203122:SDE RS19560
gene id: 203122:SDE_RS19560
uniprot id: Q21E80
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Also exhibits azoreductase activity. Catalyzes the reductive cleavage of the azo bond in aromatic azo compounds to the corresponding amines.
messages: Belongs to the azoreductase type 1 family.
messages: Binds 1 FMN per subunit.
messages: Homodimer.
messages: Quinone reductase that provides resistance to thiol-specific stress caused by electrophilic quinones.

203122:SDE RS08805
gene id: 203122:SDE_RS08805
uniprot id: Q21K36
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

203122:SDE RS10645
gene id: 203122:SDE_RS10645
uniprot id: Q21J41
names: Similarity
messages: Belongs to the bacterial solute-binding protein 5 family.

203122:SDE RS06580
gene id: 203122:SDE_RS06580
uniprot id: Q21LB3
names: Similarity
messages: Belongs to the phosphohexose mutase family.

203122:SDE RS16570
gene id: 203122:SDE_RS16570
uniprot id: Q21FV8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

203122:SDE RS04500
gene id: 203122:SDE_RS04500
uniprot id: Q21MG4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

203122:SDE RS08295
gene id: 203122:SDE_RS08295
uniprot id: Q21KD4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial histone-like protein family.
messages: Heterodimer of an alpha and a beta chain.
messages: This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.

203122:SDE RS06585
gene id: 203122:SDE_RS06585
uniprot id: Q21LB2
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

203122:SDE RS11700
gene id: 203122:SDE_RS11700
uniprot id: Q21II4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Monomer.

203122:SDE RS06630
gene id: 203122:SDE_RS06630
uniprot id: Q21LA3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

203122:SDE RS00375
gene id: 203122:SDE_RS00375
uniprot id: Q21PP2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
messages: Single-chain monomer with multiple functions.

203122:SDE RS14320
gene id: 203122:SDE_RS14320
uniprot id: Q21H33
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Fur family.
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.

203122:SDE RS11445
gene id: 203122:SDE_RS11445
uniprot id: Q21IN5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliJ family.
messages: Cell membrane
messages: Membrane

203122:SDE RS05125
gene id: 203122:SDE_RS05125
uniprot id: Q21M46
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

203122:SDE RS07610
gene id: 203122:SDE_RS07610
uniprot id: Q21KR3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ThiG family.
messages: Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
messages: Cytoplasm
messages: Homotetramer. Forms heterodimers with either ThiH or ThiS.

203122:SDE RS00800
gene id: 203122:SDE_RS00800
uniprot id: Q21PG0
names: Subcellular Location Annotation
messages: Membrane

203122:SDE RS14340
gene id: 203122:SDE_RS14340
uniprot id: Q21H29
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

203122:SDE RS09220
gene id: 203122:SDE_RS09220
uniprot id: Q21JV7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
messages: Cell inner membrane
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

203122:SDE RS10465
gene id: 203122:SDE_RS10465
uniprot id: Q21J77
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.
messages: There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors.

203122:SDE RS13385
gene id: 203122:SDE_RS13385
uniprot id: Q21HL6
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
messages: In the C-terminal section; belongs to the NAD synthetase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

203122:SDE RS01155
gene id: 203122:SDE_RS01155
uniprot id: Q21P98
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiK family.
messages: Cytoplasm
messages: Required for efficient ubiquinone (coenzyme Q) biosynthesis. UbiK is probably an accessory factor of Ubi enzymes and facilitates ubiquinone biosynthesis by acting as an assembly factor, a targeting factor, or both.

203122:SDE RS16635
gene id: 203122:SDE_RS16635
uniprot id: Q21FU5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptA family.
messages: Component of the lipopolysaccharide transport and assembly complex.
messages: Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm.
messages: Periplasm

203122:SDE RS12720
gene id: 203122:SDE_RS12720
uniprot id: Q21HY9
names: Similarity
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.

203122:SDE RS11535
gene id: 203122:SDE_RS11535
uniprot id: Q21IL6
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Secreted

203122:SDE RS20300
gene id: 203122:SDE_RS20300
uniprot id: Q21DU2
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

203122:SDE RS12355
gene id: 203122:SDE_RS12355
uniprot id: Q21I61
names: Function
names: Similarity
messages: Belongs to the MoaB/Mog family.
messages: May be involved in the biosynthesis of molybdopterin.

203122:SDE RS12945
gene id: 203122:SDE_RS12945
uniprot id: Q21HU4
names: Subcellular Location Annotation
messages: Membrane

203122:SDE RS17315
gene id: 203122:SDE_RS17315
uniprot id: Q21FG6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm

203122:SDE RS21525
gene id: 203122:SDE_RS21525
uniprot id: Q21FY5
names: Function
names: Similarity
messages: Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl-L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity).
messages: In the C-terminal section; belongs to the methyltransferase superfamily.
messages: In the N-terminal section; belongs to the AB hydrolase superfamily. Carboxylesterase BioH family.
messages: The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity).

203122:SDE RS05025
gene id: 203122:SDE_RS05025
uniprot id: Q21M65
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

203122:SDE RS02855
gene id: 203122:SDE_RS02855
uniprot id: Q21ND8
names: Similarity
messages: Belongs to the UPF0047 family.

203122:SDE RS07015
gene id: 203122:SDE_RS07015
uniprot id: Q21L29
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase D family.
messages: Cytoplasm
messages: Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides.

203122:SDE RS02045
gene id: 203122:SDE_RS02045
uniprot id: Q21NS7
names: Function
names: Similarity
messages: Acts on leucine, isoleucine and valine.
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

203122:SDE RS04935
gene id: 203122:SDE_RS04935
uniprot id: Q21M83
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

203122:SDE RS04445
gene id: 203122:SDE_RS04445
uniprot id: Q21MH5
names: Function
names: Similarity
messages: Belongs to the transpeptidase family. FtsI subfamily.
messages: Catalyzes cross-linking of the peptidoglycan cell wall at the division septum.

203122:SDE RS09305
gene id: 203122:SDE_RS09305
uniprot id: Q21JU0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCF family. Uup subfamily.
messages: Cytoplasm
messages: Probably plays a role in ribosome assembly or function. May be involved in resolution of branched DNA intermediates that result from template switching in postreplication gaps. Binds DNA and has ATPase activity.

203122:SDE RS21125
gene id: 203122:SDE_RS21125
uniprot id: Q21MX9
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

203122:SDE RS13760
gene id: 203122:SDE_RS13760
uniprot id: Q21HE1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

203122:SDE RS11220
gene id: 203122:SDE_RS11220
uniprot id: Q21IS9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

203122:SDE RS04475
gene id: 203122:SDE_RS04475
uniprot id: Q21MG9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell inner membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).

203122:SDE RS02700
gene id: 203122:SDE_RS02700
uniprot id: Q21NG9
names: Function
names: Similarity
messages: Belongs to the glutaredoxin family.
messages: Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins.

203122:SDE RS06470
gene id: 203122:SDE_RS06470
uniprot id: Q21LD5
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.

203122:SDE RS19300
gene id: 203122:SDE_RS19300
uniprot id: Q21ED0
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

203122:SDE RS18070
gene id: 203122:SDE_RS18070
uniprot id: Q21F19
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.
messages: Forms an icosahedral capsid composed of 60 subunits, arranged as a dodecamer of pentamers.

203122:SDE RS18310
gene id: 203122:SDE_RS18310
uniprot id: Q21EX2
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

203122:SDE RS10275
gene id: 203122:SDE_RS10275
uniprot id: Q21JB5
names: Subcellular Location Annotation
messages: Membrane

203122:SDE RS09400
gene id: 203122:SDE_RS09400
uniprot id: Q21JS1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrB/RnfD family.
messages: Cell inner membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

203122:SDE RS10475
gene id: 203122:SDE_RS10475
uniprot id: Q21J75
names: Similarity
messages: Belongs to the peptidase S41A family.

203122:SDE RS03315
gene id: 203122:SDE_RS03315
uniprot id: Q21N48
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

203122:SDE RS17780
gene id: 203122:SDE_RS17780
uniprot id: Q21F74
names: Similarity
messages: Belongs to the isochorismate synthase family.

203122:SDE RS15035
gene id: 203122:SDE_RS15035
uniprot id: Q21GP7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

203122:SDE RS15575
gene id: 203122:SDE_RS15575
uniprot id: Q21GE3
names: Similarity
messages: Belongs to the GST superfamily.

203122:SDE RS19555
gene id: 203122:SDE_RS19555
uniprot id: Q21E81
names: Similarity
messages: Belongs to the pirin family.

203122:SDE RS10450
gene id: 203122:SDE_RS10450
uniprot id: Q21J80
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

203122:SDE RS11060
gene id: 203122:SDE_RS11060
uniprot id: Q21IW1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
messages: Cell inner membrane
messages: Membrane

203122:SDE RS18625
gene id: 203122:SDE_RS18625
uniprot id: Q21ER1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

203122:SDE RS19305
gene id: 203122:SDE_RS19305
uniprot id: Q21EC9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

203122:SDE RS03090
gene id: 203122:SDE_RS03090
uniprot id: Q21N91
names: Subcellular Location Annotation
messages: Cytoplasm

203122:SDE RS08385
gene id: 203122:SDE_RS08385
uniprot id: Q21KB7
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

203122:SDE RS16655
gene id: 203122:SDE_RS16655
uniprot id: Q21FU1
names: Function
names: Similarity
messages: Belongs to the RapZ-like family.
messages: Displays ATPase and GTPase activities.

203122:SDE RS13970
gene id: 203122:SDE_RS13970
uniprot id: Q21HA0
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

203122:SDE RS09095
gene id: 203122:SDE_RS09095
uniprot id: Q21JY2
names: Similarity
messages: Belongs to the peptidase M1 family.

203122:SDE RS18090
gene id: 203122:SDE_RS18090
uniprot id: Q21F15
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

203122:SDE RS08470
gene id: 203122:SDE_RS08470
uniprot id: Q21KA1
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. TrmA subfamily.
messages: Dual-specificity methyltransferase that catalyzes the formation of 5-methyluridine at position 54 (m5U54) in all tRNAs, and that of position 341 (m5U341) in tmRNA (transfer-mRNA).

203122:SDE RS16355
gene id: 203122:SDE_RS16355
uniprot id: Q21G00
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
messages: Membrane

203122:SDE RS20695
gene id: 203122:SDE_RS20695
uniprot id: Q21DL5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
messages: Cytoplasm
messages: Homotrimer.
messages: In the C-terminal section; belongs to the transferase hexapeptide repeat family.
messages: In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.

203122:SDE RS17390
gene id: 203122:SDE_RS17390
uniprot id: Q21FF1
names: Similarity
messages: Belongs to the outer membrane OOP (TC 1.B.6) superfamily. OmpA family.

203122:SDE RS05110
gene id: 203122:SDE_RS05110
uniprot id: Q21M49
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

203122:SDE RS00020
gene id: 203122:SDE_RS00020
uniprot id: Q21PW3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

203122:SDE RS13165
gene id: 203122:SDE_RS13165
uniprot id: Q21HQ3
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

203122:SDE RS05555
gene id: 203122:SDE_RS05555
uniprot id: Q21LV8
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

203122:SDE RS18855
gene id: 203122:SDE_RS18855
uniprot id: Q21EL5
names: Subcellular Location Annotation
messages: Membrane

203122:SDE RS01305
gene id: 203122:SDE_RS01305
uniprot id: Q21P69
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Cell inner membrane
messages: Homoheptamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mechanosensitive channel that participates in the regulation of osmotic pressure changes within the cell, opening in response to stretch forces in the membrane lipid bilayer, without the need for other proteins. Contributes to normal resistance to hypoosmotic shock. Forms an ion channel of 1.0 nanosiemens conductance with a slight preference for anions.
messages: Membrane

203122:SDE RS01785
gene id: 203122:SDE_RS01785
uniprot id: Q21NX9
names: Function
names: Similarity
messages: Belongs to the Fe(2+)-trafficking protein family.
messages: Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes.

203122:SDE RS05080
gene id: 203122:SDE_RS05080
uniprot id: Q21M54
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

203122:SDE RS04780
gene id: 203122:SDE_RS04780
uniprot id: Q21MA8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.
messages: Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.
messages: Cytoplasm
messages: Homodimer.

203122:SDE RS11260
gene id: 203122:SDE_RS11260
uniprot id: Q21IS1
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

203122:SDE RS17675
gene id: 203122:SDE_RS17675
uniprot id: Q21F95
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

203122:SDE RS11470
gene id: 203122:SDE_RS11470
uniprot id: Q21IN0
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliE family.

203122:SDE RS12390
gene id: 203122:SDE_RS12390
uniprot id: Q21I54
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

203122:SDE RS00140
gene id: 203122:SDE_RS00140
uniprot id: Q21PT9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the shikimate dehydrogenase family.
messages: Homodimer.
messages: Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).

203122:SDE RS17785
gene id: 203122:SDE_RS17785
uniprot id: Q21F73
names: Function
names: Similarity
names: Subunit
messages: Belongs to the P-Pant transferase superfamily. EntD family.
messages: EntB, EntD, EntE, and EntF form a multienzyme complex called enterobactin synthase.
messages: Involved in the biosynthesis of the siderophore enterobactin (enterochelin), which is a macrocyclic trimeric lactone of N-(2,3-dihydroxybenzoyl)-serine. The serine trilactone serves as a scaffolding for the three catechol functionalities that provide hexadentate coordination for the tightly ligated iron(2+) atoms. Plays an essential role in the assembly of the enterobactin by catalyzing the transfer of the 4'-phosphopantetheine (Ppant) moiety from coenzyme A to the apo-domains of both EntB (ArCP domain) and EntF (PCP domain) to yield their holo-forms which make them competent for the activation of 2,3-dihydroxybenzoate (DHB) and L-serine, respectively.

203122:SDE RS17955
gene id: 203122:SDE_RS17955
uniprot id: Q21F41
names: Similarity
messages: Belongs to the GST superfamily.

203122:SDE RS02655
gene id: 203122:SDE_RS02655
uniprot id: Q21NH7
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

203122:SDE RS15325
gene id: 203122:SDE_RS15325
uniprot id: Q21GJ1
names: Similarity
messages: Belongs to the glutathione peroxidase family.

203122:SDE RS00200
gene id: 203122:SDE_RS00200
uniprot id: Q21PS7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COX11/CtaG family.
messages: Cell inner membrane
messages: Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I.

203122:SDE RS00830
gene id: 203122:SDE_RS00830
uniprot id: Q21PF4
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

203122:SDE RS18710
gene id: 203122:SDE_RS18710
uniprot id: Q21EP4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial secretin family. GSP D subfamily.
messages: Cell outer membrane
messages: Membrane

203122:SDE RS13735
gene id: 203122:SDE_RS13735
uniprot id: Q21HE6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LpxL/LpxM/LpxP family.
messages: Catalyzes the transfer of an acyl chain from an acyl-[acyl-carrier-protein] (ACP) to a Kdo(2)-lipid IV(A) to form a Kdo(2)-(acyl)-lipid IV(A).
messages: Cell inner membrane

203122:SDE RS02565
gene id: 203122:SDE_RS02565
uniprot id: Q21NJ5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

203122:SDE RS04910
gene id: 203122:SDE_RS04910
uniprot id: Q21M87
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

203122:SDE RS04110
gene id: 203122:SDE_RS04110
uniprot id: Q21MP2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 1 subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

203122:SDE RS09075
gene id: 203122:SDE_RS09075
uniprot id: Q21JY6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.

203122:SDE RS20750
gene id: 203122:SDE_RS20750
uniprot id: Q21DK4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell inner membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.

203122:SDE RS16710
gene id: 203122:SDE_RS16710
uniprot id: Q21FT0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

203122:SDE RS04025
gene id: 203122:SDE_RS04025
uniprot id: Q21MQ9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COQ7 family.
messages: Binds 2 iron ions per subunit.
messages: Catalyzes the hydroxylation of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol during ubiquinone biosynthesis.
messages: Cell membrane

203122:SDE RS12820
gene id: 203122:SDE_RS12820
uniprot id: Q21HW9
names: Similarity
messages: Belongs to the MipA/OmpV family.

203122:SDE RS02060
gene id: 203122:SDE_RS02060
uniprot id: Q21NS4
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

203122:SDE RS16225
gene id: 203122:SDE_RS16225
uniprot id: Q21G26
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

203122:SDE RS16605
gene id: 203122:SDE_RS16605
uniprot id: Q21FV1
names: Similarity
messages: Belongs to the BolA/IbaG family.

203122:SDE RS08710
gene id: 203122:SDE_RS08710
uniprot id: Q21K55
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell inner membrane
messages: Membrane

203122:SDE RS21280
gene id: 203122:SDE_RS21280
uniprot id: Q21JY4
names: Subcellular Location Annotation
messages: Membrane

203122:SDE RS06260
gene id: 203122:SDE_RS06260
uniprot id: Q21LH7
names: Function
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
messages: Catalyzes reversively the conversion of L-aspartate beta-semialdehyde (ASA) to L-2,4-diaminobutyrate (DABA) by transamination with L-glutamate.

203122:SDE RS03040
gene id: 203122:SDE_RS03040
uniprot id: Q21NA3
names: Subcellular Location Annotation
messages: Membrane

203122:SDE RS07205
gene id: 203122:SDE_RS07205
uniprot id: Q21KZ2
names: Subcellular Location Annotation
messages: Membrane

203122:SDE RS00955
gene id: 203122:SDE_RS00955
uniprot id: Q21PD1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. UvrD subfamily.
messages: Homodimer.
messages: Rep helicase is a single-stranded DNA-dependent ATPase involved in DNA replication; it can initiate unwinding at a nick in the DNA. It binds to the single-stranded DNA and acts in a progressive fashion along the DNA in the 3' to 5' direction.

203122:SDE RS19200
gene id: 203122:SDE_RS19200
uniprot id: Q21EE9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm

203122:SDE RS13170
gene id: 203122:SDE_RS13170
uniprot id: Q21HQ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

203122:SDE RS00115
gene id: 203122:SDE_RS00115
uniprot id: Q21PV5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

203122:SDE RS21135
gene id: 203122:SDE_RS21135
uniprot id: Q21MX6
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

203122:SDE RS12855
gene id: 203122:SDE_RS12855
uniprot id: Q21HW2
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

203122:SDE RS20715
gene id: 203122:SDE_RS20715
uniprot id: Q21DL1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

203122:SDE RS11755
gene id: 203122:SDE_RS11755
uniprot id: Q21IH3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell inner membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

203122:SDE RS09920
gene id: 203122:SDE_RS09920
uniprot id: Q21JI1
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

203122:SDE RS13595
gene id: 203122:SDE_RS13595
uniprot id: Q21HH4
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by GTP. Inhibited by UTP.
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.

203122:SDE RS12360
gene id: 203122:SDE_RS12360
uniprot id: Q21I60
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

203122:SDE RS06700
gene id: 203122:SDE_RS06700
uniprot id: Q21L89
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FBPase class 1 family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.

203122:SDE RS16085
gene id: 203122:SDE_RS16085
uniprot id: Q21G51
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell inner membrane
messages: Membrane

203122:SDE RS11195
gene id: 203122:SDE_RS11195
uniprot id: Q21IT4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial histone-like protein family.
messages: Heterodimer of an alpha and a beta chain.
messages: This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.

203122:SDE RS03640
gene id: 203122:SDE_RS03640
uniprot id: Q21MY4
names: Similarity
messages: Belongs to the glycosyl hydrolase 53 family.

203122:SDE RS04435
gene id: 203122:SDE_RS04435
uniprot id: Q21MH7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

203122:SDE RS10625
gene id: 203122:SDE_RS10625
uniprot id: Q21J45
names: Similarity
messages: Belongs to the transglycosylase Slt family.

203122:SDE RS03550
gene id: 203122:SDE_RS03550
uniprot id: Q21N02
names: Similarity
messages: Belongs to the Dps family.

203122:SDE RS04285
gene id: 203122:SDE_RS04285
uniprot id: Q21MK7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. PrmA family.
messages: Cytoplasm
messages: Methylates ribosomal protein L11.

203122:SDE RS11030
gene id: 203122:SDE_RS11030
uniprot id: Q21IW7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

203122:SDE RS11540
gene id: 203122:SDE_RS11540
uniprot id: Q21IL5
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the flagella basal body rod proteins family.
messages: Secreted

203122:SDE RS19565
gene id: 203122:SDE_RS19565
uniprot id: Q21E79
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

203122:SDE RS00725
gene id: 203122:SDE_RS00725
uniprot id: Q21PH5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

203122:SDE RS16040
gene id: 203122:SDE_RS16040
uniprot id: Q21G60
names: Similarity
messages: Belongs to the YkuD family.

203122:SDE RS04740
gene id: 203122:SDE_RS04740
uniprot id: Q21MB6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0761 family.
messages: Cell inner membrane

203122:SDE RS10460
gene id: 203122:SDE_RS10460
uniprot id: Q21J78
names: Function
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.
messages: Catalyzes the isomerization of citrate to isocitrate via cis-aconitate.

203122:SDE RS10635
gene id: 203122:SDE_RS10635
uniprot id: Q21J43
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

203122:SDE RS02650
gene id: 203122:SDE_RS02650
uniprot id: Q21NH8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

203122:SDE RS06645
gene id: 203122:SDE_RS06645
uniprot id: Q21LA0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

203122:SDE RS06245
gene id: 203122:SDE_RS06245
uniprot id: Q21LI0
names: Similarity
messages: Belongs to the aldose epimerase family.

203122:SDE RS08080
gene id: 203122:SDE_RS08080
uniprot id: Q21KH5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the type IA topoisomerase family.
messages: Binds two Mg(2+) per subunit.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

203122:SDE RS19590
gene id: 203122:SDE_RS19590
uniprot id: Q21E74
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

203122:SDE RS16700
gene id: 203122:SDE_RS16700
uniprot id: Q21FT2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MreD family.
messages: Cell inner membrane
messages: Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins.
messages: Membrane

203122:SDE RS20565
gene id: 203122:SDE_RS20565
uniprot id: Q21DN9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

203122:SDE RS07705
gene id: 203122:SDE_RS07705
uniprot id: Q21KP6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Catalyzes the last two steps in the biosynthesis of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the DAO family.
messages: In the N-terminal section; belongs to the methyltransferase superfamily. tRNA (mnm(5)s(2)U34)-methyltransferase family.

203122:SDE RS15455
gene id: 203122:SDE_RS15455
uniprot id: Q21GG7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

203122:SDE RS11970
gene id: 203122:SDE_RS11970
uniprot id: Q21ID0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

203122:SDE RS11610
gene id: 203122:SDE_RS11610
uniprot id: Q21IK1
names: Function
names: Similarity
messages: Belongs to the FlgN family.
messages: Required for the efficient initiation of filament assembly.

203122:SDE RS03850
gene id: 203122:SDE_RS03850
uniprot id: Q21MU4
names: Function
names: Similarity
messages: Belongs to the DHNA family.
messages: Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin.

203122:SDE RS06840
gene id: 203122:SDE_RS06840
uniprot id: Q21L63
names: Function
names: Similarity
messages: Belongs to the Dus family. DusC subfamily.
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U16 in tRNAs.

203122:SDE RS07410
gene id: 203122:SDE_RS07410
uniprot id: Q21KV3
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

203122:SDE RS12330
gene id: 203122:SDE_RS12330
uniprot id: Q21I66
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. NasA/NapA/NarB subfamily.

203122:SDE RS08480
gene id: 203122:SDE_RS08480
uniprot id: Q21K99
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

203122:SDE RS14650
gene id: 203122:SDE_RS14650
uniprot id: Q21GX4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

203122:SDE RS16270
gene id: 203122:SDE_RS16270
uniprot id: Q21G17
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

203122:SDE RS00385
gene id: 203122:SDE_RS00385
uniprot id: Q21PP0
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

203122:SDE RS10800
gene id: 203122:SDE_RS10800
uniprot id: Q21J12
names: Similarity
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.

203122:SDE RS06485
gene id: 203122:SDE_RS06485
uniprot id: Q21LD2
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family. GreB subfamily.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length.

203122:SDE RS05390
gene id: 203122:SDE_RS05390
uniprot id: Q21LZ2
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 67 family.
messages: Homodimer.

203122:SDE RS19580
gene id: 203122:SDE_RS19580
uniprot id: Q21E76
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

203122:SDE RS19100
gene id: 203122:SDE_RS19100
uniprot id: Q21EG8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.

203122:SDE RS06990
gene id: 203122:SDE_RS06990
uniprot id: Q21L34
names: Function
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

203122:SDE RS08840
gene id: 203122:SDE_RS08840
uniprot id: Q21K29
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the R-transferase family. Bpt subfamily.
messages: Cytoplasm
messages: Functions in the N-end rule pathway of protein degradation where it conjugates Leu from its aminoacyl-tRNA to the N-termini of proteins containing an N-terminal aspartate or glutamate.

203122:SDE RS13400
gene id: 203122:SDE_RS13400
uniprot id: Q21HL3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP H family.
messages: Cell inner membrane
messages: Membrane

203122:SDE RS00215
gene id: 203122:SDE_RS00215
uniprot id: Q21PS4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SURF1 family.
messages: Cell membrane

203122:SDE RS18475
gene id: 203122:SDE_RS18475
uniprot id: Q21EU1
names: Similarity
messages: Belongs to the band 7/mec-2 family.

203122:SDE RS14670
gene id: 203122:SDE_RS14670
uniprot id: Q21GX0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)- to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Homodimer.

203122:SDE RS13605
gene id: 203122:SDE_RS13605
uniprot id: Q21HH2
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

203122:SDE RS16900
gene id: 203122:SDE_RS16900
uniprot id: Q21FP1
names: Similarity
messages: Belongs to the DODA-type extradiol aromatic ring-opening dioxygenase family.

203122:SDE RS17360
gene id: 203122:SDE_RS17360
uniprot id: Q21FF7
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

203122:SDE RS14095
gene id: 203122:SDE_RS14095
uniprot id: Q21H75
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.

203122:SDE RS01175
gene id: 203122:SDE_RS01175
uniprot id: Q21P95
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the urease beta subunit family.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

203122:SDE RS17090
gene id: 203122:SDE_RS17090
uniprot id: Q21FK9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

203122:SDE RS01790
gene id: 203122:SDE_RS01790
uniprot id: Q21NX8
names: Cofactor
names: Function
names: Similarity
messages: Adenine glycosylase active on G-A mispairs. MutY also corrects error-prone DNA synthesis past GO lesions which are due to the oxidatively damaged form of guanine: 7,8-dihydro-8-oxoguanine (8-oxo-dGTP).
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.

203122:SDE RS21400
gene id: 203122:SDE_RS21400
uniprot id: Q21H68
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiJ family.
messages: Cytoplasm
messages: Required for ubiquinone (coenzyme Q) biosynthesis. Binds hydrophobic ubiquinone biosynthetic intermediates via its SCP2 domain and is essential for the stability of the Ubi complex. May constitute a docking platform where Ubi enzymes assemble and access their SCP2-bound polyprenyl substrates.

203122:SDE RS05175
gene id: 203122:SDE_RS05175
uniprot id: Q21M34
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

203122:SDE RS05790
gene id: 203122:SDE_RS05790
uniprot id: Q21LR6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

203122:SDE RS21095
gene id: 203122:SDE_RS21095
uniprot id: Q21NE5
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

203122:SDE RS09935
gene id: 203122:SDE_RS09935
uniprot id: Q21JH8
names: Function
names: Similarity
messages: Belongs to the mannonate dehydratase family.
messages: Catalyzes the dehydration of D-mannonate.

203122:SDE RS20045
gene id: 203122:SDE_RS20045
uniprot id: Q21DY7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family.
messages: Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate.
messages: Cell inner membrane

203122:SDE RS13335
gene id: 203122:SDE_RS13335
uniprot id: Q21HM6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

203122:SDE RS09415
gene id: 203122:SDE_RS09415
uniprot id: Q21JR8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell inner membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

203122:SDE RS20675
gene id: 203122:SDE_RS20675
uniprot id: Q21DL9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

203122:SDE RS03730
gene id: 203122:SDE_RS03730
uniprot id: Q21MW6
names: Similarity
messages: Belongs to the glycosyl hydrolase 11 (cellulase G) family.

