2052056:CTZ24 RS03285
gene id: 2052056:CTZ24_RS03285
uniprot id: A0A6I6AQE8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

2052056:CTZ24 RS13660
gene id: 2052056:CTZ24_RS13660
uniprot id: A0A6I6AWA8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PNP synthase family.
messages: Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.
messages: Cytoplasm
messages: Homooctamer; tetramer of dimers.

2052056:CTZ24 RS14870
gene id: 2052056:CTZ24_RS14870
uniprot id: A0A6I6AZ88
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Cell membrane
messages: In the C-terminal section; belongs to the complex I 49 kDa subunit family.
messages: In the N-terminal section; belongs to the complex I 30 kDa subunit family.
messages: NDH-1 is composed of 13 different subunits. Subunits NuoB, CD, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

2052056:CTZ24 RS10645
gene id: 2052056:CTZ24_RS10645
uniprot id: A0A6I6AWU9
names: Subcellular Location Annotation
messages: Membrane

2052056:CTZ24 RS03275
gene id: 2052056:CTZ24_RS03275
uniprot id: A0A6I6AQW0
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

2052056:CTZ24 RS11130
gene id: 2052056:CTZ24_RS11130
uniprot id: A0A6I6AUS5
names: Similarity
messages: Belongs to the MipA/OmpV family.

2052056:CTZ24 RS16830
gene id: 2052056:CTZ24_RS16830
uniprot id: A0A6I6AXW7
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

2052056:CTZ24 RS10330
gene id: 2052056:CTZ24_RS10330
uniprot id: A0A6I6ASU6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. SotB (TC 2.A.1.2) family.
messages: Cell membrane
messages: Involved in the efflux of sugars. The physiological role may be the reduction of the intracellular concentration of toxic sugars or sugar metabolites.
messages: Membrane

2052056:CTZ24 RS03360
gene id: 2052056:CTZ24_RS03360
uniprot id: A0A6I6ASQ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Membrane

2052056:CTZ24 RS08575
gene id: 2052056:CTZ24_RS08575
uniprot id: A0A6I6ASH6
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

2052056:CTZ24 RS19160
gene id: 2052056:CTZ24_RS19160
uniprot id: A0A6I6AZ37
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KdpC family.
messages: Cell membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

2052056:CTZ24 RS13325
gene id: 2052056:CTZ24_RS13325
uniprot id: A0A6I6AUD9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ElaB/YgaM/YqjD family.
messages: Cell inner membrane
messages: Membrane

2052056:CTZ24 RS06775
gene id: 2052056:CTZ24_RS06775
uniprot id: A0A6I6AUR8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycyl radical enzyme (GRE) family. PFL subfamily.
messages: Cytoplasm
messages: Homodimer.

2052056:CTZ24 RS10930
gene id: 2052056:CTZ24_RS10930
uniprot id: A0A6I6AXX1
names: Similarity
messages: Belongs to the YciI family.

2052056:CTZ24 RS04235
gene id: 2052056:CTZ24_RS04235
uniprot id: A0A6I6AR44
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

2052056:CTZ24 RS06580
gene id: 2052056:CTZ24_RS06580
uniprot id: A0A6I6ASG7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAE transporter (TC 2.A.81) family. YbjL subfamily.
messages: Cell membrane

2052056:CTZ24 RS00035
gene id: 2052056:CTZ24_RS00035
uniprot id: A0A6I6ANS7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Part of the phosphate (Pho) regulon, which plays a key role in phosphate homeostasis. PhoU is essential for the repression of the Pho regulon at high phosphate conditions.

2052056:CTZ24 RS04800
gene id: 2052056:CTZ24_RS04800
uniprot id: A0A6I6AUW7
names: Subcellular Location Annotation
messages: Membrane

2052056:CTZ24 RS07815
gene id: 2052056:CTZ24_RS07815
uniprot id: A0A6I6AS46
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of a number of rings mounted on a central rod.

2052056:CTZ24 RS12735
gene id: 2052056:CTZ24_RS12735
uniprot id: A0A6I6B263
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm

2052056:CTZ24 RS12220
gene id: 2052056:CTZ24_RS12220
uniprot id: A0A6I6ATT7
names: Subcellular Location Annotation
messages: Membrane

2052056:CTZ24 RS05460
gene id: 2052056:CTZ24_RS05460
uniprot id: A0A6I6B2F2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEDS family. MrdB/RodA subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Peptidoglycan polymerase that is essential for cell wall elongation.

2052056:CTZ24 RS24815
gene id: 2052056:CTZ24_RS24815
uniprot id: A0A6I6B8S3
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

2052056:CTZ24 RS13580
gene id: 2052056:CTZ24_RS13580
uniprot id: A0A6I6B3H3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2052056:CTZ24 RS08980
gene id: 2052056:CTZ24_RS08980
uniprot id: A0A6I6B0N8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SlyA family.
messages: Homodimer.
messages: Transcription regulator that can specifically activate or repress expression of target genes.

2052056:CTZ24 RS06130
gene id: 2052056:CTZ24_RS06130
uniprot id: A0A6I6AS11
names: Similarity
messages: Belongs to the peptidase S11 family.

2052056:CTZ24 RS06015
gene id: 2052056:CTZ24_RS06015
uniprot id: A0A6I6AV80
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gluconeogenesis factor family.
messages: Cytoplasm
messages: Required for morphogenesis under gluconeogenic growth conditions.

2052056:CTZ24 RS01855
gene id: 2052056:CTZ24_RS01855
uniprot id: A0A6I6ARX3
names: Subcellular Location Annotation
messages: Membrane

2052056:CTZ24 RS09210
gene id: 2052056:CTZ24_RS09210
uniprot id: A0A6I6ASA9
names: Similarity
messages: Belongs to the ABC transporter superfamily. Drug exporter-2 (TC 3.A.1.117) family.

2052056:CTZ24 RS07685
gene id: 2052056:CTZ24_RS07685
uniprot id: A0A6I6B2G7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acyltransferase 3 family. OpgC subfamily.
messages: Cell membrane
messages: Necessary for the succinyl substitution of periplasmic glucans. Could catalyze the transfer of succinyl residues from the cytoplasmic side of the membrane to the nascent glucan backbones on the periplasmic side of the membrane.

2052056:CTZ24 RS14710
gene id: 2052056:CTZ24_RS14710
uniprot id: A0A6I6B403
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Membrane

2052056:CTZ24 RS13615
gene id: 2052056:CTZ24_RS13615
uniprot id: A0A6I6AUU9
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

2052056:CTZ24 RS05515
gene id: 2052056:CTZ24_RS05515
uniprot id: A0A6I6AYK3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

2052056:CTZ24 RS26095
gene id: 2052056:CTZ24_RS26095
uniprot id: A0A6I6B1K9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

2052056:CTZ24 RS18890
gene id: 2052056:CTZ24_RS18890
uniprot id: A0A6I6B1R6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

2052056:CTZ24 RS17745
gene id: 2052056:CTZ24_RS17745
uniprot id: A0A6I6AYE5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SIS family. DiaA subfamily.
messages: Homotetramer; dimer of dimers.
messages: Required for the timely initiation of chromosomal replication via direct interactions with the DnaA initiator protein.

2052056:CTZ24 RS16860
gene id: 2052056:CTZ24_RS16860
uniprot id: A0A6I6AW25
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LolB family.
messages: Cell outer membrane
messages: Membrane
messages: Monomer.
messages: Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein.

2052056:CTZ24 RS06770
gene id: 2052056:CTZ24_RS06770
uniprot id: A0A6I6AVW9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Activation of pyruvate formate-lyase 1 under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.
messages: Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.
messages: Belongs to the organic radical-activating enzymes family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm

2052056:CTZ24 RS17615
gene id: 2052056:CTZ24_RS17615
uniprot id: A0A6I6AYC6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2052056:CTZ24 RS02815
gene id: 2052056:CTZ24_RS02815
uniprot id: A0A6I6ASG3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell membrane
messages: Membrane

2052056:CTZ24 RS12885
gene id: 2052056:CTZ24_RS12885
uniprot id: A0A6I6AVW0
names: Function
names: Similarity
messages: Belongs to the UxaA family.
messages: Catalyzes the dehydration of galactarate to form 5-dehydro-4-deoxy-D-glucarate (5-KDG).

2052056:CTZ24 RS01175
gene id: 2052056:CTZ24_RS01175
uniprot id: A0A6I6ARD5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Rsd/AlgQ family.
messages: Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase.
messages: Cytoplasm
messages: Interacts with RpoD.

2052056:CTZ24 RS00485
gene id: 2052056:CTZ24_RS00485
uniprot id: A0A6I6ASI0
names: Subcellular Location Annotation
names: Subunit
messages: Cell inner membrane
messages: Homodimer.
messages: Membrane

2052056:CTZ24 RS04930
gene id: 2052056:CTZ24_RS04930
uniprot id: A0A6I6ARP0
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

2052056:CTZ24 RS08715
gene id: 2052056:CTZ24_RS08715
uniprot id: A0A6I6AS40
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

2052056:CTZ24 RS19380
gene id: 2052056:CTZ24_RS19380
uniprot id: A0A6I6B6M1
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

2052056:CTZ24 RS03895
gene id: 2052056:CTZ24_RS03895
uniprot id: A0A6I6APL5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with (2E,6E)-farnesyl diphosphate (E,E-FPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E,38E)-undecaprenyl diphosphate (di-trans,octa-cis-UPP). UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide.
messages: Homodimer.

2052056:CTZ24 RS11345
gene id: 2052056:CTZ24_RS11345
uniprot id: A0A6I6AUW9
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Membrane

2052056:CTZ24 RS05535
gene id: 2052056:CTZ24_RS05535
uniprot id: A0A6I6AQK6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

2052056:CTZ24 RS02285
gene id: 2052056:CTZ24_RS02285
uniprot id: A0A6I6ANU0
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Alleviates ribosome stalling that occurs when 3 or more consecutive Pro residues or the sequence PPG is present in a protein, possibly by augmenting the peptidyl transferase activity of the ribosome. Modification of Lys-34 is required for alleviation.
messages: May be beta-lysylated on the epsilon-amino group of Lys-34 by the combined action of EpmA and EpmB, and then hydroxylated on the C5 position of the same residue by EpmC (if this protein is present). Lysylation is critical for the stimulatory effect of EF-P on peptide-bond formation. The lysylation moiety may extend toward the peptidyltransferase center and stabilize the terminal 3-CCA end of the tRNA. Hydroxylation of the C5 position on Lys-34 may allow additional potential stabilizing hydrogen-bond interactions with the P-tRNA.

2052056:CTZ24 RS15470
gene id: 2052056:CTZ24_RS15470
uniprot id: A0A6I6AVC8
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. MdtC subfamily.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of a tripartite efflux system composed of MdtA, MdtB and MdtC. MdtC forms a heteromultimer with MdtB.

2052056:CTZ24 RS01980
gene id: 2052056:CTZ24_RS01980
uniprot id: A0A6I6AT32
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2052056:CTZ24 RS19560
gene id: 2052056:CTZ24_RS19560
uniprot id: A0A6I6B1Q8
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

2052056:CTZ24 RS05425
gene id: 2052056:CTZ24_RS05425
uniprot id: A0A6I6AQI8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. Drug exporter-2 (TC 3.A.1.117) family.
messages: Cell inner membrane
messages: Membrane

2052056:CTZ24 RS15670
gene id: 2052056:CTZ24_RS15670
uniprot id: A0A6I6AVI7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

2052056:CTZ24 RS02700
gene id: 2052056:CTZ24_RS02700
uniprot id: A0A6I6AWQ0
names: Similarity
messages: Belongs to the UPF0306 family.

2052056:CTZ24 RS02525
gene id: 2052056:CTZ24_RS02525
uniprot id: A0A6I6ATQ0
names: Similarity
messages: Belongs to the ABC transporter superfamily. Drug exporter-2 (TC 3.A.1.117) family.

2052056:CTZ24 RS18840
gene id: 2052056:CTZ24_RS18840
uniprot id: A0A6I6AYZ2
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.

2052056:CTZ24 RS15065
gene id: 2052056:CTZ24_RS15065
uniprot id: A0A6I6AZY1
names: Cofactor
messages: Binds 1 Fe(2+) ion per subunit.

2052056:CTZ24 RS19955
gene id: 2052056:CTZ24_RS19955
uniprot id: A0A6I6AZH0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

2052056:CTZ24 RS02370
gene id: 2052056:CTZ24_RS02370
uniprot id: A0A6I6AS79
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RapZ-like family. RapZ subfamily.
messages: Homotrimer.
messages: Modulates the synthesis of GlmS, by affecting the processing and stability of the regulatory small RNA GlmZ. When glucosamine-6-phosphate (GlcN6P) concentrations are high in the cell, RapZ binds GlmZ and targets it to cleavage by RNase E. Consequently, GlmZ is inactivated and unable to activate GlmS synthesis. Under low GlcN6P concentrations, RapZ is sequestered and inactivated by an other regulatory small RNA, GlmY, preventing GlmZ degradation and leading to synthesis of GlmS.

2052056:CTZ24 RS15270
gene id: 2052056:CTZ24_RS15270
uniprot id: A0A6I6AZF3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

2052056:CTZ24 RS14030
gene id: 2052056:CTZ24_RS14030
uniprot id: A0A6I6AWA4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48 family. BepA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Functions as both a chaperone and a metalloprotease. Maintains the integrity of the outer membrane by promoting either the assembly or the elimination of outer membrane proteins, depending on their folding state.
messages: Periplasm

2052056:CTZ24 RS08115
gene id: 2052056:CTZ24_RS08115
uniprot id: A0A6I6AS98
names: Cofactor
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

2052056:CTZ24 RS06835
gene id: 2052056:CTZ24_RS06835
uniprot id: A0A6I6AR20
names: Similarity
messages: Belongs to the UPF0434 family.

2052056:CTZ24 RS18765
gene id: 2052056:CTZ24_RS18765
uniprot id: A0A6I6AX27
names: Subcellular Location Annotation
messages: Cell inner membrane

2052056:CTZ24 RS09765
gene id: 2052056:CTZ24_RS09765
uniprot id: A0A6I6ATX9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2052056:CTZ24 RS07825
gene id: 2052056:CTZ24_RS07825
uniprot id: A0A6I6AZG9
names: Function
names: Similarity
messages: Belongs to the FlgD family.
messages: Required for flagellar hook formation. May act as a scaffolding protein.

2052056:CTZ24 RS11300
gene id: 2052056:CTZ24_RS11300
uniprot id: A0A6I6AUU2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0266 family.
messages: Cell membrane
messages: Membrane

2052056:CTZ24 RS18340
gene id: 2052056:CTZ24_RS18340
uniprot id: A0A6I6AWW0
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

2052056:CTZ24 RS19025
gene id: 2052056:CTZ24_RS19025
uniprot id: A0A6I6B1F6
names: Subcellular Location Annotation
messages: Membrane

2052056:CTZ24 RS23520
gene id: 2052056:CTZ24_RS23520
uniprot id: A0A6I6B502
names: Similarity
messages: Belongs to the Hok/Gef family.

2052056:CTZ24 RS05440
gene id: 2052056:CTZ24_RS05440
uniprot id: A0A6I6ARW4
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LipB family.
messages: Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
messages: Cytoplasm
messages: In the reaction, the free carboxyl group of octanoic acid is attached via an amide linkage to the epsilon-amino group of a specific lysine residue of lipoyl domains of lipoate-dependent enzymes.

2052056:CTZ24 RS15800
gene id: 2052056:CTZ24_RS15800
uniprot id: A0A6I6AVW5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA gyrase inhibitor family.
messages: Cytoplasm
messages: Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell.
messages: Interacts with DNA gyrase.

2052056:CTZ24 RS12085
gene id: 2052056:CTZ24_RS12085
uniprot id: A0A6I6B1N9
names: Caution
names: Function
names: Similarity
messages: Belongs to the UbiX/PAD1 family.
messages: Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2052056:CTZ24 RS03440
gene id: 2052056:CTZ24_RS03440
uniprot id: A0A6I6AQ46
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsL family.
messages: Cell inner membrane
messages: Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.
messages: Membrane
messages: Part of a complex composed of FtsB, FtsL and FtsQ.

2052056:CTZ24 RS10670
gene id: 2052056:CTZ24_RS10670
uniprot id: A0A6I6AUH3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

2052056:CTZ24 RS06050
gene id: 2052056:CTZ24_RS06050
uniprot id: A0A6I6AUC6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

2052056:CTZ24 RS18450
gene id: 2052056:CTZ24_RS18450
uniprot id: A0A6I6B1K3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

2052056:CTZ24 RS13210
gene id: 2052056:CTZ24_RS13210
uniprot id: A0A6I6AYC4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamD family.
messages: Cell outer membrane
messages: Part of the Bam complex, which is composed of the outer membrane protein BamA, and four lipoproteins BamB, BamC, BamD and BamE.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. Constitutes, with BamA, the core component of the assembly machinery.

2052056:CTZ24 RS17890
gene id: 2052056:CTZ24_RS17890
uniprot id: A0A6I6B1C8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inositol monophosphatase superfamily. CysQ family.
messages: Cell inner membrane
messages: Converts adenosine-3',5'-bisphosphate (PAP) to AMP.

2052056:CTZ24 RS00605
gene id: 2052056:CTZ24_RS00605
uniprot id: A0A6I6AR48
names: Similarity
messages: Belongs to the ABC transporter superfamily. Drug exporter-2 (TC 3.A.1.117) family.

2052056:CTZ24 RS11250
gene id: 2052056:CTZ24_RS11250
uniprot id: A0A6I6AUT0
names: Similarity
messages: Belongs to the RutC family.

2052056:CTZ24 RS23495
gene id: 2052056:CTZ24_RS23495
uniprot id: A0A6I6B217
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

2052056:CTZ24 RS07975
gene id: 2052056:CTZ24_RS07975
uniprot id: A0A6I6AZJ8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LpoB family.
messages: Cell outer membrane
messages: Interacts with PBP1b.
messages: Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b).

2052056:CTZ24 RS16995
gene id: 2052056:CTZ24_RS16995
uniprot id: A0A6I6AY03
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.
messages: Cell membrane
messages: Membrane
messages: Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

2052056:CTZ24 RS03930
gene id: 2052056:CTZ24_RS03930
uniprot id: A0A6I6AXI4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxA subfamily.
messages: Cytoplasm
messages: Homotrimer.
messages: Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

2052056:CTZ24 RS19290
gene id: 2052056:CTZ24_RS19290
uniprot id: A0A6I6B1L1
names: Similarity
messages: Belongs to the ABC transporter superfamily. Drug exporter-2 (TC 3.A.1.117) family.

2052056:CTZ24 RS15015
gene id: 2052056:CTZ24_RS15015
uniprot id: A0A6I6AWY4
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Autophosphorylated. Activation probably requires a transfer of a phosphate group from a His in the transmitter domain to an Asp in the receiver domain.
messages: Belongs to the RcsC family.
messages: Cell inner membrane
messages: Component of the Rcs signaling system, which controls transcription of numerous genes. RcsC functions as a membrane-associated protein kinase that phosphorylates RcsD in response to environmental signals. The phosphoryl group is then transferred to the response regulator RcsB.
messages: Interacts with RcsD.

2052056:CTZ24 RS09200
gene id: 2052056:CTZ24_RS09200
uniprot id: A0A6I6AW28
names: Similarity
messages: Belongs to the Hha/YmoA/Cnu family.

2052056:CTZ24 RS07895
gene id: 2052056:CTZ24_RS07895
uniprot id: A0A6I6ARQ9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsX family.
messages: Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
messages: Cytoplasm
messages: Homodimer. Probably interacts with PlsY.

2052056:CTZ24 RS14605
gene id: 2052056:CTZ24_RS14605
uniprot id: A0A6I6B307
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Reduced FMN (FMNH(2)).

2052056:CTZ24 RS09420
gene id: 2052056:CTZ24_RS09420
uniprot id: A0A6I6B7B4
names: Function
names: Similarity
messages: Belongs to the PqqA family.
messages: Required for coenzyme pyrroloquinoline quinone (PQQ) biosynthesis. PQQ is probably formed by cross-linking a specific glutamate to a specific tyrosine residue and excising these residues from the peptide.

2052056:CTZ24 RS19420
gene id: 2052056:CTZ24_RS19420
uniprot id: A0A6I6AXN9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2052056:CTZ24 RS02730
gene id: 2052056:CTZ24_RS02730
uniprot id: A0A6I6AQN0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PyrI family.
messages: Binds 1 zinc ion per subunit.
messages: Contains catalytic and regulatory chains.
messages: Involved in allosteric regulation of aspartate carbamoyltransferase.

2052056:CTZ24 RS05165
gene id: 2052056:CTZ24_RS05165
uniprot id: A0A6I6AQV9
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

2052056:CTZ24 RS06430
gene id: 2052056:CTZ24_RS06430
uniprot id: A0A6I6ASE0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

2052056:CTZ24 RS18230
gene id: 2052056:CTZ24_RS18230
uniprot id: A0A6I6B1H2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

2052056:CTZ24 RS11170
gene id: 2052056:CTZ24_RS11170
uniprot id: A0A6I6AT75
names: Function
names: Similarity
messages: Belongs to the DadA oxidoreductase family.
messages: Oxidative deamination of D-amino acids.

2052056:CTZ24 RS15540
gene id: 2052056:CTZ24_RS15540
uniprot id: A0A6I6AVS0
names: Similarity
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.

2052056:CTZ24 RS15810
gene id: 2052056:CTZ24_RS15810
uniprot id: A0A6I6B3I5
names: Similarity
messages: Belongs to the UPF0265 family.

2052056:CTZ24 RS05810
gene id: 2052056:CTZ24_RS05810
uniprot id: A0A6I6AYR0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Pal lipoprotein family.
messages: Cell outer membrane
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

2052056:CTZ24 RS03290
gene id: 2052056:CTZ24_RS03290
uniprot id: A0A6I6AWW4
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

2052056:CTZ24 RS04995
gene id: 2052056:CTZ24_RS04995
uniprot id: A0A6I6AQT9
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

2052056:CTZ24 RS19435
gene id: 2052056:CTZ24_RS19435
uniprot id: A0A6I6B6N2
names: Function
names: Similarity
messages: Acts on leucine, isoleucine and valine.
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

2052056:CTZ24 RS25550
gene id: 2052056:CTZ24_RS25550
uniprot id: A0A6I6B992
names: Similarity
messages: Belongs to the nitrile hydratase subunit alpha family.

2052056:CTZ24 RS03740
gene id: 2052056:CTZ24_RS03740
uniprot id: A0A6I6AU27
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

2052056:CTZ24 RS17910
gene id: 2052056:CTZ24_RS17910
uniprot id: A0A6I6AYH1
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

2052056:CTZ24 RS14705
gene id: 2052056:CTZ24_RS14705
uniprot id: A0A6I6B322
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2052056:CTZ24 RS05465
gene id: 2052056:CTZ24_RS05465
uniprot id: A0A6I6AYJ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transpeptidase family. MrdA subfamily.
messages: Catalyzes cross-linking of the peptidoglycan cell wall.
messages: Cell inner membrane

2052056:CTZ24 RS02060
gene id: 2052056:CTZ24_RS02060
uniprot id: A0A6I6AWA2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

2052056:CTZ24 RS16605
gene id: 2052056:CTZ24_RS16605
uniprot id: A0A6I6AVX4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliM family.
messages: Cell inner membrane
messages: FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
messages: Membrane

2052056:CTZ24 RS08920
gene id: 2052056:CTZ24_RS08920
uniprot id: A0A6I6B039
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase T family.
messages: Binds two Mg(2+) per subunit. The active form of the enzyme binds two Mg(2+) ions in its active site. The first Mg(2+) forms only one salt bridge with the protein.
messages: Homodimer.
messages: Trims short 3' overhangs of a variety of RNA species, leaving a one or two nucleotide 3' overhang. Responsible for the end-turnover of tRNA: specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis.

2052056:CTZ24 RS02210
gene id: 2052056:CTZ24_RS02210
uniprot id: A0A6I6AWD3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

2052056:CTZ24 RS04755
gene id: 2052056:CTZ24_RS04755
uniprot id: A0A6I6ATN0
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

2052056:CTZ24 RS01335
gene id: 2052056:CTZ24_RS01335
uniprot id: A0A6I6AVT6
names: Function
names: Similarity
messages: Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis.
messages: Belongs to the glycogen phosphorylase family.
messages: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.

2052056:CTZ24 RS08640
gene id: 2052056:CTZ24_RS08640
uniprot id: A0A6I6AZY7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Bcr/CmlA family.
messages: Cell inner membrane
messages: Membrane

2052056:CTZ24 RS09460
gene id: 2052056:CTZ24_RS09460
uniprot id: A0A6I6B0Y4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the quinone-dependent D-lactate dehydrogenase family.
messages: Catalyzes the oxidation of D-lactate to pyruvate.
messages: Cell inner membrane

2052056:CTZ24 RS03195
gene id: 2052056:CTZ24_RS03195
uniprot id: A0A6I6AU09
names: Similarity
names: Subunit
messages: Homotetramer.
messages: In the C-terminal section; belongs to the homoserine dehydrogenase family.
messages: In the N-terminal section; belongs to the aspartokinase family.

2052056:CTZ24 RS04980
gene id: 2052056:CTZ24_RS04980
uniprot id: A0A6I6AQ61
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

2052056:CTZ24 RS04705
gene id: 2052056:CTZ24_RS04705
uniprot id: A0A6I6ATM1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

2052056:CTZ24 RS18285
gene id: 2052056:CTZ24_RS18285
uniprot id: A0A6I6B112
names: Similarity
messages: Belongs to the Smg family.

2052056:CTZ24 RS05475
gene id: 2052056:CTZ24_RS05475
uniprot id: A0A6I6AU10
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein uL14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein uL14 (rplN).

2052056:CTZ24 RS05770
gene id: 2052056:CTZ24_RS05770
uniprot id: A0A6I6AU76
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

2052056:CTZ24 RS03420
gene id: 2052056:CTZ24_RS03420
uniprot id: A0A6I6AP69
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

2052056:CTZ24 RS24785
gene id: 2052056:CTZ24_RS24785
uniprot id: A0A6I6B5I0
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

2052056:CTZ24 RS13650
gene id: 2052056:CTZ24_RS13650
uniprot id: A0A6I6AUH5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer.

2052056:CTZ24 RS00335
gene id: 2052056:CTZ24_RS00335
uniprot id: A0A6I6AS80
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the xylose isomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.

2052056:CTZ24 RS24995
gene id: 2052056:CTZ24_RS24995
uniprot id: A0A6I6B5M0
names: Similarity
messages: Belongs to the NifX/NifY family.

2052056:CTZ24 RS05175
gene id: 2052056:CTZ24_RS05175
uniprot id: A0A6I6AXZ5
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

2052056:CTZ24 RS12195
gene id: 2052056:CTZ24_RS12195
uniprot id: A0A6I6AVB6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Fe(2+)-trafficking protein family.
messages: Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes.
messages: Monomer.

2052056:CTZ24 RS04185
gene id: 2052056:CTZ24_RS04185
uniprot id: A0A6I6AR15
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAD-like hydrolase superfamily. MasA/MtnC family.
messages: Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene).
messages: Binds 1 Mg(2+) ion per subunit.
messages: Monomer.

2052056:CTZ24 RS03115
gene id: 2052056:CTZ24_RS03115
uniprot id: A0A6I6APZ3
names: Similarity
messages: Belongs to the ABC transporter superfamily. Drug exporter-2 (TC 3.A.1.117) family.

2052056:CTZ24 RS01240
gene id: 2052056:CTZ24_RS01240
uniprot id: A0A6I6AN61
names: Cofactor
messages: Can also use Mn(2+) ion.

2052056:CTZ24 RS09345
gene id: 2052056:CTZ24_RS09345
uniprot id: A0A6I6AZT8
names: Similarity
messages: Belongs to the barstar family.

2052056:CTZ24 RS20145
gene id: 2052056:CTZ24_RS20145
uniprot id: A0A6I6B2F8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase delta chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

2052056:CTZ24 RS06710
gene id: 2052056:CTZ24_RS06710
uniprot id: A0A6I6AYW5
names: Similarity
messages: Belongs to the ClpA/ClpB family.

2052056:CTZ24 RS14535
gene id: 2052056:CTZ24_RS14535
uniprot id: A0A6I6AWR5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmD/CycX/HelD family.
messages: Cell inner membrane
messages: Membrane
messages: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.

2052056:CTZ24 RS04005
gene id: 2052056:CTZ24_RS04005
uniprot id: A0A6I6AU67
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nlpA lipoprotein family.
messages: Membrane

2052056:CTZ24 RS19600
gene id: 2052056:CTZ24_RS19600
uniprot id: A0A6I6B586
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RraA family.
messages: Cytoplasm
messages: Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome.
messages: Homotrimer. Binds to both RNA-binding sites in the C-terminal region of Rne and to RhlB.

2052056:CTZ24 RS03160
gene id: 2052056:CTZ24_RS03160
uniprot id: A0A6I6AQU1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the YjjX NTPase family.
messages: Binds 1 divalent metal cation per subunit; can use either Mg(2+) or Mn(2+).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA/RNA precursor pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

2052056:CTZ24 RS08820
gene id: 2052056:CTZ24_RS08820
uniprot id: A0A6I6AVW3
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

2052056:CTZ24 RS24915
gene id: 2052056:CTZ24_RS24915
uniprot id: A0A6I6B145
names: Subcellular Location Annotation
messages: Membrane

2052056:CTZ24 RS08885
gene id: 2052056:CTZ24_RS08885
uniprot id: A0A6I6AVX2
names: Similarity
messages: Belongs to the CFA/CMAS family.

2052056:CTZ24 RS18380
gene id: 2052056:CTZ24_RS18380
uniprot id: A0A6I6B1L6
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

2052056:CTZ24 RS15365
gene id: 2052056:CTZ24_RS15365
uniprot id: A0A6I6B020
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.

2052056:CTZ24 RS14405
gene id: 2052056:CTZ24_RS14405
uniprot id: A0A6I6AWP6
names: Similarity
messages: Belongs to the shaker potassium channel beta subunit family.

2052056:CTZ24 RS03500
gene id: 2052056:CTZ24_RS03500
uniprot id: A0A6I6AX10
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

2052056:CTZ24 RS07040
gene id: 2052056:CTZ24_RS07040
uniprot id: A0A6I6AR59
names: Function
names: Similarity
messages: Belongs to the methylglyoxal synthase family.
messages: Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate.

2052056:CTZ24 RS10600
gene id: 2052056:CTZ24_RS10600
uniprot id: A0A6I6ASZ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Cell inner membrane
messages: Membrane
messages: Zinc transporter. Acts as a Zn(2+):proton symporter, which likely mediates zinc ion uptake.

