211586:SO RS19445
gene id: 211586:SO_RS19445
uniprot id: Q8E9R6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiJ family.
messages: Cytoplasm
messages: Required for ubiquinone (coenzyme Q) biosynthesis. Binds hydrophobic ubiquinone biosynthetic intermediates via its SCP2 domain and is essential for the stability of the Ubi complex. May constitute a docking platform where Ubi enzymes assemble and access their SCP2-bound polyprenyl substrates.

211586:SO RS14435
gene id: 211586:SO_RS14435
uniprot id: Q8ECM5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Cell inner membrane
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

211586:SO RS10040
gene id: 211586:SO_RS10040
uniprot id: Q8EF17
names: Similarity
messages: Belongs to the GppA/Ppx family.

211586:SO RS15110
gene id: 211586:SO_RS15110
uniprot id: Q8ECA5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

211586:SO RS01210
gene id: 211586:SO_RS01210
uniprot id: Q8EK48
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

211586:SO RS17285
gene id: 211586:SO_RS17285
uniprot id: Q8EB29
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family.
messages: Membrane

211586:SO RS02290
gene id: 211586:SO_RS02290
uniprot id: Q8EJI6
names: Cofactor
names: Disruption Phenotype
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the multiheme cytochrome c family.
messages: Binds 8 heme c groups covalently per monomer.
messages: Exposure to oxygen reduces copper binding and leads to the formation of a disulfide bond between the two Cys residues that bind the copper ion.
messages: Homotrimer.
messages: Loss of growth based on sulfite respiration.
messages: Periplasm
messages: Respiratory sulfite reductase that catalyzes the reduction of sulfite to sulfide in a single step, consuming six electrons in the process. Required for sulfite respiration under anaerobic growth conditions. Does not contribute to nitrite reduction.
messages: The eighth heme binding site has an unusual CXXXXXCH motif.

211586:SO RS21810
gene id: 211586:SO_RS21810
uniprot id: Q8E8H2
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

211586:SO RS16550
gene id: 211586:SO_RS16550
uniprot id: Q8EBH4
names: Similarity
messages: Belongs to the XFP family.

211586:SO RS22730
gene id: 211586:SO_RS22730
uniprot id: Q8E823
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

211586:SO RS21045
gene id: 211586:SO_RS21045
uniprot id: Q8E8X2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S-adenosyl-L-methionine to the 2'-OH of the wobble nucleotide.

211586:SO RS02420
gene id: 211586:SO_RS02420
uniprot id: Q8EJG1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UbiD family.
messages: Binds 1 prenylated FMN (prenyl-FMN) per subunit.
messages: Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis.
messages: Cell membrane
messages: Homohexamer.

211586:SO RS06040
gene id: 211586:SO_RS06040
uniprot id: Q8EHC7
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

211586:SO RS03670
gene id: 211586:SO_RS03670
uniprot id: Q8EIQ9
names: Similarity
messages: Belongs to the UbiH/COQ6 family.

211586:SO RS21715
gene id: 211586:SO_RS21715
uniprot id: Q8E8J2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GlpE family.
messages: Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide.
messages: Cytoplasm

211586:SO RS04915
gene id: 211586:SO_RS04915
uniprot id: Q8EHZ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

211586:SO RS01005
gene id: 211586:SO_RS01005
uniprot id: Q8EK83
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic pantothenate kinase family.
messages: Cytoplasm

211586:SO RS07870
gene id: 211586:SO_RS07870
uniprot id: Q8EG98
names: Similarity
messages: Belongs to the acetyl-CoA hydrolase/transferase family.

211586:SO RS15145
gene id: 211586:SO_RS15145
uniprot id: Q8EC99
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.

211586:SO RS03955
gene id: 211586:SO_RS03955
uniprot id: Q8EIJ6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

211586:SO RS11785
gene id: 211586:SO_RS11785
uniprot id: Q8EE31
names: Function
names: Subunit
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease.

211586:SO RS14630
gene id: 211586:SO_RS14630
uniprot id: Q8ECK0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidine kinase family.
messages: Cytoplasm
messages: Homotetramer.

211586:SO RS05475
gene id: 211586:SO_RS05475
uniprot id: Q8EHN4
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

211586:SO RS18875
gene id: 211586:SO_RS18875
uniprot id: Q8EA43
names: Similarity
messages: Belongs to the SAICAR synthetase family.

211586:SO RS12780
gene id: 211586:SO_RS12780
uniprot id: Q8EDI9
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
messages: Allosterically activated by GTP.
messages: Belongs to the UPRTase family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.
messages: Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.

211586:SO RS18470
gene id: 211586:SO_RS18470
uniprot id: Q8EAD9
names: Similarity
messages: Belongs to the bacterial solute-binding protein ModA family.

211586:SO RS02080
gene id: 211586:SO_RS02080
uniprot id: Q8EJN1
names: Cofactor
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.
messages: Binds 1 [4Fe-4S] cluster per subunit.

211586:SO RS18325
gene id: 211586:SO_RS18325
uniprot id: Q8EAG5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

211586:SO RS22085
gene id: 211586:SO_RS22085
uniprot id: Q8E8B8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

211586:SO RS22930
gene id: 211586:SO_RS22930
uniprot id: Q8CME3
names: Similarity
messages: Belongs to the site-specific recombinase resolvase family.

211586:SO RS11170
gene id: 211586:SO_RS11170
uniprot id: Q8EEE6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. CmoB family.
messages: Catalyzes carboxymethyl transfer from carboxy-S-adenosyl-L-methionine (Cx-SAM) to 5-hydroxyuridine (ho5U) to form 5-carboxymethoxyuridine (cmo5U) at position 34 in tRNAs.
messages: Homotetramer.

211586:SO RS09315
gene id: 211586:SO_RS09315
uniprot id: Q8EFF3
names: Function
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.
messages: Catalyzes the phosphorylation of guanosine and inosine to GMP and IMP, respectively.

211586:SO RS14200
gene id: 211586:SO_RS14200
uniprot id: Q8ECS1
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the type IA topoisomerase family.
messages: Binds two Mg(2+) per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

211586:SO RS17825
gene id: 211586:SO_RS17825
uniprot id: Q8EAR9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KdsA family.
messages: Cytoplasm

211586:SO RS09020
gene id: 211586:SO_RS09020
uniprot id: Q8EFL9
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the gamma-glutamyltransferase family.
messages: Cleaved by autocatalysis into a large and a small subunit.
messages: This enzyme consists of two polypeptide chains, which are synthesized in precursor form from a single polypeptide.

211586:SO RS01835
gene id: 211586:SO_RS01835
uniprot id: Q8EJS9
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

211586:SO RS08330
gene id: 211586:SO_RS08330
uniprot id: Q8EG02
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family. L-methionine gamma-lyase subfamily.

211586:SO RS16340
gene id: 211586:SO_RS16340
uniprot id: Q8EBL5
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

211586:SO RS15600
gene id: 211586:SO_RS15600
uniprot id: Q8EBZ9
names: Similarity
messages: Belongs to the UPF0301 (AlgH) family.

211586:SO RS17775
gene id: 211586:SO_RS17775
uniprot id: Q8EAS5
names: Function
names: Similarity
messages: Belongs to the ketopantoate reductase family.
messages: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.

211586:SO RS19860
gene id: 211586:SO_RS19860
uniprot id: Q8E9J3
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

211586:SO RS05605
gene id: 211586:SO_RS05605
uniprot id: Q8EHL6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

211586:SO RS08610
gene id: 211586:SO_RS08610
uniprot id: Q8EFV2
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

211586:SO RS13555
gene id: 211586:SO_RS13555
uniprot id: Q8ED47
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate:Na(+) symporter (ESS) (TC 2.A.27) family.
messages: Catalyzes the sodium-dependent transport of glutamate.
messages: Cell inner membrane

211586:SO RS17035
gene id: 211586:SO_RS17035
uniprot id: Q8EB83
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

211586:SO RS16955
gene id: 211586:SO_RS16955
uniprot id: Q8EBA1
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

211586:SO RS10035
gene id: 211586:SO_RS10035
uniprot id: Q8EF19
names: Similarity
messages: Belongs to the YkuD family.

211586:SO RS19560
gene id: 211586:SO_RS19560
uniprot id: Q8CX35
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell inner membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).

211586:SO RS10955
gene id: 211586:SO_RS10955
uniprot id: Q8EEJ2
names: Subcellular Location Annotation
messages: Membrane

211586:SO RS10785
gene id: 211586:SO_RS10785
uniprot id: Q8EEM7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gluconeogenesis factor family.
messages: Cytoplasm
messages: Required for morphogenesis under gluconeogenic growth conditions.

211586:SO RS00760
gene id: 211586:SO_RS00760
uniprot id: Q8EKD0
names: Similarity
messages: Belongs to the GSP C family.

211586:SO RS07765
gene id: 211586:SO_RS07765
uniprot id: Q8EGC2
names: Similarity
messages: Belongs to the HIBADH-related family.

211586:SO RS12145
gene id: 211586:SO_RS12145
uniprot id: Q8EDV8
names: Function
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
messages: Catalyzes two reactions in de novo purine nucleotide biosynthesis. Catalyzes the breakdown of 5-aminoimidazole- (N-succinylocarboxamide) ribotide (SAICAR or 2-[5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamido]succinate) to 5-aminoimidazole-4-carboxamide ribotide (AICAR or 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide) and fumarate, and of adenylosuccinate (ADS or N(6)-(1,2-dicarboxyethyl)-AMP) to adenosine monophosphate (AMP) and fumarate.

211586:SO RS10675
gene id: 211586:SO_RS10675
uniprot id: Q8EEP9
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Glycosylated ar Arg-32 by EarP: arginine rhamnosylation is required for EF-P function and rescue of polyproline stalled ribosomes.
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

211586:SO RS10605
gene id: 211586:SO_RS10605
uniprot id: Q8EEQ7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the protease inhibitor I11 (ecotin) family.
messages: General inhibitor of family S1 serine proteases.
messages: Homodimer.
messages: Periplasm

211586:SO RS03430
gene id: 211586:SO_RS03430
uniprot id: Q8EIV3
names: Similarity
messages: Belongs to the UPF0251 family.

211586:SO RS15470
gene id: 211586:SO_RS15470
uniprot id: Q8EC27
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

211586:SO RS02440
gene id: 211586:SO_RS02440
uniprot id: Q8EJF5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

211586:SO RS16520
gene id: 211586:SO_RS16520
uniprot id: Q8EBI2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurJ/MviN family.
messages: Cell inner membrane
messages: Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.
messages: Membrane

211586:SO RS01895
gene id: 211586:SO_RS01895
uniprot id: Q8EJR8
names: Function
names: Similarity
messages: Belongs to the Dus family. DusB subfamily.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

211586:SO RS19295
gene id: 211586:SO_RS19295
uniprot id: Q8CMJ3
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

211586:SO RS00905
gene id: 211586:SO_RS00905
uniprot id: Q8EKA0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SelU family.
messages: Involved in the post-transcriptional modification of the uridine at the wobble position (U34) of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Catalyzes the conversion of 2-thiouridine (S2U-RNA) to 2-selenouridine (Se2U-RNA). Acts in a two-step process involving geranylation of 2-thiouridine (S2U) to S-geranyl-2-thiouridine (geS2U) and subsequent selenation of the latter derivative to 2-selenouridine (Se2U) in the tRNA chain.
messages: Monomer.

211586:SO RS19570
gene id: 211586:SO_RS19570
uniprot id: Q8E9P6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

211586:SO RS08410
gene id: 211586:SO_RS08410
uniprot id: Q8EFY6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane
messages: Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins.

211586:SO RS11030
gene id: 211586:SO_RS11030
uniprot id: Q8EEH6
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.

211586:SO RS13050
gene id: 211586:SO_RS13050
uniprot id: Q8EDE1
names: Subcellular Location Annotation
messages: Membrane

211586:SO RS05405
gene id: 211586:SO_RS05405
uniprot id: Q8CX46
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

211586:SO RS19220
gene id: 211586:SO_RS19220
uniprot id: Q8E9W4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
messages: Cell inner membrane

211586:SO RS06370
gene id: 211586:SO_RS06370
uniprot id: Q8EH59
names: Subcellular Location Annotation
messages: Membrane

211586:SO RS10395
gene id: 211586:SO_RS10395
uniprot id: Q8EEU8
names: Function
names: Similarity
messages: A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters.
messages: Belongs to the NifU family.

211586:SO RS21880
gene id: 211586:SO_RS21880
uniprot id: Q8E8F7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0324 family.
messages: Cell membrane

211586:SO RS03860
gene id: 211586:SO_RS03860
uniprot id: Q8EIL9
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

211586:SO RS20205
gene id: 211586:SO_RS20205
uniprot id: Q8E9D4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

211586:SO RS00810
gene id: 211586:SO_RS00810
uniprot id: Q8EKC0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP M family.
messages: Cell inner membrane
messages: Inner membrane component of the type II secretion system required for the energy-dependent secretion of extracellular factors such as proteases and toxins from the periplasm.
messages: Membrane

211586:SO RS00095
gene id: 211586:SO_RS00095
uniprot id: Q8EKS1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfur carrier protein TusA family.
messages: Cytoplasm
messages: Sulfur carrier protein which probably makes part of a sulfur-relay system.

211586:SO RS11230
gene id: 211586:SO_RS11230
uniprot id: Q8EED5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0073 (Hly-III) family.
messages: Membrane

211586:SO RS10390
gene id: 211586:SO_RS10390
uniprot id: Q8EEU9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.
messages: Cytoplasm
messages: Homodimer. Forms a heterotetramer with IscU, interacts with other sulfur acceptors.
messages: Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins.

211586:SO RS16295
gene id: 211586:SO_RS16295
uniprot id: Q8EBM5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Bcr/CmlA family.
messages: Cell inner membrane
messages: Membrane

211586:SO RS12130
gene id: 211586:SO_RS12130
uniprot id: Q8EDW1
names: Similarity
names: Subunit
messages: Belongs to the Nudix hydrolase family. NudJ subfamily.
messages: Monomer.

211586:SO RS09400
gene id: 211586:SO_RS09400
uniprot id: Q8EFE0
names: Function
names: Similarity
messages: Belongs to the RmuC family.
messages: Involved in DNA recombination.

211586:SO RS05095
gene id: 211586:SO_RS05095
uniprot id: Q8EHW1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LuxS family.
messages: Binds 1 Fe cation per subunit.
messages: Homodimer.
messages: Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD).

211586:SO RS01285
gene id: 211586:SO_RS01285
uniprot id: Q8EK35
names: Function
names: Similarity
messages: Belongs to the CcmH/CycL/Ccl2/NrfF family.
messages: Possible subunit of a heme lyase.

211586:SO RS04870
gene id: 211586:SO_RS04870
uniprot id: Q8EI07
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

211586:SO RS08665
gene id: 211586:SO_RS08665
uniprot id: Q8CMJ3
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

211586:SO RS14855
gene id: 211586:SO_RS14855
uniprot id: Q8ECF7
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

211586:SO RS18805
gene id: 211586:SO_RS18805
uniprot id: Q8EA61
names: PTM
messages: Binds 2 heme c groups covalently per subunit.

211586:SO RS09160
gene id: 211586:SO_RS09160
uniprot id: Q8EFJ1
names: Similarity
messages: Belongs to the NAPRTase family.

211586:SO RS12160
gene id: 211586:SO_RS12160
uniprot id: Q8EDV5
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

211586:SO RS08305
gene id: 211586:SO_RS08305
uniprot id: Q8EG07
names: Similarity
messages: Belongs to the PspA/IM30 family.

211586:SO RS13425
gene id: 211586:SO_RS13425
uniprot id: Q8ED70
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.

211586:SO RS06180
gene id: 211586:SO_RS06180
uniprot id: Q8EH96
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

211586:SO RS07595
gene id: 211586:SO_RS07595
uniprot id: Q8EGG0
names: Subcellular Location Annotation
messages: Cytoplasm

211586:SO RS11005
gene id: 211586:SO_RS11005
uniprot id: Q8EEI2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LapA family.
messages: Cell inner membrane
messages: Involved in the assembly of lipopolysaccharide (LPS).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

211586:SO RS01105
gene id: 211586:SO_RS01105
uniprot id: Q8EK67
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

211586:SO RS11010
gene id: 211586:SO_RS11010
uniprot id: Q8EEI1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial histone-like protein family.
messages: Heterodimer of an alpha and a beta chain.
messages: This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.

211586:SO RS04855
gene id: 211586:SO_RS04855
uniprot id: Q8EI10
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

211586:SO RS20475
gene id: 211586:SO_RS20475
uniprot id: Q8E976
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glutamine synthetase family.
messages: Cytoplasm
messages: Oligomer of 12 subunits arranged in the form of two hexagons.

211586:SO RS04710
gene id: 211586:SO_RS04710
uniprot id: Q8EI41
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 2 family.
messages: Cell inner membrane
messages: Membrane
messages: NDH-1 is composed of 13 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

211586:SO RS09625
gene id: 211586:SO_RS09625
uniprot id: Q8EF92
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. HypB/HupM subfamily.

211586:SO RS02040
gene id: 211586:SO_RS02040
uniprot id: Q8EJN9
names: Function
messages: Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).

211586:SO RS06220
gene id: 211586:SO_RS06220
uniprot id: Q8EH88
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily.
messages: Catalyzes the oxidation of L-aspartate to iminoaspartate.
messages: Cytoplasm

211586:SO RS09750
gene id: 211586:SO_RS09750
uniprot id: Q8EF68
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

211586:SO RS01500
gene id: 211586:SO_RS01500
uniprot id: Q8EJZ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Basic amino acid/polyamine antiporter (APA) (TC 2.A.3.2) family.
messages: Catalyzes both the uptake and excretion of putrescine. The uptake of putrescine is dependent on the membrane potential and the excretion involves putrescine-ornithine antiporter activity.
messages: Cell inner membrane
messages: Membrane

211586:SO RS06300
gene id: 211586:SO_RS06300
uniprot id: Q8EH72
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

211586:SO RS13395
gene id: 211586:SO_RS13395
uniprot id: Q8ED77
names: Subcellular Location Annotation
messages: Membrane

211586:SO RS01495
gene id: 211586:SO_RS01495
uniprot id: Q8EJZ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Gram-negative porin family.
messages: Cell outer membrane
messages: Membrane

211586:SO RS05390
gene id: 211586:SO_RS05390
uniprot id: Q8EHP9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transpeptidase family. MrdA subfamily.
messages: Catalyzes cross-linking of the peptidoglycan cell wall.
messages: Cell inner membrane

211586:SO RS04755
gene id: 211586:SO_RS04755
uniprot id: Q8EI32
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

211586:SO RS01185
gene id: 211586:SO_RS01185
uniprot id: P59124
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

211586:SO RS13495
gene id: 211586:SO_RS13495
uniprot id: Q8ED59
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FNT transporter (TC 2.A.44) family.
messages: Membrane

211586:SO RS17440
gene id: 211586:SO_RS17440
uniprot id: Q8EAZ2
names: Function
names: Similarity
names: Subunit
messages: Catalyzes the ADP transfer from ATP to D-glycero-beta-D-manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose.
messages: Catalyzes the phosphorylation of D-glycero-D-manno-heptose 7-phosphate at the C-1 position to selectively form D-glycero-beta-D-manno-heptose-1,7-bisphosphate.
messages: Homodimer.
messages: In the C-terminal section; belongs to the cytidylyltransferase family.
messages: In the N-terminal section; belongs to the carbohydrate kinase PfkB family.

211586:SO RS03930
gene id: 211586:SO_RS03930
uniprot id: Q8EIK2
names: Similarity
messages: Belongs to the class-D beta-lactamase family.

211586:SO RS08855
gene id: 211586:SO_RS08855
uniprot id: Q8EFQ2
names: Subcellular Location Annotation
messages: Membrane

211586:SO RS15180
gene id: 211586:SO_RS15180
uniprot id: Q8EC91
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FlgA family.
messages: Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly.
messages: Periplasm

211586:SO RS16525
gene id: 211586:SO_RS16525
uniprot id: Q8EBH9
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

211586:SO RS00125
gene id: 211586:SO_RS00125
uniprot id: Q8EKR5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HemG family.
messages: Binds 1 FMN non-covalently per subunit.
messages: Catalyzes the 6-electron oxidation of protoporphyrinogen IX to form protoporphyrin IX; under anaerobic conditions uses menaquinone as an electron acceptor, under aerobic conditions uses ubiquinone as an electron acceptor.
messages: Cell inner membrane

211586:SO RS04205
gene id: 211586:SO_RS04205
uniprot id: Q8EIE4
names: Similarity
messages: Belongs to the UPF0167 family.

211586:SO RS01635
gene id: 211586:SO_RS01635
uniprot id: Q8EJW4
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the PrpF family.
messages: Homodimer.
messages: Involved in the catabolism of short chain fatty acids (SCFA) via the 2-methylcitrate cycle II (propionate degradation route). PrpF catalyzes the cis-trans isomerization of 2-methyl-aconitate through a base-catalyzed proton abstraction coupled with a rotation about C2-C3 bond of 2-methyl-aconitate.
messages: Together with AcnD, they are able to restore the growth of prpD mutant on propionate.

211586:SO RS18420
gene id: 211586:SO_RS18420
uniprot id: Q8EAE9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the KdsC family.
messages: Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate.
messages: Homotetramer.

211586:SO RS00765
gene id: 211586:SO_RS00765
uniprot id: Q8EKC9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial secretin family. GSP D subfamily.
messages: Cell outer membrane
messages: Membrane

211586:SO RS02050
gene id: 211586:SO_RS02050
uniprot id: Q8EJN7
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

211586:SO RS13620
gene id: 211586:SO_RS13620
uniprot id: K4PST1
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

211586:SO RS17850
gene id: 211586:SO_RS17850
uniprot id: Q8EAR4
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

211586:SO RS22080
gene id: 211586:SO_RS22080
uniprot id: Q8E8B9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

211586:SO RS19465
gene id: 211586:SO_RS19465
uniprot id: Q8E9R2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

211586:SO RS17200
gene id: 211586:SO_RS17200
uniprot id: Q8EB47
names: Function
messages: May be involved in the biogenesis of curli organelles.

211586:SO RS21495
gene id: 211586:SO_RS21495
uniprot id: Q8E8N6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AB hydrolase superfamily. Carboxylesterase BioH family.
messages: Cytoplasm
messages: Monomer.
messages: The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters.

211586:SO RS08885
gene id: 211586:SO_RS08885
uniprot id: Q8EFP5
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

211586:SO RS05400
gene id: 211586:SO_RS05400
uniprot id: Q8EHP7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein uL14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein uL14 (rplN).

211586:SO RS01190
gene id: 211586:SO_RS01190
uniprot id: Q8EK52
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

211586:SO RS08900
gene id: 211586:SO_RS08900
uniprot id: K4PSF7
names: Cofactor
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cell inner membrane
messages: Membrane
messages: Membrane-anchoring subunit of succinate dehydrogenase (SDH).
messages: Part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur protein, plus two membrane-anchoring proteins, SdhC and SdhD.
messages: The heme is bound between the two transmembrane subunits.

211586:SO RS06190
gene id: 211586:SO_RS06190
uniprot id: Q8EH94
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

211586:SO RS16230
gene id: 211586:SO_RS16230
uniprot id: Q8EBN8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.

211586:SO RS06330
gene id: 211586:SO_RS06330
uniprot id: Q8EH67
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HCP family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Binds 1 hybrid [4Fe-2O-2S] cluster.
messages: Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O.
messages: Cytoplasm

211586:SO RS16440
gene id: 211586:SO_RS16440
uniprot id: Q8CMJ3
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

211586:SO RS10710
gene id: 211586:SO_RS10710
uniprot id: Q8EEP1
names: Similarity
messages: Belongs to the phosphohexose mutase family.

211586:SO RS02735
gene id: 211586:SO_RS02735
uniprot id: Q8EJ92
names: Similarity
messages: Belongs to the PhoH family.

211586:SO RS17350
gene id: 211586:SO_RS17350
uniprot id: Q8EB13
names: Function
names: Similarity
messages: Belongs to the APS kinase family.
messages: Catalyzes the synthesis of activated sulfate.

211586:SO RS07395
gene id: 211586:SO_RS07395
uniprot id: Q8EGK0
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

211586:SO RS00650
gene id: 211586:SO_RS00650
uniprot id: Q8EKF7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

211586:SO RS04170
gene id: 211586:SO_RS04170
uniprot id: Q8EIF2
names: Similarity
messages: Belongs to the agmatine deiminase family.

211586:SO RS06930
gene id: 211586:SO_RS06930
uniprot id: Q8EGU8
names: Similarity
messages: Belongs to the disproportionating enzyme family.

211586:SO RS16150
gene id: 211586:SO_RS16150
uniprot id: Q8EBQ4
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

211586:SO RS17520
gene id: 211586:SO_RS17520
uniprot id: Q8EAY1
names: Function
names: Similarity
messages: Belongs to the GlnE family.
messages: Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell.

211586:SO RS05675
gene id: 211586:SO_RS05675
uniprot id: Q8EHK2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phosphopentomutase family.
messages: Binds 1 or 2 manganese ions.
messages: Cytoplasm
messages: Phosphotransfer between the C1 and C5 carbon atoms of pentose.

211586:SO RS04380
gene id: 211586:SO_RS04380
uniprot id: Q8EIB0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class II fructose-bisphosphate aldolase family.
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.
messages: Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.
messages: One is catalytic and the other provides a structural contribution.

211586:SO RS14655
gene id: 211586:SO_RS14655
uniprot id: Q8ECJ7
names: Similarity
messages: Belongs to the ETF beta-subunit/FixA family.

211586:SO RS02610
gene id: 211586:SO_RS02610
uniprot id: Q8EJB8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

211586:SO RS04660
gene id: 211586:SO_RS04660
uniprot id: Q8EI53
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

211586:SO RS04740
gene id: 211586:SO_RS04740
uniprot id: Q8EI35
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 1 family.
messages: Cell inner membrane
messages: NDH-1 is composed of 13 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.

211586:SO RS08215
gene id: 211586:SO_RS08215
uniprot id: Q8EG21
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

211586:SO RS12845
gene id: 211586:SO_RS12845
uniprot id: Q8EDH5
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

211586:SO RS03975
gene id: 211586:SO_RS03975
uniprot id: Q8EIJ1
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. NasA/NapA/NarB subfamily.
messages: Binds 1 [4Fe-4S] cluster.
messages: Binds 1 molybdenum-bis(molybdopterin guanine dinucleotide) (Mo-bis-MGD) cofactor per subunit.
messages: Catalytic subunit of the periplasmic nitrate reductase complex NapAB. Receives electrons from NapB and catalyzes the reduction of nitrate to nitrite.
messages: Component of the periplasmic nitrate reductase NapAB complex composed of NapA and NapB.
messages: Periplasm
messages: Predicted to be exported by the Tat system. The position of the signal peptide cleavage has not been experimentally proven.

211586:SO RS10445
gene id: 211586:SO_RS10445
uniprot id: Q8EET9
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

211586:SO RS10510
gene id: 211586:SO_RS10510
uniprot id: Q8EES6
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

211586:SO RS00030
gene id: 211586:SO_RS00030
uniprot id: Q8EKT4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RnpA family.
messages: Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.
messages: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.

211586:SO RS06010
gene id: 211586:SO_RS06010
uniprot id: Q8EHD1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A highly abundant outer membrane lipoprotein that controls the distance between the inner and outer membranes. The only protein known to be covalently linked to the peptidoglycan network (PGN). Also non-covalently binds the PGN. The link between the cell outer membrane and PGN contributes to maintenance of the structural and functional integrity of the cell envelope, and maintains the correct distance between the PGN and the outer membrane.
messages: Belongs to the Lpp family.
messages: Cell outer membrane
messages: Homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: cell wall

211586:SO RS17725
gene id: 211586:SO_RS17725
uniprot id: Q8EAT7
names: Function
names: Similarity
messages: Belongs to the MurCDEF family. Mpl subfamily.
messages: Reutilizes the intact tripeptide L-alanyl-gamma-D-glutamyl-meso-diaminopimelate by linking it to UDP-N-acetylmuramate.

211586:SO RS22840
gene id: 211586:SO_RS22840
uniprot id: Q8E808
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

211586:SO RS07995
gene id: 211586:SO_RS07995
uniprot id: Q8EG66
names: Disruption Phenotype
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. OleA family.
messages: Deletion of the entire oleABCD gene cluster leads to the complete absence of nonpolar extractable products. The oleABCD deletion strain shows a significantly longer lag phase than the wild-type strain when shifted to a lower temperature.
messages: Involved in olefin biosynthesis (PubMed:20418444). Catalyzes a non-decarboxylative head-to-head Claisen condensation of two acyl-CoA molecules, generating an (R)-2-alkyl-3-oxoalkanoate (By similarity). The S.oneidensis oleABCD genes produce 3,6,9,12,15,19,22,25,28-hentriacontanonaene, which may aid the cells in adapting to a sudden drop in temperature (PubMed:20418444).

211586:SO RS04765
gene id: 211586:SO_RS04765
uniprot id: Q8EI30
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 20 kDa subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Cell inner membrane
messages: NDH-1 is composed of 13 different subunits. Subunits NuoB, CD, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

211586:SO RS00485
gene id: 211586:SO_RS00485
uniprot id: Q8EKJ4
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAL/histidase family.
messages: Contains an active site 4-methylidene-imidazol-5-one (MIO), which is formed autocatalytically by cyclization and dehydration of residues Ala-Ser-Gly.
messages: Cytoplasm

211586:SO RS08350
gene id: 211586:SO_RS08350
uniprot id: Q8EFZ9
names: Similarity
messages: Belongs to the histone deacetylase family.

211586:SO RS07235
gene id: 211586:SO_RS07235
uniprot id: Q8EGN8
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M1 family.
messages: Binds 1 zinc ion per subunit.

211586:SO RS05120
gene id: 211586:SO_RS05120
uniprot id: Q8EHV6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell inner membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

211586:SO RS02990
gene id: 211586:SO_RS02990
uniprot id: Q8EJ43
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

211586:SO RS18160
gene id: 211586:SO_RS18160
uniprot id: Q8EAK1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase class-III family.
messages: Binds 2 Fe(2+) ions per subunit.
messages: Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes.

211586:SO RS14485
gene id: 211586:SO_RS14485
uniprot id: Q8ECL6
names: Similarity
messages: Belongs to the CIA30 family.

211586:SO RS04580
gene id: 211586:SO_RS04580
uniprot id: Q8EI71
names: Similarity
messages: Belongs to the OsmC/Ohr family.

211586:SO RS09320
gene id: 211586:SO_RS09320
uniprot id: Q8EFF2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.
messages: Homodimer.

211586:SO RS09510
gene id: 211586:SO_RS09510
uniprot id: Q8EFB5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

211586:SO RS18035
gene id: 211586:SO_RS18035
uniprot id: Q8EAM4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

211586:SO RS01600
gene id: 211586:SO_RS01600
uniprot id: Q8EJX1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ZapB family.
messages: Cytoplasm
messages: Homodimer. The ends of the coiled-coil dimer bind to each other, forming polymers. Interacts with FtsZ.
messages: Non-essential, abundant cell division factor that is required for proper Z-ring formation. It is recruited early to the divisome by direct interaction with FtsZ, stimulating Z-ring assembly and thereby promoting cell division earlier in the cell cycle. Its recruitment to the Z-ring requires functional FtsA or ZipA.

211586:SO RS14020
gene id: 211586:SO_RS14020
uniprot id: Q8ECV0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

211586:SO RS19615
gene id: 211586:SO_RS19615
uniprot id: Q8E9N7
names: Activity Regulation
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Inhibited by fructose 1,6-bisphosphate (FBP).
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.

211586:SO RS03815
gene id: 211586:SO_RS03815
uniprot id: Q8EIM8
names: Activity Regulation
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.
messages: Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.
messages: Belongs to the carbohydrate kinase pfkB family.
messages: Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate.

211586:SO RS11180
gene id: 211586:SO_RS11180
uniprot id: Q8EEE4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

211586:SO RS03540
gene id: 211586:SO_RS03540
uniprot id: Q8EIT4
names: Similarity
messages: Belongs to the glutamate synthase family.

211586:SO RS19095
gene id: 211586:SO_RS19095
uniprot id: Q8E9Z2
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

211586:SO RS18380
gene id: 211586:SO_RS18380
uniprot id: Q8EAF6
names: Similarity
messages: Belongs to the BolA/IbaG family.

211586:SO RS17395
gene id: 211586:SO_RS17395
uniprot id: Q8EB02
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 51 family.
messages: Cell inner membrane
messages: Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors.

211586:SO RS04760
gene id: 211586:SO_RS04760
uniprot id: Q8EI31
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Cell inner membrane
messages: In the C-terminal section; belongs to the complex I 49 kDa subunit family.
messages: In the N-terminal section; belongs to the complex I 30 kDa subunit family.
messages: NDH-1 is composed of 13 different subunits. Subunits NuoB, CD, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

211586:SO RS08205
gene id: 211586:SO_RS08205
uniprot id: Q8EG23
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

211586:SO RS04700
gene id: 211586:SO_RS04700
uniprot id: Q8EI43
names: Subcellular Location Annotation
messages: Membrane

211586:SO RS18375
gene id: 211586:SO_RS18375
uniprot id: Q8EAF7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm

211586:SO RS21400
gene id: 211586:SO_RS21400
uniprot id: Q8E8Q4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Cell membrane
messages: Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.
messages: Membrane

211586:SO RS07525
gene id: 211586:SO_RS07525
uniprot id: Q8EGH4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

211586:SO RS03820
gene id: 211586:SO_RS03820
uniprot id: Q8EIM7
names: Function
names: Similarity
messages: Belongs to the IUNH family. RihA subfamily.
messages: Hydrolyzes cytidine or uridine to ribose and cytosine or uracil, respectively.

211586:SO RS00105
gene id: 211586:SO_RS00105
uniprot id: Q8EKR9
names: Function
names: Similarity
names: Subunit
messages: Heterotetramer of two alpha chains (FadB) and two beta chains (FadA).
messages: In the C-terminal section; belongs to the 3-hydroxyacyl-CoA dehydrogenase family.
messages: In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family.
messages: Involved in the aerobic and anaerobic degradation of long-chain fatty acids via beta-oxidation cycle. Catalyzes the formation of 3-oxoacyl-CoA from enoyl-CoA via L-3-hydroxyacyl-CoA. It can also use D-3-hydroxyacyl-CoA and cis-3-enoyl-CoA as substrate.

211586:SO RS16535
gene id: 211586:SO_RS16535
uniprot id: Q8EBH7
names: Subcellular Location Annotation
messages: Endoplasmic reticulum
messages: Golgi apparatus
messages: Lysosome

211586:SO RS10720
gene id: 211586:SO_RS10720
uniprot id: Q8EEN9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the AspA/AstE family. Succinylglutamate desuccinylase subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Transforms N(2)-succinylglutamate into succinate and glutamate.

211586:SO RS18455
gene id: 211586:SO_RS18455
uniprot id: Q8EAE2
names: Function
names: Similarity
messages: Belongs to the RapZ-like family.
messages: Displays ATPase and GTPase activities.

211586:SO RS08005
gene id: 211586:SO_RS08005
uniprot id: Q8EG64
names: Disruption Phenotype
names: Function
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.
messages: Deletion of the entire oleABCD gene cluster leads to the complete absence of nonpolar extractable products. The oleABCD deletion strain shows a significantly longer lag phase than the wild-type strain when shifted to a lower temperature.
messages: Involved in olefin biosynthesis (PubMed:20418444). Catalyzes the conversion of 2-alkyl-3-hydroxyalkanoic acids to beta-lactones in the presence of ATP (By similarity). The S.oneidensis oleABCD genes produce 3,6,9,12,15,19,22,25,28-hentriacontanonaene, which may aid the cells in adapting to a sudden drop in temperature (PubMed:20418444).

211586:SO RS10455
gene id: 211586:SO_RS10455
uniprot id: Q8EET7
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

211586:SO RS17880
gene id: 211586:SO_RS17880
uniprot id: Q8EAQ8
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

211586:SO RS20265
gene id: 211586:SO_RS20265
uniprot id: Q8E9C0
names: Function
names: Similarity
messages: Belongs to the helicase family. RecG subfamily.
messages: Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA).

211586:SO RS17370
gene id: 211586:SO_RS17370
uniprot id: Q8EB08
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

211586:SO RS08250
gene id: 211586:SO_RS08250
uniprot id: Q8EG17
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

211586:SO RS04300
gene id: 211586:SO_RS04300
uniprot id: Q8EIC6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the YjjX NTPase family.
messages: Binds 1 divalent metal cation per subunit; can use either Mg(2+) or Mn(2+).
messages: Homodimer.
messages: Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA/RNA precursor pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

211586:SO RS08210
gene id: 211586:SO_RS08210
uniprot id: Q8EG22
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

211586:SO RS04830
gene id: 211586:SO_RS04830
uniprot id: Q8EI16
names: Function
names: Similarity
messages: Belongs to the CobU/CobP family.
messages: Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate.

211586:SO RS11410
gene id: 211586:SO_RS11410
uniprot id: Q8EEA0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Catalyzes the dehydration of 6-phospho-D-gluconate to 2-dehydro-3-deoxy-6-phospho-D-gluconate.

211586:SO RS11330
gene id: 211586:SO_RS11330
uniprot id: Q8EEB8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

211586:SO RS05845
gene id: 211586:SO_RS05845
uniprot id: Q8EHG2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

211586:SO RS15310
gene id: 211586:SO_RS15310
uniprot id: Q8EC66
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

211586:SO RS02805
gene id: 211586:SO_RS02805
uniprot id: Q8EJ79
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

211586:SO RS17005
gene id: 211586:SO_RS17005
uniprot id: Q8EB91
names: Function
names: Similarity
messages: Belongs to the Ap4A hydrolase family.
messages: Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP.

211586:SO RS15370
gene id: 211586:SO_RS15370
uniprot id: Q8EC50
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseA family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

211586:SO RS04860
gene id: 211586:SO_RS04860
uniprot id: Q8EI09
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

211586:SO RS13310
gene id: 211586:SO_RS13310
uniprot id: Q8ED91
names: Similarity
messages: Belongs to the ArsC family.

211586:SO RS12650
gene id: 211586:SO_RS12650
uniprot id: Q8EDK4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

211586:SO RS07250
gene id: 211586:SO_RS07250
uniprot id: Q8EGN7
names: Similarity
messages: Belongs to the glutathione peroxidase family.

211586:SO RS19580
gene id: 211586:SO_RS19580
uniprot id: Q8E9P4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

211586:SO RS08545
gene id: 211586:SO_RS08545
uniprot id: Q8EFW0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ribosome modulation factor family.
messages: Cytoplasm
messages: During stationary phase, converts 70S ribosomes to an inactive dimeric form (100S ribosomes).

211586:SO RS22065
gene id: 211586:SO_RS22065
uniprot id: Q8E8C2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
messages: Cytoplasm
messages: Homotrimer.
messages: In the C-terminal section; belongs to the transferase hexapeptide repeat family.
messages: In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.

211586:SO RS02545
gene id: 211586:SO_RS02545
uniprot id: Q8EJD2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0718 family.
messages: Cell membrane
messages: Membrane

211586:SO RS16020
gene id: 211586:SO_RS16020
uniprot id: Q8EBS1
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

211586:SO RS08870
gene id: 211586:SO_RS08870
uniprot id: Q8EFP8
names: Function
names: Similarity
messages: Belongs to the N(4)-acetylcytidine amidohydrolase family.
messages: Catalyzes the hydrolysis of N(4)-acetylcytidine (ac4C).

211586:SO RS16540
gene id: 211586:SO_RS16540
uniprot id: Q8EBH6
names: Similarity
messages: Belongs to the UPF0246 family.

211586:SO RS13415
gene id: 211586:SO_RS13415
uniprot id: Q8ED72
names: Similarity
messages: Belongs to the UPF0178 family.

211586:SO RS02895
gene id: 211586:SO_RS02895
uniprot id: Q8EJ63
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome b family.
messages: Binds 2 heme groups non-covalently.
messages: Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.
messages: Membrane
messages: The main subunits of complex b-c1 are: cytochrome b, cytochrome c1 and the Rieske protein.

211586:SO RS19785
gene id: 211586:SO_RS19785
uniprot id: Q8E9K5
names: Activity Regulation
names: Function
names: Miscellaneous
names: Subunit
messages: Adenylyltransferase activity is inhibited by the inhibitory helix present at the N-terminus: Glu-73 binds ATP and competes with ATP-binding at Arg-209, thereby preventing adenylyltransferase activity. Activation dissociates ATP-binding from Glu-73, allowing ordered binding of the entire ATP moiety with the alpha-phosphate in an orientation that is productive for accepting an incoming target hydroxyl side chain.
messages: Adenylyltransferase that mediates the addition of adenosine 5'-monophosphate (AMP) to specific residues of target proteins.
messages: Defined as class II fido-domain containing proteins, in which the inhibitory helix is present at the N-terminus of the Fido domain.
messages: Homodimer.

211586:SO RS13440
gene id: 211586:SO_RS13440
uniprot id: Q8ED68
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CysZ family.
messages: Cell inner membrane
messages: High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway.

211586:SO RS14055
gene id: 211586:SO_RS14055
uniprot id: Q8ECU1
names: Similarity
messages: Belongs to the IucA/IucC family.