203122:SDE RS04505
gene id: 203122:SDE_RS04505
uniprot id: Q21MG3
names: Function
names: Similarity
messages: Belongs to the LpxC family.
messages: Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.

203122:SDE RS06150
gene id: 203122:SDE_RS06150
uniprot id: Q21LJ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell inner membrane
messages: Membrane

203122:SDE RS04545
gene id: 203122:SDE_RS04545
uniprot id: Q21MF5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Cell inner membrane
messages: Membrane

203122:SDE RS14900
gene id: 203122:SDE_RS14900
uniprot id: Q21GS5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. Molybdate importer (TC 3.A.1.8) family.
messages: Cell inner membrane
messages: Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system.
messages: The complex is composed of two ATP-binding proteins (ModC), two transmembrane proteins (ModB) and a solute-binding protein (ModA).

203122:SDE RS11915
gene id: 203122:SDE_RS11915
uniprot id: Q21IE1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Nitrate/nitrite porter (TC 2.A.1.8) family.
messages: Membrane

203122:SDE RS05115
gene id: 203122:SDE_RS05115
uniprot id: Q21M48
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

203122:SDE RS09020
gene id: 203122:SDE_RS09020
uniprot id: Q21JZ5
names: Function
names: Similarity
messages: Belongs to the flavodoxin family.
messages: Low-potential electron donor to a number of redox enzymes.

203122:SDE RS03965
gene id: 203122:SDE_RS03965
uniprot id: Q21MS1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

203122:SDE RS05055
gene id: 203122:SDE_RS05055
uniprot id: Q21M59
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PNT beta subunit family.
messages: Cell inner membrane
messages: Heterodimer of an alpha and a beta chain.
messages: Membrane
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

203122:SDE RS08125
gene id: 203122:SDE_RS08125
uniprot id: Q21KG6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

203122:SDE RS05045
gene id: 203122:SDE_RS05045
uniprot id: Q21M61
names: Similarity
messages: Belongs to the AlaDH/PNT family.

203122:SDE RS10030
gene id: 203122:SDE_RS10030
uniprot id: Q21JG0
names: Subcellular Location Annotation
messages: Cytoplasm

203122:SDE RS17720
gene id: 203122:SDE_RS17720
uniprot id: Q21F86
names: Function
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

203122:SDE RS18690
gene id: 203122:SDE_RS18690
uniprot id: Q21EP8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP H family.
messages: Cell inner membrane
messages: Membrane

203122:SDE RS15840
gene id: 203122:SDE_RS15840
uniprot id: Q21G98
names: Subcellular Location Annotation
messages: Membrane

203122:SDE RS14060
gene id: 203122:SDE_RS14060
uniprot id: Q21H82
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial secretin family. PilQ subfamily.
messages: Cell outer membrane
messages: Membrane

203122:SDE RS04005
gene id: 203122:SDE_RS04005
uniprot id: Q21MR3
names: Similarity
messages: Belongs to the TrpC family.

203122:SDE RS06815
gene id: 203122:SDE_RS06815
uniprot id: Q21L66
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Mediates global changes in gene expression, shifting from rapid growth to stress survival by linking envelope stress, the stringent response and the catabolite repression systems. Usually binds in the 5'-UTR; binding at or near the Shine-Dalgarno sequence prevents ribosome-binding, repressing translation, binding elsewhere in the 5'-UTR can activate translation and/or stabilize the mRNA. Its function is antagonized by small RNA(s).
messages: Belongs to the CsrA/RsmA family.
messages: Cytoplasm
messages: Homodimer; the beta-strands of each monomer intercalate to form a hydrophobic core, while the alpha-helices form wings that extend away from the core.

203122:SDE RS01975
gene id: 203122:SDE_RS01975
uniprot id: Q21NU1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family. ParE type 1 subfamily.
messages: Heterotetramer composed of ParC and ParE.
messages: Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.

203122:SDE RS12545
gene id: 203122:SDE_RS12545
uniprot id: Q21I23
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dCTP deaminase family.
messages: Catalyzes the deamination of dCTP to dUTP.
messages: Homotrimer.

203122:SDE RS08600
gene id: 203122:SDE_RS08600
uniprot id: Q21K77
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

203122:SDE RS10265
gene id: 203122:SDE_RS10265
uniprot id: Q21JB7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

203122:SDE RS01855
gene id: 203122:SDE_RS01855
uniprot id: Q21NW5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

203122:SDE RS20440
gene id: 203122:SDE_RS20440
uniprot id: Q21DR4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

203122:SDE RS02705
gene id: 203122:SDE_RS02705
uniprot id: Q21NG8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecB family.
messages: Cytoplasm
messages: Homotetramer, a dimer of dimers. One homotetramer interacts with 1 SecA dimer.
messages: One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA.

203122:SDE RS13540
gene id: 203122:SDE_RS13540
uniprot id: Q21HI5
names: Function
names: Similarity
messages: Belongs to the LpxB family.
messages: Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

203122:SDE RS07520
gene id: 203122:SDE_RS07520
uniprot id: Q21KT1
names: Similarity
messages: Belongs to the YfgM family.

203122:SDE RS04790
gene id: 203122:SDE_RS04790
uniprot id: Q21MA6
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

203122:SDE RS21545
gene id: 203122:SDE_RS21545
uniprot id: Q21FP7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatB family.
messages: Cell inner membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

203122:SDE RS02055
gene id: 203122:SDE_RS02055
uniprot id: Q21NS5
names: Subcellular Location Annotation
messages: Membrane

203122:SDE RS18085
gene id: 203122:SDE_RS18085
uniprot id: Q21F16
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion.
messages: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.
messages: In the C-terminal section; belongs to the HTP reductase family.
messages: In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family.

203122:SDE RS17000
gene id: 203122:SDE_RS17000
uniprot id: Q21FM5
names: Subcellular Location Annotation
messages: Secreted

203122:SDE RS20755
gene id: 203122:SDE_RS20755
uniprot id: Q21DK3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase C chain family.
messages: Cell inner membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Membrane

203122:SDE RS11095
gene id: 203122:SDE_RS11095
uniprot id: Q21IV4
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

203122:SDE RS17365
gene id: 203122:SDE_RS17365
uniprot id: Q21FF6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

203122:SDE RS05030
gene id: 203122:SDE_RS05030
uniprot id: Q21M64
names: Similarity
messages: Belongs to the glycosyl hydrolase 28 family.

203122:SDE RS10605
gene id: 203122:SDE_RS10605
uniprot id: Q21J49
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NhaB Na(+)/H(+) (TC 2.A.34) antiporter family.
messages: Cell inner membrane
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

203122:SDE RS20570
gene id: 203122:SDE_RS20570
uniprot id: Q21DN8
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

203122:SDE RS20555
gene id: 203122:SDE_RS20555
uniprot id: Q21DP1
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

203122:SDE RS08800
gene id: 203122:SDE_RS08800
uniprot id: Q21K37
names: Similarity
names: Subunit
messages: Belongs to the Nudix hydrolase family. NudJ subfamily.
messages: Monomer.

203122:SDE RS16465
gene id: 203122:SDE_RS16465
uniprot id: Q21FX8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

203122:SDE RS04270
gene id: 203122:SDE_RS04270
uniprot id: Q21ML0
names: Similarity
messages: Belongs to the transcriptional regulatory Fis family.

203122:SDE RS06040
gene id: 203122:SDE_RS06040
uniprot id: Q21LL6
names: Similarity
messages: Belongs to the UPF0270 family.

203122:SDE RS02765
gene id: 203122:SDE_RS02765
uniprot id: Q21NF6
names: Similarity
messages: Belongs to the glycosyl hydrolase 5 (cellulase A) family.

203122:SDE RS13260
gene id: 203122:SDE_RS13260
uniprot id: Q21HN6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvB family.
messages: Cytoplasm
messages: Has 3 domains, the large (RuvB-L) and small ATPase (RuvB-S) domains and the C-terminal head (RuvB-H) domain. The head domain binds DNA, while the ATPase domains jointly bind ATP, ADP or are empty depending on the state of the subunit in the translocation cycle. During a single DNA translocation step the structure of each domain remains the same, but their relative positions change.
messages: Homohexamer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time. Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange. Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration. The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration. Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.

203122:SDE RS08835
gene id: 203122:SDE_RS08835
uniprot id: Q21K30
names: Similarity
messages: Belongs to the peptidase M16 family.

203122:SDE RS12770
gene id: 203122:SDE_RS12770
uniprot id: Q21HX9
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: May also have succinyldiaminopimelate aminotransferase activity, thus carrying out the corresponding step in lysine biosynthesis.

203122:SDE RS14170
gene id: 203122:SDE_RS14170
uniprot id: Q21H60
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

203122:SDE RS17480
gene id: 203122:SDE_RS17480
uniprot id: Q21FD3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transpeptidase family. MrdA subfamily.
messages: Catalyzes cross-linking of the peptidoglycan cell wall.
messages: Cell inner membrane

203122:SDE RS13450
gene id: 203122:SDE_RS13450
uniprot id: Q21HK3
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

203122:SDE RS17560
gene id: 203122:SDE_RS17560
uniprot id: Q21FB7
names: Subcellular Location Annotation
messages: Membrane

203122:SDE RS14790
gene id: 203122:SDE_RS14790
uniprot id: Q21GU6
names: Subcellular Location Annotation
messages: Membrane

203122:SDE RS13650
gene id: 203122:SDE_RS13650
uniprot id: Q21HG3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type 2 tetrahydrodipicolinate N-succinyltransferase family.
messages: Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2-amino-6-oxopimelate using succinyl-CoA.
messages: Cytoplasm
messages: Homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

203122:SDE RS05070
gene id: 203122:SDE_RS05070
uniprot id: Q21M56
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

203122:SDE RS08540
gene id: 203122:SDE_RS08540
uniprot id: Q21K88
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

203122:SDE RS07000
gene id: 203122:SDE_RS07000
uniprot id: Q21L32
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

203122:SDE RS08495
gene id: 203122:SDE_RS08495
uniprot id: Q21K97
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

203122:SDE RS06680
gene id: 203122:SDE_RS06680
uniprot id: Q21L93
names: Similarity
messages: Belongs to the AlaDH/PNT family.

203122:SDE RS10610
gene id: 203122:SDE_RS10610
uniprot id: Q21J48
names: Function
names: Subunit
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease.

203122:SDE RS11785
gene id: 203122:SDE_RS11785
uniprot id: Q21IG7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily.
messages: Catalyzes the oxidation of L-aspartate to iminoaspartate.
messages: Cytoplasm

203122:SDE RS13655
gene id: 203122:SDE_RS13655
uniprot id: Q21HG2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M20A family. DapE subfamily.
messages: Binds 2 Zn(2+) or Co(2+) ions per subunit.
messages: Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls.
messages: Homodimer.

203122:SDE RS08285
gene id: 203122:SDE_RS08285
uniprot id: Q21KD6
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

203122:SDE RS18945
gene id: 203122:SDE_RS18945
uniprot id: Q21EJ8
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HSP33 family.
messages: Cytoplasm
messages: Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress.
messages: Under oxidizing conditions two disulfide bonds are formed involving the reactive cysteines. Under reducing conditions zinc is bound to the reactive cysteines and the protein is inactive.

203122:SDE RS11100
gene id: 203122:SDE_RS11100
uniprot id: Q21IV3
names: Function
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. Fucose synthase subfamily.
messages: Catalyzes the two-step NADP-dependent conversion of GDP-4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction.

203122:SDE RS15910
gene id: 203122:SDE_RS15910
uniprot id: Q7PC49
names: Similarity
messages: Belongs to the glycosyl hydrolase 20 family.

203122:SDE RS04535
gene id: 203122:SDE_RS04535
uniprot id: Q21MF7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

203122:SDE RS20905
gene id: 203122:SDE_RS20905
uniprot id: Q21DH4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

203122:SDE RS19595
gene id: 203122:SDE_RS19595
uniprot id: Q21E73
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

203122:SDE RS06535
gene id: 203122:SDE_RS06535
uniprot id: Q21LC2
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Component of the RNA degradosome, which is a multiprotein complex involved in RNA processing and mRNA degradation.
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

203122:SDE RS06360
gene id: 203122:SDE_RS06360
uniprot id: Q21LF7
names: Similarity
messages: Belongs to the threonine synthase family.

203122:SDE RS11570
gene id: 203122:SDE_RS11570
uniprot id: Q21IK9
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.

203122:SDE RS09345
gene id: 203122:SDE_RS09345
uniprot id: Q21JT2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S24 family.
messages: Homodimer.
messages: Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.

203122:SDE RS03690
gene id: 203122:SDE_RS03690
uniprot id: Q21MX4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

203122:SDE RS08815
gene id: 203122:SDE_RS08815
uniprot id: Q21K34
names: Subcellular Location Annotation
messages: Cytoplasm

203122:SDE RS05405
gene id: 203122:SDE_RS05405
uniprot id: Q21LY9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-C family. DnaE2 subfamily.
messages: Cytoplasm
messages: DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase.

203122:SDE RS12860
gene id: 203122:SDE_RS12860
uniprot id: Q21HW1
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

203122:SDE RS05820
gene id: 203122:SDE_RS05820
uniprot id: Q21LR0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccA family.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

203122:SDE RS07815
gene id: 203122:SDE_RS07815
uniprot id: Q21KM4
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

203122:SDE RS03030
gene id: 203122:SDE_RS03030
uniprot id: Q21NA5
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

203122:SDE RS14155
gene id: 203122:SDE_RS14155
uniprot id: Q21H63
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

203122:SDE RS13075
gene id: 203122:SDE_RS13075
uniprot id: Q21HR9
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.

203122:SDE RS02040
gene id: 203122:SDE_RS02040
uniprot id: Q21NS8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. Lipid exporter (TC 3.A.1.106) family.
messages: Cell inner membrane
messages: Homodimer.
messages: In MsbA the ATP-binding domain (NBD) and the transmembrane domain (TMD) are fused.
messages: Involved in lipopolysaccharide (LPS) biosynthesis. Translocates lipid A-core from the inner to the outer leaflet of the inner membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation.

203122:SDE RS16695
gene id: 203122:SDE_RS16695
uniprot id: Q21FT3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YhdE subfamily.
messages: Cytoplasm
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

203122:SDE RS09690
gene id: 203122:SDE_RS09690
uniprot id: Q21JM4
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

203122:SDE RS17325
gene id: 203122:SDE_RS17325
uniprot id: Q21FG4
names: Similarity
messages: Belongs to the DNA polymerase HolA subunit family.

203122:SDE RS06395
gene id: 203122:SDE_RS06395
uniprot id: Q21LF0
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

203122:SDE RS11585
gene id: 203122:SDE_RS11585
uniprot id: Q21IK6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of a number of rings mounted on a central rod.

203122:SDE RS10940
gene id: 203122:SDE_RS10940
uniprot id: Q21IY5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.

203122:SDE RS11505
gene id: 203122:SDE_RS11505
uniprot id: Q21IM2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliS family.
messages: cytosol

203122:SDE RS18915
gene id: 203122:SDE_RS18915
uniprot id: Q21EK4
names: Similarity
messages: Belongs to the methyltransferase superfamily. Arsenite methyltransferase family.

203122:SDE RS11650
gene id: 203122:SDE_RS11650
uniprot id: Q21IJ4
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TtcA family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is chelated by three Cys residues, the fourth Fe has a free coordination site that may bind a sulfur atom transferred from the persulfide of IscS.
messages: Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system.
messages: Cytoplasm
messages: Homodimer.
messages: The thiolation reaction likely consists of two steps: a first activation step by ATP to form an adenylated intermediate of the target base of tRNA, and a second nucleophilic substitution step of the sulfur (S) atom supplied by the hydrosulfide attached to the Fe-S cluster.

203122:SDE RS18035
gene id: 203122:SDE_RS18035
uniprot id: Q21F26
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polysaccharide lyase 1 family.
messages: Secreted

203122:SDE RS08415
gene id: 203122:SDE_RS08415
uniprot id: Q21KB1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. Thiolase family.
messages: Catalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed.
messages: Cytoplasm
messages: Heterotetramer of two alpha chains (FadB) and two beta chains (FadA).

203122:SDE RS12995
gene id: 203122:SDE_RS12995
uniprot id: Q21HT4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

203122:SDE RS14720
gene id: 203122:SDE_RS14720
uniprot id: Q21GW0
names: Cofactor
messages: Binds 1 Fe(2+) ion per subunit.

203122:SDE RS08355
gene id: 203122:SDE_RS08355
uniprot id: Q21KC3
names: Function
names: Similarity
messages: Belongs to the nucleoside phosphorylase PpnP family.
messages: Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions.

203122:SDE RS03515
gene id: 203122:SDE_RS03515
uniprot id: Q21N09
names: Similarity
messages: Belongs to the ferredoxin--NADP reductase type 1 family.

203122:SDE RS11310
gene id: 203122:SDE_RS11310
uniprot id: Q21IR1
names: Similarity
messages: Belongs to the MotB family.

203122:SDE RS10665
gene id: 203122:SDE_RS10665
uniprot id: Q21J37
names: Cofactor
names: Similarity
messages: Belongs to the RimK family.
messages: Binds 2 magnesium or manganese ions per subunit.

203122:SDE RS02145
gene id: 203122:SDE_RS02145
uniprot id: Q21NQ7
names: Function
names: Subunit
messages: Binds the second messenger bis-(3'-5') cyclic dimeric guanosine monophosphate (c-di-GMP). Can bind two c-di-GMP molecules per monomer. May play a role in bacterial second-messenger regulated processes. Binding to c-di-GMP induces a conformational change of the C- and N-termini resulting in the exposure of a highly negative surface on one side of the protein to a possible effector protein.
messages: Monomer in both c-di-GMP-bound and free forms.

203122:SDE RS19205
gene id: 203122:SDE_RS19205
uniprot id: Q21EE8
names: Similarity
messages: Belongs to the phosphohexose mutase family.

203122:SDE RS11380
gene id: 203122:SDE_RS11380
uniprot id: Q21IP8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliQ/MopD/SpaQ family.
messages: Membrane

203122:SDE RS09115
gene id: 203122:SDE_RS09115
uniprot id: Q21JX8
names: Subcellular Location Annotation
messages: Membrane

203122:SDE RS01895
gene id: 203122:SDE_RS01895
uniprot id: Q21NV7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.

203122:SDE RS16715
gene id: 203122:SDE_RS16715
uniprot id: Q21FS9
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

203122:SDE RS03150
gene id: 203122:SDE_RS03150
uniprot id: Q21N79
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

203122:SDE RS04730
gene id: 203122:SDE_RS04730
uniprot id: Q21MB8
names: Similarity
messages: Belongs to the WrbA family.

203122:SDE RS13180
gene id: 203122:SDE_RS13180
uniprot id: Q21HQ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
messages: Cytoplasm
messages: Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.

203122:SDE RS19425
gene id: 203122:SDE_RS19425
uniprot id: Q21EA6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

203122:SDE RS13575
gene id: 203122:SDE_RS13575
uniprot id: Q21HH8
names: Function
names: Similarity
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).

203122:SDE RS16360
gene id: 203122:SDE_RS16360
uniprot id: Q21FZ9
names: Similarity
messages: Belongs to the acylphosphatase family.

203122:SDE RS14020
gene id: 203122:SDE_RS14020
uniprot id: Q21H90
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Prokaryotic type I sub-subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
messages: Cell membrane
messages: Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The autoendoproteolytic cleavage occurs by a canonical serine protease mechanism, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain. During this reaction, the Ser that is part of the protease active site of the proenzyme becomes the pyruvoyl prosthetic group, which constitutes an essential element of the active site of the mature decarboxylase.

203122:SDE RS19105
gene id: 203122:SDE_RS19105
uniprot id: Q21EG7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UbiD family.
messages: Binds 1 prenylated FMN (prenyl-FMN) per subunit.
messages: Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis.
messages: Cell membrane
messages: Homohexamer.

203122:SDE RS04415
gene id: 203122:SDE_RS04415
uniprot id: Q21MI1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HesB/IscA family.
messages: Binds 1 iron-sulfur cluster per subunit.
messages: Homodimer.
messages: Required for insertion of 4Fe-4S clusters for at least IspG.

203122:SDE RS10180
gene id: 203122:SDE_RS10180
uniprot id: Q21JD4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

203122:SDE RS07680
gene id: 203122:SDE_RS07680
uniprot id: Q21KQ1
names: Caution
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 2 residues (Tyr-59 and Arg-62) present in a large hydrophobic pocket are probably involved in substrate specificity. They are important for desuccinylation activity, but dispensable for deacetylation activity.
messages: Belongs to the sirtuin family. Class III subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form.

203122:SDE RS06695
gene id: 203122:SDE_RS06695
uniprot id: Q21L90
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class II fructose-bisphosphate aldolase family.
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.
messages: Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.

203122:SDE RS19405
gene id: 203122:SDE_RS19405
uniprot id: Q21EB0
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

203122:SDE RS19620
gene id: 203122:SDE_RS19620
uniprot id: Q21E68
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

203122:SDE RS14030
gene id: 203122:SDE_RS14030
uniprot id: Q21H88
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the uroporphyrinogen decarboxylase family.
messages: Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
messages: Cytoplasm
messages: Homodimer.

203122:SDE RS05270
gene id: 203122:SDE_RS05270
uniprot id: Q21M16
names: Similarity
messages: Belongs to the phosphohexose mutase family.

203122:SDE RS15465
gene id: 203122:SDE_RS15465
uniprot id: Q21GG5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

203122:SDE RS14830
gene id: 203122:SDE_RS14830
uniprot id: Q21GT8
names: Similarity
messages: Belongs to the glycosyl hydrolase 81 family.

203122:SDE RS09800
gene id: 203122:SDE_RS09800
uniprot id: Q21JK2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmB/CycW/HelB family.
messages: Cell inner membrane
messages: Membrane
messages: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.

203122:SDE RS13600
gene id: 203122:SDE_RS13600
uniprot id: Q21HH3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

203122:SDE RS16600
gene id: 203122:SDE_RS16600
uniprot id: Q21FV2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm

203122:SDE RS03480
gene id: 203122:SDE_RS03480
uniprot id: Q21N16
names: Subcellular Location Annotation
messages: Membrane

203122:SDE RS07550
gene id: 203122:SDE_RS07550
uniprot id: Q21KS5
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

203122:SDE RS12100
gene id: 203122:SDE_RS12100
uniprot id: Q21IA3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

203122:SDE RS09870
gene id: 203122:SDE_RS09870
uniprot id: Q21JJ0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.

203122:SDE RS03400
gene id: 203122:SDE_RS03400
uniprot id: Q21N32
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 6-phosphogluconate dehydrogenase family.
messages: Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
messages: Homodimer.

203122:SDE RS11045
gene id: 203122:SDE_RS11045
uniprot id: Q21IW4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 1 lipoyl cofactor covalently.
messages: E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).

203122:SDE RS05655
gene id: 203122:SDE_RS05655
uniprot id: Q21LT8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

203122:SDE RS14310
gene id: 203122:SDE_RS14310
uniprot id: Q21H35
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

203122:SDE RS10975
gene id: 203122:SDE_RS10975
uniprot id: Q21IX8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Reduced FMN (FMNH(2)).

203122:SDE RS09675
gene id: 203122:SDE_RS09675
uniprot id: Q21JM7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DoxX family.
messages: Membrane

203122:SDE RS21435
gene id: 203122:SDE_RS21435
uniprot id: Q21GR4
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

203122:SDE RS06685
gene id: 203122:SDE_RS06685
uniprot id: Q21L92
names: Function
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

203122:SDE RS20055
gene id: 203122:SDE_RS20055
uniprot id: Q21DY5
names: Function
messages: Member of the two-component regulatory system PhoR/PhoB involved in the phosphate regulon genes expression. PhoR may function as a membrane-associated protein kinase that phosphorylates PhoB in response to environmental signals.

203122:SDE RS10905
gene id: 203122:SDE_RS10905
uniprot id: Q21IZ2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccD/PCCB family.
messages: Binds 1 zinc ion per subunit.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

203122:SDE RS06945
gene id: 203122:SDE_RS06945
uniprot id: Q21L43
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

203122:SDE RS02810
gene id: 203122:SDE_RS02810
uniprot id: Q21NE7
names: Similarity
messages: Belongs to the oxygen-dependent FAD-linked oxidoreductase family.

203122:SDE RS15640
gene id: 203122:SDE_RS15640
uniprot id: Q21GD1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

203122:SDE RS05450
gene id: 203122:SDE_RS05450
uniprot id: Q21LX9
names: Similarity
messages: Belongs to the myoviridae tail sheath protein family.

203122:SDE RS15550
gene id: 203122:SDE_RS15550
uniprot id: Q21GE8
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

203122:SDE RS07495
gene id: 203122:SDE_RS07495
uniprot id: Q21KT6
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity.

203122:SDE RS16875
gene id: 203122:SDE_RS16875
uniprot id: Q21FP6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

203122:SDE RS02760
gene id: 203122:SDE_RS02760
uniprot id: Q21NF7
names: Function
names: Similarity
messages: Belongs to the N-acylglucosamine 2-epimerase family.
messages: Belongs to the cellobiose 2-epimerase family.
messages: Catalyzes the reversible epimerization of cellobiose to 4-O-beta-D-glucopyranosyl-D-mannose (Glc-Man).

203122:SDE RS12620
gene id: 203122:SDE_RS12620
uniprot id: Q21I08
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.

203122:SDE RS10775
gene id: 203122:SDE_RS10775
uniprot id: Q21J17
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

203122:SDE RS02985
gene id: 203122:SDE_RS02985
uniprot id: Q21NB3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S33 family.
messages: Cytoplasm

203122:SDE RS05975
gene id: 203122:SDE_RS05975
uniprot id: Q21LM9
names: Similarity
messages: Belongs to the GSP E family.

203122:SDE RS17495
gene id: 203122:SDE_RS17495
uniprot id: Q21FD0
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

203122:SDE RS04480
gene id: 203122:SDE_RS04480
uniprot id: Q21MG8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

203122:SDE RS06265
gene id: 203122:SDE_RS06265
uniprot id: Q21LH6
names: Function
names: Similarity
messages: Belongs to the ectoine synthase family.
messages: Catalyzes the circularization of gamma-N-acetyl-alpha,gamma-diaminobutyric acid (ADABA) to ectoine (1,4,5,6-tetrahydro-2-methyl-4-pyrimidine carboxylic acid), which is an excellent osmoprotectant.

203122:SDE RS04880
gene id: 203122:SDE_RS04880
uniprot id: Q21M93
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

203122:SDE RS19475
gene id: 203122:SDE_RS19475
uniprot id: Q21E97
names: Subcellular Location Annotation
messages: Membrane

203122:SDE RS01925
gene id: 203122:SDE_RS01925
uniprot id: Q21NV1
names: Similarity
messages: Belongs to the GSP E family.

203122:SDE RS10105
gene id: 203122:SDE_RS10105
uniprot id: Q21JE8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Cell inner membrane
messages: Homoheptamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mechanosensitive channel that participates in the regulation of osmotic pressure changes within the cell, opening in response to stretch forces in the membrane lipid bilayer, without the need for other proteins. Contributes to normal resistance to hypoosmotic shock. Forms an ion channel of 1.0 nanosiemens conductance with a slight preference for anions.

203122:SDE RS04440
gene id: 203122:SDE_RS04440
uniprot id: Q21MH6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsL family.
messages: Cell inner membrane
messages: Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.
messages: Membrane
messages: Part of a complex composed of FtsB, FtsL and FtsQ.