2052056:CTZ24 RS19055
gene id: 2052056:CTZ24_RS19055
uniprot id: A0A6I6AXI2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal stress protein B family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

2052056:CTZ24 RS03880
gene id: 2052056:CTZ24_RS03880
uniprot id: A0A6I6AUD5
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by GTP. Inhibited by UTP.
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2052056:CTZ24 RS01745
gene id: 2052056:CTZ24_RS01745
uniprot id: A0A6I6ATA6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family. GltP subfamily.
messages: Catalyzes the proton-dependent transport of glutamate and aspartate.
messages: Cell inner membrane
messages: Membrane

2052056:CTZ24 RS05610
gene id: 2052056:CTZ24_RS05610
uniprot id: A0A6I6AVD0
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Allosterically activated by N-acetylglucosamine 6-phosphate (GlcNAc6P).
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily.
messages: Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.
messages: Homohexamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2052056:CTZ24 RS13320
gene id: 2052056:CTZ24_RS13320
uniprot id: A0A6I6AYE6
names: Function
names: Similarity
messages: Belongs to the glutaredoxin family.
messages: Electron transport system for the ribonucleotide reductase system NrdEF.

2052056:CTZ24 RS06750
gene id: 2052056:CTZ24_RS06750
uniprot id: A0A6I6ARM4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LolA family.
messages: Monomer.
messages: Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane).
messages: Periplasm

2052056:CTZ24 RS03555
gene id: 2052056:CTZ24_RS03555
uniprot id: A0A6I6AX89
names: Subcellular Location Annotation
messages: Membrane

2052056:CTZ24 RS08535
gene id: 2052056:CTZ24_RS08535
uniprot id: A0A6I6AZW6
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CheB family.
messages: Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.
messages: Cytoplasm
messages: Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
messages: Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity.

2052056:CTZ24 RS00755
gene id: 2052056:CTZ24_RS00755
uniprot id: A0A6I6AR76
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.

2052056:CTZ24 RS19275
gene id: 2052056:CTZ24_RS19275
uniprot id: A0A6I6B526
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

2052056:CTZ24 RS15250
gene id: 2052056:CTZ24_RS15250
uniprot id: A0A6I6AX22
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the AP endonuclease 2 family.
messages: Binds 3 Zn(2+) ions.
messages: Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate.

2052056:CTZ24 RS12615
gene id: 2052056:CTZ24_RS12615
uniprot id: A0A6I6AUD3
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane.

2052056:CTZ24 RS04850
gene id: 2052056:CTZ24_RS04850
uniprot id: A0A6I6AY73
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

2052056:CTZ24 RS05445
gene id: 2052056:CTZ24_RS05445
uniprot id: A0A6I6AQZ7
names: Similarity
messages: Belongs to the UPF0250 family.

2052056:CTZ24 RS12205
gene id: 2052056:CTZ24_RS12205
uniprot id: A0A6I6B2L2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
messages: Monomer.

2052056:CTZ24 RS07840
gene id: 2052056:CTZ24_RS07840
uniprot id: A0A6I6AVD3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

2052056:CTZ24 RS19590
gene id: 2052056:CTZ24_RS19590
uniprot id: A0A6I6AXR2
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: Allosterically activated by HslU binding.
messages: Belongs to the peptidase T1B family. HslV subfamily.
messages: Cytoplasm
messages: Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.

2052056:CTZ24 RS08055
gene id: 2052056:CTZ24_RS08055
uniprot id: A0A6I6AWB3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

2052056:CTZ24 RS06705
gene id: 2052056:CTZ24_RS06705
uniprot id: A0A6I6ASB6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ClpS family.
messages: Binds to the N-terminal domain of the chaperone ClpA.
messages: Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation.

2052056:CTZ24 RS18695
gene id: 2052056:CTZ24_RS18695
uniprot id: A0A6I6B696
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
messages: Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).
messages: Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
messages: Cytoplasm

2052056:CTZ24 RS05430
gene id: 2052056:CTZ24_RS05430
uniprot id: A0A6I6AQD3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TatA/E family. TatE subfamily.
messages: Cell inner membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatE shares overlapping functions with TatA.

2052056:CTZ24 RS04780
gene id: 2052056:CTZ24_RS04780
uniprot id: A0A6I6AQQ6
names: Similarity
messages: Belongs to the UPF0234 family.

2052056:CTZ24 RS10975
gene id: 2052056:CTZ24_RS10975
uniprot id: A0A6I6AUM9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

2052056:CTZ24 RS17690
gene id: 2052056:CTZ24_RS17690
uniprot id: A0A6I6B4C0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MzrA family.
messages: Cell inner membrane
messages: Interacts with EnvZ.
messages: Modulates the activity of the EnvZ/OmpR two-component regulatory system, probably by directly modulating EnvZ enzymatic activity and increasing stability of phosphorylated OmpR.

2052056:CTZ24 RS06390
gene id: 2052056:CTZ24_RS06390
uniprot id: A0A6I6AS59
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane

2052056:CTZ24 RS14280
gene id: 2052056:CTZ24_RS14280
uniprot id: A0A6I6AZJ7
names: Subcellular Location Annotation
messages: Cytoplasm

2052056:CTZ24 RS14550
gene id: 2052056:CTZ24_RS14550
uniprot id: A0A6I6B2Z9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbE subfamily.
messages: Cell inner membrane

2052056:CTZ24 RS05025
gene id: 2052056:CTZ24_RS05025
uniprot id: A0A6I6AQ65
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

2052056:CTZ24 RS06170
gene id: 2052056:CTZ24_RS06170
uniprot id: A0A6I6AS91
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IPP isomerase type 1 family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium ion binds only when substrate is bound.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP).
messages: Cytoplasm
messages: Homodimer.

2052056:CTZ24 RS12940
gene id: 2052056:CTZ24_RS12940
uniprot id: A0A6I6AUJ2
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2052056:CTZ24 RS09995
gene id: 2052056:CTZ24_RS09995
uniprot id: A0A6I6B186
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

2052056:CTZ24 RS03915
gene id: 2052056:CTZ24_RS03915
uniprot id: A0A6I6AXT1
names: Similarity
messages: Belongs to the skp family.

2052056:CTZ24 RS11490
gene id: 2052056:CTZ24_RS11490
uniprot id: A0A6I6ATD3
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

2052056:CTZ24 RS13395
gene id: 2052056:CTZ24_RS13395
uniprot id: A0A6I6AUR5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 5 family.
messages: Periplasm

2052056:CTZ24 RS03875
gene id: 2052056:CTZ24_RS03875
uniprot id: A0A6I6AXH3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

2052056:CTZ24 RS16150
gene id: 2052056:CTZ24_RS16150
uniprot id: A0A6I6B3N6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2052056:CTZ24 RS01115
gene id: 2052056:CTZ24_RS01115
uniprot id: A0A6I6AVJ1
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2052056:CTZ24 RS14565
gene id: 2052056:CTZ24_RS14565
uniprot id: A0A6I6AZ22
names: Similarity
messages: Belongs to the MlaA family.

2052056:CTZ24 RS14945
gene id: 2052056:CTZ24_RS14945
uniprot id: A0A6I6AWY9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ElaB/YgaM/YqjD family.
messages: Cell inner membrane
messages: Membrane

2052056:CTZ24 RS20160
gene id: 2052056:CTZ24_RS20160
uniprot id: A0A6I6AXP8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family. T3SS ATPase subfamily.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

2052056:CTZ24 RS04360
gene id: 2052056:CTZ24_RS04360
uniprot id: A0A6I6AUD2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CitD family.
messages: Covalent carrier of the coenzyme of citrate lyase.
messages: Cytoplasm
messages: Oligomer with a subunit composition of (alpha,beta,gamma)6.

2052056:CTZ24 RS16375
gene id: 2052056:CTZ24_RS16375
uniprot id: A0A6I6B012
names: Function
names: Similarity
messages: Belongs to the AMP nucleosidase family.
messages: Catalyzes the hydrolysis of the N-glycosidic bond of AMP to form adenine and ribose 5-phosphate. Involved in regulation of AMP concentrations.

2052056:CTZ24 RS02330
gene id: 2052056:CTZ24_RS02330
uniprot id: A0A6I6ANM6
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

2052056:CTZ24 RS11960
gene id: 2052056:CTZ24_RS11960
uniprot id: A0A6I6AY39
names: Subcellular Location Annotation
messages: Membrane

2052056:CTZ24 RS00595
gene id: 2052056:CTZ24_RS00595
uniprot id: A0A6I6AV83
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

2052056:CTZ24 RS03890
gene id: 2052056:CTZ24_RS03890
uniprot id: A0A6I6APF4
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2052056:CTZ24 RS02280
gene id: 2052056:CTZ24_RS02280
uniprot id: A0A6I6ANL7
names: Similarity
messages: Belongs to the radical SAM superfamily. KamA family.

2052056:CTZ24 RS01875
gene id: 2052056:CTZ24_RS01875
uniprot id: A0A6I6AQ73
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2052056:CTZ24 RS11195
gene id: 2052056:CTZ24_RS11195
uniprot id: A0A6I6B188
names: Similarity
messages: Belongs to the UPF0260 family.

2052056:CTZ24 RS13000
gene id: 2052056:CTZ24_RS13000
uniprot id: A0A6I6B2B2
names: Function
names: Similarity
messages: Belongs to the APS kinase family.
messages: Catalyzes the synthesis of activated sulfate.

2052056:CTZ24 RS05150
gene id: 2052056:CTZ24_RS05150
uniprot id: A0A6I6B2J4
names: Similarity
messages: Belongs to the ABC transporter superfamily. Drug exporter-2 (TC 3.A.1.117) family.

2052056:CTZ24 RS01180
gene id: 2052056:CTZ24_RS01180
uniprot id: A0A6I6AN19
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Nudix hydrolase family. NudC subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Divalent metal cations. Mg(2+) or Mn(2+).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: mRNA decapping enzyme that specifically removes the nicotinamide adenine dinucleotide (NAD) cap from a subset of mRNAs by hydrolyzing the diphosphate linkage to produce nicotinamide mononucleotide (NMN) and 5' monophosphate mRNA. The NAD-cap is present at the 5'-end of some mRNAs and stabilizes RNA against 5'-processing. Has preference for mRNAs with a 5'-end purine. Catalyzes the hydrolysis of a broad range of dinucleotide pyrophosphates.

2052056:CTZ24 RS05980
gene id: 2052056:CTZ24_RS05980
uniprot id: A0A6I6ARY0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. Biotin synthase family.
messages: Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
messages: Homodimer.

2052056:CTZ24 RS08800
gene id: 2052056:CTZ24_RS08800
uniprot id: A0A6I6ATF2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

2052056:CTZ24 RS04965
gene id: 2052056:CTZ24_RS04965
uniprot id: A0A6I6AUZ9
names: Similarity
messages: Belongs to the ABC transporter superfamily. Drug exporter-2 (TC 3.A.1.117) family.

2052056:CTZ24 RS18405
gene id: 2052056:CTZ24_RS18405
uniprot id: A0A6I6AYR1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

2052056:CTZ24 RS08155
gene id: 2052056:CTZ24_RS08155
uniprot id: A0A6I6AT96
names: Function
names: Similarity
messages: Belongs to the FumD family.
messages: In vitro catalyzes the addition of water to fumarate, forming malate. Cannot catalyze the reverse reaction. Cannot use the cis-isomer maleate as substrate.

2052056:CTZ24 RS13645
gene id: 2052056:CTZ24_RS13645
uniprot id: A0A6I6AUK1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

2052056:CTZ24 RS10990
gene id: 2052056:CTZ24_RS10990
uniprot id: A0A6I6AXY2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell membrane
messages: Membrane

2052056:CTZ24 RS03685
gene id: 2052056:CTZ24_RS03685
uniprot id: A0A6I6API2
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic AdoMetDC family. Type 2 subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine.
messages: Heterooctamer of four alpha and four beta chains arranged as a tetramer of alpha/beta heterodimers.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl group blocking the N-terminus of the alpha chain.

2052056:CTZ24 RS17820
gene id: 2052056:CTZ24_RS17820
uniprot id: A0A6I6AWM2
names: Similarity
messages: Belongs to the UPF0307 family.

2052056:CTZ24 RS18750
gene id: 2052056:CTZ24_RS18750
uniprot id: A0A6I6B1S6
names: Similarity
messages: Belongs to the HSP15 family.

2052056:CTZ24 RS08030
gene id: 2052056:CTZ24_RS08030
uniprot id: A0A6I6B059
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

2052056:CTZ24 RS03395
gene id: 2052056:CTZ24_RS03395
uniprot id: A0A6I6AWY8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

2052056:CTZ24 RS18070
gene id: 2052056:CTZ24_RS18070
uniprot id: A0A6I6AX01
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ArgR family.
messages: Cytoplasm
messages: Regulates arginine biosynthesis genes.

2052056:CTZ24 RS17675
gene id: 2052056:CTZ24_RS17675
uniprot id: A0A6I6B2Q3
names: Subcellular Location Annotation
messages: Membrane

2052056:CTZ24 RS00460
gene id: 2052056:CTZ24_RS00460
uniprot id: A0A6I6ANL2
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.
messages: Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems.

2052056:CTZ24 RS03345
gene id: 2052056:CTZ24_RS03345
uniprot id: A0A6I6AWX7
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

2052056:CTZ24 RS01390
gene id: 2052056:CTZ24_RS01390
uniprot id: A0A6I6AT39
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
messages: Cell inner membrane
messages: Forms a membrane-associated complex with FtsE.
messages: Membrane
messages: Part of the ABC transporter FtsEX involved in cellular division.

2052056:CTZ24 RS13185
gene id: 2052056:CTZ24_RS13185
uniprot id: A0A6I6B2E2
names: Function
names: Similarity
messages: Belongs to the class-I DAHP synthase family.
messages: Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP).

2052056:CTZ24 RS15190
gene id: 2052056:CTZ24_RS15190
uniprot id: A0A6I6AX25
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

2052056:CTZ24 RS11025
gene id: 2052056:CTZ24_RS11025
uniprot id: A0A6I6AUP0
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the RssB family.
messages: Binds to RpoS.
messages: Phosphorylated. Phosphorylation stimulates the interaction with RpoS and, therefore, the proteolysis of RpoS.
messages: Regulates the turnover of the sigma S factor (RpoS) by promoting its proteolysis in exponentially growing cells. Acts by binding and delivering RpoS to the ClpXP protease. RssB is not co-degraded with RpoS, but is released from the complex and can initiate a new cycle of RpoS recognition and degradation.

2052056:CTZ24 RS17850
gene id: 2052056:CTZ24_RS17850
uniprot id: A0A6I6AYG2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PPase family.
messages: Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
messages: Cytoplasm
messages: Homohexamer.

2052056:CTZ24 RS12270
gene id: 2052056:CTZ24_RS12270
uniprot id: A0A6I6ATU6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

2052056:CTZ24 RS18545
gene id: 2052056:CTZ24_RS18545
uniprot id: A0A6I6AWZ8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family. KefB subfamily.
messages: Cell inner membrane
messages: Interacts with the regulatory subunit KefG.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Pore-forming subunit of a potassium efflux system that confers protection against electrophiles. Catalyzes K(+)/H(+) antiport.

2052056:CTZ24 RS02635
gene id: 2052056:CTZ24_RS02635
uniprot id: A0A6I6AQ49
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

2052056:CTZ24 RS01975
gene id: 2052056:CTZ24_RS01975
uniprot id: A0A6I6ANN5
names: Similarity
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.

2052056:CTZ24 RS03760
gene id: 2052056:CTZ24_RS03760
uniprot id: A0A6I6AX64
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DksA family.
messages: Cytoplasm
messages: Interacts directly with the RNA polymerase.
messages: Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters. Also required for regulation of fis expression.

2052056:CTZ24 RS14595
gene id: 2052056:CTZ24_RS14595
uniprot id: A0A6I6AVB9
names: Similarity
messages: Belongs to the UPF0115 family.

2052056:CTZ24 RS07910
gene id: 2052056:CTZ24_RS07910
uniprot id: A0A6I6AS65
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

2052056:CTZ24 RS07055
gene id: 2052056:CTZ24_RS07055
uniprot id: A0A6I6ART0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HspQ family.
messages: Cytoplasm
messages: Involved in the degradation of certain denaturated proteins, including DnaA, during heat shock stress.

2052056:CTZ24 RS18810
gene id: 2052056:CTZ24_RS18810
uniprot id: A0A6I6B1C5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NfuA family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is presumably bound at the interface of two monomers.
messages: Homodimer.
messages: Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins.

2052056:CTZ24 RS18170
gene id: 2052056:CTZ24_RS18170
uniprot id: A0A6I6AWR7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

2052056:CTZ24 RS13570
gene id: 2052056:CTZ24_RS13570
uniprot id: A0A6I6AW27
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamE family.
messages: Cell outer membrane
messages: Part of the Bam complex, which is composed of the outer membrane protein BamA, and four lipoproteins BamB, BamC, BamD and BamE.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

2052056:CTZ24 RS08420
gene id: 2052056:CTZ24_RS08420
uniprot id: A0A6I6ASE9
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

2052056:CTZ24 RS07145
gene id: 2052056:CTZ24_RS07145
uniprot id: A0A6I6AZR5
names: Function
names: Similarity
messages: Belongs to the NtaA/SnaA/DszA monooxygenase family. RutA subfamily.
messages: Catalyzes the pyrimidine ring opening between N-3 and C-4 by an unusual flavin hydroperoxide-catalyzed mechanism, adding oxygen atoms in the process to yield ureidoacrylate peracid, that immediately reacts with FMN forming ureidoacrylate and FMN-N(5)-oxide. The FMN-N(5)-oxide reacts spontaneously with NADH to produce FMN. Requires the flavin reductase RutF to regenerate FMN in vivo.

2052056:CTZ24 RS06310
gene id: 2052056:CTZ24_RS06310
uniprot id: A0A6I6AR32
names: Similarity
messages: Belongs to the arginase family. Agmatinase subfamily.

2052056:CTZ24 RS12640
gene id: 2052056:CTZ24_RS12640
uniprot id: A0A6I6AYQ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Cell inner membrane

2052056:CTZ24 RS10655
gene id: 2052056:CTZ24_RS10655
uniprot id: A0A6I6ASZ7
names: Similarity
messages: Belongs to the PspA/IM30 family.

2052056:CTZ24 RS01590
gene id: 2052056:CTZ24_RS01590
uniprot id: A0A6I6ARL6
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins.

2052056:CTZ24 RS12255
gene id: 2052056:CTZ24_RS12255
uniprot id: A0A6I6B2M4
names: Similarity
messages: Belongs to the YggT family.

2052056:CTZ24 RS06990
gene id: 2052056:CTZ24_RS06990
uniprot id: A0A6I6AR42
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ribosome modulation factor family.
messages: Cytoplasm
messages: During stationary phase, converts 70S ribosomes to an inactive dimeric form (100S ribosomes).

2052056:CTZ24 RS15510
gene id: 2052056:CTZ24_RS15510
uniprot id: A0A6I6B042
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uridine kinase family.
messages: Cytoplasm

2052056:CTZ24 RS00980
gene id: 2052056:CTZ24_RS00980
uniprot id: A0A6I6B755
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiJ family.
messages: Cytoplasm
messages: Required for ubiquinone (coenzyme Q) biosynthesis. Binds hydrophobic ubiquinone biosynthetic intermediates via its SCP2 domain and is essential for the stability of the Ubi complex. May constitute a docking platform where Ubi enzymes assemble and access their SCP2-bound polyprenyl substrates.

2052056:CTZ24 RS17900
gene id: 2052056:CTZ24_RS17900
uniprot id: A0A6I6AWX1
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

2052056:CTZ24 RS01215
gene id: 2052056:CTZ24_RS01215
uniprot id: A0A6I6AVL1
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

2052056:CTZ24 RS04220
gene id: 2052056:CTZ24_RS04220
uniprot id: A0A6I6AUA3
names: Similarity
messages: Belongs to the YkuD family.

2052056:CTZ24 RS10130
gene id: 2052056:CTZ24_RS10130
uniprot id: A0A6I6ASR4
names: Function
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
messages: Catalyzes the oxidative phosphorylation of glyceraldehyde 3-phosphate (G3P) to 1,3-bisphosphoglycerate (BPG) using the cofactor NAD. The first reaction step involves the formation of a hemiacetal intermediate between G3P and a cysteine residue, and this hemiacetal intermediate is then oxidized to a thioester, with concomitant reduction of NAD to NADH. The reduced NADH is then exchanged with the second NAD, and the thioester is attacked by a nucleophilic inorganic phosphate to produce BPG.

2052056:CTZ24 RS05505
gene id: 2052056:CTZ24_RS05505
uniprot id: A0A6I6ARQ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. Drug exporter-2 (TC 3.A.1.117) family.
messages: Cell inner membrane
messages: Membrane

2052056:CTZ24 RS06660
gene id: 2052056:CTZ24_RS06660
uniprot id: A0A6I6AUP6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 3 family.
messages: Periplasm

2052056:CTZ24 RS19970
gene id: 2052056:CTZ24_RS19970
uniprot id: A0A6I6B703
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Member of the two-component regulatory system NtrB/NtrC, which controls expression of the nitrogen-regulated (ntr) genes in response to nitrogen limitation. Phosphorylated NtrC binds directly to DNA and stimulates the formation of open promoter-sigma54-RNA polymerase complexes.

2052056:CTZ24 RS04455
gene id: 2052056:CTZ24_RS04455
uniprot id: A0A6I6APW9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lactate permease family.
messages: Cell inner membrane
messages: Membrane
messages: Uptake of L-lactate across the membrane. Can also transport D-lactate and glycolate.

2052056:CTZ24 RS04820
gene id: 2052056:CTZ24_RS04820
uniprot id: A0A6I6AQ31
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Membrane
messages: The cytochrome bo(3) ubiquinol oxidase complex is a heterooctamer of two A chains, two B chains, two C chains and two D chains.

2052056:CTZ24 RS04605
gene id: 2052056:CTZ24_RS04605
uniprot id: A0A6I6APZ7
names: Subcellular Location Annotation
messages: Membrane

2052056:CTZ24 RS00090
gene id: 2052056:CTZ24_RS00090
uniprot id: A0A6I6AV84
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

2052056:CTZ24 RS17050
gene id: 2052056:CTZ24_RS17050
uniprot id: A0A6I6B424
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. Cx-SAM synthase family.
messages: Catalyzes the conversion of S-adenosyl-L-methionine (SAM) to carboxy-S-adenosyl-L-methionine (Cx-SAM).
messages: Homodimer.

2052056:CTZ24 RS18920
gene id: 2052056:CTZ24_RS18920
uniprot id: A0A6I6B1V1
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. YhhS family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

2052056:CTZ24 RS06620
gene id: 2052056:CTZ24_RS06620
uniprot id: A0A6I6AQX8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ABC transporter superfamily. Drug exporter-2 (TC 3.A.1.117) family.
messages: Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family.
messages: Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system.
messages: The complex is composed of two ATP-binding proteins (PotA), two transmembrane proteins (PotB and PotC) and a solute-binding protein (PotD).

2052056:CTZ24 RS18670
gene id: 2052056:CTZ24_RS18670
uniprot id: A0A6I6B1N5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm
messages: Homodimer.

2052056:CTZ24 RS12385
gene id: 2052056:CTZ24_RS12385
uniprot id: A0A6I6ATW4
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

2052056:CTZ24 RS19410
gene id: 2052056:CTZ24_RS19410
uniprot id: A0A6I6B1Z7
names: Subcellular Location Annotation
messages: Membrane

2052056:CTZ24 RS12740
gene id: 2052056:CTZ24_RS12740
uniprot id: A0A6I6B2Y6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell membrane

2052056:CTZ24 RS07835
gene id: 2052056:CTZ24_RS07835
uniprot id: A0A6I6AWF2
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.

2052056:CTZ24 RS25800
gene id: 2052056:CTZ24_RS25800
uniprot id: A0A6I6B1L5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. Drug exporter-2 (TC 3.A.1.117) family.
messages: Cell inner membrane
messages: Membrane

2052056:CTZ24 RS09840
gene id: 2052056:CTZ24_RS09840
uniprot id: A0A6I6AXC1
names: Subcellular Location Annotation
messages: Membrane

2052056:CTZ24 RS15325
gene id: 2052056:CTZ24_RS15325
uniprot id: A0A6I6AVC4
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

2052056:CTZ24 RS04200
gene id: 2052056:CTZ24_RS04200
uniprot id: A0A6I6AUJ5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the methylthioribose kinase family.
messages: Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate.
messages: Homodimer.

2052056:CTZ24 RS02300
gene id: 2052056:CTZ24_RS02300
uniprot id: A0A6I6APK4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. EpmA subfamily.
messages: Homodimer.
messages: With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta-lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P.

2052056:CTZ24 RS01565
gene id: 2052056:CTZ24_RS01565
uniprot id: A0A6I6AP61
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.

2052056:CTZ24 RS06280
gene id: 2052056:CTZ24_RS06280
uniprot id: A0A6I6ARD8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. Drug exporter-2 (TC 3.A.1.117) family.
messages: Cell inner membrane
messages: Membrane

2052056:CTZ24 RS10535
gene id: 2052056:CTZ24_RS10535
uniprot id: A0A6I6AWT4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Also exhibits azoreductase activity. Catalyzes the reductive cleavage of the azo bond in aromatic azo compounds to the corresponding amines.
messages: Belongs to the azoreductase type 1 family.
messages: Binds 1 FMN per subunit.
messages: Homodimer.
messages: Quinone reductase that provides resistance to thiol-specific stress caused by electrophilic quinones.

2052056:CTZ24 RS18175
gene id: 2052056:CTZ24_RS18175
uniprot id: A0A6I6B1G5
names: Function
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

2052056:CTZ24 RS17170
gene id: 2052056:CTZ24_RS17170
uniprot id: A0A6I6AW96
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Homodimer.
messages: Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate.

2052056:CTZ24 RS04725
gene id: 2052056:CTZ24_RS04725
uniprot id: A0A6I6ARK5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.
messages: Forms an icosahedral capsid composed of 60 subunits, arranged as a dodecamer of pentamers.

2052056:CTZ24 RS06195
gene id: 2052056:CTZ24_RS06195
uniprot id: A0A6I6AVM9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

2052056:CTZ24 RS13690
gene id: 2052056:CTZ24_RS13690
uniprot id: A0A6I6AYL9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2).
messages: Homodimer.

2052056:CTZ24 RS16185
gene id: 2052056:CTZ24_RS16185
uniprot id: A0A6I6AXL6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

2052056:CTZ24 RS08410
gene id: 2052056:CTZ24_RS08410
uniprot id: A0A6I6AWH1
names: Subcellular Location Annotation
messages: Cytoplasm

2052056:CTZ24 RS15360
gene id: 2052056:CTZ24_RS15360
uniprot id: A0A6I6B4A7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.

2052056:CTZ24 RS15345
gene id: 2052056:CTZ24_RS15345
uniprot id: A0A6I6AVN8
names: Subcellular Location Annotation
messages: Membrane

2052056:CTZ24 RS10040
gene id: 2052056:CTZ24_RS10040
uniprot id: A0A6I6AU32
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. Drug exporter-2 (TC 3.A.1.117) family.
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane

2052056:CTZ24 RS00905
gene id: 2052056:CTZ24_RS00905
uniprot id: A0A6I6APQ0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phospholipase A1 family.
messages: Binds 1 Ca(2+) ion per monomer. In the dimeric form the Ca(2+) is bound by different amino acids with binding of each Ca(2+) shared with ligands coming from each monomer. The Ca(2+) ion may have a role in catalysis.
messages: Cell outer membrane
messages: Homodimer; dimerization is reversible, and the dimeric form is the active one.
messages: Hydrolysis of phosphatidylcholine with phospholipase A2 (EC 3.1.1.4) and phospholipase A1 (EC 3.1.1.32) activities.
messages: Membrane

2052056:CTZ24 RS19775
gene id: 2052056:CTZ24_RS19775
uniprot id: A0A6I6AXM0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase group 1 family.
messages: Cell membrane
messages: Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP-Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A.

2052056:CTZ24 RS06435
gene id: 2052056:CTZ24_RS06435
uniprot id: A0A6I6ARG6
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

2052056:CTZ24 RS05530
gene id: 2052056:CTZ24_RS05530
uniprot id: A0A6I6AU21
names: Similarity
messages: Belongs to the UPF0053 family.

2052056:CTZ24 RS11500
gene id: 2052056:CTZ24_RS11500
uniprot id: A0A6I6AY45
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

2052056:CTZ24 RS05740
gene id: 2052056:CTZ24_RS05740
uniprot id: A0A6I6AS18
names: Cofactor
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Binds 1 [3Fe-4S] cluster.
messages: Binds 1 [4Fe-4S] cluster.

2052056:CTZ24 RS00520
gene id: 2052056:CTZ24_RS00520
uniprot id: A0A6I6ANM3
names: Similarity
messages: Belongs to the ABC transporter superfamily. Drug exporter-2 (TC 3.A.1.117) family.

2052056:CTZ24 RS14140
gene id: 2052056:CTZ24_RS14140
uniprot id: A0A6I6AV48
names: Subcellular Location Annotation
messages: Membrane

2052056:CTZ24 RS04880
gene id: 2052056:CTZ24_RS04880
uniprot id: A0A6I6ARN2
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

2052056:CTZ24 RS20115
gene id: 2052056:CTZ24_RS20115
uniprot id: A0A6I6B2A2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

2052056:CTZ24 RS03520
gene id: 2052056:CTZ24_RS03520
uniprot id: A0A6I6AP90
names: Similarity
messages: Belongs to the Nudix hydrolase family.

2052056:CTZ24 RS13260
gene id: 2052056:CTZ24_RS13260
uniprot id: A0A6I6AZ09
names: Similarity
messages: Belongs to the thioredoxin family.

2052056:CTZ24 RS00395
gene id: 2052056:CTZ24_RS00395
uniprot id: A0A6I6AS92
names: Similarity
messages: Belongs to the RutC family.

2052056:CTZ24 RS05765
gene id: 2052056:CTZ24_RS05765
uniprot id: A0A6I6AVG4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Cell inner membrane
messages: Membrane

2052056:CTZ24 RS05760
gene id: 2052056:CTZ24_RS05760
uniprot id: A0A6I6AYP6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

2052056:CTZ24 RS18100
gene id: 2052056:CTZ24_RS18100
uniprot id: A0A6I6B0Y2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
messages: Cell membrane
messages: Forms an efflux pump with AaeB.

2052056:CTZ24 RS13560
gene id: 2052056:CTZ24_RS13560
uniprot id: A0A6I6AW87
names: Similarity
messages: Belongs to the ribosome association toxin RatA family.

2052056:CTZ24 RS18045
gene id: 2052056:CTZ24_RS18045
uniprot id: A0A6I6B0W9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-to-5' exoribonuclease specific for small oligoribonucleotides.
messages: Belongs to the oligoribonuclease family.
messages: Cytoplasm

2052056:CTZ24 RS04685
gene id: 2052056:CTZ24_RS04685
uniprot id: A0A6I6ARC2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

2052056:CTZ24 RS09150
gene id: 2052056:CTZ24_RS09150
uniprot id: A0A6I6AW15
names: Similarity
messages: Belongs to the CTP synthase family.

