19080
uniprot id: A0A089YYB7
names: Function
names: Similarity
messages: Belongs to the RutC family.
messages: Involved in pyrimidine catabolism. Catalyzes the deamination of 3-aminoacrylate to malonic semialdehyde, a reaction that can also occur spontaneously. RutC may facilitate the reaction and modulate the metabolic fitness, rather than catalyzing essential functions.

216142:LT40 RS05655
gene id: 216142:LT40_RS05655
uniprot id: A0A089YTB7
names: Similarity
messages: Belongs to the WrbA family.

216142:LT40 RS02335
gene id: 216142:LT40_RS02335
uniprot id: A0A089ZPQ7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
messages: Bacterial flagellum basal body
messages: Belongs to the FlgI family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod.

216142:LT40 RS10945
gene id: 216142:LT40_RS10945
uniprot id: A0A089ZQM9
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the peroxiredoxin family. Tpx subfamily.
messages: Homodimer.
messages: The active site is a conserved redox-active cysteine residue, the peroxidatic cysteine (C(P)), which makes the nucleophilic attack on the peroxide substrate. The peroxide oxidizes the C(P)-SH to cysteine sulfenic acid (C(P)-SOH), which then reacts with another cysteine residue, the resolving cysteine (C(R)), to form a disulfide bridge. The disulfide is subsequently reduced by an appropriate electron donor to complete the catalytic cycle. In this atypical 2-Cys peroxiredoxin, C(R) is present in the same subunit to form an intramolecular disulfide. The disulfide is subsequently reduced by thioredoxin.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

216142:LT40 RS03710
gene id: 216142:LT40_RS03710
uniprot id: A0A089YS96
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MreD family.
messages: Cell inner membrane
messages: Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins.
messages: Membrane

216142:LT40 RS16985
gene id: 216142:LT40_RS16985
uniprot id: A0A089YXC5
names: Similarity
messages: Belongs to the outer membrane porin (Opr) (TC 1.B.25) family.

216142:LT40 RS20735
gene id: 216142:LT40_RS20735
uniprot id: A0A089ZRP6
names: Similarity
messages: Belongs to the CvfB family.

216142:LT40 RS03155
gene id: 216142:LT40_RS03155
uniprot id: A0A089YQ22
names: Subcellular Location Annotation
messages: Cytoplasm

216142:LT40 RS00140
gene id: 216142:LT40_RS00140
uniprot id: A0A089YHS1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48 family. BepA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Functions as both a chaperone and a metalloprotease. Maintains the integrity of the outer membrane by promoting either the assembly or the elimination of outer membrane proteins, depending on their folding state.
messages: Periplasm

216142:LT40 RS02855
gene id: 216142:LT40_RS02855
uniprot id: A0A089YJ78
names: Subcellular Location Annotation
messages: Membrane

216142:LT40 RS16090
gene id: 216142:LT40_RS16090
uniprot id: A0A089ZR71
names: Subcellular Location Annotation
messages: Membrane

216142:LT40 RS06730
gene id: 216142:LT40_RS06730
uniprot id: A0A089ZQ73
names: Subcellular Location Annotation
messages: Membrane

216142:LT40 RS18080
gene id: 216142:LT40_RS18080
uniprot id: A0A089YUG0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

216142:LT40 RS10335
gene id: 216142:LT40_RS10335
uniprot id: A0A089YQB8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CopC family.
messages: Involved in copper resistance.
messages: Periplasm

216142:LT40 RS16550
gene id: 216142:LT40_RS16550
uniprot id: A0A089YX61
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

216142:LT40 RS18485
gene id: 216142:LT40_RS18485
uniprot id: A0A089YUN9
names: Function
names: Similarity
messages: Belongs to the catalase family.
messages: Decomposes hydrogen peroxide into water and oxygen; serves to protect cells from the toxic effects of hydrogen peroxide.

216142:LT40 RS13585
gene id: 216142:LT40_RS13585
uniprot id: A0A089YPS5
names: Cofactor
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family.
messages: Binds 2 nickel ions per subunit.
messages: Carbamylation allows a single lysine to coordinate two nickel ions.
messages: Carboxylation allows a single lysine to coordinate two nickel ions.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

216142:LT40 RS16010
gene id: 216142:LT40_RS16010
uniprot id: A0A089YZE2
names: Subcellular Location Annotation
messages: Membrane

216142:LT40 RS18600
gene id: 216142:LT40_RS18600
uniprot id: A0A089YY13
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG).

216142:LT40 RS14185
gene id: 216142:LT40_RS14185
uniprot id: A0A089YVU7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the threonine aldolase family.
messages: Catalyzes the cleavage of L-allo-threonine and L-threonine to glycine and acetaldehyde.
messages: Homotetramer.

216142:LT40 RS04625
gene id: 216142:LT40_RS04625
uniprot id: A0A089YMD8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

216142:LT40 RS11465
gene id: 216142:LT40_RS11465
uniprot id: A0A089YUE6
names: Similarity
messages: Belongs to the radical SAM superfamily. Anaerobic sulfatase-maturating enzyme family.

216142:LT40 RS18085
gene id: 216142:LT40_RS18085
uniprot id: A0A089Z0H3
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PdxA family.
messages: Binds 1 divalent metal cation per subunit. Can use ions such as Zn(2+), Mg(2+) or Co(2+).
messages: Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L-threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP).
messages: Cytoplasm
messages: Homodimer.
messages: The active site is located at the dimer interface.

216142:LT40 RS12995
gene id: 216142:LT40_RS12995
uniprot id: A0A089YX16
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamE family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

216142:LT40 RS14740
gene id: 216142:LT40_RS14740
uniprot id: A0A089YSL1
names: Subcellular Location Annotation
messages: Membrane

216142:LT40 RS13655
gene id: 216142:LT40_RS13655
uniprot id: A0A089YVM1
names: Similarity
messages: Belongs to the N-acylglucosamine 2-epimerase family.

216142:LT40 RS06760
gene id: 216142:LT40_RS06760
uniprot id: A0A089YRV1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

216142:LT40 RS04065
gene id: 216142:LT40_RS04065
uniprot id: A0A089YM24
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

216142:LT40 RS00065
gene id: 216142:LT40_RS00065
uniprot id: A0A089YHR0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.
messages: Binds 2 iron ions per subunit.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

216142:LT40 RS12445
gene id: 216142:LT40_RS12445
uniprot id: A0A089YRD3
names: Subcellular Location Annotation
messages: Membrane

216142:LT40 RS03750
gene id: 216142:LT40_RS03750
uniprot id: A0A089YJL4
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.
messages: There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors.

216142:LT40 RS19400
gene id: 216142:LT40_RS19400
uniprot id: A0A089YV68
names: Similarity
messages: Belongs to the YjdM family.

216142:LT40 RS16195
gene id: 216142:LT40_RS16195
uniprot id: A0A089ZR75
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phospholipase D family. Cardiolipin synthase subfamily. ClsA sub-subfamily.
messages: Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol.
messages: Cell membrane
messages: Membrane

216142:LT40 RS17930
gene id: 216142:LT40_RS17930
uniprot id: A0A089YXQ4
names: Subcellular Location Annotation
messages: Membrane

216142:LT40 RS17400
gene id: 216142:LT40_RS17400
uniprot id: A0A089YU20
names: Subcellular Location Annotation
messages: Membrane

216142:LT40 RS05795
gene id: 216142:LT40_RS05795
uniprot id: A0A089YRG1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YciB family.
messages: Cell inner membrane
messages: Plays a role in cell envelope biogenesis, maintenance of cell envelope integrity and membrane homeostasis.

216142:LT40 RS18360
gene id: 216142:LT40_RS18360
uniprot id: A0A089YUK9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

216142:LT40 RS13795
gene id: 216142:LT40_RS13795
uniprot id: A0A089YPU9
names: Function
names: Similarity
messages: Belongs to the band 7/mec-2 family. HflC subfamily.
messages: HflC and HflK could regulate a protease.

216142:LT40 RS10400
gene id: 216142:LT40_RS10400
uniprot id: A0A089YVQ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

216142:LT40 RS01870
gene id: 216142:LT40_RS01870
uniprot id: A0A089ZPP0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAPS reductase family. CysH subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of sulfite from adenosine 5'-phosphosulfate (APS) using thioredoxin as an electron donor.
messages: Cytoplasm

216142:LT40 RS19465
gene id: 216142:LT40_RS19465
uniprot id: A0A089YYI4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

216142:LT40 RS09270
gene id: 216142:LT40_RS09270
uniprot id: A0A089YMG6
names: Similarity
messages: Belongs to the KHG/KDPG aldolase family.

216142:LT40 RS08995
gene id: 216142:LT40_RS08995
uniprot id: A0A089YUY5
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

216142:LT40 RS13805
gene id: 216142:LT40_RS13805
uniprot id: A0A089YY88
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

216142:LT40 RS03200
gene id: 216142:LT40_RS03200
uniprot id: A0A089ZPU0
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

216142:LT40 RS06090
gene id: 216142:LT40_RS06090
uniprot id: A0A089YTI5
names: Function
names: Similarity
messages: Belongs to the TrhO family.
messages: Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs.

216142:LT40 RS09190
gene id: 216142:LT40_RS09190
uniprot id: A0A089YPQ7
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. GDP-mannose 4,6-dehydratase subfamily.
messages: Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6-deoxy-D-mannose.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

216142:LT40 RS09595
gene id: 216142:LT40_RS09595
uniprot id: A0A089YTD7
names: Similarity
messages: Belongs to the DNA polymerase type-Y family.

216142:LT40 RS12740
gene id: 216142:LT40_RS12740
uniprot id: A0A089ZQU6
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

216142:LT40 RS17850
gene id: 216142:LT40_RS17850
uniprot id: A0A089YUB5
names: Function
names: Similarity
messages: Belongs to the PqqC family.
messages: Ring cyclization and eight-electron oxidation of 3a-(2-amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline-7,9-dicarboxylic-acid to PQQ.

216142:LT40 RS04920
gene id: 216142:LT40_RS04920
uniprot id: A0A089YSY1
names: Similarity
messages: Belongs to the Dps family.

216142:LT40 RS07310
gene id: 216142:LT40_RS07310
uniprot id: A0A089YU40
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S24 family.
messages: Homodimer.
messages: Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.

216142:LT40 RS10940
gene id: 216142:LT40_RS10940
uniprot id: A0A089YW25
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

216142:LT40 RS13010
gene id: 216142:LT40_RS13010
uniprot id: A0A089YPC5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

216142:LT40 RS14045
gene id: 216142:LT40_RS14045
uniprot id: A0A089ZQZ5
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily.
messages: Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl-L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway.

216142:LT40 RS00150
gene id: 216142:LT40_RS00150
uniprot id: A0A089YQG2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

216142:LT40 RS06425
gene id: 216142:LT40_RS06425
uniprot id: A0A089YTP2
names: Similarity
messages: Belongs to the phosphate/phosphite/phosphonate binding protein family.

216142:LT40 RS15570
gene id: 216142:LT40_RS15570
uniprot id: A0A089YQL8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PNT beta subunit family.
messages: Cell inner membrane
messages: Heterodimer of an alpha and a beta chain.
messages: Membrane
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

216142:LT40 RS02175
gene id: 216142:LT40_RS02175
uniprot id: A0A089YIR3
names: Function
names: Subunit
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease.

216142:LT40 RS05730
gene id: 216142:LT40_RS05730
uniprot id: A0A089YN28
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

216142:LT40 RS13240
gene id: 216142:LT40_RS13240
uniprot id: A0A089YRS8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

216142:LT40 RS04790
gene id: 216142:LT40_RS04790
uniprot id: A0A089YSV1
names: Similarity
messages: Belongs to the peptidase M18 family.

216142:LT40 RS03235
gene id: 216142:LT40_RS03235
uniprot id: A0A089YJC5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

216142:LT40 RS12825
gene id: 216142:LT40_RS12825
uniprot id: A0A089YP83
names: Function
names: Similarity
messages: Belongs to the HPPK family.
messages: Catalyzes the transfer of pyrophosphate from adenosine triphosphate (ATP) to 6-hydroxymethyl-7,8-dihydropterin, an enzymatic step in folate biosynthesis pathway.

216142:LT40 RS13565
gene id: 216142:LT40_RS13565
uniprot id: A0A089YS31
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UreD family.
messages: Cytoplasm
messages: Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
messages: UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

216142:LT40 RS05345
gene id: 216142:LT40_RS05345
uniprot id: A0A089YKK4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase T family.
messages: Binds two Mg(2+) per subunit. The active form of the enzyme binds two Mg(2+) ions in its active site. The first Mg(2+) forms only one salt bridge with the protein.
messages: Homodimer.
messages: Trims short 3' overhangs of a variety of RNA species, leaving a one or two nucleotide 3' overhang. Responsible for the end-turnover of tRNA: specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis.

216142:LT40 RS03415
gene id: 216142:LT40_RS03415
uniprot id: A0A089YQ60
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

216142:LT40 RS09700
gene id: 216142:LT40_RS09700
uniprot id: A0A089YTF7
names: Similarity
messages: Belongs to the Dps family.

216142:LT40 RS15310
gene id: 216142:LT40_RS15310
uniprot id: A0A089YQH5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

216142:LT40 RS16500
gene id: 216142:LT40_RS16500
uniprot id: A0A089YX51
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase PH family.
messages: Homohexameric ring arranged as a trimer of dimers.
messages: Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.

216142:LT40 RS01360
gene id: 216142:LT40_RS01360
uniprot id: A0A089YIA8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Membrane

216142:LT40 RS04860
gene id: 216142:LT40_RS04860
uniprot id: A0A089YMI4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
messages: Belongs to the KdsB family.
messages: Cytoplasm

216142:LT40 RS18825
gene id: 216142:LT40_RS18825
uniprot id: A0A089YY72
names: Function
names: Similarity
messages: Belongs to the peptidase S11 family.
messages: Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors.

216142:LT40 RS05265
gene id: 216142:LT40_RS05265
uniprot id: A0A089ZQ19
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.

216142:LT40 RS07010
gene id: 216142:LT40_RS07010
uniprot id: A0A089YTY9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

216142:LT40 RS01915
gene id: 216142:LT40_RS01915
uniprot id: A0A089YR87
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Membrane

216142:LT40 RS07515
gene id: 216142:LT40_RS07515
uniprot id: A0A089YU83
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

216142:LT40 RS20035
gene id: 216142:LT40_RS20035
uniprot id: A0A089YVF7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CysZ family.
messages: Cell inner membrane
messages: High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway.

216142:LT40 RS00465
gene id: 216142:LT40_RS00465
uniprot id: A0A089YNQ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioester dehydratase family. FabZ subfamily.
messages: Cytoplasm
messages: Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.

216142:LT40 RS14315
gene id: 216142:LT40_RS14315
uniprot id: A0A089YQ23
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PRA-CH family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.
messages: Cytoplasm
messages: Homodimer.

216142:LT40 RS08130
gene id: 216142:LT40_RS08130
uniprot id: A0A089YUM4
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

216142:LT40 RS03110
gene id: 216142:LT40_RS03110
uniprot id: A0A089YJA9
names: Similarity
names: Subunit
messages: Belongs to the bacterial histone-like protein family.
messages: Heterodimer of an alpha and a beta chain.

216142:LT40 RS14365
gene id: 216142:LT40_RS14365
uniprot id: A0A089YQ31
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family. OpgH subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs).
messages: Membrane

216142:LT40 RS12955
gene id: 216142:LT40_RS12955
uniprot id: A0A089YV63
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

216142:LT40 RS10475
gene id: 216142:LT40_RS10475
uniprot id: A0A089YQD8
names: Similarity
messages: Belongs to the NtaA/SnaA/DszA monooxygenase family.

216142:LT40 RS13415
gene id: 216142:LT40_RS13415
uniprot id: A0A089YRY1
names: Function
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. SpeA subfamily.
messages: Catalyzes the biosynthesis of agmatine from arginine.

216142:LT40 RS04305
gene id: 216142:LT40_RS04305
uniprot id: A0A089ZPY3
names: Subcellular Location Annotation
messages: Membrane

216142:LT40 RS13745
gene id: 216142:LT40_RS13745
uniprot id: A0A089YY79
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with bS18 to 16S ribosomal RNA.

216142:LT40 RS13130
gene id: 216142:LT40_RS13130
uniprot id: A0A089YVA2
names: Subcellular Location Annotation
messages: Membrane

216142:LT40 RS15665
gene id: 216142:LT40_RS15665
uniprot id: A0A089YWL6
names: Subcellular Location Annotation
messages: Membrane

216142:LT40 RS14015
gene id: 216142:LT40_RS14015
uniprot id: A0A089YYC4
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

216142:LT40 RS01460
gene id: 216142:LT40_RS01460
uniprot id: A0A089YR12
names: Function
names: Subunit
messages: Catalyzes the ketonization of 2-hydroxymuconate stereoselectively to yield 2-oxo-3-hexenedioate.
messages: Homohexamer.

216142:LT40 RS01895
gene id: 216142:LT40_RS01895
uniprot id: A0A089ZPP1
names: Function
names: Similarity
messages: Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PSRP subfamily.
messages: Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation/dephosphorylation.

216142:LT40 RS00890
gene id: 216142:LT40_RS00890
uniprot id: A0A089YKD1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SNF2/RAD54 helicase family. RapA subfamily.
messages: Interacts with the RNAP. Has a higher affinity for the core RNAP than for the holoenzyme. Its ATPase activity is stimulated by binding to RNAP.
messages: Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair.

216142:LT40 RS15480
gene id: 216142:LT40_RS15480
uniprot id: A0A089YWH9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
messages: Cell inner membrane

216142:LT40 RS06125
gene id: 216142:LT40_RS06125
uniprot id: A0A089YRL4
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily. UbiG/COQ3 family.
messages: O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway.

216142:LT40 RS06695
gene id: 216142:LT40_RS06695
uniprot id: A0A089YNG8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobD/CbiB family.
messages: Cell membrane
messages: Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

216142:LT40 RS07000
gene id: 216142:LT40_RS07000
uniprot id: A0A089YLA1
names: Similarity
messages: Belongs to the manganese catalase family.

216142:LT40 RS09280
gene id: 216142:LT40_RS09280
uniprot id: A0A089YV35
names: Subcellular Location Annotation
messages: Membrane

216142:LT40 RS03930
gene id: 216142:LT40_RS03930
uniprot id: A0A089YM02
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

216142:LT40 RS11205
gene id: 216142:LT40_RS11205
uniprot id: A0A089YUA8
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.

216142:LT40 RS18155
gene id: 216142:LT40_RS18155
uniprot id: A0A089YS41
names: Function
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family.
messages: Specifically catalyzes the dephosphorylation of 2-phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress.

216142:LT40 RS19090
gene id: 216142:LT40_RS19090
uniprot id: A0A089YV23
names: Function
names: Similarity
messages: Belongs to the non-flavoprotein flavin reductase family. RutF subfamily.
messages: Catalyzes the reduction of FMN to FMNH2 which is used to reduce pyrimidine by RutA via the Rut pathway.

216142:LT40 RS03310
gene id: 216142:LT40_RS03310
uniprot id: A0A089YJD5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DsbB family.
messages: Cell inner membrane
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein.

216142:LT40 RS15745
gene id: 216142:LT40_RS15745
uniprot id: A0A089YQR9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

216142:LT40 RS16505
gene id: 216142:LT40_RS16505
uniprot id: A0A089YRA5
names: Cofactor
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.
messages: Probably binds two magnesium or manganese ions per subunit.

216142:LT40 RS03915
gene id: 216142:LT40_RS03915
uniprot id: A0A089ZPW8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AFG1 ATPase family. ZapE subfamily.
messages: Cytoplasm
messages: Interacts with FtsZ.
messages: Reduces the stability of FtsZ polymers in the presence of ATP.

216142:LT40 RS02530
gene id: 216142:LT40_RS02530
uniprot id: A0A089YRM1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

216142:LT40 RS00460
gene id: 216142:LT40_RS00460
uniprot id: A0A089ZPI8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
messages: Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
messages: Homotrimer.

216142:LT40 RS05890
gene id: 216142:LT40_RS05890
uniprot id: A0A089YTE8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

216142:LT40 RS03140
gene id: 216142:LT40_RS03140
uniprot id: A0A089YLN2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptF/LptG family.
messages: Cell inner membrane
messages: Component of the lipopolysaccharide transport and assembly complex. The LptBFG transporter is composed of two ATP-binding proteins (LptB) and two transmembrane proteins (LptF and LptG).
messages: Membrane
messages: Part of the ABC transporter complex LptBFG involved in the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane.

216142:LT40 RS04380
gene id: 216142:LT40_RS04380
uniprot id: A0A089ZPY6
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

216142:LT40 RS07015
gene id: 216142:LT40_RS07015
uniprot id: A0A089ZQ84
names: Subcellular Location Annotation
messages: Membrane

216142:LT40 RS16870
gene id: 216142:LT40_RS16870
uniprot id: A0A089YZU7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.

216142:LT40 RS09315
gene id: 216142:LT40_RS09315
uniprot id: A0A089YT87
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the oxidase-dependent Fe transporter (OFeT) (TC 9.A.10.1) family.
messages: Membrane

216142:LT40 RS19190
gene id: 216142:LT40_RS19190
uniprot id: A0A089YV38
names: Similarity
messages: Belongs to the intradiol ring-cleavage dioxygenase family.

216142:LT40 RS06750
gene id: 216142:LT40_RS06750
uniprot id: A0A089YTU8
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

216142:LT40 RS18400
gene id: 216142:LT40_RS18400
uniprot id: A0A089YXY4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

216142:LT40 RS05205
gene id: 216142:LT40_RS05205
uniprot id: A0A089YT36
names: Similarity
messages: Belongs to the UPF0270 family.

216142:LT40 RS02475
gene id: 216142:LT40_RS02475
uniprot id: A0A089YL72
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliQ/MopD/SpaQ family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

216142:LT40 RS14000
gene id: 216142:LT40_RS14000
uniprot id: A0A089YVS0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ThiC family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
messages: Homodimer.

216142:LT40 RS20690
gene id: 216142:LT40_RS20690
uniprot id: A0A089YZ20
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the malate synthase family. GlcB subfamily.
messages: Cytoplasm
messages: Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

216142:LT40 RS15390
gene id: 216142:LT40_RS15390
uniprot id: A0A089YQJ0
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

216142:LT40 RS01120
gene id: 216142:LT40_RS01120
uniprot id: A0A089YQW1
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.
messages: Forms an icosahedral capsid composed of 60 subunits, arranged as a dodecamer of pentamers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

216142:LT40 RS07690
gene id: 216142:LT40_RS07690
uniprot id: A0A089YSE6
names: Subcellular Location Annotation
messages: Membrane

216142:LT40 RS07935
gene id: 216142:LT40_RS07935
uniprot id: A0A089YUH1
names: Subcellular Location Annotation
messages: Membrane

216142:LT40 RS16095
gene id: 216142:LT40_RS16095
uniprot id: A0A089YWY8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase A chain family.
messages: Cell membrane
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

216142:LT40 RS08140
gene id: 216142:LT40_RS08140
uniprot id: A0A089YSQ4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

216142:LT40 RS13755
gene id: 216142:LT40_RS13755
uniprot id: A0A089YVN5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.
messages: Belongs to the RNR ribonuclease family. RNase R subfamily.
messages: Cytoplasm

216142:LT40 RS17640
gene id: 216142:LT40_RS17640
uniprot id: A0A089Z091
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Catalyzes the sodium-dependent uptake of extracellular L-proline.
messages: Cell inner membrane
messages: Membrane

216142:LT40 RS11030
gene id: 216142:LT40_RS11030
uniprot id: A0A089YNF2
names: Similarity
messages: Belongs to the 6-phosphogluconate dehydrogenase family.

216142:LT40 RS17290
gene id: 216142:LT40_RS17290
uniprot id: A0A089YXH0
names: Similarity
messages: Belongs to the outer membrane porin (Opr) (TC 1.B.25) family.

216142:LT40 RS01740
gene id: 216142:LT40_RS01740
uniprot id: A0A089ZPN5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SbcD family.
messages: Heterodimer of SbcC and SbcD.
messages: SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity.

216142:LT40 RS18335
gene id: 216142:LT40_RS18335
uniprot id: A0A089YUK5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

216142:LT40 RS09850
gene id: 216142:LT40_RS09850
uniprot id: A0A089YMR1
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

216142:LT40 RS18370
gene id: 216142:LT40_RS18370
uniprot id: A0A089ZRF7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

216142:LT40 RS01325
gene id: 216142:LT40_RS01325
uniprot id: A0A089YP36
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

216142:LT40 RS11715
gene id: 216142:LT40_RS11715
uniprot id: A0A089YWD0
names: Subcellular Location Annotation
messages: Membrane

216142:LT40 RS05940
gene id: 216142:LT40_RS05940
uniprot id: A0A089YTF6
names: Subcellular Location Annotation
messages: Cell inner membrane

216142:LT40 RS14645
gene id: 216142:LT40_RS14645
uniprot id: A0A089ZR18
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ThiG family.
messages: Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
messages: Cytoplasm
messages: Homotetramer. Forms heterodimers with either ThiH or ThiS.

216142:LT40 RS14020
gene id: 216142:LT40_RS14020
uniprot id: A0A089ZQZ4
names: Similarity
messages: Belongs to the ModE family.

216142:LT40 RS00110
gene id: 216142:LT40_RS00110
uniprot id: A0A089YNL2
names: Similarity
messages: Belongs to the bacterial PQQ dehydrogenase family.

216142:LT40 RS03545
gene id: 216142:LT40_RS03545
uniprot id: A0A089YQ77
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

216142:LT40 RS13445
gene id: 216142:LT40_RS13445
uniprot id: A0A089YXD1
names: Function
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

216142:LT40 RS04955
gene id: 216142:LT40_RS04955
uniprot id: A0A089YQZ6
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvB family.
messages: Cytoplasm
messages: Has 3 domains, the large (RuvB-L) and small ATPase (RuvB-S) domains and the C-terminal head (RuvB-H) domain. The head domain binds DNA, while the ATPase domains jointly bind ATP, ADP or are empty depending on the state of the subunit in the translocation cycle. During a single DNA translocation step the structure of each domain remains the same, but their relative positions change.
messages: Homohexamer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time. Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange. Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration. The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration. Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.

216142:LT40 RS11395
gene id: 216142:LT40_RS11395
uniprot id: A0A089YQX0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 6 family.
messages: Cell membrane
messages: Composed of 13 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

216142:LT40 RS06885
gene id: 216142:LT40_RS06885
uniprot id: A0A089YRX1
names: Similarity
messages: Belongs to the HMG-CoA lyase family.

216142:LT40 RS10795
gene id: 216142:LT40_RS10795
uniprot id: A0A089ZQM4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dsrC/tusE family.
messages: Cytoplasm
messages: Part of a sulfur-relay system.

216142:LT40 RS00475
gene id: 216142:LT40_RS00475
uniprot id: A0A089YK70
names: Function
names: Similarity
messages: Belongs to the LpxB family.
messages: Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

216142:LT40 RS10850
gene id: 216142:LT40_RS10850
uniprot id: A0A089ZQM6
names: Similarity
messages: Belongs to the type IB topoisomerase family.

216142:LT40 RS08990
gene id: 216142:LT40_RS08990
uniprot id: A0A089YPM9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ZipA family.
messages: Cell inner membrane
messages: Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins.
messages: Interacts with FtsZ via their C-terminal domains.

216142:LT40 RS14595
gene id: 216142:LT40_RS14595
uniprot id: A0A089YW08
names: Similarity
messages: Belongs to the GSP E family.

216142:LT40 RS03760
gene id: 216142:LT40_RS03760
uniprot id: A0A089YSA4
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

216142:LT40 RS19850
gene id: 216142:LT40_RS19850
uniprot id: A0A089YVD1
names: Function
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.
messages: Provides the (R)-glutamate required for cell wall biosynthesis.

216142:LT40 RS12650
gene id: 216142:LT40_RS12650
uniprot id: A0A089YP57
names: Similarity
messages: Belongs to the ETF beta-subunit/FixA family.

216142:LT40 RS14865
gene id: 216142:LT40_RS14865
uniprot id: A0A089YQB1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0073 (Hly-III) family.
messages: Membrane

216142:LT40 RS13800
gene id: 216142:LT40_RS13800
uniprot id: A0A089YS66
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the band 7/mec-2 family. HflK subfamily.
messages: HflC and HflK could encode or regulate a protease.
messages: HflC and HflK may interact to form a multimeric complex.
messages: Membrane

216142:LT40 RS10660
gene id: 216142:LT40_RS10660
uniprot id: A0A089YN73
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

216142:LT40 RS00645
gene id: 216142:LT40_RS00645
uniprot id: A0A089YHY7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HAK/KUP transporter (TC 2.A.72) family.
messages: Cell membrane
messages: Membrane
messages: Transport of potassium into the cell. Likely operates as a K(+):H(+) symporter.

