214684:CNG02980
gene id: 214684:CNG02980
uniprot id: Q5KDS2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

214684:CNA02700
gene id: 214684:CNA02700
uniprot id: Q5KPI3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TCP-1 chaperonin family.
messages: Cytoplasm
messages: Heterooligomeric complex of about 850 to 900 kDa that forms two stacked rings, 12 to 16 nm in diameter.
messages: Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. Known to play a role, in vitro, in the folding of actin and tubulin.

214684:CNK00690
gene id: 214684:CNK00690
uniprot id: Q5K9U9
names: Similarity
messages: Belongs to the AAA ATPase family. PCH2 subfamily.

214684:CNM00630
gene id: 214684:CNM00630
uniprot id: Q5K806
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

214684:CNC04930
gene id: 214684:CNC04930
uniprot id: Q5KJY4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.
messages: Cytoplasm
messages: Hydrolyzes ATP, and can also hydrolyze GTP with lower efficiency. Has lower affinity for GTP.
messages: Monomer.

214684:CNA02260
gene id: 214684:CNA02260
uniprot id: Q5KPM4
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.

214684:CNA04280
gene id: 214684:CNA04280
uniprot id: Q5KP40
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TCP-1 chaperonin family.
messages: Cytoplasm

214684:CNB01970
gene id: 214684:CNB01970
uniprot id: P0CQ98
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: ATP-dependent RNA helicase involved spliceosome assembly and in nuclear splicing. Catalyzes an ATP-dependent conformational change of U2 snRNP. Bridges U1 and U2 snRNPs and enables stable U2 snRNP association with intron RNA (By similarity).
messages: Belongs to the DEAD box helicase family. DDX46/PRP5 subfamily.
messages: Nucleus
messages: The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.

214684:CNE02610
gene id: 214684:CNE02610
uniprot id: Q5KGR6
names: Similarity
messages: Belongs to the NDK family.

214684:CNI01470
gene id: 214684:CNI01470
uniprot id: Q5KBT5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNAP family.
messages: Membrane
messages: Required for vesicular transport between the endoplasmic reticulum and the Golgi apparatus.

214684:CNA00550
gene id: 214684:CNA00550
uniprot id: Q5KQ41
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EMP24/GP25L family.
messages: Membrane

214684:CNC05240
gene id: 214684:CNC05240
uniprot id: Q5KJV4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mL49 family.
messages: Mitochondrion

214684:CNH00390
gene id: 214684:CNH00390
uniprot id: Q5KCA9
names: Subcellular Location Annotation
messages: nucleolus

214684:CNH02990
gene id: 214684:CNH02990
uniprot id: Q5KD18
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

214684:CNG01310
gene id: 214684:CNG01310
uniprot id: Q5KE92
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

214684:CNL04600
gene id: 214684:CNL04600
uniprot id: Q5K8T1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the USE1 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

214684:CND02580
gene id: 214684:CND02580
uniprot id: Q5KIL0
names: Similarity
messages: Belongs to the FHIP family.

214684:CNC01150
gene id: 214684:CNC01150
uniprot id: Q5KL12
names: Subcellular Location Annotation
messages: Nucleus

214684:CNC07110
gene id: 214684:CNC07110
uniprot id: Q5KJB6
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

214684:CNC03020
gene id: 214684:CNC03020
uniprot id: P0CO20
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transferase hexapeptide repeat family.
messages: Cytoplasm
messages: Involved in cell wall synthesis where it is required for glycosylation. Involved in cell cycle progression through cell-size checkpoint (By similarity).

214684:CNE01010
gene id: 214684:CNE01010
uniprot id: Q5KH73
names: Subcellular Location Annotation
messages: Cytoplasm

214684:CNN02260
gene id: 214684:CNN02260
uniprot id: Q5K6U3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 72 family.
messages: Cell membrane
messages: Splits internally a 1,3-beta-glucan molecule and transfers the newly generated reducing end (the donor) to the non-reducing end of another 1,3-beta-glucan molecule (the acceptor) forming a 1,3-beta linkage, resulting in the elongation of 1,3-beta-glucan chains in the cell wall.

214684:CNF01460
gene id: 214684:CNF01460
uniprot id: Q5KFK2
names: Subcellular Location Annotation
messages: Membrane

214684:CNC00180
gene id: 214684:CNC00180
uniprot id: Q5KLA5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat SWD2 family.
messages: Nucleus

214684:CNM00010
gene id: 214684:CNM00010
uniprot id: Q5K860
names: Subcellular Location Annotation
messages: Membrane

214684:CNC05610
gene id: 214684:CNC05610
uniprot id: Q5KJR5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CMC family.
messages: Mitochondrion inner membrane
messages: Required for mitochondrial cytochrome c oxidase (COX) assembly and respiration.

214684:CND04940
gene id: 214684:CND04940
uniprot id: Q5KHX8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase PH family.
messages: nucleolus

214684:CNI03670
gene id: 214684:CNI03670
uniprot id: Q5KB61
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNU66/SART1 family.
messages: Nucleus

214684:CNC04790
gene id: 214684:CNC04790
uniprot id: Q5KJZ9
names: Similarity
messages: Belongs to the PHP hydrolase family. HisK subfamily.

214684:CNE05130
gene id: 214684:CNE05130
uniprot id: Q5KG23
names: Similarity
messages: Belongs to the acetyltransferase family. ARD1 subfamily.

214684:CNA00480
gene id: 214684:CNA00480
uniprot id: Q5KQ47
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TCP-1 chaperonin family.
messages: Cytoplasm

214684:CNC03010
gene id: 214684:CNC03010
uniprot id: Q5KKH3
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL24 family.

214684:CNB01140
gene id: 214684:CNB01140
uniprot id: Q5KMM8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleoporin GLFG family.
messages: nuclear pore complex

214684:CNE00720
gene id: 214684:CNE00720
uniprot id: Q5KHA4
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

214684:CND03830
gene id: 214684:CND03830
uniprot id: Q5KI86
names: Similarity
messages: Belongs to the WD repeat G protein beta family.

214684:CNF00090
gene id: 214684:CNF00090
uniprot id: P0CP26
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NOP5/NOP56 family.
messages: Required for pre-18S rRNA processing. May bind microtubules (By similarity).
messages: nucleolus

214684:CNE04240
gene id: 214684:CNE04240
uniprot id: Q5KGB2
names: Similarity
messages: Belongs to the adaptor complexes small subunit family.

214684:CND03010
gene id: 214684:CND03010
uniprot id: Q5KIG9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GOT1 family.
messages: Golgi apparatus membrane
messages: Membrane

214684:CNG01580
gene id: 214684:CNG01580
uniprot id: Q5KE65
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

214684:CNH03610
gene id: 214684:CNH03610
uniprot id: Q5KD80
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1A family.
messages: Cytoplasm
messages: Nucleus
messages: The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits.

214684:CNC06360
gene id: 214684:CNC06360
uniprot id: P0CQ72
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: ATP-dependent RNA helicase involved in 40S ribosomal subunit biogenesis. Required for the processing and cleavage of 35S pre-rRNA at sites A0, A1, and A2, leading to mature 18S rRNA (By similarity).
messages: Belongs to the DEAD box helicase family. DDX48/FAL1 subfamily.
messages: The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.
messages: nucleolus

214684:CNG02720
gene id: 214684:CNG02720
uniprot id: Q5KDU8
names: Similarity
messages: Belongs to the Mo25 family.

214684:CNE03520
gene id: 214684:CNE03520
uniprot id: Q5KGI1
names: Caution
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

214684:CNK02640
gene id: 214684:CNK02640
uniprot id: P0CM24
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATPase required for the post-translational delivery of tail-anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. Subsequently, the homodimer reverts towards the open dimer state, lowering its affinity for the membrane-bound receptor, and returning it to the cytosol to initiate a new round of targeting.
messages: Belongs to the arsA ATPase family.
messages: Cytoplasm
messages: Endoplasmic reticulum
messages: Homodimer.

214684:CNC06010
gene id: 214684:CNC06010
uniprot id: Q5KJM4
names: Subcellular Location Annotation
messages: Membrane

214684:CNJ01500
gene id: 214684:CNJ01500
uniprot id: Q5KAJ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC41A transporter family.
messages: Membrane

214684:CNL03930
gene id: 214684:CNL03930
uniprot id: Q5K8Z6
names: Similarity
messages: Belongs to the 14-3-3 family.

214684:CNE04500
gene id: 214684:CNE04500
uniprot id: Q5KG84
names: Similarity
messages: Belongs to the sirtuin family. Class I subfamily.

214684:CNC05480
gene id: 214684:CNC05480
uniprot id: Q5KJT0
names: Similarity
messages: Belongs to the cytochrome c oxidase subunit 6A family.

214684:CNC02480
gene id: 214684:CNC02480
uniprot id: Q5KKM8
names: Similarity
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.

214684:CND01570
gene id: 214684:CND01570
uniprot id: Q5KIV9
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

214684:CNK03110
gene id: 214684:CNK03110
uniprot id: Q5K958
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase U48 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

214684:CNE00450
gene id: 214684:CNE00450
uniprot id: Q5KHD2
names: Subcellular Location Annotation
messages: Nucleus

214684:CNN00410
gene id: 214684:CNN00410
uniprot id: Q5K7B7
names: Function
names: Similarity
messages: Belongs to the TVP38/TMEM64 family.
messages: Golgi membrane protein involved in vesicular trafficking and spindle migration.

214684:CNG01620
gene id: 214684:CNG01620
uniprot id: Q5KE61
names: Function
names: Similarity
messages: Belongs to the BYE1 family.
messages: Negative regulator of transcription elongation.

214684:CNM00640
gene id: 214684:CNM00640
uniprot id: Q5K805
names: Similarity
messages: Belongs to the glycosyl hydrolases 36 family.

214684:CNF04340
gene id: 214684:CNF04340
uniprot id: Q5KET4
names: Subcellular Location Annotation
messages: Membrane

214684:CNG00840
gene id: 214684:CNG00840
uniprot id: Q5KEE0
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

214684:CNC06670
gene id: 214684:CNC06670
uniprot id: Q5KJG0
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

214684:CNA06120
gene id: 214684:CNA06120
uniprot id: Q5KNL0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRA1 family.
messages: Membrane

214684:CNE02080
gene id: 214684:CNE02080
uniprot id: Q5KGW7
names: Similarity
messages: Belongs to the STEEP1 family.

214684:CNF01720
gene id: 214684:CNF01720
uniprot id: Q5KFH6
names: Function
names: Similarity
messages: Belongs to the TVP38/TMEM64 family.
messages: Golgi membrane protein involved in vesicular trafficking and spindle migration.

214684:CNA03810
gene id: 214684:CNA03810
uniprot id: P0CN82
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.

214684:CNK01310
gene id: 214684:CNK01310
uniprot id: Q5K9N9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ORC2 family.
messages: Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication.
messages: Component of the origin recognition complex (ORC).
messages: Nucleus

214684:CNH00130
gene id: 214684:CNH00130
uniprot id: Q5KC85
names: Similarity
messages: Belongs to the ELP6 family.

214684:CNL05820
gene id: 214684:CNL05820
uniprot id: Q5K8G1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferredoxin--NADP reductase type 1 family.
messages: Mitochondrion

214684:CNA05200
gene id: 214684:CNA05200
uniprot id: Q5KNV3
names: Similarity
messages: Belongs to the carnitine/choline acetyltransferase family.

214684:CNG01070
gene id: 214684:CNG01070
uniprot id: Q5KEB6
names: Subcellular Location Annotation
messages: Membrane

214684:CNC00780
gene id: 214684:CNC00780
uniprot id: Q5KL48
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone deacetylase family. HD type 2 subfamily.
messages: Nucleus
messages: Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.

214684:CNB04790
gene id: 214684:CNB04790
uniprot id: Q5KLM0
names: Similarity
messages: Belongs to the MAPRE family.

214684:CNN00430
gene id: 214684:CNN00430
uniprot id: Q5K7B5
names: Similarity
messages: Belongs to the phosphohexose mutase family.

214684:CNC01430
gene id: 214684:CNC01430
uniprot id: P0CS46
names: Function
names: Subcellular Location Annotation
messages: Nucleus
messages: Required for 3'-end cleavage and polyadenylation of pre-mRNAs. Also involved in chromosome segregation where it has a role in chromosome attachment to the mitotic spindle (By similarity).

214684:CNK00060
gene id: 214684:CNK00060
uniprot id: Q5KA05
names: Similarity
messages: Belongs to the glycosyl hydrolase 32 family.

214684:CNB04240
gene id: 214684:CNB04240
uniprot id: Q5KLS4
names: Similarity
messages: Belongs to the WrbA family.

214684:CNI00880
gene id: 214684:CNI00880
uniprot id: Q5KBZ2
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

214684:CNE01910
gene id: 214684:CNE01910
uniprot id: Q5KGY5
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS25 family.

214684:CND02450
gene id: 214684:CND02450
uniprot id: Q5KIM3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 1 lipoyl cofactor covalently.
messages: Mitochondrion
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).

214684:CNB05710
gene id: 214684:CNB05710
uniprot id: Q5KLD0
names: Subcellular Location Annotation
messages: Membrane

214684:CNH02570
gene id: 214684:CNH02570
uniprot id: Q5KCX7
names: Subcellular Location Annotation
messages: Membrane

214684:CNL03940
gene id: 214684:CNL03940
uniprot id: P0CR90
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TIM54 family.
messages: Component of the TIM22 complex, whose core is composed of TIM22 and TIM54, associated with the 70 kDa heterohexamer composed of TIM9 and TIM10 (or TIM8 and TIM13).
messages: Essential component of the TIM22 complex, a complex that mediates the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane. The TIM22 complex forms a twin-pore translocase that uses the membrane potential as external driving force (By similarity).
messages: Mitochondrion inner membrane

214684:CNH02290
gene id: 214684:CNH02290
uniprot id: P0CM14
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aldolase class II family. MtnB subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P).
messages: Cytoplasm

214684:CNB04290
gene id: 214684:CNB04290
uniprot id: Q5KLR9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the THOC2 family.
messages: Nucleus

214684:CNM00220
gene id: 214684:CNM00220
uniprot id: Q5K840
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

214684:CNE04480
gene id: 214684:CNE04480
uniprot id: Q5KG86
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sphingosine N-acyltransferase family.
messages: Membrane

214684:CNL06300
gene id: 214684:CNL06300
uniprot id: P0CP06
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NAC-alpha family.
messages: Component of the nascent polypeptide-associated complex (NAC), a dynamic component of the ribosomal exit tunnel, protecting the emerging polypeptides from interaction with other cytoplasmic proteins to ensure appropriate nascent protein targeting. The NAC complex also promotes mitochondrial protein import by enhancing productive ribosome interactions with the outer mitochondrial membrane and blocks the inappropriate interaction of ribosomes translating non-secretory nascent polypeptides with translocation sites in the membrane of the endoplasmic reticulum. EGD2 may also be involved in transcription regulation (By similarity).
messages: Cytoplasm
messages: Nucleus
messages: Part of the nascent polypeptide-associated complex (NAC), consisting of EGD2 and EGD1. NAC associates with ribosomes via EGD1 (By similarity).

214684:CNB03580
gene id: 214684:CNB03580
uniprot id: Q5KLY8
names: Similarity
messages: Belongs to the IMPACT family.

214684:CNK01240
gene id: 214684:CNK01240
uniprot id: Q5K9P5
names: Similarity
messages: Belongs to the prokaryotic/mitochondrial release factor family.

214684:CNK03080
gene id: 214684:CNK03080
uniprot id: Q5K961
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

214684:CNA02410
gene id: 214684:CNA02410
uniprot id: Q5KPL1
names: Similarity
messages: Belongs to the SKP1 family.

214684:CNN00300
gene id: 214684:CNN00300
uniprot id: Q5K7C9
names: Similarity
messages: Belongs to the 2-oxoadipate dioxygenase/decarboxylase family.

214684:CNM02050
gene id: 214684:CNM02050
uniprot id: P0CR10
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: ATP-binding RNA helicase involved in the biogenesis of 60S ribosomal subunits and is required for the normal formation of 25S and 5.8S rRNAs.
messages: Belongs to the DEAD box helicase family. DDX56/DBP9 subfamily.
messages: The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.
messages: nucleolus

214684:CNM01430
gene id: 214684:CNM01430
uniprot id: Q5K7S5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dUTPase family.
messages: Homotrimer.
messages: Involved in nucleotide metabolism via production of dUMP, the immediate precursor of thymidine nucleotides, and decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

214684:CNB02610
gene id: 214684:CNB02610
uniprot id: Q5KM82
names: Similarity
messages: In the C-terminal section; belongs to the trehalose phosphatase family.
messages: In the N-terminal section; belongs to the glycosyltransferase 20 family.

214684:CNH02400
gene id: 214684:CNH02400
uniprot id: Q5KCV9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenylate kinase family. AK6 subfamily.
messages: Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates. Has also ATPase activity. May be involved in rRNA maturation and transcription regulation.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

214684:CNI00700
gene id: 214684:CNI00700
uniprot id: Q5KC10
names: Similarity
messages: Belongs to the MT-A70-like family.

214684:CNG03100
gene id: 214684:CNG03100
uniprot id: Q5KDR0
names: Similarity
names: Subunit
messages: Belongs to the LDH/MDH superfamily. MDH type 1 family.
messages: Homodimer.

214684:CNH03630
gene id: 214684:CNH03630
uniprot id: Q5KD82
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFS5 subunit family.
messages: Membrane
messages: Mitochondrion inner membrane

214684:CNG00850
gene id: 214684:CNG00850
uniprot id: Q5KED8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YIP1 family.
messages: Golgi apparatus membrane
messages: Membrane

214684:CNL04740
gene id: 214684:CNL04740
uniprot id: Q5K8R7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ubiA prenyltransferase family.
messages: Converts protoheme IX and farnesyl diphosphate to heme O.
messages: Membrane
messages: Mitochondrion membrane

214684:CNA07790
gene id: 214684:CNA07790
uniprot id: Q5KN43
names: Similarity
messages: Belongs to the RCAN family.

214684:CNJ01770
gene id: 214684:CNJ01770
uniprot id: Q5KAG6
names: Subcellular Location Annotation
messages: Membrane

214684:CNN01010
gene id: 214684:CNN01010
uniprot id: Q5K758
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

214684:CNF00970
gene id: 214684:CNF00970
uniprot id: Q5KFQ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c-type heme lyase family.
messages: Lyase that catalyzes the covalent linking of the heme group to the cytochrome C apoprotein to produce the mature functional cytochrome.
messages: Membrane
messages: Mitochondrion inner membrane

214684:CNJ00880
gene id: 214684:CNJ00880
uniprot id: P0CM04
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the actin family. ARP6 subfamily.
messages: Component of the SWR1 chromatin remodeling complex.
messages: Component of the SWR1 complex which mediates the ATP-dependent exchange of histone H2A for the H2A variant HZT1 leading to transcriptional regulation of selected genes by chromatin remodeling. Involved in chromosome stability (By similarity).
messages: Cytoplasm
messages: Nucleus
messages: cytoskeleton

214684:CNJ01990
gene id: 214684:CNJ01990
uniprot id: Q5KAE4
names: Similarity
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase NEP1 family.

214684:CNI00190
gene id: 214684:CNI00190
uniprot id: Q5KC54
names: Similarity
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.

214684:CNA05400
gene id: 214684:CNA05400
uniprot id: Q5KNT2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the snRNP Sm proteins family.
messages: LSm subunits form a heteromer with a doughnut shape.
messages: Nucleus
messages: Plays role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex). The heptameric LSM2-8 complex binds specifically to the 3'-terminal U-tract of U6 snRNA.

214684:CND05250
gene id: 214684:CND05250
uniprot id: Q5KHU7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adaptor complexes medium subunit family. Delta-COP subfamily.
messages: COPI-coated vesicle membrane
messages: Cytoplasm
messages: Golgi apparatus membrane
messages: Oligomeric complex that consists of at least the alpha, beta, beta', gamma, delta, epsilon and zeta subunits.
messages: The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.

214684:CNH02360
gene id: 214684:CNH02360
uniprot id: Q5KCV5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WHI5/NRM1 family.
messages: Cytoplasm
messages: Nucleus

214684:CND02330
gene id: 214684:CND02330
uniprot id: Q5KIN5
names: Domain
names: Function
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.
messages: Catalytic subunit in the complex catalyzing the transfer of N-acetylglucosamine from UDP-N-acetylglucosamine to phosphatidylinositol, the first step of GPI biosynthesis.
messages: The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate.

214684:CNE05150
gene id: 214684:CNE05150
uniprot id: Q5KG21
names: Domain
names: Function
names: Similarity
messages: Belongs to the DEAD box helicase family.
messages: RNA helicase.
messages: The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.

214684:CNF01000
gene id: 214684:CNF01000
uniprot id: Q5KFP9
names: Similarity
messages: Belongs to the peptidase A1 family.

214684:CND00750
gene id: 214684:CND00750
uniprot id: Q5KJ40
names: Similarity
messages: Belongs to the peptidase M24 family.

214684:CNH03660
gene id: 214684:CNH03660
uniprot id: Q5K924
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

214684:CNB01800
gene id: 214684:CNB01800
uniprot id: P0CP94
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. FKBP1 subfamily.
messages: Cytoplasm
messages: Inhibited by both FK506 and rapamycin.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides (By similarity).

214684:CNB04020
gene id: 214684:CNB04020
uniprot id: Q5KLU8
names: Subcellular Location Annotation
messages: Membrane

214684:CNN01050
gene id: 214684:CNN01050
uniprot id: Q5K754
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA cytidine acetyltransferase family. NAT10 subfamily.
messages: Interacts with TAN1.
messages: RNA cytidine acetyltransferase with specificity toward both 18S rRNA and tRNAs. Catalyzes the formation of N(4)-acetylcytidine (ac4C) in 18S rRNA. Required for early nucleolar cleavages of precursor rRNA at sites A0, A1 and A2 during 18S rRNA synthesis. Catalyzes the formation of ac4C in serine and leucine tRNAs. Requires the tRNA-binding adapter protein TAN1 for full tRNA acetyltransferase activity but not for 18S rRNA acetylation.
messages: nucleolus

214684:CNG00480
gene id: 214684:CNG00480
uniprot id: Q5KEH7
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Golgi apparatus membrane
messages: Membrane
messages: Oligomeric complex that consists of at least the alpha, beta, beta', gamma, delta, epsilon and zeta subunits.
messages: The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network.

214684:CNN01390
gene id: 214684:CNN01390
uniprot id: P0CM70
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COX23 family.
messages: Mitochondrion intermembrane space
messages: Required for the assembly of cytochrome c oxidase.

214684:CNN01730
gene id: 214684:CNN01730
uniprot id: Q5K6Y9
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

214684:CNJ02420
gene id: 214684:CNJ02420
uniprot id: Q5KAA3
names: Similarity
messages: Belongs to the BolA/IbaG family.

214684:CNH00170
gene id: 214684:CNH00170
uniprot id: Q5KC89
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic PMM family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the synthesis of the GDP-mannose and dolichol-phosphate-mannose required for a number of critical mannosyl transfer reactions.

214684:CNE02630
gene id: 214684:CNE02630
uniprot id: Q5KGR4
names: Similarity
messages: Belongs to the glycosyl hydrolase 15 family.

214684:CNH03730
gene id: 214684:CNH03730
uniprot id: Q5K918
names: Similarity
messages: Belongs to the GMC oxidoreductase family.

214684:CNL04310
gene id: 214684:CNL04310
uniprot id: Q5K8W0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

214684:CNB03790
gene id: 214684:CNB03790
uniprot id: Q5KLW7
names: Similarity
messages: Belongs to the chaperonin (HSP60) family.

214684:CNK03450
gene id: 214684:CNK03450
uniprot id: Q5K928
names: Subcellular Location Annotation
messages: Membrane

214684:CNG03030
gene id: 214684:CNG03030
uniprot id: Q5KDR7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

214684:CNK02070
gene id: 214684:CNK02070
uniprot id: P0CS44
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat MDV1/CAF4 family.
messages: Involved in mitochondrial fission. Acts as an adapter protein required to form mitochondrial fission complexes. Formation of these complexes is required to promote constriction and fission of the mitochondrial compartment at a late step in mitochondrial division (By similarity).
messages: Mitochondrion outer membrane

214684:CNM01710
gene id: 214684:CNM01710
uniprot id: Q5K7P7
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

214684:CNB02050
gene id: 214684:CNB02050
uniprot id: Q5KMD8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SRP72 family.
messages: Cytoplasm

214684:CNB04270
gene id: 214684:CNB04270
uniprot id: Q5KLS1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat ELP2 family.
messages: Cytoplasm
messages: Nucleus

214684:CNH02010
gene id: 214684:CNH02010
uniprot id: Q5KCR8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNF2/RAD54 helicase family. ISWI subfamily.
messages: Nucleus

214684:CNC00540
gene id: 214684:CNC00540
uniprot id: Q5KL71
names: Similarity
messages: Belongs to the HARBI1 family.

214684:CNA06790
gene id: 214684:CNA06790
uniprot id: Q5KNE3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PurH family.
messages: cytosol

214684:CND02290
gene id: 214684:CND02290
uniprot id: Q5KIN9
names: Similarity
messages: Belongs to the SF3A2 family.

214684:CNE05220
gene id: 214684:CNE05220
uniprot id: Q5KG14
names: Similarity
messages: Belongs to the TMA16 family.

214684:CND04270
gene id: 214684:CND04270
uniprot id: Q5KI44
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BCAP29/BCAP31 family.
messages: Endoplasmic reticulum membrane
messages: May play a role in anterograde transport of membrane proteins from the endoplasmic reticulum to the Golgi.
messages: Membrane

214684:CNA03160
gene id: 214684:CNA03160
uniprot id: Q5KPD7
names: Similarity
messages: Belongs to the heat shock protein 70 family.

214684:CNC00580
gene id: 214684:CNC00580
uniprot id: Q5KL67
names: Function
names: Similarity
messages: Belongs to the PIGL family.
messages: Involved in the second step of GPI biosynthesis. De-N-acetylation of N-acetylglucosaminyl-phosphatidylinositol.

214684:CNE01710
gene id: 214684:CNE01710
uniprot id: Q5KH04
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic ribosomal protein eL8 family.
messages: Common component of the spliceosome and rRNA processing machinery.
messages: nucleolus

214684:CNC02510
gene id: 214684:CNC02510
uniprot id: Q5KKM5
names: Similarity
messages: Belongs to the glycosyl hydrolase 3 family.

214684:CNI01000
gene id: 214684:CNI01000
uniprot id: Q5KBY0
names: Similarity
messages: Belongs to the DNA2/NAM7 helicase family.

214684:CND00900
gene id: 214684:CND00900
uniprot id: Q5KJ25
names: Subcellular Location Annotation
messages: Nucleus

214684:CND04910
gene id: 214684:CND04910
uniprot id: Q5KHY1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48A family.
messages: Binds 1 zinc ion per subunit.
messages: Endoplasmic reticulum membrane
messages: Proteolytically removes the C-terminal three residues of farnesylated proteins.

214684:CNL06680
gene id: 214684:CNL06680
uniprot id: Q5K875
names: Subcellular Location Annotation
messages: Membrane

214684:CNL06080
gene id: 214684:CNL06080
uniprot id: Q5K8D6
names: Similarity
messages: Belongs to the eIF-2B alpha/beta/delta subunits family.

214684:CNI01900
gene id: 214684:CNI01900
uniprot id: Q5KBP2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TRM5/TYW2 family.
messages: Cytoplasm
messages: Mitochondrion matrix
messages: Monomer.
messages: Nucleus
messages: Specifically methylates the N1 position of guanosine-37 in various cytoplasmic and mitochondrial tRNAs. Methylation is not dependent on the nature of the nucleoside 5' of the target nucleoside. This is the first step in the biosynthesis of wybutosine (yW), a modified base adjacent to the anticodon of tRNAs and required for accurate decoding.

214684:CNA07660
gene id: 214684:CNA07660
uniprot id: Q5KN56
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PA-phosphatase related phosphoesterase family.
messages: Membrane

214684:CNC00420
gene id: 214684:CNC00420
uniprot id: Q5KL82
names: Similarity
messages: Belongs to the methyltransferase superfamily. HEN1 family.

214684:CNB05450
gene id: 214684:CNB05450
uniprot id: Q5KLF5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat NOL10/ENP2 family.
messages: nucleolus

214684:CNH01030
gene id: 214684:CNH01030
uniprot id: Q5KCH4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFA2 subunit family.
messages: Mitochondrion inner membrane

214684:CND01900
gene id: 214684:CND01900
uniprot id: Q5KIS7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

214684:CNM00360
gene id: 214684:CNM00360
uniprot id: Q5K826
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.
messages: In eukaryotes there are cytoplasmic, mitochondrial and chloroplastic isozymes.

214684:CNJ02600
gene id: 214684:CNJ02600
uniprot id: Q5KA86
names: Similarity
messages: Belongs to the DapA family.

214684:CNA05380
gene id: 214684:CNA05380
uniprot id: Q5KNT5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the wax synthase family.
messages: Membrane

214684:CNG01450
gene id: 214684:CNG01450
uniprot id: Q5KE78
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

214684:CNJ00950
gene id: 214684:CNJ00950
uniprot id: Q5KAP7
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) per subunit.

214684:CNB00910
gene id: 214684:CNB00910
uniprot id: Q5KMQ1
names: Similarity
messages: Belongs to the UPF0057 (PMP3) family.

214684:CNI02550
gene id: 214684:CNI02550
uniprot id: Q5KBH1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VPS41 family.
messages: Required for vacuolar assembly and vacuolar traffic.
messages: Vacuole

214684:CNC03050
gene id: 214684:CNC03050
uniprot id: Q5KKG9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTP-binding SRP family.
messages: Endoplasmic reticulum membrane
messages: Membrane

214684:CNC06600
gene id: 214684:CNC06600
uniprot id: Q5KJG7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Mitochondrion matrix

214684:CNB04400
gene id: 214684:CNB04400
uniprot id: Q5KLQ9
names: Subcellular Location Annotation
messages: Membrane

214684:CNC04720
gene id: 214684:CNC04720
uniprot id: Q5KK05
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SWP1 family.
messages: Component of the oligosaccharyltransferase (OST) complex.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All subunits are required for a maximal enzyme activity.

214684:CND00020
gene id: 214684:CND00020
uniprot id: Q5KJA6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

214684:CNA08320
gene id: 214684:CNA08320
uniprot id: Q5KMZ3
names: Subcellular Location Annotation
messages: Membrane

214684:CNA00030
gene id: 214684:CNA00030
uniprot id: Q5KQ98
names: Subcellular Location Annotation
messages: Membrane

214684:CNA00990
gene id: 214684:CNA00990
uniprot id: P0CR26
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvB family.
messages: DNA helicase which participates in several chromatin remodeling complexes, including the SWR1 and the INO80 complexes. The SWR1 complex mediates the ATP-dependent exchange of histone H2A for the H2A variant HZT1 leading to transcriptional regulation of selected genes by chromatin remodeling. The INO80 complex remodels chromatin by shifting nucleosomes and is involved in DNA repair. Also involved in pre-rRNA processing (By similarity).
messages: May form heterododecamers with RVB2. Component of the SWR1 chromatin remodeling complex, the INO80 chromatin remodeling complex, and of the R2TP complex (By similarity).
messages: Nucleus

214684:CNE01880
gene id: 214684:CNE01880
uniprot id: Q5KGY8
names: Subcellular Location Annotation
messages: Membrane

214684:CNF00330
gene id: 214684:CNF00330
uniprot id: Q5KFW5
uniprot id: Q5KFW7
names: Subcellular Location Annotation
messages: Membrane

214684:CNB04480
gene id: 214684:CNB04480
uniprot id: Q5KLQ1
names: Similarity
messages: Belongs to the peptidase M20A family.

214684:CNE03370
gene id: 214684:CNE03370
uniprot id: Q5KGJ7
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

214684:CNM02180
gene id: 214684:CNM02180
uniprot id: Q5K7J8
names: Similarity
messages: Belongs to the amidase family.

214684:CNE04410
gene id: 214684:CNE04410
uniprot id: Q5KG94
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ARPC2 family.
messages: Component of the Arp2/3 complex.
messages: Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.
messages: cytoskeleton

214684:CNH01590
gene id: 214684:CNH01590
uniprot id: P0CQ02
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PTPA-type PPIase family.
messages: Cytoplasm
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. Acts as a regulatory subunit for PP2A-like phosphatases modulating their activity or substrate specificity, probably by inducing a conformational change in the catalytic subunit, a direct target of the PPIase. Can reactivate inactive phosphatase PP2A-phosphatase methylesterase complexes (PP2Ai) in presence of ATP and Mg(2+) by dissociating the inactive form from the complex (By similarity).

214684:CND04460
gene id: 214684:CND04460
uniprot id: Q5KI25
names: Subcellular Location Annotation
messages: nuclear pore complex

214684:CNA02500
gene id: 214684:CNA02500
uniprot id: Q5KDY8
names: Similarity
messages: Belongs to the HARBI1 family.

214684:CND02930
gene id: 214684:CND02930
uniprot id: Q5KIH7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SMC family. SMC3 subfamily.
messages: Nucleus

214684:CNC04150
gene id: 214684:CNC04150
uniprot id: Q5KK60
names: Cofactor
names: Similarity
messages: Belongs to the class-II DAHP synthase family.
messages: Binds 1 divalent cation per subunit. The enzyme is active with manganese, cobalt or cadmium ions.

214684:CNB00270
gene id: 214684:CNB00270
uniprot id: Q5KMW4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat SEC13 family.
messages: nuclear pore complex

214684:CNG02690
gene id: 214684:CNG02690
uniprot id: P0CM94
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associates with the NTC complex (or PRP19-associated complex). The NTC complex associates with the spliceosome after the release of the U1 and U4 snRNAs and forms the CWC spliceosome subcomplex reminiscent of a late-stage spliceosome.
messages: Belongs to the CWC21 family.
messages: Cytoplasm
messages: Involved in pre-mRNA splicing. May function at or prior to the first catalytic step of splicing at the catalytic center of the spliceosome. May do so by stabilizing the catalytic center or the position of the RNA substrate (By similarity).
messages: Nucleus

214684:CNA01120
gene id: 214684:CNA01120
uniprot id: Q5KPY6
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

214684:CNA01890
gene id: 214684:CNA01890
uniprot id: Q5KPQ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Su(H) family.
messages: Nucleus

214684:CNN01770
gene id: 214684:CNN01770
uniprot id: Q5K6Y4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TspO/BZRP family.
messages: Membrane

214684:CNI00900
gene id: 214684:CNI00900
uniprot id: Q5KBZ0
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

214684:CNF00860
gene id: 214684:CNF00860
uniprot id: Q5KFR3
names: Similarity
messages: Belongs to the PRP18 family.

214684:CND02950
gene id: 214684:CND02950
uniprot id: Q5KIH5
names: Similarity
messages: Belongs to the peptidase M18 family.

214684:CND05640
gene id: 214684:CND05640
uniprot id: Q5KHQ8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. NOG2 subfamily.
messages: GTPase that associates with pre-60S ribosomal subunits in the nucleolus and is required for their nuclear export and maturation.
messages: nucleolus

214684:CNJ01030
gene id: 214684:CNJ01030
uniprot id: Q5KAN9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAM41 family.
messages: Mitochondrion inner membrane

214684:CNG02770
gene id: 214684:CNG02770
uniprot id: Q5KDU3
names: Similarity
messages: Belongs to the RRP1 family.

214684:CNF00780
gene id: 214684:CNF00780
uniprot id: P0CM62
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CFT1 family.
messages: Nucleus
messages: RNA-binding component of the cleavage and polyadenylation factor (CPF) complex, which plays a key role in polyadenylation-dependent pre-mRNA 3'-end formation and cooperates with cleavage factors including the CFIA complex and NAB4/CFIB. Involved in poly(A) site recognition. May be involved in coupling transcription termination and mRNA 3'-end formation (By similarity).

214684:CNK02950
gene id: 214684:CNK02950
uniprot id: Q5K974
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase T1B family.
messages: Cytoplasm
messages: Non-catalytic component of the proteasome.
messages: Nucleus

214684:CNJ00160
gene id: 214684:CNJ00160
uniprot id: Q5KAX2
names: Similarity
messages: Belongs to the cyclin family.

214684:CNM01670
gene id: 214684:CNM01670
uniprot id: Q5K7Q1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent DNA helicase involved in DNA damage repair by homologous recombination and in genome maintenance. Capable of unwinding D-loops. Plays a role in limiting crossover recombinants during mitotic DNA double-strand break (DSB) repair. Component of a FANCM-MHF complex which promotes gene conversion at blocked replication forks, probably by reversal of the stalled fork.
messages: Belongs to the DEAD box helicase family. DEAH subfamily. FANCM sub-subfamily.
messages: Interacts with the MHF histone-fold complex to form the FANCM-MHF complex.
messages: Nucleus

214684:CNK01830
gene id: 214684:CNK01830
uniprot id: Q5K9I3
names: Similarity
messages: Belongs to the actin family.

214684:CNE00750
gene id: 214684:CNE00750
uniprot id: Q5KHA1
names: Similarity
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.

214684:CND02510
gene id: 214684:CND02510
uniprot id: Q5KIL7
names: Function
names: Similarity
messages: Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.
messages: Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl-glutathione to form glutathione and D-lactic acid.

214684:CND05840
gene id: 214684:CND05840
uniprot id: Q5KHN7
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

214684:CNB04510
gene id: 214684:CNB04510
uniprot id: Q5KLP9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as component of the MCM2-7 complex (MCM complex) which is the replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity.
messages: Belongs to the MCM family.
messages: Component of the MCM2-7 complex.
messages: Nucleus

214684:CNC06220
gene id: 214684:CNC06220
uniprot id: Q5KJK5
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

214684:CND04570
gene id: 214684:CND04570
uniprot id: Q5KI13
names: Subcellular Location Annotation
messages: Nucleus

214684:CNJ01050
gene id: 214684:CNJ01050
uniprot id: Q5KAN7
names: Subcellular Location Annotation
messages: Membrane

214684:CNE00970
gene id: 214684:CNE00970
uniprot id: Q5KH77
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SMC family.
messages: Nucleus

214684:CNG02890
gene id: 214684:CNG02890
uniprot id: Q5KDT0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EMP24/GP25L family.
messages: Membrane

214684:CNH02280
gene id: 214684:CNH02280
uniprot id: Q5KCU5
names: Similarity
messages: Belongs to the glycosyltransferase 2 family.

214684:CNG01480
gene id: 214684:CNG01480
uniprot id: Q5KE75
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

214684:CND05120
gene id: 214684:CND05120
uniprot id: Q5KHW1
names: Similarity
messages: Belongs to the class-I DAHP synthase family.

214684:CNC05840
gene id: 214684:CNC05840
uniprot id: Q5KJP1
names: Similarity
messages: Belongs to the glycosyltransferase 32 family.

214684:CNK00070
gene id: 214684:CNK00070
uniprot id: Q5KA04
names: Similarity
messages: Belongs to the XFP family.

214684:CNF00480
gene id: 214684:CNF00480
uniprot id: Q5KFV0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP11 family.
messages: Mitochondrion

214684:CNC06000
gene id: 214684:CNC06000
uniprot id: Q5KJM5
names: Similarity
messages: Belongs to the alpha-actinin family.

214684:CNE04320
gene id: 214684:CNE04320
uniprot id: P0CR44
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SFH5 family.
messages: Cytoplasm
messages: Endoplasmic reticulum membrane
messages: Microsome membrane
messages: Non-classical phosphatidylinositol (PtdIns) transfer protein (PITP), which exhibits PtdIns-binding/transfer activity in the absence of detectable PtdCho-binding/transfer activity. Regulates PtdIns(4,5)P2 homeostasis at the plasma membrane. Heme-binding protein that may play a role in organic oxidant-induced stress responses.

214684:CND03140
gene id: 214684:CND03140
uniprot id: Q5KIF6
names: Function
names: Similarity
messages: Belongs to the RNA polymerase beta' chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.

214684:CNC02250
gene id: 214684:CNC02250
uniprot id: Q5KKQ0
names: Similarity
messages: Belongs to the HMBS family.

214684:CNC00680
gene id: 214684:CNC00680
uniprot id: Q5KL58
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TFIIF alpha subunit family.
messages: Nucleus
messages: TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation.

214684:CNA01710
gene id: 214684:CNA01710
uniprot id: Q5KPS5
names: Similarity
messages: Belongs to the VPS29 family.

214684:CND00240
gene id: 214684:CND00240
uniprot id: Q5KJ87
names: Cofactor
names: Similarity
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.

214684:CNC02850
gene id: 214684:CNC02850
uniprot id: Q5KKI9
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

214684:CNC00960
gene id: 214684:CNC00960
uniprot id: P0CR54
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A component of the endosomal sorting required for transport complex III (ESCRT-III).
messages: Belongs to the SNF7 family.
messages: Cytoplasm
messages: Endosome membrane
messages: Required for the sorting and concentration of proteins resulting in the entry of these proteins into the invaginating vesicles of the multivesicular body (MVB). Also required for the proteolytic cleavage of the transcription factor RIM101 in response to alkaline ambient pH (By similarity).

214684:CNM01550
gene id: 214684:CNM01550
uniprot id: Q5K7R3
names: Similarity
messages: Belongs to the AAA ATPase family.

214684:CNI03760
gene id: 214684:CNI03760
uniprot id: Q5KB51
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mL43 family.
messages: Mitochondrion

214684:CNH01040
gene id: 214684:CNH01040
uniprot id: P0CP08
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NAC-beta family.
messages: Component of the nascent polypeptide-associated complex (NAC), a dynamic component of the ribosomal exit tunnel, protecting the emerging polypeptides from interaction with other cytoplasmic proteins to ensure appropriate nascent protein targeting. The NAC complex also promotes mitochondrial protein import by enhancing productive ribosome interactions with the outer mitochondrial membrane and blocks the inappropriate interaction of ribosomes translating non-secretory nascent polypeptides with translocation sites in the membrane of the endoplasmic reticulum. EGD1 may act as a transcription factor that exert a negative effect on the expression of several genes that are transcribed by RNA polymerase II.
messages: Cytoplasm
messages: Nucleus
messages: Part of the nascent polypeptide-associated complex (NAC), consisting of EGD2 and EGD1. NAC associates with ribosomes via EGD1 (By similarity).

214684:CNB00250
gene id: 214684:CNB00250
uniprot id: P0CS80
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
messages: Forms a complex with TRM82.
messages: Nucleus

214684:CNH00290
gene id: 214684:CNH00290
uniprot id: Q5KCA0
names: Similarity
messages: Belongs to the protein kinase superfamily.

214684:CND00530
gene id: 214684:CND00530
uniprot id: Q5KJ61
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

214684:CNG04200
gene id: 214684:CNG04200
uniprot id: Q5KDF2
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

214684:CNC07020
gene id: 214684:CNC07020
uniprot id: Q5KJC6
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.

214684:CNM02490
gene id: 214684:CNM02490
uniprot id: P0CR86
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CLU family.
messages: Cytoplasm
messages: May associate with the eukaryotic translation initiation factor 3 (eIF-3) complex.
messages: mRNA-binding protein involved in proper cytoplasmic distribution of mitochondria.

214684:CNI03160
gene id: 214684:CNI03160
uniprot id: Q5KBB1
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.

214684:CNG02260
gene id: 214684:CNG02260
uniprot id: Q5KDZ6
names: Similarity
messages: Belongs to the BolA/IbaG family.

214684:CNJ03270
gene id: 214684:CNJ03270
uniprot id: Q5KA29
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the clathrin heavy chain family.
messages: Clathrin is the major protein of the polyhedral coat of coated pits and vesicles.
messages: Cytoplasmic vesicle membrane
messages: Membrane
messages: coated pit

214684:CNF02080
gene id: 214684:CNF02080
uniprot id: Q5KFD9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1B family.
messages: Component of the proteasome complex.
messages: Component of the proteasome, a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.
messages: Cytoplasm
messages: Nucleus
messages: The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits. The 20S proteasome core is composed of 28 subunits that are arranged in four stacked rings, resulting in a barrel-shaped structure. The two end rings are each formed by seven alpha subunits, and the two central rings are each formed by seven beta subunits. The catalytic chamber with the active sites is on the inside of the barrel.

214684:CNN00440
gene id: 214684:CNN00440
uniprot id: Q5K7B4
names: Function
names: Similarity
messages: Catalyzes the second and fifth step in the 'de novo' purine biosynthesis pathway; contains phosphoribosylamine--glycine ligase (GARS) and phosphoribosylformylglycinamidine cyclo-ligase (AIRS) activities.
messages: In the C-terminal section; belongs to the AIR synthase family.
messages: In the N-terminal section; belongs to the GARS family.

214684:CNF02310
gene id: 214684:CNF02310
uniprot id: Q5KFB6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VTA1 family.
messages: Cytoplasm
messages: Endosome membrane
messages: Membrane

214684:CNI02470
gene id: 214684:CNI02470
uniprot id: P0CQ62
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BRE1 family.
messages: E3 ubiquitin-protein ligase that mediates monoubiquitination of histone H2B to form H2BK123ub1. H2BK123ub1 gives a specific tag for epigenetic transcriptional activation and is also a prerequisite for H3K4me and H3K79me formation.
messages: Nucleus

214684:CNA04300
gene id: 214684:CNA04300
uniprot id: Q5KP38
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NOB1 family.
messages: Required for the synthesis of 40S ribosome subunits. Has a role in processing 20S pre-rRNA into the mature 18S rRNA, where it is required for cleavage at the 3' end of the mature 18S rRNA (D-site). Accompanies the 20S pre-rRNA from the nucleus to the cytoplasm.
messages: nucleolus

214684:CNL06000
gene id: 214684:CNL06000
uniprot id: Q5K8E4
names: Subcellular Location Annotation
messages: Membrane

214684:CNB00890
gene id: 214684:CNB00890
uniprot id: P0CN72
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EMP24/GP25L family.
messages: Constituent of COPII-coated endoplasmic reticulum-derived transport vesicles. Required for efficient transport of a subset of secretory proteins to the Golgi. Facilitates retrograde transport from the Golgi to the endoplasmic reticulum (By similarity).
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane

214684:CNH03760
gene id: 214684:CNH03760
uniprot id: P0CP32
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleotide-sugar transporter family. SLC35B subfamily.
messages: Endoplasmic reticulum membrane
messages: May be involved in specific transport of UDP-Gal from the cytosol to the Golgi lumen. Involved in the maintenance of optimal conditions for the folding of secretory pathway proteins in the endoplasmic reticulum (By similarity).
messages: There are two genes coding for HUT1 in strain JEC21, due to a translocation and segmental duplication on chromosomes 8 and 12.

214684:CNA05940
gene id: 214684:CNA05940
uniprot id: Q5KNM9
names: Similarity
messages: Belongs to the helicase family. RAD25/XPB subfamily.

214684:CNA00340
gene id: 214684:CNA00340
uniprot id: Q5KQ61
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the proteasome inhibitor PI31 family.
messages: Cytoplasm
messages: Endoplasmic reticulum
messages: Plays an important role in control of proteasome function. Inhibits the hydrolysis of protein and peptide substrates by the 20S proteasome. Also inhibits the activation of the proteasome by the proteasome regulatory proteins PA700 and PA28.

214684:CNF04700
gene id: 214684:CNF04700
uniprot id: Q5KEP9
names: Similarity
messages: Belongs to the CBF/MAK21 family.

214684:CNN00480
gene id: 214684:CNN00480
uniprot id: P0CS54
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the WD repeat WDR12/YTM1 family.
messages: Component of the NOP7 complex, composed of ERB1, NOP7 and YTM1. The complex is held together by ERB1, which interacts with NOP7 via its N-terminal domain and with YTM1 via a high-affinity interaction between the seven-bladed beta-propeller domains of the 2 proteins. The NOP7 complex associates with the 66S pre-ribosome. Interacts (via UBL domain) with MDN1 (via VWFA/MIDAS domain).
messages: Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome.
messages: nucleolus
messages: nucleoplasm

214684:CNL06350
gene id: 214684:CNL06350
uniprot id: Q5K8A9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the snRNP Sm proteins family.
messages: Component of the cytoplasmic LSM1-LSM7 complex which is involved in mRNA degradation.
messages: Component of the heptameric LSM1-LSM7 complex that forms a seven-membered ring structure with a donut shape.
messages: Cytoplasm
messages: P-body

214684:CNC03220
gene id: 214684:CNC03220
uniprot id: Q5KKF1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

214684:CNA03790
gene id: 214684:CNA03790
uniprot id: Q5KP89
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily.

214684:CNM02410
gene id: 214684:CNM02410
uniprot id: Q5K7H6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein disulfide isomerase family.
messages: Endoplasmic reticulum lumen
messages: Participates in the folding of proteins containing disulfide bonds, may be involved in glycosylation, prolyl hydroxylation and triglyceride transfer.

214684:CNF04450
gene id: 214684:CNF04450
uniprot id: Q5KES4
names: Function
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).

214684:CNG01600
gene id: 214684:CNG01600
uniprot id: P0CS04
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TPT transporter family. SLC35D subfamily.
messages: Cytoplasmic vesicle membrane
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Homooligomer.
messages: Involved in the import of GDP-mannose from the cytoplasm into the Golgi lumen.

214684:CNE03180
gene id: 214684:CNE03180
uniprot id: Q5KGL6
names: Similarity
messages: Belongs to the PPC synthetase family.

214684:CNE01150
gene id: 214684:CNE01150
uniprot id: Q5KH60
names: Subcellular Location Annotation
messages: Mitochondrion inner membrane

214684:CNC06840
gene id: 214684:CNC06840
uniprot id: Q5KJE3
names: Similarity
messages: Belongs to the PPP phosphatase family. PP-5 (PP-T) subfamily.

214684:CNI02790
gene id: 214684:CNI02790
uniprot id: Q5KBE8
names: Similarity
messages: Belongs to the peptidase M20A family.

214684:CNA03720
gene id: 214684:CNA03720
uniprot id: Q5KP96
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.
messages: Membrane

214684:CNI00230
gene id: 214684:CNI00230
uniprot id: Q5KC51
names: Similarity
messages: Belongs to the eIF-2-alpha family.

214684:CNM02030
gene id: 214684:CNM02030
uniprot id: Q5K7L4
names: Subcellular Location Annotation
messages: Membrane

214684:CNE03960
gene id: 214684:CNE03960
uniprot id: Q5KGD9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFA12 subunit family.
messages: Mitochondrion inner membrane

214684:CNB00040
gene id: 214684:CNB00040
uniprot id: Q5KMY6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat UTP18 family.
messages: nucleolus

214684:CNA04060
gene id: 214684:CNA04060
uniprot id: Q5KP62
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit. The potassium ion interacts primarily with the substrate.
messages: Binds 2 magnesium ions per subunit. The magnesium ions interact primarily with the substrate.
messages: Catalyzes the formation of S-adenosylmethionine from methionine and ATP.

214684:CNB04560
gene id: 214684:CNB04560
uniprot id: Q5KLP4
names: Subunit
messages: Heterodimer of an alpha and a beta subunit.

214684:CNN00630
gene id: 214684:CNN00630
uniprot id: A0A0S2M672
uniprot id: Q5K796
names: Similarity
messages: Belongs to the activator 1 small subunits family.

214684:CNI00580
gene id: 214684:CNI00580
uniprot id: Q5KC20
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the clathrin light chain family.
messages: Clathrin is the major protein of the polyhedral coat of coated pits and vesicles.
messages: Cytoplasmic vesicle membrane
messages: coated pit

214684:CNA03040
gene id: 214684:CNA03040
uniprot id: Q5KPE9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RER1 family.
messages: Membrane

214684:CNA02570
gene id: 214684:CNA02570
uniprot id: Q5KPJ5
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Mitochondrion

214684:CNL06380
gene id: 214684:CNL06380
uniprot id: Q5K8A6
names: Subcellular Location Annotation
messages: Nucleus

214684:CNL05160
gene id: 214684:CNL05160
uniprot id: P0CN56
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-3 subunit L family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex.
messages: Cytoplasm

214684:CNA03340
gene id: 214684:CNA03340
uniprot id: P0CO74
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 6 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).
messages: Component of the Mediator complex.
messages: Nucleus

214684:CND02920
gene id: 214684:CND02920
uniprot id: Q5KIH8
names: Similarity
messages: Belongs to the UreD family.

214684:CNH00340
gene id: 214684:CNH00340
uniprot id: Q5KCA4
names: Function
names: Similarity
messages: Belongs to the WD repeat EIF2A family.
messages: Functions in the early steps of protein synthesis of a small number of specific mRNAs. Acts by directing the binding of methionyl-tRNAi to 40S ribosomal subunits. In contrast to the eIF-2 complex, it binds methionyl-tRNAi to 40S subunits in a codon-dependent manner, whereas the eIF-2 complex binds methionyl-tRNAi to 40S subunits in a GTP-dependent manner.

214684:CNC04520
gene id: 214684:CNC04520
uniprot id: Q5KK23
names: Function
names: Similarity
messages: Belongs to the eukaryotic/archaeal RNase P protein component 2 family.
messages: Component of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends.

214684:CNB00300
gene id: 214684:CNB00300
uniprot id: Q5KMW2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class II fructose-bisphosphate aldolase family.
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.
messages: Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.

214684:CND06290
gene id: 214684:CND06290
uniprot id: Q5KHJ2
names: Similarity
names: Subunit
messages: Belongs to the AlaDH/PNT family.
messages: Monomer.

214684:CNM01860
gene id: 214684:CNM01860
uniprot id: Q5K7N1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the unc-93 family.
messages: Membrane

214684:CNH00120
gene id: 214684:CNH00120
uniprot id: Q5KC84
names: Function
names: Similarity
messages: Belongs to the peroxiredoxin family. Prx5 subfamily.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

214684:CNE03720
gene id: 214684:CNE03720
uniprot id: Q5KGG3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA polymerase beta' chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Nucleus

214684:CNF04600
gene id: 214684:CNF04600
uniprot id: Q5KEQ9
names: Subcellular Location Annotation
messages: Membrane

214684:CNN00850
gene id: 214684:CNN00850
uniprot id: Q5K774
names: Similarity
messages: Belongs to the HIT family.

