206403:YH65 RS01575
gene id: 206403:YH65_RS01575
uniprot id: A0A7U4LZT3
names: Subcellular Location Annotation
messages: Membrane

206403:YH65 RS04660
gene id: 206403:YH65_RS04660
uniprot id: A0A7U4RQK1
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

206403:YH65 RS05445
gene id: 206403:YH65_RS05445
uniprot id: A0A7U4M126
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
messages: Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).
messages: Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
messages: Cytoplasm

206403:YH65 RS08715
gene id: 206403:YH65_RS08715
uniprot id: A0A7U4RR64
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SoxA family.
messages: Binds 2 heme groups per subunit.
messages: Heterodimer of SoxA and SoxX.
messages: Periplasm

206403:YH65 RS02275
gene id: 206403:YH65_RS02275
uniprot id: A0A7U4M014
names: Function
names: Similarity
names: Subunit
messages: Catalyzes the ADP transfer from ATP to D-glycero-beta-D-manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose.
messages: Catalyzes the phosphorylation of D-glycero-D-manno-heptose 7-phosphate at the C-1 position to selectively form D-glycero-beta-D-manno-heptose-1,7-bisphosphate.
messages: Homodimer.
messages: In the C-terminal section; belongs to the cytidylyltransferase family.
messages: In the N-terminal section; belongs to the carbohydrate kinase PfkB family.

206403:YH65 RS04845
gene id: 206403:YH65_RS04845
uniprot id: A0A7U4RQK9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas1 homodimer.

206403:YH65 RS03505
gene id: 206403:YH65_RS03505
uniprot id: A0A7U4RQD4
names: Cofactor
names: Similarity
messages: Belongs to the MsrB Met sulfoxide reductase family.
messages: Binds 1 zinc ion per subunit. The zinc ion is important for the structural integrity of the protein.

206403:YH65 RS10605
gene id: 206403:YH65_RS10605
uniprot id: A0A7U4RRF8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

206403:YH65 RS02605
gene id: 206403:YH65_RS02605
uniprot id: A0A7U4M043
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family.

206403:YH65 RS01760
gene id: 206403:YH65_RS01760
uniprot id: A0A7U4RQ16
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the GTP cyclohydrolase II family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.

206403:YH65 RS00480
gene id: 206403:YH65_RS00480
uniprot id: A0A7U4LZJ0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 1 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.

206403:YH65 RS11045
gene id: 206403:YH65_RS11045
uniprot id: A0A7U4M2X0
names: Similarity
messages: Belongs to the bacterial secretin family.

206403:YH65 RS09865
gene id: 206403:YH65_RS09865
uniprot id: A0A7U4M2H4
names: Similarity
messages: Belongs to the thioredoxin family.

206403:YH65 RS02990
gene id: 206403:YH65_RS02990
uniprot id: A0A7U4RQ89
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

206403:YH65 RS05100
gene id: 206403:YH65_RS05100
uniprot id: A0A7U4RQK6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0073 (Hly-III) family.
messages: Membrane

206403:YH65 RS07195
gene id: 206403:YH65_RS07195
uniprot id: A0A7U4M1L2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Cell membrane
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

206403:YH65 RS00945
gene id: 206403:YH65_RS00945
uniprot id: A0A7U4LZJ8
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

206403:YH65 RS04310
gene id: 206403:YH65_RS04310
uniprot id: A0A7U4M0Q4
names: Subcellular Location Annotation
messages: Membrane

206403:YH65 RS00820
gene id: 206403:YH65_RS00820
uniprot id: A0A7U4LZM4
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

206403:YH65 RS11120
gene id: 206403:YH65_RS11120
uniprot id: A0A7U4M2Y1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvC family.
messages: Binds 2 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer which binds Holliday junction (HJ) DNA. The HJ becomes 2-fold symmetrical on binding to RuvC with unstacked arms; it has a different conformation from HJ DNA in complex with RuvA. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair. Endonuclease that resolves HJ intermediates. Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction. The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'. Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange. HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

206403:YH65 RS04490
gene id: 206403:YH65_RS04490
uniprot id: A0A7U4RQJ1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxA subfamily.
messages: Cytoplasm
messages: Homotrimer.
messages: Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

206403:YH65 RS04195
gene id: 206403:YH65_RS04195
uniprot id: A0A7U4RQC1
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

206403:YH65 RS01460
gene id: 206403:YH65_RS01460
uniprot id: A0A7U4RPW4
names: Function
names: Similarity
messages: Belongs to the APS kinase family.
messages: Catalyzes the synthesis of activated sulfate.

206403:YH65 RS00300
gene id: 206403:YH65_RS00300
uniprot id: A0A7U4RPU5
names: Similarity
messages: Belongs to the helicase family. RecQ subfamily.

206403:YH65 RS09970
gene id: 206403:YH65_RS09970
uniprot id: A0A7U4RRC2
names: Similarity
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.

206403:YH65 RS00315
gene id: 206403:YH65_RS00315
uniprot id: A0A7U4LZC9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Reduced FMN (FMNH(2)).

206403:YH65 RS09765
gene id: 206403:YH65_RS09765
uniprot id: A0A7U4M2F2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.
messages: Binds 2 iron ions per subunit.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

206403:YH65 RS02835
gene id: 206403:YH65_RS02835
uniprot id: A0A7U4M069
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HemJ family.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.
messages: Catalyzes the oxidation of protoporphyrinogen IX to protoporphyrin IX.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

206403:YH65 RS09875
gene id: 206403:YH65_RS09875
uniprot id: A0A7U4M2K2
names: Similarity
messages: Belongs to the UPF0102 family.

206403:YH65 RS02285
gene id: 206403:YH65_RS02285
uniprot id: A0A7U4RQ50
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gmhB family.
messages: Cytoplasm

206403:YH65 RS00110
gene id: 206403:YH65_RS00110
uniprot id: A0A7U4LZF4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

206403:YH65 RS01715
gene id: 206403:YH65_RS01715
uniprot id: A0A7U4RPY0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

206403:YH65 RS07880
gene id: 206403:YH65_RS07880
uniprot id: A0A7U4M1W8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

206403:YH65 RS05340
gene id: 206403:YH65_RS05340
uniprot id: A0A7U4M181
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

206403:YH65 RS04950
gene id: 206403:YH65_RS04950
uniprot id: A0A7U4M0X5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase Z family.
messages: Binds 2 Zn(2+) ions.
messages: Homodimer.
messages: Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA.

206403:YH65 RS08280
gene id: 206403:YH65_RS08280
uniprot id: A0A7U4M288
names: Similarity
messages: Belongs to the class-I fumarase family.

206403:YH65 RS00600
gene id: 206403:YH65_RS00600
uniprot id: A0A7U4LZK2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

206403:YH65 RS08575
gene id: 206403:YH65_RS08575
uniprot id: A0A7U4M257
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

206403:YH65 RS09045
gene id: 206403:YH65_RS09045
uniprot id: A0A7U4M286
names: Similarity
messages: Belongs to the pyruvate kinase family.

206403:YH65 RS03175
gene id: 206403:YH65_RS03175
uniprot id: A0A7U4M0D2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm

206403:YH65 RS02105
gene id: 206403:YH65_RS02105
uniprot id: A0A7U4LZZ3
names: Function
names: Similarity
messages: Belongs to the NadC/ModD family.
messages: Involved in the catabolism of quinolinic acid (QA).

206403:YH65 RS02880
gene id: 206403:YH65_RS02880
uniprot id: A0A7U4M083
names: Subcellular Location Annotation
messages: Membrane

206403:YH65 RS04205
gene id: 206403:YH65_RS04205
uniprot id: A0A7U4M0P2
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

206403:YH65 RS03600
gene id: 206403:YH65_RS03600
uniprot id: A0A7U4M0J5
names: Similarity
messages: Belongs to the GSP E family.

206403:YH65 RS09785
gene id: 206403:YH65_RS09785
uniprot id: A0A7U4M2G5
names: Subcellular Location Annotation
messages: Membrane

206403:YH65 RS04500
gene id: 206403:YH65_RS04500
uniprot id: A0A7U4M0P8
names: Function
names: Similarity
messages: Belongs to the QueH family.
messages: Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr).

206403:YH65 RS02495
gene id: 206403:YH65_RS02495
uniprot id: A0A7U4RQ15
names: Similarity
messages: Belongs to the helicase family. RecG subfamily.

206403:YH65 RS00060
gene id: 206403:YH65_RS00060
uniprot id: A0A7U4RPR6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

206403:YH65 RS07340
gene id: 206403:YH65_RS07340
uniprot id: A0A7U4M1N5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobD/CbiB family.
messages: Cell membrane
messages: Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

206403:YH65 RS04505
gene id: 206403:YH65_RS04505
uniprot id: A0A7U4M0T1
names: Function
messages: Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

206403:YH65 RS01925
gene id: 206403:YH65_RS01925
uniprot id: A0A7U4RQ43
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

206403:YH65 RS00030
gene id: 206403:YH65_RS00030
uniprot id: A0A7U4LZD1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NifU family.
messages: Binds 1 Fe cation per subunit.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: May be involved in the formation or repair of [Fe-S] clusters present in iron-sulfur proteins.

206403:YH65 RS02140
gene id: 206403:YH65_RS02140
uniprot id: A0A7U4RQ32
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

206403:YH65 RS04610
gene id: 206403:YH65_RS04610
uniprot id: A0A7U4M0V4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

206403:YH65 RS09315
gene id: 206403:YH65_RS09315
uniprot id: A0A7U4RR86
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

206403:YH65 RS10345
gene id: 206403:YH65_RS10345
uniprot id: A0A7U4M2M0
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

206403:YH65 RS01250
gene id: 206403:YH65_RS01250
uniprot id: A0A7U4LZM5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
messages: Cytoplasm

206403:YH65 RS06605
gene id: 206403:YH65_RS06605
uniprot id: A0A7U4M1E2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

206403:YH65 RS10090
gene id: 206403:YH65_RS10090
uniprot id: A0A7U4RRA0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

206403:YH65 RS01225
gene id: 206403:YH65_RS01225
uniprot id: A0A7U4RQ04
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

206403:YH65 RS03110
gene id: 206403:YH65_RS03110
uniprot id: A0A7U4RQB2
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

206403:YH65 RS08065
gene id: 206403:YH65_RS08065
uniprot id: A0A7U4RR27
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

206403:YH65 RS10635
gene id: 206403:YH65_RS10635
uniprot id: A0A7U4RRH9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

206403:YH65 RS06840
gene id: 206403:YH65_RS06840
uniprot id: A0A7U4M1H2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

206403:YH65 RS10105
gene id: 206403:YH65_RS10105
uniprot id: A0A7U4M2J2
names: Similarity
messages: Belongs to the polypeptide deformylase family.

206403:YH65 RS00010
gene id: 206403:YH65_RS00010
uniprot id: A0A7U4LZB7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

206403:YH65 RS10320
gene id: 206403:YH65_RS10320
uniprot id: A0A7U4RRF7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MoaC family.
messages: Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
messages: Homohexamer; trimer of dimers.

206403:YH65 RS02165
gene id: 206403:YH65_RS02165
uniprot id: A0A7U4M016
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseA family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

206403:YH65 RS10620
gene id: 206403:YH65_RS10620
uniprot id: A0A7U4M2R0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

206403:YH65 RS05050
gene id: 206403:YH65_RS05050
uniprot id: A0A7U4M105
names: Similarity
messages: Belongs to the LacAB/RpiB family.

206403:YH65 RS01470
gene id: 206403:YH65_RS01470
uniprot id: A0A7U4LZU7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inositol monophosphatase superfamily. CysQ family.
messages: Cell membrane
messages: Converts adenosine-3',5'-bisphosphate (PAP) to AMP.

206403:YH65 RS07205
gene id: 206403:YH65_RS07205
uniprot id: A0A7U4M1P4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

206403:YH65 RS00870
gene id: 206403:YH65_RS00870
uniprot id: A0A7U4LZN6
names: Similarity
messages: Belongs to the TrpF family.

206403:YH65 RS06770
gene id: 206403:YH65_RS06770
uniprot id: A0A7U4M1G7
names: Subcellular Location Annotation
messages: Membrane

206403:YH65 RS05820
gene id: 206403:YH65_RS05820
uniprot id: A0A7U4RQM0
names: Cofactor
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Binds 1 [3Fe-4S] cluster.
messages: Binds 1 [4Fe-4S] cluster.

206403:YH65 RS09085
gene id: 206403:YH65_RS09085
uniprot id: A0A7U4M262
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein bS6.

206403:YH65 RS05300
gene id: 206403:YH65_RS05300
uniprot id: A0A7U4M128
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

206403:YH65 RS10680
gene id: 206403:YH65_RS10680
uniprot id: A0A7U4RRG5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

206403:YH65 RS09060
gene id: 206403:YH65_RS09060
uniprot id: A0A7U4M2H9
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

206403:YH65 RS01945
gene id: 206403:YH65_RS01945
uniprot id: A0A7U4LZV8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

206403:YH65 RS03130
gene id: 206403:YH65_RS03130
uniprot id: A0A7U4M098
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

206403:YH65 RS00335
gene id: 206403:YH65_RS00335
uniprot id: A0A7U4RPQ9
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

206403:YH65 RS09370
gene id: 206403:YH65_RS09370
uniprot id: A0A7U4M2A3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

206403:YH65 RS08085
gene id: 206403:YH65_RS08085
uniprot id: A0A7U4RR06
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

206403:YH65 RS08790
gene id: 206403:YH65_RS08790
uniprot id: A0A7U4M2E0
names: Similarity
messages: Belongs to the ArsC family.

206403:YH65 RS07930
gene id: 206403:YH65_RS07930
uniprot id: A0A7U4RR32
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.
messages: Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.
messages: Cytoplasm
messages: Homodimer.

206403:YH65 RS00200
gene id: 206403:YH65_RS00200
uniprot id: A0A7U4LZE1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

206403:YH65 RS10565
gene id: 206403:YH65_RS10565
uniprot id: A0A7U4RRG1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

206403:YH65 RS08395
gene id: 206403:YH65_RS08395
uniprot id: A0A7U4M1Z4
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

206403:YH65 RS10885
gene id: 206403:YH65_RS10885
uniprot id: A0A7U4M2W1
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

206403:YH65 RS00825
gene id: 206403:YH65_RS00825
uniprot id: A0A7U4LZI0
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

206403:YH65 RS04835
gene id: 206403:YH65_RS04835
uniprot id: A0A7U4M0V6
names: Caution
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated Cas9 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9/crRNA/tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer; Cas9 is inactive in the absence of the 2 guide RNAs (gRNA). Cas9 recognizes the protospacer adjacent motif (PAM) in the CRISPR repeat sequences to help distinguish self versus nonself, as targets within the bacterial CRISPR locus do not have PAMs. PAM recognition is also required for catalytic activity.
messages: Has 2 endonuclease domains. The discontinuous RuvC-like domain cleaves the target DNA noncomplementary to crRNA while the HNH nuclease domain cleaves the target DNA complementary to crRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Binds crRNA and tracrRNA.

206403:YH65 RS09400
gene id: 206403:YH65_RS09400
uniprot id: A0A7U4M2A2
names: Similarity
messages: Belongs to the glutamine synthetase family.

206403:YH65 RS00495
gene id: 206403:YH65_RS00495
uniprot id: A0A7U4RPU7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

206403:YH65 RS02645
gene id: 206403:YH65_RS02645
uniprot id: A0A7U4M049
names: Similarity
messages: Belongs to the GARS family.

206403:YH65 RS10615
gene id: 206403:YH65_RS10615
uniprot id: A0A7U4M2Q6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

206403:YH65 RS00970
gene id: 206403:YH65_RS00970
uniprot id: A0A7U4RPT7
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

206403:YH65 RS04315
gene id: 206403:YH65_RS04315
uniprot id: A0A7U4RQI0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

206403:YH65 RS10685
gene id: 206403:YH65_RS10685
uniprot id: A0A7U4M2R1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

206403:YH65 RS00320
gene id: 206403:YH65_RS00320
uniprot id: A0A7U4LZD5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

206403:YH65 RS07215
gene id: 206403:YH65_RS07215
uniprot id: A0A7U4RQX6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. NspC subfamily.
messages: Cytoplasm
messages: Homodimer.

