2027290:CYG50 RS11400
gene id: 2027290:CYG50_RS11400
uniprot id: A0A345LSC4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 3 family.
messages: Cell membrane
messages: NDH-1 is composed of 13 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

2027290:CYG50 RS04730
gene id: 2027290:CYG50_RS04730
uniprot id: A0A345LVS3
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS1 family.
messages: Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence.

2027290:CYG50 RS20285
gene id: 2027290:CYG50_RS20285
uniprot id: A0A345LYT2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliQ/MopD/SpaQ family.
messages: Cell membrane
messages: Membrane

2027290:CYG50 RS19760
gene id: 2027290:CYG50_RS19760
uniprot id: A0A345LZ21
names: Subcellular Location Annotation
messages: Membrane

2027290:CYG50 RS01755
gene id: 2027290:CYG50_RS01755
uniprot id: A0A345LXC8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.
messages: Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.
messages: Cytoplasm
messages: Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).
messages: The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.
messages: The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1.

2027290:CYG50 RS06395
gene id: 2027290:CYG50_RS06395
uniprot id: A0A345LUX1
names: Similarity
messages: Belongs to the phage portal family. PBSX subfamily.

2027290:CYG50 RS04045
gene id: 2027290:CYG50_RS04045
uniprot id: A0A345LW57
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gluconeogenesis factor family.
messages: Cytoplasm
messages: Required for morphogenesis under gluconeogenic growth conditions.

2027290:CYG50 RS18155
gene id: 2027290:CYG50_RS18155
uniprot id: A0A345LZV7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

2027290:CYG50 RS22325
gene id: 2027290:CYG50_RS22325
uniprot id: A0A345LXQ3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell membrane
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

2027290:CYG50 RS18100
gene id: 2027290:CYG50_RS18100
uniprot id: A0A345LZW8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

2027290:CYG50 RS17440
gene id: 2027290:CYG50_RS17440
uniprot id: A0A345M077
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ArgR family.
messages: Cytoplasm
messages: Regulates arginine biosynthesis genes.

2027290:CYG50 RS15960
gene id: 2027290:CYG50_RS15960
uniprot id: A0A345M103
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

2027290:CYG50 RS16080
gene id: 2027290:CYG50_RS16080
uniprot id: A0A345M0X9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FrdC family.
messages: Cell membrane
messages: Part of an enzyme complex containing four subunits: a flavoprotein (FrdA), an iron-sulfur protein (FrdB), and two hydrophobic anchor proteins (FrdC and FrdD).
messages: Two distinct, membrane-bound, FAD-containing enzymes are responsible for the catalysis of fumarate and succinate interconversion; fumarate reductase is used in anaerobic growth, and succinate dehydrogenase is used in aerobic growth. Anchors the catalytic components of the fumarate reductase complex to the cell inner membrane, binds quinones.

2027290:CYG50 RS12045
gene id: 2027290:CYG50_RS12045
uniprot id: A0A345LS11
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.
messages: Cytoplasm
messages: Homodimer. Forms a heterotetramer with IscU, interacts with other sulfur acceptors.
messages: Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins.

2027290:CYG50 RS18150
gene id: 2027290:CYG50_RS18150
uniprot id: A0A345LZV8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

2027290:CYG50 RS04085
gene id: 2027290:CYG50_RS04085
uniprot id: A0A345LW49
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

2027290:CYG50 RS17135
gene id: 2027290:CYG50_RS17135
uniprot id: A0A8I2AMT5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RraB family.
messages: Cytoplasm
messages: Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome.
messages: Interacts with the C-terminal region of Rne.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

2027290:CYG50 RS00635
gene id: 2027290:CYG50_RS00635
uniprot id: A0A345LR93
names: Function
messages: TetR is the repressor of the tetracycline resistance element; its N-terminal region forms a helix-turn-helix structure and binds DNA. Binding of tetracycline to TetR reduces the repressor affinity for the tetracycline resistance gene (tetA) promoter operator sites.

2027290:CYG50 RS17330
gene id: 2027290:CYG50_RS17330
uniprot id: A0A345M096
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

2027290:CYG50 RS19835
gene id: 2027290:CYG50_RS19835
uniprot id: A0A345LZ07
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Monomer.

2027290:CYG50 RS00935
gene id: 2027290:CYG50_RS00935
uniprot id: A0A345LRE4
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.

2027290:CYG50 RS02085
gene id: 2027290:CYG50_RS02085
uniprot id: A0A345LX61
names: Similarity
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.

2027290:CYG50 RS18110
gene id: 2027290:CYG50_RS18110
uniprot id: A0A345LZW6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

2027290:CYG50 RS02260
gene id: 2027290:CYG50_RS02260
uniprot id: A0A345LX25
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
messages: Carbon 2 of the heme B porphyrin ring is defined according to the Fischer nomenclature.
messages: Cell membrane
messages: Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
messages: Membrane

2027290:CYG50 RS14975
gene id: 2027290:CYG50_RS14975
uniprot id: A0A345M1J1
names: Function
names: Similarity
messages: Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage.
messages: Belongs to the Nudix hydrolase family. RppH subfamily.