2052056:CTZ24 RS15155
gene id: 2052056:CTZ24_RS15155
uniprot id: A0A6I6B475
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YejK family.
messages: nucleoid

2052056:CTZ24 RS00430
gene id: 2052056:CTZ24_RS00430
uniprot id: A0A6I6AXV8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the formate dehydrogenase gamma subunit family.
messages: Membrane

2052056:CTZ24 RS18105
gene id: 2052056:CTZ24_RS18105
uniprot id: A0A6I6AWS3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AaeX family.
messages: Cell membrane

2052056:CTZ24 RS13080
gene id: 2052056:CTZ24_RS13080
uniprot id: A0A6I6AU69
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

2052056:CTZ24 RS11660
gene id: 2052056:CTZ24_RS11660
uniprot id: A0A6I6AV12
names: Domain
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.
messages: The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate.

2052056:CTZ24 RS01415
gene id: 2052056:CTZ24_RS01415
uniprot id: A0A6I6APY8
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

2052056:CTZ24 RS01130
gene id: 2052056:CTZ24_RS01130
uniprot id: A0A6I6AN10
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

2052056:CTZ24 RS10785
gene id: 2052056:CTZ24_RS10785
uniprot id: A0A6I6AXU2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase II family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.
messages: Homodimer.

2052056:CTZ24 RS13870
gene id: 2052056:CTZ24_RS13870
uniprot id: A0A6I6AW75
names: Similarity
messages: Belongs to the YfgM family.

2052056:CTZ24 RS19465
gene id: 2052056:CTZ24_RS19465
uniprot id: A0A6I6AZ87
names: Function
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.
messages: Negatively regulates the transcription of the flagellar master operon flhDC by binding to the upstream region of the operon.

2052056:CTZ24 RS03240
gene id: 2052056:CTZ24_RS03240
uniprot id: A0A6I6AWV4
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

2052056:CTZ24 RS06105
gene id: 2052056:CTZ24_RS06105
uniprot id: A0A6I6AQV4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YkuD family.
messages: Periplasm

2052056:CTZ24 RS04895
gene id: 2052056:CTZ24_RS04895
uniprot id: A0A6I6AXU1
names: Function
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. Cof family.
messages: Catalyzes the hydrolysis of 4-amino-2-methyl-5-hydroxymethylpyrimidine pyrophosphate (HMP-PP) to 4-amino-2-methyl-5-hydroxymethylpyrimidine phosphate (HMP-P).

2052056:CTZ24 RS13035
gene id: 2052056:CTZ24_RS13035
uniprot id: A0A6I6AYY8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.
messages: Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins.
messages: Cytoplasm

2052056:CTZ24 RS06080
gene id: 2052056:CTZ24_RS06080
uniprot id: A0A6I6AS01
names: Function
names: Similarity
messages: Belongs to the Dus family. DusC subfamily.
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U16 in tRNAs.

2052056:CTZ24 RS11255
gene id: 2052056:CTZ24_RS11255
uniprot id: A0A6I6B197
names: Similarity
messages: Belongs to the UPF0181 family.

2052056:CTZ24 RS23335
gene id: 2052056:CTZ24_RS23335
uniprot id: A0A6I6B1Y9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the hok/gef family.
messages: Cell inner membrane

2052056:CTZ24 RS19430
gene id: 2052056:CTZ24_RS19430
uniprot id: A0A6I6B552
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2052056:CTZ24 RS04715
gene id: 2052056:CTZ24_RS04715
uniprot id: A0A6I6AQ12
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

2052056:CTZ24 RS17640
gene id: 2052056:CTZ24_RS17640
uniprot id: A0A6I6AY25
names: Subcellular Location Annotation
messages: Membrane

2052056:CTZ24 RS12440
gene id: 2052056:CTZ24_RS12440
uniprot id: A0A6I6ATV2
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

2052056:CTZ24 RS03810
gene id: 2052056:CTZ24_RS03810
uniprot id: A0A6I6AX73
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HesB/IscA family.
messages: Binds 1 iron-sulfur cluster per subunit.
messages: Homodimer.
messages: Required for insertion of 4Fe-4S clusters for at least IspG.

2052056:CTZ24 RS06010
gene id: 2052056:CTZ24_RS06010
uniprot id: A0A6I6AQM5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

2052056:CTZ24 RS15335
gene id: 2052056:CTZ24_RS15335
uniprot id: A0A6I6B029
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.
messages: Homotetramer.

2052056:CTZ24 RS03625
gene id: 2052056:CTZ24_RS03625
uniprot id: A0A6I6APA8
names: Similarity
messages: Belongs to the UPF0231 family.

2052056:CTZ24 RS05895
gene id: 2052056:CTZ24_RS05895
uniprot id: A0A6I6B5M8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. Drug exporter-2 (TC 3.A.1.117) family.
messages: Cell inner membrane
messages: Membrane

2052056:CTZ24 RS19835
gene id: 2052056:CTZ24_RS19835
uniprot id: A0A6I6B015
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family.
messages: Membrane

2052056:CTZ24 RS13845
gene id: 2052056:CTZ24_RS13845
uniprot id: A0A6I6AUN9
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity.

2052056:CTZ24 RS03330
gene id: 2052056:CTZ24_RS03330
uniprot id: A0A6I6AQ29
names: Domain
names: Function
names: Subcellular Location Annotation
messages: Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation.
messages: Periplasm
messages: The PPIase activity resides only in the second parvulin domain. The N-terminal region and the C-terminal tail are necessary and sufficient for the chaperone activity of SurA. The PPIase activity is dispensable for SurA to function as a chaperone. The N-terminal region and the C-terminal tail are also required for porin recognition.

2052056:CTZ24 RS03405
gene id: 2052056:CTZ24_RS03405
uniprot id: A0A6I6AU54
names: Function
names: Similarity
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Homodimer.

2052056:CTZ24 RS05080
gene id: 2052056:CTZ24_RS05080
uniprot id: A0A6I6AQ74
names: Similarity
messages: Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family.

2052056:CTZ24 RS12095
gene id: 2052056:CTZ24_RS12095
uniprot id: A0A6I6AYH0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2052056:CTZ24 RS07060
gene id: 2052056:CTZ24_RS07060
uniprot id: A0A6I6ASI8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RlmI family.
messages: Cytoplasm
messages: Specifically methylates the cytosine at position 1962 (m5C1962) of 23S rRNA.

2052056:CTZ24 RS06035
gene id: 2052056:CTZ24_RS06035
uniprot id: A0A6I6AYH4
names: Similarity
messages: Belongs to the MoaD family.

2052056:CTZ24 RS10910
gene id: 2052056:CTZ24_RS10910
uniprot id: A0A6I6ATJ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0259 family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

2052056:CTZ24 RS14835
gene id: 2052056:CTZ24_RS14835
uniprot id: A0A6I6AZS9
names: Similarity
messages: Belongs to the UPF0304 family.

2052056:CTZ24 RS03720
gene id: 2052056:CTZ24_RS03720
uniprot id: A0A6I6AUB3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell inner membrane
messages: Membrane

2052056:CTZ24 RS12250
gene id: 2052056:CTZ24_RS12250
uniprot id: A0A6I6B1W7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

2052056:CTZ24 RS03900
gene id: 2052056:CTZ24_RS03900
uniprot id: A0A6I6AU49
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

2052056:CTZ24 RS08475
gene id: 2052056:CTZ24_RS08475
uniprot id: A0A6I6ASF7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyltransferase 20 family.
messages: Homotetramer.
messages: Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-alpha-D-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor.

2052056:CTZ24 RS13725
gene id: 2052056:CTZ24_RS13725
uniprot id: A0A6I6B2M9
names: Similarity
messages: Belongs to the P(II) protein family.

2052056:CTZ24 RS05070
gene id: 2052056:CTZ24_RS05070
uniprot id: A0A6I6AV17
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferrochelatase family.
messages: Catalyzes the ferrous insertion into protoporphyrin IX.
messages: Cytoplasm

2052056:CTZ24 RS11095
gene id: 2052056:CTZ24_RS11095
uniprot id: A0A6I6B1X3
names: Similarity
messages: Belongs to the asparaginase 1 family.

2052056:CTZ24 RS16315
gene id: 2052056:CTZ24_RS16315
uniprot id: A0A6I6B0H1
names: Similarity
messages: Belongs to the phosphate/phosphite/phosphonate binding protein family.

2052056:CTZ24 RS08495
gene id: 2052056:CTZ24_RS08495
uniprot id: A0A6I6AWR1
names: Similarity
messages: Belongs to the MotB family.

2052056:CTZ24 RS06860
gene id: 2052056:CTZ24_RS06860
uniprot id: A0A6I6AYZ4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MukF family.
messages: Interacts, and probably forms a ternary complex, with MukE and MukB via its C-terminal region. The complex formation is stimulated by calcium or magnesium. It is required for an interaction between MukE and MukB.
messages: Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity.
messages: nucleoid

2052056:CTZ24 RS10160
gene id: 2052056:CTZ24_RS10160
uniprot id: A0A6I6B1D7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. Drug exporter-2 (TC 3.A.1.117) family.
messages: Cell inner membrane
messages: Membrane

2052056:CTZ24 RS16140
gene id: 2052056:CTZ24_RS16140
uniprot id: A0A6I6AW18
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. Drug exporter-2 (TC 3.A.1.117) family.
messages: Cell inner membrane
messages: Part of an ABC transporter complex involved in carbohydrate import. Could be involved in ribose, galactose and/or methyl galactoside import. Responsible for energy coupling to the transport system.

2052056:CTZ24 RS18350
gene id: 2052056:CTZ24_RS18350
uniprot id: A0A6I6B1I7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

2052056:CTZ24 RS24630
gene id: 2052056:CTZ24_RS24630
uniprot id: A0A6I6B0T7
names: Subcellular Location Annotation
messages: Membrane

2052056:CTZ24 RS13165
gene id: 2052056:CTZ24_RS13165
uniprot id: A0A6I6AW19
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein uS19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein uS19.

2052056:CTZ24 RS07140
gene id: 2052056:CTZ24_RS07140
uniprot id: A0A6I6AUZ7
names: Function
names: Similarity
messages: Belongs to the isochorismatase family. RutB subfamily.
messages: Hydrolyzes ureidoacrylate to form aminoacrylate and carbamate. The carbamate hydrolyzes spontaneously, thereby releasing one of the nitrogen atoms of the pyrimidine ring as ammonia and one of its carbon atoms as CO2.

2052056:CTZ24 RS07800
gene id: 2052056:CTZ24_RS07800
uniprot id: A0A6I6ARN8
names: Function
names: Similarity
messages: Belongs to the FlgN family.
messages: Required for the efficient initiation of filament assembly.

2052056:CTZ24 RS07945
gene id: 2052056:CTZ24_RS07945
uniprot id: A0A6I6ARU3
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. TatD-type hydrolase family.

2052056:CTZ24 RS08605
gene id: 2052056:CTZ24_RS08605
uniprot id: A0A6I6AS42
names: Function
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family. AstD subfamily.
messages: Catalyzes the NAD-dependent reduction of succinylglutamate semialdehyde into succinylglutamate.

2052056:CTZ24 RS00100
gene id: 2052056:CTZ24_RS00100
uniprot id: A0A6I6ASC1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

2052056:CTZ24 RS10805
gene id: 2052056:CTZ24_RS10805
uniprot id: A0A6I6AUL1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

2052056:CTZ24 RS05915
gene id: 2052056:CTZ24_RS05915
uniprot id: A0A6I6AS45
names: Function
names: Similarity
names: Subunit
messages: Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: Homodimer.

2052056:CTZ24 RS12535
gene id: 2052056:CTZ24_RS12535
uniprot id: A0A6I6AXX2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbC subfamily.
messages: Periplasm
messages: Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process.

2052056:CTZ24 RS02685
gene id: 2052056:CTZ24_RS02685
uniprot id: A0A6I6APS5
names: Function
names: Similarity
messages: Belongs to the UbiT family.
messages: Required for O(2)-independent ubiquinone (coenzyme Q) biosynthesis. Likely functions as an accessory factor.

2052056:CTZ24 RS20015
gene id: 2052056:CTZ24_RS20015
uniprot id: A0A6I6AZI0
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MobA family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: The N-terminal domain determines nucleotide recognition and specific binding, while the C-terminal domain determines the specific binding to the target protein.
messages: Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor.

2052056:CTZ24 RS10495
gene id: 2052056:CTZ24_RS10495
uniprot id: A0A6I6ASX4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Basic amino acid/polyamine antiporter (APA) (TC 2.A.3.2) family.
messages: Membrane

2052056:CTZ24 RS01705
gene id: 2052056:CTZ24_RS01705
uniprot id: A0A6I6ANB9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

2052056:CTZ24 RS05010
gene id: 2052056:CTZ24_RS05010
uniprot id: A0A6I6AYA5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

2052056:CTZ24 RS15435
gene id: 2052056:CTZ24_RS15435
uniprot id: A0A6I6AVQ4
names: Subcellular Location Annotation
messages: Membrane

2052056:CTZ24 RS11710
gene id: 2052056:CTZ24_RS11710
uniprot id: A0A6I6AV21
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ExbD/TolR family.
messages: Cell inner membrane
messages: Cell membrane
messages: Involved in the TonB-dependent energy-dependent transport of various receptor-bound substrates.
messages: Membrane
messages: The accessory proteins ExbB and ExbD seem to form a complex with TonB.

2052056:CTZ24 RS06715
gene id: 2052056:CTZ24_RS06715
uniprot id: A0A6I6AZC2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

2052056:CTZ24 RS13010
gene id: 2052056:CTZ24_RS13010
uniprot id: A0A6I6AYW9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsB family.
messages: Cell inner membrane
messages: Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.
messages: Part of a complex composed of FtsB, FtsL and FtsQ.

2052056:CTZ24 RS18215
gene id: 2052056:CTZ24_RS18215
uniprot id: A0A6I6B102
names: Function
names: Similarity
messages: Belongs to the Dus family. DusB subfamily.
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

2052056:CTZ24 RS05420
gene id: 2052056:CTZ24_RS05420
uniprot id: A0A6I6ATZ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

2052056:CTZ24 RS02580
gene id: 2052056:CTZ24_RS02580
uniprot id: A0A6I6AWK8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2052056:CTZ24 RS13960
gene id: 2052056:CTZ24_RS13960
uniprot id: A0A6I6AV13
names: Similarity
messages: Belongs to the GppA/Ppx family.

2052056:CTZ24 RS03230
gene id: 2052056:CTZ24_RS03230
uniprot id: A0A6I6AQ13
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetate uptake transporter (AceTr) (TC 2.A.96) family.
messages: Membrane

2052056:CTZ24 RS17740
gene id: 2052056:CTZ24_RS17740
uniprot id: A0A6I6AWU7
names: Similarity
messages: Belongs to the UPF0102 family.

2052056:CTZ24 RS10435
gene id: 2052056:CTZ24_RS10435
uniprot id: A0A6I6ASX3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Cell inner membrane
messages: Membrane

2052056:CTZ24 RS01350
gene id: 2052056:CTZ24_RS01350
uniprot id: A0A6I6AN47
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sulfur carrier protein TusA family.
messages: Cytoplasm
messages: Interacts with IscS.
messages: Sulfur carrier protein involved in sulfur trafficking in the cell. Part of a sulfur-relay system required for 2-thiolation during synthesis of 2-thiouridine of the modified wobble base 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) in tRNA. Interacts with IscS and stimulates its cysteine desulfurase activity. Accepts an activated sulfur from IscS, which is then transferred to TusD, and thus determines the direction of sulfur flow from IscS to 2-thiouridine formation. Also appears to be involved in sulfur transfer for the biosynthesis of molybdopterin.

2052056:CTZ24 RS03270
gene id: 2052056:CTZ24_RS03270
uniprot id: A0A6I6ATT0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell membrane
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

2052056:CTZ24 RS13370
gene id: 2052056:CTZ24_RS13370
uniprot id: A0A6I6AYF6
names: Similarity
messages: Belongs to the ABC transporter superfamily. Drug exporter-2 (TC 3.A.1.117) family.

2052056:CTZ24 RS02390
gene id: 2052056:CTZ24_RS02390
uniprot id: A0A6I6AQH0
names: Function
names: Similarity
messages: Belongs to the ABC transporter superfamily. Drug exporter-2 (TC 3.A.1.117) family.
messages: Belongs to the ABC transporter superfamily. Outer membrane lipopolysaccharide export (TC 1.B.42) family.
messages: Part of the ABC transporter complex LptBFG involved in the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane. Probably responsible for energy coupling to the transport system.

2052056:CTZ24 RS16900
gene id: 2052056:CTZ24_RS16900
uniprot id: A0A6I6B0B4
names: Subcellular Location Annotation
messages: Membrane

2052056:CTZ24 RS06565
gene id: 2052056:CTZ24_RS06565
uniprot id: A0A6I6AR77
names: Function
names: Similarity
messages: Belongs to the peptidase S11 family.
messages: Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors.

2052056:CTZ24 RS04700
gene id: 2052056:CTZ24_RS04700
uniprot id: A0A6I6AUV0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Cell membrane
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

2052056:CTZ24 RS17005
gene id: 2052056:CTZ24_RS17005
uniprot id: A0A6I6B587
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

2052056:CTZ24 RS25260
gene id: 2052056:CTZ24_RS25260
uniprot id: A0A6I6B5R1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

2052056:CTZ24 RS16590
gene id: 2052056:CTZ24_RS16590
uniprot id: A0A6I6AY18
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliP/MopC/SpaP family.
messages: Cell membrane
messages: Membrane
messages: Plays a role in the flagellum-specific transport system.

2052056:CTZ24 RS24635
gene id: 2052056:CTZ24_RS24635
uniprot id: A0A6I6B0R0
names: Similarity
messages: Belongs to the class-I fumarase family.

2052056:CTZ24 RS26450
gene id: 2052056:CTZ24_RS26450
uniprot id: A0A6I6B1W6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2052056:CTZ24 RS02460
gene id: 2052056:CTZ24_RS02460
uniprot id: A0A6I6AWJ0
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

2052056:CTZ24 RS03095
gene id: 2052056:CTZ24_RS03095
uniprot id: A0A6I6AP07
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.
messages: Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.
messages: Belongs to the ABC transporter superfamily. Drug exporter-2 (TC 3.A.1.117) family.
messages: Cytoplasm
messages: Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).
messages: The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.
messages: The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1.

2052056:CTZ24 RS18360
gene id: 2052056:CTZ24_RS18360
uniprot id: A0A6I6AX55
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

2052056:CTZ24 RS01325
gene id: 2052056:CTZ24_RS01325
uniprot id: A0A6I6APE9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
messages: Homotetramer.
messages: Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc.

2052056:CTZ24 RS16600
gene id: 2052056:CTZ24_RS16600
uniprot id: A0A6I6AVZ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliN/MopA/SpaO family.
messages: Cell membrane
messages: FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
messages: Membrane

2052056:CTZ24 RS02965
gene id: 2052056:CTZ24_RS02965
uniprot id: A0A6I6ATX7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2052056:CTZ24 RS20060
gene id: 2052056:CTZ24_RS20060
uniprot id: A0A6I6B5Z3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbsD / FucU family. RbsD subfamily.
messages: Catalyzes the interconversion of beta-pyran and beta-furan forms of D-ribose.
messages: Cytoplasm
messages: Homodecamer.

2052056:CTZ24 RS10110
gene id: 2052056:CTZ24_RS10110
uniprot id: A0A6I6B7B9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DoxX family.
messages: Membrane

2052056:CTZ24 RS10280
gene id: 2052056:CTZ24_RS10280
uniprot id: A0A6I6AST8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

2052056:CTZ24 RS19880
gene id: 2052056:CTZ24_RS19880
uniprot id: A0A6I6AXP2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0126 family.
messages: Membrane

2052056:CTZ24 RS03320
gene id: 2052056:CTZ24_RS03320
uniprot id: A0A6I6ATU4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

2052056:CTZ24 RS10145
gene id: 2052056:CTZ24_RS10145
uniprot id: A0A6I6AT71
names: Similarity
messages: Belongs to the arginase family.

2052056:CTZ24 RS08730
gene id: 2052056:CTZ24_RS08730
uniprot id: A0A6I6ATI9
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

2052056:CTZ24 RS13815
gene id: 2052056:CTZ24_RS13815
uniprot id: A0A6I6AUY6
names: Cofactor
names: Function
messages: Binds 1 [2Fe-2S] cluster.
messages: Regulates the transcription of several operons and genes involved in the biogenesis of Fe-S clusters and Fe-S-containing proteins.

2052056:CTZ24 RS12290
gene id: 2052056:CTZ24_RS12290
uniprot id: A0A6I6AU80
names: Similarity
messages: Belongs to the EndA/NucM nuclease family.

2052056:CTZ24 RS17685
gene id: 2052056:CTZ24_RS17685
uniprot id: A0A6I6AYD6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Membrane

2052056:CTZ24 RS16620
gene id: 2052056:CTZ24_RS16620
uniprot id: A0A6I6AWA0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliJ family.
messages: Cell membrane
messages: Flagellar protein that affects chemotactic events.
messages: Membrane

2052056:CTZ24 RS24640
gene id: 2052056:CTZ24_RS24640
uniprot id: A0A6I6B5T4
names: Similarity
messages: Belongs to the class-I fumarase family.

2052056:CTZ24 RS18885
gene id: 2052056:CTZ24_RS18885
uniprot id: A0A6I6AX46
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

2052056:CTZ24 RS07890
gene id: 2052056:CTZ24_RS07890
uniprot id: A0A6I6ART5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

2052056:CTZ24 RS08045
gene id: 2052056:CTZ24_RS08045
uniprot id: A0A6I6ARV6
names: Caution
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 2 residues (Tyr-94 and Arg-97) present in a large hydrophobic pocket are probably involved in substrate specificity. They are important for desuccinylation activity, but dispensable for deacetylation activity.
messages: Belongs to the sirtuin family. Class III subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-dependent lysine deacetylase that specifically removes acetyl groups on target proteins. Also acts as a protein-lysine deacylase by mediating protein desuccinylation and de-2-hydroxyisobutyrylation. Modulates the activities of several proteins which are inactive in their acylated form.

2052056:CTZ24 RS10350
gene id: 2052056:CTZ24_RS10350
uniprot id: A0A6I6AUB2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the aldolase class II family. RhaD subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the reversible cleavage of L-rhamnulose-1-phosphate to dihydroxyacetone phosphate (DHAP) and L-lactaldehyde.
messages: Cytoplasm
messages: Homotetramer.

2052056:CTZ24 RS20125
gene id: 2052056:CTZ24_RS20125
uniprot id: A0A6I6AY01
names: Subcellular Location Annotation
messages: Membrane

2052056:CTZ24 RS14965
gene id: 2052056:CTZ24_RS14965
uniprot id: A0A6I6B446
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

2052056:CTZ24 RS00075
gene id: 2052056:CTZ24_RS00075
uniprot id: A0A6I6APA9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Cell membrane
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

2052056:CTZ24 RS00645
gene id: 2052056:CTZ24_RS00645
uniprot id: A0A6I6ASL0
names: Similarity
messages: Belongs to the glycosyl hydrolase 8 (cellulase D) family.

2052056:CTZ24 RS03980
gene id: 2052056:CTZ24_RS03980
uniprot id: A0A6I6AXK0
names: Similarity
messages: Belongs to the UPF0253 family.

2052056:CTZ24 RS11215
gene id: 2052056:CTZ24_RS11215
uniprot id: A0A6I6AT91
names: Function
names: Similarity
names: Subunit
messages: ATPase required for the correct placement of the division site. Cell division inhibitors MinC and MinD act in concert to form an inhibitor capable of blocking formation of the polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings.
messages: Belongs to the ParA family. MinD subfamily.
messages: Interacts with MinC and FtsZ.

2052056:CTZ24 RS02265
gene id: 2052056:CTZ24_RS02265
uniprot id: A0A6I6AWE4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

2052056:CTZ24 RS18430
gene id: 2052056:CTZ24_RS18430
uniprot id: A0A6I6B1M5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

2052056:CTZ24 RS19415
gene id: 2052056:CTZ24_RS19415
uniprot id: A0A6I6AZ80
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2052056:CTZ24 RS11575
gene id: 2052056:CTZ24_RS11575
uniprot id: A0A6I6AY87
names: Function
names: Similarity
names: Subunit
messages: Acts on ADP-mannose and ADP-glucose as well as ADP-ribose. Prevents glycogen biosynthesis. The reaction catalyzed by this enzyme is a limiting step of the gluconeogenic process.
messages: Belongs to the Nudix hydrolase family. NudF subfamily.
messages: Homodimer.

2052056:CTZ24 RS06525
gene id: 2052056:CTZ24_RS06525
uniprot id: A0A6I6AVH5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

2052056:CTZ24 RS08815
gene id: 2052056:CTZ24_RS08815
uniprot id: A0A6I6AWV7
names: Similarity
messages: Belongs to the HesB/IscA family.

2052056:CTZ24 RS24615
gene id: 2052056:CTZ24_RS24615
uniprot id: A0A6I6BB60
names: Similarity
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.

2052056:CTZ24 RS12910
gene id: 2052056:CTZ24_RS12910
uniprot id: A0A6I6AYV3
names: Function
names: Similarity
messages: Belongs to the HIBADH-related family. 2-hydroxy-3-oxopropionate reductase subfamily.
messages: Catalyzes the reduction of tatronate semialdehyde to D-glycerate.

2052056:CTZ24 RS15545
gene id: 2052056:CTZ24_RS15545
uniprot id: A0A6I6AX80
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the etk/wzc family.
messages: Cell inner membrane
messages: Membrane

2052056:CTZ24 RS06800
gene id: 2052056:CTZ24_RS06800
uniprot id: A0A6I6ARN6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

2052056:CTZ24 RS06720
gene id: 2052056:CTZ24_RS06720
uniprot id: A0A6I6AVV9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L/F-transferase family.
messages: Cytoplasm
messages: Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.

2052056:CTZ24 RS05450
gene id: 2052056:CTZ24_RS05450
uniprot id: A0A6I6ARQ0
names: Function
names: Similarity
messages: Belongs to the peptidase S11 family.
messages: Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors.

2052056:CTZ24 RS18225
gene id: 2052056:CTZ24_RS18225
uniprot id: A0A6I6AWS4
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

2052056:CTZ24 RS14950
gene id: 2052056:CTZ24_RS14950
uniprot id: A0A6I6AVH8
names: Similarity
messages: Belongs to the CinA family.

2052056:CTZ24 RS12425
gene id: 2052056:CTZ24_RS12425
uniprot id: A0A6I6AYM4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LysR transcriptional regulatory family.
messages: Controls the transcription of genes involved in arginine and lysine metabolism.
messages: Homodimer.

2052056:CTZ24 RS01200
gene id: 2052056:CTZ24_RS01200
uniprot id: A0A6I6ANY1
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

2052056:CTZ24 RS02065
gene id: 2052056:CTZ24_RS02065
uniprot id: A0A6I6ATG5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

2052056:CTZ24 RS14845
gene id: 2052056:CTZ24_RS14845
uniprot id: A0A6I6AVG3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 5DNU family.
messages: Catalyzes the strictly specific dephosphorylation of 2'-deoxyribonucleoside 5'-monophosphates.
messages: Cytoplasm
messages: Homodimer.

2052056:CTZ24 RS11570
gene id: 2052056:CTZ24_RS11570
uniprot id: A0A6I6B1F2
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

2052056:CTZ24 RS01475
gene id: 2052056:CTZ24_RS01475
uniprot id: A0A6I6AVV8
names: Similarity
messages: Belongs to the gluconokinase GntK/GntV family.

2052056:CTZ24 RS05545
gene id: 2052056:CTZ24_RS05545
uniprot id: A0A6I6AV03
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methylthiotransferase family. MiaB subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
messages: Cytoplasm
messages: Monomer.

2052056:CTZ24 RS14760
gene id: 2052056:CTZ24_RS14760
uniprot id: A0A6I6B415
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane

2052056:CTZ24 RS01410
gene id: 2052056:CTZ24_RS01410
uniprot id: A0A6I6AST4
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

2052056:CTZ24 RS17065
gene id: 2052056:CTZ24_RS17065
uniprot id: A0A6I6B0D9
names: Cofactor
messages: Binds 1 Mg(2+) ion per subunit.

2052056:CTZ24 RS05635
gene id: 2052056:CTZ24_RS05635
uniprot id: A0A6I6AV14
names: Function
names: Similarity
messages: Belongs to the flavodoxin family.
messages: Low-potential electron donor to a number of redox enzymes.

2052056:CTZ24 RS08705
gene id: 2052056:CTZ24_RS08705
uniprot id: A0A6I6AVU3
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.

2052056:CTZ24 RS20085
gene id: 2052056:CTZ24_RS20085
uniprot id: A0A6I6B730
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HAK/KUP transporter (TC 2.A.72) family.
messages: Cell membrane
messages: Membrane
messages: Responsible for the low-affinity transport of potassium into the cell. Likely operates as a K(+):H(+) symporter.

2052056:CTZ24 RS06855
gene id: 2052056:CTZ24_RS06855
uniprot id: A0A6I6ASE2
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. CmoM family.
messages: Catalyzes the methylation of 5-carboxymethoxyuridine (cmo5U) to form 5-methoxycarbonylmethoxyuridine (mcmo5U) at position 34 in tRNAs.

2052056:CTZ24 RS07070
gene id: 2052056:CTZ24_RS07070
uniprot id: A0A6I6AZL7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dsrC/tusE family.
messages: Cytoplasm
messages: Interacts with the TusBCD complex. Interacts with MnmA.
messages: Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Could accept sulfur from TusD.

2052056:CTZ24 RS05730
gene id: 2052056:CTZ24_RS05730
uniprot id: A0A6I6AQH6
names: Cofactor
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane
messages: Membrane-anchoring subunit of succinate dehydrogenase (SDH).
messages: The heme is bound between the two transmembrane subunits.

2052056:CTZ24 RS11085
gene id: 2052056:CTZ24_RS11085
uniprot id: A0A6I6AUP7
names: Cofactor
names: Similarity
messages: Belongs to the nitroreductase family.
messages: Binds 1 FMN per subunit.

2052056:CTZ24 RS16170
gene id: 2052056:CTZ24_RS16170
uniprot id: A0A6I6AVR3
names: Function
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. S-2-haloalkanoic acid dehalogenase family.
messages: Catalyzes the hydrolytic dehalogenation of small (S)-2-haloalkanoic acids to yield the corresponding (R)-2-hydroxyalkanoic acids.

2052056:CTZ24 RS01405
gene id: 2052056:CTZ24_RS01405
uniprot id: A0A6I6AN91
names: Similarity
messages: Belongs to the leucine-binding protein family.