206403:YH65 RS01830
gene id: 206403:YH65_RS01830
uniprot id: A0A7U4LZV3
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

206403:YH65 RS08805
gene id: 206403:YH65_RS08805
uniprot id: A0A7U4RR68
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Acts as a global negative controlling element, employing Fe(2+) as a cofactor to bind the operator of the repressed genes.
messages: Belongs to the Fur family.
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Homodimer.

206403:YH65 RS01260
gene id: 206403:YH65_RS01260
uniprot id: A0A7U4LZS2
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Binds two Mg(2+) per subunit. The magnesium ions form salt bridges with both the protein and the DNA. Can also accept other divalent metal cations, such as Mn(2+) or Ca(2+).
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

206403:YH65 RS01070
gene id: 206403:YH65_RS01070
uniprot id: A0A7U4LZQ7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

206403:YH65 RS08970
gene id: 206403:YH65_RS08970
uniprot id: A0A7U4M250
names: Similarity
messages: Belongs to the peptidase C40 family.

206403:YH65 RS03730
gene id: 206403:YH65_RS03730
uniprot id: A0A7U4RQ78
names: Similarity
messages: Belongs to the UPF0763 family.

206403:YH65 RS06265
gene id: 206403:YH65_RS06265
uniprot id: A0A7U4M1D7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.
messages: Cell inner membrane
messages: Membrane
messages: Probable transporter of a GTP-driven Fe(2+) uptake system.

206403:YH65 RS08465
gene id: 206403:YH65_RS08465
uniprot id: A0A7U4M230
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

206403:YH65 RS02910
gene id: 206403:YH65_RS02910
uniprot id: A0A7U4RQA0
names: Similarity
messages: Belongs to the CFA/CMAS family.

206403:YH65 RS02120
gene id: 206403:YH65_RS02120
uniprot id: A0A7U4RQ37
names: Function
names: Similarity
messages: Belongs to the LpxC family.
messages: Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.

206403:YH65 RS06535
gene id: 206403:YH65_RS06535
uniprot id: A0A7U4M1E5
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

206403:YH65 RS02450
gene id: 206403:YH65_RS02450
uniprot id: A0A7U4M037
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

206403:YH65 RS02395
gene id: 206403:YH65_RS02395
uniprot id: A0A7U4RQ49
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm

206403:YH65 RS01330
gene id: 206403:YH65_RS01330
uniprot id: A0A7U4LZN8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Homodimer.
messages: Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate.

206403:YH65 RS05460
gene id: 206403:YH65_RS05460
uniprot id: A0A7U4M151
names: Similarity
messages: Belongs to the AAA ATPase family.

206403:YH65 RS06555
gene id: 206403:YH65_RS06555
uniprot id: A0A7U4M1D8
names: Subcellular Location Annotation
messages: Membrane

206403:YH65 RS10860
gene id: 206403:YH65_RS10860
uniprot id: A0A7U4RRH4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

206403:YH65 RS06245
gene id: 206403:YH65_RS06245
uniprot id: A0A7U4M1E3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ArsB family.
messages: Cell membrane
messages: Involved in arsenical resistance. Thought to form the channel of an arsenite pump.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

206403:YH65 RS01195
gene id: 206403:YH65_RS01195
uniprot id: A0A7U4LZR3
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

206403:YH65 RS07430
gene id: 206403:YH65_RS07430
uniprot id: A0A7U4RQZ2
names: Similarity
messages: Belongs to the YjdM family.

206403:YH65 RS05285
gene id: 206403:YH65_RS05285
uniprot id: A0A7U4M110
names: Similarity
messages: Belongs to the DNA polymerase type-Y family.

206403:YH65 RS10470
gene id: 206403:YH65_RS10470
uniprot id: A0A7U4RRG6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

206403:YH65 RS06915
gene id: 206403:YH65_RS06915
uniprot id: A0A7U4RQR4
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

206403:YH65 RS02685
gene id: 206403:YH65_RS02685
uniprot id: A0A7U4M052
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

206403:YH65 RS03150
gene id: 206403:YH65_RS03150
uniprot id: A0A7U4M0A7
names: Similarity
messages: Belongs to the RutC family.

206403:YH65 RS01075
gene id: 206403:YH65_RS01075
uniprot id: A0A7U4RPU1
names: Function
names: Similarity
messages: Belongs to the MqnA/MqnD family. MqnA subfamily.
messages: Catalyzes the dehydration of chorismate into 3-[(1-carboxyvinyl)oxy]benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2).

206403:YH65 RS10555
gene id: 206403:YH65_RS10555
uniprot id: A0A7U4M2S3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

206403:YH65 RS02200
gene id: 206403:YH65_RS02200
uniprot id: A0A7U4RQ45
names: Function
names: Similarity
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Homodimer.

206403:YH65 RS00860
gene id: 206403:YH65_RS00860
uniprot id: A0A7U4LZI6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

206403:YH65 RS02385
gene id: 206403:YH65_RS02385
uniprot id: A0A7U4M006
names: Similarity
messages: Belongs to the mannose-6-phosphate isomerase type 2 family.

206403:YH65 RS10845
gene id: 206403:YH65_RS10845
uniprot id: A0A7U4M2V2
names: Similarity
messages: Belongs to the SIS family. GutQ/KpsF subfamily.

206403:YH65 RS03545
gene id: 206403:YH65_RS03545
uniprot id: A0A7U4M0F0
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

206403:YH65 RS00655
gene id: 206403:YH65_RS00655
uniprot id: A0A7U4RPV7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

206403:YH65 RS05065
gene id: 206403:YH65_RS05065
uniprot id: A0A7U4RQH4
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

206403:YH65 RS03285
gene id: 206403:YH65_RS03285
uniprot id: A0A7U4M0B9
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

206403:YH65 RS00265
gene id: 206403:YH65_RS00265
uniprot id: A0A7U4LZD6
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanD family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
messages: Cytoplasm
messages: Heterooctamer of four alpha and four beta subunits.
messages: Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus.

206403:YH65 RS00580
gene id: 206403:YH65_RS00580
uniprot id: A0A7U4LZH7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein uL14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein uL14 (rplN).

206403:YH65 RS00640
gene id: 206403:YH65_RS00640
uniprot id: A0A7U4LZJ3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methylthiotransferase family. RimO subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein uS12.
messages: Cytoplasm

206403:YH65 RS05510
gene id: 206403:YH65_RS05510
uniprot id: A0A7U4RQN0
names: Subcellular Location Annotation
messages: Membrane

206403:YH65 RS02955
gene id: 206403:YH65_RS02955
uniprot id: A0A7U4RQ47
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

206403:YH65 RS05375
gene id: 206403:YH65_RS05375
uniprot id: A0A7U4M100
names: Similarity
messages: Belongs to the peptidase S41A family.

206403:YH65 RS01475
gene id: 206403:YH65_RS01475
uniprot id: A0A7U4LZQ5
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

206403:YH65 RS01800
gene id: 206403:YH65_RS01800
uniprot id: A0A7U4LZY8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the N7 position of a guanine in 16S rRNA.

206403:YH65 RS05310
gene id: 206403:YH65_RS05310
uniprot id: A0A7U4M0Y9
names: Similarity
messages: Belongs to the LOG family.

206403:YH65 RS03225
gene id: 206403:YH65_RS03225
uniprot id: A0A7U4RQ51
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

206403:YH65 RS08825
gene id: 206403:YH65_RS08825
uniprot id: A0A7U4M245
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.

206403:YH65 RS03625
gene id: 206403:YH65_RS03625
uniprot id: A0A7U4M0K4
names: Similarity
messages: Belongs to the IMPACT family.

206403:YH65 RS05385
gene id: 206403:YH65_RS05385
uniprot id: A0A7U4M142
names: Similarity
messages: Belongs to the ClpA/ClpB family.

206403:YH65 RS00105
gene id: 206403:YH65_RS00105
uniprot id: A0A7U4LZB3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Cell membrane
messages: Membrane

206403:YH65 RS05415
gene id: 206403:YH65_RS05415
uniprot id: A0A7U4M113
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LemA family.
messages: Membrane

206403:YH65 RS09230
gene id: 206403:YH65_RS09230
uniprot id: A0A7U4RR81
names: Function
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

206403:YH65 RS09265
gene id: 206403:YH65_RS09265
uniprot id: A0A7U4M291
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.

206403:YH65 RS00185
gene id: 206403:YH65_RS00185
uniprot id: A0A7U4LZC1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

206403:YH65 RS04030
gene id: 206403:YH65_RS04030
uniprot id: A0A7U4M0M5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

206403:YH65 RS05885
gene id: 206403:YH65_RS05885
uniprot id: A0A7U4M195
names: Function
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.
messages: Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate.

206403:YH65 RS03915
gene id: 206403:YH65_RS03915
uniprot id: A0A7U4RQ88
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

206403:YH65 RS01490
gene id: 206403:YH65_RS01490
uniprot id: A0A7U4RQ19
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

206403:YH65 RS00830
gene id: 206403:YH65_RS00830
uniprot id: A0A7U4LZM8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccA family.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

206403:YH65 RS10460
gene id: 206403:YH65_RS10460
uniprot id: A0A7U4M2N7
names: Similarity
messages: Belongs to the dGTPase family. Type 2 subfamily.

206403:YH65 RS07335
gene id: 206403:YH65_RS07335
uniprot id: A0A7U4RQT7
names: Function
names: Similarity
messages: Belongs to the CobB/CobQ family. CobQ subfamily.
messages: Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation.

206403:YH65 RS02925
gene id: 206403:YH65_RS02925
uniprot id: A0A7U4M081
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the selenophosphate synthase 1 family. Class I subfamily.
messages: Binds 1 Mg(2+) ion per monomer.
messages: Homodimer.
messages: Synthesizes selenophosphate from selenide and ATP.

206403:YH65 RS10760
gene id: 206403:YH65_RS10760
uniprot id: A0A7U4RRH0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

206403:YH65 RS03925
gene id: 206403:YH65_RS03925
uniprot id: A0A7U4M0I7
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

206403:YH65 RS01335
gene id: 206403:YH65_RS01335
uniprot id: A0A7U4LZN5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

206403:YH65 RS03955
gene id: 206403:YH65_RS03955
uniprot id: A0A7U4M0K1
names: Similarity
messages: Belongs to the peptidase S49 family.

206403:YH65 RS07810
gene id: 206403:YH65_RS07810
uniprot id: A0A7U4M1T0
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

206403:YH65 RS08275
gene id: 206403:YH65_RS08275
uniprot id: A0A7U4M1Y0
names: Similarity
messages: Belongs to the class-I fumarase family.

206403:YH65 RS07045
gene id: 206403:YH65_RS07045
uniprot id: A0A7U4M1M6
names: Similarity
messages: Belongs to the phD/YefM antitoxin family.

206403:YH65 RS03125
gene id: 206403:YH65_RS03125
uniprot id: A0A7U4M0A4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AB hydrolase superfamily. MetX family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.

206403:YH65 RS08050
gene id: 206403:YH65_RS08050
uniprot id: A0A7U4M379
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

206403:YH65 RS04865
gene id: 206403:YH65_RS04865
uniprot id: A0A7U4M0W5
names: Similarity
messages: Belongs to the HPS/KGPDC family. HPS subfamily.

206403:YH65 RS01235
gene id: 206403:YH65_RS01235
uniprot id: A0A7U4RPY9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

206403:YH65 RS03295
gene id: 206403:YH65_RS03295
uniprot id: A0A7U4RQ98
names: Cofactor
names: Similarity
messages: Belongs to the rubredoxin family.
messages: Binds 1 Fe(3+) ion per subunit.

206403:YH65 RS09985
gene id: 206403:YH65_RS09985
uniprot id: A0A7U4RRR1
names: Subcellular Location Annotation
messages: Membrane

206403:YH65 RS05205
gene id: 206403:YH65_RS05205
uniprot id: A0A7U4M120
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

206403:YH65 RS09990
gene id: 206403:YH65_RS09990
uniprot id: A0A7U4M2H5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

206403:YH65 RS10665
gene id: 206403:YH65_RS10665
uniprot id: A0A7U4M2T1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

206403:YH65 RS06505
gene id: 206403:YH65_RS06505
uniprot id: A0A7U4M1N4
names: Subcellular Location Annotation
messages: Membrane

206403:YH65 RS06520
gene id: 206403:YH65_RS06520
uniprot id: A0A7U4RQT6
names: Similarity
messages: Belongs to the thioredoxin family.

206403:YH65 RS08290
gene id: 206403:YH65_RS08290
uniprot id: A0A7U4RR53
names: Similarity
messages: Belongs to the LDH/MDH superfamily.

206403:YH65 RS06465
gene id: 206403:YH65_RS06465
uniprot id: A0A7U4RQT8
names: Similarity
messages: Belongs to the transposase IS21/IS408/IS1162 family.

206403:YH65 RS00390
gene id: 206403:YH65_RS00390
uniprot id: A0A7U4LZI3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OmpP1/FadL family.
messages: Cell outer membrane
messages: Membrane

206403:YH65 RS06460
gene id: 206403:YH65_RS06460
uniprot id: A0A7U4M1D4
names: Similarity
messages: Belongs to the IS21/IS1162 putative ATP-binding protein family.

206403:YH65 RS06440
gene id: 206403:YH65_RS06440
uniprot id: A0A7U4RQU8
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

206403:YH65 RS00910
gene id: 206403:YH65_RS00910
uniprot id: A0A7U4LZI9
names: Similarity
messages: Belongs to the ABC transporter superfamily.

206403:YH65 RS00800
gene id: 206403:YH65_RS00800
uniprot id: A0A7U4RPS8
names: Subcellular Location Annotation
messages: Membrane

206403:YH65 RS09735
gene id: 206403:YH65_RS09735
uniprot id: A0A7U4M2E5
names: Subcellular Location Annotation
messages: Membrane

206403:YH65 RS05900
gene id: 206403:YH65_RS05900
uniprot id: A0A7U4RQM5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell membrane
messages: Membrane

206403:YH65 RS04420
gene id: 206403:YH65_RS04420
uniprot id: A0A7U4M0N8
names: Similarity
messages: Belongs to the UPF0178 family.

206403:YH65 RS08945
gene id: 206403:YH65_RS08945
uniprot id: A0A7U4RR21
names: Function
names: Similarity
messages: Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage.
messages: Belongs to the Nudix hydrolase family. RppH subfamily.

206403:YH65 RS02380
gene id: 206403:YH65_RS02380
uniprot id: A0A7U4M1K3
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. GDP-mannose 4,6-dehydratase subfamily.
messages: Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6-deoxy-D-mannose.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

206403:YH65 RS02265
gene id: 206403:YH65_RS02265
uniprot id: A0A7U4M003
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SIS family. GmhA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate.
messages: Cytoplasm
messages: The reaction produces a racemic mixture of D-glycero-alpha-D-manno-heptose 7-phosphate and D-glycero-beta-D-manno-heptose 7-phosphate.

206403:YH65 RS01120
gene id: 206403:YH65_RS01120
uniprot id: A0A7U4RPY3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

206403:YH65 RS10890
gene id: 206403:YH65_RS10890
uniprot id: A0A7U4RRJ4
names: Similarity
messages: Belongs to the citrate synthase family.