216142:LT40 RS01030
gene id: 216142:LT40_RS01030
uniprot id: A0A089YNY7
names: Subcellular Location Annotation
messages: Membrane

216142:LT40 RS04285
gene id: 216142:LT40_RS04285
uniprot id: A0A089YJW0
names: Cofactor
messages: Binds 2 Mg(2+) ions per monomer.

216142:LT40 RS19640
gene id: 216142:LT40_RS19640
uniprot id: A0A089YVA0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LemA family.
messages: Membrane

216142:LT40 RS08475
gene id: 216142:LT40_RS08475
uniprot id: A0A089YSV7
names: Subcellular Location Annotation
messages: Membrane

216142:LT40 RS15835
gene id: 216142:LT40_RS15835
uniprot id: A0A089YZ99
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

216142:LT40 RS14010
gene id: 216142:LT40_RS14010
uniprot id: A0A089YS97
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

216142:LT40 RS11875
gene id: 216142:LT40_RS11875
uniprot id: A0A089YNR9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

216142:LT40 RS06795
gene id: 216142:LT40_RS06795
uniprot id: A0A089YNI4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Cell inner membrane
messages: Membrane

216142:LT40 RS06375
gene id: 216142:LT40_RS06375
uniprot id: A0A089ZQ60
names: Similarity
messages: Belongs to the UDP-galactopyranose/dTDP-fucopyranose mutase family.

216142:LT40 RS00355
gene id: 216142:LT40_RS00355
uniprot id: A0A089ZPI4
names: Similarity
messages: Belongs to the SufE family.

216142:LT40 RS04835
gene id: 216142:LT40_RS04835
uniprot id: A0A089YMI0
names: Subcellular Location Annotation
messages: Membrane

216142:LT40 RS17685
gene id: 216142:LT40_RS17685
uniprot id: A0A089YU81
names: Function
names: Similarity
messages: Belongs to the protein kinase superfamily. KdkA/rfaP family.
messages: Catalyzes the phosphorylation of heptose(I) of the outer membrane lipopolysaccharide core.

216142:LT40 RS04650
gene id: 216142:LT40_RS04650
uniprot id: A0A089YME4
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

216142:LT40 RS01290
gene id: 216142:LT40_RS01290
uniprot id: A0A089ZPL9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Reduced FMN (FMNH(2)).

216142:LT40 RS12890
gene id: 216142:LT40_RS12890
uniprot id: A0A089ZQV2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

216142:LT40 RS18015
gene id: 216142:LT40_RS18015
uniprot id: A0A089ZRE5
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

216142:LT40 RS16425
gene id: 216142:LT40_RS16425
uniprot id: A0A089YX41
names: Similarity
names: Subunit
messages: Belongs to the bacterial histone-like protein family.
messages: Heterodimer of an alpha and a beta chain.

216142:LT40 RS01085
gene id: 216142:LT40_RS01085
uniprot id: A0A089YI60
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: May also have succinyldiaminopimelate aminotransferase activity, thus carrying out the corresponding step in lysine biosynthesis.

216142:LT40 RS13690
gene id: 216142:LT40_RS13690
uniprot id: A0A089YS50
names: Function
names: PTM
names: Similarity
messages: Belongs to the NAPRTase family.
messages: Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP.
messages: Transiently phosphorylated on a His residue during the reaction cycle. Phosphorylation strongly increases the affinity for substrates and increases the rate of nicotinate D-ribonucleotide production. Dephosphorylation regenerates the low-affinity form of the enzyme, leading to product release.

216142:LT40 RS15605
gene id: 216142:LT40_RS15605
uniprot id: A0A089YZ48
names: Subcellular Location Annotation
messages: Membrane

216142:LT40 RS19325
gene id: 216142:LT40_RS19325
uniprot id: A0A089YV57
names: Function
names: Subunit
messages: Binds the second messenger bis-(3'-5') cyclic dimeric guanosine monophosphate (c-di-GMP). Can bind two c-di-GMP molecules per monomer. May play a role in bacterial second-messenger regulated processes. Binding to c-di-GMP induces a conformational change of the C- and N-termini resulting in the exposure of a highly negative surface on one side of the protein to a possible effector protein.
messages: Monomer in both c-di-GMP-bound and free forms.

216142:LT40 RS20345
gene id: 216142:LT40_RS20345
uniprot id: A0A089YYW9
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

216142:LT40 RS11405
gene id: 216142:LT40_RS11405
uniprot id: A0A089ZQP7
names: Subcellular Location Annotation
messages: Membrane

216142:LT40 RS09680
gene id: 216142:LT40_RS09680
uniprot id: A0A089YMN2
names: Subcellular Location Annotation
messages: Membrane

216142:LT40 RS02415
gene id: 216142:LT40_RS02415
uniprot id: A0A089YPM5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliH family.
messages: Cytoplasm
messages: Needed for flagellar regrowth and assembly.

216142:LT40 RS12360
gene id: 216142:LT40_RS12360
uniprot id: A0A089YRB5
names: Subcellular Location Annotation
messages: Membrane

216142:LT40 RS05935
gene id: 216142:LT40_RS05935
uniprot id: A0A089YN57
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thioester dehydratase family. FabA subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)-decenoyl-ACP. Can catalyze the dehydratase reaction for beta-hydroxyacyl-ACPs with saturated chain lengths up to 16:0, being most active on intermediate chain length.

216142:LT40 RS16225
gene id: 216142:LT40_RS16225
uniprot id: A0A089YX07
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the pyridoxine kinase family. PdxY subfamily.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP.

216142:LT40 RS20455
gene id: 216142:LT40_RS20455
uniprot id: A0A089YYY4
names: Function
messages: Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors. CheA is autophosphorylated; it can transfer its phosphate group to either CheB or CheY.

216142:LT40 RS12450
gene id: 216142:LT40_RS12450
uniprot id: A0A089YWR2
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

216142:LT40 RS03135
gene id: 216142:LT40_RS03135
uniprot id: A0A089YJB1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M17 family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm
messages: Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.

216142:LT40 RS05780
gene id: 216142:LT40_RS05780
uniprot id: A0A089YN35
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CpxP/Spy family.
messages: Periplasm

216142:LT40 RS00610
gene id: 216142:LT40_RS00610
uniprot id: A0A089ZPJ4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial diacylglycerol kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of sn-l,2-diacylglycerol (DAG) to phosphatidic acid. Involved in the recycling of diacylglycerol produced as a by-product during membrane-derived oligosaccharide (MDO) biosynthesis.
messages: Cell inner membrane
messages: Membrane
messages: Mn(2+), Zn(2+), Cd(2+) and Co(2+) support activity to lesser extents.

216142:LT40 RS16045
gene id: 216142:LT40_RS16045
uniprot id: A0A089YWV4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

216142:LT40 RS14115
gene id: 216142:LT40_RS14115
uniprot id: A0A089YSB5
names: Subcellular Location Annotation
messages: Membrane

216142:LT40 RS16725
gene id: 216142:LT40_RS16725
uniprot id: A0A089YX88
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.

216142:LT40 RS04035
gene id: 216142:LT40_RS04035
uniprot id: A0A089YJR5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

216142:LT40 RS14050
gene id: 216142:LT40_RS14050
uniprot id: A0A089YVS7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dethiobiotin synthetase family.
messages: Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

216142:LT40 RS01000
gene id: 216142:LT40_RS01000
uniprot id: A0A089YKE8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the trans-sulfuration enzymes family. MetZ subfamily.
messages: Catalyzes the formation of L-homocysteine from O-succinyl-L-homoserine (OSHS) and hydrogen sulfide.
messages: Homotetramer.

216142:LT40 RS13695
gene id: 216142:LT40_RS13695
uniprot id: A0A089YY71
names: Function
names: Subcellular Location Annotation
messages: Periplasm
messages: Transfers electrons from cytochrome c551 to cytochrome oxidase.

216142:LT40 RS15125
gene id: 216142:LT40_RS15125
uniprot id: A0A089ZR35
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

216142:LT40 RS15930
gene id: 216142:LT40_RS15930
uniprot id: A0A089YT78
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the shikimate dehydrogenase family.
messages: Homodimer.
messages: Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

216142:LT40 RS19045
gene id: 216142:LT40_RS19045
uniprot id: A0A089Z116
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

216142:LT40 RS00615
gene id: 216142:LT40_RS00615
uniprot id: A0A089YNS8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

216142:LT40 RS03530
gene id: 216142:LT40_RS03530
uniprot id: A0A089YLU0
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity.

216142:LT40 RS11045
gene id: 216142:LT40_RS11045
uniprot id: A0A089ZQN3
names: Similarity
messages: Belongs to the disproportionating enzyme family.

216142:LT40 RS12560
gene id: 216142:LT40_RS12560
uniprot id: A0A089YWT1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

216142:LT40 RS02860
gene id: 216142:LT40_RS02860
uniprot id: A0A089YLI8
names: Subcellular Location Annotation
messages: Membrane

216142:LT40 RS08425
gene id: 216142:LT40_RS08425
uniprot id: A0A089YM29
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the etk/wzc family.
messages: Cell inner membrane
messages: Membrane

216142:LT40 RS16575
gene id: 216142:LT40_RS16575
uniprot id: A0A089YX64
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

216142:LT40 RS20265
gene id: 216142:LT40_RS20265
uniprot id: A0A089YT86
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transglycosylase Slt family.
messages: Cell outer membrane
messages: In the C-terminal section; belongs to the transglycosylase Slt family.
messages: In the N-terminal section; belongs to the bacterial solute-binding protein 3 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella.
messages: The N-terminal domain does not have lytic activity and probably modulates enzymatic activity. The C-terminal domain is the catalytic active domain.

216142:LT40 RS11365
gene id: 216142:LT40_RS11365
uniprot id: A0A089YNJ2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Cell membrane
messages: In the C-terminal section; belongs to the complex I 49 kDa subunit family.
messages: In the N-terminal section; belongs to the complex I 30 kDa subunit family.
messages: NDH-1 is composed of 13 different subunits. Subunits NuoB, CD, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

216142:LT40 RS15705
gene id: 216142:LT40_RS15705
uniprot id: A0A089YZ71
names: Similarity
messages: Belongs to the pseudomonas-type ThrB family.

216142:LT40 RS09920
gene id: 216142:LT40_RS09920
uniprot id: A0A089ZQJ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

216142:LT40 RS10710
gene id: 216142:LT40_RS10710
uniprot id: A0A089ZQM1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane-bound acyltransferase family.
messages: Cell inner membrane
messages: Membrane

216142:LT40 RS18330
gene id: 216142:LT40_RS18330
uniprot id: A0A089YS74
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

216142:LT40 RS03525
gene id: 216142:LT40_RS03525
uniprot id: A0A089YJH2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

216142:LT40 RS09215
gene id: 216142:LT40_RS09215
uniprot id: A0A089YPR0
names: Subcellular Location Annotation
messages: Membrane

216142:LT40 RS04045
gene id: 216142:LT40_RS04045
uniprot id: A0A089YSF6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

216142:LT40 RS19120
gene id: 216142:LT40_RS19120
uniprot id: A0A089Z130
names: Similarity
messages: Belongs to the DEAD box helicase family.

216142:LT40 RS14280
gene id: 216142:LT40_RS14280
uniprot id: A0A089ZR04
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: Allosterically activated by HslU binding.
messages: Belongs to the peptidase T1B family. HslV subfamily.
messages: Cytoplasm
messages: Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.

216142:LT40 RS16115
gene id: 216142:LT40_RS16115
uniprot id: A0A089ZR72
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family. T3SS ATPase subfamily.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has four main subunits: a(1), b(1), b'(1) and c(9-12).
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

216142:LT40 RS14260
gene id: 216142:LT40_RS14260
uniprot id: A0A089YVV9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

216142:LT40 RS13160
gene id: 216142:LT40_RS13160
uniprot id: A0A089YPG1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

216142:LT40 RS20005
gene id: 216142:LT40_RS20005
uniprot id: A0A089Z1I2
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

216142:LT40 RS07280
gene id: 216142:LT40_RS07280
uniprot id: A0A089YNQ8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. Thiolase family.
messages: Catalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed.
messages: Cytoplasm
messages: Heterotetramer of two alpha chains (FadB) and two beta chains (FadA).

216142:LT40 RS11890
gene id: 216142:LT40_RS11890
uniprot id: A0A089ZQR5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MgtC/SapB family.
messages: Cell inner membrane
messages: Membrane

216142:LT40 RS01810
gene id: 216142:LT40_RS01810
uniprot id: A0A089YKS6
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family. GreB subfamily.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length.

216142:LT40 RS14790
gene id: 216142:LT40_RS14790
uniprot id: A0A089YQA1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell membrane

216142:LT40 RS16110
gene id: 216142:LT40_RS16110
uniprot id: A0A089YZG8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase delta chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

216142:LT40 RS00400
gene id: 216142:LT40_RS00400
uniprot id: A0A089YK58
names: Activity Regulation
names: Caution
names: Domain
names: Function
names: Similarity
messages: Belongs to the GlnD family.
messages: Has four distinct domains: an N-terminal nucleotidyltransferase (NT) domain responsible for UTase activity, a central HD domain that encodes UR activity, and two C-terminal ACT domains that seem to have a role in glutamine sensing.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen metabolism.
messages: Uridylyltransferase (UTase) activity is inhibited by glutamine, while glutamine activates uridylyl-removing (UR) activity.

216142:LT40 RS03800
gene id: 216142:LT40_RS03800
uniprot id: A0A089YJM4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptA family.
messages: Component of the lipopolysaccharide transport and assembly complex.
messages: Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm.
messages: Periplasm

216142:LT40 RS07520
gene id: 216142:LT40_RS07520
uniprot id: A0A089ZQA3
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

216142:LT40 RS01660
gene id: 216142:LT40_RS01660
uniprot id: A0A089ZPN2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

216142:LT40 RS18170
gene id: 216142:LT40_RS18170
uniprot id: A0A089ZRF1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

216142:LT40 RS09135
gene id: 216142:LT40_RS09135
uniprot id: A0A089YV10
names: Subcellular Location Annotation
messages: Periplasm

216142:LT40 RS11255
gene id: 216142:LT40_RS11255
uniprot id: A0A089YUB6
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

216142:LT40 RS00310
gene id: 216142:LT40_RS00310
uniprot id: A0A089YNN5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase D family.
messages: Cytoplasm
messages: Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides.

216142:LT40 RS18710
gene id: 216142:LT40_RS18710
uniprot id: A0A089YUT7
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

216142:LT40 RS07360
gene id: 216142:LT40_RS07360
uniprot id: A0A089YU52
names: Similarity
messages: Belongs to the CmpA/NrtA family.

216142:LT40 RS18845
gene id: 216142:LT40_RS18845
uniprot id: A0A089ZRH5
names: Similarity
messages: Belongs to the peptidase S66 family.

216142:LT40 RS18225
gene id: 216142:LT40_RS18225
uniprot id: A0A089YXV9
names: Function
names: Similarity
messages: Belongs to the anhydro-N-acetylmuramic acid kinase family.
messages: Catalyzes the specific phosphorylation of 1,6-anhydro-N-acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling.

216142:LT40 RS03715
gene id: 216142:LT40_RS03715
uniprot id: A0A089ZPW0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YhdE subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

216142:LT40 RS04885
gene id: 216142:LT40_RS04885
uniprot id: A0A089YK91
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

216142:LT40 RS05380
gene id: 216142:LT40_RS05380
uniprot id: A0A089ZRQ0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

216142:LT40 RS19835
gene id: 216142:LT40_RS19835
uniprot id: A0A089ZRL2
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

216142:LT40 RS10735
gene id: 216142:LT40_RS10735
uniprot id: A0A089YVZ7
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

216142:LT40 RS17945
gene id: 216142:LT40_RS17945
uniprot id: A0A089YUD3
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.

216142:LT40 RS00405
gene id: 216142:LT40_RS00405
uniprot id: A0A089YQJ3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

216142:LT40 RS12970
gene id: 216142:LT40_RS12970
uniprot id: A0A089YX10
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

216142:LT40 RS19475
gene id: 216142:LT40_RS19475
uniprot id: A0A089YSW1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP H family.
messages: Cell inner membrane
messages: Membrane

216142:LT40 RS19965
gene id: 216142:LT40_RS19965
uniprot id: A0A089YYR3
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GDT1 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

216142:LT40 RS04245
gene id: 216142:LT40_RS04245
uniprot id: A0A089YSJ1
names: Subcellular Location Annotation
messages: Membrane

216142:LT40 RS09035
gene id: 216142:LT40_RS09035
uniprot id: A0A089YT50
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

216142:LT40 RS05520
gene id: 216142:LT40_RS05520
uniprot id: A0A089YMZ7
names: Similarity
messages: Belongs to the DEAD box helicase family.

216142:LT40 RS02280
gene id: 216142:LT40_RS02280
uniprot id: A0A089ZPQ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FlgA family.
messages: Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly.
messages: Periplasm

216142:LT40 RS05220
gene id: 216142:LT40_RS05220
uniprot id: A0A089YKG0
names: Similarity
messages: Belongs to the asparagine synthetase family.

216142:LT40 RS03325
gene id: 216142:LT40_RS03325
uniprot id: A0A089YS23
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Cytochrome bo(3) ubiquinol terminal oxidase is the component of the aerobic respiratory chain of E.coli that predominates when cells are grown at high aeration. Has proton pump activity across the membrane in addition to electron transfer, pumping 2 protons/electron.
messages: Heterooctamer of two A chains, two B chains, two C chains and two D chains.
messages: Membrane

216142:LT40 RS19390
gene id: 216142:LT40_RS19390
uniprot id: A0A089YYH1
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

216142:LT40 RS16960
gene id: 216142:LT40_RS16960
uniprot id: A0A089YRH9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

216142:LT40 RS16390
gene id: 216142:LT40_RS16390
uniprot id: A0A089YZK4
names: Subcellular Location Annotation
messages: Membrane

216142:LT40 RS19170
gene id: 216142:LT40_RS19170
uniprot id: A0A089Z137
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

216142:LT40 RS04545
gene id: 216142:LT40_RS04545
uniprot id: A0A089YK10
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
messages: Cytoplasm
messages: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.

216142:LT40 RS18515
gene id: 216142:LT40_RS18515
uniprot id: A0A089Z0Q9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Binds 1 Mg(2+) ion per monomer.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

216142:LT40 RS03360
gene id: 216142:LT40_RS03360
uniprot id: A0A089YQ54
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

216142:LT40 RS06815
gene id: 216142:LT40_RS06815
uniprot id: A0A089YL67
names: Similarity
messages: Belongs to the bacterial solute-binding protein 9 family.

216142:LT40 RS14480
gene id: 216142:LT40_RS14480
uniprot id: A0A089YYL0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecB family.
messages: Cytoplasm
messages: Homotetramer, a dimer of dimers. One homotetramer interacts with 1 SecA dimer.
messages: One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA.

216142:LT40 RS04645
gene id: 216142:LT40_RS04645
uniprot id: A0A089YK36
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer.

216142:LT40 RS12670
gene id: 216142:LT40_RS12670
uniprot id: A0A089YV00
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

216142:LT40 RS14325
gene id: 216142:LT40_RS14325
uniprot id: A0A089YYI1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

216142:LT40 RS11060
gene id: 216142:LT40_RS11060
uniprot id: A0A089YQR8
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

216142:LT40 RS02480
gene id: 216142:LT40_RS02480
uniprot id: A0A089YRL0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliR/MopE/SpaR family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

216142:LT40 RS11035
gene id: 216142:LT40_RS11035
uniprot id: A0A089YQR4
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.
messages: Synthesizes alpha-1,4-glucan chains using ADP-glucose.

216142:LT40 RS12570
gene id: 216142:LT40_RS12570
uniprot id: A0A089YUX3
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: The active site is a redox-active disulfide bond.

216142:LT40 RS16935
gene id: 216142:LT40_RS16935
uniprot id: A0A089YRH6
names: Similarity
messages: Belongs to the UbiH/COQ6 family.

216142:LT40 RS06075
gene id: 216142:LT40_RS06075
uniprot id: A0A089YRK6
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.
messages: There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors.

216142:LT40 RS19145
gene id: 216142:LT40_RS19145
uniprot id: A0A089Z135
names: Similarity
messages: Belongs to the D-glutamate cyclase family.

216142:LT40 RS10390
gene id: 216142:LT40_RS10390
uniprot id: A0A089YN19
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

216142:LT40 RS04985
gene id: 216142:LT40_RS04985
uniprot id: A0A089YKB5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Pal lipoprotein family.
messages: Cell outer membrane
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

216142:LT40 RS12050
gene id: 216142:LT40_RS12050
uniprot id: A0A089YWI8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 1 subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

216142:LT40 RS19295
gene id: 216142:LT40_RS19295
uniprot id: A0A089YV53
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RlmG family.
messages: Cytoplasm
messages: Specifically methylates the guanine in position 1835 (m2G1835) of 23S rRNA.

216142:LT40 RS04385
gene id: 216142:LT40_RS04385
uniprot id: A0A089YQL5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
messages: Cell inner membrane
messages: Membrane

216142:LT40 RS08900
gene id: 216142:LT40_RS08900
uniprot id: A0A089YT27
names: Function
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic Ku family.
messages: Homodimer. Interacts with LigD.
messages: With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD.

216142:LT40 RS16950
gene id: 216142:LT40_RS16950
uniprot id: A0A089ZRA5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

216142:LT40 RS11010
gene id: 216142:LT40_RS11010
uniprot id: A0A089YQR1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Nudix hydrolase family. NudC subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Divalent metal cations. Mg(2+) or Mn(2+).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: mRNA decapping enzyme that specifically removes the nicotinamide adenine dinucleotide (NAD) cap from a subset of mRNAs by hydrolyzing the diphosphate linkage to produce nicotinamide mononucleotide (NMN) and 5' monophosphate mRNA. The NAD-cap is present at the 5'-end of some mRNAs and stabilizes RNA against 5'-processing. Has preference for mRNAs with a 5'-end purine. Catalyzes the hydrolysis of a broad range of dinucleotide pyrophosphates.

216142:LT40 RS02340
gene id: 216142:LT40_RS02340
uniprot id: A0A089YPL0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Flagellum-specific muramidase which hydrolyzes the peptidoglycan layer to assemble the rod structure in the periplasmic space.
messages: In the C-terminal section; belongs to the glycosyl hydrolase 73 family.
messages: In the N-terminal section; belongs to the FlgJ family.
messages: Periplasm

216142:LT40 RS16300
gene id: 216142:LT40_RS16300
uniprot id: A0A089YX20
names: Similarity
messages: Belongs to the asparaginase 1 family.

216142:LT40 RS02845
gene id: 216142:LT40_RS02845
uniprot id: A0A089ZPS7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit F family.
messages: Cell membrane
messages: Membrane

216142:LT40 RS01925
gene id: 216142:LT40_RS01925
uniprot id: A0A089YPD3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Cell inner membrane
messages: Homoheptamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mechanosensitive channel that participates in the regulation of osmotic pressure changes within the cell, opening in response to stretch forces in the membrane lipid bilayer, without the need for other proteins. Contributes to normal resistance to hypoosmotic shock. Forms an ion channel of 1.0 nanosiemens conductance with a slight preference for anions.

216142:LT40 RS13495
gene id: 216142:LT40_RS13495
uniprot id: A0A089YY41
names: Function
names: Similarity
names: Subunit
messages: Belongs to the precorrin methyltransferase family.
messages: Homodimer.
messages: Methylates precorrin-2 at the C-20 position to produce precorrin-3A.

216142:LT40 RS09955
gene id: 216142:LT40_RS09955
uniprot id: A0A089YMT3
names: Subcellular Location Annotation
messages: Membrane

216142:LT40 RS03020
gene id: 216142:LT40_RS03020
uniprot id: A0A089YRX9
names: Similarity
messages: Belongs to the PhoH family.

216142:LT40 RS14775
gene id: 216142:LT40_RS14775
uniprot id: A0A089YYQ8
names: Similarity
messages: Belongs to the HipA Ser/Thr kinase family.

216142:LT40 RS04105
gene id: 216142:LT40_RS04105
uniprot id: A0A089YQF9
names: Similarity
messages: Belongs to the Nudix hydrolase family.

216142:LT40 RS18055
gene id: 216142:LT40_RS18055
uniprot id: A0A089YUF5
names: Similarity
messages: Belongs to the UPF0229 family.

216142:LT40 RS11000
gene id: 216142:LT40_RS11000
uniprot id: A0A089YU75
names: Similarity
names: Subunit
messages: Belongs to the transketolase family.
messages: Homodimer.

216142:LT40 RS17920
gene id: 216142:LT40_RS17920
uniprot id: A0A089Z0D6
names: Similarity
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.

216142:LT40 RS05330
gene id: 216142:LT40_RS05330
uniprot id: A0A089YT70
names: Similarity
messages: Belongs to the glutaredoxin family. Monothiol subfamily.

216142:LT40 RS12270
gene id: 216142:LT40_RS12270
uniprot id: A0A089ZQS9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Membrane

216142:LT40 RS10680
gene id: 216142:LT40_RS10680
uniprot id: A0A089YU12
names: Similarity
messages: Belongs to the MbcT/ParT/Res family.

216142:LT40 RS13005
gene id: 216142:LT40_RS13005
uniprot id: A0A089YV78
names: Similarity
messages: Belongs to the ribosome association toxin RatA family.

216142:LT40 RS13185
gene id: 216142:LT40_RS13185
uniprot id: A0A089YPG5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

216142:LT40 RS10745
gene id: 216142:LT40_RS10745
uniprot id: A0A089YU39
names: Subcellular Location Annotation
messages: Membrane

216142:LT40 RS09835
gene id: 216142:LT40_RS09835
uniprot id: A0A089YVD7
names: Similarity
messages: Belongs to the gluconokinase GntK/GntV family.

216142:LT40 RS02170
gene id: 216142:LT40_RS02170
uniprot id: A0A089YPI1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase H family.
messages: Binds 1 Mg(2+) ion per subunit. May bind a second metal ion at a regulatory site, or after substrate binding.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Monomer.

216142:LT40 RS03470
gene id: 216142:LT40_RS03470
uniprot id: A0A089YQ68
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

216142:LT40 RS04775
gene id: 216142:LT40_RS04775
uniprot id: A0A089YQV8
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SprT family.
messages: Binds 1 zinc ion.
messages: Cytoplasm

216142:LT40 RS17150
gene id: 216142:LT40_RS17150
uniprot id: A0A089YZZ9
names: Similarity
messages: Belongs to the peptidase M20A family. ArgE subfamily.

216142:LT40 RS00490
gene id: 216142:LT40_RS00490
uniprot id: A0A089YNR0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccA family.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

216142:LT40 RS17160
gene id: 216142:LT40_RS17160
uniprot id: A0A089YXF1
names: Similarity
messages: Belongs to the glutamate--cysteine ligase type 1 family. Type 1 subfamily.

216142:LT40 RS14840
gene id: 216142:LT40_RS14840
uniprot id: A0A089YQA6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0312 family. Type 1 subfamily.
messages: Periplasm

216142:LT40 RS15900
gene id: 216142:LT40_RS15900
uniprot id: A0A089YQV5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

216142:LT40 RS02815
gene id: 216142:LT40_RS02815
uniprot id: A0A089YRV8
names: Similarity
messages: Belongs to the UPF0502 family.

216142:LT40 RS20370
gene id: 216142:LT40_RS20370
uniprot id: A0A089YYX1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbC subfamily.
messages: Periplasm
messages: Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process.

216142:LT40 RS14605
gene id: 216142:LT40_RS14605
uniprot id: A0A089YQ70
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

216142:LT40 RS04330
gene id: 216142:LT40_RS04330
uniprot id: A0A089ZPY4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Aromatic acid:H(+) symporter (AAHS) (TC 2.A.1.15) family.
messages: Membrane

216142:LT40 RS20570
gene id: 216142:LT40_RS20570
uniprot id: A0A089YVR7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

216142:LT40 RS04085
gene id: 216142:LT40_RS04085
uniprot id: A0A089YJS5
names: Function
names: Similarity
messages: Belongs to the LpxC family.
messages: Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.

216142:LT40 RS13455
gene id: 216142:LT40_RS13455
uniprot id: A0A089YVJ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. PrmA family.
messages: Cytoplasm
messages: Methylates ribosomal protein L11.

216142:LT40 RS05765
gene id: 216142:LT40_RS05765
uniprot id: A0A089ZQ37
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TrkH potassium transport family.
messages: Cell inner membrane
messages: Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA.
messages: Membrane

216142:LT40 RS09550
gene id: 216142:LT40_RS09550
uniprot id: A0A089YML2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ElaB/YgaM/YqjD family.
messages: Cell inner membrane
messages: Membrane

216142:LT40 RS17360
gene id: 216142:LT40_RS17360
uniprot id: A0A089ZRC1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class II fructose-bisphosphate aldolase family.
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.
messages: Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.
messages: One is catalytic and the other provides a structural contribution.