2052056:CTZ24 RS12315
gene id: 2052056:CTZ24_RS12315
uniprot id: A0A6I6B2N5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

2052056:CTZ24 RS00840
gene id: 2052056:CTZ24_RS00840
uniprot id: A0A6I6AMZ7
names: Function
names: Similarity
messages: Belongs to the uroporphyrinogen-III synthase family.
messages: Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.

2052056:CTZ24 RS24310
gene id: 2052056:CTZ24_RS24310
uniprot id: A0A6I6B5G5
names: Similarity
messages: Belongs to the glutathione peroxidase family.

2052056:CTZ24 RS25790
gene id: 2052056:CTZ24_RS25790
uniprot id: A0A6I6B6K6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

2052056:CTZ24 RS03645
gene id: 2052056:CTZ24_RS03645
uniprot id: A0A6I6B2I4
names: Subcellular Location Annotation
messages: Membrane

2052056:CTZ24 RS10005
gene id: 2052056:CTZ24_RS10005
uniprot id: A0A6I6AXE7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

2052056:CTZ24 RS16580
gene id: 2052056:CTZ24_RS16580
uniprot id: A0A6I6B509
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliR/MopE/SpaR family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

2052056:CTZ24 RS06630
gene id: 2052056:CTZ24_RS06630
uniprot id: A0A6I6ASH7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

2052056:CTZ24 RS11600
gene id: 2052056:CTZ24_RS11600
uniprot id: A0A6I6AV23
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2052056:CTZ24 RS06485
gene id: 2052056:CTZ24_RS06485
uniprot id: A0A6I6ARH5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone-like protein H-NS family.
messages: nucleoid

2052056:CTZ24 RS02245
gene id: 2052056:CTZ24_RS02245
uniprot id: A0A6I6AQE3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CutA family.
messages: Cytoplasm
messages: Homotrimer.
messages: Involved in resistance toward heavy metals.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2052056:CTZ24 RS09435
gene id: 2052056:CTZ24_RS09435
uniprot id: A0A6I6AWZ7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PqqD family.
messages: Functions as a PqqA binding protein and presents PqqA to PqqE, in the pyrroloquinoline quinone (PQQ) biosynthetic pathway.
messages: Monomer. Interacts with PqqE.

2052056:CTZ24 RS05680
gene id: 2052056:CTZ24_RS05680
uniprot id: A0A6I6AQG9
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

2052056:CTZ24 RS08480
gene id: 2052056:CTZ24_RS08480
uniprot id: A0A6I6AT94
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FlhD family.
messages: Cytoplasm
messages: Functions in complex with FlhC as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region. Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes. Also regulates genes whose products function in a variety of physiological pathways.
messages: Homodimer; disulfide-linked. Forms a heterohexamer composed of two FlhC and four FlhD subunits. Each FlhC binds a FlhD dimer, forming a heterotrimer, and a hexamer assembles by dimerization of two heterotrimers.
messages: The C-terminal region contains a putative helix-turn-helix (HTH) motif, suggesting that this region may bind DNA.

2052056:CTZ24 RS16765
gene id: 2052056:CTZ24_RS16765
uniprot id: A0A6I6AXX4
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

2052056:CTZ24 RS00210
gene id: 2052056:CTZ24_RS00210
uniprot id: A0A6I6AQY6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. GhrB subfamily.
messages: Catalyzes the NADPH-dependent reduction of glyoxylate and hydroxypyruvate into glycolate and glycerate, respectively.
messages: Cytoplasm
messages: Homodimer.

2052056:CTZ24 RS06905
gene id: 2052056:CTZ24_RS06905
uniprot id: A0A6I6ASF4
names: Function
names: PTM
names: Similarity
messages: Belongs to the NAPRTase family.
messages: Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP.
messages: Transiently phosphorylated on a His residue during the reaction cycle. Phosphorylation strongly increases the affinity for substrates and increases the rate of nicotinate D-ribonucleotide production. Dephosphorylation regenerates the low-affinity form of the enzyme, leading to product release.

2052056:CTZ24 RS08850
gene id: 2052056:CTZ24_RS08850
uniprot id: A0A6I6ATG2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A highly abundant outer membrane lipoprotein that controls the distance between the inner and outer membranes. The only protein known to be covalently linked to the peptidoglycan network (PGN). Also non-covalently binds the PGN. The link between the cell outer membrane and PGN contributes to maintenance of the structural and functional integrity of the cell envelope, and maintains the correct distance between the PGN and the outer membrane.
messages: Belongs to the Lpp family.
messages: Cell outer membrane
messages: Homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: cell wall

2052056:CTZ24 RS08825
gene id: 2052056:CTZ24_RS08825
uniprot id: A0A6I6AS72
names: Similarity
messages: Belongs to the ABC transporter superfamily. Drug exporter-2 (TC 3.A.1.117) family.
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

2052056:CTZ24 RS18145
gene id: 2052056:CTZ24_RS18145
uniprot id: A0A6I6B1C9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

2052056:CTZ24 RS05925
gene id: 2052056:CTZ24_RS05925
uniprot id: A0A6I6ARX1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. GalK subfamily.
messages: Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2052056:CTZ24 RS18595
gene id: 2052056:CTZ24_RS18595
uniprot id: A0A6I6B670
names: Similarity
messages: Belongs to the phosphoribulokinase family.

2052056:CTZ24 RS18375
gene id: 2052056:CTZ24_RS18375
uniprot id: A0A6I6B634
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

2052056:CTZ24 RS16585
gene id: 2052056:CTZ24_RS16585
uniprot id: A0A6I6B0M2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliQ/MopD/SpaQ family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

2052056:CTZ24 RS00975
gene id: 2052056:CTZ24_RS00975
uniprot id: A0A6I6AVH4
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2).

2052056:CTZ24 RS14275
gene id: 2052056:CTZ24_RS14275
uniprot id: A0A6I6AUT6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).

2052056:CTZ24 RS02575
gene id: 2052056:CTZ24_RS02575
uniprot id: A0A6I6AWH8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.
messages: Cytoplasm
messages: Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.

2052056:CTZ24 RS10510
gene id: 2052056:CTZ24_RS10510
uniprot id: A0A6I6ATC6
names: Subcellular Location Annotation
messages: Cell inner membrane

2052056:CTZ24 RS18295
gene id: 2052056:CTZ24_RS18295
uniprot id: A0A6I6AWT3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

2052056:CTZ24 RS18615
gene id: 2052056:CTZ24_RS18615
uniprot id: A0A6I6AWZ5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in both the arginine and lysine biosynthetic pathways.

2052056:CTZ24 RS11220
gene id: 2052056:CTZ24_RS11220
uniprot id: A0A6I6AT84
names: Function
names: Similarity
messages: Belongs to the MinE family.
messages: Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.

2052056:CTZ24 RS05470
gene id: 2052056:CTZ24_RS05470
uniprot id: A0A6I6AVB0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

2052056:CTZ24 RS03415
gene id: 2052056:CTZ24_RS03415
uniprot id: A0A6I6ASR6
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

2052056:CTZ24 RS02810
gene id: 2052056:CTZ24_RS02810
uniprot id: A0A6I6ATV1
names: Cofactor
messages: Binds 3 heme c groups covalently per subunit.

2052056:CTZ24 RS23615
gene id: 2052056:CTZ24_RS23615
uniprot id: A0A6I6BAA6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. Drug exporter-2 (TC 3.A.1.117) family.
messages: Cell inner membrane
messages: Membrane

2052056:CTZ24 RS16320
gene id: 2052056:CTZ24_RS16320
uniprot id: A0A6I6B004
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

2052056:CTZ24 RS17980
gene id: 2052056:CTZ24_RS17980
uniprot id: A0A6I6B0V7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the band 7/mec-2 family. HflC subfamily.
messages: HflC and HflK could regulate a protease.
messages: Membrane

2052056:CTZ24 RS12930
gene id: 2052056:CTZ24_RS12930
uniprot id: A0A6I6AYW8
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

2052056:CTZ24 RS05755
gene id: 2052056:CTZ24_RS05755
uniprot id: A0A6I6AYA9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

2052056:CTZ24 RS06345
gene id: 2052056:CTZ24_RS06345
uniprot id: A0A6I6AYN9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the urocanase family.
messages: Binds 1 NAD(+) per subunit.
messages: Catalyzes the conversion of urocanate to 4-imidazolone-5-propionate.
messages: Cytoplasm

2052056:CTZ24 RS18535
gene id: 2052056:CTZ24_RS18535
uniprot id: A0A6I6B1P3
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

2052056:CTZ24 RS14415
gene id: 2052056:CTZ24_RS14415
uniprot id: A0A6I6AWG9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial glucokinase family.
messages: Cytoplasm

2052056:CTZ24 RS14020
gene id: 2052056:CTZ24_RS14020
uniprot id: A0A6I6B2I0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaA family. HdA subfamily.
messages: Mediates the interaction of DNA replication inititator protein DnaA with DNA polymerase subunit beta sliding clamp (dnaN). Stimulates hydrolysis of ATP-DnaA to ADP-DnaA, rendering DnaA inactive for reinititation, a process called regulatory inhibition of DnaA or RIDA.
messages: The active form seems to be an ADP-bound monomer. Forms the RIDA complex (regulatory inactivation of DnaA) of ATP-DnaA, ADP-Hda and the DNA-loaded beta sliding clamp (dnaN).

2052056:CTZ24 RS14545
gene id: 2052056:CTZ24_RS14545
uniprot id: A0A6I6AWI7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmF/CycK/Ccl1/NrfE/CcsA family.
messages: Cell inner membrane
messages: Membrane

2052056:CTZ24 RS25580
gene id: 2052056:CTZ24_RS25580
uniprot id: A0A6I6B6G9
names: Similarity
messages: Belongs to the nitroreductase family.

2052056:CTZ24 RS08050
gene id: 2052056:CTZ24_RS08050
uniprot id: A0A6I6ART6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein PotD/PotF family.
messages: Periplasm
messages: Required for the activity of the bacterial periplasmic transport system of putrescine.

2052056:CTZ24 RS26335
gene id: 2052056:CTZ24_RS26335
uniprot id: A0A6I6B6W5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2052056:CTZ24 RS19240
gene id: 2052056:CTZ24_RS19240
uniprot id: A0A6I6B1J5
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

2052056:CTZ24 RS18440
gene id: 2052056:CTZ24_RS18440
uniprot id: A0A6I6AWX9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

2052056:CTZ24 RS18165
gene id: 2052056:CTZ24_RS18165
uniprot id: A0A6I6AWT2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MsrQ family.
messages: Binds 1 FMN per subunit.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.
messages: Cell membrane
messages: Heterodimer of a catalytic subunit (MsrP) and a heme-binding subunit (MsrQ).
messages: Membrane
messages: Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain.

2052056:CTZ24 RS03255
gene id: 2052056:CTZ24_RS03255
uniprot id: A0A6I6ASN8
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

2052056:CTZ24 RS18370
gene id: 2052056:CTZ24_RS18370
uniprot id: A0A6I6B4L9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

2052056:CTZ24 RS16775
gene id: 2052056:CTZ24_RS16775
uniprot id: A0A6I6AXV7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. Drug exporter-2 (TC 3.A.1.117) family.
messages: Cell inner membrane
messages: Membrane

2052056:CTZ24 RS10580
gene id: 2052056:CTZ24_RS10580
uniprot id: A0A6I6AXQ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

2052056:CTZ24 RS04775
gene id: 2052056:CTZ24_RS04775
uniprot id: A0A6I6ARL4
names: Function
names: Similarity
messages: Belongs to the ketopantoate reductase family.
messages: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.

2052056:CTZ24 RS11830
gene id: 2052056:CTZ24_RS11830
uniprot id: A0A6I6AXH9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0391 family.
messages: Cell membrane

2052056:CTZ24 RS03865
gene id: 2052056:CTZ24_RS03865
uniprot id: A0A6I6AX82
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

2052056:CTZ24 RS03710
gene id: 2052056:CTZ24_RS03710
uniprot id: A0A6I6AX53
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm
messages: Purine salvage pathway enzyme which catalyzes the transfer of the ribosyl-5-phosphate group from 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to the N9 position of hypoxanthine to yield IMP (inosine 5'-monophosphate). To a lesser extent, can also act on guanine leading to GMP, but shows a highly less efficient activity with xanthine.

2052056:CTZ24 RS18065
gene id: 2052056:CTZ24_RS18065
uniprot id: A0A6I6AYJ8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LDH/MDH superfamily. MDH type 1 family.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.
messages: Homodimer.

2052056:CTZ24 RS18500
gene id: 2052056:CTZ24_RS18500
uniprot id: A0A6I6AWX2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

2052056:CTZ24 RS09230
gene id: 2052056:CTZ24_RS09230
uniprot id: A0A6I6ATN8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the arabinose isomerase family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the conversion of L-arabinose to L-ribulose.
messages: Homohexamer.

2052056:CTZ24 RS12280
gene id: 2052056:CTZ24_RS12280
uniprot id: A0A6I6AYK2
names: Similarity
messages: Belongs to the prokaryotic GSH synthase family.

2052056:CTZ24 RS03940
gene id: 2052056:CTZ24_RS03940
uniprot id: A0A6I6AT14
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

2052056:CTZ24 RS10770
gene id: 2052056:CTZ24_RS10770
uniprot id: A0A6I6AUJ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LapB family.
messages: Cell inner membrane
messages: Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane.

2052056:CTZ24 RS11030
gene id: 2052056:CTZ24_RS11030
uniprot id: A0A6I6B157
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2052056:CTZ24 RS25405
gene id: 2052056:CTZ24_RS25405
uniprot id: A0A6I6BBY4
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family. AlsE subfamily.
messages: Catalyzes the reversible epimerization of D-allulose 6-phosphate to D-fructose 6-phosphate. Can also catalyze with lower efficiency the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

2052056:CTZ24 RS00400
gene id: 2052056:CTZ24_RS00400
uniprot id: A0A6I6APG2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

2052056:CTZ24 RS18700
gene id: 2052056:CTZ24_RS18700
uniprot id: A0A6I6B1R7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Monomer.

2052056:CTZ24 RS00910
gene id: 2052056:CTZ24_RS00910
uniprot id: A0A6I6ANT6
names: Similarity
messages: Belongs to the helicase family. RecQ subfamily.

2052056:CTZ24 RS12325
gene id: 2052056:CTZ24_RS12325
uniprot id: A0A6I6AXS6
names: Function
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. SpeA subfamily.
messages: Catalyzes the biosynthesis of agmatine from arginine.

2052056:CTZ24 RS06790
gene id: 2052056:CTZ24_RS06790
uniprot id: A0A6I6AVN6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
messages: Cytoplasm
messages: Homodimer.

2052056:CTZ24 RS20170
gene id: 2052056:CTZ24_RS20170
uniprot id: A0A6I6AZK1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
messages: Cytoplasm
messages: Homotrimer.
messages: In the C-terminal section; belongs to the transferase hexapeptide repeat family.
messages: In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.

2052056:CTZ24 RS14160
gene id: 2052056:CTZ24_RS14160
uniprot id: A0A6I6AZF8
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NapB family.
messages: Binds 2 heme C groups per subunit.
messages: Component of the periplasmic nitrate reductase NapAB complex composed of NapA and NapB.
messages: Electron transfer subunit of the periplasmic nitrate reductase complex NapAB.
messages: Periplasm

2052056:CTZ24 RS02425
gene id: 2052056:CTZ24_RS02425
uniprot id: A0A6I6ANP6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MlaE permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the ABC transporter complex MlaFEDB, which is involved in a phospholipid transport pathway that maintains lipid asymmetry in the outer membrane by retrograde trafficking of phospholipids from the outer membrane to the inner membrane. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (MlaF), two transmembrane proteins (MlaE), two cytoplasmic solute-binding proteins (MlaB) and six periplasmic solute-binding proteins (MlaD).

2052056:CTZ24 RS04950
gene id: 2052056:CTZ24_RS04950
uniprot id: A0A6I6AXV0
names: Similarity
messages: Belongs to the Hha/YmoA/Cnu family.

2052056:CTZ24 RS05020
gene id: 2052056:CTZ24_RS05020
uniprot id: A0A6I6ATT1
names: Subcellular Location Annotation
messages: Cell inner membrane

2052056:CTZ24 RS08720
gene id: 2052056:CTZ24_RS08720
uniprot id: A0A6I6AWL9
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

2052056:CTZ24 RS10950
gene id: 2052056:CTZ24_RS10950
uniprot id: A0A6I6AT42
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phospholipase D family. Cardiolipin synthase subfamily. ClsA sub-subfamily.
messages: Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol.
messages: Cell membrane
messages: Membrane

2052056:CTZ24 RS15235
gene id: 2052056:CTZ24_RS15235
uniprot id: A0A6I6B008
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The enzyme II FruAB PTS system is involved in fructose transport.

2052056:CTZ24 RS18515
gene id: 2052056:CTZ24_RS18515
uniprot id: A0A6I6AX85
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DsrE/TusD family.
messages: Cytoplasm
messages: Heterohexamer, formed by a dimer of trimers. The hexameric TusBCD complex contains 2 copies each of TusB, TusC and TusD. The TusBCD complex interacts with TusE.
messages: Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE.

2052056:CTZ24 RS12455
gene id: 2052056:CTZ24_RS12455
uniprot id: A0A6I6AVG6
names: Similarity
messages: Belongs to the UPF0149 family.

2052056:CTZ24 RS00105
gene id: 2052056:CTZ24_RS00105
uniprot id: A0A6I6AQW7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

2052056:CTZ24 RS02080
gene id: 2052056:CTZ24_RS02080
uniprot id: A0A6I6ANQ3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2052056:CTZ24 RS06025
gene id: 2052056:CTZ24_RS06025
uniprot id: A0A6I6AR95
names: Function
names: Similarity
messages: Belongs to the MoaB/Mog family.
messages: May be involved in the biosynthesis of molybdopterin.

2052056:CTZ24 RS18095
gene id: 2052056:CTZ24_RS18095
uniprot id: A0A6I6B1C2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aromatic acid exporter ArAE (TC 2.A.85) family.
messages: Cell membrane
messages: Forms an efflux pump with AaeA. Could function as a metabolic relief valve, allowing to eliminate certain compounds when they accumulate to high levels in the cell.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2052056:CTZ24 RS09175
gene id: 2052056:CTZ24_RS09175
uniprot id: A0A6I6ASS3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrB/RnfD family.
messages: Cell inner membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

2052056:CTZ24 RS05960
gene id: 2052056:CTZ24_RS05960
uniprot id: A0A6I6AQL3
names: Similarity
messages: Belongs to the ABC transporter superfamily. Drug exporter-2 (TC 3.A.1.117) family.

2052056:CTZ24 RS18830
gene id: 2052056:CTZ24_RS18830
uniprot id: A0A6I6B013
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S54 family.
messages: Cell membrane
messages: Membrane
messages: Rhomboid-type serine protease that catalyzes intramembrane proteolysis.

2052056:CTZ24 RS03755
gene id: 2052056:CTZ24_RS03755
uniprot id: A0A6I6AQU4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. GluQ subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5-dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon.

2052056:CTZ24 RS12810
gene id: 2052056:CTZ24_RS12810
uniprot id: A0A6I6AYT5
names: Function
messages: Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and/or cell division.

2052056:CTZ24 RS14890
gene id: 2052056:CTZ24_RS14890
uniprot id: A0A6I6AZU8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 1 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 13 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.

2052056:CTZ24 RS12450
gene id: 2052056:CTZ24_RS12450
uniprot id: A0A6I6AYN2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division.
messages: Belongs to the ZapA family. Type 1 subfamily.
messages: Cytoplasm
messages: Homodimer. Interacts with FtsZ.

2052056:CTZ24 RS15530
gene id: 2052056:CTZ24_RS15530
uniprot id: A0A6I6B068
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial sugar transferase family.
messages: Membrane

2052056:CTZ24 RS14065
gene id: 2052056:CTZ24_RS14065
uniprot id: A0A6I6AUQ1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

2052056:CTZ24 RS01720
gene id: 2052056:CTZ24_RS01720
uniprot id: A0A6I6AQ47
names: Subcellular Location Annotation
messages: Membrane

2052056:CTZ24 RS18435
gene id: 2052056:CTZ24_RS18435
uniprot id: A0A6I6B152
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

2052056:CTZ24 RS10830
gene id: 2052056:CTZ24_RS10830
uniprot id: A0A6I6AXV2
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

2052056:CTZ24 RS11680
gene id: 2052056:CTZ24_RS11680
uniprot id: A0A6I6AXF0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Membrane

2052056:CTZ24 RS19640
gene id: 2052056:CTZ24_RS19640
uniprot id: A0A6I6AZB7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

2052056:CTZ24 RS03400
gene id: 2052056:CTZ24_RS03400
uniprot id: A0A6I6AX44
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.

2052056:CTZ24 RS15700
gene id: 2052056:CTZ24_RS15700
uniprot id: A0A6I6B3H0
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATP phosphoribosyltransferase family. Long subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Equilibrium between an active dimeric form, an inactive hexameric form and higher aggregates. Interconversion between the various forms is largely reversible and is influenced by the natural substrates and inhibitors of the enzyme.
messages: Feedback inhibited by histidine.

2052056:CTZ24 RS04810
gene id: 2052056:CTZ24_RS04810
uniprot id: A0A6I6ATP2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome c oxidase bacterial subunit 4 family.
messages: Cytochrome bo(3) ubiquinol terminal oxidase is the component of the aerobic respiratory chain of E.coli that predominates when cells are grown at high aeration. Has proton pump activity across the membrane in addition to electron transfer, pumping 2 protons/electron.
messages: Heterooctamer of two A chains, two B chains, two C chains and two D chains.
messages: Membrane

2052056:CTZ24 RS05100
gene id: 2052056:CTZ24_RS05100
uniprot id: A0A6I6AQV6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2052056:CTZ24 RS07155
gene id: 2052056:CTZ24_RS07155
uniprot id: A0A6I6AR75
names: Subcellular Location Annotation
messages: Membrane

2052056:CTZ24 RS17815
gene id: 2052056:CTZ24_RS17815
uniprot id: A0A6I6B0S6
names: Function
names: Similarity
messages: Belongs to the peptidase U62 family.
messages: Probable metalloprotease.

2052056:CTZ24 RS12515
gene id: 2052056:CTZ24_RS12515
uniprot id: A0A6I6AVJ6
names: Similarity
messages: Belongs to the SdhE FAD assembly factor family.

2052056:CTZ24 RS12990
gene id: 2052056:CTZ24_RS12990
uniprot id: A0A6I6AUK3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PAPS reductase family. CysD subfamily.
messages: Heterodimer composed of CysD, the smaller subunit, and CysN.
messages: With CysN forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway. APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD.

2052056:CTZ24 RS08105
gene id: 2052056:CTZ24_RS08105
uniprot id: A0A6I6AWC2
names: Similarity
names: Subunit
messages: Belongs to the Nudix hydrolase family. NudJ subfamily.
messages: Monomer.

2052056:CTZ24 RS05540
gene id: 2052056:CTZ24_RS05540
uniprot id: A0A6I6AQE9
names: Similarity
messages: Belongs to the PhoH family.

2052056:CTZ24 RS16595
gene id: 2052056:CTZ24_RS16595
uniprot id: A0A6I6B046
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliO/MopB family.
messages: Cell membrane

2052056:CTZ24 RS08690
gene id: 2052056:CTZ24_RS08690
uniprot id: A0A6I6AZZ3
names: Similarity
messages: Belongs to the fructosamine kinase family.

2052056:CTZ24 RS00365
gene id: 2052056:CTZ24_RS00365
uniprot id: A0A6I6AV30
names: Subunit
messages: Homotetramer.

2052056:CTZ24 RS14555
gene id: 2052056:CTZ24_RS14555
uniprot id: A0A6I6B3X4
names: Function
names: Similarity
messages: Belongs to the CcmH/CycL/Ccl2/NrfF family.
messages: Possible subunit of a heme lyase.

2052056:CTZ24 RS02620
gene id: 2052056:CTZ24_RS02620
uniprot id: A0A6I6ATF1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

2052056:CTZ24 RS06040
gene id: 2052056:CTZ24_RS06040
uniprot id: A0A6I6AYV8
names: Similarity
names: Subunit
messages: Belongs to the MoaE family.
messages: Heterotetramer of 2 MoaD subunits and 2 MoaE subunits. Also stable as homodimer. The enzyme changes between these two forms during catalysis.

2052056:CTZ24 RS25040
gene id: 2052056:CTZ24_RS25040
uniprot id: A0A6I6B5V2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ACC deaminase/D-cysteine desulfhydrase family.
messages: Catalyzes a cyclopropane ring-opening reaction, the irreversible conversion of 1-aminocyclopropane-1-carboxylate (ACC) to ammonia and alpha-ketobutyrate. Allows growth on ACC as a nitrogen source.
messages: Homotrimer.

2052056:CTZ24 RS11635
gene id: 2052056:CTZ24_RS11635
uniprot id: A0A6I6ATH7
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

2052056:CTZ24 RS06540
gene id: 2052056:CTZ24_RS06540
uniprot id: A0A6I6AS86
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methylthiotransferase family. RimO subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein uS12.
messages: Cytoplasm

2052056:CTZ24 RS13095
gene id: 2052056:CTZ24_RS13095
uniprot id: A0A6I6AUL9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Mediates global changes in gene expression, shifting from rapid growth to stress survival by linking envelope stress, the stringent response and the catabolite repression systems. Usually binds in the 5'-UTR; binding at or near the Shine-Dalgarno sequence prevents ribosome-binding, repressing translation, binding elsewhere in the 5'-UTR can activate translation and/or stabilize the mRNA. Its function is antagonized by small RNA(s).
messages: Belongs to the CsrA/RsmA family.
messages: Cytoplasm
messages: Homodimer; the beta-strands of each monomer intercalate to form a hydrophobic core, while the alpha-helices form wings that extend away from the core.

2052056:CTZ24 RS05065
gene id: 2052056:CTZ24_RS05065
uniprot id: A0A6I6AYB4
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

2052056:CTZ24 RS25995
gene id: 2052056:CTZ24_RS25995
uniprot id: A0A6I6B6P7
names: Subcellular Location Annotation
messages: Membrane

2052056:CTZ24 RS05745
gene id: 2052056:CTZ24_RS05745
uniprot id: A0A6I6AR45
names: Function
names: Similarity
messages: Belongs to the alpha-ketoglutarate dehydrogenase family.
messages: E1 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the decarboxylation of 2-oxoglutarate, the first step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).

2052056:CTZ24 RS09430
gene id: 2052056:CTZ24_RS09430
uniprot id: A0A6I6ASE5
names: Function
names: Similarity
messages: Belongs to the PqqC family.
messages: Ring cyclization and eight-electron oxidation of 3a-(2-amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline-7,9-dicarboxylic-acid to PQQ.

2052056:CTZ24 RS11670
gene id: 2052056:CTZ24_RS11670
uniprot id: A0A6I6B2A5
names: Subunit
messages: Monomer.

2052056:CTZ24 RS05720
gene id: 2052056:CTZ24_RS05720
uniprot id: A0A6I6AU56
names: Similarity
messages: Belongs to the citrate synthase family.

2052056:CTZ24 RS03765
gene id: 2052056:CTZ24_RS03765
uniprot id: A0A6I6AXD6
names: Similarity
messages: Belongs to the SfsA family.

2052056:CTZ24 RS18365
gene id: 2052056:CTZ24_RS18365
uniprot id: A0A6I6AYP5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

2052056:CTZ24 RS18355
gene id: 2052056:CTZ24_RS18355
uniprot id: A0A6I6AYQ5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

2052056:CTZ24 RS08395
gene id: 2052056:CTZ24_RS08395
uniprot id: A0A6I6AVP1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC13A/DASS transporter (TC 2.A.47) family. DIT1 subfamily.
messages: Membrane

2052056:CTZ24 RS18965
gene id: 2052056:CTZ24_RS18965
uniprot id: A0A6I6B6E6
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Homooctamer.

2052056:CTZ24 RS10480
gene id: 2052056:CTZ24_RS10480
uniprot id: A0A6I6AXN5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PNT beta subunit family.
messages: Cell inner membrane
messages: Heterodimer of an alpha and a beta chain.
messages: Membrane
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

2052056:CTZ24 RS01185
gene id: 2052056:CTZ24_RS01185
uniprot id: A0A6I6AN54
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the uroporphyrinogen decarboxylase family.
messages: Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2052056:CTZ24 RS12430
gene id: 2052056:CTZ24_RS12430
uniprot id: A0A6I6AXU8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ribose 5-phosphate isomerase family.
messages: Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
messages: Homodimer.

2052056:CTZ24 RS01285
gene id: 2052056:CTZ24_RS01285
uniprot id: A0A6I6ASW4
names: Similarity
messages: Belongs to the aspartokinase family.

2052056:CTZ24 RS06820
gene id: 2052056:CTZ24_RS06820
uniprot id: A0A6I6AVY0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. Drug exporter-2 (TC 3.A.1.117) family.
messages: Membrane

2052056:CTZ24 RS09170
gene id: 2052056:CTZ24_RS09170
uniprot id: A0A6I6ATR0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RnfG family.
messages: Cell inner membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

2052056:CTZ24 RS00745
gene id: 2052056:CTZ24_RS00745
uniprot id: A0A6I6AVC5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DEAD box helicase family. RhlB subfamily.
messages: Component of the RNA degradosome, which is a multiprotein complex involved in RNA processing and mRNA degradation.
messages: Cytoplasm
messages: DEAD-box RNA helicase involved in RNA degradation. Has RNA-dependent ATPase activity and unwinds double-stranded RNA.

2052056:CTZ24 RS06810
gene id: 2052056:CTZ24_RS06810
uniprot id: A0A6I6AYY2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial histone-like protein family.
messages: Heterodimer of an alpha and a beta chain.
messages: This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.

2052056:CTZ24 RS03850
gene id: 2052056:CTZ24_RS03850
uniprot id: A0A6I6AQB4
names: Similarity
messages: Belongs to the UPF0325 family.

2052056:CTZ24 RS14765
gene id: 2052056:CTZ24_RS14765
uniprot id: A0A6I6AZQ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane

2052056:CTZ24 RS16760
gene id: 2052056:CTZ24_RS16760
uniprot id: A0A6I6B0T2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ACC deaminase/D-cysteine desulfhydrase family.
messages: Catalyzes the alpha,beta-elimination reaction of D-cysteine and of several D-cysteine derivatives. It could be a defense mechanism against D-cysteine.
messages: Homodimer.

2052056:CTZ24 RS12055
gene id: 2052056:CTZ24_RS12055
uniprot id: A0A6I6ATQ7
names: Similarity
messages: Belongs to the bacterial solute-binding protein 9 family.