206403:YH65 RS06820
gene id: 206403:YH65_RS06820
uniprot id: A0A7U4RQQ9
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

206403:YH65 RS09280
gene id: 206403:YH65_RS09280
uniprot id: A0A7U4M2A1
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

206403:YH65 RS02145
gene id: 206403:YH65_RS02145
uniprot id: A0A7U4M023
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

206403:YH65 RS09635
gene id: 206403:YH65_RS09635
uniprot id: A0A7U4RRA4
names: Subcellular Location Annotation
messages: Membrane

206403:YH65 RS10750
gene id: 206403:YH65_RS10750
uniprot id: A0A7U4RRE2
names: Similarity
messages: Belongs to the UPF0045 family.

206403:YH65 RS08965
gene id: 206403:YH65_RS08965
uniprot id: A0A7U4M279
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

206403:YH65 RS09465
gene id: 206403:YH65_RS09465
uniprot id: A0A7U4M2P4
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF2.
messages: Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.

206403:YH65 RS06085
gene id: 206403:YH65_RS06085
uniprot id: A0A7U4M190
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.

206403:YH65 RS10265
gene id: 206403:YH65_RS10265
uniprot id: A0A7U4M2L1
names: Caution
names: Function
names: Similarity
messages: Belongs to the MqnA/MqnD family. MqnD subfamily.
messages: Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

206403:YH65 RS00080
gene id: 206403:YH65_RS00080
uniprot id: A0A7U4LZB8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

206403:YH65 RS09645
gene id: 206403:YH65_RS09645
uniprot id: A0A7U4M2D6
names: Subcellular Location Annotation
messages: Membrane

206403:YH65 RS02360
gene id: 206403:YH65_RS02360
uniprot id: A0A7U4M034
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

206403:YH65 RS03360
gene id: 206403:YH65_RS03360
uniprot id: A0A7U4M0C5
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by GTP. Inhibited by UTP.
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

206403:YH65 RS00400
gene id: 206403:YH65_RS00400
uniprot id: A0A7U4RPV5
names: Cofactor
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. NagA family.
messages: Binds 1 divalent metal cation per subunit.

206403:YH65 RS02290
gene id: 206403:YH65_RS02290
uniprot id: A0A7U4M002
names: Similarity
messages: Belongs to the bacterial sugar transferase family.

206403:YH65 RS10350
gene id: 206403:YH65_RS10350
uniprot id: A0A7U4M2N0
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

206403:YH65 RS02130
gene id: 206403:YH65_RS02130
uniprot id: A0A7U4LZX7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. Homoserine kinase subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
messages: Cytoplasm

206403:YH65 RS02085
gene id: 206403:YH65_RS02085
uniprot id: A0A7U4M001
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

206403:YH65 RS09210
gene id: 206403:YH65_RS09210
uniprot id: A0A7U4M284
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YajC family.
messages: Membrane

206403:YH65 RS01210
gene id: 206403:YH65_RS01210
uniprot id: A0A7U4LZQ9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

206403:YH65 RS01570
gene id: 206403:YH65_RS01570
uniprot id: A0A7U4LZV0
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity.

206403:YH65 RS10855
gene id: 206403:YH65_RS10855
uniprot id: A0A7U4M2T4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

206403:YH65 RS04090
gene id: 206403:YH65_RS04090
uniprot id: A0A7U4M0J3
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

206403:YH65 RS02740
gene id: 206403:YH65_RS02740
uniprot id: A0A7U4M056
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

206403:YH65 RS06500
gene id: 206403:YH65_RS06500
uniprot id: A0A7U4M1D9
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane
messages: Membrane

206403:YH65 RS03230
gene id: 206403:YH65_RS03230
uniprot id: A0A7U4M0A9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

206403:YH65 RS03980
gene id: 206403:YH65_RS03980
uniprot id: A0A7U4M0I4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

206403:YH65 RS05805
gene id: 206403:YH65_RS05805
uniprot id: A0A7U4M184
names: Caution
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the thiamine-monophosphate kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate.

206403:YH65 RS06750
gene id: 206403:YH65_RS06750
uniprot id: A0A7U4RQS9
names: Similarity
messages: Belongs to the MEMO1 family.

206403:YH65 RS01170
gene id: 206403:YH65_RS01170
uniprot id: A0A7U4RPU4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

206403:YH65 RS03105
gene id: 206403:YH65_RS03105
uniprot id: A0A7U4M0B5
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

206403:YH65 RS06530
gene id: 206403:YH65_RS06530
uniprot id: A0A7U4M1E0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

206403:YH65 RS09095
gene id: 206403:YH65_RS09095
uniprot id: A0A7U4RR79
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Lacks the C-terminal regulatory region which is replaced by HisZ.

206403:YH65 RS00160
gene id: 206403:YH65_RS00160
uniprot id: A0A7U4LZC3
names: Similarity
messages: Belongs to the GSP E family.

206403:YH65 RS08130
gene id: 206403:YH65_RS08130
uniprot id: A0A7U4M1W5
names: Function
names: Similarity
messages: Belongs to the PemK/MazF family.
messages: Toxic component of a type II toxin-antitoxin (TA) system.

206403:YH65 RS00905
gene id: 206403:YH65_RS00905
uniprot id: A0A7U4LZN3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

206403:YH65 RS07905
gene id: 206403:YH65_RS07905
uniprot id: A0A7U4M1T8
names: Similarity
messages: Belongs to the UbiD family.

206403:YH65 RS08915
gene id: 206403:YH65_RS08915
uniprot id: A0A7U4M241
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.

206403:YH65 RS00500
gene id: 206403:YH65_RS00500
uniprot id: A0A7U4LZG7
names: Subcellular Location Annotation
messages: Membrane

206403:YH65 RS02355
gene id: 206403:YH65_RS02355
uniprot id: A0A7U4M013
names: Similarity
messages: Belongs to the ABC transporter superfamily.

206403:YH65 RS01390
gene id: 206403:YH65_RS01390
uniprot id: A0A7U4LZT7
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

206403:YH65 RS05875
gene id: 206403:YH65_RS05875
uniprot id: A0A7U4M157
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

206403:YH65 RS00415
gene id: 206403:YH65_RS00415
uniprot id: A0A7U4LZE4
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.

206403:YH65 RS02405
gene id: 206403:YH65_RS02405
uniprot id: A0A7U4RQ10
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

206403:YH65 RS04450
gene id: 206403:YH65_RS04450
uniprot id: A0A7U4M0P1
names: Similarity
messages: Belongs to the UPRTase family.

206403:YH65 RS09685
gene id: 206403:YH65_RS09685
uniprot id: A0A7U4M2F7
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

206403:YH65 RS06045
gene id: 206403:YH65_RS06045
uniprot id: A0A7U4RQQ8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DHBP synthase family.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Homodimer.
messages: In the C-terminal section; belongs to the GTP cyclohydrolase II family.
messages: In the N-terminal section; belongs to the DHBP synthase family.

206403:YH65 RS05255
gene id: 206403:YH65_RS05255
uniprot id: A0A7U4M112
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

206403:YH65 RS10610
gene id: 206403:YH65_RS10610
uniprot id: A0A7U4M2Q1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

206403:YH65 RS10580
gene id: 206403:YH65_RS10580
uniprot id: A0A7U4M2Q9
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

206403:YH65 RS06615
gene id: 206403:YH65_RS06615
uniprot id: A0A7U4M1F0
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

206403:YH65 RS03240
gene id: 206403:YH65_RS03240
uniprot id: A0A7U4M0C8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

206403:YH65 RS02855
gene id: 206403:YH65_RS02855
uniprot id: A0A7U4M0A1
names: Subcellular Location Annotation
messages: Membrane

206403:YH65 RS06975
gene id: 206403:YH65_RS06975
uniprot id: A0A7U4M1I7
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

206403:YH65 RS03440
gene id: 206403:YH65_RS03440
uniprot id: A0A7U4M0D9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.

206403:YH65 RS10195
gene id: 206403:YH65_RS10195
uniprot id: A0A7U4M2K5
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

206403:YH65 RS08285
gene id: 206403:YH65_RS08285
uniprot id: A0A7U4M224
names: Similarity
messages: Belongs to the LDH/MDH superfamily.

206403:YH65 RS08090
gene id: 206403:YH65_RS08090
uniprot id: A0A7U4M1W3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Cytoplasm
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

206403:YH65 RS06480
gene id: 206403:YH65_RS06480
uniprot id: A0A7U4M1C6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

206403:YH65 RS00385
gene id: 206403:YH65_RS00385
uniprot id: A0A7U4LZE5
names: Similarity
messages: Belongs to the AB hydrolase superfamily. Lipase family.

206403:YH65 RS09385
gene id: 206403:YH65_RS09385
uniprot id: A0A7U4RRA6
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

206403:YH65 RS00190
gene id: 206403:YH65_RS00190
uniprot id: A0A7U4LZF7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

206403:YH65 RS02270
gene id: 206403:YH65_RS02270
uniprot id: A0A7U4M026
names: Subcellular Location Annotation
messages: Membrane

206403:YH65 RS07245
gene id: 206403:YH65_RS07245
uniprot id: A0A7U4M1Q4
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

206403:YH65 RS05035
gene id: 206403:YH65_RS05035
uniprot id: A0A7U4M0Y5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

206403:YH65 RS07990
gene id: 206403:YH65_RS07990
uniprot id: A0A7U4M1X7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

206403:YH65 RS10925
gene id: 206403:YH65_RS10925
uniprot id: A0A7U4RRJ3
names: Subcellular Location Annotation
messages: Membrane

206403:YH65 RS02225
gene id: 206403:YH65_RS02225
uniprot id: A0A7U4M036
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

206403:YH65 RS05200
gene id: 206403:YH65_RS05200
uniprot id: A0A7U4RQL1
names: Similarity
messages: Belongs to the YggT family.

206403:YH65 RS01280
gene id: 206403:YH65_RS01280
uniprot id: A0A7U4RPV2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

206403:YH65 RS07255
gene id: 206403:YH65_RS07255
uniprot id: A0A7U4M1M1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase A chain family.
messages: Cell membrane
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

206403:YH65 RS06220
gene id: 206403:YH65_RS06220
uniprot id: A0A7U4M1D2
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

206403:YH65 RS03825
gene id: 206403:YH65_RS03825
uniprot id: A0A7U4RQ84
names: Subcellular Location Annotation
messages: Membrane

206403:YH65 RS03155
gene id: 206403:YH65_RS03155
uniprot id: A0A7U4RQ60
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

206403:YH65 RS10600
gene id: 206403:YH65_RS10600
uniprot id: A0A7U4M2Q2
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

206403:YH65 RS05625
gene id: 206403:YH65_RS05625
uniprot id: A0A7U4M170
names: Subcellular Location Annotation
messages: Membrane

206403:YH65 RS05765
gene id: 206403:YH65_RS05765
uniprot id: A0A7U4RQR2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

206403:YH65 RS01190
gene id: 206403:YH65_RS01190
uniprot id: A0A7U4LZQ4
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

206403:YH65 RS01875
gene id: 206403:YH65_RS01875
uniprot id: A0A7U4RQ17
names: Subcellular Location Annotation
messages: Membrane

206403:YH65 RS08385
gene id: 206403:YH65_RS08385
uniprot id: A0A7U4RR55
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Monomer.

206403:YH65 RS00095
gene id: 206403:YH65_RS00095
uniprot id: A0A7U4LZC4
names: Subcellular Location Annotation
messages: Membrane

206403:YH65 RS02980
gene id: 206403:YH65_RS02980
uniprot id: A0A7U4M099
names: Domain
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 dependent methionine synthase family.
messages: Catalyzes the transfer of a methyl group from methyl-cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
messages: Modular enzyme with four functionally distinct domains. The isolated Hcy-binding domain catalyzes methyl transfer from free methylcobalamin to homocysteine. The Hcy-binding domain in association with the pterin-binding domain catalyzes the methylation of cob(I)alamin by methyltetrahydrofolate and the methylation of homocysteine. The B12-binding domain binds the cofactor. The AdoMet activation domain binds S-adenosyl-L-methionine. Under aerobic conditions cob(I)alamin can be converted to inactive cob(II)alamin. Reductive methylation by S-adenosyl-L-methionine and flavodoxin regenerates methylcobalamin.

206403:YH65 RS01720
gene id: 206403:YH65_RS01720
uniprot id: A0A7U4LZW3
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvB family.
messages: Cytoplasm
messages: Has 3 domains, the large (RuvB-L) and small ATPase (RuvB-S) domains and the C-terminal head (RuvB-H) domain. The head domain binds DNA, while the ATPase domains jointly bind ATP, ADP or are empty depending on the state of the subunit in the translocation cycle. During a single DNA translocation step the structure of each domain remains the same, but their relative positions change.
messages: Homohexamer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time. Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange. Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration. The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration. Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.

206403:YH65 RS08540
gene id: 206403:YH65_RS08540
uniprot id: A0A7U4M211
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.
messages: In the C-terminal section; belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: In the N-terminal section; belongs to the MIP18 family.

206403:YH65 RS07900
gene id: 206403:YH65_RS07900
uniprot id: A0A7U4RQZ3
names: Similarity
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.

206403:YH65 RS10115
gene id: 206403:YH65_RS10115
uniprot id: A0A7U4M2J8
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

206403:YH65 RS08410
gene id: 206403:YH65_RS08410
uniprot id: A0A7U4RR45
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm

206403:YH65 RS08265
gene id: 206403:YH65_RS08265
uniprot id: A0A7U4M1Y6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

206403:YH65 RS08960
gene id: 206403:YH65_RS08960
uniprot id: A0A7U4M265
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell membrane
messages: Forms a complex with TatA.
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.

206403:YH65 RS04920
gene id: 206403:YH65_RS04920
uniprot id: A0A7U4M0V9
names: Similarity
messages: Belongs to the AdoMet synthase family.

206403:YH65 RS09395
gene id: 206403:YH65_RS09395
uniprot id: A0A7U4M2A4
names: Similarity
messages: Belongs to the PHP hydrolase family. HisK subfamily.

206403:YH65 RS10015
gene id: 206403:YH65_RS10015
uniprot id: A0A7U4M2I3
names: Subcellular Location Annotation
names: Subunit
messages: Membrane
messages: The main subunits of complex b-c1 are: cytochrome b, cytochrome c1 and the Rieske protein.

206403:YH65 RS05530
gene id: 206403:YH65_RS05530
uniprot id: A0A7U4RQN1
names: Subcellular Location Annotation
messages: Membrane

206403:YH65 RS03220
gene id: 206403:YH65_RS03220
uniprot id: A0A7U4M0F3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

206403:YH65 RS10740
gene id: 206403:YH65_RS10740
uniprot id: A0A7U4RRI5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

206403:YH65 RS05565
gene id: 206403:YH65_RS05565
uniprot id: A0A7U4M153
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DEAD box helicase family. RhlE subfamily.
messages: Cytoplasm
messages: DEAD-box RNA helicase involved in ribosome assembly. Has RNA-dependent ATPase activity and unwinds double-stranded RNA.

206403:YH65 RS05690
gene id: 206403:YH65_RS05690
uniprot id: A0A7U4RQP0
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

206403:YH65 RS09595
gene id: 206403:YH65_RS09595
uniprot id: A0A7U4M2C5
names: Similarity
messages: Belongs to the Ahb/Nir family.

206403:YH65 RS01465
gene id: 206403:YH65_RS01465
uniprot id: A0A7U4LZT6
names: Function
names: Similarity
messages: Belongs to the APS kinase family.
messages: Catalyzes the synthesis of activated sulfate.

206403:YH65 RS01755
gene id: 206403:YH65_RS01755
uniprot id: A0A7U4RQ34
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Homooctamer.

206403:YH65 RS03720
gene id: 206403:YH65_RS03720
uniprot id: A0A7U4RQC2
names: Function
names: Similarity
messages: Belongs to the SELO family.
messages: Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr or Tyr residues of target proteins (AMPylation).