216142:LT40 RS09330
gene id: 216142:LT40_RS09330
uniprot id: A0A089YV44
names: Similarity
messages: Belongs to the peptidase S49 family.

216142:LT40 RS09520
gene id: 216142:LT40_RS09520
uniprot id: A0A089YTB8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TamA family.
messages: Cell outer membrane
messages: Membrane

216142:LT40 RS12220
gene id: 216142:LT40_RS12220
uniprot id: A0A089ZQS7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

216142:LT40 RS06875
gene id: 216142:LT40_RS06875
uniprot id: A0A089YTW8
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

216142:LT40 RS11830
gene id: 216142:LT40_RS11830
uniprot id: A0A089YWE8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

216142:LT40 RS00695
gene id: 216142:LT40_RS00695
uniprot id: A0A089ZPJ7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

216142:LT40 RS12320
gene id: 216142:LT40_RS12320
uniprot id: A0A089ZQT1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ureidoglycolate lyase family.
messages: Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source.
messages: Homodimer.

216142:LT40 RS13675
gene id: 216142:LT40_RS13675
uniprot id: A0A089ZQY1
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

216142:LT40 RS19540
gene id: 216142:LT40_RS19540
uniprot id: A0A089ZRK2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.

216142:LT40 RS12370
gene id: 216142:LT40_RS12370
uniprot id: A0A089ZQT3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

216142:LT40 RS09945
gene id: 216142:LT40_RS09945
uniprot id: A0A089ZQJ3
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

216142:LT40 RS20040
gene id: 216142:LT40_RS20040
uniprot id: A0A089Z1I6
names: Similarity
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.

216142:LT40 RS09825
gene id: 216142:LT40_RS09825
uniprot id: A0A089YMQ6
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

216142:LT40 RS15360
gene id: 216142:LT40_RS15360
uniprot id: A0A089YWF3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic sulfate-binding protein family.
messages: Periplasm

216142:LT40 RS12550
gene id: 216142:LT40_RS12550
uniprot id: A0A089YP38
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the branched chain amino acid transporter family.
messages: Cell inner membrane
messages: Component of the transport system for branched-chain amino acids.
messages: Membrane

216142:LT40 RS01320
gene id: 216142:LT40_RS01320
uniprot id: A0A089ZPM0
names: Subcellular Location Annotation
messages: Membrane

216142:LT40 RS14555
gene id: 216142:LT40_RS14555
uniprot id: A0A089YSI3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

216142:LT40 RS11325
gene id: 216142:LT40_RS11325
uniprot id: A0A089YW76
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HflD family.
messages: Cell membrane
messages: Cytoplasm

216142:LT40 RS18435
gene id: 216142:LT40_RS18435
uniprot id: A0A089YUM6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

216142:LT40 RS14335
gene id: 216142:LT40_RS14335
uniprot id: A0A089YVX1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell membrane
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

216142:LT40 RS13190
gene id: 216142:LT40_RS13190
uniprot id: A0A089YRS4
names: Function
names: Similarity
names: Subunit
messages: A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD.
messages: Belongs to the RecD family.
messages: Heterotrimer of RecB, RecC and RecD. All subunits contribute to DNA-binding.

216142:LT40 RS17025
gene id: 216142:LT40_RS17025
uniprot id: A0A089YZX6
names: Similarity
messages: Belongs to the glutamine synthetase family.

216142:LT40 RS16330
gene id: 216142:LT40_RS16330
uniprot id: A0A089YR77
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

216142:LT40 RS12820
gene id: 216142:LT40_RS12820
uniprot id: A0A089YV32
names: Function
names: Similarity
messages: Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control.
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

216142:LT40 RS01910
gene id: 216142:LT40_RS01910
uniprot id: A0A089YKU7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class II aldolase/RraA-like family.
messages: Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2-oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions.
messages: Homotrimer.

216142:LT40 RS10050
gene id: 216142:LT40_RS10050
uniprot id: A0A089YVH4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

216142:LT40 RS02125
gene id: 216142:LT40_RS02125
uniprot id: A0A089YIP9
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.

216142:LT40 RS01975
gene id: 216142:LT40_RS01975
uniprot id: A0A089YPE4
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

216142:LT40 RS18795
gene id: 216142:LT40_RS18795
uniprot id: A0A089ZRH3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein uL14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein uL14 (rplN).

216142:LT40 RS01805
gene id: 216142:LT40_RS01805
uniprot id: A0A089YIH9
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

216142:LT40 RS07070
gene id: 216142:LT40_RS07070
uniprot id: A0A089YTZ5
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

216142:LT40 RS17130
gene id: 216142:LT40_RS17130
uniprot id: A0A089ZRB2
names: Similarity
messages: Belongs to the GSP E family.

216142:LT40 RS18775
gene id: 216142:LT40_RS18775
uniprot id: A0A089YY61
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Membrane

216142:LT40 RS02400
gene id: 216142:LT40_RS02400
uniprot id: A0A089YL57
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliE family.

216142:LT40 RS03500
gene id: 216142:LT40_RS03500
uniprot id: A0A089YJG7
names: Similarity
messages: Belongs to the HesB/IscA family.

216142:LT40 RS16035
gene id: 216142:LT40_RS16035
uniprot id: A0A089YZE6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

216142:LT40 RS02300
gene id: 216142:LT40_RS02300
uniprot id: A0A089YRG9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

216142:LT40 RS03885
gene id: 216142:LT40_RS03885
uniprot id: A0A089YSC7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PAPS reductase family. CysD subfamily.
messages: Heterodimer composed of CysD, the smaller subunit, and CysN.
messages: With CysN forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway. APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD.

216142:LT40 RS05930
gene id: 216142:LT40_RS05930
uniprot id: A0A089YKS7
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

216142:LT40 RS14090
gene id: 216142:LT40_RS14090
uniprot id: A0A089YSB1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response.
messages: Belongs to the SrkA/RdoA protein kinase family.
messages: Cytoplasm
messages: Monomer.

216142:LT40 RS03475
gene id: 216142:LT40_RS03475
uniprot id: A0A089YJG3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.
messages: Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA.
messages: Cytoplasm
messages: Homodimer.

216142:LT40 RS02960
gene id: 216142:LT40_RS02960
uniprot id: A0A089YLK1
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

216142:LT40 RS17665
gene id: 216142:LT40_RS17665
uniprot id: A0A089Z096
names: Function
names: Similarity
messages: Belongs to the GlnE family.
messages: Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell.

216142:LT40 RS10785
gene id: 216142:LT40_RS10785
uniprot id: A0A089YQM8
names: Similarity
messages: Belongs to the DsrF/TusC family.

216142:LT40 RS06340
gene id: 216142:LT40_RS06340
uniprot id: A0A089YTM8
names: Similarity
messages: Belongs to the PrpD family.

216142:LT40 RS12485
gene id: 216142:LT40_RS12485
uniprot id: A0A089ZQT7
names: Activity Regulation
names: Caution
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A peripheral cell membrane enzyme that catalyzes the oxidative decarboxylation of pyruvate to form acetate and CO(2). It channels electrons from the cytoplasm to the respiratory chain at the cell membrane via ubiquinone.
messages: Belongs to the TPP enzyme family.
messages: Binds 1 FAD per subunit.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Cell membrane
messages: Has 4 domains; the Pyr domain which binds the pyrimidine moiety of the thiamine pyrophosphate cofactor, the FAD-binding domain, the PP-binding domain which binds the pyrophosphate portion of thiamine pyrophosphate and the C-terminal membrane binding region. The C-terminus is held closely against the rest of the protein and covers the active site; during activation it unfolds from the rest of the protein and forms an amphipathic helix upon membrane binding, exposing the active site.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The C-terminus inhibits activity; it has to move for the enzyme to be active. Activated by lipid-binding, which occurs via the C-terminus.

216142:LT40 RS18290
gene id: 216142:LT40_RS18290
uniprot id: A0A089Z0K4
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

216142:LT40 RS19240
gene id: 216142:LT40_RS19240
uniprot id: A0A089YV45
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. TrmA subfamily.
messages: Dual-specificity methyltransferase that catalyzes the formation of 5-methyluridine at position 54 (m5U54) in all tRNAs, and that of position 341 (m5U341) in tmRNA (transfer-mRNA).

216142:LT40 RS13640
gene id: 216142:LT40_RS13640
uniprot id: A0A089YS43
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UreF family.
messages: Cytoplasm
messages: Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
messages: UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

216142:LT40 RS18465
gene id: 216142:LT40_RS18465
uniprot id: A0A089Z0P7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

216142:LT40 RS18740
gene id: 216142:LT40_RS18740
uniprot id: A0A089Z0W8
names: Function
names: Similarity
messages: Belongs to the MurCDEF family. Mpl subfamily.
messages: Reutilizes the intact tripeptide L-alanyl-gamma-D-glutamyl-meso-diaminopimelate by linking it to UDP-N-acetylmuramate.

216142:LT40 RS16270
gene id: 216142:LT40_RS16270
uniprot id: A0A089ZR78
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

216142:LT40 RS00940
gene id: 216142:LT40_RS00940
uniprot id: A0A089YKE0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Catalyzes the last two steps in the biosynthesis of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the DAO family.
messages: In the N-terminal section; belongs to the methyltransferase superfamily. tRNA (mnm(5)s(2)U34)-methyltransferase family.

216142:LT40 RS06505
gene id: 216142:LT40_RS06505
uniprot id: A0A089YND6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Cell inner membrane
messages: Membrane

216142:LT40 RS01205
gene id: 216142:LT40_RS01205
uniprot id: A0A089YKH2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

216142:LT40 RS09220
gene id: 216142:LT40_RS09220
uniprot id: A0A089YV24
names: Similarity
messages: Belongs to the polysaccharide synthase family.

216142:LT40 RS06215
gene id: 216142:LT40_RS06215
uniprot id: A0A089YKX8
names: Similarity
messages: Belongs to the ACC deaminase/D-cysteine desulfhydrase family.

216142:LT40 RS09075
gene id: 216142:LT40_RS09075
uniprot id: A0A089YUZ9
names: Similarity
messages: Belongs to the ABC transporter superfamily.

216142:LT40 RS06415
gene id: 216142:LT40_RS06415
uniprot id: A0A089YL08
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

216142:LT40 RS03260
gene id: 216142:LT40_RS03260
uniprot id: A0A089YJC8
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

216142:LT40 RS20480
gene id: 216142:LT40_RS20480
uniprot id: A0A089ZRN6
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

216142:LT40 RS10480
gene id: 216142:LT40_RS10480
uniprot id: A0A089YVS6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein SsuA/TauA family.
messages: Periplasm

216142:LT40 RS10655
gene id: 216142:LT40_RS10655
uniprot id: A0A089YTY8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Membrane

216142:LT40 RS02100
gene id: 216142:LT40_RS02100
uniprot id: A0A089YIP3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

216142:LT40 RS14910
gene id: 216142:LT40_RS14910
uniprot id: A0A089YW71
names: Function
names: Similarity
messages: Belongs to the Fe(2+)-trafficking protein family.
messages: Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes.

216142:LT40 RS14160
gene id: 216142:LT40_RS14160
uniprot id: A0A089YPZ8
names: Similarity
messages: Belongs to the GcvT family.

216142:LT40 RS15875
gene id: 216142:LT40_RS15875
uniprot id: A0A089YQV0
names: Similarity
messages: To bacterial alkanal monooxygenase alpha and beta chains.

216142:LT40 RS16865
gene id: 216142:LT40_RS16865
uniprot id: A0A089YTT8
names: Similarity
messages: Belongs to the thioredoxin family.

216142:LT40 RS07495
gene id: 216142:LT40_RS07495
uniprot id: A0A089ZQA2
names: Subcellular Location Annotation
messages: Cytoplasm

216142:LT40 RS05695
gene id: 216142:LT40_RS05695
uniprot id: A0A089YRE6
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

216142:LT40 RS11005
gene id: 216142:LT40_RS11005
uniprot id: A0A089YNE8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

216142:LT40 RS04670
gene id: 216142:LT40_RS04670
uniprot id: A0A089YK42
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

216142:LT40 RS15330
gene id: 216142:LT40_RS15330
uniprot id: A0A089ZR43
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NlpA lipoprotein family.
messages: Membrane

216142:LT40 RS19730
gene id: 216142:LT40_RS19730
uniprot id: A0A089ZRK8
names: Function
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.
messages: Catalyzes the ATP-dependent phosphorylation of fructose-l-phosphate to fructose-l,6-bisphosphate.

216142:LT40 RS12790
gene id: 216142:LT40_RS12790
uniprot id: A0A089ZQU8
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

216142:LT40 RS05200
gene id: 216142:LT40_RS05200
uniprot id: A0A089YMQ8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Mediates global changes in gene expression, shifting from rapid growth to stress survival by linking envelope stress, the stringent response and the catabolite repression systems. Usually binds in the 5'-UTR; binding at or near the Shine-Dalgarno sequence prevents ribosome-binding, repressing translation, binding elsewhere in the 5'-UTR can activate translation and/or stabilize the mRNA. Its function is antagonized by small RNA(s).
messages: Belongs to the CsrA/RsmA family.
messages: Cytoplasm
messages: Homodimer; the beta-strands of each monomer intercalate to form a hydrophobic core, while the alpha-helices form wings that extend away from the core.

216142:LT40 RS00670
gene id: 216142:LT40_RS00670
uniprot id: A0A089YNT4
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

216142:LT40 RS06170
gene id: 216142:LT40_RS06170
uniprot id: A0A089ZQ53
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS1 family.
messages: Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence.

216142:LT40 RS13435
gene id: 216142:LT40_RS13435
uniprot id: A0A089YPP6
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

216142:LT40 RS05195
gene id: 216142:LT40_RS05195
uniprot id: A0A089YKF4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0060 family.
messages: Cell membrane

216142:LT40 RS16410
gene id: 216142:LT40_RS16410
uniprot id: A0A089YTK7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family.
messages: Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate.
messages: Cell inner membrane

216142:LT40 RS02405
gene id: 216142:LT40_RS02405
uniprot id: A0A089YRJ2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the FliF family.
messages: Membrane
messages: The M ring may be actively involved in energy transduction.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The M ring is integral to the inner membrane of the cell and may be connected to the flagellar rod via the S ring. The S (supramembrane ring) lies just distal to the M ring. The L and P rings lie in the outer membrane and the periplasmic space, respectively.

216142:LT40 RS18010
gene id: 216142:LT40_RS18010
uniprot id: A0A089Z0F4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoD/SigA subfamily.
messages: Cytoplasm
messages: Interacts transiently with the RNA polymerase catalytic core.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.

216142:LT40 RS20790
gene id: 216142:LT40_RS20790
uniprot id: A0A089Z1W3
names: Subcellular Location Annotation
messages: Membrane

216142:LT40 RS18500
gene id: 216142:LT40_RS18500
uniprot id: A0A089YY00
names: Subcellular Location Annotation
messages: Membrane

216142:LT40 RS07730
gene id: 216142:LT40_RS07730
uniprot id: A0A089YUC9
names: Similarity
messages: Belongs to the HMG-CoA lyase family.

216142:LT40 RS15245
gene id: 216142:LT40_RS15245
uniprot id: A0A089YYY9
names: Similarity
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.

216142:LT40 RS05945
gene id: 216142:LT40_RS05945
uniprot id: A0A089ZQ44
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

216142:LT40 RS01760
gene id: 216142:LT40_RS01760
uniprot id: A0A089YR56
names: Subcellular Location Annotation
messages: Membrane

216142:LT40 RS15325
gene id: 216142:LT40_RS15325
uniprot id: A0A089YZ03
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
messages: Cell inner membrane
messages: Membrane

216142:LT40 RS18785
gene id: 216142:LT40_RS18785
uniprot id: A0A089YUX7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

216142:LT40 RS11265
gene id: 216142:LT40_RS11265
uniprot id: A0A089YQU8
names: Function
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.
messages: DNA-dependent ATPase that plays important roles in cellular responses to stalled DNA replication processes.

216142:LT40 RS06395
gene id: 216142:LT40_RS06395
uniprot id: A0A089YNC0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

216142:LT40 RS15255
gene id: 216142:LT40_RS15255
uniprot id: A0A089YWC4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm

216142:LT40 RS19025
gene id: 216142:LT40_RS19025
uniprot id: A0A089ZRI2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

216142:LT40 RS01040
gene id: 216142:LT40_RS01040
uniprot id: A0A089YKF2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. YhhS family.
messages: Cell inner membrane
messages: Membrane

216142:LT40 RS15790
gene id: 216142:LT40_RS15790
uniprot id: A0A089YWP8
names: Cofactor
messages: Binds 3 heme c groups covalently per subunit.

216142:LT40 RS17075
gene id: 216142:LT40_RS17075
uniprot id: A0A089YZY6
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

216142:LT40 RS16740
gene id: 216142:LT40_RS16740
uniprot id: A0A089YZS1
names: Function
names: Similarity
messages: Belongs to the frataxin family.
messages: Involved in iron-sulfur (Fe-S) cluster assembly. May act as a regulator of Fe-S biogenesis.

216142:LT40 RS13425
gene id: 216142:LT40_RS13425
uniprot id: A0A089ZQX1
names: Similarity
messages: Belongs to the Nudix hydrolase family.

216142:LT40 RS00680
gene id: 216142:LT40_RS00680
uniprot id: A0A089YHZ2
names: Similarity
messages: Belongs to the peptidase S49 family.

216142:LT40 RS14895
gene id: 216142:LT40_RS14895
uniprot id: A0A089YSN6
names: Subcellular Location Annotation
messages: Membrane

216142:LT40 RS12015
gene id: 216142:LT40_RS12015
uniprot id: A0A089YR57
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

216142:LT40 RS07025
gene id: 216142:LT40_RS07025
uniprot id: A0A089YLA7
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

216142:LT40 RS02700
gene id: 216142:LT40_RS02700
uniprot id: A0A089YJ57
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

216142:LT40 RS15350
gene id: 216142:LT40_RS15350
uniprot id: A0A089YZ08
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Membrane
messages: Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (CysA), two transmembrane proteins (CysT and CysW) and a solute-binding protein (CysP).

216142:LT40 RS04825
gene id: 216142:LT40_RS04825
uniprot id: A0A089YQW8
names: Similarity
messages: Belongs to the MlaA family.

216142:LT40 RS18555
gene id: 216142:LT40_RS18555
uniprot id: A0A089YSD0
names: Similarity
messages: Belongs to the thioredoxin family.

216142:LT40 RS14080
gene id: 216142:LT40_RS14080
uniprot id: A0A089YVT1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein SsuA/TauA family.
messages: Periplasm

216142:LT40 RS03005
gene id: 216142:LT40_RS03005
uniprot id: A0A089YPZ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
messages: Cytoplasm
messages: Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.

216142:LT40 RS14300
gene id: 216142:LT40_RS14300
uniprot id: A0A089YYH6
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2).

216142:LT40 RS03430
gene id: 216142:LT40_RS03430
uniprot id: A0A089YLS6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane

216142:LT40 RS11800
gene id: 216142:LT40_RS11800
uniprot id: A0A089YWE3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

216142:LT40 RS19525
gene id: 216142:LT40_RS19525
uniprot id: A0A089YSW9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamD family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

216142:LT40 RS02865
gene id: 216142:LT40_RS02865
uniprot id: A0A089YRW4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

216142:LT40 RS03910
gene id: 216142:LT40_RS03910
uniprot id: A0A089YSD2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm
messages: Homodimer.

216142:LT40 RS10995
gene id: 216142:LT40_RS10995
uniprot id: A0A089ZQN1
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Homooctamer.

216142:LT40 RS09510
gene id: 216142:LT40_RS09510
uniprot id: A0A089YV81
names: Cofactor
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.
messages: Probably binds two magnesium or manganese ions per subunit.

216142:LT40 RS07740
gene id: 216142:LT40_RS07740
uniprot id: A0A089YSF8
names: Similarity
messages: Belongs to the type III secretion exporter family.

216142:LT40 RS04095
gene id: 216142:LT40_RS04095
uniprot id: A0A089YSG6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

216142:LT40 RS13105
gene id: 216142:LT40_RS13105
uniprot id: A0A089YPE7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

216142:LT40 RS04110
gene id: 216142:LT40_RS04110
uniprot id: A0A089YJT0
names: Similarity
messages: Belongs to the Cob(I)alamin adenosyltransferase family.

216142:LT40 RS14445
gene id: 216142:LT40_RS14445
uniprot id: A0A089YQ44
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glutamine synthetase family.
messages: Cytoplasm
messages: Oligomer of 12 subunits arranged in the form of two hexagons.

216142:LT40 RS14905
gene id: 216142:LT40_RS14905
uniprot id: A0A089ZR28
names: Cofactor
names: Function
names: Similarity
messages: Adenine glycosylase active on G-A mispairs. MutY also corrects error-prone DNA synthesis past GO lesions which are due to the oxidatively damaged form of guanine: 7,8-dihydro-8-oxoguanine (8-oxo-dGTP).
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.

216142:LT40 RS16645
gene id: 216142:LT40_RS16645
uniprot id: A0A089ZR93
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

216142:LT40 RS14175
gene id: 216142:LT40_RS14175
uniprot id: A0A089ZR00
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.

216142:LT40 RS17820
gene id: 216142:LT40_RS17820
uniprot id: A0A089YRX3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

216142:LT40 RS00520
gene id: 216142:LT40_RS00520
uniprot id: A0A089YHW9
names: Function
names: Similarity
messages: Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).

216142:LT40 RS07075
gene id: 216142:LT40_RS07075
uniprot id: A0A089ZQ86
names: Similarity
messages: Belongs to the FAD-dependent oxidoreductase family.

216142:LT40 RS16415
gene id: 216142:LT40_RS16415
uniprot id: A0A089YZK9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiC family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4-hydroxybenzoate (4HB) for the ubiquinone pathway.

216142:LT40 RS11175
gene id: 216142:LT40_RS11175
uniprot id: A0A089ZQN8
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the gamma-glutamyltransferase family.
messages: Cleaved by autocatalysis into a large and a small subunit.
messages: This enzyme consists of two polypeptide chains, which are synthesized in precursor form from a single polypeptide.

216142:LT40 RS04125
gene id: 216142:LT40_RS04125
uniprot id: A0A089ZPX6
names: Similarity
messages: Belongs to the UPF0234 family.

216142:LT40 RS02875
gene id: 216142:LT40_RS02875
uniprot id: A0A089YPY5
names: Similarity
messages: Belongs to the peptidase M24B family.

216142:LT40 RS09785
gene id: 216142:LT40_RS09785
uniprot id: A0A089YVC9
names: Similarity
messages: Belongs to the UPF0337 (CsbD) family.

216142:LT40 RS18230
gene id: 216142:LT40_RS18230
uniprot id: A0A089YS61
names: Subcellular Location Annotation
messages: Membrane

216142:LT40 RS19765
gene id: 216142:LT40_RS19765
uniprot id: A0A089YT06
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the isocitrate lyase family. Oxaloacetate decarboxylase subfamily.
messages: Belongs to the isocitrate lyase/PEP mutase superfamily. Oxaloacetate decarboxylase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the decarboxylation of oxaloacetate into pyruvate. Seems to play a role in maintaining cellular concentrations of bicarbonate and pyruvate.
messages: Homotetramer; dimer of dimers.

216142:LT40 RS06185
gene id: 216142:LT40_RS06185
uniprot id: A0A089YN93
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial histone-like protein family.
messages: Heterodimer of an alpha and a beta chain.
messages: This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.

216142:LT40 RS15755
gene id: 216142:LT40_RS15755
uniprot id: A0A089YZ81
names: Similarity
messages: Belongs to the SCO1/2 family.

216142:LT40 RS13400
gene id: 216142:LT40_RS13400
uniprot id: A0A089ZQX0
names: Function
names: Similarity
messages: Belongs to the protease inhibitor I39 (alpha-2-macroglobulin) family. Bacterial alpha-2-macroglobulin subfamily.
messages: Protects the bacterial cell from host peptidases.

216142:LT40 RS06470
gene id: 216142:LT40_RS06470
uniprot id: A0A089YND2
names: Similarity
messages: Belongs to the Nudix hydrolase family.

216142:LT40 RS18890
gene id: 216142:LT40_RS18890
uniprot id: A0A089YUZ3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

216142:LT40 RS19860
gene id: 216142:LT40_RS19860
uniprot id: A0A089ZRL3
names: Cofactor
names: Similarity
messages: Belongs to the DNA photolyase class-1 family.
messages: Belongs to the DNA photolyase family.
messages: Binds 1 FAD per subunit.

216142:LT40 RS18235
gene id: 216142:LT40_RS18235
uniprot id: A0A089YUJ4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 2 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

216142:LT40 RS11385
gene id: 216142:LT40_RS11385
uniprot id: A0A089YUD4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 1 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 13 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.

216142:LT40 RS14330
gene id: 216142:LT40_RS14330
uniprot id: A0A089ZR06
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatB family.
messages: Cell membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

216142:LT40 RS12975
gene id: 216142:LT40_RS12975
uniprot id: A0A089ZQV5
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

216142:LT40 RS12655
gene id: 216142:LT40_RS12655
uniprot id: A0A089YRH7
names: Cofactor
names: Function
messages: Accepts electrons from ETF and reduces ubiquinone.
messages: Binds 1 [4Fe-4S] cluster.

216142:LT40 RS12555
gene id: 216142:LT40_RS12555
uniprot id: A0A089YRF3
names: Similarity
messages: Belongs to the MQO family.

216142:LT40 RS08495
gene id: 216142:LT40_RS08495
uniprot id: A0A089ZQD9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the quinone-dependent D-lactate dehydrogenase family.
messages: Catalyzes the oxidation of D-lactate to pyruvate.
messages: Cell inner membrane

216142:LT40 RS03085
gene id: 216142:LT40_RS03085
uniprot id: A0A089YJA5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Membrane

216142:LT40 RS08080
gene id: 216142:LT40_RS08080
uniprot id: A0A089YSP7
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

216142:LT40 RS18395
gene id: 216142:LT40_RS18395
uniprot id: A0A089ZRF8
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

216142:LT40 RS15765
gene id: 216142:LT40_RS15765
uniprot id: A0A089YWP1
names: Subcellular Location Annotation
messages: Membrane

216142:LT40 RS10225
gene id: 216142:LT40_RS10225
uniprot id: A0A089YTQ8
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane
messages: Membrane

216142:LT40 RS08300
gene id: 216142:LT40_RS08300
uniprot id: A0A089YM19
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

216142:LT40 RS20300
gene id: 216142:LT40_RS20300
uniprot id: A0A089YT90
names: Similarity
messages: Belongs to the YkuD family.

216142:LT40 RS18195
gene id: 216142:LT40_RS18195
uniprot id: A0A089ZRF2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COQ7 family.
messages: Binds 2 iron ions per subunit.
messages: Catalyzes the hydroxylation of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol during ubiquinone biosynthesis.
messages: Cell membrane

216142:LT40 RS02275
gene id: 216142:LT40_RS02275
uniprot id: A0A089YRG2
names: Function
names: Similarity
messages: Belongs to the FlgM family.
messages: Responsible for the coupling of flagellin expression to flagellar assembly by preventing expression of the flagellin genes when a component of the middle class of proteins is defective. It negatively regulates flagellar genes by inhibiting the activity of FliA by directly binding to FliA.

216142:LT40 RS11350
gene id: 216142:LT40_RS11350
uniprot id: A0A089YW80
names: Cofactor
messages: Can also use Mn(2+) ion.

216142:LT40 RS00840
gene id: 216142:LT40_RS00840
uniprot id: A0A089YKC4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the pyridoxamine 5'-phosphate oxidase family.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

216142:LT40 RS03865
gene id: 216142:LT40_RS03865
uniprot id: A0A089ZPW6
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

216142:LT40 RS00510
gene id: 216142:LT40_RS00510
uniprot id: A0A089ZPJ0
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Component of the RNA degradosome, which is a multiprotein complex involved in RNA processing and mRNA degradation.
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

216142:LT40 RS18930
gene id: 216142:LT40_RS18930
uniprot id: A0A089YY89
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

216142:LT40 RS03215
gene id: 216142:LT40_RS03215
uniprot id: A0A089YLP3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial glucokinase family.
messages: Cytoplasm

216142:LT40 RS14810
gene id: 216142:LT40_RS14810
uniprot id: A0A089YW50
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

216142:LT40 RS17525
gene id: 216142:LT40_RS17525
uniprot id: A0A089YRS5
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.