214684:CNA08290
gene id: 214684:CNA08290
uniprot id: Q5KMZ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ERG2 family.
messages: Catalyzes the reaction which results in unsaturation at C-7 in the B ring of sterols.
messages: Endoplasmic reticulum membrane

214684:CND02890
gene id: 214684:CND02890
uniprot id: Q5KII1
names: Similarity
messages: Belongs to the SNF2/RAD54 helicase family.

214684:CNE03590
gene id: 214684:CNE03590
uniprot id: Q5KGH5
names: Subcellular Location Annotation
messages: Membrane

214684:CNH01520
gene id: 214684:CNH01520
uniprot id: Q5KCL7
names: Similarity
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily.

214684:CNC03740
gene id: 214684:CNC03740
uniprot id: Q5KKA1
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

214684:CNL04950
gene id: 214684:CNL04950
uniprot id: Q5K8P5
names: Similarity
messages: Belongs to the diphosphomevalonate decarboxylase family.

214684:CNI02480
gene id: 214684:CNI02480
uniprot id: P0CP38
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the nudE family.
messages: Required for nuclear migration.
messages: Self-associates. Interacts with PAC1 (By similarity).
messages: cytoskeleton

214684:CNB02220
gene id: 214684:CNB02220
uniprot id: Q5KMC0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: nucleolus

214684:CNN01260
gene id: 214684:CNN01260
uniprot id: F5HCX1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIIA subfamily.
messages: Cell membrane
messages: The plasma membrane ATPase of plants and fungi is a hydrogen ion pump. The proton gradient it generates drives the active transport of nutrients by H(+)-symport. The resulting external acidification and/or internal alkinization may mediate growth responses.

214684:CNF01970
gene id: 214684:CNF01970
uniprot id: Q5KFF0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as one of several non-catalytic accessory components of the cytoplasmic dynein complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in changing or maintaining the spatial distribution of cytoskeletal structures.
messages: Belongs to the dynein light chain family.
messages: Cytoplasmic dynein consists of two catalytic heavy chains (HCs) and a number of non-catalytic subunits which present intermediate chains (ICs), light intermediate chains (LICs) and light chains (LCs).
messages: cytoskeleton
messages: nuclear pore complex

214684:CNJ03240
gene id: 214684:CNJ03240
uniprot id: P0CS30
names: Function
names: Similarity
messages: Belongs to the WD repeat CIA1 family.
messages: Essential component of the cytosolic iron-sulfur (Fe/S) protein assembly machinery. Required for the maturation of extramitochondrial Fe/S proteins.

214684:CNA08010
gene id: 214684:CNA08010
uniprot id: P0CS16
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ubiquitin-conjugating enzyme family.
messages: Catalyzes the covalent attachment of ubiquitin to other proteins. Plays a role in transcription regulation by catalyzing the monoubiquitination of histone H2B to form H2BK123ub1. H2BK123ub1 gives a specific tag for epigenetic transcriptional activation and is also a prerequisite for H3K4me and H3K79me formation. Also involved in postreplication repair of UV-damaged DNA, in N-end rule-dependent protein degradation and in sporulation.
messages: Cytoplasm
messages: Nucleus

214684:CNC01860
gene id: 214684:CNC01860
uniprot id: Q5KKU0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class II fructose-bisphosphate aldolase family.
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.
messages: Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.

214684:CND05820
gene id: 214684:CND05820
uniprot id: Q5KHN9
names: Function
names: Similarity
messages: Belongs to the phage and mitochondrial RNA polymerase family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.

214684:CNK00360
gene id: 214684:CNK00360
uniprot id: P0CM34
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATG3 family.
messages: Cytoplasm
messages: E2 conjugating enzyme required for the cytoplasm to vacuole transport (Cvt) and autophagy. Required for selective autophagic degradation of the nucleus (nucleophagy) as well as for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production. Responsible for the E2-like covalent binding of phosphatidylethanolamine to the C-terminal Gly of ATG8. The ATG12-ATG5 conjugate plays a role of an E3 and promotes the transfer of ATG8 from ATG3 to phosphatidylethanolamine (PE). This step is required for the membrane association of ATG8. The formation of the ATG8-phosphatidylethanolamine conjugate is essential for autophagy and for the cytoplasm to vacuole transport (Cvt). The ATG8-PE conjugate mediates tethering between adjacent membranes and stimulates membrane hemifusion, leading to expansion of the autophagosomal membrane during autophagy (By similarity).
messages: Monomer. Interacts with ATG8 through an intermediate thioester bond through the C-terminal Gly of ATG8. Also interacts with the 40 amino acid C-terminal region of the E1-like ATG7 enzyme. Interacts also with the ATG12-ATG5 conjugate.
messages: The N-terminal region is involved in phosphatidylethanolamine-binding and is required for ATG8-PE conjugation.
messages: The flexible region (FR) is required for ATG7-binding.
messages: The handle region (HR) contains the ATG8 interaction motif (AIM) and mediates binding to ATG8. It is crucial for the cytoplasm-to-vacuole targeting pathway (By similarity).

214684:CNM00100
gene id: 214684:CNM00100
uniprot id: Q5K851
names: Similarity
messages: Belongs to the GHMP kinase family. Mevalonate kinase subfamily.

214684:CNJ00980
gene id: 214684:CNJ00980
uniprot id: Q5KAP4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mL54 family.
messages: Mitochondrion

214684:CNG00120
gene id: 214684:CNG00120
uniprot id: Q5KEL2
names: Subcellular Location Annotation
messages: Membrane

214684:CNM02350
gene id: 214684:CNM02350
uniprot id: Q5K7I2
names: Similarity
messages: Belongs to the methyltransferase superfamily. NTM1 family.

214684:CNJ02540
gene id: 214684:CNJ02540
uniprot id: P0CO04
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetylation of histone H3 leads to transcriptional activation. H3K14ac formation by GCN5 is promoted by H3S10ph. H3K14ac can also be formed by ESA1. H3K56ac formation occurs predominantly in newly synthesized H3 molecules during G1, S and G2/M of the cell cycle and may be involved in DNA repair (By similarity).
messages: Belongs to the histone H3 family.
messages: Chromosome
messages: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling (By similarity).
messages: Mono-, di- and trimethylated by the COMPASS complex to form H3K4me1/2/3. H3K4me activates gene expression by regulating transcription elongation and plays a role in telomere length maintenance. H3K4me enrichment correlates with transcription levels, and occurs in a 5' to 3' gradient with H3K4me3 enrichment at the 5'-end of genes, shifting to H3K4me2 and then H3K4me1. Methylated by SET2 to form H3K36me. H3K36me represses gene expression. Methylated by DOT1 to form H3K79me. H3K79me is required for association of SIR proteins with telomeric regions and for telomeric silencing. The COMPASS-mediated formation of H3K4me2/3 and the DOT1-mediated formation of H3K79me require H2BK123ub1 (By similarity).
messages: Nucleus
messages: Phosphorylated to form H3S10ph. H3S10ph promotes subsequent H3K14ac formation and is required for transcriptional activation through TBP recruitment to the promoters (By similarity).
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA (By similarity).
messages: To ensure consistency between histone entries, we follow the 'Brno' nomenclature for histone modifications, with positions referring to those used in the literature for the 'closest' model organism. Due to slight variations in histone sequences between organisms and to the presence of initiator methionine in UniProtKB/Swiss-Prot sequences, the actual positions of modified amino acids in the sequence generally differ. In this entry the following conventions are used: H3K4me1/2/3 = mono-, di- and trimethylated Lys-5; H3K9ac = acetylated Lys-10; H3K9me1 = monomethylated Lys-10; H3S10ph = phosphorylated Ser-11; H3K14ac = acetylated Lys-15; H3K14me2 = dimethylated Lys-15; H3K18ac = acetylated Lys-19; H3K18me1 = monomethylated Lys-19; H3K23ac = acetylated Lys-24; H3K23me1 = monomethylated Lys-24; H3K27ac = acetylated Lys-28; H3K27me1/2/3 = mono-, di- and trimethylated Lys-28; H3K36ac = acetylated Lys-39; H3K36me1/2/3 = mono-, di- and trimethylated Lys-39; H3K56ac = acetylated Lys-59; H3K64ac = acetylated Lys-67; H3K79me1/2/3 = mono-, di- and trimethylated Lys-82.

214684:CNC00950
gene id: 214684:CNC00950
uniprot id: Q5KL30
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat SCAP family.
messages: COPII-coated vesicle membrane
messages: Golgi apparatus membrane

214684:CND01120
gene id: 214684:CND01120
uniprot id: Q5KJ03
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

214684:CNB04050
gene id: 214684:CNB04050
uniprot id: Q5KLU5
names: Function
names: Similarity
messages: Belongs to the GPI family.
messages: In the cytoplasm, catalyzes the conversion of glucose-6-phosphate to fructose-6-phosphate, the second step in glycolysis, and the reverse reaction during gluconeogenesis.

214684:CNA01530
gene id: 214684:CNA01530
uniprot id: Q5KPU2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily.
messages: Catalyzes the reversible phosphorylation of S-methyl-5'-thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates.
messages: Cytoplasm
messages: Homotrimer.
messages: Nucleus

214684:CNB05340
gene id: 214684:CNB05340
uniprot id: Q5KLG7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the snRNP core protein family.
messages: Nucleus
messages: cytosol

214684:CND02780
gene id: 214684:CND02780
uniprot id: Q5KIJ1
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS6 family.

214684:CNH01240
gene id: 214684:CNH01240
uniprot id: Q5KCJ5
names: Similarity
messages: Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.

214684:CNL04810
gene id: 214684:CNL04810
uniprot id: Q5K8R0
names: Subcellular Location Annotation
messages: Membrane

214684:CNG00590
gene id: 214684:CNG00590
uniprot id: Q5KEG6
names: Similarity
names: Subunit
messages: Homodimer.
messages: In the C-terminal section; belongs to the formate--tetrahydrofolate ligase family.
messages: In the N-terminal section; belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.

214684:CNH01320
gene id: 214684:CNH01320
uniprot id: Q5KCK3
names: Similarity
messages: Belongs to the NOC2 family.

214684:CNF03860
gene id: 214684:CNF03860
uniprot id: Q5KEX7
names: Subcellular Location Annotation
messages: Secreted

214684:CNC01870
gene id: 214684:CNC01870
uniprot id: P0CS06
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRM6/GCD10 family.
messages: Heterotetramer; composed of two copies of TRM6 and two copies of TRM61.
messages: Nucleus
messages: Substrate-binding subunit of tRNA (adenine-N(1)-)-methyltransferase, which catalyzes the formation of N(1)-methyladenine at position 58 (m1A58) in initiator methionyl-tRNA.

214684:CNG03730
gene id: 214684:CNG03730
uniprot id: P0CS95
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.

214684:CNC00840
gene id: 214684:CNC00840
uniprot id: Q5KL41
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TIM21 family.
messages: Component of the TIM23 complex.
messages: Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane.
messages: Membrane
messages: Mitochondrion inner membrane

214684:CNH02960
gene id: 214684:CNH02960
uniprot id: Q5KD15
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

214684:CNF03780
gene id: 214684:CNF03780
uniprot id: Q5KEY3
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

214684:CNE02210
gene id: 214684:CNE02210
uniprot id: Q5KGV5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Endomembrane system
messages: Vacuole membrane

214684:CND00610
gene id: 214684:CND00610
uniprot id: Q5KJ55
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NnrE/AIBP family.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Cytoplasm
messages: Mitochondrion

214684:CNF04240
gene id: 214684:CNF04240
uniprot id: Q5KEU2
names: Similarity
messages: Belongs to the OSBP family.

214684:CNH02590
gene id: 214684:CNH02590
uniprot id: Q5KCX9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CLPTM1 family.
messages: Membrane

214684:CNE03800
gene id: 214684:CNE03800
uniprot id: Q5KGF5
names: Function
names: Similarity
messages: Belongs to the CTR86 family.
messages: Essential protein which may be involved in threonine biosynthesis.

214684:CNJ01950
gene id: 214684:CNJ01950
uniprot id: Q5KAE9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ARPC3 family.
messages: Component of the Arp2/3 complex.
messages: Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.
messages: cytoskeleton

214684:CNC01050
gene id: 214684:CNC01050
uniprot id: Q5KL21
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class VI-like SAM-binding methyltransferase superfamily. Isoprenylcysteine carboxyl methyltransferase family.
messages: Endoplasmic reticulum membrane
messages: Membrane

214684:CNK01530
gene id: 214684:CNK01530
uniprot id: Q5K9L8
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.

214684:CNN00650
gene id: 214684:CNN00650
uniprot id: Q5K793
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.
messages: cytoskeleton

214684:CND00350
gene id: 214684:CND00350
uniprot id: Q5KJ78
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZIP transporter (TC 2.A.5) family.
messages: Membrane

214684:CNI03800
gene id: 214684:CNI03800
uniprot id: Q5KB47
names: Similarity
messages: Belongs to the TPX2 family.

214684:CNB01820
gene id: 214684:CNB01820
uniprot id: Q5KMG1
names: Subcellular Location Annotation
messages: Membrane

214684:CNA03460
gene id: 214684:CNA03460
uniprot id: Q5KPB1
names: Similarity
messages: Belongs to the IPP transferase family.

214684:CNF03010
gene id: 214684:CNF03010
uniprot id: Q5KF47
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BMT2 family.
messages: S-adenosyl-L-methionine-dependent methyltransferase that specifically methylates the N(1) position of an adenine present in helix 65 in 25S rRNA.
messages: nucleolus

214684:CND04860
gene id: 214684:CND04860
uniprot id: Q5KHY6
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.

214684:CNF04150
gene id: 214684:CNF04150
uniprot id: Q5KEV1
names: Similarity
messages: Belongs to the universal ribosomal protein uS5 family.

214684:CNL05070
gene id: 214684:CNL05070
uniprot id: Q5K8N2
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

214684:CNE03790
gene id: 214684:CNE03790
uniprot id: Q5KGF6
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chloride channel (TC 2.A.49) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

214684:CNC01970
gene id: 214684:CNC01970
uniprot id: Q5KKS9
names: Similarity
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the N-terminal section; belongs to the AAA ATPase family.

214684:CNA06920
gene id: 214684:CNA06920
uniprot id: Q5KND0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the V-ATPase H subunit family.
messages: Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments.
messages: V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex.

214684:CND06100
gene id: 214684:CND06100
uniprot id: Q5KHL0
names: Similarity
messages: Belongs to the amino acid/polyamine transporter 2 family.

214684:CNA02480
gene id: 214684:CNA02480
uniprot id: Q5KPK4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. BUD23/WBSCR22 family.
messages: Cytoplasm
messages: Nucleus

214684:CNA02830
gene id: 214684:CNA02830
uniprot id: Q5KPH0
names: Similarity
messages: Belongs to the ClpA/ClpB family.

214684:CNE03090
gene id: 214684:CNE03090
uniprot id: P0CO88
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family. NUBP1/NBP35 subfamily.
messages: Binds 4 [4Fe-4S] clusters per heterotetramer. Contains two stable clusters in the N-termini of NBP35 and two labile, bridging clusters between subunits of the NBP35-CFD1 heterotetramer.
messages: Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery. Required for maturation of extramitochondrial Fe-S proteins. The NBP35-CFD1 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins.
messages: Cytoplasm
messages: Heterotetramer of 2 NBP35 and 2 CFD1 chains.

214684:CNE02020
gene id: 214684:CNE02020
uniprot id: Q5KGX3
names: Function
names: Subcellular Location Annotation
messages: Essential factor for the assembly of mitochondrial NADH:ubiquinone oxidoreductase complex (complex I).
messages: Membrane
messages: Mitochondrion inner membrane
messages: Nucleus

214684:CNF03360
gene id: 214684:CNF03360
uniprot id: Q5KF23
names: Similarity
messages: Belongs to the complex I 30 kDa subunit family.

214684:CNH02760
gene id: 214684:CNH02760
uniprot id: Q5KCZ5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.

214684:CNF02230
gene id: 214684:CNF02230
uniprot id: Q5KFC5
names: Similarity
messages: Belongs to the MAK16 family.

214684:CND05340
gene id: 214684:CND05340
uniprot id: Q5KHT5
names: Subcellular Location Annotation
messages: Membrane

214684:CNH00330
gene id: 214684:CNH00330
uniprot id: Q5KCA3
names: Similarity
messages: Belongs to the ribose-phosphate pyrophosphokinase family.

214684:CNB04360
gene id: 214684:CNB04360
uniprot id: Q5KLR2
names: Cofactor
messages: Divalent metal ions. Mg(2+) is the most effective.

214684:CNI01480
gene id: 214684:CNI01480
uniprot id: P0CQ54
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in mitochondrial genome encoded proteins translation. Involved in the binding of tRNA to the ribosomes (By similarity).
messages: Mitochondrion
messages: Part of the mitochondrial small ribosomal subunit.

214684:CNC06970
gene id: 214684:CNC06970
uniprot id: Q5KJD1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane
messages: Mitochondrion inner membrane

214684:CNK00270
gene id: 214684:CNK00270
uniprot id: Q5K9Y4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

214684:CNB05510
gene id: 214684:CNB05510
uniprot id: Q5KLF0
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL28 family.

214684:CNG02500
gene id: 214684:CNG02500
uniprot id: Q5KDX1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ING family.
messages: Component of an histone acetyltransferase complex.
messages: Component of an histone acetyltransferase complex. Interacts with H3K4me3 and to a lesser extent with H3K4me2.
messages: Nucleus
messages: The PHD-type zinc finger mediates the binding to H3K4me3.

214684:CNJ02740
gene id: 214684:CNJ02740
uniprot id: Q5KA72
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

214684:CNM02320
gene id: 214684:CNM02320
uniprot id: Q5K7I5
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules. The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain. The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel.

214684:CNE03970
gene id: 214684:CNE03970
uniprot id: Q5KGD8
names: Similarity
messages: Belongs to the OSBP family.

214684:CNE02370
gene id: 214684:CNE02370
uniprot id: P0CP96
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. FKBP2 subfamily.
messages: Endoplasmic reticulum
messages: Inhibited by both FK506 and rapamycin.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides (By similarity).

214684:CNN00090
gene id: 214684:CNN00090
uniprot id: Q5K7E8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRS1 family.
messages: Involved in ribosomal large subunit assembly.
messages: Nucleus

214684:CNL04840
gene id: 214684:CNL04840
uniprot id: Q5K8Q6
uniprot id: Q5K8Q7
names: Similarity
messages: Belongs to the glycosyl hydrolase 5 (cellulase A) family.

214684:CNB00590
gene id: 214684:CNB00590
uniprot id: Q5KMT1
names: Similarity
messages: Belongs to the RutC family.

214684:CNF00400
gene id: 214684:CNF00400
uniprot id: Q5KFV8
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family. UMP-CMP kinase subfamily.
messages: Binds 1 Mg(2+) ion per monomer.
messages: Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and dUMP as phosphate acceptors, but can also use CMP, dCMP and AMP.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Monomer.
messages: Nucleus

214684:CNE05250
gene id: 214684:CNE05250
uniprot id: Q5KG11
names: Similarity
messages: Belongs to the enolase family.

214684:CNB03030
gene id: 214684:CNB03030
uniprot id: Q5KM46
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.

214684:CNJ00280
gene id: 214684:CNJ00280
uniprot id: Q5KAW0
names: Subcellular Location Annotation
messages: Nucleus

214684:CNA01470
gene id: 214684:CNA01470
uniprot id: Q5KPU8
names: Similarity
messages: Belongs to the glycosyltransferase 32 family.

214684:CNK03420
gene id: 214684:CNK03420
uniprot id: P0CO42
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family. AK2 subfamily.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism. Adenylate kinase activity is critical for regulation of the phosphate utilization and the AMP de novo biosynthesis pathways.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Mitochondrion intermembrane space
messages: Monomer.
messages: cytosol

214684:CNF03960
gene id: 214684:CNF03960
uniprot id: Q5KEW7
names: Similarity
messages: Belongs to the yippee family.

214684:CND00390
gene id: 214684:CND00390
uniprot id: Q5KJ74
names: Subcellular Location Annotation
messages: Membrane

214684:CNB05570
gene id: 214684:CNB05570
uniprot id: Q5KLE4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the WD repeat COPB2 family.
messages: COPI-coated vesicle membrane
messages: Golgi apparatus membrane
messages: Membrane
messages: Oligomeric complex that consists of at least the alpha, beta, beta', gamma, delta, epsilon and zeta subunits.
messages: The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.

214684:CND00800
gene id: 214684:CND00800
uniprot id: Q5KJ33
names: Similarity
messages: Belongs to the RNR ribonuclease family.

214684:CNE01140
gene id: 214684:CNE01140
uniprot id: Q5KH61
names: Similarity
messages: Belongs to the MEMO1 family.

214684:CNL05870
gene id: 214684:CNL05870
uniprot id: Q5K8F6
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

214684:CNL05030
gene id: 214684:CNL05030
uniprot id: Q5K8N7
names: Similarity
messages: Belongs to the OSBP family.

214684:CNB01810
gene id: 214684:CNB01810
uniprot id: Q5KMG2
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

214684:CNB03110
gene id: 214684:CNB03110
uniprot id: Q5KM38
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NOP14 family.
messages: Involved in nucleolar processing of pre-18S ribosomal RNA. Has a role in the nuclear export of 40S pre-ribosomal subunit to the cytoplasm.
messages: nucleolus

214684:CNJ00690
gene id: 214684:CNJ00690
uniprot id: Q5KAS3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine-cytosine permease (2.A.39) family.
messages: Membrane

214684:CNE03420
gene id: 214684:CNE03420
uniprot id: Q5KGJ2
names: Similarity
messages: Belongs to the pinin family.

214684:CNA05840
gene id: 214684:CNA05840
uniprot id: F5HH24
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 61 family.
messages: Has a modular structure: an endo-beta-1,4-glucanase catalytic module at the N-terminus, a linker rich in serines and threonines, and a C-terminal carbohydrate-binding module (CBM). The genes for catalytic modules and CBMs seem to have evolved separately and have been linked by gene fusion.
messages: Has endoglucanase activity on substrates containing beta-1,4 glycosidic bonds. Involved in the degradation of complex natural cellulosic substrates.
messages: Secreted

214684:CNE03060
gene id: 214684:CNE03060
uniprot id: Q5KGM8
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL6 family.

214684:CNJ02530
gene id: 214684:CNJ02530
uniprot id: Q5KA92
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 11 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex.
messages: Nucleus

214684:CNC00110
gene id: 214684:CNC00110
uniprot id: Q5KLB1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELO family.
messages: Membrane

214684:CNC02150
gene id: 214684:CNC02150
uniprot id: Q5KKR0
names: Similarity
messages: Belongs to the eIF-2-beta/eIF-5 family.

214684:CNE01950
gene id: 214684:CNE01950
uniprot id: Q5KGY1
names: Subcellular Location Annotation
messages: Membrane

214684:CNC04600
gene id: 214684:CNC04600
uniprot id: Q5KK16
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-II family.
messages: Functions in the biosynthesis of the anionic phospholipids phosphatidylglycerol and cardiolipin.
messages: Mitochondrion

214684:CNI01520
gene id: 214684:CNI01520
uniprot id: Q5KBT0
names: Similarity
messages: Belongs to the UPF0357 family.

214684:CNL05710
gene id: 214684:CNL05710
uniprot id: Q5K8H1
names: Similarity
messages: Belongs to the peptidase M16 family.

214684:CNC03390
gene id: 214684:CNC03390
uniprot id: Q5KKD4
names: Subcellular Location Annotation
messages: Membrane

214684:CNI02920
gene id: 214684:CNI02920
uniprot id: Q5KBD5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the snRNP Sm proteins family.
messages: Involved in pre-mRNA splicing. Binds and is required for the stability of snRNA U1, U2, U4 and U5 which contain a highly conserved structural motif called the Sm binding site. Involved in cap modification.
messages: Nucleus

214684:CNA07770
gene id: 214684:CNA07770
uniprot id: Q5KN45
names: Similarity
messages: Belongs to the glycosyl hydrolase 5 (cellulase A) family.

214684:CNC03760
gene id: 214684:CNC03760
uniprot id: Q5KK99
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS12 family.

214684:CNF01240
gene id: 214684:CNF01240
uniprot id: P0CQ76
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent RNA helicase involved nonsense-mediated mRNA decay and ribosome biogenesis through rRNA processing.
messages: Associates with polysomes.
messages: Belongs to the DEAD box helicase family. DDX5/DBP2 subfamily.
messages: Cytoplasm
messages: Nucleus
messages: The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.

214684:CNG01860
gene id: 214684:CNG01860
uniprot id: Q5KE37
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZIP transporter (TC 2.A.5) family.
messages: Membrane

214684:CNL04250
gene id: 214684:CNL04250
uniprot id: Q5K8W6
names: Similarity
messages: Belongs to the pyridoxine kinase family.

214684:CNK02230
gene id: 214684:CNK02230
uniprot id: P0CN14
names: Activity Regulation
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. DOT1 family.
messages: Histone methyltransferase that specifically trimethylates histone H3 to form H3K79me3. This methylation is required for telomere silencing and for the pachytene checkpoint during the meiotic cell cycle by allowing the recruitment of RAD9 to double strand breaks. Nucleosomes are preferred as substrate compared to free histone.
messages: In contrast to other lysine histone methyltransferases, it does not contain a SET domain, suggesting the existence of another mechanism for methylation of lysine residues of histones.
messages: Nucleus
messages: Ubiquitination of histone H2B to form H2BK123ub1 is required for efficient DOT1 methyltransferase activity on histone H3.

214684:CNG01350
gene id: 214684:CNG01350
uniprot id: Q5KE88
names: Similarity
messages: Belongs to the AFG1 ATPase family.

214684:CNH00690
gene id: 214684:CNH00690
uniprot id: Q5KCE0
names: Similarity
messages: Belongs to the peptidase A22B family.

214684:CNF02400
gene id: 214684:CNF02400
uniprot id: Q5KFA7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLA1 family.
messages: Cell membrane
messages: Endosome membrane
messages: Membrane

214684:CNA01160
gene id: 214684:CNA01160
uniprot id: Q5KPY2
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

214684:CNA02290
gene id: 214684:CNA02290
uniprot id: Q5KPM2
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

214684:CNA06760
gene id: 214684:CNA06760
uniprot id: Q5KNE6
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

214684:CNA04650
gene id: 214684:CNA04650
uniprot id: Q5KP06
names: Function
names: Similarity
messages: Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells.
messages: Belongs to the actin family.

214684:CNC02680
gene id: 214684:CNC02680
uniprot id: Q5KKK7
names: Subcellular Location Annotation
messages: Membrane

214684:CNK00330
gene id: 214684:CNK00330
uniprot id: Q5K9X9
names: Subcellular Location Annotation
messages: Cytoplasm

214684:CNB00610
gene id: 214684:CNB00610
uniprot id: P0CR06
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: ATP-binding RNA helicase involved in the biogenesis of 60S ribosomal subunits and is required for the normal formation of 25S and 5.8S rRNAs.
messages: Belongs to the DEAD box helicase family. DDX54/DBP10 subfamily.
messages: The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.
messages: nucleolus

214684:CNK02480
gene id: 214684:CNK02480
uniprot id: P0CO68
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MDM12 family.
messages: Component of the ER-mitochondria encounter structure (ERMES) or MDM complex, composed of MMM1, MDM10, MDM12 and MDM34. A MMM1 homodimer associates with one molecule of MDM12 on each side in a pairwise head-to-tail manner, and the SMP-LTD domains of MMM1 and MDM12 generate a continuous hydrophobic tunnel for phospholipid trafficking.
messages: Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria. MDM12 is required for the interaction of the ER-resident membrane protein MMM1 and the outer mitochondrial membrane-resident beta-barrel protein MDM10. The MDM12-MMM1 subcomplex functions in the major beta-barrel assembly pathway that is responsible for biogenesis of all mitochondrial outer membrane beta-barrel proteins, and acts in a late step after the SAM complex. The MDM10-MDM12-MMM1 subcomplex further acts in the TOM40-specific pathway after the action of the MDM12-MMM1 complex. Essential for establishing and maintaining the structure of mitochondria and maintenance of mtDNA nucleoids.
messages: Endoplasmic reticulum membrane
messages: Mitochondrion outer membrane
messages: The SMP-LTD domain is a barrel-like domain that can bind various types of glycerophospholipids in its interior and mediate their transfer between two adjacent bilayers.

214684:CNI00310
gene id: 214684:CNI00310
uniprot id: Q5KC43
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

214684:CNI01090
gene id: 214684:CNI01090
uniprot id: Q5KBW9
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL19 family.

214684:CNJ01180
gene id: 214684:CNJ01180
uniprot id: Q5KAM4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fatty acid desaturase type 1 family.
messages: Membrane

214684:CND02110
gene id: 214684:CND02110
uniprot id: Q5KIQ7
names: Similarity
messages: Belongs to the proteasome subunit p55 family.

214684:CND04990
gene id: 214684:CND04990
uniprot id: Q5KHX3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0014 family.
messages: Membrane

214684:CND01530
gene id: 214684:CND01530
uniprot id: Q5KIW3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the rad21 family.
messages: Nucleus

214684:CNA07450
gene id: 214684:CNA07450
uniprot id: Q5KN77
names: Subcellular Location Annotation
messages: Membrane

214684:CNN00030
gene id: 214684:CNN00030
uniprot id: Q5K7F5
names: Subcellular Location Annotation
messages: Membrane

214684:CNH01430
gene id: 214684:CNH01430
uniprot id: P0CS08
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TRM61 family.
messages: Catalytic subunit of tRNA (adenine-N(1)-)-methyltransferase, which catalyzes the formation of N(1)-methyladenine at position 58 (m1A58) in initiator methionyl-tRNA.
messages: Heterotetramer; composed of two copies of TRM6 and two copies of TRM61.
messages: Nucleus

214684:CNA00430
gene id: 214684:CNA00430
uniprot id: Q5KQ51
names: Similarity
messages: Belongs to the OBAP family.

214684:CNC03000
gene id: 214684:CNC03000
uniprot id: Q5KKH4
names: Similarity
messages: Belongs to the CCDC124 family.

214684:CNC01410
gene id: 214684:CNC01410
uniprot id: Q5KKY5
names: Similarity
messages: Belongs to the universal ribosomal protein uS10 family.

214684:CNJ02640
gene id: 214684:CNJ02640
uniprot id: Q5KA82
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase PH family.
messages: nucleolus

214684:CNI00070
gene id: 214684:CNI00070
uniprot id: Q5KC66
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metaxin family.
messages: Membrane
messages: Mitochondrion outer membrane

214684:CNH01540
gene id: 214684:CNH01540
uniprot id: Q5KCL9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COG8 family.
messages: Membrane

214684:CNC00410
gene id: 214684:CNC00410
uniprot id: Q5KL83
names: Subcellular Location Annotation
messages: Membrane

214684:CNF00730
gene id: 214684:CNF00730
uniprot id: Q5KFS5
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.

214684:CND04790
gene id: 214684:CND04790
uniprot id: Q5KHZ2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GPN-loop GTPase family.
messages: Binds to RNA polymerase II.
messages: Cytoplasm
messages: Nucleus
messages: Small GTPase required for proper nuclear import of RNA polymerase II (RNAPII). May act at an RNAP assembly step prior to nuclear import.

214684:CNL04260
gene id: 214684:CNL04260
uniprot id: Q5K8W5
names: Similarity
messages: Belongs to the heat shock protein 70 family.

214684:CNC04470
gene id: 214684:CNC04470
uniprot id: Q5KK28
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ERG4/ERG24 family.
messages: Membrane

214684:CNF04060
gene id: 214684:CNF04060
uniprot id: Q5KEW0
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

214684:CNF01290
gene id: 214684:CNF01290
uniprot id: P0CR94
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the small Tim family.
messages: Heterohexamer; composed of 3 copies of TIM8 and 3 copies of TIM13, named soluble 70 kDa complex. Associates with the TIM22 complex, whose core is composed of TIM22 and TIM54. Interacts with the transmembrane regions of multi-pass transmembrane proteins in transit (By similarity).
messages: Mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space. The TIM8-TIM13 complex is non essential and only mediates the import of few proteins, while the predominant TIM9-TIM10 70 kDa complex is crucial and mediates the import of much more proteins (By similarity).
messages: Mitochondrion inner membrane
messages: The twin CX3C motif contains 4 conserved Cys residues that form 2 disulfide bonds in the mitochondrial intermembrane space. However, during the transit of TIM8 from cytoplasm into mitochondrion, the Cys residues probably coordinate zinc, thereby preventing folding and allowing its transfer across mitochondrial outer membrane (By similarity).

214684:CNI01740
gene id: 214684:CNI01740
uniprot id: Q5KBQ7
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

214684:CNH03700
gene id: 214684:CNH03700
uniprot id: Q5K920
names: Similarity
messages: Belongs to the group II decarboxylase family.

214684:CNH00970
gene id: 214684:CNH00970
uniprot id: P0CS62
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activated by C-terminal proteolytic cleavage by signaling protease (probably palB/RIM13) at neutral to alkaline ambient pH.
messages: Belongs to the pacC/RIM101 family.
messages: Binds to DNA. Interacts with RIM20, which binds to the YPX[LI] motifs and is required for proteolytic processing (By similarity).
messages: Cytoplasm
messages: Nucleus
messages: Transcription factor that mediates regulation of both acid- and alkaline-expressed genes in response to ambient pH. At alkaline ambient pH, activates transcription of alkaline-expressed genes (including RIM101 itself) and represses transcription of acid-expressed genes (By similarity).

214684:CND01400
gene id: 214684:CND01400
uniprot id: Q5KIX6
names: Similarity
messages: Belongs to the MTFP1 family.

214684:CNA01100
gene id: 214684:CNA01100
uniprot id: Q5KPY7
names: Similarity
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.

214684:CNF01070
gene id: 214684:CNF01070
uniprot id: A0A0S2M5S6
uniprot id: P0CQ04
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRM1 family.
messages: Cell membrane
messages: Involved in cell fusion during mating by stabilizing the plasma membrane fusion event.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

214684:CNE04030
gene id: 214684:CNE04030
uniprot id: Q5KGD2
names: Function
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.
messages: Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.

214684:CNA05650
gene id: 214684:CNA05650
uniprot id: Q5KNQ9
names: Similarity
messages: Belongs to the peptidase A1 family.

214684:CNK00880
gene id: 214684:CNK00880
uniprot id: Q5K9T0
names: Similarity
messages: Belongs to the iron/ascorbate-dependent oxidoreductase family.

214684:CNA06560
gene id: 214684:CNA06560
uniprot id: Q5KNG6
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. UreG subfamily.

214684:CNB05150
gene id: 214684:CNB05150
uniprot id: Q5KLI3
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.

214684:CND01080
gene id: 214684:CND01080
uniprot id: Q5KJ07
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the copper transporter (Ctr) (TC 1.A.56) family. SLC31A subfamily.
messages: Membrane

214684:CNE00520
gene id: 214684:CNE00520
uniprot id: P0CP66
names: Activity Regulation
names: Domain
names: Function
names: PTM
names: Similarity
messages: Activated by tyrosine and threonine phosphorylation.
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MAP kinase subfamily.
messages: Dually phosphorylated on Thr-181 and Tyr-183, which activates the enzyme.
messages: Responds to activation by environmental stress by phosphorylating downstream targets.
messages: The TXY motif contains the threonine and tyrosine residues whose phosphorylation activates the MAP kinases.

214684:CND03340
gene id: 214684:CND03340
uniprot id: Q5KID6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COPE family.
messages: Cytoplasm
messages: Membrane
messages: The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. The coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.

214684:CNN01530
gene id: 214684:CNN01530
uniprot id: P0CM56
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PC-esterase family. CASD1 subfamily.
messages: Membrane
messages: Probable O-acetyltransferase required for the O-acetylation of the capsular glucoronoxylmannans (GXM) involved in virulence.

214684:CNF00420
gene id: 214684:CNF00420
uniprot id: Q5KFV6
names: Similarity
messages: Belongs to the STXBP/unc-18/SEC1 family.

214684:CNL04080
gene id: 214684:CNL04080
uniprot id: P0CO00
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetylated once deposited into chromatin.
messages: Belongs to the histone H2A family.
messages: Chromosome
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA. H2A or its variant H2A.Z forms a heterodimer with H2B. H2A.Z associates with the VPS72/SWC2 subunit of the SWR1 chromatin remodeling complex. Interacts also with RBP1/DNA-directed RNA polymerase II largest subunit (By similarity).
messages: Variant histone H2A which can replace H2A in some nucleosomes. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. This variant is enriched at promoters, it may keep them in a repressed state until the appropriate activation signal is received. Near telomeres, it may counteract gene silencing caused by the spread of heterochromatin proteins. Required for the RNA polymerase II and SPT15/TBP recruitment to the target genes. Involved in chromosome stability (By similarity).

214684:CNF00120
gene id: 214684:CNF00120
uniprot id: Q5KFY9
names: Similarity
messages: Belongs to the peptidase S28 family.

214684:CNB04170
gene id: 214684:CNB04170
uniprot id: Q5KLT1
names: Function
names: Similarity
messages: Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration.
messages: Belongs to the adaptor complexes large subunit family.

214684:CNL06630
gene id: 214684:CNL06630
uniprot id: Q5K880
names: Similarity
messages: Belongs to the small GTPase superfamily. Arf family.

214684:CNA06880
gene id: 214684:CNA06880
uniprot id: Q5KND4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
messages: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.
messages: Mitochondrion
messages: Nucleus

214684:CNC00290
gene id: 214684:CNC00290
uniprot id: Q5KL95
names: Subcellular Location Annotation
messages: Membrane

214684:CNM00470
gene id: 214684:CNM00470
uniprot id: Q5K815
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

214684:CNI00690
gene id: 214684:CNI00690
uniprot id: P0CR34
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Component of the microsomal membrane bound fatty acid elongation system, which produces the 26-carbon very long-chain fatty acids (VLCFA) from palmitate. Catalyzes the reduction of the 3-ketoacyl-CoA intermediate that is formed in each cycle of fatty acid elongation. VLCFAs serve as precursors for ceramide and sphingolipids.
messages: Endoplasmic reticulum membrane

214684:CNN01340
gene id: 214684:CNN01340
uniprot id: Q5K727
names: Similarity
messages: Belongs to the DCC1 family.

214684:CND03550
gene id: 214684:CND03550
uniprot id: Q5KIB6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EBP2 family.
messages: nucleolus

214684:CNK01390
gene id: 214684:CNK01390
uniprot id: Q5K9N1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ING family.
messages: Component of an histone acetyltransferase complex.
messages: Component of an histone acetyltransferase complex. Interacts with H3K4me3 and to a lesser extent with H3K4me2.
messages: Nucleus
messages: The PHD-type zinc finger mediates the binding to H3K4me3.

214684:CNC01540
gene id: 214684:CNC01540
uniprot id: Q5KKX2
names: Similarity
messages: Belongs to the MYBBP1A family.

214684:CNA04430
gene id: 214684:CNA04430
uniprot id: P0CR22
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associated with the spliceosome.
messages: Belongs to the RSE1 family.
messages: Involved in pre-mRNA splicing and cell cycle control.
messages: Nucleus

214684:CNK01940
gene id: 214684:CNK01940
uniprot id: Q5K9H3
names: Similarity
messages: Belongs to the prenylcysteine oxidase family.

214684:CNA04190
gene id: 214684:CNA04190
uniprot id: P0CS66
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family. AKR/ZDHHC17 subfamily.
messages: Early endosome membrane
messages: Golgi apparatus membrane
messages: It is uncertain whether Met-1 or Met-5 is the initiator.
messages: Palmitoyltransferase specific for casein kinase 1.
messages: The DHHC domain is required for palmitoyltransferase activity.

214684:CNK01760
gene id: 214684:CNK01760
uniprot id: Q5K9J1
names: Similarity
messages: Belongs to the opioid growth factor receptor family.

214684:CNN02410
gene id: 214684:CNN02410
uniprot id: P0CM36
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATG5 family.
messages: Conjugated to ATG12; which is essential for autophagy.
messages: Conjugated with ATG12.
messages: Involved in cytoplasm to vacuole transport (Cvt) and autophagic vesicle formation. Autophagy is essential for maintenance of amino acid levels and protein synthesis under nitrogen starvation. Required for selective autophagic degradation of the nucleus (nucleophagy). Also required for mitophagy, which eliminates defective or superfluous mitochondria in order to fulfill cellular energy requirements and prevent excess ROS production. Conjugation with ATG12, through a ubiquitin-like conjugating system involving ATG7 as an E1-like activating enzyme and ATG10 as an E2-like conjugating enzyme, is essential for its function. The ATG12-ATG5 conjugate acts as an E3-like enzyme which is required for lipidation of ATG8 and ATG8 association to the vesicle membranes (By similarity).
messages: Preautophagosomal structure membrane

214684:CNB05360
gene id: 214684:CNB05360
uniprot id: Q5KLG5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as component of the MCM2-7 complex (MCM complex) which is the replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity.
messages: Belongs to the MCM family.
messages: Component of the MCM2-7 complex.
messages: Nucleus

214684:CNG00570
gene id: 214684:CNG00570
uniprot id: Q5KEG8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in the mitochondria. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Mitochondrion
messages: Subunit of the heterotrimeric GatCAB amidotransferase (AdT) complex, composed of A, B and C subunits.

214684:CNJ02350
gene id: 214684:CNJ02350
uniprot id: P0CQ24
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase M67A family. CSN5 subfamily.
messages: Catalytic Component of the COP9 signalosome (CSN) complex that acts as an regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunit of SCF-type E3 ubiquitin-protein ligase complexes.
messages: Component of the COP9 signalosome (CSN) complex.
messages: Cytoplasm
messages: Nucleus
messages: The JAMM motif is essential for the protease activity of the CSN complex resulting in deneddylation of cullins. It constitutes the catalytic center of the complex (By similarity).

214684:CNF01730
gene id: 214684:CNF01730
uniprot id: P0CO72
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 4 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).
messages: Component of the Mediator complex.
messages: Nucleus

214684:CND00200
gene id: 214684:CND00200
uniprot id: Q5KJ90
names: Subcellular Location Annotation
messages: Nucleus

214684:CND03865
gene id: 214684:CND03865
uniprot id: A0A0S2LII6
uniprot id: P0CQ16
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of misfolded, unassembled or oxidatively damaged polypeptides as well as certain short-lived regulatory proteins in the mitochondrial matrix. May also have a chaperone function in the assembly of inner membrane protein complexes. Participates in the regulation of mitochondrial gene expression and in the maintenance of the integrity of the mitochondrial genome. Binds to mitochondrial DNA in a site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: Homohexamer or homoheptamer. Organized in a ring with a central cavity.
messages: Mitochondrion matrix

214684:CND01140
gene id: 214684:CND01140
uniprot id: Q5KJ01
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: In the N-terminal section; belongs to the HesA/MoeB/ThiF family. UBA4 subfamily.

214684:CNI03610
gene id: 214684:CNI03610
uniprot id: Q5KB67
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the glyoxalase I family.
messages: Binds 1 zinc ion per subunit. In the homodimer, two zinc ions are bound between subunits.
messages: Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione.

214684:CNC03060
gene id: 214684:CNC03060
uniprot id: Q5KKG8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP12 family.
messages: Mitochondrion

214684:CNC04320
gene id: 214684:CNC04320
uniprot id: Q5KK43
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.

214684:CNH01690
gene id: 214684:CNH01690
uniprot id: Q5KCN5
names: Subcellular Location Annotation
messages: Membrane

214684:CNK01740
gene id: 214684:CNK01740
uniprot id: Q5K9J3
names: Similarity
messages: Belongs to the GHMP kinase family. Mevalonate kinase subfamily.

214684:CNG03870
gene id: 214684:CNG03870
uniprot id: Q5KDI4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SNUT3 family.
messages: May play a role in mRNA splicing.
messages: Nucleus
messages: Part of a tri-snRNP complex.

214684:CNL03960
gene id: 214684:CNL03960
uniprot id: Q5K8Z3
names: Similarity
messages: Belongs to the universal ribosomal protein uL2 family.

214684:CNF04290
gene id: 214684:CNF04290
uniprot id: Q5KET8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MCM10 family.
messages: Nucleus

214684:CNK02100
gene id: 214684:CNK02100
uniprot id: Q5K9F7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ETF beta-subunit/FixA family.
messages: Binds 1 AMP per subunit.
messages: Binds 1 FAD per dimer.
messages: Heterodimer of an alpha and a beta subunit.
messages: Mitochondrion matrix
messages: The electron transfer flavoprotein serves as a specific electron acceptor for several dehydrogenases, including five acyl-CoA dehydrogenases, glutaryl-CoA and sarcosine dehydrogenase. It transfers the electrons to the main mitochondrial respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase).

214684:CNA04290
gene id: 214684:CNA04290
uniprot id: Q5KP39
names: Function
names: Similarity
names: Subunit
messages: Belongs to the V-ATPase V0D/AC39 subunit family.
messages: Subunit of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments. This subunit is a non-integral membrane component of the membrane pore domain and is required for proper assembly of the V0 sector. Might be involved in the regulated assembly of V1 subunits onto the membrane sector or alternatively may prevent the passage of protons through V0 pores.
messages: V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex.

214684:CNH03260
gene id: 214684:CNH03260
uniprot id: Q5KD46
names: Subcellular Location Annotation
messages: Nucleus

214684:CNG04000
gene id: 214684:CNG04000
uniprot id: Q5KDH2
names: Similarity
messages: Belongs to the protein kinase superfamily.

214684:CNM00850
gene id: 214684:CNM00850
uniprot id: Q5K7Y5
names: Similarity
messages: Belongs to the HGH1 family.

214684:CNL04960
gene id: 214684:CNL04960
uniprot id: P0CQ46
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. GB1/RHD3 GTPase family. RHD3 subfamily.
messages: Cooperates with the reticulon proteins and tubule-shaping DP1 family proteins to generate and maintain the structure of the tubular endoplasmic reticulum network. Has GTPase activity, which is required for its function in ER organization.
messages: Endoplasmic reticulum membrane

214684:CNI01490
gene id: 214684:CNI01490
uniprot id: Q5KBT3
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which may be involved in intracellular homeostatic regulation of pyridoxal 5'-phosphate (PLP), the active form of vitamin B6.

214684:CND02960
gene id: 214684:CND02960
uniprot id: Q5KIH4
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS17 family.

214684:CNE00920
gene id: 214684:CNE00920
uniprot id: Q5KH84
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MET18/MMS19 family.
messages: Key component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into apoproteins specifically involved in DNA metabolism and genomic integrity. In the CIA complex, MMS19 acts as an adapter between early-acting CIA components and a subset of cellular target iron-sulfur proteins.
messages: Nucleus

214684:CND00150
gene id: 214684:CND00150
uniprot id: Q5KJ95
names: Subcellular Location Annotation
messages: Membrane

214684:CNE02640
gene id: 214684:CNE02640
uniprot id: Q5KGR3
names: Similarity
messages: Belongs to the peptidase M14 family.

214684:CNG04360
gene id: 214684:CNG04360
uniprot id: Q5KDD6
names: Similarity
messages: Belongs to the universal ribosomal protein uS12 family.

214684:CNB01190
gene id: 214684:CNB01190
uniprot id: P0CP18
names: Developmental Stage
names: Disruption Phenotype
names: Function
messages: Expressed abundantly under sexual development conditions.
messages: Expression is not seen in haploid cells where both copies of the gene are deleted and there is no discernible phenotype with respect to haplotype growth in strains with complete deletions. However, there is a complete absence of sexual development and strains fail to form dikaryotic filaments/spores. Where only a single copy is present in a wild-type and mutant mating pair sexual development is indistinguishable from a wild-type mating pair. Expression is up-regulated during sexual development.
messages: Required for developmental progression after cells of opposite mating types fuse with one another, essential for processes common to both dikaryotic filament formation and monokaryotic fruiting. A direct target for transcription factors Sxi1-alpha and Sxi2-a.

214684:CNA01640
gene id: 214684:CNA01640
uniprot id: Q5KPT1
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M20A family.
messages: Binds 2 manganese ions per subunit.

214684:CNC03280
gene id: 214684:CNC03280
uniprot id: P0CN38
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Mitochondrion

214684:CNG03640
gene id: 214684:CNG03640
uniprot id: Q5KDK4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Nth/MutY family.
messages: Bifunctional DNA N-glycosylase with associated apurinic/apyrimidinic (AP) lyase function that catalyzes the first step in base excision repair (BER), the primary repair pathway for the repair of oxidative DNA damage. The DNA N-glycosylase activity releases the damaged DNA base from DNA by cleaving the N-glycosidic bond, leaving an AP site. The AP lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination. Primarily recognizes and repairs oxidative base damage of pyrimidines.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mitochondrion
messages: Nucleus

214684:CNE02750
gene id: 214684:CNE02750
uniprot id: P0CS28
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the WD repeat PROPPIN family.
messages: Component of the PI(3,5)P2 regulatory complex.
messages: Endosome membrane
messages: Preautophagosomal structure membrane
messages: The L/FRRG motif is essential for the cytoplasm to vacuole transport (Cvt) pathway, for the recruitment of ATG8 and ATG16 to the PAS in nutrient-rich medium, and for its recruitment to and dissociation from the PAS under starvation conditions.
messages: The N-terminus might form a beta-propeller domain involved in specific binding to phosphatidylinositol 3,5-bisphosphate (PIP2), leading to the association of the protein to the membrane.
messages: The PI(3,5)P2 regulatory complex regulates both the synthesis and turnover of phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2). Necessary for proper vacuole morphology. Plays an important role in osmotically-induced vacuole fragmentation. Required for cytoplasm to vacuole transport (Cvt) vesicle formation, pexophagy and starvation-induced autophagy. Involved in correct ATG9 trafficking to the pre-autophagosomal structure. Might also be involved in premeiotic DNA replication (By similarity).
messages: Vacuole membrane

214684:CNC04040
gene id: 214684:CNC04040
uniprot id: Q5KK71
names: Function
names: Similarity
messages: Catalyzes three sequential steps of tetrahydrofolate biosynthesis.
messages: In the C-terminal section; belongs to the DHPS family.
messages: In the N-terminal section; belongs to the DHNA family.
messages: In the central section; belongs to the HPPK family.

214684:CNB02140
gene id: 214684:CNB02140
uniprot id: P0CQ20
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.
messages: Cleaves proteins, imported into the mitochondrion, to their mature size. While most mitochondrial precursor proteins are processed to the mature form in one step by mitochondrial processing peptidase (MPP), the sequential cleavage by MIP of an octapeptide after initial processing by MPP is a required step for a subgroup of nuclear-encoded precursor proteins destined for the matrix or the inner membrane (By similarity).
messages: Mitochondrion matrix

214684:CNB01880
gene id: 214684:CNB01880
uniprot id: Q5KMF6
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

214684:CNA05990
gene id: 214684:CNA05990
uniprot id: Q5KNM3
names: Similarity
messages: Belongs to the TBCC family.

214684:CNC05360
gene id: 214684:CNC05360
uniprot id: Q5KJU2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Cytoplasm

214684:CNN02270
gene id: 214684:CNN02270
uniprot id: Q5K6U2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

214684:CNA05460
gene id: 214684:CNA05460
uniprot id: Q5KNS6
names: Subcellular Location Annotation
messages: Nucleus

214684:CNG00560
gene id: 214684:CNG00560
uniprot id: Q5KEG9
names: Similarity
messages: Belongs to the PP2C family.

214684:CNJ01930
gene id: 214684:CNJ01930
uniprot id: Q5KAF1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 39 family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Transfers mannose from Dol-P-mannose to Ser or Thr residues on proteins.

214684:CNN01500
gene id: 214684:CNN01500
uniprot id: P0CR24
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the snRNP Sm proteins family. SmF/LSm6 subfamily.
messages: Component of LSm protein complexes, which are involved in RNA processing and may function in a chaperone-like manner, facilitating the efficient association of RNA processing factors with their substrates. Component of the cytoplasmic LSM1-LSM7 complex, which is thought to be involved in mRNA degradation by activating the decapping step in the 5'-to-3' mRNA decay pathway. Component of the nuclear LSM2-LSM8 complex, which is involved in splicing of nuclear mRNAs. LSM2-LSM8 associates with multiple snRNP complexes containing the U6 snRNA (U4/U6 di-snRNP, spliceosomal U4/U6.U5 tri-snRNP, and free U6 snRNP). It binds directly to the 3'-terminal U-tract of U6 snRNA and plays a role in the biogenesis and stability of the U6 snRNP and U4/U6 snRNP complexes. LSM2-LSM8 probably also is involved degradation of nuclear pre-mRNA by targeting them for decapping, and in processing of pre-tRNAs, pre-rRNAs and U3 snoRNA (By similarity).
messages: Component of the heptameric LSM1-LSM7 complex, which consists of LSM1, LSM2, LSM3, LSM4, LSM5, LSM6 and LSM7. Component of the heptameric LSM2-LSM8 complex, which consists of LSM2, LSM3, LSM4, LSM5, LSM6, LSM7 and LSM8. The LSm subunits form a seven-membered ring structure with a doughnut shape (By similarity).
messages: Cytoplasm
messages: Nucleus

214684:CNC02760
gene id: 214684:CNC02760
uniprot id: Q5KKJ8
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

214684:CNE01020
gene id: 214684:CNE01020
uniprot id: P0CN46
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-3 subunit C family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex.
messages: Cytoplasm

214684:CNK00200
gene id: 214684:CNK00200
uniprot id: Q5K9Z1
names: Similarity
messages: Belongs to the PdxS/SNZ family.

214684:CNF00570
gene id: 214684:CNF00570
uniprot id: Q5KFU0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

214684:CNJ00230
gene id: 214684:CNJ00230
uniprot id: Q5KAW5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YAE1 family.
messages: Cytoplasm
messages: Nucleus

214684:CNG03280
gene id: 214684:CNG03280
uniprot id: Q5KDP3
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the rate-limiting step of the oxidative pentose-phosphate pathway, which represents a route for the dissimilation of carbohydrates besides glycolysis. The main function of this enzyme is to provide reducing power (NADPH) and pentose phosphates for fatty acid and nucleic acid synthesis.