2027290:CYG50 RS12020
gene id: 2027290:CYG50_RS12020
uniprot id: A0A345LS16
names: Similarity
messages: Belongs to the adrenodoxin/putidaredoxin family.

2027290:CYG50 RS11370
gene id: 2027290:CYG50_RS11370
uniprot id: A0A345LSC9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 1 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 13 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.

2027290:CYG50 RS11500
gene id: 2027290:CYG50_RS11500
uniprot id: A0A345LSA5
names: Subcellular Location Annotation
messages: Membrane

2027290:CYG50 RS14860
gene id: 2027290:CYG50_RS14860
uniprot id: A0A345M1L0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0382 family.
messages: Membrane

2027290:CYG50 RS20570
gene id: 2027290:CYG50_RS20570
uniprot id: A0A345LYM9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GlpE family.
messages: Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide.
messages: Cytoplasm

2027290:CYG50 RS04905
gene id: 2027290:CYG50_RS04905
uniprot id: A0A345LVN9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GhoT/OrtT toxin family.
messages: Cell inner membrane
messages: Membrane

2027290:CYG50 RS18195
gene id: 2027290:CYG50_RS18195
uniprot id: A0A345LZU9
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

2027290:CYG50 RS01900
gene id: 2027290:CYG50_RS01900
uniprot id: A0A345LXA1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetate uptake transporter (AceTr) (TC 2.A.96) family.
messages: Membrane

2027290:CYG50 RS14745
gene id: 2027290:CYG50_RS14745
uniprot id: A0A345M1N2
names: Similarity
messages: Belongs to the skp family.

2027290:CYG50 RS11380
gene id: 2027290:CYG50_RS11380
uniprot id: A0A345LSC8
names: Function
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.

2027290:CYG50 RS14170
gene id: 2027290:CYG50_RS14170
uniprot id: A0A345M1Y6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DksA family.
messages: Cytoplasm
messages: Interacts directly with the RNA polymerase.
messages: Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters. Also required for regulation of fis expression.

2027290:CYG50 RS06295
gene id: 2027290:CYG50_RS06295
uniprot id: A0A345LUY9
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

2027290:CYG50 RS04295
gene id: 2027290:CYG50_RS04295
uniprot id: A0A345LW09
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dCTP deaminase family.
messages: Catalyzes the deamination of dCTP to dUTP.
messages: Homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2027290:CYG50 RS12955
gene id: 2027290:CYG50_RS12955
uniprot id: A0A345M2L3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.
messages: Cell membrane
messages: Self-interacts. Interacts with FtsZ.

2027290:CYG50 RS17565
gene id: 2027290:CYG50_RS17565
uniprot id: A0A345M055
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with bS18 to 16S ribosomal RNA.

2027290:CYG50 RS16500
gene id: 2027290:CYG50_RS16500
uniprot id: A0A345M0P9
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

2027290:CYG50 RS00300
gene id: 2027290:CYG50_RS00300
uniprot id: A0A345LR33
names: Similarity
messages: Belongs to the site-specific recombinase resolvase family.

2027290:CYG50 RS09325
gene id: 2027290:CYG50_RS09325
uniprot id: A0A345LTF2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

2027290:CYG50 RS14640
gene id: 2027290:CYG50_RS14640
uniprot id: A0A345M1Q2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nlpA lipoprotein family.
messages: Membrane

2027290:CYG50 RS04180
gene id: 2027290:CYG50_RS04180
uniprot id: A0A345LW31
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family.
messages: Homopolymer.
messages: Toroid-shaped homodecamer, composed of two pentamers of five dimers.

2027290:CYG50 RS05415
gene id: 2027290:CYG50_RS05415
uniprot id: A0A345LVF3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

2027290:CYG50 RS21200
gene id: 2027290:CYG50_RS21200
uniprot id: A0A345LYB2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

2027290:CYG50 RS21195
gene id: 2027290:CYG50_RS21195
uniprot id: A0A345LYB3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

2027290:CYG50 RS00645
gene id: 2027290:CYG50_RS00645
uniprot id: A0A345LR95
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Bcr/CmlA family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

2027290:CYG50 RS03830
gene id: 2027290:CYG50_RS03830
uniprot id: A0A345LW98
names: Cofactor
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Binds 1 [3Fe-4S] cluster.
messages: Binds 1 [4Fe-4S] cluster.

2027290:CYG50 RS06005
gene id: 2027290:CYG50_RS06005
uniprot id: A0A345LV45
names: Subcellular Location Annotation
messages: Membrane

2027290:CYG50 RS20575
gene id: 2027290:CYG50_RS20575
uniprot id: A0A345LYM8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NfuA family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is presumably bound at the interface of two monomers.
messages: Homodimer.
messages: Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins.