216142:LT40 RS04520
gene id: 216142:LT40_RS04520
uniprot id: A0A089YMB7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm

216142:LT40 RS01750
gene id: 216142:LT40_RS01750
uniprot id: A0A089YIG8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IA subfamily.
messages: Cell membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system and for the release of the potassium ions to the cytoplasm.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

216142:LT40 RS15690
gene id: 216142:LT40_RS15690
uniprot id: A0A089YWM2
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

216142:LT40 RS13905
gene id: 216142:LT40_RS13905
uniprot id: A0A089YS83
names: Similarity
messages: Belongs to the MotB family.

216142:LT40 RS15240
gene id: 216142:LT40_RS15240
uniprot id: A0A089YSU9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

216142:LT40 RS15230
gene id: 216142:LT40_RS15230
uniprot id: A0A089YWC0
names: Similarity
messages: Belongs to the GMC oxidoreductase family.

216142:LT40 RS19715
gene id: 216142:LT40_RS19715
uniprot id: A0A089YSZ6
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. TatD-type hydrolase family.

216142:LT40 RS07220
gene id: 216142:LT40_RS07220
uniprot id: A0A089YS38
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MobA family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: The N-terminal domain determines nucleotide recognition and specific binding, while the C-terminal domain determines the specific binding to the target protein.
messages: Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor.

216142:LT40 RS04070
gene id: 216142:LT40_RS04070
uniprot id: A0A089YSG2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsQ/DivIB family. FtsQ subfamily.
messages: Cell inner membrane
messages: Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly.
messages: Part of a complex composed of FtsB, FtsL and FtsQ.

216142:LT40 RS02185
gene id: 216142:LT40_RS02185
uniprot id: A0A089YRE3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

216142:LT40 RS11100
gene id: 216142:LT40_RS11100
uniprot id: A0A089YU92
names: Subcellular Location Annotation
messages: Membrane

216142:LT40 RS04945
gene id: 216142:LT40_RS04945
uniprot id: A0A089YSY5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvC family.
messages: Binds 2 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer which binds Holliday junction (HJ) DNA. The HJ becomes 2-fold symmetrical on binding to RuvC with unstacked arms; it has a different conformation from HJ DNA in complex with RuvA. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair. Endonuclease that resolves HJ intermediates. Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction. The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'. Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange. HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

216142:LT40 RS05550
gene id: 216142:LT40_RS05550
uniprot id: A0A089YTA6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

216142:LT40 RS04735
gene id: 216142:LT40_RS04735
uniprot id: A0A089YSU0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I fumarase family.
messages: Catalyzes the reversible hydration of fumarate to (S)-malate.
messages: Homodimer.

216142:LT40 RS07110
gene id: 216142:LT40_RS07110
uniprot id: A0A089YLC1
names: Similarity
messages: Belongs to the ABC transporter superfamily.

216142:LT40 RS03685
gene id: 216142:LT40_RS03685
uniprot id: A0A089YS89
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

216142:LT40 RS11765
gene id: 216142:LT40_RS11765
uniprot id: A0A089YNQ1
names: Similarity
messages: Belongs to the peptidase S24 family.

216142:LT40 RS07910
gene id: 216142:LT40_RS07910
uniprot id: A0A089YUG5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

216142:LT40 RS09500
gene id: 216142:LT40_RS09500
uniprot id: A0A089YMK6
names: Subcellular Location Annotation
messages: Membrane

216142:LT40 RS04135
gene id: 216142:LT40_RS04135
uniprot id: A0A089YJT4
names: Subcellular Location Annotation
messages: Membrane

216142:LT40 RS20460
gene id: 216142:LT40_RS20460
uniprot id: A0A089YTB5
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CheB family.
messages: Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.
messages: Cytoplasm
messages: Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
messages: Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity.

216142:LT40 RS08410
gene id: 216142:LT40_RS08410
uniprot id: A0A089YUR0
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. GDP-mannose 4,6-dehydratase subfamily.
messages: Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6-deoxy-D-mannose.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

216142:LT40 RS18865
gene id: 216142:LT40_RS18865
uniprot id: A0A089Z0Y8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm

216142:LT40 RS12095
gene id: 216142:LT40_RS12095
uniprot id: A0A089YR67
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

216142:LT40 RS11995
gene id: 216142:LT40_RS11995
uniprot id: A0A089YWH8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

216142:LT40 RS01515
gene id: 216142:LT40_RS01515
uniprot id: A0A089YR19
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

216142:LT40 RS18630
gene id: 216142:LT40_RS18630
uniprot id: A0A089YY16
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

216142:LT40 RS12980
gene id: 216142:LT40_RS12980
uniprot id: A0A089YV71
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

216142:LT40 RS12695
gene id: 216142:LT40_RS12695
uniprot id: A0A089YV06
names: Cofactor
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.
messages: Binds 1 zinc ion per subunit.

216142:LT40 RS05505
gene id: 216142:LT40_RS05505
uniprot id: A0A089ZQ27
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

216142:LT40 RS17225
gene id: 216142:LT40_RS17225
uniprot id: A0A089YTZ4
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.

216142:LT40 RS11705
gene id: 216142:LT40_RS11705
uniprot id: A0A089YNP2
names: Similarity
messages: Belongs to the UxaA family.

216142:LT40 RS15295
gene id: 216142:LT40_RS15295
uniprot id: A0A089YYZ7
names: Similarity
messages: Belongs to the NtaA/SnaA/DszA monooxygenase family.

216142:LT40 RS09935
gene id: 216142:LT40_RS09935
uniprot id: A0A089YQ35
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

216142:LT40 RS09685
gene id: 216142:LT40_RS09685
uniprot id: A0A089YPY7
names: Similarity
names: Subunit
messages: Belongs to the glutaminase family.
messages: Homotetramer.

216142:LT40 RS16480
gene id: 216142:LT40_RS16480
uniprot id: A0A089YRA2
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

216142:LT40 RS19375
gene id: 216142:LT40_RS19375
uniprot id: A0A089YV65
names: Similarity
messages: Belongs to the peptidase S16 family.

216142:LT40 RS13985
gene id: 216142:LT40_RS13985
uniprot id: A0A089YS94
names: Function
names: Similarity
messages: Acts on ADP-mannose and ADP-glucose as well as ADP-ribose. Prevents glycogen biosynthesis. The reaction catalyzed by this enzyme is a limiting step of the gluconeogenic process.
messages: Belongs to the Nudix hydrolase family. NudF subfamily.

216142:LT40 RS06245
gene id: 216142:LT40_RS06245
uniprot id: A0A089YNA1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. NspC subfamily.
messages: Catalyzes the decarboxylation of carboxynorspermidine and carboxyspermidine.
messages: Cytoplasm
messages: Homodimer.

216142:LT40 RS03825
gene id: 216142:LT40_RS03825
uniprot id: A0A089YJM8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MlaE permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the ABC transporter complex MlaFEDB, which is involved in a phospholipid transport pathway that maintains lipid asymmetry in the outer membrane by retrograde trafficking of phospholipids from the outer membrane to the inner membrane. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (MlaF), two transmembrane proteins (MlaE), two cytoplasmic solute-binding proteins (MlaB) and six periplasmic solute-binding proteins (MlaD).

216142:LT40 RS09020
gene id: 216142:LT40_RS09020
uniprot id: A0A089YPN1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

216142:LT40 RS01115
gene id: 216142:LT40_RS01115
uniprot id: A0A089YKG2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the AspA/AstE family. Succinylglutamate desuccinylase subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Transforms N(2)-succinylglutamate into succinate and glutamate.

216142:LT40 RS00455
gene id: 216142:LT40_RS00455
uniprot id: A0A089YQJ9
names: Similarity
messages: Belongs to the Skp family.

216142:LT40 RS17410
gene id: 216142:LT40_RS17410
uniprot id: A0A089ZRC3
names: Similarity
messages: Belongs to the peptidase U62 family.

216142:LT40 RS10240
gene id: 216142:LT40_RS10240
uniprot id: A0A089YVL7
names: Subcellular Location Annotation
messages: Membrane

216142:LT40 RS00860
gene id: 216142:LT40_RS00860
uniprot id: A0A089YI22
names: Similarity
messages: Belongs to the ABC transporter superfamily.

216142:LT40 RS16145
gene id: 216142:LT40_RS16145
uniprot id: A0A089YWZ9
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

216142:LT40 RS15260
gene id: 216142:LT40_RS15260
uniprot id: A0A089YQG3
names: Function
names: Similarity
messages: Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage.
messages: Belongs to the Nudix hydrolase family. RppH subfamily.

216142:LT40 RS06145
gene id: 216142:LT40_RS06145
uniprot id: A0A089ZQ52
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

216142:LT40 RS11825
gene id: 216142:LT40_RS11825
uniprot id: A0A089YR28
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

216142:LT40 RS17205
gene id: 216142:LT40_RS17205
uniprot id: A0A089Z009
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HSP33 family.
messages: Cytoplasm
messages: Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress.
messages: Under oxidizing conditions two disulfide bonds are formed involving the reactive cysteines. Under reducing conditions zinc is bound to the reactive cysteines and the protein is inactive.

216142:LT40 RS03190
gene id: 216142:LT40_RS03190
uniprot id: A0A089YLN9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

216142:LT40 RS18495
gene id: 216142:LT40_RS18495
uniprot id: A0A089ZRG2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

216142:LT40 RS09760
gene id: 216142:LT40_RS09760
uniprot id: A0A089YTG9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

216142:LT40 RS04805
gene id: 216142:LT40_RS04805
uniprot id: A0A089YK72
names: Function
names: Similarity
names: Subunit
messages: ATPase required for the correct placement of the division site. Cell division inhibitors MinC and MinD act in concert to form an inhibitor capable of blocking formation of the polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings.
messages: Belongs to the ParA family. MinD subfamily.
messages: Interacts with MinC and FtsZ.

216142:LT40 RS00480
gene id: 216142:LT40_RS00480
uniprot id: A0A089YQK1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

216142:LT40 RS14670
gene id: 216142:LT40_RS14670
uniprot id: A0A089ZR19
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
messages: Cell inner membrane
messages: Forms a membrane-associated complex with FtsE.
messages: Membrane
messages: Part of the ABC transporter FtsEX involved in cellular division.

216142:LT40 RS11655
gene id: 216142:LT40_RS11655
uniprot id: A0A089YNN3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine-cytosine permease (2.A.39) family.
messages: Membrane

216142:LT40 RS12770
gene id: 216142:LT40_RS12770
uniprot id: A0A089YV18
names: Function
names: Similarity
messages: Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits).
messages: In the C-terminal section; belongs to the transpeptidase family.
messages: In the N-terminal section; belongs to the glycosyltransferase 51 family.

216142:LT40 RS04855
gene id: 216142:LT40_RS04855
uniprot id: A0A089YK85
names: Similarity
messages: Belongs to the UPF0434 family.

216142:LT40 RS12395
gene id: 216142:LT40_RS12395
uniprot id: A0A089ZQT4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IPP isomerase type 2 family.
messages: Cytoplasm
messages: Homooctamer. Dimer of tetramers.
messages: Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

216142:LT40 RS18620
gene id: 216142:LT40_RS18620
uniprot id: A0A089Z0T5
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

216142:LT40 RS18350
gene id: 216142:LT40_RS18350
uniprot id: A0A089YXX5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

216142:LT40 RS09420
gene id: 216142:LT40_RS09420
uniprot id: A0A089YMJ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

216142:LT40 RS00895
gene id: 216142:LT40_RS00895
uniprot id: A0A089YQS0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.
messages: In the C-terminal section; belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: In the N-terminal section; belongs to the MIP18 family.

216142:LT40 RS18470
gene id: 216142:LT40_RS18470
uniprot id: A0A089ZRG1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

216142:LT40 RS03170
gene id: 216142:LT40_RS03170
uniprot id: A0A089YS00
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

216142:LT40 RS05035
gene id: 216142:LT40_RS05035
uniprot id: A0A089ZQ11
names: Cofactor
names: Similarity
messages: Belongs to the MsrB Met sulfoxide reductase family.
messages: Binds 1 zinc ion per subunit. The zinc ion is important for the structural integrity of the protein.

216142:LT40 RS20350
gene id: 216142:LT40_RS20350
uniprot id: A0A089YT99
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein uS19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein uS19.

216142:LT40 RS16840
gene id: 216142:LT40_RS16840
uniprot id: A0A089YTT4
names: Similarity
messages: Belongs to the GppA/Ppx family.

216142:LT40 RS02590
gene id: 216142:LT40_RS02590
uniprot id: A0A089YPR1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmD/CycX/HelD family.
messages: Cell inner membrane
messages: Membrane
messages: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.

216142:LT40 RS11790
gene id: 216142:LT40_RS11790
uniprot id: A0A089YNQ5
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

216142:LT40 RS19180
gene id: 216142:LT40_RS19180
uniprot id: A0A089YYD7
names: Subcellular Location Annotation
messages: Membrane

216142:LT40 RS04055
gene id: 216142:LT40_RS04055
uniprot id: A0A089YQF1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

216142:LT40 RS03945
gene id: 216142:LT40_RS03945
uniprot id: A0A089YQD7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome b family.
messages: Binds 2 heme groups non-covalently.
messages: Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.
messages: Membrane
messages: The main subunits of complex b-c1 are: cytochrome b, cytochrome c1 and the Rieske protein.

216142:LT40 RS12750
gene id: 216142:LT40_RS12750
uniprot id: A0A089YP70
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

216142:LT40 RS01970
gene id: 216142:LT40_RS01970
uniprot id: A0A089ZPP4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LpxH family.
messages: Binds 2 Mn(2+) ions per subunit in a binuclear metal center.
messages: Cell inner membrane
messages: Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

216142:LT40 RS19750
gene id: 216142:LT40_RS19750
uniprot id: A0A089Z1D7
names: Cofactor
messages: Binds 1 Fe(2+) ion per subunit.

216142:LT40 RS16085
gene id: 216142:LT40_RS16085
uniprot id: A0A089YZG4
names: Function
names: Similarity
messages: Belongs to the ParB family.
messages: Involved in chromosome partition. Localize to both poles of the predivisional cell following completion of DNA replication. Binds to the DNA origin of replication.

216142:LT40 RS14395
gene id: 216142:LT40_RS14395
uniprot id: A0A089YQ36
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

216142:LT40 RS03495
gene id: 216142:LT40_RS03495
uniprot id: A0A089YQ71
names: Function
names: Similarity
messages: A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters.
messages: Belongs to the NifU family.

216142:LT40 RS19415
gene id: 216142:LT40_RS19415
uniprot id: A0A089YYH5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

216142:LT40 RS01455
gene id: 216142:LT40_RS01455
uniprot id: A0A089YKK8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

216142:LT40 RS11565
gene id: 216142:LT40_RS11565
uniprot id: A0A089YUG2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

216142:LT40 RS05445
gene id: 216142:LT40_RS05445
uniprot id: A0A089YT94
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

216142:LT40 RS06540
gene id: 216142:LT40_RS06540
uniprot id: A0A089ZQ66
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

216142:LT40 RS20195
gene id: 216142:LT40_RS20195
uniprot id: A0A089ZRM6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

216142:LT40 RS19955
gene id: 216142:LT40_RS19955
uniprot id: A0A089Z1H4
names: Similarity
messages: Belongs to the SOS response-associated peptidase family.

216142:LT40 RS15220
gene id: 216142:LT40_RS15220
uniprot id: A0A089YYY5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

216142:LT40 RS15965
gene id: 216142:LT40_RS15965
uniprot id: A0A089ZR66
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

216142:LT40 RS00550
gene id: 216142:LT40_RS00550
uniprot id: A0A089YK82
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SurE nucleotidase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Cytoplasm
messages: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.

216142:LT40 RS17020
gene id: 216142:LT40_RS17020
uniprot id: A0A089YTW5
names: Similarity
messages: Belongs to the glutamine synthetase family.

216142:LT40 RS03635
gene id: 216142:LT40_RS03635
uniprot id: A0A089YS79
names: Similarity
messages: Belongs to the bacterial solute-binding protein 5 family.

216142:LT40 RS11640
gene id: 216142:LT40_RS11640
uniprot id: A0A089YWB6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

216142:LT40 RS01060
gene id: 216142:LT40_RS01060
uniprot id: A0A089YI55
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 3 family.
messages: Periplasm

216142:LT40 RS12390
gene id: 216142:LT40_RS12390
uniprot id: A0A089YWQ3
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

216142:LT40 RS10305
gene id: 216142:LT40_RS10305
uniprot id: A0A089YN03
names: Similarity
messages: Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family.

216142:LT40 RS03550
gene id: 216142:LT40_RS03550
uniprot id: A0A089YJH7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

216142:LT40 RS05090
gene id: 216142:LT40_RS05090
uniprot id: A0A089YKD2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein SsuA/TauA family.
messages: Periplasm

216142:LT40 RS08145
gene id: 216142:LT40_RS08145
uniprot id: A0A089YM00
names: Function
names: Similarity
messages: Belongs to the cyanase family.
messages: Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide.

216142:LT40 RS04905
gene id: 216142:LT40_RS04905
uniprot id: A0A089YQY6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

216142:LT40 RS18990
gene id: 216142:LT40_RS18990
uniprot id: A0A089YV07
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAD-like hydrolase superfamily. PhnX family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Involved in phosphonate degradation.

216142:LT40 RS17470
gene id: 216142:LT40_RS17470
uniprot id: A0A089YXJ5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 3-hydroxyacyl-CoA dehydrogenase family. L-carnitine dehydrogenase subfamily.
messages: Catalyzes the NAD(+)-dependent oxidation of L-carnitine to 3-dehydrocarnitine.
messages: Cytoplasm
messages: Homodimer.

216142:LT40 RS17605
gene id: 216142:LT40_RS17605
uniprot id: A0A089YRT7
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.

216142:LT40 RS19840
gene id: 216142:LT40_RS19840
uniprot id: A0A089YYP0
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

216142:LT40 RS07335
gene id: 216142:LT40_RS07335
uniprot id: A0A089YU45
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

216142:LT40 RS09380
gene id: 216142:LT40_RS09380
uniprot id: A0A089YV54
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Maintains high levels of reduced glutathione.

216142:LT40 RS19855
gene id: 216142:LT40_RS19855
uniprot id: A0A089Z1F6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PagL family.
messages: Cell outer membrane
messages: Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety.
messages: Homodimer.

216142:LT40 RS09040
gene id: 216142:LT40_RS09040
uniprot id: A0A089YMD1
names: Similarity
messages: Belongs to the PhzF family.

216142:LT40 RS14265
gene id: 216142:LT40_RS14265
uniprot id: A0A089YQ14
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.

216142:LT40 RS15550
gene id: 216142:LT40_RS15550
uniprot id: A0A089YT02
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

216142:LT40 RS08535
gene id: 216142:LT40_RS08535
uniprot id: A0A089YPH3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

216142:LT40 RS03290
gene id: 216142:LT40_RS03290
uniprot id: A0A089YLQ7
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

216142:LT40 RS06840
gene id: 216142:LT40_RS06840
uniprot id: A0A089YL71
names: Function
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.
messages: Catalyzes the isomerization of citrate to isocitrate via cis-aconitate.

216142:LT40 RS04440
gene id: 216142:LT40_RS04440
uniprot id: A0A089YJY9
names: Similarity
messages: Belongs to the glycosyl hydrolase 3 family.

216142:LT40 RS02350
gene id: 216142:LT40_RS02350
uniprot id: A0A089YL47
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Secreted

216142:LT40 RS00930
gene id: 216142:LT40_RS00930
uniprot id: A0A089YNX4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

216142:LT40 RS08865
gene id: 216142:LT40_RS08865
uniprot id: A0A089YUW2
names: Caution
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-I family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

216142:LT40 RS13515
gene id: 216142:LT40_RS13515
uniprot id: A0A089YS24
names: Function
names: Similarity
messages: Belongs to the CbiD family.
messages: Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A.

216142:LT40 RS10345
gene id: 216142:LT40_RS10345
uniprot id: A0A089ZQK8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

216142:LT40 RS17855
gene id: 216142:LT40_RS17855
uniprot id: A0A089Z0C8
names: Function
names: Similarity
messages: Belongs to the PqqB family.
messages: May be involved in the transport of PQQ or its precursor to the periplasm.

216142:LT40 RS11250
gene id: 216142:LT40_RS11250
uniprot id: A0A089ZQP1
names: Function
names: Similarity
messages: Belongs to the precorrin methyltransferase family.
messages: In the C-terminal section; belongs to the precorrin methyltransferase family.
messages: In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family.
messages: Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme.

216142:LT40 RS14495
gene id: 216142:LT40_RS14495
uniprot id: A0A089YQ53
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the BPG-independent phosphoglycerate mutase family.
messages: Binds 2 manganese ions per subunit.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: Monomer.

216142:LT40 RS17305
gene id: 216142:LT40_RS17305
uniprot id: A0A089Z027
names: Subcellular Location Annotation
messages: Membrane

216142:LT40 RS00990
gene id: 216142:LT40_RS00990
uniprot id: A0A089YNY2
names: Subcellular Location Annotation
messages: Membrane

216142:LT40 RS08785
gene id: 216142:LT40_RS08785
uniprot id: A0A089YT08
names: Similarity
messages: Belongs to the peptidase C40 family.

216142:LT40 RS02495
gene id: 216142:LT40_RS02495
uniprot id: A0A089YIY8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTP-binding SRP family.
messages: Cell membrane
messages: Membrane
messages: Necessary for flagellar biosynthesis. May be involved in translocation of the flagellum.

216142:LT40 RS12480
gene id: 216142:LT40_RS12480
uniprot id: A0A089YWR7
names: Similarity
messages: Belongs to the FAD-dependent urate hydroxylase family.

216142:LT40 RS13500
gene id: 216142:LT40_RS13500
uniprot id: A0A089ZQX4
names: Similarity
messages: Belongs to the CobH/CbiC family.

216142:LT40 RS11380
gene id: 216142:LT40_RS11380
uniprot id: A0A089ZQP6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the complex I 75 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: Composed of 13 different subunits. Subunits NuoCD, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

216142:LT40 RS08105
gene id: 216142:LT40_RS08105
uniprot id: A0A089YUM2
names: Similarity
messages: Belongs to the DapA family.

216142:LT40 RS05915
gene id: 216142:LT40_RS05915
uniprot id: A0A089YTF2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the heat shock protein 90 family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Molecular chaperone. Has ATPase activity.

216142:LT40 RS20675
gene id: 216142:LT40_RS20675
uniprot id: A0A089YVU0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

216142:LT40 RS19585
gene id: 216142:LT40_RS19585
uniprot id: A0A089ZRK3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A24 family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Plays an essential role in type IV pili and type II pseudopili formation by proteolytically removing the leader sequence from substrate proteins and subsequently monomethylating the alpha-amino group of the newly exposed N-terminal phenylalanine.

216142:LT40 RS09810
gene id: 216142:LT40_RS09810
uniprot id: A0A089YVD3
names: Similarity
messages: Belongs to the aldose epimerase family.

216142:LT40 RS00640
gene id: 216142:LT40_RS00640
uniprot id: A0A089YNT1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methylthiotransferase family. RimO subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein uS12.
messages: Cytoplasm

216142:LT40 RS19150
gene id: 216142:LT40_RS19150
uniprot id: A0A089ZRI7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LamB/PxpA family.
messages: Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.
messages: Forms a complex composed of PxpA, PxpB and PxpC.

216142:LT40 RS16655
gene id: 216142:LT40_RS16655
uniprot id: A0A089YRC9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

216142:LT40 RS18590
gene id: 216142:LT40_RS18590
uniprot id: A0A089Z0S8
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

216142:LT40 RS00430
gene id: 216142:LT40_RS00430
uniprot id: A0A089YQJ5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with (2E,6E)-farnesyl diphosphate (E,E-FPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E,38E)-undecaprenyl diphosphate (di-trans,octa-cis-UPP). UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

216142:LT40 RS13270
gene id: 216142:LT40_RS13270
uniprot id: A0A089YX73
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

216142:LT40 RS19830
gene id: 216142:LT40_RS19830
uniprot id: A0A089Z1F1
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

216142:LT40 RS06725
gene id: 216142:LT40_RS06725
uniprot id: A0A089YTU3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobS family.
messages: Cell membrane
messages: Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.
messages: Membrane

216142:LT40 RS02465
gene id: 216142:LT40_RS02465
uniprot id: A0A089YPN6
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliO/MopB family.
messages: Cell membrane

216142:LT40 RS16400
gene id: 216142:LT40_RS16400
uniprot id: A0A089YX37
names: Function
messages: This protein is a positive regulator for the phosphate regulon. Transcription of this operon is positively regulated by PhoB and PhoR when phosphate is limited.

216142:LT40 RS13570
gene id: 216142:LT40_RS13570
uniprot id: A0A089YY53
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the urease gamma subunit family.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

216142:LT40 RS16450
gene id: 216142:LT40_RS16450
uniprot id: A0A089YX44
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

216142:LT40 RS03590
gene id: 216142:LT40_RS03590
uniprot id: A0A089ZPV5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseA family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

216142:LT40 RS02115
gene id: 216142:LT40_RS02115
uniprot id: A0A089ZPP9
names: Similarity
names: Subunit
messages: Belongs to the bacterial histone-like protein family.
messages: Heterodimer of an alpha and a beta chain.

216142:LT40 RS07225
gene id: 216142:LT40_RS07225
uniprot id: A0A089YLD7
names: Function
names: Similarity
messages: Belongs to the MoaB/Mog family.
messages: May be involved in the biosynthesis of molybdopterin.

216142:LT40 RS07905
gene id: 216142:LT40_RS07905
uniprot id: A0A089YP44
names: Similarity
messages: Belongs to the OsmC/Ohr family.

216142:LT40 RS11645
gene id: 216142:LT40_RS11645
uniprot id: A0A089ZQQ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

216142:LT40 RS04215
gene id: 216142:LT40_RS04215
uniprot id: A0A089YM53
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

216142:LT40 RS17825
gene id: 216142:LT40_RS17825
uniprot id: A0A089YUA9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase group 1 family.
messages: Cell membrane
messages: Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP-Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A.

216142:LT40 RS00435
gene id: 216142:LT40_RS00435
uniprot id: A0A089ZPI7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

216142:LT40 RS14745
gene id: 216142:LT40_RS14745
uniprot id: A0A089YYQ4
names: Function
names: Similarity
messages: Belongs to the dihydrofolate reductase family.
messages: Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.

216142:LT40 RS00905
gene id: 216142:LT40_RS00905
uniprot id: A0A089YNX0
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dCTP deaminase family.
messages: Catalyzes the deamination of dCTP to dUTP.
messages: Homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

216142:LT40 RS00070
gene id: 216142:LT40_RS00070
uniprot id: A0A089YK14
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. CmoB family.
messages: Catalyzes carboxymethyl transfer from carboxy-S-adenosyl-L-methionine (Cx-SAM) to 5-hydroxyuridine (ho5U) to form 5-carboxymethoxyuridine (cmo5U) at position 34 in tRNAs.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

216142:LT40 RS14270
gene id: 216142:LT40_RS14270
uniprot id: A0A089YSE0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

216142:LT40 RS04630
gene id: 216142:LT40_RS04630
uniprot id: A0A089YSR8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Membrane

216142:LT40 RS03675
gene id: 216142:LT40_RS03675
uniprot id: A0A089YJK1
names: Subcellular Location Annotation
messages: Membrane

216142:LT40 RS09570
gene id: 216142:LT40_RS09570
uniprot id: A0A089YTD2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial microcompartment
messages: Belongs to the EutB family.
messages: Binds between the large and small subunits.
messages: Catalyzes the deamination of various vicinal amino-alcohols to oxo compounds. Allows this organism to utilize ethanolamine as the sole source of nitrogen and carbon in the presence of vitamin B12.
messages: The basic unit is a heterodimer which dimerizes to form tetramers. The heterotetramers trimerize; 6 large subunits form a core ring with 6 small subunits projecting outwards.

216142:LT40 RS14615
gene id: 216142:LT40_RS14615
uniprot id: A0A089YYN3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AB hydrolase superfamily. MetX family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine.

216142:LT40 RS11445
gene id: 216142:LT40_RS11445
uniprot id: A0A089YNK3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

216142:LT40 RS02470
gene id: 216142:LT40_RS02470
uniprot id: A0A089YIY1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliP/MopC/SpaP family.
messages: Cell membrane
messages: Membrane
messages: Plays a role in the flagellum-specific transport system.

216142:LT40 RS03105
gene id: 216142:LT40_RS03105
uniprot id: A0A089YQ15
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YejK family.
messages: nucleoid

216142:LT40 RS11975
gene id: 216142:LT40_RS11975
uniprot id: A0A089ZQR8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Membrane

216142:LT40 RS20340
gene id: 216142:LT40_RS20340
uniprot id: A0A089ZRN1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. SRP is a ribonucleoprotein composed of Ffh and a 4.5S RNA molecule.