203122:SDE RS07775
gene id: 203122:SDE_RS07775
uniprot id: Q21KN2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 1 subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

203122:SDE RS17710
gene id: 203122:SDE_RS17710
uniprot id: Q21F88
names: Function
names: Similarity
names: Subunit
messages: Belongs to the serine/threonine dehydratase family.
messages: Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.
messages: Homotetramer.

203122:SDE RS10950
gene id: 203122:SDE_RS10950
uniprot id: Q21IY3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

203122:SDE RS02755
gene id: 203122:SDE_RS02755
uniprot id: Q21NF8
names: Function
names: Similarity
messages: Belongs to the glycosyl hydrolase 130 family.
messages: Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man-Glc) to mannose 1-phosphate (Man1P) and glucose.

203122:SDE RS10540
gene id: 203122:SDE_RS10540
uniprot id: Q21J62
names: Function
names: Similarity
messages: Belongs to the class-I DAHP synthase family.
messages: Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP).

203122:SDE RS06185
gene id: 203122:SDE_RS06185
uniprot id: Q21LJ0
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

203122:SDE RS03510
gene id: 203122:SDE_RS03510
uniprot id: Q21N10
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

203122:SDE RS05650
gene id: 203122:SDE_RS05650
uniprot id: Q21LT9
names: Similarity
messages: Belongs to the N-Me-Phe pilin family.

203122:SDE RS15915
gene id: 203122:SDE_RS15915
uniprot id: Q21G84
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. FHS transporter (TC 2.A.1.7) family.
messages: Cell inner membrane
messages: Intake of glucose and galactose.
messages: Membrane

203122:SDE RS06710
gene id: 203122:SDE_RS06710
uniprot id: Q21L87
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the KduI family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the isomerization of 5-dehydro-4-deoxy-D-glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate.

203122:SDE RS10585
gene id: 203122:SDE_RS10585
uniprot id: Q21J53
names: Similarity
messages: Belongs to the peptidase S49 family.

203122:SDE RS02555
gene id: 203122:SDE_RS02555
uniprot id: Q21NJ7
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

203122:SDE RS07230
gene id: 203122:SDE_RS07230
uniprot id: Q21KY7
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

203122:SDE RS10495
gene id: 203122:SDE_RS10495
uniprot id: Q21J71
names: Similarity
messages: Belongs to the ETF beta-subunit/FixA family.

203122:SDE RS11085
gene id: 203122:SDE_RS11085
uniprot id: Q21IV6
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

203122:SDE RS14090
gene id: 203122:SDE_RS14090
uniprot id: Q21H76
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

203122:SDE RS21310
gene id: 203122:SDE_RS21310
uniprot id: Q21J05
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the N-Me-Phe pilin family.
messages: Membrane

203122:SDE RS13375
gene id: 203122:SDE_RS13375
uniprot id: Q21HL8
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

203122:SDE RS02035
gene id: 203122:SDE_RS02035
uniprot id: Q21NS9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase group 1 family.
messages: Cell membrane
messages: Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP-Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A.

203122:SDE RS06590
gene id: 203122:SDE_RS06590
uniprot id: Q21LB1
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.
messages: This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.

203122:SDE RS05300
gene id: 203122:SDE_RS05300
uniprot id: Q21M10
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

203122:SDE RS08865
gene id: 203122:SDE_RS08865
uniprot id: Q21K24
names: Function
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.
messages: DNA-dependent ATPase that plays important roles in cellular responses to stalled DNA replication processes.

203122:SDE RS19440
gene id: 203122:SDE_RS19440
uniprot id: Q21EA3
names: Similarity
messages: Belongs to the MipA/OmpV family.

203122:SDE RS05135
gene id: 203122:SDE_RS05135
uniprot id: Q21M44
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

203122:SDE RS07175
gene id: 203122:SDE_RS07175
uniprot id: Q21KZ8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

203122:SDE RS08060
gene id: 203122:SDE_RS08060
uniprot id: Q21KH9
names: Similarity
messages: Belongs to the VgrG protein family.

203122:SDE RS19155
gene id: 203122:SDE_RS19155
uniprot id: Q21EF8
names: Function
names: Similarity
messages: Belongs to the uroporphyrinogen-III synthase family.
messages: Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.

203122:SDE RS03930
gene id: 203122:SDE_RS03930
uniprot id: Q21MS8
names: Domain
names: Function
names: Subcellular Location Annotation
messages: Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation.
messages: Periplasm
messages: The PPIase activity resides only in the second parvulin domain. The N-terminal region and the C-terminal tail are necessary and sufficient for the chaperone activity of SurA. The PPIase activity is dispensable for SurA to function as a chaperone. The N-terminal region and the C-terminal tail are also required for porin recognition.

203122:SDE RS16020
gene id: 203122:SDE_RS16020
uniprot id: Q21G63
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

203122:SDE RS03240
gene id: 203122:SDE_RS03240
uniprot id: Q21N61
names: Similarity
messages: Belongs to the UPF0337 (CsbD) family.

203122:SDE RS13985
gene id: 203122:SDE_RS13985
uniprot id: Q21H97
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Belongs to the NnrE/AIBP family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.

203122:SDE RS14280
gene id: 203122:SDE_RS14280
uniprot id: Q21H40
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

203122:SDE RS04385
gene id: 203122:SDE_RS04385
uniprot id: Q21MI7
names: Similarity
messages: Belongs to the catalase family.

203122:SDE RS19990
gene id: 203122:SDE_RS19990
uniprot id: Q21DZ7
names: Similarity
messages: Belongs to the GST superfamily.

203122:SDE RS07830
gene id: 203122:SDE_RS07830
uniprot id: Q21KM1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Monomer.

203122:SDE RS05900
gene id: 203122:SDE_RS05900
uniprot id: Q21LP4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

203122:SDE RS20975
gene id: 203122:SDE_RS20975
uniprot id: Q21DG0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Cell inner membrane
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

203122:SDE RS18780
gene id: 203122:SDE_RS18780
uniprot id: Q21EN0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoH subfamily.
messages: Cytoplasm
messages: Interacts with the RNA polymerase core enzyme.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes.

203122:SDE RS14215
gene id: 203122:SDE_RS14215
uniprot id: Q21H53
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

203122:SDE RS19145
gene id: 203122:SDE_RS19145
uniprot id: Q21EG0
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Involved in a late step of protoheme IX synthesis.
messages: Membrane

203122:SDE RS00840
gene id: 203122:SDE_RS00840
uniprot id: Q21PF2
names: Similarity
messages: Belongs to the PrpF family.

203122:SDE RS10160
gene id: 203122:SDE_RS10160
uniprot id: Q21JD8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

203122:SDE RS19135
gene id: 203122:SDE_RS19135
uniprot id: Q21EG2
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.

203122:SDE RS16280
gene id: 203122:SDE_RS16280
uniprot id: Q21G15
names: Function
messages: Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors. CheA is autophosphorylated; it can transfer its phosphate group to either CheB or CheY.

203122:SDE RS05305
gene id: 203122:SDE_RS05305
uniprot id: Q21M09
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

203122:SDE RS01360
gene id: 203122:SDE_RS01360
uniprot id: Q21P58
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

203122:SDE RS03895
gene id: 203122:SDE_RS03895
uniprot id: Q21MT5
names: Similarity
messages: Belongs to the UPF0229 family.

203122:SDE RS20735
gene id: 203122:SDE_RS20735
uniprot id: Q21DK7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

203122:SDE RS14240
gene id: 203122:SDE_RS14240
uniprot id: Q21H48
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.
messages: Cytoplasm
messages: Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.

203122:SDE RS09275
gene id: 203122:SDE_RS09275
uniprot id: Q21JU6
names: Subcellular Location Annotation
messages: Membrane

203122:SDE RS20935
gene id: 203122:SDE_RS20935
uniprot id: Q21DG8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

203122:SDE RS04490
gene id: 203122:SDE_RS04490
uniprot id: Q21MG6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsQ/DivIB family. FtsQ subfamily.
messages: Cell inner membrane
messages: Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly.
messages: Part of a complex composed of FtsB, FtsL and FtsQ.

203122:SDE RS18380
gene id: 203122:SDE_RS18380
uniprot id: Q21EV8
names: Function
names: Similarity
names: Subunit
messages: Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division.
messages: Belongs to the ZapA family. Type 1 subfamily.
messages: Homodimer. Interacts with FtsZ.

203122:SDE RS11560
gene id: 203122:SDE_RS11560
uniprot id: Q21IL1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

203122:SDE RS08430
gene id: 203122:SDE_RS08430
uniprot id: Q21KA9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

203122:SDE RS16840
gene id: 203122:SDE_RS16840
uniprot id: Q21FQ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MotA family.
messages: Membrane

203122:SDE RS06365
gene id: 203122:SDE_RS06365
uniprot id: Q21LF6
names: Similarity
messages: Belongs to the YkuD family.

203122:SDE RS08870
gene id: 203122:SDE_RS08870
uniprot id: Q21K23
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fluoride channel Fluc/FEX (TC 1.A.43) family.
messages: Cell inner membrane
messages: Fluoride-specific ion channel. Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Na(+) is not transported, but it plays an essential structural role and its presence is essential for fluoride channel function.

203122:SDE RS01020
gene id: 203122:SDE_RS01020
uniprot id: Q21PB8
names: Similarity
messages: Belongs to the XseB family.

203122:SDE RS13145
gene id: 203122:SDE_RS13145
uniprot id: Q21HQ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane
messages: Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins.

203122:SDE RS01575
gene id: 203122:SDE_RS01575
uniprot id: Q21P18
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

203122:SDE RS03910
gene id: 203122:SDE_RS03910
uniprot id: Q21MT2
names: Function
names: Similarity
messages: Belongs to the Ap4A hydrolase family.
messages: Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP.

203122:SDE RS04400
gene id: 203122:SDE_RS04400
uniprot id: Q21MI4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

203122:SDE RS20635
gene id: 203122:SDE_RS20635
uniprot id: Q21DM6
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

203122:SDE RS16440
gene id: 203122:SDE_RS16440
uniprot id: Q21FY3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. Biotin synthase family.
messages: Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
messages: Homodimer.

203122:SDE RS09360
gene id: 203122:SDE_RS09360
uniprot id: Q7PC47
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 3 family. NagZ subfamily.
messages: Cytoplasm
messages: Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide-linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N-acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides.

203122:SDE RS01625
gene id: 203122:SDE_RS01625
uniprot id: Q21P08
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

203122:SDE RS03025
gene id: 203122:SDE_RS03025
uniprot id: Q21NA6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

203122:SDE RS09190
gene id: 203122:SDE_RS09190
uniprot id: Q21JW3
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

203122:SDE RS12590
gene id: 203122:SDE_RS12590
uniprot id: Q21I14
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell inner membrane
messages: Membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

203122:SDE RS07360
gene id: 203122:SDE_RS07360
uniprot id: Q21KW2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

203122:SDE RS18770
gene id: 203122:SDE_RS18770
uniprot id: Q21EN2
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.

203122:SDE RS04180
gene id: 203122:SDE_RS04180
uniprot id: Q21MM8
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

203122:SDE RS07780
gene id: 203122:SDE_RS07780
uniprot id: Q21KN1
names: Function
names: Similarity
messages: Belongs to the Dus family. DusA subfamily.
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U20 and U20a in tRNAs.

203122:SDE RS02775
gene id: 203122:SDE_RS02775
uniprot id: Q21NF4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

203122:SDE RS12730
gene id: 203122:SDE_RS12730
uniprot id: Q21HY7
names: Function
names: Similarity
messages: Belongs to the bacterioferritin family.
messages: Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex.

203122:SDE RS14230
gene id: 203122:SDE_RS14230
uniprot id: Q21H50
names: Function
names: Similarity
messages: Belongs to the DHPS family.
messages: Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives.

203122:SDE RS13910
gene id: 203122:SDE_RS13910
uniprot id: Q21HB2
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

203122:SDE RS15340
gene id: 203122:SDE_RS15340
uniprot id: Q21GI8
names: Similarity
messages: Belongs to the glycosyl hydrolase 10 (cellulase F) family.

203122:SDE RS11575
gene id: 203122:SDE_RS11575
uniprot id: Q21IK8
names: Function
names: Similarity
messages: Belongs to the FlgD family.
messages: Required for flagellar hook formation. May act as a scaffolding protein.

203122:SDE RS06810
gene id: 203122:SDE_RS06810
uniprot id: Q21L67
names: Similarity
messages: Belongs to the aspartokinase family.

203122:SDE RS05165
gene id: 203122:SDE_RS05165
uniprot id: Q21M36
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

203122:SDE RS00425
gene id: 203122:SDE_RS00425
uniprot id: Q21PN2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NapD family.
messages: Chaperone for NapA, the catalytic subunit of the periplasmic nitrate reductase. It binds directly and specifically to the twin-arginine signal peptide of NapA, preventing premature interaction with the Tat translocase and premature export.
messages: Cytoplasm
messages: Interacts with the cytoplasmic NapA precursor.

203122:SDE RS17580
gene id: 203122:SDE_RS17580
uniprot id: Q21FB3
names: Function
names: Similarity
messages: Belongs to the MurCDEF family. Mpl subfamily.
messages: Reutilizes the intact tripeptide L-alanyl-gamma-D-glutamyl-meso-diaminopimelate by linking it to UDP-N-acetylmuramate.

203122:SDE RS21585
gene id: 203122:SDE_RS21585
uniprot id: Q21F80
names: Subcellular Location Annotation
messages: Membrane

203122:SDE RS01950
gene id: 203122:SDE_RS01950
uniprot id: Q21NU6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ThiC family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
messages: Homodimer.

203122:SDE RS07910
gene id: 203122:SDE_RS07910
uniprot id: Q21KK8
names: Similarity
messages: Belongs to the DEAD box helicase family.

203122:SDE RS09980
gene id: 203122:SDE_RS09980
uniprot id: Q21JG9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LpxH family.
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.
messages: Binds 2 Mn(2+) ions per subunit in a binuclear metal center.
messages: Cell inner membrane
messages: Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

203122:SDE RS10515
gene id: 203122:SDE_RS10515
uniprot id: Q21J68
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

203122:SDE RS04805
gene id: 203122:SDE_RS04805
uniprot id: Q21MA3
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

203122:SDE RS18740
gene id: 203122:SDE_RS18740
uniprot id: Q21EN8
names: Similarity
messages: Belongs to the Rsd/AlgQ family.

203122:SDE RS13960
gene id: 203122:SDE_RS13960
uniprot id: Q21HA2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Hfq family.
messages: Homohexamer.
messages: RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs.

203122:SDE RS11680
gene id: 203122:SDE_RS11680
uniprot id: Q21II8
names: Similarity
messages: Belongs to the peptidase M18 family.

203122:SDE RS03835
gene id: 203122:SDE_RS03835
uniprot id: Q21MU7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

203122:SDE RS06350
gene id: 203122:SDE_RS06350
uniprot id: Q21LF9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbC subfamily.
messages: Periplasm
messages: Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process.

203122:SDE RS12565
gene id: 203122:SDE_RS12565
uniprot id: Q21I19
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfB subfamily.
messages: Binds 3 [4Fe-4S] clusters.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

203122:SDE RS04370
gene id: 203122:SDE_RS04370
uniprot id: Q21MJ0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

203122:SDE RS11720
gene id: 203122:SDE_RS11720
uniprot id: Q21II0
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

203122:SDE RS13500
gene id: 203122:SDE_RS13500
uniprot id: Q21HJ3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48 family. BepA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Functions as both a chaperone and a metalloprotease. Maintains the integrity of the outer membrane by promoting either the assembly or the elimination of outer membrane proteins, depending on their folding state.
messages: Periplasm

203122:SDE RS09985
gene id: 203122:SDE_RS09985
uniprot id: Q21JG8
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

203122:SDE RS10700
gene id: 203122:SDE_RS10700
uniprot id: Q21J30
names: Similarity
messages: Belongs to the HipA Ser/Thr kinase family.

203122:SDE RS16895
gene id: 203122:SDE_RS16895
uniprot id: Q21FP2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

203122:SDE RS10945
gene id: 203122:SDE_RS10945
uniprot id: Q21IY4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 1 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

203122:SDE RS06625
gene id: 203122:SDE_RS06625
uniprot id: Q21LA4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

203122:SDE RS20040
gene id: 203122:SDE_RS20040
uniprot id: Q21DY8
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

203122:SDE RS19030
gene id: 203122:SDE_RS19030
uniprot id: Q21EI1
names: Similarity
messages: Belongs to the YggT family.

203122:SDE RS14175
gene id: 203122:SDE_RS14175
uniprot id: Q21H59
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

203122:SDE RS20330
gene id: 203122:SDE_RS20330
uniprot id: Q21DT6
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the peroxidase family. Peroxidase/catalase subfamily.
messages: Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per dimer.
messages: Formation of the three residue Trp-Tyr-Met cross-link is important for the catalase, but not the peroxidase activity of the enzyme.
messages: Homodimer or homotetramer.

203122:SDE RS18660
gene id: 203122:SDE_RS18660
uniprot id: Q21EQ4
names: Similarity
messages: Belongs to the GSP N family.

203122:SDE RS19180
gene id: 203122:SDE_RS19180
uniprot id: Q21EF3
names: Cofactor
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.
messages: Probably binds two magnesium or manganese ions per subunit.

203122:SDE RS18790
gene id: 203122:SDE_RS18790
uniprot id: Q21EM8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Homodimer. Forms a membrane-associated complex with FtsX.
messages: Part of the ABC transporter FtsEX involved in cellular division. Important for assembly or stability of the septal ring.

203122:SDE RS16630
gene id: 203122:SDE_RS16630
uniprot id: Q21FU6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptC family.
messages: Cell inner membrane
messages: Component of the lipopolysaccharide transport and assembly complex. Interacts with LptA and the LptBFG transporter complex.
messages: Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. Facilitates the transfer of LPS from the inner membrane to the periplasmic protein LptA. Could be a docking site for LptA.

203122:SDE RS16865
gene id: 203122:SDE_RS16865
uniprot id: Q21FP8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell inner membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

203122:SDE RS02010
gene id: 203122:SDE_RS02010
uniprot id: Q21NT4
names: Similarity
messages: Belongs to the stealth family.

203122:SDE RS07260
gene id: 203122:SDE_RS07260
uniprot id: Q21KY1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

203122:SDE RS19080
gene id: 203122:SDE_RS19080
uniprot id: Q21EH1
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.

203122:SDE RS05060
gene id: 203122:SDE_RS05060
uniprot id: Q21M58
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

203122:SDE RS19085
gene id: 203122:SDE_RS19085
uniprot id: Q21EH0
names: Function
names: PTM
names: Similarity
messages: An intermediate of this reaction is the autophosphorylated ppk in which a phosphate is covalently linked to a histidine residue through a N-P bond.
messages: Belongs to the polyphosphate kinase 1 (PPK1) family.
messages: Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP).

203122:SDE RS08435
gene id: 203122:SDE_RS08435
uniprot id: Q21KA8
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

203122:SDE RS05040
gene id: 203122:SDE_RS05040
uniprot id: Q21M62
names: Similarity
messages: Belongs to the UxaA family.

203122:SDE RS20965
gene id: 203122:SDE_RS20965
uniprot id: Q21DG2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

203122:SDE RS02680
gene id: 203122:SDE_RS02680
uniprot id: Q21NH3
names: Similarity
messages: Belongs to the peptidase S41A family.

203122:SDE RS09165
gene id: 203122:SDE_RS09165
uniprot id: Q21JW8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ribosome modulation factor family.
messages: Cytoplasm
messages: During stationary phase, converts 70S ribosomes to an inactive dimeric form (100S ribosomes).

203122:SDE RS05880
gene id: 203122:SDE_RS05880
uniprot id: Q21LP8
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

203122:SDE RS04735
gene id: 203122:SDE_RS04735
uniprot id: Q21MB7
names: Similarity
messages: Belongs to the ArsC family.

203122:SDE RS02095
gene id: 203122:SDE_RS02095
uniprot id: Q21NR7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 1 subfamily.
messages: Cell membrane
messages: Heterotetramer composed of ParC and ParE.
messages: Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.

203122:SDE RS06455
gene id: 203122:SDE_RS06455
uniprot id: Q21LD8
names: Similarity
messages: Belongs to the GbsR family.

203122:SDE RS09175
gene id: 203122:SDE_RS09175
uniprot id: Q21JW6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

203122:SDE RS08350
gene id: 203122:SDE_RS08350
uniprot id: Q21KC4
names: Similarity
messages: Belongs to the glycosyl hydrolase 27 family.

203122:SDE RS05545
gene id: 203122:SDE_RS05545
uniprot id: Q21LW0
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with bS18 to 16S ribosomal RNA.

203122:SDE RS13935
gene id: 203122:SDE_RS13935
uniprot id: Q21HA7
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. HisZ subfamily.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine.
messages: This function is generally fulfilled by the C-terminal part of HisG, which is missing in some bacteria such as this one.

203122:SDE RS10805
gene id: 203122:SDE_RS10805
uniprot id: Q21J11
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
messages: Belongs to the KdsB family.
messages: Cytoplasm

203122:SDE RS16665
gene id: 203122:SDE_RS16665
uniprot id: Q21FT9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

203122:SDE RS00050
gene id: 203122:SDE_RS00050
uniprot id: Q21PU8
names: Subcellular Location Annotation
messages: Membrane

203122:SDE RS13250
gene id: 203122:SDE_RS13250
uniprot id: Q21HN8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ExbD/TolR family.
messages: Cell inner membrane
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

203122:SDE RS08960
gene id: 203122:SDE_RS08960
uniprot id: Q21K06
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PNP synthase family.
messages: Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.
messages: Cytoplasm
messages: Homooctamer; tetramer of dimers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

203122:SDE RS14770
gene id: 203122:SDE_RS14770
uniprot id: Q21GV0
names: Similarity
messages: Belongs to the tRNA methyltransferase O family.

203122:SDE RS19010
gene id: 203122:SDE_RS19010
uniprot id: Q21EI5
names: Similarity
messages: Belongs to the GSP E family.

203122:SDE RS15655
gene id: 203122:SDE_RS15655
uniprot id: Q21GC8
names: Similarity
messages: Belongs to the glycosyl hydrolase 30 family.

203122:SDE RS07630
gene id: 203122:SDE_RS07630
uniprot id: Q21KQ9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseA family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

203122:SDE RS11795
gene id: 203122:SDE_RS11795
uniprot id: Q21IG5
names: Similarity
messages: Belongs to the SdhE FAD assembly factor family.

203122:SDE RS19185
gene id: 203122:SDE_RS19185
uniprot id: Q21EF2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.

203122:SDE RS03365
gene id: 203122:SDE_RS03365
uniprot id: Q21N39
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

203122:SDE RS11065
gene id: 203122:SDE_RS11065
uniprot id: Q21IW0
names: Cofactor
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cell inner membrane
messages: Membrane
messages: Membrane-anchoring subunit of succinate dehydrogenase (SDH).
messages: Part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur protein, plus two membrane-anchoring proteins, SdhC and SdhD.
messages: The heme is bound between the two transmembrane subunits.

203122:SDE RS00650
gene id: 203122:SDE_RS00650
uniprot id: Q21PJ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Membrane

203122:SDE RS12570
gene id: 203122:SDE_RS12570
uniprot id: Q21I18
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfC subfamily.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell inner membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

203122:SDE RS07055
gene id: 203122:SDE_RS07055
uniprot id: Q21L21
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Membrane

203122:SDE RS11605
gene id: 203122:SDE_RS11605
uniprot id: Q21IK2
names: Function
names: Similarity
messages: Belongs to the FlgM family.
messages: Responsible for the coupling of flagellin expression to flagellar assembly by preventing expression of the flagellin genes when a component of the middle class of proteins is defective. It negatively regulates flagellar genes by inhibiting the activity of FliA by directly binding to FliA.

203122:SDE RS18365
gene id: 203122:SDE_RS18365
uniprot id: Q21EW1
names: Similarity
messages: Belongs to the peptidase M24B family.

203122:SDE RS20730
gene id: 203122:SDE_RS20730
uniprot id: Q21DK8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

203122:SDE RS03215
gene id: 203122:SDE_RS03215
uniprot id: Q21N66
names: Subcellular Location Annotation
messages: Membrane

203122:SDE RS11190
gene id: 203122:SDE_RS11190
uniprot id: Q21IT5
names: Similarity
messages: Belongs to the mannose-6-phosphate isomerase type 2 family.

203122:SDE RS19310
gene id: 203122:SDE_RS19310
uniprot id: Q21EC8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

203122:SDE RS09455
gene id: 203122:SDE_RS09455
uniprot id: Q21JR0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

203122:SDE RS10525
gene id: 203122:SDE_RS10525
uniprot id: Q21J66
names: Caution
names: Function
names: Similarity
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.
messages: Catalyzes the 2'-O methylation of guanosine at position 18 in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

203122:SDE RS09760
gene id: 203122:SDE_RS09760
uniprot id: Q21JL0
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. CmoM family.
messages: Catalyzes the methylation of 5-carboxymethoxyuridine (cmo5U) to form 5-methoxycarbonylmethoxyuridine (mcmo5U) at position 34 in tRNAs.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

203122:SDE RS05075
gene id: 203122:SDE_RS05075
uniprot id: Q21M55
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

203122:SDE RS06465
gene id: 203122:SDE_RS06465
uniprot id: Q21LD6
names: Subcellular Location Annotation
messages: Membrane

203122:SDE RS04170
gene id: 203122:SDE_RS04170
uniprot id: Q21MN0
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

203122:SDE RS09750
gene id: 203122:SDE_RS09750
uniprot id: Q21JL2
names: Similarity
messages: Belongs to the peptidase M16 family.

203122:SDE RS05980
gene id: 203122:SDE_RS05980
uniprot id: Q21LM8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Membrane

203122:SDE RS04530
gene id: 203122:SDE_RS04530
uniprot id: Q21MF8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA gyrase inhibitor YacG family.
messages: Binds 1 zinc ion.
messages: Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase.
messages: Interacts with GyrB.

203122:SDE RS05365
gene id: 203122:SDE_RS05365
uniprot id: Q21LZ7
names: Similarity
messages: Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family.

203122:SDE RS10040
gene id: 203122:SDE_RS10040
uniprot id: Q21JF8
names: Similarity
messages: Belongs to the glutamate synthase family.

203122:SDE RS08850
gene id: 203122:SDE_RS08850
uniprot id: Q21K27
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

203122:SDE RS11200
gene id: 203122:SDE_RS11200
uniprot id: Q21IT3
names: Function
names: Similarity
messages: Belongs to the APS kinase family.
messages: Catalyzes the synthesis of activated sulfate.

203122:SDE RS06845
gene id: 203122:SDE_RS06845
uniprot id: Q21L62
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OadG family.
messages: Catalyzes the decarboxylation of oxaloacetate coupled to Na(+) translocation.
messages: Cell membrane
messages: Heterotrimer of an alpha, a beta and a gamma subunit.
messages: Membrane

203122:SDE RS06705
gene id: 203122:SDE_RS06705
uniprot id: Q21L88
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

203122:SDE RS13680
gene id: 203122:SDE_RS13680
uniprot id: Q21HF7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmJ family.
messages: Cytoplasm
messages: Specifically methylates the guanosine in position 1516 of 16S rRNA.

203122:SDE RS20725
gene id: 203122:SDE_RS20725
uniprot id: Q21DK9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

203122:SDE RS13560
gene id: 203122:SDE_RS13560
uniprot id: Q21HI1
names: Similarity
messages: Belongs to the Skp family.

203122:SDE RS05205
gene id: 203122:SDE_RS05205
uniprot id: Q21M28
names: Function
names: Similarity
messages: Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis.
messages: Belongs to the glycogen phosphorylase family.
messages: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.

203122:SDE RS01340
gene id: 203122:SDE_RS01340
uniprot id: Q21P62
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

203122:SDE RS06860
gene id: 203122:SDE_RS06860
uniprot id: Q21L59
names: Similarity
messages: Belongs to the pyruvate kinase family.