211586:SO RS03960
gene id: 211586:SO_RS03960
uniprot id: Q8EIJ4
names: Disruption Phenotype
names: Function
names: Induction
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NapB family.
messages: Binds 2 heme C groups per subunit.
messages: By nitrate or fumarate under anaerobic conditions.
messages: Component of the periplasmic nitrate reductase NapAB complex composed of NapA and NapB.
messages: Electron transfer subunit of the periplasmic nitrate reductase complex NapAB. Receives electrons from the membrane-anchored tetraheme c-type CymA protein and transfers these to NapA subunit, thus allowing electron flow between membrane and periplasm. Not essential for nitrate reduction but confers advantage to the organism when grown on nitrate and thereby a fitness gain in utilizing nitrate.
messages: Mutants exhibit 15% slower rate of nitrate reduction compared to mutants for other genes in the NAP operon. Mutants can grow on nitrate to maximum cell density earlier than wild-type. Nitrite is not detected in mutant strains but ammonium reaches detectable levels sooner than in wild-type and accumulates to same level as in wild-type. Double mutants with deletions of both NapA and NapB fail to grow on nitrate or reduce nitrate under anaerobic conditions. Double mutants for both NapB and NrfA reduces nitrate as fast as wild-type.
messages: Periplasm

211586:SO RS03275
gene id: 211586:SO_RS03275
uniprot id: Q8EIY7
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

211586:SO RS06045
gene id: 211586:SO_RS06045
uniprot id: Q8EHC6
names: Subcellular Location Annotation
messages: Membrane

211586:SO RS01990
gene id: 211586:SO_RS01990
uniprot id: Q8EJQ0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ZapD family.
messages: Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity.
messages: Cytoplasm
messages: Interacts with FtsZ.

211586:SO RS17865
gene id: 211586:SO_RS17865
uniprot id: Q8EAR1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LolB family.
messages: Cell outer membrane
messages: Monomer.
messages: Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein.

211586:SO RS04460
gene id: 211586:SO_RS04460
uniprot id: Q8EI95
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. tRNA (adenine-N(6)-)-methyltransferase family.
messages: Cytoplasm
messages: Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC).

211586:SO RS19275
gene id: 211586:SO_RS19275
uniprot id: Q8E9V0
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: Allosterically activated by HslU binding.
messages: Belongs to the peptidase T1B family. HslV subfamily.
messages: Cytoplasm
messages: Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.

211586:SO RS21625
gene id: 211586:SO_RS21625
uniprot id: Q8E8K9
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Membrane
messages: Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (CysA), two transmembrane proteins (CysT and CysW) and a solute-binding protein (CysP).

211586:SO RS22050
gene id: 211586:SO_RS22050
uniprot id: Q8CX33
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

211586:SO RS21250
gene id: 211586:SO_RS21250
uniprot id: Q8E8T3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the AB hydrolase superfamily. MenH family.
messages: Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC).
messages: Monomer.

211586:SO RS18335
gene id: 211586:SO_RS18335
uniprot id: Q8EAG3
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

211586:SO RS21700
gene id: 211586:SO_RS21700
uniprot id: Q8E8J5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
messages: Single-chain monomer with multiple functions.

211586:SO RS19715
gene id: 211586:SO_RS19715
uniprot id: Q8E9L9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the nucleoid occlusion factor SlmA family.
messages: Homodimer. Interacts with FtsZ.
messages: Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid. Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers. SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions.
messages: nucleoid

211586:SO RS12075
gene id: 211586:SO_RS12075
uniprot id: Q8EDX1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

211586:SO RS03870
gene id: 211586:SO_RS03870
uniprot id: Q8EIL7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell outer membrane

211586:SO RS04745
gene id: 211586:SO_RS04745
uniprot id: Q8EI34
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the complex I 75 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: Binds 3 [4Fe-4S] clusters per subunit.
messages: Composed of 13 different subunits. Subunits NuoCD, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity).

211586:SO RS15345
gene id: 211586:SO_RS15345
uniprot id: Q8EC57
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: In the N-terminal section; belongs to the FGAMS family.
messages: Monomer.
messages: Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.

211586:SO RS18415
gene id: 211586:SO_RS18415
uniprot id: Q8EAF0
names: Similarity
messages: Belongs to the SIS family. GutQ/KpsF subfamily.

211586:SO RS15445
gene id: 211586:SO_RS15445
uniprot id: Q8EC32
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

211586:SO RS08355
gene id: 211586:SO_RS08355
uniprot id: Q8EFZ8
names: Similarity
messages: Belongs to the UPF0319 family.

211586:SO RS11550
gene id: 211586:SO_RS11550
uniprot id: Q8EE80
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfB subfamily.
messages: Binds 3 [4Fe-4S] clusters.
messages: Cell inner membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

211586:SO RS20115
gene id: 211586:SO_RS20115
uniprot id: Q8E9F5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiK family.
messages: Cytoplasm
messages: Required for efficient ubiquinone (coenzyme Q) biosynthesis. UbiK is probably an accessory factor of Ubi enzymes and facilitates ubiquinone biosynthesis by acting as an assembly factor, a targeting factor, or both.

211586:SO RS11055
gene id: 211586:SO_RS11055
uniprot id: Q8EEH1
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

211586:SO RS06175
gene id: 211586:SO_RS06175
uniprot id: Q8EH97
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm

211586:SO RS17365
gene id: 211586:SO_RS17365
uniprot id: Q8EB09
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PAPS reductase family. CysD subfamily.
messages: Heterodimer composed of CysD, the smaller subunit, and CysN.
messages: With CysN forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway. APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD.

211586:SO RS09075
gene id: 211586:SO_RS09075
uniprot id: Q8EFK8
names: Similarity
messages: Belongs to the homogentisate dioxygenase family.

211586:SO RS00745
gene id: 211586:SO_RS00745
uniprot id: Q8EKD3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Cytoplasm
messages: Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.
messages: Monomer.

211586:SO RS12870
gene id: 211586:SO_RS12870
uniprot id: Q8EDH0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsX family.
messages: Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
messages: Cytoplasm
messages: Homodimer. Probably interacts with PlsY.

211586:SO RS17240
gene id: 211586:SO_RS17240
uniprot id: Q8EB40
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
messages: Homodimer.

211586:SO RS10725
gene id: 211586:SO_RS10725
uniprot id: Q8EEN8
names: Function
names: Similarity
messages: Belongs to the BCKDHA family.
messages: The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3).

211586:SO RS08490
gene id: 211586:SO_RS08490
uniprot id: Q8EFW7
names: Disruption Phenotype
names: Function
names: Induction
names: Subunit
messages: Deletion of the gene leads to a dramatically reduced growth at low temperature.
messages: Interacts with AtcC, but not with AtcA and AtcJ (PubMed:31482142). Interacts with the RNA polymerase subunits RpoB and RpoC (PubMed:33341675).
messages: Involved in cold adaptation (PubMed:31482142). Directly interacts with the RNA polymerase and decreases its activity (PubMed:33341675). May direct the DnaK chaperone to the RNA polymerase to sustain life at low temperatures (PubMed:33341675). Overproduction prevents bacterial growth due to RNA polymerase inhibition (PubMed:33341675).
messages: Part of the atcJABC operon (PubMed:31482142). The operon is constitutively expressed, and expression shows only a very slight increase at low temperature (PubMed:31482142).

211586:SO RS06890
gene id: 211586:SO_RS06890
uniprot id: Q8EGV9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

211586:SO RS21080
gene id: 211586:SO_RS21080
uniprot id: K4PU47
names: Similarity
messages: Belongs to the peptidase M16 family.

211586:SO RS07695
gene id: 211586:SO_RS07695
uniprot id: Q8EGD7
names: Similarity
messages: Belongs to the pterin-4-alpha-carbinolamine dehydratase family.

211586:SO RS03910
gene id: 211586:SO_RS03910
uniprot id: Q8EIK7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

211586:SO RS14760
gene id: 211586:SO_RS14760
uniprot id: Q8ECH5
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

211586:SO RS06850
gene id: 211586:SO_RS06850
uniprot id: Q8EGW8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

211586:SO RS22110
gene id: 211586:SO_RS22110
uniprot id: Q8E8B3
names: Subcellular Location Annotation
messages: Membrane

211586:SO RS19565
gene id: 211586:SO_RS19565
uniprot id: Q8E9P7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEDS family. FtsW subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Peptidoglycan polymerase that is essential for cell division.

211586:SO RS18290
gene id: 211586:SO_RS18290
uniprot id: Q8EAH3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PriB family.
messages: Binds single-stranded DNA at the primosome assembly site (PAS).
messages: Component of the preprimosomal complex composed of PriA, PriB, PriC, DnaB and DnaT. Upon transient interaction with DnaG it forms the primosome.

211586:SO RS07800
gene id: 211586:SO_RS07800
uniprot id: Q8EGB4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the calycin superfamily. Lipocalin family.
messages: Cell outer membrane
messages: Homodimer.
messages: Involved in the storage or transport of lipids necessary for membrane maintenance under stressful conditions. Displays a binding preference for lysophospholipids.

211586:SO RS05915
gene id: 211586:SO_RS05915
uniprot id: Q8EHE8
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

211586:SO RS19460
gene id: 211586:SO_RS19460
uniprot id: Q8E9R3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatB family.
messages: Cell inner membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

211586:SO RS15050
gene id: 211586:SO_RS15050
uniprot id: Q8ECB7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliH family.
messages: Cytoplasm
messages: Needed for flagellar regrowth and assembly.

211586:SO RS13460
gene id: 211586:SO_RS13460
uniprot id: Q8ED64
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

211586:SO RS01255
gene id: 211586:SO_RS01255
uniprot id: Q8EK41
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmB/CycW/HelB family.
messages: Cell inner membrane
messages: Membrane
messages: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.

211586:SO RS00815
gene id: 211586:SO_RS00815
uniprot id: Q8EKB9
names: Similarity
messages: Belongs to the GSP N family.

211586:SO RS06265
gene id: 211586:SO_RS06265
uniprot id: Q8EH79
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

211586:SO RS16385
gene id: 211586:SO_RS16385
uniprot id: Q8EBK8
names: Cofactor
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. NagA family.
messages: Binds 1 divalent metal cation per subunit.

211586:SO RS12110
gene id: 211586:SO_RS12110
uniprot id: Q8EDW4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ClpS family.
messages: Binds to the N-terminal domain of the chaperone ClpA.
messages: Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation.

211586:SO RS02935
gene id: 211586:SO_RS02935
uniprot id: P59320
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: May also have succinyldiaminopimelate aminotransferase activity, thus carrying out the corresponding step in lysine biosynthesis.

211586:SO RS14285
gene id: 211586:SO_RS14285
uniprot id: K4PW14
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Reduced FMN (FMNH(2)).

211586:SO RS16040
gene id: 211586:SO_RS16040
uniprot id: Q8EBR8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoS subfamily.
messages: Cytoplasm
messages: Interacts with the RNA polymerase core enzyme.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the master transcriptional regulator of the stationary phase and the general stress response.

211586:SO RS00185
gene id: 211586:SO_RS00185
uniprot id: Q8EKQ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SUA5 family. TsaC subfamily.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Catalyzes the conversion of L-threonine, HCO(3)(-)/CO(2) and ATP to give threonylcarbamoyl-AMP (TC-AMP) as the acyladenylate intermediate, with the release of diphosphate.

211586:SO RS20880
gene id: 211586:SO_RS20880
uniprot id: Q8E901
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

211586:SO RS18720
gene id: 211586:SO_RS18720
uniprot id: Q8EA80
names: Subcellular Location Annotation
messages: Membrane

211586:SO RS17650
gene id: 211586:SO_RS17650
uniprot id: Q8EAV1
names: Similarity
messages: Belongs to the SufE family.

211586:SO RS12785
gene id: 211586:SO_RS12785
uniprot id: Q8EDI8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

211586:SO RS02905
gene id: 211586:SO_RS02905
uniprot id: Q8EJ61
names: Similarity
messages: Belongs to the GST superfamily. HSP26 family.

211586:SO RS17960
gene id: 211586:SO_RS17960
uniprot id: Q8CMJ3
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

211586:SO RS19215
gene id: 211586:SO_RS19215
uniprot id: Q8E9W5
names: Subcellular Location Annotation
messages: Membrane

211586:SO RS06225
gene id: 211586:SO_RS06225
uniprot id: Q8EH87
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

211586:SO RS14605
gene id: 211586:SO_RS14605
uniprot id: Q8ECK3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

211586:SO RS04670
gene id: 211586:SO_RS04670
uniprot id: Q8EI50
names: Subcellular Location Annotation
messages: Membrane

211586:SO RS15005
gene id: 211586:SO_RS15005
uniprot id: Q8ECC6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliQ/MopD/SpaQ family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

211586:SO RS05930
gene id: 211586:SO_RS05930
uniprot id: Q8EHE5
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

211586:SO RS06015
gene id: 211586:SO_RS06015
uniprot id: K4PW05
names: Cofactor
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: A single active site specifically recognizes both ATP and CTP and is responsible for their addition.
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. Bacterial CCA-adding enzyme type 1 subfamily.
messages: Catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. tRNA 3'-terminal CCA addition is required both for tRNA processing and repair. Also involved in tRNA surveillance by mediating tandem CCA addition to generate a CCACCA at the 3' terminus of unstable tRNAs. While stable tRNAs receive only 3'-terminal CCA, unstable tRNAs are marked with CCACCA and rapidly degraded.
messages: Comprises two domains: an N-terminal domain containing the nucleotidyltransferase activity and a C-terminal HD domain associated with both phosphodiesterase and phosphatase activities.
messages: Magnesium is required for nucleotidyltransferase activity.
messages: Monomer. Can also form homodimers and oligomers.
messages: Nickel for phosphatase activity.

211586:SO RS21255
gene id: 211586:SO_RS21255
uniprot id: Q8E8T2
names: Function
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family. MenC type 1 subfamily.
messages: Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC) to 2-succinylbenzoate (OSB).

211586:SO RS06640
gene id: 211586:SO_RS06640
uniprot id: Q8EH03
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.

211586:SO RS03890
gene id: 211586:SO_RS03890
uniprot id: Q8EIL2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lactate permease family.
messages: Cell inner membrane
messages: Membrane
messages: Uptake of L-lactate across the membrane. Can also transport D-lactate and glycolate.

211586:SO RS07575
gene id: 211586:SO_RS07575
uniprot id: Q8EGG4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioester dehydratase family. FabZ subfamily.
messages: Cytoplasm
messages: Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.

211586:SO RS18685
gene id: 211586:SO_RS18685
uniprot id: Q8EA88
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

211586:SO RS12050
gene id: 211586:SO_RS12050
uniprot id: Q8EDX6
names: Similarity
names: Subunit
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.

211586:SO RS05445
gene id: 211586:SO_RS05445
uniprot id: Q8EHN9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

211586:SO RS09645
gene id: 211586:SO_RS09645
uniprot id: Q8EF88
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HupC/HyaC/HydC family.
messages: Membrane

211586:SO RS21430
gene id: 211586:SO_RS21430
uniprot id: Q8E8P8
names: Subcellular Location Annotation
messages: Membrane

211586:SO RS00155
gene id: 211586:SO_RS00155
uniprot id: Q8EKQ9
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

211586:SO RS22320
gene id: 211586:SO_RS22320
uniprot id: Q8E882
names: Function
names: Similarity
messages: Belongs to the PemK/MazF family.
messages: Toxic component of a type II toxin-antitoxin (TA) system.

211586:SO RS12510
gene id: 211586:SO_RS12510
uniprot id: Q8EDN3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DoxX family.
messages: Membrane

211586:SO RS00100
gene id: 211586:SO_RS00100
uniprot id: Q8EKS0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. Thiolase family.
messages: Catalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed.
messages: Cytoplasm
messages: Heterotetramer of two alpha chains (FadB) and two beta chains (FadA).

211586:SO RS10585
gene id: 211586:SO_RS10585
uniprot id: Q8EER2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LolA family.
messages: Monomer.
messages: Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane).
messages: Periplasm

211586:SO RS01175
gene id: 211586:SO_RS01175
uniprot id: Q8EK54
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

211586:SO RS15015
gene id: 211586:SO_RS15015
uniprot id: Q8ECC4
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliO/MopB family.
messages: Cell membrane

211586:SO RS05145
gene id: 211586:SO_RS05145
uniprot id: Q8EHV1
names: Function
names: Similarity
messages: Belongs to the bacterioferritin family.
messages: Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex.

211586:SO RS21160
gene id: 211586:SO_RS21160
uniprot id: Q8E8V1
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Bcr/CmlA family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

211586:SO RS09080
gene id: 211586:SO_RS09080
uniprot id: Q8EFK6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

211586:SO RS15700
gene id: 211586:SO_RS15700
uniprot id: Q8EBX7
names: Cofactor
names: Function
names: Similarity
messages: Adenine glycosylase active on G-A mispairs. MutY also corrects error-prone DNA synthesis past GO lesions which are due to the oxidatively damaged form of guanine: 7,8-dihydro-8-oxoguanine (8-oxo-dGTP).
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.

211586:SO RS00250
gene id: 211586:SO_RS00250
uniprot id: Q8EKP4
names: Similarity
messages: Belongs to the peptidase S41A family.

211586:SO RS10970
gene id: 211586:SO_RS10970
uniprot id: Q8CMJ3
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

211586:SO RS21995
gene id: 211586:SO_RS21995
uniprot id: Q8E8D4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenosine deaminase subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolytic deamination of adenosine and 2-deoxyadenosine.

211586:SO RS10415
gene id: 211586:SO_RS10415
uniprot id: Q8EEU4
names: Similarity
messages: Belongs to the adrenodoxin/putidaredoxin family.

211586:SO RS01130
gene id: 211586:SO_RS01130
uniprot id: P59183
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

211586:SO RS13750
gene id: 211586:SO_RS13750
uniprot id: Q8ED07
names: Similarity
messages: Belongs to the peptidase S14 family.

211586:SO RS15095
gene id: 211586:SO_RS15095
uniprot id: Q8ECA8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum
messages: Belongs to the FliD family.
messages: Homopentamer.
messages: Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.
messages: Secreted

211586:SO RS08710
gene id: 211586:SO_RS08710
uniprot id: Q8EFT2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

211586:SO RS19435
gene id: 211586:SO_RS19435
uniprot id: Q8E9R8
names: Similarity
messages: Belongs to the arginase family.

211586:SO RS17720
gene id: 211586:SO_RS17720
uniprot id: Q8EAT8
names: Caution
names: Function
names: Similarity
messages: Belongs to the UbiX/PAD1 family.
messages: Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

211586:SO RS01030
gene id: 211586:SO_RS01030
uniprot id: Q8EK81
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

211586:SO RS18340
gene id: 211586:SO_RS18340
uniprot id: Q8EAG2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

211586:SO RS18045
gene id: 211586:SO_RS18045
uniprot id: Q8CMJ3
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

211586:SO RS00495
gene id: 211586:SO_RS00495
uniprot id: Q8EKJ0
names: Cofactor
names: Function
messages: Binds 4 [4Fe-4S] clusters per subunit.
messages: The beta chain is an electron transfer unit containing 4 cysteine clusters involved in the formation of iron-sulfur centers.

211586:SO RS15770
gene id: 211586:SO_RS15770
uniprot id: Q8EBW6
names: Similarity
messages: Belongs to the CFA/CMAS family.

211586:SO RS19855
gene id: 211586:SO_RS19855
uniprot id: Q8E9J4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ApbE family.
messages: Cell inner membrane
messages: Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein.
messages: Magnesium. Can also use manganese.

211586:SO RS17760
gene id: 211586:SO_RS17760
uniprot id: Q8EAS8
names: Subcellular Location Annotation
messages: Membrane

211586:SO RS07610
gene id: 211586:SO_RS07610
uniprot id: Q8EGF7
names: Similarity
messages: Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family.

211586:SO RS07920
gene id: 211586:SO_RS07920
uniprot id: Q8EG85
names: Subcellular Location Annotation
messages: Cytoplasm

211586:SO RS00525
gene id: 211586:SO_RS00525
uniprot id: Q8EKI6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FdhD family.
messages: Cytoplasm
messages: Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH.

211586:SO RS01720
gene id: 211586:SO_RS01720
uniprot id: Q8EJU8
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

211586:SO RS06140
gene id: 211586:SO_RS06140
uniprot id: Q8EHA4
names: Similarity
messages: Belongs to the glutamate synthase family.

211586:SO RS07570
gene id: 211586:SO_RS07570
uniprot id: Q8EGG5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
messages: Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
messages: Homotrimer.

211586:SO RS15635
gene id: 211586:SO_RS15635
uniprot id: Q8EBZ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

211586:SO RS02485
gene id: 211586:SO_RS02485
uniprot id: Q8EJE5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscL family.
messages: Cell inner membrane
messages: Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
messages: Homopentamer.

211586:SO RS01180
gene id: 211586:SO_RS01180
uniprot id: Q8EK53
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

211586:SO RS01640
gene id: 211586:SO_RS01640
uniprot id: Q8EJW3
names: Activity Regulation
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Inhibited by ferricyanide and EDTA.
messages: Involved in the catabolism of short chain fatty acids (SCFA) via the 2-methylcitrate cycle II (propionate degradation route). In vivo under anaerobic conditions, AcnD catalyzes the stereospecific dehydration of (2S,3S)-methylcitrate (2-MC) to yield the trans isomer of 2-methyl-aconitate (2-MCA). AcnD can also accept citrate and cis-aconitate, but with a lower efficiency. 2-methylisocitrate and isocitrate are not substrates.
messages: Together with PrpF, able to restore the growth of prpD mutant on propionate.

211586:SO RS18170
gene id: 211586:SO_RS18170
uniprot id: Q8EAJ9
names: Function
names: Similarity
messages: Acts on ADP-mannose and ADP-glucose as well as ADP-ribose. Prevents glycogen biosynthesis. The reaction catalyzed by this enzyme is a limiting step of the gluconeogenic process.
messages: Belongs to the Nudix hydrolase family. NudF subfamily.

211586:SO RS17215
gene id: 211586:SO_RS17215
uniprot id: Q8EB44
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

211586:SO RS06905
gene id: 211586:SO_RS06905
uniprot id: Q8EGV5
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

211586:SO RS12060
gene id: 211586:SO_RS12060
uniprot id: Q8EDX4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uridine kinase family.
messages: Cytoplasm

211586:SO RS21940
gene id: 211586:SO_RS21940
uniprot id: Q8E8E5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

211586:SO RS05410
gene id: 211586:SO_RS05410
uniprot id: Q8EHP6
names: Similarity
messages: Belongs to the DNA polymerase HolA subunit family.

211586:SO RS19455
gene id: 211586:SO_RS19455
uniprot id: Q8E9R4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell inner membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

211586:SO RS15675
gene id: 211586:SO_RS15675
uniprot id: Q8EBY2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

211586:SO RS07675
gene id: 211586:SO_RS07675
uniprot id: Q8EGE1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NapF family.
messages: Could be involved in the maturation of NapA, the catalytic subunit of the periplasmic nitrate reductase, before its export into the periplasm.
messages: Cytoplasm
messages: Interacts with the cytoplasmic NapA precursor.

211586:SO RS16325
gene id: 211586:SO_RS16325
uniprot id: Q8EBL8
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

211586:SO RS00535
gene id: 211586:SO_RS00535
uniprot id: Q8EKI4
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

211586:SO RS18900
gene id: 211586:SO_RS18900
uniprot id: Q8EA37
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methylthiotransferase family. RimO subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein uS12.
messages: Cytoplasm

211586:SO RS09695
gene id: 211586:SO_RS09695
uniprot id: Q8EF78
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family. OpgH subfamily.
messages: Cell inner membrane
messages: Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs).

211586:SO RS00795
gene id: 211586:SO_RS00795
uniprot id: Q8EKC3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP J family.
messages: Cell inner membrane
messages: Membrane

211586:SO RS17545
gene id: 211586:SO_RS17545
uniprot id: Q8EAX6
names: Similarity
messages: Belongs to the PspA/IM30 family.

211586:SO RS08405
gene id: 211586:SO_RS08405
uniprot id: Q8EFY7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

211586:SO RS13080
gene id: 211586:SO_RS13080
uniprot id: Q8EDD8
names: Subcellular Location Annotation
messages: Membrane

211586:SO RS21025
gene id: 211586:SO_RS21025
uniprot id: Q8E8X5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

211586:SO RS17790
gene id: 211586:SO_RS17790
uniprot id: Q8EAS2
names: Subcellular Location Annotation
messages: Membrane

211586:SO RS18925
gene id: 211586:SO_RS18925
uniprot id: Q8EA30
names: Similarity
messages: Belongs to the UPF0307 family.

211586:SO RS09295
gene id: 211586:SO_RS09295
uniprot id: Q8EFF7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the heat shock protein 90 family.
messages: Cytoplasm
messages: Homodimer.
messages: Molecular chaperone. Has ATPase activity.

211586:SO RS08835
gene id: 211586:SO_RS08835
uniprot id: Q8EFQ7
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

211586:SO RS06125
gene id: 211586:SO_RS06125
uniprot id: Q8EHA8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobD/CbiB family.
messages: Cell membrane
messages: Membrane

211586:SO RS10500
gene id: 211586:SO_RS10500
uniprot id: Q8EES8
names: Function
names: Similarity
messages: Belongs to the TrhO family.
messages: Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs.

211586:SO RS15705
gene id: 211586:SO_RS15705
uniprot id: Q8EBX6
names: Function
names: Similarity
messages: Belongs to the Fe(2+)-trafficking protein family.
messages: Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes.

211586:SO RS20715
gene id: 211586:SO_RS20715
uniprot id: Q8E928
names: Subcellular Location Annotation
messages: Membrane

211586:SO RS11015
gene id: 211586:SO_RS11015
uniprot id: Q8EEI0
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS1 family.
messages: Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence.

211586:SO RS04815
gene id: 211586:SO_RS04815
uniprot id: Q8EI19
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

211586:SO RS21515
gene id: 211586:SO_RS21515
uniprot id: Q8E8N1
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family. GreB subfamily.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length.

211586:SO RS11560
gene id: 211586:SO_RS11560
uniprot id: Q8EE78
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrB/RnfD family.
messages: Cell inner membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

211586:SO RS11545
gene id: 211586:SO_RS11545
uniprot id: Q8EE81
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell inner membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

211586:SO RS18615
gene id: 211586:SO_RS18615
uniprot id: Q8EAA4
names: Subcellular Location Annotation
messages: Membrane

211586:SO RS12825
gene id: 211586:SO_RS12825
uniprot id: Q8EDI0
names: Similarity
messages: Belongs to the glucose-6-phosphate 1-epimerase family.

211586:SO RS11095
gene id: 211586:SO_RS11095
uniprot id: Q8EEG3
names: Similarity
messages: In the N-terminal section; belongs to the NADH:flavin oxidoreductase/NADH oxidase family.

211586:SO RS02210
gene id: 211586:SO_RS02210
uniprot id: Q8EJK0
names: Subcellular Location Annotation
messages: Membrane

211586:SO RS00160
gene id: 211586:SO_RS00160
uniprot id: Q8EKQ8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

211586:SO RS02405
gene id: 211586:SO_RS02405
uniprot id: Q8EJG4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0718 family.
messages: Cell membrane
messages: Membrane

211586:SO RS10960
gene id: 211586:SO_RS10960
uniprot id: Q8EEJ1
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-II family.

211586:SO RS12595
gene id: 211586:SO_RS12595
uniprot id: Q8EDL5
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell inner membrane

211586:SO RS11865
gene id: 211586:SO_RS11865
uniprot id: Q8EE13
names: Function
names: Similarity
names: Subunit
messages: ATPase required for the correct placement of the division site. Cell division inhibitors MinC and MinD act in concert to form an inhibitor capable of blocking formation of the polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings.
messages: Belongs to the ParA family. MinD subfamily.
messages: Interacts with MinC and FtsZ.

211586:SO RS01340
gene id: 211586:SO_RS01340
uniprot id: Q8EK28
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.

211586:SO RS02235
gene id: 211586:SO_RS02235
uniprot id: Q8EJJ6
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

211586:SO RS06235
gene id: 211586:SO_RS06235
uniprot id: Q8EH85
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RseB family.
messages: Periplasm

211586:SO RS10805
gene id: 211586:SO_RS10805
uniprot id: Q8EEM3
names: Similarity
messages: Belongs to the universal stress protein A family.

211586:SO RS20995
gene id: 211586:SO_RS20995
uniprot id: Q8E8Y1
names: Subcellular Location Annotation
messages: Membrane

211586:SO RS07100
gene id: 211586:SO_RS07100
uniprot id: Q8EGR6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MotA family.
messages: Membrane

211586:SO RS02860
gene id: 211586:SO_RS02860
uniprot id: Q8EJ70
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

211586:SO RS01910
gene id: 211586:SO_RS01910
uniprot id: Q8EJR5
names: Function
messages: Membrane-anchoring subunit of succinate dehydrogenase (SDH).

211586:SO RS17010
gene id: 211586:SO_RS17010
uniprot id: Q8EB90
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

211586:SO RS02865
gene id: 211586:SO_RS02865
uniprot id: Q8CX50
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Monomer.

211586:SO RS03920
gene id: 211586:SO_RS03920
uniprot id: Q8EIK5
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SprT family.
messages: Binds 1 zinc ion.
messages: Cytoplasm

211586:SO RS05620
gene id: 211586:SO_RS05620
uniprot id: K4PSE0
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

211586:SO RS04895
gene id: 211586:SO_RS04895
uniprot id: Q8EI01
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
messages: Membrane

211586:SO RS01225
gene id: 211586:SO_RS01225
uniprot id: Q8EK47
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

211586:SO RS14680
gene id: 211586:SO_RS14680
uniprot id: Q8ECJ1
names: Similarity
messages: Belongs to the tRNA methyltransferase O family.

211586:SO RS22800
gene id: 211586:SO_RS22800
uniprot id: Q8CMJ3
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

211586:SO RS14900
gene id: 211586:SO_RS14900
uniprot id: Q8ECE8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RfaH family.
messages: Enhances distal genes transcription elongation in a specialized subset of operons that encode extracytoplasmic components.
messages: Interacts with both the nontemplate DNA and the RNA polymerase (RNAP).

211586:SO RS21290
gene id: 211586:SO_RS21290
uniprot id: Q8E8S8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoH subfamily.
messages: Cytoplasm
messages: Interacts with the RNA polymerase core enzyme.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes.

211586:SO RS07930
gene id: 211586:SO_RS07930
uniprot id: Q8EG83
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Membrane

211586:SO RS09640
gene id: 211586:SO_RS09640
uniprot id: Q8EF89
names: Similarity
messages: Belongs to the peptidase A31 family.

211586:SO RS05905
gene id: 211586:SO_RS05905
uniprot id: Q8EHF0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

211586:SO RS02540
gene id: 211586:SO_RS02540
uniprot id: Q8EJD3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arsenical resistance-3 (ACR3) (TC 2.A.59) family.
messages: Cell membrane
messages: Membrane

211586:SO RS07935
gene id: 211586:SO_RS07935
uniprot id: Q8EG82
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family.
messages: Cell inner membrane
messages: Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system.
messages: The complex is composed of two ATP-binding proteins (PstB), two transmembrane proteins (PstC and PstA) and a solute-binding protein (PstS).

211586:SO RS06155
gene id: 211586:SO_RS06155
uniprot id: Q8EHA1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

211586:SO RS10125
gene id: 211586:SO_RS10125
uniprot id: Q8EF03
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

211586:SO RS07110
gene id: 211586:SO_RS07110
uniprot id: Q8EGR4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThiI family.
messages: Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.
messages: Cytoplasm

211586:SO RS19140
gene id: 211586:SO_RS19140
uniprot id: Q8E9Y2
names: Subcellular Location Annotation
messages: Membrane

211586:SO RS08995
gene id: 211586:SO_RS08995
uniprot id: Q8EFM2
names: Subcellular Location Annotation
messages: Membrane

211586:SO RS14780
gene id: 211586:SO_RS14780
uniprot id: Q8ECH1
names: Similarity
messages: Belongs to the polysaccharide synthase family.

211586:SO RS15125
gene id: 211586:SO_RS15125
uniprot id: Q8ECA3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Flagellum-specific muramidase which hydrolyzes the peptidoglycan layer to assemble the rod structure in the periplasmic space.
messages: In the C-terminal section; belongs to the glycosyl hydrolase 73 family.
messages: In the N-terminal section; belongs to the FlgJ family.
messages: Periplasm

211586:SO RS16080
gene id: 211586:SO_RS16080
uniprot id: Q8EBR0
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Component of the RNA degradosome, which is a multiprotein complex involved in RNA processing and mRNA degradation.
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

211586:SO RS08685
gene id: 211586:SO_RS08685
uniprot id: Q8EFT7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

211586:SO RS05130
gene id: 211586:SO_RS05130
uniprot id: Q8EHV4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrF family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Cell inner membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: Membrane
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway.

211586:SO RS06430
gene id: 211586:SO_RS06430
uniprot id: Q8EH47
names: Similarity
messages: Belongs to the DEAD box helicase family.

211586:SO RS12900
gene id: 211586:SO_RS12900
uniprot id: Q8EDG6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase E/G family. RNase E subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per homotetramer.
messages: Cell inner membrane
messages: Component of the RNA degradosome, which is a multiprotein complex involved in RNA processing and mRNA degradation. Within the RNA degradosome, RNase E assembles into a homotetramer formed by a dimer of dimers.
messages: Cytoplasm
messages: Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs.

211586:SO RS21970
gene id: 211586:SO_RS21970
uniprot id: Q8E8D9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FPG family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
messages: Monomer.

211586:SO RS15595
gene id: 211586:SO_RS15595
uniprot id: Q8EC00
names: Similarity
messages: Belongs to the SUI1 family.

211586:SO RS19940
gene id: 211586:SO_RS19940
uniprot id: Q8E9I0
names: Subcellular Location Annotation
messages: Cytoplasm

211586:SO RS16460
gene id: 211586:SO_RS16460
uniprot id: Q8CMJ3
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

211586:SO RS01065
gene id: 211586:SO_RS01065
uniprot id: Q8EK74
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

211586:SO RS10400
gene id: 211586:SO_RS10400
uniprot id: Q8EEU7
names: Similarity
messages: Belongs to the HesB/IscA family.

211586:SO RS10325
gene id: 211586:SO_RS10325
uniprot id: Q8EEW2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 3 family. NagZ subfamily.
messages: Cytoplasm
messages: Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide-linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N-acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides.

211586:SO RS15275
gene id: 211586:SO_RS15275
uniprot id: Q8EC73
names: Similarity
messages: Belongs to the polysaccharide synthase family.

211586:SO RS18015
gene id: 211586:SO_RS18015
uniprot id: Q8EAM8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DsbB family. DsbI subfamily.
messages: Cell inner membrane
messages: Interacts with DsbL.
messages: Required for disulfide bond formation in some proteins. Part of a redox system composed of DsbI and DsbL that mediates formation of an essential disulfide bond in AssT (By similarity).

211586:SO RS09575
gene id: 211586:SO_RS09575
uniprot id: Q8EFA2
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

211586:SO RS01135
gene id: 211586:SO_RS01135
uniprot id: Q8EK62
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

211586:SO RS08800
gene id: 211586:SO_RS08800
uniprot id: Q8EFR5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 6-phosphogluconate dehydrogenase family.
messages: Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
messages: Homodimer.

211586:SO RS16160
gene id: 211586:SO_RS16160
uniprot id: Q8EBQ2
names: Subcellular Location Annotation
messages: Cell inner membrane

211586:SO RS06320
gene id: 211586:SO_RS06320
uniprot id: Q8EH69
names: Function
names: Similarity
messages: Belongs to the class-I DAHP synthase family.
messages: Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP).

211586:SO RS00730
gene id: 211586:SO_RS00730
uniprot id: Q8EKD8
names: Subcellular Location Annotation
messages: Membrane

211586:SO RS19735
gene id: 211586:SO_RS19735
uniprot id: Q8E9L4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase PH family.
messages: Homohexameric ring arranged as a trimer of dimers.
messages: Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.

211586:SO RS15855
gene id: 211586:SO_RS15855
uniprot id: Q8CMJ3
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

211586:SO RS00500
gene id: 211586:SO_RS00500
uniprot id: Q8EKI9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the formate dehydrogenase gamma subunit family.
messages: Membrane

211586:SO RS21420
gene id: 211586:SO_RS21420
uniprot id: Q8E8Q0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SURF1 family.
messages: Cell membrane

211586:SO RS15135
gene id: 211586:SO_RS15135
uniprot id: Q8ECA1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
messages: Bacterial flagellum basal body
messages: Belongs to the FlgH family.
messages: Cell outer membrane
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod.

211586:SO RS12435
gene id: 211586:SO_RS12435
uniprot id: Q8EDQ0
names: Similarity
messages: Belongs to the myoviridae tail sheath protein family.

211586:SO RS15945
gene id: 211586:SO_RS15945
uniprot id: Q8EBS9
names: PTM
messages: Binds 1 heme group per subunit.

211586:SO RS21770
gene id: 211586:SO_RS21770
uniprot id: Q8E8I0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

211586:SO RS11670
gene id: 211586:SO_RS11670
uniprot id: Q8EE54
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

211586:SO RS15710
gene id: 211586:SO_RS15710
uniprot id: Q8EBX5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0312 family. Type 1 subfamily.
messages: Periplasm

211586:SO RS11845
gene id: 211586:SO_RS11845
uniprot id: Q8EE18
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

211586:SO RS04590
gene id: 211586:SO_RS04590
uniprot id: Q8EI69
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.

211586:SO RS21295
gene id: 211586:SO_RS21295
uniprot id: Q8E8S7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
messages: Cell inner membrane
messages: Forms a membrane-associated complex with FtsE.
messages: Membrane
messages: Part of the ABC transporter FtsEX involved in cellular division.

211586:SO RS05690
gene id: 211586:SO_RS05690
uniprot id: Q8EHJ8
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

211586:SO RS15155
gene id: 211586:SO_RS15155
uniprot id: Q8EC96
names: Function
names: Similarity
messages: Belongs to the FlgD family.
messages: Required for flagellar hook formation. May act as a scaffolding protein.

211586:SO RS14750
gene id: 211586:SO_RS14750
uniprot id: Q8ECH7
names: Cofactor
names: Disruption Phenotype
names: Domain
names: Function
names: Induction
names: Similarity
names: Subunit
messages: Antitoxin component of a type VII toxin-antitoxin (TA) system. Upon overexpression in situ or in E.coli neutralizes the effect of cognate toxin HepT (PubMed:26112399, PubMed:29555683, PubMed:33045733). Neutralization is mostly due to tri-AMPylation of toxin by this enzyme. Successively tri-AMPylates HepT on 'Tyr-104' (PubMed:33045733). Binds its own promoter, probably repressing its expression. The TA system confers plasmid stability in E.coli (PubMed:26112399).
messages: Belongs to the MntA antitoxin family.
messages: Binds 2 Mg(2+) per subunit.
messages: Expressed during exponential growth, part of the mntA-hepT operon. Under autocontrol by MntA.
messages: Forms a complex with cognate toxin HepT, may form a homodimer by itself (PubMed:26112399). Forms a heterooctamer with cognate toxin HEPN with stoichiometry HepT(6):MntA(2). The 2 MNT subunits do not contact each other in the heterooctamer, each contacts 3 HEPN subunits, blocking access to the toxin active site (PubMed:29555683).
messages: Has 2 alpha-helices that are important for interaction with cognate toxin HEPN; deletion of helix 2 (residues 52-65) or the C-terminus of helix 4 (residues 114-125) reduces antitoxin function about 100-fold, while deletion of the N-terminus of helix 4 (residues 98-113) reduces antitoxin function over 1000-fold.
messages: When mntA-hepT is deleted, has a sight reduction in swimming motility. This gene cannot be deleted when the hepT gene is intact.

211586:SO RS05985
gene id: 211586:SO_RS05985
uniprot id: P59251
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsY family.
messages: Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
messages: Cell inner membrane
messages: Probably interacts with PlsX.

211586:SO RS19585
gene id: 211586:SO_RS19585
uniprot id: Q8E9P3
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm

211586:SO RS00015
gene id: 211586:SO_RS00015
uniprot id: Q8CX52
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
messages: Binds 1 potassium ion per subunit.
messages: Cytoplasm
messages: Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.

211586:SO RS21385
gene id: 211586:SO_RS21385
uniprot id: Q8E8Q8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S24 family.
messages: Homodimer.
messages: Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.

211586:SO RS03895
gene id: 211586:SO_RS03895
uniprot id: Q8EIL1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methyltransferase superfamily. RsmC family.
messages: Cytoplasm
messages: Monomer.
messages: Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle.

211586:SO RS11000
gene id: 211586:SO_RS11000
uniprot id: Q8EEI3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LapB family.
messages: Cell inner membrane
messages: Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane.

211586:SO RS04455
gene id: 211586:SO_RS04455
uniprot id: Q8EI96
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DEAD box helicase family. SrmB subfamily.
messages: Cytoplasm
messages: DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit at low temperature. Exhibits RNA-stimulated ATP hydrolysis and RNA unwinding activity.
messages: Interacts with the 50S ribosomal subunit.

211586:SO RS15020
gene id: 211586:SO_RS15020
uniprot id: Q8ECC3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliN/MopA/SpaO family.
messages: Cell membrane
messages: FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
messages: Membrane

211586:SO RS23140
gene id: 211586:SO_RS23140
uniprot id: Q8E832
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane OOP (TC 1.B.6) superfamily. OmpA family.
messages: Cell outer membrane
messages: Membrane

211586:SO RS22355
gene id: 211586:SO_RS22355
uniprot id: Q8E874
names: Subcellular Location Annotation
messages: Membrane

211586:SO RS00640
gene id: 211586:SO_RS00640
uniprot id: Q8EKF9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. METTL16/RlmF family.
messages: Cytoplasm
messages: Specifically methylates the adenine in position 1618 of 23S rRNA.