206403:YH65 RS05695
gene id: 206403:YH65_RS05695
uniprot id: A0A7U4M133
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

206403:YH65 RS07140
gene id: 206403:YH65_RS07140
uniprot id: A0A7U4RQX2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the etk/wzc family.
messages: Cell inner membrane
messages: Membrane

206403:YH65 RS06410
gene id: 206403:YH65_RS06410
uniprot id: A0A7U4M1C7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0718 family.
messages: Cell membrane
messages: Membrane

206403:YH65 RS10870
gene id: 206403:YH65_RS10870
uniprot id: A0A7U4M2T8
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.

206403:YH65 RS04480
gene id: 206403:YH65_RS04480
uniprot id: A0A7U4M0R9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

206403:YH65 RS00440
gene id: 206403:YH65_RS00440
uniprot id: A0A7U4LZH0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 3 family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

206403:YH65 RS10170
gene id: 206403:YH65_RS10170
uniprot id: A0A7U4RRA5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Cell wall formation.
messages: Cytoplasm

206403:YH65 RS03555
gene id: 206403:YH65_RS03555
uniprot id: A0A7U4M0G0
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: Allosterically activated by HslU binding.
messages: Belongs to the peptidase T1B family. HslV subfamily.
messages: Cytoplasm
messages: Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.

206403:YH65 RS06515
gene id: 206403:YH65_RS06515
uniprot id: A0A7U4RQV2
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

206403:YH65 RS07185
gene id: 206403:YH65_RS07185
uniprot id: A0A7U4M1L3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
messages: Binds 1 potassium ion per subunit.
messages: Cytoplasm
messages: Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

206403:YH65 RS04885
gene id: 206403:YH65_RS04885
uniprot id: A0A7U4RQI8
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

206403:YH65 RS00635
gene id: 206403:YH65_RS00635
uniprot id: A0A7U4LZK7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.

206403:YH65 RS00590
gene id: 206403:YH65_RS00590
uniprot id: A0A7U4LZG4
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

206403:YH65 RS06880
gene id: 206403:YH65_RS06880
uniprot id: A0A7U4RQX3
names: Similarity
messages: Belongs to the nitroreductase family.

206403:YH65 RS04280
gene id: 206403:YH65_RS04280
uniprot id: A0A7U4M0N3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Nitrate/nitrite porter (TC 2.A.1.8) family.
messages: Membrane

206403:YH65 RS05005
gene id: 206403:YH65_RS05005
uniprot id: A0A7U4M0Y3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M17 family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm
messages: Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.

206403:YH65 RS01320
gene id: 206403:YH65_RS01320
uniprot id: A0A7U4RPZ3
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

206403:YH65 RS05890
gene id: 206403:YH65_RS05890
uniprot id: A0A7U4RQK2
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fluoride channel Fluc/FEX (TC 1.A.43) family.
messages: Cell membrane
messages: Fluoride-specific ion channel. Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane
messages: Na(+) is not transported, but it plays an essential structural role and its presence is essential for fluoride channel function.

206403:YH65 RS08525
gene id: 206403:YH65_RS08525
uniprot id: A0A7U4M234
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 independent methionine synthase family.
messages: Binds 1 zinc ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine resulting in methionine formation.

206403:YH65 RS09030
gene id: 206403:YH65_RS09030
uniprot id: A0A7U4M261
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterioferritin family.
messages: Cytoplasm
messages: Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex.

206403:YH65 RS03250
gene id: 206403:YH65_RS03250
uniprot id: A0A7U4M0B3
names: Similarity
messages: Belongs to the MEMO1 family.

206403:YH65 RS03370
gene id: 206403:YH65_RS03370
uniprot id: A0A7U4M0C7
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

206403:YH65 RS03450
gene id: 206403:YH65_RS03450
uniprot id: A0A7U4RQA7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
messages: Could methylate the ribose at the nucleotide 34 wobble position in tRNA.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

206403:YH65 RS08795
gene id: 206403:YH65_RS08795
uniprot id: A0A7U4M281
names: Similarity
messages: Belongs to the GSP E family.

206403:YH65 RS00850
gene id: 206403:YH65_RS00850
uniprot id: A0A7U4LZJ5
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArgJ family.
messages: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.
messages: Cytoplasm
messages: Heterotetramer of two alpha and two beta chains.
messages: Some bacteria possess a monofunctional ArgJ, i.e., capable of catalyzing only the fifth step of the arginine biosynthetic pathway.

206403:YH65 RS03115
gene id: 206403:YH65_RS03115
uniprot id: A0A7U4RQ94
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

206403:YH65 RS10340
gene id: 206403:YH65_RS10340
uniprot id: A0A7U4RRE4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

206403:YH65 RS09530
gene id: 206403:YH65_RS09530
uniprot id: A0A7U4M2E1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NapD family.
messages: Chaperone for NapA, the catalytic subunit of the periplasmic nitrate reductase. It binds directly and specifically to the twin-arginine signal peptide of NapA, preventing premature interaction with the Tat translocase and premature export.
messages: Cytoplasm
messages: Interacts with the cytoplasmic NapA precursor.

206403:YH65 RS04860
gene id: 206403:YH65_RS04860
uniprot id: A0A7U4M0T5
names: Similarity
messages: Belongs to the SIS family. PHI subfamily.

206403:YH65 RS02965
gene id: 206403:YH65_RS02965
uniprot id: A0A7U4M096
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
messages: Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
messages: Homotrimer.

206403:YH65 RS02675
gene id: 206403:YH65_RS02675
uniprot id: A0A7U4RQ25
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Membrane

206403:YH65 RS05365
gene id: 206403:YH65_RS05365
uniprot id: A0A7U4M118
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PurS family.
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

206403:YH65 RS02205
gene id: 206403:YH65_RS02205
uniprot id: A0A7U4LZZ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

206403:YH65 RS01355
gene id: 206403:YH65_RS01355
uniprot id: A0A7U4LZT2
names: Function
names: Similarity
messages: Belongs to the 2H phosphoesterase superfamily. ThpR family.
messages: Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'-phosphomonoester.

206403:YH65 RS03840
gene id: 206403:YH65_RS03840
uniprot id: A0A7U4RRN3
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruD family.
messages: Responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs.

206403:YH65 RS03485
gene id: 206403:YH65_RS03485
uniprot id: A0A7U4M0E3
names: Similarity
messages: Belongs to the TrpC family.

206403:YH65 RS00450
gene id: 206403:YH65_RS00450
uniprot id: A0A7U4LZF9
names: Function
names: Similarity
messages: Belongs to the complex I 30 kDa subunit family.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.

206403:YH65 RS01485
gene id: 206403:YH65_RS01485
uniprot id: A0A7U4LZS5
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

206403:YH65 RS01480
gene id: 206403:YH65_RS01480
uniprot id: A0A7U4LZU1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
messages: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.
messages: Homodimer.

206403:YH65 RS10690
gene id: 206403:YH65_RS10690
uniprot id: A0A7U4M2R5
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

206403:YH65 RS09250
gene id: 206403:YH65_RS09250
uniprot id: A0A7U4RR92
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

206403:YH65 RS01905
gene id: 206403:YH65_RS01905
uniprot id: A0A7U4LZZ0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

206403:YH65 RS01185
gene id: 206403:YH65_RS01185
uniprot id: A0A7U4RPU9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.

206403:YH65 RS05925
gene id: 206403:YH65_RS05925
uniprot id: A0A7U4M185
names: Function
names: Similarity
names: Subunit
messages: Belongs to the polyphosphate kinase 2 (PPK2) family. Class I subfamily.
messages: Homotetramer.
messages: Uses inorganic polyphosphate (polyP) as a donor to convert GDP to GTP or ADP to ATP.

206403:YH65 RS06910
gene id: 206403:YH65_RS06910
uniprot id: A0A7U4M1L4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

206403:YH65 RS05605
gene id: 206403:YH65_RS05605
uniprot id: A0A7U4M124
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

206403:YH65 RS05650
gene id: 206403:YH65_RS05650
uniprot id: A0A7U4M144
names: Subcellular Location Annotation
messages: Membrane

206403:YH65 RS04225
gene id: 206403:YH65_RS04225
uniprot id: A0A7U4RQH2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Cell inner membrane
messages: Membrane

206403:YH65 RS00965
gene id: 206403:YH65_RS00965
uniprot id: A0A7U4LZP7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. Biotin synthase family.
messages: Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

206403:YH65 RS07565
gene id: 206403:YH65_RS07565
uniprot id: A0A7U4M1Q8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurJ/MviN family.
messages: Cell membrane
messages: Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

206403:YH65 RS04970
gene id: 206403:YH65_RS04970
uniprot id: A0A7U4RQE6
names: Cofactor
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.
messages: Probably binds two magnesium or manganese ions per subunit.

206403:YH65 RS01000
gene id: 206403:YH65_RS01000
uniprot id: A0A7U4LZP5
names: Similarity
messages: Belongs to the ABC transporter superfamily.

206403:YH65 RS07600
gene id: 206403:YH65_RS07600
uniprot id: A0A7U4M1Q7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
messages: Cell membrane
messages: Monomer.

206403:YH65 RS08350
gene id: 206403:YH65_RS08350
uniprot id: A0A7U4M205
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

206403:YH65 RS08295
gene id: 206403:YH65_RS08295
uniprot id: A0A7U4RR37
names: Cofactor
names: Similarity
messages: Belongs to the monomeric-type IDH family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

206403:YH65 RS07790
gene id: 206403:YH65_RS07790
uniprot id: A0A7U4M1V8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

206403:YH65 RS03045
gene id: 206403:YH65_RS03045
uniprot id: A0A7U4M0A0
names: Similarity
messages: Belongs to the ACC deaminase/D-cysteine desulfhydrase family.

206403:YH65 RS00305
gene id: 206403:YH65_RS00305
uniprot id: A0A7U4RPT6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

206403:YH65 RS06115
gene id: 206403:YH65_RS06115
uniprot id: A0A7U4M182
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

206403:YH65 RS02995
gene id: 206403:YH65_RS02995
uniprot id: A0A7U4M085
names: Similarity
messages: Belongs to the ATP:guanido phosphotransferase family.

206403:YH65 RS04080
gene id: 206403:YH65_RS04080
uniprot id: A0A7U4M0J4
names: Cofactor
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.
messages: Binds 1 [4Fe-4S] cluster per subunit.

206403:YH65 RS10175
gene id: 206403:YH65_RS10175
uniprot id: A0A7U4M2K7
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

206403:YH65 RS01580
gene id: 206403:YH65_RS01580
uniprot id: A0A7U4RRG8
names: Subcellular Location Annotation
messages: Membrane

206403:YH65 RS07985
gene id: 206403:YH65_RS07985
uniprot id: A0A7U4M1U9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.
messages: Cell membrane
messages: Self-interacts. Interacts with FtsZ.

206403:YH65 RS03605
gene id: 206403:YH65_RS03605
uniprot id: A0A7U4M0F5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Membrane

206403:YH65 RS00380
gene id: 206403:YH65_RS00380
uniprot id: A0A7U4LZG9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the AP endonuclease 2 family.
messages: Binds 3 Zn(2+) ions.
messages: Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate.

206403:YH65 RS02480
gene id: 206403:YH65_RS02480
uniprot id: A0A7U4RQ54
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

206403:YH65 RS00715
gene id: 206403:YH65_RS00715
uniprot id: A0A7U4LZK1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

206403:YH65 RS06305
gene id: 206403:YH65_RS06305
uniprot id: A0A7U4M1E1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

206403:YH65 RS03180
gene id: 206403:YH65_RS03180
uniprot id: A0A7U4M0C2
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

206403:YH65 RS07640
gene id: 206403:YH65_RS07640
uniprot id: A0A7U4M1R2
names: Similarity
messages: Belongs to the outer membrane porin (Opr) (TC 1.B.25) family.

206403:YH65 RS02440
gene id: 206403:YH65_RS02440
uniprot id: A0A7U4M025
names: Function
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.
messages: Provides the (R)-glutamate required for cell wall biosynthesis.

206403:YH65 RS07120
gene id: 206403:YH65_RS07120
uniprot id: A0A7U4M1K3
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. GDP-mannose 4,6-dehydratase subfamily.
messages: Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6-deoxy-D-mannose.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

206403:YH65 RS08910
gene id: 206403:YH65_RS08910
uniprot id: A0A7U4M238
names: Similarity
messages: Belongs to the TlyA family.

206403:YH65 RS04620
gene id: 206403:YH65_RS04620
uniprot id: A0A7U4M0R1
names: Function
names: Similarity
messages: Belongs to the anhydro-N-acetylmuramic acid kinase family.
messages: Catalyzes the specific phosphorylation of 1,6-anhydro-N-acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling.

206403:YH65 RS01700
gene id: 206403:YH65_RS01700
uniprot id: A0A7U4LZX1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell membrane

206403:YH65 RS08770
gene id: 206403:YH65_RS08770
uniprot id: A0A7U4M242
names: Similarity
names: Subunit
messages: Belongs to the peptidase M20A family. DapE subfamily.
messages: Homodimer.

206403:YH65 RS01405
gene id: 206403:YH65_RS01405
uniprot id: A0A7U4LZR7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

206403:YH65 RS05600
gene id: 206403:YH65_RS05600
uniprot id: A0A7U4M344
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

206403:YH65 RS00565
gene id: 206403:YH65_RS00565
uniprot id: A0A7U4LZI2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Forms a complex with TatC.
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.

206403:YH65 RS05315
gene id: 206403:YH65_RS05315
uniprot id: A0A7U4RQJ0
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by ADP and other diphosphonucleosides, and allosterically inhibited by phosphoenolpyruvate.
messages: Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Prokaryotic clade 'B1' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

206403:YH65 RS06495
gene id: 206403:YH65_RS06495
uniprot id: A0A7U4M1H1
names: Similarity
messages: Belongs to the DEAD box helicase family.

206403:YH65 RS09475
gene id: 206403:YH65_RS09475
uniprot id: A0A7U4RRA7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

206403:YH65 RS09235
gene id: 206403:YH65_RS09235
uniprot id: A0A7U4M287
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

206403:YH65 RS01900
gene id: 206403:YH65_RS01900
uniprot id: A0A7U4LZY1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

206403:YH65 RS07455
gene id: 206403:YH65_RS07455
uniprot id: A0A7U4M1N9
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

206403:YH65 RS01205
gene id: 206403:YH65_RS01205
uniprot id: A0A7U4LZM2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

206403:YH65 RS05180
gene id: 206403:YH65_RS05180
uniprot id: A0A7U4RQK8
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FBPase class 1 family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

206403:YH65 RS06995
gene id: 206403:YH65_RS06995
uniprot id: A0A7U4RQW9
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

206403:YH65 RS00155
gene id: 206403:YH65_RS00155
uniprot id: A0A7U4RPQ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial secretin family. GSP D subfamily.
messages: Cell outer membrane

206403:YH65 RS02475
gene id: 206403:YH65_RS02475
uniprot id: A0A7U4M017
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

206403:YH65 RS10570
gene id: 206403:YH65_RS10570
uniprot id: A0A7U4M2P3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

206403:YH65 RS00050
gene id: 206403:YH65_RS00050
uniprot id: A0A7U4LZA8
names: Similarity
messages: Belongs to the Nth/MutY family.

206403:YH65 RS08550
gene id: 206403:YH65_RS08550
uniprot id: A0A7U4M222
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

206403:YH65 RS03210
gene id: 206403:YH65_RS03210
uniprot id: A0A7U4M0A6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase delta chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

206403:YH65 RS10010
gene id: 206403:YH65_RS10010
uniprot id: A0A7U4RR94
names: Subcellular Location Annotation
messages: Membrane

206403:YH65 RS09260
gene id: 206403:YH65_RS09260
uniprot id: A0A7U4RR42
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

206403:YH65 RS00675
gene id: 206403:YH65_RS00675
uniprot id: A0A7U4RPV3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

206403:YH65 RS02095
gene id: 206403:YH65_RS02095
uniprot id: A0A7U4LZY3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsY family.
messages: Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
messages: Cell membrane
messages: Probably interacts with PlsX.