203122:SDE RS15830
gene id: 203122:SDE_RS15830
uniprot id: Q21GA0
names: Similarity
messages: Belongs to the glycosyl hydrolase 26 family.

203122:SDE RS12780
gene id: 203122:SDE_RS12780
uniprot id: Q21HX7
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

203122:SDE RS13545
gene id: 203122:SDE_RS13545
uniprot id: Q21HI4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxA subfamily.
messages: Cytoplasm
messages: Homotrimer.
messages: Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

203122:SDE RS01750
gene id: 203122:SDE_RS01750
uniprot id: Q21NY3
names: Similarity
messages: Belongs to the prokaryotic/mitochondrial release factor family.

203122:SDE RS07225
gene id: 203122:SDE_RS07225
uniprot id: Q21KY8
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

203122:SDE RS00135
gene id: 203122:SDE_RS00135
uniprot id: Q21PU0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the aerobic coproporphyrinogen-III oxidase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX.

203122:SDE RS14115
gene id: 203122:SDE_RS14115
uniprot id: Q21H71
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
messages: Belongs to the ClpX chaperone family. HslU subfamily.
messages: Cytoplasm

203122:SDE RS01850
gene id: 203122:SDE_RS01850
uniprot id: Q21NW6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell inner membrane

203122:SDE RS06445
gene id: 203122:SDE_RS06445
uniprot id: Q21LE0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

203122:SDE RS11555
gene id: 203122:SDE_RS11555
uniprot id: Q21IL2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
messages: Bacterial flagellum basal body
messages: Belongs to the FlgH family.
messages: Cell outer membrane
messages: Membrane
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod.

203122:SDE RS05595
gene id: 203122:SDE_RS05595
uniprot id: Q21LV0
names: Function
names: PTM
names: Similarity
messages: Acetylated. Deacetylation by the SIR2-homolog deacetylase activates the enzyme.
messages: Belongs to the ATP-dependent AMP-binding enzyme family.
messages: Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.

203122:SDE RS04540
gene id: 203122:SDE_RS04540
uniprot id: Q21MF6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A24 family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Plays an essential role in type IV pili and type II pseudopili formation by proteolytically removing the leader sequence from substrate proteins and subsequently monomethylating the alpha-amino group of the newly exposed N-terminal phenylalanine.

203122:SDE RS03155
gene id: 203122:SDE_RS03155
uniprot id: Q21N78
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

203122:SDE RS04035
gene id: 203122:SDE_RS04035
uniprot id: Q21MQ7
names: Similarity
messages: Belongs to the peptidase M1 family.

203122:SDE RS04455
gene id: 203122:SDE_RS04455
uniprot id: Q21MH3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

203122:SDE RS03820
gene id: 203122:SDE_RS03820
uniprot id: Q21MV0
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

203122:SDE RS14275
gene id: 203122:SDE_RS14275
uniprot id: Q21H41
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

203122:SDE RS06460
gene id: 203122:SDE_RS06460
uniprot id: Q21LD7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Monomer.

203122:SDE RS04550
gene id: 203122:SDE_RS04550
uniprot id: Q21MF4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP E family.
messages: Cytoplasm

203122:SDE RS04300
gene id: 203122:SDE_RS04300
uniprot id: Q21MK4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

203122:SDE RS12985
gene id: 203122:SDE_RS12985
uniprot id: Q21HT6
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Monomer.

203122:SDE RS17635
gene id: 203122:SDE_RS17635
uniprot id: Q21FA2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DksA family.
messages: Cytoplasm
messages: Interacts directly with the RNA polymerase.
messages: Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters. Also required for regulation of fis expression.

203122:SDE RS03830
gene id: 203122:SDE_RS03830
uniprot id: Q21MU8
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

203122:SDE RS13155
gene id: 203122:SDE_RS13155
uniprot id: Q21HQ5
names: Function
names: Similarity
messages: Belongs to the SELO family.
messages: Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr or Tyr residues of target proteins (AMPylation).

203122:SDE RS05200
gene id: 203122:SDE_RS05200
uniprot id: Q21M29
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

203122:SDE RS19610
gene id: 203122:SDE_RS19610
uniprot id: Q21E70
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

203122:SDE RS09805
gene id: 203122:SDE_RS09805
uniprot id: Q21JK1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmC/CycZ/HelC family.
messages: Cell inner membrane
messages: Membrane
messages: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.

203122:SDE RS05195
gene id: 203122:SDE_RS05195
uniprot id: Q21M30
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
messages: Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.
messages: Monomer.

203122:SDE RS12645
gene id: 203122:SDE_RS12645
uniprot id: Q21I03
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

203122:SDE RS05150
gene id: 203122:SDE_RS05150
uniprot id: Q21M41
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

203122:SDE RS16540
gene id: 203122:SDE_RS16540
uniprot id: Q21FW4
names: Subcellular Location Annotation
messages: Membrane

203122:SDE RS17475
gene id: 203122:SDE_RS17475
uniprot id: Q21FD4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEDS family. MrdB/RodA subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Peptidoglycan polymerase that is essential for cell wall elongation.

203122:SDE RS05710
gene id: 203122:SDE_RS05710
uniprot id: Q21LS7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

203122:SDE RS08775
gene id: 203122:SDE_RS08775
uniprot id: Q21K42
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm

203122:SDE RS20720
gene id: 203122:SDE_RS20720
uniprot id: Q21DL0
names: Subcellular Location Annotation
messages: Membrane

203122:SDE RS03935
gene id: 203122:SDE_RS03935
uniprot id: Q21MS7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptD family.
messages: Cell outer membrane
messages: Component of the lipopolysaccharide transport and assembly complex. Interacts with LptE and LptA.
messages: Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane.

203122:SDE RS13265
gene id: 203122:SDE_RS13265
uniprot id: Q21HN5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvA family.
messages: Cytoplasm
messages: Has three domains with a flexible linker between the domains II and III and assumes an 'L' shape. Domain III is highly mobile and contacts RuvB.
messages: Homotetramer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

203122:SDE RS04555
gene id: 203122:SDE_RS04555
uniprot id: Q21MF3
names: Similarity
messages: Belongs to the N-Me-Phe pilin family.

203122:SDE RS12550
gene id: 203122:SDE_RS12550
uniprot id: Q21I22
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.

203122:SDE RS07365
gene id: 203122:SDE_RS07365
uniprot id: Q21KW1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.

203122:SDE RS13860
gene id: 203122:SDE_RS13860
uniprot id: Q21HC2
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

203122:SDE RS06755
gene id: 203122:SDE_RS06755
uniprot id: Q21L78
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecX family.
messages: Cytoplasm
messages: Modulates RecA activity.

203122:SDE RS17380
gene id: 203122:SDE_RS17380
uniprot id: Q21FF3
names: Similarity
messages: Belongs to the YciI family.

203122:SDE RS08875
gene id: 203122:SDE_RS08875
uniprot id: Q21K22
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.

203122:SDE RS16620
gene id: 203122:SDE_RS16620
uniprot id: Q21FU8
names: Similarity
messages: Belongs to the SIS family. GutQ/KpsF subfamily.

203122:SDE RS13780
gene id: 203122:SDE_RS13780
uniprot id: Q21HD7
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

203122:SDE RS17595
gene id: 203122:SDE_RS17595
uniprot id: Q21FB0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PPase family.
messages: Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
messages: Cytoplasm
messages: Homohexamer.

203122:SDE RS11055
gene id: 203122:SDE_RS11055
uniprot id: Q21IW2
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.

203122:SDE RS03695
gene id: 203122:SDE_RS03695
uniprot id: Q21MX3
names: Similarity
messages: Belongs to the YciI family.

203122:SDE RS04850
gene id: 203122:SDE_RS04850
uniprot id: Q21M99
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

203122:SDE RS04080
gene id: 203122:SDE_RS04080
uniprot id: Q21MP8
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

203122:SDE RS07010
gene id: 203122:SDE_RS07010
uniprot id: Q21L30
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

203122:SDE RS10415
gene id: 203122:SDE_RS10415
uniprot id: Q21J87
names: Subcellular Location Annotation
messages: Membrane

203122:SDE RS10910
gene id: 203122:SDE_RS10910
uniprot id: Q21IZ1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

203122:SDE RS16855
gene id: 203122:SDE_RS16855
uniprot id: Q21FQ0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PRA-CH family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.
messages: Cytoplasm
messages: Homodimer.

203122:SDE RS00705
gene id: 203122:SDE_RS00705
uniprot id: Q21PH9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

203122:SDE RS16595
gene id: 203122:SDE_RS16595
uniprot id: Q21FV3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Lacks the C-terminal regulatory region which is replaced by HisZ.

203122:SDE RS15815
gene id: 203122:SDE_RS15815
uniprot id: Q21GA2
names: Subcellular Location Annotation
messages: Secreted

203122:SDE RS05120
gene id: 203122:SDE_RS05120
uniprot id: Q21M47
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

203122:SDE RS05090
gene id: 203122:SDE_RS05090
uniprot id: Q21M52
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity).

203122:SDE RS08965
gene id: 203122:SDE_RS08965
uniprot id: Q21K05
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

203122:SDE RS16770
gene id: 203122:SDE_RS16770
uniprot id: Q21FR8
names: Function
names: Similarity
messages: Belongs to the CobU/CobP family.
messages: Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate.

203122:SDE RS09995
gene id: 203122:SDE_RS09995
uniprot id: Q21JG6
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

203122:SDE RS18665
gene id: 203122:SDE_RS18665
uniprot id: Q21EQ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP M family.
messages: Cell inner membrane
messages: Inner membrane component of the type II secretion system required for the energy-dependent secretion of extracellular factors such as proteases and toxins from the periplasm.
messages: Membrane

203122:SDE RS11545
gene id: 203122:SDE_RS11545
uniprot id: Q21IL4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Flagellum-specific muramidase which hydrolyzes the peptidoglycan layer to assemble the rod structure in the periplasmic space.
messages: In the C-terminal section; belongs to the glycosyl hydrolase 73 family.
messages: In the N-terminal section; belongs to the FlgJ family.
messages: Periplasm

203122:SDE RS06690
gene id: 203122:SDE_RS06690
uniprot id: Q21L91
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PNT beta subunit family.
messages: Cell inner membrane
messages: Heterodimer of an alpha and a beta chain.
messages: Membrane
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

203122:SDE RS11940
gene id: 203122:SDE_RS11940
uniprot id: Q21ID6
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

203122:SDE RS10085
gene id: 203122:SDE_RS10085
uniprot id: Q21JE9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

203122:SDE RS06415
gene id: 203122:SDE_RS06415
uniprot id: Q21LE6
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic AdoMetDC family. Type 1 subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine.
messages: Heterotetramer of two alpha and two beta chains arranged as a dimer of alpha/beta heterodimers.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl group blocking the N-terminus of the alpha chain.

203122:SDE RS19515
gene id: 203122:SDE_RS19515
uniprot id: Q21E89
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

203122:SDE RS03380
gene id: 203122:SDE_RS03380
uniprot id: Q21N36
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobS family.
messages: Cell inner membrane
messages: Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.
messages: Membrane

203122:SDE RS16725
gene id: 203122:SDE_RS16725
uniprot id: Q21FS7
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

203122:SDE RS13645
gene id: 203122:SDE_RS13645
uniprot id: Q21HG4
names: Similarity
messages: Belongs to the ArsC family.

203122:SDE RS09905
gene id: 203122:SDE_RS09905
uniprot id: Q21JI4
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

203122:SDE RS06530
gene id: 203122:SDE_RS06530
uniprot id: Q21LC3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KdsA family.
messages: Cytoplasm

203122:SDE RS09395
gene id: 203122:SDE_RS09395
uniprot id: Q21JS2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NqrA family.
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

203122:SDE RS14325
gene id: 203122:SDE_RS14325
uniprot id: Q21H32
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamE family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

203122:SDE RS08740
gene id: 203122:SDE_RS08740
uniprot id: Q21K49
names: Cofactor
messages: Binds 1 Mg(2+) ion per subunit.

203122:SDE RS12775
gene id: 203122:SDE_RS12775
uniprot id: Q21HX8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm

203122:SDE RS08515
gene id: 203122:SDE_RS08515
uniprot id: Q21K93
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YceF subfamily.
messages: Cytoplasm
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes 7-methyl-GTP (m(7)GTP). May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

203122:SDE RS17805
gene id: 203122:SDE_RS17805
uniprot id: Q21F69
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

203122:SDE RS11235
gene id: 203122:SDE_RS11235
uniprot id: Q21IS6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.
messages: Heterodimer composed of CysD, the smaller subunit, and CysN.
messages: With CysD forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway. APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD.

203122:SDE RS14420
gene id: 203122:SDE_RS14420
uniprot id: Q21H13
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

203122:SDE RS09825
gene id: 203122:SDE_RS09825
uniprot id: Q21JJ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbE subfamily.
messages: Cell inner membrane

203122:SDE RS09460
gene id: 203122:SDE_RS09460
uniprot id: Q21JQ9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. Lipoprotein translocase (TC 3.A.1.125) family.
messages: Cell inner membrane
messages: Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner.
messages: The complex is composed of two ATP-binding proteins (LolD) and two transmembrane proteins (LolC and LolE).

203122:SDE RS05565
gene id: 203122:SDE_RS05565
uniprot id: Q21LV6
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

203122:SDE RS04105
gene id: 203122:SDE_RS04105
uniprot id: Q21MP3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the arabinose isomerase family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the conversion of L-arabinose to L-ribulose.

203122:SDE RS03505
gene id: 203122:SDE_RS03505
uniprot id: Q21N11
names: Similarity
messages: Belongs to the glycosyl hydrolase 5 (cellulase A) family.

203122:SDE RS06980
gene id: 203122:SDE_RS06980
uniprot id: Q21L36
names: Similarity
messages: Belongs to the thioredoxin family.

203122:SDE RS09685
gene id: 203122:SDE_RS09685
uniprot id: Q21JM5
names: Similarity
messages: Belongs to the YoeB family.

203122:SDE RS01795
gene id: 203122:SDE_RS01795
uniprot id: Q21NX7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvT family.
messages: The glycine cleavage system catalyzes the degradation of glycine.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

203122:SDE RS14040
gene id: 203122:SDE_RS14040
uniprot id: Q21H86
names: Similarity
messages: Belongs to the glutamate synthase family.

203122:SDE RS09025
gene id: 203122:SDE_RS09025
uniprot id: Q21JZ4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial diacylglycerol kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of sn-l,2-diacylglycerol (DAG) to phosphatidic acid. Involved in the recycling of diacylglycerol produced as a by-product during membrane-derived oligosaccharide (MDO) biosynthesis.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Mn(2+), Zn(2+), Cd(2+) and Co(2+) support activity to lesser extents.

203122:SDE RS04485
gene id: 203122:SDE_RS04485
uniprot id: Q21MG7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

203122:SDE RS00090
gene id: 203122:SDE_RS00090
uniprot id: Q21PW0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0114 family.
messages: Cell membrane
messages: Membrane

203122:SDE RS07420
gene id: 203122:SDE_RS07420
uniprot id: Q21KV1
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

203122:SDE RS00165
gene id: 203122:SDE_RS00165
uniprot id: Q21PT4
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

203122:SDE RS11245
gene id: 203122:SDE_RS11245
uniprot id: Q21IS4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PAPS reductase family. CysD subfamily.
messages: Heterodimer composed of CysD, the smaller subunit, and CysN.
messages: With CysN forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway. APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD.

203122:SDE RS11385
gene id: 203122:SDE_RS11385
uniprot id: Q21IP7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliP/MopC/SpaP family.
messages: Cell membrane
messages: Membrane
messages: Plays a role in the flagellum-specific transport system.

203122:SDE RS01800
gene id: 203122:SDE_RS01800
uniprot id: Q21NX6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

203122:SDE RS01885
gene id: 203122:SDE_RS01885
uniprot id: Q21NV9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

203122:SDE RS18960
gene id: 203122:SDE_RS18960
uniprot id: Q21EJ5
names: Function
messages: Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors. CheA is autophosphorylated; it can transfer its phosphate group to either CheB or CheY.

203122:SDE RS11355
gene id: 203122:SDE_RS11355
uniprot id: Q21IQ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTP-binding SRP family.
messages: Cell membrane
messages: Membrane
messages: Necessary for flagellar biosynthesis. May be involved in translocation of the flagellum.

203122:SDE RS19220
gene id: 203122:SDE_RS19220
uniprot id: Q21EE5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

203122:SDE RS16660
gene id: 203122:SDE_RS16660
uniprot id: Q21FU0
names: Subcellular Location Annotation
messages: Cytoplasm

203122:SDE RS05815
gene id: 203122:SDE_RS05815
uniprot id: Q21LR1
names: Subcellular Location Annotation
messages: Cytoplasm

203122:SDE RS11400
gene id: 203122:SDE_RS11400
uniprot id: Q21IP4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliM family.
messages: Cell inner membrane
messages: FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
messages: Membrane

203122:SDE RS07025
gene id: 203122:SDE_RS07025
uniprot id: Q21L27
names: Similarity
messages: Belongs to the UPF0260 family.

203122:SDE RS04800
gene id: 203122:SDE_RS04800
uniprot id: Q21MA4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homodimer.

203122:SDE RS04145
gene id: 203122:SDE_RS04145
uniprot id: Q21MN5
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

203122:SDE RS05155
gene id: 203122:SDE_RS05155
uniprot id: Q21M39
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

203122:SDE RS04870
gene id: 203122:SDE_RS04870
uniprot id: Q21M95
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

203122:SDE RS07395
gene id: 203122:SDE_RS07395
uniprot id: Q21KV6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.
messages: Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA.
messages: Cytoplasm
messages: Homodimer.

203122:SDE RS00190
gene id: 203122:SDE_RS00190
uniprot id: Q21PS9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 2 family.
messages: Binds a copper A center.
messages: Cell membrane
messages: Membrane
messages: Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B).

203122:SDE RS04000
gene id: 203122:SDE_RS04000
uniprot id: Q21MR4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.

203122:SDE RS04360
gene id: 203122:SDE_RS04360
uniprot id: Q21MJ2
names: Function
names: Similarity
messages: Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits).
messages: In the C-terminal section; belongs to the transpeptidase family.
messages: In the N-terminal section; belongs to the glycosyltransferase 51 family.

203122:SDE RS15285
gene id: 203122:SDE_RS15285
uniprot id: Q21GJ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell inner membrane
messages: Membrane

203122:SDE RS18655
gene id: 203122:SDE_RS18655
uniprot id: Q21EQ5
names: Cofactor
names: Similarity
messages: Belongs to the ApbE family.
messages: Magnesium. Can also use manganese.

203122:SDE RS11780
gene id: 203122:SDE_RS11780
uniprot id: Q21IG8
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

203122:SDE RS04890
gene id: 203122:SDE_RS04890
uniprot id: Q21M91
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

203122:SDE RS19075
gene id: 203122:SDE_RS19075
uniprot id: Q21EH2
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

203122:SDE RS21600
gene id: 203122:SDE_RS21600
uniprot id: Q21EU6
names: Similarity
messages: Belongs to the GST superfamily.

203122:SDE RS14315
gene id: 203122:SDE_RS14315
uniprot id: Q21H34
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

203122:SDE RS21390
gene id: 203122:SDE_RS21390
uniprot id: Q21HD3
names: Similarity
messages: Belongs to the glycosyl hydrolase 5 (cellulase A) family.

203122:SDE RS20760
gene id: 203122:SDE_RS20760
uniprot id: Q21DK2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase A chain family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.

203122:SDE RS17025
gene id: 203122:SDE_RS17025
uniprot id: Q21FM0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LolB family.
messages: Cell outer membrane
messages: Membrane
messages: Monomer.
messages: Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein.

203122:SDE RS12540
gene id: 203122:SDE_RS12540
uniprot id: Q21I24
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.

203122:SDE RS09880
gene id: 203122:SDE_RS09880
uniprot id: Q21JI8
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.

203122:SDE RS14680
gene id: 203122:SDE_RS14680
uniprot id: Q21GW8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

203122:SDE RS08610
gene id: 203122:SDE_RS08610
uniprot id: Q21K75
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

203122:SDE RS12505
gene id: 203122:SDE_RS12505
uniprot id: Q21I31
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

203122:SDE RS11715
gene id: 203122:SDE_RS11715
uniprot id: Q21II1
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

203122:SDE RS08565
gene id: 203122:SDE_RS08565
uniprot id: Q21K83
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

203122:SDE RS09420
gene id: 203122:SDE_RS09420
uniprot id: Q21JR7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrF family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Cell inner membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway.

203122:SDE RS14735
gene id: 203122:SDE_RS14735
uniprot id: Q21GV7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

203122:SDE RS13950
gene id: 203122:SDE_RS13950
uniprot id: Q21HA4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the band 7/mec-2 family. HflK subfamily.
messages: HflC and HflK could encode or regulate a protease.
messages: HflC and HflK may interact to form a multimeric complex.
messages: Membrane

203122:SDE RS16720
gene id: 203122:SDE_RS16720
uniprot id: Q21FS8
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

203122:SDE RS06750
gene id: 203122:SDE_RS06750
uniprot id: Q21L79
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

203122:SDE RS14675
gene id: 203122:SDE_RS14675
uniprot id: Q21GW9
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

203122:SDE RS09785
gene id: 203122:SDE_RS09785
uniprot id: Q21JK5
names: Similarity
messages: Belongs to the type III secretion exporter family.

203122:SDE RS15985
gene id: 203122:SDE_RS15985
uniprot id: Q21G70
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

203122:SDE RS06110
gene id: 203122:SDE_RS06110
uniprot id: Q21LK2
names: Cofactor
names: Similarity
messages: Belongs to the MsrB Met sulfoxide reductase family.
messages: Binds 1 zinc ion per subunit. The zinc ion is important for the structural integrity of the protein.

203122:SDE RS02745
gene id: 203122:SDE_RS02745
uniprot id: Q21NG0
names: Similarity
messages: Belongs to the N-acylglucosamine 2-epimerase family.

203122:SDE RS03145
gene id: 203122:SDE_RS03145
uniprot id: Q21N80
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Cell inner membrane
messages: Homoheptamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mechanosensitive channel that participates in the regulation of osmotic pressure changes within the cell, opening in response to stretch forces in the membrane lipid bilayer, without the need for other proteins. Contributes to normal resistance to hypoosmotic shock. Forms an ion channel of 1.0 nanosiemens conductance with a slight preference for anions.
messages: Membrane

203122:SDE RS00270
gene id: 203122:SDE_RS00270
uniprot id: Q21PR3
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.

203122:SDE RS14150
gene id: 203122:SDE_RS14150
uniprot id: Q21H64
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

203122:SDE RS15105
gene id: 203122:SDE_RS15105
uniprot id: Q21GN3
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

203122:SDE RS13745
gene id: 203122:SDE_RS13745
uniprot id: Q21HE4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TER reductase family.
messages: Involved in the final reduction of the elongation cycle of fatty acid synthesis (FAS II). Catalyzes the reduction of a carbon-carbon double bond in an enoyl moiety that is covalently linked to an acyl carrier protein (ACP).
messages: Monomer.

203122:SDE RS00430
gene id: 203122:SDE_RS00430
uniprot id: Q21PN1
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. NasA/NapA/NarB subfamily.
messages: Binds 1 [4Fe-4S] cluster.
messages: Binds 1 molybdenum-bis(molybdopterin guanine dinucleotide) (Mo-bis-MGD) cofactor per subunit.
messages: Catalytic subunit of the periplasmic nitrate reductase complex NapAB. Receives electrons from NapB and catalyzes the reduction of nitrate to nitrite.
messages: Component of the periplasmic nitrate reductase NapAB complex composed of NapA and NapB.
messages: Periplasm
messages: Predicted to be exported by the Tat system. The position of the signal peptide cleavage has not been experimentally proven.

203122:SDE RS15885
gene id: 203122:SDE_RS15885
uniprot id: Q21G89
names: Similarity
messages: Belongs to the UPF0178 family.

203122:SDE RS18620
gene id: 203122:SDE_RS18620
uniprot id: Q21ER2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

203122:SDE RS04175
gene id: 203122:SDE_RS04175
uniprot id: Q21MM9
names: Similarity
messages: Belongs to the aldose epimerase family.

203122:SDE RS04815
gene id: 203122:SDE_RS04815
uniprot id: Q21MA1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

203122:SDE RS05310
gene id: 203122:SDE_RS05310
uniprot id: Q21M08
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

203122:SDE RS11040
gene id: 203122:SDE_RS11040
uniprot id: Q21IW5
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

203122:SDE RS18940
gene id: 203122:SDE_RS18940
uniprot id: Q21EJ9
names: Similarity
messages: Belongs to the HSP15 family.

203122:SDE RS20970
gene id: 203122:SDE_RS20970
uniprot id: Q21DG1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
messages: Binds 1 potassium ion per subunit.
messages: Cytoplasm
messages: Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.

203122:SDE RS00185
gene id: 203122:SDE_RS00185
uniprot id: Q21PT0
names: Subcellular Location Annotation
messages: Membrane

203122:SDE RS18735
gene id: 203122:SDE_RS18735
uniprot id: Q21EN9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DsbB family.
messages: Cell inner membrane
messages: Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein.

203122:SDE RS13580
gene id: 203122:SDE_RS13580
uniprot id: Q21HH7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

203122:SDE RS04295
gene id: 203122:SDE_RS04295
uniprot id: Q21MK5
names: Function
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

203122:SDE RS03500
gene id: 203122:SDE_RS03500
uniprot id: Q21N12
names: Cofactor
names: Similarity
messages: Belongs to the alkaline phosphatase family.
messages: Binds 1 Mg(2+) ion.
messages: Binds 2 Zn(2+) ions.

203122:SDE RS13555
gene id: 203122:SDE_RS13555
uniprot id: Q21HI2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
messages: Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
messages: Homotrimer.

203122:SDE RS14330
gene id: 203122:SDE_RS14330
uniprot id: Q21H31
names: Similarity
messages: Belongs to the UPF0125 (RnfH) family.

203122:SDE RS02730
gene id: 203122:SDE_RS02730
uniprot id: Q21NG3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glutamine synthetase family.
messages: Cytoplasm
messages: Oligomer of 12 subunits arranged in the form of two hexagons.

203122:SDE RS05190
gene id: 203122:SDE_RS05190
uniprot id: Q21M31
names: Similarity
messages: Belongs to the disproportionating enzyme family.

203122:SDE RS05670
gene id: 203122:SDE_RS05670
uniprot id: Q21LT5
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Alleviates ribosome stalling that occurs when 3 or more consecutive Pro residues or the sequence PPG is present in a protein, possibly by augmenting the peptidyl transferase activity of the ribosome. Modification of Lys-34 is required for alleviation.
messages: May be beta-lysylated on the epsilon-amino group of Lys-34 by the combined action of EpmA and EpmB, and then hydroxylated on the C5 position of the same residue by EpmC (if this protein is present). Lysylation is critical for the stimulatory effect of EF-P on peptide-bond formation. The lysylation moiety may extend toward the peptidyltransferase center and stabilize the terminal 3-CCA end of the tRNA. Hydroxylation of the C5 position on Lys-34 may allow additional potential stabilizing hydrogen-bond interactions with the P-tRNA.

203122:SDE RS09730
gene id: 203122:SDE_RS09730
uniprot id: Q21JL6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. Cx-SAM synthase family.
messages: Catalyzes the conversion of S-adenosyl-L-methionine (SAM) to carboxy-S-adenosyl-L-methionine (Cx-SAM).
messages: Homodimer.

203122:SDE RS15895
gene id: 203122:SDE_RS15895
uniprot id: Q21G87
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

203122:SDE RS20745
gene id: 203122:SDE_RS20745
uniprot id: Q21DK5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase delta chain family.
messages: Cell inner membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

203122:SDE RS18785
gene id: 203122:SDE_RS18785
uniprot id: Q21EM9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
messages: Cell inner membrane
messages: Forms a membrane-associated complex with FtsE.
messages: Membrane
messages: Part of the ABC transporter FtsEX involved in cellular division.