214684:CNK01910
gene id: 214684:CNK01910
uniprot id: Q5K9H5
names: Subcellular Location Annotation
messages: Nucleus

214684:CNA04370
gene id: 214684:CNA04370
uniprot id: A0A0S2LIP1
uniprot id: P0CN84
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glutamine synthetase family.
messages: Cytoplasm
messages: Homooctamer.

214684:CNC03300
gene id: 214684:CNC03300
uniprot id: Q5KKE3
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.

214684:CNJ01080
gene id: 214684:CNJ01080
uniprot id: Q5KAN4
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by ADP, AMP, or fructose 2,6-bisphosphate, and allosterically inhibited by ATP or citrate.
messages: Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade "E" sub-subfamily.
messages: Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

214684:CNE00390
gene id: 214684:CNE00390
uniprot id: Q5KHE0
names: Subcellular Location Annotation
messages: Membrane

214684:CNF00680
gene id: 214684:CNF00680
uniprot id: Q5KFS9
names: Subcellular Location Annotation
messages: Membrane

214684:CNE03410
gene id: 214684:CNE03410
uniprot id: P0CQ26
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M76 family.
messages: Has a dual role in the assembly of mitochondrial ATPase. Acts as a protease that removes N-terminal residues of mitochondrial ATPase CF(0) subunit 6 at the intermembrane space side. Also involved in the correct assembly of the membrane-embedded ATPase CF(0) particle, probably mediating association of subunit 6 with the subunit 9 ring (By similarity).
messages: Mitochondrion inner membrane

214684:CNC01750
gene id: 214684:CNC01750
uniprot id: Q5KKV1
names: Similarity
messages: Belongs to the protein kinase superfamily.

214684:CNA02270
gene id: 214684:CNA02270
uniprot id: Q5KPM3
names: Function
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.

214684:CNA07960
gene id: 214684:CNA07960
uniprot id: Q5KN27
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS30 family.

214684:CNI04330
gene id: 214684:CNI04330
uniprot id: Q5KAZ7
names: Similarity
messages: Belongs to the WD repeat CDC20/Fizzy family.

214684:CNC05580
gene id: 214684:CNC05580
uniprot id: Q5KJR9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic release factor 1 family.
messages: Cytoplasm

214684:CNC05370
gene id: 214684:CNC05370
uniprot id: Q5KJU1
names: Subcellular Location Annotation
messages: Nucleus

214684:CNI01790
gene id: 214684:CNI01790
uniprot id: P0CO14
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HEATR1/UTP10 family.
messages: Component of the ribosomal small subunit (SSU) processome.
messages: Involved in nucleolar processing of pre-18S ribosomal RNA. Involved in ribosome biosynthesis (By similarity).
messages: nucleolus

214684:CNL06340
gene id: 214684:CNL06340
uniprot id: Q5K8B0
names: Function
names: Similarity
messages: Belongs to the catalase family.
messages: Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide.
messages: Serves to protect cells from the toxic effects of hydrogen peroxide.

214684:CNE04630
gene id: 214684:CNE04630
uniprot id: Q5KG72
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: Nucleus

214684:CNC04680
gene id: 214684:CNC04680
uniprot id: Q5KK09
names: Similarity
messages: Belongs to the threonine aldolase family.

214684:CNL04300
gene id: 214684:CNL04300
uniprot id: Q5K8W1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ubiquitin conjugation factor E4 family.
messages: Cytoplasm

214684:CNE03150
gene id: 214684:CNE03150
uniprot id: Q5KGL9
names: Similarity
messages: Belongs to the glycosyl hydrolase 5 (cellulase A) family.

214684:CND04410
gene id: 214684:CND04410
uniprot id: Q5KI30
names: Function
names: Similarity
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.

214684:CNB02680
gene id: 214684:CNB02680
uniprot id: Q5KM76
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

214684:CNA04940
gene id: 214684:CNA04940
uniprot id: Q5KNX8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mS29 family.
messages: Mitochondrion

214684:CND03490
gene id: 214684:CND03490
uniprot id: Q5KIC2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

214684:CNC01700
gene id: 214684:CNC01700
uniprot id: Q5KKV6
names: Similarity
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.

214684:CNG03220
gene id: 214684:CNG03220
uniprot id: P0CM16
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Arf family.
messages: GTP-binding protein involved in protein trafficking; may modulate vesicle budding and uncoating within the Golgi apparatus.
messages: Golgi apparatus

214684:CNI00980
gene id: 214684:CNI00980
uniprot id: Q5KBY2
names: Similarity
messages: Belongs to the actin family.

214684:CNH00540
gene id: 214684:CNH00540
uniprot id: Q5KCC5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

214684:CNG00010
gene id: 214684:CNG00010
uniprot id: Q5KEM4
names: Subcellular Location Annotation
messages: Membrane

214684:CNJ02320
gene id: 214684:CNJ02320
uniprot id: P0CP92
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associated with the spliceosome.
messages: Belongs to the cyclophilin-type PPIase family. CWC27 subfamily.
messages: Cytoplasm
messages: Nucleus
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. Involved in pre-mRNA splicing (By similarity).

214684:CNL04550
gene id: 214684:CNL04550
uniprot id: Q5K8T6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CAF1 family.
messages: Nucleus

214684:CNA06840
gene id: 214684:CNA06840
uniprot id: P0CR28
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvB family.
messages: DNA helicase which participates in several chromatin remodeling complexes, including the SWR1 and the INO80 complexes. The SWR1 complex mediates the ATP-dependent exchange of histone H2A for the H2A variant HZT1 leading to transcriptional regulation of selected genes by chromatin remodeling. The INO80 complex remodels chromatin by shifting nucleosomes and is involved in DNA repair. Also involved in pre-rRNA processing (By similarity).
messages: May form heterododecamers with RVB1. Component of the SWR1 chromatin remodeling complex, the INO80 chromatin remodeling complex, and of the R2TP complex (By similarity).
messages: Nucleus

214684:CNA00620
gene id: 214684:CNA00620
uniprot id: Q5KQ34
names: Similarity
messages: Belongs to the protein disulfide isomerase family.

214684:CNJ01960
gene id: 214684:CNJ01960
uniprot id: Q5KAE8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fluoride channel Fluc/FEX (TC 1.A.43) family.
messages: Fluoride channel required for the rapid expulsion of cytoplasmic fluoride.
messages: Membrane

214684:CNC03560
gene id: 214684:CNC03560
uniprot id: P0CR64
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sorting nexin family.
messages: Endomembrane system
messages: Endosome membrane
messages: May be required for cytoplasm to vacuole transport (Cvt) and pexophagy.
messages: The PX domain binds phosphatidylinositol 3-phosphate which is necessary for peripheral membrane localization to the perivacuolar punctate structures.

214684:CNJ02690
gene id: 214684:CNJ02690
uniprot id: Q5KA77
names: Similarity
messages: Belongs to the Tom22 family.

214684:CNK00240
gene id: 214684:CNK00240
uniprot id: Q5K9Y7
names: Similarity
messages: Belongs to the Nudix hydrolase family. DCP2 subfamily.

214684:CNL03990
gene id: 214684:CNL03990
uniprot id: Q5K8Z0
names: Similarity
messages: Belongs to the band 7/mec-2 family.

214684:CNC05020
gene id: 214684:CNC05020
uniprot id: Q5KJX6
names: Similarity
messages: Belongs to the HSBP1 family.

214684:CNE00620
gene id: 214684:CNE00620
uniprot id: Q5KHB4
names: Similarity
messages: Belongs to the WD repeat L(2)GL family.

214684:CND01670
gene id: 214684:CND01670
uniprot id: Q5KIV0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the protein prenyltransferase subunit beta family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the transfer of a geranylgeranyl moiety from geranylgeranyl diphosphate to both cysteines of proteins with the C-terminal sequence -XXCC, -XCXC and -CCXX.

214684:CNI00520
gene id: 214684:CNI00520
uniprot id: P0CN96
names: Function
names: Similarity
names: Subunit
messages: Belongs to the G-alpha family.
messages: G proteins are composed of 3 units; alpha, beta and gamma. The alpha chain contains the guanine nucleotide binding site.
messages: Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. Involved in the mating pathway.

214684:CNJ00680
gene id: 214684:CNJ00680
uniprot id: Q5KAS4
names: Similarity
messages: Belongs to the FGGY kinase family.

214684:CNG02340
gene id: 214684:CNG02340
uniprot id: Q5KDY8
names: Similarity
messages: Belongs to the HARBI1 family.

214684:CNG02860
gene id: 214684:CNG02860
uniprot id: Q5KDT3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase eukaryotic type 2 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Cotranslationally removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val).
messages: Cytoplasm

214684:CNC01610
gene id: 214684:CNC01610
uniprot id: Q5K8H5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H4 family.
messages: Chromosome
messages: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

214684:CNB05550
gene id: 214684:CNB05550
uniprot id: Q5KLE6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NIP7 family.
messages: Interacts with pre-ribosome complex.
messages: Required for proper 27S pre-rRNA processing and 60S ribosome subunit assembly.
messages: nucleolus

214684:CNE02310
gene id: 214684:CNE02310
uniprot id: Q5KGU5
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Rieske iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: Membrane
messages: Mitochondrion inner membrane
messages: The Rieske protein is a high potential 2Fe-2S protein.

214684:CNF02660
gene id: 214684:CNF02660
uniprot id: Q5KF83
names: Similarity
messages: Belongs to the peptidase C19 family.

214684:CND03290
gene id: 214684:CND03290
uniprot id: Q5KIE1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NFYA/HAP2 subunit family.
messages: Component of the sequence-specific heterotrimeric transcription factor (NF-Y) which specifically recognizes a 5'-CCAAT-3' box motif found in the promoters of its target genes.
messages: Heterotrimer.
messages: Nucleus

214684:CNI00550
gene id: 214684:CNI00550
uniprot id: Q5KC23
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M28 family.
messages: Membrane

214684:CND01720
gene id: 214684:CND01720
uniprot id: Q5KIU5
names: Similarity
messages: Belongs to the peptidase S10 family.

214684:CNB00990
gene id: 214684:CNB00990
uniprot id: Q5KMP3
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

214684:CNI00260
gene id: 214684:CNI00260
uniprot id: P0CM84
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COX16 family.
messages: Mitochondrion inner membrane
messages: Required for the assembly of the mitochondrial respiratory chain complex IV (CIV), also known as cytochrome c oxidase. May participate in merging the COX1 and COX2 assembly lines.

214684:CNH00300
gene id: 214684:CNH00300
uniprot id: Q5KCA1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SYF2 family.
messages: Involved in pre-mRNA splicing.
messages: May be part of a spliceosome complex.
messages: Nucleus

214684:CNM01460
gene id: 214684:CNM01460
uniprot id: P0CR82
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TCTP family.
messages: Involved in protein synthesis. Involved in microtubule stabilization (By similarity).
messages: cytoskeleton

214684:CNE04830
gene id: 214684:CNE04830
uniprot id: Q5KG52
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.
messages: cytoskeleton

214684:CNH02650
gene id: 214684:CNH02650
uniprot id: Q5KCY4
names: Cofactor
names: Similarity
messages: Belongs to the chorismate synthase family.
messages: Reduced FMN (FMNH(2)).

214684:CNG04210
gene id: 214684:CNG04210
uniprot id: Q5KDF1
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.

214684:CNI03560
gene id: 214684:CNI03560
uniprot id: P0CN04
names: Activity Regulation
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically inhibited by 3'-phosphoadenosine 5'-phosphosulfate (PAPS).
messages: Catalyzes the first intracellular reaction of sulfate assimilation, forming adenosine-5'-phosphosulfate (APS) from inorganic sulfate and ATP. Plays an important role in sulfate activation as a component of the biosynthesis pathway of sulfur-containing amino acids.
messages: Cytoplasm
messages: Homohexamer. Dimer of trimers.
messages: In the C-terminal section; belongs to the APS kinase family.
messages: In the N-terminal section; belongs to the sulfate adenylyltransferase family.
messages: The adenylyl-sulfate kinase (APS kinase) is non-functional. It is involved in allosteric regulation by PAPS. PAPS binding induces a large rotational rearrangement of domains lowering the substrate affinity of the enzyme.

214684:CNJ03350
gene id: 214684:CNJ03350
uniprot id: Q5KA21
names: Similarity
messages: Belongs to the syntaxin family.

214684:CNE01470
gene id: 214684:CNE01470
uniprot id: Q5KH30
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SGF11 family.
messages: Nucleus

214684:CND02240
gene id: 214684:CND02240
uniprot id: Q5KIP4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IPI1/TEX10 family.
messages: Component of the RIX1 complex required for processing of ITS2 sequences from 35S pre-rRNA.
messages: Component of the RIX1 complex.
messages: Nucleus

214684:CNG00950
gene id: 214684:CNG00950
uniprot id: Q5KEC9
names: Subcellular Location Annotation
messages: Membrane

214684:CNF02480
gene id: 214684:CNF02480
uniprot id: Q5KFA0
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Mitochondrion

214684:CNA00140
gene id: 214684:CNA00140
uniprot id: Q5KQ87
names: Similarity
messages: Belongs to the eukaryotic AdoMetDC family.

214684:CNA07830
gene id: 214684:CNA07830
uniprot id: Q5KN39
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase inhibitor family.
messages: Inhibits the enzyme activity of ATPase.
messages: Mitochondrion

214684:CNJ01450
gene id: 214684:CNJ01450
uniprot id: Q5KAJ7
uniprot id: Q5KAJ8
names: Subcellular Location Annotation
messages: Membrane

214684:CNF00020
gene id: 214684:CNF00020
uniprot id: Q5KFZ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

214684:CNK02530
gene id: 214684:CNK02530
uniprot id: Q5K9B4
names: Similarity
messages: Belongs to the NSRP1 family.

214684:CND03120
gene id: 214684:CND03120
uniprot id: Q5KIF8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RPF2 family.
messages: nucleolus

214684:CNF02750
gene id: 214684:CNF02750
uniprot id: Q5KF73
names: Subcellular Location Annotation
messages: Nucleus

214684:CNF01400
gene id: 214684:CNF01400
uniprot id: Q5KFK9
names: Similarity
messages: Belongs to the amino acid/polyamine transporter 2 family.

214684:CNI00160
gene id: 214684:CNI00160
uniprot id: P0CM38
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATG7 family.
messages: Cytoplasm
messages: E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 and ATG8 for its conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Autophagy is essential for maintenance of amino acid levels and protein synthesis under nitrogen starvation. Required for selective autophagic degradation of the nucleus (nucleophagy) as well as for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production. Plays a role in the regulation of filamentous growth and chronological longevity (By similarity).
messages: Homodimer.
messages: Preautophagosomal structure
messages: The GxGxxG motif is important for the function, possibly through binding with ATP.

214684:CNB00400
gene id: 214684:CNB00400
uniprot id: Q5KMV1
uniprot id: Q5KMV2
names: Subcellular Location Annotation
messages: Membrane

214684:CNF04830
gene id: 214684:CNF04830
uniprot id: Q5KEN6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HMG-CoA reductase family.
messages: Endoplasmic reticulum membrane
messages: Membrane

214684:CNA03380
gene id: 214684:CNA03380
uniprot id: Q5KPB8
names: Subcellular Location Annotation
messages: Membrane

214684:CNC07090
gene id: 214684:CNC07090
uniprot id: Q5KJB8
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

214684:CNE03500
gene id: 214684:CNE03500
uniprot id: Q5KGI4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YIP1 family.
messages: Golgi apparatus membrane
messages: Membrane

214684:CNI02970
gene id: 214684:CNI02970
uniprot id: Q5KBC9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 17 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex.
messages: Nucleus

214684:CNA00860
gene id: 214684:CNA00860
uniprot id: Q5KQ11
names: Similarity
messages: Belongs to the Tango6 family.

214684:CNK02500
gene id: 214684:CNK02500
uniprot id: Q5K9B8
names: Similarity
messages: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. CDC5/Polo subfamily.

214684:CNF00650
gene id: 214684:CNF00650
uniprot id: Q5KFT2
names: Function
messages: Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.

214684:CNF03470
gene id: 214684:CNF03470
uniprot id: Q5KF13
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. FDH subfamily.
messages: Catalyzes the NAD(+)-dependent oxidation of formate to carbon dioxide. Formate oxidation is the final step in the methanol oxidation pathway in methylotrophic microorganisms. Has a role in the detoxification of exogenous formate in non-methylotrophic organisms.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

214684:CNL06670
gene id: 214684:CNL06670
uniprot id: Q5K876
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.

214684:CNC06780
gene id: 214684:CNC06780
uniprot id: Q5KJE9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LU7TM family.
messages: Membrane

214684:CND02900
gene id: 214684:CND02900
uniprot id: Q5KII0
names: Function
messages: Involved in amino sugar synthesis (formation of chitin, supplies the amino sugars of asparagine-linked oligosaccharides of glycoproteins).

214684:CNE04870
gene id: 214684:CNE04870
uniprot id: Q5KG49
names: Function
names: Similarity
messages: Belongs to the proline oxidase family.
messages: Converts proline to delta-1-pyrroline-5-carboxylate.

214684:CNK03330
gene id: 214684:CNK03330
uniprot id: Q5K939
names: Similarity
messages: Belongs to the prephenate/arogenate dehydrogenase family.

214684:CNI04150
gene id: 214684:CNI04150
uniprot id: Q5KB13
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine-cytosine permease (2.A.39) family.
messages: Membrane

214684:CNC03890
gene id: 214684:CNC03890
uniprot id: Q5KK86
names: Similarity
messages: Belongs to the TFIIE alpha subunit family.

214684:CNE02160
gene id: 214684:CNE02160
uniprot id: Q5KGW0
names: Similarity
messages: Belongs to the universal ribosomal protein uS4 family.

214684:CNG00860
gene id: 214684:CNG00860
uniprot id: Q5KED7
names: Similarity
messages: Belongs to the peptidase M16 family.

214684:CNA02810
gene id: 214684:CNA02810
uniprot id: P0CQ42
names: Activity Regulation
names: Similarity
names: Subcellular Location Annotation
messages: Alternates between an inactive form bound to GDP and an active form bound to GTP. Activated by a guanine nucleotide-exchange factor (GEF) and inactivated by a GTPase-activating protein (GAP).
messages: Belongs to the small GTPase superfamily. Ras family.
messages: Cell membrane

214684:CNF03650
gene id: 214684:CNF03650
uniprot id: Q5KEZ6
names: Function
names: Similarity
messages: Belongs to the diphthine synthase family.
messages: In the N-terminal section; belongs to the precorrin methyltransferase family.
messages: S-adenosyl-L-methionine-dependent methyltransferase that catalyzes four methylations of the modified target histidine residue in translation elongation factor 2 (EF-2), to form an intermediate called diphthine methyl ester. The four successive methylation reactions represent the second step of diphthamide biosynthesis.

214684:CNB02810
gene id: 214684:CNB02810
uniprot id: Q5KM62
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.

214684:CND03100
gene id: 214684:CND03100
uniprot id: P0CN68
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FES1 family.
messages: Cytoplasm
messages: Functions as a nucleotide exchange factor (NEF) for Hsp70 chaperones which accelerates the release of ADP. Required for fully efficient Hsp70-mediated folding of proteins (By similarity).

214684:CNA06490
gene id: 214684:CNA06490
uniprot id: Q5KNH3
names: Similarity
messages: Belongs to the TCF25 family.

214684:CNG04420
gene id: 214684:CNG04420
uniprot id: Q5KDD1
names: Similarity
messages: Belongs to the glycosyltransferase group 1 family.

214684:CNE00140
gene id: 214684:CNE00140
uniprot id: Q5KHG5
names: Similarity
names: Subunit
messages: Belongs to the transketolase family.
messages: Homodimer.

214684:CNE04600
gene id: 214684:CNE04600
uniprot id: Q5KG75
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M1 family.
messages: Binds 1 zinc ion per subunit.

214684:CNJ02060
gene id: 214684:CNJ02060
uniprot id: Q5KAD7
names: Similarity
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.

214684:CNC00990
gene id: 214684:CNC00990
uniprot id: Q5KL26
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic ATPase B chain family.
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. In yeast, the dimeric form of ATP synthase consists of 17 polypeptides: alpha, beta, gamma, delta, epsilon, 4 (B), 5 (OSCP), 6 (A), 8, 9 (C), d, E (Tim11), f, g, h, i/j and k.
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain and the peripheric stalk, which acts as a stator to hold the catalytic alpha(3)beta(3) subcomplex and subunit a/ATP6 static relative to the rotary elements.
messages: Mitochondrion
messages: Mitochondrion inner membrane

214684:CNB01060
gene id: 214684:CNB01060
uniprot id: P0CQ84
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent RNA helicase involved in 40S ribosomal subunit biogenesis. Required for the processing and cleavage of 35S pre-rRNA at sites A0, A1, and A2, leading to mature 18S rRNA.
messages: Associates in the nucleolus with the 60S and pre-60S ribosomal subunits.
messages: Belongs to the DEAD box helicase family. DDX18/HAS1 subfamily.
messages: The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.
messages: nucleolus

214684:CND01800
gene id: 214684:CND01800
uniprot id: Q5KIT7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane

214684:CNL06580
gene id: 214684:CNL06580
uniprot id: Q5K887
names: Subcellular Location Annotation
messages: nuclear pore complex

214684:CNC00710
gene id: 214684:CNC00710
uniprot id: Q5KL55
names: Subcellular Location Annotation
messages: Membrane

214684:CNL03830
gene id: 214684:CNL03830
uniprot id: Q5K906
uniprot id: Q5K907
names: Function
names: Similarity
messages: Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration.
messages: Belongs to the adaptor complexes large subunit family.

214684:CNF03720
gene id: 214684:CNF03720
uniprot id: Q5KEY9
names: Similarity
messages: Belongs to the cytochrome P450 family.

214684:CNN00540
gene id: 214684:CNN00540
uniprot id: Q5K7A4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferroportin (FP) (TC 2.A.100) family. SLC40A subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: May be involved in iron transport and iron homeostasis.
messages: Membrane

214684:CNN02130
gene id: 214684:CNN02130
uniprot id: Q5K6V6
names: Function
names: Similarity
messages: ATP dependent phosphorylation of adenosine and other related nucleoside analogs to monophosphate derivatives.
messages: Belongs to the carbohydrate kinase PfkB family.

214684:CNH01120
gene id: 214684:CNH01120
uniprot id: Q5KCI3
names: Similarity
messages: Belongs to the peptidase S8 family. Furin subfamily.

214684:CNE01870
gene id: 214684:CNE01870
uniprot id: Q5KGY9
names: Similarity
messages: Belongs to the SUA5 family.

214684:CNC03130
gene id: 214684:CNC03130
uniprot id: Q5KKG0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TFB1 family.
messages: Nucleus

214684:CND02250
gene id: 214684:CND02250
uniprot id: Q5KIP3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. CPSF2/YSH1 subfamily.
messages: Nucleus

214684:CNA03250
gene id: 214684:CNA03250
uniprot id: Q5KPC9
names: Similarity
messages: Belongs to the sirtuin family. Class I subfamily.

214684:CND05390
gene id: 214684:CND05390
uniprot id: Q5KHT1
names: Similarity
messages: Belongs to the VPS26 family.

214684:CNF04730
gene id: 214684:CNF04730
uniprot id: P0CO24
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NHP6 family.
messages: Chromosome
messages: DNA-binding protein that induces severe bending of DNA. Required for DNA-binding by the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. Also augments the fidelity of transcription by RNA polymerase III independently of any role in the FACT complex (By similarity).
messages: Nucleus
messages: Weakly associates with the stable SPT16-POB3 heterodimer to form the FACT complex.

214684:CNM00110
gene id: 214684:CNM00110
uniprot id: Q5K850
names: Function
names: Similarity
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of mitochondrial tRNA(Lys), tRNA(Glu) and tRNA(Gln). Required for the formation of 5-taurinomethyl-2-thiouridine (tm5s2U) of mitochondrial tRNA(Lys), tRNA(Glu), and tRNA(Gln) at the wobble position. ATP is required to activate the C2 atom of the wobble base.

214684:CNC05850
gene id: 214684:CNC05850
uniprot id: Q5KJP0
names: Function
names: Similarity
messages: Belongs to the flavokinase family.
messages: Catalyzes the phosphorylation of riboflavin (vitamin B2) to form flavin mononucleotide (FMN) coenzyme.

214684:CNI00050
gene id: 214684:CNI00050
uniprot id: P0CN28
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Dus family. Dus3 subfamily.
messages: Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs. Specifically modifies U47 in cytoplasmic tRNAs (By similarity). Catalyzes the synthesis of dihydrouridine in some mRNAs, thereby affecting their translation (By similarity).
messages: Cytoplasm
messages: Nucleus

214684:CNC00920
gene id: 214684:CNC00920
uniprot id: Q5KL32
names: Similarity
names: Subunit
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
messages: Homohexamer.

214684:CNF00350
gene id: 214684:CNF00350
uniprot id: Q5KFW3
names: Subcellular Location Annotation
messages: Membrane

214684:CNH00990
gene id: 214684:CNH00990
uniprot id: Q5KCH2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

214684:CNB00120
gene id: 214684:CNB00120
uniprot id: Q5KMX8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HSF family.
messages: DNA-binding transcription factor that specifically binds heat shock promoter elements (HSE) and activates transcription (PubMed:17040492). Together with its coregulator SSA1, activates expression of laccase LAC1 during glucose starvation (PubMed:17040492).
messages: Homotrimer (By similarity). Homotrimerization increases the affinity of HSF1 to DNA (By similarity). Interacts with transcriptional coregulator SSA1 on chromatin (PubMed:17040492).
messages: Nucleus

214684:CNE02470
gene id: 214684:CNE02470
uniprot id: Q5KGS9
names: Similarity
messages: Belongs to the patched family.

214684:CNC01890
gene id: 214684:CNC01890
uniprot id: Q5KKT7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fungal Na(+)/H(+) exchanger family.
messages: Membrane

214684:CNI03460
gene id: 214684:CNI03460
uniprot id: Q5KB80
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CASP family.
messages: Golgi apparatus membrane
messages: Membrane

214684:CNH02040
gene id: 214684:CNH02040
uniprot id: Q5KCS1
names: Function
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL8 family.
messages: Component of the ribosome.

214684:CNA05480
gene id: 214684:CNA05480
uniprot id: Q5KNS4
names: Similarity
messages: Belongs to the ATP-dependent DNA ligase family.

214684:CNC02450
gene id: 214684:CNC02450
uniprot id: Q5KKN1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

214684:CNF02530
gene id: 214684:CNF02530
uniprot id: Q5KF96
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Peroxisome

214684:CNG01920
gene id: 214684:CNG01920
uniprot id: Q5KE31
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

214684:CNG01940
gene id: 214684:CNG01940
uniprot id: P0CR46
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHE9 family.
messages: Homooligomer.
messages: Mitochondrion inner membrane
messages: Required for the maintenance of the structure of the mitochondrial inner membrane. Involved in mitochondrial morphology. Causes growth arrest when highly overexpressed (By similarity).

214684:CNL04280
gene id: 214684:CNL04280
uniprot id: Q5K8W3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFA8 subunit family.
messages: Mitochondrion inner membrane

214684:CNB00480
gene id: 214684:CNB00480
uniprot id: Q5KMU3
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.

214684:CNJ00410
gene id: 214684:CNJ00410
uniprot id: Q5KAU8
names: Function
names: Similarity
messages: Belongs to the SHMT family.
messages: Interconversion of serine and glycine.

214684:CNC01330
gene id: 214684:CNC01330
uniprot id: Q5KKZ4
names: Subcellular Location Annotation
messages: Membrane

214684:CNJ03290
gene id: 214684:CNJ03290
uniprot id: Q5KA27
names: Similarity
messages: Belongs to the AAA ATPase family.

214684:CNL05120
gene id: 214684:CNL05120
uniprot id: Q5K8M7
names: Similarity
messages: Belongs to the universal ribosomal protein uS13 family.

214684:CND01210
gene id: 214684:CND01210
uniprot id: Q5KIZ4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the COQ7 family.
messages: Binds 2 iron ions per subunit.
messages: Catalyzes the hydroxylation of 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) during ubiquinone biosynthesis. Has also a structural role in the COQ enzyme complex, stabilizing other COQ polypeptides.
messages: Component of a multi-subunit COQ enzyme complex, composed of at least COQ3, COQ4, COQ5, COQ6, COQ7 and COQ9.
messages: Mitochondrion inner membrane

214684:CNJ03110
gene id: 214684:CNJ03110
uniprot id: Q5KA46
names: Similarity
messages: Belongs to the universal ribosomal protein uS13 family.

214684:CNE00700
gene id: 214684:CNE00700
uniprot id: Q5KHA6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MRE11/RAD32 family.
messages: Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing.
messages: Nucleus

214684:CNC03610
gene id: 214684:CNC03610
uniprot id: Q5KKB4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TCP-1 chaperonin family.
messages: Cytoplasm

214684:CNF02850
gene id: 214684:CNF02850
uniprot id: Q5KF64
names: Subcellular Location Annotation
messages: Nucleus

214684:CNB05220
gene id: 214684:CNB05220
uniprot id: Q5KLH8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NifU family.
messages: Mitochondrion matrix
messages: Scaffold protein for the de novo synthesis of iron-sulfur (Fe-S) clusters within mitochondria, which is required for maturation of both mitochondrial and cytoplasmic [2Fe-2S] and [4Fe-4S] proteins.

214684:CNB05650
gene id: 214684:CNB05650
uniprot id: Q5KLD6
names: Similarity
messages: Belongs to the polyprenol kinase family.

214684:CND06230
gene id: 214684:CND06230
uniprot id: Q5KHJ8
names: Subcellular Location Annotation
messages: cytosol

214684:CND05090
gene id: 214684:CND05090
uniprot id: Q5KHW3
names: Similarity
messages: Belongs to the helicase family. SKI2 subfamily.

214684:CNC03850
gene id: 214684:CNC03850
uniprot id: Q5KK90
names: Similarity
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 2 subfamily.
messages: Tetramer of two alpha and two beta subunits.

214684:CNA07200
gene id: 214684:CNA07200
uniprot id: P0CQ96
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: ATP-binding RNA helicase involved in transcription elongation and required for the export of mRNA out of the nucleus. SUB2 also plays a role in pre-mRNA splicing and spliceosome assembly. May be involved in rDNA and telomeric silencing, and maintenance of genome integrity (By similarity).
messages: Belongs to the DEAD box helicase family. DECD subfamily.
messages: Nucleus
messages: The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.

214684:CND04070
gene id: 214684:CND04070
uniprot id: Q5KI64
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I 51 kDa subunit family.
messages: Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor. Essential for the catalytic activity and assembly of complex I.
messages: Mitochondrion inner membrane

214684:CNE00330
gene id: 214684:CNE00330
uniprot id: Q5KHE7
names: Similarity
messages: Belongs to the DAMOX/DASOX family.

214684:CNI04170
gene id: 214684:CNI04170
uniprot id: Q5KB11
names: Similarity
messages: Belongs to the ATP-dependent DNA ligase family.

214684:CNH02740
gene id: 214684:CNH02740
uniprot id: Q5KCZ3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UQCR10/QCR9 family.
messages: Component of the ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII), a multisubunit enzyme composed of 3 respiratory subunits cytochrome b, cytochrome c1 and Rieske protein, 2 core protein subunits, and additional low-molecular weight protein subunits.
messages: Component of the ubiquinol-cytochrome c oxidoreductase, a multisubunit transmembrane complex that is part of the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. The cytochrome b-c1 complex catalyzes electron transfer from ubiquinol to cytochrome c, linking this redox reaction to translocation of protons across the mitochondrial inner membrane, with protons being carried across the membrane as hydrogens on the quinol. In the process called Q cycle, 2 protons are consumed from the matrix, 4 protons are released into the intermembrane space and 2 electrons are passed to cytochrome c.
messages: Membrane
messages: Mitochondrion inner membrane

214684:CNF03530
gene id: 214684:CNF03530
uniprot id: Q5KF07
names: Function
names: Similarity
messages: Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis.
messages: Belongs to the glycogen phosphorylase family.

214684:CNA00300
gene id: 214684:CNA00300
uniprot id: Q5KQ65
names: Similarity
messages: Belongs to the cytochrome P450 family.

214684:CNG01390
gene id: 214684:CNG01390
uniprot id: Q5KE84
names: Similarity
messages: Belongs to the eIF-2B alpha/beta/delta subunits family.

214684:CNA04780
gene id: 214684:CNA04780
uniprot id: Q5KNZ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

214684:CNI02460
gene id: 214684:CNI02460
uniprot id: Q5KBI1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TCP-1 chaperonin family.
messages: Cytoplasm

214684:CNC02730
gene id: 214684:CNC02730
uniprot id: Q5KKK1
names: Similarity
messages: Belongs to the beclin family.

214684:CNN01430
gene id: 214684:CNN01430
uniprot id: Q5K719
names: Similarity
messages: Belongs to the PP2C family.

214684:CNF03260
gene id: 214684:CNF03260
uniprot id: Q5KF31
names: Subcellular Location Annotation
messages: Mitochondrion outer membrane

214684:CNC04460
gene id: 214684:CNC04460
uniprot id: Q5KK29
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily.

214684:CNC05860
gene id: 214684:CNC05860
uniprot id: Q5KJN9
names: Subcellular Location Annotation
messages: Membrane

214684:CNL05600
gene id: 214684:CNL05600
uniprot id: Q5K8I1
names: Function
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.

214684:CNN00580
gene id: 214684:CNN00580
uniprot id: Q5K7A0
names: Similarity
messages: Belongs to the iron/ascorbate-dependent oxidoreductase family.

214684:CNE00730
gene id: 214684:CNE00730
uniprot id: Q5KHA3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the very long-chain fatty acids dehydratase HACD family.
messages: Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

214684:CNC04570
gene id: 214684:CNC04570
uniprot id: Q5KK19
names: Similarity
messages: Belongs to the cytochrome P450 family.

214684:CNH03590
gene id: 214684:CNH03590
uniprot id: Q5KD78
names: Function
messages: Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase.

214684:CNE01650
gene id: 214684:CNE01650
uniprot id: Q5KH10
names: Similarity
messages: Belongs to the eukaryotic-type primase small subunit family.

214684:CNK00280
gene id: 214684:CNK00280
uniprot id: Q5K9Y3
names: Similarity
messages: Belongs to the BPG-independent phosphoglycerate mutase family.

214684:CNF02610
gene id: 214684:CNF02610
uniprot id: Q5KF88
names: Similarity
messages: Belongs to the BTG family.

214684:CNE00070
gene id: 214684:CNE00070
uniprot id: Q5KG14
names: Similarity
messages: Belongs to the TMA16 family.

214684:CND04690
gene id: 214684:CND04690
uniprot id: Q5KI02
names: Subcellular Location Annotation
messages: Membrane

214684:CNA03730
gene id: 214684:CNA03730
uniprot id: Q5KP95
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1B family.
messages: Component of the proteasome complex.
messages: Component of the proteasome, a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.
messages: Cytoplasm
messages: Nucleus

214684:CNC03660
gene id: 214684:CNC03660
uniprot id: P0CQ18
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.
messages: Cleaves proteins, imported into the mitochondrion, to their mature size. While most mitochondrial precursor proteins are processed to the mature form in one step by mitochondrial processing peptidase (MPP), the sequential cleavage by MIP of an octapeptide after initial processing by MPP is a required step for a subgroup of nuclear-encoded precursor proteins destined for the matrix or the inner membrane (By similarity).
messages: Mitochondrion matrix

214684:CNE01790
gene id: 214684:CNE01790
uniprot id: Q5KGZ7
names: Similarity
messages: Belongs to the CWC16 family.

214684:CNN01680
gene id: 214684:CNN01680
uniprot id: Q5K6Z5
uniprot id: Q5K6Z6
names: Function
names: Similarity
messages: Belongs to the heat shock protein 70 family.
messages: Probably plays a role in facilitating the assembly of multimeric protein complexes inside the ER. Is required for secretory polypeptide translocation. May physically associate with SEC63 protein in the endoplasmic reticulum and this interaction may be regulated by ATP hydrolysis.

214684:CNB00790
gene id: 214684:CNB00790
uniprot id: Q5KMR2
names: Similarity
messages: Belongs to the RAD52 family.

214684:CNC06940
gene id: 214684:CNC06940
uniprot id: Q5KJD4
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL15 family.

214684:CNA02850
gene id: 214684:CNA02850
uniprot id: P0CQ66
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNF2/RAD54 helicase family.
messages: Cytoplasm
messages: Nucleus
messages: Probable helicase, member of the UBC2/RAD6 epistasis group. Functions with DNA repair protein RAD18 in error-free postreplication DNA repair. Involved in the maintenance of wild-type rates of instability of simple repetitive sequences such as poly(GT) repeats. Seems to be involved in maintaining a balance which acts in favor of error-prone non-homologous joining during DNA double-strand breaks repairs (By similarity).

214684:CNJ02970
gene id: 214684:CNJ02970
uniprot id: Q5KA58
names: Similarity
messages: Belongs to the type-B carboxylesterase/lipase family.

214684:CNH01620
gene id: 214684:CNH01620
uniprot id: P0CO22
names: Function
names: Similarity
names: Subunit
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Homotrimer.
messages: Imidazole glycerol-phosphate dehydratase required for histidine biosynthesis.

214684:CNA07480
gene id: 214684:CNA07480
uniprot id: Q5KN74
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA mismatch repair MutS family.
messages: Component of the post-replicative DNA mismatch repair system (MMR).
messages: Nucleus

214684:CNB04160
gene id: 214684:CNB04160
uniprot id: Q5KLT2
names: Similarity
messages: Belongs to the BolA/IbaG family.

214684:CNA05430
gene id: 214684:CNA05430
uniprot id: P0CO06
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HAT1 family.
messages: Catalytic component of the histone acetylase B (HAT-B) complex. Acetylates 'Lys-12' of histone H4 which is required for telomeric silencing. Has intrinsic substrate specificity that modifies lysine in recognition sequence GXGKXG. Involved in DNA double-strand break repair (By similarity).
messages: Component of the HAT-B complex composed of at least HAT1 and HAT2. The HAT-B complex binds to histone H4 tail (By similarity).
messages: Cytoplasm
messages: Nucleus

214684:CNE00310
gene id: 214684:CNE00310
uniprot id: Q5KHE9
names: Function
names: Similarity
messages: Belongs to the KptA/TPT1 family.
messages: Catalyzes the last step of tRNA splicing, the transfer of the splice junction 2'-phosphate from ligated tRNA to NAD to produce ADP-ribose 1''-2'' cyclic phosphate.

214684:CNG00910
gene id: 214684:CNG00910
uniprot id: Q5KED2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Membrane

214684:CNC06260
gene id: 214684:CNC06260
uniprot id: Q5KJK1
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

214684:CND05060
gene id: 214684:CND05060
uniprot id: P0CR18
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ribose 5-phosphate isomerase family.
messages: Cytoplasm

214684:CNB01690
gene id: 214684:CNB01690
uniprot id: Q5KMH4
names: Subcellular Location Annotation
messages: Membrane

214684:CND06110
gene id: 214684:CND06110
uniprot id: Q5KHK9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the squalene monooxygenase family.
messages: Catalyzes the stereospecific oxidation of squalene to (S)-2,3-epoxysqualene, and is considered to be a rate-limiting enzyme in steroid biosynthesis.
messages: Endoplasmic reticulum membrane
messages: Microsome membrane

214684:CND01280
gene id: 214684:CND01280
uniprot id: Q5KIY7
names: Similarity
messages: Belongs to the non-repetitive/WGA-negative nucleoporin family.

214684:CNH02210
gene id: 214684:CNH02210
uniprot id: Q5KCT8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PIGC family.
messages: Membrane

214684:CNF03750
gene id: 214684:CNF03750
uniprot id: Q5KEY6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic RPC34/RPC39 RNA polymerase subunit family.
messages: Nucleus

214684:CNG02370
gene id: 214684:CNG02370
uniprot id: P0CS52
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the WD repeat TRM82 family.
messages: Forms a heterodimer with the catalytic subunit TRM8.
messages: Nucleus
messages: Required for the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. In the complex, it is required to stabilize and induce conformational changes of the catalytic subunit.

214684:CNC02520
gene id: 214684:CNC02520
uniprot id: Q5KKM4
names: Similarity
messages: Belongs to the heat shock protein 70 family.

214684:CNI00320
gene id: 214684:CNI00320
uniprot id: Q5KC42
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
messages: Cytoplasm
messages: Homotetramer.

214684:CNE03630
gene id: 214684:CNE03630
uniprot id: Q5KGH1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Cytoplasm
messages: Endoplasmic reticulum
messages: Fungal signal recognition particle consists of a 7S RNA molecule (scR1) and at least six protein subunits: srp72, srp68, srp54, sec65, srp21 and srp14.
messages: Signal-recognition-particle (SRP) assembly has a crucial role in targeting secretory proteins to the rough endoplasmic reticulum (ER) membrane. SRP is required for the cotranslational protein translocation for ER import and preferentially recognizes strongly hydrophobic signal sequences. It is involved in targeting the nascent chain-ribosome (RNC) complex to the ER and is proposed to participate in the arrest of nascent chain elongation during membrane targeting. SRP54 binds to the signal sequence of presecretory protein when they emerge from the ribosomes. SRP54 interacts with the scR1 RNA and mediates the association of the resulting SRP-RNC complex with the signal recognition particle receptor (SR) via its alpha subunit SRP101. Both, SRP54 and SRP101, are locked in their GTP bound forms in the SRP-RNC-SR complex, which dissociates upon transferring the signal sequence to the protein-conducting channel (translocon). After signal sequence transfer, SRP54 and SRP101 act as reciprocal GTPase-activating proteins (GAPs), thereby resolving their association.
messages: The M domain binds the 7SL RNA and the signal sequence of presecretory proteins.
messages: The NG domain, also named G domain, is a special guanosine triphosphatase (GTPase) domain, which binds GTP and forms a guanosine 5'-triphosphate (GTP)-dependent complex with a homologous NG domain in the SRP receptor subunit srp101. The two NG domains undergo cooperative rearrangements upon their assembly, which culminate in the reciprocal activation of the GTPase activity of one another. SRP receptor compaction upon binding with cargo-loaded SRP and GTPase rearrangement drive SRP-mediated cotranslational protein translocation into the ER.

214684:CNI02590
gene id: 214684:CNI02590
uniprot id: Q5KBG8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFB3 subunit family.
messages: Mitochondrion inner membrane

214684:CNH03470
gene id: 214684:CNH03470
uniprot id: Q5KD67
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.
messages: Membrane

214684:CNH02870
gene id: 214684:CNH02870
uniprot id: Q5KD06
names: Similarity
messages: Belongs to the peptidase M28 family.

214684:CNK02880
gene id: 214684:CNK02880
uniprot id: Q5K981
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

214684:CNN00220
gene id: 214684:CNN00220
uniprot id: Q5K7D6
names: Similarity
messages: Belongs to the glutathione peroxidase family.

214684:CNE00120
gene id: 214684:CNE00120
uniprot id: Q5KHG7
names: Similarity
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.

214684:CNH00490
gene id: 214684:CNH00490
uniprot id: Q5KCB9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

214684:CND01160
gene id: 214684:CND01160
uniprot id: Q5KIZ9
names: Subcellular Location Annotation
messages: Cytoplasm

214684:CNB03050
gene id: 214684:CNB03050
uniprot id: Q5KM44
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the snRNP core protein family.
messages: Nucleus
messages: cytosol

214684:CNE03610
gene id: 214684:CNE03610
uniprot id: Q5KGH3
names: Similarity
messages: Belongs to the PPP phosphatase family.

214684:CNF04190
gene id: 214684:CNF04190
uniprot id: Q5KEU7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAA ATPase family.
messages: Cytoplasm
messages: Required for vesicle-mediated transport. Catalyzes the fusion of transport vesicles within the Golgi cisternae. Is also required for transport from the endoplasmic reticulum to the Golgi stack. Seems to function as a fusion protein required for the delivery of cargo proteins to all compartments of the Golgi stack independent of vesicle origin.

214684:CNA05110
gene id: 214684:CNA05110
uniprot id: Q5KNW1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tellurite-resistance/dicarboxylate transporter (TDT) family.
messages: Membrane

214684:CNC01420
gene id: 214684:CNC01420
uniprot id: Q5KKY4
names: Similarity
messages: Belongs to the TRM112 family.

214684:CNF02020
gene id: 214684:CNF02020
uniprot id: Q5KFE5
names: Subcellular Location Annotation
messages: Nucleus

214684:CND01590
gene id: 214684:CND01590
uniprot id: Q5KIV7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IMPACT family.
messages: Cytoplasm

214684:CNI02170
gene id: 214684:CNI02170
uniprot id: Q5KBL1
names: Subcellular Location Annotation
names: Subunit
messages: Component of the mitochondrial large ribosomal subunit.
messages: Mitochondrion

214684:CNB02480
gene id: 214684:CNB02480
uniprot id: Q5KM94
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycosyltransferase 2 family.
messages: Component of the dolichol-phosphate mannose (DPM) synthase complex.
messages: Endoplasmic reticulum
messages: Transfers mannose from GDP-mannose to dolichol monophosphate to form dolichol phosphate mannose (Dol-P-Man) which is the mannosyl donor in pathways leading to N-glycosylation, glycosyl phosphatidylinositol membrane anchoring, and O-mannosylation of proteins.

214684:CNK03000
gene id: 214684:CNK03000
uniprot id: P0CM82
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the COQ4 family.
messages: Component of a multi-subunit COQ enzyme complex, composed of at least COQ3, COQ4, COQ5, COQ6, COQ7 and COQ9.
messages: Component of the coenzyme Q biosynthetic pathway. May play a role in organizing a multi-subunit COQ enzyme complex required for coenzyme Q biosynthesis. Required for steady-state levels of other COQ polypeptides.
messages: Mitochondrion inner membrane
messages: This protein may be expected to contain an N-terminal transit peptide but none has been predicted.

214684:CNE04690
gene id: 214684:CNE04690
uniprot id: Q5KG66
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GDT1 family.
messages: Membrane

214684:CNI00670
gene id: 214684:CNI00670
uniprot id: Q5KC13
names: Similarity
messages: Belongs to the tRNA pseudouridine synthase TruA family.

214684:CNH03570
gene id: 214684:CNH03570
uniprot id: Q5KD76
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acireductone dioxygenase (ARD) family.
messages: Binds either 1 Fe or Ni cation per monomer. Iron-binding promotes an acireductone dioxygenase reaction producing 2-keto-4-methylthiobutyrate, while nickel-binding promotes an acireductone dioxygenase reaction producing 3-(methylsulfanyl)propanoate.
messages: Catalyzes 2 different reactions between oxygen and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4-methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway.
messages: Cytoplasm
messages: Nucleus

214684:CNM01130
gene id: 214684:CNM01130
uniprot id: Q5K7V7
names: Similarity
messages: Belongs to the WD repeat LST8 family.

214684:CNF02370
gene id: 214684:CNF02370
uniprot id: Q5KFB0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the protein prenyltransferase subunit beta family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the transfer of a farnesyl moiety from farnesyl diphosphate to a cysteine at the fourth position from the C-terminus of several proteins. The beta subunit is responsible for peptide-binding.
messages: Heterodimer of an alpha and a beta subunit.

214684:CNB01710
gene id: 214684:CNB01710
uniprot id: Q5KMH2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAPP small subunits family. BET3 subfamily.
messages: Endoplasmic reticulum
messages: Part of the multisubunit TRAPP (transport protein particle) complex.
messages: cis-Golgi network

214684:CNE04430
gene id: 214684:CNE04430
uniprot id: P0CN36
names: Similarity
messages: Belongs to the EFR3 family.

214684:CNE04390
gene id: 214684:CNE04390
uniprot id: Q5KG96
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peroxin-16 family.
messages: Peroxisome membrane

214684:CND02120
gene id: 214684:CND02120
uniprot id: Q5KIQ6
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

214684:CNA01060
gene id: 214684:CNA01060
uniprot id: Q5KPZ1
names: Similarity
messages: Belongs to the universal ribosomal protein uS3 family.

214684:CNL05720
gene id: 214684:CNL05720
uniprot id: Q5K8H0
names: Similarity
messages: Belongs to the MGR2 family.

214684:CNM02270
gene id: 214684:CNM02270
uniprot id: Q5K7J0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFA5 subunit family.
messages: Mitochondrion inner membrane

214684:CNC03180
gene id: 214684:CNC03180
uniprot id: Q5KKF5
names: Domain
names: Function
names: Similarity
messages: Belongs to the DEAD box helicase family.
messages: RNA helicase.
messages: The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.

214684:CNC04410
gene id: 214684:CNC04410
uniprot id: Q5KK34
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Arginine methyltransferase involved in the assembly or stability of mitochondrial NADH:ubiquinone oxidoreductase complex (complex I).
messages: Belongs to the NDUFAF7 family.
messages: Mitochondrion

214684:CNF03300
gene id: 214684:CNF03300
uniprot id: Q5KF28
names: Subcellular Location Annotation
messages: Nucleus

214684:CNC07130
gene id: 214684:CNC07130
uniprot id: Q5KJB4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC35F solute transporter family.
messages: Membrane

214684:CNL06650
gene id: 214684:CNL06650
uniprot id: Q5K878
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRA1 family.
messages: Membrane

214684:CNG01470
gene id: 214684:CNG01470
uniprot id: Q5KE76
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Tom20 family.
messages: Membrane

214684:CNB04500
gene id: 214684:CNB04500
uniprot id: Q5KLQ0
names: Similarity
messages: Belongs to the universal ribosomal protein uL10 family.

214684:CNN01140
gene id: 214684:CNN01140
uniprot id: Q5K745
names: Similarity
messages: Belongs to the cullin family.

214684:CNC02700
gene id: 214684:CNC02700
uniprot id: Q5KKK5
names: Subcellular Location Annotation
messages: Membrane
messages: Mitochondrion inner membrane

214684:CNG00250
gene id: 214684:CNG00250
uniprot id: P0CM46
names: Function
names: Similarity
names: Subunit
messages: Belongs to the palA/RIM20 family.
messages: Interacts with RIM101 by binding to its YPX[LI] motif.
messages: Required for the proteolytic cleavage of the transcription factor RIM101 in response to alkaline ambient pH. May act as a scaffold protein that recruits the calpain-like protease RIM13 via VPS32 to its substrate RIM101 (By similarity).

214684:CNL04370
gene id: 214684:CNL04370
uniprot id: Q5K8V4
names: Subcellular Location Annotation
messages: Membrane

214684:CNI00240
gene id: 214684:CNI00240
uniprot id: Q5KC50
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

214684:CND03060
gene id: 214684:CND03060
uniprot id: Q5KIG4
names: Similarity
messages: In the C-terminal section; belongs to the eukaryotic ribosomal protein eS31 family.
messages: In the N-terminal section; belongs to the ubiquitin family.

214684:CNA03580
gene id: 214684:CNA03580
uniprot id: Q5KP99
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Catalyzes an early step in the biosynthesis of tetrapyrroles. Binds two molecules of 5-aminolevulinate per subunit, each at a distinct site, and catalyzes their condensation to form porphobilinogen.
messages: Homooctamer.

214684:CNH02910
gene id: 214684:CNH02910
uniprot id: Q5KD10
names: Similarity
messages: Belongs to the malate synthase family.

214684:CND05910
gene id: 214684:CND05910
uniprot id: Q5KHN0
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL22 family.

214684:CNG03490
gene id: 214684:CNG03490
uniprot id: Q5KDL9
names: Similarity
names: Subunit
messages: Belongs to the LDH/MDH superfamily. MDH type 1 family.
messages: Homodimer.

214684:CNA06730
gene id: 214684:CNA06730
uniprot id: P0CO10
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associated with the spliceosome.
messages: Belongs to the crooked-neck family.
messages: Involved in pre-mRNA splicing and cell cycle progression. Required for the spliceosome assembly and initiation of the DNA replication (By similarity).
messages: Nucleus

214684:CNJ00110
gene id: 214684:CNJ00110
uniprot id: Q5KAX6
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family.
messages: Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 18S rRNA in the 40S particle.

214684:CNI01680
gene id: 214684:CNI01680
uniprot id: Q5KBR3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OB-RGRP/VPS55 family.
messages: Membrane

214684:CNI04380
gene id: 214684:CNI04380
uniprot id: Q5KAZ1
names: Similarity
messages: Belongs to the GST superfamily.

214684:CND02130
gene id: 214684:CND02130
uniprot id: Q5KIQ5
names: Similarity
messages: Belongs to the EAF family.

214684:CNG02950
gene id: 214684:CNG02950
uniprot id: Q5KDS4
names: Similarity
messages: Belongs to the DapA family.

214684:CNL05910
gene id: 214684:CNL05910
uniprot id: Q5K8F2
names: Similarity
messages: Belongs to the flavin monoamine oxidase family.

214684:CNB02730
gene id: 214684:CNB02730
uniprot id: Q5KM70
names: Subcellular Location Annotation
messages: Membrane

214684:CNL04870
gene id: 214684:CNL04870
uniprot id: Q5K8Q3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family.
messages: Catalyzes the hydrolysis of ATP coupled with the transport of calcium.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

214684:CNC02440
gene id: 214684:CNC02440
uniprot id: Q5KKN2
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.

214684:CNA01050
gene id: 214684:CNA01050
uniprot id: Q5KPZ2
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

214684:CNG02470
gene id: 214684:CNG02470
uniprot id: Q5KDX5
names: Similarity
messages: Belongs to the activator 1 small subunits family.

214684:CNN01460
gene id: 214684:CNN01460
uniprot id: Q5K716
names: Similarity
messages: Belongs to the acetolactate synthase small subunit family.

214684:CNC02120
gene id: 214684:CNC02120
uniprot id: Q5KKR3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Endoplasmic reticulum membrane
messages: Membrane

214684:CNG03020
gene id: 214684:CNG03020
uniprot id: Q5KDR8
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

214684:CNE02620
gene id: 214684:CNE02620
uniprot id: Q5KGR5
names: Function
names: Similarity
messages: Belongs to the BCKDHA family.
messages: The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3).

214684:CNN02120
gene id: 214684:CNN02120
uniprot id: Q5K6V7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SARAF family.
messages: Endoplasmic reticulum membrane
messages: Membrane

214684:CNH02270
gene id: 214684:CNH02270
uniprot id: Q5KCU4
names: Subcellular Location Annotation
messages: Membrane

214684:CNA06340
gene id: 214684:CNA06340
uniprot id: Q5KNI8
names: Similarity
messages: Belongs to the sulfiredoxin family.