211586:SO RS00270
gene id: 211586:SO_RS00270
uniprot id: Q8EKP0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecB family.
messages: Cytoplasm
messages: Homotetramer, a dimer of dimers. One homotetramer interacts with 1 SecA dimer.
messages: One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA.

211586:SO RS02800
gene id: 211586:SO_RS02800
uniprot id: K4PW03
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Prokaryotic type I sub-subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
messages: Cell membrane
messages: Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The autoendoproteolytic cleavage occurs by a canonical serine protease mechanism, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain. During this reaction, the Ser that is part of the protease active site of the proenzyme becomes the pyruvoyl prosthetic group, which constitutes an essential element of the active site of the mature decarboxylase.

211586:SO RS15480
gene id: 211586:SO_RS15480
uniprot id: Q8EC25
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DoxX family.
messages: Membrane

211586:SO RS18140
gene id: 211586:SO_RS18140
uniprot id: Q8EAK5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 1 subfamily.
messages: Cell membrane
messages: Heterotetramer composed of ParC and ParE.
messages: Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.

211586:SO RS05385
gene id: 211586:SO_RS05385
uniprot id: Q8EHQ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEDS family. MrdB/RodA subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Peptidoglycan polymerase that is essential for cell wall elongation.

211586:SO RS08915
gene id: 211586:SO_RS08915
uniprot id: Q8EFP0
names: Function
names: Similarity
messages: Belongs to the alpha-ketoglutarate dehydrogenase family.
messages: E1 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the decarboxylation of 2-oxoglutarate, the first step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).

211586:SO RS13225
gene id: 211586:SO_RS13225
uniprot id: Q8EDB1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gmhB family.
messages: Cytoplasm

211586:SO RS16635
gene id: 211586:SO_RS16635
uniprot id: Q8EBF9
names: Similarity
messages: Belongs to the glutamate--cysteine ligase type 1 family. Type 1 subfamily.

211586:SO RS00140
gene id: 211586:SO_RS00140
uniprot id: Q8EKR2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TrkH potassium transport family.
messages: Cell inner membrane
messages: Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA.
messages: Membrane

211586:SO RS15190
gene id: 211586:SO_RS15190
uniprot id: Q8EC89
names: Function
names: Similarity
messages: Belongs to the FlgN family.
messages: Required for the efficient initiation of filament assembly.

211586:SO RS19115
gene id: 211586:SO_RS19115
uniprot id: Q8E9Y7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

211586:SO RS08110
gene id: 211586:SO_RS08110
uniprot id: Q8EG41
names: Similarity
messages: Belongs to the group II decarboxylase family.

211586:SO RS04975
gene id: 211586:SO_RS04975
uniprot id: Q8EHY4
names: Similarity
messages: Belongs to the catalase family.

211586:SO RS14845
gene id: 211586:SO_RS14845
uniprot id: Q8ECF9
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

211586:SO RS19520
gene id: 211586:SO_RS19520
uniprot id: Q8E9Q5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell inner membrane
messages: Cytoplasm
messages: May bind 1 zinc ion per subunit.
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

211586:SO RS15115
gene id: 211586:SO_RS15115
uniprot id: Q8ECA4
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Secreted

211586:SO RS08535
gene id: 211586:SO_RS08535
uniprot id: Q8EFW2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCF family. Uup subfamily.
messages: Cytoplasm
messages: Probably plays a role in ribosome assembly or function. May be involved in resolution of branched DNA intermediates that result from template switching in postreplication gaps. Binds DNA and has ATPase activity.

211586:SO RS07000
gene id: 211586:SO_RS07000
uniprot id: Q8EGT3
names: Similarity
messages: Belongs to the bleomycin resistance protein family.

211586:SO RS08235
gene id: 211586:SO_RS08235
uniprot id: Q8EG20
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

211586:SO RS01900
gene id: 211586:SO_RS01900
uniprot id: Q8EJR7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. PrmA family.
messages: Cytoplasm
messages: Methylates ribosomal protein L11.

211586:SO RS21875
gene id: 211586:SO_RS21875
uniprot id: Q8CMJ3
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

211586:SO RS08830
gene id: 211586:SO_RS08830
uniprot id: Q8EFQ8
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

211586:SO RS12065
gene id: 211586:SO_RS12065
uniprot id: Q8EDX3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.
messages: In the C-terminal section; belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: In the N-terminal section; belongs to the MIP18 family.

211586:SO RS16780
gene id: 211586:SO_RS16780
uniprot id: Q8EBD7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetate uptake transporter (AceTr) (TC 2.A.96) family.
messages: Membrane

211586:SO RS10745
gene id: 211586:SO_RS10745
uniprot id: Q8CMJ3
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

211586:SO RS11905
gene id: 211586:SO_RS11905
uniprot id: Q8EE04
names: Similarity
messages: Belongs to the KAE1 / TsaD family. TsaB subfamily.

211586:SO RS04545
gene id: 211586:SO_RS04545
uniprot id: Q8EI78
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

211586:SO RS12865
gene id: 211586:SO_RS12865
uniprot id: Q8EDH1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

211586:SO RS00340
gene id: 211586:SO_RS00340
uniprot id: Q8EKM5
names: Similarity
messages: In the C-terminal section; belongs to the transpeptidase family.
messages: In the N-terminal section; belongs to the glycosyltransferase 51 family.

211586:SO RS08825
gene id: 211586:SO_RS08825
uniprot id: Q8EFQ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MenA family. Type 1 subfamily.
messages: Cell inner membrane
messages: Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK).
messages: Membrane

211586:SO RS06165
gene id: 211586:SO_RS06165
uniprot id: Q8EH99
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MutH family.
messages: Cytoplasm
messages: Sequence-specific endonuclease that cleaves unmethylated GATC sequences. It is involved in DNA mismatch repair.

211586:SO RS21245
gene id: 211586:SO_RS21245
uniprot id: Q8E8T4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TPP enzyme family. MenD subfamily.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC).
messages: Homodimer.

211586:SO RS05600
gene id: 211586:SO_RS05600
uniprot id: Q8EHL7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

211586:SO RS21300
gene id: 211586:SO_RS21300
uniprot id: Q8E8S6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Homodimer. Forms a membrane-associated complex with FtsX.
messages: Part of the ABC transporter FtsEX involved in cellular division. Important for assembly or stability of the septal ring.

211586:SO RS04135
gene id: 211586:SO_RS04135
uniprot id: Q8EIF9
names: Similarity
messages: Belongs to the AB hydrolase superfamily. AB hydrolase 4 family.

211586:SO RS01905
gene id: 211586:SO_RS01905
uniprot id: Q8EJR6
names: Function
messages: Membrane-anchoring subunit of succinate dehydrogenase (SDH).

211586:SO RS16850
gene id: 211586:SO_RS16850
uniprot id: Q8EBC1
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

211586:SO RS21720
gene id: 211586:SO_RS21720
uniprot id: Q8E8J1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the zinc-containing alcohol dehydrogenase family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the NAD(+)-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate.
messages: Cytoplasm
messages: Homotetramer.

211586:SO RS00465
gene id: 211586:SO_RS00465
uniprot id: Q8EKJ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family.
messages: Membrane

211586:SO RS06645
gene id: 211586:SO_RS06645
uniprot id: Q8EH02
names: Function
messages: Electron transfer subunit of the terminal reductase during anaerobic growth on various sulfoxide and N-oxide compounds.

211586:SO RS21440
gene id: 211586:SO_RS21440
uniprot id: Q8E8P6
names: Similarity
messages: Belongs to the SCO1/2 family.

211586:SO RS00260
gene id: 211586:SO_RS00260
uniprot id: P59175
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the BPG-independent phosphoglycerate mutase family.
messages: Binds 2 manganese ions per subunit.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: Monomer.

211586:SO RS17180
gene id: 211586:SO_RS17180
uniprot id: Q8EB51
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

211586:SO RS11405
gene id: 211586:SO_RS11405
uniprot id: Q8EEA1
names: Similarity
messages: Belongs to the KHG/KDPG aldolase family.

211586:SO RS17320
gene id: 211586:SO_RS17320
uniprot id: Q8EB21
names: Similarity
messages: Belongs to the nitroreductase family.

211586:SO RS17905
gene id: 211586:SO_RS17905
uniprot id: Q8EAQ3
names: Similarity
messages: Belongs to the peptidase M13 family.

211586:SO RS17810
gene id: 211586:SO_RS17810
uniprot id: Q8CMJ3
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

211586:SO RS14305
gene id: 211586:SO_RS14305
uniprot id: Q8ECQ2
names: Function
names: Similarity
messages: Belongs to the peptidase M16 family.
messages: Endopeptidase that degrades small peptides of less than 7 kDa, such as glucagon and insulin.

211586:SO RS05125
gene id: 211586:SO_RS05125
uniprot id: Q8EHV5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell inner membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: Membrane
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

211586:SO RS06865
gene id: 211586:SO_RS06865
uniprot id: Q8EGW5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamE family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

211586:SO RS16065
gene id: 211586:SO_RS16065
uniprot id: Q8EBR3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IspF family.
messages: Binds 1 divalent metal cation per subunit.
messages: Homotrimer.
messages: Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).

211586:SO RS19545
gene id: 211586:SO_RS19545
uniprot id: Q8E9Q0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.
messages: Cell inner membrane
messages: Self-interacts. Interacts with FtsZ.

211586:SO RS06570
gene id: 211586:SO_RS06570
uniprot id: Q8EH17
names: Similarity
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.

211586:SO RS08635
gene id: 211586:SO_RS08635
uniprot id: Q8EFU7
names: Similarity
messages: Belongs to the CvfB family.

211586:SO RS10885
gene id: 211586:SO_RS10885
uniprot id: Q8EEK8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Bcr/CmlA family.
messages: Cell inner membrane
messages: Membrane

211586:SO RS07085
gene id: 211586:SO_RS07085
uniprot id: Q8EGR9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

211586:SO RS15270
gene id: 211586:SO_RS15270
uniprot id: Q8EC74
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

211586:SO RS07220
gene id: 211586:SO_RS07220
uniprot id: Q8EGP1
names: Function
messages: This protein is a positive regulator for the phosphate regulon. Transcription of this operon is positively regulated by PhoB and PhoR when phosphate is limited.

211586:SO RS12545
gene id: 211586:SO_RS12545
uniprot id: Q8EDM5
names: Subcellular Location Annotation
messages: Membrane

211586:SO RS22860
gene id: 211586:SO_RS22860
uniprot id: Q8E804
names: Similarity
messages: Belongs to the UPF0319 family.

211586:SO RS11505
gene id: 211586:SO_RS11505
uniprot id: Q8EE84
names: Subcellular Location Annotation
messages: Membrane

211586:SO RS00350
gene id: 211586:SO_RS00350
uniprot id: Q8EKM3
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

211586:SO RS11155
gene id: 211586:SO_RS11155
uniprot id: Q8EEE9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp).
messages: Cytoplasm
messages: Homodimer.

211586:SO RS13140
gene id: 211586:SO_RS13140
uniprot id: Q8EDC4
names: Similarity
messages: Belongs to the DEAD box helicase family.

211586:SO RS19575
gene id: 211586:SO_RS19575
uniprot id: Q8E9P5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell inner membrane

211586:SO RS14235
gene id: 211586:SO_RS14235
uniprot id: K4PSU2
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

211586:SO RS22215
gene id: 211586:SO_RS22215
uniprot id: Q8CM48
names: Similarity
messages: Belongs to the transposase 7 family.

211586:SO RS17505
gene id: 211586:SO_RS17505
uniprot id: Q8CX39
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

211586:SO RS05880
gene id: 211586:SO_RS05880
uniprot id: Q8EHF4
names: Similarity
messages: Belongs to the glutamine synthetase family.

211586:SO RS21210
gene id: 211586:SO_RS21210
uniprot id: Q8E8U1
names: Subcellular Location Annotation
messages: Membrane

211586:SO RS01645
gene id: 211586:SO_RS01645
uniprot id: Q8EJW2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the citrate synthase family.
messages: Homodimer.
messages: Involved in the catabolism of short chain fatty acids (SCFA) via the tricarboxylic acid (TCA)(acetyl degradation route) and via the 2-methylcitrate cycle II (propionate degradation route). Catalyzes the Claisen condensation of propionyl-CoA and oxaloacetate (OAA) to yield 2-methylcitrate (2-MC) and CoA (PubMed:14702315). Catalyzes the condensation of oxaloacetate with acetyl-CoA (By similarity).

211586:SO RS08010
gene id: 211586:SO_RS08010
uniprot id: Q8EG63
names: Disruption Phenotype
names: Function
names: Similarity
messages: Belongs to the 3-beta-HSD family.
messages: Deletion of the entire oleABCD gene cluster leads to the complete absence of nonpolar extractable products. The oleABCD deletion strain shows a significantly longer lag phase than the wild-type strain when shifted to a lower temperature.
messages: Involved in olefin biosynthesis (PubMed:20418444). Catalyzes the reversible stereospecific NADPH-dependent reduction of 2-alkyl-3-oxoalkanoic acids to 2-alkyl-3-hydroxyalkanoic acids (By similarity). The S.oneidensis oleABCD genes produce 3,6,9,12,15,19,22,25,28-hentriacontanonaene, which may aid the cells in adapting to a sudden drop in temperature (PubMed:20418444).

211586:SO RS04015
gene id: 211586:SO_RS04015
uniprot id: Q8EII3
names: Subcellular Location Annotation
messages: Membrane

211586:SO RS13265
gene id: 211586:SO_RS13265
uniprot id: Q8EDA2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family.
messages: Periplasm

211586:SO RS11495
gene id: 211586:SO_RS11495
uniprot id: Q8EE87
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.
messages: Binds 1 S-adenosyl-L-methionine per subunit.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

211586:SO RS10195
gene id: 211586:SO_RS10195
uniprot id: Q8EEZ1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

211586:SO RS15120
gene id: 211586:SO_RS15120
uniprot id: K4PSJ4
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the flagella basal body rod proteins family.
messages: Secreted

211586:SO RS02065
gene id: 211586:SO_RS02065
uniprot id: Q8EJN4
names: Similarity
messages: Belongs to the peptidase M13 family.

211586:SO RS18440
gene id: 211586:SO_RS18440
uniprot id: Q8EAE5
names: Function
names: Similarity
messages: Belongs to the sigma-54 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

211586:SO RS10750
gene id: 211586:SO_RS10750
uniprot id: Q8EEN3
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

211586:SO RS00635
gene id: 211586:SO_RS00635
uniprot id: Q8EKG1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliL family.
messages: Cell inner membrane
messages: Controls the rotational direction of flagella during chemotaxis.
messages: Membrane

211586:SO RS11370
gene id: 211586:SO_RS11370
uniprot id: Q8EEA9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Activates KDO8N (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in the Shewanella genus.
messages: Belongs to the KdsB family.
messages: Cytoplasm

211586:SO RS21990
gene id: 211586:SO_RS21990
uniprot id: Q8E8D5
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Monomer.

211586:SO RS00070
gene id: 211586:SO_RS00070
uniprot id: Q8EKS6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

211586:SO RS10680
gene id: 211586:SO_RS10680
uniprot id: Q8EEP8
names: Domain
names: Function
names: Similarity
messages: Adopts a GT-B fold and acts as an inverting enzyme that converts the beta-configuration in the dTDP-beta-L-rhamnose donor to the alpha configuration in the N-linked (Rha) arginine product.
messages: Belongs to the glycosyltransferase 104 family.
messages: Protein-arginine rhamnosyltransferase that catalyzes the transfer of a single rhamnose to elongation factor P (EF-P) on 'Lys-32', a modification required for EF-P-dependent rescue of polyproline stalled ribosomes.

211586:SO RS03405
gene id: 211586:SO_RS03405
uniprot id: Q8EIW0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

211586:SO RS02950
gene id: 211586:SO_RS02950
uniprot id: Q8EJ53
names: Similarity
messages: Belongs to the 2-oxoadipate dioxygenase/decarboxylase family.

211586:SO RS16210
gene id: 211586:SO_RS16210
uniprot id: Q8EBP2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DHBP synthase family.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Homodimer.
messages: In the C-terminal section; belongs to the GTP cyclohydrolase II family.
messages: In the N-terminal section; belongs to the DHBP synthase family.

211586:SO RS05415
gene id: 211586:SO_RS05415
uniprot id: Q8EHP5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptE lipoprotein family.
messages: Cell outer membrane
messages: Component of the lipopolysaccharide transport and assembly complex. Interacts with LptD.
messages: Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane.

211586:SO RS15685
gene id: 211586:SO_RS15685
uniprot id: Q8EBY0
names: Similarity
names: Subunit
messages: Belongs to the glutaminase family.
messages: Homotetramer.

211586:SO RS01165
gene id: 211586:SO_RS01165
uniprot id: Q8EK56
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

211586:SO RS21840
gene id: 211586:SO_RS21840
uniprot id: Q8E8G5
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

211586:SO RS17765
gene id: 211586:SO_RS17765
uniprot id: Q8EAS7
names: Similarity
messages: Belongs to the UPF0234 family.

211586:SO RS21950
gene id: 211586:SO_RS21950
uniprot id: Q8E8E3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MobA family.
messages: Cytoplasm
messages: Monomer.
messages: The N-terminal domain determines nucleotide recognition and specific binding, while the C-terminal domain determines the specific binding to the target protein.
messages: Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor.

211586:SO RS05960
gene id: 211586:SO_RS05960
uniprot id: Q8EHE1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoD/SigA subfamily.
messages: Cytoplasm
messages: Interacts transiently with the RNA polymerase catalytic core.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.

211586:SO RS10705
gene id: 211586:SO_RS10705
uniprot id: Q8EEP2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SeqA family.
messages: Cytoplasm
messages: Homodimer. Polymerizes to form helical filaments.
messages: Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re-initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated.

211586:SO RS14860
gene id: 211586:SO_RS14860
uniprot id: Q8ECF6
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

211586:SO RS08890
gene id: 211586:SO_RS08890
uniprot id: Q8EFP4
names: Similarity
messages: Belongs to the citrate synthase family.

211586:SO RS17140
gene id: 211586:SO_RS17140
uniprot id: Q8EB59
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. Heme (hemin) importer (TC 3.A.1.14.5) family.
messages: Cell inner membrane
messages: Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system.
messages: The complex is composed of two ATP-binding proteins (HmuV), two transmembrane proteins (HmuU) and a solute-binding protein (HmuT).

211586:SO RS07075
gene id: 211586:SO_RS07075
uniprot id: Q8EGS1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.

211586:SO RS10580
gene id: 211586:SO_RS10580
uniprot id: Q8EER3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsK/SpoIIIE/SftA family.
messages: Cell inner membrane
messages: Consists of an N-terminal domain, which is sufficient for the localization to the septal ring and is required for cell division, followed by a linker domain, and a C-terminal domain, which forms the translocation motor involved in chromosome segregation. The C-terminal domain can be further subdivided into alpha, beta and gamma subdomains. The alpha and beta subdomains multimerise to produce a hexameric ring, contain the nucleotide binding motif and form the DNA pump. The gamma subdomain is a regulatory subdomain that controls translocation of DNA by recognition of KOPS motifs and interacts with XerD recombinase (By similarity).
messages: Essential cell division protein that coordinates cell division and chromosome segregation. The N-terminus is involved in assembly of the cell-division machinery. The C-terminus functions as a DNA motor that moves dsDNA in an ATP-dependent manner towards the dif recombination site, which is located within the replication terminus region. Translocation stops specifically at Xer-dif sites, where FtsK interacts with the Xer recombinase, allowing activation of chromosome unlinking by recombination. FtsK orienting polar sequences (KOPS) guide the direction of DNA translocation. FtsK can remove proteins from DNA as it translocates, but translocation stops specifically at XerCD-dif site, thereby preventing removal of XerC and XerD from dif (By similarity).
messages: Homohexamer. Forms a ring that surrounds DNA (By similarity).

211586:SO RS21285
gene id: 211586:SO_RS21285
uniprot id: Q8CME4
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

211586:SO RS08625
gene id: 211586:SO_RS08625
uniprot id: Q8EFU9
names: Subcellular Location Annotation
messages: Membrane

211586:SO RS19885
gene id: 211586:SO_RS19885
uniprot id: Q8E9I8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family.
messages: Cell inner membrane
messages: Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system.
messages: The complex is composed of two ATP-binding proteins (PstB), two transmembrane proteins (PstC and PstA) and a solute-binding protein (PstS).

211586:SO RS07540
gene id: 211586:SO_RS07540
uniprot id: Q8EGH1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with (2E,6E)-farnesyl diphosphate (E,E-FPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E,38E)-undecaprenyl diphosphate (di-trans,octa-cis-UPP). UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide.
messages: Homodimer.

211586:SO RS09070
gene id: 211586:SO_RS09070
uniprot id: Q8EFK9
names: Cofactor
names: Similarity
messages: Belongs to the 4HPPD family.
messages: Binds 1 Fe cation per subunit.

211586:SO RS10130
gene id: 211586:SO_RS10130
uniprot id: Q8EF02
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial diacylglycerol kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of sn-l,2-diacylglycerol (DAG) to phosphatidic acid. Involved in the recycling of diacylglycerol produced as a by-product during membrane-derived oligosaccharide (MDO) biosynthesis.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Mn(2+), Zn(2+), Cd(2+) and Co(2+) support activity to lesser extents.

211586:SO RS19165
gene id: 211586:SO_RS19165
uniprot id: Q8E9X6
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family.

211586:SO RS06195
gene id: 211586:SO_RS06195
uniprot id: Q8EH93
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
messages: Cell inner membrane
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

211586:SO RS04780
gene id: 211586:SO_RS04780
uniprot id: Q8CME4
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

211586:SO RS11500
gene id: 211586:SO_RS11500
uniprot id: Q8EE85
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the QueC family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).

211586:SO RS20290
gene id: 211586:SO_RS20290
uniprot id: Q8E9B5
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

211586:SO RS06100
gene id: 211586:SO_RS06100
uniprot id: Q8EHB3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 2 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

211586:SO RS05735
gene id: 211586:SO_RS05735
uniprot id: Q8EHI9
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
messages: Binds 1 molybdenum-bis(molybdopterin guanine dinucleotide) (Mo-bis-MGD) cofactor per subunit.
messages: Periplasm
messages: Predicted to be exported by the Tat system. The position of the signal peptide cleavage has not been experimentally proven.
messages: Reduces trimethylamine-N-oxide (TMAO) into trimethylamine; an anaerobic reaction coupled to energy-yielding reactions.

211586:SO RS20235
gene id: 211586:SO_RS20235
uniprot id: Q8E9C7
names: Function
messages: Electron transfer subunit of the terminal reductase during anaerobic growth on various sulfoxide and N-oxide compounds.

211586:SO RS14280
gene id: 211586:SO_RS14280
uniprot id: Q8ECQ5
names: Subcellular Location Annotation
messages: Membrane

211586:SO RS16345
gene id: 211586:SO_RS16345
uniprot id: Q8EBL4
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

211586:SO RS21615
gene id: 211586:SO_RS21615
uniprot id: Q8E8L1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic sulfate-binding protein family.
messages: Periplasm

211586:SO RS16610
gene id: 211586:SO_RS16610
uniprot id: Q8EBG4
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

211586:SO RS00675
gene id: 211586:SO_RS00675
uniprot id: Q8EKF2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DHBP synthase family.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Homodimer.

211586:SO RS10460
gene id: 211586:SO_RS10460
uniprot id: Q8EET6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Bcr/CmlA family.
messages: Cell inner membrane
messages: Membrane

211586:SO RS13375
gene id: 211586:SO_RS13375
uniprot id: Q8ED80
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Homodimer.
messages: Multifunctional regulator of fatty acid metabolism.

211586:SO RS11065
gene id: 211586:SO_RS11065
uniprot id: Q8EEG9
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily. UbiG/COQ3 family.
messages: O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway.

211586:SO RS18835
gene id: 211586:SO_RS18835
uniprot id: Q8EA54
names: Similarity
names: Subunit
messages: Homotetramer.
messages: In the C-terminal section; belongs to the homoserine dehydrogenase family.
messages: In the N-terminal section; belongs to the aspartokinase family.

211586:SO RS18355
gene id: 211586:SO_RS18355
uniprot id: Q8EAF9
names: Similarity
messages: Belongs to the peptidase S1C family.

211586:SO RS14210
gene id: 211586:SO_RS14210
uniprot id: Q8ECR9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell inner membrane
messages: Membrane

211586:SO RS09685
gene id: 211586:SO_RS09685
uniprot id: Q8EF81
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

211586:SO RS15030
gene id: 211586:SO_RS15030
uniprot id: Q8ECC1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliL family.
messages: Cell inner membrane
messages: Controls the rotational direction of flagella during chemotaxis.
messages: Membrane

211586:SO RS13235
gene id: 211586:SO_RS13235
uniprot id: Q8EDA9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

211586:SO RS02850
gene id: 211586:SO_RS02850
uniprot id: Q8EJ72
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm

211586:SO RS18695
gene id: 211586:SO_RS18695
uniprot id: Q8EA86
names: Similarity
messages: Belongs to the peptidase M16 family.

211586:SO RS15640
gene id: 211586:SO_RS15640
uniprot id: Q8EBZ0
names: Similarity
messages: Belongs to the YggT family.

211586:SO RS00490
gene id: 211586:SO_RS00490
uniprot id: Q8EKJ1
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.

211586:SO RS21405
gene id: 211586:SO_RS21405
uniprot id: Q8E8Q3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COX11/CtaG family.
messages: Cell inner membrane
messages: Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I.

211586:SO RS04445
gene id: 211586:SO_RS04445
uniprot id: Q8EI97
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

211586:SO RS06055
gene id: 211586:SO_RS06055
uniprot id: Q8EHC4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HesB/IscA family.
messages: Binds 1 iron-sulfur cluster per subunit.
messages: Homodimer.
messages: Required for insertion of 4Fe-4S clusters for at least IspG.

211586:SO RS15065
gene id: 211586:SO_RS15065
uniprot id: Q8ECB4
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliE family.

211586:SO RS20670
gene id: 211586:SO_RS20670
uniprot id: Q8E939
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

211586:SO RS08765
gene id: 211586:SO_RS08765
uniprot id: Q8EFS1
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

211586:SO RS21925
gene id: 211586:SO_RS21925
uniprot id: Q8E8E8
names: Subcellular Location Annotation
messages: Membrane

211586:SO RS22230
gene id: 211586:SO_RS22230
uniprot id: Q8CME3
names: Similarity
messages: Belongs to the site-specific recombinase resolvase family.

211586:SO RS15130
gene id: 211586:SO_RS15130
uniprot id: Q8ECA2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
messages: Bacterial flagellum basal body
messages: Belongs to the FlgI family.
messages: Periplasm
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod.

211586:SO RS12020
gene id: 211586:SO_RS12020
uniprot id: Q8EDY2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Cytoplasm
messages: Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA.

211586:SO RS04470
gene id: 211586:SO_RS04470
uniprot id: Q7ZAJ8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerD subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

211586:SO RS13180
gene id: 211586:SO_RS13180
uniprot id: Q8EDB5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

211586:SO RS12135
gene id: 211586:SO_RS12135
uniprot id: Q8CX40
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm

211586:SO RS11415
gene id: 211586:SO_RS11415
uniprot id: Q8EE99
names: Function
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.
messages: Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.

211586:SO RS20200
gene id: 211586:SO_RS20200
uniprot id: Q8E9D5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.

211586:SO RS04125
gene id: 211586:SO_RS04125
uniprot id: Q8EIG1
names: Similarity
messages: Belongs to the phosphoribulokinase family.

211586:SO RS11395
gene id: 211586:SO_RS11395
uniprot id: Q8EEA3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 5DNU family.
messages: Catalyzes the strictly specific dephosphorylation of 2'-deoxyribonucleoside 5'-monophosphates.
messages: Cytoplasm
messages: Homodimer.

211586:SO RS10005
gene id: 211586:SO_RS10005
uniprot id: Q8EF25
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YejK family.
messages: nucleoid

211586:SO RS05340
gene id: 211586:SO_RS05340
uniprot id: Q8EHQ9
names: Similarity
messages: Belongs to the Dps family.

211586:SO RS07120
gene id: 211586:SO_RS07120
uniprot id: Q8EGR2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

211586:SO RS12525
gene id: 211586:SO_RS12525
uniprot id: Q8EDN0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nicotinamide ribonucleoside (NR) uptake permease (TC 4.B.1) family.
messages: Membrane
messages: Required for nicotinamide riboside transport across the inner membrane.

211586:SO RS07755
gene id: 211586:SO_RS07755
uniprot id: Q8EGC4
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

211586:SO RS09065
gene id: 211586:SO_RS09065
uniprot id: Q8EFL0
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

211586:SO RS14430
gene id: 211586:SO_RS14430
uniprot id: Q8ECM6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell inner membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

211586:SO RS08500
gene id: 211586:SO_RS08500
uniprot id: Q8EFW5
names: Disruption Phenotype
names: Domain
names: Function
names: Induction
names: Miscellaneous
names: Subunit
messages: Deletion of the gene leads to a dramatically reduced growth at low temperature.
messages: Interacts via its C-terminal extension with AtcC (PubMed:31482142). Does not interact with AtcA and AtcB (PubMed:31482142).
messages: Involved in cold adaptation (PubMed:31482142). The J-domain is functional and can stimulate the ATPase activity of the DnaK chaperone (PubMed:31482142). May work as a co-chaperone of the DnaK system to support cold resistance (PubMed:31482142).
messages: Part of the atcJABC operon (PubMed:31482142). The operon is constitutively expressed, and expression shows only a very slight increase at low temperature (PubMed:31482142).
messages: Stimulation of the ATPase activity of DnaK is much higher with DnaJ than with AtcJ.
messages: The J-domain is required for stimulation of DnaK activity (PubMed:31482142). The C-terminal extension of 21 amino acids is essential for AtcC binding and to support cold resistance (PubMed:31482142).

211586:SO RS08930
gene id: 211586:SO_RS08930
uniprot id: Q8EFN7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

211586:SO RS08400
gene id: 211586:SO_RS08400
uniprot id: Q8EFY8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

211586:SO RS10780
gene id: 211586:SO_RS10780
uniprot id: Q8EEM8
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.

211586:SO RS11050
gene id: 211586:SO_RS11050
uniprot id: Q8EEH2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
messages: Cytoplasm
messages: Homodimer.

211586:SO RS16205
gene id: 211586:SO_RS16205
uniprot id: Q8EBP3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.
messages: Forms an icosahedral capsid composed of 60 subunits, arranged as a dodecamer of pentamers.

211586:SO RS20010
gene id: 211586:SO_RS20010
uniprot id: Q8E9G7
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Involved in a late step of protoheme IX synthesis.
messages: Membrane

211586:SO RS10545
gene id: 211586:SO_RS10545
uniprot id: Q8EER9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr). Also edits incorrectly charged L-seryl-tRNA(Thr).
messages: Cytoplasm
messages: Homodimer.

211586:SO RS07690
gene id: 211586:SO_RS07690
uniprot id: Q8EGD8
names: Similarity
messages: Belongs to the biopterin-dependent aromatic amino acid hydroxylase family.

211586:SO RS18425
gene id: 211586:SO_RS18425
uniprot id: Q8EAE8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptC family.
messages: Cell inner membrane
messages: Component of the lipopolysaccharide transport and assembly complex. Interacts with LptA and the LptBFG transporter complex.
messages: Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. Facilitates the transfer of LPS from the inner membrane to the periplasmic protein LptA. Could be a docking site for LptA.
messages: Required for the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane.

211586:SO RS06245
gene id: 211586:SO_RS06245
uniprot id: Q8EH83
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell inner membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

211586:SO RS14390
gene id: 211586:SO_RS14390
uniprot id: Q8ECN4
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

211586:SO RS16190
gene id: 211586:SO_RS16190
uniprot id: Q8EBP6
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG).

211586:SO RS12025
gene id: 211586:SO_RS12025
uniprot id: Q8EDY1
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. TatD-type hydrolase family.

211586:SO RS16515
gene id: 211586:SO_RS16515
uniprot id: Q8EBI3
names: Function
names: Similarity
messages: Belongs to the ribF family.
messages: Catalyzes the phosphorylation of riboflavin to FMN followed by the adenylation of FMN to FAD.

211586:SO RS18865
gene id: 211586:SO_RS18865
uniprot id: Q8EA47
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.

211586:SO RS08115
gene id: 211586:SO_RS08115
uniprot id: Q8EG40
names: Similarity
messages: Belongs to the glycerate kinase type-1 family.

211586:SO RS15825
gene id: 211586:SO_RS15825
uniprot id: Q8EBV4
names: Similarity
messages: Belongs to the peptidase S16 family.

211586:SO RS01820
gene id: 211586:SO_RS01820
uniprot id: Q8EJT2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HsdR family.
messages: Subunit R is required for both nuclease and ATPase activities, but not for modification.
messages: The type I restriction/modification system is composed of three polypeptides R, M and S.

211586:SO RS17780
gene id: 211586:SO_RS17780
uniprot id: Q8EAS3
names: Similarity
messages: Belongs to the P(II) protein family.

211586:SO RS14360
gene id: 211586:SO_RS14360
uniprot id: Q8ECN9
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

211586:SO RS18545
gene id: 211586:SO_RS18545
uniprot id: Q8EAC1
names: Similarity
messages: Belongs to the aspartokinase family.

211586:SO RS01150
gene id: 211586:SO_RS01150
uniprot id: Q8EK59
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

211586:SO RS19870
gene id: 211586:SO_RS19870
uniprot id: Q8E9J1
names: Similarity
messages: Belongs to the MotB family.

211586:SO RS07080
gene id: 211586:SO_RS07080
uniprot id: Q8EGS0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

211586:SO RS01075
gene id: 211586:SO_RS01075
uniprot id: P59166
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

211586:SO RS14800
gene id: 211586:SO_RS14800
uniprot id: Q8ECG7
names: Similarity
messages: Belongs to the asparagine synthetase family.

211586:SO RS11555
gene id: 211586:SO_RS11555
uniprot id: Q8EE79
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfC subfamily.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell inner membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

211586:SO RS03320
gene id: 211586:SO_RS03320
uniprot id: Q8EIX6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

211586:SO RS04080
gene id: 211586:SO_RS04080
uniprot id: Q8EIH0
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

211586:SO RS03645
gene id: 211586:SO_RS03645
uniprot id: Q8EIR3
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

211586:SO RS05465
gene id: 211586:SO_RS05465
uniprot id: Q8EHN6
names: Similarity
messages: Belongs to the UbiH/COQ6 family.

211586:SO RS18700
gene id: 211586:SO_RS18700
uniprot id: Q8CMJ3
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

211586:SO RS22845
gene id: 211586:SO_RS22845
uniprot id: Q8E807
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

211586:SO RS01670
gene id: 211586:SO_RS01670
uniprot id: Q8EJV7
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

211586:SO RS05195
gene id: 211586:SO_RS05195
uniprot id: Q8EHT9
names: Similarity
messages: Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily.

211586:SO RS16835
gene id: 211586:SO_RS16835
uniprot id: Q8EBC4
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Membrane
messages: Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (CysA), two transmembrane proteins (CysT and CysW) and a solute-binding protein (CysP).

211586:SO RS04325
gene id: 211586:SO_RS04325
uniprot id: Q8EIC1
names: Subcellular Location Annotation
messages: Membrane

211586:SO RS11200
gene id: 211586:SO_RS11200
uniprot id: Q8EEE1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ThiG family.
messages: Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
messages: Cytoplasm
messages: Homotetramer. Forms heterodimers with either ThiH or ThiS.

211586:SO RS16445
gene id: 211586:SO_RS16445
uniprot id: Q8EBJ6
names: Similarity
messages: Belongs to the P(II) protein family.

211586:SO RS20050
gene id: 211586:SO_RS20050
uniprot id: Q8E9G3
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

211586:SO RS02840
gene id: 211586:SO_RS02840
uniprot id: Q8CMJ3
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

211586:SO RS09700
gene id: 211586:SO_RS09700
uniprot id: Q8EF77
names: Similarity
messages: Belongs to the YkuD family.

211586:SO RS05065
gene id: 211586:SO_RS05065
uniprot id: Q8CX47
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

211586:SO RS09770
gene id: 211586:SO_RS09770
uniprot id: Q8EF64
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

211586:SO RS09285
gene id: 211586:SO_RS09285
uniprot id: Q8EFF9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

211586:SO RS10430
gene id: 211586:SO_RS10430
uniprot id: Q8CMJ3
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

211586:SO RS06400
gene id: 211586:SO_RS06400
uniprot id: Q8EH53
names: Similarity
messages: Belongs to the band 7/mec-2 family. Flotillin subfamily.

211586:SO RS00770
gene id: 211586:SO_RS00770
uniprot id: Q8EKC8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: ATPase component of the type II secretion system required for the energy-dependent secretion of extracellular factors such as proteases and toxins from the periplasm. Acts as a molecular motor to provide the energy that is required for assembly of the pseudopilus and the extrusion of substrates generated in the cytoplasm.
messages: Belongs to the GSP E family.
messages: Cell inner membrane

211586:SO RS12625
gene id: 211586:SO_RS12625
uniprot id: Q8EDK9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dethiobiotin synthetase family.
messages: Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

211586:SO RS19280
gene id: 211586:SO_RS19280
uniprot id: Q8E9U9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
messages: Belongs to the ClpX chaperone family. HslU subfamily.
messages: Cytoplasm

211586:SO RS19725
gene id: 211586:SO_RS19725
uniprot id: Q8E9L6
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family.
messages: Toroid-shaped homodecamer, composed of two pentamers of five dimers.

211586:SO RS08815
gene id: 211586:SO_RS08815
uniprot id: Q8EFR2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

211586:SO RS17125
gene id: 211586:SO_RS17125
uniprot id: Q8EB62
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

211586:SO RS06945
gene id: 211586:SO_RS06945
uniprot id: Q8EGU5
names: Function
names: Similarity
messages: Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis.
messages: Belongs to the glycogen phosphorylase family.
messages: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.

211586:SO RS10290
gene id: 211586:SO_RS10290
uniprot id: Q8EEX1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

211586:SO RS21355
gene id: 211586:SO_RS21355
uniprot id: Q8E8R4
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

211586:SO RS15915
gene id: 211586:SO_RS15915
uniprot id: Q8EBT6
names: Similarity
messages: Belongs to the threonine synthase family.

211586:SO RS08820
gene id: 211586:SO_RS08820
uniprot id: Q8EFR0
names: Similarity
messages: Belongs to the DODA-type extradiol aromatic ring-opening dioxygenase family.

211586:SO RS18725
gene id: 211586:SO_RS18725
uniprot id: Q8EA79
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

211586:SO RS09785
gene id: 211586:SO_RS09785
uniprot id: Q8EF61
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CheB family.
messages: Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.
messages: Cytoplasm
messages: Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
messages: Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity.

211586:SO RS09855
gene id: 211586:SO_RS09855
uniprot id: Q8EF50
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAE transporter (TC 2.A.81) family.
messages: Cell membrane

211586:SO RS18360
gene id: 211586:SO_RS18360
uniprot id: Q8CMJ3
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

211586:SO RS01920
gene id: 211586:SO_RS01920
uniprot id: Q8EJR3
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.

211586:SO RS01445
gene id: 211586:SO_RS01445
uniprot id: Q8EK07
names: Similarity
messages: Belongs to the UPF0102 family.

211586:SO RS02555
gene id: 211586:SO_RS02555
uniprot id: Q8EJC9
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

211586:SO RS14175
gene id: 211586:SO_RS14175
uniprot id: Q8ECS6
names: Subcellular Location Annotation
messages: Periplasm

211586:SO RS05260
gene id: 211586:SO_RS05260
uniprot id: Q8EHS6
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

211586:SO RS05105
gene id: 211586:SO_RS05105
uniprot id: Q8EHV9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NqrA family.
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

211586:SO RS14825
gene id: 211586:SO_RS14825
uniprot id: K4PW15
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

211586:SO RS16915
gene id: 211586:SO_RS16915
uniprot id: Q8EBA7
names: Subcellular Location Annotation
messages: Periplasm

211586:SO RS00200
gene id: 211586:SO_RS00200
uniprot id: Q8EKQ0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the shikimate dehydrogenase family.
messages: Homodimer.
messages: Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).

211586:SO RS05750
gene id: 211586:SO_RS05750
uniprot id: Q8EHI5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Membrane

211586:SO RS19535
gene id: 211586:SO_RS19535
uniprot id: Q8E9Q2
names: Function
names: Similarity
messages: Belongs to the LpxC family.
messages: Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.

211586:SO RS05610
gene id: 211586:SO_RS05610
uniprot id: Q8EHL5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

211586:SO RS16510
gene id: 211586:SO_RS16510
uniprot id: Q8EBI4
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

211586:SO RS06000
gene id: 211586:SO_RS06000
uniprot id: Q8EHD3
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell inner membrane

211586:SO RS11840
gene id: 211586:SO_RS11840
uniprot id: Q8EE19
names: Similarity
messages: Belongs to the DEAD box helicase family.

211586:SO RS20345
gene id: 211586:SO_RS20345
uniprot id: Q8E9A4
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

211586:SO RS02705
gene id: 211586:SO_RS02705
uniprot id: Q8EJA0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RraB family.
messages: Cytoplasm
messages: Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome.
messages: Interacts with the C-terminal region of Rne.

211586:SO RS00120
gene id: 211586:SO_RS00120
uniprot id: Q8EKR6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TrkH potassium transport family.
messages: Cell inner membrane
messages: Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA.
messages: Membrane

211586:SO RS09280
gene id: 211586:SO_RS09280
uniprot id: Q8EFG0
names: Similarity
messages: Belongs to the DnaX/STICHEL family.