203122:SDE RS08810
gene id: 203122:SDE_RS08810
uniprot id: Q21K35
names: Cofactor
names: Similarity
messages: Belongs to the monomeric-type IDH family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

203122:SDE RS19315
gene id: 203122:SDE_RS19315
uniprot id: Q21EC7
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

203122:SDE RS00205
gene id: 203122:SDE_RS00205
uniprot id: Q21PS6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Membrane

203122:SDE RS06340
gene id: 203122:SDE_RS06340
uniprot id: Q21LG1
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

203122:SDE RS08140
gene id: 203122:SDE_RS08140
uniprot id: Q21KG3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily.
messages: Cytoplasm
messages: Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity.

203122:SDE RS21565
gene id: 203122:SDE_RS21565
uniprot id: Q21FE9
names: Similarity
messages: Belongs to the peptidase S8 family.

203122:SDE RS06985
gene id: 203122:SDE_RS06985
uniprot id: Q21L35
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.

203122:SDE RS10295
gene id: 203122:SDE_RS10295
uniprot id: Q21JB1
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

203122:SDE RS12925
gene id: 203122:SDE_RS12925
uniprot id: Q21HU8
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

203122:SDE RS19240
gene id: 203122:SDE_RS19240
uniprot id: Q21EE1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase PH family.
messages: Homohexameric ring arranged as a trimer of dimers.
messages: Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.

203122:SDE RS19245
gene id: 203122:SDE_RS19245
uniprot id: Q21EE0
names: Similarity
messages: Belongs to the YicC/YloC family.

203122:SDE RS19605
gene id: 203122:SDE_RS19605
uniprot id: Q21E71
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Membrane

203122:SDE RS18600
gene id: 203122:SDE_RS18600
uniprot id: Q21ER6
names: Subcellular Location Annotation
messages: Cytoplasm

203122:SDE RS14300
gene id: 203122:SDE_RS14300
uniprot id: Q21H37
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

203122:SDE RS17275
gene id: 203122:SDE_RS17275
uniprot id: Q21FH4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methylthiotransferase family. MiaB subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
messages: Cytoplasm
messages: Monomer.

203122:SDE RS09170
gene id: 203122:SDE_RS09170
uniprot id: Q21JW7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RlmKL family.
messages: Cytoplasm
messages: Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA.

203122:SDE RS01260
gene id: 203122:SDE_RS01260
uniprot id: Q21P78
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.

203122:SDE RS08720
gene id: 203122:SDE_RS08720
uniprot id: Q21K53
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

203122:SDE RS05225
gene id: 203122:SDE_RS05225
uniprot id: Q21M24
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

203122:SDE RS02665
gene id: 203122:SDE_RS02665
uniprot id: Q21NH5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

203122:SDE RS07710
gene id: 203122:SDE_RS07710
uniprot id: Q21KP5
names: Function
names: Similarity
messages: Belongs to the flavodoxin family.
messages: Low-potential electron donor to a number of redox enzymes.

203122:SDE RS18390
gene id: 203122:SDE_RS18390
uniprot id: Q21EV7
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

203122:SDE RS00300
gene id: 203122:SDE_RS00300
uniprot id: Q21PQ7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. Zinc importer (TC 3.A.1.15.5) family.
messages: Cell inner membrane
messages: Part of the ABC transporter complex ZnuABC involved in zinc import. Responsible for energy coupling to the transport system.
messages: The complex is composed of two ATP-binding proteins (ZnuC), two transmembrane proteins (ZnuB) and a solute-binding protein (ZnuA).

203122:SDE RS04120
gene id: 203122:SDE_RS04120
uniprot id: Q21MP0
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

203122:SDE RS14710
gene id: 203122:SDE_RS14710
uniprot id: Q21GW2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

203122:SDE RS03635
gene id: 203122:SDE_RS03635
uniprot id: Q21MY5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

203122:SDE RS00470
gene id: 203122:SDE_RS00470
uniprot id: Q21PM3
names: Similarity
messages: Belongs to the HipA Ser/Thr kinase family.

203122:SDE RS10985
gene id: 203122:SDE_RS10985
uniprot id: Q21IX6
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family.
messages: Homopolymer.

203122:SDE RS14745
gene id: 203122:SDE_RS14745
uniprot id: Q21GV5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

203122:SDE RS13380
gene id: 203122:SDE_RS13380
uniprot id: Q21HL7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamD family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

203122:SDE RS02020
gene id: 203122:SDE_RS02020
uniprot id: Q21NT2
names: Similarity
messages: Belongs to the Gfa family.

203122:SDE RS06555
gene id: 203122:SDE_RS06555
uniprot id: Q21LB8
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruD family.
messages: Responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs.

203122:SDE RS13730
gene id: 203122:SDE_RS13730
uniprot id: Q21HE7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

203122:SDE RS08915
gene id: 203122:SDE_RS08915
uniprot id: Q7PC52
names: Similarity
messages: Belongs to the glycosyl hydrolase 18 family.

203122:SDE RS05050
gene id: 203122:SDE_RS05050
uniprot id: Q21M60
names: Function
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

203122:SDE RS04975
gene id: 203122:SDE_RS04975
uniprot id: Q21M75
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polysaccharide lyase 1 family.
messages: Secreted

203122:SDE RS04865
gene id: 203122:SDE_RS04865
uniprot id: Q21M96
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

203122:SDE RS06805
gene id: 203122:SDE_RS06805
uniprot id: Q21L68
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

203122:SDE RS16370
gene id: 203122:SDE_RS16370
uniprot id: Q21FZ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endonuclease V family.
messages: Cytoplasm
messages: DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA.

203122:SDE RS05275
gene id: 203122:SDE_RS05275
uniprot id: Q21M15
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DoxX family.
messages: Membrane

203122:SDE RS08735
gene id: 203122:SDE_RS08735
uniprot id: Q21K50
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAPS reductase family. CysH subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of sulfite from adenosine 5'-phosphosulfate (APS) using thioredoxin as an electron donor.
messages: Cytoplasm

203122:SDE RS05315
gene id: 203122:SDE_RS05315
uniprot id: Q21M07
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

203122:SDE RS18275
gene id: 203122:SDE_RS18275
uniprot id: Q21EX9
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

203122:SDE RS01180
gene id: 203122:SDE_RS01180
uniprot id: Q21P94
names: Cofactor
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family.
messages: Binds 2 nickel ions per subunit.
messages: Carboxylation allows a single lysine to coordinate two nickel ions.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

203122:SDE RS11035
gene id: 203122:SDE_RS11035
uniprot id: Q21IW6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

203122:SDE RS02850
gene id: 203122:SDE_RS02850
uniprot id: Q21ND9
names: Subcellular Location Annotation
messages: Membrane

203122:SDE RS09245
gene id: 203122:SDE_RS09245
uniprot id: Q21JV2
names: Similarity
messages: Belongs to the glycosyl hydrolase 51 family.

203122:SDE RS11965
gene id: 203122:SDE_RS11965
uniprot id: Q21ID1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

203122:SDE RS07685
gene id: 203122:SDE_RS07685
uniprot id: Q21KQ0
names: Subcellular Location Annotation
messages: Membrane

203122:SDE RS01610
gene id: 203122:SDE_RS01610
uniprot id: Q21P11
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. METTL16/RlmF family.
messages: Cytoplasm
messages: Specifically methylates the adenine in position 1618 of 23S rRNA.

203122:SDE RS17320
gene id: 203122:SDE_RS17320
uniprot id: Q21FG5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptE lipoprotein family.
messages: Cell outer membrane
messages: Component of the lipopolysaccharide transport and assembly complex. Interacts with LptD.
messages: Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane.

203122:SDE RS07760
gene id: 203122:SDE_RS07760
uniprot id: Q21KN5
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.

203122:SDE RS04465
gene id: 203122:SDE_RS04465
uniprot id: Q21MH1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

203122:SDE RS14510
gene id: 203122:SDE_RS14510
uniprot id: Q21GZ5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

203122:SDE RS08820
gene id: 203122:SDE_RS08820
uniprot id: Q21K33
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ClpS family.
messages: Binds to the N-terminal domain of the chaperone ClpA.
messages: Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation.

203122:SDE RS08560
gene id: 203122:SDE_RS08560
uniprot id: Q21K84
names: Function
names: Similarity
messages: Belongs to the transglycosylase MltG family.
messages: Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.

203122:SDE RS08970
gene id: 203122:SDE_RS08970
uniprot id: Q21K04
names: Subcellular Location Annotation
messages: Membrane

203122:SDE RS13670
gene id: 203122:SDE_RS13670
uniprot id: Q21HF9
names: Similarity
names: Subunit
messages: Belongs to the MoaE family.
messages: Heterotetramer of 2 MoaD subunits and 2 MoaE subunits. Also stable as homodimer. The enzyme changes between these two forms during catalysis.

203122:SDE RS11850
gene id: 203122:SDE_RS11850
uniprot id: Q21IF4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

203122:SDE RS05320
gene id: 203122:SDE_RS05320
uniprot id: Q21M06
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm

203122:SDE RS07515
gene id: 203122:SDE_RS07515
uniprot id: Q21KT2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

203122:SDE RS01235
gene id: 203122:SDE_RS01235
uniprot id: Q21P83
names: Similarity
messages: Belongs to the P(II) protein family.

203122:SDE RS01170
gene id: 203122:SDE_RS01170
uniprot id: Q21P96
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the urease gamma subunit family.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

203122:SDE RS04660
gene id: 203122:SDE_RS04660
uniprot id: Q21MD2
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

203122:SDE RS14780
gene id: 203122:SDE_RS14780
uniprot id: Q21GU8
names: Function
names: Similarity
messages: Belongs to the cyanase family.
messages: Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide.

203122:SDE RS03840
gene id: 203122:SDE_RS03840
uniprot id: Q21MU6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

203122:SDE RS16525
gene id: 203122:SDE_RS16525
uniprot id: Q21FW7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

203122:SDE RS02575
gene id: 203122:SDE_RS02575
uniprot id: Q21NJ3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family.
messages: Binds 1 Mg(2+) ion per subunit. Can also utilize other divalent metal cations, such as Ca(2+), Mn(2+) and Co(2+).
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
messages: Homodimer.

203122:SDE RS10405
gene id: 203122:SDE_RS10405
uniprot id: Q21J89
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily.

203122:SDE RS06775
gene id: 203122:SDE_RS06775
uniprot id: Q21L74
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

203122:SDE RS10825
gene id: 203122:SDE_RS10825
uniprot id: Q21J07
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

203122:SDE RS00655
gene id: 203122:SDE_RS00655
uniprot id: Q21PI9
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

203122:SDE RS14110
gene id: 203122:SDE_RS14110
uniprot id: Q21H72
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: Allosterically activated by HslU binding.
messages: Belongs to the peptidase T1B family. HslV subfamily.
messages: Cytoplasm
messages: Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.

203122:SDE RS00680
gene id: 203122:SDE_RS00680
uniprot id: Q21PI4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial sugar transferase family.
messages: Membrane

203122:SDE RS08535
gene id: 203122:SDE_RS08535
uniprot id: Q21K89
names: Similarity
messages: Belongs to the fabD family.

203122:SDE RS07375
gene id: 203122:SDE_RS07375
uniprot id: Q21KV9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell inner membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

203122:SDE RS07425
gene id: 203122:SDE_RS07425
uniprot id: Q21KV0
names: Function
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.
messages: Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine.

203122:SDE RS18865
gene id: 203122:SDE_RS18865
uniprot id: Q21EL3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

203122:SDE RS04755
gene id: 203122:SDE_RS04755
uniprot id: Q21MB3
names: Similarity
messages: Belongs to the gluconokinase GntK/GntV family.

203122:SDE RS12490
gene id: 203122:SDE_RS12490
uniprot id: Q21I34
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

203122:SDE RS16615
gene id: 203122:SDE_RS16615
uniprot id: Q21FU9
names: Subcellular Location Annotation
messages: Membrane

203122:SDE RS15160
gene id: 203122:SDE_RS15160
uniprot id: Q21GM2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

203122:SDE RS06640
gene id: 203122:SDE_RS06640
uniprot id: Q21LA1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

203122:SDE RS16260
gene id: 203122:SDE_RS16260
uniprot id: Q21G19
names: Function
names: Similarity
messages: Belongs to the CheD family.
messages: Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis.

203122:SDE RS06335
gene id: 203122:SDE_RS06335
uniprot id: Q21LG2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

203122:SDE RS07200
gene id: 203122:SDE_RS07200
uniprot id: Q21KZ3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptF/LptG family.
messages: Component of the lipopolysaccharide transport and assembly complex. The LptBFG transporter is composed of two ATP-binding proteins (LptB) and two transmembrane proteins (LptF and LptG).
messages: Membrane
messages: Part of the ABC transporter complex LptBFG involved in the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane.

203122:SDE RS16405
gene id: 203122:SDE_RS16405
uniprot id: Q21FZ0
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

203122:SDE RS08490
gene id: 203122:SDE_RS08490
uniprot id: Q21K98
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase E/G family. RNase E subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per homotetramer.
messages: Cell inner membrane
messages: Component of the RNA degradosome, which is a multiprotein complex involved in RNA processing and mRNA degradation. Within the RNA degradosome, RNase E assembles into a homotetramer formed by a dimer of dimers.
messages: Cytoplasm
messages: Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs.

203122:SDE RS10915
gene id: 203122:SDE_RS10915
uniprot id: Q21IZ0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

203122:SDE RS13100
gene id: 203122:SDE_RS13100
uniprot id: Q21HR5
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the xylose isomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.

203122:SDE RS06495
gene id: 203122:SDE_RS06495
uniprot id: Q21LD0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Cytoplasm
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
messages: The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.

203122:SDE RS06875
gene id: 203122:SDE_RS06875
uniprot id: Q21L56
names: Similarity
messages: Belongs to the BolA/IbaG family.

203122:SDE RS09310
gene id: 203122:SDE_RS09310
uniprot id: Q21JT9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal stress protein A family.
messages: Cytoplasm

203122:SDE RS08925
gene id: 203122:SDE_RS08925
uniprot id: Q21K13
names: Subcellular Location Annotation
messages: Membrane

203122:SDE RS17870
gene id: 203122:SDE_RS17870
uniprot id: Q21F56
names: Similarity
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.

203122:SDE RS17055
gene id: 203122:SDE_RS17055
uniprot id: Q21FL5
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

203122:SDE RS08230
gene id: 203122:SDE_RS08230
uniprot id: Q21KE5
names: Similarity
messages: Belongs to the glycosyl hydrolase 5 (cellulase A) family.

203122:SDE RS00265
gene id: 203122:SDE_RS00265
uniprot id: Q21PR4
names: Function
names: Similarity
messages: Belongs to the esterase D family.
messages: Serine hydrolase involved in the detoxification of formaldehyde.

203122:SDE RS09815
gene id: 203122:SDE_RS09815
uniprot id: Q21JJ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmE/CycJ family.
messages: Cell inner membrane
messages: Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH.

203122:SDE RS03705
gene id: 203122:SDE_RS03705
uniprot id: Q21MX1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

203122:SDE RS04210
gene id: 203122:SDE_RS04210
uniprot id: Q21MM2
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

203122:SDE RS06420
gene id: 203122:SDE_RS06420
uniprot id: Q21LE5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the spermidine/spermine synthase family.
messages: Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
messages: Cell membrane
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

203122:SDE RS21305
gene id: 203122:SDE_RS21305
uniprot id: Q21J99
names: Similarity
messages: Belongs to the transposase 7 family.

203122:SDE RS15210
gene id: 203122:SDE_RS15210
uniprot id: Q21GL4
names: Subcellular Location Annotation
messages: Membrane

203122:SDE RS08550
gene id: 203122:SDE_RS08550
uniprot id: Q21K86
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

203122:SDE RS12445
gene id: 203122:SDE_RS12445
uniprot id: Q21I43
names: Function
names: Similarity
messages: Belongs to the PurU family.
messages: Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).

203122:SDE RS13520
gene id: 203122:SDE_RS13520
uniprot id: Q21HI9
names: Similarity
messages: Belongs to the SUI1 family.

203122:SDE RS05750
gene id: 203122:SDE_RS05750
uniprot id: Q21LS0
names: Similarity
messages: Belongs to the GHMP kinase family. GalK subfamily.

203122:SDE RS03570
gene id: 203122:SDE_RS03570
uniprot id: Q21MZ8
names: Similarity
messages: Belongs to the SAICAR synthetase family.

203122:SDE RS14270
gene id: 203122:SDE_RS14270
uniprot id: Q21H42
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

203122:SDE RS14840
gene id: 203122:SDE_RS14840
uniprot id: Q21GT6
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

203122:SDE RS16555
gene id: 203122:SDE_RS16555
uniprot id: Q21FW1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome b family.
messages: Binds 1 heme c group covalently per subunit.
messages: Binds 2 heme groups non-covalently.
messages: Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.
messages: Membrane
messages: The main subunits of complex b-c1 are: cytochrome b, cytochrome c1 and the Rieske protein.

203122:SDE RS13590
gene id: 203122:SDE_RS13590
uniprot id: Q21HH5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

203122:SDE RS09160
gene id: 203122:SDE_RS09160
uniprot id: Q21JW9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
messages: Cell membrane
messages: Monomer.

203122:SDE RS13485
gene id: 203122:SDE_RS13485
uniprot id: Q21HJ6
names: Function
messages: Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).

203122:SDE RS11810
gene id: 203122:SDE_RS11810
uniprot id: Q21IG2
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

203122:SDE RS07150
gene id: 203122:SDE_RS07150
uniprot id: Q21L03
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

203122:SDE RS10080
gene id: 203122:SDE_RS10080
uniprot id: Q21JF0
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

203122:SDE RS11690
gene id: 203122:SDE_RS11690
uniprot id: Q21II6
names: Similarity
messages: Belongs to the KAE1 / TsaD family. TsaB subfamily.

203122:SDE RS12585
gene id: 203122:SDE_RS12585
uniprot id: Q21I15
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RnfG family.
messages: Cell inner membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

203122:SDE RS01860
gene id: 203122:SDE_RS01860
uniprot id: Q21NW4
names: Function
names: Similarity
messages: Belongs to the dihydrofolate reductase family.
messages: Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.

203122:SDE RS20850
gene id: 203122:SDE_RS20850
uniprot id: Q21DI5
names: Similarity
messages: Belongs to the CcdB toxin family.

203122:SDE RS19840
gene id: 203122:SDE_RS19840
uniprot id: Q21E27
names: Similarity
messages: Belongs to the bacterial sugar transferase family.

203122:SDE RS15630
gene id: 203122:SDE_RS15630
uniprot id: Q21GD3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Cell inner membrane
messages: Homoheptamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mechanosensitive channel that participates in the regulation of osmotic pressure changes within the cell, opening in response to stretch forces in the membrane lipid bilayer, without the need for other proteins. Contributes to normal resistance to hypoosmotic shock. Forms an ion channel of 1.0 nanosiemens conductance with a slight preference for anions.

203122:SDE RS11405
gene id: 203122:SDE_RS11405
uniprot id: Q21IP3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliL family.
messages: Cell inner membrane
messages: Controls the rotational direction of flagella during chemotaxis.
messages: Membrane

203122:SDE RS13565
gene id: 203122:SDE_RS13565
uniprot id: Q21HI0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamA family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

203122:SDE RS11565
gene id: 203122:SDE_RS11565
uniprot id: Q21IL0
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.

203122:SDE RS18060
gene id: 203122:SDE_RS18060
uniprot id: Q21F21
names: Caution
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the thiamine-monophosphate kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate.

203122:SDE RS07690
gene id: 203122:SDE_RS07690
uniprot id: Q21KP9
names: Similarity
messages: Belongs to the glucose-6-phosphate 1-epimerase family.

203122:SDE RS19640
gene id: 203122:SDE_RS19640
uniprot id: Q21E64
names: Subcellular Location Annotation
messages: Cytoplasm

203122:SDE RS01880
gene id: 203122:SDE_RS01880
uniprot id: Q21NW0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

203122:SDE RS01270
gene id: 203122:SDE_RS01270
uniprot id: Q21P75
names: Function
names: Similarity
messages: Belongs to the CobB/CobQ family. CobQ subfamily.
messages: Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation.

203122:SDE RS00225
gene id: 203122:SDE_RS00225
uniprot id: Q21PS2
names: Subcellular Location Annotation
messages: Membrane

203122:SDE RS09325
gene id: 203122:SDE_RS09325
uniprot id: Q21JT6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

203122:SDE RS00030
gene id: 203122:SDE_RS00030
uniprot id: Q21PV2
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Binds two Mg(2+) per subunit. The magnesium ions form salt bridges with both the protein and the DNA. Can also accept other divalent metal cations, such as Mn(2+) or Ca(2+).
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

203122:SDE RS05730
gene id: 203122:SDE_RS05730
uniprot id: Q21LS4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

203122:SDE RS19035
gene id: 203122:SDE_RS19035
uniprot id: Q21EI0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AB hydrolase superfamily. MetX family.
messages: Cytoplasm
messages: Homodimer.
messages: Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine.

203122:SDE RS21045
gene id: 203122:SDE_RS21045
uniprot id: Q21P49
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

203122:SDE RS10925
gene id: 203122:SDE_RS10925
uniprot id: Q21IY8
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

203122:SDE RS02660
gene id: 203122:SDE_RS02660
uniprot id: Q21NH6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

203122:SDE RS01840
gene id: 203122:SDE_RS01840
uniprot id: Q21NW8
names: Function
names: Similarity
messages: Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage.
messages: Belongs to the Nudix hydrolase family. RppH subfamily.

203122:SDE RS08365
gene id: 203122:SDE_RS08365
uniprot id: Q21KC1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. NspC subfamily.
messages: Catalyzes the decarboxylation of carboxynorspermidine and carboxyspermidine.
messages: Cytoplasm
messages: Homodimer.

203122:SDE RS19020
gene id: 203122:SDE_RS19020
uniprot id: Q21EI3
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

203122:SDE RS21695
gene id: 203122:SDE_RS21695
uniprot id: Q21DS9
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

203122:SDE RS08445
gene id: 203122:SDE_RS08445
uniprot id: Q21KA6
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

203122:SDE RS11995
gene id: 203122:SDE_RS11995
uniprot id: Q21IC5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

203122:SDE RS08520
gene id: 203122:SDE_RS08520
uniprot id: Q21K92
names: Function
names: Similarity
messages: Belongs to the DUF177 domain family.
messages: Plays a role in synthesis, processing and/or stability of 23S rRNA.

203122:SDE RS03085
gene id: 203122:SDE_RS03085
uniprot id: Q21N92
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

203122:SDE RS08700
gene id: 203122:SDE_RS08700
uniprot id: Q21K57
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YajC family.
messages: Cell inner membrane
messages: Membrane

203122:SDE RS19225
gene id: 203122:SDE_RS19225
uniprot id: Q21EE4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

203122:SDE RS16680
gene id: 203122:SDE_RS16680
uniprot id: Q21FT6
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.

203122:SDE RS13315
gene id: 203122:SDE_RS13315
uniprot id: Q21HN0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.

203122:SDE RS04900
gene id: 203122:SDE_RS04900
uniprot id: Q21M89
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

203122:SDE RS00295
gene id: 203122:SDE_RS00295
uniprot id: Q21PQ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

203122:SDE RS15925
gene id: 203122:SDE_RS15925
uniprot id: Q21G82
names: Cofactor
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. NagA family.
messages: Binds 1 divalent metal cation per subunit.

203122:SDE RS17285
gene id: 203122:SDE_RS17285
uniprot id: Q21FH2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

203122:SDE RS03920
gene id: 203122:SDE_RS03920
uniprot id: Q21MT0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

203122:SDE RS03905
gene id: 203122:SDE_RS03905
uniprot id: Q21MT3
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

203122:SDE RS07155
gene id: 203122:SDE_RS07155
uniprot id: Q21L02
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

203122:SDE RS20115
gene id: 203122:SDE_RS20115
uniprot id: Q21DX4
names: Similarity
messages: Belongs to the Gfa family.

203122:SDE RS13630
gene id: 203122:SDE_RS13630
uniprot id: Q21HG7
names: Activity Regulation
names: Caution
names: Domain
names: Similarity
messages: Belongs to the GlnD family.
messages: Has four distinct domains: an N-terminal nucleotidyltransferase (NT) domain responsible for UTase activity, a central HD domain that encodes UR activity, and two C-terminal ACT domains that seem to have a role in glutamine sensing.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Uridylyltransferase (UTase) activity is inhibited by glutamine, while glutamine activates uridylyl-removing (UR) activity.

203122:SDE RS03055
gene id: 203122:SDE_RS03055
uniprot id: Q21N99
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0316 family.
messages: Cell membrane

203122:SDE RS05635
gene id: 203122:SDE_RS05635
uniprot id: Q21LU2
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

203122:SDE RS17695
gene id: 203122:SDE_RS17695
uniprot id: Q21F91
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.
messages: Cell inner membrane
messages: Membrane
messages: Probable transporter of a GTP-driven Fe(2+) uptake system.

203122:SDE RS19195
gene id: 203122:SDE_RS19195
uniprot id: Q21EF0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the nucleoid occlusion factor SlmA family.
messages: Homodimer. Interacts with FtsZ.
messages: Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid. Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers. SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions.
messages: nucleoid

203122:SDE RS04855
gene id: 203122:SDE_RS04855
uniprot id: Q21M98
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

203122:SDE RS06290
gene id: 203122:SDE_RS06290
uniprot id: Q21LH1
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.

203122:SDE RS13045
gene id: 203122:SDE_RS13045
uniprot id: Q21HS5
names: Similarity
messages: Belongs to the glycosyl hydrolase 5 (cellulase A) family.

203122:SDE RS13785
gene id: 203122:SDE_RS13785
uniprot id: Q21HD6
names: Similarity
messages: Belongs to the glycosyl hydrolase 10 (cellulase F) family.

203122:SDE RS04450
gene id: 203122:SDE_RS04450
uniprot id: Q21MH4
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

203122:SDE RS08725
gene id: 203122:SDE_RS08725
uniprot id: Q21K52
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

203122:SDE RS00110
gene id: 203122:SDE_RS00110
uniprot id: Q21PV6
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

203122:SDE RS12345
gene id: 203122:SDE_RS12345
uniprot id: Q21I63
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

203122:SDE RS18065
gene id: 203122:SDE_RS18065
uniprot id: Q21F20
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

203122:SDE RS19745
gene id: 203122:SDE_RS19745
uniprot id: Q21E45
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arsenical resistance-3 (ACR3) (TC 2.A.59) family.
messages: Cell membrane
messages: Membrane

203122:SDE RS17575
gene id: 203122:SDE_RS17575
uniprot id: Q21FB4
names: Caution
names: Function
names: Similarity
messages: Belongs to the UbiX/PAD1 family.
messages: Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

203122:SDE RS19630
gene id: 203122:SDE_RS19630
uniprot id: Q21E66
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

203122:SDE RS03970
gene id: 203122:SDE_RS03970
uniprot id: Q21MS0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate synthase component I family.
messages: Heterotetramer consisting of two non-identical subunits: a beta subunit (TrpG) and a large alpha subunit (TrpE).
messages: Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia.

203122:SDE RS13885
gene id: 203122:SDE_RS13885
uniprot id: Q21HB7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

203122:SDE RS11520
gene id: 203122:SDE_RS11520
uniprot id: Q21IL9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

203122:SDE RS02585
gene id: 203122:SDE_RS02585
uniprot id: Q21NJ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RdgC family.
messages: May be involved in recombination.
messages: nucleoid

203122:SDE RS05245
gene id: 203122:SDE_RS05245
uniprot id: Q21M21
names: Caution
names: Function
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.

203122:SDE RS05145
gene id: 203122:SDE_RS05145
uniprot id: Q21M42
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

203122:SDE RS18725
gene id: 203122:SDE_RS18725
uniprot id: Q21EP1
names: Similarity
messages: Belongs to the glutamate--cysteine ligase type 1 family. Type 1 subfamily.