2027290:CYG50 RS01300
gene id: 2027290:CYG50_RS01300
uniprot id: A0A345LRL1
names: Similarity
messages: Belongs to the aminoglycoside phosphotransferase family.

2027290:CYG50 RS18175
gene id: 2027290:CYG50_RS18175
uniprot id: A0A345LZV3
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

2027290:CYG50 RS15600
gene id: 2027290:CYG50_RS15600
uniprot id: A0A345M172
names: Similarity
messages: Belongs to the GST superfamily. HSP26 family.

2027290:CYG50 RS11990
gene id: 2027290:CYG50_RS11990
uniprot id: A0A345LS21
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

2027290:CYG50 RS12950
gene id: 2027290:CYG50_RS12950
uniprot id: A0A345M2L4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

2027290:CYG50 RS06290
gene id: 2027290:CYG50_RS06290
uniprot id: A0A345LUZ0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

2027290:CYG50 RS19910
gene id: 2027290:CYG50_RS19910
uniprot id: A0A345LYZ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal stress protein A family.
messages: Cytoplasm

2027290:CYG50 RS01265
gene id: 2027290:CYG50_RS01265
uniprot id: A0A345LRK5
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

2027290:CYG50 RS02115
gene id: 2027290:CYG50_RS02115
uniprot id: A0A345LX55
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

2027290:CYG50 RS19380
gene id: 2027290:CYG50_RS19380
uniprot id: A0A345LZ89
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type B subfamily.
messages: Part of the 50S ribosomal subunit.

2027290:CYG50 RS18210
gene id: 2027290:CYG50_RS18210
uniprot id: A0A345LZU6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

2027290:CYG50 RS05530
gene id: 2027290:CYG50_RS05530
uniprot id: A0A345LVC9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliN/MopA/SpaO family.
messages: Cell membrane
messages: FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
messages: Membrane

2027290:CYG50 RS09590
gene id: 2027290:CYG50_RS09590
uniprot id: A0A345LTA4
names: Similarity
messages: Belongs to the UPF0181 family.

2027290:CYG50 RS02010
gene id: 2027290:CYG50_RS02010
uniprot id: A0A345LX79
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

2027290:CYG50 RS15710
gene id: 2027290:CYG50_RS15710
uniprot id: A0A345M150
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RapZ-like family. RapZ subfamily.
messages: Homotrimer.
messages: Modulates the synthesis of GlmS, by affecting the processing and stability of the regulatory small RNA GlmZ. When glucosamine-6-phosphate (GlcN6P) concentrations are high in the cell, RapZ binds GlmZ and targets it to cleavage by RNase E. Consequently, GlmZ is inactivated and unable to activate GlmS synthesis. Under low GlcN6P concentrations, RapZ is sequestered and inactivated by an other regulatory small RNA, GlmY, preventing GlmZ degradation and leading to synthesis of GlmS.

2027290:CYG50 RS01100
gene id: 2027290:CYG50_RS01100
uniprot id: A0A345LRH4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbC subfamily.
messages: Periplasm
messages: Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process.

2027290:CYG50 RS18115
gene id: 2027290:CYG50_RS18115
uniprot id: A0A345LZW5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

2027290:CYG50 RS01350
gene id: 2027290:CYG50_RS01350
uniprot id: A0A345LRA2
names: Function
messages: Involved in the transposition of the insertion sequence.

2027290:CYG50 RS21465
gene id: 2027290:CYG50_RS21465
uniprot id: A0A345LY60
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

2027290:CYG50 RS00385
gene id: 2027290:CYG50_RS00385
uniprot id: A0A345LR49
names: Subcellular Location Annotation
messages: Membrane

2027290:CYG50 RS11385
gene id: 2027290:CYG50_RS11385
uniprot id: A0A345LSC7
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.

2027290:CYG50 RS10695
gene id: 2027290:CYG50_RS10695
uniprot id: A0A345LSQ3
names: Cofactor
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

2027290:CYG50 RS18200
gene id: 2027290:CYG50_RS18200
uniprot id: A0A345LZU8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

2027290:CYG50 RS14340
gene id: 2027290:CYG50_RS14340
uniprot id: A0A345M1V5
names: Similarity
messages: Belongs to the UPF0423 family.

2027290:CYG50 RS14145
gene id: 2027290:CYG50_RS14145
uniprot id: A0A345M1Z1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HesB/IscA family.
messages: Binds 1 iron-sulfur cluster per subunit.
messages: Homodimer.
messages: Required for insertion of 4Fe-4S clusters for at least IspG.