216142:LT40 RS18535
gene id: 216142:LT40_RS18535
uniprot id: A0A089YUQ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

216142:LT40 RS02910
gene id: 216142:LT40_RS02910
uniprot id: A0A089YLJ2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

216142:LT40 RS05590
gene id: 216142:LT40_RS05590
uniprot id: A0A089YKN8
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

216142:LT40 RS18065
gene id: 216142:LT40_RS18065
uniprot id: A0A089ZRE7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GlpE family.
messages: Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide.
messages: Cytoplasm

216142:LT40 RS00410
gene id: 216142:LT40_RS00410
uniprot id: A0A089ZPI6
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

216142:LT40 RS13100
gene id: 216142:LT40_RS13100
uniprot id: A0A089YV97
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

216142:LT40 RS00105
gene id: 216142:LT40_RS00105
uniprot id: A0A089ZPH5
names: Cofactor
names: Similarity
messages: Belongs to the truncated hemoglobin family. Group I subfamily.
messages: Binds 1 heme group per subunit.

216142:LT40 RS01840
gene id: 216142:LT40_RS01840
uniprot id: A0A089YR72
names: Similarity
messages: Belongs to the YkuD family.

216142:LT40 RS03515
gene id: 216142:LT40_RS03515
uniprot id: A0A089ZPV2
names: Similarity
messages: Belongs to the adrenodoxin/putidaredoxin family.

216142:LT40 RS15630
gene id: 216142:LT40_RS15630
uniprot id: A0A089YZ53
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family. GltP subfamily.
messages: Catalyzes the proton-dependent transport of glutamate and aspartate.
messages: Cell inner membrane
messages: Membrane

216142:LT40 RS16070
gene id: 216142:LT40_RS16070
uniprot id: A0A089YWX5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

216142:LT40 RS13235
gene id: 216142:LT40_RS13235
uniprot id: A0A089YPH2
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

216142:LT40 RS14735
gene id: 216142:LT40_RS14735
uniprot id: A0A089YQ93
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

216142:LT40 RS20270
gene id: 216142:LT40_RS20270
uniprot id: A0A089YVK1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: In the N-terminal section; belongs to the FGAMS family.
messages: Monomer.
messages: Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.

216142:LT40 RS05160
gene id: 216142:LT40_RS05160
uniprot id: A0A089ZQ15
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

216142:LT40 RS17270
gene id: 216142:LT40_RS17270
uniprot id: A0A089YRN2
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

216142:LT40 RS19530
gene id: 216142:LT40_RS19530
uniprot id: A0A089YV88
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

216142:LT40 RS08015
gene id: 216142:LT40_RS08015
uniprot id: A0A089ZQC1
names: Activity Regulation
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.
messages: Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.
messages: Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate.

216142:LT40 RS19445
gene id: 216142:LT40_RS19445
uniprot id: A0A089YSV6
names: Function
names: Similarity
messages: Belongs to the ribF family.
messages: Catalyzes the phosphorylation of riboflavin to FMN followed by the adenylation of FMN to FAD.

216142:LT40 RS03875
gene id: 216142:LT40_RS03875
uniprot id: A0A089YJN8
names: Function
messages: Might be efficient in the degradation of transiently denatured and unfolded proteins which accumulate in the periplasm following stress conditions.

216142:LT40 RS04295
gene id: 216142:LT40_RS04295
uniprot id: A0A089YSK0
names: Function
names: Similarity
messages: Belongs to the PurU family.
messages: Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).

216142:LT40 RS19820
gene id: 216142:LT40_RS19820
uniprot id: A0A089YT15
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LolB family.
messages: Cell outer membrane
messages: Membrane
messages: Monomer.
messages: Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein.

216142:LT40 RS19800
gene id: 216142:LT40_RS19800
uniprot id: A0A089Z1E6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

216142:LT40 RS08160
gene id: 216142:LT40_RS08160
uniprot id: A0A089ZQC6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Membrane

216142:LT40 RS18070
gene id: 216142:LT40_RS18070
uniprot id: A0A089YXS9
names: Function
names: Similarity
messages: Belongs to the Ap4A hydrolase family.
messages: Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP.

216142:LT40 RS18150
gene id: 216142:LT40_RS18150
uniprot id: A0A089YXU5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

216142:LT40 RS02685
gene id: 216142:LT40_RS02685
uniprot id: A0A089YRS1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

216142:LT40 RS06665
gene id: 216142:LT40_RS06665
uniprot id: A0A089YL46
names: Similarity
messages: Belongs to the peptidase C40 family.

216142:LT40 RS13750
gene id: 216142:LT40_RS13750
uniprot id: A0A089ZQY4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. RlmB subfamily.
messages: Cytoplasm
messages: Specifically methylates the ribose of guanosine 2251 in 23S rRNA.

216142:LT40 RS15130
gene id: 216142:LT40_RS15130
uniprot id: A0A089YWA0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Membrane

216142:LT40 RS11540
gene id: 216142:LT40_RS11540
uniprot id: A0A089YUF7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

216142:LT40 RS18975
gene id: 216142:LT40_RS18975
uniprot id: A0A089ZRI0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

216142:LT40 RS05575
gene id: 216142:LT40_RS05575
uniprot id: A0A089YTB0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 1 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

216142:LT40 RS14530
gene id: 216142:LT40_RS14530
uniprot id: A0A089YSH9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

216142:LT40 RS12865
gene id: 216142:LT40_RS12865
uniprot id: A0A089ZQV1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Component of the RNA degradosome, which is a multiprotein complex involved in RNA processing and mRNA degradation.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

216142:LT40 RS12410
gene id: 216142:LT40_RS12410
uniprot id: A0A089YRC7
names: Similarity
messages: Belongs to the carotenoid/retinoid oxidoreductase family.

216142:LT40 RS09740
gene id: 216142:LT40_RS09740
uniprot id: A0A089YMP1
names: Similarity
messages: Belongs to the glycerate kinase type-1 family.

216142:LT40 RS13275
gene id: 216142:LT40_RS13275
uniprot id: A0A089ZQW5
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

216142:LT40 RS11770
gene id: 216142:LT40_RS11770
uniprot id: A0A089YR21
names: Similarity
messages: Belongs to the SOS response-associated peptidase family.

216142:LT40 RS14655
gene id: 216142:LT40_RS14655
uniprot id: A0A089YQ79
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0382 family.
messages: Membrane

216142:LT40 RS03480
gene id: 216142:LT40_RS03480
uniprot id: A0A089YLT2
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

216142:LT40 RS05565
gene id: 216142:LT40_RS05565
uniprot id: A0A089YKN4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

216142:LT40 RS08810
gene id: 216142:LT40_RS08810
uniprot id: A0A089ZQF1
names: Similarity
messages: Belongs to the glycosyl hydrolase 24 family.

216142:LT40 RS02050
gene id: 216142:LT40_RS02050
uniprot id: A0A089ZPP7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

216142:LT40 RS18365
gene id: 216142:LT40_RS18365
uniprot id: A0A089Z0M0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

216142:LT40 RS17285
gene id: 216142:LT40_RS17285
uniprot id: A0A089ZRB8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the agmatine deiminase family.
messages: Homodimer.
messages: Mediates the hydrolysis of agmatine into N-carbamoylputrescine in the arginine decarboxylase (ADC) pathway of putrescine biosynthesis, a basic polyamine.

216142:LT40 RS11370
gene id: 216142:LT40_RS11370
uniprot id: A0A089YQW7
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

216142:LT40 RS01195
gene id: 216142:LT40_RS01195
uniprot id: A0A089YP13
names: Subcellular Location Annotation
messages: Membrane

216142:LT40 RS16015
gene id: 216142:LT40_RS16015
uniprot id: A0A089ZR68
names: Similarity
messages: Belongs to the GMC oxidoreductase family.

216142:LT40 RS13815
gene id: 216142:LT40_RS13815
uniprot id: A0A089YVP3
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

216142:LT40 RS13350
gene id: 216142:LT40_RS13350
uniprot id: A0A089ZQW8
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

216142:LT40 RS01140
gene id: 216142:LT40_RS01140
uniprot id: A0A089YKG6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Mediates global changes in gene expression, shifting from rapid growth to stress survival by linking envelope stress, the stringent response and the catabolite repression systems. Usually binds in the 5'-UTR; binding at or near the Shine-Dalgarno sequence prevents ribosome-binding, repressing translation, binding elsewhere in the 5'-UTR can activate translation and/or stabilize the mRNA. Its function is antagonized by small RNA(s).
messages: Belongs to the CsrA/RsmA family.
messages: Cytoplasm
messages: Homodimer; the beta-strands of each monomer intercalate to form a hydrophobic core, while the alpha-helices form wings that extend away from the core.

216142:LT40 RS14820
gene id: 216142:LT40_RS14820
uniprot id: A0A089YSM3
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

216142:LT40 RS07995
gene id: 216142:LT40_RS07995
uniprot id: A0A089YSM4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
messages: Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
messages: Cytoplasm

216142:LT40 RS04910
gene id: 216142:LT40_RS04910
uniprot id: A0A089YK97
names: Similarity
messages: Belongs to the SlyX family.

216142:LT40 RS12645
gene id: 216142:LT40_RS12645
uniprot id: A0A089YUZ2
names: Cofactor
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.
messages: Binds 1 FAD per dimer.

216142:LT40 RS16695
gene id: 216142:LT40_RS16695
uniprot id: A0A089ZR95
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

216142:LT40 RS15895
gene id: 216142:LT40_RS15895
uniprot id: A0A089YWS4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

216142:LT40 RS06710
gene id: 216142:LT40_RS06710
uniprot id: A0A089YRU3
names: Function
names: Similarity
messages: Belongs to the CobU/CobP family.
messages: Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate.

216142:LT40 RS11235
gene id: 216142:LT40_RS11235
uniprot id: A0A089YNH6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. MoaA family.
messages: Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.
messages: Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
messages: Monomer and homodimer.

216142:LT40 RS15770
gene id: 216142:LT40_RS15770
uniprot id: A0A089YQS6
names: Function
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

216142:LT40 RS11410
gene id: 216142:LT40_RS11410
uniprot id: A0A089YUD9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Membrane

216142:LT40 RS06140
gene id: 216142:LT40_RS06140
uniprot id: A0A089YTJ3
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

216142:LT40 RS21900
gene id: 216142:LT40_RS21900
uniprot id: A0A089YMJ4
names: Subcellular Location Annotation
messages: Cytoplasm

216142:LT40 RS17000
gene id: 216142:LT40_RS17000
uniprot id: A0A089YZX2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein SsuA/TauA family.
messages: Periplasm

216142:LT40 RS17570
gene id: 216142:LT40_RS17570
uniprot id: A0A089ZRC9
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

216142:LT40 RS02595
gene id: 216142:LT40_RS02595
uniprot id: A0A089YJ09
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmE/CycJ family.
messages: Cell membrane
messages: Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH.

216142:LT40 RS06565
gene id: 216142:LT40_RS06565
uniprot id: A0A089ZQ67
names: Subcellular Location Annotation
messages: Membrane

216142:LT40 RS05025
gene id: 216142:LT40_RS05025
uniprot id: A0A089YML6
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Membrane

216142:LT40 RS05735
gene id: 216142:LT40_RS05735
uniprot id: A0A089YTC7
names: Subcellular Location Annotation
messages: Cell inner membrane

216142:LT40 RS18745
gene id: 216142:LT40_RS18745
uniprot id: A0A089ZRH1
names: Function
names: Similarity
messages: Belongs to the UbiX/PAD1 family.
messages: Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN.

216142:LT40 RS08155
gene id: 216142:LT40_RS08155
uniprot id: A0A089YUM7
names: Similarity
messages: Belongs to the DapA family.

216142:LT40 RS18020
gene id: 216142:LT40_RS18020
uniprot id: A0A089YXR9
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

216142:LT40 RS08825
gene id: 216142:LT40_RS08825
uniprot id: A0A089YPK9
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

216142:LT40 RS13245
gene id: 216142:LT40_RS13245
uniprot id: A0A089YX66
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

216142:LT40 RS05140
gene id: 216142:LT40_RS05140
uniprot id: A0A089YR30
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

216142:LT40 RS18780
gene id: 216142:LT40_RS18780
uniprot id: A0A089YSK1
names: Similarity
messages: Belongs to the DNA glycosylase MPG family.

216142:LT40 RS04895
gene id: 216142:LT40_RS04895
uniprot id: A0A089YSX5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.
messages: Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.
messages: Cytoplasm
messages: Homodimer.

216142:LT40 RS00710
gene id: 216142:LT40_RS00710
uniprot id: A0A089YKA4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

216142:LT40 RS15950
gene id: 216142:LT40_RS15950
uniprot id: A0A089YQW6
names: Similarity
messages: Belongs to the DprA/Smf family.

216142:LT40 RS02460
gene id: 216142:LT40_RS02460
uniprot id: A0A089ZPR2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliN/MopA/SpaO family.
messages: Cell membrane
messages: FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
messages: Membrane

216142:LT40 RS16065
gene id: 216142:LT40_RS16065
uniprot id: A0A089ZR70
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
messages: Binds 1 potassium ion per subunit.
messages: Cytoplasm
messages: Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

216142:LT40 RS02160
gene id: 216142:LT40_RS02160
uniprot id: A0A089YRD6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Monomer.
messages: Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl-glutathione to form glutathione and D-lactic acid.

216142:LT40 RS20745
gene id: 216142:LT40_RS20745
uniprot id: A0A089YTH5
names: Similarity
messages: Belongs to the UPF0337 (CsbD) family.

216142:LT40 RS14630
gene id: 216142:LT40_RS14630
uniprot id: A0A089YQ74
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

216142:LT40 RS03555
gene id: 216142:LT40_RS03555
uniprot id: A0A089YLU4
names: Similarity
messages: Belongs to the YfgM family.

216142:LT40 RS00565
gene id: 216142:LT40_RS00565
uniprot id: A0A089YNS1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoS subfamily.
messages: Cytoplasm
messages: Interacts with the RNA polymerase core enzyme.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the master transcriptional regulator of the stationary phase and the general stress response.

216142:LT40 RS10355
gene id: 216142:LT40_RS10355
uniprot id: A0A089YTT5
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

216142:LT40 RS05170
gene id: 216142:LT40_RS05170
uniprot id: A0A089YKE9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell inner membrane
messages: Membrane

216142:LT40 RS03120
gene id: 216142:LT40_RS03120
uniprot id: A0A089YRZ3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

216142:LT40 RS19070
gene id: 216142:LT40_RS19070
uniprot id: A0A089Z121
names: Function
names: Similarity
messages: Belongs to the NtaA/SnaA/DszA monooxygenase family. RutA subfamily.
messages: Catalyzes the pyrimidine ring opening between N-3 and C-4 by an unusual flavin hydroperoxide-catalyzed mechanism, adding oxygen atoms in the process to yield ureidoacrylate peracid, that immediately reacts with FMN forming ureidoacrylate and FMN-N(5)-oxide. The FMN-N(5)-oxide reacts spontaneously with NADH to produce FMN. Requires the flavin reductase RutF to regenerate FMN in vivo.

216142:LT40 RS19975
gene id: 216142:LT40_RS19975
uniprot id: A0A089YVE9
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

216142:LT40 RS09345
gene id: 216142:LT40_RS09345
uniprot id: A0A089YMI2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LRR-containing bacterial E3 ligase family.
messages: Host cytoplasm
messages: Secreted

216142:LT40 RS00590
gene id: 216142:LT40_RS00590
uniprot id: A0A089YNS5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecX family.
messages: Cytoplasm
messages: Modulates RecA activity.

216142:LT40 RS12285
gene id: 216142:LT40_RS12285
uniprot id: A0A089YR98
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

216142:LT40 RS00160
gene id: 216142:LT40_RS00160
uniprot id: A0A089YNM0
names: Subcellular Location Annotation
messages: Cytoplasm

216142:LT40 RS13450
gene id: 216142:LT40_RS13450
uniprot id: A0A089ZQX2
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

216142:LT40 RS02135
gene id: 216142:LT40_RS02135
uniprot id: A0A089YRD1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

216142:LT40 RS01405
gene id: 216142:LT40_RS01405
uniprot id: A0A089YR05
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

216142:LT40 RS19425
gene id: 216142:LT40_RS19425
uniprot id: A0A089YV72
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

216142:LT40 RS04950
gene id: 216142:LT40_RS04950
uniprot id: A0A089ZQ08
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvA family.
messages: Cytoplasm
messages: Has three domains with a flexible linker between the domains II and III and assumes an 'L' shape. Domain III is highly mobile and contacts RuvB.
messages: Homotetramer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

216142:LT40 RS10445
gene id: 216142:LT40_RS10445
uniprot id: A0A089YQD5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

216142:LT40 RS01070
gene id: 216142:LT40_RS01070
uniprot id: A0A089YQV1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane

216142:LT40 RS01410
gene id: 216142:LT40_RS01410
uniprot id: A0A089ZPM3
names: Subcellular Location Annotation
messages: Membrane

216142:LT40 RS01545
gene id: 216142:LT40_RS01545
uniprot id: A0A089ZPM8
names: Similarity
messages: Belongs to the bleomycin resistance protein family.

216142:LT40 RS16295
gene id: 216142:LT40_RS16295
uniprot id: A0A089ZR79
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsuA/YedE (TC 9.B.102) family.
messages: Cell inner membrane
messages: Membrane

216142:LT40 RS13790
gene id: 216142:LT40_RS13790
uniprot id: A0A089YVP0
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. HisZ subfamily.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine.
messages: This function is generally fulfilled by the C-terminal part of HisG, which is missing in some bacteria such as this one.

216142:LT40 RS13440
gene id: 216142:LT40_RS13440
uniprot id: A0A089YS13
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbD subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps.

216142:LT40 RS14815
gene id: 216142:LT40_RS14815
uniprot id: A0A089YQA3
names: Cofactor
names: Similarity
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.

216142:LT40 RS17655
gene id: 216142:LT40_RS17655
uniprot id: A0A089YRU4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 3 lipoyl cofactors covalently.
messages: Forms a 24-polypeptide structural core with octahedral symmetry.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).

216142:LT40 RS02425
gene id: 216142:LT40_RS02425
uniprot id: A0A089YL63
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliJ family.
messages: Cell membrane
messages: Membrane

216142:LT40 RS13875
gene id: 216142:LT40_RS13875
uniprot id: A0A089YPV7
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

216142:LT40 RS01755
gene id: 216142:LT40_RS01755
uniprot id: A0A089YKR4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KdpC family.
messages: Cell membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

216142:LT40 RS06410
gene id: 216142:LT40_RS06410
uniprot id: A0A089YRQ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

216142:LT40 RS01980
gene id: 216142:LT40_RS01980
uniprot id: A0A089YIL7
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

216142:LT40 RS03845
gene id: 216142:LT40_RS03845
uniprot id: A0A089YQC3
names: Similarity
messages: Belongs to the BolA/IbaG family.

216142:LT40 RS11135
gene id: 216142:LT40_RS11135
uniprot id: A0A089YQS8
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit B family.

216142:LT40 RS13175
gene id: 216142:LT40_RS13175
uniprot id: A0A089ZQW2
names: Similarity
messages: Belongs to the HIBADH-related family.

216142:LT40 RS16495
gene id: 216142:LT40_RS16495
uniprot id: A0A089ZR87
names: Similarity
messages: Belongs to the YicC/YloC family.

216142:LT40 RS14380
gene id: 216142:LT40_RS14380
uniprot id: A0A089ZR08
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S33 family.
messages: Cytoplasm

216142:LT40 RS04810
gene id: 216142:LT40_RS04810
uniprot id: A0A089YMH7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MinC family.
messages: Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization.
messages: Interacts with MinD and FtsZ.

216142:LT40 RS18705
gene id: 216142:LT40_RS18705
uniprot id: A0A089YSF9
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

216142:LT40 RS10440
gene id: 216142:LT40_RS10440
uniprot id: A0A089YN30
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

216142:LT40 RS03625
gene id: 216142:LT40_RS03625
uniprot id: A0A089YJJ1
names: Similarity
messages: Belongs to the bacterial solute-binding protein 5 family.

216142:LT40 RS00535
gene id: 216142:LT40_RS00535
uniprot id: A0A089ZPJ1
names: Function
names: Similarity
messages: Belongs to the esterase D family.
messages: Serine hydrolase involved in the detoxification of formaldehyde.

216142:LT40 RS15175
gene id: 216142:LT40_RS15175
uniprot id: A0A089ZR37
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

216142:LT40 RS15735
gene id: 216142:LT40_RS15735
uniprot id: A0A089ZR57
names: Function
names: Similarity
messages: Belongs to the catalase family. HPII subfamily.
messages: Decomposes hydrogen peroxide into water and oxygen; serves to protect cells from the toxic effects of hydrogen peroxide.
messages: Serves to protect cells from the toxic effects of hydrogen peroxide.

216142:LT40 RS03080
gene id: 216142:LT40_RS03080
uniprot id: A0A089YQ10
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

216142:LT40 RS02015
gene id: 216142:LT40_RS02015
uniprot id: A0A089YKX1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

216142:LT40 RS08960
gene id: 216142:LT40_RS08960
uniprot id: A0A089YMB6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. ATZ/TRZ family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia.

216142:LT40 RS01710
gene id: 216142:LT40_RS01710
uniprot id: A0A089YR46
names: Similarity
messages: Belongs to the IlvD/Edd family.

216142:LT40 RS19225
gene id: 216142:LT40_RS19225
uniprot id: A0A089ZRJ0
names: Function
names: Similarity
messages: Belongs to the bacterial two-domain DSD family.
messages: Catalyzes the conversion of 3-dehydroshikimate to protocatechuate (3,4-dihydroxybenzoate), a common intermediate of quinate and shikimate degradation pathways.

216142:LT40 RS08170
gene id: 216142:LT40_RS08170
uniprot id: A0A089YM04
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

216142:LT40 RS19345
gene id: 216142:LT40_RS19345
uniprot id: A0A089YST9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

216142:LT40 RS09260
gene id: 216142:LT40_RS09260
uniprot id: A0A089ZQG7
names: Subcellular Location Annotation
messages: Membrane

216142:LT40 RS06600
gene id: 216142:LT40_RS06600
uniprot id: A0A089YTS2
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

216142:LT40 RS02270
gene id: 216142:LT40_RS02270
uniprot id: A0A089YL27
names: Function
names: Similarity
messages: Belongs to the FlgN family.
messages: Required for the efficient initiation of filament assembly.

216142:LT40 RS19785
gene id: 216142:LT40_RS19785
uniprot id: A0A089YYN1
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

216142:LT40 RS06685
gene id: 216142:LT40_RS06685
uniprot id: A0A089YRU0
names: Domain
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the CobB/CbiA family.
messages: Belongs to the CobB/CobQ family. CobQ subfamily.
messages: Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L-glutamine or ammonia as the nitrogen source.
messages: Comprises of two domains. The C-terminal domain contains the binding site for glutamine and catalyzes the hydrolysis of this substrate to glutamate and ammonia. The N-terminal domain is anticipated to bind ATP and hydrogenobyrinate and catalyzes the ultimate synthesis of the diamide product. The ammonia produced via the glutaminase domain is probably translocated to the adjacent domain via a molecular tunnel, where it reacts with an activated intermediate.
messages: The a and c carboxylates of hydrogenobyrinate are activated for nucleophilic attack via formation of a phosphorylated intermediate by ATP. CobB catalyzes first the amidation of the c-carboxylate, and then that of the a-carboxylate.

216142:LT40 RS18450
gene id: 216142:LT40_RS18450
uniprot id: A0A089YXZ3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

216142:LT40 RS06535
gene id: 216142:LT40_RS06535
uniprot id: A0A089YTR2
names: Subcellular Location Annotation
messages: Membrane

216142:LT40 RS12085
gene id: 216142:LT40_RS12085
uniprot id: A0A089YUN8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

216142:LT40 RS14785
gene id: 216142:LT40_RS14785
uniprot id: A0A089YW45
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

216142:LT40 RS13830
gene id: 216142:LT40_RS13830
uniprot id: A0A089YY92
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm

216142:LT40 RS10825
gene id: 216142:LT40_RS10825
uniprot id: A0A089ZQM5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane.

216142:LT40 RS13255
gene id: 216142:LT40_RS13255
uniprot id: A0A089YVC7
names: Similarity
messages: Belongs to the IMPACT family.

216142:LT40 RS11260
gene id: 216142:LT40_RS11260
uniprot id: A0A089YNH9
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fluoride channel Fluc/FEX (TC 1.A.43) family.
messages: Cell membrane
messages: Fluoride-specific ion channel. Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane
messages: Na(+) is not transported, but it plays an essential structural role and its presence is essential for fluoride channel function.

216142:LT40 RS11080
gene id: 216142:LT40_RS11080
uniprot id: A0A089YNF8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
messages: Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.
messages: Monomer.

216142:LT40 RS20115
gene id: 216142:LT40_RS20115
uniprot id: A0A089Z1J7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

216142:LT40 RS10030
gene id: 216142:LT40_RS10030
uniprot id: A0A089ZQJ6
names: Similarity
messages: Belongs to the EndA/NucM nuclease family.

216142:LT40 RS11095
gene id: 216142:LT40_RS11095
uniprot id: A0A089ZQN5
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

216142:LT40 RS16485
gene id: 216142:LT40_RS16485
uniprot id: A0A089YTM1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

216142:LT40 RS12605
gene id: 216142:LT40_RS12605
uniprot id: A0A089YRG5
names: Similarity
messages: Belongs to the citrate synthase family.

216142:LT40 RS02955
gene id: 216142:LT40_RS02955
uniprot id: A0A089YJ88
names: Similarity
messages: Belongs to the Cu-Zn superoxide dismutase family.

216142:LT40 RS16120
gene id: 216142:LT40_RS16120
uniprot id: A0A089YWZ4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

216142:LT40 RS12170
gene id: 216142:LT40_RS12170
uniprot id: A0A089YR79
names: Subcellular Location Annotation
messages: Membrane

216142:LT40 RS15750
gene id: 216142:LT40_RS15750
uniprot id: A0A089YT44
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NlpA lipoprotein family.
messages: Membrane

216142:LT40 RS19015
gene id: 216142:LT40_RS19015
uniprot id: A0A089YV11
names: Subcellular Location Annotation
messages: Membrane

216142:LT40 RS14660
gene id: 216142:LT40_RS14660
uniprot id: A0A089YSJ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 51 family.
messages: Cell inner membrane
messages: Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors.

216142:LT40 RS19020
gene id: 216142:LT40_RS19020
uniprot id: A0A089Z112
names: Similarity
messages: Belongs to the PrpF family.

216142:LT40 RS16055
gene id: 216142:LT40_RS16055
uniprot id: A0A089YTA2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RnpA family.
messages: Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.
messages: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.

216142:LT40 RS06605
gene id: 216142:LT40_RS06605
uniprot id: A0A089ZQ68
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. RlmD subfamily.
messages: Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA.

216142:LT40 RS02940
gene id: 216142:LT40_RS02940
uniprot id: A0A089YRW9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acetylates the N-terminal alanine of ribosomal protein bS18.
messages: Belongs to the acetyltransferase family. RimI subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

216142:LT40 RS05605
gene id: 216142:LT40_RS05605
uniprot id: A0A089ZQ31
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

216142:LT40 RS16600
gene id: 216142:LT40_RS16600
uniprot id: A0A089YX68
names: Function
names: Similarity
messages: Belongs to the DadA oxidoreductase family.
messages: Oxidative deamination of D-amino acids.

216142:LT40 RS18920
gene id: 216142:LT40_RS18920
uniprot id: A0A089Z0Z8
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

216142:LT40 RS10065
gene id: 216142:LT40_RS10065
uniprot id: A0A089YMV6
names: Similarity
messages: Belongs to the Gfa family.

216142:LT40 RS08025
gene id: 216142:LT40_RS08025
uniprot id: A0A089YLY2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Also exhibits azoreductase activity. Catalyzes the reductive cleavage of the azo bond in aromatic azo compounds to the corresponding amines.
messages: Belongs to the azoreductase type 1 family.
messages: Binds 1 FMN per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Quinone reductase that provides resistance to thiol-specific stress caused by electrophilic quinones.

216142:LT40 RS05770
gene id: 216142:LT40_RS05770
uniprot id: A0A089YRF8
names: Cofactor
names: Similarity
messages: Belongs to the nitroreductase family.
messages: Binds 1 FMN per subunit.

216142:LT40 RS04130
gene id: 216142:LT40_RS04130
uniprot id: A0A089YQG4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Cell inner membrane
messages: Homoheptamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mechanosensitive channel that participates in the regulation of osmotic pressure changes within the cell, opening in response to stretch forces in the membrane lipid bilayer, without the need for other proteins. Contributes to normal resistance to hypoosmotic shock. Forms an ion channel of 1.0 nanosiemens conductance with a slight preference for anions.
messages: Membrane

216142:LT40 RS18310
gene id: 216142:LT40_RS18310
uniprot id: A0A089YUK0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

216142:LT40 RS06845
gene id: 216142:LT40_RS06845
uniprot id: A0A089YNJ0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily.
messages: Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA.
messages: Cytoplasm
messages: Monomer.