214684:CNK00130
gene id: 214684:CNK00130
uniprot id: Q5K9Z8
names: Function
names: Similarity
messages: Belongs to the peroxiredoxin family. Prx6 subfamily.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively.

214684:CNE03920
gene id: 214684:CNE03920
uniprot id: Q5KGE3
names: Similarity
messages: Belongs to the universal ribosomal protein uL1 family.

214684:CNH02120
gene id: 214684:CNH02120
uniprot id: Q5KCS9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pex2/pex10/pex12 family.
messages: Component of the PEX2-PEX10-PEX12 retrotranslocation channel, composed of PEX2, PEX10 and PEX12.
messages: Membrane
messages: Peroxisome membrane

214684:CNB01910
gene id: 214684:CNB01910
uniprot id: Q5KMF3
names: Similarity
messages: Belongs to the universal ribosomal protein uL11 family.

214684:CNN02320
gene id: 214684:CNN02320
uniprot id: Q5K6T7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 48 family.
messages: Membrane

214684:CNH02730
gene id: 214684:CNH02730
uniprot id: Q5KCZ2
names: Similarity
messages: Belongs to the complex I 49 kDa subunit family.

214684:CNM00600
gene id: 214684:CNM00600
uniprot id: Q5K809
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

214684:CNJ01170
gene id: 214684:CNJ01170
uniprot id: Q5KAM5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RPAP2 family.
messages: Nucleus
messages: Putative RNA polymerase II subunit B1 C-terminal domain (CTD) phosphatase involved in RNA polymerase II transcription regulation.

214684:CNC03430
gene id: 214684:CNC03430
uniprot id: Q5KKD0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 22 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

214684:CNL04340
gene id: 214684:CNL04340
uniprot id: P0CO58
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Mitochondrion

214684:CNF02950
gene id: 214684:CNF02950
uniprot id: Q5KF53
names: Similarity
messages: Belongs to the PHF5 family.

214684:CNC05050
gene id: 214684:CNC05050
uniprot id: Q5KJX3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 22 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

214684:CNA07650
gene id: 214684:CNA07650
uniprot id: Q5KN57
names: Similarity
messages: Belongs to the NADH dehydrogenase family.

214684:CNE00260
gene id: 214684:CNE00260
uniprot id: Q5KHF4
names: Subcellular Location Annotation
messages: Membrane

214684:CNE02200
gene id: 214684:CNE02200
uniprot id: Q5KGV6
names: Similarity
messages: Belongs to the peptidase M24B family.

214684:CNG02360
gene id: 214684:CNG02360
uniprot id: Q5KDY6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the translin family.
messages: Nucleus

214684:CNK02220
gene id: 214684:CNK02220
uniprot id: Q5K9E5
names: Similarity
messages: Belongs to the GrpE family.

214684:CND02420
gene id: 214684:CND02420
uniprot id: Q5KIM6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCF family. EF3 subfamily.
messages: Cytoplasm

214684:CND02620
gene id: 214684:CND02620
uniprot id: Q5KIK6
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aconitase/IPM isomerase family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Mitochondrion

214684:CNA05150
gene id: 214684:CNA05150
uniprot id: P0CN66
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TIM50 family.
messages: Component of the TIM23 complex, at least composed of TIM23, TIM17 and TIM50. Interacts with preproteins in transit (By similarity).
messages: Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane. Required to direct preproteins in transit and direct them to the channel protein TIM23, and possibly facilitates transfer of the translocating proteins from the TOM complex to the TIM23 complex (By similarity).
messages: Mitochondrion inner membrane

214684:CNC04490
gene id: 214684:CNC04490
uniprot id: Q5KK26
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFB7 subunit family.
messages: Membrane
messages: Mitochondrion inner membrane
messages: Mitochondrion intermembrane space

214684:CNF01480
gene id: 214684:CNF01480
uniprot id: Q5KFK0
names: Similarity
messages: Belongs to the RutC family.

214684:CNF03760
gene id: 214684:CNF03760
uniprot id: Q5KEY5
names: Similarity
messages: Belongs to the peptidase S10 family.

214684:CNG02880
gene id: 214684:CNG02880
uniprot id: Q5KDT1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GOSR1 family.
messages: Component of several multiprotein Golgi SNARE complexes.
messages: Golgi apparatus membrane
messages: Involved in transport from the ER to the Golgi apparatus as well as in intra-Golgi transport. It belongs to a super-family of proteins called t-SNAREs or soluble NSF (N-ethylmaleimide-sensitive factor) attachment protein receptor.
messages: Membrane

214684:CNC05080
gene id: 214684:CNC05080
uniprot id: Q5KJX0
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. HMG-CoA synthase family.
messages: Catalyzes the condensation of acetyl-CoA with acetoacetyl-CoA to form HMG-CoA.

214684:CNK00750
gene id: 214684:CNK00750
uniprot id: P0CQ00
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PTPA-type PPIase family.
messages: Cytoplasm
messages: Nucleus
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. Acts as a regulatory subunit for PP2A-like phosphatases modulating their activity or substrate specificity, probably by inducing a conformational change in the catalytic subunit, a direct target of the PPIase. Can reactivate inactive phosphatase PP2A-phosphatase methylesterase complexes (PP2Ai) in presence of ATP and Mg(2+) by dissociating the inactive form from the complex (By similarity).

214684:CND01660
gene id: 214684:CND01660
uniprot id: Q5KIV1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1A family.
messages: Cytoplasm
messages: Nucleus
messages: The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits.

214684:CNB04180
gene id: 214684:CNB04180
uniprot id: Q5KLT0
names: Subcellular Location Annotation
messages: Membrane

214684:CNN00920
gene id: 214684:CNN00920
uniprot id: P0CN58
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the enhancer of polycomb family.
messages: Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histone H4 and H2A. The NuA4 complex is also involved in DNA repair. Involved in gene silencing by neighboring heterochromatin, blockage of the silencing spreading along the chromosome, and required for cell cycle progression through G2/M (By similarity).
messages: Component of the NuA4 histone acetyltransferase complex.
messages: Nucleus

214684:CNK01630
gene id: 214684:CNK01630
uniprot id: Q5K9K6
names: Similarity
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. NIM1 subfamily.

214684:CNH03160
gene id: 214684:CNH03160
uniprot id: Q5KD35
names: Similarity
messages: Belongs to the PhyH family.

214684:CNB01650
gene id: 214684:CNB01650
uniprot id: Q5KMH8
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

214684:CNA04500
gene id: 214684:CNA04500
uniprot id: Q5KP20
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SVP26 family.
messages: Membrane

214684:CNC03580
gene id: 214684:CNC03580
uniprot id: Q5KKB7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

214684:CNA03530
gene id: 214684:CNA03530
uniprot id: Q5KPA4
names: Subcellular Location Annotation
messages: Membrane

214684:CNG02090
gene id: 214684:CNG02090
uniprot id: P0CQ28
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GINS1/PSF1 family.
messages: Component of the GINS complex which is a heterotetramer of SLD5, PSF1, PSF2 and PSF3.
messages: Nucleus
messages: The GINS complex plays an essential role in the initiation of DNA replication.

214684:CNG02380
gene id: 214684:CNG02380
uniprot id: Q5KDY4
names: Similarity
messages: Belongs to the MCM family.

214684:CNB05200
gene id: 214684:CNB05200
uniprot id: Q5KLH9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

214684:CNL06020
gene id: 214684:CNL06020
uniprot id: Q5K8E2
names: Function
names: Similarity
messages: Belongs to the catalase family.
messages: Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide.

214684:CNC04750
gene id: 214684:CNC04750
uniprot id: P0CQ34
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP (By similarity).

214684:CND04680
gene id: 214684:CND04680
uniprot id: Q5KI03
names: Subcellular Location Annotation
messages: Nucleus

214684:CNH03850
gene id: 214684:CNH03850
uniprot id: Q5K904
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the actin-binding proteins ADF family. GMF subfamily.
messages: Cytoplasm
messages: Nucleus

214684:CNB02540
gene id: 214684:CNB02540
uniprot id: Q5KM89
names: Similarity
messages: Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.

214684:CNI01430
gene id: 214684:CNI01430
uniprot id: Q5KBT9
names: Similarity
messages: Belongs to the cyclin family.

214684:CND00950
gene id: 214684:CND00950
uniprot id: Q5KJ20
names: Similarity
messages: Belongs to the group II decarboxylase family.

214684:CND04770
gene id: 214684:CND04770
uniprot id: Q5KHZ4
names: Similarity
messages: Belongs to the importin alpha family.

214684:CNA06970
gene id: 214684:CNA06970
uniprot id: Q5KNC5
names: Subcellular Location Annotation
messages: Nucleus

214684:CNA02370
gene id: 214684:CNA02370
uniprot id: Q5KPL5
names: Similarity
messages: In the C-terminal section; belongs to the saccharopine dehydrogenase family.

214684:CND00030
gene id: 214684:CND00030
uniprot id: Q5KJA5
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

214684:CND01740
gene id: 214684:CND01740
uniprot id: Q5KIU3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alkaline ceramidase family.
messages: Membrane

214684:CNE01780
gene id: 214684:CNE01780
uniprot id: Q5KGZ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the steroid 5-alpha reductase family.
messages: Endoplasmic reticulum membrane
messages: Membrane

214684:CNB02560
gene id: 214684:CNB02560
uniprot id: P0CO12
names: Function
names: Subcellular Location Annotation
messages: Component of the cleavage factor IA (CFIA) complex, which is involved in the endonucleolytic cleavage during polyadenylation-dependent pre-mRNA 3'-end formation.
messages: Cytoplasm
messages: Nucleus

214684:CNF00070
gene id: 214684:CNF00070
uniprot id: Q5KFZ4
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 2 subfamily.

214684:CNC05070
gene id: 214684:CNC05070
uniprot id: Q5KJX1
names: Similarity
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.

214684:CNC00240
gene id: 214684:CNC00240
uniprot id: P0CP24
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NOP16 family.
messages: Component of the pre-66S ribosomal particle.
messages: Involved in the biogenesis of the 60S ribosomal subunit.
messages: nucleolus

214684:CNA01290
gene id: 214684:CNA01290
uniprot id: Q5KPW7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ESF1 family.
messages: nucleolus

214684:CNI03250
gene id: 214684:CNI03250
uniprot id: P0CP64
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PIGW family.
messages: Endoplasmic reticulum membrane
messages: Probable acetyltransferase, which acetylates the inositol ring of phosphatidylinositol during biosynthesis of GPI-anchor.

214684:CNI03410
gene id: 214684:CNI03410
uniprot id: P0CP10
names: Function
names: Similarity
messages: Belongs to the NARF family.
messages: Component of the cytosolic Fe/S protein assembly machinery. Required for maturation of extramitochondrial Fe/S proteins. May play a role in the transfer of pre-assembled Fe/S clusters to target apoproteins (By similarity).

214684:CNA07800
gene id: 214684:CNA07800
uniprot id: Q5KN42
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family.
messages: Membrane

214684:CNC03970
gene id: 214684:CNC03970
uniprot id: Q5KK78
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NadC/ModD family.
messages: Hexamer formed by 3 homodimers.
messages: Involved in the catabolism of quinolinic acid (QA).

214684:CNG02830
gene id: 214684:CNG02830
uniprot id: Q5KDT6
names: Similarity
messages: Belongs to the TSR2 family.

214684:CNB02070
gene id: 214684:CNB02070
uniprot id: Q5KMD6
names: Subcellular Location Annotation
messages: Nucleus

214684:CNH01280
gene id: 214684:CNH01280
uniprot id: Q5KCJ9
names: Similarity
messages: Belongs to the AP endonuclease 2 family.

214684:CNB04280
gene id: 214684:CNB04280
uniprot id: Q5KLS0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1A family.
messages: Cytoplasm
messages: Nucleus
messages: The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits.

214684:CNN00120
gene id: 214684:CNN00120
uniprot id: Q5K7E6
names: Similarity
messages: Belongs to the RRP12 family.

214684:CNH01810
gene id: 214684:CNH01810
uniprot id: Q5KCP7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIM41 family.
messages: Mitochondrion

214684:CNE04980
gene id: 214684:CNE04980
uniprot id: Q5KG38
names: Similarity
messages: Belongs to the universal ribosomal protein uL22 family.

214684:CNK02970
gene id: 214684:CNK02970
uniprot id: Q5K972
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CND1 (condensin subunit 1) family.
messages: Chromosome
messages: Nucleus
messages: Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases.

214684:CND01310
gene id: 214684:CND01310
uniprot id: Q5KIY4
names: Subcellular Location Annotation
messages: Membrane

214684:CNC06740
gene id: 214684:CNC06740
uniprot id: P0CM64
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CGI121/TPRKB family.
messages: Component of the EKC/KEOPS complex composed of at least BUD32, CGI121, GON7, KAE1 and PCC1; the whole complex dimerizes.
messages: Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. CGI121 acts as an allosteric effector that regulates the t(6)A activity of the complex. The EKC/KEOPS complex also promotes both telomere uncapping and telomere elongation. The complex is required for efficient recruitment of transcriptional coactivators. CGI121 is not required for tRNA modification (By similarity).
messages: Nucleus
messages: telomere

214684:CNF00940
gene id: 214684:CNF00940
uniprot id: Q5KFQ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat ARPC1 family.
messages: Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.
messages: actin patch

214684:CNB04350
gene id: 214684:CNB04350
uniprot id: Q5KLR3
names: Similarity
messages: Belongs to the WrbA family.

214684:CNG02870
gene id: 214684:CNG02870
uniprot id: Q5KDT2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TDE1 family.
messages: Membrane

214684:CNI01170
gene id: 214684:CNI01170
uniprot id: Q5KBW1
names: Similarity
messages: Belongs to the thiamine pyrophosphokinase family.

214684:CNA06820
gene id: 214684:CNA06820
uniprot id: Q5KNE0
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL31 family.

214684:CNA01550
gene id: 214684:CNA01550
uniprot id: Q5KPU0
names: Subcellular Location Annotation
messages: Peroxisome membrane

214684:CNB01360
gene id: 214684:CNB01360
uniprot id: Q5KMK7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic RPA49/POLR1E RNA polymerase subunit family.
messages: nucleolus

214684:CNG02080
gene id: 214684:CNG02080
uniprot id: Q5KE15
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterodimer of an alpha and a beta subunit.
messages: Mitochondrion
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

214684:CNM02600
gene id: 214684:CNM02600
uniprot id: Q5K7F7
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

214684:CNC01960
gene id: 214684:CNC01960
uniprot id: Q5KKT0
names: Similarity
messages: Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family.

214684:CNG03230
gene id: 214684:CNG03230
uniprot id: Q5KDP8
names: Subcellular Location Annotation
messages: Membrane

214684:CND03390
gene id: 214684:CND03390
uniprot id: Q5KID2
names: Function
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.
messages: Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.

214684:CND05150
gene id: 214684:CND05150
uniprot id: Q5KHV8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EMP24/GP25L family.
messages: Membrane

214684:CNG01800
gene id: 214684:CNG01800
uniprot id: Q5KE42
names: Similarity
messages: Belongs to the TACO1 family.

214684:CNN01420
gene id: 214684:CNN01420
uniprot id: Q5K720
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Adaptor protein complex 2 (AP-2) is a heterotetramer composed of two large adaptins (alpha-type subunit apl3 and beta-type subunit apl1), a medium chain (mu-type subunit apm4) and a small adaptin (sigma-type subunit aps2).
messages: Belongs to the adaptor complexes small subunit family.
messages: Cell membrane
messages: Component of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration.
messages: coated pit

214684:CNA05600
gene id: 214684:CNA05600
uniprot id: Q5KNR3
names: Function
names: Similarity
messages: Belongs to the catalase family.
messages: Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide.
messages: Serves to protect cells from the toxic effects of hydrogen peroxide.

214684:CND04530
gene id: 214684:CND04530
uniprot id: Q5KI18
names: Similarity
messages: Belongs to the XPC family.

214684:CNK00380
gene id: 214684:CNK00380
uniprot id: Q5K9X4
names: Subcellular Location Annotation
messages: Membrane

214684:CNM01770
gene id: 214684:CNM01770
uniprot id: Q5K7P0
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aconitase/IPM isomerase family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Mitochondrion

214684:CNM02230
gene id: 214684:CNM02230
uniprot id: P0CN20
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DPH1/DPH2 family. DPH2 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster facilitates the reduction of the catalytic iron-sulfur cluster in the DPH1 subunit.
messages: Component of the 2-(3-amino-3-carboxypropyl)histidine synthase complex composed of DPH1, DPH2, DPH3 and a NADH-dependent reductase, predominantly CBR1.
messages: Cytoplasm
messages: Required for the first step of diphthamide biosynthesis, a post-translational modification of histidine which occurs in elongation factor 2. DPH1 and DPH2 transfer a 3-amino-3-carboxypropyl (ACP) group from S-adenosyl-L-methionine (SAM) to a histidine residue, the reaction is assisted by a reduction system comprising DPH3 and a NADH-dependent reductase, predominantly CBR1 (By similarity). Facilitates the reduction of the catalytic iron-sulfur cluster found in the DPH1 subunit (By similarity).

214684:CNG00440
gene id: 214684:CNG00440
uniprot id: Q5KEI1
names: Subcellular Location Annotation
messages: Membrane

214684:CNN01700
gene id: 214684:CNN01700
uniprot id: Q5K6Z2
uniprot id: Q5K6Z3
names: Similarity
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.

214684:CNC06820
gene id: 214684:CNC06820
uniprot id: Q5KJE5
names: PTM
names: Similarity
messages: Belongs to the sulfatase family.
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

214684:CNI03280
gene id: 214684:CNI03280
uniprot id: Q5KB99
names: Function
names: Similarity
messages: Belongs to the type IB topoisomerase family.
messages: Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus removing DNA supercoils. Finally, in the religation step, the DNA 5'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

214684:CNE00790
gene id: 214684:CNE00790
uniprot id: P0CR80
names: Domain
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DENR family.
messages: Cytoplasm
messages: Interacts with the 40S ribosomal subunit.
messages: The SUI1 domain may be involved in RNA binding.

214684:CND04220
gene id: 214684:CND04220
uniprot id: Q5KI49
names: Subcellular Location Annotation
messages: Membrane

214684:CNA00210
gene id: 214684:CNA00210
uniprot id: Q5KQ74
names: Subcellular Location Annotation
messages: Membrane

214684:CNB00570
gene id: 214684:CNB00570
uniprot id: Q5KMT3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H3 family.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

214684:CNA00360
gene id: 214684:CNA00360
uniprot id: Q5KQ59
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PDK/BCKDK protein kinase family.
messages: Mitochondrion matrix

214684:CNM02420
gene id: 214684:CNM02420
uniprot id: Q5K7H5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the multicopper oxidase family.
messages: Secreted

214684:CNK02540
gene id: 214684:CNK02540
uniprot id: Q5K9B3
names: Similarity
messages: Belongs to the SEC6 family.

214684:CNA00800
gene id: 214684:CNA00800
uniprot id: Q5KQ16
names: Similarity
messages: Belongs to the putative lipase ROG1 family.

214684:CNF04070
gene id: 214684:CNF04070
uniprot id: Q5KEV9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SDE2 family.
messages: Cytoplasm
messages: Nucleus

214684:CNL04500
gene id: 214684:CNL04500
uniprot id: Q5K8U1
names: Subcellular Location Annotation
messages: Nucleus

214684:CNJ01690
gene id: 214684:CNJ01690
uniprot id: P0CM86
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COX19 family.
messages: Cytoplasm
messages: Mitochondrion intermembrane space
messages: Required for the assembly of mitochondrial cytochrome c oxidase.

214684:CNA00830
gene id: 214684:CNA00830
uniprot id: Q5KQ14
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial pyruvate carrier (MPC) (TC 2.A.105) family.
messages: Mediates the uptake of pyruvate into mitochondria.
messages: Membrane
messages: Mitochondrion inner membrane

214684:CNB03740
gene id: 214684:CNB03740
uniprot id: Q5KLX2
names: Similarity
messages: Belongs to the CCDC25 family.

214684:CND02590
gene id: 214684:CND02590
uniprot id: P0CS42
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the WD repeat LIS1/nudF family.
messages: Dimerization mediated by the LisH domain may be required to activate dynein.
messages: Positively regulates the activity of the minus-end directed microtubule motor protein dynein. Plays a central role in positioning the mitotic spindle at the bud neck during cell division. Targets cytoplasmic dynein to microtubule plus ends, thereby promoting dynein-mediated microtubule sliding along the bud cortex and consequently the movement of the mitotic spindle to the bud neck.
messages: Self-associates. Interacts with NDL1 and dynein.
messages: cytoskeleton
messages: spindle pole

214684:CNF00630
gene id: 214684:CNF00630
uniprot id: Q5KFT4
names: Cofactor
names: Subcellular Location Annotation
messages: Binds 1 heme c group covalently per subunit.
messages: Membrane
messages: Mitochondrion inner membrane

214684:CNH02710
gene id: 214684:CNH02710
uniprot id: P0CM88
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. CPSF2/YSH1 subfamily.
messages: Component of the cleavage factor I (CF I) involved in pre-mRNA 3'-end processing.
messages: Nucleus

214684:CNE00940
gene id: 214684:CNE00940
uniprot id: Q5KH82
names: Subcellular Location Annotation
messages: Membrane

214684:CND02040
gene id: 214684:CND02040
uniprot id: Q5KIR4
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

214684:CNG03790
gene id: 214684:CNG03790
uniprot id: P0CP22
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acts as catalytic component of the CCR4-NOT core complex, which in the nucleus seems to be a general transcription factor, and in the cytoplasm the major mRNA deadenylase involved in mRNA turnover (By similarity). Ccr4 has 3'-5' RNase activity with a strong preference for polyadenylated substrates and also low exonuclease activity towards single-stranded DNA (By similarity).
messages: Belongs to the CCR4/nocturin family.
messages: Cytoplasm
messages: Nucleus

214684:CNA03410
gene id: 214684:CNA03410
uniprot id: Q5KPB5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ORC3 family.
messages: Nucleus

214684:CNI04210
gene id: 214684:CNI04210
uniprot id: Q5KB07
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine-cytosine permease (2.A.39) family.
messages: Membrane

214684:CNG01720
gene id: 214684:CNG01720
uniprot id: Q5KE51
names: Similarity
messages: Belongs to the glycosyl hydrolase 18 family.

214684:CNG02800
gene id: 214684:CNG02800
uniprot id: P0CS36
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the WD repeat RBAP46/RBAP48/MSI1 family.
messages: Component of the HAT-B complex composed of at least HAT1 and HAT2. The HAT-B complex binds to histone H4 tail.
messages: Cytoplasm
messages: Nucleus
messages: Regulatory subunit of the histone acetylase B (HAT-B) complex. The complex acetylates 'Lys-12' of histone H4 which is required for telomeric silencing.

214684:CNB03970
gene id: 214684:CNB03970
uniprot id: Q5KLV1
names: Subcellular Location Annotation
messages: Membrane

214684:CNC06440
gene id: 214684:CNC06440
uniprot id: Q5KJI4
names: Similarity
messages: Belongs to the myo-inositol 1-phosphate synthase family.

214684:CNF00790
gene id: 214684:CNF00790
uniprot id: Q5KFR9
names: Subunit
messages: Consists of at least two heavy chains and a number of intermediate and light chains.

214684:CND04400
gene id: 214684:CND04400
uniprot id: Q5KI31
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL17 family.

214684:CNM01830
gene id: 214684:CNM01830
uniprot id: Q5K7N4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ORC4 family.
messages: Nucleus

214684:CNC01880
gene id: 214684:CNC01880
uniprot id: Q5KKT8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YIF1 family.
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Has a role in transport between endoplasmic reticulum and Golgi.
messages: Membrane

214684:CNC02690
gene id: 214684:CNC02690
uniprot id: Q5KKK6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane
messages: Mitochondrion inner membrane

214684:CNB01130
gene id: 214684:CNB01130
uniprot id: Q5KMM9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic GTase family.
messages: Heterodimer.
messages: Nucleus
messages: Second step of mRNA capping. Transfer of the GMP moiety of GTP to the 5'-end of RNA via an enzyme-GMP covalent reaction intermediate.

214684:CNG03580
gene id: 214684:CNG03580
uniprot id: Q5KDL0
names: Subcellular Location Annotation
messages: Membrane

214684:CNE02910
gene id: 214684:CNE02910
uniprot id: Q5KGN5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

214684:CNA04330
gene id: 214684:CNA04330
uniprot id: Q5KP35
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

214684:CNE03440
gene id: 214684:CNE03440
uniprot id: Q5KGJ0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ORC1 family.
messages: Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication.
messages: Nucleus
messages: ORC is composed of six subunits.

214684:CNA00760
gene id: 214684:CNA00760
uniprot id: Q5KQ20
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. Trm1 family.

214684:CND05630
gene id: 214684:CND05630
uniprot id: Q5KHQ9
names: Similarity
messages: Belongs to the pantothenate synthetase family.

214684:CNE04580
gene id: 214684:CNE04580
uniprot id: Q5KG77
names: Similarity
messages: Belongs to the glycosyl hydrolase 63 family.

214684:CNG03080
gene id: 214684:CNG03080
uniprot id: Q5KDR2
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

214684:CNN00150
gene id: 214684:CNN00150
uniprot id: Q5K7E3
names: Similarity
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.

214684:CNB04660
gene id: 214684:CNB04660
uniprot id: Q5KLN4
names: Similarity
messages: Belongs to the ADIP family.

214684:CNA02650
gene id: 214684:CNA02650
uniprot id: Q5KPI8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Cotranslationally removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val).

214684:CNI03470
gene id: 214684:CNI03470
uniprot id: Q5KB79
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

214684:CNE03640
gene id: 214684:CNE03640
uniprot id: Q5KGH0
names: Similarity
messages: Belongs to the TRAPP small subunits family. BET3 subfamily.

214684:CNA05680
gene id: 214684:CNA05680
uniprot id: Q5KNQ6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the profilin family.
messages: Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations.
messages: Occurs in many kinds of cells as a complex with monomeric actin in a 1:1 ratio.

214684:CNE02570
gene id: 214684:CNE02570
uniprot id: Q5KGS0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

214684:CNH01530
gene id: 214684:CNH01530
uniprot id: Q5KCL8
names: Similarity
messages: Belongs to the IlvD/Edd family.

214684:CNB02300
gene id: 214684:CNB02300
uniprot id: Q5KMB2
names: Subcellular Location Annotation
messages: Membrane

214684:CNJ00640
gene id: 214684:CNJ00640
uniprot id: P0CR48
names: Similarity
messages: Belongs to the CSN12 family.

214684:CND04490
gene id: 214684:CND04490
uniprot id: Q5KI22
names: Subcellular Location Annotation
messages: Chromosome

214684:CNC00210
gene id: 214684:CNC00210
uniprot id: Q5KLA2
names: Similarity
messages: Belongs to the HMG-CoA lyase family.

214684:CNJ02990
gene id: 214684:CNJ02990
uniprot id: Q5KA56
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sideroflexin family.
messages: Membrane

214684:CNB03430
gene id: 214684:CNB03430
uniprot id: P0CR30
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the small GTPase superfamily. SAR1 family.
messages: COPII is composed of at least 5 proteins: the SEC23/24 complex, the SEC13/31 complex and SAR1.
messages: COPII-coated vesicle membrane
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Small GTPase component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules. SAR1 controls the coat assembly in a stepwise manner. Activated SAR1-GTP binds to membranes first and recruits the SEC23/24 complex. These SEC23/24-SAR1 prebudding intermediates are then collected by the SEC13/31 complex as subunits polymerize to form coated transport vesicles. Conversion to SAR1-GDP triggers coat release and recycles COPII subunits (By similarity).

214684:CNN01950
gene id: 214684:CNN01950
uniprot id: Q5K6W5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DEF1 family.
messages: Cytoplasm
messages: Nucleus
messages: telomere

214684:CNG00110
gene id: 214684:CNG00110
uniprot id: Q5KEL4
names: Subcellular Location Annotation
messages: Membrane

214684:CNB05680
gene id: 214684:CNB05680
uniprot id: Q5KLD3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adaptor complexes small subunit family.
messages: COPI-coated vesicle membrane
messages: Cytoplasm
messages: Golgi apparatus membrane
messages: Oligomeric complex that consists of at least the alpha, beta, beta', gamma, delta, epsilon and zeta subunits.
messages: The zeta subunit may be involved in regulating the coat assembly and, hence, the rate of biosynthetic protein transport due to its association-dissociation properties with the coatomer complex.

214684:CNF02800
gene id: 214684:CNF02800
uniprot id: Q5KF69
names: Similarity
messages: Belongs to the protein kinase superfamily.

214684:CNN01180
gene id: 214684:CNN01180
uniprot id: Q5K742
names: Subcellular Location Annotation
messages: Nucleus

214684:CND06150
gene id: 214684:CND06150
uniprot id: Q5KHK5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 39 family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Transfers mannose from Dol-P-mannose to Ser or Thr residues on proteins.

214684:CND00550
gene id: 214684:CND00550
uniprot id: Q5KJ60
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SKN1/KRE6 family.
messages: Membrane

214684:CNK00940
gene id: 214684:CNK00940
uniprot id: Q5K9S4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. UbiG/COQ3 family.
messages: Component of a multi-subunit COQ enzyme complex, composed of at least COQ3, COQ4, COQ5, COQ6, COQ7 and COQ9.
messages: Mitochondrion inner membrane
messages: O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway.

214684:CNC02070
gene id: 214684:CNC02070
uniprot id: Q5KKR7
names: Similarity
messages: Belongs to the XPO2/CSE1 family.

214684:CNI03170
gene id: 214684:CNI03170
uniprot id: Q5KBB0
names: Similarity
messages: Belongs to the universal ribosomal protein uL15 family.

214684:CNJ01780
gene id: 214684:CNJ01780
uniprot id: Q5KAG5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OS-9 family.
messages: Endoplasmic reticulum membrane

214684:CNE00300
gene id: 214684:CNE00300
uniprot id: Q5KHF0
names: Similarity
messages: Belongs to the IST1 family.

214684:CNC03380
gene id: 214684:CNC03380
uniprot id: Q5KKD5
names: Similarity
messages: Belongs to the dermatan-sulfate isomerase family.

214684:CNK01690
gene id: 214684:CNK01690
uniprot id: Q5K9K0
names: Similarity
messages: Belongs to the histidine acid phosphatase family.

214684:CNA05470
gene id: 214684:CNA05470
uniprot id: Q5KNS5
names: Similarity
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.

214684:CNE01760
gene id: 214684:CNE01760
uniprot id: Q5KH00
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TUBGCP family.
messages: microtubule organizing center

214684:CNA06750
gene id: 214684:CNA06750
uniprot id: Q5KNE7
names: Similarity
messages: Belongs to the glycosyl hydrolase 38 family.

214684:CNN01860
gene id: 214684:CNN01860
uniprot id: Q5K6X5
names: Similarity
messages: Belongs to the CDC50/LEM3 family.

214684:CND03910
gene id: 214684:CND03910
uniprot id: P0CO36
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associated with the spliceosome.
messages: Belongs to the ISY1 family.
messages: Cytoplasm
messages: Involved in pre-mRNA splicing.
messages: Nucleus

214684:CNB04640
gene id: 214684:CNB04640
uniprot id: P0CS34
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the WD repeat BOP1/ERB1 family.
messages: Component of the NOP7 complex, composed of ERB1, NOP7 and YTM1. The complex is held together by ERB1, which interacts with NOP7 via its N-terminal domain and with YTM1 via a high-affinity interaction between the seven-bladed beta-propeller domains of the 2 proteins. The NOP7 complex associates with the 66S pre-ribosome.
messages: Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome.
messages: nucleolus
messages: nucleoplasm

214684:CNF01340
gene id: 214684:CNF01340
uniprot id: Q5KFL5
names: Function
names: Similarity
messages: Belongs to the cytochrome c oxidase subunit 6B family.
messages: Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.

214684:CNK01620
gene id: 214684:CNK01620
uniprot id: Q5K9K8
names: Similarity
messages: Belongs to the DeSI family.

214684:CNK01400
gene id: 214684:CNK01400
uniprot id: Q5K9N0
names: Similarity
messages: Belongs to the glutaminase PdxT/SNO family.

214684:CNG00380
gene id: 214684:CNG00380
uniprot id: Q5KEI8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIIA subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The plasma membrane ATPase of plants and fungi is a hydrogen ion pump. The proton gradient it generates drives the active transport of nutrients by H(+)-symport. The resulting external acidification and/or internal alkinization may mediate growth responses.

214684:CNC05910
gene id: 214684:CNC05910
uniprot id: Q5KJN4
names: Subcellular Location Annotation
messages: nucleolus

214684:CNA07740
gene id: 214684:CNA07740
uniprot id: Q5KN48
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

214684:CNL04110
gene id: 214684:CNL04110
uniprot id: Q5K8X8
uniprot id: Q5K8X9
names: Similarity
messages: Belongs to the CAP family.

214684:CNC00910
gene id: 214684:CNC00910
uniprot id: Q5KL33
uniprot id: Q5KL34
names: Function
names: Similarity
messages: Belongs to the endosulfine family.
messages: Plays an essential role in initiation of the G0 program by preventing the degradation of specific nutrient-regulated mRNAs via the 5'-3' mRNA decay pathway.

214684:CNB01300
gene id: 214684:CNB01300
uniprot id: Q5KML3
names: Similarity
messages: Belongs to the STXBP/unc-18/SEC1 family.

214684:CNK01080
gene id: 214684:CNK01080
uniprot id: Q5K9R0
names: Similarity
messages: Belongs to the p23/wos2 family.

214684:CNF01470
gene id: 214684:CNF01470
uniprot id: Q5KFK1
names: Subcellular Location Annotation
messages: Membrane

214684:CNA04240
gene id: 214684:CNA04240
uniprot id: Q5KP44
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Cytoplasm
messages: Homotetramer.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

214684:CNA01920
gene id: 214684:CNA01920
uniprot id: Q5KPQ4
names: Similarity
messages: Belongs to the CACTIN family.

214684:CNC00120
gene id: 214684:CNC00120
uniprot id: Q5KLB0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PGAP3 family.
messages: Endoplasmic reticulum membrane
messages: Involved in the lipid remodeling steps of GPI-anchor maturation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

214684:CNG00900
gene id: 214684:CNG00900
uniprot id: Q5KED3
names: Subcellular Location Annotation
messages: Membrane

214684:CNE04530
gene id: 214684:CNE04530
uniprot id: Q5KG81
names: Subcellular Location Annotation
messages: Membrane

214684:CNB02570
gene id: 214684:CNB02570
uniprot id: P0CS78
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. SPB1 subfamily.
messages: Component of the nucleolar and nucleoplasmic pre-60S ribosomal particle.
messages: Required for proper assembly of pre-ribosomal particles during the biogenesis of the 60S ribosomal subunit.
messages: nucleolus

214684:CNI00920
gene id: 214684:CNI00920
uniprot id: Q5KBY8
names: Similarity
messages: Belongs to the Luc7 family.

214684:CNH00560
gene id: 214684:CNH00560
uniprot id: Q5KCC8
names: Similarity
messages: Belongs to the group II decarboxylase family.

214684:CNA03480
gene id: 214684:CNA03480
uniprot id: Q5KPA9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SVF1 family.
messages: Cytoplasm

214684:CNA00900
gene id: 214684:CNA00900
uniprot id: Q5KQ07
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as component of the MCM2-7 complex (MCM complex) which is the replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity.
messages: Belongs to the MCM family.
messages: Component of the MCM2-7 complex.
messages: Nucleus

214684:CNJ00390
gene id: 214684:CNJ00390
uniprot id: Q5KAV0
names: Function
names: Similarity
messages: Belongs to the PanB family.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.

214684:CNI01730
gene id: 214684:CNI01730
uniprot id: Q5KBQ8
names: Similarity
messages: Belongs to the KRI1 family.

214684:CNB03210
gene id: 214684:CNB03210
uniprot id: Q5KM27
names: Similarity
messages: Belongs to the glycosyltransferase 15 family.

214684:CNA07010
gene id: 214684:CNA07010
uniprot id: P0CQ48
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial ribosomal protein bL27 family.
messages: Mitochondrion

214684:CNA01950
gene id: 214684:CNA01950
uniprot id: Q5KPQ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I NDUFB11 subunit family.
messages: Membrane

214684:CNB00800
gene id: 214684:CNB00800
uniprot id: Q5KMR1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CybS family.
messages: Membrane
messages: Mitochondrion inner membrane

214684:CNH02980
gene id: 214684:CNH02980
uniprot id: P0CR74
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SSRP1 family.
messages: Chromosome
messages: Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment of the nucleosome following the passage of RNA polymerase II (By similarity).
messages: Forms a stable heterodimer with SPT16. The SPT16-POB3 dimer weakly associates with multiple molecules of NHP6 to form the FACT complex (By similarity).
messages: In contrast to the orthologous protein in animals and plants, this protein does not contain a HMG box DNA-binding domain. This function may instead be provided by the HMG box of the associated NHP6 protein in the FACT complex of fungi.
messages: Nucleus

214684:CNK01950
gene id: 214684:CNK01950
uniprot id: Q5K9H2
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.

214684:CNH01170
gene id: 214684:CNH01170
uniprot id: Q5KCI8
names: Similarity
messages: Belongs to the eIF-1A family.

214684:CNC01730
gene id: 214684:CNC01730
uniprot id: Q5KKV3
names: Similarity
messages: Belongs to the eIF-2B alpha/beta/delta subunits family.

214684:CNC01280
gene id: 214684:CNC01280
uniprot id: Q5KKZ9
names: Subcellular Location Annotation
messages: Nucleus

214684:CNJ01590
gene id: 214684:CNJ01590
uniprot id: P0CQ94
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: ATP-binding RNA helicase involved in the biogenesis of 60S ribosomal subunits and is required for the normal formation of 25S and 5.8S rRNAs.
messages: Belongs to the DEAD box helicase family. DDX31/DBP7 subfamily.
messages: The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.
messages: nucleolus

214684:CNC01140
gene id: 214684:CNC01140
uniprot id: P0CO60
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AB hydrolase superfamily. Lipase family.
messages: Binds to both phosphatidylinositol (PI) and phosphatidylinositol 3,5-bisphosphate (PIP2).
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Lipase which is essential for lysis of subvacuolar cytoplasm to vacuole targeted bodies and intravacuolar autophagic bodies. Involved in the lysis of intravacuolar multivesicular body (MVB) vesicles. The intravacuolar membrane disintegration by ATG15 is critical to life span extension (By similarity).
messages: Prevacuolar compartment membrane
messages: multivesicular body membrane

214684:CNA02250
gene id: 214684:CNA02250
uniprot id: Q5KPM5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

214684:CNC03420
gene id: 214684:CNC03420
uniprot id: Q5KKD1
names: Similarity
messages: Belongs to the EF-1-beta/EF-1-delta family.

214684:CNI02800
gene id: 214684:CNI02800
uniprot id: Q5KBE7
names: Subcellular Location Annotation
messages: Membrane

214684:CNG00100
gene id: 214684:CNG00100
uniprot id: Q5KEL5
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

214684:CND01270
gene id: 214684:CND01270
uniprot id: Q5KIY8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM19 family.
messages: Membrane

214684:CNC02000
gene id: 214684:CNC02000
uniprot id: Q5KKS5
names: Function
names: Similarity
messages: Belongs to the ubiquitin-activating E1 family. UBA3 subfamily.
messages: Catalytic subunit of the dimeric E1 enzyme, which activates NEDD8.

214684:CNN01780
gene id: 214684:CNN01780
uniprot id: Q5K6Y3
names: Similarity
messages: Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family.

214684:CNA02150
gene id: 214684:CNA02150
uniprot id: Q5KPN3
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

214684:CNG04600
gene id: 214684:CNG04600
uniprot id: Q5KDB8
names: Similarity
messages: Belongs to the MOG1 family.

214684:CNH02390
gene id: 214684:CNH02390
uniprot id: Q5KCV8
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Has a role in nuclear-cytoplasmic transport of proteins and mRNAs.
messages: Nucleus

214684:CNE02710
gene id: 214684:CNE02710
uniprot id: Q5KGQ6
names: Similarity
messages: Belongs to the putative lipase ROG1 family.

214684:CNC05520
gene id: 214684:CNC05520
uniprot id: Q5KJS6
names: Subcellular Location Annotation
messages: Membrane

214684:CNI00410
gene id: 214684:CNI00410
uniprot id: Q5KC34
names: Activity Regulation
names: Similarity
messages: Activated by threonine and tyrosine phosphorylation.
messages: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.

214684:CNA04090
gene id: 214684:CNA04090
uniprot id: Q5KP59
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity.
messages: Belongs to the SPC24 family.
messages: Component of the NDC80 complex.
messages: Nucleus
messages: kinetochore

214684:CNF04680
gene id: 214684:CNF04680
uniprot id: Q5KEQ1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the fungal TPase family.
messages: First step of mRNA capping. Converts the 5'-triphosphate end of a nascent mRNA chain into a diphosphate end.
messages: Heterodimer. The mRNA-capping enzyme is composed of two separate chains alpha and beta, respectively a mRNA guanylyltransferase and an mRNA 5'-triphosphate monophosphatase.
messages: Nucleus

214684:CNF02430
gene id: 214684:CNF02430
uniprot id: P0CL94
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AB hydrolase superfamily. AB hydrolase 2 family.
messages: Cytoplasm
messages: Hydrolyzes fatty acids from S-acylated cysteine residues in proteins with a strong preference for palmitoylated G-alpha proteins over other acyl substrates. Mediates the deacylation of G-alpha proteins such as GPA1 in vivo, but has weak or no activity toward palmitoylated Ras proteins. Has weak lysophospholipase activity in vitro; however such activity may not exist in vivo.
messages: Nucleus

214684:CNA00890
gene id: 214684:CNA00890
uniprot id: Q5KQ08
names: Similarity
messages: Belongs to the palmitoyl-protein thioesterase family.

214684:CNE03110
gene id: 214684:CNE03110
uniprot id: Q5KGM3
names: Similarity
messages: Belongs to the protein prenyltransferase subunit alpha family.

214684:CNA01180
gene id: 214684:CNA01180
uniprot id: Q5KPX9
uniprot id: Q5KPY0
names: Similarity
messages: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. Aurora subfamily.

214684:CNH00550
gene id: 214684:CNH00550
uniprot id: Q5KCC7
names: Similarity
messages: Belongs to the FPG family.

214684:CNK01520
gene id: 214684:CNK01520
uniprot id: P0CQ10
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C54 family.
messages: Cysteine protease that plays a key role in cytoplasm to vacuole transport (Cvt) and autophagy by mediating both proteolytic activation and delipidation of ATG8. Required for selective autophagic degradation of the nucleus (nucleophagy) as well as for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production. The protease activity is required for proteolytic activation of ATG8: cleaves the C-terminal amino acid of ATG8 to reveal a C-terminal glycine. ATG8 ubiquitin-like activity requires the exposure of the glycine at the C-terminus for its conjugation to phosphatidylethanolamine (PE) and its insertion to membranes, which is necessary for autophagy. The ATG8-PE conjugate mediates tethering between adjacent membranes and stimulates membrane hemifusion, leading to expansion of the autophagosomal membrane during autophagy. In addition to the protease activity, also catalyzes deconjugation of PE-conjugated forms of ATG8 during macroautophagy: ATG8 delipidation is required to release the protein from membranes, which facilitates multiple events during macroautophagy, and especially for efficient autophagosome biogenesis, the assembly of ATG9-containing tubulovesicular clusters into phagophores/autophagosomes, and for the disassembly of PAS-associated ATG components. ATG8 delipidation by ATG4 also recycles ATG8-PE generated on inappropriate membranes to maintain a reservoir of unlipidated ATG8 that is required for autophagosome formation at the PAS.
messages: Cytoplasm
messages: Nucleus
messages: Preautophagosomal structure

214684:CNA06200
gene id: 214684:CNA06200
uniprot id: Q5KNK2
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS4 family.

214684:CNH00270
gene id: 214684:CNH00270
uniprot id: Q5KC98
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts in a DNA repair pathway for removal of UV-induced DNA damage that is distinct from classical nucleotide excision repair and in repair of ionizing radiation damage. Functions in homologous recombination repair of DNA double strand breaks and in recovery of stalled replication forks.
messages: Belongs to the NSE1 family.
messages: Component of the Smc5-Smc6 complex.
messages: Nucleus

214684:CNC02800
gene id: 214684:CNC02800
uniprot id: Q5KKJ4
names: Cofactor
names: Function
names: Similarity
messages: Adds a GMP to the 5'-end of tRNA(His) after transcription and RNase P cleavage.
messages: Belongs to the tRNA(His) guanylyltransferase family.
messages: Binds 2 magnesium ions per subunit.

214684:CNC02540
gene id: 214684:CNC02540
uniprot id: Q5KKM2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

214684:CNH01270
gene id: 214684:CNH01270
uniprot id: Q5KCJ8
names: Similarity
messages: Belongs to the WD repeat G protein beta family. Ribosomal protein RACK1 subfamily.

214684:CNM02370
gene id: 214684:CNM02370
uniprot id: Q5K7I0
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

214684:CNC04420
gene id: 214684:CNC04420
uniprot id: Q5KK33
names: Similarity
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.

214684:CND00420
gene id: 214684:CND00420
uniprot id: Q5KJ71
names: Subcellular Location Annotation
messages: Peroxisome membrane

214684:CNL06050
gene id: 214684:CNL06050
uniprot id: Q5K8D9
names: Similarity
messages: Belongs to the frataxin family.

214684:CNB00550
gene id: 214684:CNB00550
uniprot id: P0CN98
names: Caution
names: Domain
names: Function
names: Miscellaneous
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetylated by ESA1 to form H2AK4ac and H2AK7ac.
messages: Belongs to the histone H2A family.
messages: Chromosome
messages: Core component of nucleosome which plays a central role in DNA double strand break (DSB) repair. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
messages: In contrast to vertebrates and insects, its C-terminus is not monoubiquitinated.
messages: Nucleus
messages: Phosphorylated to form H2AS128ph (gamma-H2A) in response to DNA double-strand breaks (DSBs) generated by exogenous genotoxic agents and by stalled replication forks. Phosphorylation is dependent on the DNA damage checkpoint kinases MEC1/ATR and TEL1/ATM, spreads on either side of a detected DSB site and may mark the surrounding chromatin for recruitment of proteins required for DNA damage signaling and repair. Gamma-H2A is removed from the DNA prior to the strand invasion-primer extension step of the repair process and subsequently dephosphorylated. Dephosphorylation is necessary for efficient recovery from the DNA damage checkpoint (By similarity).
messages: The [ST]-Q motif constitutes a recognition sequence for kinases from the PI3/PI4-kinase family.
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.
messages: To ensure consistency between histone entries, we follow the 'Brno' nomenclature for histone modifications, with positions referring to those used in the literature for the 'closest' model organism. Due to slight variations in histone sequences between organisms and to the presence of initiator methionine in UniProtKB/Swiss-Prot sequences, the actual positions of modified amino acids in the sequence generally differ. In this entry the following conventions are used: H2AK4ac = acetylated Lys-6; H2AK7ac = acetylated Lys-8; H2AS128ph = phosphorylated Ser-128.

214684:CNA02540
gene id: 214684:CNA02540
uniprot id: Q5KPJ8
names: Similarity
messages: Belongs to the nuclease type I family.

214684:CND05230
gene id: 214684:CND05230
uniprot id: Q5KHU9
names: Similarity
messages: Belongs to the lipin family.

214684:CNG03000
gene id: 214684:CNG03000
uniprot id: Q5KDS0
names: Similarity
messages: Belongs to the PhyH family.

214684:CNB02100
gene id: 214684:CNB02100
uniprot id: Q5KMD2
uniprot id: Q5KMD3
names: Subcellular Location Annotation
messages: Membrane

214684:CNA06870
gene id: 214684:CNA06870
uniprot id: Q5KND5
names: Similarity
messages: Belongs to the glutamine synthetase family.

214684:CND05030
gene id: 214684:CND05030
uniprot id: Q5KHW9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDC37 family.
messages: Cytoplasm

214684:CNM01030
gene id: 214684:CNM01030
uniprot id: Q5K7W7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

214684:CNG03270
gene id: 214684:CNG03270
uniprot id: Q5KDP4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA 3'-terminal cyclase family. Type 2 subfamily.
messages: nucleolus

214684:CNB02870
gene id: 214684:CNB02870
uniprot id: Q5KM56
names: Similarity
messages: Belongs to the universal ribosomal protein uS14 family.

214684:CND02700
gene id: 214684:CND02700
uniprot id: Q5KIJ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the borealin family.
messages: centromere

214684:CNE05180
gene id: 214684:CNE05180
uniprot id: Q5KG18
names: Subcellular Location Annotation
messages: Membrane

214684:CNC05540
gene id: 214684:CNC05540
uniprot id: Q5KJS3
names: Similarity
messages: Belongs to the histidine acid phosphatase family.

214684:CND00990
gene id: 214684:CND00990
uniprot id: Q5KJ16
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

214684:CNK00580
gene id: 214684:CNK00580
uniprot id: P0CM02
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aconitase/IPM isomerase family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the reversible hydration of cis-homoaconitate to (2R,3S)-homoisocitrate, a step in the alpha-aminoadipate pathway for lysine biosynthesis.
messages: Mitochondrion

214684:CNF01740
gene id: 214684:CNF01740
uniprot id: Q5KFH4
names: Subcellular Location Annotation
messages: Nucleus

214684:CNB05580
gene id: 214684:CNB05580
uniprot id: Q5KLE3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MPP10 family.
messages: Involved in nucleolar processing of pre-18S ribosomal RNA.
messages: nucleolus

214684:CNL04750
gene id: 214684:CNL04750
uniprot id: Q5K8R6
names: Disruption Phenotype
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Attenuation of cryptococcal growth in a mouse model of infection due to defects in capsule polysaccharide content. The general morphology of the capsule is normal but two main capsule polysaccharides, glucuronoxylomannan (GXM) and galactoxylomannan (GalXM), lack beta-1,2-xylose residues.
messages: Belongs to the glycosyltransferase 90 family.
messages: Beta-1,2-xylosyltransferase that plays a key role in capsule polysaccharide synthesis by transferring xylose to alpha-1,3-dimannoside in a beta-1,2-linkage. Also mediates glycosylation of glycosphingolipids; constitutes the unique xylosyltransferase responsible for adding xylose to glycosphingolipids.
messages: Membrane

214684:CNA05220
gene id: 214684:CNA05220
uniprot id: Q5KNV1
names: Subcellular Location Annotation
messages: Membrane

214684:CNF01220
gene id: 214684:CNF01220
uniprot id: Q5KFM8
names: Subcellular Location Annotation
messages: Membrane

214684:CNA07620
gene id: 214684:CNA07620
uniprot id: P0CQ70
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent RNA helicase which is a subunit of the eIF4F complex involved in cap recognition and is required for mRNA binding to ribosome. In the current model of translation initiation, eIF4A unwinds RNA secondary structures in the 5'-UTR of mRNAs which is necessary to allow efficient binding of the small ribosomal subunit, and subsequent scanning for the initiator codon (By similarity).
messages: Belongs to the DEAD box helicase family. eIF4A subfamily.
messages: Component of the eIF4F complex, which composition varies with external and internal environmental conditions. It is composed of at least eIF4A, eIF4E and eIF4G (By similarity).
messages: Cytoplasm
messages: The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.

214684:CNN00870
gene id: 214684:CNN00870
uniprot id: Q5K772
names: Similarity
messages: Belongs to the proteasome subunit S9 family.

214684:CND00940
gene id: 214684:CND00940
uniprot id: Q5KJ21
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family.
messages: Binds 1 Mg(2+) ion per subunit. Can also utilize other divalent metal cations, such as Ca(2+), Mn(2+) and Co(2+).
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
messages: Homodimer.

214684:CNE00210
gene id: 214684:CNE00210
uniprot id: Q5KHF9
names: Similarity
messages: Belongs to the PPase family.

214684:CNC05320
gene id: 214684:CNC05320
uniprot id: Q5KJU6
names: Similarity
messages: Belongs to the universal ribosomal protein uL14 family.

214684:CNC00160
gene id: 214684:CNC00160
uniprot id: Q5KLA7
names: Similarity
messages: Belongs to the enolase family.

214684:CNA03500
gene id: 214684:CNA03500
uniprot id: P0CM60
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the beta-catenin family.
messages: Functions in both vacuole inheritance and protein targeting from the cytoplasm to vacuole.
messages: Vacuole membrane

214684:CNC05650
gene id: 214684:CNC05650
uniprot id: P0CO38
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IWS1 family.
messages: Nucleus
messages: Transcription factor involved in RNA polymerase II transcription regulation. May function in both SPT15/TBP post-recruitment and recruitment steps of transcription (By similarity).

214684:CNK02580
gene id: 214684:CNK02580
uniprot id: Q5K9A9
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.

214684:CNK00540
gene id: 214684:CNK00540
uniprot id: Q5K9W4
names: Subcellular Location Annotation
messages: Membrane

214684:CNE01840
gene id: 214684:CNE01840
uniprot id: Q5KGZ2
names: Similarity
messages: Belongs to the amidase family.

214684:CNJ03220
gene id: 214684:CNJ03220
uniprot id: Q5KA34
names: Subcellular Location Annotation
messages: Membrane

214684:CNA00640
gene id: 214684:CNA00640
uniprot id: P0CM92
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CTL (choline transporter-like) family.
messages: Cell membrane
messages: Probably involved in transport through the plasma membrane.

214684:CNB05640
gene id: 214684:CNB05640
uniprot id: Q5KLD7
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.