2027290:CYG50 RS15605
gene id: 2027290:CYG50_RS15605
uniprot id: A0A345M171
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

2027290:CYG50 RS15620
gene id: 2027290:CYG50_RS15620
uniprot id: A0A345M168
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZapG family.
messages: Cell inner membrane
messages: Membrane

2027290:CYG50 RS16165
gene id: 2027290:CYG50_RS16165
uniprot id: A0A345M0W2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

2027290:CYG50 RS01505
gene id: 2027290:CYG50_RS01505
uniprot id: A0A345LXH7
names: Similarity
messages: Belongs to the CbbQ/NirQ/NorQ/GpvN family.

2027290:CYG50 RS18170
gene id: 2027290:CYG50_RS18170
uniprot id: A0A345LZV4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

2027290:CYG50 RS01295
gene id: 2027290:CYG50_RS01295
uniprot id: A0A345LRL0
names: Function
names: Similarity
messages: Belongs to the DHPS family.
messages: Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives.

2027290:CYG50 RS03560
gene id: 2027290:CYG50_RS03560
uniprot id: A0A345LWE1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

2027290:CYG50 RS07220
gene id: 2027290:CYG50_RS07220
uniprot id: A0A345LUH8
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

2027290:CYG50 RS04125
gene id: 2027290:CYG50_RS04125
uniprot id: A0A345LW41
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

2027290:CYG50 RS05595
gene id: 2027290:CYG50_RS05595
uniprot id: A0A345LVB7
names: Similarity
messages: Belongs to the EcnA/EcnB lipoprotein family.

2027290:CYG50 RS01490
gene id: 2027290:CYG50_RS01490
uniprot id: A0A345LXI0
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2027290:CYG50 RS08065
gene id: 2027290:CYG50_RS08065
uniprot id: A0A345LU28
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

2027290:CYG50 RS00670
gene id: 2027290:CYG50_RS00670
uniprot id: A0A345LRA0
names: Function
names: Similarity
messages: Belongs to the dihydrofolate reductase family.
messages: Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.

2027290:CYG50 RS04960
gene id: 2027290:CYG50_RS04960
uniprot id: A0A345LVN0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dsrC/tusE family.
messages: Cytoplasm
messages: Interacts with the TusBCD complex. Interacts with MnmA.
messages: Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Could accept sulfur from TusD.

2027290:CYG50 RS11520
gene id: 2027290:CYG50_RS11520
uniprot id: A0A345M2S5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Membrane

2027290:CYG50 RS04165
gene id: 2027290:CYG50_RS04165
uniprot id: A0A345M307
names: Similarity
messages: Belongs to the YjdM family.

2027290:CYG50 RS14735
gene id: 2027290:CYG50_RS14735
uniprot id: A0A345M1N4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioester dehydratase family. FabZ subfamily.
messages: Cytoplasm
messages: Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.

2027290:CYG50 RS12015
gene id: 2027290:CYG50_RS12015
uniprot id: A0A345LS17
names: Function
names: Similarity
messages: Belongs to the IscX family.
messages: May function as iron donor in the assembly of iron-sulfur clusters.

2027290:CYG50 RS00595
gene id: 2027290:CYG50_RS00595
uniprot id: A0A345LR85
names: Similarity
messages: Belongs to the site-specific recombinase resolvase family.

2027290:CYG50 RS11625
gene id: 2027290:CYG50_RS11625
uniprot id: A0A345LS82
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmB subfamily.
messages: Methylates ribosomal protein uL3 on a specific glutamine residue.

2027290:CYG50 RS03815
gene id: 2027290:CYG50_RS03815
uniprot id: A0A345LWA1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome b560 family.
messages: Membrane
messages: Membrane-anchoring subunit of succinate dehydrogenase (SDH).
messages: Part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur protein, plus two membrane-anchoring proteins, SdhC and SdhD. The complex can form homotrimers.
messages: The heme is bound between the two transmembrane subunits.

2027290:CYG50 RS06185
gene id: 2027290:CYG50_RS06185
uniprot id: A0A345LV10
names: Subcellular Location Annotation
messages: Membrane

2027290:CYG50 RS17260
gene id: 2027290:CYG50_RS17260
uniprot id: A0A345M0A6
names: Similarity
messages: Belongs to the RelB/DinJ antitoxin family.

2027290:CYG50 RS16285
gene id: 2027290:CYG50_RS16285
uniprot id: A0A345M0T9
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial microcompartment
messages: Belongs to the bacterial microcompartments protein family.

2027290:CYG50 RS12750
gene id: 2027290:CYG50_RS12750
uniprot id: A0A345M2Q0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

2027290:CYG50 RS03880
gene id: 2027290:CYG50_RS03880
uniprot id: A0A345LW88
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ExbB/TolQ family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity. Required, with TolR, for the proton motive force-dependent activation of TolA and for TolA-Pal interaction.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

2027290:CYG50 RS19105
gene id: 2027290:CYG50_RS19105
uniprot id: A0A345LZE0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the nucleoid occlusion factor SlmA family.
messages: Homodimer. Interacts with FtsZ.
messages: Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid. Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers. SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions.
messages: nucleoid

2027290:CYG50 RS03810
gene id: 2027290:CYG50_RS03810
uniprot id: A0A345LWA2
names: Similarity
messages: Belongs to the citrate synthase family.