203122:SDE RS10375
gene id: 203122:SDE_RS10375
uniprot id: Q21J95
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 zinc ion per subunit.

203122:SDE RS13660
gene id: 203122:SDE_RS13660
uniprot id: Q21HG1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MoaC family.
messages: Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
messages: Homohexamer; trimer of dimers.

203122:SDE RS04460
gene id: 203122:SDE_RS04460
uniprot id: Q21MH2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell inner membrane

203122:SDE RS00235
gene id: 203122:SDE_RS00235
uniprot id: Q21PS0
names: Similarity
messages: Belongs to the SCO1/2 family.

203122:SDE RS11735
gene id: 203122:SDE_RS11735
uniprot id: Q21IH7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell inner membrane
messages: Cytoplasm
messages: Monomer.

203122:SDE RS14845
gene id: 203122:SDE_RS14845
uniprot id: Q21GT5
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

203122:SDE RS09775
gene id: 203122:SDE_RS09775
uniprot id: Q21JK7
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

203122:SDE RS06540
gene id: 203122:SDE_RS06540
uniprot id: Q21LC1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsB family.
messages: Cell inner membrane
messages: Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.
messages: Part of a complex composed of FtsB, FtsL and FtsQ.

203122:SDE RS12455
gene id: 203122:SDE_RS12455
uniprot id: Q21I41
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

203122:SDE RS01745
gene id: 203122:SDE_RS01745
uniprot id: Q21NY4
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the RtcB family.
messages: Binds 2 manganese ions per subunit.
messages: Monomer.

203122:SDE RS03880
gene id: 203122:SDE_RS03880
uniprot id: Q21MT8
names: Cofactor
names: Similarity
messages: Belongs to the DNA photolyase class-1 family.
messages: Belongs to the DNA photolyase family.
messages: Binds 1 FAD per subunit.

203122:SDE RS13825
gene id: 203122:SDE_RS13825
uniprot id: Q21HC9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

203122:SDE RS19660
gene id: 203122:SDE_RS19660
uniprot id: Q21E60
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

203122:SDE RS08400
gene id: 203122:SDE_RS08400
uniprot id: Q21KB4
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

203122:SDE RS02150
gene id: 203122:SDE_RS02150
uniprot id: Q21NQ6
names: Subcellular Location Annotation
messages: Membrane

203122:SDE RS18680
gene id: 203122:SDE_RS18680
uniprot id: Q21EQ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP J family.
messages: Cell inner membrane
messages: Membrane

203122:SDE RS01875
gene id: 203122:SDE_RS01875
uniprot id: Q21NW1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

203122:SDE RS03855
gene id: 203122:SDE_RS03855
uniprot id: Q21MU3
names: Function
names: Similarity
messages: Belongs to the HPPK family.
messages: Catalyzes the transfer of pyrophosphate from adenosine triphosphate (ATP) to 6-hydroxymethyl-7,8-dihydropterin, an enzymatic step in folate biosynthesis pathway.

203122:SDE RS12950
gene id: 203122:SDE_RS12950
uniprot id: Q21HU3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

203122:SDE RS17865
gene id: 203122:SDE_RS17865
uniprot id: Q21F57
names: Similarity
messages: Belongs to the YciI family.

203122:SDE RS17160
gene id: 203122:SDE_RS17160
uniprot id: Q21FJ6
names: Similarity
messages: Belongs to the FBPase class 3 family.

203122:SDE RS00465
gene id: 203122:SDE_RS00465
uniprot id: Q21PM4
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

203122:SDE RS07415
gene id: 203122:SDE_RS07415
uniprot id: Q21KV2
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

203122:SDE RS15460
gene id: 203122:SDE_RS15460
uniprot id: Q21GG6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

203122:SDE RS01740
gene id: 203122:SDE_RS01740
uniprot id: Q21NY5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

203122:SDE RS05835
gene id: 203122:SDE_RS05835
uniprot id: Q21LQ7
names: Similarity
messages: Belongs to the MlaA family.

203122:SDE RS03410
gene id: 203122:SDE_RS03410
uniprot id: Q21N30
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LysR transcriptional regulatory family.
messages: Cytoplasm

203122:SDE RS04115
gene id: 203122:SDE_RS04115
uniprot id: Q21MP1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:galactoside symporter (TC 2.A.2) family.
messages: Membrane

203122:SDE RS14010
gene id: 203122:SDE_RS14010
uniprot id: Q21H92
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

203122:SDE RS03405
gene id: 203122:SDE_RS03405
uniprot id: Q21N31
names: Similarity
messages: Belongs to the glycosyl hydrolase 9 (cellulase E) family.

203122:SDE RS16860
gene id: 203122:SDE_RS16860
uniprot id: Q21FP9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRA-PH family.
messages: Cytoplasm

203122:SDE RS10795
gene id: 203122:SDE_RS10795
uniprot id: Q21J13
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

203122:SDE RS10250
gene id: 203122:SDE_RS10250
uniprot id: Q21JC0
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Member of a two-component regulatory system.

203122:SDE RS08410
gene id: 203122:SDE_RS08410
uniprot id: Q21KB2
names: Similarity
messages: In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family.

203122:SDE RS08455
gene id: 203122:SDE_RS08455
uniprot id: Q21KA4
names: Function
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.
messages: Provides the (R)-glutamate required for cell wall biosynthesis.

203122:SDE RS03580
gene id: 203122:SDE_RS03580
uniprot id: Q21MZ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

203122:SDE RS07120
gene id: 203122:SDE_RS07120
uniprot id: Q21L09
names: Subcellular Location Annotation
messages: Membrane

203122:SDE RS07905
gene id: 203122:SDE_RS07905
uniprot id: Q21KK9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

203122:SDE RS09720
gene id: 203122:SDE_RS09720
uniprot id: Q21JL8
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

203122:SDE RS12070
gene id: 203122:SDE_RS12070
uniprot id: Q21IA9
names: Similarity
messages: Belongs to the AHA1 family.

203122:SDE RS19780
gene id: 203122:SDE_RS19780
uniprot id: Q21E38
names: Function
names: Similarity
messages: Belongs to the CsgG family.
messages: May be involved in the biogenesis of curli organelles.

203122:SDE RS01195
gene id: 203122:SDE_RS01195
uniprot id: Q21P91
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SIMIBI class G3E GTPase family. UreG subfamily.
messages: Cytoplasm
messages: Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG.
messages: Homodimer. UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

203122:SDE RS19090
gene id: 203122:SDE_RS19090
uniprot id: Q21EG9
names: Similarity
messages: Belongs to the thioredoxin family.

203122:SDE RS14995
gene id: 203122:SDE_RS14995
uniprot id: Q21GQ6
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

203122:SDE RS11325
gene id: 203122:SDE_RS11325
uniprot id: Q21IQ8
names: Function
messages: Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors. CheA is autophosphorylated; it can transfer its phosphate group to either CheB or CheY.

203122:SDE RS19800
gene id: 203122:SDE_RS19800
uniprot id: Q21E34
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

203122:SDE RS19975
gene id: 203122:SDE_RS19975
uniprot id: Q21E00
names: Similarity
messages: Belongs to the UPF0246 family.

203122:SDE RS19285
gene id: 203122:SDE_RS19285
uniprot id: Q21ED3
names: Similarity
messages: Belongs to the glycosyl hydrolase 26 family.

203122:SDE RS07490
gene id: 203122:SDE_RS07490
uniprot id: Q21KT7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

203122:SDE RS13330
gene id: 203122:SDE_RS13330
uniprot id: Q21HM7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

203122:SDE RS17165
gene id: 203122:SDE_RS17165
uniprot id: Q21FJ5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class II fructose-bisphosphate aldolase family.
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.
messages: Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.

203122:SDE RS00070
gene id: 203122:SDE_RS00070
uniprot id: Q21PU4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

203122:SDE RS07525
gene id: 203122:SDE_RS07525
uniprot id: Q21KT0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamB family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

203122:SDE RS08975
gene id: 203122:SDE_RS08975
uniprot id: Q21K03
names: Similarity
messages: Belongs to the YciI family.

203122:SDE RS13790
gene id: 203122:SDE_RS13790
uniprot id: Q21HD5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

203122:SDE RS21420
gene id: 203122:SDE_RS21420
uniprot id: Q21GU5
names: Similarity
messages: Belongs to the glycosyl hydrolase 53 family.

203122:SDE RS17770
gene id: 203122:SDE_RS17770
uniprot id: Q21F76
names: Cofactor
messages: Binds 1 phosphopantetheine covalently.

203122:SDE RS16265
gene id: 203122:SDE_RS16265
uniprot id: Q21G18
names: Function
messages: Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP.

203122:SDE RS08440
gene id: 203122:SDE_RS08440
uniprot id: Q21KA7
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

203122:SDE RS00355
gene id: 203122:SDE_RS00355
uniprot id: Q21PP5
names: Subcellular Location Annotation
messages: Membrane

203122:SDE RS10920
gene id: 203122:SDE_RS10920
uniprot id: Q21IY9
names: Similarity
messages: Belongs to the TrpF family.

203122:SDE RS08845
gene id: 203122:SDE_RS08845
uniprot id: Q21K28
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L/F-transferase family.
messages: Cytoplasm
messages: Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.

203122:SDE RS13965
gene id: 203122:SDE_RS13965
uniprot id: Q21HA1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Monomer.

203122:SDE RS04495
gene id: 203122:SDE_RS04495
uniprot id: Q21MG5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.
messages: Cell inner membrane
messages: Self-interacts. Interacts with FtsZ.

203122:SDE RS11225
gene id: 203122:SDE_RS11225
uniprot id: Q21IS8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the OMP decarboxylase family. Type 1 subfamily.
messages: Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
messages: Homodimer.

203122:SDE RS01165
gene id: 203122:SDE_RS01165
uniprot id: Q21P97
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UreD family.
messages: Cytoplasm
messages: Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
messages: UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

203122:SDE RS18715
gene id: 203122:SDE_RS18715
uniprot id: Q21EP3
names: Similarity
messages: Belongs to the GSP C family.

203122:SDE RS06905
gene id: 203122:SDE_RS06905
uniprot id: Q21L50
names: Subcellular Location Annotation
messages: Membrane

203122:SDE RS12825
gene id: 203122:SDE_RS12825
uniprot id: Q21HW8
names: Similarity
messages: Belongs to the thioesterase family.

203122:SDE RS05255
gene id: 203122:SDE_RS05255
uniprot id: Q21M19
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

203122:SDE RS17915
gene id: 203122:SDE_RS17915
uniprot id: Q21F48
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

203122:SDE RS18995
gene id: 203122:SDE_RS18995
uniprot id: Q21EI8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

203122:SDE RS20805
gene id: 203122:SDE_RS20805
uniprot id: Q21DJ4
names: Similarity
messages: Belongs to the fructosamine kinase family.

203122:SDE RS19730
gene id: 203122:SDE_RS19730
uniprot id: Q21E48
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

203122:SDE RS12130
gene id: 203122:SDE_RS12130
uniprot id: Q21I98
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

203122:SDE RS19210
gene id: 203122:SDE_RS19210
uniprot id: Q21EE7
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

203122:SDE RS00485
gene id: 203122:SDE_RS00485
uniprot id: Q21PM0
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

203122:SDE RS15675
gene id: 203122:SDE_RS15675
uniprot id: Q21GC4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

203122:SDE RS06880
gene id: 203122:SDE_RS06880
uniprot id: Q21L55
names: Function
names: Similarity
messages: Belongs to the TrhO family.
messages: Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs.

203122:SDE RS08880
gene id: 203122:SDE_RS08880
uniprot id: Q21K21
names: Function
names: Similarity
messages: In the C-terminal section; belongs to the precorrin methyltransferase family.
messages: In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family.
messages: Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme.

203122:SDE RS20290
gene id: 203122:SDE_RS20290
uniprot id: Q21DU4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

203122:SDE RS16565
gene id: 203122:SDE_RS16565
uniprot id: Q21FV9
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

203122:SDE RS04290
gene id: 203122:SDE_RS04290
uniprot id: Q21MK6
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

203122:SDE RS18820
gene id: 203122:SDE_RS18820
uniprot id: Q21EM2
names: Subcellular Location Annotation
messages: Membrane

203122:SDE RS05210
gene id: 203122:SDE_RS05210
uniprot id: Q21M27
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
messages: Homotetramer.
messages: Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc.

203122:SDE RS03925
gene id: 203122:SDE_RS03925
uniprot id: Q21MS9
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PdxA family.
messages: Binds 1 divalent metal cation per subunit. Can use ions such as Zn(2+), Mg(2+) or Co(2+).
messages: Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L-threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP).
messages: Cytoplasm
messages: Homodimer.
messages: The active site is located at the dimer interface.

203122:SDE RS11265
gene id: 203122:SDE_RS11265
uniprot id: Q21IS0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. MTA/SAH deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L-homocysteine, respectively. Is also able to deaminate adenosine.

203122:SDE RS14305
gene id: 203122:SDE_RS14305
uniprot id: Q21H36
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

203122:SDE RS04330
gene id: 203122:SDE_RS04330
uniprot id: Q21MJ8
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.

203122:SDE RS05265
gene id: 203122:SDE_RS05265
uniprot id: Q21M17
names: Similarity
messages: Belongs to the UDPGP type 2 family.

203122:SDE RS10480
gene id: 203122:SDE_RS10480
uniprot id: Q21J74
names: Cofactor
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.
messages: Probably binds two magnesium or manganese ions per subunit.

203122:SDE RS15135
gene id: 203122:SDE_RS15135
uniprot id: Q21GM7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Cell inner membrane
messages: Homoheptamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mechanosensitive channel that participates in the regulation of osmotic pressure changes within the cell, opening in response to stretch forces in the membrane lipid bilayer, without the need for other proteins. Contributes to normal resistance to hypoosmotic shock. Forms an ion channel of 1.0 nanosiemens conductance with a slight preference for anions.

203122:SDE RS17680
gene id: 203122:SDE_RS17680
uniprot id: Q21F94
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PEPCase type 1 family.
messages: Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.
messages: Homotetramer.

203122:SDE RS13220
gene id: 203122:SDE_RS13220
uniprot id: Q21HP4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the QueC family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).

203122:SDE RS10780
gene id: 203122:SDE_RS10780
uniprot id: Q21J16
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

203122:SDE RS19230
gene id: 203122:SDE_RS19230
uniprot id: Q21EE3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FPG family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
messages: Monomer.

203122:SDE RS21055
gene id: 203122:SDE_RS21055
uniprot id: Q21P16
names: Similarity
messages: Belongs to the peptidase S8 family.

203122:SDE RS10165
gene id: 203122:SDE_RS10165
uniprot id: Q21JD7
names: Subcellular Location Annotation
messages: Membrane

203122:SDE RS11390
gene id: 203122:SDE_RS11390
uniprot id: Q21IP6
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliO/MopB family.
messages: Cell membrane

203122:SDE RS09405
gene id: 203122:SDE_RS09405
uniprot id: Q21JS0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrC family.
messages: Cell inner membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

203122:SDE RS20740
gene id: 203122:SDE_RS20740
uniprot id: Q21DK6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

203122:SDE RS05170
gene id: 203122:SDE_RS05170
uniprot id: Q21M35
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

203122:SDE RS05185
gene id: 203122:SDE_RS05185
uniprot id: Q21M32
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

203122:SDE RS11820
gene id: 203122:SDE_RS11820
uniprot id: Q21IG0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MobA family.
messages: Cytoplasm
messages: Monomer.
messages: The N-terminal domain determines nucleotide recognition and specific binding, while the C-terminal domain determines the specific binding to the target protein.
messages: Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor.

203122:SDE RS12970
gene id: 203122:SDE_RS12970
uniprot id: Q21HT9
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

203122:SDE RS10490
gene id: 203122:SDE_RS10490
uniprot id: Q21J72
names: Cofactor
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.
messages: Binds 1 FAD per dimer.

203122:SDE RS11930
gene id: 203122:SDE_RS11930
uniprot id: Q21ID8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

203122:SDE RS05095
gene id: 203122:SDE_RS05095
uniprot id: Q21M51
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

203122:SDE RS17190
gene id: 203122:SDE_RS17190
uniprot id: Q21FJ0
names: Biotechnology
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the polysaccharide lyase 17 family.
messages: Catalyzes the depolymerization of alginate through an exolytic mode of action, via a beta-elimination mechanism. Preferentially acts on oligoalginates with degrees of polymerization higher than 2 to produce the alginate monomer, 4-deoxy-L-erythro-5-hexoseulose uronic acid.
messages: Could be used as the key enzyme to produce alginate monomers in the process of utilizing alginate for biofuels and chemicals production.
messages: Homodimer.
messages: Periplasm
messages: The zinc ion seen in the crystal structure is located far away from the active site and likely plays a structural role. However, it seems important for enzyme activity since the mutation of one of its coordination residues causes a high decrease in activity.

203122:SDE RS04650
gene id: 203122:SDE_RS04650
uniprot id: Q21MD4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

203122:SDE RS13870
gene id: 203122:SDE_RS13870
uniprot id: Q21HC0
names: Subcellular Location Annotation
messages: Membrane

203122:SDE RS07470
gene id: 203122:SDE_RS07470
uniprot id: Q21KU1
names: Subcellular Location Annotation
messages: Membrane

203122:SDE RS13200
gene id: 203122:SDE_RS13200
uniprot id: Q21HP6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Homodimer.

203122:SDE RS16835
gene id: 203122:SDE_RS16835
uniprot id: Q21FQ4
names: Similarity
messages: Belongs to the MotB family.

203122:SDE RS11685
gene id: 203122:SDE_RS11685
uniprot id: Q21II7
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell inner membrane

203122:SDE RS03495
gene id: 203122:SDE_RS03495
uniprot id: Q21N13
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Homooctamer.

203122:SDE RS04895
gene id: 203122:SDE_RS04895
uniprot id: Q21M90
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

203122:SDE RS06765
gene id: 203122:SDE_RS06765
uniprot id: Q21L76
names: Subcellular Location Annotation
messages: Membrane

203122:SDE RS16560
gene id: 203122:SDE_RS16560
uniprot id: Q21FW0
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Rieske iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.
messages: Membrane
messages: The Rieske protein is a high potential 2Fe-2S protein.
messages: The main subunits of complex b-c1 are: cytochrome b, cytochrome c1 and the Rieske protein.

203122:SDE RS13270
gene id: 203122:SDE_RS13270
uniprot id: Q21HN4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvC family.
messages: Binds 2 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer which binds Holliday junction (HJ) DNA. The HJ becomes 2-fold symmetrical on binding to RuvC with unstacked arms; it has a different conformation from HJ DNA in complex with RuvA. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair. Endonuclease that resolves HJ intermediates. Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction. The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'. Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange. HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

203122:SDE RS09860
gene id: 203122:SDE_RS09860
uniprot id: Q21JJ2
names: Function
names: Similarity
messages: Belongs to the CcmH/CycL/Ccl2/NrfF family.
messages: Possible subunit of a heme lyase.

203122:SDE RS05665
gene id: 203122:SDE_RS05665
uniprot id: Q21LT6
names: Similarity
messages: Belongs to the radical SAM superfamily. KamA family.

203122:SDE RS17630
gene id: 203122:SDE_RS17630
uniprot id: Q21FA3
names: Similarity
messages: Belongs to the SfsA family.

203122:SDE RS11315
gene id: 203122:SDE_RS11315
uniprot id: Q21IR0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

203122:SDE RS01550
gene id: 203122:SDE_RS01550
uniprot id: Q21P23
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

203122:SDE RS13700
gene id: 203122:SDE_RS13700
uniprot id: Q21HF3
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

203122:SDE RS15870
gene id: 203122:SDE_RS15870
uniprot id: Q21G92
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

203122:SDE RS05260
gene id: 203122:SDE_RS05260
uniprot id: Q21M18
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thioester dehydratase family. FabA subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)-decenoyl-ACP. Can catalyze the dehydratase reaction for beta-hydroxyacyl-ACPs with saturated chain lengths up to 16:0, being most active on intermediate chain length.

203122:SDE RS04675
gene id: 203122:SDE_RS04675
uniprot id: Q21MC9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I fumarase family.
messages: Catalyzes the reversible hydration of fumarate to (S)-malate.
messages: Homodimer.

203122:SDE RS05140
gene id: 203122:SDE_RS05140
uniprot id: Q21M43
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

203122:SDE RS02050
gene id: 203122:SDE_RS02050
uniprot id: Q21NS6
names: Function
names: Similarity
messages: Belongs to the GlnE family.
messages: Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell.

203122:SDE RS19160
gene id: 203122:SDE_RS19160
uniprot id: Q21EF7
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HMBS family.
messages: Binds 1 dipyrromethane group covalently.
messages: Monomer.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
messages: The porphobilinogen subunits are added to the dipyrromethane group.

203122:SDE RS07795
gene id: 203122:SDE_RS07795
uniprot id: Q21KM8
names: Similarity
messages: Belongs to the helicase family. RecQ subfamily.

203122:SDE RS03415
gene id: 203122:SDE_RS03415
uniprot id: Q21N29
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 independent methionine synthase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine resulting in methionine formation.

203122:SDE RS04810
gene id: 203122:SDE_RS04810
uniprot id: Q21MA2
names: Function
names: Similarity
messages: Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon.
messages: Belongs to the biotin--protein ligase family.

203122:SDE RS04995
gene id: 203122:SDE_RS04995
uniprot id: Q21M71
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

203122:SDE RS04630
gene id: 203122:SDE_RS04630
uniprot id: Q21MD8
names: Subcellular Location Annotation
messages: Membrane

203122:SDE RS05535
gene id: 203122:SDE_RS05535
uniprot id: Q21LW2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. RlmB subfamily.
messages: Cytoplasm
messages: Specifically methylates the ribose of guanosine 2251 in 23S rRNA.

203122:SDE RS03100
gene id: 203122:SDE_RS03100
uniprot id: Q21N89
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Membrane

203122:SDE RS18095
gene id: 203122:SDE_RS18095
uniprot id: Q21F14
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.
messages: Binds 2 iron ions per subunit.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

203122:SDE RS02690
gene id: 203122:SDE_RS02690
uniprot id: Q21NH1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the BPG-independent phosphoglycerate mutase family.
messages: Binds 2 manganese ions per subunit.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: Monomer.

203122:SDE RS11185
gene id: 203122:SDE_RS11185
uniprot id: Q21IT6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. WecA subfamily.
messages: Catalyzes the transfer of the GlcNAc-1-phosphate moiety from UDP-GlcNAc onto the carrier lipid undecaprenyl phosphate (C55-P), yielding GlcNAc-pyrophosphoryl-undecaprenyl (GlcNAc-PP-C55).
messages: Cell inner membrane
messages: Membrane

203122:SDE RS01820
gene id: 203122:SDE_RS01820
uniprot id: Q21NX2
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

203122:SDE RS20035
gene id: 203122:SDE_RS20035
uniprot id: Q21DY9
names: Subcellular Location Annotation
messages: Membrane

203122:SDE RS11455
gene id: 203122:SDE_RS11455
uniprot id: Q21IN3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliH family.
messages: Cytoplasm
messages: Needed for flagellar regrowth and assembly.

203122:SDE RS08555
gene id: 203122:SDE_RS08555
uniprot id: Q21K85
names: Subunit
messages: Homodimer.

203122:SDE RS17280
gene id: 203122:SDE_RS17280
uniprot id: Q21FH3
names: Similarity
messages: Belongs to the PhoH family.

203122:SDE RS12555
gene id: 203122:SDE_RS12555
uniprot id: Q21I21
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.

203122:SDE RS12700
gene id: 203122:SDE_RS12700
uniprot id: Q21HZ3
names: Similarity
messages: Belongs to the UPF0502 family.

203122:SDE RS19050
gene id: 203122:SDE_RS19050
uniprot id: Q21EH7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

203122:SDE RS03670
gene id: 203122:SDE_RS03670
uniprot id: Q21MX8
names: Similarity
messages: Belongs to the thioester dehydratase family. FabA subfamily.
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

203122:SDE RS13535
gene id: 203122:SDE_RS13535
uniprot id: Q21HI6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

203122:SDE RS05550
gene id: 203122:SDE_RS05550
uniprot id: Q21LV9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein bS6.

203122:SDE RS09410
gene id: 203122:SDE_RS09410
uniprot id: Q21JR9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell inner membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: Membrane
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

203122:SDE RS11180
gene id: 203122:SDE_RS11180
uniprot id: Q21IT7
names: Subcellular Location Annotation
messages: Membrane

203122:SDE RS04690
gene id: 203122:SDE_RS04690
uniprot id: Q21MC6
names: Similarity
messages: Belongs to the pterin-4-alpha-carbinolamine dehydratase family.

203122:SDE RS21380
gene id: 203122:SDE_RS21380
uniprot id: Q21HF5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane
messages: Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins.

203122:SDE RS07390
gene id: 203122:SDE_RS07390
uniprot id: Q21KV7
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

203122:SDE RS11270
gene id: 203122:SDE_RS11270
uniprot id: Q21IR9
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily. UbiG/COQ3 family.
messages: O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway.

203122:SDE RS05180
gene id: 203122:SDE_RS05180
uniprot id: Q21M33
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

203122:SDE RS04705
gene id: 203122:SDE_RS04705
uniprot id: Q21MC3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

203122:SDE RS00340
gene id: 203122:SDE_RS00340
uniprot id: Q21PP9
names: Similarity
names: Subunit
messages: Belongs to the RNase H family.
messages: Monomer.

203122:SDE RS07430
gene id: 203122:SDE_RS07430
uniprot id: Q21KU9
names: Similarity
messages: Belongs to the HesB/IscA family.

203122:SDE RS04875
gene id: 203122:SDE_RS04875
uniprot id: Q21M94
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

203122:SDE RS01935
gene id: 203122:SDE_RS01935
uniprot id: Q21NU9
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

203122:SDE RS14815
gene id: 203122:SDE_RS14815
uniprot id: Q21GU1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

203122:SDE RS02955
gene id: 203122:SDE_RS02955
uniprot id: Q21NB9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

203122:SDE RS20050
gene id: 203122:SDE_RS20050
uniprot id: Q21DY6
names: Function
messages: This protein is a positive regulator for the phosphate regulon. Transcription of this operon is positively regulated by PhoB and PhoR when phosphate is limited.

203122:SDE RS20020
gene id: 203122:SDE_RS20020
uniprot id: Q21DZ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

203122:SDE RS06325
gene id: 203122:SDE_RS06325
uniprot id: Q21LG4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

203122:SDE RS03210
gene id: 203122:SDE_RS03210
uniprot id: Q21N67
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

203122:SDE RS13255
gene id: 203122:SDE_RS13255
uniprot id: Q21HN7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ExbB/TolQ family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

203122:SDE RS07190
gene id: 203122:SDE_RS07190
uniprot id: Q21KZ5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M17 family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm
messages: Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.

203122:SDE RS04860
gene id: 203122:SDE_RS04860
uniprot id: Q21M97
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

203122:SDE RS21005
gene id: 203122:SDE_RS21005
uniprot id: Q21PN8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbA subfamily.
messages: Periplasm

203122:SDE RS18695
gene id: 203122:SDE_RS18695
uniprot id: Q21EP7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP G family.
messages: Cell inner membrane
messages: Membrane

203122:SDE RS13945
gene id: 203122:SDE_RS13945
uniprot id: Q21HA5
names: Function
names: Similarity
messages: Belongs to the band 7/mec-2 family. HflC subfamily.
messages: HflC and HflK could regulate a protease.

203122:SDE RS19680
gene id: 203122:SDE_RS19680
uniprot id: Q21E56
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

203122:SDE RS04940
gene id: 203122:SDE_RS04940
uniprot id: Q21M82
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphofructokinase type A (PFKA) family. PPi-dependent PFK group II subfamily. Clade 'B2' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Non-allosteric.