214684:CND00070
gene id: 214684:CND00070
uniprot id: Q5KJA2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

214684:CNA08340
gene id: 214684:CNA08340
uniprot id: Q5KMZ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

214684:CNE01030
gene id: 214684:CNE01030
uniprot id: Q5KH71
names: Subcellular Location Annotation
messages: Membrane

214684:CNI01590
gene id: 214684:CNI01590
uniprot id: Q5KBS3
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

214684:CNJ02220
gene id: 214684:CNJ02220
uniprot id: Q5KAC3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

214684:CNH00070
gene id: 214684:CNH00070
uniprot id: Q5KC79
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

214684:CND03840
gene id: 214684:CND03840
uniprot id: Q5KI85
names: Subcellular Location Annotation
messages: Membrane
messages: Vacuole membrane

214684:CNM00700
gene id: 214684:CNM00700
uniprot id: P0CN50
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-3 subunit E family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex.
messages: Cytoplasm

214684:CNI00460
gene id: 214684:CNI00460
uniprot id: Q5KC30
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAA ATPase family.
messages: Endosome membrane
messages: Membrane

214684:CNA03330
gene id: 214684:CNA03330
uniprot id: P40909
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Component of the 60S subunit of the ribosome.
messages: Cytoplasm
messages: Exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be involved in DNA repair; Lys-11-linked is involved in ERAD (endoplasmic reticulum-associated degradation) and in cell-cycle regulation; Lys-29-linked is involved in lysosomal degradation; Lys-33-linked is involved in kinase modification; Lys-48-linked is involved in protein degradation via the proteasome; Lys-63-linked is involved in endocytosis, and DNA-damage responses. Linear polymer chains formed via attachment by the initiator Met lead to cell signaling. Ubiquitin is usually conjugated to Lys residues of target proteins, however, in rare cases, conjugation to Cys or Ser residues has been observed. When polyubiquitin is free (unanchored-polyubiquitin), it also has distinct roles, such as in activation of protein kinases, and in signaling (By similarity).
messages: In the C-terminal section; belongs to the eukaryotic ribosomal protein eL40 family.
messages: In the N-terminal section; belongs to the ubiquitin family.
messages: Nucleus
messages: Part of the 60S ribosomal subunit.

214684:CND03780
gene id: 214684:CND03780
uniprot id: Q5KI91
names: Similarity
messages: Belongs to the bystin family.

214684:CNN00970
gene id: 214684:CNN00970
uniprot id: Q5K762
names: Function
names: Similarity
messages: Belongs to the protein prenyltransferase subunit alpha family.
messages: Catalyzes the transfer of a geranyl-geranyl moiety from geranyl-geranyl pyrophosphate to cysteines occuring in specific C-terminal amino acid sequences.

214684:CNL04690
gene id: 214684:CNL04690
uniprot id: Q5K8S2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CCC1 family.
messages: Membrane

214684:CNJ01020
gene id: 214684:CNJ01020
uniprot id: Q5KAP0
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

214684:CNK02390
gene id: 214684:CNK02390
uniprot id: Q5K9C9
names: Similarity
messages: Belongs to the prefoldin subunit alpha family.

214684:CNF00390
gene id: 214684:CNF00390
uniprot id: Q5KFV9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA polymerase beta' chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Nucleus

214684:CNB02830
gene id: 214684:CNB02830
uniprot id: Q5KM60
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associates with the pre-60S ribosomal particle.
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Component of the ribosome assembly machinery. Nuclear paralog of the ribosomal protein P0, it binds pre-60S subunits at an early stage of assembly in the nucleolus, and is replaced by P0 in cytoplasmic pre-60S subunits and mature 80S ribosomes.
messages: Cytoplasm
messages: nucleolus

214684:CND05400
gene id: 214684:CND05400
uniprot id: Q5KHT0
names: Function
names: PTM
names: Similarity
messages: Belongs to the eIF-5A family.
messages: Translation factor that promotes translation elongation and termination, particularly upon ribosome stalling at specific amino acid sequence contexts. Binds between the exit (E) and peptidyl (P) site of the ribosome and promotes rescue of stalled ribosome: specifically required for efficient translation of polyproline-containing peptides as well as other motifs that stall the ribosome. Acts as ribosome quality control (RQC) cofactor by joining the RQC complex to facilitate peptidyl transfer during CAT tailing step.
messages: eIF-5A seems to be the only eukaryotic protein to have a hypusine residue which is a post-translational modification of a lysine by the addition of a butylamino group.

214684:CNC05990
gene id: 214684:CNC05990
uniprot id: P0CM06
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the actin-binding proteins ADF family.
messages: Controls reversibly actin polymerization and depolymerization in a pH-sensitive manner. It has the ability to bind G- and F-actin in a 1:1 ratio of cofilin to actin. Binding to F-actin is regulated by tropomyosin. It is the major component of intranuclear and cytoplasmic actin rods. Required for accumulation of actin at the cell division site via depolymerizing actin at the cell ends. In association with myosin II has a role in the assembly of the contractile ring via severing actin filaments. Involved in the maintenance of the contractile ring once formed. In association with profilin and capping protein, has a role in the mitotic reorganization of the actin cytoskeleton (By similarity).
messages: Cytoplasm
messages: Nucleus matrix
messages: cytoskeleton

214684:CNF04790
gene id: 214684:CNF04790
uniprot id: Q5KEP0
names: Subcellular Location Annotation
messages: Membrane

214684:CNI04060
gene id: 214684:CNI04060
uniprot id: Q5KB22
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MGM101 family.
messages: mitochondrion nucleoid

214684:CNB03190
gene id: 214684:CNB03190
uniprot id: Q5KM29
names: Similarity
messages: Belongs to the CoA-transferase III family.

214684:CNJ02260
gene id: 214684:CNJ02260
uniprot id: Q5KAB9
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL14 family.

214684:CNL04930
gene id: 214684:CNL04930
uniprot id: Q5K8P7
names: Subcellular Location Annotation
messages: Nucleus

214684:CNB00600
gene id: 214684:CNB00600
uniprot id: Q5KMT0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the REI1 family.
messages: Cytoplasm

214684:CNA00930
gene id: 214684:CNA00930
uniprot id: Q5KQ04
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic release factor 1 family. Pelota subfamily.
messages: Component of the Dom34-Hbs1 complex, a complex that recognizes stalled ribosomes and triggers the No-Go Decay (NGD) pathway (PubMed:20890290). In the Dom34-Hbs1 complex, dom34 recognizes ribosomes stalled at the 3' end of an mRNA and engages stalled ribosomes by destabilizing mRNA in the mRNA channel. Following ribosome-binding, the Dom34-Hbs1 complex promotes the disassembly of stalled ribosomes, followed by degradation of damaged mRNAs as part of the NGD pathway.
messages: Cytoplasm

214684:CNC04840
gene id: 214684:CNC04840
uniprot id: Q5KJZ3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: A monovalent cation.
messages: Belongs to the folylpolyglutamate synthase family.
messages: Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis.
messages: Membrane
messages: Mitochondrion inner membrane

214684:CNI02310
gene id: 214684:CNI02310
uniprot id: Q5KBJ7
names: Similarity
messages: Belongs to the TEL2 family.

214684:CNK01430
gene id: 214684:CNK01430
uniprot id: P0CN26
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-B family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA polymerase II participates in chromosomal DNA replication.
messages: Heterotetramer. Consists of 4 subunits: POL2, DPB2, DPB3 and DPB4 (By similarity).
messages: Nucleus
messages: The CysA-type zinc finger is required for PCNA-binding.
messages: The CysB motif binds 1 4Fe-4S cluster and is required for the formation of polymerase complexes.

214684:CND04010
gene id: 214684:CND04010
uniprot id: Q5KI70
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

214684:CNC05170
gene id: 214684:CNC05170
uniprot id: P0CS10
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. TRM10 family.
messages: Cytoplasm
messages: Monomer.
messages: Nucleus
messages: S-adenosyl-L-methionine-dependent guanine N(1)-methyltransferase that catalyzes the formation of N(1)-methylguanine at position 9 (m1G9) in cytoplasmic tRNA.

214684:CNJ00430
gene id: 214684:CNJ00430
uniprot id: Q5KAU7
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

214684:CNC00830
gene id: 214684:CNC00830
uniprot id: Q5KL42
names: Similarity
messages: Belongs to the TCP-1 chaperonin family.

214684:CNH03010
gene id: 214684:CNH03010
uniprot id: Q5KD20
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

214684:CND05980
gene id: 214684:CND05980
uniprot id: Q5KHM2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

214684:CNE03860
gene id: 214684:CNE03860
uniprot id: Q5KGE9
names: Similarity
messages: Belongs to the MT-A70-like family.

214684:CNG04070
gene id: 214684:CNG04070
uniprot id: Q5KDG6
names: Subcellular Location Annotation
messages: Nucleus

214684:CNF04080
gene id: 214684:CNF04080
uniprot id: Q5KEV8
names: Function
names: Similarity
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.

214684:CNG02580
gene id: 214684:CNG02580
uniprot id: Q5KDW3
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

214684:CND05760
gene id: 214684:CND05760
uniprot id: Q5KHP6
names: Similarity
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.

214684:CNB02080
gene id: 214684:CNB02080
uniprot id: Q5KMD5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RFT1 family.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: May participate in the translocation of oligosaccharide from the cytoplasmic side to the lumenal side of the endoplasmic reticulum membrane.
messages: Membrane

214684:CNG03480
gene id: 214684:CNG03480
uniprot id: Q5KDM0
uniprot id: Q5KDM1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Binds 1 [3Fe-4S] cluster.
messages: Binds 1 [4Fe-4S] cluster.
messages: Component of complex II composed of four subunits: a flavoprotein (FP), an iron-sulfur protein (IP), and a cytochrome b composed of a large and a small subunit.
messages: Iron-sulfur protein (IP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).
messages: Mitochondrion inner membrane

214684:CNA00350
gene id: 214684:CNA00350
uniprot id: Q5KQ60
names: Function
names: Similarity
messages: Acts as a regulatory subunit of the 26S proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins.
messages: Belongs to the peptidase M67A family.

214684:CNE02690
gene id: 214684:CNE02690
uniprot id: Q5KGQ8
names: Similarity
messages: Belongs to the universal ribosomal protein uL3 family.

214684:CNB04750
gene id: 214684:CNB04750
uniprot id: Q5KLM4
names: Similarity
messages: Belongs to the amino acid/polyamine transporter 2 family.

214684:CNF00180
gene id: 214684:CNF00180
uniprot id: Q5KFY2
names: Subcellular Location Annotation
messages: Secreted

214684:CND02650
gene id: 214684:CND02650
uniprot id: P0CQ92
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-binding RNA helicase involved in ribosome assembly.
messages: Associates with pre-ribosomal particles.
messages: Belongs to the DEAD box helicase family. DDX27/DRS1 subfamily.
messages: The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.
messages: nucleolus

214684:CNG01370
gene id: 214684:CNG01370
uniprot id: Q5KE86
names: Subcellular Location Annotation
messages: Membrane

214684:CNK02990
gene id: 214684:CNK02990
uniprot id: Q5K970
names: Similarity
messages: Belongs to the VAMP-associated protein (VAP) (TC 9.B.17) family.

214684:CNE05340
gene id: 214684:CNE05340
uniprot id: Q5KG03
names: Subcellular Location Annotation
messages: Membrane

214684:CNB04990
gene id: 214684:CNB04990
uniprot id: Q5KLK0
names: Cofactor
names: Similarity
messages: Belongs to the MsrB Met sulfoxide reductase family.
messages: Binds 1 zinc ion per subunit.

214684:CNA00730
gene id: 214684:CNA00730
uniprot id: Q5KQ23
names: Similarity
messages: Belongs to the MAD1 family.

214684:CNF01860
gene id: 214684:CNF01860
uniprot id: Q5KFG2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1A family.
messages: Cytoplasm
messages: Nucleus
messages: The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits.

214684:CNE02790
gene id: 214684:CNE02790
uniprot id: Q5KGP8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OXA1/ALB3/YidC family.
messages: Membrane

214684:CNF00920
gene id: 214684:CNF00920
uniprot id: Q5KFQ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 22 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

214684:CNM02310
gene id: 214684:CNM02310
uniprot id: Q5K7I6
names: Subcellular Location Annotation
messages: Membrane

214684:CNE01720
gene id: 214684:CNE01720
uniprot id: Q5KH03
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

214684:CNC01680
gene id: 214684:CNC01680
uniprot id: Q5KKV8
names: Similarity
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.

214684:CNH00360
gene id: 214684:CNH00360
uniprot id: Q5KCA6
names: Similarity
messages: Belongs to the glycosyltransferase 32 family.

214684:CNC02320
gene id: 214684:CNC02320
uniprot id: Q5KKP4
names: Disruption Phenotype
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Abolishes LAC1 expression and activity during glucose starvation (PubMed:17040492). Abolishes laccase activity during calcium stress and iron stress (PubMed:17040492). Severely decreases laccase activity during copper stress (PubMed:17040492). Melanin absent from cell (PubMed:25972480). Decreases virulence in a mouse intravenous inoculation model of infection (PubMed:17040492).
messages: Belongs to the heat shock protein 70 family.
messages: Interacts with transcription factor HSF1 on chromatin.
messages: Nucleus
messages: Transcriptional coregulator that functions together with transcription factor HSF1 (PubMed:17040492). Positively regulates the expression of laccase LAC1 during glucose starvation (PubMed:17040492).

214684:CNL06440
gene id: 214684:CNL06440
uniprot id: Q5K8A0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EAF7 family.
messages: Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histone H4 and H2A. The NuA4 complex is also involved in DNA repair.
messages: Nucleus

214684:CNK02350
gene id: 214684:CNK02350
uniprot id: Q5K9D3
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.

214684:CND04380
gene id: 214684:CND04380
uniprot id: Q5KI33
names: Similarity
messages: Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.

214684:CNA07400
gene id: 214684:CNA07400
uniprot id: P0CN18
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DPH1/DPH2 family. DPH1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the first step of diphthamide biosynthesis, a post-translational modification of histidine which occurs in elongation factor 2. DPH1 and DPH2 transfer a 3-amino-3-carboxypropyl (ACP) group from S-adenosyl-L-methionine (SAM) to a histidine residue, the reaction is assisted by a reduction system comprising DPH3 and a NADH-dependent reductase, predominantly CBR1.
messages: Component of the 2-(3-amino-3-carboxypropyl)histidine synthase complex composed of DPH1, DPH2, DPH3 and a NADH-dependent reductase, predominantly CBR1.
messages: Cytoplasm

214684:CNI02680
gene id: 214684:CNI02680
uniprot id: Q5KBF9
names: Similarity
messages: Belongs to the UPF0057 (PMP3) family.

214684:CNK03340
gene id: 214684:CNK03340
uniprot id: Q5K938
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the V-ATPase proteolipid subunit family.
messages: Membrane
messages: Proton-conducting pore forming of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments.
messages: V-ATPase is a heteromultimeric enzyme composed of a peripheral catalytic V1 complex (components A to H) attached to an integral membrane V0 proton pore complex (components: a, c, c', c'', d, e, f and VOA1). The decameric c-ring forms the proton-conducting pore, and is composed of eight proteolipid subunits c, one subunit c' and one subunit c''.
messages: Vacuole membrane

214684:CNN01550
gene id: 214684:CNN01550
uniprot id: Q5K707
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

214684:CNC06210
gene id: 214684:CNC06210
uniprot id: Q5KJK6
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

214684:CNE04010
gene id: 214684:CNE04010
uniprot id: Q5KGD4
names: Subcellular Location Annotation
messages: Membrane

214684:CNE01860
gene id: 214684:CNE01860
uniprot id: Q5KGZ0
names: Subcellular Location Annotation
messages: Membrane

214684:CND04040
gene id: 214684:CND04040
uniprot id: Q5KI67
names: Similarity
messages: Belongs to the AAA ATPase family.

214684:CNH00110
gene id: 214684:CNH00110
uniprot id: Q5KC83
names: Subcellular Location Annotation
messages: Membrane

214684:CND02630
gene id: 214684:CND02630
uniprot id: P0CP54
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peroxidase family. Cytochrome c peroxidase subfamily.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.
messages: Forms a one-to-one complex with cytochrome c.
messages: Mitochondrion matrix

214684:CNC01300
gene id: 214684:CNC01300
uniprot id: Q5KKZ7
names: Subcellular Location Annotation
messages: Membrane

214684:CNB03860
gene id: 214684:CNB03860
uniprot id: Q5KLW1
names: Similarity
messages: Belongs to the PAPS reductase family. CysH subfamily.

214684:CNL05570
gene id: 214684:CNL05570
uniprot id: Q5K8I4
names: Similarity
messages: Belongs to the COG2 family.

214684:CNK02660
gene id: 214684:CNK02660
uniprot id: Q5K9A2
names: Subcellular Location Annotation
messages: Membrane

214684:CNJ01230
gene id: 214684:CNJ01230
uniprot id: P0CS12
names: Similarity
names: Subunit
messages: Belongs to the thymidylate synthase family.
messages: Homodimer.

214684:CNE02190
gene id: 214684:CNE02190
uniprot id: Q5KGV7
names: Subcellular Location Annotation
messages: nucleolus

214684:CNG04410
gene id: 214684:CNG04410
uniprot id: Q5KDD2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 13 family.
messages: Component of the SRB8-11 complex, which itself associates with the Mediator complex.
messages: Component of the SRB8-11 complex. The SRB8-11 complex is a regulatory module of the Mediator complex which is itself involved in regulation of basal and activated RNA polymerase II-dependent transcription. The SRB8-11 complex may be involved in the transcriptional repression of a subset of genes regulated by Mediator. It may inhibit the association of the Mediator complex with RNA polymerase II to form the holoenzyme complex.
messages: Nucleus

214684:CNN02250
gene id: 214684:CNN02250
uniprot id: Q5K6U4
names: Similarity
messages: Belongs to the inositol phosphokinase (IPK) family.

214684:CNN02160
gene id: 214684:CNN02160
uniprot id: Q5K6V3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GPN-loop GTPase family.
messages: Binds to RNA polymerase II (RNAPII).
messages: Small GTPase required for proper localization of RNA polymerase II and III (RNAPII and RNAPIII). May act at an RNAP assembly step prior to nuclear import.

214684:CNG00170
gene id: 214684:CNG00170
uniprot id: Q5KEK6
names: Function
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.
messages: Catalyzes the activation of alpha-aminoadipate by ATP-dependent adenylation and the reduction of activated alpha-aminoadipate by NADPH. The activated alpha-aminoadipate is bound to the phosphopantheinyl group of the enzyme itself before it is reduced to (S)-2-amino-6-oxohexanoate.

214684:CNJ01150
gene id: 214684:CNJ01150
uniprot id: P0CR38
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SEC23/SEC24 family. SEC23 subfamily.
messages: COPII-coated vesicle membrane
messages: Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules (By similarity).
messages: Cytoplasm
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: The COPII coat is composed of at least 5 proteins: the SEC23/24 complex, the SEC13/31 complex, and the protein SAR1.

214684:CNB02520
gene id: 214684:CNB02520
uniprot id: Q5KM91
names: Similarity
messages: Belongs to the HARBI1 family.

214684:CNL05490
gene id: 214684:CNL05490
uniprot id: Q5K8J2
names: Similarity
messages: Belongs to the peptidase A1 family.

214684:CNC06100
gene id: 214684:CNC06100
uniprot id: Q5KJL6
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS19 family.

214684:CNF03950
gene id: 214684:CNF03950
uniprot id: Q5KEW8
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the myo-inositol oxygenase family.
messages: Binds 2 iron ions per subunit.
messages: Cytoplasm

214684:CNC06200
gene id: 214684:CNC06200
uniprot id: Q5KJK7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ERG28 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

214684:CNE02560
gene id: 214684:CNE02560
uniprot id: Q5KGS1
names: Similarity
messages: Belongs to the small GTPase superfamily. Rab family.

214684:CNB04850
gene id: 214684:CNB04850
uniprot id: Q5KLL4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1A family.
messages: Cytoplasm
messages: Nucleus
messages: The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits.

214684:CNJ01000
gene id: 214684:CNJ01000
uniprot id: Q5KAP2
names: Similarity
messages: Belongs to the AAA ATPase family.

214684:CND01240
gene id: 214684:CND01240
uniprot id: Q5KIZ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 39 family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Transfers mannose from Dol-P-mannose to Ser or Thr residues on proteins.

214684:CNH02620
gene id: 214684:CNH02620
uniprot id: Q5KCY2
names: Similarity
messages: Belongs to the folylpolyglutamate synthase family.

214684:CNF00430
gene id: 214684:CNF00430
uniprot id: P0CP80
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cyclophilin-type PPIase family. PPIase D subfamily.
messages: Cytoplasm
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides (By similarity).

214684:CNN00500
gene id: 214684:CNN00500
uniprot id: Q5K7A8
names: Similarity
messages: Belongs to the MYST (SAS/MOZ) family.

214684:CNG03390
gene id: 214684:CNG03390
uniprot id: Q5KDM8
names: Similarity
messages: Belongs to the yippee family.

214684:CND04290
gene id: 214684:CND04290
uniprot id: Q5KI42
names: Similarity
messages: Belongs to the small GTPase superfamily. Arf family.

214684:CNB02090
gene id: 214684:CNB02090
uniprot id: Q5KMD4
names: Subcellular Location Annotation
messages: Membrane

214684:CNM01820
gene id: 214684:CNM01820
uniprot id: Q5K7N5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as component of the MCM2-7 complex (MCM complex) which is the replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity.
messages: Belongs to the MCM family.
messages: Component of the MCM2-7 complex.
messages: Nucleus

214684:CNL06790
gene id: 214684:CNL06790
uniprot id: Q5K865
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pex2/pex10/pex12 family.
messages: Component of the PEX2-PEX10-PEX12 retrotranslocation channel, composed of PEX2, PEX10 and PEX12.
messages: Membrane
messages: Peroxisome membrane

214684:CNG00410
gene id: 214684:CNG00410
uniprot id: Q5KEI5
names: Similarity
messages: Belongs to the DAMOX/DASOX family.

214684:CNI03270
gene id: 214684:CNI03270
uniprot id: Q5KBA0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
messages: Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).
messages: Mitochondrion inner membrane

214684:CNL05670
gene id: 214684:CNL05670
uniprot id: Q5K8H5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H4 family.
messages: Chromosome
messages: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

214684:CNJ00750
gene id: 214684:CNJ00750
uniprot id: P0CO30
names: Function
names: Similarity
messages: Belongs to the MBF1 family.
messages: Transcriptional coactivator that stimulates GCN4-dependent transcriptional activity by bridging the DNA-binding region of GCN4 and TBP (SPT15), thereby recruiting TBP to GCN4-bound promoters. Involved in induction of the ribosome quality control (RQC) pathway; a pathway that degrades nascent peptide chains during problematic translation. Required to prevent stalled ribosomes from frameshifting.

214684:CNK01330
gene id: 214684:CNK01330
uniprot id: Q5K9N7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family.
messages: Membrane

214684:CNA02890
gene id: 214684:CNA02890
uniprot id: Q5KPG4
names: Similarity
messages: Belongs to the AHA1 family.

214684:CNC06990
gene id: 214684:CNC06990
uniprot id: Q5KJC9
names: Similarity
messages: Belongs to the universal ribosomal protein uL11 family.

214684:CNC03840
gene id: 214684:CNC03840
uniprot id: Q5KK91
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase g subunit family.
messages: Membrane

214684:CNI04110
gene id: 214684:CNI04110
uniprot id: Q5KB17
names: Similarity
messages: Belongs to the protein kinase superfamily.

214684:CNA02550
gene id: 214684:CNA02550
uniprot id: Q5KPJ7
names: Similarity
messages: Belongs to the IPP isomerase type 1 family.

214684:CNE03710
gene id: 214684:CNE03710
uniprot id: P0CS26
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the VPS27 family.
messages: Both IUM domains are necessary for efficient binding to ubiquitin.
messages: Component of the ESCRT-0 complex composed of HSE1 and VPS27.
messages: Component of the ESCRT-0 complex which is the sorting receptor for ubiquitinated cargo proteins at the multivesicular body (MVB) and recruits ESCRT-I to the MVB outer membrane.
messages: Endosome membrane
messages: The FYVE domain is involved in the binding to phosphatidylinositol 3-phosphate (PtdIns(3)P) which is required for the association to endosomal membranes.

214684:CNB01410
gene id: 214684:CNB01410
uniprot id: Q5KMK2
names: Subcellular Location Annotation
messages: Membrane

214684:CND06070
gene id: 214684:CND06070
uniprot id: Q5KHL3
names: Subcellular Location Annotation
messages: Membrane

214684:CNH00450
gene id: 214684:CNH00450
uniprot id: Q5KCB5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

214684:CNE01200
gene id: 214684:CNE01200
uniprot id: Q5KH56
names: Subcellular Location Annotation
messages: nucleolus

214684:CNL05470
gene id: 214684:CNL05470
uniprot id: Q5K8J3
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

214684:CNA00680
gene id: 214684:CNA00680
uniprot id: Q5KQ28
names: Subcellular Location Annotation
messages: Membrane

214684:CNM02570
gene id: 214684:CNM02570
uniprot id: Q5K7G0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

214684:CND06120
gene id: 214684:CND06120
uniprot id: Q5KHK8
names: Similarity
messages: In the C-terminal section; belongs to the histidinol dehydrogenase family.

214684:CNF04640
gene id: 214684:CNF04640
uniprot id: Q5KEQ5
names: Similarity
messages: Belongs to the 5'-AMP-activated protein kinase beta subunit family.

214684:CNE00550
gene id: 214684:CNE00550
uniprot id: Q5KHC1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-3 subunit H family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex.
messages: Cytoplasm

214684:CNF01370
gene id: 214684:CNF01370
uniprot id: Q5KFL2
names: Similarity
messages: Belongs to the iron/ascorbate-dependent oxidoreductase family.

214684:CNA07390
gene id: 214684:CNA07390
uniprot id: Q5KN82
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

214684:CNC03700
gene id: 214684:CNC03700
uniprot id: Q5KKA5
names: Function
names: Similarity
messages: Belongs to the UDPGP type 1 family.
messages: Plays a central role as a glucosyl donor in cellular metabolic pathways.

214684:CNK00470
gene id: 214684:CNK00470
uniprot id: Q5K9W5
names: Subcellular Location Annotation
messages: Mitochondrion inner membrane
messages: Mitochondrion intermembrane space

214684:CNE00610
gene id: 214684:CNE00610
uniprot id: Q5KHB5
names: Similarity
messages: Belongs to the calreticulin family.

214684:CNB04090
gene id: 214684:CNB04090
uniprot id: Q5KLT9
uniprot id: Q5KLU0
names: Cofactor
names: Similarity
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

214684:CNH03360
gene id: 214684:CNH03360
uniprot id: Q5KD55
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

214684:CNK03230
gene id: 214684:CNK03230
uniprot id: Q5K947
names: Similarity
messages: Belongs to the universal ribosomal protein uS7 family.

214684:CNB00540
gene id: 214684:CNB00540
uniprot id: Q5KMT6
names: Subcellular Location Annotation
messages: nucleolus

214684:CNH02550
gene id: 214684:CNH02550
uniprot id: Q5KCX5
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

214684:CNC03200
gene id: 214684:CNC03200
uniprot id: Q5KKF3
names: Similarity
messages: Belongs to the eukaryotic initiation factor 4E family.

214684:CNF00600
gene id: 214684:CNF00600
uniprot id: Q5KFT7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

214684:CNC06350
gene id: 214684:CNC06350
uniprot id: Q5KJJ3
names: Similarity
messages: Belongs to the SF3A3 family.

214684:CNB00560
gene id: 214684:CNB00560
uniprot id: P0CO02
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetylation of N-terminal lysines and particularly formation of H2BK11ac has a positive effect on transcription.
messages: Belongs to the histone H2B family.
messages: Chromosome
messages: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
messages: Monoubiquitinated by the UBC2-BRE1 complex to form H2BK123ub1. H2BK123ub1 gives a specific tag for epigenetic transcriptional activation and is also prerequisite for H3K4me and H3K79me formation. H2BK123ub1 also modulates the formation of double-strand breaks during meiosis and is a prerequisite for DNA-damage checkpoint activation (By similarity).
messages: Nucleus
messages: Phosphorylated to form H2BS10ph during progression through meiotic prophase. May be correlated with chromosome condensation (By similarity).
messages: Sumoylation to form H2BK6su occurs preferentially near the telomeres and represses gene transcription.
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.
messages: To ensure consistency between histone entries, we follow the 'Brno' nomenclature for histone modifications, with positions referring to those used in the literature for the 'closest' model organism. Due to slight variations in histone sequences between organisms and to the presence of initiator methionine in UniProtKB/Swiss-Prot sequences, the actual positions of modified amino acids in the sequence generally differ. In this entry the following conventions are used: H2BK6ac = acetylated Lys-9; H2BK6su = sumoylated Lys-9; H2BS10ph = phosphorylated Ser-13; H2BK11ac = acetylated Lys-17; H2BK123ub1 = monoubiquitinated Lys-134.

214684:CNI02950
gene id: 214684:CNI02950
uniprot id: P0CS38
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat HIR1 family.
messages: Nucleus
messages: Required for replication-independent chromatin assembly and for the periodic repression of histone gene transcription during the cell cycle.

214684:CNB04580
gene id: 214684:CNB04580
uniprot id: Q5KLP2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase d subunit family.
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: Mitochondrion inner membrane

214684:CNA01360
gene id: 214684:CNA01360
uniprot id: Q5KPW1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEC16 family.
messages: Endoplasmic reticulum membrane
messages: Involved in the initiation of assembly of the COPII coat required for the formation of transport vesicles from the endoplasmic reticulum (ER) and the selection of cargo molecules. Also involved in autophagy.

214684:CNF02980
gene id: 214684:CNF02980
uniprot id: Q5KF50
names: Similarity
messages: Belongs to the gamma-BBH/TMLD family.

214684:CNC06340
gene id: 214684:CNC06340
uniprot id: Q5KJJ4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Aminocarboxypropyltransferase that catalyzes the aminocarboxypropyl transfer on pseudouridine at position 1191 (Psi1191) in 18S rRNA. It constitutes the last step in biosynthesis of the hypermodified N1-methyl-N3-(3-amino-3-carboxypropyl) pseudouridine (m1acp3-Psi) conserved in eukaryotic 18S rRNA.
messages: Belongs to the TDD superfamily. TSR3 family.
messages: Cytoplasm
messages: Nucleus

214684:CNK01050
gene id: 214684:CNK01050
uniprot id: Q5K9R3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 6-phosphogluconate dehydrogenase family.
messages: Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
messages: Homodimer.

214684:CNG02480
gene id: 214684:CNG02480
uniprot id: Q5KDX3
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Eukaryotic type I sub-subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer). Plays a central role in phospholipid metabolism and in the interorganelle trafficking of phosphatidylserine.
messages: Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The autoendoproteolytic cleavage occurs by a canonical serine protease mechanism, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain. During this reaction, the Ser that is part of the protease active site of the proenzyme becomes the pyruvoyl prosthetic group, which constitutes an essential element of the active site of the mature decarboxylase.
messages: Mitochondrion inner membrane

214684:CNG03550
gene id: 214684:CNG03550
uniprot id: Q5KDL3
names: Similarity
messages: Belongs to the AAA ATPase family.

214684:CNJ02890
gene id: 214684:CNJ02890
uniprot id: Q5KA65
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the XPT1 family.
messages: Golgi apparatus membrane
messages: Xylosylphosphotransferase that is specific for UDP-xylose as a donor and mannose as an acceptor to form a xylose-alpha-1-phosphate-6-mannose linkage. Functions in the O-glycosylation of proteins en route through the secretory pathway (By similarity).

214684:CNC02720
gene id: 214684:CNC02720
uniprot id: Q5KKK2
names: Similarity
messages: Belongs to the iron/ascorbate-dependent oxidoreductase family.

214684:CNG01290
gene id: 214684:CNG01290
uniprot id: Q5KE94
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TCP-1 chaperonin family.
messages: Cytoplasm
messages: Heterooligomeric complex of about 850 to 900 kDa that forms two stacked rings, 12 to 16 nm in diameter.

214684:CNL03660
gene id: 214684:CNL03660
uniprot id: Q5K924
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

214684:CNB00030
gene id: 214684:CNB00030
uniprot id: Q5KMY7
names: Similarity
names: Subunit
messages: Belongs to the uroporphyrinogen decarboxylase family.
messages: Homodimer.

214684:CNG02540
gene id: 214684:CNG02540
uniprot id: Q5KDW7
names: Similarity
messages: Belongs to the VPS52 family.

214684:CNC05150
gene id: 214684:CNC05150
uniprot id: Q5KJW3
names: Similarity
messages: Belongs to the cytochrome c oxidase subunit 6B family.

214684:CND06200
gene id: 214684:CND06200
uniprot id: Q5KHK0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class VI-like SAM-binding methyltransferase superfamily. PEMT/PEM2 methyltransferase family.
messages: Catalyzes the second two steps of the methylation pathway of phosphatidylcholine biosynthesis, the SAM-dependent methylation of phosphatidylmonomethylethanolamine (PMME) to phosphatidyldimethylethanolamine (PDME) and of PDME to phosphatidylcholine (PC).
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Mitochondrion membrane

214684:CNE04590
gene id: 214684:CNE04590
uniprot id: Q5KG76
names: Similarity
messages: Belongs to the IUNH family.

214684:CNF02760
gene id: 214684:CNF02760
uniprot id: Q5KF72
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

214684:CND03700
gene id: 214684:CND03700
uniprot id: P0CR98
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the small Tim family.
messages: Heterohexamer; composed of 3 copies of TIM9 and 3 copies of TIM10, named soluble 70 kDa complex. Associates directly with the TIM22 complex, whose core is composed of TIM22 and TIM54. Interacts with the transmembrane regions of multi-pass transmembrane proteins in transit (By similarity).
messages: Mitochondrial intermembrane chaperone that participates in the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space (By similarity).
messages: Mitochondrion inner membrane
messages: The twin CX3C motif contains 4 conserved Cys residues that form 2 disulfide bonds in the mitochondrial intermembrane space. However, during the transit of TIM10 from cytoplasm into mitochondrion, the Cys residues probably coordinate zinc, thereby preventing folding and allowing its transfer across mitochondrial outer membrane (By similarity).

214684:CNM01690
gene id: 214684:CNM01690
uniprot id: Q5K7P9
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.

214684:CNC04700
gene id: 214684:CNC04700
uniprot id: Q5KK07
names: Cofactor
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.

214684:CNH02060
gene id: 214684:CNH02060
uniprot id: P0CO80
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MMM1 family.
messages: Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria. The MDM12-MMM1 subcomplex functions in the major beta-barrel assembly pathway that is responsible for biogenesis of all outer membrane beta-barrel proteins, and acts in a late step after the SAM complex. The MDM10-MDM12-MMM1 subcomplex further acts in the TOM40-specific pathway after the action of the MDM12-MMM1 complex. Essential for establishing and maintaining the structure of mitochondria and maintenance of mtDNA nucleoids.
messages: Endoplasmic reticulum membrane
messages: Homodimer. Component of the ER-mitochondria encounter structure (ERMES) or MDM complex, composed of MMM1, MDM10, MDM12 and MDM34. A MMM1 homodimer associates with one molecule of MDM12 on each side in a pairwise head-to-tail manner, and the SMP-LTD domains of MMM1 and MDM12 generate a continuous hydrophobic tunnel for phospholipid trafficking.
messages: The SMP-LTD domain is a barrel-like domain that can bind various types of glycerophospholipids in its interior and mediate their transfer between two adjacent bilayers.

214684:CNA03030
gene id: 214684:CNA03030
uniprot id: Q5KPF0
names: Function
names: Similarity
messages: Belongs to the ARPC5 family.
messages: Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development.

214684:CNK00950
gene id: 214684:CNK00950
uniprot id: Q5K9S3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ELP3 family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalytic tRNA acetyltransferase subunit of the elongator complex, which is required for multiple tRNA modifications, including mcm5U (5-methoxycarbonylmethyl uridine), mcm5s2U (5-methoxycarbonylmethyl-2-thiouridine), and ncm5U (5-carbamoylmethyl uridine). In the elongator complex, acts as a tRNA uridine(34) acetyltransferase by mediating formation of carboxymethyluridine in the wobble base at position 34 in tRNAs.

214684:CNE01440
gene id: 214684:CNE01440
uniprot id: P0CM66
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CGR1 family.
messages: Involved in nucleolar integrity and required for processing of the pre-rRNA for the 60S ribosome subunit.
messages: nucleolus

214684:CNG02920
gene id: 214684:CNG02920
uniprot id: Q5KDS7
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL24 family.

214684:CNI02830
gene id: 214684:CNI02830
uniprot id: Q5KBE4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the nucleoporin Nup84/Nup107 family.
messages: Functions as a component of the nuclear pore complex (NPC).
messages: Nucleus membrane
messages: Part of the nuclear pore complex (NPC).
messages: nuclear pore complex

214684:CNN02370
gene id: 214684:CNN02370
uniprot id: Q5K6T2
names: Similarity
messages: Belongs to the pirin family.

214684:CNI03490
gene id: 214684:CNI03490
uniprot id: Q5KB77
names: Similarity
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.

214684:CNK01650
gene id: 214684:CNK01650
uniprot id: Q5K9K4
names: Subcellular Location Annotation
messages: Nucleus

214684:CNC03360
gene id: 214684:CNC03360
uniprot id: Q5KKD7
names: Similarity
messages: Belongs to the CNOT2/3/5 family.

214684:CNK01780
gene id: 214684:CNK01780
uniprot id: Q5K9I8
names: Similarity
messages: Belongs to the pirin family.

214684:CND02990
gene id: 214684:CND02990
uniprot id: Q5KIH1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Su(H) family.
messages: Nucleus

214684:CNL05560
gene id: 214684:CNL05560
uniprot id: Q5K8I5
names: Similarity
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.

214684:CND05890
gene id: 214684:CND05890
uniprot id: Q5KHN2
names: Similarity
messages: Belongs to the HARBI1 family.

214684:CNM01570
gene id: 214684:CNM01570
uniprot id: Q5K7R1
names: Similarity
messages: Belongs to the COG4 family.

214684:CNE03430
gene id: 214684:CNE03430
uniprot id: Q5KGJ1
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.

214684:CNB05600
gene id: 214684:CNB05600
uniprot id: Q5KLE1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OST3/OST6 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

214684:CNH03240
gene id: 214684:CNH03240
uniprot id: Q5KD44
names: Similarity
messages: Belongs to the NipSnap family.

214684:CNE04440
gene id: 214684:CNE04440
uniprot id: Q5KG91
names: Similarity
messages: Belongs to the nucleosome assembly protein (NAP) family.

214684:CNK01460
gene id: 214684:CNK01460
uniprot id: P0CN52
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-3 subunit G family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex.
messages: Cytoplasm
messages: RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. This subunit can bind 18S rRNA.

214684:CNA02090
gene id: 214684:CNA02090
uniprot id: Q5KPN8
names: Similarity
messages: Belongs to the synaptobrevin family.

214684:CNM01450
gene id: 214684:CNM01450
uniprot id: Q5K7S3
names: Cofactor
messages: Binds 1 Fe(2+) ion per subunit.

214684:CNA05300
gene id: 214684:CNA05300
uniprot id: Q5KNU4
names: Subcellular Location Annotation
messages: Membrane

214684:CNG02760
gene id: 214684:CNG02760
uniprot id: P0CS00
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the small Tim family.
messages: Heterohexamer; composed of 3 copies of TIM8 and 3 copies of TIM13, named soluble 70 kDa complex. Associates with the TIM22 complex, whose core is composed of TIM22 and TIM54. Interacts with the transmembrane regions of multi-pass transmembrane proteins in transit (By similarity).
messages: Mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space. The TIM8-TIM13 complex is non essential and only mediates the import of few proteins, while the predominant TIM9-TIM10 70 kDa complex is crucial and mediates the import of much more proteins (By similarity).
messages: Mitochondrion inner membrane
messages: The twin CX3C motif contains 4 conserved Cys residues that form 2 disulfide bonds in the mitochondrial intermembrane space. However, during the transit of TIM13 from cytoplasm into mitochondrion, the Cys residues probably coordinate zinc, thereby preventing folding and allowing its transfer across mitochondrial outer membrane (By similarity).

214684:CNE01560
gene id: 214684:CNE01560
uniprot id: Q5KH19
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Cytoplasm
messages: Maintains high levels of reduced glutathione in the cytosol.

214684:CNE00510
gene id: 214684:CNE00510
uniprot id: Q5KHC6
names: Similarity
messages: Belongs to the SNF2/RAD54 helicase family.

214684:CNF00500
gene id: 214684:CNF00500
uniprot id: Q5KFU8
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.

214684:CNH02890
gene id: 214684:CNH02890
uniprot id: Q5KD08
names: Similarity
messages: Belongs to the peptidase C19 family.

214684:CNA07930
gene id: 214684:CNA07930
uniprot id: P0CO54
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATG8 family.
messages: The C-terminal 9 residues are removed to expose Gly-117 at the C-terminus. The C-terminal Gly is then amidated with phosphatidylethanolamine by an activating system similar to that for ubiquitin.
messages: Ubiquitin-like modifier involved in autophagosomes formation. With ATG4, mediates the delivery of the autophagosomes to the vacuole via the microtubule cytoskeleton. Required for selective autophagic degradation of the nucleus (nucleophagy) as well as for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production. Participates also in membrane fusion events that take place in the early secretory pathway. Also involved in endoplasmic reticulum-specific autophagic process and is essential for the survival of cells subjected to severe ER stress. The ATG8-PE conjugate mediates tethering between adjacent membranes and stimulates membrane hemifusion, leading to expansion of the autophagosomal membrane during autophagy.
messages: Vacuole membrane
messages: autophagosome membrane

214684:CNA04520
gene id: 214684:CNA04520
uniprot id: Q5KP18
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the COA3 family.
messages: Component of 250-400 kDa complexes called cytochrome oxidase assembly intermediates or COA complexes.
messages: Membrane
messages: Required for assembly of cytochrome c oxidase (complex IV).

214684:CND01000
gene id: 214684:CND01000
uniprot id: P0CO82
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MON1/SAND family.
messages: Prevacuolar compartment membrane
messages: Required for multiple vacuole delivery pathways including the cytoplasm to vacuole transport (Cvt), autophagy, pexophagy and endocytosis.
messages: Vacuole membrane
messages: multivesicular body membrane

214684:CNJ01420
gene id: 214684:CNJ01420
uniprot id: Q5KAK1
names: Subcellular Location Annotation
messages: Membrane

214684:CNC05270
gene id: 214684:CNC05270
uniprot id: Q5KJV1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

214684:CNM01890
gene id: 214684:CNM01890
uniprot id: Q5K7M8
names: Cofactor
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. NagA family.
messages: Binds 1 divalent metal cation per subunit.

214684:CNJ02710
gene id: 214684:CNJ02710
uniprot id: Q5KA75
names: Subcellular Location Annotation
messages: Membrane

214684:CND05700
gene id: 214684:CND05700
uniprot id: Q5KHQ2
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL39 family.

214684:CNB00170
gene id: 214684:CNB00170
uniprot id: Q5KMX4
names: Similarity
messages: Belongs to the MNN1/MNT family.

214684:CNM01300
gene id: 214684:CNM01300
uniprot id: P0CN30
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

214684:CNM00350
gene id: 214684:CNM00350
uniprot id: Q5K827
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peroxin-14 family.
messages: Component of the PEX13-PEX14 docking complex, a translocon channel that specifically mediates the import of peroxisomal cargo proteins bound to PEX5 receptor. The PEX13-PEX14 docking complex forms a large import pore which can be opened to a diameter of about 9 nm. Mechanistically, PEX5 receptor along with cargo proteins associates with the PEX14 subunit of the PEX13-PEX14 docking complex in the cytosol, leading to the insertion of the receptor into the organelle membrane with the concomitant translocation of the cargo into the peroxisome matrix.
messages: Peroxisome membrane

214684:CNL04980
gene id: 214684:CNL04980
uniprot id: Q5K8P2
names: Similarity
messages: Belongs to the AB hydrolase superfamily. MetX family.

214684:CNC01080
gene id: 214684:CNC01080
uniprot id: Q5KL18
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLD2 family.
messages: Has a role in the initiation of DNA replication. Required at S-phase checkpoint.
messages: Nucleus

214684:CNI04340
gene id: 214684:CNI04340
uniprot id: P0CQ56
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the universal ribosomal protein uS2 family.
messages: Component of the small ribosomal subunit. Mature ribosomes consist of a small (40S) and a large (60S) subunit. The 40S subunit contains about 33 different proteins and 1 molecule of RNA (18S). The 60S subunit contains about 49 different proteins and 3 molecules of RNA (25S, 5.8S and 5S). Interacts with RPS21.
messages: Cytoplasm
messages: Required for the assembly and/or stability of the 40S ribosomal subunit. Required for the processing of the 20S rRNA-precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits.

214684:CNF01920
gene id: 214684:CNF01920
uniprot id: Q5KFF6
names: Similarity
messages: Belongs to the HARBI1 family.

214684:CNG01060
gene id: 214684:CNG01060
uniprot id: P0CP78
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cyclophilin-type PPIase family. PPIase B subfamily.
messages: Endoplasmic reticulum lumen
messages: Inhibited by cyclosporin A (CsA).
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides (By similarity).

214684:CNM01080
gene id: 214684:CNM01080
uniprot id: Q5K7W2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Catalyzes the exchange of ADP and ATP across the membrane.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Monomer.

214684:CNJ00300
gene id: 214684:CNJ00300
uniprot id: Q5KAV8
names: Similarity
messages: Belongs to the ERT1/acuK family.

214684:CND05960
gene id: 214684:CND05960
uniprot id: Q5KHM4
names: Similarity
messages: Belongs to the iron/ascorbate-dependent oxidoreductase family.

214684:CNF01680
gene id: 214684:CNF01680
uniprot id: Q5KFI0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase PH family.
messages: nucleolus

214684:CNB05500
gene id: 214684:CNB05500
uniprot id: Q5KLF1
names: Similarity
messages: Belongs to the RutC family.

214684:CNE04840
gene id: 214684:CNE04840
uniprot id: Q5KG51
names: Subcellular Location Annotation
messages: Membrane

214684:CNB01730
gene id: 214684:CNB01730
uniprot id: Q5KMH0
names: Similarity
messages: Belongs to the alpha-ketoglutarate dehydrogenase family.

214684:CNA00510
gene id: 214684:CNA00510
uniprot id: Q5KQ45
names: Similarity
messages: Belongs to the citrate synthase family.

214684:CNI01310
gene id: 214684:CNI01310
uniprot id: Q5KBV0
names: Subcellular Location Annotation
messages: Membrane

214684:CNA03830
gene id: 214684:CNA03830
uniprot id: P0CN80
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SLX1 family.
messages: Catalytic subunit of the SLX1-SLX4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA.
messages: Forms a heterodimer with SLX4.
messages: Nucleus

214684:CNF02930
gene id: 214684:CNF02930
uniprot id: Q5KF55
names: Subcellular Location Annotation
messages: Membrane

214684:CNL06570
gene id: 214684:CNL06570
uniprot id: Q5K888
names: Similarity
messages: Belongs to the UFD1 family.

214684:CNL06220
gene id: 214684:CNL06220
uniprot id: Q5K8C2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TVP38/TMEM64 family.
messages: Golgi membrane protein involved in vesicular trafficking and spindle migration.
messages: Membrane

214684:CNG02300
gene id: 214684:CNG02300
uniprot id: Q5KDZ2
names: Similarity
messages: Belongs to the MUB1/samB family.

214684:CNM01720
gene id: 214684:CNM01720
uniprot id: Q5K7P6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the esterase D family.
messages: Cytoplasm
messages: Serine hydrolase involved in the detoxification of formaldehyde.

214684:CNG04630
gene id: 214684:CNG04630
uniprot id: Q5KDB5
names: Subcellular Location Annotation
messages: Membrane

214684:CNA02660
gene id: 214684:CNA02660
uniprot id: Q5KPI7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAP-alpha family.
messages: Endoplasmic reticulum membrane
messages: Membrane

214684:CNN02060
gene id: 214684:CNN02060
uniprot id: Q5K6W3
names: Similarity
messages: Belongs to the amidase family.

214684:CNA06030
gene id: 214684:CNA06030
uniprot id: Q5KNL9
names: Similarity
messages: Belongs to the glycosyl hydrolase 5 (cellulase A) family.

214684:CNA08220
gene id: 214684:CNA08220
uniprot id: Q5KN02
names: Similarity
messages: Belongs to the SURF6 family.

214684:CND04540
gene id: 214684:CND04540
uniprot id: Q5KI17
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase M16 family. PreP subfamily.
messages: Mitochondrion intermembrane space
messages: Mitochondrion matrix
messages: Monomer and homodimer; homodimerization is induced by binding of the substrate.

214684:CNK01070
gene id: 214684:CNK01070
uniprot id: Q5K9R1
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate 1-epimerase family.
messages: Catalyzes the interconversion between the alpha and beta anomers from at least three hexose 6-phosphate sugars (Glc6P, Gal6P, and Man6P).

214684:CNJ02270
gene id: 214684:CNJ02270
uniprot id: Q5KAB8
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 2 subfamily.

214684:CNE04490
gene id: 214684:CNE04490
uniprot id: Q5KG85
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sphingosine N-acyltransferase family.
messages: Membrane

214684:CNC02590
gene id: 214684:CNC02590
uniprot id: Q5KKL7
names: Similarity
messages: Belongs to the glycosyl hydrolase 28 family.

214684:CNG00550
gene id: 214684:CNG00550
uniprot id: Q5KEH0
names: Cofactor
names: Similarity
messages: Belongs to the arginase family.
messages: Binds 2 manganese ions per subunit.

214684:CNG02210
gene id: 214684:CNG02210
uniprot id: Q5KE02
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fungal cytochrome c oxidase subunit 7a family.
messages: Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.
messages: Membrane
messages: Mitochondrion inner membrane

214684:CNH00510
gene id: 214684:CNH00510
uniprot id: Q5KCC1
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

214684:CNF00740
gene id: 214684:CNF00740
uniprot id: Q5KFS4
names: Similarity
messages: Belongs to the pyrroline-5-carboxylate reductase family.

214684:CNJ01460
gene id: 214684:CNJ01460
uniprot id: Q5KAJ6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OST1 family.
messages: Component of the oligosaccharyltransferase (OST) complex.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All subunits are required for a maximal enzyme activity.

214684:CNC05400
gene id: 214684:CNC05400
uniprot id: Q5KJT8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Mediator complex subunit 22 family.
messages: Nucleus

214684:CNA08130
gene id: 214684:CNA08130
uniprot id: Q5KN11
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

214684:CNA00790
gene id: 214684:CNA00790
uniprot id: Q5KQ17
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRP4 family.
messages: Cytoplasm

214684:CNA01870
gene id: 214684:CNA01870
uniprot id: Q5KPQ9
names: Similarity
messages: Belongs to the adaptor complexes large subunit family.

214684:CNG01870
gene id: 214684:CNG01870
uniprot id: Q5KE36
names: Subcellular Location Annotation
messages: Membrane

214684:CNM01800
gene id: 214684:CNM01800
uniprot id: Q5K7N7
names: Similarity
messages: Belongs to the RMD1/sif2 family.

214684:CND05560
gene id: 214684:CND05560
uniprot id: Q5KHR6
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.

214684:CNF01190
gene id: 214684:CNF01190
uniprot id: Q5KFN1
names: Function
names: Similarity
messages: Belongs to the CKS family.
messages: Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function.

214684:CND02320
gene id: 214684:CND02320
uniprot id: Q5KIN6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the V-ATPase 116 kDa subunit family.
messages: Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.
messages: Membrane

214684:CNK03100
gene id: 214684:CNK03100
uniprot id: Q5K959
names: Similarity
messages: Belongs to the universal ribosomal protein uL14 family.

214684:CNF03900
gene id: 214684:CNF03900
uniprot id: Q5KEX3
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

214684:CNI00380
gene id: 214684:CNI00380
uniprot id: Q5KC37
names: Similarity
messages: Belongs to the DSD1 family.

214684:CNJ02410
gene id: 214684:CNJ02410
uniprot id: Q5KAA4
names: Subcellular Location Annotation
messages: Membrane

214684:CNJ00620
gene id: 214684:CNJ00620
uniprot id: Q5KAT0
names: Similarity
messages: Belongs to the peptidase S8 family.

214684:CNA06370
gene id: 214684:CNA06370
uniprot id: Q5KNI5
names: Subcellular Location Annotation
messages: Membrane
messages: Nucleus inner membrane

214684:CNE03020
gene id: 214684:CNE03020
uniprot id: Q5KGN2
names: Similarity
messages: Belongs to the AAA ATPase family.

214684:CNF02280
gene id: 214684:CNF02280
uniprot id: Q5KFB9
names: Function
names: Similarity
messages: Belongs to the ATPase alpha/beta chains family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

214684:CNC02310
gene id: 214684:CNC02310
uniprot id: P0CQ22
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Although related to the peptidase M24 family, this protein lacks conserved active site residues suggesting that it may lack peptidase activity.
messages: Belongs to the peptidase M24 family. SPT16 subfamily.
messages: Chromosome
messages: Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment of the nucleosome following the passage of RNA polymerase II (By similarity).
messages: Forms a stable heterodimer with POB3. The SPT16-POB3 dimer weakly associates with multiple molecules of NHP6 to form the FACT complex (By similarity).
messages: Nucleus

214684:CNG03610
gene id: 214684:CNG03610
uniprot id: Q5KDK7
names: Subcellular Location Annotation
messages: Nucleus

214684:CNG03540
gene id: 214684:CNG03540
uniprot id: P0CP48
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PAM17 family.
messages: Component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner.
messages: Component of the PAM complex, at least composed of mtHsp70 (SSC1), MGE1, TIM44, PAM16, PAM17 and PAM18.
messages: Mitochondrion inner membrane

214684:CNL05890
gene id: 214684:CNL05890
uniprot id: Q5K8F4
names: Similarity
messages: Belongs to the flavin monoamine oxidase family.

214684:CNB03020
gene id: 214684:CNB03020
uniprot id: Q5KM47
names: Similarity
messages: Belongs to the protein kinase superfamily.

214684:CNB04910
gene id: 214684:CNB04910
uniprot id: Q5KLK8
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M1 family.
messages: Binds 1 zinc ion per subunit.

214684:CNG04540
gene id: 214684:CNG04540
uniprot id: Q5KDC2
names: Similarity
messages: Belongs to the peptidase C19 family.