2052056:CTZ24 RS16575
gene id: 2052056:CTZ24_RS16575
uniprot id: A0A6I6B3V8
names: Function
names: Similarity
messages: Belongs to the RcsA family.
messages: Component of the Rcs signaling system, which controls transcription of numerous genes. Binds to DNA to regulate expression of genes.

2052056:CTZ24 RS04815
gene id: 2052056:CTZ24_RS04815
uniprot id: A0A6I6AQ25
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Cytochrome bo(3) ubiquinol terminal oxidase is the component of the aerobic respiratory chain of E.coli that predominates when cells are grown at high aeration. Has proton pump activity across the membrane in addition to electron transfer, pumping 2 protons/electron.
messages: Heterooctamer of two A chains, two B chains, two C chains and two D chains.
messages: Membrane

2052056:CTZ24 RS13140
gene id: 2052056:CTZ24_RS13140
uniprot id: A0A6I6AYZ0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LuxS family.
messages: Binds 1 Fe cation per subunit.
messages: Homodimer.
messages: Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD).

2052056:CTZ24 RS03470
gene id: 2052056:CTZ24_RS03470
uniprot id: A0A6I6AP79
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEDS family. FtsW subfamily.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Peptidoglycan polymerase that is essential for cell division.

2052056:CTZ24 RS10520
gene id: 2052056:CTZ24_RS10520
uniprot id: A0A6I6B0X2
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Asr family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Periplasm
messages: Proteolytic processing gives rise to the active protein.
messages: Required for growth and/or survival at acidic conditions.

2052056:CTZ24 RS07120
gene id: 2052056:CTZ24_RS07120
uniprot id: A0A6I6ASJ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

2052056:CTZ24 RS03000
gene id: 2052056:CTZ24_RS03000
uniprot id: A0A6I6AQB0
names: Subcellular Location Annotation
messages: Membrane

2052056:CTZ24 RS05190
gene id: 2052056:CTZ24_RS05190
uniprot id: A0A6I6ATW2
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2052056:CTZ24 RS10245
gene id: 2052056:CTZ24_RS10245
uniprot id: A0A6I6AT86
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

2052056:CTZ24 RS06460
gene id: 2052056:CTZ24_RS06460
uniprot id: A0A6I6AUK5
names: Function
names: Similarity
messages: Belongs to the DtxR/MntR family.
messages: In the presence of manganese, represses expression of mntH and mntS. Up-regulates expression of mntP.

2052056:CTZ24 RS18445
gene id: 2052056:CTZ24_RS18445
uniprot id: A0A6I6AWW1
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

2052056:CTZ24 RS13625
gene id: 2052056:CTZ24_RS13625
uniprot id: A0A6I6B2K9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RseB family.
messages: Periplasm

2052056:CTZ24 RS08365
gene id: 2052056:CTZ24_RS08365
uniprot id: A0A6I6ATC9
names: Similarity
messages: Belongs to the glutamine synthetase family.

2052056:CTZ24 RS19825
gene id: 2052056:CTZ24_RS19825
uniprot id: A0A6I6AXN0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.

2052056:CTZ24 RS02400
gene id: 2052056:CTZ24_RS02400
uniprot id: A0A6I6AQ09
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptC family.
messages: Cell inner membrane
messages: Component of the lipopolysaccharide transport and assembly complex. Interacts with LptA and the LptBFG transporter complex.
messages: Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. Facilitates the transfer of LPS from the inner membrane to the periplasmic protein LptA. Could be a docking site for LptA.
messages: Required for the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane.

2052056:CTZ24 RS04690
gene id: 2052056:CTZ24_RS04690
uniprot id: A0A6I6AXQ0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.

2052056:CTZ24 RS05620
gene id: 2052056:CTZ24_RS05620
uniprot id: A0A6I6AU34
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

2052056:CTZ24 RS20150
gene id: 2052056:CTZ24_RS20150
uniprot id: A0A6I6B222
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family. T3SS ATPase subfamily.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has four main subunits: a(1), b(1), b'(1) and c(9-12).
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

2052056:CTZ24 RS05725
gene id: 2052056:CTZ24_RS05725
uniprot id: A0A6I6AQN4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome b560 family.
messages: Membrane
messages: Membrane-anchoring subunit of succinate dehydrogenase (SDH).
messages: Part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur protein, plus two membrane-anchoring proteins, SdhC and SdhD. The complex can form homotrimers.
messages: The heme is bound between the two transmembrane subunits.

2052056:CTZ24 RS10675
gene id: 2052056:CTZ24_RS10675
uniprot id: A0A6I6B0Z7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

2052056:CTZ24 RS07075
gene id: 2052056:CTZ24_RS07075
uniprot id: A0A6I6AW24
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

2052056:CTZ24 RS11485
gene id: 2052056:CTZ24_RS11485
uniprot id: A0A6I6ATE4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoD/SigA subfamily.
messages: Cytoplasm
messages: Interacts transiently with the RNA polymerase catalytic core.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.

2052056:CTZ24 RS18590
gene id: 2052056:CTZ24_RS18590
uniprot id: A0A6I6B001
names: Similarity
messages: Belongs to the UPF0270 family.

2052056:CTZ24 RS09185
gene id: 2052056:CTZ24_RS09185
uniprot id: A0A6I6B092
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfB subfamily.
messages: Binds 3 [4Fe-4S] clusters.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

2052056:CTZ24 RS11820
gene id: 2052056:CTZ24_RS11820
uniprot id: A0A6I6B2E1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
messages: Cytoplasm
messages: Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.

2052056:CTZ24 RS14790
gene id: 2052056:CTZ24_RS14790
uniprot id: A0A6I6AWV8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

2052056:CTZ24 RS19510
gene id: 2052056:CTZ24_RS19510
uniprot id: A0A6I6B1P9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Conversion of NADPH, generated by peripheral catabolic pathways, to NADH, which can enter the respiratory chain for energy generation.
messages: Cytoplasm

2052056:CTZ24 RS25850
gene id: 2052056:CTZ24_RS25850
uniprot id: A0A6I6B1M4
names: Subcellular Location Annotation
messages: Membrane

2052056:CTZ24 RS08255
gene id: 2052056:CTZ24_RS08255
uniprot id: A0A6I6ARW9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)-dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility.
messages: Bacterial flagellum basal body
messages: Belongs to the YcgR family.
messages: Monomer. Interacts with the flagellar basal bodies.

2052056:CTZ24 RS01420
gene id: 2052056:CTZ24_RS01420
uniprot id: A0A6I6AP24
names: Similarity
messages: Belongs to the ABC transporter superfamily. Drug exporter-2 (TC 3.A.1.117) family.

2052056:CTZ24 RS06505
gene id: 2052056:CTZ24_RS06505
uniprot id: A0A6I6AVS2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal stress protein A family.
messages: Cytoplasm

2052056:CTZ24 RS06765
gene id: 2052056:CTZ24_RS06765
uniprot id: A0A6I6AZE0
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. YcaD (TC 2.A.1.26) family.
messages: Cell inner membrane
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

2052056:CTZ24 RS07810
gene id: 2052056:CTZ24_RS07810
uniprot id: A0A6I6AT37
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FlgA family.
messages: Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly.
messages: Periplasm

2052056:CTZ24 RS17960
gene id: 2052056:CTZ24_RS17960
uniprot id: A0A6I6AYI0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.
messages: Belongs to the RNR ribonuclease family. RNase R subfamily.
messages: Cytoplasm
messages: Monomer.

2052056:CTZ24 RS13345
gene id: 2052056:CTZ24_RS13345
uniprot id: A0A6I6AUQ5
names: Cofactor
messages: Binds 1 zinc ion per subunit.

2052056:CTZ24 RS05035
gene id: 2052056:CTZ24_RS05035
uniprot id: A0A6I6B5L9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

2052056:CTZ24 RS11005
gene id: 2052056:CTZ24_RS11005
uniprot id: A0A6I6AT52
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone-like protein H-NS family.
messages: nucleoid

2052056:CTZ24 RS01460
gene id: 2052056:CTZ24_RS01460
uniprot id: A0A6I6ASU2
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the gamma-glutamyltransferase family.
messages: Cleaved by autocatalysis into a large and a small subunit.
messages: This enzyme consists of two polypeptide chains, which are synthesized in precursor form from a single polypeptide.

2052056:CTZ24 RS01050
gene id: 2052056:CTZ24_RS01050
uniprot id: A0A6I6ARB8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TrkH potassium transport family.
messages: Cell inner membrane
messages: Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA.
messages: Membrane

2052056:CTZ24 RS20165
gene id: 2052056:CTZ24_RS20165
uniprot id: A0A6I6B2B0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

2052056:CTZ24 RS11310
gene id: 2052056:CTZ24_RS11310
uniprot id: A0A6I6B216
names: Subcellular Location Annotation
messages: Cytoplasm

2052056:CTZ24 RS00885
gene id: 2052056:CTZ24_RS00885
uniprot id: A0A6I6AR93
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Mediates influx of magnesium ions.
messages: Membrane

2052056:CTZ24 RS03830
gene id: 2052056:CTZ24_RS03830
uniprot id: A0A6I6APE6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dGTPase family. Type 1 subfamily.
messages: Homotetramer.
messages: dGTPase preferentially hydrolyzes dGTP over the other canonical NTPs.

2052056:CTZ24 RS08235
gene id: 2052056:CTZ24_RS08235
uniprot id: A0A6I6B0A7
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

2052056:CTZ24 RS01295
gene id: 2052056:CTZ24_RS01295
uniprot id: A0A6I6AN39
names: Subcellular Location Annotation
messages: Membrane

2052056:CTZ24 RS07595
gene id: 2052056:CTZ24_RS07595
uniprot id: A0A6I6AS04
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

2052056:CTZ24 RS01120
gene id: 2052056:CTZ24_RS01120
uniprot id: A0A6I6AST5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NusG family.
messages: Monomer. Interacts with the transcription termination factor Rho and with RNA polymerase.
messages: Participates in transcription elongation, termination and antitermination. In the absence of Rho, increases the rate of transcription elongation by the RNA polymerase (RNAP), probably by partially suppressing pausing. In the presence of Rho, modulates most Rho-dependent termination events by interacting with the RNAP to render the complex more susceptible to the termination activity of Rho. May be required to overcome a kinetic limitation of Rho to function at certain terminators. Also involved in ribosomal RNA transcriptional antitermination.

2052056:CTZ24 RS08215
gene id: 2052056:CTZ24_RS08215
uniprot id: A0A6I6ASB8
names: Similarity
messages: Belongs to the SorC transcriptional regulatory family.

2052056:CTZ24 RS05795
gene id: 2052056:CTZ24_RS05795
uniprot id: A0A6I6AR56
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ExbD/TolR family.
messages: Cell inner membrane
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity. Required, with TolQ, for the proton motive force-dependent activation of TolA and for TolA-Pal interaction.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

2052056:CTZ24 RS06490
gene id: 2052056:CTZ24_RS06490
uniprot id: A0A6I6AS77
names: Similarity
messages: Belongs to the ABC transporter superfamily. Drug exporter-2 (TC 3.A.1.117) family.

2052056:CTZ24 RS09190
gene id: 2052056:CTZ24_RS09190
uniprot id: A0A6I6B0S8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell inner membrane
messages: Membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

2052056:CTZ24 RS18455
gene id: 2052056:CTZ24_RS18455
uniprot id: A0A6I6AYS1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

2052056:CTZ24 RS14265
gene id: 2052056:CTZ24_RS14265
uniprot id: A0A6I6AYX3
names: Subcellular Location Annotation
messages: Cell inner membrane

2052056:CTZ24 RS07135
gene id: 2052056:CTZ24_RS07135
uniprot id: A0A6I6AW32
names: Function
names: Similarity
messages: Belongs to the RutC family.
messages: Involved in pyrimidine catabolism. Catalyzes the deamination of 3-aminoacrylate to malonic semialdehyde, a reaction that can also occur spontaneously. RutC may facilitate the reaction and modulate the metabolic fitness, rather than catalyzing essential functions.

2052056:CTZ24 RS07565
gene id: 2052056:CTZ24_RS07565
uniprot id: A0A6I6AWA3
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

2052056:CTZ24 RS03860
gene id: 2052056:CTZ24_RS03860
uniprot id: A0A6I6B292
names: Activity Regulation
names: Domain
names: Function
names: Similarity
messages: Belongs to the GlnD family.
messages: Has four distinct domains: an N-terminal nucleotidyltransferase (NT) domain responsible for UTase activity, a central HD domain that encodes UR activity, and two C-terminal ACT domains that seem to have a role in glutamine sensing.
messages: Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen metabolism.
messages: Uridylyltransferase (UTase) activity is inhibited by glutamine, while glutamine activates uridylyl-removing (UR) activity.

2052056:CTZ24 RS15240
gene id: 2052056:CTZ24_RS15240
uniprot id: A0A6I6AX34
names: Function
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.
messages: Catalyzes the ATP-dependent phosphorylation of fructose-l-phosphate to fructose-l,6-bisphosphate.

2052056:CTZ24 RS20135
gene id: 2052056:CTZ24_RS20135
uniprot id: A0A6I6B5H9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Membrane

2052056:CTZ24 RS08835
gene id: 2052056:CTZ24_RS08835
uniprot id: A0A6I6AWN7
names: Function
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.
messages: Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine.

2052056:CTZ24 RS16750
gene id: 2052056:CTZ24_RS16750
uniprot id: A0A6I6AW23
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sigma-70 factor family. FliA subfamily.
messages: Cytoplasm
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor controls the expression of flagella-related genes.

2052056:CTZ24 RS15150
gene id: 2052056:CTZ24_RS15150
uniprot id: A0A6I6B397
names: Similarity
messages: Belongs to the UPF0352 family.

2052056:CTZ24 RS02590
gene id: 2052056:CTZ24_RS02590
uniprot id: A0A6I6ASC2
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

2052056:CTZ24 RS02130
gene id: 2052056:CTZ24_RS02130
uniprot id: A0A6I6ANR2
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

2052056:CTZ24 RS00915
gene id: 2052056:CTZ24_RS00915
uniprot id: A0A6I6AP75
names: Similarity
messages: Belongs to the Rht family.

2052056:CTZ24 RS06700
gene id: 2052056:CTZ24_RS06700
uniprot id: A0A6I6ARL5
names: Subcellular Location Annotation
messages: Cytoplasm

2052056:CTZ24 RS16190
gene id: 2052056:CTZ24_RS16190
uniprot id: A0A6I6AW26
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

2052056:CTZ24 RS09030
gene id: 2052056:CTZ24_RS09030
uniprot id: A0A6I6B065
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

2052056:CTZ24 RS11020
gene id: 2052056:CTZ24_RS11020
uniprot id: A0A6I6ATL5
names: Similarity
messages: Belongs to the UDPGP type 2 family.

2052056:CTZ24 RS05855
gene id: 2052056:CTZ24_RS05855
uniprot id: A0A6I6AS37
names: Subcellular Location Annotation
messages: Membrane

2052056:CTZ24 RS19155
gene id: 2052056:CTZ24_RS19155
uniprot id: A0A6I6B1V0
names: Subcellular Location Annotation
messages: Membrane

2052056:CTZ24 RS02465
gene id: 2052056:CTZ24_RS02465
uniprot id: A0A6I6ATP0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

2052056:CTZ24 RS14150
gene id: 2052056:CTZ24_RS14150
uniprot id: A0A6I6B2U4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NapD family.
messages: Chaperone for NapA, the catalytic subunit of the periplasmic nitrate reductase. It binds directly and specifically to the twin-arginine signal peptide of NapA, preventing premature interaction with the Tat translocase and premature export.
messages: Cytoplasm
messages: Interacts with the cytoplasmic NapA precursor.

2052056:CTZ24 RS18530
gene id: 2052056:CTZ24_RS18530
uniprot id: A0A6I6B660
names: Similarity
messages: Belongs to the SlyX family.

2052056:CTZ24 RS02335
gene id: 2052056:CTZ24_RS02335
uniprot id: A0A6I6ANU9
names: Similarity
messages: Belongs to the GST superfamily. HSP26 family.

2052056:CTZ24 RS19230
gene id: 2052056:CTZ24_RS19230
uniprot id: A0A6I6B6I8
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fluoride channel Fluc/FEX (TC 1.A.43) family.
messages: Cell membrane
messages: Fluoride-specific ion channel. Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane
messages: Na(+) is not transported, but it plays an essential structural role and its presence is essential for fluoride channel function.

2052056:CTZ24 RS23460
gene id: 2052056:CTZ24_RS23460
uniprot id: A0A6I6B812
names: Similarity
messages: Belongs to the ABC transporter superfamily. Drug exporter-2 (TC 3.A.1.117) family.

2052056:CTZ24 RS01010
gene id: 2052056:CTZ24_RS01010
uniprot id: A0A6I6APS1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RfaH family.
messages: Enhances distal genes transcription elongation in a specialized subset of operons that encode extracytoplasmic components. RfaH is recruited into a multi-component RNA polymerase complex by the ops element, which is a short conserved DNA sequence located downstream of the main promoter of these operons. Once bound, RfaH suppresses pausing and inhibits Rho-dependent and intrinsic termination at a subset of sites. Termination signals are bypassed, which allows complete synthesis of long RNA chains.
messages: Interacts with both the nontemplate DNA and the RNA polymerase (RNAP).

2052056:CTZ24 RS15225
gene id: 2052056:CTZ24_RS15225
uniprot id: A0A6I6AVA9
names: Similarity
messages: Belongs to the elongation factor P family.

2052056:CTZ24 RS15535
gene id: 2052056:CTZ24_RS15535
uniprot id: A0A6I6AX88
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BexD/CtrA/VexA family.
messages: Cell outer membrane
messages: Membrane

2052056:CTZ24 RS01660
gene id: 2052056:CTZ24_RS01660
uniprot id: A0A6I6ASY1
names: Similarity
messages: Belongs to the transposase 8 family.

2052056:CTZ24 RS07770
gene id: 2052056:CTZ24_RS07770
uniprot id: A0A6I6ASV8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. DHA1 family. MdtH (TC 2.A.1.2.21) subfamily.
messages: Cell membrane
messages: Membrane

2052056:CTZ24 RS12155
gene id: 2052056:CTZ24_RS12155
uniprot id: A0A6I6B2K2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

2052056:CTZ24 RS13270
gene id: 2052056:CTZ24_RS13270
uniprot id: A0A6I6AUC9
names: Subcellular Location Annotation
messages: Membrane

2052056:CTZ24 RS18460
gene id: 2052056:CTZ24_RS18460
uniprot id: A0A6I6AX77
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

2052056:CTZ24 RS14010
gene id: 2052056:CTZ24_RS14010
uniprot id: A0A6I6AZF5
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
messages: Allosterically activated by GTP.
messages: Belongs to the UPRTase family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.
messages: Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.

2052056:CTZ24 RS02920
gene id: 2052056:CTZ24_RS02920
uniprot id: A0A6I6ASI2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NlpA lipoprotein family.
messages: Membrane

2052056:CTZ24 RS07865
gene id: 2052056:CTZ24_RS07865
uniprot id: A0A6I6AS56
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Secreted

2052056:CTZ24 RS10685
gene id: 2052056:CTZ24_RS10685
uniprot id: A0A6I6AXS1
names: Similarity
messages: Belongs to the ABC transporter superfamily. Drug exporter-2 (TC 3.A.1.117) family.

2052056:CTZ24 RS18395
gene id: 2052056:CTZ24_RS18395
uniprot id: A0A6I6AWV5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

2052056:CTZ24 RS01300
gene id: 2052056:CTZ24_RS01300
uniprot id: A0A6I6AN72
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

2052056:CTZ24 RS09250
gene id: 2052056:CTZ24_RS09250
uniprot id: A0A6I6AW38
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

2052056:CTZ24 RS13030
gene id: 2052056:CTZ24_RS13030
uniprot id: A0A6I6AU60
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SurE nucleotidase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Cytoplasm
messages: Nucleotidase with a broad substrate specificity as it can dephosphorylate various ribo- and deoxyribonucleoside 5'-monophosphates and ribonucleoside 3'-monophosphates with highest affinity to 3'-AMP. Also hydrolyzes polyphosphate (exopolyphosphatase activity) with the preference for short-chain-length substrates (P20-25). Might be involved in the regulation of dNTP and NTP pools, and in the turnover of 3'-mononucleotides produced by numerous intracellular RNases (T1, T2, and F) during the degradation of various RNAs.

2052056:CTZ24 RS09440
gene id: 2052056:CTZ24_RS09440
uniprot id: A0A6I6ATW3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. PqqE family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the cross-linking of a glutamate residue and a tyrosine residue in the PqqA protein as part of the biosynthesis of pyrroloquinoline quinone (PQQ).
messages: Interacts with PqqD. The interaction is necessary for activity of PqqE.

2052056:CTZ24 RS01600
gene id: 2052056:CTZ24_RS01600
uniprot id: A0A6I6ANC4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

2052056:CTZ24 RS02560
gene id: 2052056:CTZ24_RS02560
uniprot id: A0A6I6B270
names: Similarity
messages: Belongs to the peptidase S13 family.

2052056:CTZ24 RS01530
gene id: 2052056:CTZ24_RS01530
uniprot id: A0A6I6AVY6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UbiC family.
messages: Cytoplasm
messages: Monomer.
messages: Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4-hydroxybenzoate (4HB) for the ubiquinone pathway.

2052056:CTZ24 RS20155
gene id: 2052056:CTZ24_RS20155
uniprot id: A0A6I6AXV1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

2052056:CTZ24 RS00850
gene id: 2052056:CTZ24_RS00850
uniprot id: A0A6I6APP0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenylyl cyclase class-1 family.
messages: Cytoplasm

2052056:CTZ24 RS23455
gene id: 2052056:CTZ24_RS23455
uniprot id: A0A6I6B2M5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the histidinol dehydrogenase family.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.
messages: Homodimer.

2052056:CTZ24 RS12970
gene id: 2052056:CTZ24_RS12970
uniprot id: A0A6I6AU81
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAPS reductase family. CysH subfamily.
messages: Catalyzes the formation of sulfite from phosphoadenosine 5'-phosphosulfate (PAPS) using thioredoxin as an electron donor.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2052056:CTZ24 RS14855
gene id: 2052056:CTZ24_RS14855
uniprot id: A0A6I6B350
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2052056:CTZ24 RS19895
gene id: 2052056:CTZ24_RS19895
uniprot id: A0A6I6AZG2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

2052056:CTZ24 RS13735
gene id: 2052056:CTZ24_RS13735
uniprot id: A0A6I6AZ89
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.

2052056:CTZ24 RS15515
gene id: 2052056:CTZ24_RS15515
uniprot id: A0A6I6AZK7
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dCTP deaminase family.
messages: Catalyzes the deamination of dCTP to dUTP.
messages: Homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2052056:CTZ24 RS00600
gene id: 2052056:CTZ24_RS00600
uniprot id: A0A6I6ASK0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

2052056:CTZ24 RS02205
gene id: 2052056:CTZ24_RS02205
uniprot id: A0A6I6AWA1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Cell inner membrane
messages: Membrane

2052056:CTZ24 RS16630
gene id: 2052056:CTZ24_RS16630
uniprot id: A0A6I6B3W6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliH family.
messages: Cytoplasm
messages: Needed for flagellar regrowth and assembly.

2052056:CTZ24 RS05840
gene id: 2052056:CTZ24_RS05840
uniprot id: A0A6I6AQQ4
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MGMT family.
messages: Cytoplasm
messages: Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
messages: This enzyme catalyzes only one turnover and therefore is not strictly catalytic. According to one definition, an enzyme is a biocatalyst that acts repeatedly and over many reaction cycles.

2052056:CTZ24 RS07755
gene id: 2052056:CTZ24_RS07755
uniprot id: A0A6I6AW45
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
messages: Homodimer.

2052056:CTZ24 RS15175
gene id: 2052056:CTZ24_RS15175
uniprot id: A0A6I6AVA1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Bcr/CmlA family.
messages: Cell inner membrane
messages: Membrane

2052056:CTZ24 RS01305
gene id: 2052056:CTZ24_RS01305
uniprot id: A0A6I6ASR1
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2052056:CTZ24 RS00880
gene id: 2052056:CTZ24_RS00880
uniprot id: A0A6I6ASP7
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

2052056:CTZ24 RS05160
gene id: 2052056:CTZ24_RS05160
uniprot id: A0A6I6ARS3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)- to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Homodimer.

2052056:CTZ24 RS05435
gene id: 2052056:CTZ24_RS05435
uniprot id: A0A6I6AUY2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

2052056:CTZ24 RS03155
gene id: 2052056:CTZ24_RS03155
uniprot id: A0A6I6ATQ5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TrpR family.
messages: Cytoplasm
messages: Homodimer.
messages: This protein is an aporepressor. When complexed with L-tryptophan it binds the operator region of the trp operon (5'-ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region.

2052056:CTZ24 RS16990
gene id: 2052056:CTZ24_RS16990
uniprot id: A0A6I6AWH0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type III secretion exporter family.
messages: Cell membrane
messages: Membrane
messages: Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

2052056:CTZ24 RS14100
gene id: 2052056:CTZ24_RS14100
uniprot id: A0A6I6B3Q5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M20A family. DapE subfamily.
messages: Binds 2 Zn(2+) or Co(2+) ions per subunit.
messages: Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls.
messages: Homodimer.

2052056:CTZ24 RS15210
gene id: 2052056:CTZ24_RS15210
uniprot id: A0A6I6B483
names: Similarity
messages: Belongs to the peptidase C40 family.

2052056:CTZ24 RS19695
gene id: 2052056:CTZ24_RS19695
uniprot id: A0A6I6AXT3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecB family.
messages: Cytoplasm
messages: Homotetramer, a dimer of dimers. One homotetramer interacts with 1 SecA dimer.
messages: One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA.

2052056:CTZ24 RS11550
gene id: 2052056:CTZ24_RS11550
uniprot id: A0A6I6AY57
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DHBP synthase family.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Homodimer.

2052056:CTZ24 RS15915
gene id: 2052056:CTZ24_RS15915
uniprot id: A0A6I6B3K3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

2052056:CTZ24 RS04000
gene id: 2052056:CTZ24_RS04000
uniprot id: A0A6I6APN7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RcsF family.
messages: Cell outer membrane
messages: Essential component of the Rcs signaling system, which controls transcription of numerous genes. Plays a role in signal transduction from the cell surface to the histidine kinase RcsC. May detect outer membrane defects.

2052056:CTZ24 RS07655
gene id: 2052056:CTZ24_RS07655
uniprot id: A0A6I6AZD7
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

2052056:CTZ24 RS18410
gene id: 2052056:CTZ24_RS18410
uniprot id: A0A6I6AX65
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

2052056:CTZ24 RS25795
gene id: 2052056:CTZ24_RS25795
uniprot id: A0A6I6B3D6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

2052056:CTZ24 RS19050
gene id: 2052056:CTZ24_RS19050
uniprot id: A0A6I6AZ26
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family. Pit subfamily.
messages: Membrane

2052056:CTZ24 RS06190
gene id: 2052056:CTZ24_RS06190
uniprot id: A0A6I6AYY9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

2052056:CTZ24 RS18835
gene id: 2052056:CTZ24_RS18835
uniprot id: A0A6I6B5Y3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GlpE family.
messages: Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide.
messages: Cytoplasm

2052056:CTZ24 RS15755
gene id: 2052056:CTZ24_RS15755
uniprot id: A0A6I6B3H8
names: Subcellular Location Annotation
messages: Membrane

2052056:CTZ24 RS08035
gene id: 2052056:CTZ24_RS08035
uniprot id: A0A6I6AWI8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. Drug exporter-2 (TC 3.A.1.117) family.
messages: Belongs to the ABC transporter superfamily. Lipoprotein translocase (TC 3.A.1.125) family.
messages: Cell inner membrane
messages: Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner.
messages: The complex is composed of two ATP-binding proteins (LolD) and two transmembrane proteins (LolC and LolE).

2052056:CTZ24 RS26255
gene id: 2052056:CTZ24_RS26255
uniprot id: A0A6I6B1K7
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

2052056:CTZ24 RS11290
gene id: 2052056:CTZ24_RS11290
uniprot id: A0A6I6AUW1
names: Subcellular Location Annotation
messages: Membrane

2052056:CTZ24 RS00435
gene id: 2052056:CTZ24_RS00435
uniprot id: A0A6I6AR14
names: Cofactor
names: Function
messages: Binds 4 [4Fe-4S] clusters per subunit.
messages: The beta chain is an electron transfer unit containing 4 cysteine clusters involved in the formation of iron-sulfur centers.

2052056:CTZ24 RS02410
gene id: 2052056:CTZ24_RS02410
uniprot id: A0A6I6AWH5
names: Similarity
names: Subunit
messages: Belongs to the SIS family. GutQ/KpsF subfamily.
messages: Homotetramer.

2052056:CTZ24 RS06440
gene id: 2052056:CTZ24_RS06440
uniprot id: A0A6I6AS68
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Dps family.
messages: Cytoplasm
messages: During stationary phase, binds the chromosome non-specifically, forming a highly ordered and stable dps-DNA co-crystal within which chromosomal DNA is condensed and protected from diverse damages. It protects DNA from oxidative damage by sequestering intracellular Fe(2+) ion and storing it in the form of Fe(3+) oxyhydroxide mineral, which can be released after reduction. One hydrogen peroxide oxidizes two Fe(2+) ions, which prevents hydroxyl radical production by the Fenton reaction.
messages: Homododecamer. The 12 subunits form a hollow sphere into which the mineral iron core of up to 500 Fe(3+) can be deposited.

2052056:CTZ24 RS13555
gene id: 2052056:CTZ24_RS13555
uniprot id: A0A6I6AZ77
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

2052056:CTZ24 RS25420
gene id: 2052056:CTZ24_RS25420
uniprot id: A0A6I6B193
names: Similarity
messages: Belongs to the ABC transporter superfamily. Drug exporter-2 (TC 3.A.1.117) family.

2052056:CTZ24 RS08740
gene id: 2052056:CTZ24_RS08740
uniprot id: A0A6I6ATE1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial histone-like protein family.
messages: Heterodimer of an alpha and a beta chain.
messages: This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.

2052056:CTZ24 RS06075
gene id: 2052056:CTZ24_RS06075
uniprot id: A0A6I6ARA5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DEAD box helicase family. RhlE subfamily.
messages: Cytoplasm
messages: DEAD-box RNA helicase involved in ribosome assembly. Has RNA-dependent ATPase activity and unwinds double-stranded RNA.

2052056:CTZ24 RS06530
gene id: 2052056:CTZ24_RS06530
uniprot id: A0A6I6ASF9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

2052056:CTZ24 RS14615
gene id: 2052056:CTZ24_RS14615
uniprot id: A0A6I6AZM5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

2052056:CTZ24 RS20095
gene id: 2052056:CTZ24_RS20095
uniprot id: A0A6I6B2F1
names: Similarity
names: Subunit
messages: Belongs to the ViaA family.
messages: Possible formation of a ternary complex RavA-ViaA-CadA.