216142:LT40 RS02110
gene id: 216142:LT40_RS02110
uniprot id: A0A089YRC4
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

216142:LT40 RS04705
gene id: 216142:LT40_RS04705
uniprot id: A0A089YST3
names: Subcellular Location Annotation
messages: Secreted

216142:LT40 RS16700
gene id: 216142:LT40_RS16700
uniprot id: A0A089YX85
names: Similarity
messages: Belongs to the UPF0047 family.

216142:LT40 RS00770
gene id: 216142:LT40_RS00770
uniprot id: A0A089YQP6
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S45 family.
messages: Binds 1 Ca(2+) ion per dimer.
messages: Periplasm

216142:LT40 RS03850
gene id: 216142:LT40_RS03850
uniprot id: A0A089YJN3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

216142:LT40 RS12000
gene id: 216142:LT40_RS12000
uniprot id: A0A089ZQR9
names: Similarity
messages: Belongs to the arginase family. Agmatinase subfamily.

216142:LT40 RS15945
gene id: 216142:LT40_RS15945
uniprot id: A0A089YWT3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SUA5 family. TsaC subfamily.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Catalyzes the conversion of L-threonine, HCO(3)(-)/CO(2) and ATP to give threonylcarbamoyl-AMP (TC-AMP) as the acyladenylate intermediate, with the release of diphosphate.

216142:LT40 RS11085
gene id: 216142:LT40_RS11085
uniprot id: A0A089YQS1
names: Similarity
messages: Belongs to the aminoglycoside phosphotransferase family.
messages: Belongs to the glycosyl hydrolase 13 family. TreS subfamily.

216142:LT40 RS04370
gene id: 216142:LT40_RS04370
uniprot id: A0A089YM87
names: Similarity
messages: Belongs to the outer membrane porin (Opr) (TC 1.B.25) family.

216142:LT40 RS03995
gene id: 216142:LT40_RS03995
uniprot id: A0A089YSE7
names: Similarity
messages: Belongs to the UPF0102 family.

216142:LT40 RS14710
gene id: 216142:LT40_RS14710
uniprot id: A0A089YQ88
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

216142:LT40 RS10140
gene id: 216142:LT40_RS10140
uniprot id: A0A089YTP1
names: Similarity
messages: Belongs to the phosphohexose mutase family.

216142:LT40 RS20565
gene id: 216142:LT40_RS20565
uniprot id: A0A089YTD6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmJ family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the guanosine in position 1516 of 16S rRNA.

216142:LT40 RS16060
gene id: 216142:LT40_RS16060
uniprot id: A0A089YZF0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Cell membrane
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

216142:LT40 RS14835
gene id: 216142:LT40_RS14835
uniprot id: A0A089YW55
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DEAD box helicase family. RhlE subfamily.
messages: Cytoplasm
messages: DEAD-box RNA helicase involved in ribosome assembly. Has RNA-dependent ATPase activity and unwinds double-stranded RNA.

216142:LT40 RS18730
gene id: 216142:LT40_RS18730
uniprot id: A0A089YSI1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Membrane

216142:LT40 RS05570
gene id: 216142:LT40_RS05570
uniprot id: A0A089YN05
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

216142:LT40 RS06610
gene id: 216142:LT40_RS06610
uniprot id: A0A089YRS9
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

216142:LT40 RS05690
gene id: 216142:LT40_RS05690
uniprot id: A0A089ZQ34
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

216142:LT40 RS06210
gene id: 216142:LT40_RS06210
uniprot id: A0A089YRM6
names: Similarity
messages: In the N-terminal section; belongs to the NADH:flavin oxidoreductase/NADH oxidase family.

216142:LT40 RS16990
gene id: 216142:LT40_RS16990
uniprot id: A0A089YRI4
names: Similarity
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
messages: Belongs to the peroxiredoxin family. Prx6 subfamily.

216142:LT40 RS04990
gene id: 216142:LT40_RS04990
uniprot id: A0A089YML0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CpoB family.
messages: Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division.
messages: Periplasm

216142:LT40 RS18695
gene id: 216142:LT40_RS18695
uniprot id: A0A089ZRG9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

216142:LT40 RS07680
gene id: 216142:LT40_RS07680
uniprot id: A0A089YUB7
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

216142:LT40 RS17155
gene id: 216142:LT40_RS17155
uniprot id: A0A089ZRB3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetyltransferase family. ArgA subfamily.
messages: Cytoplasm

216142:LT40 RS12400
gene id: 216142:LT40_RS12400
uniprot id: A0A089YUU2
names: Similarity
messages: Belongs to the UDP-glycosyltransferase family.

216142:LT40 RS19355
gene id: 216142:LT40_RS19355
uniprot id: A0A089Z172
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.
messages: Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).
messages: The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.
messages: The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1.

216142:LT40 RS12665
gene id: 216142:LT40_RS12665
uniprot id: A0A089ZQU4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transpeptidase family. MrdA subfamily.
messages: Catalyzes cross-linking of the peptidoglycan cell wall.
messages: Cell inner membrane

216142:LT40 RS09605
gene id: 216142:LT40_RS09605
uniprot id: A0A089YPX3
names: Function
names: Similarity
messages: Acts on leucine, isoleucine and valine.
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

216142:LT40 RS20360
gene id: 216142:LT40_RS20360
uniprot id: A0A089Z1N4
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

216142:LT40 RS01500
gene id: 216142:LT40_RS01500
uniprot id: A0A089YP62
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type B subfamily.
messages: Part of the 50S ribosomal subunit.

216142:LT40 RS20125
gene id: 216142:LT40_RS20125
uniprot id: A0A089YYT9
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

216142:LT40 RS03940
gene id: 216142:LT40_RS03940
uniprot id: A0A089ZPW9
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Rieske iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.
messages: Membrane
messages: The Rieske protein is a high potential 2Fe-2S protein.
messages: The main subunits of complex b-c1 are: cytochrome b, cytochrome c1 and the Rieske protein.

216142:LT40 RS11375
gene id: 216142:LT40_RS11375
uniprot id: A0A089YW83
names: Function
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.

216142:LT40 RS11700
gene id: 216142:LT40_RS11700
uniprot id: A0A089YUI1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

216142:LT40 RS11320
gene id: 216142:LT40_RS11320
uniprot id: A0A089YQV7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

216142:LT40 RS01790
gene id: 216142:LT40_RS01790
uniprot id: A0A089ZPN7
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

216142:LT40 RS13685
gene id: 216142:LT40_RS13685
uniprot id: A0A089YPT7
names: Similarity
messages: Belongs to the leucine-binding protein family.

216142:LT40 RS03560
gene id: 216142:LT40_RS03560
uniprot id: A0A089YS65
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamB family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

216142:LT40 RS19385
gene id: 216142:LT40_RS19385
uniprot id: A0A089ZRJ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0114 family.
messages: Cell membrane
messages: Membrane

216142:LT40 RS03440
gene id: 216142:LT40_RS03440
uniprot id: A0A089ZPU9
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

216142:LT40 RS14870
gene id: 216142:LT40_RS14870
uniprot id: A0A089YSN1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

216142:LT40 RS18735
gene id: 216142:LT40_RS18735
uniprot id: A0A089YUV5
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

216142:LT40 RS20380
gene id: 216142:LT40_RS20380
uniprot id: A0A089YVM6
names: Similarity
messages: Belongs to the threonine synthase family.

216142:LT40 RS18805
gene id: 216142:LT40_RS18805
uniprot id: A0A089YSK4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transpeptidase family. MrdA subfamily.
messages: Catalyzes cross-linking of the peptidoglycan cell wall.
messages: Cell inner membrane

216142:LT40 RS15060
gene id: 216142:LT40_RS15060
uniprot id: A0A089YSR2
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

216142:LT40 RS00330
gene id: 216142:LT40_RS00330
uniprot id: A0A089ZPI3
names: Similarity
messages: Belongs to the UPF0260 family.

216142:LT40 RS15695
gene id: 216142:LT40_RS15695
uniprot id: A0A089YQQ5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
messages: Single-chain monomer with multiple functions.

216142:LT40 RS04060
gene id: 216142:LT40_RS04060
uniprot id: A0A089YJR9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

216142:LT40 RS04640
gene id: 216142:LT40_RS04640
uniprot id: A0A089YQS9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

216142:LT40 RS02970
gene id: 216142:LT40_RS02970
uniprot id: A0A089YRX2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Cell membrane
messages: Membrane

216142:LT40 RS03680
gene id: 216142:LT40_RS03680
uniprot id: A0A089YLW2
names: Function
names: Similarity
messages: Belongs to the RlpA family.
messages: Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides.

216142:LT40 RS00875
gene id: 216142:LT40_RS00875
uniprot id: A0A089ZPK4
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

216142:LT40 RS12140
gene id: 216142:LT40_RS12140
uniprot id: A0A089YNW5
names: Similarity
messages: Belongs to the DNA polymerase type-B family.

216142:LT40 RS19735
gene id: 216142:LT40_RS19735
uniprot id: A0A089YYM2
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

216142:LT40 RS19405
gene id: 216142:LT40_RS19405
uniprot id: A0A089Z182
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

216142:LT40 RS10590
gene id: 216142:LT40_RS10590
uniprot id: A0A089YQF8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

216142:LT40 RS01200
gene id: 216142:LT40_RS01200
uniprot id: A0A089YI79
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Membrane

216142:LT40 RS19815
gene id: 216142:LT40_RS19815
uniprot id: A0A089YYN6
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.

216142:LT40 RS20015
gene id: 216142:LT40_RS20015
uniprot id: A0A089ZRL9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fimbrial export usher family.
messages: Cell outer membrane
messages: Membrane

216142:LT40 RS09950
gene id: 216142:LT40_RS09950
uniprot id: A0A089YTK5
names: Similarity
messages: Belongs to the hyi family.

216142:LT40 RS06040
gene id: 216142:LT40_RS06040
uniprot id: A0A089YTH7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. PdxB subfamily.
messages: Catalyzes the oxidation of erythronate-4-phosphate to 3-hydroxy-2-oxo-4-phosphonooxybutanoate.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

216142:LT40 RS20190
gene id: 216142:LT40_RS20190
uniprot id: A0A089Z1K8
names: Similarity
messages: Belongs to the UPF0246 family.

216142:LT40 RS02055
gene id: 216142:LT40_RS02055
uniprot id: A0A089YPF9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

216142:LT40 RS18915
gene id: 216142:LT40_RS18915
uniprot id: A0A089YUZ7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

216142:LT40 RS12895
gene id: 216142:LT40_RS12895
uniprot id: A0A089YV52
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

216142:LT40 RS11555
gene id: 216142:LT40_RS11555
uniprot id: A0A089YWA3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

216142:LT40 RS03205
gene id: 216142:LT40_RS03205
uniprot id: A0A089YQ29
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

216142:LT40 RS01275
gene id: 216142:LT40_RS01275
uniprot id: A0A089YI95
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmB subfamily.
messages: Methylates ribosomal protein uL3 on a specific glutamine residue.

216142:LT40 RS07470
gene id: 216142:LT40_RS07470
uniprot id: A0A089ZQA1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbsD / FucU family. RbsD subfamily.
messages: Catalyzes the interconversion of beta-pyran and beta-furan forms of D-ribose.
messages: Cytoplasm
messages: Homodecamer.

216142:LT40 RS07505
gene id: 216142:LT40_RS07505
uniprot id: A0A089YLK0
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.

216142:LT40 RS08205
gene id: 216142:LT40_RS08205
uniprot id: A0A089YUN4
names: Similarity
messages: Belongs to the proline racemase family.

216142:LT40 RS13910
gene id: 216142:LT40_RS13910
uniprot id: A0A089YYA4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MotA family.
messages: Membrane

216142:LT40 RS17100
gene id: 216142:LT40_RS17100
uniprot id: A0A089YZZ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Membrane

216142:LT40 RS01230
gene id: 216142:LT40_RS01230
uniprot id: A0A089YKH6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

216142:LT40 RS13480
gene id: 216142:LT40_RS13480
uniprot id: A0A089YVJ6
names: Similarity
messages: Belongs to the GARS family.

216142:LT40 RS13635
gene id: 216142:LT40_RS13635
uniprot id: A0A089YPT1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UreE family.
messages: Cytoplasm
messages: Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly.

216142:LT40 RS11240
gene id: 216142:LT40_RS11240
uniprot id: A0A089YQU3
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

216142:LT40 RS20530
gene id: 216142:LT40_RS20530
uniprot id: A0A089ZRN8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PEPCase type 1 family.
messages: Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.
messages: Homotetramer.

216142:LT40 RS04010
gene id: 216142:LT40_RS04010
uniprot id: A0A089YJR0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MraZ family.
messages: Forms oligomers.
messages: nucleoid

216142:LT40 RS03210
gene id: 216142:LT40_RS03210
uniprot id: A0A089YJC0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Catalyzes the dehydration of 6-phospho-D-gluconate to 2-dehydro-3-deoxy-6-phospho-D-gluconate.

216142:LT40 RS12215
gene id: 216142:LT40_RS12215
uniprot id: A0A089YWL8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

216142:LT40 RS14940
gene id: 216142:LT40_RS14940
uniprot id: A0A089YW77
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

216142:LT40 RS11290
gene id: 216142:LT40_RS11290
uniprot id: A0A089YQV2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

216142:LT40 RS12590
gene id: 216142:LT40_RS12590
uniprot id: A0A089ZQU1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
messages: Cell inner membrane
messages: Membrane

216142:LT40 RS01855
gene id: 216142:LT40_RS01855
uniprot id: A0A089YII8
names: Function
names: Similarity
messages: Belongs to the class-I DAHP synthase family.
messages: Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP).

216142:LT40 RS15275
gene id: 216142:LT40_RS15275
uniprot id: A0A089ZR41
names: Function
names: Similarity
names: Subunit
messages: Belongs to the serine/threonine dehydratase family.
messages: Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.
messages: Homotetramer.

216142:LT40 RS19455
gene id: 216142:LT40_RS19455
uniprot id: A0A089Z191
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

216142:LT40 RS16230
gene id: 216142:LT40_RS16230
uniprot id: A0A089YR63
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

216142:LT40 RS05560
gene id: 216142:LT40_RS05560
uniprot id: A0A089YRC8
names: Similarity
messages: Belongs to the PhzF family.

216142:LT40 RS16170
gene id: 216142:LT40_RS16170
uniprot id: A0A089YX01
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Membrane

216142:LT40 RS16895
gene id: 216142:LT40_RS16895
uniprot id: A0A089YZV2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Organophosphate:Pi antiporter (OPA) (TC 2.A.1.4) family.
messages: Membrane

216142:LT40 RS09565
gene id: 216142:LT40_RS09565
uniprot id: A0A089ZQH9
names: Subcellular Location Annotation
messages: Membrane

216142:LT40 RS12580
gene id: 216142:LT40_RS12580
uniprot id: A0A089YRG0
names: Function
names: Similarity
messages: Belongs to the alpha-ketoglutarate dehydrogenase family.
messages: E1 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the decarboxylation of 2-oxoglutarate, the first step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).

216142:LT40 RS06850
gene id: 216142:LT40_RS06850
uniprot id: A0A089YTW3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfur carrier protein TusA family.
messages: Cytoplasm
messages: Sulfur carrier protein which probably makes part of a sulfur-relay system.

216142:LT40 RS19245
gene id: 216142:LT40_RS19245
uniprot id: A0A089Z152
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Cell membrane
messages: Membrane

216142:LT40 RS01715
gene id: 216142:LT40_RS01715
uniprot id: A0A089ZPN4
names: Subcellular Location Annotation
messages: Membrane

216142:LT40 RS18320
gene id: 216142:LT40_RS18320
uniprot id: A0A089ZRF5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

216142:LT40 RS13020
gene id: 216142:LT40_RS13020
uniprot id: A0A089YX23
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lactate permease family.
messages: Cell inner membrane
messages: Membrane
messages: Uptake of L-lactate across the membrane. Can also transport D-lactate and glycolate.

216142:LT40 RS05900
gene id: 216142:LT40_RS05900
uniprot id: A0A089YRH8
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

216142:LT40 RS04040
gene id: 216142:LT40_RS04040
uniprot id: A0A089YM20
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane
messages: Membrane

216142:LT40 RS16135
gene id: 216142:LT40_RS16135
uniprot id: A0A089YZH1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
messages: Cytoplasm
messages: Homotrimer.
messages: In the C-terminal section; belongs to the transferase hexapeptide repeat family.
messages: In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.

216142:LT40 RS04815
gene id: 216142:LT40_RS04815
uniprot id: A0A089YSV8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LpxL/LpxM/LpxP family.
messages: Catalyzes the transfer of an acyl chain from an acyl-[acyl-carrier-protein] (ACP) to a Kdo(2)-lipid IV(A) to form a Kdo(2)-(acyl)-lipid IV(A).
messages: Cell inner membrane

216142:LT40 RS18820
gene id: 216142:LT40_RS18820
uniprot id: A0A089ZRH4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RlpA family.
messages: Cell membrane
messages: Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides.

216142:LT40 RS02155
gene id: 216142:LT40_RS02155
uniprot id: A0A089YL04
names: Similarity
messages: Belongs to the transglycosylase Slt family.

216142:LT40 RS07240
gene id: 216142:LT40_RS07240
uniprot id: A0A089ZQ92
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the diacylglycerol/lipid kinase family. YegS lipid kinase subfamily.
messages: Binds 1 Mg(2+) ion per subunit. Ca(2+) may be able to substitute.
messages: Cytoplasm
messages: Probably phosphorylates lipids; the in vivo substrate is unknown.

216142:LT40 RS00360
gene id: 216142:LT40_RS00360
uniprot id: A0A089YNP1
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.

216142:LT40 RS04770
gene id: 216142:LT40_RS04770
uniprot id: A0A089ZQ01
names: Function
names: Similarity
names: Subunit
messages: Belongs to the P-Pant transferase superfamily. EntD family.
messages: EntB, EntD, EntE, and EntF form a multienzyme complex called enterobactin synthase.
messages: Involved in the biosynthesis of the siderophore enterobactin (enterochelin), which is a macrocyclic trimeric lactone of N-(2,3-dihydroxybenzoyl)-serine. The serine trilactone serves as a scaffolding for the three catechol functionalities that provide hexadentate coordination for the tightly ligated iron(2+) atoms. Plays an essential role in the assembly of the enterobactin by catalyzing the transfer of the 4'-phosphopantetheine (Ppant) moiety from coenzyme A to the apo-domains of both EntB (ArCP domain) and EntF (PCP domain) to yield their holo-forms which make them competent for the activation of 2,3-dihydroxybenzoate (DHB) and L-serine, respectively.

216142:LT40 RS08945
gene id: 216142:LT40_RS08945
uniprot id: A0A089YUX5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

216142:LT40 RS18315
gene id: 216142:LT40_RS18315
uniprot id: A0A089Z0K8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

216142:LT40 RS18305
gene id: 216142:LT40_RS18305
uniprot id: A0A089YS68
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

216142:LT40 RS12250
gene id: 216142:LT40_RS12250
uniprot id: A0A089YUR8
names: Subcellular Location Annotation
messages: Membrane

216142:LT40 RS05660
gene id: 216142:LT40_RS05660
uniprot id: A0A089ZQ33
names: Similarity
messages: Belongs to the ArsC family.

216142:LT40 RS10135
gene id: 216142:LT40_RS10135
uniprot id: A0A089ZQK0
names: Similarity
messages: Belongs to the UxaA family.

216142:LT40 RS16780
gene id: 216142:LT40_RS16780
uniprot id: A0A089YRF2
names: Function
names: Similarity
messages: Belongs to the uroporphyrinogen-III synthase family.
messages: Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.

216142:LT40 RS19580
gene id: 216142:LT40_RS19580
uniprot id: A0A089Z1A7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

216142:LT40 RS11795
gene id: 216142:LT40_RS11795
uniprot id: A0A089YR26
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

216142:LT40 RS10190
gene id: 216142:LT40_RS10190
uniprot id: A0A089ZQK2
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily.

216142:LT40 RS15825
gene id: 216142:LT40_RS15825
uniprot id: A0A089YQT8
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

216142:LT40 RS14665
gene id: 216142:LT40_RS14665
uniprot id: A0A089YYP1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoH subfamily.
messages: Cytoplasm
messages: Interacts with the RNA polymerase core enzyme.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes.

216142:LT40 RS18800
gene id: 216142:LT40_RS18800
uniprot id: A0A089YY65
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

216142:LT40 RS12575
gene id: 216142:LT40_RS12575
uniprot id: A0A089YP43
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 1 lipoyl cofactor covalently.
messages: E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).

216142:LT40 RS15485
gene id: 216142:LT40_RS15485
uniprot id: A0A089YQK8
names: Subcellular Location Annotation
messages: Membrane

216142:LT40 RS19885
gene id: 216142:LT40_RS19885
uniprot id: A0A089ZRL4
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. SDR39U1 subfamily.

216142:LT40 RS04530
gene id: 216142:LT40_RS04530
uniprot id: A0A089YSP2
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

216142:LT40 RS02330
gene id: 216142:LT40_RS02330
uniprot id: A0A089YRH4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
messages: Bacterial flagellum basal body
messages: Belongs to the FlgH family.
messages: Cell outer membrane
messages: Membrane
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod.

216142:LT40 RS16490
gene id: 216142:LT40_RS16490
uniprot id: A0A089YZM2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

216142:LT40 RS12950
gene id: 216142:LT40_RS12950
uniprot id: A0A089ZQV4
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

216142:LT40 RS20700
gene id: 216142:LT40_RS20700
uniprot id: A0A089YVU6
names: Cofactor
names: Function
messages: Binds 2 [4Fe-4S] clusters.
messages: Component of a complex that catalyzes the oxidation of glycolate to glyoxylate.

216142:LT40 RS02605
gene id: 216142:LT40_RS02605
uniprot id: A0A089YRN8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbE subfamily.
messages: Cell inner membrane

216142:LT40 RS01065
gene id: 216142:LT40_RS01065
uniprot id: A0A089YKF5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane

216142:LT40 RS13820
gene id: 216142:LT40_RS13820
uniprot id: A0A089YPV1
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

216142:LT40 RS17330
gene id: 216142:LT40_RS17330
uniprot id: A0A089Z031
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family.
messages: Binds 1 Mg(2+) ion per subunit. Can also utilize other divalent metal cations, such as Ca(2+), Mn(2+) and Co(2+).
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
messages: Homodimer.

216142:LT40 RS00820
gene id: 216142:LT40_RS00820
uniprot id: A0A089YQQ6
names: Subcellular Location Annotation
messages: Membrane

216142:LT40 RS13265
gene id: 216142:LT40_RS13265
uniprot id: A0A089YRT2
names: Subcellular Location Annotation
messages: Membrane

216142:LT40 RS13545
gene id: 216142:LT40_RS13545
uniprot id: A0A089YY50
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

216142:LT40 RS12025
gene id: 216142:LT40_RS12025
uniprot id: A0A089ZQS0
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

216142:LT40 RS10340
gene id: 216142:LT40_RS10340
uniprot id: A0A089YVP4
names: Similarity
messages: Belongs to the TPP enzyme family.

216142:LT40 RS13935
gene id: 216142:LT40_RS13935
uniprot id: A0A089YS86
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

216142:LT40 RS18345
gene id: 216142:LT40_RS18345
uniprot id: A0A089ZRF6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

216142:LT40 RS16520
gene id: 216142:LT40_RS16520
uniprot id: A0A089ZR88
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm

216142:LT40 RS18405
gene id: 216142:LT40_RS18405
uniprot id: A0A089YS93
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

216142:LT40 RS16540
gene id: 216142:LT40_RS16540
uniprot id: A0A089YZN3
names: Similarity
messages: Belongs to the UPF0758 family.

216142:LT40 RS14475
gene id: 216142:LT40_RS14475
uniprot id: A0A089YSH2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S-adenosyl-L-methionine to the 2'-OH of the wobble nucleotide.

216142:LT40 RS07570
gene id: 216142:LT40_RS07570
uniprot id: A0A089YNX2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

216142:LT40 RS05275
gene id: 216142:LT40_RS05275
uniprot id: A0A089YKH0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

216142:LT40 RS17340
gene id: 216142:LT40_RS17340
uniprot id: A0A089YXH7
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

216142:LT40 RS17625
gene id: 216142:LT40_RS17625
uniprot id: A0A089YXL4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. NhaP2 subfamily.
messages: Cell membrane
messages: K(+)/H(+) antiporter that extrudes potassium in exchange for external protons and maintains the internal concentration of potassium under toxic levels.

216142:LT40 RS14340
gene id: 216142:LT40_RS14340
uniprot id: A0A089YQ26
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

216142:LT40 RS12730
gene id: 216142:LT40_RS12730
uniprot id: A0A089YRI6
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the MsrP family.
messages: Binds 1 Mo-molybdopterin (Mo-MPT) cofactor per subunit.
messages: Heterodimer of a catalytic subunit (MsrP) and a heme-binding subunit (MsrQ).
messages: Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide.
messages: Predicted to be exported by the Tat system. The position of the signal peptide cleavage has not been experimentally proven.

216142:LT40 RS09600
gene id: 216142:LT40_RS09600
uniprot id: A0A089YMM1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-C family. DnaE2 subfamily.
messages: Cytoplasm
messages: DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase.

216142:LT40 RS06560
gene id: 216142:LT40_RS06560
uniprot id: A0A089YTR7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

216142:LT40 RS18490
gene id: 216142:LT40_RS18490
uniprot id: A0A089Z0Q3
names: Function
names: Similarity
messages: Belongs to the bacterioferritin family.
messages: Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex.

216142:LT40 RS12275
gene id: 216142:LT40_RS12275
uniprot id: A0A089YUS1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell outer membrane

216142:LT40 RS08930
gene id: 216142:LT40_RS08930
uniprot id: A0A089YT31
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

216142:LT40 RS04785
gene id: 216142:LT40_RS04785
uniprot id: A0A089YMH1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

216142:LT40 RS20210
gene id: 216142:LT40_RS20210
uniprot id: A0A089YVI9
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

216142:LT40 RS18295
gene id: 216142:LT40_RS18295
uniprot id: A0A089ZRF4
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

216142:LT40 RS06280
gene id: 216142:LT40_RS06280
uniprot id: A0A089YTL8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

216142:LT40 RS15680
gene id: 216142:LT40_RS15680
uniprot id: A0A089YZ64
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbA subfamily.
messages: Periplasm

216142:LT40 RS12935
gene id: 216142:LT40_RS12935
uniprot id: A0A089YPA5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.
messages: Cytoplasm
messages: Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.

216142:LT40 RS16690
gene id: 216142:LT40_RS16690
uniprot id: A0A089YZR2
names: Similarity
messages: Belongs to the P(II) protein family.

216142:LT40 RS14410
gene id: 216142:LT40_RS14410
uniprot id: A0A089ZR09
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the calycin superfamily. Lipocalin family.
messages: Cell outer membrane
messages: Homodimer.
messages: Involved in the storage or transport of lipids necessary for membrane maintenance under stressful conditions. Displays a binding preference for lysophospholipids.

216142:LT40 RS15180
gene id: 216142:LT40_RS15180
uniprot id: A0A089YWA9
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

216142:LT40 RS11520
gene id: 216142:LT40_RS11520
uniprot id: A0A089YNL5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phospholipase D family. Cardiolipin synthase subfamily. ClsB sub-subfamily.
messages: Catalyzes the phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol.
messages: Cell membrane

216142:LT40 RS13550
gene id: 216142:LT40_RS13550
uniprot id: A0A089ZQX6
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

216142:LT40 RS01940
gene id: 216142:LT40_RS01940
uniprot id: A0A089YR90
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
messages: Cell membrane
messages: Monomer.

216142:LT40 RS20435
gene id: 216142:LT40_RS20435
uniprot id: A0A089YTB1
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

216142:LT40 RS16565
gene id: 216142:LT40_RS16565
uniprot id: A0A089YZN8
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

216142:LT40 RS16340
gene id: 216142:LT40_RS16340
uniprot id: A0A089YZJ8
names: Similarity
messages: Belongs to the glucose-6-phosphate 1-epimerase family.

216142:LT40 RS13940
gene id: 216142:LT40_RS13940
uniprot id: A0A089YYA9
names: Similarity
messages: Belongs to the Smp family.