214684:CNK01350
gene id: 214684:CNK01350
uniprot id: Q5K9N5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic RPA43 RNA polymerase subunit family.
messages: nucleolus

214684:CNA07260
gene id: 214684:CNA07260
uniprot id: Q5KN95
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterodimer of an alpha and a beta subunit.
messages: Mitochondrion
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

214684:CNI02420
gene id: 214684:CNI02420
uniprot id: Q5KBI4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uricase family.
messages: Catalyzes the oxidation of uric acid to 5-hydroxyisourate, which is further processed to form (S)-allantoin.
messages: Peroxisome

214684:CNB00730
gene id: 214684:CNB00730
uniprot id: Q5KMR7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PET117 family.
messages: Mitochondrion

214684:CNG04290
gene id: 214684:CNG04290
uniprot id: Q5KDE3
names: Subcellular Location Annotation
messages: Membrane

214684:CNH03410
gene id: 214684:CNH03410
uniprot id: Q5KD61
names: Subcellular Location Annotation
messages: Nucleus

214684:CND05020
gene id: 214684:CND05020
uniprot id: Q5KHX0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm

214684:CNJ00080
gene id: 214684:CNJ00080
uniprot id: Q5KAX9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the multicopper oxidase family.
messages: Secreted

214684:CNH02700
gene id: 214684:CNH02700
uniprot id: Q5KCY9
names: Subcellular Location Annotation
messages: Membrane

214684:CNF00710
gene id: 214684:CNF00710
uniprot id: Q5KFS7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adaptor complexes small subunit family.
messages: Cytoplasmic vesicle membrane
messages: Membrane

214684:CNN00860
gene id: 214684:CNN00860
uniprot id: Q5K773
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

214684:CNG02750
gene id: 214684:CNG02750
uniprot id: Q5KDU5
names: Similarity
messages: Belongs to the LTV1 family.

214684:CND02200
gene id: 214684:CND02200
uniprot id: P0CM98
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associated with the spliceosome.
messages: Belongs to the CWC25 family.
messages: Involved in pre-mRNA splicing.
messages: Nucleus

214684:CNF04560
gene id: 214684:CNF04560
uniprot id: Q5KER3
names: Subcellular Location Annotation
messages: Membrane

214684:CNF03320
gene id: 214684:CNF03320
uniprot id: Q5KF26
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the WD repeat IPI3/WDR18 family.
messages: Component of the RIX1 complex required for processing of ITS2 sequences from 35S pre-rRNA.
messages: Component of the RIX1 complex, composed of IPI1, RIX1/IPI2 and IPI3 in a 1:2:2 stoichiometry. The complex interacts (via RIX1) with MDN1 (via its hexameric AAA ATPase ring) and the pre-60S ribosome particles.
messages: Nucleus

214684:CNA04700
gene id: 214684:CNA04700
uniprot id: Q5KP01
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

214684:CNI03340
gene id: 214684:CNI03340
uniprot id: Q5KB92
uniprot id: Q5KB93
names: Similarity
messages: Belongs to the actin family.

214684:CNA05330
gene id: 214684:CNA05330
uniprot id: Q5KNU1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the poly(A) polymerase family.
messages: Binds 2 magnesium ions. Also active with manganese.
messages: Nucleus
messages: Polymerase that creates the 3'-poly(A) tail of mRNA's.

214684:CNH01500
gene id: 214684:CNH01500
uniprot id: Q5KCL6
names: Similarity
messages: Belongs to the HARBI1 family.

214684:CND00340
gene id: 214684:CND00340
uniprot id: Q5KJ79
names: Similarity
messages: Belongs to the eukaryotic ATPase epsilon family.

214684:CNC00220
gene id: 214684:CNC00220
uniprot id: Q5KLA1
names: Function
names: Similarity
messages: Belongs to the CTP synthase family.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.

214684:CNJ01410
gene id: 214684:CNJ01410
uniprot id: Q5KAK2
names: Similarity
messages: Belongs to the universal ribosomal protein uL23 family.

214684:CNJ02200
gene id: 214684:CNJ02200
uniprot id: Q5KAC5
names: Cofactor
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Eukaryotic type II sub-subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer). Plays a central role in phospholipid metabolism and in the interorganelle trafficking of phosphatidylserine.
messages: Endosome membrane
messages: Golgi apparatus membrane
messages: Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The autoendoproteolytic cleavage occurs by a canonical serine protease mechanism, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain. During this reaction, the Ser that is part of the protease active site of the proenzyme becomes the pyruvoyl prosthetic group, which constitutes an essential element of the active site of the mature decarboxylase.
messages: The C2 domains have an essential, but non-catalytic function. They may facilitate interactions with other proteins and are required for lipid transport function.

214684:CNJ02340
gene id: 214684:CNJ02340
uniprot id: Q5KAB1
names: Similarity
messages: Belongs to the XPG/RAD2 endonuclease family.

214684:CNB00680
gene id: 214684:CNB00680
uniprot id: Q5KMS2
names: Similarity
messages: Belongs to the archaeal Rpo10/eukaryotic RPB10 RNA polymerase subunit family.

214684:CNG03880
gene id: 214684:CNG03880
uniprot id: Q5KDI3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAF12 family.
messages: Nucleus

214684:CNI03330
gene id: 214684:CNI03330
uniprot id: Q5KB94
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-dependent O-methyltransferase family.

214684:CNJ02940
gene id: 214684:CNJ02940
uniprot id: Q5KA61
names: Similarity
messages: Belongs to the sirtuin family. Class I subfamily.

214684:CNG04050
gene id: 214684:CNG04050
uniprot id: Q5KDG7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

214684:CNF02150
gene id: 214684:CNF02150
uniprot id: Q5KFD2
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein P1/P2 family.

214684:CNA04980
gene id: 214684:CNA04980
uniprot id: Q5KNX4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat peroxin-7 family.
messages: Peroxisome matrix
messages: cytosol

214684:CNG01100
gene id: 214684:CNG01100
uniprot id: Q5KEB3
names: Function
names: Similarity
messages: Belongs to the peroxiredoxin family.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively.

214684:CNB03360
gene id: 214684:CNB03360
uniprot id: Q5KM13
names: Subcellular Location Annotation
messages: Membrane

214684:CNG01410
gene id: 214684:CNG01410
uniprot id: Q5KE82
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

214684:CNC04310
gene id: 214684:CNC04310
uniprot id: Q5KK44
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.

214684:CNF04810
gene id: 214684:CNF04810
uniprot id: Q5KEN8
names: Subcellular Location Annotation
messages: Membrane

214684:CNE04210
gene id: 214684:CNE04210
uniprot id: Q5KGB5
names: Similarity
messages: Belongs to the small GTPase superfamily. Arf family.

214684:CNJ00800
gene id: 214684:CNJ00800
uniprot id: Q5KAR2
names: Similarity
names: Subunit
messages: Homotetramer.
messages: In the C-terminal section; belongs to the succinate/malate CoA ligase alpha subunit family.
messages: In the N-terminal section; belongs to the succinate/malate CoA ligase beta subunit family.

214684:CNK00110
gene id: 214684:CNK00110
uniprot id: Q5KA00
names: Similarity
messages: Belongs to the methyltransferase superfamily. Fibrillarin family.

214684:CNG03940
gene id: 214684:CNG03940
uniprot id: Q5KDH7
names: Subcellular Location Annotation
messages: Nucleus

214684:CNC04110
gene id: 214684:CNC04110
uniprot id: Q5KK64
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAA ATPase family. BCS1 subfamily.
messages: Membrane
messages: Mitochondrion inner membrane

214684:CNH02030
gene id: 214684:CNH02030
uniprot id: Q5KCS0
names: Similarity
messages: Belongs to the cytochrome b5 family.

214684:CNC05280
gene id: 214684:CNC05280
uniprot id: Q5KJV0
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

214684:CNB00070
gene id: 214684:CNB00070
uniprot id: Q5KMY3
names: Subcellular Location Annotation
messages: Mitochondrion

214684:CNC06460
gene id: 214684:CNC06460
uniprot id: P0CQ80
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: ATP-dependent RNA helicase involved in mRNA turnover, and more specifically in mRNA decapping. Is involved in G1/S DNA-damage checkpoint recovery, probably through the regulation of the translational status of a subset of mRNAs. May also have a role in translation and mRNA nuclear export (By similarity).
messages: Belongs to the DEAD box helicase family. DDX6/DHH1 subfamily.
messages: P-body
messages: The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.

214684:CNK01600
gene id: 214684:CNK01600
uniprot id: Q5K9L0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acts as an adapter for the XPO1/CRM1-mediated export of the 60S ribosomal subunit.
messages: Belongs to the NMD3 family.
messages: Cytoplasm
messages: Nucleus

214684:CND04900
gene id: 214684:CND04900
uniprot id: P0CQ08
names: Activity Regulation
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase C19 family. PAN2 subfamily.
messages: Binds 2 metal cations per subunit in the catalytic exonuclease domain.
messages: Catalytic subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein PAB1. PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenylation-dependent mRNA decaping and subsequent 5'-3' exonucleolytic degradation by XRN1. May also be involved in post-transcriptional maturation of mRNA poly(A) tails.
messages: Contains a pseudo-UCH domain. This ubiquitin C-terminal hydrolase (UCH)-like or ubiquitin specific protease (USP)-like domain is predicted to be catalytically inactive because it lacks the active site catalytic triad characteristic of thiol proteases, with residues at the equivalent structural positions that are incompatible with catalysis, and it cannot bind ubiquitin. It functions as a structural scaffold for intra- and intermolecular interactions in the complex.
messages: Cytoplasm
messages: Forms a heterotrimer with an asymmetric homodimer of the regulatory subunit PAN3 to form the poly(A)-nuclease (PAN) deadenylation complex.
messages: Positively regulated by the regulatory subunit PAN3.
messages: The linker, or PAN3 interaction domain (PID), between the WD40 repeats and the pseudo-UCH domain mediates interaction with PAN3.

214684:CNL03760
gene id: 214684:CNL03760
uniprot id: P0CP32
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleotide-sugar transporter family. SLC35B subfamily.
messages: Endoplasmic reticulum membrane
messages: May be involved in specific transport of UDP-Gal from the cytosol to the Golgi lumen. Involved in the maintenance of optimal conditions for the folding of secretory pathway proteins in the endoplasmic reticulum (By similarity).
messages: There are two genes coding for HUT1 in strain JEC21, due to a translocation and segmental duplication on chromosomes 8 and 12.

214684:CNE01460
gene id: 214684:CNE01460
uniprot id: Q5KH31
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DP1 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

214684:CNF00260
gene id: 214684:CNF00260
uniprot id: P0CM96
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associated with the spliceosome.
messages: Belongs to the CWC22 family.
messages: Cytoplasm
messages: Involved in pre-mRNA splicing.
messages: Nucleus

214684:CNL03900
gene id: 214684:CNL03900
uniprot id: Q5K8Z9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SRP68 family.
messages: Component of the signal recognition particle (SRP) complex, a ribonucleoprotein complex that mediates the cotranslational targeting of secretory and membrane proteins to the endoplasmic reticulum (ER). The SRP complex interacts with the signal sequence in nascent secretory and membrane proteins and directs them to the membrane of the ER.
messages: Cytoplasm
messages: nucleolus

214684:CNE04400
gene id: 214684:CNE04400
uniprot id: Q5KG95
names: Similarity
messages: Belongs to the cyclin family.

214684:CNJ02590
gene id: 214684:CNJ02590
uniprot id: Q5KA87
names: Subcellular Location Annotation
messages: Membrane

214684:CNI01670
gene id: 214684:CNI01670
uniprot id: Q5KBR4
names: Similarity
messages: Belongs to the peptidase A1 family.

214684:CNI03050
gene id: 214684:CNI03050
uniprot id: Q5KBC2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone H1/H5 family.
messages: Nucleus

214684:CNG03920
gene id: 214684:CNG03920
uniprot id: Q5KDH9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EROs family.
messages: Endoplasmic reticulum membrane
messages: May function both as a monomer and a homodimer.

214684:CNI01460
gene id: 214684:CNI01460
uniprot id: Q5KBT6
names: Subunit
messages: Associated with the spliceosome.

214684:CNG01210
gene id: 214684:CNG01210
uniprot id: Q5KEA3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UTP25 family.
messages: Component of the ribosomal small subunit (SSU) processome composed of at least 40 protein subunits and snoRNA U3.
messages: DEAD-box RNA helicase-like protein required for pre-18S rRNA processing, specifically at sites A0, A1, and A2.
messages: nucleolus

214684:CNI02370
gene id: 214684:CNI02370
uniprot id: Q9HFU4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mannose-6-phosphate isomerase type 1 family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Involved in the synthesis of the GDP-mannose and dolichol-phosphate-mannose required for a number of critical mannosyl transfer reactions.

214684:CNM02140
gene id: 214684:CNM02140
uniprot id: Q5K7K2
names: Similarity
messages: Belongs to the HARBI1 family.

214684:CNG03010
gene id: 214684:CNG03010
uniprot id: Q5KDR9
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the myo-inositol oxygenase family.
messages: Binds 2 iron ions per subunit.
messages: Cytoplasm

214684:CNF04540
gene id: 214684:CNF04540
uniprot id: P0CO84
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-3 subunit F family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex.
messages: Cytoplasm

214684:CNG03070
gene id: 214684:CNG03070
uniprot id: Q5KDR3
names: Similarity
names: Subunit
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
messages: Homotetramer. Residues from neighboring subunits contribute catalytic and substrate-binding residues to each active site.

214684:CNB02790
gene id: 214684:CNB02790
uniprot id: Q5KM64
names: Similarity
messages: Belongs to the glycosyl hydrolase 37 family.

214684:CNB02210
gene id: 214684:CNB02210
uniprot id: Q5KMC1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the actin family.
messages: Nucleus
messages: Probably involved in transcription regulation via its interaction with the INO80 complex, a chromatin remodeling complex.

214684:CNA05500
gene id: 214684:CNA05500
uniprot id: Q5KNS2
names: Similarity
messages: Belongs to the GTP cyclohydrolase II family.

214684:CNC04120
gene id: 214684:CNC04120
uniprot id: P0CO48
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aromatic-ring hydroxylase family. KMO subfamily.
messages: Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid.
messages: Mitochondrion outer membrane

214684:CNN00980
gene id: 214684:CNN00980
uniprot id: Q5K761
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

214684:CNE05120
gene id: 214684:CNE05120
uniprot id: Q5KG24
names: Similarity
messages: Belongs to the archaeal Rpo3/eukaryotic RPB3 RNA polymerase subunit family.

214684:CNF01540
gene id: 214684:CNF01540
uniprot id: Q5KFJ4
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.

214684:CND02790
gene id: 214684:CND02790
uniprot id: Q5KIJ0
names: Similarity
messages: Belongs to the universal ribosomal protein uS15 family.

214684:CNH03300
gene id: 214684:CNH03300
uniprot id: Q5KD50
names: Similarity
names: Subunit
messages: Belongs to the WD repeat coronin family.
messages: Homotrimer.

214684:CNH01860
gene id: 214684:CNH01860
uniprot id: Q5KCQ2
names: Subcellular Location Annotation
messages: Nucleus

214684:CNJ00360
gene id: 214684:CNJ00360
uniprot id: Q5KAV2
names: Subcellular Location Annotation
messages: Membrane

214684:CNE03280
gene id: 214684:CNE03280
uniprot id: Q5KGK6
names: Similarity
messages: Belongs to the epsin family.

214684:CNA00770
gene id: 214684:CNA00770
uniprot id: Q5KQ19
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

214684:CNF03550
gene id: 214684:CNF03550
uniprot id: P0CR58
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sorting nexin family.
messages: Cytoplasm
messages: Membrane
messages: Required for vacuolar protein sorting.
messages: The PX domain binds phosphatidylinositol 3-phosphate which is necessary for peripheral membrane localization.

214684:CNG00140
gene id: 214684:CNG00140
uniprot id: Q5KEK9
names: Similarity
messages: Belongs to the Rab GDI family.

214684:CNJ00850
gene id: 214684:CNJ00850
uniprot id: Q5KAQ7
names: Cofactor
names: Similarity
messages: Belongs to the eukaryotic GSH synthase family.
messages: Binds 1 Mg(2+) ion per subunit.

214684:CNJ01740
gene id: 214684:CNJ01740
uniprot id: Q5KAG9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DDOST 48 kDa subunit family.
messages: Component of the oligosaccharyltransferase (OST) complex.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER).

214684:CND02770
gene id: 214684:CND02770
uniprot id: Q5KIJ2
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

214684:CND01320
gene id: 214684:CND01320
uniprot id: Q5KIY3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NADPH--cytochrome P450 reductase family.
messages: Binds 1 FAD per monomer.
messages: Binds 1 FMN per monomer.
messages: Cell membrane
messages: Endoplasmic reticulum membrane
messages: In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
messages: In the N-terminal section; belongs to the flavodoxin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mitochondrion outer membrane
messages: This enzyme is required for electron transfer from NADP to cytochrome P450 in microsomes. It can also provide electron transfer to heme oxygenase and cytochrome B5. Involved in ergosterol biosynthesis.

214684:CNA06930
gene id: 214684:CNA06930
uniprot id: Q5KNC9
names: Similarity
messages: Belongs to the phosducin family.

214684:CNL05190
gene id: 214684:CNL05190
uniprot id: Q5K8L9
names: Similarity
messages: Belongs to the SNF2/RAD54 helicase family.

214684:CNC02050
gene id: 214684:CNC02050
uniprot id: Q5KKR9
names: Function
names: Similarity
messages: Belongs to the TVP38/TMEM64 family.
messages: Golgi membrane protein involved in vesicular trafficking and spindle migration.

214684:CNI02750
gene id: 214684:CNI02750
uniprot id: P0CN40
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eIF-2B alpha/beta/delta subunits family. MtnA subfamily.
messages: Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).
messages: Cytoplasm
messages: Nucleus

214684:CNC06720
gene id: 214684:CNC06720
uniprot id: Q5KJF5
names: Similarity
messages: Belongs to the TTI2 family.

214684:CNC04990
gene id: 214684:CNC04990
uniprot id: P0CQ12
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1B family.
messages: Cytoplasm
messages: Non-catalytic component of the proteasome, a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity (By similarity).
messages: Nucleus
messages: The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits. The 20S proteasome core is composed of 28 subunits that are arranged in four stacked rings, resulting in a barrel-shaped structure. The two end rings are each formed by seven alpha subunits, and the two central rings are each formed by seven beta subunits. The catalytic chamber with the active sites is on the inside of the barrel (By similarity).

214684:CNF03160
gene id: 214684:CNF03160
uniprot id: P0CN74
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
messages: Cytoplasm
messages: Homotetramer.

214684:CNG04660
gene id: 214684:CNG04660
uniprot id: Q5KDB2
names: Subcellular Location Annotation
messages: Membrane

214684:CNA01600
gene id: 214684:CNA01600
uniprot id: Q5KPT5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.
messages: cytoskeleton

214684:CNB04730
gene id: 214684:CNB04730
uniprot id: Q5KLM6
names: Similarity
messages: Belongs to the universal ribosomal protein uS4 family.

214684:CNA03520
gene id: 214684:CNA03520
uniprot id: Q5KPA5
names: Similarity
messages: Belongs to the AAR2 family.

214684:CNA02690
gene id: 214684:CNA02690
uniprot id: Q5KPI4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the V-ATPase proteolipid subunit family.
messages: Membrane
messages: Proton-conducting pore forming of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments.
messages: V-ATPase is a heteromultimeric enzyme composed of a peripheral catalytic V1 complex (components A to H) attached to an integral membrane V0 proton pore complex (components: a, c, c', c'', d, e, f and VOA1). The decameric c-ring forms the proton-conducting pore, and is composed of eight proteolipid subunits c, one subunit c' and one subunit c''.
messages: Vacuole membrane

214684:CNK02680
gene id: 214684:CNK02680
uniprot id: Q5K9A0
names: Similarity
messages: Belongs to the peptidase M24B family.

214684:CNN01070
gene id: 214684:CNN01070
uniprot id: Q5K752
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CSC1 (TC 1.A.17) family.
messages: Membrane

214684:CNC04690
gene id: 214684:CNC04690
uniprot id: Q5KK08
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

214684:CND04250
gene id: 214684:CND04250
uniprot id: Q5KI46
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

214684:CND00600
gene id: 214684:CND00600
uniprot id: Q5KJ56
names: Similarity
messages: Belongs to the peptidase S10 family.

214684:CNE04100
gene id: 214684:CNE04100
uniprot id: Q5KGC6
names: Similarity
messages: Belongs to the cyclin family.

214684:CNA04550
gene id: 214684:CNA04550
uniprot id: Q5KP16
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DAD/OST2 family.
messages: Component of the oligosaccharyltransferase (OST) complex.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All subunits are required for a maximal enzyme activity.

214684:CNA00740
gene id: 214684:CNA00740
uniprot id: Q5KQ22
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

214684:CNF04480
gene id: 214684:CNF04480
uniprot id: Q5KES1
names: Subcellular Location Annotation
messages: Membrane

214684:CNK03170
gene id: 214684:CNK03170
uniprot id: Q5K952
names: Function
names: Similarity
messages: Belongs to the transaldolase family. Type 1 subfamily.
messages: Catalyzes the rate-limiting step of the non-oxidative phase in the pentose phosphate pathway. Catalyzes the reversible conversion of sedheptulose-7-phosphate and D-glyceraldehyde 3-phosphate into erythrose-4-phosphate and beta-D-fructose 6-phosphate.

214684:CNF00460
gene id: 214684:CNF00460
uniprot id: Q5KFV2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

214684:CNA06290
gene id: 214684:CNA06290
uniprot id: Q5KNJ3
names: Similarity
messages: In the C-terminal section; belongs to the TrpB family.
messages: In the N-terminal section; belongs to the TrpA family.

214684:CNH01340
gene id: 214684:CNH01340
uniprot id: Q5KCK5
names: Similarity
messages: Belongs to the RRP15 family.

214684:CNJ01140
gene id: 214684:CNJ01140
uniprot id: Q5KAM8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mL41 family.
messages: Mitochondrion

214684:CNI02930
gene id: 214684:CNI02930
uniprot id: Q5KBD4
names: Similarity
messages: Belongs to the GHMP kinase family. Homoserine kinase subfamily.

214684:CNK01030
gene id: 214684:CNK01030
uniprot id: Q5K9R5
names: Function
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).

214684:CNI01880
gene id: 214684:CNI01880
uniprot id: P0CQ86
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent RNA helicase associated with the nuclear pore complex and essential for mRNA export from the nucleus. May participate in a terminal step of mRNA export through the removal of proteins that accompany mRNA through the nucleopore complex. May also be involved in early transcription (By similarity).
messages: Associates with the nuclear pore complex.
messages: Belongs to the DEAD box helicase family. DDX19/DBP5 subfamily.
messages: Cytoplasm
messages: Nucleus membrane
messages: The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.
messages: nuclear pore complex

214684:CND02280
gene id: 214684:CND02280
uniprot id: Q5KIP0
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

214684:CNJ02140
gene id: 214684:CNJ02140
uniprot id: Q5KAD0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetate uptake transporter (AceTr) (TC 2.A.96) family.
messages: Membrane

214684:CND03940
gene id: 214684:CND03940
uniprot id: Q5KI75
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the COPG family.
messages: COPI-coated vesicle membrane
messages: Cytoplasm
messages: Golgi apparatus membrane
messages: Membrane
messages: Oligomeric complex.
messages: The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.

214684:CNA00720
gene id: 214684:CNA00720
uniprot id: P0CO90
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family. NUBP2/CFD1 subfamily.
messages: Binds 4 [4Fe-4S] clusters per heterotetramer. Contains two stable clusters in the N-termini of NBP35 and two labile, bridging clusters between subunits of the NBP35-CFD1 heterotetramer.
messages: Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery. Required for maturation of extramitochondrial Fe-S proteins. The NBP35-CFD1 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins.
messages: Cytoplasm
messages: Heterotetramer of 2 NBP35 and 2 CFD1 chains.

214684:CNB05140
gene id: 214684:CNB05140
uniprot id: Q5KLI4
names: Similarity
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the N-terminal section; belongs to the AAA ATPase family.

214684:CNB00860
gene id: 214684:CNB00860
uniprot id: Q5KMQ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sphingosine N-acyltransferase family.
messages: Membrane

214684:CNA05580
gene id: 214684:CNA05580
uniprot id: Q5KNR5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I LYR family.
messages: Mitochondrion inner membrane

214684:CNJ00210
gene id: 214684:CNJ00210
uniprot id: Q5KAW7
names: Function
messages: Required for N-linked oligosaccharide assembly. Has a role in the last step of the synthesis of the Man(5)GlcNAc(2)-PP-dolichol core oligosaccharide on the cytoplasmic face of the endoplasmic reticulum.

214684:CNA05390
gene id: 214684:CNA05390
uniprot id: Q5KNT3
uniprot id: Q5KNT4
names: Similarity
messages: Belongs to the protein kinase superfamily.
messages: Belongs to the protein kinase superfamily. CK1 Ser/Thr protein kinase family. Casein kinase I subfamily.

214684:CNF00770
gene id: 214684:CNF00770
uniprot id: Q5KFS1
names: Similarity
names: Subunit
messages: Belongs to the ubiquitin-activating E1 family.
messages: Heterodimer.

214684:CNJ02470
gene id: 214684:CNJ02470
uniprot id: P0CP50
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the protein kinase superfamily. PAN3 family.
messages: Contains a pseudokinase domain. The protein kinase domain is predicted to be catalytically inactive because some of the residues important for catalytic activity are substituted and it lacks the equivalent of the binding site for a peptide substrate. However, it has retained an ATP-binding site and ATP-binding is required for mRNA degradation, stimulating the activity of the PAN2 nuclease in vitro. The nucleotide-binding site is juxtaposed to the RNase active site of PAN2 in the complex and may actually bind nucleosides of a poly(A) RNA rather than ATP, feeding the poly(A)-tail to the active site of the deadenylase and thus increasing the efficiency with which this distributive enzyme degrades oligo(A) RNAs.
messages: Cytoplasm
messages: Homodimer. Forms a heterotrimer with a catalytic subunit PAN2 to form the poly(A)-nuclease (PAN) deadenylation complex. Interacts (via PAM-2 motif) with poly(A)-binding protein PAB1 (via PABC domain), conferring substrate specificity of the enzyme complex.
messages: Regulatory subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein PAB1. PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenylation-dependent mRNA decaping and subsequent 5'-3' exonucleolytic degradation by XRN1. May also be involved in post-transcriptional maturation of mRNA poly(A) tails. PAN3 acts as a positive regulator for PAN activity, recruiting the catalytic subunit PAN2 to mRNA via its interaction with RNA and with PAB1.
messages: The N-terminal zinc finger binds to poly(A) RNA.
messages: The pseudokinase domain, the coiled-coil (CC), and C-terminal knob domain (CK) form a structural unit (PKC) that forms an extensive high-affinity interaction surface for PAN2.

214684:CNH02680
gene id: 214684:CNH02680
uniprot id: Q5KCY7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SCO1/2 family.
messages: Mitochondrion inner membrane

214684:CNA02130
gene id: 214684:CNA02130
uniprot id: Q5KPN5
names: Similarity
messages: Belongs to the SPT2 family.

214684:CNE03050
gene id: 214684:CNE03050
uniprot id: Q5KGM9
names: Similarity
messages: Belongs to the PPP phosphatase family.

214684:CND02340
gene id: 214684:CND02340
uniprot id: Q5KIN4
names: Similarity
names: Subunit
messages: Belongs to the allantoicase family.
messages: Homodimer.

214684:CNA02780
gene id: 214684:CNA02780
uniprot id: Q5KPH5
names: Similarity
messages: Belongs to the peptidase M28 family.

214684:CNF01080
gene id: 214684:CNF01080
uniprot id: Q5KFP2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1B family.
messages: Component of the proteasome complex.
messages: Component of the proteasome, a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.
messages: Cytoplasm
messages: Nucleus

214684:CNF01260
gene id: 214684:CNF01260
uniprot id: Q5KFM3
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

214684:CNE00480
gene id: 214684:CNE00480
uniprot id: Q5KHC9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CNEP1R1 family.
messages: Cytoplasm
messages: Membrane
messages: Nucleus membrane

214684:CNB01310
gene id: 214684:CNB01310
uniprot id: Q5KML2
names: Similarity
messages: Belongs to the complex I 75 kDa subunit family.

214684:CNK00680
gene id: 214684:CNK00680
uniprot id: Q5K9V0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sterol desaturase family. SCS7 subfamily.
messages: Binds 2 Zn(2+) ions per subunit that likely form a catalytic dimetal center.
messages: Ceramide hydroxylase involved in the hydroxylation of sphingolipid-associated very long chain fatty acids. Postulated to hydroxylate the very long chain fatty acid of dihydroceramides and phytoceramides at C-2.
messages: Endoplasmic reticulum membrane
messages: Membrane

214684:CNB05160
gene id: 214684:CNB05160
uniprot id: Q5KLI2
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family.
messages: Mitochondrial transcription factor that confers selective promoter recognition on the core subunit of the yeast mitochondrial RNA polymerase. Interacts with DNA in a non-specific manner.

214684:CNN00570
gene id: 214684:CNN00570
uniprot id: Q5K7A1
names: Subcellular Location Annotation
messages: Membrane

214684:CNC04240
gene id: 214684:CNC04240
uniprot id: Q5KK51
names: Subcellular Location Annotation
messages: Membrane

214684:CNF01790
gene id: 214684:CNF01790
uniprot id: Q5KFG9
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL33 family.

214684:CNG02220
gene id: 214684:CNG02220
uniprot id: Q5KE00
uniprot id: Q5KE01
names: Similarity
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Monomer.

214684:CNC02580
gene id: 214684:CNC02580
uniprot id: P0CR88
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Tim17/Tim22/Tim23 family.
messages: Component of the TIM22 complex, whose core is composed of TIM22 and TIM54, associated with the 70 kDa heterohexamer composed of TIM9 and TIM10 (or TIM8 and TIM13).
messages: Essential core component of the TIM22 complex, a complex that mediates the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane. In the TIM22 complex, it constitutes the voltage-activated and signal-gated channel. Forms a twin-pore translocase that uses the membrane potential as external driving force in 2 voltage-dependent steps (By similarity).
messages: Mitochondrion inner membrane

214684:CNN01670
gene id: 214684:CNN01670
uniprot id: Q5K6Z7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bZIP family.
messages: Nucleus

214684:CNJ01600
gene id: 214684:CNJ01600
uniprot id: Q5KAI1
names: Subcellular Location Annotation
messages: Membrane

214684:CNA03100
gene id: 214684:CNA03100
uniprot id: Q5KPE3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the XPG/RAD2 endonuclease family. XPG subfamily.
messages: Nucleus

214684:CNA02420
gene id: 214684:CNA02420
uniprot id: Q5KPL0
names: Function
names: Similarity
messages: Belongs to the SEC15 family.
messages: Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.

214684:CNB01330
gene id: 214684:CNB01330
uniprot id: Q5KML0
names: Subcellular Location Annotation
messages: Membrane

214684:CNJ00130
gene id: 214684:CNJ00130
uniprot id: Q5KAX5
names: Function
names: Similarity
messages: Acts as a regulatory subunit of the 26 proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins.
messages: Belongs to the proteasome subunit S2 family.

214684:CNG01190
gene id: 214684:CNG01190
uniprot id: Q5KEA5
names: Similarity
messages: Belongs to the LipB family.

214684:CNI02510
gene id: 214684:CNI02510
uniprot id: Q5KBH5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CBF/MAK21 family.
messages: Required for synthesis of 60S ribosomal subunits and the transport of pre-ribosomes from the nucleoplasm to the cytoplasm.
messages: nucleolus

214684:CNL04520
gene id: 214684:CNL04520
uniprot id: Q5K8T9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.
messages: cytoskeleton

214684:CNK02460
gene id: 214684:CNK02460
uniprot id: Q5K9C2
names: Similarity
messages: Belongs to the amino acid/polyamine transporter 2 family.

214684:CNB03530
gene id: 214684:CNB03530
uniprot id: Q5KLZ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the actin-binding proteins ADF family. Twinfilin subfamily.
messages: cytoskeleton

214684:CNJ01190
gene id: 214684:CNJ01190
uniprot id: Q5KAM3
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

214684:CNE02460
gene id: 214684:CNE02460
uniprot id: Q5KGT0
names: Subcellular Location Annotation
messages: Membrane

214684:CND02430
gene id: 214684:CND02430
uniprot id: Q5KIM5
names: Subcellular Location Annotation
messages: Membrane

214684:CND01190
gene id: 214684:CND01190
uniprot id: P0CS60
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XPG/RAD2 endonuclease family. FEN1 subfamily.
messages: Binds 2 magnesium ions per subunit. They probably participate in the reaction catalyzed by the enzyme. May bind an additional third magnesium ion after substrate binding.
messages: Interacts with PCNA. Three molecules of FEN1 bind to one PCNA trimer with each molecule binding to one PCNA monomer. PCNA stimulates the nuclease activity without altering cleavage specificity.
messages: Mitochondrion
messages: Phosphorylated. Phosphorylation upon DNA damage induces relocalization to the nuclear plasma.
messages: Structure-specific nuclease with 5'-flap endonuclease and 5'-3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site-terminated flap. Acts as a genome stabilization factor that prevents flaps from equilibrating into structures that lead to duplications and deletions. Also possesses 5'-3' exonuclease activity on nicked or gapped double-stranded DNA, and exhibits RNase H activity. Also involved in replication and repair of rDNA and in repairing mitochondrial DNA.
messages: nucleolus
messages: nucleoplasm

214684:CNI00140
gene id: 214684:CNI00140
uniprot id: Q5KC59
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEC62 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

214684:CNN02220
gene id: 214684:CNN02220
uniprot id: Q5K6U7
names: Similarity
messages: Belongs to the peptidase S33 family.

214684:CNA06890
gene id: 214684:CNA06890
uniprot id: P0CR50
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associated with the spliceosome.
messages: Belongs to the SLT11 family.
messages: Involved in pre-mRNA splicing. Facilitates the cooperative formation of U2/U6 helix II in association with stem II in the spliceosome. Binds to RNA (By similarity).
messages: Nucleus

214684:CNE00560
gene id: 214684:CNE00560
uniprot id: Q5KHC0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DHBP synthase family.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Homodimer.

214684:CNE02500
gene id: 214684:CNE02500
uniprot id: P0CQ36
names: Similarity
messages: In the C-terminal section; belongs to the AIR carboxylase family. Class I subfamily.

214684:CNJ02330
gene id: 214684:CNJ02330
uniprot id: Q5KAB2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GOLPH3/VPS74 family.
messages: Membrane

214684:CNH03170
gene id: 214684:CNH03170
uniprot id: Q5KD36
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the myo-inositol oxygenase family.
messages: Binds 2 iron ions per subunit.
messages: Cytoplasm

214684:CNI02110
gene id: 214684:CNI02110
uniprot id: P0CN62
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EXO84 family.
messages: Component of the exocyst complex.
messages: Involved in the secretory pathway as part of the exocyst complex which tethers secretory vesicles to the sites of exocytosis. Plays a role in both the assembly of the exocyst and the polarization of this complex to specific sites of the plasma membrane for exocytosis. Also involved in assembly of the spliceosome (By similarity).
messages: secretory vesicle

214684:CNF02390
gene id: 214684:CNF02390
uniprot id: Q5KFA8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the oligopeptide OPT transporter family.
messages: Membrane

214684:CNL05940
gene id: 214684:CNL05940
uniprot id: Q5K8F0
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

214684:CNC02240
gene id: 214684:CNC02240
uniprot id: Q5KKQ1
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family. UEV subfamily.

214684:CNF01850
gene id: 214684:CNF01850
uniprot id: Q5KFG3
names: Similarity
messages: Belongs to the SIKE family.

214684:CNH00790
gene id: 214684:CNH00790
uniprot id: Q5KCF1
names: Similarity
messages: Belongs to the glycosyl hydrolase 9 (cellulase E) family.

214684:CNC01510
gene id: 214684:CNC01510
uniprot id: Q5KKX5
names: Similarity
messages: Belongs to the MAD2 family.

214684:CND04430
gene id: 214684:CND04430
uniprot id: Q5KI28
names: Similarity
messages: Belongs to the UQCRB/QCR7 family.

214684:CNK00590
gene id: 214684:CNK00590
uniprot id: Q5K9V8
names: Subcellular Location Annotation
messages: Nucleus

214684:CNE00590
gene id: 214684:CNE00590
uniprot id: P0CQ78
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: ATP-dependent RNA helicase required for 60S ribosomal subunit synthesis. Involved in efficient pre-rRNA processing, predominantly at site A3, which is necessary for the normal formation of 25S and 5.8S rRNAs (By similarity).
messages: Belongs to the DEAD box helicase family. DDX5/DBP2 subfamily.
messages: The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.
messages: nucleolus

214684:CNG02100
gene id: 214684:CNG02100
uniprot id: P0CM44
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BRO1 family.
messages: Cytoplasm
messages: Endosome
messages: Involved in concentration and sorting of cargo proteins of the multivesicular body (MVB) for incorporation into intralumenal vesicles.

214684:CNJ03320
gene id: 214684:CNJ03320
uniprot id: Q5KA24
names: Similarity
messages: Belongs to the peptidase S10 family.

214684:CNH02900
gene id: 214684:CNH02900
uniprot id: Q5KD09
names: Similarity
messages: Belongs to the glycosyl hydrolase 5 (cellulase A) family.

214684:CNG01380
gene id: 214684:CNG01380
uniprot id: Q5KE85
names: Subcellular Location Annotation
messages: Nucleus

214684:CNC04130
gene id: 214684:CNC04130
uniprot id: Q5KK62
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
messages: Binds 1 FMN per subunit.
messages: Mitochondrion inner membrane

214684:CNE05290
gene id: 214684:CNE05290
uniprot id: Q5KG08
names: Similarity
messages: Belongs to the D-glutamate cyclase family.

214684:CNI02350
gene id: 214684:CNI02350
uniprot id: Q5KBJ2
names: Similarity
messages: Belongs to the NAD kinase family.

214684:CNM02550
gene id: 214684:CNM02550
uniprot id: Q5K7G2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine-cytosine permease (2.A.39) family.
messages: Membrane

214684:CNA02180
gene id: 214684:CNA02180
uniprot id: Q5KPN0
names: Similarity
messages: Belongs to the RMD1/sif2 family.

214684:CNE01660
gene id: 214684:CNE01660
uniprot id: Q5KH09
names: Similarity
messages: Belongs to the methyltransferase superfamily. Trimethylguanosine synthase family.

214684:CNF01060
gene id: 214684:CNF01060
uniprot id: Q5KFP4
names: Subcellular Location Annotation
messages: Membrane

214684:CNH01090
gene id: 214684:CNH01090
uniprot id: Q5KCI0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TBP family.
messages: Nucleus

214684:CNA01840
gene id: 214684:CNA01840
uniprot id: Q5KPR2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the C1D family.
messages: Nucleus
messages: Required for exosome-dependent processing of pre-rRNA and small nucleolar RNA (snRNA) precursors. Involved in processing of 35S pre-rRNA at the A0, A1 and A2 sites.

214684:CNK00830
gene id: 214684:CNK00830
uniprot id: Q5K9T5
names: Subcellular Location Annotation
names: Subunit
messages: Associated with the spliceosome.
messages: Nucleus

214684:CND03500
gene id: 214684:CND03500
uniprot id: Q5KIC1
names: Similarity
messages: Belongs to the arginase family.

214684:CNC00500
gene id: 214684:CNC00500
uniprot id: Q5KL74
names: Similarity
messages: Belongs to the REXO1/REXO3 family.

214684:CND01890
gene id: 214684:CND01890
uniprot id: Q5KIS8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NOSIP family.
messages: Nucleus

214684:CNM00240
gene id: 214684:CNM00240
uniprot id: P0CP14
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
messages: Mitochondrion outer membrane
messages: Monomer. Component of the 2-(3-amino-3-carboxypropyl)histidine synthase complex composed of DPH1, DPH2, DPH3 and a NADH-dependent reductase, predominantly CBR1.
messages: NADH-dependent reductase for DPH3 and cytochrome b5. Required for the first step of diphthamide biosynthesis, a post-translational modification of histidine which occurs in elongation factor 2. DPH1 and DPH2 transfer a 3-amino-3-carboxypropyl (ACP) group from S-adenosyl-L-methionine (SAM) to a histidine residue, the reaction is assisted by a reduction system comprising DPH3 and a NADH-dependent reductase, predominantly CBR1. By reducing DPH3, also involved in the formation of the tRNA wobble base modification mcm5s 2U (5-methoxycarbonylmethyl-2-thiouridine), mediated by the elongator complex. The cytochrome b5/NADH cytochrome b5 reductase electron transfer system supports the catalytic activity of several sterol biosynthetic enzymes.

214684:CNA04950
gene id: 214684:CNA04950
uniprot id: Q5KNX7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NOP53 family.
messages: May play a role in ribosome biogenesis.
messages: nucleolus
messages: nucleoplasm

214684:CNI01770
gene id: 214684:CNI01770
uniprot id: Q5KBQ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the archaeal Rpo6/eukaryotic RPB6 RNA polymerase subunit family.
messages: Nucleus

214684:CNE03380
gene id: 214684:CNE03380
uniprot id: Q5KGJ6
names: Function
names: Similarity
messages: Belongs to the APS kinase family.
messages: Catalyzes the synthesis of activated sulfate.

214684:CNA01230
gene id: 214684:CNA01230
uniprot id: Q5KPX3
names: Similarity
messages: Belongs to the ubiquitin-activating E1 family.

214684:CND03800
gene id: 214684:CND03800
uniprot id: Q5KI89
names: Similarity
messages: Belongs to the MYG1 family.

214684:CNM00930
gene id: 214684:CNM00930
uniprot id: P0CS76
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.
messages: Component of the SRB8-11 complex, a regulatory module of the Mediator complex.
messages: Component of the SRB8-11 complex. The SRB8-11 complex is a regulatory module of the Mediator complex which is itself involved in regulation of basal and activated RNA polymerase II-dependent transcription. The SRB8-11 complex may be involved in the transcriptional repression of a subset of genes regulated by Mediator. It may inhibit the association of the Mediator complex with RNA polymerase II to form the holoenzyme complex. The SRB8-11 complex phosphorylates the C-terminal domain (CTD) of the largest subunit of RNA polymerase II (By similarity).
messages: Nucleus

214684:CNE02360
gene id: 214684:CNE02360
uniprot id: Q5KGU0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the casein kinase 2 subunit beta family.
messages: Regulatory subunit of casein kinase II/CK2 (By similarity). As part of the kinase complex regulates the basal catalytic activity of the alpha subunit a constitutively active serine/threonine-protein kinase that phosphorylates a large number of substrates containing acidic residues C-terminal to the phosphorylated serine or threonine.
messages: Regulatory subunit of casein kinase II/CK2. As part of the kinase complex regulates the basal catalytic activity of the alpha subunit a constitutively active serine/threonine-protein kinase that phosphorylates a large number of substrates containing acidic residues C-terminal to the phosphorylated serine or threonine.
messages: Tetramer of two alpha and two beta subunits.

214684:CNE03350
gene id: 214684:CNE03350
uniprot id: P0CM48
names: Function
names: Similarity
messages: Belongs to the palC family.
messages: Required for the proteolytic cleavage of the transcription factor RIM101 in response to alkaline ambient pH.

214684:CNA04660
gene id: 214684:CNA04660
uniprot id: Q5KP05
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

214684:CNF02520
gene id: 214684:CNF02520
uniprot id: Q5KF97
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Alax-L subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm
messages: Mitochondrion
messages: Monomer.

214684:CNG03160
gene id: 214684:CNG03160
uniprot id: Q5KDQ4
names: Similarity
messages: Belongs to the universal ribosomal protein uL6 family.

214684:CNB04260
gene id: 214684:CNB04260
uniprot id: Q5KLS2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
messages: Catalyzes the synthesis of 5-aminolevulinate (ALA) from succinyl-CoA and glycine, the first and rate-limiting step in heme biosynthesis.
messages: Mitochondrion matrix

214684:CNI01830
gene id: 214684:CNI01830
uniprot id: Q5KBP8
names: Similarity
messages: Belongs to the CBF/MAK21 family.

214684:CNJ01110
gene id: 214684:CNJ01110
uniprot id: Q5KAN1
names: Similarity
messages: Belongs to the SAP18 family.

214684:CNB04960
gene id: 214684:CNB04960
uniprot id: Q5KLK2
names: Similarity
messages: Belongs to the proteasome subunit S11 family.

214684:CNC05900
gene id: 214684:CNC05900
uniprot id: Q5KJN5
names: Subcellular Location Annotation
messages: Nucleus

214684:CNE00880
gene id: 214684:CNE00880
uniprot id: Q5KH88
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nonaspanin (TM9SF) (TC 9.A.2) family.
messages: Membrane

214684:CNL03700
gene id: 214684:CNL03700
uniprot id: Q5K920
names: Similarity
messages: Belongs to the group II decarboxylase family.

214684:CNF03970
gene id: 214684:CNF03970
uniprot id: Q5KEW6
names: Cofactor
names: Similarity
messages: Belongs to the radical SAM superfamily. Biotin synthase family.
messages: Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

214684:CNG02520
gene id: 214684:CNG02520
uniprot id: Q5KDW9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chitin synthase family.
messages: Cell membrane
messages: Membrane
messages: Polymerizes chitin, a structural polymer of the cell wall and septum, by transferring the sugar moiety of UDP-GlcNAc to the non-reducing end of the growing chitin polymer.

214684:CNJ00860
gene id: 214684:CNJ00860
uniprot id: Q5KAQ6
names: Subcellular Location Annotation
messages: Nucleus

214684:CNA05850
gene id: 214684:CNA05850
uniprot id: P0CS32
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-3 subunit I family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex.
messages: Cytoplasm

214684:CNI03910
gene id: 214684:CNI03910
uniprot id: Q5KB36
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TVP38/TMEM64 family.
messages: Golgi membrane protein involved in vesicular trafficking and spindle migration.
messages: Membrane

214684:CNN01330
gene id: 214684:CNN01330
uniprot id: Q5K728
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome c oxidase VIIc family.
messages: Component of the cytochrome c oxidase (complex IV, CIV), a multisubunit enzyme composed of a catalytic core of 3 subunits and several supernumerary subunits. The complex exists as a monomer or a dimer and forms supercomplexes (SCs) in the inner mitochondrial membrane with ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII).
messages: Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)). The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
messages: Membrane
messages: Mitochondrion inner membrane

214684:CNE00350
gene id: 214684:CNE00350
uniprot id: Q5KHE5
names: Activity Regulation
names: Similarity
messages: Activated by threonine and tyrosine phosphorylation.
messages: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.

214684:CNI02850
gene id: 214684:CNI02850
uniprot id: P0CR00
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent rRNA helicase required for pre-ribosomal RNA processing. Involved in the maturation of the 35S-pre-rRNA and to its cleavage to mature 18S rRNA.
messages: Belongs to the DEAD box helicase family. DDX47/RRP3 subfamily.
messages: Interacts with the SSU processome.
messages: Nucleus
messages: The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.

214684:CND04080
gene id: 214684:CND04080
uniprot id: Q5KI63
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

214684:CNE03320
gene id: 214684:CNE03320
uniprot id: Q5KGK2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NOP5/NOP56 family.
messages: nucleolus

214684:CND02880
gene id: 214684:CND02880
uniprot id: P0CO44
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BBP/SF1 family.
messages: Necessary for the splicing of pre-mRNA. Has a role in the recognition of the branch site (5'-UACUAAC-3'), the pyrimidine tract and the 3'-splice site at the 3'-end of introns (By similarity).
messages: Nucleus

214684:CNE04510
gene id: 214684:CNE04510
uniprot id: Q5KG83
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

214684:CNM00800
gene id: 214684:CNM00800
uniprot id: Q5K7Z0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. YAT (TC 2.A.3.10) family.
messages: Membrane

214684:CNC02010
gene id: 214684:CNC02010
uniprot id: Q5KKS4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase PH family.
messages: Cytoplasm
messages: nucleolus

214684:CNC00510
gene id: 214684:CNC00510
uniprot id: Q5KL73
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Arginine methyltransferase involved in the assembly or stability of mitochondrial NADH:ubiquinone oxidoreductase complex (complex I).
messages: Belongs to the NDUFAF7 family.
messages: Mitochondrion

214684:CNI00130
gene id: 214684:CNI00130
uniprot id: Q5KC60
names: Subcellular Location Annotation
messages: Nucleus

214684:CNE04860
gene id: 214684:CNE04860
uniprot id: Q5KG50
names: Function
names: Similarity
messages: Belongs to the proline oxidase family.
messages: Converts proline to delta-1-pyrroline-5-carboxylate.

214684:CNC02130
gene id: 214684:CNC02130
uniprot id: Q5KKR2
names: Similarity
messages: Belongs to the sorting nexin family.

214684:CND01170
gene id: 214684:CND01170
uniprot id: Q5KIZ8
names: Similarity
messages: Belongs to the peptidase C12 family.

214684:CNB05030
gene id: 214684:CNB05030
uniprot id: Q5KLJ6
names: Similarity
messages: Belongs to the universal ribosomal protein uL24 family.

214684:CNM02430
gene id: 214684:CNM02430
uniprot id: Q5K7H4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the oxidase-dependent Fe transporter (OFeT) (TC 9.A.10.1) family.
messages: Membrane

214684:CND05800
gene id: 214684:CND05800
uniprot id: Q5KHP2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 4 family.
messages: Membrane

214684:CNA02910
gene id: 214684:CNA02910
uniprot id: Q5KPG2
names: Similarity
messages: Belongs to the peptidase M20A family.

214684:CNL04820
gene id: 214684:CNL04820
uniprot id: Q5K8Q9
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

214684:CNF04030
gene id: 214684:CNF04030
uniprot id: Q5KEW2
names: Subcellular Location Annotation
messages: Nucleus

214684:CNE00040
gene id: 214684:CNE00040
uniprot id: Q5KG11
names: Similarity
messages: Belongs to the enolase family.

214684:CNH01080
gene id: 214684:CNH01080
uniprot id: Q5KCH9
names: Similarity
messages: Belongs to the putative lipase ROG1 family.

214684:CNK00030
gene id: 214684:CNK00030
uniprot id: Q5KA08
names: Subcellular Location Annotation
messages: Membrane

214684:CNK01960
gene id: 214684:CNK01960
uniprot id: Q5K9H1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TCP-1 chaperonin family.
messages: Cytoplasm

214684:CNL04540
gene id: 214684:CNL04540
uniprot id: P0CP00
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
messages: Phosphorylation of the TEDS site (Ser-363) is required for the polarization of the actin cytoskeleton. Phosphorylation probably activates the myosin-I ATPase activity (By similarity).
messages: The myosin motor domain displays actin-stimulated ATPase activity and generates a mechanochemical force.
messages: The tail domain participates in molecular interactions that specify the role of the motor domain (By similarity). It is composed of several tail homology (TH) domains, namely a putative phospholipid-binding myosin tail domain (also named TH1), an Ala- and Pro-rich domain (TH2), followed by an SH3 domain and a C-terminal acidic domain (TH3).
messages: Type-I myosin implicated in the organization of the actin cytoskeleton. Required for proper actin cytoskeleton polarization. At the cell cortex, assembles in patch-like structures together with proteins from the actin-polymerizing machinery and promotes actin assembly. Functions as actin nucleation-promoting factor (NPF) for the Arp2/3 complex (By similarity).
messages: actin patch

214684:CNE04360
gene id: 214684:CNE04360
uniprot id: Q5KG99
names: Similarity
messages: Belongs to the thiolase-like superfamily. Fungal fatty acid synthetase subunit alpha family.

214684:CNB03940
gene id: 214684:CNB03940
uniprot id: Q5KLV4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELOF1 family.
messages: Nucleus
messages: Transcription elongation factor implicated in the maintenance of proper chromatin structure in actively transcribed regions.

214684:CND04480
gene id: 214684:CND04480
uniprot id: Q5KI23
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS24 family.

214684:CNF00890
gene id: 214684:CNF00890
uniprot id: Q5KFR0
names: Subcellular Location Annotation
messages: Cytoplasm

214684:CNF00670
gene id: 214684:CNF00670
uniprot id: Q5KFT0
names: Similarity
messages: Belongs to the universal ribosomal protein uS11 family.

214684:CNA00470
gene id: 214684:CNA00470
uniprot id: Q5KQ48
names: Similarity
messages: Belongs to the FBPase class 1 family.

214684:CNI01180
gene id: 214684:CNI01180
uniprot id: Q5KBW0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Non-catalytic subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments.
messages: V-ATPase is a heteromultimeric enzyme composed of a peripheral catalytic V1 complex attached to an integral membrane V0 proton pore complex.

214684:CND02300
gene id: 214684:CND02300
uniprot id: Q5KIN8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RRP8 family.
messages: S-adenosyl-L-methionine-dependent methyltransferase that specifically methylates the N(1) position of adenine in helix 25.1 in 25S rRNA. Required both for ribosomal 40S and 60S subunits biogenesis. Required for efficient pre-rRNA cleavage at site A2.
messages: nucleolus

214684:CNJ00560
gene id: 214684:CNJ00560
uniprot id: Q5KAT6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the oligopeptide OPT transporter family.
messages: Membrane

214684:CNG02740
gene id: 214684:CNG02740
uniprot id: Q5KDU6
names: Cofactor
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS27 family.
messages: Binds 1 zinc ion per subunit.

214684:CNK00460
gene id: 214684:CNK00460
uniprot id: Q5K9W6
names: Similarity
messages: Belongs to the SDO1/SBDS family.

214684:CNB00430
gene id: 214684:CNB00430
uniprot id: Q5KMU7
names: Subcellular Location Annotation
messages: Membrane

214684:CNJ00890
gene id: 214684:CNJ00890
uniprot id: Q5KAQ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SURF4 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

214684:CNB04080
gene id: 214684:CNB04080
uniprot id: P0CM00
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I LYR family. SDHAF3 subfamily.
messages: Interacts with the iron-sulfur protein subunit within the SDH catalytic dimer.
messages: Mitochondrion matrix
messages: Plays an essential role in the assembly of succinate dehydrogenase (SDH), an enzyme complex (also referred to as respiratory complex II) that is a component of both the tricarboxylic acid (TCA) cycle and the mitochondrial electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Promotes maturation of the iron-sulfur protein subunit of the SDH catalytic dimer, protecting it from the deleterious effects of oxidants. May act together with SDHAF1.