2052056:CTZ24 RS19820
gene id: 2052056:CTZ24_RS19820
uniprot id: A0A6I6B1V6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the nucleoid occlusion factor SlmA family.
messages: Homodimer. Interacts with FtsZ.
messages: Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid. Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers. SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions.
messages: nucleoid

2052056:CTZ24 RS14520
gene id: 2052056:CTZ24_RS14520
uniprot id: A0A6I6AZM9
names: Similarity
messages: Belongs to the ABC transporter superfamily. Drug exporter-2 (TC 3.A.1.117) family.

2052056:CTZ24 RS08525
gene id: 2052056:CTZ24_RS08525
uniprot id: A0A6I6ASG8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Cell inner membrane
messages: Membrane

2052056:CTZ24 RS02950
gene id: 2052056:CTZ24_RS02950
uniprot id: A0A6I6AQA3
names: Subcellular Location Annotation
messages: Membrane

2052056:CTZ24 RS09770
gene id: 2052056:CTZ24_RS09770
uniprot id: A0A6I6B0J3
names: Similarity
messages: Belongs to the MbcT/ParT/Res family.

2052056:CTZ24 RS14900
gene id: 2052056:CTZ24_RS14900
uniprot id: A0A6I6AVG7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 6 family.
messages: Cell membrane
messages: Composed of 13 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

2052056:CTZ24 RS18845
gene id: 2052056:CTZ24_RS18845
uniprot id: A0A6I6AXE5
names: Function
names: Similarity
messages: Belongs to the IolE/MocC family.
messages: Catalyzes the dehydration of inosose (2-keto-myo-inositol, 2KMI or 2,4,6/3,5-pentahydroxycyclohexanone) to 3D-(3,5/4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi-inositol).

2052056:CTZ24 RS01850
gene id: 2052056:CTZ24_RS01850
uniprot id: A0A6I6ATC7
names: Cofactor
messages: Binds 3 heme c groups covalently per subunit.

2052056:CTZ24 RS00540
gene id: 2052056:CTZ24_RS00540
uniprot id: A0A6I6ASJ0
names: Similarity
messages: Belongs to the ABC transporter superfamily. Drug exporter-2 (TC 3.A.1.117) family.

2052056:CTZ24 RS14865
gene id: 2052056:CTZ24_RS14865
uniprot id: A0A6I6AZS1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 20 kDa subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Cell membrane
messages: NDH-1 is composed of 13 different subunits. Subunits NuoB, CD, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

2052056:CTZ24 RS04040
gene id: 2052056:CTZ24_RS04040
uniprot id: A0A6I6AXL4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2052056:CTZ24 RS03295
gene id: 2052056:CTZ24_RS03295
uniprot id: A0A6I6AX17
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

2052056:CTZ24 RS09130
gene id: 2052056:CTZ24_RS09130
uniprot id: A0A6I6B082
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family. DtpA subfamily.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Proton-dependent permease that transports di- and tripeptides.

2052056:CTZ24 RS02770
gene id: 2052056:CTZ24_RS02770
uniprot id: A0A6I6AP31
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M17 family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm
messages: Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.

2052056:CTZ24 RS19425
gene id: 2052056:CTZ24_RS19425
uniprot id: A0A6I6AZ70
names: Function
names: Similarity
names: Subunit
messages: Belongs to the serine/threonine dehydratase family.
messages: Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.
messages: Homotetramer.

2052056:CTZ24 RS13380
gene id: 2052056:CTZ24_RS13380
uniprot id: A0A6I6AUC5
names: Similarity
messages: Belongs to the ABC transporter superfamily. Drug exporter-2 (TC 3.A.1.117) family.

2052056:CTZ24 RS05105
gene id: 2052056:CTZ24_RS05105
uniprot id: A0A6I6ARJ4
names: Similarity
messages: Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily.

2052056:CTZ24 RS03495
gene id: 2052056:CTZ24_RS03495
uniprot id: A0A6I6AQP5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.
messages: Cell membrane
messages: Self-interacts. Interacts with FtsZ.

2052056:CTZ24 RS14070
gene id: 2052056:CTZ24_RS14070
uniprot id: A0A6I6AZG4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamC family.
messages: Cell outer membrane
messages: Part of the Bam complex, which is composed of the outer membrane protein BamA, and four lipoproteins BamB, BamC, BamD and BamE.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

2052056:CTZ24 RS14515
gene id: 2052056:CTZ24_RS14515
uniprot id: A0A6I6AUX5
names: Subcellular Location Annotation
messages: Membrane

2052056:CTZ24 RS02640
gene id: 2052056:CTZ24_RS02640
uniprot id: A0A6I6AWJ6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Component of the RNA degradosome, which is a multiprotein complex involved in RNA processing and mRNA degradation.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

2052056:CTZ24 RS10445
gene id: 2052056:CTZ24_RS10445
uniprot id: A0A6I6ASW6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DoxX family.
messages: Membrane

2052056:CTZ24 RS05945
gene id: 2052056:CTZ24_RS05945
uniprot id: A0A6I6AVI3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: AcrA-AcrB-AcrZ-TolC is a drug efflux protein complex with a broad substrate specificity. This protein binds to AcrB and is required for efflux of some but not all substrates, suggesting it may influence the specificity of drug export.
messages: Belongs to the AcrZ family.
messages: Cell membrane
messages: Part of the AcrA-AcrB-AcrZ-TolC efflux pump, interacts directly with AcrB.

2052056:CTZ24 RS11510
gene id: 2052056:CTZ24_RS11510
uniprot id: A0A6I6ATU0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DHNA family.
messages: Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin.
messages: Homooctamer.

2052056:CTZ24 RS15275
gene id: 2052056:CTZ24_RS15275
uniprot id: A0A6I6AVB7
names: Similarity
messages: Belongs to the ABC transporter superfamily. Drug exporter-2 (TC 3.A.1.117) family.

2052056:CTZ24 RS19280
gene id: 2052056:CTZ24_RS19280
uniprot id: A0A6I6B6J8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

2052056:CTZ24 RS05320
gene id: 2052056:CTZ24_RS05320
uniprot id: A0A6I6ATY1
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

2052056:CTZ24 RS18140
gene id: 2052056:CTZ24_RS18140
uniprot id: A0A6I6B5Y8
names: Function
names: Similarity
messages: Belongs to the MreC family.
messages: Involved in formation and maintenance of cell shape.

2052056:CTZ24 RS01965
gene id: 2052056:CTZ24_RS01965
uniprot id: A0A6I6ARZ7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane
messages: Part of the ABC transporter complex UgpBAEC involved in sn-glycerol-3-phosphate (G3P) import. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (UgpC), two transmembrane proteins (UgpA and UgpE) and a solute-binding protein (UgpB).

2052056:CTZ24 RS24180
gene id: 2052056:CTZ24_RS24180
uniprot id: A0A6I6B2D0
names: Subcellular Location Annotation
messages: Membrane

2052056:CTZ24 RS18390
gene id: 2052056:CTZ24_RS18390
uniprot id: A0A6I6AWX0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

2052056:CTZ24 RS06735
gene id: 2052056:CTZ24_RS06735
uniprot id: A0A6I6AQZ6
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

2052056:CTZ24 RS02385
gene id: 2052056:CTZ24_RS02385
uniprot id: A0A6I6ATB1
names: Function
names: Similarity
messages: Belongs to the sigma-54 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

2052056:CTZ24 RS05455
gene id: 2052056:CTZ24_RS05455
uniprot id: A0A6I6AY50
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RlpA family.
messages: Cell membrane
messages: Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides.

2052056:CTZ24 RS11695
gene id: 2052056:CTZ24_RS11695
uniprot id: A0A6I6AY90
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

2052056:CTZ24 RS19210
gene id: 2052056:CTZ24_RS19210
uniprot id: A0A6I6AZ47
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2052056:CTZ24 RS03460
gene id: 2052056:CTZ24_RS03460
uniprot id: A0A6I6AU64
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane
messages: Membrane

2052056:CTZ24 RS19070
gene id: 2052056:CTZ24_RS19070
uniprot id: A0A6I6B6G7
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

2052056:CTZ24 RS18220
gene id: 2052056:CTZ24_RS18220
uniprot id: A0A6I6AWU2
names: Function
names: Similarity
names: Subunit
messages: Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters.
messages: Belongs to the transcriptional regulatory Fis family.
messages: Homodimer.

2052056:CTZ24 RS11540
gene id: 2052056:CTZ24_RS11540
uniprot id: A0A6I6ATF4
names: Function
names: Similarity
names: Subunit
messages: Catalyzes the ADP transfer from ATP to D-glycero-beta-D-manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose.
messages: Catalyzes the phosphorylation of D-glycero-D-manno-heptose 7-phosphate at the C-1 position to selectively form D-glycero-beta-D-manno-heptose-1,7-bisphosphate.
messages: Homodimer.
messages: In the C-terminal section; belongs to the cytidylyltransferase family.
messages: In the N-terminal section; belongs to the carbohydrate kinase PfkB family.

2052056:CTZ24 RS10970
gene id: 2052056:CTZ24_RS10970
uniprot id: A0A6I6ATK7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

2052056:CTZ24 RS04790
gene id: 2052056:CTZ24_RS04790
uniprot id: A0A6I6AXS0
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

2052056:CTZ24 RS00085
gene id: 2052056:CTZ24_RS00085
uniprot id: A0A6I6ANT4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RnpA family.
messages: Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.
messages: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.

2052056:CTZ24 RS01500
gene id: 2052056:CTZ24_RS01500
uniprot id: A0A6I6ANA5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

2052056:CTZ24 RS17915
gene id: 2052056:CTZ24_RS17915
uniprot id: A0A6I6B4F2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein bS6.

2052056:CTZ24 RS04805
gene id: 2052056:CTZ24_RS04805
uniprot id: A0A6I6AY43
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
messages: Carbon 2 of the heme B porphyrin ring is defined according to the Fischer nomenclature.
messages: Cell membrane
messages: Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
messages: Membrane

2052056:CTZ24 RS06945
gene id: 2052056:CTZ24_RS06945
uniprot id: A0A6I6ASP1
names: Subcellular Location Annotation
messages: Membrane

2052056:CTZ24 RS01520
gene id: 2052056:CTZ24_RS01520
uniprot id: A0A6I6API8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PsiE family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

2052056:CTZ24 RS13045
gene id: 2052056:CTZ24_RS13045
uniprot id: A0A6I6AUL0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoS subfamily.
messages: Cytoplasm
messages: Interacts with the RNA polymerase core enzyme.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the master transcriptional regulator of the stationary phase and the general stress response.

2052056:CTZ24 RS17990
gene id: 2052056:CTZ24_RS17990
uniprot id: A0A6I6AWN5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

2052056:CTZ24 RS02140
gene id: 2052056:CTZ24_RS02140
uniprot id: A0A6I6AQC6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2052056:CTZ24 RS19675
gene id: 2052056:CTZ24_RS19675
uniprot id: A0A6I6AXJ9
names: Subcellular Location Annotation
messages: Cell inner membrane

2052056:CTZ24 RS05785
gene id: 2052056:CTZ24_RS05785
uniprot id: A0A6I6AV41
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

2052056:CTZ24 RS02595
gene id: 2052056:CTZ24_RS02595
uniprot id: A0A6I6ANS6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

2052056:CTZ24 RS18415
gene id: 2052056:CTZ24_RS18415
uniprot id: A0A6I6AYQ3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

2052056:CTZ24 RS08070
gene id: 2052056:CTZ24_RS08070
uniprot id: A0A6I6AT22
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M20B family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Cleaves the N-terminal amino acid of tripeptides.
messages: Cytoplasm

2052056:CTZ24 RS12050
gene id: 2052056:CTZ24_RS12050
uniprot id: A0A6I6AXM4
names: Similarity
messages: Belongs to the ABC transporter superfamily. Drug exporter-2 (TC 3.A.1.117) family.

2052056:CTZ24 RS11040
gene id: 2052056:CTZ24_RS11040
uniprot id: A0A6I6AXZ1
names: Function
names: Similarity
messages: Belongs to the PurU family.
messages: Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).

2052056:CTZ24 RS12505
gene id: 2052056:CTZ24_RS12505
uniprot id: A0A6I6AVI0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0073 (Hly-III) family.
messages: Membrane

2052056:CTZ24 RS04545
gene id: 2052056:CTZ24_RS04545
uniprot id: A0A6I6ATJ2
names: Similarity
messages: Belongs to the UPF0178 family.

2052056:CTZ24 RS09815
gene id: 2052056:CTZ24_RS09815
uniprot id: A0A6I6AU31
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

2052056:CTZ24 RS10460
gene id: 2052056:CTZ24_RS10460
uniprot id: A0A6I6ATB6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2052056:CTZ24 RS16645
gene id: 2052056:CTZ24_RS16645
uniprot id: A0A6I6B054
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliE family.

2052056:CTZ24 RS05955
gene id: 2052056:CTZ24_RS05955
uniprot id: A0A6I6AQS4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane.

2052056:CTZ24 RS01385
gene id: 2052056:CTZ24_RS01385
uniprot id: A0A6I6AVU6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. Drug exporter-2 (TC 3.A.1.117) family.
messages: Cell inner membrane
messages: Homodimer. Forms a membrane-associated complex with FtsX.
messages: Part of the ABC transporter FtsEX involved in cellular division. Important for assembly or stability of the septal ring.

2052056:CTZ24 RS08595
gene id: 2052056:CTZ24_RS08595
uniprot id: A0A6I6AWS8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in both the arginine and lysine biosynthetic pathways.

2052056:CTZ24 RS01485
gene id: 2052056:CTZ24_RS01485
uniprot id: A0A6I6AT60
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

2052056:CTZ24 RS02475
gene id: 2052056:CTZ24_RS02475
uniprot id: A0A6I6ANQ5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

2052056:CTZ24 RS14460
gene id: 2052056:CTZ24_RS14460
uniprot id: A0A6I6AWQ8
names: Similarity
messages: Belongs to the universal stress protein A family.

2052056:CTZ24 RS01150
gene id: 2052056:CTZ24_RS01150
uniprot id: A0A6I6ANX0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

2052056:CTZ24 RS02775
gene id: 2052056:CTZ24_RS02775
uniprot id: A0A6I6B2D7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptF/LptG family.
messages: Cell inner membrane
messages: Component of the lipopolysaccharide transport and assembly complex. The LptBFG transporter is composed of two ATP-binding proteins (LptB) and two transmembrane proteins (LptF and LptG).
messages: Membrane
messages: Part of the ABC transporter complex LptBFG involved in the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane.

2052056:CTZ24 RS15290
gene id: 2052056:CTZ24_RS15290
uniprot id: A0A6I6AX41
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2052056:CTZ24 RS14215
gene id: 2052056:CTZ24_RS14215
uniprot id: A0A6I6AYW2
names: Similarity
messages: Belongs to the acetyltransferase family. YpeA subfamily.

2052056:CTZ24 RS10680
gene id: 2052056:CTZ24_RS10680
uniprot id: A0A6I6B1Q0
names: Similarity
messages: Belongs to the ABC transporter superfamily. Drug exporter-2 (TC 3.A.1.117) family.

2052056:CTZ24 RS14105
gene id: 2052056:CTZ24_RS14105
uniprot id: A0A6I6AZF1
names: Similarity
messages: Belongs to the ArsC family.

2052056:CTZ24 RS06805
gene id: 2052056:CTZ24_RS06805
uniprot id: A0A6I6ASD4
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS1 family.
messages: Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence.

2052056:CTZ24 RS04270
gene id: 2052056:CTZ24_RS04270
uniprot id: A0A6I6AUB0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm

2052056:CTZ24 RS04910
gene id: 2052056:CTZ24_RS04910
uniprot id: A0A6I6ATR2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. Drug exporter-2 (TC 3.A.1.117) family.
messages: Membrane

2052056:CTZ24 RS06590
gene id: 2052056:CTZ24_RS06590
uniprot id: A0A6I6AS95
names: Similarity
names: Subunit
messages: Belongs to the glutaredoxin family.
messages: Monomer.

2052056:CTZ24 RS03925
gene id: 2052056:CTZ24_RS03925
uniprot id: A0A6I6AX94
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioester dehydratase family. FabZ subfamily.
messages: Cytoplasm
messages: Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.

2052056:CTZ24 RS01960
gene id: 2052056:CTZ24_RS01960
uniprot id: A0A6I6ATE6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

2052056:CTZ24 RS00945
gene id: 2052056:CTZ24_RS00945
uniprot id: A0A6I6AN17
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LysR transcriptional regulatory family.
messages: Cytoplasm

2052056:CTZ24 RS10420
gene id: 2052056:CTZ24_RS10420
uniprot id: A0A6I6B1J2
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

2052056:CTZ24 RS14525
gene id: 2052056:CTZ24_RS14525
uniprot id: A0A6I6AZW7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmB/CycW/HelB family.
messages: Cell inner membrane
messages: Membrane
messages: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.

2052056:CTZ24 RS02120
gene id: 2052056:CTZ24_RS02120
uniprot id: A0A6I6AS30
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sialate:H(+) symporter (SHS) (TC 2.A.1.12) family.
messages: Catalyzes the proton-dependent transport of sialic acid.
messages: Cell inner membrane
messages: Membrane

2052056:CTZ24 RS10590
gene id: 2052056:CTZ24_RS10590
uniprot id: A0A6I6AWU1
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TtcA family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is chelated by three Cys residues, the fourth Fe has a free coordination site that may bind a sulfur atom transferred from the persulfide of IscS.
messages: Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system.
messages: Cytoplasm
messages: Homodimer.
messages: The thiolation reaction likely consists of two steps: a first activation step by ATP to form an adenylated intermediate of the target base of tRNA, and a second nucleophilic substitution step of the sulfur (S) atom supplied by the hydrosulfide attached to the Fe-S cluster.

2052056:CTZ24 RS04135
gene id: 2052056:CTZ24_RS04135
uniprot id: A0A6I6AR06
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

2052056:CTZ24 RS00015
gene id: 2052056:CTZ24_RS00015
uniprot id: A0A6I6AML1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PstS family.
messages: Part of the ABC transporter complex PstSACB involved in phosphate import.
messages: The complex is composed of two ATP-binding proteins (PstB), two transmembrane proteins (PstC and PstA) and a solute-binding protein (PstS).

2052056:CTZ24 RS02625
gene id: 2052056:CTZ24_RS02625
uniprot id: A0A6I6AQK7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

2052056:CTZ24 RS19370
gene id: 2052056:CTZ24_RS19370
uniprot id: A0A6I6AZ62
names: Similarity
messages: Belongs to the MQO family.

2052056:CTZ24 RS12120
gene id: 2052056:CTZ24_RS12120
uniprot id: A0A6I6AYH3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

2052056:CTZ24 RS12015
gene id: 2052056:CTZ24_RS12015
uniprot id: A0A6I6AYF0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Cell inner membrane
messages: Membrane

2052056:CTZ24 RS14905
gene id: 2052056:CTZ24_RS14905
uniprot id: A0A6I6AWW7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 13 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

2052056:CTZ24 RS13175
gene id: 2052056:CTZ24_RS13175
uniprot id: A0A6I6AUM7
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

2052056:CTZ24 RS18495
gene id: 2052056:CTZ24_RS18495
uniprot id: A0A6I6AWY7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

2052056:CTZ24 RS08840
gene id: 2052056:CTZ24_RS08840
uniprot id: A0A6I6ATK8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SufE family.
messages: Cytoplasm
messages: Homodimer. Interacts with SufS.
messages: Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process.

2052056:CTZ24 RS12730
gene id: 2052056:CTZ24_RS12730
uniprot id: A0A6I6AVN1
names: Function
names: Similarity
messages: Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage.
messages: Belongs to the Nudix hydrolase family. RppH subfamily.

2052056:CTZ24 RS16385
gene id: 2052056:CTZ24_RS16385
uniprot id: A0A6I6AVT4
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

2052056:CTZ24 RS00860
gene id: 2052056:CTZ24_RS00860
uniprot id: A0A6I6B5J5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.

2052056:CTZ24 RS04345
gene id: 2052056:CTZ24_RS04345
uniprot id: A0A6I6ATF9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:citrate (SCF) symporter family.
messages: Cell membrane

2052056:CTZ24 RS02545
gene id: 2052056:CTZ24_RS02545
uniprot id: A0A6I6ATE0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

2052056:CTZ24 RS14860
gene id: 2052056:CTZ24_RS14860
uniprot id: A0A6I6B428
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 3 family.
messages: Cell membrane
messages: NDH-1 is composed of 13 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

2052056:CTZ24 RS15020
gene id: 2052056:CTZ24_RS15020
uniprot id: A0A6I6B380
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the RcsB family.
messages: Component of the Rcs signaling system, which controls transcription of numerous genes. RcsB is the response regulator that binds to regulatory DNA regions.
messages: Interacts with RcsD.
messages: Phosphorylated and activated by RcsD.

2052056:CTZ24 RS25915
gene id: 2052056:CTZ24_RS25915
uniprot id: A0A6I6BC95
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane.

2052056:CTZ24 RS02325
gene id: 2052056:CTZ24_RS02325
uniprot id: A0A6I6AS69
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

2052056:CTZ24 RS18210
gene id: 2052056:CTZ24_RS18210
uniprot id: A0A6I6B1I9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. PrmA family.
messages: Cytoplasm
messages: Methylates ribosomal protein L11.

2052056:CTZ24 RS17760
gene id: 2052056:CTZ24_RS17760
uniprot id: A0A6I6B176
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2052056:CTZ24 RS19570
gene id: 2052056:CTZ24_RS19570
uniprot id: A0A6I6AXE9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

2052056:CTZ24 RS20005
gene id: 2052056:CTZ24_RS20005
uniprot id: A0A6I6AZH7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response.
messages: Belongs to the SrkA/RdoA protein kinase family.
messages: Cytoplasm
messages: Monomer.

2052056:CTZ24 RS19685
gene id: 2052056:CTZ24_RS19685
uniprot id: A0A6I6B239
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

2052056:CTZ24 RS17875
gene id: 2052056:CTZ24_RS17875
uniprot id: A0A6I6AWN3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0053 family.
messages: Membrane

2052056:CTZ24 RS17660
gene id: 2052056:CTZ24_RS17660
uniprot id: A0A6I6AWH4
names: Similarity
messages: Belongs to the UxaA family.

2052056:CTZ24 RS08910
gene id: 2052056:CTZ24_RS08910
uniprot id: A0A6I6ASM5
names: Similarity
messages: Belongs to the peptidase C40 family.

2052056:CTZ24 RS12190
gene id: 2052056:CTZ24_RS12190
uniprot id: A0A6I6AU65
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transglycosylase Slt family.
messages: Cell outer membrane
messages: Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and/or cell division.

2052056:CTZ24 RS04735
gene id: 2052056:CTZ24_RS04735
uniprot id: A0A6I6ARD1
names: Caution
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the thiamine-monophosphate kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate.

2052056:CTZ24 RS12540
gene id: 2052056:CTZ24_RS12540
uniprot id: A0A6I6AU03
names: Similarity
messages: Belongs to the RecJ family.

2052056:CTZ24 RS19730
gene id: 2052056:CTZ24_RS19730
uniprot id: A0A6I6AXH8
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. HldD subfamily.
messages: Binds 1 NADP(+) per subunit.
messages: Catalyzes the interconversion between ADP-D-glycero-beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose.
messages: Contains a large N-terminal NADP-binding domain, and a smaller C-terminal substrate-binding domain.
messages: Homopentamer.

2052056:CTZ24 RS10310
gene id: 2052056:CTZ24_RS10310
uniprot id: A0A6I6B1H1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2052056:CTZ24 RS09235
gene id: 2052056:CTZ24_RS09235
uniprot id: A0A6I6B095
names: Similarity
messages: Belongs to the ribulokinase family.

2052056:CTZ24 RS18470
gene id: 2052056:CTZ24_RS18470
uniprot id: A0A6I6B4N6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

2052056:CTZ24 RS18335
gene id: 2052056:CTZ24_RS18335
uniprot id: A0A6I6B126
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

2052056:CTZ24 RS11665
gene id: 2052056:CTZ24_RS11665
uniprot id: A0A6I6B1G9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FtsP family.
messages: Cell division protein that is required for growth during stress conditions. May be involved in protecting or stabilizing the divisomal assembly under conditions of stress.
messages: Periplasm

2052056:CTZ24 RS04840
gene id: 2052056:CTZ24_RS04840
uniprot id: A0A6I6ARF0
names: Similarity
messages: Belongs to the BolA/IbaG family.

2052056:CTZ24 RS16805
gene id: 2052056:CTZ24_RS16805
uniprot id: A0A6I6AW16
names: Similarity
messages: Belongs to the PhoH family.

2052056:CTZ24 RS00535
gene id: 2052056:CTZ24_RS00535
uniprot id: A0A6I6AV74
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

2052056:CTZ24 RS06780
gene id: 2052056:CTZ24_RS06780
uniprot id: A0A6I6ARB6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FNT transporter (TC 2.A.44) family.
messages: Membrane

2052056:CTZ24 RS04970
gene id: 2052056:CTZ24_RS04970
uniprot id: A0A6I6ATS3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

2052056:CTZ24 RS09245
gene id: 2052056:CTZ24_RS09245
uniprot id: A0A6I6AX26
names: Similarity
messages: Belongs to the ABC transporter superfamily. Drug exporter-2 (TC 3.A.1.117) family.

2052056:CTZ24 RS13190
gene id: 2052056:CTZ24_RS13190
uniprot id: A0A6I6B379
names: Subcellular Location Annotation
messages: Cytoplasm

2052056:CTZ24 RS06995
gene id: 2052056:CTZ24_RS06995
uniprot id: A0A6I6AVR9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thioester dehydratase family. FabA subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)-decenoyl-ACP. Can catalyze the dehydratase reaction for beta-hydroxyacyl-ACPs with saturated chain lengths up to 16:0, being most active on intermediate chain length.

2052056:CTZ24 RS14730
gene id: 2052056:CTZ24_RS14730
uniprot id: A0A6I6AV11
names: Subcellular Location Annotation
messages: Membrane

2052056:CTZ24 RS18685
gene id: 2052056:CTZ24_RS18685
uniprot id: A0A6I6AYU8
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

2052056:CTZ24 RS17060
gene id: 2052056:CTZ24_RS17060
uniprot id: A0A6I6B0V6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp).
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2052056:CTZ24 RS03215
gene id: 2052056:CTZ24_RS03215
uniprot id: A0A6I6APA7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 1 subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

2052056:CTZ24 RS14540
gene id: 2052056:CTZ24_RS14540
uniprot id: A0A6I6AVB1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmE/CycJ family.
messages: Cell membrane
messages: Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH.

2052056:CTZ24 RS14245
gene id: 2052056:CTZ24_RS14245
uniprot id: A0A6I6AWD8
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Membrane
messages: Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (CysA), two transmembrane proteins (CysT and CysW) and a solute-binding protein (CysP).

2052056:CTZ24 RS03805
gene id: 2052056:CTZ24_RS03805
uniprot id: A0A6I6AQV5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

2052056:CTZ24 RS26100
gene id: 2052056:CTZ24_RS26100
uniprot id: A0A6I6B1I1
names: Similarity
messages: Belongs to the ABC transporter superfamily. Drug exporter-2 (TC 3.A.1.117) family.

2052056:CTZ24 RS00455
gene id: 2052056:CTZ24_RS00455
uniprot id: A0A6I6APH1
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

2052056:CTZ24 RS11355
gene id: 2052056:CTZ24_RS11355
uniprot id: A0A6I6AUU8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ProQ family.
messages: Cytoplasm
messages: RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities. May regulate ProP activity through an RNA-based, post-transcriptional mechanism.

2052056:CTZ24 RS03855
gene id: 2052056:CTZ24_RS03855
uniprot id: A0A6I6AQW5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family.
messages: Cytoplasm
messages: Homotrimer.

2052056:CTZ24 RS09465
gene id: 2052056:CTZ24_RS09465
uniprot id: A0A6I6AX58
names: Subcellular Location Annotation
messages: Cytoplasm

2052056:CTZ24 RS00575
gene id: 2052056:CTZ24_RS00575
uniprot id: A0A6I6ANN1
names: Similarity
messages: Belongs to the OsmC/Ohr family.

2052056:CTZ24 RS02415
gene id: 2052056:CTZ24_RS02415
uniprot id: A0A6I6ATM9
names: Subcellular Location Annotation
messages: Membrane

2052056:CTZ24 RS01395
gene id: 2052056:CTZ24_RS01395
uniprot id: A0A6I6ARG7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoH subfamily.
messages: Cytoplasm
messages: Interacts with the RNA polymerase core enzyme.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes.

2052056:CTZ24 RS12530
gene id: 2052056:CTZ24_RS12530
uniprot id: A0A6I6AYP4
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerD subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD, in which XerC interacts with XerD via its C-terminal region, XerD interacts with XerC via its C-terminal region and so on.
messages: FtsK may regulate the catalytic switch between XerC and XerD in the heterotetrameric complex during the two steps of the recombination process.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. Binds cooperatively to specific DNA consensus sequences that are separated from XerC binding sites by a short central region, forming the heterotetrameric XerC-XerD complex that recombines DNA substrates. The complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids. In the complex XerD specifically exchanges the bottom DNA strands.

2052056:CTZ24 RS16380
gene id: 2052056:CTZ24_RS16380
uniprot id: A0A6I6AVV1
names: Similarity
messages: Belongs to the leucine-binding protein family.

2052056:CTZ24 RS13375
gene id: 2052056:CTZ24_RS13375
uniprot id: A0A6I6AUE6
names: Similarity
messages: Belongs to the ABC transporter superfamily. Drug exporter-2 (TC 3.A.1.117) family.

2052056:CTZ24 RS01020
gene id: 2052056:CTZ24_RS01020
uniprot id: A0A6I6ANV2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UbiD family.
messages: Binds 1 prenylated FMN (prenyl-FMN) per subunit.
messages: Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis.
messages: Cell membrane
messages: Homohexamer.

2052056:CTZ24 RS01625
gene id: 2052056:CTZ24_RS01625
uniprot id: A0A6I6APK2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

2052056:CTZ24 RS16695
gene id: 2052056:CTZ24_RS16695
uniprot id: A0A6I6B064
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum
messages: Belongs to the FliD family.
messages: Homopentamer.
messages: Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.
messages: Required for the morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.
messages: Secreted

2052056:CTZ24 RS10270
gene id: 2052056:CTZ24_RS10270
uniprot id: A0A6I6AWP0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

2052056:CTZ24 RS02255
gene id: 2052056:CTZ24_RS02255
uniprot id: A0A6I6APX0
names: Similarity
messages: Belongs to the class-II fumarase/aspartase family. Aspartase subfamily.