206403:YH65 RS09215
gene id: 206403:YH65_RS09215
uniprot id: A0A7U4M2L7
names: Subcellular Location Annotation
messages: Membrane

206403:YH65 RS03050
gene id: 206403:YH65_RS03050
uniprot id: A0A7U4M0A8
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

206403:YH65 RS02705
gene id: 206403:YH65_RS02705
uniprot id: A0A7U4M055
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

206403:YH65 RS05055
gene id: 206403:YH65_RS05055
uniprot id: A0A7U4RQF1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Cell membrane
messages: Membrane

206403:YH65 RS00490
gene id: 206403:YH65_RS00490
uniprot id: A0A7U4RPV9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 6 family.
messages: Cell membrane
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

206403:YH65 RS05305
gene id: 206403:YH65_RS05305
uniprot id: A0A7U4RQG8
names: Subcellular Location Annotation
messages: Membrane

206403:YH65 RS09140
gene id: 206403:YH65_RS09140
uniprot id: A0A7U4M2J6
names: Cofactor
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Binds 1 [3Fe-4S] cluster.
messages: Binds 1 [4Fe-4S] cluster.

206403:YH65 RS03160
gene id: 206403:YH65_RS03160
uniprot id: A0A7U4M0B0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

206403:YH65 RS10695
gene id: 206403:YH65_RS10695
uniprot id: A0A7U4M2S0
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

206403:YH65 RS09125
gene id: 206403:YH65_RS09125
uniprot id: A0A7U4M296
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA mismatch repair MutS family. MutS2 subfamily.
messages: Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity.
messages: Homodimer.

206403:YH65 RS01860
gene id: 206403:YH65_RS01860
uniprot id: A0A7U4LZU8
names: Similarity
messages: Belongs to the GSP E family.

206403:YH65 RS02220
gene id: 206403:YH65_RS02220
uniprot id: A0A7U4RQ40
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

206403:YH65 RS04470
gene id: 206403:YH65_RS04470
uniprot id: A0A7U4M0S9
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

206403:YH65 RS05155
gene id: 206403:YH65_RS05155
uniprot id: A0A7U4M109
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

206403:YH65 RS07895
gene id: 206403:YH65_RS07895
uniprot id: A0A7U4M1T9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Acts as a global negative controlling element, employing Fe(2+) as a cofactor to bind the operator of the repressed genes.
messages: Belongs to the Fur family.
messages: Binds 1 zinc ion per subunit.
messages: Homodimer.

206403:YH65 RS09155
gene id: 206403:YH65_RS09155
uniprot id: A0A7U4RR75
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

206403:YH65 RS02150
gene id: 206403:YH65_RS02150
uniprot id: A0A7U4RPZ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

206403:YH65 RS10650
gene id: 206403:YH65_RS10650
uniprot id: A0A7U4M2Q4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

206403:YH65 RS00180
gene id: 206403:YH65_RS00180
uniprot id: A0A7U4LZD7
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

206403:YH65 RS00290
gene id: 206403:YH65_RS00290
uniprot id: A0A7U4LZG5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
messages: Membrane

206403:YH65 RS01750
gene id: 206403:YH65_RS01750
uniprot id: A0A7U4LZV5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm

206403:YH65 RS09850
gene id: 206403:YH65_RS09850
uniprot id: A0A7U4RRB5
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

206403:YH65 RS04015
gene id: 206403:YH65_RS04015
uniprot id: A0A7U4M0J1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

206403:YH65 RS07165
gene id: 206403:YH65_RS07165
uniprot id: A0A7U4M1P1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FGAMS family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

206403:YH65 RS07705
gene id: 206403:YH65_RS07705
uniprot id: A0A7U4M1S7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

206403:YH65 RS08010
gene id: 206403:YH65_RS08010
uniprot id: A0A7U4M264
names: Function
names: Similarity
messages: Belongs to the Ap4A hydrolase family.
messages: Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP.

206403:YH65 RS09310
gene id: 206403:YH65_RS09310
uniprot id: A0A7U4RRA1
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

206403:YH65 RS02430
gene id: 206403:YH65_RS02430
uniprot id: A0A7U4M040
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

206403:YH65 RS03935
gene id: 206403:YH65_RS03935
uniprot id: A0A7U4M0I9
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

206403:YH65 RS03330
gene id: 206403:YH65_RS03330
uniprot id: A0A7U4M0C1
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

206403:YH65 RS04915
gene id: 206403:YH65_RS04915
uniprot id: A0A7U4M0Y2
names: Cofactor
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

206403:YH65 RS09365
gene id: 206403:YH65_RS09365
uniprot id: A0A7U4M2C1
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

206403:YH65 RS03745
gene id: 206403:YH65_RS03745
uniprot id: A0A7U4M310
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Cell inner membrane
messages: Membrane

206403:YH65 RS10915
gene id: 206403:YH65_RS10915
uniprot id: A0A7U4M2U6
names: Similarity
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.

206403:YH65 RS02560
gene id: 206403:YH65_RS02560
uniprot id: A0A7U4M030
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

206403:YH65 RS09420
gene id: 206403:YH65_RS09420
uniprot id: A0A7U4M2D0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

206403:YH65 RS02820
gene id: 206403:YH65_RS02820
uniprot id: A0A7U4M068
names: Similarity
messages: Belongs to the CvfB family.

206403:YH65 RS07955
gene id: 206403:YH65_RS07955
uniprot id: A0A7U4RR19
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

206403:YH65 RS01870
gene id: 206403:YH65_RS01870
uniprot id: A0A7U4LZV2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

206403:YH65 RS10560
gene id: 206403:YH65_RS10560
uniprot id: A0A7U4RRH1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

206403:YH65 RS06475
gene id: 206403:YH65_RS06475
uniprot id: A0A7U4RQN9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Cytoplasm
messages: Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

206403:YH65 RS09725
gene id: 206403:YH65_RS09725
uniprot id: A0A7U4RRA9
names: Subcellular Location Annotation
messages: Membrane

206403:YH65 RS06795
gene id: 206403:YH65_RS06795
uniprot id: A0A7U4M1G6
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

206403:YH65 RS07470
gene id: 206403:YH65_RS07470
uniprot id: A0A7U4M201
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

206403:YH65 RS06575
gene id: 206403:YH65_RS06575
uniprot id: A0A7U4M1E7
names: Function
names: Similarity
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.

206403:YH65 RS00840
gene id: 206403:YH65_RS00840
uniprot id: A0A7U4RPY1
names: Similarity
messages: Belongs to the DEAD box helicase family.

206403:YH65 RS00015
gene id: 206403:YH65_RS00015
uniprot id: A0A7U4LZB9
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

206403:YH65 RS08375
gene id: 206403:YH65_RS08375
uniprot id: A0A7U4M2A0
names: Function
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

206403:YH65 RS09225
gene id: 206403:YH65_RS09225
uniprot id: A0A7U4RR96
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

206403:YH65 RS07935
gene id: 206403:YH65_RS07935
uniprot id: A0A7U4RR20
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

206403:YH65 RS09835
gene id: 206403:YH65_RS09835
uniprot id: A0A7U4M2H8
names: Function
names: Similarity
messages: Acts on leucine, isoleucine and valine.
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

206403:YH65 RS03195
gene id: 206403:YH65_RS03195
uniprot id: A0A7U4M0A5
names: Similarity
messages: Belongs to the ParB family.

206403:YH65 RS00045
gene id: 206403:YH65_RS00045
uniprot id: A0A7U4LZC5
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family.
messages: Homopolymer.

206403:YH65 RS04590
gene id: 206403:YH65_RS04590
uniprot id: A0A7U4M0Q7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsuA/YedE (TC 9.B.102) family.
messages: Cell inner membrane
messages: Membrane

206403:YH65 RS09080
gene id: 206403:YH65_RS09080
uniprot id: A0A7U4M259
names: Caution
names: Function
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.

206403:YH65 RS03520
gene id: 206403:YH65_RS03520
uniprot id: A0A7U4M0G4
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PdxA family.
messages: Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L-threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP).
messages: Cytoplasm
messages: Homodimer.
messages: The active site is located at the dimer interface.

206403:YH65 RS07135
gene id: 206403:YH65_RS07135
uniprot id: A0A7U4RQY7
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. CpsB/CapC family.

206403:YH65 RS02435
gene id: 206403:YH65_RS02435
uniprot id: A0A7U4M041
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

206403:YH65 RS08220
gene id: 206403:YH65_RS08220
uniprot id: A0A7U4M1X6
names: Subcellular Location Annotation
messages: Membrane

206403:YH65 RS03235
gene id: 206403:YH65_RS03235
uniprot id: A0A7U4RQ63
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Cell inner membrane
messages: Membrane

206403:YH65 RS05080
gene id: 206403:YH65_RS05080
uniprot id: A0A7U4M0X9
names: Subcellular Location Annotation
messages: Cytoplasm

206403:YH65 RS02900
gene id: 206403:YH65_RS02900
uniprot id: A0A7U4M0A3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
messages: Cytoplasm
messages: Homotrimer.
messages: In the C-terminal section; belongs to the transferase hexapeptide repeat family.
messages: In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

206403:YH65 RS03200
gene id: 206403:YH65_RS03200
uniprot id: A0A7U4M0B4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase B chain family.
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: Membrane

206403:YH65 RS05490
gene id: 206403:YH65_RS05490
uniprot id: A0A7U4M121
names: Subcellular Location Annotation
messages: Mitochondrion matrix

206403:YH65 RS03275
gene id: 206403:YH65_RS03275
uniprot id: A0A7U4M311
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

206403:YH65 RS07570
gene id: 206403:YH65_RS07570
uniprot id: A0A7U4M209
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

206403:YH65 RS10655
gene id: 206403:YH65_RS10655
uniprot id: A0A7U4M2R8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

206403:YH65 RS07110
gene id: 206403:YH65_RS07110
uniprot id: A0A7U4M1K2
names: Similarity
messages: Belongs to the thymidylate kinase family.

206403:YH65 RS00585
gene id: 206403:YH65_RS00585
uniprot id: A0A7U4LZF6
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

206403:YH65 RS10000
gene id: 206403:YH65_RS10000
uniprot id: A0A7U4RRD8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. MoaA family.
messages: Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.
messages: Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
messages: Monomer and homodimer.

206403:YH65 RS03835
gene id: 206403:YH65_RS03835
uniprot id: A0A7U4M0I2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the QueC family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).

206403:YH65 RS03560
gene id: 206403:YH65_RS03560
uniprot id: A0A7U4M0G6
names: Similarity
messages: Belongs to the ClpX chaperone family. HslU subfamily.

206403:YH65 RS08365
gene id: 206403:YH65_RS08365
uniprot id: A0A7U4M1Z2
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

206403:YH65 RS03755
gene id: 206403:YH65_RS03755
uniprot id: A0A7U4M0J7
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

206403:YH65 RS04650
gene id: 206403:YH65_RS04650
uniprot id: A0A7U4M0T6
names: Cofactor
names: PTM
names: Subcellular Location Annotation
messages: Binds 2 heme groups per subunit.
messages: Binds 2 heme groups.
messages: Periplasm

206403:YH65 RS08490
gene id: 206403:YH65_RS08490
uniprot id: A0A7U4M249
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

206403:YH65 RS02905
gene id: 206403:YH65_RS02905
uniprot id: A0A7U4M087
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

206403:YH65 RS05995
gene id: 206403:YH65_RS05995
uniprot id: A0A7U4M177
names: Caution
names: Function
names: PTM
names: Similarity
messages: Acetylated. Deacetylation by the SIR2-homolog deacetylase activates the enzyme.
messages: Belongs to the ATP-dependent AMP-binding enzyme family.
messages: Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

206403:YH65 RS04180
gene id: 206403:YH65_RS04180
uniprot id: A0A7U4M0Q2
names: Similarity
messages: Belongs to the histone deacetylase family.

206403:YH65 RS08105
gene id: 206403:YH65_RS08105
uniprot id: A0A7U4M270
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

206403:YH65 RS08100
gene id: 206403:YH65_RS08100
uniprot id: A0A7U4M1W2
names: Subcellular Location Annotation
messages: Mitochondrion

206403:YH65 RS01815
gene id: 206403:YH65_RS01815
uniprot id: A0A7U4RPY5
names: Subcellular Location Annotation
messages: Membrane

206403:YH65 RS03525
gene id: 206403:YH65_RS03525
uniprot id: A0A7U4M0E8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PNP synthase family.
messages: Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.
messages: Cytoplasm
messages: Homooctamer; tetramer of dimers.

206403:YH65 RS00665
gene id: 206403:YH65_RS00665
uniprot id: A0A7U4LZG2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the BPG-independent phosphoglycerate mutase family.
messages: Binds 2 manganese ions per subunit.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: Monomer.

206403:YH65 RS09845
gene id: 206403:YH65_RS09845
uniprot id: A0A7U4M2G2
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the C-terminal section; belongs to the PRA-PH family.
messages: In the N-terminal section; belongs to the PRA-CH family.

206403:YH65 RS02670
gene id: 206403:YH65_RS02670
uniprot id: A0A7U4M082
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

206403:YH65 RS10895
gene id: 206403:YH65_RS10895
uniprot id: A0A7U4RRI2
names: Function
names: Similarity
messages: Belongs to the nucleoside phosphorylase PpnP family.
messages: Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions.

206403:YH65 RS06775
gene id: 206403:YH65_RS06775
uniprot id: A0A7U4M1R8
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta chain.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.

206403:YH65 RS05880
gene id: 206403:YH65_RS05880
uniprot id: A0A7U4RQP8
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

206403:YH65 RS08785
gene id: 206403:YH65_RS08785
uniprot id: A0A7U4M235
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

206403:YH65 RS10905
gene id: 206403:YH65_RS10905
uniprot id: A0A7U4M2T7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.
messages: Binds 2 iron ions per subunit.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

206403:YH65 RS05210
gene id: 206403:YH65_RS05210
uniprot id: A0A7U4RQG2
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

206403:YH65 RS00035
gene id: 206403:YH65_RS00035
uniprot id: A0A7U4RPT3
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

206403:YH65 RS05895
gene id: 206403:YH65_RS05895
uniprot id: A0A7U4M155
names: Similarity
messages: Belongs to the UPF0166 family.

206403:YH65 RS01620
gene id: 206403:YH65_RS01620
uniprot id: A0A7U4LZW1
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

206403:YH65 RS00695
gene id: 206403:YH65_RS00695
uniprot id: A0A7U4RPS4
names: Subcellular Location Annotation
messages: Membrane

206403:YH65 RS10185
gene id: 206403:YH65_RS10185
uniprot id: A0A7U4M2J9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

206403:YH65 RS07975
gene id: 206403:YH65_RS07975
uniprot id: A0A7U4M1V0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily.
messages: Catalyzes the transfer of the alpha-amino group from S-adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only aminotransferase known to utilize SAM as an amino donor.
messages: Cytoplasm
messages: Homodimer.

206403:YH65 RS05360
gene id: 206403:YH65_RS05360
uniprot id: A0A7U4M0Z5
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

206403:YH65 RS08545
gene id: 206403:YH65_RS08545
uniprot id: A0A7U4RR33
names: Caution
names: Function
names: Similarity
messages: Belongs to the IspF family.
messages: Bifunctional enzyme that catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF).
messages: In the C-terminal section; belongs to the IspF family.
messages: In the N-terminal section; belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

206403:YH65 RS06215
gene id: 206403:YH65_RS06215
uniprot id: A0A7U4RQR8
names: Similarity
messages: In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family.

206403:YH65 RS04020
gene id: 206403:YH65_RS04020
uniprot id: A0A7U4RQB1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

206403:YH65 RS07325
gene id: 206403:YH65_RS07325
uniprot id: A0A7U4RQY6
names: Function
names: Similarity
messages: Belongs to the CobU/CobP family.
messages: Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate.

206403:YH65 RS01845
gene id: 206403:YH65_RS01845
uniprot id: A0A7U4RQ38
names: Similarity
messages: Belongs to the ClpA/ClpB family.