214684:CND05430
gene id: 214684:CND05430
uniprot id: Q5KHS8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DASH complex DUO1 family.
messages: Nucleus
messages: kinetochore

214684:CNJ02050
gene id: 214684:CNJ02050
uniprot id: Q5KAD8
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily. METL family.
messages: S-adenosyl-L-methionine-dependent methyltransferase.

214684:CNJ00330
gene id: 214684:CNJ00330
uniprot id: Q5KAV5
names: Subcellular Location Annotation
messages: Nucleus

214684:CNG03470
gene id: 214684:CNG03470
uniprot id: Q5KDM2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ARV1 family.
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mediator of sterol homeostasis involved in sterol uptake, trafficking and distribution into membranes.
messages: Membrane
messages: Regulates also the sphingolipid metabolism.

214684:CNN01910
gene id: 214684:CNN01910
uniprot id: Q5K6X0
names: Similarity
messages: Belongs to the universal ribosomal protein uS12 family.

214684:CNH00830
gene id: 214684:CNH00830
uniprot id: P0CR56
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associated with the spliceosome.
messages: Belongs to the SNW family.
messages: Involved in pre-mRNA splicing.
messages: Nucleus

214684:CNM00390
gene id: 214684:CNM00390
uniprot id: Q5K823
names: Similarity
messages: Belongs to the prokaryotic/mitochondrial release factor family.

214684:CNI00910
gene id: 214684:CNI00910
uniprot id: Q5KBY9
names: Similarity
messages: Belongs to the SELO family.

214684:CNJ00350
gene id: 214684:CNJ00350
uniprot id: Q5KAV3
names: Similarity
names: Subunit
messages: Belongs to the peptidase S9A family.
messages: Monomer.

214684:CNB01890
gene id: 214684:CNB01890
uniprot id: Q5KMF5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adaptor complexes medium subunit family.
messages: Cell membrane
messages: coated pit

214684:CND05790
gene id: 214684:CND05790
uniprot id: Q5KHP3
names: Similarity
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.

214684:CNG00300
gene id: 214684:CNG00300
uniprot id: Q5KEJ6
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules. The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain. The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel. uL10 forms part of the P stalk that participates in recruiting G proteins to the ribosome.

214684:CNN00770
gene id: 214684:CNN00770
uniprot id: Q5K782
names: Subcellular Location Annotation
messages: Membrane

214684:CNH03460
gene id: 214684:CNH03460
uniprot id: Q5KD66
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

214684:CNA06210
gene id: 214684:CNA06210
uniprot id: P0CR70
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SPT5 family.
messages: Component of the SPT4-SPT5 complex. Interacts with RNA polymerase II (By similarity).
messages: Nucleus
messages: The SPT4-SPT5 complex mediates both activation and inhibition of transcription elongation, and plays a role in pre-mRNA processing. This complex seems to be important for the stability of the RNA polymerase II elongation machinery on the chromatin template but not for the inherent ability of this machinery to translocate down the gene (By similarity).

214684:CNA01910
gene id: 214684:CNA01910
uniprot id: Q5KPQ5
names: Subcellular Location Annotation
messages: nuclear pore complex

214684:CNH03840
gene id: 214684:CNH03840
uniprot id: Q5K905
names: Domain
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.
messages: The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate.

214684:CND04200
gene id: 214684:CND04200
uniprot id: Q5KI51
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eS21 family.
messages: Component of the small ribosomal subunit.
messages: Cytoplasm
messages: Required for the processing of the 20S rRNA-precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits. Has a physiological role leading to 18S rRNA stability.

214684:CNI01530
gene id: 214684:CNI01530
uniprot id: P0CL90
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AATF family.
messages: nucleolus

214684:CNM01090
gene id: 214684:CNM01090
uniprot id: Q5K7W1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Catalyzes the exchange of ADP and ATP across the membrane.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Monomer.

214684:CNA00530
gene id: 214684:CNA00530
uniprot id: Q5KQ43
names: Similarity
messages: Belongs to the proteasome subunit S3 family.

214684:CNG04260
gene id: 214684:CNG04260
uniprot id: Q5KDE6
names: Similarity
messages: Belongs to the cullin family.

214684:CNJ00590
gene id: 214684:CNJ00590
uniprot id: Q5KAT3
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 3 family.
messages: Transfers the glycosyl residue from UDP-Glc to the non-reducing end of alpha-1,4-glucan.

214684:CNC01760
gene id: 214684:CNC01760
uniprot id: Q5KKV0
names: Function
names: Similarity
messages: Belongs to the tRNA-intron endonuclease family.
messages: Constitutes one of the two catalytic subunit of the tRNA-splicing endonuclease complex, a complex responsible for identification and cleavage of the splice sites in pre-tRNA. It cleaves pre-tRNA at the 5'- and 3'-splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3'-cyclic phosphate and 5'-OH termini. There are no conserved sequences at the splice sites, but the intron is invariably located at the same site in the gene, placing the splice sites an invariant distance from the constant structural features of the tRNA body.

214684:CNI03880
gene id: 214684:CNI03880
uniprot id: Q5KB39
names: Similarity
messages: Belongs to the peptidase C65 family.

214684:CNN01190
gene id: 214684:CNN01190
uniprot id: Q5K741
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TFB2 family.
messages: Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA.
messages: Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to TFIIK, in RNA transcription by RNA polymerase II. In NER, TFIIH acts by opening DNA around the lesion to allow the excision of the damaged oligonucleotide and its replacement by a new DNA fragment. In transcription, TFIIH has an essential role in transcription initiation. When the pre-initiation complex (PIC) has been established, TFIIH is required for promoter opening and promoter escape. Phosphorylation of the C-terminal tail (CTD) of the largest subunit of RNA polymerase II by the kinase module TFIIK controls the initiation of transcription.
messages: Nucleus

214684:CNA05510
gene id: 214684:CNA05510
uniprot id: Q5KNS1
names: Similarity
names: Subunit
messages: Belongs to the cAMP-dependent kinase regulatory chain family.
messages: Tetramer, composed of 2 regulatory (R) and 2 catalytic (C) subunits. In the presence of cAMP it dissociates into 2 active monomeric C subunits and an R dimer.

214684:CNB00190
gene id: 214684:CNB00190
uniprot id: Q5KMX3
names: Function
names: Similarity
messages: Belongs to the ACC deaminase/D-cysteine desulfhydrase family.
messages: Catalyzes a cyclopropane ring-opening reaction, the irreversible conversion of 1-aminocyclopropane-1-carboxylate (ACC) to ammonia and alpha-ketobutyrate.

214684:CNF03700
gene id: 214684:CNF03700
uniprot id: P0CN16
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DP1 family.
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Oligomer.
messages: Required to generate and maintain the structure of the tubular endoplasmic reticulum network and the vacuole. Induces high curvature in membranes and causes membrane tubule formation. Involved in membrane/vesicle trafficking.
messages: The short lumenal loops between transmembrane domains 1 and 2 and between transmembrane domains 3 and 4 may impart a wedge-like configuration, thus deforming membranes.

214684:CNJ00730
gene id: 214684:CNJ00730
uniprot id: Q5KAR9
names: Similarity
messages: Belongs to the peptidase A1 family.

214684:CNF00050
gene id: 214684:CNF00050
uniprot id: Q5KFZ5
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

214684:CNE03040
gene id: 214684:CNE03040
uniprot id: Q5KGN0
names: Similarity
messages: Belongs to the SLA2 family.

214684:CNA00950
gene id: 214684:CNA00950
uniprot id: Q5KQ02
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCF family. EF3 subfamily.
messages: Cytoplasm

214684:CNA04760
gene id: 214684:CNA04760
uniprot id: Q5KNZ5
names: Subcellular Location Annotation
messages: Membrane

214684:CNK02240
gene id: 214684:CNK02240
uniprot id: Q5K9E3
names: Similarity
messages: Belongs to the universal ribosomal protein uL3 family.

214684:CNH01400
gene id: 214684:CNH01400
uniprot id: Q5KCL1
names: Similarity
messages: Belongs to the hexokinase family.

214684:CNA01960
gene id: 214684:CNA01960
uniprot id: Q5KPQ0
names: Similarity
messages: Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.

214684:CNA04680
gene id: 214684:CNA04680
uniprot id: P0CR32
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SDHAF2 family.
messages: Interacts with the flavoprotein subunit within the SDH catalytic dimer.
messages: Mitochondrion matrix
messages: Plays an essential role in the assembly of succinate dehydrogenase (SDH), an enzyme complex (also referred to as respiratory complex II) that is a component of both the tricarboxylic acid (TCA) cycle and the mitochondrial electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit of the SDH catalytic dimer.
messages: This protein may be expected to contain an N-terminal transit peptide but none has been predicted.

214684:CNC00460
gene id: 214684:CNC00460
uniprot id: P0CS14
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DDI1 family.
messages: Binds ubiquitin and polyubiquitinated proteins.
messages: Cytoplasm
messages: Probable aspartic protease. May be involved in the regulation of exocytosis. Acts as a linker between the 19S proteasome and polyubiquitinated proteins via UBA domain interactions with ubiquitin for their subsequent degradation. Required for S-phase checkpoint control.

214684:CNK01130
gene id: 214684:CNK01130
uniprot id: Q5K9Q6
names: Similarity
messages: Belongs to the CAND family.

214684:CNF01330
gene id: 214684:CNF01330
uniprot id: Q5KFL6
names: Similarity
messages: Belongs to the MIP18 family.

214684:CNE04090
gene id: 214684:CNE04090
uniprot id: Q5KGC7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-3 subunit J family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex.
messages: Cytoplasm

214684:CND02730
gene id: 214684:CND02730
uniprot id: P0CP98
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FKBP-type PPIase family. FKBP3/4 subfamily.
messages: Binds to histones H3 and H4.
messages: Inhibited by both FK506 and rapamycin.
messages: Nucleus
messages: PPIase that acts as a histone chaperone. Histone proline isomerase that increases the rate of cis-trans isomerization at prolines on the histone H3 N-terminal tail. Proline isomerization influences H3 methylation thereby regulating gene expression.

214684:CND04800
gene id: 214684:CND04800
uniprot id: Q5KHZ1
names: Similarity
messages: Belongs to the guanylate kinase family.

214684:CND02870
gene id: 214684:CND02870
uniprot id: P0CR52
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associated with the spliceosome.
messages: Belongs to the SLU7 family.
messages: Involved in pre-mRNA splicing.
messages: Nucleus

214684:CNF04530
gene id: 214684:CNF04530
uniprot id: Q5KER6
names: Similarity
messages: Belongs to the HEATR5 family.

214684:CNE01940
gene id: 214684:CNE01940
uniprot id: Q5KGY2
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

214684:CNC04200
gene id: 214684:CNC04200
uniprot id: Q5KK55
names: Similarity
messages: Belongs to the thioredoxin family.

214684:CNH00670
gene id: 214684:CNH00670
uniprot id: Q5KCD9
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.

214684:CNA04930
gene id: 214684:CNA04930
uniprot id: Q5KNX9
names: Similarity
messages: Belongs to the prefoldin subunit beta family.

214684:CNH02560
gene id: 214684:CNH02560
uniprot id: Q5KCX6
names: Similarity
messages: Belongs to the syntaxin family.

214684:CNG02790
gene id: 214684:CNG02790
uniprot id: Q5KDU0
uniprot id: Q5KDU1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase e subunit family.
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel.
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain. Minor subunit located with subunit a in the membrane.
messages: Mitochondrion inner membrane

214684:CNC06290
gene id: 214684:CNC06290
uniprot id: Q5KJJ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ANKZF1/VMS1 family.
messages: Cytoplasm

214684:CNH02450
gene id: 214684:CNH02450
uniprot id: Q5KCW4
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

214684:CNL04040
gene id: 214684:CNL04040
uniprot id: Q5K8Y6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BUD31 (G10) family.
messages: Nucleus

214684:CNB03150
gene id: 214684:CNB03150
uniprot id: Q5KM34
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane
messages: Mitochondrion inner membrane

214684:CNL04130
gene id: 214684:CNL04130
uniprot id: Q5K8X6
names: Similarity
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. CHEK2 subfamily.
messages: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. Aurora subfamily.

214684:CNH03090
gene id: 214684:CNH03090
uniprot id: Q5KD28
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

214684:CNN02340
gene id: 214684:CNN02340
uniprot id: Q5K6T5
names: Similarity
messages: Belongs to the cullin family.

214684:CND03460
gene id: 214684:CND03460
uniprot id: Q5KIC5
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL18 family.

214684:CNM00620
gene id: 214684:CNM00620
uniprot id: P0CN76
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the galactose-1-phosphate uridylyltransferase type 1 family.
messages: Binds 1 zinc ion per subunit. Zinc binding seems to play a structural role.
messages: Homodimer.

214684:CNK01920
gene id: 214684:CNK01920
uniprot id: Q5K9H4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MICOS complex subunit Mic12 family.
messages: Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane.
messages: Component of the mitochondrial contact site and cristae organizing system (MICOS) complex.
messages: Mitochondrion inner membrane

214684:CNE00800
gene id: 214684:CNE00800
uniprot id: Q5KH96
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

214684:CNG01240
gene id: 214684:CNG01240
uniprot id: Q5KEA0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the multicopper oxidase family.
messages: Secreted

214684:CNG03060
gene id: 214684:CNG03060
uniprot id: P0CS48
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associated with the spliceosome.
messages: Belongs to the WD repeat PRL1/PRL2 family.
messages: Cytoplasm
messages: Involved in pre-mRNA splicing and required for cell cycle progression at G2/M.
messages: Nucleus

214684:CNG00030
gene id: 214684:CNG00030
uniprot id: Q5KEM2
names: Similarity
messages: Belongs to the histidine acid phosphatase family.

214684:CNM01100
gene id: 214684:CNM01100
uniprot id: Q5K7W0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the VTS1 family.
messages: Monomer. Binds to RNA.
messages: P-body
messages: cytosol

214684:CNI00780
gene id: 214684:CNI00780
uniprot id: Q5KC02
names: Subcellular Location Annotation
messages: Nucleus
messages: kinetochore

214684:CNC03260
gene id: 214684:CNC03260
uniprot id: Q5KKE7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.

214684:CNJ00910
gene id: 214684:CNJ00910
uniprot id: Q5KAQ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the unc-50 family.
messages: Membrane

214684:CNI02660
gene id: 214684:CNI02660
uniprot id: Q5KBG1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transient receptor potential (TRP) ion channel family.
messages: Membrane

214684:CNA01070
gene id: 214684:CNA01070
uniprot id: Q5KPZ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ERG4/ERG24 family.
messages: Membrane

214684:CNH00520
gene id: 214684:CNH00520
uniprot id: P0CM80
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acts as component of the peripheral membrane COG complex that is involved in intra-Golgi protein trafficking. COG is located at the cis-Golgi, and regulates tethering of retrograde intra-Golgi vesicles and possibly a number of other membrane trafficking events (By similarity).
messages: Belongs to the COG6 family.
messages: Golgi apparatus membrane

214684:CNB03550
gene id: 214684:CNB03550
uniprot id: Q5KLZ1
names: Similarity
messages: Belongs to the amino acid/polyamine transporter 2 family.

214684:CNB05320
gene id: 214684:CNB05320
uniprot id: Q5KLG9
names: Similarity
messages: Belongs to the actin family.

214684:CNA05820
gene id: 214684:CNA05820
uniprot id: Q5KNP2
names: Subcellular Location Annotation
messages: Membrane

214684:CNF03830
gene id: 214684:CNF03830
uniprot id: P0CN24
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: As accessory component of the DNA polymerase epsilon (DNA polymerase II) participates in chromosomal DNA replication.
messages: Belongs to the DNA polymerase epsilon subunit B family.
messages: Heterotetramer. Consists of four subunits: POL2, DPB2, DPB3 and DPB4 (By similarity).
messages: In eukaryotes there are five DNA polymerases: alpha, beta, gamma, delta, and epsilon which are responsible for different reactions of DNA synthesis.
messages: Nucleus

214684:CNG03440
gene id: 214684:CNG03440
uniprot id: Q5KDM5
names: Similarity
messages: Belongs to the yippee family.

214684:CNK02200
gene id: 214684:CNK02200
uniprot id: Q5K9E7
names: Similarity
messages: Belongs to the peptidase S10 family.

214684:CNA05060
gene id: 214684:CNA05060
uniprot id: Q5KNW6
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

214684:CNI01350
gene id: 214684:CNI01350
uniprot id: Q5KBU7
names: Subcellular Location Annotation
messages: Membrane

214684:CNG00750
gene id: 214684:CNG00750
uniprot id: Q5KEE8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NADH dehydrogenase family.
messages: Mitochondrion inner membrane

214684:CNN00820
gene id: 214684:CNN00820
uniprot id: Q5K777
names: Similarity
messages: Belongs to the tRNA pseudouridine synthase TruA family.

214684:CNF04740
gene id: 214684:CNF04740
uniprot id: Q5KEP5
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

214684:CNA04920
gene id: 214684:CNA04920
uniprot id: P0CM90
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-3 subunit M family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex.
messages: Cytoplasm

214684:CNN01020
gene id: 214684:CNN01020
uniprot id: Q5K757
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the VPS11 family.
messages: Component of the homotypic vacuole fusion and vacuole protein sorting (HOPS) complex. Component of the class C core vacuole/endosome tethering (CORVET) complex.
messages: Vacuole membrane

214684:CNA07230
gene id: 214684:CNA07230
uniprot id: Q5KN99
names: Similarity
messages: Belongs to the glycosyltransferase 32 family.

214684:CNE01410
gene id: 214684:CNE01410
uniprot id: Q5KH36
names: Domain
names: Similarity
messages: A pair of annexin repeats may form one binding site for calcium and phospholipid.
messages: Belongs to the annexin family.

214684:CNL03730
gene id: 214684:CNL03730
uniprot id: Q5K918
names: Similarity
messages: Belongs to the GMC oxidoreductase family.

214684:CNC03980
gene id: 214684:CNC03980
uniprot id: P0CO52
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the kynureninase family.
messages: Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3-hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3-hydroxyanthranilic acid (3-OHAA), respectively.
messages: Cytoplasm
messages: Homodimer.

214684:CNL06640
gene id: 214684:CNL06640
uniprot id: Q5K879
names: Similarity
messages: Belongs to the class-I DAHP synthase family.

214684:CNB03960
gene id: 214684:CNB03960
uniprot id: Q5KLV2
names: Subcellular Location Annotation
messages: Nucleus speckle

214684:CNE01770
gene id: 214684:CNE01770
uniprot id: Q5KGZ9
names: Similarity
messages: Belongs to the STXBP/unc-18/SEC1 family.

214684:CNB03450
gene id: 214684:CNB03450
uniprot id: Q5KM02
uniprot id: Q5KM03
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PIGM family.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mannosyltransferase involved in glycosylphosphatidylinositol-anchor biosynthesis. Transfers the first alpha-1,4-mannose to GlcN-acyl-PI during GPI precursor assembly. Required for cell wall integrity.
messages: Membrane

214684:CNI00560
gene id: 214684:CNI00560
uniprot id: P0CN86
names: Function
messages: Trifunctional enzyme bearing the Gln amidotransferase (GATase) domain of anthranilate synthase, indole-glycerolphosphate synthase, and phosphoribosylanthranilate isomerase activities.

214684:CNF00440
gene id: 214684:CNF00440
uniprot id: P0CM42
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the battenin family.
messages: Involved in vacuolar transport and vacuole pH homeostasis. Also required for cytokinesis (By similarity).
messages: Vacuole membrane

214684:CNM00420
gene id: 214684:CNM00420
uniprot id: Q5K820
names: Similarity
messages: Belongs to the HARBI1 family.

214684:CNE02420
gene id: 214684:CNE02420
uniprot id: P0CO70
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MDM34 family.
messages: Component of the ER-mitochondria encounter structure (ERMES) or MDM complex, composed of MMM1, MDM10, MDM12 and MDM34.
messages: Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria. MDM34 is required for the interaction of the ER-resident membrane protein MMM1 and the outer mitochondrial membrane-resident beta-barrel protein MDM10.
messages: Lacks alpha-helical transmembrane segments, suggesting that it resides in the membrane via beta-sheet conformations similar to those predicted for other outer membrane proteins and porin.
messages: Mitochondrion outer membrane
messages: The SMP-LTD domain is a barrel-like domain that can bind various types of glycerophospholipids in its interior and mediate their transfer between two adjacent bilayers.

214684:CNI03080
gene id: 214684:CNI03080
uniprot id: Q5KBB9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ROT1 family.
messages: Endoplasmic reticulum membrane
messages: Required for normal levels of the cell wall 1,6-beta-glucan. Involved in a protein folding machinery chaperoning proteins acting in various physiological processes including cell wall synthesis and lysis of autophagic bodies.

214684:CNC04920
gene id: 214684:CNC04920
uniprot id: Q5KJY5
names: Subcellular Location Annotation
messages: Nucleus

214684:CND05510
gene id: 214684:CND05510
uniprot id: Q5KHS1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KRR1 family.
messages: Component of the ribosomal small subunit (SSU) processome composed of at least 40 protein subunits and snoRNA U3. Interacts with snoRNA U3. Interacts with MPP10, KRI1 and with ribosomal proteins RPS1A, RPS4A, RPS4B, RPS8A, RPS8B, RPS11A, RPS11B, RPS13, RPS24, RPS25, RPL4A, RPL7B, RPL8, RPL23, RPL25 and RPL28.
messages: Required for 40S ribosome biogenesis. Involved in nucleolar processing of pre-18S ribosomal RNA and ribosome assembly. Essential for vegetative growth.
messages: nucleolus

214684:CNN00460
gene id: 214684:CNN00460
uniprot id: Q5K7B2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: Mitochondrion
messages: The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

214684:CNH00470
gene id: 214684:CNH00470
uniprot id: Q5KCB7
names: Similarity
messages: Belongs to the SMP-30/CGR1 family.

214684:CNJ00820
gene id: 214684:CNJ00820
uniprot id: Q5KAR0
names: Subcellular Location Annotation
messages: Membrane

214684:CND03220
gene id: 214684:CND03220
uniprot id: Q5KIE8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the snRNP Sm proteins family. SmF/LSm6 subfamily.
messages: Nucleus

214684:CNC04830
gene id: 214684:CNC04830
uniprot id: Q5KJZ4
names: Similarity
messages: Belongs to the indoleamine 2,3-dioxygenase family.

214684:CNA04230
gene id: 214684:CNA04230
uniprot id: Q5KP45
names: Similarity
messages: Belongs to the cyclin family.

214684:CNA05630
gene id: 214684:CNA05630
uniprot id: Q5KNR0
names: Function
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

214684:CNB01150
gene id: 214684:CNB01150
uniprot id: Q5KMM7
names: Similarity
messages: Belongs to the threonine synthase family.

214684:CNM02160
gene id: 214684:CNM02160
uniprot id: Q5K7K0
names: Similarity
messages: Belongs to the GILT family.

214684:CNH02480
gene id: 214684:CNH02480
uniprot id: Q5KCW7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the helicase family. PIF1 subfamily.
messages: DNA-dependent ATPase and 5'-3' DNA helicase required for the maintenance of both mitochondrial and nuclear genome stability.
messages: Mitochondrion
messages: Monomer.
messages: Nucleus

214684:CNJ01520
gene id: 214684:CNJ01520
uniprot id: Q5KAJ0
names: Similarity
messages: Belongs to the DCP1 family.

214684:CNE05000
gene id: 214684:CNE05000
uniprot id: Q5KG36
names: Similarity
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Homodimer.

214684:CNL04610
gene id: 214684:CNL04610
uniprot id: Q5K8T0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SF3B4 family.
messages: Nucleus

214684:CNE00990
gene id: 214684:CNE00990
uniprot id: Q5KH75
names: Similarity
messages: Belongs to the protein kinase superfamily. ADCK protein kinase family.

214684:CNL05350
gene id: 214684:CNL05350
uniprot id: Q5K8K4
names: Subcellular Location Annotation
messages: Cytoplasm

214684:CND05300
gene id: 214684:CND05300
uniprot id: Q5KHU0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase PH family.
messages: nucleolus

214684:CNC04540
gene id: 214684:CNC04540
uniprot id: Q5KK21
names: Similarity
messages: Belongs to the universal ribosomal protein uS17 family.

214684:CNN01410
gene id: 214684:CNN01410
uniprot id: Q5K721
names: Similarity
messages: Belongs to the peptidase S9B family.

214684:CNI03430
gene id: 214684:CNI03430
uniprot id: P0CR68
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SPT4 family.
messages: Component of the SPT4-SPT5 complex. Interacts with RNA polymerase II (By similarity).
messages: Nucleus
messages: The SPT4-SPT5 complex mediates both activation and inhibition of transcription elongation, and plays a role in pre-mRNA processing. This complex seems to be important for the stability of the RNA polymerase II elongation machinery on the chromatin template but not for the inherent ability of this machinery to translocate down the gene (By similarity).
messages: centromere

214684:CNK00560
gene id: 214684:CNK00560
uniprot id: Q5K9W1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-B family.
messages: Nucleus

214684:CNN01560
gene id: 214684:CNN01560
uniprot id: P0CL98
names: Similarity
messages: Belongs to the acetokinase family.

214684:CNF02140
gene id: 214684:CNF02140
uniprot id: Q5KFD3
names: Similarity
messages: Belongs to the universal ribosomal protein uS5 family.

214684:CNA04420
gene id: 214684:CNA04420
uniprot id: Q5KP26
names: Cofactor
names: Function
messages: Accepts electrons from ETF and reduces ubiquinone.
messages: Binds 1 [4Fe-4S] cluster.

214684:CND06410
gene id: 214684:CND06410
uniprot id: Q5KHI1
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

214684:CNG03650
gene id: 214684:CNG03650
uniprot id: P0CR04
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent RNA helicase involved in 40S ribosomal subunit biogenesis. Required for the processing and cleavage of 35S pre-rRNA at sites A0, A1, and A2, leading to mature 18S rRNA.
messages: Belongs to the DEAD box helicase family. DDX52/ROK1 subfamily.
messages: Interacts with the U3 snoRNA and is associated with the 90S and 40S pre-ribosomes.
messages: The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.
messages: nucleolus

214684:CNC01030
gene id: 214684:CNC01030
uniprot id: Q5KL23
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

214684:CNF02510
gene id: 214684:CNF02510
uniprot id: Q5KF98
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

214684:CNA07980
gene id: 214684:CNA07980
uniprot id: Q5KN25
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL34 family.

214684:CNB00260
gene id: 214684:CNB00260
uniprot id: P0CR40
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SEC23/SEC24 family. SEC24 subfamily.
messages: COPII-coated vesicle membrane
messages: Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules (By similarity).
messages: Cytoplasm
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: The COPII coat is composed of at least 5 proteins: the SEC23/24 complex, the SEC13/31 complex, and the protein SAR1. Golgi apparatus membrane; Peripheral membrane protein; Cytoplasmic side.

214684:CND04750
gene id: 214684:CND04750
uniprot id: Q5KHZ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic RPB7/RPC8 RNA polymerase subunit family.
messages: Nucleus

214684:CNE03100
gene id: 214684:CNE03100
uniprot id: Q5KGM4
names: Similarity
messages: Belongs to the XFP family.

214684:CNL06550
gene id: 214684:CNL06550
uniprot id: Q5K890
names: Similarity
messages: Belongs to the OMP decarboxylase family.

214684:CNB05290
gene id: 214684:CNB05290
uniprot id: Q5KLH1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM208 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

214684:CNE02120
gene id: 214684:CNE02120
uniprot id: Q5KGW3
names: Domain
names: Function
names: Similarity
messages: Belongs to the damage-control phosphatase family. Sugar phosphate phosphatase III subfamily.
messages: Metal-dependent phosphatase that shows phosphatase activity against several substrates, including fructose-1-phosphate and fructose-6-phosphate. Its preference for fructose-1-phosphate, a strong glycating agent that causes DNA damage rather than a canonical yeast metabolite, suggests a damage-control function in hexose phosphate metabolism.
messages: Subfamily III proteins have a conserved RTxK motif about 40-50 residues from the C-terminus; the threonine may be replaced by serine or cysteine.

214684:CNJ01560
gene id: 214684:CNJ01560
uniprot id: Q5KAI5
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL20 family.

214684:CNB04100
gene id: 214684:CNB04100
uniprot id: Q5KLT8
names: Subcellular Location Annotation
messages: nucleolus

214684:CND03570
gene id: 214684:CND03570
uniprot id: P0CM20
names: Function
names: Miscellaneous
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArgJ family.
messages: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of acetylglutamate from glutamate and acetyl-CoA, and of ornithine by transacetylation between acetylornithine and glutamate.
messages: Heterodimer of an alpha and a beta chain.
messages: Mitochondrion matrix
messages: The alpha and beta chains are autoproteolytically processed from a single precursor protein within the mitochondrion.
messages: This protein may be expected to contain an N-terminal transit peptide but none has been predicted.

214684:CNH01900
gene id: 214684:CNH01900
uniprot id: P0CS22
names: Cofactor
names: PTM
names: Similarity
names: Subunit
messages: Binds 2 nickel ions per subunit.
messages: Carboxylation allows a single lysine to coordinate two nickel ions.
messages: Homohexamer.
messages: In the C-terminal section; belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family.

214684:CNA06240
gene id: 214684:CNA06240
uniprot id: Q5KNJ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fatty acid desaturase type 1 family. DEGS subfamily.
messages: Membrane

214684:CNA03910
gene id: 214684:CNA03910
uniprot id: Q5KP77
names: Similarity
messages: Belongs to the gamma-BBH/TMLD family.

214684:CNF04090
gene id: 214684:CNF04090
uniprot id: Q5KEV7
names: Subcellular Location Annotation
messages: Membrane

214684:CND02060
gene id: 214684:CND02060
uniprot id: Q5KIR2
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

214684:CNA07590
gene id: 214684:CNA07590
uniprot id: Q5KN63
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the snRNP Sm proteins family.
messages: Binds specifically to the 3'-terminal U-tract of U6 snRNA.
messages: LSm subunits form a heteromer with a doughnut shape.
messages: Nucleus

214684:CNG03820
gene id: 214684:CNG03820
uniprot id: Q5KDI9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protoporphyrinogen/coproporphyrinogen oxidase family. Protoporphyrinogen oxidase subfamily.
messages: Binds 1 FAD per subunit.
messages: Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX.
messages: Mitochondrion inner membrane

214684:CNB00510
gene id: 214684:CNB00510
uniprot id: Q5KMT9
uniprot id: Q5KMU0
names: Subcellular Location Annotation
messages: Membrane

214684:CNE01590
gene id: 214684:CNE01590
uniprot id: Q5KH16
names: Similarity
messages: Belongs to the NKAP family.

214684:CNG03330
gene id: 214684:CNG03330
uniprot id: Q5KDN4
names: Similarity
messages: Belongs to the glycosyl hydrolase 47 family.

214684:CNA08080
gene id: 214684:CNA08080
uniprot id: Q5KN16
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SKP1 family.
messages: Component of the SCF (SKP1-CUL1-F-box protein) E3 ubiquitin ligase complexes.
messages: Essential component of the SCF (SKP1-CUL1-F-box protein) E3 ubiquitin ligase complexes, which mediate the ubiquitination and subsequent proteasomal degradation of target proteins.

214684:CNK02850
gene id: 214684:CNK02850
uniprot id: Q5K984
names: Subcellular Location Annotation
messages: Membrane

214684:CNG04380
gene id: 214684:CNG04380
uniprot id: Q5KDD4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat PWP2 family.
messages: nucleolus

214684:CNC02370
gene id: 214684:CNC02370
uniprot id: P0CP30
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NPL4 family.
messages: Endoplasmic reticulum membrane
messages: Involved in the import of nuclear-targeted proteins into the nucleus and the export of poly(A) RNA out of the nucleus. Has a role in the endoplasmic reticulum-associated degradation (ERAD) pathway (By similarity).
messages: Nucleus membrane
messages: perinuclear region

214684:CNI04130
gene id: 214684:CNI04130
uniprot id: Q5KB15
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

214684:CND04140
gene id: 214684:CND04140
uniprot id: P0CO34
names: Domain
names: Function
names: Similarity
messages: Belongs to the IPK1 type 2 family.
messages: Phosphorylates Ins(1,3,4,5,6)P5 at position 2 to form Ins(1,2,3,4,5,6)P6 (InsP6 or phytate).
messages: The EXKPK motif is conserved in inositol-pentakisphosphate 2-kinases of both family 1 and 2.

214684:CND03150
gene id: 214684:CND03150
uniprot id: Q5KIF5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptobrevin family.
messages: Endoplasmic reticulum membrane
messages: Membrane

214684:CNJ03200
gene id: 214684:CNJ03200
uniprot id: Q5KA36
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

214684:CNC05820
gene id: 214684:CNC05820
uniprot id: Q5KJP3
names: Similarity
messages: Belongs to the tRNA-intron endonuclease family.

214684:CNM01810
gene id: 214684:CNM01810
uniprot id: Q5K7N6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFS4 subunit family.
messages: Mitochondrion inner membrane

214684:CNM01520
gene id: 214684:CNM01520
uniprot id: Q5K7R6
names: Similarity
messages: Belongs to the heat shock protein 90 family.

214684:CNJ01760
gene id: 214684:CNJ01760
uniprot id: Q5KAG7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GLE1 family.
messages: nuclear pore complex

214684:CND01200
gene id: 214684:CND01200
uniprot id: Q5KIZ5
names: Similarity
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. Homocitrate synthase LYS20/LYS21 subfamily.

214684:CNC01070
gene id: 214684:CNC01070
uniprot id: Q5KL19
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GcvP family.
messages: Mitochondrion
messages: The glycine cleavage system catalyzes the degradation of glycine.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

214684:CNA00880
gene id: 214684:CNA00880
uniprot id: Q5KQ09
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

214684:CND01730
gene id: 214684:CND01730
uniprot id: Q5KIU4
names: Subcellular Location Annotation
messages: Membrane

214684:CNK01420
gene id: 214684:CNK01420
uniprot id: Q5K9M8
names: Similarity
messages: Belongs to the serine/threonine dehydratase family.

214684:CNN00950
gene id: 214684:CNN00950
uniprot id: Q5K764
names: Similarity
messages: Belongs to the SAS10 family.

214684:CNA02220
gene id: 214684:CNA02220
uniprot id: Q5KPM8
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL30 family.

214684:CNG01500
gene id: 214684:CNG01500
uniprot id: P0CQ52
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eL8 family.
messages: Common component of the spliceosome and rRNA processing machinery. In association with the spliceosomal U4/U6.U5 tri-snRNP particle, required for splicing of pre-mRNA. In association with box C/D snoRNPs, required for processing of pre-ribosomal RNA (rRNA) and site-specific 2'-O-methylation of substrate RNAs. Essential for the accumulation and stability of U4 snRNA, U6 snRNA, and box C/D snoRNAs (By similarity).
messages: Component of the U3 snoRNP particle. Binds to the C'/D and B/C motifs in U3 snoRNA. Component of the 25S U4/U6.U5 tri-snRNP particle, a subcomplex of the spliceosome. Binds to the 5' stem-loop of U4 snRNA (By similarity).
messages: nucleolus

214684:CNM01330
gene id: 214684:CNM01330
uniprot id: P0CO76
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 7 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).
messages: Component of the Mediator complex.
messages: Nucleus

214684:CNH00280
gene id: 214684:CNH00280
uniprot id: P0CQ90
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: ATP-binding RNA helicase involved in the biogenesis of 60S ribosomal subunits and is required for the normal formation of 25S and 5.8S rRNAs.
messages: Belongs to the DEAD box helicase family. DDX24/MAK5 subfamily.
messages: The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.
messages: nucleolus

214684:CNI01600
gene id: 214684:CNI01600
uniprot id: Q5KBS2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DIM1 family.
messages: Essential role in pre-mRNA splicing. Also essential for entry into mitosis (G2/M progression) as well as for chromosome segregation during mitosis.
messages: Nucleus

214684:CNN01400
gene id: 214684:CNN01400
uniprot id: Q5K722
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Membrane

214684:CNF03660
gene id: 214684:CNF03660
uniprot id: Q5KEZ5
names: Similarity
messages: Belongs to the peptidase C13 family.

214684:CNM01730
gene id: 214684:CNM01730
uniprot id: A0A0S2LJ61
uniprot id: Q5K7P5
names: Similarity
messages: Belongs to the transketolase family.

214684:CNC05160
gene id: 214684:CNC05160
uniprot id: Q5KJW2
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

214684:CNA03600
gene id: 214684:CNA03600
uniprot id: Q5KP97
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type II topoisomerase family.
messages: Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double-strand breaks.
messages: Homodimer.

214684:CND00430
gene id: 214684:CND00430
uniprot id: Q5KJ70
names: Similarity
messages: Belongs to the TMEM14 family.

214684:CNB04410
gene id: 214684:CNB04410
uniprot id: Q5KLQ8
names: Similarity
messages: Belongs to the SUA5 family.

214684:CNH03640
gene id: 214684:CNH03640
uniprot id: Q5KD83
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetate uptake transporter (AceTr) (TC 2.A.96) family.
messages: Membrane

214684:CNK02980
gene id: 214684:CNK02980
uniprot id: Q5K971
names: Subcellular Location Annotation
messages: Membrane

214684:CND06030
gene id: 214684:CND06030
uniprot id: Q5KHL8
names: Subcellular Location Annotation
messages: Membrane

214684:CND03580
gene id: 214684:CND03580
uniprot id: P0CP76
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polysaccharide deacetylase family.
messages: Cell membrane
messages: Hydrolyzes the N-acetamido groups of N-acetyl-D-glucosamine residues in chitin to form chitosan and acetate (By similarity). Chitosan is required to anchor melanin to the cell wall, for maintenance of cell wall integrity, and for proper cytokinesis (By similarity). Chitosan offers an advantage during infection as it is less readily detected than chitin by host immunosurveillance mechanisms (By similarity).

214684:CNK00170
gene id: 214684:CNK00170
uniprot id: Q5K9Z4
names: Function
names: Similarity
messages: Belongs to the tubulin family.
messages: Tubulin is the major constituent of microtubules. The gamma chain is found at microtubule organizing centers (MTOC) such as the spindle poles or the centrosome.

214684:CNA00780
gene id: 214684:CNA00780
uniprot id: Q5KQ18
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prohibitin family.
messages: Mitochondrion inner membrane

214684:CNI00890
gene id: 214684:CNI00890
uniprot id: Q5KBZ1
names: Similarity
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.

214684:CNB04370
gene id: 214684:CNB04370
uniprot id: P0CR72
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPT6 family.
messages: Nucleus
messages: Plays a role in maintenance of chromatin structure during RNA polymerase II transcription elongation thereby repressing transcription initiation from cryptic promoters. Mediates the reassembly of nucleosomes onto the promoters of at least a selected set of genes during repression; the nucleosome reassembly is essential for transcriptional repression (By similarity).

214684:CNE00760
gene id: 214684:CNE00760
uniprot id: Q5KHA0
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

214684:CNB04880
gene id: 214684:CNB04880
uniprot id: P0CQ58
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eS1 family.
messages: Component of the small ribosomal subunit. Mature ribosomes consist of a small (40S) and a large (60S) subunit. The 40S subunit contains about 33 different proteins and 1 molecule of RNA (18S). The 60S subunit contains about 49 different proteins and 3 molecules of RNA (25S, 5.8S and 5S).
messages: Cytoplasm

214684:CNB01990
gene id: 214684:CNB01990
uniprot id: P0CM22
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Binds 2 Zn(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: In the 2nd section; belongs to the EPSP synthase family.
messages: In the 3rd section; belongs to the shikimate kinase family.
messages: In the 4th section; belongs to the type-I 3-dehydroquinase family.
messages: In the C-terminal section; belongs to the shikimate dehydrogenase family.
messages: In the N-terminal section; belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
messages: The AROM polypeptide catalyzes 5 consecutive enzymatic reactions in prechorismate polyaromatic amino acid biosynthesis.

214684:CNF00140
gene id: 214684:CNF00140
uniprot id: Q5KFY6
names: Similarity
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.

214684:CNN01890
gene id: 214684:CNN01890
uniprot id: Q5K6X2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.
messages: Membrane

214684:CNN01030
gene id: 214684:CNN01030
uniprot id: Q5K756
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane
messages: Mitochondrion inner membrane

214684:CNB05770
gene id: 214684:CNB05770
uniprot id: Q5KLC4
names: Subcellular Location Annotation
messages: Membrane

214684:CNF03690
gene id: 214684:CNF03690
uniprot id: Q5KEZ2
names: Subcellular Location Annotation
messages: Membrane

214684:CNA03190
gene id: 214684:CNA03190
uniprot id: Q5KPD4
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane.
messages: Component of the mitochondrial contact site and cristae organizing system (MICOS) complex.
messages: Mitochondrion inner membrane

214684:CNL06110
gene id: 214684:CNL06110
uniprot id: Q5K8D2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTP-binding elongation factor family. LepA subfamily.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Mitochondrion inner membrane
messages: Promotes mitochondrial protein synthesis. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Binds to mitochondrial ribosomes in a GTP-dependent manner.

214684:CND01790
gene id: 214684:CND01790
uniprot id: Q5KIT8
names: Similarity
messages: Belongs to the NOP10 family.

214684:CNA01540
gene id: 214684:CNA01540
uniprot id: P0CR02
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: ATP-binding RNA helicase involved in 40S ribosomal subunit biogenesis and is required for the normal formation of 18S rRNAs through pre-rRNA processing at A0, A1 and A2 sites. Required for vegetative growth (By similarity).
messages: Belongs to the DEAD box helicase family. DDX49/DBP8 subfamily.
messages: The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.
messages: nucleolus

214684:CNI04050
gene id: 214684:CNI04050
uniprot id: P0CM08
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YAF9 family.
messages: Component of the SWR1 chromatin-remodeling complex and of the NuA4 histone acetyltransferase complex.
messages: Component of the SWR1 complex which mediates the ATP-dependent exchange of histone H2A for the H2A variant HZT1 leading to transcriptional regulation of selected genes by chromatin remodeling. Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histones H4 and H2A. The NuA4 complex is also involved in DNA repair. Yaf9 may also be required for viability in conditions in which the structural integrity of the spindle is compromised (By similarity).
messages: Cytoplasm
messages: Nucleus
messages: The coiled-coil domain is required for assembly into the NuA4 complex.

214684:CNC03150
gene id: 214684:CNC03150
uniprot id: Q5KKF8
names: Subcellular Location Annotation
messages: Nucleus

214684:CNA02040
gene id: 214684:CNA02040
uniprot id: Q5KPP3
names: Subcellular Location Annotation
messages: Membrane

214684:CNG04370
gene id: 214684:CNG04370
uniprot id: Q5KDD5
names: Subcellular Location Annotation
messages: spindle

214684:CNB05270
gene id: 214684:CNB05270
uniprot id: Q5KLH3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UTP6 family.
messages: nucleolus

214684:CNJ01940
gene id: 214684:CNJ01940
uniprot id: Q07801
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dihydrofolate reductase family.
messages: Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity).
messages: Monomer.

214684:CNB00740
gene id: 214684:CNB00740
uniprot id: Q5KMR6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.
messages: cytoskeleton

214684:CNC06560
gene id: 214684:CNC06560
uniprot id: Q5KJH2
names: Subcellular Location Annotation
messages: Nucleus

214684:CNK00300
gene id: 214684:CNK00300
uniprot id: P0CM72
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CHS7 family.
messages: Chaperone required for the export of the chitin synthase CHS3 from the endoplasmic reticulum.
messages: Endoplasmic reticulum membrane
messages: Interacts with CHS3.

214684:CNA05910
gene id: 214684:CNA05910
uniprot id: Q5KNN2
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.

214684:CNE04540
gene id: 214684:CNE04540
uniprot id: Q5KG80
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DASH complex DAD1 family.
messages: Nucleus
messages: kinetochore
messages: spindle

214684:CNC06300
gene id: 214684:CNC06300
uniprot id: P0CR62
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sorting nexin family.
messages: Endosome membrane
messages: Preautophagosomal structure membrane
messages: Sorting nexin, involved in the separation or division of vacuoles throughout the entire life cycle of the cells. Involved in retrieval of late-Golgi SNAREs from post-Golgi endosomes to the trans-Golgi network, for cytoplasm to vacuole transport (Cvt), autophagy, mitophagy, and pexophagy.
messages: The PX domain binds phosphatidylinositol 3-phosphate which is necessary for peripheral membrane localization to the perivacuolar punctate structures.
messages: cytosol

214684:CNC06590
gene id: 214684:CNC06590
uniprot id: P0CP68
names: Activity Regulation
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Activated by tyrosine and threonine phosphorylation.
messages: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. HOG1 sub-subfamily.
messages: Cytoplasm
messages: Dually phosphorylated on Thr-171 and Tyr-173, which activates the enzyme (By similarity). Phosphorylated by PBS2 after osmotic stress.
messages: Mitogen-activated protein kinase involved in a signal transduction pathway that is activated by changes in the osmolarity of the extracellular environment. Controls osmotic regulation of transcription of target genes. Also involved in response UV radiations and mediates the sensitivity to fludioxonil, an agricultural fungicide.
messages: Nucleus
messages: The TXY motif contains the threonine and tyrosine residues whose phosphorylation activates the MAP kinases.

214684:CNB01420
gene id: 214684:CNB01420
uniprot id: P0CN48
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-3 subunit D family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex.
messages: Cytoplasm
messages: The RNA gate region regulates mRNA cap recognition to prevent promiscuous mRNA-binding before assembly of eif3d into the full eukaryotic translation initiation factor 3 (eIF-3) complex.
messages: mRNA cap-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. In the eIF-3 complex, eif3d specifically recognizes and binds the 7-methylguanosine cap of a subset of mRNAs.

214684:CNG01740
gene id: 214684:CNG01740
uniprot id: Q5KE49
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

214684:CNB02280
gene id: 214684:CNB02280
uniprot id: Q5KMB4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the archaeal Rpo11/eukaryotic RPB11/RPC19 RNA polymerase subunit family.
messages: Nucleus

214684:CNB04770
gene id: 214684:CNB04770
uniprot id: Q5KLM2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPC1 family.
messages: Membrane

214684:CNA07500
gene id: 214684:CNA07500
uniprot id: Q5KN72
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RAD23 family.
messages: Cytoplasm
messages: Multiubiquitin chain receptor involved in modulation of proteasomal degradation. Involved in nucleotide excision repair.
messages: Nucleus

214684:CNJ01920
gene id: 214684:CNJ01920
uniprot id: Q5KAF2
names: Similarity
messages: Belongs to the universal ribosomal protein uL4 family.

214684:CND04310
gene id: 214684:CND04310
uniprot id: Q5KI40
names: Similarity
messages: Belongs to the protein kinase superfamily.

214684:CNJ02510
gene id: 214684:CNJ02510
uniprot id: Q5KA94
names: Similarity
messages: Belongs to the TIP41 family.

214684:CNL06490
gene id: 214684:CNL06490
uniprot id: Q5K896
names: Subcellular Location Annotation
messages: Membrane

214684:CNB05540
gene id: 214684:CNB05540
uniprot id: Q5KLE7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1A family.
messages: Cytoplasm
messages: Nucleus
messages: The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits.

214684:CNB05620
gene id: 214684:CNB05620
uniprot id: P0CL86
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 3-HAO family.
messages: Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate.
messages: Cytoplasm

214684:CND05450
gene id: 214684:CND05450
uniprot id: Q5KHS6
names: Subcellular Location Annotation
messages: nucleolus

214684:CNG03780
gene id: 214684:CNG03780
uniprot id: Q5KDJ3
names: Similarity
messages: Belongs to the WD repeat CDC20/Fizzy family.

214684:CNB04920
gene id: 214684:CNB04920
uniprot id: Q5KLK7
names: Similarity
messages: Belongs to the GTP cyclohydrolase I family.

214684:CNK01320
gene id: 214684:CNK01320
uniprot id: Q5K9N8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the activator 1 large subunit family.
messages: Nucleus

214684:CNJ03280
gene id: 214684:CNJ03280
uniprot id: Q5KA28
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

214684:CNL06200
gene id: 214684:CNL06200
uniprot id: Q5K8C4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SRP14 family.
messages: Component of a fungal signal recognition particle (SRP) complex that consists of a 7SL RNA molecule (scR1) and at least six protein subunits: SRP72, SRP68, SRP54, SEC65, SRP21 and SRP14.
messages: Component of the signal recognition particle (SRP) complex, a ribonucleoprotein complex that mediates the cotranslational targeting of secretory and membrane proteins to the endoplasmic reticulum (ER).
messages: Cytoplasm

214684:CNJ02120
gene id: 214684:CNJ02120
uniprot id: Q5KAD2
names: Subunit
messages: Homodimer.

214684:CND00580
gene id: 214684:CND00580
uniprot id: Q5KJ57
names: Subcellular Location Annotation
messages: Cytoplasm

214684:CNA06000
gene id: 214684:CNA06000
uniprot id: Q5KNM2
names: Similarity
messages: In the central section; belongs to the metallo-dependent hydrolases superfamily. DHOase family. CAD subfamily.

214684:CNA07120
gene id: 214684:CNA07120
uniprot id: Q5KNB0
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.

214684:CNL03840
gene id: 214684:CNL03840
uniprot id: Q5K905
names: Domain
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.
messages: The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate.

214684:CNE03330
gene id: 214684:CNE03330
uniprot id: Q5KGK1
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

214684:CNC05010
gene id: 214684:CNC05010
uniprot id: Q5KJX7
names: Function
messages: Cleaves the gamma-glutamyl peptide bond of glutathione and glutathione conjugates.

214684:CNI02880
gene id: 214684:CNI02880
uniprot id: Q5KBD9
names: Similarity
messages: Belongs to the OSBP family.

214684:CNH00410
gene id: 214684:CNH00410
uniprot id: Q5KCB1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELP4 family.
messages: Cytoplasm
messages: Nucleus

214684:CNB02890
gene id: 214684:CNB02890
uniprot id: Q5KM54
names: Similarity
messages: Belongs to the type-1 OGG1 family.

214684:CNI04230
gene id: 214684:CNI04230
uniprot id: P0CQ64
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associated with the spliceosome.
messages: Belongs to the CWC24 family.
messages: Involved in pre-mRNA splicing.
messages: Nucleus

214684:CNI03590
gene id: 214684:CNI03590
uniprot id: Q5KB69
names: Similarity
messages: Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.

214684:CND03280
gene id: 214684:CND03280
uniprot id: Q5KIE2
names: Similarity
messages: Belongs to the ATPase delta chain family.

214684:CNA04830
gene id: 214684:CNA04830
uniprot id: Q5KNY9
names: Similarity
messages: Belongs to the PP2C family.

214684:CNG01660
gene id: 214684:CNG01660
uniprot id: Q5KE57
names: Similarity
messages: Belongs to the exportin family.

214684:CNB01030
gene id: 214684:CNB01030
uniprot id: Q5KMN9
names: Subcellular Location Annotation
messages: Membrane

214684:CNG02810
gene id: 214684:CNG02810
uniprot id: Q5KDT8
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family.

214684:CNF03620
gene id: 214684:CNF03620
uniprot id: Q5KEZ9
names: Similarity
messages: Belongs to the glycosyl hydrolase 20 family.

214684:CNG00670
gene id: 214684:CNG00670
uniprot id: Q5KEF6
names: Similarity
messages: Belongs to the ZNF598/HEL2 family.

214684:CND06310
gene id: 214684:CND06310
uniprot id: Q5KHJ0
names: Subcellular Location Annotation
messages: Nucleus

214684:CNK01360
gene id: 214684:CNK01360
uniprot id: Q5K9N4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

214684:CNF01800
gene id: 214684:CNF01800
uniprot id: Q5KFG8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

214684:CNF04690
gene id: 214684:CNF04690
uniprot id: Q5KEQ0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EMC1 family.
messages: Component of the ER membrane protein complex (EMC).
messages: Endoplasmic reticulum membrane
messages: Membrane

214684:CND04450
gene id: 214684:CND04450
uniprot id: Q5KI26
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DASH complex SPC19 family.
messages: Nucleus
messages: kinetochore

214684:CND05070
gene id: 214684:CND05070
uniprot id: P0CS72
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ENY2 family.
messages: Component of the nuclear pore complex (NPC)-associated TREX-2 complex (transcription and export complex 2), composed of at least SUS1, SAC3, THP1, SEM1, and CDC31. TREX-2 contains 2 SUS1 chains. The TREX-2 complex interacts with the nucleoporin NUP1. Component of the 1.8 MDa SAGA transcription coactivator-HAT complex. SAGA is built of 5 distinct domains with specialized functions. Within the SAGA complex, SUS1, SGF11, SGF73 and UBP8 form an additional subcomplex of SAGA called the DUB module (deubiquitination module). Interacts directly with THP1, SAC3, SGF11, and with the RNA polymerase II.
messages: Involved in mRNA export coupled transcription activation by association with both the TREX-2 and the SAGA complexes. At the promoters, SAGA is required for recruitment of the basal transcription machinery. It influences RNA polymerase II transcriptional activity through different activities such as TBP interaction and promoter selectivity, interaction with transcription activators, and chromatin modification through histone acetylation and deubiquitination. Within the SAGA complex, participates in a subcomplex required for deubiquitination of H2B and for the maintenance of steady-state H3 methylation levels. The TREX-2 complex functions in docking export-competent ribonucleoprotein particles (mRNPs) to the nuclear entrance of the nuclear pore complex (nuclear basket). TREX-2 participates in mRNA export and accurate chromatin positioning in the nucleus by tethering genes to the nuclear periphery. May also be involved in cytoplasmic mRNA decay by interaction with components of P-bodies (By similarity).
messages: P-body
messages: nucleoplasm

214684:CNB04220
gene id: 214684:CNB04220
uniprot id: Q5KLS6
names: Similarity
messages: Belongs to the eukaryotic initiation factor 4E family.

214684:CNG00270
gene id: 214684:CNG00270
uniprot id: P0CR36
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the reduction of 3-ketodihydrosphingosine (KDS) to dihydrosphingosine (DHS).
messages: Endoplasmic reticulum membrane

214684:CNG00800
gene id: 214684:CNG00800
uniprot id: Q5KEE4
names: Similarity
messages: Belongs to the RRP7 family.