203122:SDE RS18700
gene id: 203122:SDE_RS18700
uniprot id: Q21EP6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Cell inner membrane
messages: Component of the type II secretion system inner membrane complex required for the energy-dependent secretion of extracellular factors such as proteases and toxins from the periplasm.
messages: Membrane

203122:SDE RS15730
gene id: 203122:SDE_RS15730
uniprot id: Q21GB5
names: Similarity
messages: Belongs to the polysaccharide lyase 3 family.

203122:SDE RS19320
gene id: 203122:SDE_RS19320
uniprot id: Q21EC6
names: Similarity
messages: Belongs to the RutC family.

203122:SDE RS02205
gene id: 203122:SDE_RS02205
uniprot id: Q21NP5
names: Subcellular Location Annotation
messages: Membrane

203122:SDE RS14765
gene id: 203122:SDE_RS14765
uniprot id: Q21GV1
names: Similarity
messages: Belongs to the elongation factor P family.

203122:SDE RS13360
gene id: 203122:SDE_RS13360
uniprot id: Q21HM1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.

203122:SDE RS09820
gene id: 203122:SDE_RS09820
uniprot id: Q21JJ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmF/CycK/Ccl1/NrfE/CcsA family.
messages: Cell inner membrane
messages: Membrane

203122:SDE RS02135
gene id: 203122:SDE_RS02135
uniprot id: Q21NQ9
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

203122:SDE RS10395
gene id: 203122:SDE_RS10395
uniprot id: Q21J91
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

203122:SDE RS00755
gene id: 203122:SDE_RS00755
uniprot id: Q21PG9
names: Similarity
messages: Belongs to the asparagine synthetase family.

203122:SDE RS09375
gene id: 203122:SDE_RS09375
uniprot id: Q21JS6
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Although this enzyme belongs to the family of MTA phosphorylases based on sequence homology, it has been shown that conserved amino acid substitutions in the substrate binding pocket convert the substrate specificity of this enzyme from 6-aminopurines to 6-oxopurines.
messages: Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily.
messages: Homohexamer. Dimer of a homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Purine nucleoside phosphorylase which is highly specific for 6-oxopurine nucleosides. Cleaves guanosine or inosine to respective bases and sugar-1-phosphate molecules. Involved in purine salvage.

203122:SDE RS21470
gene id: 203122:SDE_RS21470
uniprot id: Q21GD0
names: Similarity
messages: Belongs to the glycosyl hydrolase 30 family.

203122:SDE RS14395
gene id: 203122:SDE_RS14395
uniprot id: Q21H18
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

203122:SDE RS07510
gene id: 203122:SDE_RS07510
uniprot id: Q21KT3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

203122:SDE RS14740
gene id: 203122:SDE_RS14740
uniprot id: Q21GV6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

203122:SDE RS17045
gene id: 203122:SDE_RS17045
uniprot id: Q21FL7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

203122:SDE RS16345
gene id: 203122:SDE_RS16345
uniprot id: Q21G02
names: Subcellular Location Annotation
messages: Cell inner membrane

203122:SDE RS07960
gene id: 203122:SDE_RS07960
uniprot id: Q21KJ9
names: Similarity
messages: Belongs to the CvfB family.

203122:SDE RS01210
gene id: 203122:SDE_RS01210
uniprot id: Q21P88
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

203122:SDE RS12580
gene id: 203122:SDE_RS12580
uniprot id: Q21I16
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrB/RnfD family.
messages: Cell inner membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

203122:SDE RS09200
gene id: 203122:SDE_RS09200
uniprot id: Q21JW1
names: Subcellular Location Annotation
messages: Membrane

203122:SDE RS02885
gene id: 203122:SDE_RS02885
uniprot id: Q21ND2
names: Similarity
messages: Belongs to the UPF0234 family.

203122:SDE RS15545
gene id: 203122:SDE_RS15545
uniprot id: Q21GE9
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

203122:SDE RS16255
gene id: 203122:SDE_RS16255
uniprot id: Q21G20
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CheB family.
messages: Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.
messages: Cytoplasm
messages: Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
messages: Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity.

203122:SDE RS06310
gene id: 203122:SDE_RS06310
uniprot id: Q21LG7
names: Subcellular Location Annotation
messages: Membrane

203122:SDE RS05885
gene id: 203122:SDE_RS05885
uniprot id: Q21LP7
names: Subcellular Location Annotation
messages: Cytoplasm

203122:SDE RS04260
gene id: 203122:SDE_RS04260
uniprot id: Q21ML2
names: Similarity
messages: Belongs to the GARS family.

203122:SDE RS08275
gene id: 203122:SDE_RS08275
uniprot id: Q21KD8
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

203122:SDE RS08765
gene id: 203122:SDE_RS08765
uniprot id: Q21K44
names: Function
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
messages: Catalyzes two reactions in de novo purine nucleotide biosynthesis. Catalyzes the breakdown of 5-aminoimidazole- (N-succinylocarboxamide) ribotide (SAICAR or 2-[5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamido]succinate) to 5-aminoimidazole-4-carboxamide ribotide (AICAR or 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide) and fumarate, and of adenylosuccinate (ADS or N(6)-(1,2-dicarboxyethyl)-AMP) to adenosine monophosphate (AMP) and fumarate.

203122:SDE RS17790
gene id: 203122:SDE_RS17790
uniprot id: Q21F72
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

203122:SDE RS08525
gene id: 203122:SDE_RS08525
uniprot id: Q21K91
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

203122:SDE RS07165
gene id: 203122:SDE_RS07165
uniprot id: Q21L00
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein PotD/PotF family.
messages: Periplasm
messages: Required for the activity of the bacterial periplasmic transport system of putrescine.

203122:SDE RS16940
gene id: 203122:SDE_RS16940
uniprot id: Q21FN3
names: Similarity
messages: Belongs to the glycosyl hydrolase 5 (cellulase A) family.

203122:SDE RS05085
gene id: 203122:SDE_RS05085
uniprot id: Q21M53
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

203122:SDE RS10875
gene id: 203122:SDE_RS10875
uniprot id: Q21IZ8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the trans-sulfuration enzymes family. MetZ subfamily.
messages: Catalyzes the formation of L-homocysteine from O-succinyl-L-homoserine (OSHS) and hydrogen sulfide.
messages: Homotetramer.

203122:SDE RS04430
gene id: 203122:SDE_RS04430
uniprot id: Q21MH8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MraZ family.
messages: Forms oligomers.
messages: nucleoid

203122:SDE RS10885
gene id: 203122:SDE_RS10885
uniprot id: Q21IZ6
names: Subcellular Location Annotation
messages: Membrane

203122:SDE RS03760
gene id: 203122:SDE_RS03760
uniprot id: Q21MW0
names: Similarity
messages: Belongs to the Gfa family.

203122:SDE RS10360
gene id: 203122:SDE_RS10360
uniprot id: Q21J98
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

203122:SDE RS07305
gene id: 203122:SDE_RS07305
uniprot id: Q21KX2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:galactoside symporter (TC 2.A.2) family.
messages: Membrane

203122:SDE RS02735
gene id: 203122:SDE_RS02735
uniprot id: Q21NG2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThiI family.
messages: Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.
messages: Cytoplasm

203122:SDE RS04095
gene id: 203122:SDE_RS04095
uniprot id: Q21MP5
names: Similarity
messages: Belongs to the ribulokinase family.

203122:SDE RS06735
gene id: 203122:SDE_RS06735
uniprot id: Q21L82
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

203122:SDE RS21035
gene id: 203122:SDE_RS21035
uniprot id: Q21PB7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the XseA family.
messages: Cytoplasm

203122:SDE RS03035
gene id: 203122:SDE_RS03035
uniprot id: Q21NA4
names: Similarity
messages: Belongs to the MlaA family.

203122:SDE RS10880
gene id: 203122:SDE_RS10880
uniprot id: Q21IZ7
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

203122:SDE RS12600
gene id: 203122:SDE_RS12600
uniprot id: Q21I12
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

203122:SDE RS17640
gene id: 203122:SDE_RS17640
uniprot id: Q21FA1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. GluQ subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5-dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon.

203122:SDE RS14165
gene id: 203122:SDE_RS14165
uniprot id: Q21H61
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

203122:SDE RS14290
gene id: 203122:SDE_RS14290
uniprot id: Q21H39
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

203122:SDE RS16420
gene id: 203122:SDE_RS16420
uniprot id: Q21FY7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dethiobiotin synthetase family.
messages: Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

203122:SDE RS13235
gene id: 203122:SDE_RS13235
uniprot id: Q21HP1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Pal lipoprotein family.
messages: Cell outer membrane
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

203122:SDE RS00665
gene id: 203122:SDE_RS00665
uniprot id: Q21PI7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

203122:SDE RS18075
gene id: 203122:SDE_RS18075
uniprot id: Q21F18
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DHBP synthase family.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Homodimer.
messages: In the C-terminal section; belongs to the GTP cyclohydrolase II family.
messages: In the N-terminal section; belongs to the DHBP synthase family.

203122:SDE RS04345
gene id: 203122:SDE_RS04345
uniprot id: Q21MJ5
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

203122:SDE RS05530
gene id: 203122:SDE_RS05530
uniprot id: Q21LW3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.
messages: Belongs to the RNR ribonuclease family. RNase R subfamily.
messages: Cytoplasm

203122:SDE RS03120
gene id: 203122:SDE_RS03120
uniprot id: Q21N85
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

203122:SDE RS05935
gene id: 203122:SDE_RS05935
uniprot id: Q21LN7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S-adenosyl-L-methionine to the 2'-OH of the wobble nucleotide.

203122:SDE RS16435
gene id: 203122:SDE_RS16435
uniprot id: Q21FY4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily.
messages: Catalyzes the decarboxylative condensation of pimeloyl-[acyl-carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide.
messages: Homodimer.

203122:SDE RS17555
gene id: 203122:SDE_RS17555
uniprot id: Q21FB8
names: Similarity
messages: Belongs to the Gfa family.

203122:SDE RS18835
gene id: 203122:SDE_RS18835
uniprot id: Q7PC51
names: Similarity
messages: Belongs to the glycosyl hydrolase 18 family. Chitinase class II subfamily.

203122:SDE RS08660
gene id: 203122:SDE_RS08660
uniprot id: Q21K65
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. TatD-type hydrolase family.

203122:SDE RS15070
gene id: 203122:SDE_RS15070
uniprot id: Q21GP0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

203122:SDE RS01845
gene id: 203122:SDE_RS01845
uniprot id: Q21NW7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm

203122:SDE RS16590
gene id: 203122:SDE_RS16590
uniprot id: Q21FV4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.

203122:SDE RS03370
gene id: 203122:SDE_RS03370
uniprot id: Q21N38
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Cob(I)alamin adenosyltransferase family.
messages: Cytoplasm
messages: Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids.

203122:SDE RS06080
gene id: 203122:SDE_RS06080
uniprot id: Q21LK8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. PdxB subfamily.
messages: Catalyzes the oxidation of erythronate-4-phosphate to 3-hydroxy-2-oxo-4-phosphonooxybutanoate.
messages: Cytoplasm
messages: Homodimer.

203122:SDE RS11460
gene id: 203122:SDE_RS11460
uniprot id: Q21IN2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliG family.
messages: Cell inner membrane
messages: FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
messages: Membrane

203122:SDE RS11330
gene id: 203122:SDE_RS11330
uniprot id: Q21IQ7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CheZ family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P).

203122:SDE RS13850
gene id: 203122:SDE_RS13850
uniprot id: Q21HC4
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

203122:SDE RS07315
gene id: 203122:SDE_RS07315
uniprot id: Q21KX0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

203122:SDE RS01240
gene id: 203122:SDE_RS01240
uniprot id: Q21P82
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Membrane

203122:SDE RS18750
gene id: 203122:SDE_RS18750
uniprot id: Q21EN6
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

203122:SDE RS14125
gene id: 203122:SDE_RS14125
uniprot id: Q21H69
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2).

203122:SDE RS09465
gene id: 203122:SDE_RS09465
uniprot id: Q21JQ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

203122:SDE RS18205
gene id: 203122:SDE_RS18205
uniprot id: Q21EZ3
names: Subcellular Location Annotation
messages: Membrane

203122:SDE RS07235
gene id: 203122:SDE_RS07235
uniprot id: Q21KY6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Catalyzes the dehydration of 6-phospho-D-gluconate to 2-dehydro-3-deoxy-6-phospho-D-gluconate.

203122:SDE RS04520
gene id: 203122:SDE_RS04520
uniprot id: Q21MG0
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArgJ family.
messages: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.
messages: Cytoplasm
messages: Heterotetramer of two alpha and two beta chains.
messages: Some bacteria possess a monofunctional ArgJ, i.e., capable of catalyzing only the fifth step of the arginine biosynthetic pathway.

203122:SDE RS07370
gene id: 203122:SDE_RS07370
uniprot id: Q21KW0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Cell inner membrane
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

203122:SDE RS03530
gene id: 203122:SDE_RS03530
uniprot id: Q21N06
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

203122:SDE RS00075
gene id: 203122:SDE_RS00075
uniprot id: Q21PU3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

203122:SDE RS19005
gene id: 203122:SDE_RS19005
uniprot id: Q21EI6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF nuclease family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

203122:SDE RS00095
gene id: 203122:SDE_RS00095
uniprot id: Q21PV9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TrkH potassium transport family.
messages: Cell inner membrane
messages: Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA.
messages: Membrane

203122:SDE RS01455
gene id: 203122:SDE_RS01455
uniprot id: Q21P40
names: Similarity
messages: Belongs to the band 7/mec-2 family.

203122:SDE RS17700
gene id: 203122:SDE_RS17700
uniprot id: Q21F90
names: Subcellular Location Annotation
messages: Membrane

203122:SDE RS00615
gene id: 203122:SDE_RS00615
uniprot id: Q21PJ6
names: Similarity
messages: Belongs to the outer membrane OOP (TC 1.B.6) superfamily. OmpA family.

203122:SDE RS10970
gene id: 203122:SDE_RS10970
uniprot id: Q21IX9
names: Subcellular Location Annotation
messages: Membrane

203122:SDE RS17815
gene id: 203122:SDE_RS17815
uniprot id: Q21F67
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nicotinamide ribonucleoside (NR) uptake permease (TC 4.B.1) family.
messages: Membrane
messages: Required for nicotinamide riboside transport across the inner membrane.

203122:SDE RS01870
gene id: 203122:SDE_RS01870
uniprot id: Q21NW2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

203122:SDE RS03815
gene id: 203122:SDE_RS03815
uniprot id: Q21MV1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoD/SigA subfamily.
messages: Cytoplasm
messages: Interacts transiently with the RNA polymerase catalytic core.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.

203122:SDE RS17120
gene id: 203122:SDE_RS17120
uniprot id: Q7PC48
names: Similarity
messages: Belongs to the glycosyl hydrolase 20 family.

203122:SDE RS07300
gene id: 203122:SDE_RS07300
uniprot id: Q21KX3
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

203122:SDE RS10595
gene id: 203122:SDE_RS10595
uniprot id: Q21J51
names: Similarity
messages: Belongs to the Nudix hydrolase family.

203122:SDE RS15355
gene id: 203122:SDE_RS15355
uniprot id: Q21GI4
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

203122:SDE RS07005
gene id: 203122:SDE_RS07005
uniprot id: Q21L31
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

203122:SDE RS19215
gene id: 203122:SDE_RS19215
uniprot id: Q21EE6
names: Similarity
messages: Belongs to the UPF0758 family.

203122:SDE RS14160
gene id: 203122:SDE_RS14160
uniprot id: Q21H62
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

203122:SDE RS18970
gene id: 203122:SDE_RS18970
uniprot id: Q21EJ3
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

203122:SDE RS13550
gene id: 203122:SDE_RS13550
uniprot id: Q21HI3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioester dehydratase family. FabZ subfamily.
messages: Cytoplasm
messages: Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.

203122:SDE RS14715
gene id: 203122:SDE_RS14715
uniprot id: Q21GW1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.
messages: Serves to protect the cell against DNA damage by alkyl hydroperoxides. It can use either NADH or NADPH as electron donor for direct reduction of redox dyes or of alkyl hydroperoxides when combined with the AhpC protein.

203122:SDE RS11945
gene id: 203122:SDE_RS11945
uniprot id: Q21ID5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:galactoside symporter (TC 2.A.2) family.
messages: Membrane

203122:SDE RS17155
gene id: 203122:SDE_RS17155
uniprot id: Q21FJ7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

203122:SDE RS14970
gene id: 203122:SDE_RS14970
uniprot id: Q21GR1
names: Subcellular Location Annotation
messages: Membrane

203122:SDE RS02580
gene id: 203122:SDE_RS02580
uniprot id: Q21NJ2
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

203122:SDE RS18825
gene id: 203122:SDE_RS18825
uniprot id: Q21EM1
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

203122:SDE RS13370
gene id: 203122:SDE_RS13370
uniprot id: Q21HL9
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

203122:SDE RS03285
gene id: 203122:SDE_RS03285
uniprot id: Q21N53
names: Similarity
messages: Belongs to the LacAB/RpiB family.

203122:SDE RS17650
gene id: 203122:SDE_RS17650
uniprot id: Q21FA0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

203122:SDE RS17500
gene id: 203122:SDE_RS17500
uniprot id: Q21FC9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

203122:SDE RS07930
gene id: 203122:SDE_RS07930
uniprot id: Q21KK4
names: Similarity
messages: Belongs to the UPF0231 family.

203122:SDE RS04965
gene id: 203122:SDE_RS04965
uniprot id: Q21M77
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Uronate isomerase family.

203122:SDE RS11465
gene id: 203122:SDE_RS11465
uniprot id: Q21IN1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the FliF family.
messages: Membrane
messages: The M ring may be actively involved in energy transduction.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The M ring is integral to the inner membrane of the cell and may be connected to the flagellar rod via the S ring. The S (supramembrane ring) lies just distal to the M ring. The L and P rings lie in the outer membrane and the periplasmic space, respectively.

203122:SDE RS20680
gene id: 203122:SDE_RS20680
uniprot id: Q21DL8
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

203122:SDE RS10555
gene id: 203122:SDE_RS10555
uniprot id: Q21J59
names: Domain
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 dependent methionine synthase family.
messages: Catalyzes the transfer of a methyl group from methyl-cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
messages: Modular enzyme with four functionally distinct domains. The isolated Hcy-binding domain catalyzes methyl transfer from free methylcobalamin to homocysteine. The Hcy-binding domain in association with the pterin-binding domain catalyzes the methylation of cob(I)alamin by methyltetrahydrofolate and the methylation of homocysteine. The B12-binding domain binds the cofactor. The AdoMet activation domain binds S-adenosyl-L-methionine. Under aerobic conditions cob(I)alamin can be converted to inactive cob(II)alamin. Reductive methylation by S-adenosyl-L-methionine and flavodoxin regenerates methylcobalamin.

203122:SDE RS18360
gene id: 203122:SDE_RS18360
uniprot id: Q21EW2
names: Similarity
messages: Belongs to the UbiH/COQ6 family.

203122:SDE RS06060
gene id: 203122:SDE_RS06060
uniprot id: Q21LL2
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

203122:SDE RS08375
gene id: 203122:SDE_RS08375
uniprot id: Q21KB9
names: Function
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. SpeA subfamily.
messages: Catalyzes the biosynthesis of agmatine from arginine.

203122:SDE RS11750
gene id: 203122:SDE_RS11750
uniprot id: Q21IH4
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

203122:SDE RS05680
gene id: 203122:SDE_RS05680
uniprot id: Q21LT3
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

203122:SDE RS06825
gene id: 203122:SDE_RS06825
uniprot id: Q21L65
names: Function
names: Similarity
messages: Belongs to the methylglyoxal synthase family.
messages: Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate.

203122:SDE RS06670
gene id: 203122:SDE_RS06670
uniprot id: Q21L95
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Uronate isomerase family.

203122:SDE RS06190
gene id: 203122:SDE_RS06190
uniprot id: Q21LI9
names: Cofactor
names: Similarity
messages: Belongs to the ApbE family.
messages: Magnesium. Can also use manganese.

203122:SDE RS04785
gene id: 203122:SDE_RS04785
uniprot id: Q21MA7
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

203122:SDE RS06155
gene id: 203122:SDE_RS06155
uniprot id: Q21LJ5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family. QueF type 2 subfamily.
messages: Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
messages: Cytoplasm
messages: Homodimer.

203122:SDE RS02965
gene id: 203122:SDE_RS02965
uniprot id: Q21NB7
names: Similarity
messages: Belongs to the MipA/OmpV family.

203122:SDE RS05700
gene id: 203122:SDE_RS05700
uniprot id: Q21LS9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

203122:SDE RS17660
gene id: 203122:SDE_RS17660
uniprot id: Q21F98
names: Function
names: Similarity
messages: Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control.
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

203122:SDE RS04905
gene id: 203122:SDE_RS04905
uniprot id: Q21M86
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

203122:SDE RS16850
gene id: 203122:SDE_RS16850
uniprot id: Q21FQ1
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

203122:SDE RS09725
gene id: 203122:SDE_RS09725
uniprot id: Q21JL7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. CmoB family.
messages: Catalyzes carboxymethyl transfer from carboxy-S-adenosyl-L-methionine (Cx-SAM) to 5-hydroxyuridine (ho5U) to form 5-carboxymethoxyuridine (cmo5U) at position 34 in tRNAs.
messages: Homotetramer.

203122:SDE RS11320
gene id: 203122:SDE_RS11320
uniprot id: Q21IQ9
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CheB family.
messages: Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.
messages: Cytoplasm
messages: Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
messages: Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity.

203122:SDE RS11070
gene id: 203122:SDE_RS11070
uniprot id: Q21IV9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome b560 family.
messages: Membrane
messages: Membrane-anchoring subunit of succinate dehydrogenase (SDH).
messages: Part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur protein, plus two membrane-anchoring proteins, SdhC and SdhD. The complex can form homotrimers.
messages: The heme is bound between the two transmembrane subunits.

203122:SDE RS08825
gene id: 203122:SDE_RS08825
uniprot id: Q21K32
names: Similarity
messages: Belongs to the ClpA/ClpB family.

203122:SDE RS14225
gene id: 203122:SDE_RS14225
uniprot id: Q21H51
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

203122:SDE RS14725
gene id: 203122:SDE_RS14725
uniprot id: Q21GV9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

203122:SDE RS16480
gene id: 203122:SDE_RS16480
uniprot id: Q21FX6
names: Similarity
messages: Belongs to the UPF0102 family.

203122:SDE RS08790
gene id: 203122:SDE_RS08790
uniprot id: Q21K39
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SNF2/RAD54 helicase family. RapA subfamily.
messages: Interacts with the RNAP. Has a higher affinity for the core RNAP than for the holoenzyme. Its ATPase activity is stimulated by binding to RNAP.
messages: Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair.

203122:SDE RS10980
gene id: 203122:SDE_RS10980
uniprot id: Q21IX7
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmB subfamily.
messages: Methylates ribosomal protein uL3 on a specific glutamine residue.
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

203122:SDE RS15245
gene id: 203122:SDE_RS15245
uniprot id: Q21GK7
names: Similarity
messages: Belongs to the D-alanine--D-alanine ligase family.

203122:SDE RS09435
gene id: 203122:SDE_RS09435
uniprot id: Q21JR4
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

203122:SDE RS11500
gene id: 203122:SDE_RS11500
uniprot id: Q21IM3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliS family.
messages: cytosol

203122:SDE RS12830
gene id: 203122:SDE_RS12830
uniprot id: Q21HW7
names: Subcellular Location Annotation
messages: Membrane

203122:SDE RS17685
gene id: 203122:SDE_RS17685
uniprot id: Q21F93
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

203122:SDE RS13955
gene id: 203122:SDE_RS13955
uniprot id: Q21HA3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

203122:SDE RS05330
gene id: 203122:SDE_RS05330
uniprot id: Q21M04
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

203122:SDE RS17050
gene id: 203122:SDE_RS17050
uniprot id: Q21FL6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

203122:SDE RS18495
gene id: 203122:SDE_RS18495
uniprot id: Q21ET7
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

203122:SDE RS10640
gene id: 203122:SDE_RS10640
uniprot id: Q21J42
names: Similarity
messages: Belongs to the bacterial solute-binding protein 5 family.

203122:SDE RS04720
gene id: 203122:SDE_RS04720
uniprot id: Q21MC0
names: Similarity
messages: Belongs to the peptidase S49 family.

203122:SDE RS05130
gene id: 203122:SDE_RS05130
uniprot id: Q21M45
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

203122:SDE RS04265
gene id: 203122:SDE_RS04265
uniprot id: Q21ML1
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

203122:SDE RS09390
gene id: 203122:SDE_RS09390
uniprot id: Q21JS3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

203122:SDE RS08530
gene id: 203122:SDE_RS08530
uniprot id: Q21K90
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsX family.
messages: Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
messages: Cytoplasm
messages: Homodimer. Probably interacts with PlsY.

203122:SDE RS11170
gene id: 203122:SDE_RS11170
uniprot id: Q21IT9
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

203122:SDE RS10720
gene id: 203122:SDE_RS10720
uniprot id: Q21J26
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Membrane

203122:SDE RS08830
gene id: 203122:SDE_RS08830
uniprot id: Q21K31
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

203122:SDE RS00670
gene id: 203122:SDE_RS00670
uniprot id: Q21PI6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferrochelatase family.
messages: Catalyzes the ferrous insertion into protoporphyrin IX.
messages: Cytoplasm

203122:SDE RS14345
gene id: 203122:SDE_RS14345
uniprot id: Q21H28
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

203122:SDE RS19460
gene id: 203122:SDE_RS19460
uniprot id: Q21E99
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: In the C-terminal section; belongs to the NRP synthetase family.

203122:SDE RS21370
gene id: 203122:SDE_RS21370
uniprot id: Q21HK7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP H family.
messages: Cell inner membrane
messages: Membrane

203122:SDE RS13665
gene id: 203122:SDE_RS13665
uniprot id: Q21HG0
names: Similarity
messages: Belongs to the MoaD family.

203122:SDE RS18670
gene id: 203122:SDE_RS18670
uniprot id: Q21EQ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP L family.
messages: Cell inner membrane
messages: Inner membrane component of the type II secretion system required for the energy-dependent secretion of extracellular factors such as proteases and toxins from the periplasm.
messages: Membrane

203122:SDE RS08505
gene id: 203122:SDE_RS08505
uniprot id: Q21K95
names: Similarity
messages: Belongs to the peptidase S49 family.

203122:SDE RS12990
gene id: 203122:SDE_RS12990
uniprot id: Q21HT5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

203122:SDE RS02190
gene id: 203122:SDE_RS02190
uniprot id: Q21NP8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.

203122:SDE RS20550
gene id: 203122:SDE_RS20550
uniprot id: Q21DP2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0718 family.
messages: Cell membrane
messages: Membrane

203122:SDE RS07530
gene id: 203122:SDE_RS07530
uniprot id: Q21KS9
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

203122:SDE RS12865
gene id: 203122:SDE_RS12865
uniprot id: Q21HW0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.
messages: Binds 2 iron ions per subunit.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

203122:SDE RS18925
gene id: 203122:SDE_RS18925
uniprot id: Q21EK2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inositol monophosphatase superfamily. CysQ family.
messages: Cell inner membrane
messages: Converts adenosine-3',5'-bisphosphate (PAP) to AMP.

203122:SDE RS14220
gene id: 203122:SDE_RS14220
uniprot id: Q21H52
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

203122:SDE RS07825
gene id: 203122:SDE_RS07825
uniprot id: Q21KM2
names: Cofactor
names: Similarity
messages: Belongs to the nitroreductase family.
messages: Binds 1 FMN per subunit.

203122:SDE RS10650
gene id: 203122:SDE_RS10650
uniprot id: Q21J40
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

203122:SDE RS04055
gene id: 203122:SDE_RS04055
uniprot id: Q21MQ3
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. NasA/NapA/NarB subfamily.