2027290:CYG50 RS15610
gene id: 2027290:CYG50_RS15610
uniprot id: A0A345M170
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

2027290:CYG50 RS18090
gene id: 2027290:CYG50_RS18090
uniprot id: A0A345LZX0
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

2027290:CYG50 RS19530
gene id: 2027290:CYG50_RS19530
uniprot id: A0A345LZ59
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

2027290:CYG50 RS02280
gene id: 2027290:CYG50_RS02280
uniprot id: A0A345LX21
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome c oxidase subunit 2 family.
messages: Cell membrane
messages: Cytochrome bo(3) ubiquinol terminal oxidase is the component of the aerobic respiratory chain of E.coli that predominates when cells are grown at high aeration. Has proton pump activity across the membrane in addition to electron transfer, pumping 2 protons/electron.
messages: Heterooctamer of two A chains, two B chains, two C chains and two D chains.
messages: Membrane

2027290:CYG50 RS06080
gene id: 2027290:CYG50_RS06080
uniprot id: A0A345LV30
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

2027290:CYG50 RS02365
gene id: 2027290:CYG50_RS02365
uniprot id: A0A345LX04
names: Similarity
messages: Belongs to the P(II) protein family.

2027290:CYG50 RS14040
gene id: 2027290:CYG50_RS14040
uniprot id: A0A345M211
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

2027290:CYG50 RS22660
gene id: 2027290:CYG50_RS22660
uniprot id: A0A345LXK4
names: Function
names: Similarity
messages: Belongs to the dihydrofolate reductase family.
messages: Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.

2027290:CYG50 RS20790
gene id: 2027290:CYG50_RS20790
uniprot id: A0A345LYI9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glutamine synthetase family.
messages: Catalyzes the ATP-dependent biosynthesis of glutamine from glutamate and ammonia.
messages: Cytoplasm
messages: Oligomer of 12 subunits arranged in the form of two hexagons.

2027290:CYG50 RS17205
gene id: 2027290:CYG50_RS17205
uniprot id: A0A345M0B6
names: Similarity
messages: Belongs to the RutC family.

2027290:CYG50 RS22705
gene id: 2027290:CYG50_RS22705
uniprot id: A0A345LXJ7
names: Similarity
messages: Belongs to the class-A beta-lactamase family.

2027290:CYG50 RS11235
gene id: 2027290:CYG50_RS11235
uniprot id: A0A345LSF6
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the RcsB family.
messages: Component of the Rcs signaling system, which controls transcription of numerous genes. RcsB is the response regulator that binds to regulatory DNA regions.
messages: Interacts with RcsD.
messages: Phosphorylated and activated by RcsD.

2027290:CYG50 RS04560
gene id: 2027290:CYG50_RS04560
uniprot id: A0A345LVV6
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

2027290:CYG50 RS13355
gene id: 2027290:CYG50_RS13355
uniprot id: A0A345M2E0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NapF family.
messages: Could be involved in the maturation of NapA, the catalytic subunit of the periplasmic nitrate reductase, before its export into the periplasm.
messages: Cytoplasm
messages: Interacts with the cytoplasmic NapA precursor.

2027290:CYG50 RS17605
gene id: 2027290:CYG50_RS17605
uniprot id: A0A345M047
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

2027290:CYG50 RS18190
gene id: 2027290:CYG50_RS18190
uniprot id: A0A345LZV0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

2027290:CYG50 RS21600
gene id: 2027290:CYG50_RS21600
uniprot id: A0A345LY40
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S24 family.
messages: Homodimer.
messages: Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. Binds to the 16 bp palindromic sequence 5'-CTGTATATATATACAG-3'. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.

2027290:CYG50 RS18105
gene id: 2027290:CYG50_RS18105
uniprot id: A0A345LZW7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

2027290:CYG50 RS19560
gene id: 2027290:CYG50_RS19560
uniprot id: A0A345LZ53
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Membrane

2027290:CYG50 RS16230
gene id: 2027290:CYG50_RS16230
uniprot id: A0A345M0V0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

2027290:CYG50 RS12385
gene id: 2027290:CYG50_RS12385
uniprot id: A0A345LRU8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

2027290:CYG50 RS04430
gene id: 2027290:CYG50_RS04430
uniprot id: A0A345LVY2
names: Similarity
names: Subunit
messages: Belongs to the glutaredoxin family.
messages: Monomer.

2027290:CYG50 RS11355
gene id: 2027290:CYG50_RS11355
uniprot id: A0A345LSD2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 13 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

2027290:CYG50 RS19455
gene id: 2027290:CYG50_RS19455
uniprot id: A0A345LZ73
names: Function
names: Similarity
messages: Belongs to the dihydrofolate reductase family.
messages: Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.