2052056:CTZ24 RS03905
gene id: 2052056:CTZ24_RS03905
uniprot id: A0A6I6AR57
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

2052056:CTZ24 RS18425
gene id: 2052056:CTZ24_RS18425
uniprot id: A0A6I6B643
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

2052056:CTZ24 RS19285
gene id: 2052056:CTZ24_RS19285
uniprot id: A0A6I6B215
names: Similarity
messages: Belongs to the ABC transporter superfamily. Drug exporter-2 (TC 3.A.1.117) family.

2052056:CTZ24 RS12395
gene id: 2052056:CTZ24_RS12395
uniprot id: A0A6I6AYM2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Cell inner membrane
messages: Homoheptamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mechanosensitive channel that participates in the regulation of osmotic pressure changes within the cell, opening in response to stretch forces in the membrane lipid bilayer, without the need for other proteins. Contributes to normal resistance to hypoosmotic shock. Forms an ion channel of 1.0 nanosiemens conductance with a slight preference for anions.
messages: Membrane

2052056:CTZ24 RS06605
gene id: 2052056:CTZ24_RS06605
uniprot id: A0A6I6AVT8
names: Cofactor
names: Similarity
messages: Belongs to the RimK family.
messages: Binds 2 magnesium or manganese ions per subunit.

2052056:CTZ24 RS06005
gene id: 2052056:CTZ24_RS06005
uniprot id: A0A6I6AQT7
names: Similarity
messages: Belongs to the ABC transporter superfamily. Drug exporter-2 (TC 3.A.1.117) family.

2052056:CTZ24 RS02615
gene id: 2052056:CTZ24_RS02615
uniprot id: A0A6I6ANZ7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

2052056:CTZ24 RS11275
gene id: 2052056:CTZ24_RS11275
uniprot id: A0A6I6AT99
names: Subcellular Location Annotation
messages: Membrane

2052056:CTZ24 RS13275
gene id: 2052056:CTZ24_RS13275
uniprot id: A0A6I6AUA0
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

2052056:CTZ24 RS17550
gene id: 2052056:CTZ24_RS17550
uniprot id: A0A6I6AWF4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

2052056:CTZ24 RS08260
gene id: 2052056:CTZ24_RS08260
uniprot id: A0A6I6AWE9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

2052056:CTZ24 RS07990
gene id: 2052056:CTZ24_RS07990
uniprot id: A0A6I6AVF9
names: Similarity
messages: Belongs to the UPF0227 family.

2052056:CTZ24 RS05790
gene id: 2052056:CTZ24_RS05790
uniprot id: A0A6I6AS29
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ExbB/TolQ family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity. Required, with TolR, for the proton motive force-dependent activation of TolA and for TolA-Pal interaction.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

2052056:CTZ24 RS10210
gene id: 2052056:CTZ24_RS10210
uniprot id: A0A6I6B1E9
names: Similarity
messages: Belongs to the FAD-dependent urate hydroxylase family.

2052056:CTZ24 RS07950
gene id: 2052056:CTZ24_RS07950
uniprot id: A0A6I6ARR7
names: Subcellular Location Annotation
messages: Membrane

2052056:CTZ24 RS18385
gene id: 2052056:CTZ24_RS18385
uniprot id: A0A6I6B141
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

2052056:CTZ24 RS11565
gene id: 2052056:CTZ24_RS11565
uniprot id: A0A6I6AUZ0
names: Similarity
messages: Belongs to the UPF0441 family.

2052056:CTZ24 RS00095
gene id: 2052056:CTZ24_RS00095
uniprot id: A0A6I6AUX4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

2052056:CTZ24 RS19700
gene id: 2052056:CTZ24_RS19700
uniprot id: A0A6I6AZB9
names: Function
names: Similarity
messages: Belongs to the glutaredoxin family.
messages: Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins.

2052056:CTZ24 RS01000
gene id: 2052056:CTZ24_RS01000
uniprot id: A0A6I6AN26
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell membrane
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

2052056:CTZ24 RS17070
gene id: 2052056:CTZ24_RS17070
uniprot id: A0A6I6AW81
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

2052056:CTZ24 RS02420
gene id: 2052056:CTZ24_RS02420
uniprot id: A0A6I6AS88
names: Similarity
messages: Belongs to the ABC transporter superfamily. Drug exporter-2 (TC 3.A.1.117) family.

2052056:CTZ24 RS01610
gene id: 2052056:CTZ24_RS01610
uniprot id: A0A6I6ASX1
names: Similarity
messages: Belongs to the UPF0047 family.

2052056:CTZ24 RS03075
gene id: 2052056:CTZ24_RS03075
uniprot id: A0A6I6AWS6
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

2052056:CTZ24 RS04075
gene id: 2052056:CTZ24_RS04075
uniprot id: A0A6I6AQE5
names: Function
names: Subunit
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease.
messages: The DNA polymerase holoenzyme is a complex that contains 10 different types of subunits. These subunits are organized into 3 functionally essential subassemblies: the pol III core, the beta sliding clamp processivity factor and the clamp-loading complex. The pol III core (subunits alpha,epsilon and theta) contains the polymerase and the 3'-5' exonuclease proofreading activities. The polymerase is tethered to the template via the sliding clamp processivity factor. The clamp-loading complex assembles the beta processivity factor onto the primer template and plays a central role in the organization and communication at the replication fork. This complex contains delta, delta', psi and chi, and copies of either or both of two different DnaX proteins, gamma and tau.

2052056:CTZ24 RS11495
gene id: 2052056:CTZ24_RS11495
uniprot id: A0A6I6B2P4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

2052056:CTZ24 RS09980
gene id: 2052056:CTZ24_RS09980
uniprot id: A0A6I6AT47
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. Drug exporter-2 (TC 3.A.1.117) family.
messages: Cell inner membrane
messages: Membrane

2052056:CTZ24 RS03450
gene id: 2052056:CTZ24_RS03450
uniprot id: A0A6I6AWZ9
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2052056:CTZ24 RS04855
gene id: 2052056:CTZ24_RS04855
uniprot id: A0A6I6AUX8
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

2052056:CTZ24 RS15005
gene id: 2052056:CTZ24_RS15005
uniprot id: A0A6I6AX00
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily. UbiG/COQ3 family.
messages: O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway.

2052056:CTZ24 RS00750
gene id: 2052056:CTZ24_RS00750
uniprot id: A0A6I6ASM7
names: Similarity
messages: Belongs to the thioredoxin family.

2052056:CTZ24 RS10620
gene id: 2052056:CTZ24_RS10620
uniprot id: A0A6I6AUG0
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the peroxiredoxin family. Tpx subfamily.
messages: Homodimer.
messages: The active site is a conserved redox-active cysteine residue, the peroxidatic cysteine (C(P)), which makes the nucleophilic attack on the peroxide substrate. The peroxide oxidizes the C(P)-SH to cysteine sulfenic acid (C(P)-SOH), which then reacts with another cysteine residue, the resolving cysteine (C(R)), to form a disulfide bridge. The disulfide is subsequently reduced by an appropriate electron donor to complete the catalytic cycle. In this atypical 2-Cys peroxiredoxin, C(R) is present in the same subunit to form an intramolecular disulfide. The disulfide is subsequently reduced by thioredoxin.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

2052056:CTZ24 RS25130
gene id: 2052056:CTZ24_RS25130
uniprot id: A0A6I6B1D3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone-like protein H-NS family.
messages: nucleoid

2052056:CTZ24 RS14715
gene id: 2052056:CTZ24_RS14715
uniprot id: A0A6I6AZN6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccD/PCCB family.
messages: Binds 1 zinc ion per subunit.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

2052056:CTZ24 RS02680
gene id: 2052056:CTZ24_RS02680
uniprot id: A0A6I6AQM1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase U32 family. UbiU subfamily.
messages: Forms an heterodimer with UbiV.
messages: Required for O(2)-independent ubiquinone (coenzyme Q) biosynthesis. Together with UbiV, is essential for the C6-hydroxylation reaction in the oxygen-independent ubiquinone biosynthesis pathway.

2052056:CTZ24 RS11115
gene id: 2052056:CTZ24_RS11115
uniprot id: A0A6I6AT67
names: Function
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
messages: Catalyzes the oxidative phosphorylation of glyceraldehyde 3-phosphate (G3P) to 1,3-bisphosphoglycerate (BPG) using the cofactor NAD. The first reaction step involves the formation of a hemiacetal intermediate between G3P and a cysteine residue, and this hemiacetal intermediate is then oxidized to a thioester, with concomitant reduction of NAD to NADH. The reduced NADH is then exchanged with the second NAD, and the thioester is attacked by a nucleophilic inorganic phosphate to produce BPG.

2052056:CTZ24 RS20050
gene id: 2052056:CTZ24_RS20050
uniprot id: A0A6I6AXN2
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

2052056:CTZ24 RS03070
gene id: 2052056:CTZ24_RS03070
uniprot id: A0A6I6AQB5
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

2052056:CTZ24 RS18680
gene id: 2052056:CTZ24_RS18680
uniprot id: A0A6I6AXB7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

2052056:CTZ24 RS08925
gene id: 2052056:CTZ24_RS08925
uniprot id: A0A6I6B0M5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the glyoxalase I family.
messages: Binds 1 nickel ion per subunit.
messages: Binds 1 zinc ion per subunit. In the homodimer, two zinc ions are bound between subunits.
messages: Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione.

2052056:CTZ24 RS04365
gene id: 2052056:CTZ24_RS04365
uniprot id: A0A6I6ARE3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HpcH/HpaI aldolase family. Citrate lyase beta subunit subfamily.
messages: Cytoplasm
messages: Oligomer with a subunit composition of (alpha,beta,gamma)6.
messages: Represents a citryl-ACP lyase.

2052056:CTZ24 RS09215
gene id: 2052056:CTZ24_RS09215
uniprot id: A0A6I6AWU8
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

2052056:CTZ24 RS11625
gene id: 2052056:CTZ24_RS11625
uniprot id: A0A6I6AY92
names: Cofactor
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.

2052056:CTZ24 RS05490
gene id: 2052056:CTZ24_RS05490
uniprot id: A0A6I6AUZ3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptE lipoprotein family.
messages: Cell outer membrane
messages: Component of the lipopolysaccharide transport and assembly complex. Interacts with LptD.
messages: Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane.

2052056:CTZ24 RS11935
gene id: 2052056:CTZ24_RS11935
uniprot id: A0A6I6B2G3
names: Function
names: Similarity
messages: Belongs to the mannonate dehydratase family.
messages: Catalyzes the dehydration of D-mannonate.

2052056:CTZ24 RS04760
gene id: 2052056:CTZ24_RS04760
uniprot id: A0A6I6AQ16
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

2052056:CTZ24 RS05055
gene id: 2052056:CTZ24_RS05055
uniprot id: A0A6I6ARI5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2052056:CTZ24 RS06030
gene id: 2052056:CTZ24_RS06030
uniprot id: A0A6I6ARY7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MoaC family.
messages: Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
messages: Homohexamer; trimer of dimers.

2052056:CTZ24 RS20130
gene id: 2052056:CTZ24_RS20130
uniprot id: A0A6I6AZK5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase A chain family.
messages: Cell membrane
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

2052056:CTZ24 RS06425
gene id: 2052056:CTZ24_RS06425
uniprot id: A0A6I6AVF1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. Drug exporter-2 (TC 3.A.1.117) family.
messages: Cell inner membrane
messages: Membrane

2052056:CTZ24 RS15375
gene id: 2052056:CTZ24_RS15375
uniprot id: A0A6I6AVD1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

2052056:CTZ24 RS03950
gene id: 2052056:CTZ24_RS03950
uniprot id: A0A6I6APM6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccA family.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

2052056:CTZ24 RS14240
gene id: 2052056:CTZ24_RS14240
uniprot id: A0A6I6AV69
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the ABC transporter complex (TC 3.A.1.6.1) involved in sulfate/thiosulfate import.
messages: Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (CysA), two transmembrane proteins (CysT and CysW) and a solute-binding protein (CysP).

2052056:CTZ24 RS12525
gene id: 2052056:CTZ24_RS12525
uniprot id: A0A6I6B2U3
names: Function
names: Similarity
messages: Belongs to the flavodoxin family.
messages: Low-potential electron donor to a number of redox enzymes.

2052056:CTZ24 RS08485
gene id: 2052056:CTZ24_RS08485
uniprot id: A0A6I6AZV8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FlhC family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Functions in complex with FlhD as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region. Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes. Also regulates genes whose products function in a variety of physiological pathways.
messages: Heterohexamer composed of two FlhC and four FlhD subunits. Each FlhC binds a FlhD dimer, forming a heterotrimer, and a hexamer assembles by dimerization of two heterotrimers.

2052056:CTZ24 RS02405
gene id: 2052056:CTZ24_RS02405
uniprot id: A0A6I6AWE6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the KdsC family.
messages: Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate.
messages: Homotetramer.

2052056:CTZ24 RS19565
gene id: 2052056:CTZ24_RS19565
uniprot id: A0A6I6AXI1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MetJ family.
messages: Cytoplasm
messages: Does not bind DNA by a helix-turn-helix motif.
messages: Homodimer.
messages: This regulatory protein, when combined with SAM (S-adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis.

2052056:CTZ24 RS05940
gene id: 2052056:CTZ24_RS05940
uniprot id: A0A6I6AYT7
names: Similarity
messages: Belongs to the ModE family.

2052056:CTZ24 RS03715
gene id: 2052056:CTZ24_RS03715
uniprot id: A0A6I6AXC7
names: Similarity
messages: Belongs to the ABC transporter superfamily. Drug exporter-2 (TC 3.A.1.117) family.

2052056:CTZ24 RS12900
gene id: 2052056:CTZ24_RS12900
uniprot id: A0A6I6B290
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family. GlucD subfamily.

2052056:CTZ24 RS20000
gene id: 2052056:CTZ24_RS20000
uniprot id: A0A6I6B286
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbA subfamily.
messages: Periplasm

2052056:CTZ24 RS02490
gene id: 2052056:CTZ24_RS02490
uniprot id: A0A6I6AQI9
names: Cofactor
messages: Binds 1 phosphopantetheine covalently.

2052056:CTZ24 RS14635
gene id: 2052056:CTZ24_RS14635
uniprot id: A0A6I6AZP9
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

2052056:CTZ24 RS13915
gene id: 2052056:CTZ24_RS13915
uniprot id: A0A6I6AV05
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

2052056:CTZ24 RS17985
gene id: 2052056:CTZ24_RS17985
uniprot id: A0A6I6AWQ2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the band 7/mec-2 family. HflK subfamily.
messages: HflC and HflK could encode or regulate a protease.
messages: HflC and HflK may interact to form a multimeric complex.
messages: Membrane

2052056:CTZ24 RS01070
gene id: 2052056:CTZ24_RS01070
uniprot id: A0A6I6APS8
names: Function
names: Similarity
messages: Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon.
messages: Belongs to the biotin--protein ligase family.

2052056:CTZ24 RS16700
gene id: 2052056:CTZ24_RS16700
uniprot id: A0A6I6AW12
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

2052056:CTZ24 RS19785
gene id: 2052056:CTZ24_RS19785
uniprot id: A0A6I6B261
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

2052056:CTZ24 RS14005
gene id: 2052056:CTZ24_RS14005
uniprot id: A0A6I6B2R2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

2052056:CTZ24 RS03910
gene id: 2052056:CTZ24_RS03910
uniprot id: A0A6I6AQC4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamA family.
messages: Cell outer membrane
messages: Part of the Bam complex, which is composed of the outer membrane protein BamA, and four lipoproteins BamB, BamC, BamD and BamE.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. Constitutes, with BamD, the core component of the assembly machinery.

2052056:CTZ24 RS21390
gene id: 2052056:CTZ24_RS21390
uniprot id: A0A6I6B0S1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the hok/gef family.
messages: Cell inner membrane

2052056:CTZ24 RS02450
gene id: 2052056:CTZ24_RS02450
uniprot id: A0A6I6AQ19
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm

2052056:CTZ24 RS03390
gene id: 2052056:CTZ24_RS03390
uniprot id: A0A6I6AQG5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 1 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

2052056:CTZ24 RS04860
gene id: 2052056:CTZ24_RS04860
uniprot id: A0A6I6ATQ2
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

2052056:CTZ24 RS02395
gene id: 2052056:CTZ24_RS02395
uniprot id: A0A6I6APM5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptA family.
messages: Component of the lipopolysaccharide transport and assembly complex.
messages: Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm.
messages: Periplasm

2052056:CTZ24 RS17125
gene id: 2052056:CTZ24_RS17125
uniprot id: A0A6I6B0Z5
names: Similarity
messages: Belongs to the pyruvate kinase family.

2052056:CTZ24 RS07190
gene id: 2052056:CTZ24_RS07190
uniprot id: A0A6I6AW41
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

2052056:CTZ24 RS19800
gene id: 2052056:CTZ24_RS19800
uniprot id: A0A6I6AZD6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

2052056:CTZ24 RS04250
gene id: 2052056:CTZ24_RS04250
uniprot id: A0A6I6AUK6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. XGPT subfamily.
messages: Cell membrane
messages: Homotetramer.
messages: Purine salvage pathway enzyme that catalyzes the transfer of the ribosyl-5-phosphate group from 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to the N9 position of the 6-oxopurines guanine and xanthine to form the corresponding ribonucleotides GMP (guanosine 5'-monophosphate) and XMP (xanthosine 5'-monophosphate), with the release of PPi. To a lesser extent, also acts on hypoxanthine.

2052056:CTZ24 RS16610
gene id: 2052056:CTZ24_RS16610
uniprot id: A0A6I6B0Q3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliL family.
messages: Cell inner membrane
messages: Controls the rotational direction of flagella during chemotaxis.
messages: Membrane

2052056:CTZ24 RS11800
gene id: 2052056:CTZ24_RS11800
uniprot id: A0A6I6AV62
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferritin family. Prokaryotic subfamily.
messages: Cytoplasm
messages: Iron-storage protein.

2052056:CTZ24 RS13600
gene id: 2052056:CTZ24_RS13600
uniprot id: A0A6I6AUG5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DEAD box helicase family. SrmB subfamily.
messages: Cytoplasm
messages: DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit at low temperature. Exhibits RNA-stimulated ATP hydrolysis and RNA unwinding activity.
messages: Interacts with the 50S ribosomal subunit.

2052056:CTZ24 RS13910
gene id: 2052056:CTZ24_RS13910
uniprot id: A0A6I6AWF3
names: Activity Regulation
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

2052056:CTZ24 RS17095
gene id: 2052056:CTZ24_RS17095
uniprot id: A0A6I6AY32
names: Similarity
messages: Belongs to the ABC transporter superfamily. Drug exporter-2 (TC 3.A.1.117) family.

2052056:CTZ24 RS14815
gene id: 2052056:CTZ24_RS14815
uniprot id: A0A6I6AZR3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ABC transporter superfamily. Drug exporter-2 (TC 3.A.1.117) family.
messages: Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family.
messages: Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system.
messages: The complex is composed of two ATP-binding proteins (PotA), two transmembrane proteins (PotB and PotC) and a solute-binding protein (PotD).

2052056:CTZ24 RS13195
gene id: 2052056:CTZ24_RS13195
uniprot id: A0A6I6AYZ8
names: Function
names: Subcellular Location Annotation
messages: Catalyzes the Claisen rearrangement of chorismate to prephenate and the decarboxylation/dehydration of prephenate to phenylpyruvate.
messages: Cytoplasm

2052056:CTZ24 RS13215
gene id: 2052056:CTZ24_RS13215
uniprot id: A0A6I6AUB8
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

2052056:CTZ24 RS16310
gene id: 2052056:CTZ24_RS16310
uniprot id: A0A6I6B4V7
names: Similarity
messages: Belongs to the ABC transporter superfamily. Drug exporter-2 (TC 3.A.1.117) family.

2052056:CTZ24 RS19890
gene id: 2052056:CTZ24_RS19890
uniprot id: A0A6I6B274
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

2052056:CTZ24 RS14750
gene id: 2052056:CTZ24_RS14750
uniprot id: A0A6I6AWM3
names: Caution
names: Function
names: Similarity
messages: Belongs to the UbiX/PAD1 family.
messages: Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2052056:CTZ24 RS14960
gene id: 2052056:CTZ24_RS14960
uniprot id: A0A6I6B370
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.

2052056:CTZ24 RS04845
gene id: 2052056:CTZ24_RS04845
uniprot id: A0A6I6AXT0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

2052056:CTZ24 RS00130
gene id: 2052056:CTZ24_RS00130
uniprot id: A0A6I6ANG1
names: Subcellular Location Annotation
messages: Membrane

2052056:CTZ24 RS05510
gene id: 2052056:CTZ24_RS05510
uniprot id: A0A6I6AY63
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

2052056:CTZ24 RS18345
gene id: 2052056:CTZ24_RS18345
uniprot id: A0A6I6AWU3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

2052056:CTZ24 RS18235
gene id: 2052056:CTZ24_RS18235
uniprot id: A0A6I6AYN4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

2052056:CTZ24 RS01710
gene id: 2052056:CTZ24_RS01710
uniprot id: A0A6I6ANE1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2052056:CTZ24 RS12150
gene id: 2052056:CTZ24_RS12150
uniprot id: A0A6I6B1P6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

2052056:CTZ24 RS04255
gene id: 2052056:CTZ24_RS04255
uniprot id: A0A6I6ATD1
names: Function
names: Similarity
messages: Belongs to the FrsA family.
messages: Catalyzes the hydrolysis of esters.

2052056:CTZ24 RS23500
gene id: 2052056:CTZ24_RS23500
uniprot id: A0A6I6B0D1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. Drug exporter-2 (TC 3.A.1.117) family.
messages: Cell inner membrane
messages: Membrane

2052056:CTZ24 RS13635
gene id: 2052056:CTZ24_RS13635
uniprot id: A0A6I6AZ74
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

2052056:CTZ24 RS05850
gene id: 2052056:CTZ24_RS05850
uniprot id: A0A6I6AV53
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nicotinamide ribonucleoside (NR) uptake permease (TC 4.B.1) family.
messages: Membrane
messages: Required for nicotinamide riboside transport across the inner membrane.

2052056:CTZ24 RS20140
gene id: 2052056:CTZ24_RS20140
uniprot id: A0A6I6B740
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0). The b'-subunit is a diverged and duplicated form of b found in plants and photosynthetic bacteria.
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

2052056:CTZ24 RS11000
gene id: 2052056:CTZ24_RS11000
uniprot id: A0A6I6AT53
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidine kinase family.
messages: Cytoplasm
messages: Homotetramer.

2052056:CTZ24 RS00325
gene id: 2052056:CTZ24_RS00325
uniprot id: A0A6I6AML7
names: Similarity
messages: Belongs to the ABC transporter superfamily. Drug exporter-2 (TC 3.A.1.117) family.

2052056:CTZ24 RS17080
gene id: 2052056:CTZ24_RS17080
uniprot id: A0A6I6B0Y6
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvA family.
messages: Cytoplasm
messages: Has three domains with a flexible linker between the domains II and III and assumes an 'L' shape. Domain III is highly mobile and contacts RuvB.
messages: Homotetramer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

2052056:CTZ24 RS12670
gene id: 2052056:CTZ24_RS12670
uniprot id: A0A6I6AUE3
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

2052056:CTZ24 RS02745
gene id: 2052056:CTZ24_RS02745
uniprot id: A0A6I6AWM1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RraB family.
messages: Cytoplasm
messages: Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome.
messages: Interacts with the C-terminal region of Rne.

2052056:CTZ24 RS07845
gene id: 2052056:CTZ24_RS07845
uniprot id: A0A6I6ARS6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
messages: Bacterial flagellum basal body
messages: Belongs to the FlgH family.
messages: Cell outer membrane
messages: Membrane
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod.

2052056:CTZ24 RS04210
gene id: 2052056:CTZ24_RS04210
uniprot id: A0A6I6APK8
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SIS family. GmhA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate.
messages: Cytoplasm
messages: Homotetramer.
messages: The reaction produces a racemic mixture of D-glycero-alpha-D-manno-heptose 7-phosphate and D-glycero-beta-D-manno-heptose 7-phosphate.

2052056:CTZ24 RS25020
gene id: 2052056:CTZ24_RS25020
uniprot id: A0A6I6B164
names: Similarity
messages: Belongs to the NifZ family.

2052056:CTZ24 RS12840
gene id: 2052056:CTZ24_RS12840
uniprot id: A0A6I6AUH2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0382 family.
messages: Membrane

2052056:CTZ24 RS08880
gene id: 2052056:CTZ24_RS08880
uniprot id: A0A6I6AWW6
names: Function
messages: Catalyzes the dismutation of two molecules of 6,7-dimethyl-8-ribityllumazine, resulting in the formation of riboflavin and 5-amino-6-(D-ribitylamino)uracil.

2052056:CTZ24 RS16690
gene id: 2052056:CTZ24_RS16690
uniprot id: A0A6I6B0P1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliS family.
messages: cytosol

2052056:CTZ24 RS06220
gene id: 2052056:CTZ24_RS06220
uniprot id: A0A6I6ASA2
names: Subcellular Location Annotation
messages: Membrane

2052056:CTZ24 RS26620
gene id: 2052056:CTZ24_RS26620
uniprot id: A0A6I6B9U0
names: Similarity
messages: Belongs to the SorC transcriptional regulatory family.

2052056:CTZ24 RS19060
gene id: 2052056:CTZ24_RS19060
uniprot id: A0A6I6AZ07
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal stress protein A family.
messages: Cytoplasm

2052056:CTZ24 RS15315
gene id: 2052056:CTZ24_RS15315
uniprot id: A0A6I6B011
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial solute-binding protein 2 family.
messages: Periplasm
messages: The ABC transporter complex is composed of one ATP-binding protein (MglA), two transmembrane proteins (MglC) and a solute-binding protein (MglB).

2052056:CTZ24 RS06955
gene id: 2052056:CTZ24_RS06955
uniprot id: A0A6I6ASG6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ZapC family.
messages: Contributes to the efficiency of the cell division process by stabilizing the polymeric form of the cell division protein FtsZ. Acts by promoting interactions between FtsZ protofilaments and suppressing the GTPase activity of FtsZ.
messages: Cytoplasm
messages: Interacts directly with FtsZ.

2052056:CTZ24 RS02315
gene id: 2052056:CTZ24_RS02315
uniprot id: A0A6I6AWF5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZapG family.
messages: Cell inner membrane
messages: Membrane

2052056:CTZ24 RS18640
gene id: 2052056:CTZ24_RS18640
uniprot id: A0A6I6B4S4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. TsgA family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

2052056:CTZ24 RS01915
gene id: 2052056:CTZ24_RS01915
uniprot id: A0A6I6AY26
names: Similarity
messages: Belongs to the bacterial PQQ dehydrogenase family.

2052056:CTZ24 RS07175
gene id: 2052056:CTZ24_RS07175
uniprot id: A0A6I6ASK9
names: Similarity
messages: Belongs to the autoinducer synthase family.

2052056:CTZ24 RS02550
gene id: 2052056:CTZ24_RS02550
uniprot id: A0A6I6AQJ9
names: Subcellular Location Annotation
messages: Cell inner membrane

2052056:CTZ24 RS08320
gene id: 2052056:CTZ24_RS08320
uniprot id: A0A6I6ASD5
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

2052056:CTZ24 RS09160
gene id: 2052056:CTZ24_RS09160
uniprot id: A0A6I6ASA1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

2052056:CTZ24 RS03730
gene id: 2052056:CTZ24_RS03730
uniprot id: A0A6I6APC6
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanD family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
messages: Cytoplasm
messages: Heterooctamer of four alpha and four beta subunits.
messages: Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus.

2052056:CTZ24 RS14255
gene id: 2052056:CTZ24_RS14255
uniprot id: A0A6I6B3S7
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

2052056:CTZ24 RS16885
gene id: 2052056:CTZ24_RS16885
uniprot id: A0A6I6B402
names: Similarity
messages: Belongs to the UPF0162 family.

2052056:CTZ24 RS11515
gene id: 2052056:CTZ24_RS11515
uniprot id: A0A6I6AUY1
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane
messages: Membrane

2052056:CTZ24 RS19900
gene id: 2052056:CTZ24_RS19900
uniprot id: A0A6I6AXW9
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

2052056:CTZ24 RS18420
gene id: 2052056:CTZ24_RS18420
uniprot id: A0A6I6B4M6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

2052056:CTZ24 RS10305
gene id: 2052056:CTZ24_RS10305
uniprot id: A0A6I6B0T5
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

2052056:CTZ24 RS18475
gene id: 2052056:CTZ24_RS18475
uniprot id: A0A6I6B653
names: Function
names: Similarity
messages: Belongs to the bacterioferritin family.
messages: Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex.

2052056:CTZ24 RS19960
gene id: 2052056:CTZ24_RS19960
uniprot id: A0A6I6AZG8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glutamine synthetase family.
messages: Catalyzes the ATP-dependent biosynthesis of glutamine from glutamate and ammonia.
messages: Cytoplasm
messages: Oligomer of 12 subunits arranged in the form of two hexagons.

2052056:CTZ24 RS16635
gene id: 2052056:CTZ24_RS16635
uniprot id: A0A6I6B523
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliG family.
messages: Cell inner membrane
messages: FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
messages: Membrane

2052056:CTZ24 RS10525
gene id: 2052056:CTZ24_RS10525
uniprot id: A0A6I6B1L7
names: Similarity
messages: Belongs to the peptidase S1B family.

2052056:CTZ24 RS04975
gene id: 2052056:CTZ24_RS04975
uniprot id: A0A6I6AQ56
names: Similarity
messages: Belongs to the bacterial solute-binding protein 9 family.

2052056:CTZ24 RS05590
gene id: 2052056:CTZ24_RS05590
uniprot id: A0A6I6AR10
names: Similarity
messages: Belongs to the asparagine synthetase family.

2052056:CTZ24 RS01940
gene id: 2052056:CTZ24_RS01940
uniprot id: A0A6I6APD6
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

2052056:CTZ24 RS05390
gene id: 2052056:CTZ24_RS05390
uniprot id: A0A6I6AQZ0
names: Subcellular Location Annotation
messages: Cytoplasm

2052056:CTZ24 RS09240
gene id: 2052056:CTZ24_RS09240
uniprot id: A0A6I6B0T8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 2 family.
messages: Periplasm

2052056:CTZ24 RS11295
gene id: 2052056:CTZ24_RS11295
uniprot id: A0A6I6ATR3
names: Subcellular Location Annotation
messages: Membrane

2052056:CTZ24 RS02470
gene id: 2052056:CTZ24_RS02470
uniprot id: A0A6I6ASA4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

2052056:CTZ24 RS14785
gene id: 2052056:CTZ24_RS14785
uniprot id: A0A6I6AZS2
names: Similarity
messages: Belongs to the Nudix hydrolase family.