206403:YH65 RS10575
gene id: 206403:YH65_RS10575
uniprot id: A0A7U4M2P7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

206403:YH65 RS05750
gene id: 206403:YH65_RS05750
uniprot id: A0A7U4M143
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

206403:YH65 RS03750
gene id: 206403:YH65_RS03750
uniprot id: A0A7U4M0H8
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

206403:YH65 RS07420
gene id: 206403:YH65_RS07420
uniprot id: A0A7U4M1N7
names: Similarity
messages: Belongs to the glutamate synthase family.

206403:YH65 RS10995
gene id: 206403:YH65_RS10995
uniprot id: A0A7U4RRJ6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

206403:YH65 RS02060
gene id: 206403:YH65_RS02060
uniprot id: A0A7U4RQ26
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Mg(2+). Can also accept Mn(2+).

206403:YH65 RS05940
gene id: 206403:YH65_RS05940
uniprot id: A0A7U4RQQ5
names: Function
names: Similarity
messages: Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.

206403:YH65 RS01175
gene id: 206403:YH65_RS01175
uniprot id: A0A7U4LZN9
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

206403:YH65 RS03715
gene id: 206403:YH65_RS03715
uniprot id: A0A7U4M0G2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

206403:YH65 RS04095
gene id: 206403:YH65_RS04095
uniprot id: A0A7U4RQE1
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

206403:YH65 RS09430
gene id: 206403:YH65_RS09430
uniprot id: A0A7U4RR52
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

206403:YH65 RS03630
gene id: 206403:YH65_RS03630
uniprot id: A0A7U4RQ74
names: Similarity
messages: Belongs to the P(II) protein family.

206403:YH65 RS03995
gene id: 206403:YH65_RS03995
uniprot id: A0A7U4M0I5
names: Function
names: Similarity
messages: Belongs to the GTP-binding SRP family.
messages: Necessary for flagellar biosynthesis. May be involved in translocation of the flagellum.

206403:YH65 RS03375
gene id: 206403:YH65_RS03375
uniprot id: A0A7U4RQA2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 2 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

206403:YH65 RS01340
gene id: 206403:YH65_RS01340
uniprot id: A0A7U4RPY6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Belongs to the NnrE/AIBP family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

206403:YH65 RS05865
gene id: 206403:YH65_RS05865
uniprot id: A0A7U4M149
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

206403:YH65 RS06630
gene id: 206403:YH65_RS06630
uniprot id: A0A7U4M1I2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

206403:YH65 RS05860
gene id: 206403:YH65_RS05860
uniprot id: A0A7U4RQQ0
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

206403:YH65 RS00005
gene id: 206403:YH65_RS00005
uniprot id: A0A7U4RPP7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

206403:YH65 RS00660
gene id: 206403:YH65_RS00660
uniprot id: A0A7U4LZH9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane
messages: Membrane

206403:YH65 RS05105
gene id: 206403:YH65_RS05105
uniprot id: A0A7U4M0W7
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
messages: In the C-terminal section; belongs to the NAD synthetase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

206403:YH65 RS01125
gene id: 206403:YH65_RS01125
uniprot id: A0A7U4LZL9
names: Similarity
messages: Belongs to the SUI1 family.

206403:YH65 RS03535
gene id: 206403:YH65_RS03535
uniprot id: A0A7U4M0J6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.

206403:YH65 RS07330
gene id: 206403:YH65_RS07330
uniprot id: A0A7U4M1R4
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

206403:YH65 RS07125
gene id: 206403:YH65_RS07125
uniprot id: A0A7U4M1V9
names: Similarity
messages: Belongs to the mannose-6-phosphate isomerase type 2 family.

206403:YH65 RS09855
gene id: 206403:YH65_RS09855
uniprot id: A0A7U4M2G3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

206403:YH65 RS02155
gene id: 206403:YH65_RS02155
uniprot id: A0A7U4LZZ9
names: Function
names: Similarity
messages: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.
messages: In the C-terminal section; belongs to the HTP reductase family.
messages: In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family.

206403:YH65 RS09910
gene id: 206403:YH65_RS09910
uniprot id: A0A7U4RRD3
names: Similarity
messages: Belongs to the UPF0234 family.

206403:YH65 RS03120
gene id: 206403:YH65_RS03120
uniprot id: A0A7U4M097
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

206403:YH65 RS01450
gene id: 206403:YH65_RS01450
uniprot id: A0A7U4RPV8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PAPS reductase family. CysD subfamily.
messages: Heterodimer composed of CysD, the smaller subunit, and CysN.
messages: With CysN forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway. APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD.

206403:YH65 RS04585
gene id: 206403:YH65_RS04585
uniprot id: A0A7U4RQH3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsuA/YedE (TC 9.B.102) family.
messages: Cell inner membrane
messages: Membrane

206403:YH65 RS01395
gene id: 206403:YH65_RS01395
uniprot id: A0A7U4LZP4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family.
messages: Binds 1 Mg(2+) ion per subunit. Can also utilize other divalent metal cations, such as Ca(2+), Mn(2+) and Co(2+).
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
messages: Homodimer.

206403:YH65 RS08215
gene id: 206403:YH65_RS08215
uniprot id: A0A7U4M1X5
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

206403:YH65 RS00455
gene id: 206403:YH65_RS00455
uniprot id: A0A7U4RPR5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 49 kDa subunit family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

206403:YH65 RS09965
gene id: 206403:YH65_RS09965
uniprot id: A0A7U4RRD7
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.

206403:YH65 RS09445
gene id: 206403:YH65_RS09445
uniprot id: A0A7U4M2B9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

206403:YH65 RS05720
gene id: 206403:YH65_RS05720
uniprot id: A0A7U4M175
names: Cofactor
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.

206403:YH65 RS03685
gene id: 206403:YH65_RS03685
uniprot id: A0A7U4RQD0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm

206403:YH65 RS08950
gene id: 206403:YH65_RS08950
uniprot id: A0A7U4M252
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

206403:YH65 RS00020
gene id: 206403:YH65_RS00020
uniprot id: A0A7U4LZA1
names: Similarity
messages: Belongs to the RecJ family.

206403:YH65 RS03435
gene id: 206403:YH65_RS03435
uniprot id: A0A7U4M0D5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 2 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

206403:YH65 RS06325
gene id: 206403:YH65_RS06325
uniprot id: A0A7U4M341
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

206403:YH65 RS03705
gene id: 206403:YH65_RS03705
uniprot id: A0A7U4M0K2
names: Similarity
messages: Belongs to the threonine synthase family.

206403:YH65 RS09950
gene id: 206403:YH65_RS09950
uniprot id: A0A7U4M2I2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

206403:YH65 RS01565
gene id: 206403:YH65_RS01565
uniprot id: A0A7U4LZR5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

206403:YH65 RS00065
gene id: 206403:YH65_RS00065
uniprot id: A0A7U4LZC6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

206403:YH65 RS03365
gene id: 206403:YH65_RS03365
uniprot id: A0A7U4M0C9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

206403:YH65 RS09670
gene id: 206403:YH65_RS09670
uniprot id: A0A7U4M2D7
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

206403:YH65 RS08460
gene id: 206403:YH65_RS08460
uniprot id: A0A7U4M210
names: Activity Regulation
names: Caution
names: Domain
names: Function
names: Similarity
messages: Belongs to the GlnD family.
messages: Has four distinct domains: an N-terminal nucleotidyltransferase (NT) domain responsible for UTase activity, a central HD domain that encodes UR activity, and two C-terminal ACT domains that seem to have a role in glutamine sensing.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen metabolism.
messages: Uridylyltransferase (UTase) activity is inhibited by glutamine, while glutamine activates uridylyl-removing (UR) activity.

206403:YH65 RS09320
gene id: 206403:YH65_RS09320
uniprot id: A0A7U4M295
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein uS19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein uS19.

206403:YH65 RS09945
gene id: 206403:YH65_RS09945
uniprot id: A0A7U4M2I1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

206403:YH65 RS01055
gene id: 206403:YH65_RS01055
uniprot id: A0A7U4RPX1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STT3 family.
messages: Membrane

206403:YH65 RS09960
gene id: 206403:YH65_RS09960
uniprot id: A0A7U4M2K4
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

206403:YH65 RS04680
gene id: 206403:YH65_RS04680
uniprot id: A0A7U4M0V1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

206403:YH65 RS00515
gene id: 206403:YH65_RS00515
uniprot id: A0A7U4RPU3
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

206403:YH65 RS09515
gene id: 206403:YH65_RS09515
uniprot id: A0A7U4M2B4
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

206403:YH65 RS01885
gene id: 206403:YH65_RS01885
uniprot id: A0A7U4RPX9
names: Function
names: Subcellular Location Annotation
messages: Catalyzes the Claisen rearrangement of chorismate to prephenate and the decarboxylation/dehydration of prephenate to phenylpyruvate.
messages: Cytoplasm

206403:YH65 RS00485
gene id: 206403:YH65_RS00485
uniprot id: A0A7U4LZH5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 23 kDa subunit family.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

206403:YH65 RS01890
gene id: 206403:YH65_RS01890
uniprot id: A0A7U4LZW9
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

206403:YH65 RS01665
gene id: 206403:YH65_RS01665
uniprot id: A0A7U4RQ29
names: Similarity
messages: Belongs to the ModE family.

206403:YH65 RS05815
gene id: 206403:YH65_RS05815
uniprot id: A0A7U4M148
names: Similarity
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.

206403:YH65 RS08260
gene id: 206403:YH65_RS08260
uniprot id: A0A7U4RR18
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

206403:YH65 RS03465
gene id: 206403:YH65_RS03465
uniprot id: A0A7U4M304
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the R-transferase family. Bpt subfamily.
messages: Cytoplasm
messages: Functions in the N-end rule pathway of protein degradation where it conjugates Leu from its aminoacyl-tRNA to the N-termini of proteins containing an N-terminal aspartate or glutamate.

206403:YH65 RS02400
gene id: 206403:YH65_RS02400
uniprot id: A0A7U4M053
names: Similarity
messages: Belongs to the phosphohexose mutase family.

206403:YH65 RS01880
gene id: 206403:YH65_RS01880
uniprot id: A0A7U4LZZ8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

206403:YH65 RS06920
gene id: 206403:YH65_RS06920
uniprot id: A0A7U4M1H8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

206403:YH65 RS10965
gene id: 206403:YH65_RS10965
uniprot id: A0A7U4M2U1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

206403:YH65 RS02180
gene id: 206403:YH65_RS02180
uniprot id: A0A7U4M022
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

206403:YH65 RS00535
gene id: 206403:YH65_RS00535
uniprot id: A0A7U4RPR8
names: Function
names: Similarity
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
messages: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.

206403:YH65 RS05835
gene id: 206403:YH65_RS05835
uniprot id: A0A7U4M159
names: Similarity
messages: Belongs to the desulfoferrodoxin family.

206403:YH65 RS09075
gene id: 206403:YH65_RS09075
uniprot id: A0A7U4RR70
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with bS18 to 16S ribosomal RNA.

206403:YH65 RS08110
gene id: 206403:YH65_RS08110
uniprot id: A0A7U4M1Z8
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

206403:YH65 RS08895
gene id: 206403:YH65_RS08895
uniprot id: A0A7U4M368
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. Cx-SAM synthase family.
messages: Catalyzes the conversion of S-adenosyl-L-methionine (SAM) to carboxy-S-adenosyl-L-methionine (Cx-SAM).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

206403:YH65 RS08985
gene id: 206403:YH65_RS08985
uniprot id: A0A7U4M299
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

206403:YH65 RS01200
gene id: 206403:YH65_RS01200
uniprot id: A0A7U4M2X6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

206403:YH65 RS09145
gene id: 206403:YH65_RS09145
uniprot id: A0A7U4M2B5
names: Similarity
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.

206403:YH65 RS03610
gene id: 206403:YH65_RS03610
uniprot id: A0A7U4RQB4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
messages: Belongs to the KdsB family.
messages: Cytoplasm

206403:YH65 RS07025
gene id: 206403:YH65_RS07025
uniprot id: A0A7U4M1J2
names: Similarity
messages: Belongs to the phD/YefM antitoxin family.

206403:YH65 RS02455
gene id: 206403:YH65_RS02455
uniprot id: A0A7U4RQ75
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

206403:YH65 RS01265
gene id: 206403:YH65_RS01265
uniprot id: A0A7U4RPV0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

206403:YH65 RS11115
gene id: 206403:YH65_RS11115
uniprot id: A0A7U4RRK8
names: Similarity
messages: Belongs to the truncated hemoglobin family. Group II subfamily.

206403:YH65 RS04360
gene id: 206403:YH65_RS04360
uniprot id: A0A7U4RQB0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class II aldolase/RraA-like family.
messages: Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2-oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions.
messages: Homotrimer.

206403:YH65 RS09680
gene id: 206403:YH65_RS09680
uniprot id: A0A7U4M2E3
names: Cofactor
names: PTM
names: Subcellular Location Annotation
messages: Binds 2 heme groups per subunit.
messages: Binds 2 heme groups.
messages: Periplasm

206403:YH65 RS04760
gene id: 206403:YH65_RS04760
uniprot id: A0A7U4RQI4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

206403:YH65 RS09150
gene id: 206403:YH65_RS09150
uniprot id: A0A7U4RR88
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: The fumarate reductase enzyme complex is required for fumarate respiration. This subunit anchors the complex in the membrane and binds a diheme cytochrome b.

206403:YH65 RS09920
gene id: 206403:YH65_RS09920
uniprot id: A0A7U4RR91
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

206403:YH65 RS08605
gene id: 206403:YH65_RS08605
uniprot id: A0A7U4M227
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NrfD family.
messages: Membrane

206403:YH65 RS10270
gene id: 206403:YH65_RS10270
uniprot id: A0A7U4M2M1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

206403:YH65 RS10165
gene id: 206403:YH65_RS10165
uniprot id: A0A7U4M2M5
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Binds 1 copper ion per subunit, denoted as copper B.
messages: Binds 2 heme groups per subunit, denoted as high- and low-spin.
messages: Membrane

206403:YH65 RS10260
gene id: 206403:YH65_RS10260
uniprot id: A0A7U4RRD9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

206403:YH65 RS10595
gene id: 206403:YH65_RS10595
uniprot id: A0A7U4RRD0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

206403:YH65 RS09020
gene id: 206403:YH65_RS09020
uniprot id: A0A7U4M282
names: Subcellular Location Annotation
messages: Membrane

206403:YH65 RS07295
gene id: 206403:YH65_RS07295
uniprot id: A0A7U4RQY1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

206403:YH65 RS07220
gene id: 206403:YH65_RS07220
uniprot id: A0A7U4M1L7
names: Subcellular Location Annotation
messages: Membrane

206403:YH65 RS06260
gene id: 206403:YH65_RS06260
uniprot id: A0A7U4M1J4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC41A transporter family.
messages: Membrane

206403:YH65 RS01215
gene id: 206403:YH65_RS01215
uniprot id: A0A7U4LZP8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

206403:YH65 RS01930
gene id: 206403:YH65_RS01930
uniprot id: A0A7U4RQ28
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsX family.
messages: Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
messages: Cytoplasm
messages: Homodimer. Probably interacts with PlsY.

206403:YH65 RS01915
gene id: 206403:YH65_RS01915
uniprot id: A0A7U4LZZ4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

206403:YH65 RS08710
gene id: 206403:YH65_RS08710
uniprot id: A0A7U4M274
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

206403:YH65 RS03445
gene id: 206403:YH65_RS03445
uniprot id: A0A7U4M0D6
names: Function
names: Similarity
messages: Belongs to the PurU family.
messages: Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).

206403:YH65 RS07555
gene id: 206403:YH65_RS07555
uniprot id: A0A7U4M1Q0
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvA family.
messages: Cytoplasm
messages: Has three domains with a flexible linker between the domains II and III and assumes an 'L' shape. Domain III is highly mobile and contacts RuvB.
messages: Homotetramer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

206403:YH65 RS06155
gene id: 206403:YH65_RS06155
uniprot id: A0A7U4M1A4
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.