2027290:CYG50 RS18085
gene id: 2027290:CYG50_RS18085
uniprot id: A0A345LZX1
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

2027290:CYG50 RS02275
gene id: 2027290:CYG50_RS02275
uniprot id: A0A345LX22
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Membrane
messages: The cytochrome bo(3) ubiquinol oxidase complex is a heterooctamer of two A chains, two B chains, two C chains and two D chains.

2027290:CYG50 RS16280
gene id: 2027290:CYG50_RS16280
uniprot id: A0A345M0U0
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial microcompartment
messages: Belongs to the bacterial microcompartments protein family.

2027290:CYG50 RS17360
gene id: 2027290:CYG50_RS17360
uniprot id: A0A345M093
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

2027290:CYG50 RS11985
gene id: 2027290:CYG50_RS11985
uniprot id: A0A345M2S1
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity.

2027290:CYG50 RS15785
gene id: 2027290:CYG50_RS15785
uniprot id: A0A345M135
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MreD family.
messages: Cell inner membrane
messages: Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins.
messages: Membrane

2027290:CYG50 RS18460
gene id: 2027290:CYG50_RS18460
uniprot id: A0A345LZQ8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ZapB family.
messages: Cytoplasm
messages: Homodimer. The ends of the coiled-coil dimer bind to each other, forming polymers. Interacts with FtsZ.
messages: Non-essential, abundant cell division factor that is required for proper Z-ring formation. It is recruited early to the divisome by direct interaction with FtsZ, stimulating Z-ring assembly and thereby promoting cell division earlier in the cell cycle. Its recruitment to the Z-ring requires functional FtsA or ZipA.

2027290:CYG50 RS01315
gene id: 2027290:CYG50_RS01315
uniprot id: A0A345LR86
names: Similarity
messages: Belongs to the class-A beta-lactamase family.

2027290:CYG50 RS21310
gene id: 2027290:CYG50_RS21310
uniprot id: A0A345LY90
names: Subcellular Location Annotation
messages: Membrane

2027290:CYG50 RS06855
gene id: 2027290:CYG50_RS06855
uniprot id: A0A345LUN7
names: Subcellular Location Annotation
messages: Membrane

2027290:CYG50 RS19750
gene id: 2027290:CYG50_RS19750
uniprot id: A0A345LZ23
names: Subcellular Location Annotation
messages: Membrane

2027290:CYG50 RS03595
gene id: 2027290:CYG50_RS03595
uniprot id: A0A345LWD4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Membrane

2027290:CYG50 RS04765
gene id: 2027290:CYG50_RS04765
uniprot id: A0A345LVR6
names: Similarity
messages: Belongs to the UPF0434 family.

2027290:CYG50 RS09440
gene id: 2027290:CYG50_RS09440
uniprot id: A0A345LTD0
names: Function
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
messages: Catalyzes the oxidative phosphorylation of glyceraldehyde 3-phosphate (G3P) to 1,3-bisphosphoglycerate (BPG) using the cofactor NAD. The first reaction step involves the formation of a hemiacetal intermediate between G3P and a cysteine residue, and this hemiacetal intermediate is then oxidized to a thioester, with concomitant reduction of NAD to NADH. The reduced NADH is then exchanged with the second NAD, and the thioester is attacked by a nucleophilic inorganic phosphate to produce BPG.

2027290:CYG50 RS19755
gene id: 2027290:CYG50_RS19755
uniprot id: A0A345LZ22
names: Similarity
messages: Belongs to the universal stress protein A family.

2027290:CYG50 RS09285
gene id: 2027290:CYG50_RS09285
uniprot id: A0A345LTF9
names: Similarity
messages: Belongs to the UPF0057 (PMP3) family.

2027290:CYG50 RS18965
gene id: 2027290:CYG50_RS18965
uniprot id: A0A345LZG5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecB family.
messages: Cytoplasm
messages: Homotetramer, a dimer of dimers. One homotetramer interacts with 1 SecA dimer.
messages: One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA.

2027290:CYG50 RS16695
gene id: 2027290:CYG50_RS16695
uniprot id: A0A345M0L1
names: Subcellular Location Annotation
messages: Membrane

2027290:CYG50 RS19565
gene id: 2027290:CYG50_RS19565
uniprot id: A0A345LZ52
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase A chain family.
messages: Cell membrane
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

2027290:CYG50 RS19315
gene id: 2027290:CYG50_RS19315
uniprot id: A0A345LZA2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Cell membrane
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

2027290:CYG50 RS16490
gene id: 2027290:CYG50_RS16490
uniprot id: A0A8I2AD47
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

2027290:CYG50 RS09625
gene id: 2027290:CYG50_RS09625
uniprot id: A0A345LT98
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0266 family.
messages: Cell membrane
messages: Membrane

2027290:CYG50 RS12135
gene id: 2027290:CYG50_RS12135
uniprot id: A0A345LRZ4
names: Similarity
messages: Belongs to the P(II) protein family.