2052056:CTZ24 RS23540
gene id: 2052056:CTZ24_RS23540
uniprot id: A0A6I6B227
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Gram-negative porin family.
messages: Cell outer membrane
messages: Homotrimer.
messages: Membrane

2052056:CTZ24 RS07805
gene id: 2052056:CTZ24_RS07805
uniprot id: A0A6I6AW53
names: Function
names: Similarity
messages: Belongs to the FlgM family.
messages: Responsible for the coupling of flagellin expression to flagellar assembly by preventing expression of the flagellin genes when a component of the middle class of proteins is defective. It negatively regulates flagellar genes by inhibiting the activity of FliA by directly binding to FliA.

2052056:CTZ24 RS08785
gene id: 2052056:CTZ24_RS08785
uniprot id: A0A6I6ATJ9
names: Function
names: Similarity
messages: Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PSRP subfamily.
messages: Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation/dephosphorylation.

2052056:CTZ24 RS12285
gene id: 2052056:CTZ24_RS12285
uniprot id: A0A6I6AVD8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

2052056:CTZ24 RS01730
gene id: 2052056:CTZ24_RS01730
uniprot id: A0A6I6APM3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Cell inner membrane
messages: Membrane
messages: Transports acetate.

2052056:CTZ24 RS06890
gene id: 2052056:CTZ24_RS06890
uniprot id: A0A6I6AVQ3
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.

2052056:CTZ24 RS23285
gene id: 2052056:CTZ24_RS23285
uniprot id: A0A6I6B2J3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2052056:CTZ24 RS03885
gene id: 2052056:CTZ24_RS03885
uniprot id: A0A6I6AXY5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

2052056:CTZ24 RS19075
gene id: 2052056:CTZ24_RS19075
uniprot id: A0A6I6B1X7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RlmJ family.
messages: Monomer.
messages: Specifically methylates the adenine in position 2030 of 23S rRNA.

2052056:CTZ24 RS12945
gene id: 2052056:CTZ24_RS12945
uniprot id: A0A6I6AVR4
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Component of the RNA degradosome, which is a multiprotein complex involved in RNA processing and mRNA degradation.
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

2052056:CTZ24 RS13750
gene id: 2052056:CTZ24_RS13750
uniprot id: A0A6I6AUJ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

2052056:CTZ24 RS14530
gene id: 2052056:CTZ24_RS14530
uniprot id: A0A6I6AYC3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmC/CycZ/HelC family.
messages: Cell inner membrane
messages: Membrane
messages: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.

2052056:CTZ24 RS19460
gene id: 2052056:CTZ24_RS19460
uniprot id: A0A6I6B206
names: Similarity
messages: Belongs to the UPF0438 family.

2052056:CTZ24 RS12595
gene id: 2052056:CTZ24_RS12595
uniprot id: A0A6I6AU13
names: Subcellular Location Annotation
messages: Membrane

2052056:CTZ24 RS02695
gene id: 2052056:CTZ24_RS02695
uniprot id: A0A6I6AWL1
names: Similarity
messages: Belongs to the UPF0213 family.

2052056:CTZ24 RS10995
gene id: 2052056:CTZ24_RS10995
uniprot id: A0A6I6AX14
names: Similarity
messages: In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.
messages: In the N-terminal section; belongs to the aldehyde dehydrogenase family.

2052056:CTZ24 RS14770
gene id: 2052056:CTZ24_RS14770
uniprot id: A0A6I6AZ66
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. Drug exporter-2 (TC 3.A.1.117) family.
messages: Cell inner membrane
messages: Membrane

2052056:CTZ24 RS10375
gene id: 2052056:CTZ24_RS10375
uniprot id: A0A6I6ASW2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L-rhamnose transporter (TC 2.A.7.6) family.
messages: Cell membrane
messages: Uptake of L-rhamnose across the cytoplasmic membrane with the concomitant transport of protons into the cell (symport system).

2052056:CTZ24 RS18465
gene id: 2052056:CTZ24_RS18465
uniprot id: A0A6I6AYR3
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: Methylated by PrmB.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

2052056:CTZ24 RS25255
gene id: 2052056:CTZ24_RS25255
uniprot id: A0A6I6B5X9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

2052056:CTZ24 RS05995
gene id: 2052056:CTZ24_RS05995
uniprot id: A0A6I6AVJ3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dethiobiotin synthetase family.
messages: Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2052056:CTZ24 RS05140
gene id: 2052056:CTZ24_RS05140
uniprot id: A0A6I6AQ90
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

2052056:CTZ24 RS10315
gene id: 2052056:CTZ24_RS10315
uniprot id: A0A6I6AXK8
names: Subcellular Location Annotation
messages: Membrane

2052056:CTZ24 RS17810
gene id: 2052056:CTZ24_RS17810
uniprot id: A0A6I6B181
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the cytochrome b562 family.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per molecule.
messages: Electron-transport protein of unknown function.

2052056:CTZ24 RS02565
gene id: 2052056:CTZ24_RS02565
uniprot id: A0A6I6AQ40
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

2052056:CTZ24 RS15300
gene id: 2052056:CTZ24_RS15300
uniprot id: A0A6I6AX28
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family.
messages: Homopolymer.
messages: Toroid-shaped homodecamer, composed of two pentamers of five dimers.

2052056:CTZ24 RS04865
gene id: 2052056:CTZ24_RS04865
uniprot id: A0A6I6AQ34
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

2052056:CTZ24 RS02290
gene id: 2052056:CTZ24_RS02290
uniprot id: A0A6I6AT90
names: Similarity
messages: Belongs to the EcnA/EcnB lipoprotein family.

2052056:CTZ24 RS04655
gene id: 2052056:CTZ24_RS04655
uniprot id: A0A6I6B2E4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the branched chain amino acid transporter family.
messages: Cell inner membrane
messages: Component of the transport system for branched-chain amino acids.
messages: Membrane

2052056:CTZ24 RS02070
gene id: 2052056:CTZ24_RS02070
uniprot id: A0A6I6AS20
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

2052056:CTZ24 RS09220
gene id: 2052056:CTZ24_RS09220
uniprot id: A0A6I6ATS0
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

2052056:CTZ24 RS15285
gene id: 2052056:CTZ24_RS15285
uniprot id: A0A6I6B016
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.

2052056:CTZ24 RS10800
gene id: 2052056:CTZ24_RS10800
uniprot id: A0A6I6AXR7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2052056:CTZ24 RS21855
gene id: 2052056:CTZ24_RS21855
uniprot id: A0A6I6B426
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nlpA lipoprotein family.
messages: Membrane

2052056:CTZ24 RS08900
gene id: 2052056:CTZ24_RS08900
uniprot id: A0A6I6AWP4
names: Domain
names: Function
names: Subunit
messages: Consists of two structural and functional domains: an N-terminal DNA-binding domain, approximately the first 60 residues, and a larger C-terminal domain, approximately 280 residues, which imparts the function of corepressor binding and oligomerization.
messages: Homodimer.
messages: Is the main repressor of the genes involved in the de novo synthesis of purine nucleotides, regulating purB, purC, purEK, purF, purHD, purL, purMN and guaBA expression. PurR is allosterically activated to bind its cognate DNA by binding the purine corepressors, hypoxanthine or guanine, thereby effecting transcription repression.

2052056:CTZ24 RS15460
gene id: 2052056:CTZ24_RS15460
uniprot id: A0A6I6AZJ6
names: Subcellular Location Annotation
messages: Cell inner membrane

2052056:CTZ24 RS03310
gene id: 2052056:CTZ24_RS03310
uniprot id: A0A6I6AP46
names: Function
names: Similarity
messages: Belongs to the Ap4A hydrolase family.
messages: Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP.

2052056:CTZ24 RS10875
gene id: 2052056:CTZ24_RS10875
uniprot id: A0A6I6B1T5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

2052056:CTZ24 RS03605
gene id: 2052056:CTZ24_RS03605
uniprot id: A0A6I6B772
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

2052056:CTZ24 RS01145
gene id: 2052056:CTZ24_RS01145
uniprot id: A0A6I6APU3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

2052056:CTZ24 RS03305
gene id: 2052056:CTZ24_RS03305
uniprot id: A0A6I6ASP9
names: Function
names: Similarity
messages: Belongs to the dihydrofolate reductase family.
messages: Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.

2052056:CTZ24 RS17715
gene id: 2052056:CTZ24_RS17715
uniprot id: A0A6I6AZZ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DoxX family.
messages: Membrane

2052056:CTZ24 RS05650
gene id: 2052056:CTZ24_RS05650
uniprot id: A0A6I6ARS4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SeqA family.
messages: Cytoplasm
messages: Homodimer. Polymerizes to form helical filaments.
messages: Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re-initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated.

2052056:CTZ24 RS13435
gene id: 2052056:CTZ24_RS13435
uniprot id: A0A6I6AZ60
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

2052056:CTZ24 RS08915
gene id: 2052056:CTZ24_RS08915
uniprot id: A0A6I6ATH8
names: Function
names: Similarity
messages: Belongs to the glutaredoxin family. Monothiol subfamily.
messages: Monothiol glutaredoxin involved in the biogenesis of iron-sulfur clusters.

2052056:CTZ24 RS16835
gene id: 2052056:CTZ24_RS16835
uniprot id: A0A6I6B3Z4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

2052056:CTZ24 RS17995
gene id: 2052056:CTZ24_RS17995
uniprot id: A0A6I6B1E5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Hfq family.
messages: Homohexamer.
messages: RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs.

2052056:CTZ24 RS06125
gene id: 2052056:CTZ24_RS06125
uniprot id: A0A6I6ARB5
names: Subcellular Location Annotation
messages: Membrane

2052056:CTZ24 RS01210
gene id: 2052056:CTZ24_RS01210
uniprot id: A0A6I6AVR8
names: Similarity
messages: Belongs to the GARS family.

2052056:CTZ24 RS04555
gene id: 2052056:CTZ24_RS04555
uniprot id: A0A6I6APY7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

2052056:CTZ24 RS04695
gene id: 2052056:CTZ24_RS04695
uniprot id: A0A6I6AY29
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YajC family.
messages: Cell inner membrane
messages: Membrane

2052056:CTZ24 RS00150
gene id: 2052056:CTZ24_RS00150
uniprot id: A0A6I6AUY4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associates with aggregated proteins, together with IbpB, to stabilize and protect them from irreversible denaturation and extensive proteolysis during heat shock and oxidative stress. Aggregated proteins bound to the IbpAB complex are more efficiently refolded and reactivated by the ATP-dependent chaperone systems ClpB and DnaK/DnaJ/GrpE. Its activity is ATP-independent.
messages: Belongs to the small heat shock protein (HSP20) family.
messages: Cytoplasm
messages: Monomer. Forms homomultimers of about 100-150 subunits at optimal growth temperatures. Conformation changes to monomers at high temperatures or high ionic concentrations.

2052056:CTZ24 RS18525
gene id: 2052056:CTZ24_RS18525
uniprot id: A0A6I6B4Q1
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

2052056:CTZ24 RS18850
gene id: 2052056:CTZ24_RS18850
uniprot id: A0A6I6AYX8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Gfo/Idh/MocA family.
messages: Homotetramer.
messages: Involved in the oxidation of myo-inositol (MI) to 2-keto-myo-inositol (2KMI or 2-inosose).

2052056:CTZ24 RS14895
gene id: 2052056:CTZ24_RS14895
uniprot id: A0A6I6AWY0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 23 kDa subunit family.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell membrane
messages: NDH-1 is composed of 13 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

2052056:CTZ24 RS06275
gene id: 2052056:CTZ24_RS06275
uniprot id: A0A6I6ASA8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane

2052056:CTZ24 RS17020
gene id: 2052056:CTZ24_RS17020
uniprot id: A0A6I6AW71
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CutC family.
messages: Cytoplasm
messages: Once thought to be involved in copper homeostasis, experiments in E.coli have shown this is not the case.

2052056:CTZ24 RS04925
gene id: 2052056:CTZ24_RS04925
uniprot id: A0A6I6AUP2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

2052056:CTZ24 RS10285
gene id: 2052056:CTZ24_RS10285
uniprot id: A0A6I6AXG3
names: Similarity
messages: Belongs to the ABC transporter superfamily. Drug exporter-2 (TC 3.A.1.117) family.

2052056:CTZ24 RS02445
gene id: 2052056:CTZ24_RS02445
uniprot id: A0A6I6APN5
names: Similarity
messages: Belongs to the BolA/IbaG family.

2052056:CTZ24 RS13305
gene id: 2052056:CTZ24_RS13305
uniprot id: A0A6I6AYB6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.
messages: Binds 2 iron ions per subunit.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.
messages: Tetramer of two alpha and two beta subunits.

2052056:CTZ24 RS17085
gene id: 2052056:CTZ24_RS17085
uniprot id: A0A6I6AY31
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvB family.
messages: Cytoplasm
messages: Has 3 domains, the large (RuvB-L) and small ATPase (RuvB-S) domains and the C-terminal head (RuvB-H) domain. The head domain binds DNA, while the ATPase domains jointly bind ATP, ADP or are empty depending on the state of the subunit in the translocation cycle. During a single DNA translocation step the structure of each domain remains the same, but their relative positions change.
messages: Homohexamer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time. Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange. Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration. The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration. Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.

2052056:CTZ24 RS19320
gene id: 2052056:CTZ24_RS19320
uniprot id: A0A6I6AZ51
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

2052056:CTZ24 RS19795
gene id: 2052056:CTZ24_RS19795
uniprot id: A0A6I6AXU9
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

2052056:CTZ24 RS05400
gene id: 2052056:CTZ24_RS05400
uniprot id: A0A6I6AY38
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

2052056:CTZ24 RS17830
gene id: 2052056:CTZ24_RS17830
uniprot id: A0A6I6B1B8
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FBPase class 1 family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.

2052056:CTZ24 RS15685
gene id: 2052056:CTZ24_RS15685
uniprot id: A0A6I6AXC6
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the C-terminal section; belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: In the N-terminal section; belongs to the histidinol-phosphatase family.

2052056:CTZ24 RS00705
gene id: 2052056:CTZ24_RS00705
uniprot id: A0A6I6AMT6
names: Similarity
messages: Belongs to the peptidase M16 family.

2052056:CTZ24 RS17925
gene id: 2052056:CTZ24_RS17925
uniprot id: A0A6I6B199
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with bS18 to 16S ribosomal RNA.

2052056:CTZ24 RS09505
gene id: 2052056:CTZ24_RS09505
uniprot id: A0A6I6B0E4
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

2052056:CTZ24 RS01550
gene id: 2052056:CTZ24_RS01550
uniprot id: A0A6I6ANB6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S24 family.
messages: Homodimer.
messages: Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. Binds to the 16 bp palindromic sequence 5'-CTGTATATATATACAG-3'. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.

2052056:CTZ24 RS04355
gene id: 2052056:CTZ24_RS04355
uniprot id: A0A6I6APU9
names: Function
messages: Acetylation of prosthetic group (2-(5''-phosphoribosyl)-3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase.

2052056:CTZ24 RS04635
gene id: 2052056:CTZ24_RS04635
uniprot id: A0A6I6AY10
names: Function
messages: This protein is a positive regulator for the phosphate regulon. Transcription of this operon is positively regulated by PhoB and PhoR when phosphate is limited.

2052056:CTZ24 RS03235
gene id: 2052056:CTZ24_RS03235
uniprot id: A0A6I6AQD9
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

2052056:CTZ24 RS25765
gene id: 2052056:CTZ24_RS25765
uniprot id: A0A6I6BC68
names: Similarity
messages: Belongs to the DapA family.

2052056:CTZ24 RS16455
gene id: 2052056:CTZ24_RS16455
uniprot id: A0A6I6AXR9
names: Cofactor
messages: Binds 1 Fe(2+) ion per subunit.

2052056:CTZ24 RS01125
gene id: 2052056:CTZ24_RS01125
uniprot id: A0A6I6ARC5
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

2052056:CTZ24 RS13860
gene id: 2052056:CTZ24_RS13860
uniprot id: A0A6I6AWE5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

2052056:CTZ24 RS08545
gene id: 2052056:CTZ24_RS08545
uniprot id: A0A6I6AWS0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CheZ family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P).

2052056:CTZ24 RS13565
gene id: 2052056:CTZ24_RS13565
uniprot id: A0A6I6AUU3
names: Similarity
messages: Belongs to the UPF0125 (RnfH) family.

2052056:CTZ24 RS10760
gene id: 2052056:CTZ24_RS10760
uniprot id: A0A6I6AUJ8
names: Similarity
messages: Belongs to the SUI1 family.

2052056:CTZ24 RS14735
gene id: 2052056:CTZ24_RS14735
uniprot id: A0A6I6AZR4
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2052056:CTZ24 RS17845
gene id: 2052056:CTZ24_RS17845
uniprot id: A0A6I6AWW2
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0756 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2052056:CTZ24 RS04585
gene id: 2052056:CTZ24_RS04585
uniprot id: A0A6I6AXZ7
names: Function
names: Similarity
messages: Belongs to the nucleoside phosphorylase PpnP family.
messages: Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions.

2052056:CTZ24 RS03525
gene id: 2052056:CTZ24_RS03525
uniprot id: A0A6I6APF8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA gyrase inhibitor YacG family.
messages: Binds 1 zinc ion.
messages: Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase.
messages: Interacts with GyrB.

2052056:CTZ24 RS04140
gene id: 2052056:CTZ24_RS04140
uniprot id: A0A6I6AXE1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

2052056:CTZ24 RS11350
gene id: 2052056:CTZ24_RS11350
uniprot id: A0A6I6ATS2
names: Similarity
messages: Belongs to the peptidase S41A family.

2052056:CTZ24 RS02740
gene id: 2052056:CTZ24_RS02740
uniprot id: A0A6I6AQ70
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm

2052056:CTZ24 RS12390
gene id: 2052056:CTZ24_RS12390
uniprot id: A0A6I6ATU7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class II fructose-bisphosphate aldolase family.
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.
messages: Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.

2052056:CTZ24 RS04920
gene id: 2052056:CTZ24_RS04920
uniprot id: A0A6I6AQ53
names: Similarity
messages: Belongs to the P(II) protein family.

2052056:CTZ24 RS15320
gene id: 2052056:CTZ24_RS15320
uniprot id: A0A6I6AZG3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. Drug exporter-2 (TC 3.A.1.117) family.
messages: Cell inner membrane
messages: Part of an ABC transporter complex involved in carbohydrate import. Could be involved in ribose, galactose and/or methyl galactoside import. Responsible for energy coupling to the transport system.

2052056:CTZ24 RS24965
gene id: 2052056:CTZ24_RS24965
uniprot id: A0A6I6B155
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NifD/NifK/NifE/NifN family.
messages: Tetramer of two alpha and two beta chains. Forms complex with the iron protein (nitrogenase component 2).
messages: This molybdenum-iron protein is part of the nitrogenase complex that catalyzes the key enzymatic reactions in nitrogen fixation.

2052056:CTZ24 RS12020
gene id: 2052056:CTZ24_RS12020
uniprot id: A0A6I6AV97
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

2052056:CTZ24 RS06615
gene id: 2052056:CTZ24_RS06615
uniprot id: A0A6I6AR90
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein PotD/PotF family.
messages: Periplasm
messages: Required for the activity of the bacterial periplasmic transport system of putrescine.

2052056:CTZ24 RS04730
gene id: 2052056:CTZ24_RS04730
uniprot id: A0A6I6AQQ0
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

2052056:CTZ24 RS02270
gene id: 2052056:CTZ24_RS02270
uniprot id: A0A6I6ATK1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

2052056:CTZ24 RS00500
gene id: 2052056:CTZ24_RS00500
uniprot id: A0A6I6AMU0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

2052056:CTZ24 RS05630
gene id: 2052056:CTZ24_RS05630
uniprot id: A0A6I6AQF8
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Fur family.
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.

2052056:CTZ24 RS04010
gene id: 2052056:CTZ24_RS04010
uniprot id: A0A6I6AR80
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

2052056:CTZ24 RS11065
gene id: 2052056:CTZ24_RS11065
uniprot id: A0A6I6AT59
names: Cofactor
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.
messages: Probably binds two magnesium or manganese ions per subunit.

2052056:CTZ24 RS03490
gene id: 2052056:CTZ24_RS03490
uniprot id: A0A6I6AQ52
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsQ/DivIB family. FtsQ subfamily.
messages: Cell inner membrane
messages: Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly.
messages: Part of a complex composed of FtsB, FtsL and FtsQ.

2052056:CTZ24 RS02645
gene id: 2052056:CTZ24_RS02645
uniprot id: A0A6I6AWM7
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cell membrane
messages: Homodimer.
messages: May be involved in cell division.

2052056:CTZ24 RS18400
gene id: 2052056:CTZ24_RS18400
uniprot id: A0A6I6B1J7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

2052056:CTZ24 RS10690
gene id: 2052056:CTZ24_RS10690
uniprot id: A0A6I6AWV9
names: Function
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.
messages: Catalyzes the reduction of a carbon-carbon double bond in an enoyl moiety that is covalently linked to an acyl carrier protein (ACP). Involved in the elongation cycle of fatty acid which are used in the lipid metabolism and in the biotin biosynthesis.

2052056:CTZ24 RS10765
gene id: 2052056:CTZ24_RS10765
uniprot id: A0A6I6ATG4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the OMP decarboxylase family. Type 1 subfamily.
messages: Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
messages: Homodimer.

2052056:CTZ24 RS07830
gene id: 2052056:CTZ24_RS07830
uniprot id: A0A6I6B006
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.

2052056:CTZ24 RS07030
gene id: 2052056:CTZ24_RS07030
uniprot id: A0A6I6AUX6
names: Subcellular Location Annotation
messages: Cell inner membrane

2052056:CTZ24 RS13300
gene id: 2052056:CTZ24_RS13300
uniprot id: A0A6I6B2F7
names: Similarity
messages: Belongs to the ABC transporter superfamily. Drug exporter-2 (TC 3.A.1.117) family.

2052056:CTZ24 RS03110
gene id: 2052056:CTZ24_RS03110
uniprot id: A0A6I6AQT1
names: Similarity
messages: Belongs to the ABC transporter superfamily. Drug exporter-2 (TC 3.A.1.117) family.

2052056:CTZ24 RS13840
gene id: 2052056:CTZ24_RS13840
uniprot id: A0A6I6AYP7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

2052056:CTZ24 RS06865
gene id: 2052056:CTZ24_RS06865
uniprot id: A0A6I6AZG5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MukE family.
messages: Interacts, and probably forms a ternary complex, with MukF and MukB. The complex formation is stimulated by calcium or magnesium.
messages: Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF.
messages: nucleoid

2052056:CTZ24 RS17650
gene id: 2052056:CTZ24_RS17650
uniprot id: A0A6I6B0P8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TerC family.
messages: Membrane

2052056:CTZ24 RS12835
gene id: 2052056:CTZ24_RS12835
uniprot id: A0A6I6AVV2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2052056:CTZ24 RS16155
gene id: 2052056:CTZ24_RS16155
uniprot id: A0A6I6B4R8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2052056:CTZ24 RS00990
gene id: 2052056:CTZ24_RS00990
uniprot id: A0A6I6ARB0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

2052056:CTZ24 RS19830
gene id: 2052056:CTZ24_RS19830
uniprot id: A0A6I6AXJ5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase PH family.
messages: Homohexameric ring arranged as a trimer of dimers.
messages: Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.

2052056:CTZ24 RS00260
gene id: 2052056:CTZ24_RS00260
uniprot id: A0A6I6ASE3
names: Function
names: Similarity
messages: Belongs to the DnaT family.
messages: This protein is required for primosome-dependent normal DNA replication; it is also involved in inducing stable DNA replication during SOS response. It forms, in concert with DnaB protein and other prepriming proteins DnaC, N, N', N'' a prepriming protein complex on the specific site of the template DNA recognized by protein N'.

2052056:CTZ24 RS03280
gene id: 2052056:CTZ24_RS03280
uniprot id: A0A6I6AQ21
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.
messages: Homodimer.

2052056:CTZ24 RS07720
gene id: 2052056:CTZ24_RS07720
uniprot id: A0A6I6ASU8
names: Function
names: Similarity
messages: Belongs to the TrhO family.
messages: Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs.

2052056:CTZ24 RS14075
gene id: 2052056:CTZ24_RS14075
uniprot id: A0A6I6AY05
names: Similarity
messages: Belongs to the SAICAR synthetase family.

2052056:CTZ24 RS01345
gene id: 2052056:CTZ24_RS01345
uniprot id: A0A6I6ARF9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily.
messages: Cell inner membrane
messages: Involved in the import of queuosine (Q) precursors, required for Q precursor salvage.

2052056:CTZ24 RS18490
gene id: 2052056:CTZ24_RS18490
uniprot id: A0A6I6B162
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

2052056:CTZ24 RS24200
gene id: 2052056:CTZ24_RS24200
uniprot id: A0A6I6B8F5
names: Similarity
messages: Belongs to the MipA/OmpV family.

2052056:CTZ24 RS13785
gene id: 2052056:CTZ24_RS13785
uniprot id: A0A6I6AZ98
names: Subcellular Location Annotation
messages: Membrane

2052056:CTZ24 RS12905
gene id: 2052056:CTZ24_RS12905
uniprot id: A0A6I6B320
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HpcH/HpaI aldolase family. KDGluc aldolase subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible retro-aldol cleavage of both 5-keto-4-deoxy-D-glucarate and 2-keto-3-deoxy-D-glucarate to pyruvate and tartronic semialdehyde.
messages: Homohexamer; trimer of dimers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2052056:CTZ24 RS24960
gene id: 2052056:CTZ24_RS24960
uniprot id: A0A6I6B2U8
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the NifH/BchL/ChlL family.
messages: Binds 1 [4Fe-4S] cluster per dimer.
messages: Homodimer.
messages: The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components: the iron protein and the molybdenum-iron protein.
messages: The reversible ADP-ribosylation of Arg inactivates the nitrogenase reductase and regulates nitrogenase activity.
messages: The reversible ADP-ribosylation of Arg-101 inactivates the nitrogenase reductase and regulates nitrogenase activity.

2052056:CTZ24 RS10960
gene id: 2052056:CTZ24_RS10960
uniprot id: A0A6I6AXU5
names: Similarity
messages: Belongs to the ABC transporter superfamily. Drug exporter-2 (TC 3.A.1.117) family.

2052056:CTZ24 RS16165
gene id: 2052056:CTZ24_RS16165
uniprot id: A0A6I6AZX5
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

2052056:CTZ24 RS02195
gene id: 2052056:CTZ24_RS02195
uniprot id: A0A6I6API6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HAK/KUP transporter (TC 2.A.72) family.
messages: Cell membrane
messages: Membrane
messages: Responsible for the low-affinity transport of potassium into the cell. Likely operates as a K(+):H(+) symporter.

2052056:CTZ24 RS06600
gene id: 2052056:CTZ24_RS06600
uniprot id: A0A6I6AZA0
names: Similarity
messages: Belongs to the flavin oxidoreductase frp family.

2052056:CTZ24 RS00030
gene id: 2052056:CTZ24_RS00030
uniprot id: A0A6I6ANE4
names: Similarity
messages: Belongs to the ABC transporter superfamily. Drug exporter-2 (TC 3.A.1.117) family.

2052056:CTZ24 RS13640
gene id: 2052056:CTZ24_RS13640
uniprot id: A0A6I6AYK9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Membrane

2052056:CTZ24 RS00625
gene id: 2052056:CTZ24_RS00625
uniprot id: A0A6I6ANN7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family.
messages: Catalytic subunit of cellulose synthase. It polymerizes uridine 5'-diphosphate glucose to cellulose.
messages: Cell inner membrane
messages: Membrane

2052056:CTZ24 RS14920
gene id: 2052056:CTZ24_RS14920
uniprot id: A0A6I6AZV0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 2 family.
messages: Cell membrane
messages: Composed of 13 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: Membrane
messages: NDH-1 is composed of 13 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

2052056:CTZ24 RS07820
gene id: 2052056:CTZ24_RS07820
uniprot id: A0A6I6ASW8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

2052056:CTZ24 RS01330
gene id: 2052056:CTZ24_RS01330
uniprot id: A0A6I6AVT2
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.
messages: Synthesizes alpha-1,4-glucan chains using ADP-glucose.

2052056:CTZ24 RS16435
gene id: 2052056:CTZ24_RS16435
uniprot id: A0A6I6AVU4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

2052056:CTZ24 RS14390
gene id: 2052056:CTZ24_RS14390
uniprot id: A0A6I6AUY0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family.
messages: Membrane

2052056:CTZ24 RS13015
gene id: 2052056:CTZ24_RS13015
uniprot id: A0A6I6AY82
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).
messages: Homodimer.

2052056:CTZ24 RS08635
gene id: 2052056:CTZ24_RS08635
uniprot id: A0A6I6ATC2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.
messages: Homodimer.

2052056:CTZ24 RS18510
gene id: 2052056:CTZ24_RS18510
uniprot id: A0A6I6AYT1
names: Similarity
messages: Belongs to the DsrF/TusC family.

2052056:CTZ24 RS01560
gene id: 2052056:CTZ24_RS01560
uniprot id: A0A6I6AQ17
names: Similarity
messages: Belongs to the UPF0337 (CsbD) family.

2052056:CTZ24 RS11595
gene id: 2052056:CTZ24_RS11595
uniprot id: A0A6I6AY68
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family. ParE type 1 subfamily.
messages: Heterotetramer composed of ParC and ParE.
messages: Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.

2052056:CTZ24 RS06625
gene id: 2052056:CTZ24_RS06625
uniprot id: A0A6I6AVK5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

2052056:CTZ24 RS12890
gene id: 2052056:CTZ24_RS12890
uniprot id: A0A6I6AUI2
names: Subcellular Location Annotation
messages: Membrane

2052056:CTZ24 RS18960
gene id: 2052056:CTZ24_RS18960
uniprot id: A0A6I6B4X4
names: Subcellular Location Annotation
messages: Membrane

2052056:CTZ24 RS03505
gene id: 2052056:CTZ24_RS03505
uniprot id: A0A6I6AX69
names: Function
names: Similarity
messages: Belongs to the LpxC family.
messages: Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.

2052056:CTZ24 RS03430
gene id: 2052056:CTZ24_RS03430
uniprot id: A0A6I6ATW6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MraZ family.
messages: Forms oligomers.
messages: Negatively regulates its own expression and that of the subsequent genes in the proximal part of the division and cell wall (dcw) gene cluster. Acts by binding directly to DNA. May also regulate the expression of genes outside the dcw cluster.
messages: nucleoid

2052056:CTZ24 RS25760
gene id: 2052056:CTZ24_RS25760
uniprot id: A0A6I6B9D6
names: PTM
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Hydantoinase/dihydropyrimidinase family.
messages: Carbamylation allows a single lysine to coordinate two divalent metal cations.

2052056:CTZ24 RS25670
gene id: 2052056:CTZ24_RS25670
uniprot id: A0A6I6B1D9
names: Subcellular Location Annotation
messages: Membrane

2052056:CTZ24 RS19515
gene id: 2052056:CTZ24_RS19515
uniprot id: A0A6I6AXH0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.