216142:LT40 RS18480
gene id: 216142:LT40_RS18480
uniprot id: A0A089YSB2
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

216142:LT40 RS00145
gene id: 216142:LT40_RS00145
uniprot id: A0A089YK25
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

216142:LT40 RS07820
gene id: 216142:LT40_RS07820
uniprot id: A0A089YP26
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.
messages: Membrane

216142:LT40 RS16900
gene id: 216142:LT40_RS16900
uniprot id: A0A089ZRA3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliL family.
messages: Cell inner membrane
messages: Controls the rotational direction of flagella during chemotaxis.
messages: Membrane

216142:LT40 RS12990
gene id: 216142:LT40_RS12990
uniprot id: A0A089YRP0
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Fur family.
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.

216142:LT40 RS13300
gene id: 216142:LT40_RS13300
uniprot id: A0A089ZQW6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenine deaminase type 2 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism.

216142:LT40 RS07100
gene id: 216142:LT40_RS07100
uniprot id: A0A089ZQ87
names: Similarity
messages: Belongs to the PrpD family.

216142:LT40 RS10615
gene id: 216142:LT40_RS10615
uniprot id: A0A089YQG6
names: Function
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. S-2-haloalkanoic acid dehalogenase family.
messages: Catalyzes the hydrolytic dehalogenation of small (S)-2-haloalkanoic acids to yield the corresponding (R)-2-hydroxyalkanoic acids.

216142:LT40 RS12255
gene id: 216142:LT40_RS12255
uniprot id: A0A089YNY0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EamA transporter family.
messages: Membrane

216142:LT40 RS01135
gene id: 216142:LT40_RS01135
uniprot id: A0A089YI69
names: Similarity
messages: Belongs to the aspartokinase family.

216142:LT40 RS14590
gene id: 216142:LT40_RS14590
uniprot id: A0A089ZR16
names: Similarity
messages: Belongs to the peptidase C40 family.

216142:LT40 RS06645
gene id: 216142:LT40_RS06645
uniprot id: A0A089YNG0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

216142:LT40 RS09940
gene id: 216142:LT40_RS09940
uniprot id: A0A089YVF5
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.

216142:LT40 RS17005
gene id: 216142:LT40_RS17005
uniprot id: A0A089ZRA7
names: Function
names: Similarity
messages: Belongs to the SsuD family.
messages: Catalyzes the desulfonation of aliphatic sulfonates.

216142:LT40 RS00970
gene id: 216142:LT40_RS00970
uniprot id: A0A089YKE4
names: Similarity
messages: Belongs to the TrpF family.

216142:LT40 RS06230
gene id: 216142:LT40_RS06230
uniprot id: A0A089ZQ55
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

216142:LT40 RS17260
gene id: 216142:LT40_RS17260
uniprot id: A0A089ZRB7
names: Subcellular Location Annotation
messages: Membrane

216142:LT40 RS12930
gene id: 216142:LT40_RS12930
uniprot id: A0A089YV58
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

216142:LT40 RS02345
gene id: 216142:LT40_RS02345
uniprot id: A0A089YIV0
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the flagella basal body rod proteins family.
messages: Secreted

216142:LT40 RS00665
gene id: 216142:LT40_RS00665
uniprot id: A0A089ZPJ6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase E/G family. RNase E subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per homotetramer.
messages: Cell inner membrane
messages: Component of the RNA degradosome, which is a multiprotein complex involved in RNA processing and mRNA degradation. Within the RNA degradosome, RNase E assembles into a homotetramer formed by a dimer of dimers.
messages: Cytoplasm
messages: Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs.

216142:LT40 RS03620
gene id: 216142:LT40_RS03620
uniprot id: A0A089YQ90
names: Similarity
messages: Belongs to the outer membrane porin (Opr) (TC 1.B.25) family.

216142:LT40 RS17615
gene id: 216142:LT40_RS17615
uniprot id: A0A089Z088
names: Function
names: Similarity
messages: Belongs to the SELO family.
messages: Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr or Tyr residues of target proteins (AMPylation).

216142:LT40 RS10840
gene id: 216142:LT40_RS10840
uniprot id: A0A089YQN7
names: Subcellular Location Annotation
messages: Cell inner membrane

216142:LT40 RS17010
gene id: 216142:LT40_RS17010
uniprot id: A0A089YXC9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

216142:LT40 RS18935
gene id: 216142:LT40_RS18935
uniprot id: A0A089YSM1
names: Function
names: Similarity
messages: Belongs to the AMP nucleosidase family.
messages: Catalyzes the hydrolysis of the N-glycosidic bond of AMP to form adenine and ribose 5-phosphate. Involved in regulation of AMP concentrations.

216142:LT40 RS04515
gene id: 216142:LT40_RS04515
uniprot id: A0A089YK05
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

216142:LT40 RS13195
gene id: 216142:LT40_RS13195
uniprot id: A0A089YX60
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit contributes ATPase, 3'-5' helicase, exonuclease activity and loads RecA onto ssDNA.
messages: Belongs to the helicase family. UvrD subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotrimer of RecB, RecC and RecD. All subunits contribute to DNA-binding. Interacts with RecA.
messages: The C-terminal domain has nuclease activity and interacts with RecD. It interacts with RecA, facilitating its loading onto ssDNA.
messages: The N-terminal DNA-binding domain is a ssDNA-dependent ATPase and has ATP-dependent 3'-5' helicase function. This domain interacts with RecC.

216142:LT40 RS14075
gene id: 216142:LT40_RS14075
uniprot id: A0A089ZQZ6
names: Similarity
messages: Belongs to the shaker potassium channel beta subunit family.

216142:LT40 RS19790
gene id: 216142:LT40_RS19790
uniprot id: A0A089YT11
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

216142:LT40 RS01960
gene id: 216142:LT40_RS01960
uniprot id: A0A089YKW0
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

216142:LT40 RS04350
gene id: 216142:LT40_RS04350
uniprot id: A0A089YSK9
names: Subcellular Location Annotation
messages: Membrane

216142:LT40 RS19310
gene id: 216142:LT40_RS19310
uniprot id: A0A089ZRJ3
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

216142:LT40 RS03315
gene id: 216142:LT40_RS03315
uniprot id: A0A089YLR1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 2 family.
messages: Cell membrane
messages: Membrane

216142:LT40 RS02795
gene id: 216142:LT40_RS02795
uniprot id: A0A089ZPS5
names: Similarity
messages: Belongs to the peptidase S11 family.

216142:LT40 RS04590
gene id: 216142:LT40_RS04590
uniprot id: A0A089YQR6
names: Function
names: Similarity
messages: An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH and other flavinylated proteins as well.
messages: Belongs to the SdhE FAD assembly factor family.

216142:LT40 RS08550
gene id: 216142:LT40_RS08550
uniprot id: A0A089YSX0
names: Subcellular Location Annotation
messages: Membrane

216142:LT40 RS02985
gene id: 216142:LT40_RS02985
uniprot id: A0A089YJ92
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

216142:LT40 RS05040
gene id: 216142:LT40_RS05040
uniprot id: A0A089YR13
names: Similarity
messages: Belongs to the glutathione peroxidase family.

216142:LT40 RS20615
gene id: 216142:LT40_RS20615
uniprot id: A0A089YTE7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the periplasmic pilus chaperone family.
messages: Periplasm

216142:LT40 RS17590
gene id: 216142:LT40_RS17590
uniprot id: A0A089Z083
names: Subcellular Location Annotation
messages: Membrane

216142:LT40 RS10870
gene id: 216142:LT40_RS10870
uniprot id: A0A089YQP3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Mediates global changes in gene expression, shifting from rapid growth to stress survival by linking envelope stress, the stringent response and the catabolite repression systems. Usually binds in the 5'-UTR; binding at or near the Shine-Dalgarno sequence prevents ribosome-binding, repressing translation, binding elsewhere in the 5'-UTR can activate translation and/or stabilize the mRNA. Its function is antagonized by small RNA(s).
messages: Belongs to the CsrA/RsmA family.
messages: Cytoplasm
messages: Homodimer; the beta-strands of each monomer intercalate to form a hydrophobic core, while the alpha-helices form wings that extend away from the core.

216142:LT40 RS19920
gene id: 216142:LT40_RS19920
uniprot id: A0A089YT33
names: Similarity
messages: Belongs to the MQO family.

216142:LT40 RS06165
gene id: 216142:LT40_RS06165
uniprot id: A0A089YTJ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

216142:LT40 RS10810
gene id: 216142:LT40_RS10810
uniprot id: A0A089YQN2
names: Cofactor
messages: Binds 1 Fe(2+) ion per subunit.

216142:LT40 RS06705
gene id: 216142:LT40_RS06705
uniprot id: A0A089ZQ72
names: Function
names: Similarity
messages: Belongs to the CobB/CobQ family. CobQ subfamily.
messages: Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation.

216142:LT40 RS14375
gene id: 216142:LT40_RS14375
uniprot id: A0A089YYJ0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

216142:LT40 RS11500
gene id: 216142:LT40_RS11500
uniprot id: A0A089YQY5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

216142:LT40 RS13720
gene id: 216142:LT40_RS13720
uniprot id: A0A089YY75
names: Cofactor
names: Similarity
messages: Belongs to the UPF0313 family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

216142:LT40 RS04850
gene id: 216142:LT40_RS04850
uniprot id: A0A089YQX6
names: Function
names: Similarity
messages: Belongs to the LpxK family.
messages: Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).

216142:LT40 RS12785
gene id: 216142:LT40_RS12785
uniprot id: A0A089YWW9
names: Similarity
messages: Belongs to the SfsA family.

216142:LT40 RS14210
gene id: 216142:LT40_RS14210
uniprot id: A0A089YVV1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Monomer.

216142:LT40 RS10780
gene id: 216142:LT40_RS10780
uniprot id: A0A089YNB9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DsrE/TusD family.
messages: Cytoplasm

216142:LT40 RS14435
gene id: 216142:LT40_RS14435
uniprot id: A0A089ZR10
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

216142:LT40 RS16130
gene id: 216142:LT40_RS16130
uniprot id: A0A089YTF4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

216142:LT40 RS18840
gene id: 216142:LT40_RS18840
uniprot id: A0A089Z0Y4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

216142:LT40 RS20595
gene id: 216142:LT40_RS20595
uniprot id: A0A089YVS2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M20A family. DapE subfamily.
messages: Binds 2 Zn(2+) or Co(2+) ions per subunit.
messages: Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls.
messages: Homodimer.

216142:LT40 RS11415
gene id: 216142:LT40_RS11415
uniprot id: A0A089YNJ8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 2 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 13 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

216142:LT40 RS03815
gene id: 216142:LT40_RS03815
uniprot id: A0A089ZPW4
names: Similarity
messages: Belongs to the SIS family. GutQ/KpsF subfamily.

216142:LT40 RS14440
gene id: 216142:LT40_RS14440
uniprot id: A0A089YVY4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThiI family.
messages: Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

216142:LT40 RS11605
gene id: 216142:LT40_RS11605
uniprot id: A0A089YR00
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

216142:LT40 RS18380
gene id: 216142:LT40_RS18380
uniprot id: A0A089YS87
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

216142:LT40 RS12960
gene id: 216142:LT40_RS12960
uniprot id: A0A089YPB2
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

216142:LT40 RS05310
gene id: 216142:LT40_RS05310
uniprot id: A0A089ZQ20
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

216142:LT40 RS17210
gene id: 216142:LT40_RS17210
uniprot id: A0A089ZRB5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Cytoplasm
messages: Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

216142:LT40 RS12260
gene id: 216142:LT40_RS12260
uniprot id: A0A089YR93
names: Similarity
messages: Belongs to the UPF0053 family.

216142:LT40 RS10835
gene id: 216142:LT40_RS10835
uniprot id: A0A089YNC8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

216142:LT40 RS16205
gene id: 216142:LT40_RS16205
uniprot id: A0A089YR58
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily.

216142:LT40 RS04505
gene id: 216142:LT40_RS04505
uniprot id: A0A089ZPZ1
names: Subcellular Location Annotation
messages: Membrane

216142:LT40 RS19410
gene id: 216142:LT40_RS19410
uniprot id: A0A089ZRJ7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

216142:LT40 RS19680
gene id: 216142:LT40_RS19680
uniprot id: A0A089YYL3
names: Function
names: Similarity
messages: Belongs to the NadC/ModD family.
messages: Involved in the catabolism of quinolinic acid (QA).

216142:LT40 RS10410
gene id: 216142:LT40_RS10410
uniprot id: A0A089YTU5
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

216142:LT40 RS19725
gene id: 216142:LT40_RS19725
uniprot id: A0A089Z1D2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm

216142:LT40 RS20045
gene id: 216142:LT40_RS20045
uniprot id: A0A089ZRM0
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

216142:LT40 RS06155
gene id: 216142:LT40_RS06155
uniprot id: A0A089YKW7
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

216142:LT40 RS11305
gene id: 216142:LT40_RS11305
uniprot id: A0A089ZQP3
names: Subcellular Location Annotation
messages: Cytoplasm

216142:LT40 RS13725
gene id: 216142:LT40_RS13725
uniprot id: A0A089ZQY3
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins.

216142:LT40 RS07355
gene id: 216142:LT40_RS07355
uniprot id: A0A089YNS7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

216142:LT40 RS07260
gene id: 216142:LT40_RS07260
uniprot id: A0A089YU31
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCF family. Uup subfamily.
messages: Cytoplasm
messages: Probably plays a role in ribosome assembly or function. May be involved in resolution of branched DNA intermediates that result from template switching in postreplication gaps. Binds DNA and has ATPase activity.

216142:LT40 RS03730
gene id: 216142:LT40_RS03730
uniprot id: A0A089YLW8
names: Similarity
messages: Belongs to the peptidase U62 family.

216142:LT40 RS00690
gene id: 216142:LT40_RS00690
uniprot id: A0A089YQN1
names: Function
names: Similarity
messages: Belongs to the DUF177 domain family.
messages: Plays a role in synthesis, processing and/or stability of 23S rRNA.

216142:LT40 RS12070
gene id: 216142:LT40_RS12070
uniprot id: A0A089YR64
names: Similarity
messages: Belongs to the MlaA family.

216142:LT40 RS01225
gene id: 216142:LT40_RS01225
uniprot id: A0A089YI84
names: Subcellular Location Annotation
messages: Membrane

216142:LT40 RS05270
gene id: 216142:LT40_RS05270
uniprot id: A0A089YR61
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

216142:LT40 RS06555
gene id: 216142:LT40_RS06555
uniprot id: A0A089YNE5
names: Similarity
messages: Belongs to the peptidase M1 family.

216142:LT40 RS05235
gene id: 216142:LT40_RS05235
uniprot id: A0A089ZQ18
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane

216142:LT40 RS20540
gene id: 216142:LT40_RS20540
uniprot id: A0A089YTD1
names: Similarity
messages: Belongs to the KAE1 / TsaD family. TsaB subfamily.

216142:LT40 RS01935
gene id: 216142:LT40_RS01935
uniprot id: A0A089YKV5
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

216142:LT40 RS11865
gene id: 216142:LT40_RS11865
uniprot id: A0A089ZQR4
names: Similarity
messages: Belongs to the NtaA/SnaA/DszA monooxygenase family.

216142:LT40 RS11025
gene id: 216142:LT40_RS11025
uniprot id: A0A089YU79
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

216142:LT40 RS10385
gene id: 216142:LT40_RS10385
uniprot id: A0A089YTU0
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

216142:LT40 RS18690
gene id: 216142:LT40_RS18690
uniprot id: A0A089Z0U3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

216142:LT40 RS03695
gene id: 216142:LT40_RS03695
uniprot id: A0A089YQA4
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

216142:LT40 RS01745
gene id: 216142:LT40_RS01745
uniprot id: A0A089YP99
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KdpA family.
messages: Cell membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds the extracellular potassium ions and delivers the ions to the membrane domain of KdpB through an intramembrane tunnel.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

216142:LT40 RS10220
gene id: 216142:LT40_RS10220
uniprot id: A0A089ZQK3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nicotinamide ribonucleoside (NR) uptake permease (TC 4.B.1) family.
messages: Membrane
messages: Required for nicotinamide riboside transport across the inner membrane.

216142:LT40 RS13950
gene id: 216142:LT40_RS13950
uniprot id: A0A089YVR3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 1 subfamily.
messages: Cell membrane
messages: Heterotetramer composed of ParC and ParE.
messages: Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.

216142:LT40 RS02730
gene id: 216142:LT40_RS02730
uniprot id: A0A089YLG8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

216142:LT40 RS07530
gene id: 216142:LT40_RS07530
uniprot id: A0A089YLK7
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

216142:LT40 RS18340
gene id: 216142:LT40_RS18340
uniprot id: A0A089Z0L5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

216142:LT40 RS11390
gene id: 216142:LT40_RS11390
uniprot id: A0A089YNJ5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 23 kDa subunit family.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell membrane
messages: NDH-1 is composed of 13 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

216142:LT40 RS11620
gene id: 216142:LT40_RS11620
uniprot id: A0A089YUG9
names: Similarity
messages: Belongs to the Nudix hydrolase family.

216142:LT40 RS13065
gene id: 216142:LT40_RS13065
uniprot id: A0A089YV89
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

216142:LT40 RS01950
gene id: 216142:LT40_RS01950
uniprot id: A0A089YPD8
names: Similarity
messages: Belongs to the peptidase S13 family.

216142:LT40 RS18595
gene id: 216142:LT40_RS18595
uniprot id: A0A089ZRG6
names: Caution
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the thiamine-monophosphate kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate.

216142:LT40 RS00715
gene id: 216142:LT40_RS00715
uniprot id: A0A089YQN6
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

216142:LT40 RS02410
gene id: 216142:LT40_RS02410
uniprot id: A0A089ZPR0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliG family.
messages: Cell inner membrane
messages: FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
messages: Membrane

216142:LT40 RS16760
gene id: 216142:LT40_RS16760
uniprot id: A0A089YTS0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm
messages: In the N-terminal section; belongs to the lyase 1 family. Argininosuccinate lyase subfamily.

216142:LT40 RS08360
gene id: 216142:LT40_RS08360
uniprot id: A0A089YUQ4
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Member of a two-component regulatory system.

216142:LT40 RS01900
gene id: 216142:LT40_RS01900
uniprot id: A0A089YPC9
names: Function
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.
messages: Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate.

216142:LT40 RS09720
gene id: 216142:LT40_RS09720
uniprot id: A0A089YVC0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily.
messages: Catalyzes the hydrolysis of 5-hydroxyisourate (HIU) to 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU).
messages: Homotetramer.

216142:LT40 RS03075
gene id: 216142:LT40_RS03075
uniprot id: A0A089ZPT5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

216142:LT40 RS13600
gene id: 216142:LT40_RS13600
uniprot id: A0A089ZQX8
names: Similarity
messages: Belongs to the heat shock protein 70 family.

216142:LT40 RS18505
gene id: 216142:LT40_RS18505
uniprot id: A0A089YSB8
names: Caution
names: Function
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.

216142:LT40 RS16925
gene id: 216142:LT40_RS16925
uniprot id: A0A089ZRA4
names: Similarity
messages: Belongs to the UPF0149 family.

216142:LT40 RS03240
gene id: 216142:LT40_RS03240
uniprot id: A0A089YLP7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

216142:LT40 RS16670
gene id: 216142:LT40_RS16670
uniprot id: A0A089ZR94
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

216142:LT40 RS05595
gene id: 216142:LT40_RS05595
uniprot id: A0A089YN10
names: Similarity
messages: Belongs to the Lgt family.

216142:LT40 RS20325
gene id: 216142:LT40_RS20325
uniprot id: A0A089YT95
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Homodimer.
messages: Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate.

216142:LT40 RS01690
gene id: 216142:LT40_RS01690
uniprot id: A0A089ZPN3
names: Similarity
messages: Belongs to the bacterial PQQ dehydrogenase family.

216142:LT40 RS05585
gene id: 216142:LT40_RS05585
uniprot id: A0A089YRD0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.

216142:LT40 RS17515
gene id: 216142:LT40_RS17515
uniprot id: A0A089ZRC7
names: Similarity
messages: In the N-terminal section; belongs to the NADH:flavin oxidoreductase/NADH oxidase family.

216142:LT40 RS16800
gene id: 216142:LT40_RS16800
uniprot id: A0A089YX99
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

216142:LT40 RS05635
gene id: 216142:LT40_RS05635
uniprot id: A0A089YRE0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

216142:LT40 RS18175
gene id: 216142:LT40_RS18175
uniprot id: A0A089YXV1
names: Similarity
messages: Belongs to the TrpC family.

216142:LT40 RS19895
gene id: 216142:LT40_RS19895
uniprot id: A0A089YT28
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

216142:LT40 RS08725
gene id: 216142:LT40_RS08725
uniprot id: A0A089YUU5
names: Similarity
messages: Belongs to the peptidase S14 family.

216142:LT40 RS06570
gene id: 216142:LT40_RS06570
uniprot id: A0A089YRS6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RdgC family.
messages: May be involved in recombination.
messages: nucleoid

216142:LT40 RS12355
gene id: 216142:LT40_RS12355
uniprot id: A0A089YNZ9
names: Function
names: Similarity
messages: Belongs to the ribose 1,5-bisphosphokinase family.
messages: Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP).
messages: In the C-terminal section; belongs to the thymidine/pyrimidine-nucleoside phosphorylase family. Type 2 subfamily.
messages: In the N-terminal section; belongs to the ribose 1,5-bisphosphokinase family.

216142:LT40 RS16125
gene id: 216142:LT40_RS16125
uniprot id: A0A089YR45
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family. T3SS ATPase subfamily.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

216142:LT40 RS14640
gene id: 216142:LT40_RS14640
uniprot id: A0A089YYN7
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

216142:LT40 RS00130
gene id: 216142:LT40_RS00130
uniprot id: A0A089ZPH6
names: Similarity
messages: Belongs to the SIP oxidoreductase family.

216142:LT40 RS05245
gene id: 216142:LT40_RS05245
uniprot id: A0A089YKG5
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

216142:LT40 RS09180
gene id: 216142:LT40_RS09180
uniprot id: A0A089YT69
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
messages: Cell inner membrane

216142:LT40 RS04355
gene id: 216142:LT40_RS04355
uniprot id: A0A089ZPY5
names: Similarity
messages: Belongs to the class-II fumarase/aspartase family.

216142:LT40 RS19805
gene id: 216142:LT40_RS19805
uniprot id: A0A089ZRL1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

216142:LT40 RS18210
gene id: 216142:LT40_RS18210
uniprot id: A0A089YUJ0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HemJ family.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.
messages: Catalyzes the oxidation of protoporphyrinogen IX to protoporphyrin IX.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

216142:LT40 RS14420
gene id: 216142:LT40_RS14420
uniprot id: A0A089YQ39
names: Function
names: Similarity
messages: Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis.
messages: Belongs to the glycogen phosphorylase family.
messages: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.

216142:LT40 RS05700
gene id: 216142:LT40_RS05700
uniprot id: A0A089YKQ0
names: Subcellular Location Annotation
messages: Membrane

216142:LT40 RS12145
gene id: 216142:LT40_RS12145
uniprot id: A0A089YR74
names: Similarity
messages: Belongs to the type IA topoisomerase family.

216142:LT40 RS07535
gene id: 216142:LT40_RS07535
uniprot id: A0A089YNW9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial histone-like protein family.
messages: Heterodimer of an alpha and a beta chain.
messages: This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.

216142:LT40 RS13470
gene id: 216142:LT40_RS13470
uniprot id: A0A089YY37
names: Similarity
messages: Belongs to the transcriptional regulatory Fis family.

216142:LT40 RS02610
gene id: 216142:LT40_RS02610
uniprot id: A0A089ZPR8
names: Function
names: Similarity
messages: Belongs to the CcmH/CycL/Ccl2/NrfF family.
messages: Possible subunit of a heme lyase.

216142:LT40 RS03165
gene id: 216142:LT40_RS03165
uniprot id: A0A089YLN4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

216142:LT40 RS20000
gene id: 216142:LT40_RS20000
uniprot id: A0A089YVF3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Homohexamer.
messages: In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.
messages: In the N-terminal section; belongs to the CobB/CobQ family.
messages: Involved in acetate metabolism.
messages: The N-terminal region seems to be important for proper quaternary structure. The C-terminal region contains the substrate-binding site.

216142:LT40 RS11200
gene id: 216142:LT40_RS11200
uniprot id: A0A089ZQN9
names: Similarity
messages: Belongs to the citrate synthase family.

216142:LT40 RS00720
gene id: 216142:LT40_RS00720
uniprot id: A0A089ZPJ8
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

216142:LT40 RS16880
gene id: 216142:LT40_RS16880
uniprot id: A0A089YXB1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UbiD family.
messages: Binds 1 prenylated FMN (prenyl-FMN) per subunit.
messages: Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis.
messages: Cell membrane
messages: Homohexamer.

216142:LT40 RS19900
gene id: 216142:LT40_RS19900
uniprot id: A0A089YVD9
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
messages: Allosterically activated by GTP.
messages: Belongs to the UPRTase family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.
messages: Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.

216142:LT40 RS18410
gene id: 216142:LT40_RS18410
uniprot id: A0A089YUM0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

216142:LT40 RS03805
gene id: 216142:LT40_RS03805
uniprot id: A0A089YLY1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptC family.
messages: Cell inner membrane
messages: Component of the lipopolysaccharide transport and assembly complex. Interacts with LptA and the LptBFG transporter complex.
messages: Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. Facilitates the transfer of LPS from the inner membrane to the periplasmic protein LptA. Could be a docking site for LptA.

216142:LT40 RS00445
gene id: 216142:LT40_RS00445
uniprot id: A0A089YHW0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

216142:LT40 RS09890
gene id: 216142:LT40_RS09890
uniprot id: A0A089YVE8
names: Similarity
messages: Belongs to the RutC family.

216142:LT40 RS14860
gene id: 216142:LT40_RS14860
uniprot id: A0A089YW61
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

216142:LT40 RS13895
gene id: 216142:LT40_RS13895
uniprot id: A0A089YVQ4
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: May also have succinyldiaminopimelate aminotransferase activity, thus carrying out the corresponding step in lysine biosynthesis.

216142:LT40 RS11280
gene id: 216142:LT40_RS11280
uniprot id: A0A089YUC0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L/F-transferase family.
messages: Cytoplasm
messages: Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.

216142:LT40 RS02360
gene id: 216142:LT40_RS02360
uniprot id: A0A089ZPQ8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

216142:LT40 RS03405
gene id: 216142:LT40_RS03405
uniprot id: A0A089YS37
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YajC family.
messages: Cell inner membrane
messages: Membrane

216142:LT40 RS12115
gene id: 216142:LT40_RS12115
uniprot id: A0A089YNW0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

216142:LT40 RS09425
gene id: 216142:LT40_RS09425
uniprot id: A0A089YPU0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

216142:LT40 RS03410
gene id: 216142:LT40_RS03410
uniprot id: A0A089ZPU8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Cell membrane
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

216142:LT40 RS04750
gene id: 216142:LT40_RS04750
uniprot id: A0A089YK61
names: Similarity
messages: Belongs to the pyruvate kinase family.

216142:LT40 RS09405
gene id: 216142:LT40_RS09405
uniprot id: A0A089YV59
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Catalyzes the phosphorylation of D-xylulose to D-xylulose 5-phosphate.

216142:LT40 RS15565
gene id: 216142:LT40_RS15565
uniprot id: A0A089YWJ1
names: Function
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

216142:LT40 RS11270
gene id: 216142:LT40_RS11270
uniprot id: A0A089YW69
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LolA family.
messages: Monomer.
messages: Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane).
messages: Periplasm

216142:LT40 RS07320
gene id: 216142:LT40_RS07320
uniprot id: A0A089YS64
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 3 family. NagZ subfamily.
messages: Cytoplasm
messages: Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide-linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N-acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides.

216142:LT40 RS07325
gene id: 216142:LT40_RS07325
uniprot id: A0A089YLF9
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

216142:LT40 RS02515
gene id: 216142:LT40_RS02515
uniprot id: A0A089YPP5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CheZ family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P).

216142:LT40 RS16915
gene id: 216142:LT40_RS16915
uniprot id: A0A089YTU7
names: Function
names: Similarity
names: Subunit
messages: Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division.
messages: Belongs to the ZapA family. Type 1 subfamily.
messages: Homodimer. Interacts with FtsZ.

216142:LT40 RS17435
gene id: 216142:LT40_RS17435
uniprot id: A0A089ZRC4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

216142:LT40 RS04020
gene id: 216142:LT40_RS04020
uniprot id: A0A089YSF1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsL family.
messages: Cell inner membrane
messages: Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.
messages: Membrane
messages: Part of a complex composed of FtsB, FtsL and FtsQ.