203122:SDE RS17010
gene id: 203122:SDE_RS17010
uniprot id: Q21FM3
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

203122:SDE RS11510
gene id: 203122:SDE_RS11510
uniprot id: Q21IM1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum
messages: Belongs to the FliD family.
messages: Homopentamer.
messages: Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.
messages: Secreted

203122:SDE RS01370
gene id: 203122:SDE_RS01370
uniprot id: Q21P56
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MgtC/SapB family.
messages: Cell inner membrane
messages: Membrane

203122:SDE RS11580
gene id: 203122:SDE_RS11580
uniprot id: Q21IK7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

203122:SDE RS21150
gene id: 203122:SDE_RS21150
uniprot id: Q21ML8
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

203122:SDE RS06050
gene id: 203122:SDE_RS06050
uniprot id: Q21LL4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily.
messages: Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA.
messages: Cytoplasm
messages: Monomer.

203122:SDE RS16390
gene id: 203122:SDE_RS16390
uniprot id: Q21FZ3
names: Subcellular Location Annotation
messages: Nucleus

203122:SDE RS20445
gene id: 203122:SDE_RS20445
uniprot id: Q21DR3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC41A transporter family.
messages: Membrane

203122:SDE RS10840
gene id: 203122:SDE_RS10840
uniprot id: Q21J04
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

203122:SDE RS04275
gene id: 203122:SDE_RS04275
uniprot id: Q21MK9
names: Function
names: Similarity
messages: Belongs to the Dus family. DusB subfamily.
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

203122:SDE RS08685
gene id: 203122:SDE_RS08685
uniprot id: Q21K60
names: Function
names: Similarity
messages: Belongs to the LDH/MDH superfamily. MDH type 2 family.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.

203122:SDE RS11950
gene id: 203122:SDE_RS11950
uniprot id: Q21ID4
names: Similarity
messages: Belongs to the glycosyl hydrolase 5 (cellulase A) family.

203122:SDE RS04770
gene id: 203122:SDE_RS04770
uniprot id: Q21MB0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:galactoside symporter (TC 2.A.2) family.
messages: Membrane

203122:SDE RS18325
gene id: 203122:SDE_RS18325
uniprot id: Q21EW9
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

203122:SDE RS17665
gene id: 203122:SDE_RS17665
uniprot id: Q21F97
names: Function
names: Similarity
messages: Belongs to the HPPK family.
messages: Catalyzes the transfer of pyrophosphate from adenosine triphosphate (ATP) to 6-hydroxymethyl-7,8-dihydropterin, an enzymatic step in folate biosynthesis pathway.

203122:SDE RS06795
gene id: 203122:SDE_RS06795
uniprot id: Q21L70
names: Similarity
messages: Belongs to the UPF0434 family.

203122:SDE RS10935
gene id: 203122:SDE_RS10935
uniprot id: Q21IY6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.

203122:SDE RS08910
gene id: 203122:SDE_RS08910
uniprot id: Q21K16
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polysaccharide lyase 3 family.
messages: Catalyzes the depolymerization of both polygalacturonate and pectins of methyl esterification degree from 22 to 89%, with an endo mode of action. In contrast to the majority of pectate lyases, displays high activity on highly methylated pectins.
messages: Secreted

203122:SDE RS06525
gene id: 203122:SDE_RS06525
uniprot id: Q21LC4
names: Activity Regulation
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.

203122:SDE RS07140
gene id: 203122:SDE_RS07140
uniprot id: Q21L05
names: Similarity
messages: Belongs to the GSP E family.

203122:SDE RS13980
gene id: 203122:SDE_RS13980
uniprot id: Q21H98
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm

203122:SDE RS05570
gene id: 203122:SDE_RS05570
uniprot id: Q21LV5
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanD family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
messages: Cytoplasm
messages: Heterooctamer of four alpha and four beta subunits.
messages: Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus.

203122:SDE RS07740
gene id: 203122:SDE_RS07740
uniprot id: Q21KN9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: In the N-terminal section; belongs to the FGAMS family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.

203122:SDE RS21615
gene id: 203122:SDE_RS21615
uniprot id: Q21EL2
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

203122:SDE RS20685
gene id: 203122:SDE_RS20685
uniprot id: Q21DL7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

203122:SDE RS11210
gene id: 203122:SDE_RS11210
uniprot id: Q21IT1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LapB family.
messages: Cell inner membrane
messages: Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane.

203122:SDE RS15085
gene id: 203122:SDE_RS15085
uniprot id: Q21GN7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

203122:SDE RS06175
gene id: 203122:SDE_RS06175
uniprot id: Q21LJ2
names: Similarity
messages: Belongs to the glycosyl hydrolase 16 family.

203122:SDE RS19480
gene id: 203122:SDE_RS19480
uniprot id: Q21E96
names: Similarity
messages: Belongs to the thioesterase family.

203122:SDE RS06450
gene id: 203122:SDE_RS06450
uniprot id: Q21LD9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Cell inner membrane
messages: Membrane

203122:SDE RS11015
gene id: 203122:SDE_RS11015
uniprot id: Q21IX0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the heat shock protein 90 family.
messages: Cytoplasm
messages: Homodimer.
messages: Molecular chaperone. Has ATPase activity.

203122:SDE RS14050
gene id: 203122:SDE_RS14050
uniprot id: Q21H84
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
messages: Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).
messages: Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
messages: Cytoplasm

203122:SDE RS09875
gene id: 203122:SDE_RS09875
uniprot id: Q21JI9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ZipA family.
messages: Cell inner membrane
messages: Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins.
messages: Interacts with FtsZ via their C-terminal domains.

203122:SDE RS05690
gene id: 203122:SDE_RS05690
uniprot id: Q21LT1
names: Function
names: Similarity
messages: Belongs to the anhydro-N-acetylmuramic acid kinase family.
messages: Catalyzes the specific phosphorylation of 1,6-anhydro-N-acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling.

203122:SDE RS12535
gene id: 203122:SDE_RS12535
uniprot id: Q21I25
names: Cofactor
messages: Binds 2 Mg(2+) ions per monomer.

203122:SDE RS08665
gene id: 203122:SDE_RS08665
uniprot id: Q21K64
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

203122:SDE RS11370
gene id: 203122:SDE_RS11370
uniprot id: Q21IQ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type III secretion exporter family.
messages: Cell membrane
messages: Membrane
messages: Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

203122:SDE RS15520
gene id: 203122:SDE_RS15520
uniprot id: Q21GF4
names: Subcellular Location Annotation
messages: Membrane

203122:SDE RS09205
gene id: 203122:SDE_RS09205
uniprot id: Q21JW0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

203122:SDE RS05685
gene id: 203122:SDE_RS05685
uniprot id: Q21LT2
names: Similarity
messages: Belongs to the SOS response-associated peptidase family.

203122:SDE RS10190
gene id: 203122:SDE_RS10190
uniprot id: Q21JD2
names: Subcellular Location Annotation
messages: Membrane

203122:SDE RS17015
gene id: 203122:SDE_RS17015
uniprot id: Q21FM2
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

203122:SDE RS04680
gene id: 203122:SDE_RS04680
uniprot id: Q21MC8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

203122:SDE RS04580
gene id: 203122:SDE_RS04580
uniprot id: Q21ME8
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

203122:SDE RS00150
gene id: 203122:SDE_RS00150
uniprot id: Q21PT7
names: Subcellular Location Annotation
messages: Membrane

203122:SDE RS02185
gene id: 203122:SDE_RS02185
uniprot id: Q21NP9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.
messages: Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.
messages: Cytoplasm
messages: Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).
messages: The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.
messages: The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1.

203122:SDE RS17455
gene id: 203122:SDE_RS17455
uniprot id: Q21FD8
names: Similarity
messages: Belongs to the UPF0250 family.

203122:SDE RS17215
gene id: 203122:SDE_RS17215
uniprot id: Q21FI6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MntP (TC 9.B.29) family.
messages: Cell inner membrane
messages: Probably functions as a manganese efflux pump.

203122:SDE RS01265
gene id: 203122:SDE_RS01265
uniprot id: Q21P77
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

203122:SDE RS04515
gene id: 203122:SDE_RS04515
uniprot id: Q21MG1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell inner membrane
messages: Cytoplasm
messages: May bind 1 zinc ion per subunit.
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

203122:SDE RS17490
gene id: 203122:SDE_RS17490
uniprot id: Q21FD1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein uL14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein uL14 (rplN).

203122:SDE RS17715
gene id: 203122:SDE_RS17715
uniprot id: Q21F87
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ribose 5-phosphate isomerase family.
messages: Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
messages: Homodimer.

203122:SDE RS16640
gene id: 203122:SDE_RS16640
uniprot id: Q21FU4
names: Function
names: Similarity
messages: Belongs to the ABC transporter superfamily. Outer membrane lipopolysaccharide export (TC 1.B.42) family.
messages: Part of the ABC transporter complex LptBFG involved in the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane. Probably responsible for energy coupling to the transport system.

203122:SDE RS18160
gene id: 203122:SDE_RS18160
uniprot id: Q21F02
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Cell inner membrane
messages: Homoheptamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mechanosensitive channel that participates in the regulation of osmotic pressure changes within the cell, opening in response to stretch forces in the membrane lipid bilayer, without the need for other proteins. Contributes to normal resistance to hypoosmotic shock. Forms an ion channel of 1.0 nanosiemens conductance with a slight preference for anions.

203122:SDE RS12560
gene id: 203122:SDE_RS12560
uniprot id: Q21I20
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell inner membrane
messages: Membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

203122:SDE RS16625
gene id: 203122:SDE_RS16625
uniprot id: Q21FU7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the KdsC family.
messages: Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate.
messages: Homotetramer.

203122:SDE RS01320
gene id: 203122:SDE_RS01320
uniprot id: Q21P66
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

203122:SDE RS08545
gene id: 203122:SDE_RS08545
uniprot id: Q21K87
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

203122:SDE RS15890
gene id: 203122:SDE_RS15890
uniprot id: Q21G88
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DEAD box helicase family. DeaD/CsdA subfamily.
messages: Cytoplasm
messages: DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation.

203122:SDE RS13435
gene id: 203122:SDE_RS13435
uniprot id: Q21HK6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

203122:SDE RS10430
gene id: 203122:SDE_RS10430
uniprot id: Q21J84
names: Similarity
messages: Belongs to the Dps family.

203122:SDE RS12760
gene id: 203122:SDE_RS12760
uniprot id: Q21HY1
names: Similarity
messages: Belongs to the glutaredoxin family. Monothiol subfamily.

203122:SDE RS08145
gene id: 203122:SDE_RS08145
uniprot id: Q21KG2
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

203122:SDE RS04395
gene id: 203122:SDE_RS04395
uniprot id: Q21MI5
names: Subcellular Location Annotation
messages: Membrane

203122:SDE RS12630
gene id: 203122:SDE_RS12630
uniprot id: Q21I06
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the glyoxalase I family.
messages: Binds 1 nickel ion per subunit.
messages: Binds 1 zinc ion per subunit. In the homodimer, two zinc ions are bound between subunits.
messages: Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione.

203122:SDE RS06575
gene id: 203122:SDE_RS06575
uniprot id: Q21LB4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoS subfamily.
messages: Cytoplasm
messages: Interacts with the RNA polymerase core enzyme.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the master transcriptional regulator of the stationary phase and the general stress response.

203122:SDE RS11665
gene id: 203122:SDE_RS11665
uniprot id: Q21IJ1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm
messages: Homodimer.

203122:SDE RS13490
gene id: 203122:SDE_RS13490
uniprot id: Q21HJ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

203122:SDE RS15255
gene id: 203122:SDE_RS15255
uniprot id: Q21GK5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

203122:SDE RS11360
gene id: 203122:SDE_RS11360
uniprot id: Q21IQ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.
messages: Cell membrane
messages: Membrane
messages: Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

203122:SDE RS05295
gene id: 203122:SDE_RS05295
uniprot id: Q21M11
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm

203122:SDE RS12680
gene id: 203122:SDE_RS12680
uniprot id: Q21HZ6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.

203122:SDE RS04375
gene id: 203122:SDE_RS04375
uniprot id: Q21MI9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).

203122:SDE RS09660
gene id: 203122:SDE_RS09660
uniprot id: Q21JN0
names: Similarity
messages: Belongs to the AHA1 family.

203122:SDE RS17180
gene id: 203122:SDE_RS17180
uniprot id: Q21FJ2
names: Subcellular Location Annotation
messages: Membrane

203122:SDE RS05590
gene id: 203122:SDE_RS05590
uniprot id: Q21LV1
names: Similarity
messages: Belongs to the universal stress protein A family.

203122:SDE RS17295
gene id: 203122:SDE_RS17295
uniprot id: Q21FH0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CN hydrolase family. Apolipoprotein N-acyltransferase subfamily.
messages: Catalyzes the phospholipid dependent N-acylation of the N-terminal cysteine of apolipoprotein, the last step in lipoprotein maturation.
messages: Cell inner membrane
messages: Membrane

203122:SDE RS05220
gene id: 203122:SDE_RS05220
uniprot id: Q21M25
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Cytoplasm
messages: Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.
messages: Monomer.

203122:SDE RS18290
gene id: 203122:SDE_RS18290
uniprot id: Q21EX6
names: Similarity
messages: Belongs to the autoinducer synthase family.

203122:SDE RS12470
gene id: 203122:SDE_RS12470
uniprot id: Q21I38
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the helicase family. DinG subfamily. Type 1 sub-subfamily.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA-dependent ATPase and 5'-3' DNA helicase.

203122:SDE RS18025
gene id: 203122:SDE_RS18025
uniprot id: Q21F28
names: Subcellular Location Annotation
messages: Membrane

203122:SDE RS18675
gene id: 203122:SDE_RS18675
uniprot id: Q21EQ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP K family.
messages: Cell inner membrane
messages: Membrane

203122:SDE RS03265
gene id: 203122:SDE_RS03265
uniprot id: Q21N57
names: Similarity
messages: Belongs to the polysaccharide lyase 3 family.

203122:SDE RS08425
gene id: 203122:SDE_RS08425
uniprot id: Q21KB0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

203122:SDE RS08160
gene id: 203122:SDE_RS08160
uniprot id: Q21KF9
names: Similarity
messages: Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family.

203122:SDE RS00195
gene id: 203122:SDE_RS00195
uniprot id: Q21PS8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Cell membrane
messages: Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.
messages: Membrane

203122:SDE RS01185
gene id: 203122:SDE_RS01185
uniprot id: Q21P93
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UreE family.
messages: Cytoplasm
messages: Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly.

203122:SDE RS06435
gene id: 203122:SDE_RS06435
uniprot id: Q21LE2
names: Subcellular Location Annotation
messages: Membrane

203122:SDE RS11770
gene id: 203122:SDE_RS11770
uniprot id: Q21IH0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RseB family.
messages: Periplasm

203122:SDE RS20310
gene id: 203122:SDE_RS20310
uniprot id: Q21DU0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

203122:SDE RS06035
gene id: 203122:SDE_RS06035
uniprot id: Q21LL7
names: Subcellular Location Annotation
messages: Cytoplasm

203122:SDE RS13120
gene id: 203122:SDE_RS13120
uniprot id: Q21HR2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

203122:SDE RS19015
gene id: 203122:SDE_RS19015
uniprot id: Q21EI4
names: Similarity
messages: Belongs to the GSP E family.

203122:SDE RS09260
gene id: 203122:SDE_RS09260
uniprot id: Q21JU9
names: Subcellular Location Annotation
messages: Membrane

203122:SDE RS21325
gene id: 203122:SDE_RS21325
uniprot id: Q21IB1
names: Similarity
messages: Belongs to the polysaccharide lyase 3 family.

203122:SDE RS06550
gene id: 203122:SDE_RS06550
uniprot id: Q21LB9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IspF family.
messages: Binds 1 divalent metal cation per subunit.
messages: Homotrimer.
messages: Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).

203122:SDE RS08770
gene id: 203122:SDE_RS08770
uniprot id: Q21K43
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HflD family.
messages: Cell inner membrane
messages: Cytoplasm

203122:SDE RS13930
gene id: 203122:SDE_RS13930
uniprot id: Q21HA8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

203122:SDE RS11205
gene id: 203122:SDE_RS11205
uniprot id: Q21IT2
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS1 family.
messages: Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence.

203122:SDE RS14140
gene id: 203122:SDE_RS14140
uniprot id: Q21H66
names: Similarity
messages: Belongs to the MipA/OmpV family.

203122:SDE RS01905
gene id: 203122:SDE_RS01905
uniprot id: Q21NV5
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetyltransferase family. ArgA subfamily.
messages: Cytoplasm
messages: In bacteria which possess the bifunctional enzyme ornithine acetyltransferase/N-acetylglutamate synthase (ArgJ), ArgA fulfills an anaplerotic role.

203122:SDE RS21555
gene id: 203122:SDE_RS21555
uniprot id: Q21FN5
names: Similarity
messages: Belongs to the glycosyl hydrolase 5 (cellulase A) family.

203122:SDE RS06785
gene id: 203122:SDE_RS06785
uniprot id: Q21L72
names: Similarity
messages: Belongs to the AB hydrolase superfamily. AB hydrolase 4 family.

203122:SDE RS04930
gene id: 203122:SDE_RS04930
uniprot id: Q21M84
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

203122:SDE RS02770
gene id: 203122:SDE_RS02770
uniprot id: Q21NF5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

203122:SDE RS00230
gene id: 203122:SDE_RS00230
uniprot id: Q21PS1
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
messages: Carbon 2 of the heme B porphyrin ring is defined according to the Fischer nomenclature.
messages: Cell inner membrane
messages: Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.

203122:SDE RS12815
gene id: 203122:SDE_RS12815
uniprot id: Q21HX0
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

203122:SDE RS11740
gene id: 203122:SDE_RS11740
uniprot id: Q21IH6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

203122:SDE RS07440
gene id: 203122:SDE_RS07440
uniprot id: Q21KU7
names: Similarity
messages: Belongs to the SufE family.

203122:SDE RS08265
gene id: 203122:SDE_RS08265
uniprot id: Q21KE0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr). Also edits incorrectly charged L-seryl-tRNA(Thr).
messages: Cytoplasm
messages: Homodimer.

203122:SDE RS05160
gene id: 203122:SDE_RS05160
uniprot id: Q21M38
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell inner membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

203122:SDE RS13990
gene id: 203122:SDE_RS13990
uniprot id: Q21H96
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueG family.
messages: Binds 2 [4Fe-4S] clusters per monomer.
messages: Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

203122:SDE RS04700
gene id: 203122:SDE_RS04700
uniprot id: Q21MC4
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.

203122:SDE RS00025
gene id: 203122:SDE_RS00025
uniprot id: Q21PV3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

203122:SDE RS05100
gene id: 203122:SDE_RS05100
uniprot id: Q21M50
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

203122:SDE RS10655
gene id: 203122:SDE_RS10655
uniprot id: Q21J39
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

203122:SDE RS14990
gene id: 203122:SDE_RS14990
uniprot id: Q21GQ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lactate permease family.
messages: Cell inner membrane
messages: Membrane
messages: Uptake of L-lactate across the membrane. Can also transport D-lactate and glycolate.

203122:SDE RS00305
gene id: 203122:SDE_RS00305
uniprot id: Q21PQ6
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 zinc ion per subunit.

203122:SDE RS17370
gene id: 203122:SDE_RS17370
uniprot id: Q21FF5
names: Similarity
messages: Belongs to the YciI family.

203122:SDE RS01440
gene id: 203122:SDE_RS01440
uniprot id: Q21P42
names: Cofactor
names: Similarity
messages: Belongs to the RtcB family.
messages: Binds 2 manganese ions per subunit.

203122:SDE RS16015
gene id: 203122:SDE_RS16015
uniprot id: Q21G64
names: Similarity
messages: Belongs to the PhzF family.

203122:SDE RS05755
gene id: 203122:SDE_RS05755
uniprot id: Q21LR9
names: Cofactor
names: Similarity
messages: Belongs to the galactose-1-phosphate uridylyltransferase type 1 family.
messages: Binds 1 zinc ion per subunit.

203122:SDE RS02715
gene id: 203122:SDE_RS02715
uniprot id: Q21NG6
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Member of the two-component regulatory system NtrB/NtrC, which controls expression of the nitrogen-regulated (ntr) genes in response to nitrogen limitation. Phosphorylated NtrC binds directly to DNA and stimulates the formation of open promoter-sigma54-RNA polymerase complexes.

203122:SDE RS13480
gene id: 203122:SDE_RS13480
uniprot id: Q21HJ7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 3 lipoyl cofactors covalently.
messages: Forms a 24-polypeptide structural core with octahedral symmetry.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).

203122:SDE RS10150
gene id: 203122:SDE_RS10150
uniprot id: Q21JE0
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

203122:SDE RS16500
gene id: 203122:SDE_RS16500
uniprot id: Q21FX2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LemA family.
messages: Membrane

203122:SDE RS17485
gene id: 203122:SDE_RS17485
uniprot id: Q21FD2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

203122:SDE RS08280
gene id: 203122:SDE_RS08280
uniprot id: Q21KD7
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

203122:SDE RS12460
gene id: 203122:SDE_RS12460
uniprot id: Q21I40
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

203122:SDE RS06955
gene id: 203122:SDE_RS06955
uniprot id: Q21L41
names: Subcellular Location Annotation
messages: Cytoplasm

203122:SDE RS04165
gene id: 203122:SDE_RS04165
uniprot id: Q21MN1
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

203122:SDE RS04075
gene id: 203122:SDE_RS04075
uniprot id: Q21MP9
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

203122:SDE RS02815
gene id: 203122:SDE_RS02815
uniprot id: Q21NE6
names: Function
messages: Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors. CheA is autophosphorylated; it can transfer its phosphate group to either CheB or CheY.

203122:SDE RS04305
gene id: 203122:SDE_RS04305
uniprot id: Q21MK3
names: Subcellular Location Annotation
messages: Membrane

203122:SDE RS15125
gene id: 203122:SDE_RS15125
uniprot id: Q21GM9
names: Similarity
messages: Belongs to the YkuD family.

203122:SDE RS10280
gene id: 203122:SDE_RS10280
uniprot id: Q21JB4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

203122:SDE RS09945
gene id: 203122:SDE_RS09945
uniprot id: Q21JH6
names: Cofactor
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.
messages: Binds 1 [4Fe-4S] cluster per subunit.

203122:SDE RS07105
gene id: 203122:SDE_RS07105
uniprot id: Q21L11
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.

203122:SDE RS14005
gene id: 203122:SDE_RS14005
uniprot id: Q21H93
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-to-5' exoribonuclease specific for small oligoribonucleotides.
messages: Belongs to the oligoribonuclease family.
messages: Cytoplasm

203122:SDE RS02550
gene id: 203122:SDE_RS02550
uniprot id: Q21NJ8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

203122:SDE RS09265
gene id: 203122:SDE_RS09265
uniprot id: Q21JU8
names: Subcellular Location Annotation
messages: Membrane

203122:SDE RS13585
gene id: 203122:SDE_RS13585
uniprot id: Q21HH6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with (2E,6E)-farnesyl diphosphate (E,E-FPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E,38E)-undecaprenyl diphosphate (di-trans,octa-cis-UPP). UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

203122:SDE RS18685
gene id: 203122:SDE_RS18685
uniprot id: Q21EP9
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GSP I family.
messages: Cell inner membrane
messages: Cleaved by prepilin peptidase.
messages: Component of the type II secretion system required for the energy-dependent secretion of extracellular factors such as proteases and toxins from the periplasm.
messages: Membrane
messages: Type II secretion is composed of four main components: the outer membrane complex, the inner membrane complex, the cytoplasmic secretion ATPase and the periplasm-spanning pseudopilus.

203122:SDE RS06015
gene id: 203122:SDE_RS06015
uniprot id: Q21LM1
names: Similarity
messages: Belongs to the ice-binding protein family.

203122:SDE RS06975
gene id: 203122:SDE_RS06975
uniprot id: Q21L37
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

203122:SDE RS05065
gene id: 203122:SDE_RS05065
uniprot id: Q21M57
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: Methylated by PrmB.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

203122:SDE RS13460
gene id: 203122:SDE_RS13460
uniprot id: Q21HK1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurJ/MviN family.
messages: Cell inner membrane
messages: Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.
messages: Membrane

203122:SDE RS07575
gene id: 203122:SDE_RS07575
uniprot id: Q21KS0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YejK family.
messages: nucleoid

203122:SDE RS12575
gene id: 203122:SDE_RS12575
uniprot id: Q21I17
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Cell inner membrane
messages: Homoheptamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mechanosensitive channel that participates in the regulation of osmotic pressure changes within the cell, opening in response to stretch forces in the membrane lipid bilayer, without the need for other proteins. Contributes to normal resistance to hypoosmotic shock. Forms an ion channel of 1.0 nanosiemens conductance with a slight preference for anions.
messages: Membrane

203122:SDE RS04390
gene id: 203122:SDE_RS04390
uniprot id: Q21MI6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HemJ family.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.
messages: Catalyzes the oxidation of protoporphyrinogen IX to protoporphyrin IX.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

203122:SDE RS13225
gene id: 203122:SDE_RS13225
uniprot id: Q21HP3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.
messages: Binds 1 S-adenosyl-L-methionine per subunit.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

203122:SDE RS04135
gene id: 203122:SDE_RS04135
uniprot id: Q21MN7
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

203122:SDE RS05350
gene id: 203122:SDE_RS05350
uniprot id: Q21M00
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. FHS transporter (TC 2.A.1.7) family.
messages: Cell inner membrane
messages: Intake of glucose and galactose.
messages: Membrane

203122:SDE RS18195
gene id: 203122:SDE_RS18195
uniprot id: Q21EZ5
names: Similarity
messages: Belongs to the PspA/IM30 family.

203122:SDE RS19485
gene id: 203122:SDE_RS19485
uniprot id: Q21E95
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

203122:SDE RS20865
gene id: 203122:SDE_RS20865
uniprot id: Q21DI2
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MsrP family.
messages: Binds 1 Mo-molybdopterin (Mo-MPT) cofactor per subunit.
messages: Heterodimer of a catalytic subunit (MsrP) and a heme-binding subunit (MsrQ).
messages: Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide.
messages: Periplasm
messages: Predicted to be exported by the Tat system. The position of the signal peptide cleavage has not been experimentally proven.

203122:SDE RS04885
gene id: 203122:SDE_RS04885
uniprot id: Q21M92
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

203122:SDE RS08625
gene id: 203122:SDE_RS08625
uniprot id: Q21K72
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

203122:SDE RS11530
gene id: 203122:SDE_RS11530
uniprot id: Q21IL7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

203122:SDE RS20950
gene id: 203122:SDE_RS20950
uniprot id: Q21DG5
names: Function
names: Similarity
messages: Belongs to the ParB family.
messages: Involved in chromosome partition. Localize to both poles of the predivisional cell following completion of DNA replication. Binds to the DNA origin of replication.

203122:SDE RS12015
gene id: 203122:SDE_RS12015
uniprot id: Q21IC1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Cytoplasm
messages: Homodimer.

203122:SDE RS16495
gene id: 203122:SDE_RS16495
uniprot id: Q21FX3
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

203122:SDE RS04920
gene id: 203122:SDE_RS04920
uniprot id: Q21M86
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

203122:SDE RS02195
gene id: 203122:SDE_RS02195
uniprot id: Q21NP7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

203122:SDE RS16645
gene id: 203122:SDE_RS16645
uniprot id: Q21FU3
names: Function
names: Similarity
messages: Belongs to the sigma-54 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

203122:SDE RS06675
gene id: 203122:SDE_RS06675
uniprot id: Q21L94
names: Function
names: Similarity
messages: Belongs to the mannonate dehydratase family.
messages: Catalyzes the dehydration of D-mannonate.

203122:SDE RS09240
gene id: 203122:SDE_RS09240
uniprot id: Q21JV3
names: Similarity
messages: Belongs to the arylamine N-acetyltransferase family.

203122:SDE RS16755
gene id: 203122:SDE_RS16755
uniprot id: Q21FS1
names: Similarity
messages: Belongs to the prokaryotic/mitochondrial release factor family.