211586:SO RS17615
gene id: 211586:SO_RS17615
uniprot id: Q8EAW1
names: Subcellular Location Annotation
messages: Membrane

211586:SO RS06860
gene id: 211586:SO_RS06860
uniprot id: Q8EGW6
names: Similarity
messages: Belongs to the UPF0125 (RnfH) family.

211586:SO RS10355
gene id: 211586:SO_RS10355
uniprot id: Q8EEV6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

211586:SO RS10015
gene id: 211586:SO_RS10015
uniprot id: Q8EF23
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.

211586:SO RS13560
gene id: 211586:SO_RS13560
uniprot id: Q8ED46
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Membrane

211586:SO RS09410
gene id: 211586:SO_RS09410
uniprot id: Q8EFD8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MsrQ family.
messages: Binds 1 FMN per subunit.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.
messages: Cell inner membrane
messages: Heterodimer of a catalytic subunit (MsrP) and a heme-binding subunit (MsrQ).
messages: Membrane
messages: Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain.

211586:SO RS20180
gene id: 211586:SO_RS20180
uniprot id: Q8E9E0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the serine/threonine dehydratase family.
messages: Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.
messages: Homotetramer.

211586:SO RS19790
gene id: 211586:SO_RS19790
uniprot id: Q8E9K4
names: Similarity
messages: Belongs to the HsdR family.

211586:SO RS18345
gene id: 211586:SO_RS18345
uniprot id: Q8EAG1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AFG1 ATPase family. ZapE subfamily.
messages: Cytoplasm
messages: Interacts with FtsZ.
messages: Reduces the stability of FtsZ polymers in the presence of ATP.

211586:SO RS18855
gene id: 211586:SO_RS18855
uniprot id: Q8EA49
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NrfD family.
messages: Membrane

211586:SO RS18230
gene id: 211586:SO_RS18230
uniprot id: Q8EAI6
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

211586:SO RS09595
gene id: 211586:SO_RS09595
uniprot id: Q8EF98
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial histone-like protein family.
messages: Heterodimer of an alpha and a beta chain.
messages: This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.

211586:SO RS09270
gene id: 211586:SO_RS09270
uniprot id: Q8EFG2
names: Subcellular Location Annotation
messages: Cell inner membrane

211586:SO RS09305
gene id: 211586:SO_RS09305
uniprot id: Q8EFF5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Monomer.

211586:SO RS09465
gene id: 211586:SO_RS09465
uniprot id: Q8EFC6
names: Function
names: Similarity
messages: Belongs to the esterase D family.
messages: Serine hydrolase involved in the detoxification of formaldehyde.

211586:SO RS05635
gene id: 211586:SO_RS05635
uniprot id: Q8EHL1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Component of the RNA degradosome, which is a multiprotein complex involved in RNA processing and mRNA degradation.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

211586:SO RS16155
gene id: 211586:SO_RS16155
uniprot id: Q8EBQ3
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. RlmD subfamily.
messages: Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA.

211586:SO RS10600
gene id: 211586:SO_RS10600
uniprot id: Q8EEQ9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.

211586:SO RS15475
gene id: 211586:SO_RS15475
uniprot id: Q8EC26
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

211586:SO RS15605
gene id: 211586:SO_RS15605
uniprot id: Q8EBZ8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF nuclease family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

211586:SO RS16035
gene id: 211586:SO_RS16035
uniprot id: Q8EBR9
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.
messages: This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.

211586:SO RS11145
gene id: 211586:SO_RS11145
uniprot id: Q8EEF1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvC family.
messages: Binds 2 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer which binds Holliday junction (HJ) DNA. The HJ becomes 2-fold symmetrical on binding to RuvC with unstacked arms; it has a different conformation from HJ DNA in complex with RuvA. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair. Endonuclease that resolves HJ intermediates. Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction. The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'. Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange. HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

211586:SO RS15365
gene id: 211586:SO_RS15365
uniprot id: Q8EC51
names: Activity Regulation
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

211586:SO RS05175
gene id: 211586:SO_RS05175
uniprot id: Q8EHU3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Cell membrane
messages: Membrane

211586:SO RS13435
gene id: 211586:SO_RS13435
uniprot id: Q7ZAJ7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.

211586:SO RS04150
gene id: 211586:SO_RS04150
uniprot id: Q8EIF6
names: Similarity
messages: Belongs to the Gfa family.

211586:SO RS00045
gene id: 211586:SO_RS00045
uniprot id: Q8EKT1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

211586:SO RS21815
gene id: 211586:SO_RS21815
uniprot id: Q8E8H1
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

211586:SO RS21725
gene id: 211586:SO_RS21725
uniprot id: Q8E8J0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA.
messages: Homodimer.

211586:SO RS13055
gene id: 211586:SO_RS13055
uniprot id: Q8CMJ3
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

211586:SO RS21855
gene id: 211586:SO_RS21855
uniprot id: Q8E8G2
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

211586:SO RS11870
gene id: 211586:SO_RS11870
uniprot id: Q8EE12
names: Function
names: Similarity
messages: Belongs to the MinE family.
messages: Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.

211586:SO RS05085
gene id: 211586:SO_RS05085
uniprot id: Q8EHW3
names: Similarity
messages: Belongs to the BolA/IbaG family.

211586:SO RS21340
gene id: 211586:SO_RS21340
uniprot id: Q8E8R8
names: Similarity
messages: Belongs to the UPF0319 family.

211586:SO RS16220
gene id: 211586:SO_RS16220
uniprot id: Q8EBP0
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion.
messages: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.
messages: In the C-terminal section; belongs to the HTP reductase family.
messages: In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family.

211586:SO RS11280
gene id: 211586:SO_RS11280
uniprot id: Q8EEC5
names: Similarity
messages: Belongs to the YciI family.

211586:SO RS12200
gene id: 211586:SO_RS12200
uniprot id: Q8EDU6
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

211586:SO RS04675
gene id: 211586:SO_RS04675
uniprot id: Q8EI49
names: Subcellular Location Annotation
messages: Membrane

211586:SO RS03680
gene id: 211586:SO_RS03680
uniprot id: Q8EIQ7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

211586:SO RS06230
gene id: 211586:SO_RS06230
uniprot id: Q8EH86
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E.
messages: Belongs to the RseA family.
messages: Cell inner membrane
messages: Interacts 1:1 with ECF RNA polymerase sigma-E (RpoE); this inhibits the interaction of sigma-E with the RNA polymerase catalytic core and leads to a decreased expression of sigma-E-regulated genes. Interacts with RseB.

211586:SO RS09825
gene id: 211586:SO_RS09825
uniprot id: Q8EF55
names: Similarity
messages: In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.
messages: In the N-terminal section; belongs to the aldehyde dehydrogenase family.

211586:SO RS06990
gene id: 211586:SO_RS06990
uniprot id: Q8EGT5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family. MepA subfamily.
messages: Cell membrane

211586:SO RS16375
gene id: 211586:SO_RS16375
uniprot id: Q8EBL0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. FHS transporter (TC 2.A.1.7) family.
messages: Cell inner membrane
messages: Intake of glucose and galactose.
messages: Membrane

211586:SO RS09435
gene id: 211586:SO_RS09435
uniprot id: Q8EFD3
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

211586:SO RS05840
gene id: 211586:SO_RS05840
uniprot id: Q8EHG3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

211586:SO RS15400
gene id: 211586:SO_RS15400
uniprot id: Q8EC43
names: Similarity
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.

211586:SO RS16135
gene id: 211586:SO_RS16135
uniprot id: Q8CMJ3
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

211586:SO RS17400
gene id: 211586:SO_RS17400
uniprot id: Q8EB01
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAPS reductase family. CysH subfamily.
messages: Catalyzes the formation of sulfite from phosphoadenosine 5'-phosphosulfate (PAPS) using thioredoxin as an electron donor.
messages: Cytoplasm

211586:SO RS06965
gene id: 211586:SO_RS06965
uniprot id: Q8EGU0
names: Similarity
messages: Belongs to the DEAD box helicase family.

211586:SO RS19985
gene id: 211586:SO_RS19985
uniprot id: Q8E9H2
names: Function
names: Similarity
messages: Belongs to the frataxin family.
messages: Involved in iron-sulfur (Fe-S) cluster assembly. May act as a regulator of Fe-S biogenesis.

211586:SO RS09585
gene id: 211586:SO_RS09585
uniprot id: Q8EFA0
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

211586:SO RS18020
gene id: 211586:SO_RS18020
uniprot id: Q8EAM7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family.
messages: Periplasm

211586:SO RS01055
gene id: 211586:SO_RS01055
uniprot id: Q8EK76
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

211586:SO RS09880
gene id: 211586:SO_RS09880
uniprot id: Q8EF45
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit contributes ATPase, 3'-5' helicase, exonuclease activity and loads RecA onto ssDNA.
messages: Belongs to the helicase family. UvrD subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotrimer of RecB, RecC and RecD. All subunits contribute to DNA-binding. Interacts with RecA.
messages: The C-terminal domain has nuclease activity and interacts with RecD. It interacts with RecA, facilitating its loading onto ssDNA.
messages: The N-terminal DNA-binding domain is a ssDNA-dependent ATPase and has ATP-dependent 3'-5' helicase function. This domain interacts with RecC.

211586:SO RS05365
gene id: 211586:SO_RS05365
uniprot id: Q8EHQ4
names: Similarity
messages: Belongs to the UPF0250 family.

211586:SO RS14625
gene id: 211586:SO_RS14625
uniprot id: K4PU34
names: Similarity
messages: In the C-terminal section; belongs to the transpeptidase family.
messages: In the N-terminal section; belongs to the glycosyltransferase 51 family.

211586:SO RS07710
gene id: 211586:SO_RS07710
uniprot id: Q8EGD3
names: Similarity
messages: Belongs to the GST superfamily. Zeta family.

211586:SO RS09530
gene id: 211586:SO_RS09530
uniprot id: Q8EFB1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.

211586:SO RS01095
gene id: 211586:SO_RS01095
uniprot id: Q8EK69
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

211586:SO RS05805
gene id: 211586:SO_RS05805
uniprot id: Q8EHH2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase U32 family. UbiU subfamily.
messages: Forms an heterodimer with UbiV.
messages: Required for O(2)-independent ubiquinone (coenzyme Q) biosynthesis. Together with UbiV, is essential for the C6-hydroxylation reaction in the oxygen-independent ubiquinone biosynthesis pathway.

211586:SO RS07225
gene id: 211586:SO_RS07225
uniprot id: Q8EGP0
names: Function
messages: Member of the two-component regulatory system PhoR/PhoB involved in the phosphate regulon genes expression. PhoR may function as a membrane-associated protein kinase that phosphorylates PhoB in response to environmental signals.

211586:SO RS01170
gene id: 211586:SO_RS01170
uniprot id: Q8EK55
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

211586:SO RS10735
gene id: 211586:SO_RS10735
uniprot id: Q8EEN6
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

211586:SO RS00020
gene id: 211586:SO_RS00020
uniprot id: Q8EKT6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Cell inner membrane
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

211586:SO RS05330
gene id: 211586:SO_RS05330
uniprot id: Q8EHR1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

211586:SO RS07105
gene id: 211586:SO_RS07105
uniprot id: Q8EGR5
names: Similarity
messages: Belongs to the MotB family.

211586:SO RS05810
gene id: 211586:SO_RS05810
uniprot id: Q8EHH1
names: Function
names: Similarity
messages: Belongs to the UbiT family.
messages: Required for O(2)-independent ubiquinone (coenzyme Q) biosynthesis. Likely functions as an accessory factor.

211586:SO RS10570
gene id: 211586:SO_RS10570
uniprot id: K4PU16
names: Similarity
messages: Belongs to the AlaDH/PNT family.

211586:SO RS18960
gene id: 211586:SO_RS18960
uniprot id: Q8EA19
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

211586:SO RS04390
gene id: 211586:SO_RS04390
uniprot id: Q8EIA8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NhaD Na(+)/H(+) (TC 2.A.62) antiporter family.
messages: Membrane

211586:SO RS11860
gene id: 211586:SO_RS11860
uniprot id: Q8EE14
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MinC family.
messages: Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization.
messages: Interacts with MinD and FtsZ.

211586:SO RS18240
gene id: 211586:SO_RS18240
uniprot id: Q8EAI4
names: Similarity
messages: Belongs to the peptidase S46 family.

211586:SO RS14695
gene id: 211586:SO_RS14695
uniprot id: Q8ECI8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.
messages: Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.
messages: Cytoplasm
messages: Homodimer.

211586:SO RS00040
gene id: 211586:SO_RS00040
uniprot id: Q8EKT2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

211586:SO RS01215
gene id: 211586:SO_RS01215
uniprot id: P59375
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

211586:SO RS21655
gene id: 211586:SO_RS21655
uniprot id: Q8E8K6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmJ family.
messages: Cytoplasm
messages: Specifically methylates the guanosine in position 1516 of 16S rRNA.

211586:SO RS17030
gene id: 211586:SO_RS17030
uniprot id: Q8EB84
names: Similarity
messages: Belongs to the ThrE exporter (TC 2.A.79) family.

211586:SO RS02880
gene id: 211586:SO_RS02880
uniprot id: Q8EJ67
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the band 7/mec-2 family. HflK subfamily.
messages: HflC and HflK could encode or regulate a protease.
messages: HflC and HflK may interact to form a multimeric complex.
messages: Membrane

211586:SO RS14410
gene id: 211586:SO_RS14410
uniprot id: Q8ECN0
names: Similarity
messages: Belongs to the peptidase S8 family.

211586:SO RS18740
gene id: 211586:SO_RS18740
uniprot id: Q8EA75
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DEAD box helicase family. DeaD/CsdA subfamily.
messages: Cytoplasm
messages: DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation.

211586:SO RS18085
gene id: 211586:SO_RS18085
uniprot id: Q8EAL7
names: Similarity
messages: Belongs to the AAA ATPase family.

211586:SO RS05660
gene id: 211586:SO_RS05660
uniprot id: Q8EHK6
names: Similarity
messages: Belongs to the nucleoside-specific channel-forming outer membrane porin (Tsx) (TC 1.B.10) family.

211586:SO RS02345
gene id: 211586:SO_RS02345
uniprot id: Q8EJH4
names: Similarity
messages: Belongs to the peptidase M13 family.

211586:SO RS20635
gene id: 211586:SO_RS20635
uniprot id: Q8E946
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane.

211586:SO RS15440
gene id: 211586:SO_RS15440
uniprot id: Q8EC33
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

211586:SO RS16055
gene id: 211586:SO_RS16055
uniprot id: Q8EBR5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SurE nucleotidase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Cytoplasm
messages: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.

211586:SO RS02095
gene id: 211586:SO_RS02095
uniprot id: Q8EJM8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the uroporphyrinogen decarboxylase family.
messages: Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
messages: Cytoplasm
messages: Homodimer.

211586:SO RS05470
gene id: 211586:SO_RS05470
uniprot id: Q8EHN5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

211586:SO RS07680
gene id: 211586:SO_RS07680
uniprot id: Q8EGE0
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

211586:SO RS04370
gene id: 211586:SO_RS04370
uniprot id: Q8EIB2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. Epd subfamily.
messages: Catalyzes the NAD-dependent conversion of D-erythrose 4-phosphate to 4-phosphoerythronate.
messages: Cytoplasm
messages: Homotetramer.

211586:SO RS05625
gene id: 211586:SO_RS05625
uniprot id: Q8EHL3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

211586:SO RS07940
gene id: 211586:SO_RS07940
uniprot id: Q8EG81
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

211586:SO RS16685
gene id: 211586:SO_RS16685
uniprot id: Q8EBF2
names: Similarity
messages: Belongs to the UPF0319 family.

211586:SO RS21800
gene id: 211586:SO_RS21800
uniprot id: Q8E8H4
names: Subcellular Location Annotation
messages: Membrane

211586:SO RS10330
gene id: 211586:SO_RS10330
uniprot id: P59273
names: Similarity
messages: Belongs to the UPF0227 family.

211586:SO RS16455
gene id: 211586:SO_RS16455
uniprot id: Q8EBJ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP H family.
messages: Cell inner membrane
messages: Membrane

211586:SO RS19605
gene id: 211586:SO_RS19605
uniprot id: Q8E9N9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MraZ family.
messages: Forms oligomers.
messages: nucleoid

211586:SO RS16030
gene id: 211586:SO_RS16030
uniprot id: Q8EBS0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

211586:SO RS12910
gene id: 211586:SO_RS12910
uniprot id: Q8EDG5
names: Subcellular Location Annotation
messages: Cytoplasm

211586:SO RS03845
gene id: 211586:SO_RS03845
uniprot id: Q8EIM1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LysR transcriptional regulatory family.
messages: Cytoplasm

211586:SO RS10380
gene id: 211586:SO_RS10380
uniprot id: Q8EEV1
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

211586:SO RS05255
gene id: 211586:SO_RS05255
uniprot id: Q8EHS7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

211586:SO RS21220
gene id: 211586:SO_RS21220
uniprot id: Q8E8T8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NrfD family.
messages: Membrane

211586:SO RS00915
gene id: 211586:SO_RS00915
uniprot id: Q8EK98
names: Subcellular Location Annotation
messages: Membrane

211586:SO RS06075
gene id: 211586:SO_RS06075
uniprot id: Q8EHB9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

211586:SO RS18970
gene id: 211586:SO_RS18970
uniprot id: Q8EA17
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.

211586:SO RS08555
gene id: 211586:SO_RS08555
uniprot id: Q8EFV8
names: Similarity
messages: Belongs to the peptidase S16 family.

211586:SO RS20500
gene id: 211586:SO_RS20500
uniprot id: Q8E969
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DcuA/DcuB transporter (TC 2.A.13.1) family.
messages: Cell inner membrane
messages: Membrane
messages: Responsible for the transport of C4-dicarboxylates.

211586:SO RS05895
gene id: 211586:SO_RS05895
uniprot id: Q8EHF2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family.
messages: Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system.
messages: The complex is composed of two ATP-binding proteins (PotA), two transmembrane proteins (PotB and PotC) and a solute-binding protein (PotD).

211586:SO RS10190
gene id: 211586:SO_RS10190
uniprot id: Q8EEZ2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

211586:SO RS20095
gene id: 211586:SO_RS20095
uniprot id: Q8E9F8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. UvrD subfamily.
messages: Homodimer.
messages: Rep helicase is a single-stranded DNA-dependent ATPase involved in DNA replication; it can initiate unwinding at a nick in the DNA. It binds to the single-stranded DNA and acts in a progressive fashion along the DNA in the 3' to 5' direction.

211586:SO RS03560
gene id: 211586:SO_RS03560
uniprot id: Q8EIS9
names: Function
names: Similarity
messages: Belongs to the class-I DAHP synthase family.
messages: Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP).

211586:SO RS12985
gene id: 211586:SO_RS12985
uniprot id: Q8EDF0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. Lipid exporter (TC 3.A.1.106) family.
messages: Cell inner membrane
messages: Homodimer.
messages: In MsbA the ATP-binding domain (NBD) and the transmembrane domain (TMD) are fused.
messages: Involved in lipopolysaccharide (LPS) biosynthesis. Translocates lipid A-core from the inner to the outer leaflet of the inner membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation.

211586:SO RS02655
gene id: 211586:SO_RS02655
uniprot id: Q8EJA9
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. CmoM family.
messages: Catalyzes the methylation of 5-carboxymethoxyuridine (cmo5U) to form 5-methoxycarbonylmethoxyuridine (mcmo5U) at position 34 in tRNAs.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

211586:SO RS04730
gene id: 211586:SO_RS04730
uniprot id: Q8EI37
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 6 family.
messages: Cell membrane
messages: Composed of 13 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

211586:SO RS05800
gene id: 211586:SO_RS05800
uniprot id: Q8EHH3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase U32 family. UbiV subfamily.
messages: Forms an heterodimer with UbiU.
messages: Required for O(2)-independent ubiquinone (coenzyme Q) biosynthesis. Together with UbiU, is essential for the C6-hydroxylation reaction in the oxygen-independent ubiquinone biosynthesis pathway.

211586:SO RS00910
gene id: 211586:SO_RS00910
uniprot id: Q8EK99
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the selenophosphate synthase 1 family. Class I subfamily.
messages: Binds 1 Mg(2+) ion per monomer.
messages: Homodimer.
messages: Synthesizes selenophosphate from selenide and ATP.

211586:SO RS05250
gene id: 211586:SO_RS05250
uniprot id: Q8EHS8
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

211586:SO RS20360
gene id: 211586:SO_RS20360
uniprot id: Q8E9A1
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

211586:SO RS01110
gene id: 211586:SO_RS01110
uniprot id: Q8EK66
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

211586:SO RS01590
gene id: 211586:SO_RS01590
uniprot id: Q8EJX3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbA subfamily.
messages: Periplasm

211586:SO RS01000
gene id: 211586:SO_RS01000
uniprot id: Q8EK84
names: Function
names: Similarity
messages: Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon.
messages: Belongs to the biotin--protein ligase family.

211586:SO RS19635
gene id: 211586:SO_RS19635
uniprot id: Q8E9N4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

211586:SO RS11075
gene id: 211586:SO_RS11075
uniprot id: Q8EEG7
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

211586:SO RS19250
gene id: 211586:SO_RS19250
uniprot id: Q8E9V8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

211586:SO RS12505
gene id: 211586:SO_RS12505
uniprot id: Q8EDN5
names: Cofactor
names: Similarity
messages: Belongs to the nitroreductase family.
messages: Binds 1 FMN per subunit.

211586:SO RS08755
gene id: 211586:SO_RS08755
uniprot id: Q8EFS3
names: Similarity
messages: Belongs to the HMG-CoA lyase family.

211586:SO RS18850
gene id: 211586:SO_RS18850
uniprot id: Q8EA51
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

211586:SO RS11935
gene id: 211586:SO_RS11935
uniprot id: Q8EDZ9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ZapC family.
messages: Contributes to the efficiency of the cell division process by stabilizing the polymeric form of the cell division protein FtsZ. Acts by promoting interactions between FtsZ protofilaments and suppressing the GTPase activity of FtsZ.
messages: Cytoplasm
messages: Interacts directly with FtsZ.

211586:SO RS03950
gene id: 211586:SO_RS03950
uniprot id: Q8EIJ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

211586:SO RS22515
gene id: 211586:SO_RS22515
uniprot id: Q8CMJ3
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

211586:SO RS17220
gene id: 211586:SO_RS17220
uniprot id: K4PSV9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

211586:SO RS04875
gene id: 211586:SO_RS04875
uniprot id: Q8EI06
names: Subcellular Location Annotation
messages: Membrane

211586:SO RS08640
gene id: 211586:SO_RS08640
uniprot id: Q8EFU5
names: Function
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. SpeA subfamily.
messages: Catalyzes the biosynthesis of agmatine from arginine.

211586:SO RS01345
gene id: 211586:SO_RS01345
uniprot id: Q8EK27
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm

211586:SO RS14985
gene id: 211586:SO_RS14985
uniprot id: Q8ECD1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTP-binding SRP family.
messages: Cell membrane
messages: Membrane
messages: Necessary for flagellar biosynthesis. May be involved in translocation of the flagellum.

211586:SO RS00805
gene id: 211586:SO_RS00805
uniprot id: Q8EKC1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP L family.
messages: Cell inner membrane
messages: Inner membrane component of the type II secretion system required for the energy-dependent secretion of extracellular factors such as proteases and toxins from the periplasm.
messages: Membrane

211586:SO RS16505
gene id: 211586:SO_RS16505
uniprot id: Q8EBI5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell inner membrane
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

211586:SO RS20460
gene id: 211586:SO_RS20460
uniprot id: Q8E981
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the peroxidase family. Peroxidase/catalase subfamily.
messages: Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per dimer.
messages: Formation of the three residue Trp-Tyr-Met cross-link is important for the catalase, but not the peroxidase activity of the enzyme.
messages: Homodimer or homotetramer.

211586:SO RS17990
gene id: 211586:SO_RS17990
uniprot id: Q8EAN4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane.

211586:SO RS06590
gene id: 211586:SO_RS06590
uniprot id: Q8EH13
names: Cofactor
names: Similarity
messages: Belongs to the ApbE family.
messages: Magnesium. Can also use manganese.

211586:SO RS06855
gene id: 211586:SO_RS06855
uniprot id: Q8EGW7
names: Similarity
messages: Belongs to the ribosome association toxin RatA family.

211586:SO RS17165
gene id: 211586:SO_RS17165
uniprot id: Q8EB54
names: Similarity
messages: Belongs to the universal stress protein A family.

211586:SO RS01770
gene id: 211586:SO_RS01770
uniprot id: Q8EJT8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

211586:SO RS13135
gene id: 211586:SO_RS13135
uniprot id: Q8EDC6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

211586:SO RS19045
gene id: 211586:SO_RS19045
uniprot id: Q8EA01
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Membrane

211586:SO RS09140
gene id: 211586:SO_RS09140
uniprot id: Q8EFJ5
names: Subcellular Location Annotation
messages: Cell inner membrane

211586:SO RS03915
gene id: 211586:SO_RS03915
uniprot id: Q8EIK6
names: Similarity
messages: Belongs to the EndA/NucM nuclease family.

211586:SO RS08795
gene id: 211586:SO_RS08795
uniprot id: Q8EFR6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

211586:SO RS05740
gene id: 211586:SO_RS05740
uniprot id: Q8EHI8
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TorC/TorY family.
messages: Binds 5 heme groups per subunit.
messages: Cell inner membrane
messages: Membrane

211586:SO RS07505
gene id: 211586:SO_RS07505
uniprot id: Q8EGH9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family.
messages: Cytoplasm
messages: Homotrimer.

211586:SO RS19550
gene id: 211586:SO_RS19550
uniprot id: Q8E9P9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsQ/DivIB family. FtsQ subfamily.
messages: Cell inner membrane
messages: Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly.
messages: Part of a complex composed of FtsB, FtsL and FtsQ.

211586:SO RS08295
gene id: 211586:SO_RS08295
uniprot id: Q8EG09
names: Similarity
messages: Belongs to the bacterial solute-binding protein 5 family.

211586:SO RS08690
gene id: 211586:SO_RS08690
uniprot id: Q8EFT6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamC family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

211586:SO RS18135
gene id: 211586:SO_RS18135
uniprot id: Q8EAK6
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

211586:SO RS05115
gene id: 211586:SO_RS05115
uniprot id: Q8EHV7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrC family.
messages: Cell inner membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

211586:SO RS00410
gene id: 211586:SO_RS00410
uniprot id: Q8EKL1
names: Similarity
messages: Belongs to the Gfa family.

211586:SO RS14660
gene id: 211586:SO_RS14660
uniprot id: Q8ECJ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone-like protein H-NS family.
messages: nucleoid

211586:SO RS01280
gene id: 211586:SO_RS01280
uniprot id: Q8EK36
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbE subfamily.
messages: Cell inner membrane

211586:SO RS15695
gene id: 211586:SO_RS15695
uniprot id: Q8EBX8
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.

211586:SO RS17575
gene id: 211586:SO_RS17575
uniprot id: Q8EAX0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
messages: Membrane

211586:SO RS00800
gene id: 211586:SO_RS00800
uniprot id: Q8EKC2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP K family.
messages: Cell inner membrane
messages: Membrane

211586:SO RS06250
gene id: 211586:SO_RS06250
uniprot id: Q8EH82
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

211586:SO RS01440
gene id: 211586:SO_RS01440
uniprot id: Q8EK08
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SIS family. GmhA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate.
messages: Cytoplasm
messages: Homotetramer.
messages: The reaction produces a racemic mixture of D-glycero-alpha-D-manno-heptose 7-phosphate and D-glycero-beta-D-manno-heptose 7-phosphate.

211586:SO RS19110
gene id: 211586:SO_RS19110
uniprot id: Q8E9Y8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.

211586:SO RS01350
gene id: 211586:SO_RS01350
uniprot id: Q8EK26
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits).
messages: In the C-terminal section; belongs to the transpeptidase family.
messages: In the N-terminal section; belongs to the glycosyltransferase 51 family.
messages: Membrane

211586:SO RS20640
gene id: 211586:SO_RS20640
uniprot id: Q8E945
names: Similarity
messages: Belongs to the bacterial solute-binding protein ModA family.

211586:SO RS09210
gene id: 211586:SO_RS09210
uniprot id: Q8EFH7
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

211586:SO RS11920
gene id: 211586:SO_RS11920
uniprot id: Q8EE02
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

211586:SO RS13550
gene id: 211586:SO_RS13550
uniprot id: Q8ED48
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. SDR39U1 subfamily.

211586:SO RS17900
gene id: 211586:SO_RS17900
uniprot id: K4PW18
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

211586:SO RS17480
gene id: 211586:SO_RS17480
uniprot id: Q8CME4
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

211586:SO RS12040
gene id: 211586:SO_RS12040
uniprot id: Q8EDX8
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

211586:SO RS07420
gene id: 211586:SO_RS07420
uniprot id: Q8EGJ5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

211586:SO RS04615
gene id: 211586:SO_RS04615
uniprot id: Q8EI63
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

211586:SO RS13565
gene id: 211586:SO_RS13565
uniprot id: Q8ED44
names: Subcellular Location Annotation
messages: Membrane

211586:SO RS17700
gene id: 211586:SO_RS17700
uniprot id: Q8EAU2
names: Similarity
messages: Belongs to the peptidase S8 family.

211586:SO RS21360
gene id: 211586:SO_RS21360
uniprot id: Q8E8R3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

211586:SO RS04310
gene id: 211586:SO_RS04310
uniprot id: Q8EIC4
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

211586:SO RS01490
gene id: 211586:SO_RS01490
uniprot id: Q8EJZ5
names: Cofactor
names: Similarity
messages: Belongs to the UPF0313 family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

211586:SO RS13170
gene id: 211586:SO_RS13170
uniprot id: Q8EDB8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SbcD family.
messages: Heterodimer of SbcC and SbcD.
messages: SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity.

211586:SO RS05975
gene id: 211586:SO_RS05975
uniprot id: Q8EHD7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

211586:SO RS02335
gene id: 211586:SO_RS02335
uniprot id: Q8EJH7
names: Subcellular Location Annotation
messages: Membrane

211586:SO RS15230
gene id: 211586:SO_RS15230
uniprot id: Q8EC82
names: Similarity
messages: Belongs to the TPP enzyme family.

211586:SO RS00110
gene id: 211586:SO_RS00110
uniprot id: Q8EKR8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M24B family. Bacterial-type prolidase subfamily.
messages: Binds 2 manganese ions per subunit.
messages: Splits dipeptides with a prolyl residue in the C-terminal position.

211586:SO RS21305
gene id: 211586:SO_RS21305
uniprot id: Q8E8S5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell inner membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. SRP is a ribonucleoprotein composed of Ffh and a 4.5S RNA molecule.

211586:SO RS15105
gene id: 211586:SO_RS15105
uniprot id: Q8ECA6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

211586:SO RS02760
gene id: 211586:SO_RS02760
uniprot id: Q8EJ86
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TPMT family.
messages: Cytoplasm

211586:SO RS18945
gene id: 211586:SO_RS18945
uniprot id: Q8EA22
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

211586:SO RS19700
gene id: 211586:SO_RS19700
uniprot id: Q8E9M2
names: Similarity
messages: Belongs to the UPF0758 family.

211586:SO RS04115
gene id: 211586:SO_RS04115
uniprot id: Q8EIG3
names: Similarity
messages: Belongs to the peptidase M17 family.

211586:SO RS03665
gene id: 211586:SO_RS03665
uniprot id: Q8EIR0
names: Similarity
messages: Belongs to the UbiH/COQ6 family.

211586:SO RS01420
gene id: 211586:SO_RS01420
uniprot id: Q8EK12
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm
messages: Homodimer.

211586:SO RS05645
gene id: 211586:SO_RS05645
uniprot id: K4PU03
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
messages: Cytoplasm
messages: Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.

211586:SO RS22535
gene id: 211586:SO_RS22535
uniprot id: Q8E848
names: Similarity
messages: Belongs to the site-specific recombinase resolvase family.

211586:SO RS04070
gene id: 211586:SO_RS04070
uniprot id: Q8EIH2
names: Similarity
messages: Belongs to the peptidase S8 family.

211586:SO RS09615
gene id: 211586:SO_RS09615
uniprot id: Q8EF94
names: Similarity
messages: Belongs to the HypD family.

211586:SO RS22040
gene id: 211586:SO_RS22040
uniprot id: Q8E8C7
names: Caution
names: Function
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family. MenB subfamily.
messages: Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2-naphthoyl-CoA (DHNA-CoA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

211586:SO RS09455
gene id: 211586:SO_RS09455
uniprot id: Q8EFC8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

211586:SO RS21235
gene id: 211586:SO_RS21235
uniprot id: Q8E8T6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

211586:SO RS20760
gene id: 211586:SO_RS20760
uniprot id: Q8E919
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. FieF subfamily.
messages: Cell inner membrane
messages: Cytoplasmic zinc binding may trigger movements of two electrically repulsive cytoplasmic domains and reorient transmembrane helices, thereby modulating coordination geometry of the active site for zinc transport. It may modulate activity in response to cytoplasmic metal fluctuations.
messages: Divalent metal cation transporter which exports Zn(2+), Cd(2+) and possibly Fe(2+) (PubMed:23341604, PubMed:29507252). Zn(2+)/H(+) antiporter capable of using the proton motive force to remove Zn(2+) from the cytoplasm (PubMed:34254979). May be involved in zinc and iron detoxification by efflux (By similarity).
messages: Homodimer (PubMed:29507252). The subunits are held together in a parallel orientation through zinc binding at the interface of the cytoplasmic domains (By similarity).

211586:SO RS12820
gene id: 211586:SO_RS12820
uniprot id: Q8EDI1
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

211586:SO RS20665
gene id: 211586:SO_RS20665
uniprot id: Q8E940
names: Cofactor
names: Function
messages: Accepts electrons from ETF and reduces ubiquinone.
messages: Binds 1 [4Fe-4S] cluster.

211586:SO RS14520
gene id: 211586:SO_RS14520
uniprot id: Q8ECK9
names: Subcellular Location Annotation
messages: Membrane

211586:SO RS03330
gene id: 211586:SO_RS03330
uniprot id: Q8CX49
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

211586:SO RS10980
gene id: 211586:SO_RS10980
uniprot id: Q8EEI7
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

211586:SO RS02810
gene id: 211586:SO_RS02810
uniprot id: Q8EJ78
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-to-5' exoribonuclease specific for small oligoribonucleotides.
messages: Belongs to the oligoribonuclease family.
messages: Cytoplasm

211586:SO RS14640
gene id: 211586:SO_RS14640
uniprot id: Q8ECJ9
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

211586:SO RS14220
gene id: 211586:SO_RS14220
uniprot id: Q8ECR7
names: Subcellular Location Annotation
messages: Membrane

211586:SO RS10120
gene id: 211586:SO_RS10120
uniprot id: Q8EF04
names: Similarity
messages: Belongs to the UPF0438 family.

211586:SO RS00050
gene id: 211586:SO_RS00050
uniprot id: Q8EKT0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

211586:SO RS08395
gene id: 211586:SO_RS08395
uniprot id: Q8EFY9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

211586:SO RS00035
gene id: 211586:SO_RS00035
uniprot id: Q8EKT3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

211586:SO RS07810
gene id: 211586:SO_RS07810
uniprot id: Q8EGB1
names: Similarity
messages: Belongs to the oxygen-dependent FAD-linked oxidoreductase family.

211586:SO RS21955
gene id: 211586:SO_RS21955
uniprot id: Q8E8E2
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

211586:SO RS20720
gene id: 211586:SO_RS20720
uniprot id: Q8E927
names: Function
names: Similarity
messages: Belongs to the nucleoside phosphorylase PpnP family.
messages: Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions.

211586:SO RS03685
gene id: 211586:SO_RS03685
uniprot id: Q8EIQ6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

211586:SO RS03285
gene id: 211586:SO_RS03285
uniprot id: Q8EIY4
names: Similarity
messages: Belongs to the aldose epimerase family.

211586:SO RS00790
gene id: 211586:SO_RS00790
uniprot id: Q8EKC4
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GSP I family.
messages: Cell inner membrane
messages: Cleaved by prepilin peptidase.
messages: Component of the type II secretion system required for the energy-dependent secretion of extracellular factors such as proteases and toxins from the periplasm.
messages: Membrane
messages: Type II secretion is composed of four main components: the outer membrane complex, the inner membrane complex, the cytoplasmic secretion ATPase and the periplasm-spanning pseudopilus.

211586:SO RS01260
gene id: 211586:SO_RS01260
uniprot id: Q8EK40
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. CcmA exporter (TC 3.A.1.107) family.
messages: Cell inner membrane
messages: Part of the ABC transporter complex CcmAB involved in the biogenesis of c-type cytochromes; once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system.
messages: The complex is composed of two ATP-binding proteins (CcmA) and two transmembrane proteins (CcmB).

211586:SO RS14975
gene id: 211586:SO_RS14975
uniprot id: Q8ECD3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sigma-70 factor family. FliA subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor controls the expression of flagella-related genes.

211586:SO RS20525
gene id: 211586:SO_RS20525
uniprot id: K4PW20
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

211586:SO RS03905
gene id: 211586:SO_RS03905
uniprot id: Q8EIK8
names: Cofactor
names: Similarity
messages: Belongs to the prokaryotic GSH synthase family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

211586:SO RS21205
gene id: 211586:SO_RS21205
uniprot id: Q8E8U2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane
messages: Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins.

211586:SO RS21785
gene id: 211586:SO_RS21785
uniprot id: Q8E8H7
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

211586:SO RS06095
gene id: 211586:SO_RS06095
uniprot id: Q8EHB4
names: Subcellular Location Annotation
messages: Membrane

211586:SO RS12495
gene id: 211586:SO_RS12495
uniprot id: Q8EDN7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinylarginine dihydrolase family.
messages: Catalyzes the hydrolysis of N(2)-succinylarginine into N(2)-succinylornithine, ammonia and CO(2).
messages: Homodimer.

211586:SO RS00315
gene id: 211586:SO_RS00315
uniprot id: Q8EKN1
names: Similarity
messages: Belongs to the peptidase C40 family.

211586:SO RS22880
gene id: 211586:SO_RS22880
uniprot id: Q8E800
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.

211586:SO RS08580
gene id: 211586:SO_RS08580
uniprot id: Q8EFV4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

211586:SO RS04085
gene id: 211586:SO_RS04085
uniprot id: Q8EIG9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

211586:SO RS01415
gene id: 211586:SO_RS01415
uniprot id: Q8EK13
names: Function
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family.
messages: Specifically catalyzes the dephosphorylation of 2-phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress.

211586:SO RS12090
gene id: 211586:SO_RS12090
uniprot id: Q8EDW8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L/F-transferase family.
messages: Cytoplasm
messages: Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.

211586:SO RS12745
gene id: 211586:SO_RS12745
uniprot id: Q8EDJ4
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

211586:SO RS11235
gene id: 211586:SO_RS11235
uniprot id: Q8EED4
names: Similarity
messages: Belongs to the Nudix hydrolase family.

211586:SO RS08285
gene id: 211586:SO_RS08285
uniprot id: Q8EG11
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

211586:SO RS12895
gene id: 211586:SO_RS12895
uniprot id: K4PU25
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

211586:SO RS04195
gene id: 211586:SO_RS04195
uniprot id: Q8EIE7
names: Similarity
messages: Belongs to the pirin family.

211586:SO RS07750
gene id: 211586:SO_RS07750
uniprot id: Q8EGC5
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

211586:SO RS18780
gene id: 211586:SO_RS18780
uniprot id: Q8EA66
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

211586:SO RS06900
gene id: 211586:SO_RS06900
uniprot id: Q8EGV7
names: Cofactor
messages: Can also use Mn(2+) ion.

211586:SO RS12835
gene id: 211586:SO_RS12835
uniprot id: Q8EDH7
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

211586:SO RS22615
gene id: 211586:SO_RS22615
uniprot id: Q8E838
names: Function
messages: Involved in the transposition of the insertion sequence.

211586:SO RS06275
gene id: 211586:SO_RS06275
uniprot id: Q8EH77
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Cytoplasm
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

211586:SO RS19630
gene id: 211586:SO_RS19630
uniprot id: Q8E9N5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 1 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

211586:SO RS07095
gene id: 211586:SO_RS07095
uniprot id: K4PTY3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

211586:SO RS08380
gene id: 211586:SO_RS08380
uniprot id: Q8EFZ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Gram-negative porin family.
messages: Cell outer membrane
messages: Membrane

211586:SO RS09250
gene id: 211586:SO_RS09250
uniprot id: Q8EFG7
names: Function
names: Similarity
messages: Belongs to the Dus family. DusC subfamily.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U16 in tRNAs.

211586:SO RS18485
gene id: 211586:SO_RS18485
uniprot id: Q8EAD3
names: Similarity
messages: Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family.

211586:SO RS16015
gene id: 211586:SO_RS16015
uniprot id: Q8EBS2
names: Similarity
messages: Belongs to the aspartokinase family.

211586:SO RS02130
gene id: 211586:SO_RS02130
uniprot id: Q8EJM1
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

211586:SO RS18110
gene id: 211586:SO_RS18110
uniprot id: Q8EAL2
names: Similarity
messages: Belongs to the hemerythrin family.
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

211586:SO RS14000
gene id: 211586:SO_RS14000
uniprot id: Q8ECV4
names: Cofactor
names: Similarity
messages: Belongs to the anthranilate synthase component I family.
messages: Binds 1 Mg(2+) ion per subunit.