2027290:CYG50 RS03845
gene id: 2027290:CYG50_RS03845
uniprot id: A0A345LW95
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

2027290:CYG50 RS15730
gene id: 2027290:CYG50_RS15730
uniprot id: A0A345M146
names: Similarity
messages: Belongs to the UPF0307 family.

2027290:CYG50 RS15340
gene id: 2027290:CYG50_RS15340
uniprot id: A0A345M1C0
names: Similarity
messages: Belongs to the HupF/HypC family.

2027290:CYG50 RS15175
gene id: 2027290:CYG50_RS15175
uniprot id: A0A345M1F3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

2027290:CYG50 RS01610
gene id: 2027290:CYG50_RS01610
uniprot id: A0A345LXF6
names: Function
messages: Functions in complex with FlhC as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region. Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes. Also regulates genes whose products function in a variety of physiological pathways.

2027290:CYG50 RS15840
gene id: 2027290:CYG50_RS15840
uniprot id: A0A345M126
names: Function
names: Similarity
names: Subunit
messages: Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters.
messages: Belongs to the transcriptional regulatory Fis family.
messages: Homodimer.

2027290:CYG50 RS18955
gene id: 2027290:CYG50_RS18955
uniprot id: A0A345LZG7
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

2027290:CYG50 RS04670
gene id: 2027290:CYG50_RS04670
uniprot id: A0A345LVT5
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Fur family.
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.

2027290:CYG50 RS06685
gene id: 2027290:CYG50_RS06685
uniprot id: A0A345LUR6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A highly abundant outer membrane lipoprotein that controls the distance between the inner and outer membranes. The only protein known to be covalently linked to the peptidoglycan network (PGN). Also non-covalently binds the PGN. The link between the cell outer membrane and PGN contributes to maintenance of the structural and functional integrity of the cell envelope, and maintains the correct distance between the PGN and the outer membrane.
messages: Belongs to the Lpp family.
messages: Cell outer membrane
messages: Homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: cell wall

2027290:CYG50 RS17630
gene id: 2027290:CYG50_RS17630
uniprot id: A0A345M042
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm

2027290:CYG50 RS13930
gene id: 2027290:CYG50_RS13930
uniprot id: A0A345M231
names: Similarity
messages: Belongs to the band 7/mec-2 family.

2027290:CYG50 RS02220
gene id: 2027290:CYG50_RS02220
uniprot id: A0A345LX33
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

2027290:CYG50 RS17390
gene id: 2027290:CYG50_RS17390
uniprot id: A0A345M087
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

2027290:CYG50 RS22280
gene id: 2027290:CYG50_RS22280
uniprot id: A0A345LXR2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PNP/UDP phosphorylase family.
messages: Catalyzes the reversible phosphorylytic cleavage of uridine to uracil and ribose-1-phosphate.
messages: Cytoplasm

2027290:CYG50 RS17345
gene id: 2027290:CYG50_RS17345
uniprot id: A0A345M376
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

2027290:CYG50 RS00345
gene id: 2027290:CYG50_RS00345
uniprot id: A0A345LXJ0
names: Function
names: Similarity
messages: Belongs to the DHPS family.
messages: Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives.

2027290:CYG50 RS18330
gene id: 2027290:CYG50_RS18330
uniprot id: A0A345LZT3
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Homodimer.
messages: Represses the transcription of fabB, involved in unsaturated fatty acid (UFA) biosynthesis. By controlling UFA production, FabR directly influences the physical properties of the membrane bilayer.

2027290:CYG50 RS03900
gene id: 2027290:CYG50_RS03900
uniprot id: A0A345LW84
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Pal lipoprotein family.
messages: Cell outer membrane
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

2027290:CYG50 RS16290
gene id: 2027290:CYG50_RS16290
uniprot id: A0A345M0T8
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial microcompartment
messages: Belongs to the bacterial microcompartments protein family.

2027290:CYG50 RS06165
gene id: 2027290:CYG50_RS06165
uniprot id: A0A345LV13
names: Similarity
messages: Belongs to the UPF0339 family. Duplicated subfamily.

2027290:CYG50 RS12595
gene id: 2027290:CYG50_RS12595
uniprot id: A0A345LRQ9
names: Similarity
messages: Belongs to the FrmR/RcnR family.

2027290:CYG50 RS01345
gene id: 2027290:CYG50_RS01345
uniprot id: A0A345LRL9
names: Function
names: Similarity
messages: Belongs to the antibiotic N-acetyltransferase family.
messages: Resistance to antibiotics containing the 2-deoxy-streptamine ring including gentamicin, kanamycin, tobramycin, neomycin and apramycin.

2027290:CYG50 RS00295
gene id: 2027290:CYG50_RS00295
uniprot id: A0A345LR32
names: Similarity
messages: Belongs to the transposase 7 family.