206403:YH65 RS00325
gene id: 206403:YH65_RS00325
uniprot id: A0A7U4RPS9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase H family.
messages: Binds 1 Mg(2+) ion per subunit. May bind a second metal ion at a regulatory site, or after substrate binding.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Monomer.

206403:YH65 RS07485
gene id: 206403:YH65_RS07485
uniprot id: A0A7U4RR05
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Membrane

206403:YH65 RS03170
gene id: 206403:YH65_RS03170
uniprot id: A0A7U4M0A2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

206403:YH65 RS04945
gene id: 206403:YH65_RS04945
uniprot id: A0A7U4M0U7
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

206403:YH65 RS04485
gene id: 206403:YH65_RS04485
uniprot id: A0A7U4M0S3
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

206403:YH65 RS07270
gene id: 206403:YH65_RS07270
uniprot id: A0A7U4M1P9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm

206403:YH65 RS10960
gene id: 206403:YH65_RS10960
uniprot id: A0A7U4M396
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

206403:YH65 RS00700
gene id: 206403:YH65_RS00700
uniprot id: A0A7U4LZI4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MgtC/SapB family.
messages: Membrane

206403:YH65 RS06510
gene id: 206403:YH65_RS06510
uniprot id: A0A7U4M1G8
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

206403:YH65 RS01090
gene id: 206403:YH65_RS01090
uniprot id: A0A7U4LZP2
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

206403:YH65 RS00605
gene id: 206403:YH65_RS00605
uniprot id: A0A7U4RPS0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

206403:YH65 RS04770
gene id: 206403:YH65_RS04770
uniprot id: A0A7U4M335
names: Similarity
messages: Belongs to the bacterial solute-binding protein 9 family.

206403:YH65 RS06275
gene id: 206403:YH65_RS06275
uniprot id: A0A7U4RQS4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0718 family.
messages: Cell membrane
messages: Membrane

206403:YH65 RS10640
gene id: 206403:YH65_RS10640
uniprot id: A0A7U4RRG7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

206403:YH65 RS04700
gene id: 206403:YH65_RS04700
uniprot id: A0A7U4M0W4
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

206403:YH65 RS01290
gene id: 206403:YH65_RS01290
uniprot id: A0A7U4LZS9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 2 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

206403:YH65 RS08270
gene id: 206403:YH65_RS08270
uniprot id: A0A7U4M208
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.
messages: There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors.

206403:YH65 RS02445
gene id: 206403:YH65_RS02445
uniprot id: A0A7U4M045
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

206403:YH65 RS01670
gene id: 206403:YH65_RS01670
uniprot id: A0A7U4RQ11
names: Similarity
messages: Belongs to the bacterial solute-binding protein ModA family.

206403:YH65 RS02535
gene id: 206403:YH65_RS02535
uniprot id: A0A7U4RQ81
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

206403:YH65 RS00975
gene id: 206403:YH65_RS00975
uniprot id: A0A7U4LZM1
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dCTP deaminase family.
messages: Catalyzes the deamination of dCTP to dUTP.
messages: Homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

206403:YH65 RS10465
gene id: 206403:YH65_RS10465
uniprot id: A0A7U4M2P8
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

206403:YH65 RS07095
gene id: 206403:YH65_RS07095
uniprot id: A0A7U4RQS2
names: Subcellular Location Annotation
messages: Membrane

206403:YH65 RS09335
gene id: 206403:YH65_RS09335
uniprot id: A0A7U4RR97
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

206403:YH65 RS09345
gene id: 206403:YH65_RS09345
uniprot id: A0A7U4RR47
names: Similarity
messages: Belongs to the UPF0235 family.

206403:YH65 RS06315
gene id: 206403:YH65_RS06315
uniprot id: A0A7U4M1A6
names: Subcellular Location Annotation
messages: Membrane

206403:YH65 RS00595
gene id: 206403:YH65_RS00595
uniprot id: A0A7U4RPU8
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

206403:YH65 RS09565
gene id: 206403:YH65_RS09565
uniprot id: A0A7U4M2C3
names: Caution
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. NasA/NapA/NarB subfamily.
messages: Binds 1 [4Fe-4S] cluster.
messages: Binds 1 molybdenum-bis(molybdopterin guanine dinucleotide) (Mo-bis-MGD) cofactor per subunit.
messages: Catalytic subunit of the nitrate reductase complex NapAB. Receives electrons from NapB and catalyzes the reduction of nitrate to nitrite.
messages: Component of the nitrate reductase NapAB complex composed of NapA and NapB.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Predicted to be exported by the Tat system. The position of the signal peptide cleavage has not been experimentally proven.
messages: Secreted

206403:YH65 RS07610
gene id: 206403:YH65_RS07610
uniprot id: A0A7U4RR00
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

206403:YH65 RS08455
gene id: 206403:YH65_RS08455
uniprot id: A0A7U4RR28
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the radical SAM superfamily. MqnE family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3-[(1-carboxyvinyl)oxy]benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate.

206403:YH65 RS00770
gene id: 206403:YH65_RS00770
uniprot id: A0A7U4LZH2
names: Subcellular Location Annotation
messages: Membrane

206403:YH65 RS03740
gene id: 206403:YH65_RS03740
uniprot id: A0A7U4RQ95
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

206403:YH65 RS00270
gene id: 206403:YH65_RS00270
uniprot id: A0A7U4RPQ8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

206403:YH65 RS09625
gene id: 206403:YH65_RS09625
uniprot id: A0A7U4M2H7
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

206403:YH65 RS09035
gene id: 206403:YH65_RS09035
uniprot id: A0A7U4RR63
names: Similarity
messages: Belongs to the catalase family.

206403:YH65 RS10025
gene id: 206403:YH65_RS10025
uniprot id: A0A7U4M2I4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

206403:YH65 RS08940
gene id: 206403:YH65_RS08940
uniprot id: A0A7U4M271
names: Similarity
messages: Belongs to the aspartokinase family.

206403:YH65 RS07630
gene id: 206403:YH65_RS07630
uniprot id: A0A7U4M1R3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Probable transporter of a GTP-driven Fe(2+) uptake system.

206403:YH65 RS06950
gene id: 206403:YH65_RS06950
uniprot id: A0A7U4M1U3
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

206403:YH65 RS03635
gene id: 206403:YH65_RS03635
uniprot id: A0A7U4M0G8
names: Subcellular Location Annotation
messages: Membrane

206403:YH65 RS07720
gene id: 206403:YH65_RS07720
uniprot id: A0A7U4RQV6
names: Similarity
messages: Belongs to the methyltransferase superfamily. Arsenite methyltransferase family.

206403:YH65 RS03870
gene id: 206403:YH65_RS03870
uniprot id: A0A7U4M0K0
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

206403:YH65 RS00235
gene id: 206403:YH65_RS00235
uniprot id: A0A7U4LZD9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Cytoplasm

206403:YH65 RS05015
gene id: 206403:YH65_RS05015
uniprot id: A0A7U4RQL9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

206403:YH65 RS00085
gene id: 206403:YH65_RS00085
uniprot id: A0A7U4RPQ1
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MobA family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The N-terminal domain determines nucleotide recognition and specific binding, while the C-terminal domain determines the specific binding to the target protein.
messages: Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor.

206403:YH65 RS03640
gene id: 206403:YH65_RS03640
uniprot id: A0A7U4RQ92
names: Similarity
messages: Belongs to the P(II) protein family.

206403:YH65 RS02935
gene id: 206403:YH65_RS02935
uniprot id: A0A7U4RQ77
names: Similarity
messages: Belongs to the serine/threonine dehydratase family.

206403:YH65 RS00865
gene id: 206403:YH65_RS00865
uniprot id: A0A7U4RPW1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

206403:YH65 RS01935
gene id: 206403:YH65_RS01935
uniprot id: A0A7U4LZW6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

206403:YH65 RS10050
gene id: 206403:YH65_RS10050
uniprot id: A0A7U4RRE1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LuxS family.
messages: Binds 1 Fe cation per subunit.
messages: Homodimer.
messages: Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD).

206403:YH65 RS00990
gene id: 206403:YH65_RS00990
uniprot id: A0A7U4LZP3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

206403:YH65 RS07795
gene id: 206403:YH65_RS07795
uniprot id: A0A7U4RQW1
names: Subcellular Location Annotation
messages: Membrane

206403:YH65 RS04330
gene id: 206403:YH65_RS04330
uniprot id: A0A7U4M0M7
names: Similarity
messages: Belongs to the ArsC family.

206403:YH65 RS10715
gene id: 206403:YH65_RS10715
uniprot id: A0A7U4RRH3
names: Subcellular Location Annotation
messages: Membrane

206403:YH65 RS04210
gene id: 206403:YH65_RS04210
uniprot id: A0A7U4M0N6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homodimer.

206403:YH65 RS05975
gene id: 206403:YH65_RS05975
uniprot id: A0A7U4M163
names: Similarity
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 4 (UDGa) family.

206403:YH65 RS10525
gene id: 206403:YH65_RS10525
uniprot id: A0A7U4M2P6
names: Similarity
messages: Belongs to the UPF0758 family.

206403:YH65 RS01740
gene id: 206403:YH65_RS01740
uniprot id: A0A7U4LZU2
names: Cofactor
names: Function
messages: Binds 2 [4Fe-4S] clusters.
messages: Component of a complex that catalyzes the oxidation of glycolate to glyoxylate.

206403:YH65 RS01965
gene id: 206403:YH65_RS01965
uniprot id: A0A7U4M008
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm

206403:YH65 RS05330
gene id: 206403:YH65_RS05330
uniprot id: A0A7U4M106
names: Subcellular Location Annotation
messages: Membrane

206403:YH65 RS00720
gene id: 206403:YH65_RS00720
uniprot id: A0A7U4LZL3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

206403:YH65 RS02210
gene id: 206403:YH65_RS02210
uniprot id: A0A7U4LZY4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

206403:YH65 RS01220
gene id: 206403:YH65_RS01220
uniprot id: A0A7U4M2Y0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

206403:YH65 RS02960
gene id: 206403:YH65_RS02960
uniprot id: A0A7U4M093
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

206403:YH65 RS09760
gene id: 206403:YH65_RS09760
uniprot id: A0A7U4RR82
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

206403:YH65 RS03645
gene id: 206403:YH65_RS03645
uniprot id: A0A7U4M0G9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

206403:YH65 RS06570
gene id: 206403:YH65_RS06570
uniprot id: A0A7U4M1I1
names: Subcellular Location Annotation
messages: Membrane

206403:YH65 RS09000
gene id: 206403:YH65_RS09000
uniprot id: A0A7U4M247
names: Similarity
messages: Belongs to the DprA/Smf family.

206403:YH65 RS03340
gene id: 206403:YH65_RS03340
uniprot id: A0A7U4M0E1
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

206403:YH65 RS03550
gene id: 206403:YH65_RS03550
uniprot id: A0A7U4RQ83
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

206403:YH65 RS05370
gene id: 206403:YH65_RS05370
uniprot id: A0A7U4M3D0
names: Similarity
messages: Belongs to the SAICAR synthetase family.

206403:YH65 RS08400
gene id: 206403:YH65_RS08400
uniprot id: A0A7U4M1Z5
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

206403:YH65 RS02715
gene id: 206403:YH65_RS02715
uniprot id: A0A7U4M063
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

206403:YH65 RS06810
gene id: 206403:YH65_RS06810
uniprot id: A0A7U4RQW0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

206403:YH65 RS05235
gene id: 206403:YH65_RS05235
uniprot id: A0A7U4M119
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

206403:YH65 RS01980
gene id: 206403:YH65_RS01980
uniprot id: A0A7U4RRK4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

206403:YH65 RS10835
gene id: 206403:YH65_RS10835
uniprot id: A0A7U4M2T0
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.

206403:YH65 RS08810
gene id: 206403:YH65_RS08810
uniprot id: A0A7U4RR58
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

206403:YH65 RS04495
gene id: 206403:YH65_RS04495
uniprot id: A0A7U4RQH0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioester dehydratase family. FabZ subfamily.
messages: Cytoplasm
messages: Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.

206403:YH65 RS07760
gene id: 206403:YH65_RS07760
uniprot id: A0A7U4RR22
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0718 family.
messages: Cell membrane
messages: Membrane

206403:YH65 RS05855
gene id: 206403:YH65_RS05855
uniprot id: A0A7U4RQR6
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

206403:YH65 RS00055
gene id: 206403:YH65_RS00055
uniprot id: A0A7U4LZA9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

206403:YH65 RS02175
gene id: 206403:YH65_RS02175
uniprot id: A0A7U4LZZ6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

206403:YH65 RS06320
gene id: 206403:YH65_RS06320
uniprot id: A0A7U4RQQ1
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

206403:YH65 RS02895
gene id: 206403:YH65_RS02895
uniprot id: A0A7U4M078
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

206403:YH65 RS10985
gene id: 206403:YH65_RS10985
uniprot id: A0A7U4M2X3
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.

206403:YH65 RS00410
gene id: 206403:YH65_RS00410
uniprot id: A0A7U4LZG0
names: Subcellular Location Annotation
messages: Membrane

206403:YH65 RS09015
gene id: 206403:YH65_RS09015
uniprot id: A0A7U4RR76
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

206403:YH65 RS04355
gene id: 206403:YH65_RS04355
uniprot id: A0A7U4M0S8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transglycosylase MltG family.
messages: Cell membrane
messages: Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.

206403:YH65 RS05435
gene id: 206403:YH65_RS05435
uniprot id: A0A7U4RQM2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.

206403:YH65 RS00125
gene id: 206403:YH65_RS00125
uniprot id: A0A7U4RPS6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP G family.
messages: Cell inner membrane
messages: Membrane

206403:YH65 RS03455
gene id: 206403:YH65_RS03455
uniprot id: A0A7U4M0H6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

206403:YH65 RS09160
gene id: 206403:YH65_RS09160
uniprot id: A0A7U4M273
names: Subcellular Location Annotation
messages: Cytoplasm

206403:YH65 RS00075
gene id: 206403:YH65_RS00075
uniprot id: A0A7U4RPQ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0324 family.
messages: Membrane

206403:YH65 RS08955
gene id: 206403:YH65_RS08955
uniprot id: A0A7U4RR59
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TatB family.
messages: Cell membrane

206403:YH65 RS09630
gene id: 206403:YH65_RS09630
uniprot id: A0A7U4RRB7
names: Subcellular Location Annotation
messages: Membrane

206403:YH65 RS10660
gene id: 206403:YH65_RS10660
uniprot id: A0A7U4RRI0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

206403:YH65 RS08875
gene id: 206403:YH65_RS08875
uniprot id: A0A7U4M243
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the shikimate dehydrogenase family.
messages: Homodimer.
messages: Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

206403:YH65 RS10630
gene id: 206403:YH65_RS10630
uniprot id: A0A7U4M2T5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

206403:YH65 RS00445
gene id: 206403:YH65_RS00445
uniprot id: A0A7U4RPR3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 20 kDa subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

206403:YH65 RS04545
gene id: 206403:YH65_RS04545
uniprot id: A0A7U4RQE2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

206403:YH65 RS09665
gene id: 206403:YH65_RS09665
uniprot id: A0A7U4RR78
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

206403:YH65 RS02390
gene id: 206403:YH65_RS02390
uniprot id: A0A7U4M005
names: Similarity
messages: Belongs to the UDPGP type 2 family.

206403:YH65 RS02215
gene id: 206403:YH65_RS02215
uniprot id: A0A7U4LZY7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. PrmA family.
messages: Cytoplasm
messages: Methylates ribosomal protein L11.

206403:YH65 RS03860
gene id: 206403:YH65_RS03860
uniprot id: A0A7U4M0J8
names: Similarity
messages: Belongs to the acylphosphatase family.