211586:SO RS01705
gene id: 211586:SO_RS01705
uniprot id: Q8CME4
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

211586:SO RS11270
gene id: 211586:SO_RS11270
uniprot id: Q8EEC7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

211586:SO RS21660
gene id: 211586:SO_RS21660
uniprot id: Q8E8K5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RlmJ family.
messages: Monomer.
messages: Specifically methylates the adenine in position 2030 of 23S rRNA.

211586:SO RS12070
gene id: 211586:SO_RS12070
uniprot id: Q8EDX2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.

211586:SO RS21665
gene id: 211586:SO_RS21665
uniprot id: Q8E8K4
names: Similarity
messages: Belongs to the transglycosylase Slt family.

211586:SO RS01750
gene id: 211586:SO_RS01750
uniprot id: Q8EJU2
names: Subcellular Location Annotation
messages: Membrane

211586:SO RS14215
gene id: 211586:SO_RS14215
uniprot id: Q8ECR8
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

211586:SO RS11985
gene id: 211586:SO_RS11985
uniprot id: Q8EDY8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ProQ family.
messages: Cytoplasm
messages: RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities.

211586:SO RS10640
gene id: 211586:SO_RS10640
uniprot id: Q8CMJ3
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

211586:SO RS07210
gene id: 211586:SO_RS07210
uniprot id: Q8EGP3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RdgC family.
messages: May be involved in recombination.
messages: nucleoid

211586:SO RS09405
gene id: 211586:SO_RS09405
uniprot id: Q8EFD9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MsrP family.
messages: Binds 1 Mo-molybdopterin (Mo-MPT) cofactor per subunit.
messages: Heterodimer of a catalytic subunit (MsrP) and a heme-binding subunit (MsrQ).
messages: Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide.
messages: Periplasm

211586:SO RS02170
gene id: 211586:SO_RS02170
uniprot id: Q8EJL1
names: Similarity
messages: Belongs to the thioredoxin family.

211586:SO RS19210
gene id: 211586:SO_RS19210
uniprot id: Q8E9W6
names: Subcellular Location Annotation
messages: Membrane

211586:SO RS16085
gene id: 211586:SO_RS16085
uniprot id: Q8EBQ9
names: Activity Regulation
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.

211586:SO RS02520
gene id: 211586:SO_RS02520
uniprot id: Q8EJD8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

211586:SO RS20655
gene id: 211586:SO_RS20655
uniprot id: Q8E942
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MoaC family.
messages: Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
messages: Homohexamer; trimer of dimers.

211586:SO RS19665
gene id: 211586:SO_RS19665
uniprot id: Q8E9M8
names: Similarity
messages: Belongs to the helicase family. RecQ subfamily.

211586:SO RS06675
gene id: 211586:SO_RS06675
uniprot id: Q8CMJ3
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

211586:SO RS21690
gene id: 211586:SO_RS21690
uniprot id: Q8E8J8
names: PTM
messages: Binds 2 heme c groups covalently per subunit.

211586:SO RS16995
gene id: 211586:SO_RS16995
uniprot id: Q8EB93
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

211586:SO RS01890
gene id: 211586:SO_RS01890
uniprot id: Q8EJR9
names: Function
names: Similarity
names: Subunit
messages: Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters.
messages: Belongs to the transcriptional regulatory Fis family.
messages: Homodimer.

211586:SO RS01455
gene id: 211586:SO_RS01455
uniprot id: Q8EK05
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

211586:SO RS00955
gene id: 211586:SO_RS00955
uniprot id: Q8EK90
names: Function
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.
messages: Provides the (R)-glutamate required for cell wall biosynthesis.

211586:SO RS16070
gene id: 211586:SO_RS16070
uniprot id: Q8EBR2
names: Function
names: Similarity
messages: Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).

211586:SO RS04060
gene id: 211586:SO_RS04060
uniprot id: Q8EIH4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CsgA/CsgB family.
messages: Fimbrium

211586:SO RS21015
gene id: 211586:SO_RS21015
uniprot id: Q8E8X7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

211586:SO RS17420
gene id: 211586:SO_RS17420
uniprot id: Q8EAZ6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PNT beta subunit family.
messages: Cell inner membrane
messages: Heterodimer of an alpha and a beta chain.
messages: Membrane
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

211586:SO RS06960
gene id: 211586:SO_RS06960
uniprot id: Q8EGU1
names: Subcellular Location Annotation
messages: Membrane

211586:SO RS04995
gene id: 211586:SO_RS04995
uniprot id: Q8EHX9
names: Function
names: Similarity
messages: Belongs to the peptidase S46 family.
messages: Catalyzes the removal of dipeptides from the N-terminus of oligopeptides.

211586:SO RS02885
gene id: 211586:SO_RS02885
uniprot id: Q8EJ66
names: Function
names: Similarity
messages: Belongs to the band 7/mec-2 family. HflC subfamily.
messages: HflC and HflK could regulate a protease.

211586:SO RS18535
gene id: 211586:SO_RS18535
uniprot id: Q8EAC3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Membrane

211586:SO RS04105
gene id: 211586:SO_RS04105
uniprot id: Q8EIG5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DksA family.
messages: Cytoplasm
messages: Interacts directly with the RNA polymerase.
messages: Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters. Also required for regulation of fis expression.

211586:SO RS20175
gene id: 211586:SO_RS20175
uniprot id: Q8E9E1
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

211586:SO RS14075
gene id: 211586:SO_RS14075
uniprot id: Q8ECT8
names: Similarity
messages: Belongs to the YciI family.

211586:SO RS09460
gene id: 211586:SO_RS09460
uniprot id: Q8EFC7
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.

211586:SO RS17405
gene id: 211586:SO_RS17405
uniprot id: Q8EB00
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Alpha(8)-beta(8). The alpha component is a flavoprotein, the beta component is a hemoprotein.
messages: Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Binds 1 siroheme per subunit.
messages: Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate.

211586:SO RS18930
gene id: 211586:SO_RS18930
uniprot id: Q8EA29
names: Similarity
messages: Belongs to the intimin/invasin family.

211586:SO RS01715
gene id: 211586:SO_RS01715
uniprot id: Q8EJU9
names: Similarity
messages: Belongs to the RutC family.

211586:SO RS05160
gene id: 211586:SO_RS05160
uniprot id: Q8EHU9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

211586:SO RS01410
gene id: 211586:SO_RS01410
uniprot id: Q8EK14
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

211586:SO RS07925
gene id: 211586:SO_RS07925
uniprot id: Q8EG84
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

211586:SO RS11650
gene id: 211586:SO_RS11650
uniprot id: Q8EE60
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

211586:SO RS19970
gene id: 211586:SO_RS19970
uniprot id: Q8E9H5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.

211586:SO RS09605
gene id: 211586:SO_RS09605
uniprot id: Q8EF96
names: Function
names: Similarity
messages: Belongs to the HypA/HybF family.
messages: Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.

211586:SO RS01140
gene id: 211586:SO_RS01140
uniprot id: Q8EK61
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

211586:SO RS13505
gene id: 211586:SO_RS13505
uniprot id: Q8ED57
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Activation of pyruvate formate-lyase 1 under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.
messages: Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.
messages: Belongs to the organic radical-activating enzymes family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm

211586:SO RS07560
gene id: 211586:SO_RS07560
uniprot id: Q8EGG7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamA family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

211586:SO RS05210
gene id: 211586:SO_RS05210
uniprot id: Q8EHT6
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

211586:SO RS11610
gene id: 211586:SO_RS11610
uniprot id: Q8EE66
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

211586:SO RS10715
gene id: 211586:SO_RS10715
uniprot id: Q8EEP0
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

211586:SO RS13675
gene id: 211586:SO_RS13675
uniprot id: Q8ED23
names: Similarity
messages: Belongs to the peptidase C40 family.

211586:SO RS21365
gene id: 211586:SO_RS21365
uniprot id: Q8E8R2
names: Similarity
messages: Belongs to the RNase T2 family.

211586:SO RS13430
gene id: 211586:SO_RS13430
uniprot id: Q8ED69
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ZipA family.
messages: Cell inner membrane
messages: Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins.
messages: Interacts with FtsZ via their C-terminal domains.

211586:SO RS04025
gene id: 211586:SO_RS04025
uniprot id: Q8EII1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell inner membrane
messages: Membrane

211586:SO RS20185
gene id: 211586:SO_RS20185
uniprot id: Q8E9D9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.

211586:SO RS06950
gene id: 211586:SO_RS06950
uniprot id: Q8EGU3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
messages: Homotetramer.
messages: Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc.

211586:SO RS12550
gene id: 211586:SO_RS12550
uniprot id: Q8EDM4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PNP/UDP phosphorylase family.
messages: Catalyzes the reversible phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.
messages: Homohexamer; trimer of homodimers.

211586:SO RS10560
gene id: 211586:SO_RS10560
uniprot id: Q8EER6
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

211586:SO RS21915
gene id: 211586:SO_RS21915
uniprot id: Q8E8F0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily.
messages: Cell inner membrane
messages: Involved in the import of queuosine (Q) precursors, required for Q precursor salvage.

211586:SO RS14160
gene id: 211586:SO_RS14160
uniprot id: Q8ECT0
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

211586:SO RS19730
gene id: 211586:SO_RS19730
uniprot id: Q8E9L5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.

211586:SO RS16720
gene id: 211586:SO_RS16720
uniprot id: Q8EBE5
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

211586:SO RS09275
gene id: 211586:SO_RS09275
uniprot id: Q8EFG1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

211586:SO RS19915
gene id: 211586:SO_RS19915
uniprot id: Q8E9I4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family.
messages: Membrane

211586:SO RS04240
gene id: 211586:SO_RS04240
uniprot id: Q8EID6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell inner membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: Membrane
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

211586:SO RS05435
gene id: 211586:SO_RS05435
uniprot id: Q8EHP1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CN hydrolase family. Apolipoprotein N-acyltransferase subfamily.
messages: Catalyzes the phospholipid dependent N-acylation of the N-terminal cysteine of apolipoprotein, the last step in lipoprotein maturation.
messages: Cell inner membrane

211586:SO RS05640
gene id: 211586:SO_RS05640
uniprot id: Q8EHL0
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cell membrane
messages: Homodimer.
messages: May be involved in cell division.

211586:SO RS02315
gene id: 211586:SO_RS02315
uniprot id: Q8EJI1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NrfD family.
messages: Membrane

211586:SO RS17330
gene id: 211586:SO_RS17330
uniprot id: Q8EB18
names: Similarity
messages: Belongs to the thioredoxin family. DsbA subfamily.

211586:SO RS01965
gene id: 211586:SO_RS01965
uniprot id: Q8EJQ5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DEAD box helicase family. RhlB subfamily.
messages: Component of the RNA degradosome, which is a multiprotein complex involved in RNA processing and mRNA degradation.
messages: Cytoplasm
messages: DEAD-box RNA helicase involved in RNA degradation. Has RNA-dependent ATPase activity and unwinds double-stranded RNA.

211586:SO RS12760
gene id: 211586:SO_RS12760
uniprot id: Q8EDJ2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase T family.
messages: Binds two Mg(2+) per subunit. The active form of the enzyme binds two Mg(2+) ions in its active site. The first Mg(2+) forms only one salt bridge with the protein.
messages: Homodimer.
messages: Trims short 3' overhangs of a variety of RNA species, leaving a one or two nucleotide 3' overhang. Responsible for the end-turnover of tRNA: specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis.

211586:SO RS02045
gene id: 211586:SO_RS02045
uniprot id: Q8EJN8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 3 lipoyl cofactors covalently.
messages: Forms a 24-polypeptide structural core with octahedral symmetry.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).

211586:SO RS16240
gene id: 211586:SO_RS16240
uniprot id: Q8EBN6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

211586:SO RS04950
gene id: 211586:SO_RS04950
uniprot id: Q8EHY9
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

211586:SO RS12850
gene id: 211586:SO_RS12850
uniprot id: Q8EDH4
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

211586:SO RS08290
gene id: 211586:SO_RS08290
uniprot id: Q8EG10
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

211586:SO RS01090
gene id: 211586:SO_RS01090
uniprot id: Q8EK70
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

211586:SO RS14195
gene id: 211586:SO_RS14195
uniprot id: Q8ECS2
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

211586:SO RS10315
gene id: 211586:SO_RS10315
uniprot id: Q8EEW4
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

211586:SO RS05885
gene id: 211586:SO_RS05885
uniprot id: Q8CMJ3
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

211586:SO RS13290
gene id: 211586:SO_RS13290
uniprot id: Q8ED96
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

211586:SO RS11790
gene id: 211586:SO_RS11790
uniprot id: Q8EE30
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase H family.
messages: Binds 1 Mg(2+) ion per subunit. May bind a second metal ion at a regulatory site, or after substrate binding.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Monomer.

211586:SO RS11140
gene id: 211586:SO_RS11140
uniprot id: Q8EEF2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvA family.
messages: Cytoplasm
messages: Has three domains with a flexible linker between the domains II and III and assumes an 'L' shape. Domain III is highly mobile and contacts RuvB.
messages: Homotetramer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

211586:SO RS18585
gene id: 211586:SO_RS18585
uniprot id: Q8EAB0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0114 family.
messages: Cell membrane

211586:SO RS10760
gene id: 211586:SO_RS10760
uniprot id: Q8EEN1
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

211586:SO RS07230
gene id: 211586:SO_RS07230
uniprot id: Q8EGN9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PstS family.
messages: Involved in the system for phosphate transport across the cytoplasmic membrane.
messages: Periplasm
messages: Secreted

211586:SO RS06365
gene id: 211586:SO_RS06365
uniprot id: Q8EH60
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptF/LptG family.
messages: Component of the lipopolysaccharide transport and assembly complex. The LptBFG transporter is composed of two ATP-binding proteins (LptB) and two transmembrane proteins (LptF and LptG).
messages: Membrane
messages: Part of the ABC transporter complex LptBFG involved in the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane.

211586:SO RS11090
gene id: 211586:SO_RS11090
uniprot id: Q8EEG4
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

211586:SO RS04725
gene id: 211586:SO_RS04725
uniprot id: Q8EI38
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell inner membrane
messages: NDH-1 is composed of 13 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

211586:SO RS10180
gene id: 211586:SO_RS10180
uniprot id: Q8EEZ4
names: Caution
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

211586:SO RS05980
gene id: 211586:SO_RS05980
uniprot id: Q8EHD6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

211586:SO RS20745
gene id: 211586:SO_RS20745
uniprot id: Q8E922
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Member of the two-component regulatory system NtrB/NtrC, which controls expression of the nitrogen-regulated (ntr) genes in response to nitrogen limitation. Phosphorylated NtrC binds directly to DNA and stimulates the formation of open promoter-sigma54-RNA polymerase complexes.

211586:SO RS16705
gene id: 211586:SO_RS16705
uniprot id: Q8EBE8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

211586:SO RS15570
gene id: 211586:SO_RS15570
uniprot id: Q8EC05
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Cell inner membrane
messages: Homoheptamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mechanosensitive channel that participates in the regulation of osmotic pressure changes within the cell, opening in response to stretch forces in the membrane lipid bilayer, without the need for other proteins. Contributes to normal resistance to hypoosmotic shock. Forms an ion channel of 1.0 nanosiemens conductance with a slight preference for anions.
messages: Membrane

211586:SO RS02175
gene id: 211586:SO_RS02175
uniprot id: Q8EJL0
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

211586:SO RS19555
gene id: 211586:SO_RS19555
uniprot id: Q8E9P8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

211586:SO RS15340
gene id: 211586:SO_RS15340
uniprot id: Q8EC58
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Cell inner membrane
messages: Membrane

211586:SO RS03525
gene id: 211586:SO_RS03525
uniprot id: Q8EIT7
names: Similarity
messages: Belongs to the ferredoxin--NADP reductase type 1 family.

211586:SO RS19690
gene id: 211586:SO_RS19690
uniprot id: Q8E9M4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

211586:SO RS06115
gene id: 211586:SO_RS06115
uniprot id: Q8EHB0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0126 family.
messages: Membrane

211586:SO RS07290
gene id: 211586:SO_RS07290
uniprot id: Q8EGM5
names: Caution
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

211586:SO RS12645
gene id: 211586:SO_RS12645
uniprot id: Q8EDK5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily.
messages: Catalyzes the transfer of the alpha-amino group from S-adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only aminotransferase known to utilize SAM as an amino donor.
messages: Cytoplasm
messages: Homodimer.

211586:SO RS09525
gene id: 211586:SO_RS09525
uniprot id: Q8EFB2
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

211586:SO RS21530
gene id: 211586:SO_RS21530
uniprot id: Q8E8M8
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

211586:SO RS21505
gene id: 211586:SO_RS21505
uniprot id: Q8E8N4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

211586:SO RS04720
gene id: 211586:SO_RS04720
uniprot id: Q8EI39
names: Subcellular Location Annotation
messages: Membrane

211586:SO RS08020
gene id: 211586:SO_RS08020
uniprot id: Q8EG61
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TerC family.
messages: Membrane

211586:SO RS18920
gene id: 211586:SO_RS18920
uniprot id: Q8EA31
names: Similarity
messages: Belongs to the peptidase U62 family.

211586:SO RS16495
gene id: 211586:SO_RS16495
uniprot id: Q8EBI7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

211586:SO RS10685
gene id: 211586:SO_RS10685
uniprot id: Q8EEP7
names: Function
names: Similarity
messages: Belongs to the flavodoxin family.
messages: Low-potential electron donor to a number of redox enzymes.

211586:SO RS15815
gene id: 211586:SO_RS15815
uniprot id: Q8EBV7
names: Similarity
messages: Belongs to the DEAD box helicase family.

211586:SO RS09650
gene id: 211586:SO_RS09650
uniprot id: Q8EF87
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.
messages: Cell membrane
messages: Heterodimer of a large and a small subunit.

211586:SO RS21410
gene id: 211586:SO_RS21410
uniprot id: Q8E8Q2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Membrane

211586:SO RS02005
gene id: 211586:SO_RS02005
uniprot id: Q8EJP7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Cell inner membrane
messages: Membrane

211586:SO RS19995
gene id: 211586:SO_RS19995
uniprot id: Q8E9H0
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HMBS family.
messages: Binds 1 dipyrromethane group covalently.
messages: Monomer.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
messages: The porphobilinogen subunits are added to the dipyrromethane group.

211586:SO RS14230
gene id: 211586:SO_RS14230
uniprot id: Q8ECR5
names: Function
names: Similarity
messages: Belongs to the folylpolyglutamate synthase family.
messages: Functions in two distinct reactions of the de novo folate biosynthetic pathway. Catalyzes the addition of a glutamate residue to dihydropteroate (7,8-dihydropteroate or H2Pte) to form dihydrofolate (7,8-dihydrofolate monoglutamate or H2Pte-Glu). Also catalyzes successive additions of L-glutamate to tetrahydrofolate or 10-formyltetrahydrofolate or 5,10-methylenetetrahydrofolate, leading to folylpolyglutamate derivatives.

211586:SO RS01245
gene id: 211586:SO_RS01245
uniprot id: Q8EK43
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmD/CycX/HelD family.
messages: Cell inner membrane
messages: Membrane
messages: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.

211586:SO RS10335
gene id: 211586:SO_RS10335
uniprot id: Q8EEW0
names: Similarity
messages: Belongs to the acylphosphatase family.

211586:SO RS14995
gene id: 211586:SO_RS14995
uniprot id: Q8ECC8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type III secretion exporter family.
messages: Cell membrane
messages: Membrane
messages: Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

211586:SO RS15350
gene id: 211586:SO_RS15350
uniprot id: Q8EC56
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: In the C-terminal section; belongs to the transglycosylase Slt family.
messages: In the N-terminal section; belongs to the bacterial solute-binding protein 3 family.
messages: Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella.
messages: The N-terminal domain does not have lytic activity and probably modulates enzymatic activity. The C-terminal domain is the catalytic active domain.

211586:SO RS00075
gene id: 211586:SO_RS00075
uniprot id: Q8EKS5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

211586:SO RS22095
gene id: 211586:SO_RS22095
uniprot id: Q8E8B6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell inner membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.

211586:SO RS04200
gene id: 211586:SO_RS04200
uniprot id: Q8EIE5
names: Similarity
messages: Belongs to the DEAD box helicase family.

211586:SO RS13520
gene id: 211586:SO_RS13520
uniprot id: Q8ED54
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Homohexamer.
messages: In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.
messages: In the N-terminal section; belongs to the CobB/CobQ family.
messages: Involved in acetate metabolism.
messages: The N-terminal region seems to be important for proper quaternary structure. The C-terminal region contains the substrate-binding site.

211586:SO RS18985
gene id: 211586:SO_RS18985
uniprot id: Q8EA14
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YhdE subfamily.
messages: Cytoplasm
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

211586:SO RS17340
gene id: 211586:SO_RS17340
uniprot id: Q8EB16
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HemG family.
messages: Binds 1 FMN non-covalently per subunit.
messages: Catalyzes the 6-electron oxidation of protoporphyrinogen IX to form protoporphyrin IX; under anaerobic conditions uses menaquinone as an electron acceptor, under aerobic conditions uses ubiquinone as an electron acceptor.
messages: Cell inner membrane

211586:SO RS21380
gene id: 211586:SO_RS21380
uniprot id: Q8E8Q9
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPAT/DAPAT family.
messages: Cell inner membrane
messages: The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate.

211586:SO RS06170
gene id: 211586:SO_RS06170
uniprot id: Q8EH98
names: Function
names: Similarity
messages: Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage.
messages: Belongs to the Nudix hydrolase family. RppH subfamily.

211586:SO RS21710
gene id: 211586:SO_RS21710
uniprot id: Q8E8J3
names: Subcellular Location Annotation
messages: Membrane

211586:SO RS08630
gene id: 211586:SO_RS08630
uniprot id: Q8EFU8
names: Similarity
messages: Belongs to the UPF0502 family.

211586:SO RS05655
gene id: 211586:SO_RS05655
uniprot id: Q8EHK7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family.
messages: Membrane

211586:SO RS12080
gene id: 211586:SO_RS12080
uniprot id: Q8EDX0
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

211586:SO RS09590
gene id: 211586:SO_RS09590
uniprot id: Q8EF99
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

211586:SO RS16665
gene id: 211586:SO_RS16665
uniprot id: Q8EBF3
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

211586:SO RS11975
gene id: 211586:SO_RS11975
uniprot id: Q8EDZ0
names: Similarity
messages: Belongs to the peptidase M1 family.

211586:SO RS14245
gene id: 211586:SO_RS14245
uniprot id: Q8ECR3
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

211586:SO RS14185
gene id: 211586:SO_RS14185
uniprot id: Q8ECS4
names: Similarity
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.

211586:SO RS01930
gene id: 211586:SO_RS01930
uniprot id: Q8EJR1
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily.

211586:SO RS12635
gene id: 211586:SO_RS12635
uniprot id: Q8EDK7
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.

211586:SO RS18305
gene id: 211586:SO_RS18305
uniprot id: Q8EAG9
names: Subcellular Location Annotation
messages: Membrane

211586:SO RS00665
gene id: 211586:SO_RS00665
uniprot id: Q8EKF4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferritin family. Prokaryotic subfamily.
messages: Cytoplasm
messages: Iron-storage protein.

211586:SO RS17020
gene id: 211586:SO_RS17020
uniprot id: Q8EB86
names: Function
names: Similarity
messages: Belongs to the dihydrofolate reductase family.
messages: Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.

211586:SO RS02435
gene id: 211586:SO_RS02435
uniprot id: Q8EJF6
names: Function
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

211586:SO RS17115
gene id: 211586:SO_RS17115
uniprot id: Q8EB64
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

211586:SO RS15925
gene id: 211586:SO_RS15925
uniprot id: Q8EBT4
names: Similarity
names: Subunit
messages: Homotetramer.
messages: In the C-terminal section; belongs to the homoserine dehydrogenase family.
messages: In the N-terminal section; belongs to the aspartokinase family.

211586:SO RS13510
gene id: 211586:SO_RS13510
uniprot id: Q8ED56
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0208 family.
messages: Cell inner membrane

211586:SO RS19975
gene id: 211586:SO_RS19975
uniprot id: Q8E9H4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

211586:SO RS06070
gene id: 211586:SO_RS06070
uniprot id: Q8EHC1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aquaporins contain two tandem repeats each containing three membrane-spanning domains and a pore-forming loop with the signature motif Asn-Pro-Ala (NPA).
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Cell inner membrane
messages: Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity.
messages: Homotetramer.

211586:SO RS20000
gene id: 211586:SO_RS20000
uniprot id: Q8E9G9
names: Function
names: Similarity
messages: Belongs to the uroporphyrinogen-III synthase family.
messages: Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.

211586:SO RS12735
gene id: 211586:SO_RS12735
uniprot id: Q8EDJ6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ExbD/TolR family.
messages: Cell inner membrane
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

211586:SO RS11355
gene id: 211586:SO_RS11355
uniprot id: Q8EEB3
names: Function
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

211586:SO RS09885
gene id: 211586:SO_RS09885
uniprot id: Q8EF44
names: Function
names: Similarity
names: Subunit
messages: A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild-type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity.
messages: Belongs to the RecC family.
messages: Heterotrimer of RecB, RecC and RecD. All subunits contribute to DNA-binding.

211586:SO RS04030
gene id: 211586:SO_RS04030
uniprot id: Q8EII0
names: Subcellular Location Annotation
messages: Cell inner membrane

211586:SO RS10550
gene id: 211586:SO_RS10550
uniprot id: Q8EER8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-3 family.
messages: Cytoplasm
messages: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.
messages: Monomer.

211586:SO RS13455
gene id: 211586:SO_RS13455
uniprot id: Q8ED65
names: Subcellular Location Annotation
messages: Membrane

211586:SO RS20375
gene id: 211586:SO_RS20375
uniprot id: Q8CME4
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

211586:SO RS01955
gene id: 211586:SO_RS01955
uniprot id: Q8EJQ7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.

211586:SO RS04985
gene id: 211586:SO_RS04985
uniprot id: Q8EHY2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GbpA family.
messages: Probably interacts with GlcNAc residues. May promote attachment to both epithelial cell surfaces and chitin.
messages: Secreted

211586:SO RS07425
gene id: 211586:SO_RS07425
uniprot id: Q8EGJ4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family. QueF type 2 subfamily.
messages: Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
messages: Cytoplasm
messages: Homodimer.

211586:SO RS08680
gene id: 211586:SO_RS08680
uniprot id: Q8EFT8
names: Subcellular Location Annotation
messages: Cytoplasm

211586:SO RS10345
gene id: 211586:SO_RS10345
uniprot id: Q8EEV8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

211586:SO RS16615
gene id: 211586:SO_RS16615
uniprot id: Q8EBG3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)- to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Homodimer.

211586:SO RS01585
gene id: 211586:SO_RS01585
uniprot id: Q8EJX4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response.
messages: Belongs to the SrkA/RdoA protein kinase family.
messages: Cytoplasm
messages: Monomer.

211586:SO RS11570
gene id: 211586:SO_RS11570
uniprot id: Q8EE76
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell inner membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

211586:SO RS02790
gene id: 211586:SO_RS02790
uniprot id: Q8EJ80
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

211586:SO RS05265
gene id: 211586:SO_RS05265
uniprot id: Q8EHS5
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

211586:SO RS17535
gene id: 211586:SO_RS17535
uniprot id: Q8EAX8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the spermidine/spermine synthase family.
messages: Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
messages: Cell membrane
messages: Homodimer or homotetramer.

211586:SO RS19775
gene id: 211586:SO_RS19775
uniprot id: Q8E9K7
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

211586:SO RS01125
gene id: 211586:SO_RS01125
uniprot id: Q8EK63
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity).

211586:SO RS11810
gene id: 211586:SO_RS11810
uniprot id: Q8EE26
names: Similarity
messages: Belongs to the transglycosylase Slt family.

211586:SO RS19450
gene id: 211586:SO_RS19450
uniprot id: Q8E9R5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC1 family. UbiB subfamily.
messages: Cell inner membrane
messages: Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis.

211586:SO RS14775
gene id: 211586:SO_RS14775
uniprot id: Q8ECH2
names: Similarity
messages: Belongs to the HipA Ser/Thr kinase family.

211586:SO RS04840
gene id: 211586:SO_RS04840
uniprot id: Q8EI14
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Cob(I)alamin adenosyltransferase family.
messages: Cytoplasm
messages: Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids.

211586:SO RS01035
gene id: 211586:SO_RS01035
uniprot id: Q8EK80
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

211586:SO RS14990
gene id: 211586:SO_RS14990
uniprot id: Q8ECD0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.
messages: Cell membrane
messages: Membrane
messages: Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

211586:SO RS21620
gene id: 211586:SO_RS21620
uniprot id: Q8E8L0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the ABC transporter complex (TC 3.A.1.6.1) involved in sulfate/thiosulfate import.
messages: Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (CysA), two transmembrane proteins (CysT and CysW) and a solute-binding protein (CysP).

211586:SO RS14610
gene id: 211586:SO_RS14610
uniprot id: Q8ECK2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

211586:SO RS14120
gene id: 211586:SO_RS14120
uniprot id: Q8CMJ3
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

211586:SO RS21165
gene id: 211586:SO_RS21165
uniprot id: Q8E8V0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

211586:SO RS18995
gene id: 211586:SO_RS18995
uniprot id: Q8EA12
names: Similarity
messages: Belongs to the MreC family.

211586:SO RS21465
gene id: 211586:SO_RS21465
uniprot id: Q8CVD0
names: Cofactor
names: Disruption Phenotype
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
messages: Binds 1 FAD per subunit.
messages: Binds 1 FMN covalently per subunit.
messages: By urocanate under anaerobic conditions.
messages: Catalyzes the two-electron reduction of urocanate to dihydrourocanate (also named imidazole propionate or deamino-histidine). The physiological electron donor is unknown; it might be the membrane-bound tetraheme cytochrome c (CymA). Enables anaerobic growth with urocanate as a sole terminal electron acceptor, and thus can provide the cells with a niche where no other bacteria can compete and survive. Is unable to reduce cinnamate and other unsaturated organic acids such as acrylic, crotonic, fumaric and orotic acids. Has no fumarate reductase or succinate dehydrogenase activity.
messages: Cell membrane
messages: In the urdA-deficient strain, the urocanate reductase activity measured in the crude extract from cells anaerobically grown on a mixture of urocanate and fumarate (or urocanate and nitrate) is about 20-fold lower than in the wild-type. This strain is not affected in its ability to grow in the presence of fumarate, but fails to grow anaerobically on urocanate.

211586:SO RS16640
gene id: 211586:SO_RS16640
uniprot id: Q8EBF8
names: Similarity
messages: Belongs to the peptidase M16 family.

211586:SO RS15335
gene id: 211586:SO_RS15335
uniprot id: Q8EC59
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

211586:SO RS05420
gene id: 211586:SO_RS05420
uniprot id: Q8EHP4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm

211586:SO RS15560
gene id: 211586:SO_RS15560
uniprot id: Q8EC07
names: Similarity
names: Subunit
messages: Belongs to the threonine aldolase family.
messages: Homotetramer.

211586:SO RS16725
gene id: 211586:SO_RS16725
uniprot id: K4PU17
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

211586:SO RS02110
gene id: 211586:SO_RS02110
uniprot id: Q8EJM5
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

211586:SO RS21735
gene id: 211586:SO_RS21735
uniprot id: Q8E8I8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase group 1 family.
messages: Cell membrane
messages: Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP-Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A.

211586:SO RS13540
gene id: 211586:SO_RS13540
uniprot id: Q8ED50
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

211586:SO RS13295
gene id: 211586:SO_RS13295
uniprot id: Q8ED95
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

211586:SO RS06285
gene id: 211586:SO_RS06285
uniprot id: Q8EH75
names: Subcellular Location Annotation
messages: Membrane

211586:SO RS04800
gene id: 211586:SO_RS04800
uniprot id: Q8EI23
names: Domain
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 dependent methionine synthase family.
messages: Catalyzes the transfer of a methyl group from methyl-cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
messages: Modular enzyme with four functionally distinct domains. The isolated Hcy-binding domain catalyzes methyl transfer from free methylcobalamin to homocysteine. The Hcy-binding domain in association with the pterin-binding domain catalyzes the methylation of cob(I)alamin by methyltetrahydrofolate and the methylation of homocysteine. The B12-binding domain binds the cofactor. The AdoMet activation domain binds S-adenosyl-L-methionine. Under aerobic conditions cob(I)alamin can be converted to inactive cob(II)alamin. Reductive methylation by S-adenosyl-L-methionine and flavodoxin regenerates methylcobalamin.

211586:SO RS00310
gene id: 211586:SO_RS00310
uniprot id: Q8EKN2
names: Subcellular Location Annotation
messages: Membrane

211586:SO RS12655
gene id: 211586:SO_RS12655
uniprot id: Q8EDK3
names: Function
names: PTM
names: Similarity
messages: Acetylated. Deacetylation by the SIR2-homolog deacetylase activates the enzyme.
messages: Belongs to the ATP-dependent AMP-binding enzyme family.
messages: Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.

211586:SO RS09620
gene id: 211586:SO_RS09620
uniprot id: Q8EF93
names: Similarity
messages: Belongs to the HupF/HypC family.

211586:SO RS01625
gene id: 211586:SO_RS01625
uniprot id: Q8EJW6
names: Function
names: Similarity
messages: Acts on leucine, isoleucine and valine.
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

211586:SO RS15665
gene id: 211586:SO_RS15665
uniprot id: Q8EBY5
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

211586:SO RS05920
gene id: 211586:SO_RS05920
uniprot id: Q8EHE7
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

211586:SO RS05280
gene id: 211586:SO_RS05280
uniprot id: Q8EHS2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

211586:SO RS22115
gene id: 211586:SO_RS22115
uniprot id: Q8E8B2
names: Function
names: Similarity
messages: Belongs to the ParB family.
messages: Involved in chromosome partition. Localize to both poles of the predivisional cell following completion of DNA replication. Binds to the DNA origin of replication.

211586:SO RS20325
gene id: 211586:SO_RS20325
uniprot id: Q8E9A8
names: Subunit
messages: Monomer.

211586:SO RS19900
gene id: 211586:SO_RS19900
uniprot id: Q8E9I5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PstS family.
messages: Involved in the system for phosphate transport across the cytoplasmic membrane.
messages: Periplasm
messages: Secreted

211586:SO RS10895
gene id: 211586:SO_RS10895
uniprot id: Q8EEK6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

211586:SO RS12815
gene id: 211586:SO_RS12815
uniprot id: Q8EDI2
names: Similarity
messages: Belongs to the asparagine synthetase family.

211586:SO RS17945
gene id: 211586:SO_RS17945
uniprot id: Q8EAP2
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.
messages: Homotetramer.

211586:SO RS17305
gene id: 211586:SO_RS17305
uniprot id: Q8CMJ3
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

211586:SO RS11365
gene id: 211586:SO_RS11365
uniprot id: Q8EEB0
names: Activity Regulation
names: Cofactor
names: Disruption Phenotype
names: Function
names: Miscellaneous
names: Similarity
messages: A double kdnA/kdnB deletion mutant shows increased sensitivity to polymyxin B and bile salts.
messages: Belongs to the iron-containing alcohol dehydrogenase family.
messages: Catalyzes the first step of the biosynthesis of Kdo8N (8-amino-3,8-dideoxy-D-manno-octulosonate) from Kdo (3-deoxy-D-manno-octulosonate).
messages: Inhibited by EDTA.
messages: Kdo8N is found in lipopolysaccharides of members of the Shewanella genus.
messages: Shows highest activity with Mn(2+) and Fe(2+).

211586:SO RS01605
gene id: 211586:SO_RS01605
uniprot id: Q8EJX0
names: Subcellular Location Annotation
messages: Membrane

211586:SO RS21395
gene id: 211586:SO_RS21395
uniprot id: Q8E8Q5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 2 family.
messages: Binds a copper A center.
messages: Cell membrane
messages: Membrane
messages: Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B).

211586:SO RS04110
gene id: 211586:SO_RS04110
uniprot id: Q8EIG4
names: Similarity
messages: Belongs to the SfsA family.

211586:SO RS07585
gene id: 211586:SO_RS07585
uniprot id: Q8EGG2
names: Function
names: Similarity
messages: Belongs to the LpxB family.
messages: Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

211586:SO RS15460
gene id: 211586:SO_RS15460
uniprot id: Q8EC29
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity.

211586:SO RS05075
gene id: 211586:SO_RS05075
uniprot id: Q8EHW5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RlmG family.
messages: Cytoplasm
messages: Specifically methylates the guanine in position 1835 (m2G1835) of 23S rRNA.

211586:SO RS19000
gene id: 211586:SO_RS19000
uniprot id: Q8EA11
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

211586:SO RS14260
gene id: 211586:SO_RS14260
uniprot id: Q8ECR0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Catalyzes the last two steps in the biosynthesis of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the DAO family.
messages: In the N-terminal section; belongs to the methyltransferase superfamily. tRNA (mnm(5)s(2)U34)-methyltransferase family.

211586:SO RS10835
gene id: 211586:SO_RS10835
uniprot id: Q8EEL8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CcoP / FixP family.
messages: Binds 2 heme C groups per subunit.
messages: C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex.
messages: Cell inner membrane
messages: Component of the cbb3-type cytochrome c oxidase.

211586:SO RS02695
gene id: 211586:SO_RS02695
uniprot id: Q8EJA2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

211586:SO RS16225
gene id: 211586:SO_RS16225
uniprot id: Q8EBN9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

211586:SO RS10660
gene id: 211586:SO_RS10660
uniprot id: Q8EEQ2
names: Function
messages: Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP.

211586:SO RS01195
gene id: 211586:SO_RS01195
uniprot id: Q8EK51
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

211586:SO RS05680
gene id: 211586:SO_RS05680
uniprot id: Q8EHK0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PNP/UDP phosphorylase family.
messages: Catalyzes the reversible phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.
messages: Homohexamer; trimer of homodimers.

211586:SO RS04375
gene id: 211586:SO_RS04375
uniprot id: Q8EIB1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Monomer.

211586:SO RS00755
gene id: 211586:SO_RS00755
uniprot id: Q8EKD1
names: Similarity
messages: Belongs to the HSP15 family.

211586:SO RS06260
gene id: 211586:SO_RS06260
uniprot id: Q8EH80
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell inner membrane
messages: Cytoplasm
messages: Monomer.

211586:SO RS08695
gene id: 211586:SO_RS08695
uniprot id: Q8EFT5
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

211586:SO RS13420
gene id: 211586:SO_RS13420
uniprot id: Q8ED71
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the pyridoxamine 5'-phosphate oxidase family.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
messages: Homodimer.

211586:SO RS11105
gene id: 211586:SO_RS11105
uniprot id: Q8EEG1
names: Similarity
messages: Belongs to the asparaginase 1 family.

211586:SO RS22290
gene id: 211586:SO_RS22290
uniprot id: Q8CMJ3
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

211586:SO RS19875
gene id: 211586:SO_RS19875
uniprot id: Q8E9J0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

211586:SO RS14295
gene id: 211586:SO_RS14295
uniprot id: P59236
names: Similarity
messages: Belongs to the UPF0115 family.

211586:SO RS01335
gene id: 211586:SO_RS01335
uniprot id: Q8EK29
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm
messages: Lacks the conserved threonine residue in position 50, which is part of the carbamoylphosphate binding site; it is replaced by a leucine residue.
messages: Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline.

211586:SO RS12975
gene id: 211586:SO_RS12975
uniprot id: Q8EDF2
names: Similarity
messages: Belongs to the UPF0434 family.

211586:SO RS08325
gene id: 211586:SO_RS08325
uniprot id: Q8EG03
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0283 family.
messages: Cell inner membrane

211586:SO RS15395
gene id: 211586:SO_RS15395
uniprot id: Q8EC44
names: Subcellular Location Annotation
messages: Periplasm

211586:SO RS05450
gene id: 211586:SO_RS05450
uniprot id: Q8EHN8
names: Similarity
messages: Belongs to the PhoH family.

211586:SO RS07090
gene id: 211586:SO_RS07090
uniprot id: Q8EGR8
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

211586:SO RS04000
gene id: 211586:SO_RS04000
uniprot id: Q8EII6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP H family.
messages: Cell inner membrane
messages: Membrane

211586:SO RS05185
gene id: 211586:SO_RS05185
uniprot id: Q8EHU1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

211586:SO RS16060
gene id: 211586:SO_RS16060
uniprot id: Q8EBR4
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruD family.
messages: Responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs.

211586:SO RS01395
gene id: 211586:SO_RS01395
uniprot id: Q8EK17
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

211586:SO RS01240
gene id: 211586:SO_RS01240
uniprot id: Q8EK44
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmE/CycJ family.
messages: Cell inner membrane
messages: Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH (By similarity).

211586:SO RS16425
gene id: 211586:SO_RS16425
uniprot id: Q8EBK0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

211586:SO RS02870
gene id: 211586:SO_RS02870
uniprot id: Q8EJ69
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Hfq family.
messages: Homohexamer.
messages: RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs.

211586:SO RS03935
gene id: 211586:SO_RS03935
uniprot id: Q8EIK0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

211586:SO RS21960
gene id: 211586:SO_RS21960
uniprot id: Q8E8E1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. MoaA family.
messages: Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.
messages: Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
messages: Monomer and homodimer.

211586:SO RS01330
gene id: 211586:SO_RS01330
uniprot id: P59301
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm

211586:SO RS07915
gene id: 211586:SO_RS07915
uniprot id: Q8EG87
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Membrane

211586:SO RS11430
gene id: 211586:SO_RS11430
uniprot id: Q8EE96
names: Similarity
messages: Belongs to the pyruvate kinase family.