214684:CNL05860
gene id: 214684:CNL05860
uniprot id: Q5K8F7
names: Function
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase family.
messages: Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate.

214684:CNI01040
gene id: 214684:CNI01040
uniprot id: Q5KBX6
names: Subcellular Location Annotation
messages: Membrane

214684:CNG03310
gene id: 214684:CNG03310
uniprot id: Q5KDN6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

214684:CND02800
gene id: 214684:CND02800
uniprot id: Q5KII9
names: Similarity
messages: Belongs to the FGGY kinase family.

214684:CNE00690
gene id: 214684:CNE00690
uniprot id: Q5KHA7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NSE4 family.
messages: Component of the SMC5-SMC6 complex, that promotes sister chromatid alignment after DNA damage and facilitates double-stranded DNA breaks (DSBs) repair via homologous recombination between sister chromatids.
messages: Component of the SMC5-SMC6 complex.
messages: Nucleus

214684:CNC06660
gene id: 214684:CNC06660
uniprot id: Q5KJG1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the V-ATPase C subunit family.
messages: Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment. Subunit C is necessary for the assembly of the catalytic sector of the enzyme and is likely to have a specific function in its catalytic activity.
messages: V-ATPase is a heteromultimeric enzyme composed of a peripheral catalytic V1 complex (components A to H) attached to an integral membrane V0 proton pore complex.

214684:CNC03330
gene id: 214684:CNC03330
uniprot id: Q5KKE0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SQS1 family.
messages: Cytoplasm
messages: Nucleus

214684:CNH01260
gene id: 214684:CNH01260
uniprot id: Q5KCJ7
names: Similarity
messages: Belongs to the PDCD5 family.

214684:CNB03780
gene id: 214684:CNB03780
uniprot id: P0CR42
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. SET5 subfamily.
messages: Cytoplasm
messages: Nucleus
messages: Putative protein lysine methyltransferase.

214684:CNE03480
gene id: 214684:CNE03480
uniprot id: Q5KGI6
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

214684:CNM02250
gene id: 214684:CNM02250
uniprot id: Q5K7J2
names: Similarity
messages: Belongs to the PIAS family.

214684:CNH03230
gene id: 214684:CNH03230
uniprot id: Q5KD43
names: Similarity
messages: Belongs to the ARS2 family.

214684:CNA08050
gene id: 214684:CNA08050
uniprot id: Q5KN19
names: Function
names: Similarity
messages: Belongs to the dihydroxyacetone kinase (DAK) family.
messages: Catalyzes both the phosphorylation of dihydroxyacetone and of glyceraldehyde.

214684:CNF00830
gene id: 214684:CNF00830
uniprot id: Q5KFR5
names: Similarity
messages: Belongs to the SH3YL1 family.

214684:CNA01000
gene id: 214684:CNA01000
uniprot id: Q5KPZ7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

214684:CNA06670
gene id: 214684:CNA06670
uniprot id: Q5KNF4
names: Function
messages: Participates in the formation of the lipid-linked precursor oligosaccharide for N-glycosylation. Involved in assembling the dolichol-pyrophosphate-GlcNAc(2)-Man(5) intermediate on the cytoplasmic surface of the ER.

214684:CNC01590
gene id: 214684:CNC01590
uniprot id: Q5KKW8
names: Similarity
messages: Belongs to the Rab GDI family.

214684:CNA04100
gene id: 214684:CNA04100
uniprot id: Q5KP58
names: Similarity
messages: Belongs to the cytidylyltransferase family.

214684:CNB02880
gene id: 214684:CNB02880
uniprot id: Q5KM55
names: Subcellular Location Annotation
messages: Membrane

214684:CNE01430
gene id: 214684:CNE01430
uniprot id: Q5KH34
names: Similarity
messages: Belongs to the Cdt1 family.

214684:CNA04010
gene id: 214684:CNA04010
uniprot id: Q5KP67
names: Subcellular Location Annotation
messages: nuclear pore complex

214684:CNB05520
gene id: 214684:CNB05520
uniprot id: Q5KLE9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRP31 family.
messages: Nucleus

214684:CNB02030
gene id: 214684:CNB02030
uniprot id: Q5KME1
names: Similarity
messages: Belongs to the PPP phosphatase family.

214684:CNH01770
gene id: 214684:CNH01770
uniprot id: Q5KCP3
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS26 family.

214684:CNG00240
gene id: 214684:CNG00240
uniprot id: Q5KEK1
names: Similarity
messages: Belongs to the MYST (SAS/MOZ) family.

214684:CND05140
gene id: 214684:CND05140
uniprot id: Q5KHV9
names: Similarity
messages: Belongs to the actin family.

214684:CNB01090
gene id: 214684:CNB01090
uniprot id: Q5KMN3
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.

214684:CND03900
gene id: 214684:CND03900
uniprot id: Q5KI79
names: Similarity
messages: Belongs to the BZW family.

214684:CNI01130
gene id: 214684:CNI01130
uniprot id: Q5KBW5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SF3B1 family.
messages: Nucleus

214684:CND04190
gene id: 214684:CND04190
uniprot id: Q5KI52
names: Subcellular Location Annotation
messages: Membrane

214684:CNB03650
gene id: 214684:CNB03650
uniprot id: Q5KLY2
names: Cofactor
names: Similarity
messages: Belongs to the galactose-1-phosphate uridylyltransferase type 1 family.
messages: Binds 1 Fe cation per subunit.
messages: Binds 1 zinc ion per subunit.

214684:CNC03900
gene id: 214684:CNC03900
uniprot id: Q5KK85
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OXA1/ALB3/YidC family.
messages: Membrane

214684:CNL04190
gene id: 214684:CNL04190
uniprot id: Q5KDY8
names: Similarity
messages: Belongs to the HARBI1 family.

214684:CNA05090
gene id: 214684:CNA05090
uniprot id: Q5KNW3
names: Similarity
messages: Belongs to the eIF-2B gamma/epsilon subunits family.
messages: Belongs to the transferase hexapeptide repeat family.

214684:CNI01690
gene id: 214684:CNI01690
uniprot id: Q5KBR2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I NDUFA13 subunit family.
messages: Complex I functions in the transfer of electrons from NADH to the respiratory chain. Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis.
messages: Mitochondrion inner membrane

214684:CNA01250
gene id: 214684:CNA01250
uniprot id: Q5KPX1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Component of a multi-subunit COQ enzyme complex, composed of at least COQ3, COQ4, COQ5, COQ6, COQ7 and COQ9.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methyltransferase required for the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2).
messages: Mitochondrion inner membrane

214684:CNI03070
gene id: 214684:CNI03070
uniprot id: P0CS56
names: Function
names: Similarity
messages: Belongs to the WD repeat DDB2/WDR76 family.
messages: DNA-binding protein that binds to both single- and double-stranded DNA. Binds preferentially to UV-damaged DNA. May be involved in DNA-metabolic processes.

214684:CNJ02490
gene id: 214684:CNJ02490
uniprot id: P0CP82
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cyclophilin-type PPIase family. PPIase H subfamily.
messages: Nucleus
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides (By similarity).

214684:CNE02590
gene id: 214684:CNE02590
uniprot id: Q5KGR8
names: Similarity
messages: Belongs to the THADA family.

214684:CNF00910
gene id: 214684:CNF00910
uniprot id: P0CR78
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the STAM family.
messages: Component of the ESCRT-0 complex composed of HSE1 and VPS27.
messages: Component of the ESCRT-0 complex which is the sorting receptor for ubiquitinated cargo proteins at the multivesicular body (MVB).
messages: Endosome membrane

214684:CNC02920
gene id: 214684:CNC02920
uniprot id: P0CM12
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the anamorsin family.
messages: Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery required for the maturation of extramitochondrial Fe-S proteins. Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis, facilitating the de novo assembly of a [4Fe-4S] cluster on the scaffold complex CFD1-NBP35. Electrons are transferred to DRE2 from NADPH via the FAD- and FMN-containing protein TAH18. TAH18-DRE2 are also required for the assembly of the diferric tyrosyl radical cofactor of ribonucleotide reductase (RNR), probably by providing electrons for reduction during radical cofactor maturation in the catalytic small subunit RNR2.
messages: Cytoplasm
messages: Mitochondrion intermembrane space
messages: Monomer. Interacts with TAH18. Interacts with MIA40.
messages: The C-terminal domain binds 2 Fe-S clusters but is otherwise mostly in an intrinsically disordered conformation.
messages: The N-terminal domain has structural similarity with S-adenosyl-L-methionine-dependent methyltransferases, but does not bind S-adenosyl-L-methionine. It is required for correct assembly of the 2 Fe-S clusters.
messages: The twin Cx2C motifs are involved in the recognition by the mitochondrial MIA40-ERV1 disulfide relay system. The formation of 2 disulfide bonds in the Cx2C motifs through dithiol/disulfide exchange reactions effectively traps the protein in the mitochondrial intermembrane space.

214684:CNB04950
gene id: 214684:CNB04950
uniprot id: Q5KLK3
uniprot id: Q5KLK4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
messages: Membrane

214684:CNG03720
gene id: 214684:CNG03720
uniprot id: Q5KDJ7
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS8 family.

214684:CNN01720
gene id: 214684:CNN01720
uniprot id: Q5K6Z0
names: Similarity
messages: Belongs to the universal ribosomal protein uL22 family.

214684:CNA06350
gene id: 214684:CNA06350
uniprot id: Q5KNI7
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein P1/P2 family.

214684:CNF02250
gene id: 214684:CNF02250
uniprot id: Q5KFC2
uniprot id: Q5KFC3
names: Similarity
names: Subcellular Location Annotation
messages: In the C-terminal section; belongs to the NAGSA dehydrogenase family.
messages: In the N-terminal section; belongs to the acetylglutamate kinase family.
messages: Mitochondrion

214684:CNF00160
gene id: 214684:CNF00160
uniprot id: Q5KFY4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rho family. CDC42 subfamily.
messages: Cell membrane
messages: Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state.

214684:CNC01110
gene id: 214684:CNC01110
uniprot id: Q5KL15
names: Similarity
messages: Belongs to the nucleosome assembly protein (NAP) family.

214684:CNE02550
gene id: 214684:CNE02550
uniprot id: Q5KGS2
names: Similarity
messages: Belongs to the CDC73 family.

214684:CNC04890
gene id: 214684:CNC04890
uniprot id: Q5KJY8
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family.

214684:CNM01680
gene id: 214684:CNM01680
uniprot id: Q5K7Q0
names: Subcellular Location Annotation
messages: Membrane

214684:CNG02560
gene id: 214684:CNG02560
uniprot id: F5HFW5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. UDP-glucuronic acid decarboxylase subfamily.
messages: Golgi stack membrane
messages: Membrane

214684:CNG02780
gene id: 214684:CNG02780
uniprot id: Q5KDU2
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: COPI-coated vesicle membrane
messages: Cytoplasm
messages: Golgi apparatus membrane
messages: Membrane
messages: Oligomeric complex that consists of at least the alpha, beta, beta', gamma, delta, epsilon and zeta subunits.
messages: The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.

214684:CNC01520
gene id: 214684:CNC01520
uniprot id: P0CN32
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Mitochondrial GTPase that catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Mitochondrion

214684:CNL04880
gene id: 214684:CNL04880
uniprot id: Q5K8Q2
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

214684:CND00690
gene id: 214684:CND00690
uniprot id: Q5KJ47
names: Similarity
messages: Belongs to the MIX23 family.

214684:CNA02860
gene id: 214684:CNA02860
uniprot id: Q5KPG7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TUBGCP family.
messages: microtubule organizing center

214684:CNB00780
gene id: 214684:CNB00780
uniprot id: Q5KMR3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase delta/II small subunit family.
messages: Nucleus

214684:CNF01550
gene id: 214684:CNF01550
uniprot id: Q5KFJ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acts as component of the MCM2-7 complex (MCM complex) which is the replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity.
messages: Belongs to the MCM family.
messages: Nucleus

214684:CNM00900
gene id: 214684:CNM00900
uniprot id: Q5K7Y0
names: Similarity
messages: Belongs to the GMC oxidoreductase family.

214684:CNL03850
gene id: 214684:CNL03850
uniprot id: Q5K904
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the actin-binding proteins ADF family. GMF subfamily.
messages: Cytoplasm
messages: Nucleus

214684:CNJ00200
gene id: 214684:CNJ00200
uniprot id: P0CP90
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cyclophilin-type PPIase family. PPIL2 subfamily.
messages: May catalyze the cis-trans isomerization of proline imidic peptide bonds in oligopeptides thereby assisting the folding of proteins. May also function as a chaperone, playing a role in intracellular transport of proteins. May also have a protein ubiquitin ligase activity acting as an E3 ubiquitin protein ligase or as a ubiquitin-ubiquitin ligase promoting elongation of ubiquitin chains on proteins.
messages: Nucleus

214684:CNM00950
gene id: 214684:CNM00950
uniprot id: Q5K7X5
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.
messages: In eukaryotes there are cytoplasmic, mitochondrial and chloroplastic isozymes.

214684:CNG04180
gene id: 214684:CNG04180
uniprot id: Q5KDF5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SMC family. SMC2 subfamily.
messages: Nucleus

214684:CNK01590
gene id: 214684:CNK01590
uniprot id: P0CO94
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associated with the spliceosome.
messages: Belongs to the CEF1 family.
messages: Cytoplasm
messages: Involved in pre-mRNA splicing and cell cycle control.
messages: Nucleus

214684:CNI04030
gene id: 214684:CNI04030
uniprot id: Q5KB25
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UbiH/COQ6 family.
messages: Component of a multi-subunit COQ enzyme complex, composed of at least COQ3, COQ4, COQ5, COQ6, COQ7 and COQ9.
messages: FAD-dependent monooxygenase required for the C5-ring hydroxylation during ubiquinone biosynthesis. Catalyzes the hydroxylation of 3-polyprenyl-4-hydroxybenzoic acid to 3-polyprenyl-4,5-dihydroxybenzoic acid. The electrons required for the hydroxylation reaction may be funneled indirectly from NADPH via a ferredoxin/ferredoxin reductase system to COQ6.
messages: Mitochondrion inner membrane

214684:CNL04850
gene id: 214684:CNL04850
uniprot id: Q5K8Q5
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ERD2 family.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

214684:CNI00040
gene id: 214684:CNI00040
uniprot id: Q5KC69
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecY/SEC61-alpha family.
messages: Membrane

214684:CND03300
gene id: 214684:CND03300
uniprot id: Q5KIE0
names: Subcellular Location Annotation
messages: Nucleus

214684:CNK03370
gene id: 214684:CNK03370
uniprot id: Q5K935
names: Similarity
messages: Belongs to the universal ribosomal protein uL24 family.

214684:CNA08110
gene id: 214684:CNA08110
uniprot id: Q5KN13
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

214684:CNC05140
gene id: 214684:CNC05140
uniprot id: Q5KJW4
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

214684:CNA00460
gene id: 214684:CNA00460
uniprot id: Q5KQ49
names: Similarity
messages: Belongs to the TRAPPC13 family.

214684:CNF03880
gene id: 214684:CNF03880
uniprot id: Q5KEX5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Tim44 family.
messages: Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner.
messages: Mitochondrion inner membrane

214684:CNF03020
gene id: 214684:CNF03020
uniprot id: P0CP42
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OXR1 family.
messages: May be involved in protection from oxidative damage.
messages: Mitochondrion

214684:CNE00580
gene id: 214684:CNE00580
uniprot id: Q5KHB8
names: Similarity
messages: Belongs to the glutathione peroxidase family.

214684:CNA07860
gene id: 214684:CNA07860
uniprot id: P0CQ74
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: ATP-binding RNA helicase involved in translation initiation. Remodels RNA in response to ADP and ATP concentrations by facilitating disruption, but also formation of RNA duplexes (By similarity).
messages: Belongs to the DEAD box helicase family. DDX3/DED1 subfamily.
messages: Cytoplasm
messages: The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.

214684:CNE02740
gene id: 214684:CNE02740
uniprot id: Q5KGQ3
names: Similarity
messages: Belongs to the AB hydrolase superfamily. MetX family.

214684:CND05080
gene id: 214684:CND05080
uniprot id: Q5KHW4
names: Subcellular Location Annotation
messages: Membrane

214684:CNG00400
gene id: 214684:CNG00400
uniprot id: Q5KEI6
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 2 subfamily.

214684:CNA01750
gene id: 214684:CNA01750
uniprot id: P0CP04
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MOZART1 family.
messages: Part of the gamma-tubulin complex.
messages: Required for gamma-tubulin complex recruitment to the microtubule organizing center (MTOC).
messages: spindle pole body

214684:CNE00220
gene id: 214684:CNE00220
uniprot id: Q5KHF8
names: Similarity
messages: Belongs to the SWI5/SAE3 family.

214684:CNH02490
gene id: 214684:CNH02490
uniprot id: Q5KCW8
uniprot id: Q5KCW9
names: Similarity
messages: Belongs to the glycosyl hydrolase 5 (cellulase A) family.

214684:CNG00430
gene id: 214684:CNG00430
uniprot id: Q5KEI3
names: Similarity
messages: Belongs to the type-B carboxylesterase/lipase family.

214684:CNC00360
gene id: 214684:CNC00360
uniprot id: Q5KL88
names: Similarity
messages: Belongs to the PP2C family.

214684:CNI02040
gene id: 214684:CNI02040
uniprot id: Q5KBM7
names: Similarity
messages: Belongs to the DapA family.

214684:CNG01490
gene id: 214684:CNG01490
uniprot id: Q5KE74
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. Alanine aminotransferase subfamily.
messages: Homodimer.

214684:CNF04510
gene id: 214684:CNF04510
uniprot id: Q5KER8
names: Domain
names: Function
names: Similarity
messages: Belongs to the damage-control phosphatase family. Sugar phosphate phosphatase III subfamily.
messages: Metal-dependent phosphatase that shows phosphatase activity against several substrates, including fructose-1-phosphate and fructose-6-phosphate. Its preference for fructose-1-phosphate, a strong glycating agent that causes DNA damage rather than a canonical yeast metabolite, suggests a damage-control function in hexose phosphate metabolism.
messages: Subfamily III proteins have a conserved RTxK motif about 40-50 residues from the C-terminus; the threonine may be replaced by serine or cysteine.

214684:CNF03670
gene id: 214684:CNF03670
uniprot id: Q5KEZ4
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

214684:CND03040
gene id: 214684:CND03040
uniprot id: Q5KIG6
names: Similarity
messages: Belongs to the archaeal Rpo3/eukaryotic RPB3 RNA polymerase subunit family.

214684:CNA06500
gene id: 214684:CNA06500
uniprot id: Q5KNH2
names: Similarity
messages: Belongs to the universal ribosomal protein uS17 family.

214684:CNF00950
gene id: 214684:CNF00950
uniprot id: Q5KFQ4
names: Subcellular Location Annotation
messages: Nucleus

214684:CNN01350
gene id: 214684:CNN01350
uniprot id: Q5K726
names: Similarity
messages: Belongs to the peptidase S14 family.

214684:CNG04090
gene id: 214684:CNG04090
uniprot id: Q6U1Z4
names: Cofactor
names: Function
names: Subcellular Location Annotation
messages: Divalent metal cations. Mg(2+), Mn(2+) or Co(2+) can be used.
messages: Golgi apparatus membrane
messages: Responsible for addition of mannose residues in an alpha-1,3 linkage to a polymannosly precursor. May be involved in synthesis of capsule glucuronoxylomannan.

214684:CND01510
gene id: 214684:CND01510
uniprot id: Q5KIW5
names: Similarity
messages: Belongs to the ATP phosphoribosyltransferase family.

214684:CNE04620
gene id: 214684:CNE04620
uniprot id: Q5KG73
names: Similarity
messages: Belongs to the peptidase M16 family.

214684:CNH02750
gene id: 214684:CNH02750
uniprot id: Q5KCZ4
names: Function
names: Similarity
messages: Belongs to the phosphatase 2A regulatory subunit.
messages: The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment.

214684:CNH03830
gene id: 214684:CNH03830
uniprot id: Q5KDA3
names: Function
names: Similarity
messages: Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration.
messages: Belongs to the adaptor complexes large subunit family.

214684:CNC05890
gene id: 214684:CNC05890
uniprot id: Q5KJN6
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Peptidase M19 family.

214684:CNG03130
gene id: 214684:CNG03130
uniprot id: Q5KDQ7
names: Function
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

214684:CNC02380
gene id: 214684:CNC02380
uniprot id: Q5KKN8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the WD repeat PRP19 family.
messages: Homotetramer.
messages: Nucleus
messages: Ubiquitin-protein ligase which is mainly involved pre-mRNA splicing and DNA repair. Required for pre-mRNA splicing as component of the spliceosome.

214684:CNG00350
gene id: 214684:CNG00350
uniprot id: Q5KEJ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the archaeal/bacterial/fungal opsin family.
messages: Membrane

214684:CNF03740
gene id: 214684:CNF03740
uniprot id: Q5KEY7
names: Similarity
messages: Belongs to the PI3/PI4-kinase family.

214684:CNI03640
gene id: 214684:CNI03640
uniprot id: Q5KB64
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SDA1 family.
messages: Required for 60S pre-ribosomal subunits export to the cytoplasm.
messages: nucleolus

214684:CNF02410
gene id: 214684:CNF02410
uniprot id: Q5KFA6
names: Similarity
messages: Belongs to the RMD1/sif2 family.

214684:CNE05140
gene id: 214684:CNE05140
uniprot id: P0CO96
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SWC4 family.
messages: Component of the SWR1 chromatin-remodeling complex and of the NuA4 histone acetyltransferase complex.
messages: Component of the SWR1 complex which mediates the ATP-dependent exchange of histone H2A for the H2A variant HZT1 leading to transcriptional regulation of selected genes by chromatin remodeling. Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histone H4 and H2A. The NuA4 complex is also involved in DNA repair (By similarity).
messages: Nucleus

214684:CNA02450
gene id: 214684:CNA02450
uniprot id: Q5KPK7
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Homodimer.

214684:CNK01850
gene id: 214684:CNK01850
uniprot id: Q5K9I1
names: Subcellular Location Annotation
messages: Nucleus

214684:CNC05330
gene id: 214684:CNC05330
uniprot id: Q5KJU5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone H1/H5 family.
messages: Nucleus

214684:CNB01070
gene id: 214684:CNB01070
uniprot id: P0CS64
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPSF4/YTH1 family.
messages: Component of the cleavage factor I (CF I) involved in pre-mRNA 3'-end processing.
messages: Nucleus

214684:CNK02030
gene id: 214684:CNK02030
uniprot id: Q5K9G4
names: Subcellular Location Annotation
messages: Nucleus

214684:CNI02210
gene id: 214684:CNI02210
uniprot id: Q5KBK7
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

214684:CNE03360
gene id: 214684:CNE03360
uniprot id: Q5KGJ8
names: Similarity
messages: Belongs to the DNA/RNA non-specific endonuclease family.

214684:CNI00420
gene id: 214684:CNI00420
uniprot id: Q5KC33
names: Function
names: Similarity
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.

214684:CNG03450
gene id: 214684:CNG03450
uniprot id: Q5KDM4
names: Subcellular Location Annotation
messages: Nucleus

214684:CNA01330
gene id: 214684:CNA01330
uniprot id: Q5KPW4
names: Similarity
messages: Belongs to the actin family.

214684:CNF02630
gene id: 214684:CNF02630
uniprot id: Q5KF86
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

214684:CND01990
gene id: 214684:CND01990
uniprot id: P0CP28
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NPC2 family.
messages: Catalyzes the intermembrane transfer of phosphatidylglycerol and phosphatidylinositol.
messages: Monomer.

214684:CNJ01880
gene id: 214684:CNJ01880
uniprot id: Q5KAF6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

214684:CND03850
gene id: 214684:CND03850
uniprot id: Q5KI84
names: Similarity
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.

214684:CNI00100
gene id: 214684:CNI00100
uniprot id: Q5KC63
names: Subcellular Location Annotation
messages: Membrane

214684:CNB04930
gene id: 214684:CNB04930
uniprot id: Q5KLK6
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL43 family.

214684:CNA07220
gene id: 214684:CNA07220
uniprot id: Q5KNA0
names: Function
names: Similarity
messages: Belongs to the HisA/HisF family.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The glutaminase domain produces the ammonia necessary for the cyclase domain to produce IGP and AICAR from PRFAR. The ammonia is channeled to the active site of the cyclase domain.
messages: In the C-terminal section; belongs to the HisA/HisF family.

214684:CNC06390
gene id: 214684:CNC06390
uniprot id: Q5KJI9
names: Subcellular Location Annotation
messages: Membrane

214684:CND01490
gene id: 214684:CND01490
uniprot id: Q5KIW7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Cu-Zn superoxide dismutase family.
messages: Binds 1 copper ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

214684:CNG00830
gene id: 214684:CNG00830
uniprot id: Q5KEE1
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL36 family.

214684:CNG01150
gene id: 214684:CNG01150
uniprot id: Q5KEA8
names: Similarity
messages: Belongs to the spermidine/spermine synthase family.

214684:CNN01880
gene id: 214684:CNN01880
uniprot id: Q5K6X3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. NOG subfamily.
messages: Involved in the biogenesis of the 60S ribosomal subunit.
messages: nucleolus

214684:CNC04020
gene id: 214684:CNC04020
uniprot id: Q5KK73
names: Similarity
messages: Belongs to the methyltransferase superfamily. METTL16/RlmF family.

214684:CNL06560
gene id: 214684:CNL06560
uniprot id: Q5K889
names: Similarity
messages: Belongs to the syntaxin family.

214684:CNK00860
gene id: 214684:CNK00860
uniprot id: Q5K9T2
names: Subcellular Location Annotation
messages: Membrane

214684:CNC01370
gene id: 214684:CNC01370
uniprot id: Q5KKZ0
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family.

214684:CNI00150
gene id: 214684:CNI00150
uniprot id: Q5KC58
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SURF1 family.
messages: Mitochondrion inner membrane
messages: Probably involved in the biogenesis of the COX complex.

214684:CNA04770
gene id: 214684:CNA04770
uniprot id: Q5KNZ4
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class CDC14 subfamily.

214684:CNF04660
gene id: 214684:CNF04660
uniprot id: Q5KEQ3
names: Similarity
messages: Belongs to the carnitine/choline acetyltransferase family.

214684:CNH00140
gene id: 214684:CNH00140
uniprot id: Q5KC86
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rho family. CDC42 subfamily.
messages: Cell membrane
messages: Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state.

214684:CNH01060
gene id: 214684:CNH01060
uniprot id: Q5KCH7
names: Similarity
messages: Belongs to the protein kinase superfamily.

214684:CNI04080
gene id: 214684:CNI04080
uniprot id: Q5KB20
names: Similarity
messages: Belongs to the peptidase M28 family.

214684:CNN00680
gene id: 214684:CNN00680
uniprot id: Q5K790
names: Subcellular Location Annotation
messages: Membrane

214684:CNH03280
gene id: 214684:CNH03280
uniprot id: Q5KD48
names: Cofactor
names: Similarity
messages: Belongs to the isocitrate lyase/PEP mutase superfamily. Isocitrate lyase family.
messages: Can also use Mn(2+) ion.

214684:CNA02750
gene id: 214684:CNA02750
uniprot id: Q5KPH8
names: Similarity
messages: Belongs to the SGT family.

214684:CNJ02550
gene id: 214684:CNJ02550
uniprot id: Q5KA90
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

214684:CNC05660
gene id: 214684:CNC05660
uniprot id: Q5KJQ9
uniprot id: Q5KJR0
names: Function
names: Similarity
messages: Belongs to the phytoene/squalene synthase family.
messages: Catalyzes the condensation of 2 farnesyl pyrophosphate (FPP) moieties to form squalene.

214684:CNL06460
gene id: 214684:CNL06460
uniprot id: Q5K899
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

214684:CNE04140
gene id: 214684:CNE04140
uniprot id: Q5KGC2
names: Similarity
messages: Belongs to the Fmt family.

214684:CNI01160
gene id: 214684:CNI01160
uniprot id: P0CP46
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyadenylate-binding protein type-1 family.
messages: Binds the poly(A) tail of mRNA. Appears to be an important mediator of the multiple roles of the poly(A) tail in mRNA biogenesis, stability and translation. In the nucleus, involved in both mRNA cleavage and polyadenylation. Is also required for efficient mRNA export to the cytoplasm. Acts in concert with a poly(A)-specific nuclease (PAN) to affect poly(A) tail shortening, which may occur concomitantly with either nucleocytoplasmic mRNA transport or translational initiation. In the cytoplasm, stimulates translation initiation and regulates mRNA decay through translation termination-coupled poly(A) shortening, probably mediated by PAN (By similarity).
messages: Cytoplasm
messages: Nucleus

214684:CNH02200
gene id: 214684:CNH02200
uniprot id: Q5KCT7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COX17 family.
messages: Mitochondrion intermembrane space

214684:CNE03080
gene id: 214684:CNE03080
uniprot id: Q5KGM6
names: Similarity
messages: Belongs to the PAF1 family.

214684:CNC06920
gene id: 214684:CNC06920
uniprot id: A0A0S2LIH7
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

214684:CNA05800
gene id: 214684:CNA05800
uniprot id: Q5KNP4
names: Subcellular Location Annotation
messages: Membrane

214684:CNA00020
gene id: 214684:CNA00020
uniprot id: Q5KQ99
names: Similarity
messages: Belongs to the Cyclase 1 superfamily.

214684:CNA07920
gene id: 214684:CNA07920
uniprot id: Q5KN31
names: Subcellular Location Annotation
messages: Membrane

214684:CNL04800
gene id: 214684:CNL04800
uniprot id: P0CN92
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Adds the first Dol-P-Man derived mannose in an alpha-1,3 linkage to Man(5)GlcNAc(2)-PP-Dol.
messages: Belongs to the ALG3 family.
messages: Endoplasmic reticulum membrane

214684:CNA00150
gene id: 214684:CNA00150
uniprot id: Q5KQ86
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c-type heme lyase family.
messages: Lyase that catalyzes the covalent linking of the heme group to the cytochrome C apoprotein to produce the mature functional cytochrome.
messages: Membrane
messages: Mitochondrion inner membrane

214684:CNA03360
gene id: 214684:CNA03360
uniprot id: Q5KPC0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dynactin subunits 5/6 family. Dynactin subunit 5 subfamily.
messages: cytoskeleton

214684:CNA01020
gene id: 214684:CNA01020
uniprot id: Q5KPZ5
names: Subcellular Location Annotation
messages: Nucleus

214684:CNB03930
gene id: 214684:CNB03930
uniprot id: Q5KLV5
names: Similarity
messages: Belongs to the AAA ATPase family.

214684:CND02520
gene id: 214684:CND02520
uniprot id: Q5KIL6
names: Similarity
messages: Belongs to the terpene cyclase/mutase family.

214684:CND02660
gene id: 214684:CND02660
uniprot id: Q5KIK2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRP40 family.
messages: Cytoplasm
messages: nucleolus

214684:CNN00080
gene id: 214684:CNN00080
uniprot id: P0CP20
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Adds a myristoyl group to the N-terminal glycine residue of certain cellular proteins.
messages: Belongs to the NMT family.
messages: Cytoplasm
messages: Monomer.

214684:CNF04490
gene id: 214684:CNF04490
uniprot id: Q5KES0
names: Similarity
messages: Belongs to the protein kinase superfamily.

214684:CNI03480
gene id: 214684:CNI03480
uniprot id: Q5KB78
names: Similarity
messages: Belongs to the shaker potassium channel beta subunit family.

214684:CNI01660
gene id: 214684:CNI01660
uniprot id: Q5KBR5
uniprot id: Q5KBR6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTF2H2 family.
messages: Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to TFIIK, in RNA transcription by RNA polymerase II.
messages: Nucleus

214684:CND04600
gene id: 214684:CND04600
uniprot id: Q5KI10
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

214684:CNE01960
gene id: 214684:CNE01960
uniprot id: Q5KGY0
names: Similarity
messages: Belongs to the universal ribosomal protein uL2 family.

214684:CNA03970
gene id: 214684:CNA03970
uniprot id: Q5KP72
names: Similarity
messages: Belongs to the PPP phosphatase family.

214684:CNF00290
gene id: 214684:CNF00290
uniprot id: Q5KFX1
names: Similarity
messages: Belongs to the GDA1/CD39 NTPase family.

214684:CNA07090
gene id: 214684:CNA07090
uniprot id: Q5KNB3
names: Subcellular Location Annotation
messages: Membrane

214684:CND00660
gene id: 214684:CND00660
uniprot id: Q5KJ50
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase group 1 family.
messages: Endoplasmic reticulum membrane
messages: Mannosylates Man(2)GlcNAc(2)-dolichol diphosphate and Man(1)GlcNAc(2)-dolichol diphosphate to form Man(3)GlcNAc(2)-dolichol diphosphate.

214684:CNA04310
gene id: 214684:CNA04310
uniprot id: Q5KP37
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Homodimer.

214684:CNK02780
gene id: 214684:CNK02780
uniprot id: Q5K991
names: Similarity
messages: Belongs to the eukaryotic initiation factor 4E family.

214684:CNN00840
gene id: 214684:CNN00840
uniprot id: Q5K775
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IWR1/SLC7A6OS family.
messages: Cytoplasm
messages: Directs RNA polymerase II nuclear import.
messages: Nucleus

214684:CNG01650
gene id: 214684:CNG01650
uniprot id: Q5KE58
names: Similarity
messages: Belongs to the DEAD box helicase family. DDX41 subfamily.

214684:CNL05310
gene id: 214684:CNL05310
uniprot id: Q5K8K8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MICOS complex subunit Mic60 family.
messages: Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane. Plays a role in keeping cristae membranes connected to the inner boundary membrane. Also promotes protein import via the mitochondrial intermembrane space assembly (MIA) pathway.
messages: Component of the mitochondrial contact site and cristae organizing system (MICOS) complex.
messages: Membrane
messages: Mitochondrion inner membrane

214684:CNB04320
gene id: 214684:CNB04320
uniprot id: Q5KLR6
names: Similarity
messages: Belongs to the PPP4R2 family.

214684:CNJ02210
gene id: 214684:CNJ02210
uniprot id: Q5KAC4
names: Subcellular Location Annotation
messages: Membrane

214684:CNA01380
gene id: 214684:CNA01380
uniprot id: Q5KPV9
names: Similarity
messages: Belongs to the peptidase S8 family.

214684:CNG02610
gene id: 214684:CNG02610
uniprot id: Q5KDW0
names: Similarity
messages: Belongs to the adaptor complexes medium subunit family.

214684:CNC01820
gene id: 214684:CNC01820
uniprot id: Q5KKU4
names: Similarity
messages: Belongs to the AccD/PCCB family.

214684:CNC06470
gene id: 214684:CNC06470
uniprot id: Q5KJI1
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.

214684:CNE00270
gene id: 214684:CNE00270
uniprot id: Q5KHF3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. YAT (TC 2.A.3.10) family.
messages: Membrane

214684:CND05850
gene id: 214684:CND05850
uniprot id: Q5KHN6
names: Similarity
messages: Belongs to the DNA polymerase type-B-like family.

214684:CND05770
gene id: 214684:CND05770
uniprot id: P0CN60
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ETF alpha-subunit/FixB family.
messages: Binds 1 FAD per dimer.
messages: Heterodimer of an alpha and a beta subunit.
messages: Mitochondrion matrix
messages: The electron transfer flavoprotein serves as a specific electron acceptor for several dehydrogenases, including five acyl-CoA dehydrogenases, glutaryl-CoA and sarcosine dehydrogenase. It transfers the electrons to the main mitochondrial respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase) (By similarity).

214684:CNF04760
gene id: 214684:CNF04760
uniprot id: Q5KEP3
names: Similarity
messages: Belongs to the amino acid/polyamine transporter 2 family.

214684:CNJ01650
gene id: 214684:CNJ01650
uniprot id: Q5KAH7
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M36 family.
messages: Binds 1 zinc ion per subunit.
messages: Secreted

214684:CNA06430
gene id: 214684:CNA06430
uniprot id: Q5KNH9
names: Similarity
messages: Belongs to the PAT1 family.

214684:CNC04350
gene id: 214684:CNC04350
uniprot id: Q5KK40
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GcvT family.
messages: Mitochondrion
messages: The glycine cleavage system catalyzes the degradation of glycine.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

214684:CNC06530
gene id: 214684:CNC06530
uniprot id: Q5KJH5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

214684:CNE04550
gene id: 214684:CNE04550
uniprot id: Q5KG79
names: Similarity
messages: Belongs to the glycosyl hydrolase 47 family.

214684:CNL05340
gene id: 214684:CNL05340
uniprot id: P0CN10
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the deoxyhypusine hydroxylase family.
messages: Binds 2 Fe(2+) ions per subunit.
messages: Catalyzes the hydroxylation of the N(6)-(4-aminobutyl)-L-lysine intermediate to form hypusine, an essential post-translational modification only found in mature eIF-5A factor.
messages: Cytoplasm
messages: Nucleus

214684:CNE04710
gene id: 214684:CNE04710
uniprot id: Q5KG64
names: Subcellular Location Annotation
messages: Nucleus

214684:CNK00970
gene id: 214684:CNK00970
uniprot id: Q5K9S1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptobrevin family.
messages: Cell membrane
messages: Membrane

214684:CNN02420
gene id: 214684:CNN02420
uniprot id: Q5K6S8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

214684:CNG02670
gene id: 214684:CNG02670
uniprot id: Q5KDV3
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. HMG-CoA synthase family.
messages: Catalyzes the condensation of acetyl-CoA with acetoacetyl-CoA to form HMG-CoA.

214684:CNK02730
gene id: 214684:CNK02730
uniprot id: Q5K996
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

214684:CNH02110
gene id: 214684:CNH02110
uniprot id: Q5KCS8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone deacetylase family. HD Type 1 subfamily.
messages: Nucleus

214684:CNB04820
gene id: 214684:CNB04820
uniprot id: Q5KLL7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MEF2 family.
messages: Nucleus

214684:CNL06410
gene id: 214684:CNL06410
uniprot id: Q5K8A3
names: Subcellular Location Annotation
messages: Membrane

214684:CNA06640
gene id: 214684:CNA06640
uniprot id: P0CQ88
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent RNA helicase involved in mRNA splicing. May destabilize the U1/5'-splice site duplex to permit an effective competition for the 5'-splice site by the U6 snRNA, resulting in the switch between U1 and U6 at the 5'-splice site. May also act to unwind the U4/U6 base-pairing interaction in the U4/U6/U5 snRNP, facilitating the first covalent step of splicing (By similarity).
messages: Belongs to the DEAD box helicase family. DDX23/PRP28 subfamily.
messages: Component of the U5 snRNP complex.
messages: Cytoplasm
messages: Nucleus
messages: The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.

214684:CNC02210
gene id: 214684:CNC02210
uniprot id: Q5KKQ4
names: Similarity
messages: Belongs to the CNOT9 family.

214684:CNG00610
gene id: 214684:CNG00610
uniprot id: Q5KEG3
names: Similarity
messages: Belongs to the PI3/PI4-kinase family. Type III PI4K subfamily.

214684:CNE01310
gene id: 214684:CNE01310
uniprot id: P0CO08
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associated with the spliceosome.
messages: Belongs to the crooked-neck family.
messages: Involved in pre-mRNA splicing and cell cycle progression.
messages: Nucleus

214684:CNA04610
gene id: 214684:CNA04610
uniprot id: Q5KP10
names: Similarity
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.
messages: Octamer of two non-identical subunits IDH1 and IDH2.

214684:CNA05860
gene id: 214684:CNA05860
uniprot id: P0CO46
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PNO1 family.
messages: Component of the small ribosomal subunit, ribosomal RNA processing complex (SSU RRP complex).
messages: Cytoplasm
messages: Required for small ribosomal subunit (SSU) synthesis. Has a role in the processing of early nucleolar and late cytoplasmic pre-RNA species (By similarity).
messages: nucleolus

214684:CNK02900
gene id: 214684:CNK02900
uniprot id: Q5K979
names: Similarity
messages: Belongs to the universal ribosomal protein uS8 family.

214684:CNA03010
gene id: 214684:CNA03010
uniprot id: Q5KPF2
names: Similarity
messages: Belongs to the HARBI1 family.

214684:CNJ02040
gene id: 214684:CNJ02040
uniprot id: Q5KAD9
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

214684:CNA00180
gene id: 214684:CNA00180
uniprot id: Q5KQ80
uniprot id: Q5KQ81
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family.
messages: Membrane

214684:CNJ00070
gene id: 214684:CNJ00070
uniprot id: Q5KAY0
names: Subcellular Location Annotation
messages: Membrane

214684:CNA01820
gene id: 214684:CNA01820
uniprot id: Q5KPR4
names: Subcellular Location Annotation
messages: Nucleus

214684:CNJ01210
gene id: 214684:CNJ01210
uniprot id: Q5KAM1
names: Similarity
messages: Belongs to the FAH family.

214684:CNF02840
gene id: 214684:CNF02840
uniprot id: Q5KF65
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone deacetylase family. HD Type 1 subfamily.
messages: Nucleus

214684:CNA05420
gene id: 214684:CNA05420
uniprot id: Q5KNT0
names: Similarity
messages: Belongs to the V-ATPase E subunit family.

214684:CND03190
gene id: 214684:CND03190
uniprot id: Q5KIF1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily.
messages: Membrane

214684:CNB03800
gene id: 214684:CNB03800
uniprot id: Q5KLW6
names: Similarity
messages: Belongs to the GroES chaperonin family.

214684:CNE05050
gene id: 214684:CNE05050
uniprot id: Q5KG31
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDC42SE/SPEC family.
messages: Cell membrane
messages: Membrane
messages: Nucleus
messages: cytoskeleton

214684:CNI02240
gene id: 214684:CNI02240
uniprot id: Q5KBK4
names: Similarity
messages: Belongs to the DODA-type extradiol aromatic ring-opening dioxygenase family.

214684:CNJ01750
gene id: 214684:CNJ01750
uniprot id: Q5KAG8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the mannose-6-phosphate isomerase type 1 family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in the synthesis of the GDP-mannose and dolichol-phosphate-mannose required for a number of critical mannosyl transfer reactions.

214684:CNF02990
gene id: 214684:CNF02990
uniprot id: Q5KF49
names: Subcellular Location Annotation
messages: Membrane

214684:CND04160
gene id: 214684:CND04160
uniprot id: Q5KI55
names: Similarity
messages: Belongs to the RRN3 family.

214684:CNA07530
gene id: 214684:CNA07530
uniprot id: Q5KN69
names: Subcellular Location Annotation
messages: nucleolus

214684:CNM01760
gene id: 214684:CNM01760
uniprot id: Q5K7P1
names: Function
names: Similarity
messages: Acts as a regulatory subunit of the 26S proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins.
messages: Belongs to the proteasome subunit S1 family.

214684:CNF03200
gene id: 214684:CNF03200
uniprot id: Q5KF38
names: Similarity
messages: Belongs to the phosphatase 2A regulatory subunit B family.

214684:CNG04190
gene id: 214684:CNG04190
uniprot id: Q5KDF4
names: Subcellular Location Annotation
messages: Membrane

214684:CNI02890
gene id: 214684:CNI02890
uniprot id: P0CO62
names: Function
names: Similarity
messages: Belongs to the AB hydrolase superfamily.
messages: Demethylates proteins that have been reversibly carboxymethylated. Demethylates the phosphatase PP2A catalytic subunit (By similarity).

214684:CNG03510
gene id: 214684:CNG03510
uniprot id: Q5KDL7
names: Subcellular Location Annotation
messages: Nucleus

214684:CNM01850
gene id: 214684:CNM01850
uniprot id: Q5K7N2
names: Similarity
messages: Belongs to the CCDC43 family.

214684:CNF01620
gene id: 214684:CNF01620
uniprot id: P0CS02
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TPT transporter family. SLC35D subfamily.
messages: Cytoplasmic vesicle membrane
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Homooligomer.
messages: Involved in the import of GDP-mannose from the cytoplasm into the Golgi lumen. Involved in capsule synthesis.

214684:CNI00630
gene id: 214684:CNI00630
uniprot id: Q5KC16
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the U1 small nuclear ribonucleoprotein C family.
messages: Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing. The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA. Stimulates commitment or early (E) complex formation by stabilizing the base pairing of the 5' end of the U1 snRNA and the 5' splice-site region.
messages: Nucleus
messages: U1 snRNP is composed of the 7 core Sm proteins B/B', D1, D2, D3, E, F and G that assemble in a heptameric protein ring on the Sm site of the small nuclear RNA to form the core snRNP, and at least 3 U1 snRNP-specific proteins U1-70K, U1-A and U1-C. U1-C interacts with U1 snRNA and the 5' splice-site region of the pre-mRNA.

214684:CNA03300
gene id: 214684:CNA03300
uniprot id: Q5KPC6
names: Similarity
messages: Belongs to the glycosyl hydrolase 5 (cellulase A) family.

214684:CNF03560
gene id: 214684:CNF03560
uniprot id: Q5KF04
names: Similarity
messages: Belongs to the UQCRH/QCR6 family.

214684:CNF01700
gene id: 214684:CNF01700
uniprot id: Q5KFH8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferrochelatase family.
messages: Catalyzes the ferrous insertion into protoporphyrin IX.
messages: Mitochondrion inner membrane

214684:CNG01130
gene id: 214684:CNG01130
uniprot id: Q5KEB0
names: Similarity
messages: Belongs to the glycosyltransferase 47 family.

214684:CNF01960
gene id: 214684:CNF01960
uniprot id: P0CO86
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MRG family.
messages: Component of the NuA4 histone acetyltransferase complex.
messages: Involved in deacetylation of histones, chromatin assembly and chromosome segregation. May act as a transcriptional oscillator, directing histone deacetylases to specific chromosomal domains. Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histone H4 and H2A. The NuA4 complex is also involved in DNA repair (By similarity).
messages: Nucleus

214684:CNF01650
gene id: 214684:CNF01650
uniprot id: Q5KFI3
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS10 family.

214684:CNE04990
gene id: 214684:CNE04990
uniprot id: Q5KG37
names: Subcellular Location Annotation
messages: Membrane

214684:CND04950
gene id: 214684:CND04950
uniprot id: Q5KHX7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in the mitochondria. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Mitochondrion
messages: Subunit of the heterotrimeric GatCAB amidotransferase (AdT) complex, composed of A, B and C subunits.

214684:CNA00070
gene id: 214684:CNA00070
uniprot id: Q5KQ94
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prohibitin family.
messages: Mitochondrion inner membrane

214684:CNI01190
gene id: 214684:CNI01190
uniprot id: Q5KBV9
names: Subcellular Location Annotation
messages: Nucleus

214684:CNJ02430
gene id: 214684:CNJ02430
uniprot id: Q5KAA2
names: Subcellular Location Annotation
messages: Membrane

214684:CNB05380
gene id: 214684:CNB05380
uniprot id: Q5KLG3
names: Similarity
messages: Belongs to the SUI1 family.

214684:CNG04320
gene id: 214684:CNG04320
uniprot id: Q5KDE0
names: Cofactor
names: Similarity
messages: Belongs to the sirtuin family. Class I subfamily.
messages: Binds 1 zinc ion per subunit.

214684:CND02390
gene id: 214684:CND02390
uniprot id: Q5KIM9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane magnesium transporter (TC 1.A.67) family.
messages: Membrane

214684:CNJ00220
gene id: 214684:CNJ00220
uniprot id: Q5KAW6
names: Domain
names: Function
names: Similarity
messages: Belongs to the DEAD box helicase family.
messages: RNA helicase.
messages: The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.

214684:CNK02310
gene id: 214684:CNK02310
uniprot id: Q5K9D7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 independent methionine synthase family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine resulting in methionine formation.

214684:CNK00370
gene id: 214684:CNK00370
uniprot id: Q5K9X5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. EFM4 family.
messages: Cytoplasm
messages: S-adenosyl-L-methionine-dependent protein-lysine N-methyltransferase that mono- and dimethylates elongation factor 1-alpha at 'Lys-316'. May play a role in intracellular transport.

214684:CNF04020
gene id: 214684:CNF04020
uniprot id: Q5KEW3
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

214684:CNM00720
gene id: 214684:CNM00720
uniprot id: Q5K7Z7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COX15/CtaA family.
messages: Membrane

214684:CNG01640
gene id: 214684:CNG01640
uniprot id: Q5KE59
names: Similarity
messages: Belongs to the peptidase M20A family.

214684:CNA07810
gene id: 214684:CNA07810
uniprot id: Q5KN41
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GTR/RAG GTP-binding protein family.
messages: Component of the GSE complex.
messages: GTPase involved in activation of the TORC1 signaling pathway, which promotes growth and represses autophagy in nutrient-rich conditions.

214684:CNC05760
gene id: 214684:CNC05760
uniprot id: Q5KJP9
names: Similarity
messages: Belongs to the peptidase S10 family.

214684:CNB04430
gene id: 214684:CNB04430
uniprot id: Q5KLQ6
names: Subcellular Location Annotation
messages: Membrane

214684:CND03230
gene id: 214684:CND03230
uniprot id: Q5KIE7
names: Similarity
messages: Belongs to the nucleoporin NSP1/NUP62 family.

214684:CNB01460
gene id: 214684:CNB01460
uniprot id: Q5KMJ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

214684:CNE00660
gene id: 214684:CNE00660
uniprot id: Q5KHB0
names: Similarity
messages: Belongs to the peptidase S10 family.

214684:CNK01450
gene id: 214684:CNK01450
uniprot id: Q5K9M5
names: Subcellular Location Annotation
messages: Cytoplasm

214684:CNF02960
gene id: 214684:CNF02960
uniprot id: Q5KF52
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetate uptake transporter (AceTr) (TC 2.A.96) family.
messages: Membrane

214684:CNK02760
gene id: 214684:CNK02760
uniprot id: Q5K993
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

214684:CNC00060
gene id: 214684:CNC00060
uniprot id: Q5KLB7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

214684:CNE02730
gene id: 214684:CNE02730
uniprot id: Q5KGQ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

214684:CNA07060
gene id: 214684:CNA07060
uniprot id: Q5KNB6
names: Subcellular Location Annotation
messages: Membrane

214684:CNC03240
gene id: 214684:CNC03240
uniprot id: Q5KKE9
names: Function
names: Similarity
messages: Belongs to the VPS35 family.
messages: Plays a role in vesicular protein sorting.

214684:CNE01050
gene id: 214684:CNE01050
uniprot id: Q5KH70
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAF1 family.
messages: Nucleus

214684:CND04050
gene id: 214684:CND04050
uniprot id: Q5KI66
names: Similarity
messages: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. Aurora subfamily.

214684:CNG01900
gene id: 214684:CNG01900
uniprot id: Q5KE33
names: Similarity
messages: Belongs to the NifU family.

214684:CNJ01730
gene id: 214684:CNJ01730
uniprot id: Q5KAH0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the eukaryotic-type primase large subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments made during discontinuous DNA replication.

214684:CNB01920
gene id: 214684:CNB01920
uniprot id: Q5KMF2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the oxidase-dependent Fe transporter (OFeT) (TC 9.A.10.1) family.
messages: Membrane

214684:CNI02560
gene id: 214684:CNI02560
uniprot id: Q5KBH0
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

214684:CNH00180
gene id: 214684:CNH00180
uniprot id: Q5KC90
names: Subcellular Location Annotation
messages: Membrane

214684:CNA02580
gene id: 214684:CNA02580
uniprot id: Q5KPJ4
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

214684:CNF02900
gene id: 214684:CNF02900
uniprot id: Q5KF58
names: Subcellular Location Annotation
messages: Nucleus

214684:CND06300
gene id: 214684:CND06300
uniprot id: Q5KHJ1
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 2 subfamily.

214684:CNC00270
gene id: 214684:CNC00270
uniprot id: Q5KL96
names: Subcellular Location Annotation
messages: Membrane

214684:CNE01170
gene id: 214684:CNE01170
uniprot id: Q5KH58
names: Similarity
messages: Belongs to the heat shock protein 90 family.

214684:CND00440
gene id: 214684:CND00440
uniprot id: Q5KJ69
names: Subcellular Location Annotation
messages: Membrane

214684:CNA01850
gene id: 214684:CNA01850
uniprot id: Q5KPR1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the iron-containing alcohol dehydrogenase family. Hydroxyacid-oxoacid transhydrogenase subfamily.
messages: Mitochondrion

214684:CNF02560
gene id: 214684:CNF02560
uniprot id: Q5KF93
names: Subcellular Location Annotation
messages: Membrane

214684:CNB04190
gene id: 214684:CNB04190
uniprot id: Q5KLS9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Tom40 family.
messages: Membrane
messages: Mitochondrion outer membrane

214684:CNK00740
gene id: 214684:CNK00740
uniprot id: Q5K9U5
names: Function
messages: Catalytic subunit of an S-adenosyl-L-methionine-dependent tRNA methyltransferase complex that mediates the methylation of the guanosine nucleotide at position 10 (m2G10) in tRNAs.

214684:CNE04260
gene id: 214684:CNE04260
uniprot id: P0CM76
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Clp1 family. Clp1 subfamily.
messages: Component of a pre-mRNA cleavage factor complex. Interacts directly with PCF11.
messages: May lack the polyribonucleotide 5'-hydroxyl-kinase and polynucleotide 5'-hydroxyl-kinase activities that are characteristic of the human ortholog.
messages: Nucleus
messages: Required for endonucleolytic cleavage during polyadenylation-dependent pre-mRNA 3'-end formation.

214684:CNE01130
gene id: 214684:CNE01130
uniprot id: Q5KH62
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of GlcNAc-6-P into GlcNAc-1-P during the synthesis of uridine diphosphate/UDP-GlcNAc, which is a biosynthetic precursor of chitin and also supplies the amino sugars for N-linked oligosaccharides of glycoproteins.

214684:CNE01830
gene id: 214684:CNE01830
uniprot id: Q5KGZ3
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

214684:CNI03040
gene id: 214684:CNI03040
uniprot id: Q5KBC3
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

214684:CNL06590
gene id: 214684:CNL06590
uniprot id: Q5K886
names: Subcellular Location Annotation
messages: Membrane