206403:YH65 RS10585
gene id: 206403:YH65_RS10585
uniprot id: A0A7U4RRH5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

206403:YH65 RS08505
gene id: 206403:YH65_RS08505
uniprot id: A0A7U4M202
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ThiG family.
messages: Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
messages: Cytoplasm
messages: Homotetramer. Forms heterodimers with either ThiH or ThiS.

206403:YH65 RS05595
gene id: 206403:YH65_RS05595
uniprot id: A0A7U4RQN2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Membrane

206403:YH65 RS00505
gene id: 206403:YH65_RS00505
uniprot id: A0A7U4LZF1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Membrane

206403:YH65 RS06945
gene id: 206403:YH65_RS06945
uniprot id: A0A7U4M1I6
names: Function
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. SpeA subfamily.
messages: Catalyzes the biosynthesis of agmatine from arginine.

206403:YH65 RS09255
gene id: 206403:YH65_RS09255
uniprot id: A0A7U4M2B1
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

206403:YH65 RS05060
gene id: 206403:YH65_RS05060
uniprot id: A0A7U4M0W3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Membrane

206403:YH65 RS02420
gene id: 206403:YH65_RS02420
uniprot id: A0A7U4RQ18
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

206403:YH65 RS10625
gene id: 206403:YH65_RS10625
uniprot id: A0A7U4M342
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

206403:YH65 RS08520
gene id: 206403:YH65_RS08520
uniprot id: A0A7U4RR51
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ThiC family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

206403:YH65 RS05245
gene id: 206403:YH65_RS05245
uniprot id: A0A7U4M0Z6
names: Similarity
messages: Belongs to the SufE family.

206403:YH65 RS04925
gene id: 206403:YH65_RS04925
uniprot id: A0A7U4M0X1
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

206403:YH65 RS08075
gene id: 206403:YH65_RS08075
uniprot id: A0A7U4RQY0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

206403:YH65 RS10850
gene id: 206403:YH65_RS10850
uniprot id: A0A7U4RRE5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily.
messages: Cytoplasm
messages: Homodimer, may be a subunit of the RNA degradosome.

206403:YH65 RS10880
gene id: 206403:YH65_RS10880
uniprot id: A0A7U4M371
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.

206403:YH65 RS10670
gene id: 206403:YH65_RS10670
uniprot id: A0A7U4RRD6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

206403:YH65 RS01455
gene id: 206403:YH65_RS01455
uniprot id: A0A7U4LZR9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.
messages: Heterodimer composed of CysD, the smaller subunit, and CysN.
messages: With CysD forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway. APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD.

206403:YH65 RS09460
gene id: 206403:YH65_RS09460
uniprot id: A0A7U4M2B7
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

206403:YH65 RS08390
gene id: 206403:YH65_RS08390
uniprot id: A0A7U4RR39
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

206403:YH65 RS02890
gene id: 206403:YH65_RS02890
uniprot id: A0A7U4M086
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.

206403:YH65 RS06490
gene id: 206403:YH65_RS06490
uniprot id: A0A7U4M1D6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OadG family.
messages: Catalyzes the decarboxylation of oxaloacetate coupled to Na(+) translocation.
messages: Cell membrane
messages: Heterotrimer of an alpha, a beta and a gamma subunit.
messages: Membrane

206403:YH65 RS09415
gene id: 206403:YH65_RS09415
uniprot id: A0A7U4RRA3
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.

206403:YH65 RS05110
gene id: 206403:YH65_RS05110
uniprot id: A0A7U4M0Z4
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

206403:YH65 RS03300
gene id: 206403:YH65_RS03300
uniprot id: A0A7U4M0F8
names: Similarity
messages: Belongs to the fabD family.

206403:YH65 RS04005
gene id: 206403:YH65_RS04005
uniprot id: A0A7U4M0N7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

206403:YH65 RS06745
gene id: 206403:YH65_RS06745
uniprot id: A0A7U4M1F9
names: Similarity
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.

206403:YH65 RS05395
gene id: 206403:YH65_RS05395
uniprot id: A0A7U4M0Z8
names: Function
names: Similarity
messages: Belongs to the EIF-2B alpha/beta/delta subunits family. MtnA subfamily.
messages: Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).

206403:YH65 RS06540
gene id: 206403:YH65_RS06540
uniprot id: A0A7U4RQU5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SurE nucleotidase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Cytoplasm
messages: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.

206403:YH65 RS05400
gene id: 206403:YH65_RS05400
uniprot id: A0A7U4RQJ2
names: Similarity
names: Subunit
messages: Belongs to the methylthioribose kinase family.
messages: Homodimer.

206403:YH65 RS00895
gene id: 206403:YH65_RS00895
uniprot id: A0A7U4LZM3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

206403:YH65 RS02065
gene id: 206403:YH65_RS02065
uniprot id: A0A7U4M015
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.
messages: In the N-terminal section; belongs to the CobB/CobQ family.
messages: Involved in acetate metabolism.
messages: The N-terminal region seems to be important for proper quaternary structure. The C-terminal region contains the substrate-binding site.

206403:YH65 RS07490
gene id: 206403:YH65_RS07490
uniprot id: A0A7U4RQZ5
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family.

206403:YH65 RS02600
gene id: 206403:YH65_RS02600
uniprot id: A0A7U4M060
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the urea transporter family.
messages: Cell membrane
messages: Membrane

206403:YH65 RS03040
gene id: 206403:YH65_RS03040
uniprot id: A0A7U4RQ55
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class II fructose-bisphosphate aldolase family.
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.
messages: Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.

206403:YH65 RS02635
gene id: 206403:YH65_RS02635
uniprot id: A0A7U4M2Z9
names: Subcellular Location Annotation
messages: Membrane

206403:YH65 RS06350
gene id: 206403:YH65_RS06350
uniprot id: A0A7U4M1E8
names: Subcellular Location Annotation
messages: Membrane

206403:YH65 RS00510
gene id: 206403:YH65_RS00510
uniprot id: A0A7U4LZF5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 2 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

206403:YH65 RS04240
gene id: 206403:YH65_RS04240
uniprot id: A0A7U4M0M0
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. NasA/NapA/NarB subfamily.

206403:YH65 RS10675
gene id: 206403:YH65_RS10675
uniprot id: A0A7U4M2R3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

206403:YH65 RS09450
gene id: 206403:YH65_RS09450
uniprot id: A0A7U4M2D1
names: Subcellular Location Annotation
messages: Membrane

206403:YH65 RS07915
gene id: 206403:YH65_RS07915
uniprot id: A0A7U4M1U5
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HMBS family.
messages: Binds 1 dipyrromethane group covalently.
messages: Monomer.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
messages: The porphobilinogen subunits are added to the dipyrromethane group.

206403:YH65 RS07075
gene id: 206403:YH65_RS07075
uniprot id: A0A7U4M1J9
names: Similarity
messages: Belongs to the bacterial sugar transferase family.

206403:YH65 RS09860
gene id: 206403:YH65_RS09860
uniprot id: A0A7U4M2H2
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

206403:YH65 RS01400
gene id: 206403:YH65_RS01400
uniprot id: A0A7U4LZS8
names: Subcellular Location Annotation
messages: Membrane

206403:YH65 RS03215
gene id: 206403:YH65_RS03215
uniprot id: A0A7U4RQ91
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

206403:YH65 RS07410
gene id: 206403:YH65_RS07410
uniprot id: A0A7U4RQY9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccD/PCCB family.
messages: Binds 1 zinc ion per subunit.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

206403:YH65 RS02195
gene id: 206403:YH65_RS02195
uniprot id: A0A7U4RQ59
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

206403:YH65 RS10590
gene id: 206403:YH65_RS10590
uniprot id: A0A7U4M2S4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

206403:YH65 RS09940
gene id: 206403:YH65_RS09940
uniprot id: A0A7U4M2H3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

206403:YH65 RS03765
gene id: 206403:YH65_RS03765
uniprot id: A0A7U4M0H4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the uroporphyrinogen decarboxylase family.
messages: Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

206403:YH65 RS10700
gene id: 206403:YH65_RS10700
uniprot id: A0A7U4M351
names: Function
names: Similarity
messages: Belongs to the ferredoxin thioredoxin reductase beta subunit family.
messages: Catalytic subunit of the ferredoxin-thioredoxin reductase (FTR), which catalyzes the two-electron reduction of thioredoxins by the electrons provided by reduced ferredoxin.

206403:YH65 RS02485
gene id: 206403:YH65_RS02485
uniprot id: A0A7U4M2Z5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the radical SAM superfamily. MqnC family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2).

206403:YH65 RS06010
gene id: 206403:YH65_RS06010
uniprot id: A0A7U4RQS5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

206403:YH65 RS00570
gene id: 206403:YH65_RS00570
uniprot id: A0A7U4RPW5
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

206403:YH65 RS10840
gene id: 206403:YH65_RS10840
uniprot id: A0A7U4RRJ0
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

206403:YH65 RS05115
gene id: 206403:YH65_RS05115
uniprot id: A0A7U4M0W9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the OMP decarboxylase family. Type 1 subfamily.
messages: Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
messages: Homodimer.

206403:YH65 RS09995
gene id: 206403:YH65_RS09995
uniprot id: A0A7U4M2J0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.
messages: Binds 1 S-adenosyl-L-methionine per subunit.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

206403:YH65 RS02875
gene id: 206403:YH65_RS02875
uniprot id: A0A7U4RQ41
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

206403:YH65 RS07940
gene id: 206403:YH65_RS07940
uniprot id: A0A7U4M1U4
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

206403:YH65 RS04200
gene id: 206403:YH65_RS04200
uniprot id: A0A7U4M0M3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OmpP1/FadL family.
messages: Cell outer membrane
messages: Membrane

206403:YH65 RS04990
gene id: 206403:YH65_RS04990
uniprot id: A0A7U4M0X0
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

206403:YH65 RS01840
gene id: 206403:YH65_RS01840
uniprot id: A0A7U4LZW2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ClpS family.
messages: Binds to the N-terminal domain of the chaperone ClpA.
messages: Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation.

206403:YH65 RS00615
gene id: 206403:YH65_RS00615
uniprot id: A0A7U4RPS2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methylthiotransferase family. MiaB subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
messages: Cytoplasm
messages: Monomer.

206403:YH65 RS09135
gene id: 206403:YH65_RS09135
uniprot id: A0A7U4M267
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial diacylglycerol kinase family.
messages: Membrane
messages: Mn(2+), Zn(2+), Cd(2+) and Co(2+) support activity to lesser extents.

206403:YH65 RS02575
gene id: 206403:YH65_RS02575
uniprot id: A0A7U4M073
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NhaD Na(+)/H(+) (TC 2.A.62) antiporter family.
messages: Membrane

206403:YH65 RS11090
gene id: 206403:YH65_RS11090
uniprot id: A0A7U4RRK3
names: Subcellular Location Annotation
messages: Membrane

206403:YH65 RS07000
gene id: 206403:YH65_RS07000
uniprot id: A0A7U4M1M0
names: Subcellular Location Annotation
messages: Membrane

206403:YH65 RS04440
gene id: 206403:YH65_RS04440
uniprot id: A0A7U4M0T8
names: Caution
names: Function
names: Similarity
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.
messages: Catalyzes the 2'-O methylation of guanosine at position 18 in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

206403:YH65 RS03280
gene id: 206403:YH65_RS03280
uniprot id: A0A7U4M0B7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

206403:YH65 RS00520
gene id: 206403:YH65_RS00520
uniprot id: A0A7U4LZJ4
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

206403:YH65 RS09330
gene id: 206403:YH65_RS09330
uniprot id: A0A7U4M2B6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

206403:YH65 RS05730
gene id: 206403:YH65_RS05730
uniprot id: A0A7U4M138
names: Similarity
messages: Belongs to the peptidase C40 family.

206403:YH65 RS02580
gene id: 206403:YH65_RS02580
uniprot id: A0A7U4RQ20
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

206403:YH65 RS02160
gene id: 206403:YH65_RS02160
uniprot id: A0A7U4RQ01
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2).

206403:YH65 RS01855
gene id: 206403:YH65_RS01855
uniprot id: A0A7U4RQ21
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 2 subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

206403:YH65 RS00890
gene id: 206403:YH65_RS00890
uniprot id: A0A7U4RPT4
names: Function
names: PTM
names: Similarity
messages: An intermediate of this reaction is the autophosphorylated ppk in which a phosphate is covalently linked to a histidine residue through a N-P bond.
messages: Belongs to the polyphosphate kinase 1 (PPK1) family.
messages: Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP).

206403:YH65 RS04875
gene id: 206403:YH65_RS04875
uniprot id: A0A7U4M0U0
names: Similarity
messages: Belongs to the prokaryotic/mitochondrial release factor family.

206403:YH65 RS07230
gene id: 206403:YH65_RS07230
uniprot id: A0A7U4M346
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

206403:YH65 RS02375
gene id: 206403:YH65_RS02375
uniprot id: A0A7U4RQ52
names: Function
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. Fucose synthase subfamily.
messages: Catalyzes the two-step NADP-dependent conversion of GDP-4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction.

206403:YH65 RS05225
gene id: 206403:YH65_RS05225
uniprot id: A0A7U4RQI6
names: Similarity
messages: Belongs to the DEAD box helicase family.

206403:YH65 RS02630
gene id: 206403:YH65_RS02630
uniprot id: A0A7U4RQ71
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the heat shock protein 90 family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Molecular chaperone. Has ATPase activity.

206403:YH65 RS07870
gene id: 206403:YH65_RS07870
uniprot id: A0A7U4M1U7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

206403:YH65 RS02730
gene id: 206403:YH65_RS02730
uniprot id: A0A7U4M058
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

206403:YH65 RS02470
gene id: 206403:YH65_RS02470
uniprot id: A0A7U4M018
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KdsA family.
messages: Cytoplasm

206403:YH65 RS10085
gene id: 206403:YH65_RS10085
uniprot id: A0A7U4M2L6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

206403:YH65 RS05780
gene id: 206403:YH65_RS05780
uniprot id: A0A7U4M140
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruD family.
messages: Responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs.

206403:YH65 RS10355
gene id: 206403:YH65_RS10355
uniprot id: A0A7U4M2M6
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

206403:YH65 RS09200
gene id: 206403:YH65_RS09200
uniprot id: A0A7U4M292
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

206403:YH65 RS01710
gene id: 206403:YH65_RS01710
uniprot id: A0A7U4LZV1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

206403:YH65 RS01325
gene id: 206403:YH65_RS01325
uniprot id: A0A7U4LZP1
names: Similarity
messages: Belongs to the UPF0047 family.

206403:YH65 RS03565
gene id: 206403:YH65_RS03565
uniprot id: A0A7U4M0F1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer.

206403:YH65 RS08035
gene id: 206403:YH65_RS08035
uniprot id: A0A7U4RR23
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

206403:YH65 RS01310
gene id: 206403:YH65_RS01310
uniprot id: A0A7U4LZR0
names: Cofactor
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Binds 1 [3Fe-4S] cluster.
messages: Binds 1 [4Fe-4S] cluster.

206403:YH65 RS07160
gene id: 206403:YH65_RS07160
uniprot id: A0A7U4RQX9
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

206403:YH65 RS09205
gene id: 206403:YH65_RS09205
uniprot id: A0A7U4M2B0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Cell membrane
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

206403:YH65 RS04155
gene id: 206403:YH65_RS04155
uniprot id: A0A7U4RQF2
names: Subcellular Location Annotation
messages: Membrane

206403:YH65 RS07275
gene id: 206403:YH65_RS07275
uniprot id: A0A7U4M1M3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

206403:YH65 RS06715
gene id: 206403:YH65_RS06715
uniprot id: A0A7U4M1G0
names: Similarity
messages: Belongs to the glycosyl hydrolase 20 family.

206403:YH65 RS01745
gene id: 206403:YH65_RS01745
uniprot id: A0A7U4LZX0
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Monomer.