211586:SO RS10565
gene id: 211586:SO_RS10565
uniprot id: Q8EER5
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

211586:SO RS07640
gene id: 211586:SO_RS07640
uniprot id: Q8EGE9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inositol monophosphatase superfamily. CysQ family.
messages: Cell inner membrane
messages: Converts adenosine-3',5'-bisphosphate (PAP) to AMP.

211586:SO RS19780
gene id: 211586:SO_RS19780
uniprot id: Q8E9K6
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

211586:SO RS21705
gene id: 211586:SO_RS21705
uniprot id: Q8E8J4
names: Function
names: Similarity
messages: Belongs to the peptidase C56 family.
messages: Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate.

211586:SO RS08525
gene id: 211586:SO_RS08525
uniprot id: Q8EFW4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RlmKL family.
messages: Cytoplasm
messages: Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA.

211586:SO RS18515
gene id: 211586:SO_RS18515
uniprot id: Q8EAC7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome c-552 family.
messages: Binds 1 Ca(2+) ion per monomer.
messages: Binds 5 heme c groups covalently per monomer.
messages: Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process (PubMed:22382353). Has very low activity toward hydroxylamine (PubMed:22382353). Has even lower activity toward sulfite. Sulfite reductase activity is maximal at neutral pH (By similarity).
messages: Homodimer.
messages: Periplasm

211586:SO RS08585
gene id: 211586:SO_RS08585
uniprot id: Q8EFV3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

211586:SO RS17045
gene id: 211586:SO_RS17045
uniprot id: Q8EB80
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

211586:SO RS15160
gene id: 211586:SO_RS15160
uniprot id: Q8EC95
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

211586:SO RS19820
gene id: 211586:SO_RS19820
uniprot id: Q8E9K1
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell inner membrane

211586:SO RS17195
gene id: 211586:SO_RS17195
uniprot id: Q8EB48
names: Function
messages: May be involved in the biogenesis of curli organelles.

211586:SO RS10215
gene id: 211586:SO_RS10215
uniprot id: Q8EEY7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I fumarase family.
messages: Catalyzes the reversible hydration of fumarate to (S)-malate.
messages: Homodimer.

211586:SO RS08200
gene id: 211586:SO_RS08200
uniprot id: Q8EG24
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LpxH family.
messages: Binds 2 Mn(2+) ions per subunit in a binuclear metal center.
messages: Cell inner membrane
messages: Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

211586:SO RS08485
gene id: 211586:SO_RS08485
uniprot id: Q8EFW9
names: Activity Regulation
names: Disruption Phenotype
names: Function
names: Induction
names: Subunit
messages: Deletion of the gene leads to a dramatically reduced growth at low temperature.
messages: Interaction with AtcJ stabilizes AtcC.
messages: Interacts with the C-terminal extension of AtcJ (PubMed:31482142). Also interacts with AtcB, but not with AtcA (PubMed:31482142).
messages: Involved in cold adaptation.
messages: Part of the atcJABC operon (PubMed:31482142). The operon is constitutively expressed, and expression shows only a very slight increase at low temperature (PubMed:31482142).

211586:SO RS19850
gene id: 211586:SO_RS19850
uniprot id: Q8E9J5
names: Subcellular Location Annotation
messages: Membrane

211586:SO RS11460
gene id: 211586:SO_RS11460
uniprot id: P59192
names: Similarity
messages: Belongs to the UPF0225 family.

211586:SO RS08785
gene id: 211586:SO_RS08785
uniprot id: Q8EFR7
names: Similarity
messages: Belongs to the YkuD family.

211586:SO RS07580
gene id: 211586:SO_RS07580
uniprot id: Q8EGG3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxA subfamily.
messages: Cytoplasm
messages: Homotrimer.
messages: Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

211586:SO RS06270
gene id: 211586:SO_RS06270
uniprot id: Q8EH78
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PNP synthase family.
messages: Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.
messages: Cytoplasm
messages: Homooctamer; tetramer of dimers.

211586:SO RS10010
gene id: 211586:SO_RS10010
uniprot id: Q8EF24
names: Cofactor
names: PTM
names: Subcellular Location Annotation
messages: Binds 2 heme groups per subunit.
messages: Binds 2 heme groups.
messages: Periplasm

211586:SO RS12630
gene id: 211586:SO_RS12630
uniprot id: Q8EDK8
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily.
messages: Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl-L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway.

211586:SO RS15940
gene id: 211586:SO_RS15940
uniprot id: Q8EBT0
names: Similarity
messages: Belongs to the TrpR family.

211586:SO RS02000
gene id: 211586:SO_RS02000
uniprot id: Q8EJP8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A24 family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Plays an essential role in type IV pili and type II pseudopili formation by proteolytically removing the leader sequence from substrate proteins and subsequently monomethylating the alpha-amino group of the newly exposed N-terminal phenylalanine.

211586:SO RS05455
gene id: 211586:SO_RS05455
uniprot id: Q8CX45
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methylthiotransferase family. MiaB subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
messages: Cytoplasm
messages: Monomer.

211586:SO RS11510
gene id: 211586:SO_RS11510
uniprot id: Q8EE83
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

211586:SO RS07535
gene id: 211586:SO_RS07535
uniprot id: Q8EGH2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

211586:SO RS19750
gene id: 211586:SO_RS19750
uniprot id: Q8CME4
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

211586:SO RS16715
gene id: 211586:SO_RS16715
uniprot id: Q8EBE6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent (By similarity).
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE. Acts before DnaK, in the processing of protein aggregates. Protein binding stimulates the ATPase activity; ATP hydrolysis unfolds the denatured protein aggregates, which probably helps expose new hydrophobic binding sites on the surface of ClpB-bound aggregates, contributing to the solubilization and refolding of denatured protein aggregates by DnaK (By similarity).
messages: The Clp repeat (R) domain probably functions as a substrate-discriminating domain, recruiting aggregated proteins to the ClpB hexamer and/or stabilizing bound proteins. The NBD2 domain is responsible for oligomerization, whereas the NBD1 domain stabilizes the hexamer probably in an ATP-dependent manner. The movement of the coiled-coil domain is essential for ClpB ability to rescue proteins from an aggregated state, probably by pulling apart large aggregated proteins, which are bound between the coiled-coils motifs of adjacent ClpB subunits in the functional hexamer (By similarity).

211586:SO RS03495
gene id: 211586:SO_RS03495
uniprot id: Q8EIU3
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the gamma-glutamyltransferase family.
messages: Cleaved by autocatalysis into a large and a small subunit.
messages: This enzyme consists of two polypeptide chains, which are synthesized in precursor form from a single polypeptide.

211586:SO RS18235
gene id: 211586:SO_RS18235
uniprot id: Q8EAI5
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins.

211586:SO RS03000
gene id: 211586:SO_RS03000
uniprot id: Q8EJ40
names: Function
names: Similarity
messages: Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits).
messages: In the C-terminal section; belongs to the transpeptidase family.
messages: In the N-terminal section; belongs to the glycosyltransferase 51 family.

211586:SO RS02730
gene id: 211586:SO_RS02730
uniprot id: Q8EJ93
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SNF2/RAD54 helicase family. RapA subfamily.
messages: Interacts with the RNAP. Has a higher affinity for the core RNAP than for the holoenzyme. Its ATPase activity is stimulated by binding to RNAP.
messages: Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair.

211586:SO RS01160
gene id: 211586:SO_RS01160
uniprot id: Q8EK57
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

211586:SO RS17975
gene id: 211586:SO_RS17975
uniprot id: Q8EAN7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueG family.
messages: Binds 2 [4Fe-4S] clusters per monomer.
messages: Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr).
messages: Cytoplasm
messages: Monomer.

211586:SO RS12640
gene id: 211586:SO_RS12640
uniprot id: Q8EDK6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. Biotin synthase family.
messages: Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
messages: Homodimer.

211586:SO RS13005
gene id: 211586:SO_RS13005
uniprot id: Q8EDE6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PsiE family.
messages: Cell inner membrane
messages: Membrane

211586:SO RS17645
gene id: 211586:SO_RS17645
uniprot id: Q8EAV2
names: Function
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.
messages: Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine.

211586:SO RS04365
gene id: 211586:SO_RS04365
uniprot id: Q8EIB3
names: Similarity
messages: Belongs to the transketolase family.

211586:SO RS06985
gene id: 211586:SO_RS06985
uniprot id: Q8EGT6
names: Subcellular Location Annotation
messages: Membrane

211586:SO RS05585
gene id: 211586:SO_RS05585
uniprot id: Q8EHL8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

211586:SO RS01145
gene id: 211586:SO_RS01145
uniprot id: Q8EK60
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

211586:SO RS01040
gene id: 211586:SO_RS01040
uniprot id: Q8EK79
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

211586:SO RS00115
gene id: 211586:SO_RS00115
uniprot id: Q8EKR7
names: Similarity
messages: Belongs to the IMPACT family.

211586:SO RS16010
gene id: 211586:SO_RS16010
uniprot id: Q8EBS3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Mediates global changes in gene expression, shifting from rapid growth to stress survival by linking envelope stress, the stringent response and the catabolite repression systems. Usually binds in the 5'-UTR; binding at or near the Shine-Dalgarno sequence prevents ribosome-binding, repressing translation, binding elsewhere in the 5'-UTR can activate translation and/or stabilize the mRNA. Its function is antagonized by small RNA(s).
messages: Belongs to the CsrA/RsmA family.
messages: Cytoplasm
messages: Homodimer; the beta-strands of each monomer intercalate to form a hydrophobic core, while the alpha-helices form wings that extend away from the core.

211586:SO RS02020
gene id: 211586:SO_RS02020
uniprot id: K4PSN6
names: Function
names: Similarity
messages: Belongs to the NadC/ModD family.
messages: Involved in the catabolism of quinolinic acid (QA).

211586:SO RS04850
gene id: 211586:SO_RS04850
uniprot id: Q8EI11
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Membrane

211586:SO RS04750
gene id: 211586:SO_RS04750
uniprot id: Q8EI33
names: Function
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.

211586:SO RS11565
gene id: 211586:SO_RS11565
uniprot id: Q8EE77
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RnfG family.
messages: Cell inner membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

211586:SO RS02900
gene id: 211586:SO_RS02900
uniprot id: Q8EJ62
names: Cofactor
messages: Binds 1 heme c group covalently per subunit.

211586:SO RS10420
gene id: 211586:SO_RS10420
uniprot id: Q8EEU3
names: Cofactor
names: Similarity
messages: Belongs to the RimK family.
messages: Binds 2 magnesium or manganese ions per subunit.

211586:SO RS15860
gene id: 211586:SO_RS15860
uniprot id: Q8EBU8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

211586:SO RS15625
gene id: 211586:SO_RS15625
uniprot id: Q8EBZ4
names: Similarity
messages: Belongs to the GSP E family.

211586:SO RS01045
gene id: 211586:SO_RS01045
uniprot id: Q8EK78
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

211586:SO RS13345
gene id: 211586:SO_RS13345
uniprot id: Q8ED85
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

211586:SO RS21450
gene id: 211586:SO_RS21450
uniprot id: Q8E8P4
names: Subcellular Location Annotation
messages: Membrane

211586:SO RS21675
gene id: 211586:SO_RS21675
uniprot id: Q8E8K2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LemA family.
messages: Membrane

211586:SO RS00150
gene id: 211586:SO_RS00150
uniprot id: Q8EKR0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Cytoplasm
messages: Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.

211586:SO RS06515
gene id: 211586:SO_RS06515
uniprot id: Q8EH28
names: Similarity
messages: Belongs to the UPF0597 family.

211586:SO RS06565
gene id: 211586:SO_RS06565
uniprot id: Q8EH18
names: Subcellular Location Annotation
messages: Periplasm

211586:SO RS18315
gene id: 211586:SO_RS18315
uniprot id: Q8EAG7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.
messages: Belongs to the RNR ribonuclease family. RNase R subfamily.
messages: Cytoplasm

211586:SO RS08185
gene id: 211586:SO_RS08185
uniprot id: Q8EG26
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

211586:SO RS06185
gene id: 211586:SO_RS06185
uniprot id: Q8EH95
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell inner membrane

211586:SO RS20470
gene id: 211586:SO_RS20470
uniprot id: Q8E978
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

211586:SO RS22620
gene id: 211586:SO_RS22620
uniprot id: Q8E837
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

211586:SO RS15040
gene id: 211586:SO_RS15040
uniprot id: Q8ECB9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliJ family.
messages: Cell membrane
messages: Membrane

211586:SO RS03850
gene id: 211586:SO_RS03850
uniprot id: Q8EIM0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 independent methionine synthase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine resulting in methionine formation.

211586:SO RS08385
gene id: 211586:SO_RS08385
uniprot id: Q8EFZ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

211586:SO RS18055
gene id: 211586:SO_RS18055
uniprot id: Q8EAM2
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

211586:SO RS06445
gene id: 211586:SO_RS06445
uniprot id: Q8EH42
names: Similarity
messages: Belongs to the peptidase M24B family.

211586:SO RS18280
gene id: 211586:SO_RS18280
uniprot id: Q8EAH5
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

211586:SO RS07550
gene id: 211586:SO_RS07550
uniprot id: Q8EGG9
names: Function
names: Similarity
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).

211586:SO RS10890
gene id: 211586:SO_RS10890
uniprot id: Q8EEK7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

211586:SO RS14070
gene id: 211586:SO_RS14070
uniprot id: P59365
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YciB family.
messages: Cell inner membrane
messages: Plays a role in cell envelope biogenesis, maintenance of cell envelope integrity and membrane homeostasis.

211586:SO RS04620
gene id: 211586:SO_RS04620
uniprot id: Q8EI62
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

211586:SO RS01100
gene id: 211586:SO_RS01100
uniprot id: Q8EK68
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: Methylated by PrmB.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

211586:SO RS02700
gene id: 211586:SO_RS02700
uniprot id: Q8EJA1
names: Domain
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.
messages: The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate.

211586:SO RS02595
gene id: 211586:SO_RS02595
uniprot id: Q8EJC1
names: Cofactor
names: Similarity
messages: Belongs to the RimK family.
messages: Binds 2 magnesium or manganese ions per subunit.

211586:SO RS07590
gene id: 211586:SO_RS07590
uniprot id: Q8EGG1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

211586:SO RS13030
gene id: 211586:SO_RS13030
uniprot id: Q8CMJ3
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

211586:SO RS02720
gene id: 211586:SO_RS02720
uniprot id: Q8EJ96
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

211586:SO RS21435
gene id: 211586:SO_RS21435
uniprot id: Q8E8P7
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
messages: Carbon 2 of the heme B porphyrin ring is defined according to the Fischer nomenclature.
messages: Cell inner membrane
messages: Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.

211586:SO RS16990
gene id: 211586:SO_RS16990
uniprot id: Q8EB94
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PdxA family.
messages: Binds 1 divalent metal cation per subunit. Can use ions such as Zn(2+), Mg(2+) or Co(2+).
messages: Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L-threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP).
messages: Cytoplasm
messages: Homodimer.
messages: The active site is located at the dimer interface.

211586:SO RS07515
gene id: 211586:SO_RS07515
uniprot id: Q8EGH7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

211586:SO RS00460
gene id: 211586:SO_RS00460
uniprot id: Q8EKK0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PNP/UDP phosphorylase family.
messages: Catalyzes the reversible phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.
messages: Homohexamer; trimer of homodimers.

211586:SO RS21695
gene id: 211586:SO_RS21695
uniprot id: Q8E8J7
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

211586:SO RS10375
gene id: 211586:SO_RS10375
uniprot id: Q8EEV2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.
messages: Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA.
messages: Cytoplasm
messages: Homodimer.

211586:SO RS11930
gene id: 211586:SO_RS11930
uniprot id: Q8EE00
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily.
messages: Cytoplasm
messages: Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity.

211586:SO RS19340
gene id: 211586:SO_RS19340
uniprot id: Q8E9T9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Binds 1 Mg(2+) ion per monomer.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

211586:SO RS01935
gene id: 211586:SO_RS01935
uniprot id: Q8EJR0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

211586:SO RS17690
gene id: 211586:SO_RS17690
uniprot id: K4PSW3
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

211586:SO RS22915
gene id: 211586:SO_RS22915
uniprot id: Q8CM48
names: Similarity
messages: Belongs to the transposase 7 family.

211586:SO RS06360
gene id: 211586:SO_RS06360
uniprot id: Q8EH61
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptF/LptG family.
messages: Cell inner membrane
messages: Component of the lipopolysaccharide transport and assembly complex. The LptBFG transporter is composed of two ATP-binding proteins (LptB) and two transmembrane proteins (LptF and LptG).
messages: Membrane
messages: Part of the ABC transporter complex LptBFG involved in the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane.

211586:SO RS12590
gene id: 211586:SO_RS12590
uniprot id: Q8EDL6
names: Subcellular Location Annotation
messages: Periplasm

211586:SO RS08365
gene id: 211586:SO_RS08365
uniprot id: Q8EFZ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

211586:SO RS05295
gene id: 211586:SO_RS05295
uniprot id: Q8EHR8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RlmI family.
messages: Cytoplasm
messages: Specifically methylates the cytosine at position 1962 (m5C1962) of 23S rRNA.

211586:SO RS00865
gene id: 211586:SO_RS00865
uniprot id: Q8EKA8
names: Similarity
messages: Belongs to the peptidase S8 family.

211586:SO RS21170
gene id: 211586:SO_RS21170
uniprot id: Q8E8U9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

211586:SO RS16575
gene id: 211586:SO_RS16575
uniprot id: Q8EBH1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm

211586:SO RS05580
gene id: 211586:SO_RS05580
uniprot id: Q8EHL9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

211586:SO RS06295
gene id: 211586:SO_RS06295
uniprot id: Q8EH73
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. SRP is a ribonucleoprotein composed of Ffh and a 4.5S RNA molecule.

211586:SO RS11100
gene id: 211586:SO_RS11100
uniprot id: Q8EEG2
names: Similarity
messages: Belongs to the peptidase S49 family.

211586:SO RS21565
gene id: 211586:SO_RS21565
uniprot id: Q8E8M1
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

211586:SO RS08315
gene id: 211586:SO_RS08315
uniprot id: Q8EG05
names: Subcellular Location Annotation
messages: Membrane

211586:SO RS07665
gene id: 211586:SO_RS07665
uniprot id: Q8EGE3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

211586:SO RS08180
gene id: 211586:SO_RS08180
uniprot id: Q8EG28
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.
messages: Cell inner membrane
messages: Membrane
messages: Probable transporter of a GTP-driven Fe(2+) uptake system.

211586:SO RS16235
gene id: 211586:SO_RS16235
uniprot id: Q8EBN7
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.
messages: Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).
messages: The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.
messages: The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1.

211586:SO RS14915
gene id: 211586:SO_RS14915
uniprot id: Q8ECE6
names: Similarity
messages: Belongs to the MlaA family.

211586:SO RS20425
gene id: 211586:SO_RS20425
uniprot id: Q8E988
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

211586:SO RS12665
gene id: 211586:SO_RS12665
uniprot id: Q8EDK1
names: Similarity
names: Subunit
messages: Belongs to the glutaredoxin family.
messages: Monomer.

211586:SO RS18465
gene id: 211586:SO_RS18465
uniprot id: Q8EAE0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

211586:SO RS19485
gene id: 211586:SO_RS19485
uniprot id: Q8E9Q8
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Homooctamer.

211586:SO RS10905
gene id: 211586:SO_RS10905
uniprot id: Q8EEK4
names: Similarity
messages: Belongs to the DsrF/TusC family.

211586:SO RS05925
gene id: 211586:SO_RS05925
uniprot id: Q8EHE6
names: Subcellular Location Annotation
messages: Membrane

211586:SO RS05035
gene id: 211586:SO_RS05035
uniprot id: Q8EHX2
names: Subcellular Location Annotation
messages: Membrane

211586:SO RS16755
gene id: 211586:SO_RS16755
uniprot id: K4PSJ9
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

211586:SO RS17885
gene id: 211586:SO_RS17885
uniprot id: Q8EAQ6
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

211586:SO RS07495
gene id: 211586:SO_RS07495
uniprot id: Q8EGI1
names: Subcellular Location Annotation
messages: Membrane

211586:SO RS12925
gene id: 211586:SO_RS12925
uniprot id: Q8EDG2
names: Cofactor
messages: Binds 2 Mg(2+) ions per monomer.

211586:SO RS08950
gene id: 211586:SO_RS08950
uniprot id: Q8EFN2
names: Cofactor
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: 2 residues (Tyr-54 and Arg-57) present in a large hydrophobic pocket are probably involved in substrate specificity. They are important for desuccinylation activity, but dispensable for deacetylation activity.
messages: Belongs to the sirtuin family. Class III subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form.
messages: This protein might be subject to alternative promoter usage and might also encode a protein with a 7 or 13 residue-longer N-terminus.

211586:SO RS04515
gene id: 211586:SO_RS04515
uniprot id: Q8EI83
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Cell inner membrane
messages: Homoheptamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mechanosensitive channel that participates in the regulation of osmotic pressure changes within the cell, opening in response to stretch forces in the membrane lipid bilayer, without the need for other proteins. Contributes to normal resistance to hypoosmotic shock. Forms an ion channel of 1.0 nanosiemens conductance with a slight preference for anions.

211586:SO RS12740
gene id: 211586:SO_RS12740
uniprot id: Q8EDJ5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ExbB/TolQ family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

211586:SO RS04065
gene id: 211586:SO_RS04065
uniprot id: Q8EIH3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CsgA/CsgB family.
messages: Fimbrium

211586:SO RS14480
gene id: 211586:SO_RS14480
uniprot id: Q8ECL7
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Belongs to the Gfo/Idh/MocA family. Glycosyl hydrolase 109 subfamily.
messages: Binds 1 NAD(+) per subunit. The NAD(+) cannot dissociate.
messages: Glycosidase that has specific alpha-N-acetylgalactosaminidase activity.
messages: Predicted to be exported by the Tat system. The position of the signal peptide cleavage has not been experimentally proven.

211586:SO RS16965
gene id: 211586:SO_RS16965
uniprot id: Q8EB99
names: Domain
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cell inner membrane
messages: Homodimer.
messages: Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB/RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host.
messages: The transmembrane domain is a dimerization domain.

211586:SO RS00530
gene id: 211586:SO_RS00530
uniprot id: Q8EKI5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsuA/YedE (TC 9.B.102) family.
messages: Cell inner membrane
messages: Membrane

211586:SO RS10405
gene id: 211586:SO_RS10405
uniprot id: Q8EEU6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HscB family.
messages: Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA.
messages: Interacts with HscA and stimulates its ATPase activity.

211586:SO RS07790
gene id: 211586:SO_RS07790
uniprot id: Q8EGB6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

211586:SO RS18830
gene id: 211586:SO_RS18830
uniprot id: Q8EA55
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

211586:SO RS09215
gene id: 211586:SO_RS09215
uniprot id: Q8EFH5
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M1 family.
messages: Binds 1 zinc ion per subunit.

211586:SO RS11910
gene id: 211586:SO_RS11910
uniprot id: Q8EE03
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Homooctamer.

211586:SO RS03900
gene id: 211586:SO_RS03900
uniprot id: Q8EIK9
names: Cofactor
names: Similarity
messages: Belongs to the alkaline phosphatase family.
messages: Binds 1 Mg(2+) ion.
messages: Binds 2 Zn(2+) ions.

211586:SO RS01375
gene id: 211586:SO_RS01375
uniprot id: Q8EK21
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial secretin family. PilQ subfamily.
messages: Cell outer membrane
messages: Membrane

211586:SO RS15905
gene id: 211586:SO_RS15905
uniprot id: Q8EBT8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S41B family.
messages: Cytoplasm
messages: Degrades oligopeptides.

211586:SO RS05570
gene id: 211586:SO_RS05570
uniprot id: Q8EHM1
names: Function
names: Similarity
messages: Belongs to the DHPS family.
messages: Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives.

211586:SO RS10590
gene id: 211586:SO_RS10590
uniprot id: Q8EER1
names: Function
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.
messages: DNA-dependent ATPase that plays important roles in cellular responses to stalled DNA replication processes.

211586:SO RS10595
gene id: 211586:SO_RS10595
uniprot id: Q8EER0
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fluoride channel Fluc/FEX (TC 1.A.43) family.
messages: Cell inner membrane
messages: Fluoride-specific ion channel. Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Na(+) is not transported, but it plays an essential structural role and its presence is essential for fluoride channel function.

211586:SO RS17715
gene id: 211586:SO_RS17715
uniprot id: Q8EAT9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm
messages: Purine salvage pathway enzyme which catalyzes the transfer of the ribosyl-5-phosphate group from 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to the N9 position of hypoxanthine to yield IMP (inosine 5'-monophosphate). To a lesser extent, can also act on guanine leading to GMP, but shows a highly less efficient activity with xanthine.

211586:SO RS16435
gene id: 211586:SO_RS16435
uniprot id: Q8EBJ7
names: Similarity
messages: Belongs to the NADH dehydrogenase family.

211586:SO RS04475
gene id: 211586:SO_RS04475
uniprot id: Q8EI93
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbC subfamily.
messages: Periplasm
messages: Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process.

211586:SO RS14375
gene id: 211586:SO_RS14375
uniprot id: Q8ECN7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OmpP1/FadL family.
messages: Cell outer membrane
messages: Membrane

211586:SO RS18210
gene id: 211586:SO_RS18210
uniprot id: Q8EAJ0
names: Function
names: Similarity
messages: Belongs to the Dus family. DusA subfamily.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U20 and U20a in tRNAs.

211586:SO RS15150
gene id: 211586:SO_RS15150
uniprot id: Q8EC97
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.

211586:SO RS00950
gene id: 211586:SO_RS00950
uniprot id: Q8CX51
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. TrmA subfamily.
messages: Dual-specificity methyltransferase that catalyzes the formation of 5-methyluridine at position 54 (m5U54) in all tRNAs, and that of position 341 (m5U341) in tmRNA (transfer-mRNA).

211586:SO RS17445
gene id: 211586:SO_RS17445
uniprot id: Q8EAZ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LpxL/LpxM/LpxP family.
messages: Catalyzes the transfer of an acyl chain from an acyl-[acyl-carrier-protein] (ACP) to a Kdo(2)-lipid IV(A) to form a Kdo(2)-(acyl)-lipid IV(A).
messages: Cell inner membrane

211586:SO RS01120
gene id: 211586:SO_RS01120
uniprot id: Q8EK64
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

211586:SO RS22905
gene id: 211586:SO_RS22905
uniprot id: Q8E7Z8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

211586:SO RS08130
gene id: 211586:SO_RS08130
uniprot id: Q8EG37
names: Similarity
messages: Belongs to the CdaR family.

211586:SO RS03345
gene id: 211586:SO_RS03345
uniprot id: Q8EIX3
names: Disruption Phenotype
names: Function
names: Induction
names: Similarity
names: Subunit
messages: 50% decrease in biofilm.
messages: Belongs to the HipA Ser/Thr kinase family.
messages: Expressed in late-exponential phase; part of the hipBA operon.
messages: Monomer. Forms a HipA(2)HipB(2)-DNA complex with cognate antitoxin HipB; has higher affinity for the latter when HipB is prebound to DNA and HipA is phosphorylated. Binds DNA in the ternary complex.
messages: Toxic component of a type II toxin-antitoxin (TA) system; overexpression in wild-type temporarily inhibits cell growth, overexpression in a hipAB deletion leads to acute growth inhibition. The toxic effect of HipA is neutralized by its cognate antitoxin HipB. In the ternary phosphoserine-HipA-HipB-DNA complex the DNA is bent about 125 degrees; all HipA in the crystallized ternary complex is phosphorylated. In E.coli phosphorylation of HipA is thought to release HipB from the HipA-HipB-DNA complex, suggesting the complex functions differently in the 2 bacteria (PubMed:25056321). Phosphorylates Glu-tRNA-ligase (GltX, on 'Ser-239') in vivo, with HipB probably acts as a corepressor for transcription of the hipBA promoter (By similarity).

211586:SO RS16320
gene id: 211586:SO_RS16320
uniprot id: Q8EBL9
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

211586:SO RS06090
gene id: 211586:SO_RS06090
uniprot id: Q8EHB5
names: Function
names: Similarity
messages: Belongs to the anhydro-N-acetylmuramic acid kinase family.
messages: Catalyzes the specific phosphorylation of 1,6-anhydro-N-acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling.

211586:SO RS03020
gene id: 211586:SO_RS03020
uniprot id: Q8EJ34
names: Subcellular Location Annotation
messages: Secreted

211586:SO RS05965
gene id: 211586:SO_RS05965
uniprot id: Q8EHD9
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

211586:SO RS21375
gene id: 211586:SO_RS21375
uniprot id: Q8E8R0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid/polyamine transporter 2 family. Mtr/TnaB/TyrP permease subfamily.
messages: Cell inner membrane
messages: Involved in transporting aromatic amino acids across the cytoplasmic membrane.
messages: Membrane

211586:SO RS15325
gene id: 211586:SO_RS15325
uniprot id: Q8EC62
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

211586:SO RS13350
gene id: 211586:SO_RS13350
uniprot id: Q8ED84
names: Similarity
messages: Belongs to the glutaredoxin family. Monothiol subfamily.

211586:SO RS16570
gene id: 211586:SO_RS16570
uniprot id: Q8EBH2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transaldolase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

211586:SO RS10490
gene id: 211586:SO_RS10490
uniprot id: Q8EET2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Membrane

211586:SO RS07070
gene id: 211586:SO_RS07070
uniprot id: Q8EGS2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lactate permease family.
messages: Cell inner membrane
messages: Membrane
messages: Uptake of L-lactate across the membrane. Can also transport D-lactate and glycolate.

211586:SO RS17995
gene id: 211586:SO_RS17995
uniprot id: Q8EAN3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. Molybdate importer (TC 3.A.1.8) family.
messages: Cell inner membrane
messages: Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system.
messages: The complex is composed of two ATP-binding proteins (ModC), two transmembrane proteins (ModB) and a solute-binding protein (ModA).

211586:SO RS19835
gene id: 211586:SO_RS19835
uniprot id: Q8E9J8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TerC family.
messages: Membrane

211586:SO RS06355
gene id: 211586:SO_RS06355
uniprot id: Q8EH62
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M17 family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm
messages: Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity).

211586:SO RS13110
gene id: 211586:SO_RS13110
uniprot id: Q8EDD1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the GTP cyclohydrolase II family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.

211586:SO RS21030
gene id: 211586:SO_RS21030
uniprot id: K4PSM0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

211586:SO RS02085
gene id: 211586:SO_RS02085
uniprot id: Q8EJN0
names: Similarity
messages: Belongs to the Rsd/AlgQ family.

211586:SO RS19440
gene id: 211586:SO_RS19440
uniprot id: Q8E9R7
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2).

211586:SO RS07530
gene id: 211586:SO_RS07530
uniprot id: Q8EGH3
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by GTP. Inhibited by UTP.
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.

211586:SO RS23420
gene id: 211586:SO_RS23420
uniprot id: Q8EC42
names: Similarity
messages: Belongs to the peptidase S8 family.

211586:SO RS11795
gene id: 211586:SO_RS11795
uniprot id: Q8EE29
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

211586:SO RS06315
gene id: 211586:SO_RS06315
uniprot id: Q8EH70
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

211586:SO RS09675
gene id: 211586:SO_RS09675
uniprot id: Q8EF83
names: Cofactor
names: Similarity
messages: Belongs to the ApbE family.
messages: Magnesium. Can also use manganese.

211586:SO RS01205
gene id: 211586:SO_RS01205
uniprot id: Q8EK49
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

211586:SO RS19625
gene id: 211586:SO_RS19625
uniprot id: Q8E9N6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OmpP1/FadL family.
messages: Cell outer membrane
messages: Membrane

211586:SO RS15435
gene id: 211586:SO_RS15435
uniprot id: Q8EC34
names: Similarity
messages: Belongs to the YfgM family.

211586:SO RS20045
gene id: 211586:SO_RS20045
uniprot id: Q8E9G4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
messages: Cell inner membrane

211586:SO RS08070
gene id: 211586:SO_RS08070
uniprot id: Q8EG49
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AzlC family.
messages: Membrane

211586:SO RS09610
gene id: 211586:SO_RS09610
uniprot id: Q8EF95
names: Similarity
messages: Belongs to the HypE family.

211586:SO RS14755
gene id: 211586:SO_RS14755
uniprot id: Q8ECH6
names: Disruption Phenotype
names: Function
names: Induction
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the HepT RNase toxin family.
messages: Expressed during exponential growth, part of the mntA-hepT operon. Under control of MntA.
messages: Forms a complex with cognate antitoxin MntA (PubMed:26112399). Forms a heterooctamer with cognate antitoxin MntA with stoichiometry HepT(6):MntA(2). Two HepT molecules dimerize to form a cleft with 2 Rx4-6H active site motifs in close proximity that probably bind substrate; in the heterooctamer 3 HepT dimers form (PubMed:29555683).
messages: Toxic component of a type VII toxin-antitoxin (TA) system. A bacteriostatic toxin; upon overexpression in situ or in E.coli inhibits cell growth. Cells swell slightly. Neutralized by cognate antitoxin MntA (PubMed:26112399, PubMed:29555683, PubMed:33045733). Cleaves mRNA in a probably endonucleolytic manner; has no activity on rRNA, tRNA, ssDNA or dsDNA. The TA system confers plasmid stability in E.coli (PubMed:29555683). Neutralization is mostly due to tri-AMPylation by MntA (PubMed:33045733).
messages: Tri-AMPylated by cognate antitoxin MntA on Tyr-104; this rotates the residue nearly 180 degrees. Modified protein has much less RNase activity.
messages: When mntA-hepT is deleted, has a sight reduction in swimming motility. No effect when just this gene is deleted.

211586:SO RS15965
gene id: 211586:SO_RS15965
uniprot id: Q8EBS5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

211586:SO RS14045
gene id: 211586:SO_RS14045
uniprot id: Q8ECU3
names: Similarity
messages: Belongs to the lysine N(6)-hydroxylase/L-ornithine N(5)-oxygenase family.

211586:SO RS22545
gene id: 211586:SO_RS22545
uniprot id: Q8E846
names: Similarity
messages: Belongs to the RelE toxin family.

211586:SO RS12860
gene id: 211586:SO_RS12860
uniprot id: Q8EDH2
names: Similarity
messages: Belongs to the fabD family.

211586:SO RS01525
gene id: 211586:SO_RS01525
uniprot id: Q8EJY8
names: Subcellular Location Annotation
messages: Membrane

211586:SO RS04715
gene id: 211586:SO_RS04715
uniprot id: Q8EI40
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Membrane

211586:SO RS10450
gene id: 211586:SO_RS10450
uniprot id: Q8EET8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

211586:SO RS11165
gene id: 211586:SO_RS11165
uniprot id: Q8EEE7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. Cx-SAM synthase family.
messages: Catalyzes the conversion of S-adenosyl-L-methionine (SAM) to carboxy-S-adenosyl-L-methionine (Cx-SAM).
messages: Homodimer.

211586:SO RS19185
gene id: 211586:SO_RS19185
uniprot id: Q8E9X1
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

211586:SO RS05670
gene id: 211586:SO_RS05670
uniprot id: Q8EHK3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.
messages: Homodimer.
messages: The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis.

211586:SO RS16175
gene id: 211586:SO_RS16175
uniprot id: Q8EBP9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

211586:SO RS14325
gene id: 211586:SO_RS14325
uniprot id: Q8ECP6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. Thiolase family.
messages: Catalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed.
messages: Cytoplasm
messages: Heterotetramer of two alpha chains (FadJ) and two beta chains (FadI).

211586:SO RS13255
gene id: 211586:SO_RS13255
uniprot id: Q8EDA5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

211586:SO RS21075
gene id: 211586:SO_RS21075
uniprot id: Q8E8W6
names: Similarity
messages: Belongs to the peptidase S9C family.

211586:SO RS04770
gene id: 211586:SO_RS04770
uniprot id: Q8EI29
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 3 family.
messages: Cell inner membrane
messages: NDH-1 is composed of 13 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

211586:SO RS16200
gene id: 211586:SO_RS16200
uniprot id: Q8EBP4
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

211586:SO RS13470
gene id: 211586:SO_RS13470
uniprot id: Q8ED61
names: Subcellular Location Annotation
messages: Membrane

211586:SO RS04835
gene id: 211586:SO_RS04835
uniprot id: Q8EI15
names: Function
names: Similarity
messages: Belongs to the CobB/CobQ family. CobQ subfamily.
messages: Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation.

211586:SO RS18860
gene id: 211586:SO_RS18860
uniprot id: Q8EA48
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

211586:SO RS17410
gene id: 211586:SO_RS17410
uniprot id: Q8EAZ9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Alpha(8)-beta(8). The alpha component is a flavoprotein, the beta component is a hemoprotein.
messages: Belongs to the NADPH-dependent sulphite reductase flavoprotein subunit CysJ family.
messages: Binds 1 FAD per subunit.
messages: Binds 1 FMN per subunit.
messages: Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH -> FAD -> FMN to the hemoprotein component.
messages: In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
messages: In the N-terminal section; belongs to the flavodoxin family.

211586:SO RS09100
gene id: 211586:SO_RS09100
uniprot id: Q8EFK2
names: Subcellular Location Annotation
messages: Nucleus

211586:SO RS18990
gene id: 211586:SO_RS18990
uniprot id: Q8EA13
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MreD family.
messages: Cell inner membrane
messages: Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins.
messages: Membrane

211586:SO RS05025
gene id: 211586:SO_RS05025
uniprot id: K4PTX7
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

211586:SO RS12725
gene id: 211586:SO_RS12725
uniprot id: Q8EDJ8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TolB family.
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: Periplasm
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

211586:SO RS02845
gene id: 211586:SO_RS02845
uniprot id: Q8EJ73
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Belongs to the NnrE/AIBP family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

211586:SO RS11045
gene id: 211586:SO_RS11045
uniprot id: Q8EEH3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

211586:SO RS18435
gene id: 211586:SO_RS18435
uniprot id: Q8EAE6
names: Function
names: Similarity
messages: Belongs to the ABC transporter superfamily. Outer membrane lipopolysaccharide export (TC 1.B.42) family.
messages: Part of the ABC transporter complex LptBFG involved in the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane. Probably responsible for energy coupling to the transport system.

211586:SO RS14170
gene id: 211586:SO_RS14170
uniprot id: Q8ECS7
names: Similarity
messages: Belongs to the peptidase S33 family.

211586:SO RS22060
gene id: 211586:SO_RS22060
uniprot id: Q8E8C4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

211586:SO RS12185
gene id: 211586:SO_RS12185
uniprot id: Q8EDU9
names: Function
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.
messages: Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate.

211586:SO RS14490
gene id: 211586:SO_RS14490
uniprot id: Q8ECL5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Cell inner membrane
messages: Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system).

211586:SO RS15425
gene id: 211586:SO_RS15425
uniprot id: Q8EC36
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

211586:SO RS17040
gene id: 211586:SO_RS17040
uniprot id: Q8EB81
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

211586:SO RS07295
gene id: 211586:SO_RS07295
uniprot id: Q8EGM4
names: Similarity
messages: Belongs to the GST superfamily.

211586:SO RS01480
gene id: 211586:SO_RS01480
uniprot id: Q8EJZ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThrE exporter (TC 2.A.79) family.
messages: Membrane

211586:SO RS03335
gene id: 211586:SO_RS03335
uniprot id: Q8CX48
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

211586:SO RS01575
gene id: 211586:SO_RS01575
uniprot id: Q8EJX6
names: Function
names: Similarity
messages: Belongs to the SELO family.
messages: Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr or Tyr residues of target proteins (AMPylation).

211586:SO RS14010
gene id: 211586:SO_RS14010
uniprot id: Q8ECV2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.

211586:SO RS18530
gene id: 211586:SO_RS18530
uniprot id: Q8EAC4
names: Similarity
messages: Belongs to the UPF0231 family.

211586:SO RS19590
gene id: 211586:SO_RS19590
uniprot id: Q8E9P2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transpeptidase family. FtsI subfamily.
messages: Catalyzes cross-linking of the peptidoglycan cell wall at the division septum.
messages: Cell inner membrane

211586:SO RS21460
gene id: 211586:SO_RS21460
uniprot id: Q8E8P2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NfuA family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is presumably bound at the interface of two monomers.
messages: Homodimer.
messages: Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins.

211586:SO RS14505
gene id: 211586:SO_RS14505
uniprot id: Q8ECL2
names: Similarity
messages: Belongs to the DEAD box helicase family.

211586:SO RS18845
gene id: 211586:SO_RS18845
uniprot id: Q8EA52
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MetJ family.
messages: Cytoplasm
messages: Does not bind DNA by a helix-turn-helix motif.
messages: Homodimer.
messages: This regulatory protein, when combined with SAM (S-adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis.

211586:SO RS19600
gene id: 211586:SO_RS19600
uniprot id: Q8E9P0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

211586:SO RS07600
gene id: 211586:SO_RS07600
uniprot id: Q8EGF9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Cytoplasm
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
messages: The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.

211586:SO RS22540
gene id: 211586:SO_RS22540
uniprot id: Q8E847
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

211586:SO RS08845
gene id: 211586:SO_RS08845
uniprot id: Q8EFQ4
names: Similarity
messages: Belongs to the peptidase S8 family.

211586:SO RS17190
gene id: 211586:SO_RS17190
uniprot id: Q8EB49
names: Function
names: Similarity
messages: Belongs to the CsgG family.
messages: May be involved in the biogenesis of curli organelles.

211586:SO RS15920
gene id: 211586:SO_RS15920
uniprot id: Q8EBT5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. Homoserine kinase subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
messages: Cytoplasm

211586:SO RS14955
gene id: 211586:SO_RS14955
uniprot id: Q8ECD7
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CheB family.
messages: Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.
messages: Cytoplasm
messages: Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
messages: Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity.