216142:LT40 RS09980
gene id: 216142:LT40_RS09980
uniprot id: A0A089YMT7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

216142:LT40 RS00470
gene id: 216142:LT40_RS00470
uniprot id: A0A089YHW3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxA subfamily.
messages: Cytoplasm
messages: Homotrimer.
messages: Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

216142:LT40 RS04605
gene id: 216142:LT40_RS04605
uniprot id: A0A089YSR1
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

216142:LT40 RS10275
gene id: 216142:LT40_RS10275
uniprot id: A0A089YTR8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NfuA family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is presumably bound at the interface of two monomers.
messages: Homodimer.
messages: Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins.

216142:LT40 RS14465
gene id: 216142:LT40_RS14465
uniprot id: A0A089YVZ0
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Member of the two-component regulatory system NtrB/NtrC, which controls expression of the nitrogen-regulated (ntr) genes in response to nitrogen limitation. Phosphorylated NtrC binds directly to DNA and stimulates the formation of open promoter-sigma54-RNA polymerase complexes.

216142:LT40 RS03160
gene id: 216142:LT40_RS03160
uniprot id: A0A089YJB5
names: Similarity
messages: Belongs to the GcvT family.

216142:LT40 RS19595
gene id: 216142:LT40_RS19595
uniprot id: A0A089YSX8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP E family.
messages: Cytoplasm

216142:LT40 RS17185
gene id: 216142:LT40_RS17185
uniprot id: A0A089ZRB4
names: Cofactor
names: Similarity
messages: Belongs to the RimK family.
messages: Binds 2 magnesium or manganese ions per subunit.

216142:LT40 RS15920
gene id: 216142:LT40_RS15920
uniprot id: A0A089YWS8
names: Similarity
messages: Belongs to the sulfatase family.

216142:LT40 RS14695
gene id: 216142:LT40_RS14695
uniprot id: A0A089ZR20
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily. RsmD family.
messages: Specifically methylates the guanine in position 966 of 16S rRNA in the assembled 30S particle.

216142:LT40 RS16160
gene id: 216142:LT40_RS16160
uniprot id: A0A089YZH4
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

216142:LT40 RS14550
gene id: 216142:LT40_RS14550
uniprot id: A0A089YQ61
names: Similarity
messages: Belongs to the prokaryotic GSH synthase family.

216142:LT40 RS06475
gene id: 216142:LT40_RS06475
uniprot id: A0A089YTQ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

216142:LT40 RS10960
gene id: 216142:LT40_RS10960
uniprot id: A0A089YQQ2
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

216142:LT40 RS18385
gene id: 216142:LT40_RS18385
uniprot id: A0A089YUL3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

216142:LT40 RS03810
gene id: 216142:LT40_RS03810
uniprot id: A0A089YSB4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the KdsC family.
messages: Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate.
messages: Homotetramer.

216142:LT40 RS07700
gene id: 216142:LT40_RS07700
uniprot id: A0A089YP00
names: Subcellular Location Annotation
messages: Membrane

216142:LT40 RS07045
gene id: 216142:LT40_RS07045
uniprot id: A0A089YS02
names: Similarity
messages: Belongs to the 2-oxoadipate dioxygenase/decarboxylase family.

216142:LT40 RS19420
gene id: 216142:LT40_RS19420
uniprot id: A0A089YSV2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

216142:LT40 RS13370
gene id: 216142:LT40_RS13370
uniprot id: A0A089YX96
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. CmoM family.
messages: Catalyzes the methylation of 5-carboxymethoxyuridine (cmo5U) to form 5-methoxycarbonylmethoxyuridine (mcmo5U) at position 34 in tRNAs.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

216142:LT40 RS19590
gene id: 216142:LT40_RS19590
uniprot id: A0A089YYK1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Cell inner membrane
messages: Membrane

216142:LT40 RS02950
gene id: 216142:LT40_RS02950
uniprot id: A0A089YPZ2
names: Function
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

216142:LT40 RS17425
gene id: 216142:LT40_RS17425
uniprot id: A0A089YU24
names: Function
messages: Repressor involved in choline regulation of the bet genes.
messages: Repressor involved in the biosynthesis of the osmoprotectant glycine betaine. It represses transcription of the choline transporter BetT and the genes of BetAB involved in the synthesis of glycine betaine.

216142:LT40 RS18645
gene id: 216142:LT40_RS18645
uniprot id: A0A089Z0T9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

216142:LT40 RS20770
gene id: 216142:LT40_RS20770
uniprot id: A0A089YZ38
names: Subcellular Location Annotation
messages: Membrane

216142:LT40 RS06355
gene id: 216142:LT40_RS06355
uniprot id: A0A089YRP8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

216142:LT40 RS10330
gene id: 216142:LT40_RS10330
uniprot id: A0A089YN06
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CopD family.
messages: Cell inner membrane
messages: Involved in copper resistance.
messages: Membrane

216142:LT40 RS18415
gene id: 216142:LT40_RS18415
uniprot id: A0A089Z0N5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

216142:LT40 RS04080
gene id: 216142:LT40_RS04080
uniprot id: A0A089YQF5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

216142:LT40 RS15040
gene id: 216142:LT40_RS15040
uniprot id: A0A089ZR32
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

216142:LT40 RS15420
gene id: 216142:LT40_RS15420
uniprot id: A0A089YWG6
names: Similarity
messages: Belongs to the barstar family.

216142:LT40 RS16650
gene id: 216142:LT40_RS16650
uniprot id: A0A089YX76
names: Similarity
messages: Belongs to the 2-oxoadipate dioxygenase/decarboxylase family.

216142:LT40 RS20425
gene id: 216142:LT40_RS20425
uniprot id: A0A089ZRN4
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OpgD/OpgG family.
messages: Periplasm
messages: Predicted to be exported by the Tat system. The position of the signal peptide cleavage has not been experimentally proven.
messages: Probably involved in the control of the structural glucose backbone of osmoregulated periplasmic glucans (OPGs).

216142:LT40 RS12985
gene id: 216142:LT40_RS12985
uniprot id: A0A089YPB9
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

216142:LT40 RS02455
gene id: 216142:LT40_RS02455
uniprot id: A0A089YRK4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliM family.
messages: Cell inner membrane
messages: FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
messages: Membrane

216142:LT40 RS14355
gene id: 216142:LT40_RS14355
uniprot id: A0A089ZR07
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

216142:LT40 RS05870
gene id: 216142:LT40_RS05870
uniprot id: A0A089YRH3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

216142:LT40 RS06755
gene id: 216142:LT40_RS06755
uniprot id: A0A089ZQ74
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

216142:LT40 RS17415
gene id: 216142:LT40_RS17415
uniprot id: A0A089YXI7
names: Function
names: Similarity
messages: Belongs to the GMC oxidoreductase family.
messages: Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate.

216142:LT40 RS12595
gene id: 216142:LT40_RS12595
uniprot id: A0A089YUX8
names: Cofactor
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cell inner membrane
messages: Membrane
messages: Membrane-anchoring subunit of succinate dehydrogenase (SDH).
messages: Part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur protein, plus two membrane-anchoring proteins, SdhC and SdhD.
messages: The heme is bound between the two transmembrane subunits.

216142:LT40 RS15995
gene id: 216142:LT40_RS15995
uniprot id: A0A089YWU3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

216142:LT40 RS13845
gene id: 216142:LT40_RS13845
uniprot id: A0A089YPV3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0126 family.
messages: Membrane

216142:LT40 RS05185
gene id: 216142:LT40_RS05185
uniprot id: A0A089ZQ16
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

216142:LT40 RS03955
gene id: 216142:LT40_RS03955
uniprot id: A0A089YM06
names: Similarity
messages: Belongs to the GST superfamily. HSP26 family.

216142:LT40 RS18900
gene id: 216142:LT40_RS18900
uniprot id: A0A089ZRH7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methylthiotransferase family. MiaB subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
messages: Cytoplasm
messages: Monomer.

216142:LT40 RS18145
gene id: 216142:LT40_RS18145
uniprot id: A0A089ZRF0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

216142:LT40 RS00340
gene id: 216142:LT40_RS00340
uniprot id: A0A089YHU5
names: Similarity
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.

216142:LT40 RS14360
gene id: 216142:LT40_RS14360
uniprot id: A0A089YVX5
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

216142:LT40 RS14950
gene id: 216142:LT40_RS14950
uniprot id: A0A089YSP6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

216142:LT40 RS05630
gene id: 216142:LT40_RS05630
uniprot id: A0A089ZQ32
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

216142:LT40 RS14005
gene id: 216142:LT40_RS14005
uniprot id: A0A089YPX4
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

216142:LT40 RS17055
gene id: 216142:LT40_RS17055
uniprot id: A0A089ZRA9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

216142:LT40 RS20375
gene id: 216142:LT40_RS20375
uniprot id: A0A089YTA3
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

216142:LT40 RS05210
gene id: 216142:LT40_RS05210
uniprot id: A0A089ZQ17
names: Similarity
messages: Belongs to the peptidase M42 family.

216142:LT40 RS20180
gene id: 216142:LT40_RS20180
uniprot id: A0A089YT76
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

216142:LT40 RS04100
gene id: 216142:LT40_RS04100
uniprot id: A0A089ZPX5
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArgJ family.
messages: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.
messages: Cytoplasm
messages: Heterotetramer of two alpha and two beta chains.
messages: Some bacteria possess a monofunctional ArgJ, i.e., capable of catalyzing only the fifth step of the arginine biosynthetic pathway.

216142:LT40 RS04940
gene id: 216142:LT40_RS04940
uniprot id: A0A089YMJ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

216142:LT40 RS01510
gene id: 216142:LT40_RS01510
uniprot id: A0A089YKL8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Cell inner membrane

216142:LT40 RS16510
gene id: 216142:LT40_RS16510
uniprot id: A0A089YTM6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.

216142:LT40 RS04995
gene id: 216142:LT40_RS04995
uniprot id: A0A089YSZ9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.
messages: Binds 1 S-adenosyl-L-methionine per subunit.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

216142:LT40 RS02105
gene id: 216142:LT40_RS02105
uniprot id: A0A089YKY9
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

216142:LT40 RS07340
gene id: 216142:LT40_RS07340
uniprot id: A0A089ZQ96
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

216142:LT40 RS06315
gene id: 216142:LT40_RS06315
uniprot id: A0A089YTM3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

216142:LT40 RS06430
gene id: 216142:LT40_RS06430
uniprot id: A0A089ZQ62
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the selenophosphate synthase 1 family. Class I subfamily.
messages: Binds 1 Mg(2+) ion per monomer.
messages: Homodimer.
messages: Synthesizes selenophosphate from selenide and ATP.

216142:LT40 RS13665
gene id: 216142:LT40_RS13665
uniprot id: A0A089YS46
names: Similarity
messages: Belongs to the ABC transporter superfamily.

216142:LT40 RS08285
gene id: 216142:LT40_RS08285
uniprot id: A0A089YUP4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

216142:LT40 RS09390
gene id: 216142:LT40_RS09390
uniprot id: A0A089YTA0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

216142:LT40 RS11425
gene id: 216142:LT40_RS11425
uniprot id: A0A089YW92
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAN1 family.
messages: Nuclease required for the repair of DNA interstrand cross-links (ICL). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions.
messages: Nucleus

216142:LT40 RS17865
gene id: 216142:LT40_RS17865
uniprot id: A0A089YXP4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BexD/CtrA/VexA family.
messages: Cell outer membrane
messages: Membrane

216142:LT40 RS08225
gene id: 216142:LT40_RS08225
uniprot id: A0A089YM11
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

216142:LT40 RS04965
gene id: 216142:LT40_RS04965
uniprot id: A0A089YMK4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ExbB/TolQ family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

216142:LT40 RS14070
gene id: 216142:LT40_RS14070
uniprot id: A0A089YYD3
names: Similarity
messages: Belongs to the NtaA/SnaA/DszA monooxygenase family.

216142:LT40 RS17265
gene id: 216142:LT40_RS17265
uniprot id: A0A089YXG6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
messages: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.
messages: Homodimer.

216142:LT40 RS15990
gene id: 216142:LT40_RS15990
uniprot id: A0A089ZR67
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

216142:LT40 RS11040
gene id: 216142:LT40_RS11040
uniprot id: A0A089YW38
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 13 family.
messages: Cytoplasm

216142:LT40 RS00725
gene id: 216142:LT40_RS00725
uniprot id: A0A089YNU2
names: Subunit
messages: Homodimer.

216142:LT40 RS11355
gene id: 216142:LT40_RS11355
uniprot id: A0A089ZQP5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 3 family.
messages: Cell membrane
messages: NDH-1 is composed of 13 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

216142:LT40 RS06345
gene id: 216142:LT40_RS06345
uniprot id: A0A089ZQ59
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

216142:LT40 RS06655
gene id: 216142:LT40_RS06655
uniprot id: A0A089ZQ70
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

216142:LT40 RS05135
gene id: 216142:LT40_RS05135
uniprot id: A0A089ZQ14
names: Similarity
messages: Belongs to the cysteine dioxygenase family.

216142:LT40 RS09185
gene id: 216142:LT40_RS09185
uniprot id: A0A089YMF2
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

216142:LT40 RS07720
gene id: 216142:LT40_RS07720
uniprot id: A0A089YLP9
names: Subcellular Location Annotation
messages: Membrane

216142:LT40 RS20165
gene id: 216142:LT40_RS20165
uniprot id: A0A089Z1K4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell outer membrane

216142:LT40 RS15935
gene id: 216142:LT40_RS15935
uniprot id: A0A089YZC4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the aerobic coproporphyrinogen-III oxidase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX.

216142:LT40 RS16365
gene id: 216142:LT40_RS16365
uniprot id: A0A089YZK2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Membrane

216142:LT40 RS06135
gene id: 216142:LT40_RS06135
uniprot id: A0A089YN86
names: Similarity
messages: Belongs to the eIF-2B alpha/beta/delta subunits family. MtnA subfamily.

216142:LT40 RS12265
gene id: 216142:LT40_RS12265
uniprot id: A0A089YWM8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
messages: Cell inner membrane
messages: Membrane

216142:LT40 RS12795
gene id: 216142:LT40_RS12795
uniprot id: A0A089YV26
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DksA family.
messages: Cytoplasm
messages: Interacts directly with the RNA polymerase.
messages: Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters. Also required for regulation of fis expression.

216142:LT40 RS12745
gene id: 216142:LT40_RS12745
uniprot id: A0A089YV12
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

216142:LT40 RS00880
gene id: 216142:LT40_RS00880
uniprot id: A0A089YNW6
names: Similarity
messages: Belongs to the leucine-binding protein family.

216142:LT40 RS07695
gene id: 216142:LT40_RS07695
uniprot id: A0A089YLP4
names: Subcellular Location Annotation
messages: Membrane

216142:LT40 RS16910
gene id: 216142:LT40_RS16910
uniprot id: A0A089YRH2
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

216142:LT40 RS07105
gene id: 216142:LT40_RS07105
uniprot id: A0A089YS12
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

216142:LT40 RS18585
gene id: 216142:LT40_RS18585
uniprot id: A0A089YUR5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.
messages: Forms an icosahedral capsid composed of 60 subunits, arranged as a dodecamer of pentamers.

216142:LT40 RS02490
gene id: 216142:LT40_RS02490
uniprot id: A0A089YPP1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.
messages: Cell membrane
messages: Membrane
messages: Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

216142:LT40 RS00085
gene id: 216142:LT40_RS00085
uniprot id: A0A089YNK8
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

216142:LT40 RS14350
gene id: 216142:LT40_RS14350
uniprot id: A0A089YYI6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Membrane

216142:LT40 RS13975
gene id: 216142:LT40_RS13975
uniprot id: A0A089YVR6
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase class-III family.

216142:LT40 RS19235
gene id: 216142:LT40_RS19235
uniprot id: A0A089YSS0
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the shikimate dehydrogenase family.
messages: Homodimer.
messages: Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

216142:LT40 RS05440
gene id: 216142:LT40_RS05440
uniprot id: A0A089YMY4
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

216142:LT40 RS07455
gene id: 216142:LT40_RS07455
uniprot id: A0A089YLJ0
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

216142:LT40 RS19960
gene id: 216142:LT40_RS19960
uniprot id: A0A089ZRL7
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

216142:LT40 RS20155
gene id: 216142:LT40_RS20155
uniprot id: A0A089YT71
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

216142:LT40 RS17765
gene id: 216142:LT40_RS17765
uniprot id: A0A089YXM9
names: Similarity
messages: Belongs to the NodU/CmcH family.

216142:LT40 RS06390
gene id: 216142:LT40_RS06390
uniprot id: A0A089YL05
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

216142:LT40 RS14415
gene id: 216142:LT40_RS14415
uniprot id: A0A089YVY0
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FBPase class 1 family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

216142:LT40 RS13000
gene id: 216142:LT40_RS13000
uniprot id: A0A089ZQV6
names: Similarity
messages: Belongs to the UPF0125 (RnfH) family.

216142:LT40 RS02320
gene id: 216142:LT40_RS02320
uniprot id: A0A089YIU3
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.

216142:LT40 RS19970
gene id: 216142:LT40_RS19970
uniprot id: A0A089YT43
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methyltransferase superfamily. RsmC family.
messages: Cytoplasm
messages: Monomer.
messages: Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle.

216142:LT40 RS12020
gene id: 216142:LT40_RS12020
uniprot id: A0A089YWI3
names: Similarity
messages: Belongs to the TPP enzyme family.

216142:LT40 RS00375
gene id: 216142:LT40_RS00375
uniprot id: A0A089YQJ1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

216142:LT40 RS15970
gene id: 216142:LT40_RS15970
uniprot id: A0A089YWT8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Cytoplasm
messages: Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.

216142:LT40 RS14215
gene id: 216142:LT40_RS14215
uniprot id: A0A089YQ07
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial secretin family. PilQ subfamily.
messages: Cell outer membrane
messages: Membrane

216142:LT40 RS12835
gene id: 216142:LT40_RS12835
uniprot id: A0A089YWX9
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

216142:LT40 RS16455
gene id: 216142:LT40_RS16455
uniprot id: A0A089YR97
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ExbD/TolR family.
messages: Cell inner membrane
messages: Cell membrane
messages: Involved in the TonB-dependent energy-dependent transport of various receptor-bound substrates.
messages: Membrane
messages: The accessory proteins ExbB and ExbD seem to form a complex with TonB.

216142:LT40 RS02450
gene id: 216142:LT40_RS02450
uniprot id: A0A089YL68
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliL family.
messages: Cell inner membrane
messages: Controls the rotational direction of flagella during chemotaxis.
messages: Membrane

216142:LT40 RS04315
gene id: 216142:LT40_RS04315
uniprot id: A0A089YJW4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
messages: Membrane

216142:LT40 RS11225
gene id: 216142:LT40_RS11225
uniprot id: A0A089ZQP0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

216142:LT40 RS03045
gene id: 216142:LT40_RS03045
uniprot id: A0A089YRY3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MoaC family.
messages: Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
messages: Homohexamer; trimer of dimers.

216142:LT40 RS14250
gene id: 216142:LT40_RS14250
uniprot id: A0A089YYG6
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

216142:LT40 RS07275
gene id: 216142:LT40_RS07275
uniprot id: A0A089YLE7
names: Function
names: Similarity
names: Subunit
messages: Heterotetramer of two alpha chains (FadB) and two beta chains (FadA).
messages: In the C-terminal section; belongs to the 3-hydroxyacyl-CoA dehydrogenase family.
messages: In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family.
messages: Involved in the aerobic and anaerobic degradation of long-chain fatty acids via beta-oxidation cycle. Catalyzes the formation of 3-oxoacyl-CoA from enoyl-CoA via L-3-hydroxyacyl-CoA. It can also use D-3-hydroxyacyl-CoA and cis-3-enoyl-CoA as substrate.

216142:LT40 RS17320
gene id: 216142:LT40_RS17320
uniprot id: A0A089YRP2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

216142:LT40 RS15405
gene id: 216142:LT40_RS15405
uniprot id: A0A089YZ16
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

216142:LT40 RS00365
gene id: 216142:LT40_RS00365
uniprot id: A0A089YHU9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type 2 tetrahydrodipicolinate N-succinyltransferase family.
messages: Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2-amino-6-oxopimelate using succinyl-CoA.
messages: Cytoplasm
messages: Homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

216142:LT40 RS11230
gene id: 216142:LT40_RS11230
uniprot id: A0A089YUB2
names: Similarity
messages: Belongs to the pirin family.

216142:LT40 RS11760
gene id: 216142:LT40_RS11760
uniprot id: A0A089YUI8
names: Similarity
messages: Belongs to the DNA polymerase type-Y family.

216142:LT40 RS03660
gene id: 216142:LT40_RS03660
uniprot id: A0A089YS84
names: Similarity
messages: Belongs to the DapA family.

216142:LT40 RS13315
gene id: 216142:LT40_RS13315
uniprot id: A0A089YRU2
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Bcr/CmlA family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

216142:LT40 RS01175
gene id: 216142:LT40_RS01175
uniprot id: A0A089YI74
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LysR transcriptional regulatory family.
messages: Cytoplasm

216142:LT40 RS12925
gene id: 216142:LT40_RS12925
uniprot id: A0A089ZQV3
names: Function
names: Similarity
messages: Belongs to the DHPS family.
messages: Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives.

216142:LT40 RS06150
gene id: 216142:LT40_RS06150
uniprot id: A0A089YRL8
names: Function
names: Subcellular Location Annotation
messages: Catalyzes the Claisen rearrangement of chorismate to prephenate and the decarboxylation/dehydration of prephenate to phenylpyruvate.
messages: Cytoplasm

216142:LT40 RS12625
gene id: 216142:LT40_RS12625
uniprot id: A0A089YP54
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

216142:LT40 RS17840
gene id: 216142:LT40_RS17840
uniprot id: A0A089YXP1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. PqqE family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the cross-linking of a glutamate residue and a tyrosine residue in the PqqA protein as part of the biosynthesis of pyrroloquinoline quinone (PQQ).
messages: Interacts with PqqD. The interaction is necessary for activity of PqqE.

216142:LT40 RS00485
gene id: 216142:LT40_RS00485
uniprot id: A0A089ZPI9
names: Subcellular Location Annotation
messages: Cytoplasm

216142:LT40 RS12920
gene id: 216142:LT40_RS12920
uniprot id: A0A089YWZ5
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

216142:LT40 RS18030
gene id: 216142:LT40_RS18030
uniprot id: A0A089YUE8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsY family.
messages: Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Probably interacts with PlsX.

216142:LT40 RS08330
gene id: 216142:LT40_RS08330
uniprot id: A0A089YPE5
names: Similarity
names: Subunit
messages: Belongs to the group II decarboxylase family.
messages: Homotetramer.

216142:LT40 RS00350
gene id: 216142:LT40_RS00350
uniprot id: A0A089YQI7
names: Similarity
messages: Belongs to the ubiquitin-activating E1 family. UBA5 subfamily.

216142:LT40 RS16460
gene id: 216142:LT40_RS16460
uniprot id: A0A089YTL7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the exbB/tolQ family.
messages: Cell inner membrane
messages: Involved in the TonB-dependent energy-dependent transport of various receptor-bound substrates. Protects ExbD from proteolytic degradation and functionally stabilizes TonB.
messages: Membrane
messages: The accessory proteins ExbB and ExbD seem to form a complex with TonB.

216142:LT40 RS01125
gene id: 216142:LT40_RS01125
uniprot id: A0A089ZPL3
names: Similarity
names: Subunit
messages: Belongs to the threonine aldolase family.
messages: Homotetramer.

216142:LT40 RS09660
gene id: 216142:LT40_RS09660
uniprot id: A0A089YPY2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Cell inner membrane
messages: Condenses choline with CDP-diglyceride to produce phosphatidylcholine and CMP.
messages: Membrane

216142:LT40 RS17030
gene id: 216142:LT40_RS17030
uniprot id: A0A089ZRA8
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

216142:LT40 RS03265
gene id: 216142:LT40_RS03265
uniprot id: A0A089YLQ2
names: Function
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.
messages: Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.

216142:LT40 RS00570
gene id: 216142:LT40_RS00570
uniprot id: A0A089YHX6
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

216142:LT40 RS02305
gene id: 216142:LT40_RS02305
uniprot id: A0A089ZPQ6
names: Function
names: Similarity
messages: Belongs to the FlgD family.
messages: Required for flagellar hook formation. May act as a scaffolding protein.

216142:LT40 RS18140
gene id: 216142:LT40_RS18140
uniprot id: A0A089Z0I3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

216142:LT40 RS16325
gene id: 216142:LT40_RS16325
uniprot id: A0A089YX24
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)- to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Homodimer.

216142:LT40 RS17335
gene id: 216142:LT40_RS17335
uniprot id: A0A089ZRC0
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

216142:LT40 RS03880
gene id: 216142:LT40_RS03880
uniprot id: A0A089YLZ3
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

216142:LT40 RS09300
gene id: 216142:LT40_RS09300
uniprot id: A0A089YPS3
names: Similarity
messages: Belongs to the EfeM/EfeO family.

216142:LT40 RS07265
gene id: 216142:LT40_RS07265
uniprot id: A0A089ZQ93
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal stress protein A family.
messages: Cytoplasm

216142:LT40 RS03990
gene id: 216142:LT40_RS03990
uniprot id: A0A089YM12
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SIS family. GmhA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate.
messages: Cytoplasm
messages: Homotetramer.
messages: The reaction produces a racemic mixture of D-glycero-alpha-D-manno-heptose 7-phosphate and D-glycero-beta-D-manno-heptose 7-phosphate.

216142:LT40 RS00075
gene id: 216142:LT40_RS00075
uniprot id: A0A089YQF3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. Cx-SAM synthase family.
messages: Catalyzes the conversion of S-adenosyl-L-methionine (SAM) to carboxy-S-adenosyl-L-methionine (Cx-SAM).
messages: Homodimer.

216142:LT40 RS18425
gene id: 216142:LT40_RS18425
uniprot id: A0A089YXY8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

216142:LT40 RS00825
gene id: 216142:LT40_RS00825
uniprot id: A0A089ZPK2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the helicase family. DinG subfamily. Type 1 sub-subfamily.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA-dependent ATPase and 5'-3' DNA helicase.

216142:LT40 RS19795
gene id: 216142:LT40_RS19795
uniprot id: A0A089YVC4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

216142:LT40 RS06085
gene id: 216142:LT40_RS06085
uniprot id: A0A089YN80
names: Similarity
messages: Belongs to the BolA/IbaG family.

216142:LT40 RS09055
gene id: 216142:LT40_RS09055
uniprot id: A0A089ZQG0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Binds 1 Mg(2+) ion per monomer.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

216142:LT40 RS11400
gene id: 216142:LT40_RS11400
uniprot id: A0A089YW88
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 13 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

216142:LT40 RS05105
gene id: 216142:LT40_RS05105
uniprot id: A0A089ZQ13
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

216142:LT40 RS02995
gene id: 216142:LT40_RS02995
uniprot id: A0A089YRX5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

216142:LT40 RS15780
gene id: 216142:LT40_RS15780
uniprot id: A0A089YZ87
names: Subcellular Location Annotation
messages: Membrane

216142:LT40 RS14855
gene id: 216142:LT40_RS14855
uniprot id: A0A089ZR26
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily.
messages: Catalyzes the transfer of the alpha-amino group from S-adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only aminotransferase known to utilize SAM as an amino donor.
messages: Cytoplasm
messages: Homodimer.

216142:LT40 RS16845
gene id: 216142:LT40_RS16845
uniprot id: A0A089YZU2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Membrane

216142:LT40 RS00115
gene id: 216142:LT40_RS00115
uniprot id: A0A089YHR7
names: Similarity
messages: Belongs to the OprB family.

216142:LT40 RS18440
gene id: 216142:LT40_RS18440
uniprot id: A0A089Z0P0
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

216142:LT40 RS19085
gene id: 216142:LT40_RS19085
uniprot id: A0A089YSP3
names: Function
names: Similarity
messages: Belongs to the AB hydrolase superfamily. Hydrolase RutD family.
messages: Involved in pyrimidine catabolism. May facilitate the hydrolysis of carbamate, a reaction that can also occur spontaneously.

216142:LT40 RS18895
gene id: 216142:LT40_RS18895
uniprot id: A0A089Z0Z2
names: Similarity
messages: Belongs to the PhoH family.

216142:LT40 RS08240
gene id: 216142:LT40_RS08240
uniprot id: A0A089ZQC9
names: Subcellular Location Annotation
messages: Membrane

216142:LT40 RS17660
gene id: 216142:LT40_RS17660
uniprot id: A0A089YU76
names: Function
messages: Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).

216142:LT40 RS12840
gene id: 216142:LT40_RS12840
uniprot id: A0A089ZQV0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm

216142:LT40 RS07975
gene id: 216142:LT40_RS07975
uniprot id: A0A089YLU9
names: Subcellular Location Annotation
messages: Membrane

216142:LT40 RS04400
gene id: 216142:LT40_RS04400
uniprot id: A0A089YSL8
names: Subcellular Location Annotation
messages: Membrane