211586:SO RS12140
gene id: 211586:SO_RS12140
uniprot id: Q8EDV9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HflD family.
messages: Cell inner membrane
messages: Cytoplasm

211586:SO RS08945
gene id: 211586:SO_RS08945
uniprot id: Q8EFN3
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Fur family.
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.

211586:SO RS22100
gene id: 211586:SO_RS22100
uniprot id: Q8E8B5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase C chain family.
messages: Cell inner membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.

211586:SO RS05355
gene id: 211586:SO_RS05355
uniprot id: Q8EHQ6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

211586:SO RS07510
gene id: 211586:SO_RS07510
uniprot id: Q8EGH8
names: Activity Regulation
names: Domain
names: Function
names: Similarity
messages: Belongs to the GlnD family.
messages: Has four distinct domains: an N-terminal nucleotidyltransferase (NT) domain responsible for UTase activity, a central HD domain that encodes UR activity, and two C-terminal ACT domains that seem to have a role in glutamine sensing.
messages: Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism.
messages: Uridylyltransferase (UTase) activity is inhibited by glutamine, while glutamine activates uridylyl-removing (UR) activity.

211586:SO RS06520
gene id: 211586:SO_RS06520
uniprot id: Q8EH27
names: Similarity
messages: Belongs to the RutC family.

211586:SO RS04225
gene id: 211586:SO_RS04225
uniprot id: Q8EID9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrB/RnfD family.
messages: Cell inner membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

211586:SO RS16545
gene id: 211586:SO_RS16545
uniprot id: Q8EBH5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell inner membrane
messages: Membrane

211586:SO RS18520
gene id: 211586:SO_RS18520
uniprot id: Q8EAC6
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

211586:SO RS17360
gene id: 211586:SO_RS17360
uniprot id: Q8EB10
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.
messages: Heterodimer composed of CysD, the smaller subunit, and CysN.
messages: With CysD forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway. APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD.

211586:SO RS00785
gene id: 211586:SO_RS00785
uniprot id: Q8EKC5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP H family.
messages: Cell inner membrane
messages: Membrane

211586:SO RS13475
gene id: 211586:SO_RS13475
uniprot id: Q8ED60
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

211586:SO RS07545
gene id: 211586:SO_RS07545
uniprot id: Q8EGH0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

211586:SO RS21020
gene id: 211586:SO_RS21020
uniprot id: Q8E8X6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

211586:SO RS17835
gene id: 211586:SO_RS17835
uniprot id: Q8EAR7
names: Similarity
messages: Belongs to the UPF0162 family.

211586:SO RS22415
gene id: 211586:SO_RS22415
uniprot id: Q8E862
names: Function
messages: Involved in the transposition of the insertion sequence.

211586:SO RS21980
gene id: 211586:SO_RS21980
uniprot id: Q8E8D7
names: Function
names: Similarity
names: Subunit
messages: A GTPase-activating protein (GAP) that modifies Der/EngA GTPase function. May play a role in ribosome biogenesis.
messages: Belongs to the YihI family.
messages: Interacts with Der.

211586:SO RS18400
gene id: 211586:SO_RS18400
uniprot id: Q8EAF3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MlaE permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the ABC transporter complex MlaFEDB, which is involved in a phospholipid transport pathway that maintains lipid asymmetry in the outer membrane by retrograde trafficking of phospholipids from the outer membrane to the inner membrane. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (MlaF), two transmembrane proteins (MlaE), two cytoplasmic solute-binding proteins (MlaB) and six periplasmic solute-binding proteins (MlaD).

211586:SO RS09780
gene id: 211586:SO_RS09780
uniprot id: Q8EF62
names: Function
names: Similarity
messages: Belongs to the CheD family.
messages: Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis.

211586:SO RS07465
gene id: 211586:SO_RS07465
uniprot id: Q8CMJ3
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

211586:SO RS04480
gene id: 211586:SO_RS04480
uniprot id: Q8EI92
names: Similarity
messages: Belongs to the RecJ family.

211586:SO RS11925
gene id: 211586:SO_RS11925
uniprot id: Q8EE01
names: Similarity
messages: Belongs to the iron/ascorbate-dependent oxidoreductase family.

211586:SO RS22200
gene id: 211586:SO_RS22200
uniprot id: Q8E897
names: Similarity
messages: Belongs to the DNA polymerase type-Y family.

211586:SO RS15185
gene id: 211586:SO_RS15185
uniprot id: Q8EC90
names: Function
names: Similarity
messages: Belongs to the FlgM family.
messages: Responsible for the coupling of flagellin expression to flagellar assembly by preventing expression of the flagellin genes when a component of the middle class of proteins is defective. It negatively regulates flagellar genes by inhibiting the activity of FliA by directly binding to FliA.

211586:SO RS01505
gene id: 211586:SO_RS01505
uniprot id: Q8EJZ2
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-I family.

211586:SO RS05235
gene id: 211586:SO_RS05235
uniprot id: Q8EHT1
names: Similarity
messages: Belongs to the DEAD box helicase family.

211586:SO RS14320
gene id: 211586:SO_RS14320
uniprot id: Q8ECP7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the formation of a hydroxyacyl-CoA by addition of water on enoyl-CoA. Also exhibits 3-hydroxyacyl-CoA epimerase and 3-hydroxyacyl-CoA dehydrogenase activities.
messages: Cytoplasm
messages: Heterotetramer of two alpha chains (FadJ) and two beta chains (FadI).
messages: In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family.
messages: In the central section; belongs to the 3-hydroxyacyl-CoA dehydrogenase family.

211586:SO RS04825
gene id: 211586:SO_RS04825
uniprot id: Q8EI17
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobS family.
messages: Cell inner membrane
messages: Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.

211586:SO RS19180
gene id: 211586:SO_RS19180
uniprot id: Q8E9X2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

211586:SO RS18070
gene id: 211586:SO_RS18070
uniprot id: Q8CMJ3
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

211586:SO RS14700
gene id: 211586:SO_RS14700
uniprot id: Q8ECI7
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

211586:SO RS15465
gene id: 211586:SO_RS15465
uniprot id: Q8EC28
names: Subcellular Location Annotation
messages: Membrane

211586:SO RS19695
gene id: 211586:SO_RS19695
uniprot id: Q8E9M3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

211586:SO RS16595
gene id: 211586:SO_RS16595
uniprot id: Q8EBG7
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

211586:SO RS09260
gene id: 211586:SO_RS09260
uniprot id: Q8EFG5
names: Similarity
messages: Belongs to the UPF0276 family.

211586:SO RS02125
gene id: 211586:SO_RS02125
uniprot id: Q8EJM2
names: Similarity
messages: Belongs to the GARS family.

211586:SO RS15025
gene id: 211586:SO_RS15025
uniprot id: Q8ECC2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliM family.
messages: Cell inner membrane
messages: FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
messages: Membrane

211586:SO RS02500
gene id: 211586:SO_RS02500
uniprot id: Q8EJE2
names: Subcellular Location Annotation
messages: Membrane

211586:SO RS17860
gene id: 211586:SO_RS17860
uniprot id: Q8EAR2
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

211586:SO RS13300
gene id: 211586:SO_RS13300
uniprot id: Q8ED94
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

211586:SO RS21740
gene id: 211586:SO_RS21740
uniprot id: Q8E8I7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. KdkA/RfaP family.
messages: Catalyzes the ATP-dependent phosphorylation of the 3-deoxy-D-manno-octulosonic acid (Kdo) residue in Kdo-lipid IV(A) at the 4-OH position.
messages: Cell inner membrane
messages: Membrane

211586:SO RS10975
gene id: 211586:SO_RS10975
uniprot id: Q8EEI8
names: Similarity
messages: Belongs to the peptidase S13 family.

211586:SO RS15655
gene id: 211586:SO_RS15655
uniprot id: Q8EBY7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

211586:SO RS00470
gene id: 211586:SO_RS00470
uniprot id: Q8EKJ7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metallo-dependent hydrolases superfamily. HutI family.
messages: Binds 1 zinc or iron ion per subunit.
messages: Catalyzes the hydrolytic cleavage of the carbon-nitrogen bond in imidazolone-5-propanoate to yield N-formimidoyl-L-glutamate. It is the third step in the universal histidine degradation pathway.
messages: Cytoplasm

211586:SO RS09800
gene id: 211586:SO_RS09800
uniprot id: Q8EF58
names: Similarity
messages: Belongs to the transposase 11 family.

211586:SO RS16095
gene id: 211586:SO_RS16095
uniprot id: Q8CMJ3
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

211586:SO RS14885
gene id: 211586:SO_RS14885
uniprot id: Q8ECF1
names: Subcellular Location Annotation
messages: Membrane

211586:SO RS18295
gene id: 211586:SO_RS18295
uniprot id: Q8EAH2
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with bS18 to 16S ribosomal RNA.

211586:SO RS20990
gene id: 211586:SO_RS20990
uniprot id: Q8E8Y4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

211586:SO RS12765
gene id: 211586:SO_RS12765
uniprot id: K4PSH5
names: Similarity
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.

211586:SO RS17870
gene id: 211586:SO_RS17870
uniprot id: Q8EAR0
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.

211586:SO RS00190
gene id: 211586:SO_RS00190
uniprot id: Q8EKQ2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the aerobic coproporphyrinogen-III oxidase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX.

211586:SO RS03980
gene id: 211586:SO_RS03980
uniprot id: Q8EIJ0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NapD family.
messages: Chaperone for NapA, the catalytic subunit of the periplasmic nitrate reductase. It binds directly and specifically to the twin-arginine signal peptide of NapA, preventing premature interaction with the Tat translocase and premature export.
messages: Cytoplasm
messages: Interacts with the cytoplasmic NapA precursor.

211586:SO RS14725
gene id: 211586:SO_RS14725
uniprot id: Q8ECI2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
messages: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.
messages: Homodimer.

211586:SO RS23430
gene id: 211586:SO_RS23430
uniprot id: Q8EA24
names: Similarity
messages: Belongs to the glycosyl hydrolase 18 family. Chitinase class II subfamily.

211586:SO RS13380
gene id: 211586:SO_RS13380
uniprot id: Q8ED79
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NhaB Na(+)/H(+) (TC 2.A.34) antiporter family.
messages: Cell inner membrane
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

211586:SO RS21110
gene id: 211586:SO_RS21110
uniprot id: Q8CME4
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

211586:SO RS07130
gene id: 211586:SO_RS07130
uniprot id: Q8EGR0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0382 family.
messages: Membrane

211586:SO RS12600
gene id: 211586:SO_RS12600
uniprot id: Q8EDL3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S51 family.
messages: Cytoplasm
messages: Hydrolyzes dipeptides containing N-terminal aspartate residues. May play a role in allowing the cell to use peptide aspartate to spare carbon otherwise required for the synthesis of the aspartate family of amino acids.

211586:SO RS00480
gene id: 211586:SO_RS00480
uniprot id: Q8EKJ5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the urocanase family.
messages: Binds 1 NAD(+) per subunit.
messages: Catalyzes the conversion of urocanate to 4-imidazolone-5-propionate.
messages: Cytoplasm

211586:SO RS03625
gene id: 211586:SO_RS03625
uniprot id: P82177
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LDH/MDH superfamily. MDH type 1 family.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.
messages: Homodimer.

211586:SO RS07555
gene id: 211586:SO_RS07555
uniprot id: Q8EGG8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

211586:SO RS05375
gene id: 211586:SO_RS05375
uniprot id: Q8EHQ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RlpA family.
messages: Cell membrane
messages: Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides.

211586:SO RS08190
gene id: 211586:SO_RS08190
uniprot id: Q8EG25
names: Subcellular Location Annotation
messages: Membrane

211586:SO RS06035
gene id: 211586:SO_RS06035
uniprot id: Q8EHC8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

211586:SO RS04305
gene id: 211586:SO_RS04305
uniprot id: Q8EIC5
names: Similarity
messages: Belongs to the peptidase S45 family.

211586:SO RS17110
gene id: 211586:SO_RS17110
uniprot id: Q8EB65
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

211586:SO RS15615
gene id: 211586:SO_RS15615
uniprot id: Q8EBZ6
names: Similarity
messages: Belongs to the glutathione peroxidase family.

211586:SO RS16195
gene id: 211586:SO_RS16195
uniprot id: Q8EBP5
names: Caution
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the thiamine-monophosphate kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate.

211586:SO RS18200
gene id: 211586:SO_RS18200
uniprot id: Q8EAJ3
names: Subcellular Location Annotation
messages: Membrane

211586:SO RS10740
gene id: 211586:SO_RS10740
uniprot id: Q8EEN5
names: Cofactor
names: Disruption Phenotype
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the quinolinate synthase family. Type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
messages: Cytoplasm
messages: Required for growth on defined medium, and on defined medium supplemented with nictotinic acid.

211586:SO RS17855
gene id: 211586:SO_RS17855
uniprot id: Q8EAR3
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

211586:SO RS19640
gene id: 211586:SO_RS19640
uniprot id: Q8E9N3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.

211586:SO RS22075
gene id: 211586:SO_RS22075
uniprot id: Q8E8C0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

211586:SO RS00630
gene id: 211586:SO_RS00630
uniprot id: Q8EKG2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiC family.
messages: Cytoplasm
messages: Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4-hydroxybenzoate (4HB) for the ubiquinone pathway.

211586:SO RS07520
gene id: 211586:SO_RS07520
uniprot id: Q8EGH5
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

211586:SO RS07605
gene id: 211586:SO_RS07605
uniprot id: Q8EGF8
names: Biotechnology
names: Cofactor
names: Disruption Phenotype
names: Function
names: Induction
messages: Binds 1 Mg(2+) ion per monomer.
messages: Catalyzes the synthesis of cyclic-di-GMP (c-di-GMP) via the condensation of 2 GTP molecules (PubMed:33637573). May be involved in the regulation of formation of solid surface-associated biofilms and pellicles according to environmental conditions (PubMed:33637573).
messages: Deletion of the gene does not affect the growth of MR-1 in batch cultures, but it leads to a strong reduction of c-di-GMP production (PubMed:33637573). It also results in impaired biofilm formation and decreased current generation during growth on electrode surfaces (PubMed:33637573).
messages: Expression is up-regulated under medium flow conditions in electrochemical flow cells (EFCs).
messages: Shewanella oneidensis MR-1 are electrochemically active bacteria (EAB) that form biofilms during growth on electrode surfaces, thereby functioning as effective catalysts for the interconversion between electric and chemical energy (PubMed:33637573). DgcS synthesizes c-di-GMP under medium flow conditions, which activates the formation of biofilms on electrodes via c-di-GMP-dependent signal transduction cascades (PubMed:33637573).

211586:SO RS00295
gene id: 211586:SO_RS00295
uniprot id: Q8EKN5
names: Subcellular Location Annotation
messages: Membrane

211586:SO RS12750
gene id: 211586:SO_RS12750
uniprot id: Q8EDJ3
names: Similarity
messages: Belongs to the peptidase S9A family.

211586:SO RS12605
gene id: 211586:SO_RS12605
uniprot id: Q8EDL2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OpgD/OpgG family.
messages: Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs).
messages: Periplasm

211586:SO RS13385
gene id: 211586:SO_RS13385
uniprot id: P59346
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DsbB family.
messages: Cell inner membrane
messages: Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein.

211586:SO RS09555
gene id: 211586:SO_RS09555
uniprot id: Q8CMJ3
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

211586:SO RS04935
gene id: 211586:SO_RS04935
uniprot id: Q8EHZ2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

211586:SO RS09655
gene id: 211586:SO_RS09655
uniprot id: Q8CVD3
names: Similarity
names: Subunit
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase small subunit family.
messages: Heterodimer of a large and a small subunit.

211586:SO RS17455
gene id: 211586:SO_RS17455
uniprot id: Q8EAY9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YkuD family.
messages: Periplasm

211586:SO RS03655
gene id: 211586:SO_RS03655
uniprot id: Q8EIR2
names: Function
names: Similarity
names: Subunit
messages: Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division.
messages: Belongs to the ZapA family. Type 1 subfamily.
messages: Homodimer. Interacts with FtsZ.

211586:SO RS04495
gene id: 211586:SO_RS04495
uniprot id: Q8EI88
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.
messages: Serves to protect the cell against DNA damage by alkyl hydroperoxides. It can use either NADH or NADPH as electron donor for direct reduction of redox dyes or of alkyl hydroperoxides when combined with the AhpC protein.

211586:SO RS21085
gene id: 211586:SO_RS21085
uniprot id: K4PSX9
names: Similarity
messages: Belongs to the peptidase M16 family.

211586:SO RS20965
gene id: 211586:SO_RS20965
uniprot id: Q8E8Y9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the formate dehydrogenase gamma subunit family.
messages: Membrane

211586:SO RS10365
gene id: 211586:SO_RS10365
uniprot id: Q8EEV4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

211586:SO RS15085
gene id: 211586:SO_RS15085
uniprot id: Q8ECB0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliS family.
messages: cytosol

211586:SO RS00425
gene id: 211586:SO_RS00425
uniprot id: Q8EKK8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAD-like hydrolase superfamily. MasA/MtnC family.
messages: Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene).
messages: Binds 1 Mg(2+) ion per subunit.
messages: Monomer.

211586:SO RS10525
gene id: 211586:SO_RS10525
uniprot id: Q8EES3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family.
messages: Cell inner membrane
messages: Multidrug efflux pump.

211586:SO RS03325
gene id: 211586:SO_RS03325
uniprot id: Q8EIX5
names: Disruption Phenotype
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family.
messages: Cell inner membrane
messages: Deletion of the gene results in a severe decrease in flavin export. Mutants lacking the gene have no defect in reduction of soluble Fe(III), but they are deficient in the rate of insoluble Fe(III) oxide reduction.
messages: Flavin adenine dinucleotide (FAD) transporter that facilitates export of flavin electron shuttles.

211586:SO RS02240
gene id: 211586:SO_RS02240
uniprot id: Q8EJJ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family.
messages: Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate.
messages: Cell inner membrane

211586:SO RS10470
gene id: 211586:SO_RS10470
uniprot id: Q8EET4
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

211586:SO RS18690
gene id: 211586:SO_RS18690
uniprot id: Q8EA87
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. DHA1 family. MdtL (TC 2.A.1.2.22) subfamily.
messages: Cell inner membrane

211586:SO RS08850
gene id: 211586:SO_RS08850
uniprot id: Q8EFQ3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

211586:SO RS14835
gene id: 211586:SO_RS14835
uniprot id: Q8ECG1
names: Subcellular Location Annotation
messages: Membrane

211586:SO RS17875
gene id: 211586:SO_RS17875
uniprot id: Q8EAQ9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

211586:SO RS16500
gene id: 211586:SO_RS16500
uniprot id: Q8EBI6
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

211586:SO RS01070
gene id: 211586:SO_RS01070
uniprot id: Q8EK73
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

211586:SO RS05615
gene id: 211586:SO_RS05615
uniprot id: Q8EHL4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

211586:SO RS22585
gene id: 211586:SO_RS22585
uniprot id: Q8E842
names: Subcellular Location Annotation
messages: Membrane

211586:SO RS12880
gene id: 211586:SO_RS12880
uniprot id: Q8EDG8
names: Function
names: Similarity
messages: Belongs to the DUF177 domain family.
messages: Plays a role in synthesis, processing and/or stability of 23S rRNA.

211586:SO RS16750
gene id: 211586:SO_RS16750
uniprot id: Q8EBE2
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

211586:SO RS21795
gene id: 211586:SO_RS21795
uniprot id: Q8E8H5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TVP38/TMEM64 family.
messages: Cell membrane
messages: Membrane

211586:SO RS03675
gene id: 211586:SO_RS03675
uniprot id: Q8EIQ8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvT family.
messages: The glycine cleavage system catalyzes the degradation of glycine.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

211586:SO RS14510
gene id: 211586:SO_RS14510
uniprot id: Q8ECL1
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MGMT family.
messages: Cytoplasm
messages: Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
messages: This enzyme catalyzes only one turnover and therefore is not strictly catalytic. According to one definition, an enzyme is a biocatalyst that acts repeatedly and over many reaction cycles.

211586:SO RS09600
gene id: 211586:SO_RS09600
uniprot id: Q8EF97
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LpxL/LpxM/LpxP family. LpxM subfamily.
messages: Catalyzes the transfer of an acyl chain from an acyl-[acyl-carrier-protein] (ACP) to a Kdo(2)-(acyl)-lipid IV(A) to form a Kdo(2)-lipid A.
messages: Cell inner membrane

211586:SO RS01050
gene id: 211586:SO_RS01050
uniprot id: Q8EK77
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

211586:SO RS05300
gene id: 211586:SO_RS05300
uniprot id: Q8EHR7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ribose 5-phosphate isomerase family.
messages: Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
messages: Homodimer.

211586:SO RS01250
gene id: 211586:SO_RS01250
uniprot id: Q8EK42
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmC/CycZ/HelC family.
messages: Cell inner membrane
messages: Membrane
messages: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.

211586:SO RS18310
gene id: 211586:SO_RS18310
uniprot id: Q8EAG8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. RlmB subfamily.
messages: Cytoplasm
messages: Specifically methylates the ribose of guanosine 2251 in 23S rRNA.

211586:SO RS20155
gene id: 211586:SO_RS20155
uniprot id: Q8E9E5
names: Subcellular Location Annotation
messages: Membrane

211586:SO RS03620
gene id: 211586:SO_RS03620
uniprot id: Q8EIR6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ArgR family.
messages: Cytoplasm
messages: Regulates arginine biosynthesis genes.

211586:SO RS05100
gene id: 211586:SO_RS05100
uniprot id: Q8EHW0
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

211586:SO RS05835
gene id: 211586:SO_RS05835
uniprot id: Q8EHG5
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

211586:SO RS16660
gene id: 211586:SO_RS16660
uniprot id: Q8EBF4
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

211586:SO RS05900
gene id: 211586:SO_RS05900
uniprot id: Q8EHF1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

211586:SO RS05180
gene id: 211586:SO_RS05180
uniprot id: Q8EHU2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm

211586:SO RS18965
gene id: 211586:SO_RS18965
uniprot id: Q8EA18
names: Similarity
messages: Belongs to the peptidase U62 family.

211586:SO RS10370
gene id: 211586:SO_RS10370
uniprot id: Q8EEV3
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

211586:SO RS05560
gene id: 211586:SO_RS05560
uniprot id: Q8EHM3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.
messages: Cytoplasm
messages: Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.

211586:SO RS04045
gene id: 211586:SO_RS04045
uniprot id: Q8EIH7
names: Function
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

211586:SO RS18430
gene id: 211586:SO_RS18430
uniprot id: Q8EAE7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptA family.
messages: Component of the lipopolysaccharide transport and assembly complex.
messages: Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm.
messages: Periplasm

211586:SO RS17705
gene id: 211586:SO_RS17705
uniprot id: Q8EAU1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell inner membrane
messages: Membrane

211586:SO RS05240
gene id: 211586:SO_RS05240
uniprot id: Q8EHT0
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

211586:SO RS09145
gene id: 211586:SO_RS09145
uniprot id: Q8EFJ4
names: Similarity
messages: Belongs to the ACC deaminase/D-cysteine desulfhydrase family.

211586:SO RS11150
gene id: 211586:SO_RS11150
uniprot id: Q8EEF0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

211586:SO RS07255
gene id: 211586:SO_RS07255
uniprot id: Q8EGN5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC41A transporter family.
messages: Membrane

211586:SO RS09725
gene id: 211586:SO_RS09725
uniprot id: Q8EF72
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TamA family.
messages: Cell outer membrane
messages: Membrane

211586:SO RS17450
gene id: 211586:SO_RS17450
uniprot id: Q8EAZ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. NhaP2 subfamily.
messages: Cell inner membrane
messages: K(+)/H(+) antiporter that extrudes potassium in exchange for external protons and maintains the internal concentration of potassium under toxic levels.

211586:SO RS00025
gene id: 211586:SO_RS00025
uniprot id: Q8EKT5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0161 family.
messages: Cell inner membrane
messages: Could be involved in insertion of integral membrane proteins into the membrane.

211586:SO RS10275
gene id: 211586:SO_RS10275
uniprot id: Q8EEX4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).

211586:SO RS15610
gene id: 211586:SO_RS15610
uniprot id: Q8EBZ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferrochelatase family.
messages: Catalyzes the ferrous insertion into protoporphyrin IX.
messages: Cytoplasm

211586:SO RS02260
gene id: 211586:SO_RS02260
uniprot id: Q8EJJ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

211586:SO RS03505
gene id: 211586:SO_RS03505
uniprot id: Q8EIU1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

211586:SO RS14290
gene id: 211586:SO_RS14290
uniprot id: Q8ECQ4
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmB subfamily.
messages: Methylates large ribosomal subunit protein uL3 on a specific glutamine residue.

211586:SO RS10810
gene id: 211586:SO_RS10810
uniprot id: P46148
names: Function
names: Miscellaneous
names: Subunit
messages: Monomer.
messages: Possesses 4 cysteines which may bind a metal ion (possibly iron).
messages: Regulates anaerobic growth on fumarate, nitrite, Fe(3+), TMAO, DMSO, thiosulfate and sulfite, but not on nitrate nor Mn(4+).

211586:SO RS09690
gene id: 211586:SO_RS09690
uniprot id: Q8EF79
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OpgD/OpgG family.
messages: Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs).
messages: Periplasm

211586:SO RS09720
gene id: 211586:SO_RS09720
uniprot id: Q8EF73
names: Subcellular Location Annotation
messages: Membrane

211586:SO RS20645
gene id: 211586:SO_RS20645
uniprot id: Q8E944
names: Similarity
names: Subunit
messages: Belongs to the MoaE family.
messages: Heterotetramer of 2 MoaD subunits and 2 MoaE subunits. Also stable as homodimer. The enzyme changes between these two forms during catalysis.

211586:SO RS12095
gene id: 211586:SO_RS12095
uniprot id: Q8EDW7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the R-transferase family. Bpt subfamily.
messages: Cytoplasm
messages: Functions in the N-end rule pathway of protein degradation where it conjugates Leu from its aminoacyl-tRNA to the N-termini of proteins containing an N-terminal aspartate or glutamate.

211586:SO RS02945
gene id: 211586:SO_RS02945
uniprot id: Q8EJ54
names: Function
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family. AstD subfamily.
messages: Catalyzes the NAD-dependent reduction of succinylglutamate semialdehyde into succinylglutamate.

211586:SO RS20210
gene id: 211586:SO_RS20210
uniprot id: Q8E9D3
names: Subcellular Location Annotation
messages: Membrane

211586:SO RS08100
gene id: 211586:SO_RS08100
uniprot id: Q8CME4
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

211586:SO RS13335
gene id: 211586:SO_RS13335
uniprot id: Q8ED87
names: Similarity
messages: Belongs to the DnaA family.

211586:SO RS12225
gene id: 211586:SO_RS12225
uniprot id: Q8EDU0
names: Similarity
messages: Belongs to the ner transcriptional regulatory family.

211586:SO RS16450
gene id: 211586:SO_RS16450
uniprot id: Q8EBJ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP H family.
messages: Cell inner membrane
messages: Membrane

211586:SO RS13160
gene id: 211586:SO_RS13160
uniprot id: Q8EDC0
names: Subcellular Location Annotation
messages: Membrane

211586:SO RS04505
gene id: 211586:SO_RS04505
uniprot id: Q8EI85
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M17 family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm
messages: Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity).

211586:SO RS09520
gene id: 211586:SO_RS09520
uniprot id: Q8EFB3
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the C-terminal section; belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: In the N-terminal section; belongs to the histidinol-phosphatase family.

211586:SO RS06310
gene id: 211586:SO_RS06310
uniprot id: Q8CX44
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

211586:SO RS01230
gene id: 211586:SO_RS01230
uniprot id: Q8EK46
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

211586:SO RS09420
gene id: 211586:SO_RS09420
uniprot id: Q8EFD6
names: Subcellular Location Annotation
messages: Membrane

211586:SO RS17630
gene id: 211586:SO_RS17630
uniprot id: Q8EAV8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DEAD box helicase family. RhlE subfamily.
messages: Cytoplasm
messages: DEAD-box RNA helicase involved in ribosome assembly. Has RNA-dependent ATPase activity and unwinds double-stranded RNA.

211586:SO RS17530
gene id: 211586:SO_RS17530
uniprot id: Q8EAX9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0719 family.
messages: Membrane

211586:SO RS02605
gene id: 211586:SO_RS02605
uniprot id: Q8EJB9
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

211586:SO RS06610
gene id: 211586:SO_RS06610
uniprot id: Q8EH09
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

211586:SO RS18480
gene id: 211586:SO_RS18480
uniprot id: Q8EAD4
names: Similarity
messages: Belongs to the transposase 8 family.

211586:SO RS19430
gene id: 211586:SO_RS19430
uniprot id: Q8E9R9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RraA family.
messages: Cytoplasm
messages: Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome.
messages: Homotrimer. Binds to both RNA-binding sites in the C-terminal region of Rne and to RhlB.

211586:SO RS19100
gene id: 211586:SO_RS19100
uniprot id: Q8E9Z0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

211586:SO RS02890
gene id: 211586:SO_RS02890
uniprot id: Q8EJ64
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Rieske iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.
messages: Membrane
messages: The Rieske protein is a high potential 2Fe-2S protein.
messages: The main subunits of complex b-c1 are: cytochrome b, cytochrome c1 and the Rieske protein.

211586:SO RS11385
gene id: 211586:SO_RS11385
uniprot id: Q8EEA6
names: Subcellular Location Annotation
messages: Membrane

211586:SO RS19740
gene id: 211586:SO_RS19740
uniprot id: Q8E9L3
names: Similarity
messages: Belongs to the YicC/YloC family.

211586:SO RS00620
gene id: 211586:SO_RS00620
uniprot id: Q8EKG4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell inner membrane
messages: Membrane

211586:SO RS09000
gene id: 211586:SO_RS09000
uniprot id: Q8EFM1
names: Similarity
messages: Belongs to the intimin/invasin family.

211586:SO RS01385
gene id: 211586:SO_RS01385
uniprot id: Q8EK19
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
messages: Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).
messages: Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
messages: Cytoplasm

211586:SO RS08910
gene id: 211586:SO_RS08910
uniprot id: Q8EFP1
names: Cofactor
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Binds 1 [3Fe-4S] cluster.
messages: Binds 1 [4Fe-4S] cluster.

211586:SO RS10280
gene id: 211586:SO_RS10280
uniprot id: Q8EEX3
names: Subcellular Location Annotation
messages: Cytoplasm

211586:SO RS09505
gene id: 211586:SO_RS09505
uniprot id: Q8CX42
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

211586:SO RS12875
gene id: 211586:SO_RS12875
uniprot id: Q8EDG9
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

211586:SO RS04130
gene id: 211586:SO_RS04130
uniprot id: Q8EIG0
names: Similarity
messages: Belongs to the UPF0270 family.

211586:SO RS08045
gene id: 211586:SO_RS08045
uniprot id: Q8EG54
names: Similarity
messages: Belongs to the phosphohexose mutase family.

211586:SO RS14450
gene id: 211586:SO_RS14450
uniprot id: Q8ECM2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

211586:SO RS12210
gene id: 211586:SO_RS12210
uniprot id: Q8EDU4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

211586:SO RS00995
gene id: 211586:SO_RS00995
uniprot id: Q8EK85
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

211586:SO RS19145
gene id: 211586:SO_RS19145
uniprot id: Q8E9Y1
names: Similarity
messages: Belongs to the nucleoside-specific channel-forming outer membrane porin (Tsx) (TC 1.B.10) family.

211586:SO RS08745
gene id: 211586:SO_RS08745
uniprot id: Q8EFS5
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit B family.

211586:SO RS10435
gene id: 211586:SO_RS10435
uniprot id: Q8EEU0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

211586:SO RS21905
gene id: 211586:SO_RS21905
uniprot id: Q8E8F2
names: Function
names: Similarity
messages: Belongs to the isochorismate synthase family.
messages: Catalyzes the conversion of chorismate to isochorismate.

211586:SO RS05110
gene id: 211586:SO_RS05110
uniprot id: Q8EHV8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrB/RnfD family.
messages: Cell inner membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

211586:SO RS14650
gene id: 211586:SO_RS14650
uniprot id: Q8ECJ8
names: Cofactor
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.
messages: Binds 1 FAD per dimer.

211586:SO RS10060
gene id: 211586:SO_RS10060
uniprot id: Q8EF16
names: Similarity
messages: Belongs to the heat shock protein 70 family.

211586:SO RS21330
gene id: 211586:SO_RS21330
uniprot id: Q8E8S0
names: Cofactor
names: PTM
names: Similarity
messages: Belongs to the NapC/NirT/NrfH family.
messages: Binds 4 heme groups per subunit.

211586:SO RS16650
gene id: 211586:SO_RS16650
uniprot id: Q8EBF6
names: Subcellular Location Annotation
messages: Membrane

211586:SO RS11220
gene id: 211586:SO_RS11220
uniprot id: Q8EED7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ThiC family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
messages: Homodimer.

211586:SO RS01155
gene id: 211586:SO_RS01155
uniprot id: Q8EK58
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

211586:SO RS01650
gene id: 211586:SO_RS01650
uniprot id: Q8EJW1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the isocitrate lyase/PEP mutase superfamily. Methylisocitrate lyase family.
messages: Homotetramer; dimer of dimers.
messages: Involved in the catabolism of short chain fatty acids (SCFA) via the 2-methylcitrate cycle I (propionate degradation route). Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate via an alpha-carboxy-carbanion intermediate.

211586:SO RS16825
gene id: 211586:SO_RS16825
uniprot id: Q8EBC6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic sulfate-binding protein family.
messages: Periplasm

211586:SO RS16980
gene id: 211586:SO_RS16980
uniprot id: Q8EB96
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptD family.
messages: Cell outer membrane
messages: Component of the lipopolysaccharide transport and assembly complex. Interacts with LptE and LptA.
messages: Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane.

211586:SO RS21555
gene id: 211586:SO_RS21555
uniprot id: Q8E8M3
names: Function
names: Similarity
messages: Belongs to the peroxiredoxin family. Prx5 subfamily.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

211586:SO RS11215
gene id: 211586:SO_RS11215
uniprot id: Q8EED8
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

211586:SO RS11135
gene id: 211586:SO_RS11135
uniprot id: Q8EEF3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvB family.
messages: Cytoplasm
messages: Has 3 domains, the large (RuvB-L) and small ATPase (RuvB-S) domains and the C-terminal head (RuvB-H) domain. The head domain binds DNA, while the ATPase domains jointly bind ATP, ADP or are empty depending on the state of the subunit in the translocation cycle. During a single DNA translocation step the structure of each domain remains the same, but their relative positions change.
messages: Homohexamer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time. Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange. Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration. The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration. Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.

211586:SO RS15000
gene id: 211586:SO_RS15000
uniprot id: Q8ECC7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliR/MopE/SpaR family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

211586:SO RS17170
gene id: 211586:SO_RS17170
uniprot id: Q8EB53
names: Similarity
messages: Belongs to the universal stress protein A family.

211586:SO RS07135
gene id: 211586:SO_RS07135
uniprot id: Q8EGQ9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily.
messages: Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA.
messages: Cytoplasm
messages: Monomer.

211586:SO RS15165
gene id: 211586:SO_RS15165
uniprot id: Q8EC94
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of a number of rings mounted on a central rod.

211586:SO RS04595
gene id: 211586:SO_RS04595
uniprot id: Q8EI67
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. RlmC subfamily.
messages: Catalyzes the formation of 5-methyl-uridine at position 747 (m5U747) in 23S rRNA.

211586:SO RS16880
gene id: 211586:SO_RS16880
uniprot id: Q8EBB7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Homodimer.
messages: Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate.

211586:SO RS19595
gene id: 211586:SO_RS19595
uniprot id: Q8E9P1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsL family.
messages: Cell inner membrane
messages: Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.
messages: Part of a complex composed of FtsB, FtsL and FtsQ.

211586:SO RS15795
gene id: 211586:SO_RS15795
uniprot id: Q8EBW1
names: Cofactor
names: Similarity
messages: Belongs to the DNA photolyase class-1 family.
messages: Belongs to the DNA photolyase family.
messages: Binds 1 FAD per subunit.

211586:SO RS11340
gene id: 211586:SO_RS11340
uniprot id: Q8EEB6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M20A family. DapE subfamily.
messages: Binds 2 Zn(2+) or Co(2+) ions per subunit.
messages: Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls.
messages: Homodimer.

211586:SO RS16285
gene id: 211586:SO_RS16285
uniprot id: Q8EBM7
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

211586:SO RS08240
gene id: 211586:SO_RS08240
uniprot id: Q8EG19
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

211586:SO RS00055
gene id: 211586:SO_RS00055
uniprot id: Q8EKS9
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Binds two Mg(2+) per subunit. The magnesium ions form salt bridges with both the protein and the DNA. Can also accept other divalent metal cations, such as Mn(2+) or Ca(2+).
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

211586:SO RS02105
gene id: 211586:SO_RS02105
uniprot id: Q8EJM6
names: Disruption Phenotype
names: Function
names: Subcellular Location Annotation
messages: Affects motility and biofilm formation, and is linked to the regulation of sulfate uptake and assimilation.
messages: Cell membrane
messages: Deletion mutant shows decreased swimming motility and increased biofilm formation under rich growth medium conditions.

211586:SO RS11020
gene id: 211586:SO_RS11020
uniprot id: Q8EEH9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

211586:SO RS05150
gene id: 211586:SO_RS05150
uniprot id: Q8EHV0
names: Function
names: Similarity
messages: Belongs to the bacterioferritin family.
messages: Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex.

211586:SO RS00750
gene id: 211586:SO_RS00750
uniprot id: Q8EKD2
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HSP33 family.
messages: Cytoplasm
messages: Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress.
messages: Under oxidizing conditions two disulfide bonds are formed involving the reactive cysteines. Under reducing conditions zinc is bound to the reactive cysteines and the protein is inactive.

211586:SO RS16790
gene id: 211586:SO_RS16790
uniprot id: Q8EBD3
names: Similarity
messages: Belongs to the MipA/OmpV family.

211586:SO RS12100
gene id: 211586:SO_RS12100
uniprot id: Q8EDW6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

211586:SO RS15010
gene id: 211586:SO_RS15010
uniprot id: Q8ECC5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliP/MopC/SpaP family.
messages: Cell membrane
messages: Membrane
messages: Plays a role in the flagellum-specific transport system.

211586:SO RS03865
gene id: 211586:SO_RS03865
uniprot id: Q8EIL8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. Macrolide exporter (TC 3.A.1.122) family.
messages: Cell inner membrane
messages: Homodimer. Part of the tripartite efflux system MacAB-TolC, which is composed of an inner membrane transporter, MacB, a periplasmic membrane fusion protein, MacA, and an outer membrane component, TolC. The complex forms a large protein conduit and can translocate molecules across both the inner and outer membranes. Interacts with MacA.
messages: Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides.

211586:SO RS06210
gene id: 211586:SO_RS06210
uniprot id: Q8EH90
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH and other flavinylated proteins as well.
messages: Belongs to the SdhE FAD assembly factor family.
messages: Cytoplasm

211586:SO RS18100
gene id: 211586:SO_RS18100
uniprot id: Q8EAL4
names: Similarity
messages: Belongs to the UPF0339 family. Duplicated subfamily.

211586:SO RS12195
gene id: 211586:SO_RS12195
uniprot id: Q8EDU7
names: Function
names: Similarity
messages: Belongs to the class-I DAHP synthase family.
messages: Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP).

211586:SO RS18175
gene id: 211586:SO_RS18175
uniprot id: Q8EAJ8
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

211586:SO RS05890
gene id: 211586:SO_RS05890
uniprot id: Q8EHF3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein PotD/PotF family.
messages: Periplasm
messages: Required for the activity of the bacterial periplasmic transport system of putrescine.

211586:SO RS18215
gene id: 211586:SO_RS18215
uniprot id: Q8EAI9
names: Cofactor
messages: Binds 1 Fe(2+) ion per subunit.

211586:SO RS07630
gene id: 211586:SO_RS07630
uniprot id: Q8EGF2
names: Cofactor
names: Similarity
messages: Belongs to the PHP family.
messages: Binds 3 Zn(2+) ions per subunit.

211586:SO RS16985
gene id: 211586:SO_RS16985
uniprot id: Q8EB95
names: Domain
names: Function
names: Subcellular Location Annotation
messages: Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation.
messages: Periplasm
messages: The PPIase activity resides only in the second parvulin domain. The N-terminal region and the C-terminal tail are necessary and sufficient for the chaperone activity of SurA. The PPIase activity is dispensable for SurA to function as a chaperone. The N-terminal region and the C-terminal tail are also required for porin recognition.

211586:SO RS05550
gene id: 211586:SO_RS05550
uniprot id: Q8EHM5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell inner membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

211586:SO RS12120
gene id: 211586:SO_RS12120
uniprot id: Q8EDW2
names: Cofactor
names: Similarity
messages: Belongs to the monomeric-type IDH family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

211586:SO RS13120
gene id: 211586:SO_RS13120
uniprot id: Q8EDC9
names: Function
names: Similarity
messages: Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.
messages: Belongs to the organic radical-activating enzymes family.

211586:SO RS11940
gene id: 211586:SO_RS11940
uniprot id: Q8EDZ8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
messages: Cell membrane
messages: Monomer.

211586:SO RS18220
gene id: 211586:SO_RS18220
uniprot id: Q8EAI8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

211586:SO RS01060
gene id: 211586:SO_RS01060
uniprot id: Q8EK75
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

211586:SO RS16185
gene id: 211586:SO_RS16185
uniprot id: Q8EBP7
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

211586:SO RS14965
gene id: 211586:SO_RS14965
uniprot id: Q8ECD5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CheZ family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P).

211586:SO RS14960
gene id: 211586:SO_RS14960
uniprot id: Q8ECD6
names: Function
messages: Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors. CheA is autophosphorylated; it can transfer its phosphate group to either CheB or CheY.

211586:SO RS06325
gene id: 211586:SO_RS06325
uniprot id: Q8EH68
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the C-terminal section; belongs to the prephenate/arogenate dehydrogenase family.

211586:SO RS06455
gene id: 211586:SO_RS06455
uniprot id: Q8EH40
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

211586:SO RS19705
gene id: 211586:SO_RS19705
uniprot id: Q8E9M1
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.

211586:SO RS05545
gene id: 211586:SO_RS05545
uniprot id: Q8EHM6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Cell inner membrane
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

211586:SO RS11470
gene id: 211586:SO_RS11470
uniprot id: Q8EE89
names: Similarity
messages: Belongs to the UPF0381 family.

211586:SO RS01915
gene id: 211586:SO_RS01915
uniprot id: Q8EJR4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
messages: Cell inner membrane
messages: Membrane

211586:SO RS23435
gene id: 211586:SO_RS23435
uniprot id: Q8E8W5
names: Similarity
messages: Belongs to the peptidase S8 family.

211586:SO RS04360
gene id: 211586:SO_RS04360
uniprot id: Q8EIB4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

211586:SO RS15630
gene id: 211586:SO_RS15630
uniprot id: Q8EBZ3
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

211586:SO RS00275
gene id: 211586:SO_RS00275
uniprot id: Q8EKN9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

211586:SO RS14925
gene id: 211586:SO_RS14925
uniprot id: Q8ECE4
names: Similarity
messages: Belongs to the type III secretion exporter family.

211586:SO RS22495
gene id: 211586:SO_RS22495
uniprot id: Q8E851
names: Similarity
messages: Belongs to the RelE toxin family.

211586:SO RS13515
gene id: 211586:SO_RS13515
uniprot id: Q8ED55
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Mg(2+). Can also accept Mn(2+).

211586:SO RS17985
gene id: 211586:SO_RS17985
uniprot id: Q8EAN5
names: Similarity
messages: Belongs to the bacterial solute-binding protein ModA family.

211586:SO RS05705
gene id: 211586:SO_RS05705
uniprot id: Q8EHJ5
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

211586:SO RS04645
gene id: 211586:SO_RS04645
uniprot id: Q8EI58
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

211586:SO RS04090
gene id: 211586:SO_RS04090
uniprot id: Q8EIG8
names: Function
names: Similarity
messages: Belongs to the HPPK family.
messages: Catalyzes the transfer of pyrophosphate from adenosine triphosphate (ATP) to 6-hydroxymethyl-7,8-dihydropterin, an enzymatic step in folate biosynthesis pathway.

211586:SO RS10915
gene id: 211586:SO_RS10915
uniprot id: Q8EEK2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dsrC/tusE family.
messages: Cytoplasm
messages: Part of a sulfur-relay system.

211586:SO RS14565
gene id: 211586:SO_RS14565
uniprot id: K4PSJ0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

211586:SO RS20320
gene id: 211586:SO_RS20320
uniprot id: Q8E9A9
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

211586:SO RS06255
gene id: 211586:SO_RS06255
uniprot id: Q8EH81
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

211586:SO RS05205
gene id: 211586:SO_RS05205
uniprot id: Q8EHT7
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

211586:SO RS11805
gene id: 211586:SO_RS11805
uniprot id: Q8EE27
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Monomer.
messages: Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl-glutathione to form glutathione and D-lactic acid.

211586:SO RS19990
gene id: 211586:SO_RS19990
uniprot id: Q8E9H1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenylyl cyclase class-1 family.
messages: Cytoplasm

211586:SO RS02445
gene id: 211586:SO_RS02445
uniprot id: Q8EJF4
names: Similarity
messages: Belongs to the prokaryotic/mitochondrial release factor family.

211586:SO RS03300
gene id: 211586:SO_RS03300
uniprot id: Q8EIY1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbD subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps.

211586:SO RS17750
gene id: 211586:SO_RS17750
uniprot id: Q8EAT0
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

211586:SO RS01115
gene id: 211586:SO_RS01115
uniprot id: Q8EK65
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

211586:SO RS12980
gene id: 211586:SO_RS12980
uniprot id: Q8EDF1
names: Function
names: Similarity
messages: Belongs to the LpxK family.
messages: Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).

211586:SO RS02280
gene id: 211586:SO_RS02280
uniprot id: Q8CVD6
names: Function
names: Similarity
messages: Belongs to the CcmH/CycL/Ccl2/NrfF family.
messages: Possible subunit of a heme lyase.

211586:SO RS01085
gene id: 211586:SO_RS01085
uniprot id: Q8EK71
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

211586:SO RS01985
gene id: 211586:SO_RS01985
uniprot id: Q8EJQ1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA gyrase inhibitor YacG family.
messages: Binds 1 zinc ion.
messages: Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase.
messages: Interacts with GyrB.

211586:SO RS17135
gene id: 211586:SO_RS17135
uniprot id: Q8EB60
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

211586:SO RS16840
gene id: 211586:SO_RS16840
uniprot id: Q8EBC3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. Sulfate/tungstate importer (TC 3.A.1.6) family.
messages: Cell inner membrane
messages: Part of the ABC transporter complex CysAWTP involved in sulfate/thiosulfate import. Responsible for energy coupling to the transport system.
messages: The complex is composed of two ATP-binding proteins (CysA), two transmembrane proteins (CysT and CysW) and a solute-binding protein (CysP).

211586:SO RS16730
gene id: 211586:SO_RS16730
uniprot id: Q8EBE4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamD family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

211586:SO RS18715
gene id: 211586:SO_RS18715
uniprot id: Q8EA81
names: Function
names: Subunit
messages: Homotetramer.
messages: Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.

211586:SO RS18285
gene id: 211586:SO_RS18285
uniprot id: Q8EAH4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein bS6.

211586:SO RS11850
gene id: 211586:SO_RS11850
uniprot id: Q8EE17
names: Similarity
messages: Belongs to the UPF0260 family.

211586:SO RS08370
gene id: 211586:SO_RS08370
uniprot id: Q8EFZ5
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the helicase family. DinG subfamily. Type 1 sub-subfamily.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA-dependent ATPase and 5'-3' DNA helicase.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

211586:SO RS17570
gene id: 211586:SO_RS17570
uniprot id: Q8EAX1
names: Similarity
messages: Belongs to the UPF0111 family.

211586:SO RS08925
gene id: 211586:SO_RS08925
uniprot id: Q8EFN8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

211586:SO RS03355
gene id: 211586:SO_RS03355
uniprot id: Q8EIX1
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

211586:SO RS19540
gene id: 211586:SO_RS19540
uniprot id: Q8E9Q1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

211586:SO RS07685
gene id: 211586:SO_RS07685
uniprot id: Q8EGD9
names: Similarity
messages: Belongs to the UDPGP type 2 family.

211586:SO RS05395
gene id: 211586:SO_RS05395
uniprot id: Q8EHP8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

211586:SO RS06940
gene id: 211586:SO_RS06940
uniprot id: Q8EGU6
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

211586:SO RS10995
gene id: 211586:SO_RS10995
uniprot id: Q8EEI4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the OMP decarboxylase family. Type 1 subfamily.
messages: Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
messages: Homodimer.

211586:SO RS04665
gene id: 211586:SO_RS04665
uniprot id: Q8EI51
names: Similarity
messages: Belongs to the peptidase S11 family.

211586:SO RS02010
gene id: 211586:SO_RS02010
uniprot id: Q8EJP6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP E family.
messages: Cytoplasm

211586:SO RS00775
gene id: 211586:SO_RS00775
uniprot id: Q8EKC7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Cell inner membrane
messages: Component of the type II secretion system inner membrane complex required for the energy-dependent secretion of extracellular factors such as proteases and toxins from the periplasm.
messages: Membrane

211586:SO RS17980
gene id: 211586:SO_RS17980
uniprot id: Q8EAN6
names: Similarity
messages: Belongs to the ModE family.

211586:SO RS12105
gene id: 211586:SO_RS12105
uniprot id: Q8EDW5
names: Similarity
messages: Belongs to the ClpA/ClpB family.

211586:SO RS11025
gene id: 211586:SO_RS11025
uniprot id: Q8EEH8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Monomer.

211586:SO RS12790
gene id: 211586:SO_RS12790
uniprot id: Q8EDI7
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.

211586:SO RS00135
gene id: 211586:SO_RS00135
uniprot id: Q8EKR3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HemG family.
messages: Binds 1 FMN non-covalently per subunit.
messages: Catalyzes the 6-electron oxidation of protoporphyrinogen IX to form protoporphyrin IX; under anaerobic conditions uses menaquinone as an electron acceptor, under aerobic conditions uses ubiquinone as an electron acceptor.
messages: Cell inner membrane

211586:SO RS01695
gene id: 211586:SO_RS01695
uniprot id: Q8EJV2
names: Subcellular Location Annotation
messages: Membrane

211586:SO RS08270
gene id: 211586:SO_RS08270
uniprot id: Q8EG14
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TER reductase family.
messages: Involved in the final reduction of the elongation cycle of fatty acid synthesis (FAS II). Catalyzes the reduction of a carbon-carbon double bond in an enoyl moiety that is covalently linked to an acyl carrier protein (ACP).
messages: Monomer.

211586:SO RS20435
gene id: 211586:SO_RS20435
uniprot id: Q8E986
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S33 family.
messages: Cytoplasm

211586:SO RS19645
gene id: 211586:SO_RS19645
uniprot id: Q8E9N2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Cytoplasm
messages: Homodimer.

211586:SO RS18660
gene id: 211586:SO_RS18660
uniprot id: Q8EA93
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

211586:SO RS05665
gene id: 211586:SO_RS05665
uniprot id: Q8EHK4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DeoC/FbaB aldolase family. DeoC type 2 subfamily.
messages: Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
messages: Cytoplasm

211586:SO RS12585
gene id: 211586:SO_RS12585
uniprot id: Q8EDL7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HupC/HyaC/HydC family.
messages: Membrane

211586:SO RS01325
gene id: 211586:SO_RS01325
uniprot id: P59309
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

211586:SO RS01830
gene id: 211586:SO_RS01830
uniprot id: Q8EJT0
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

211586:SO RS03120
gene id: 211586:SO_RS03120
uniprot id: Q8EJ16
names: Similarity
messages: Belongs to the glycosyl hydrolase 24 family.

211586:SO RS00885
gene id: 211586:SO_RS00885
uniprot id: Q8EKA4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inositol monophosphatase superfamily. CysQ family.
messages: Cell inner membrane
messages: Converts adenosine-3',5'-bisphosphate (PAP) to AMP.

211586:SO RS04245
gene id: 211586:SO_RS04245
uniprot id: Q8EID5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrF family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Cell inner membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: Membrane
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway.

211586:SO RS17095
gene id: 211586:SO_RS17095
uniprot id: Q8EB69
names: Subcellular Location Annotation
messages: Membrane

211586:SO RS02980
gene id: 211586:SO_RS02980
uniprot id: Q8EJ46
names: Caution
names: Function
names: Similarity
messages: Belongs to the 2H phosphoesterase superfamily. ThpR family.
messages: Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'-phosphomonoester.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

211586:SO RS11080
gene id: 211586:SO_RS11080
uniprot id: Q8EEG6
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.

211586:SO RS15580
gene id: 211586:SO_RS15580
uniprot id: Q8EC03
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0126 family.
messages: Membrane

211586:SO RS02285
gene id: 211586:SO_RS02285
uniprot id: Q8EJI7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmF/CycK/Ccl1/NrfE/CcsA family.
messages: Cell inner membrane
messages: Membrane

211586:SO RS13355
gene id: 211586:SO_RS13355
uniprot id: Q8ED83
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

211586:SO RS04940
gene id: 211586:SO_RS04940
uniprot id: Q8EHZ1
names: Similarity
messages: Belongs to the SlyX family.

211586:SO RS05995
gene id: 211586:SO_RS05995
uniprot id: Q8EHD4
names: Function
names: Similarity
messages: Belongs to the HPPK family.
messages: Catalyzes the transfer of pyrophosphate from adenosine triphosphate (ATP) to 6-hydroxymethyl-7,8-dihydropterin, an enzymatic step in folate biosynthesis pathway.

211586:SO RS01320
gene id: 211586:SO_RS01320
uniprot id: Q8EK30
names: Function
names: Similarity
messages: Belongs to the PEPCase type 1 family.
messages: Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.

211586:SO RS07865
gene id: 211586:SO_RS07865
uniprot id: Q8EG99
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

211586:SO RS08775
gene id: 211586:SO_RS08775
uniprot id: Q8EFR9
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

211586:SO RS03420
gene id: 211586:SO_RS03420
uniprot id: Q8EIV5
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the peroxidase family. Peroxidase/catalase subfamily.
messages: Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per dimer.
messages: Formation of the three residue Trp-Tyr-Met cross-link is important for the catalase, but not the peroxidase activity of the enzyme.
messages: Homodimer or homotetramer.

211586:SO RS04630
gene id: 211586:SO_RS04630
uniprot id: Q8EI60
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

211586:SO RS09830
gene id: 211586:SO_RS09830
uniprot id: Q8EF54
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell inner membrane
messages: Membrane

211586:SO RS01960
gene id: 211586:SO_RS01960
uniprot id: Q8EJQ6
names: Similarity
messages: Belongs to the thioredoxin family.

211586:SO RS09715
gene id: 211586:SO_RS09715
uniprot id: Q8EF74
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

211586:SO RS04920
gene id: 211586:SO_RS04920
uniprot id: Q8EHZ5
names: Similarity
messages: Belongs to the peptidase M1 family.

211586:SO RS14440
gene id: 211586:SO_RS14440
uniprot id: Q8ECM4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YajC family.
messages: Cell inner membrane
messages: Membrane

211586:SO RS15140
gene id: 211586:SO_RS15140
uniprot id: Q8ECA0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

211586:SO RS04220
gene id: 211586:SO_RS04220
uniprot id: Q8EIE0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NqrA family.
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

211586:SO RS14250
gene id: 211586:SO_RS14250
uniprot id: Q8ECR2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. PdxB subfamily.
messages: Catalyzes the oxidation of erythronate-4-phosphate to 3-hydroxy-2-oxo-4-phosphonooxybutanoate.
messages: Cytoplasm
messages: Homodimer.

211586:SO RS05535
gene id: 211586:SO_RS05535
uniprot id: Q8EHM8
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

211586:SO RS12770
gene id: 211586:SO_RS12770
uniprot id: Q8EDJ1
names: Subcellular Location Annotation
messages: Membrane

211586:SO RS09415
gene id: 211586:SO_RS09415
uniprot id: Q8EFD7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the glyoxalase I family.
messages: Binds 1 nickel ion per subunit.
messages: Binds 1 zinc ion per subunit. In the homodimer, two zinc ions are bound between subunits.
messages: Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione.

211586:SO RS09760
gene id: 211586:SO_RS09760
uniprot id: Q8EF66
names: Function
messages: Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors. CheA is autophosphorylated; it can transfer its phosphate group to either CheB or CheY.

211586:SO RS04235
gene id: 211586:SO_RS04235
uniprot id: Q8EID7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell inner membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: Membrane
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

211586:SO RS06405
gene id: 211586:SO_RS06405
uniprot id: Q8EH52
names: Similarity
messages: Belongs to the peptidase C56 family.

211586:SO RS07415
gene id: 211586:SO_RS07415
uniprot id: Q8EGJ6
names: Similarity
messages: Belongs to the metallo-beta-lactamase superfamily. Type III sulfatase family.

211586:SO RS05170
gene id: 211586:SO_RS05170
uniprot id: Q8EHU6
names: Similarity
messages: Belongs to the peptidase M17 family.

211586:SO RS09290
gene id: 211586:SO_RS09290
uniprot id: Q8EFF8
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

211586:SO RS19135
gene id: 211586:SO_RS19135
uniprot id: Q8CX36
names: Similarity
messages: Belongs to the band 7/mec-2 family.

211586:SO RS13365
gene id: 211586:SO_RS13365
uniprot id: P59352
names: Similarity
messages: Belongs to the UPF0229 family.

211586:SO RS07740
gene id: 211586:SO_RS07740
uniprot id: Q8EGC7
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

211586:SO RS12930
gene id: 211586:SO_RS12930
uniprot id: Q8EDG1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: Binds 1 zinc ion.
messages: Homodimer.
messages: This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.

211586:SO RS09155
gene id: 211586:SO_RS09155
uniprot id: Q8EFJ2
names: Similarity
messages: Belongs to the ribose-phosphate pyrophosphokinase family.

211586:SO RS12490
gene id: 211586:SO_RS12490
uniprot id: Q8EDN8
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

211586:SO RS15055
gene id: 211586:SO_RS15055
uniprot id: Q8ECB6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliG family.
messages: Cell inner membrane
messages: FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
messages: Membrane

211586:SO RS10410
gene id: 211586:SO_RS10410
uniprot id: Q8EEU5
names: Function
names: Similarity
messages: Belongs to the heat shock protein 70 family.
messages: Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB.

211586:SO RS18150
gene id: 211586:SO_RS18150
uniprot id: Q8EAK3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family. ParE type 1 subfamily.
messages: Heterotetramer composed of ParC and ParE.
messages: Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.

211586:SO RS01995
gene id: 211586:SO_RS01995
uniprot id: Q8EJP9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

211586:SO RS22105
gene id: 211586:SO_RS22105
uniprot id: Q8E8B4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase A chain family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.

211586:SO RS10825
gene id: 211586:SO_RS10825
uniprot id: Q8EEM0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

211586:SO RS12055
gene id: 211586:SO_RS12055
uniprot id: Q8EDX5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dCTP deaminase family.
messages: Catalyzes the deamination of dCTP to dUTP.
messages: Homotrimer.

211586:SO RS20985
gene id: 211586:SO_RS20985
uniprot id: Q8E8Y5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the formate dehydrogenase gamma subunit family.
messages: Membrane

211586:SO RS15930
gene id: 211586:SO_RS15930
uniprot id: Q8EBT2
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

211586:SO RS12855
gene id: 211586:SO_RS12855
uniprot id: Q8EDH3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

211586:SO RS20415
gene id: 211586:SO_RS20415
uniprot id: Q8E990
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Also exhibits azoreductase activity. Catalyzes the reductive cleavage of the azo bond in aromatic azo compounds to the corresponding amines.
messages: Belongs to the azoreductase type 1 family.
messages: Binds 1 FMN per subunit.
messages: Homodimer.
messages: Quinone reductase that provides resistance to thiol-specific stress caused by electrophilic quinones.

211586:SO RS17415
gene id: 211586:SO_RS17415
uniprot id: Q8EAZ7
names: Function
names: Similarity
messages: Belongs to the AlaDH/PNT family.
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

211586:SO RS04550
gene id: 211586:SO_RS04550
uniprot id: P83223
names: Cofactor
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Binds 1 FAD per subunit.
messages: Binds 4 heme c groups covalently per monomer.
messages: By anaerobiosis and fumarate.
messages: Catalyzes fumarate reduction using artificial electron donors such as methyl viologen. The physiological reductant is unknown, but evidence indicates that flavocytochrome c participates in electron transfer from formate to fumarate and possibly also to trimethylamine oxide (TMAO). This enzyme is essentially unidirectional (By similarity).
messages: In the C-terminal section; belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
messages: Monomer.
messages: Periplasm

211586:SO RS01730
gene id: 211586:SO_RS01730
uniprot id: Q8EJU6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

211586:SO RS01380
gene id: 211586:SO_RS01380
uniprot id: Q8EK20
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Monomer.

211586:SO RS22070
gene id: 211586:SO_RS22070
uniprot id: Q8E8C1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

211586:SO RS02490
gene id: 211586:SO_RS02490
uniprot id: Q8EJE4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

211586:SO RS16180
gene id: 211586:SO_RS16180
uniprot id: Q8EBP8
names: Subcellular Location Annotation
messages: Membrane

211586:SO RS13500
gene id: 211586:SO_RS13500
uniprot id: Q8ED58
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycyl radical enzyme (GRE) family. PFL subfamily.
messages: Cytoplasm
messages: Homodimer.

211586:SO RS10555
gene id: 211586:SO_RS10555
uniprot id: Q8EER7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

211586:SO RS20925
gene id: 211586:SO_RS20925
uniprot id: Q8E8Z7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FdhD family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH.

211586:SO RS15360
gene id: 211586:SO_RS15360
uniprot id: Q8EC52
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

211586:SO RS14445
gene id: 211586:SO_RS14445
uniprot id: Q8ECM3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.

211586:SO RS09500
gene id: 211586:SO_RS09500
uniprot id: Q8EFB6
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the C-terminal section; belongs to the PRA-PH family.
messages: In the N-terminal section; belongs to the PRA-CH family.

211586:SO RS14025
gene id: 211586:SO_RS14025
uniprot id: Q8ECU9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

211586:SO RS06765
gene id: 211586:SO_RS06765
uniprot id: Q8EGY1
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

211586:SO RS19050
gene id: 211586:SO_RS19050
uniprot id: Q8EA00
names: Similarity
messages: Belongs to the GSP E family.

211586:SO RS14265
gene id: 211586:SO_RS14265
uniprot id: Q8ECQ8
names: Similarity
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.

211586:SO RS11420
gene id: 211586:SO_RS11420
uniprot id: Q8EE98
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

211586:SO RS17465
gene id: 211586:SO_RS17465
uniprot id: K4PU41
names: Similarity
messages: Belongs to the peptidase M16 family.

211586:SO RS03580
gene id: 211586:SO_RS03580
uniprot id: Q8EIS4
names: Similarity
messages: Belongs to the P(II) protein family.

211586:SO RS14905
gene id: 211586:SO_RS14905
uniprot id: K4PU14
names: Subcellular Location Annotation
messages: Membrane

211586:SO RS20785
gene id: 211586:SO_RS20785
uniprot id: Q8E915
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

211586:SO RS03340
gene id: 211586:SO_RS03340
uniprot id: Q8EIX4
names: Disruption Phenotype
names: Function
names: Induction
names: Similarity
names: Subunit
messages: Antitoxin component of a type II toxin-antitoxin (TA) system. Neutralizes the toxic effect of cognate toxin HipA; overexpression in wild-type or a hipAB deletion temporarily inhibits cell growth. Binds operator DNA; in the ternary phosphoserine-HipA-HipB-DNA complex the DNA is bent about 125 degrees.
messages: Belongs to the HipB antitoxin family.
messages: Essential; a single hipB deletion cannot be made, probably due to toxicity of HipA.
messages: Expressed in late-exponential phase; part of the hipBA operon.
messages: Homodimer, binds DNA. Forms a HipA(2)HipB(2)-DNA complex with cognate toxin HipA; has higher affinity for the latter when HipB is prebound to DNA and HipA is phosphorylated.

211586:SO RS15645
gene id: 211586:SO_RS15645
uniprot id: Q8EBY9
names: Similarity
messages: Belongs to the UPF0235 family.

211586:SO RS08550
gene id: 211586:SO_RS08550
uniprot id: Q8EFV9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thioester dehydratase family. FabA subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)-decenoyl-ACP. Can catalyze the dehydratase reaction for beta-hydroxyacyl-ACPs with saturated chain lengths up to 16:0, being most active on intermediate chain length.

211586:SO RS01725
gene id: 211586:SO_RS01725
uniprot id: Q8EJU7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

211586:SO RS10670
gene id: 211586:SO_RS10670
uniprot id: Q8EEQ0
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CheB family.
messages: Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.
messages: Cytoplasm
messages: Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
messages: Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity.

211586:SO RS21630
gene id: 211586:SO_RS21630
uniprot id: Q8E8K8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. Sulfate/tungstate importer (TC 3.A.1.6) family.
messages: Cell inner membrane
messages: Part of the ABC transporter complex CysAWTP involved in sulfate/thiosulfate import. Responsible for energy coupling to the transport system.
messages: The complex is composed of two ATP-binding proteins (CysA), two transmembrane proteins (CysT and CysW) and a solute-binding protein (CysP).

211586:SO RS11130
gene id: 211586:SO_RS11130
uniprot id: Q8EEF5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

211586:SO RS12535
gene id: 211586:SO_RS12535
uniprot id: Q8EDM8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

211586:SO RS07185
gene id: 211586:SO_RS07185
uniprot id: Q8EGP9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Xni family.
messages: Binds 1 K(+) per subunit. The potassium ion strongly increases the affinity for DNA.
messages: Binds 2 Mg(2+) per subunit. Only one magnesium ion has a direct interaction with the protein, the other interactions are indirect.
messages: Has flap endonuclease activity. During DNA replication, flap endonucleases cleave the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment.

211586:SO RS12720
gene id: 211586:SO_RS12720
uniprot id: Q8EDJ9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Pal lipoprotein family.
messages: Cell outer membrane
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

211586:SO RS16050
gene id: 211586:SO_RS16050
uniprot id: Q8EBR6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.
messages: Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins.
messages: Cytoplasm

211586:SO RS09495
gene id: 211586:SO_RS09495
uniprot id: Q8EFB8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid/polyamine transporter 2 family. Mtr/TnaB/TyrP permease subfamily.
messages: Cell inner membrane
messages: Involved in transporting aromatic amino acids across the cytoplasmic membrane.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

211586:SO RS22875
gene id: 211586:SO_RS22875
uniprot id: Q8E801
names: Function
names: Similarity
messages: Belongs to the esterase D family.
messages: Serine hydrolase involved in the detoxification of formaldehyde.

211586:SO RS14880
gene id: 211586:SO_RS14880
uniprot id: Q8ECF2
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

211586:SO RS00010
gene id: 211586:SO_RS00010
uniprot id: Q8EKT7
names: Subcellular Location Annotation
messages: Membrane

211586:SO RS04880
gene id: 211586:SO_RS04880
uniprot id: Q8EI05
names: Subcellular Location Annotation
messages: Membrane

211586:SO RS04735
gene id: 211586:SO_RS04735
uniprot id: Q8EI36
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 23 kDa subunit family.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell inner membrane
messages: NDH-1 is composed of 13 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

211586:SO RS02875
gene id: 211586:SO_RS02875
uniprot id: Q8EJ68
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

211586:SO RS05575
gene id: 211586:SO_RS05575
uniprot id: Q8EHM0
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

211586:SO RS20330
gene id: 211586:SO_RS20330
uniprot id: Q8E9A7
names: Subcellular Location Annotation
messages: Membrane

211586:SO RS04500
gene id: 211586:SO_RS04500
uniprot id: Q8EI86
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

211586:SO RS05990
gene id: 211586:SO_RS05990
uniprot id: Q8EHD5
names: Function
names: Similarity
messages: Belongs to the DHNA family.
messages: Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin.

211586:SO RS05360
gene id: 211586:SO_RS05360
uniprot id: Q8EHQ5
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LipB family.
messages: Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
messages: Cytoplasm
messages: In the reaction, the free carboxyl group of octanoic acid is attached via an amide linkage to the epsilon-amino group of a specific lysine residue of lipoyl domains of lipoate-dependent enzymes.

211586:SO RS13305
gene id: 211586:SO_RS13305
uniprot id: Q8ED93
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48 family. BepA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Functions as both a chaperone and a metalloprotease. Maintains the integrity of the outer membrane by promoting either the assembly or the elimination of outer membrane proteins, depending on their folding state.
messages: Periplasm

211586:SO RS22125
gene id: 211586:SO_RS22125
uniprot id: Q8E8B0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Specifically methylates the N7 position of guanine in position 527 of 16S rRNA.

211586:SO RS10070
gene id: 211586:SO_RS10070
uniprot id: Q8EF14
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

211586:SO RS18825
gene id: 211586:SO_RS18825
uniprot id: Q8EA56
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

211586:SO RS10850
gene id: 211586:SO_RS10850
uniprot id: Q8EEL5
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Binds 1 copper ion per subunit, denoted as copper B.
messages: Binds 2 heme groups per subunit, denoted as high- and low-spin.
messages: Membrane

211586:SO RS20650
gene id: 211586:SO_RS20650
uniprot id: Q8E943
names: Similarity
messages: Belongs to the MoaD family.

211586:SO RS17610
gene id: 211586:SO_RS17610
uniprot id: Q8EAW2
names: Subcellular Location Annotation
messages: Membrane

211586:SO RS01810
gene id: 211586:SO_RS01810
uniprot id: Q8CMJ3
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

211586:SO RS03555
gene id: 211586:SO_RS03555
uniprot id: Q8EIT1
names: Subcellular Location Annotation
messages: Membrane

211586:SO RS00510
gene id: 211586:SO_RS00510
uniprot id: Q8EKI8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SelA family.
messages: Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis.
messages: Cytoplasm

211586:SO RS02390
gene id: 211586:SO_RS02390
uniprot id: Q8EJG7
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

211586:SO RS12115
gene id: 211586:SO_RS12115
uniprot id: Q8EDW3
names: Subcellular Location Annotation
messages: Cytoplasm

211586:SO RS08905
gene id: 211586:SO_RS08905
uniprot id: Q8EFP2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
messages: Cell inner membrane
messages: Membrane

211586:SO RS16400
gene id: 211586:SO_RS16400
uniprot id: Q8CVD2
names: Similarity
messages: Belongs to the glycosyl hydrolase 20 family.

211586:SO RS10000
gene id: 211586:SO_RS10000
uniprot id: Q8EF26
names: Similarity
messages: Belongs to the UPF0352 family.

211586:SO RS11360
gene id: 211586:SO_RS11360
uniprot id: Q8EEB1
names: Disruption Phenotype
names: Function
names: Miscellaneous
names: Similarity
messages: A double kdnA/kdnB deletion mutant shows increased sensitivity to polymyxin B and bile salts.
messages: Belongs to the DegT/DnrJ/EryC1 family.
messages: Catalyzes the second (last) step of the biosynthesis of Kdo8N (8-amino-3,8-dideoxy-D-manno-octulosonate) from Kdo (3-deoxy-D-manno-octulosonate).
messages: Kdo8N is found in lipopolysaccharides of members of the Shewanella genus.

211586:SO RS18935
gene id: 211586:SO_RS18935
uniprot id: Q8EA28
names: Subcellular Location Annotation
messages: Membrane

211586:SO RS01275
gene id: 211586:SO_RS01275
uniprot id: Q8EK37
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmF/CycK/Ccl1/NrfE/CcsA family.
messages: Cell inner membrane
messages: Membrane

211586:SO RS08245
gene id: 211586:SO_RS08245
uniprot id: Q8EG18
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

211586:SO RS17025
gene id: 211586:SO_RS17025
uniprot id: Q8EB85
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThrE exporter (TC 2.A.79) family.
messages: Membrane

211586:SO RS04820
gene id: 211586:SO_RS04820
uniprot id: Q8EI18
names: Function
names: Similarity
messages: Belongs to the CobT family.
messages: Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB).

211586:SO RS09230
gene id: 211586:SO_RS09230
uniprot id: Q8EFH1
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

211586:SO RS12715
gene id: 211586:SO_RS12715
uniprot id: Q8EDK0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CpoB family.
messages: Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division.
messages: Periplasm

211586:SO RS08920
gene id: 211586:SO_RS08920
uniprot id: Q8EFN9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 1 lipoyl cofactor covalently.
messages: E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).

211586:SO RS00175
gene id: 211586:SO_RS00175
uniprot id: Q8EKQ5
names: Similarity
messages: Belongs to the Smg family.

211586:SO RS00195
gene id: 211586:SO_RS00195
uniprot id: Q8EKQ1
names: Similarity
messages: Belongs to the truncated hemoglobin family. Group II subfamily.

211586:SO RS02300
gene id: 211586:SO_RS02300
uniprot id: Q8EJI4
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

211586:SO RS12190
gene id: 211586:SO_RS12190
uniprot id: Q8EDU8
names: Function
names: Similarity
messages: Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PSRP subfamily.
messages: Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation/dephosphorylation.

211586:SO RS06660
gene id: 211586:SO_RS06660
uniprot id: Q8EGZ8
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

211586:SO RS11950
gene id: 211586:SO_RS11950
uniprot id: Q8EDZ6
names: Subcellular Location Annotation
messages: Membrane

211586:SO RS01200
gene id: 211586:SO_RS01200
uniprot id: Q8EK50
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell inner membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

211586:SO RS16075
gene id: 211586:SO_RS16075
uniprot id: Q8EBR1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsB family.
messages: Cell inner membrane
messages: Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.
messages: Part of a complex composed of FtsB, FtsL and FtsQ.

211586:SO RS01980
gene id: 211586:SO_RS01980
uniprot id: Q8EJQ2
names: Similarity
messages: Belongs to the Nudix hydrolase family.

211586:SO RS06885
gene id: 211586:SO_RS06885
uniprot id: Q8EGW0
names: Similarity
messages: Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family.

211586:SO RS05370
gene id: 211586:SO_RS05370
uniprot id: Q8EHQ3
names: Function
names: Similarity
messages: Belongs to the peptidase S11 family.
messages: Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors.

211586:SO RS20105
gene id: 211586:SO_RS20105
uniprot id: Q8E9F6
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

211586:SO RS15430
gene id: 211586:SO_RS15430
uniprot id: Q8EC35
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamB family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

211586:SO RS07735
gene id: 211586:SO_RS07735
uniprot id: Q8EGC8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MetA family.
messages: Cytoplasm
messages: Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine.

211586:SO RS18565
gene id: 211586:SO_RS18565
uniprot id: Q8EAB6
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FBPase class 1 family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.

211586:SO RS00325
gene id: 211586:SO_RS00325
uniprot id: Q8EKM9
names: Similarity
messages: Belongs to the HipA Ser/Thr kinase family.

211586:SO RS19710
gene id: 211586:SO_RS19710
uniprot id: Q8E9M0
names: Function
names: Similarity
messages: Belongs to the dUTPase family.
messages: This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

211586:SO RS19675
gene id: 211586:SO_RS19675
uniprot id: Q8E9M6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EamA transporter family.
messages: Membrane

211586:SO RS15660
gene id: 211586:SO_RS15660
uniprot id: Q8EBY6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

211586:SO RS09515
gene id: 211586:SO_RS09515
uniprot id: Q8EFB4
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

211586:SO RS11435
gene id: 211586:SO_RS11435
uniprot id: Q8EE95
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

211586:SO RS04625
gene id: 211586:SO_RS04625
uniprot id: Q8EI61
names: Similarity
messages: In the C-terminal section; belongs to the prokaryotic molybdopterin-containing oxidoreductase family.

211586:SO RS22090
gene id: 211586:SO_RS22090
uniprot id: Q8E8B7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase delta chain family.
messages: Cell inner membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

211586:SO RS14080
gene id: 211586:SO_RS14080
uniprot id: Q8ECT7
names: Cofactor
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.
messages: Probably binds two magnesium or manganese ions per subunit.

211586:SO RS01310
gene id: 211586:SO_RS01310
uniprot id: Q8EK32
names: Disruption Phenotype
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CinA family.
messages: Homodimer.
messages: Not essential for growth on defined medium, loss of NMN amidohydrolase activity.
messages: One of the key enzymes of the pyridine nucleotide cycle which permits cells to recycle the by products of NAD consumption back to NAD. Has no activity on NAD, NADP, nicotinamide or nicotinamide riboside.

211586:SO RS03575
gene id: 211586:SO_RS03575
uniprot id: Q8EIS5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Membrane

211586:SO RS01080
gene id: 211586:SO_RS01080
uniprot id: Q8EK72
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

211586:SO RS05730
gene id: 211586:SO_RS05730
uniprot id: Q8EHJ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TorD/DmsD family. TorD subfamily.
messages: Cytoplasm
messages: Involved in the biogenesis of TorA. Acts on TorA before the insertion of the molybdenum cofactor and, as a result, probably favors a conformation of the apoenzyme that is competent for acquiring the cofactor.

211586:SO RS06130
gene id: 211586:SO_RS06130
uniprot id: Q8EHA7
names: Function
names: Similarity
messages: Belongs to the PNP/UDP phosphorylase family. MtnN subfamily.
messages: Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively. Also cleaves 5'-deoxyadenosine, a toxic by-product of radical S-adenosylmethionine (SAM) enzymes, into 5-deoxyribose and adenine.

211586:SO RS06925
gene id: 211586:SO_RS06925
uniprot id: Q8EGU9
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

211586:SO RS03835
gene id: 211586:SO_RS03835
uniprot id: Q8EIM3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

211586:SO RS06600
gene id: 211586:SO_RS06600
uniprot id: Q8EH11
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

211586:SO RS08895
gene id: 211586:SO_RS08895
uniprot id: Q8EFP3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome b560 family.
messages: Membrane
messages: Membrane-anchoring subunit of succinate dehydrogenase (SDH).
messages: Part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur protein, plus two membrane-anchoring proteins, SdhC and SdhD. The complex can form homotrimers.
messages: The heme is bound between the two transmembrane subunits.

211586:SO RS20440
gene id: 211586:SO_RS20440
uniprot id: Q8E985
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0761 family.
messages: Cell inner membrane

211586:SO RS04230
gene id: 211586:SO_RS04230
uniprot id: Q8EID8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrC family.
messages: Cell inner membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

211586:SO RS20040
gene id: 211586:SO_RS20040
uniprot id: Q8E9G5
names: Subcellular Location Annotation
messages: Membrane

211586:SO RS01220
gene id: 211586:SO_RS01220
uniprot id: P59131
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

211586:SO RS03810
gene id: 211586:SO_RS03810
uniprot id: Q8CVD5
names: Function
names: Subcellular Location Annotation
messages: Periplasm
messages: Transfers electrons from cytochrome c551 to cytochrome oxidase.

211586:SO RS22130
gene id: 211586:SO_RS22130
uniprot id: Q8E8A9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

211586:SO RS03305
gene id: 211586:SO_RS03305
uniprot id: Q8EIY0
names: Similarity
messages: Belongs to the CutA family.

211586:SO RS16830
gene id: 211586:SO_RS16830
uniprot id: Q8EBC5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the ABC transporter complex (TC 3.A.1.6.1) involved in sulfate/thiosulfate import.
messages: Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (CysA), two transmembrane proteins (CysT and CysW) and a solute-binding protein (CysP).

211586:SO RS00780
gene id: 211586:SO_RS00780
uniprot id: Q8EKC6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP G family.
messages: Cell inner membrane
messages: Membrane

211586:SO RS03475
gene id: 211586:SO_RS03475
uniprot id: Q8EIU5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

211586:SO RS06305
gene id: 211586:SO_RS06305
uniprot id: Q8EH71
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein uS19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein uS19.

211586:SO RS02465
gene id: 211586:SO_RS02465
uniprot id: Q8EJE9
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

211586:SO RS00660
gene id: 211586:SO_RS00660
uniprot id: Q8EKF5
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

211586:SO RS21095
gene id: 211586:SO_RS21095
uniprot id: Q8E8W2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

211586:SO RS08000
gene id: 211586:SO_RS08000
uniprot id: Q8EG65
names: Disruption Phenotype
names: Function
names: Similarity
messages: Belongs to the AB hydrolase superfamily.
messages: Deletion of the entire oleABCD gene cluster leads to the complete absence of nonpolar extractable products. The oleABCD deletion strain shows a significantly longer lag phase than the wild-type strain when shifted to a lower temperature.
messages: Involved in olefin biosynthesis (PubMed:20418444). Catalyzes the elimination of carbon dioxide from beta-lactones to form the final olefin product (By similarity). The S.oneidensis oleABCD genes produce 3,6,9,12,15,19,22,25,28-hentriacontanonaene, which may aid the cells in adapting to a sudden drop in temperature (PubMed:20418444).

211586:SO RS21310
gene id: 211586:SO_RS21310
uniprot id: Q8E8S4
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily. RsmD family.
messages: Specifically methylates the guanine in position 966 of 16S rRNA in the assembled 30S particle.

211586:SO RS12045
gene id: 211586:SO_RS12045
uniprot id: Q8EDX7
names: Function
names: Similarity
messages: Belongs to the transglycosylase MltG family.
messages: Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.

211586:SO RS02665
gene id: 211586:SO_RS02665
uniprot id: Q8EJA7
names: Similarity
messages: Belongs to the formate--tetrahydrofolate ligase family.

211586:SO RS16820
gene id: 211586:SO_RS16820
uniprot id: Q8EBC7
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

211586:SO RS00505
gene id: 211586:SO_RS00505
uniprot id: P59188
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FdhE family.
messages: Cytoplasm
messages: Necessary for formate dehydrogenase activity.

211586:SO RS05135
gene id: 211586:SO_RS05135
uniprot id: Q8EHV3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ApbE family.
messages: Cell inner membrane
messages: Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein.
messages: Magnesium. Can also use manganese.

211586:SO RS11825
gene id: 211586:SO_RS11825
uniprot id: Q8EE23
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class II aldolase/RraA-like family.
messages: Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2-oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions (By similarity).
messages: Divalent metal cation.
messages: Homotrimer.

211586:SO RS08965
gene id: 211586:SO_RS08965
uniprot id: Q8EFM9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Mediates influx of magnesium ions.
messages: Membrane

211586:SO RS04980
gene id: 211586:SO_RS04980
uniprot id: Q8EHY3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GDT1 family.
messages: Membrane

211586:SO RS02185
gene id: 211586:SO_RS02185
uniprot id: Q8EJK8
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.

211586:SO RS15620
gene id: 211586:SO_RS15620
uniprot id: Q8EBZ5
names: Similarity
messages: Belongs to the GSP E family.