2027290:CYG50 RS19080
gene id: 2027290:CYG50_RS19080
uniprot id: A0A345LZE3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

2027290:CYG50 RS19770
gene id: 2027290:CYG50_RS19770
uniprot id: A0A345LZ19
names: Similarity
messages: Belongs to the transposase 7 family.

2027290:CYG50 RS12795
gene id: 2027290:CYG50_RS12795
uniprot id: A0A345M2P2
names: Function
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

2027290:CYG50 RS18125
gene id: 2027290:CYG50_RS18125
uniprot id: A0A345LZW3
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

2027290:CYG50 RS06660
gene id: 2027290:CYG50_RS06660
uniprot id: A0A345LUS1
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

2027290:CYG50 RS00650
gene id: 2027290:CYG50_RS00650
uniprot id: A0A345LR96
names: Function
names: Similarity
messages: Belongs to the DHPS family.
messages: Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives.

2027290:CYG50 RS22655
gene id: 2027290:CYG50_RS22655
uniprot id: A0A345LXK5
names: Similarity
messages: Belongs to the class-D beta-lactamase family.

2027290:CYG50 RS16075
gene id: 2027290:CYG50_RS16075
uniprot id: A0A345M0Y0
names: Cofactor
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Binds 1 [3Fe-4S] cluster.
messages: Binds 1 [4Fe-4S] cluster.

2027290:CYG50 RS04535
gene id: 2027290:CYG50_RS04535
uniprot id: A0A345LVW1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

2027290:CYG50 RS03325
gene id: 2027290:CYG50_RS03325
uniprot id: A0A345LWI3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

2027290:CYG50 RS15325
gene id: 2027290:CYG50_RS15325
uniprot id: A0A345M1C3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SIMIBI class G3E GTPase family. UreG subfamily.
messages: Cytoplasm
messages: Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG.
messages: Homodimer. UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

2027290:CYG50 RS01935
gene id: 2027290:CYG50_RS01935
uniprot id: A0A345LX94
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

2027290:CYG50 RS14810
gene id: 2027290:CYG50_RS14810
uniprot id: A0A345M1M0
names: Similarity
messages: Belongs to the UPF0325 family.

2027290:CYG50 RS15300
gene id: 2027290:CYG50_RS15300
uniprot id: A0A345M1C8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the urease gamma subunit family.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

2027290:CYG50 RS02250
gene id: 2027290:CYG50_RS02250
uniprot id: A0A345LX27
names: Similarity
messages: Belongs to the UPF0234 family.

2027290:CYG50 RS21080
gene id: 2027290:CYG50_RS21080
uniprot id: A0A345LYD5
names: Similarity
messages: Belongs to the phosphoribulokinase family.

2027290:CYG50 RS18550
gene id: 2027290:CYG50_RS18550
uniprot id: A0A345LZP4
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

2027290:CYG50 RS18180
gene id: 2027290:CYG50_RS18180
uniprot id: A0A345LZV2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

2027290:CYG50 RS01030
gene id: 2027290:CYG50_RS01030
uniprot id: A0A345LRG0
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2027290:CYG50 RS19915
gene id: 2027290:CYG50_RS19915
uniprot id: A0A345LYZ2
names: Function
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
messages: Catalyzes the reversible oxidative deamination of glutamate to alpha-ketoglutarate and ammonia.

2027290:CYG50 RS00335
gene id: 2027290:CYG50_RS00335
uniprot id: A0A345LR40
names: Similarity
messages: Belongs to the bacterial reverse transcriptase family.

2027290:CYG50 RS00685
gene id: 2027290:CYG50_RS00685
uniprot id: A0A345LRA2
names: Function
messages: Involved in the transposition of the insertion sequence.

2027290:CYG50 RS16270
gene id: 2027290:CYG50_RS16270
uniprot id: A0A345M0U2
names: Similarity
messages: Belongs to the CcmL/EutN family.

2027290:CYG50 RS00630
gene id: 2027290:CYG50_RS00630
uniprot id: A0A345LR92
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. TCR/Tet family.
messages: Membrane
messages: Resistance to tetracycline by an active tetracycline efflux. This is an energy-dependent process that decreases the accumulation of the antibiotic in whole cells. This protein functions as a metal-tetracycline/H(+) antiporter.

2027290:CYG50 RS06845
gene id: 2027290:CYG50_RS06845
uniprot id: A0A345LUN9
names: Similarity
messages: Belongs to the PspA/IM30 family.

2027290:CYG50 RS01595
gene id: 2027290:CYG50_RS01595
uniprot id: A0A345LXF9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.
messages: Resistance to Hg(2+) in bacteria appears to be governed by a specialized system which includes mercuric reductase. MerA protein is responsible for volatilizing mercury as Hg(0).

2027290:CYG50 RS11395
gene id: 2027290:CYG50_RS11395
uniprot id: A0A345LSC5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 20 kDa subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Cell membrane
messages: NDH-1 is composed of 13 different subunits. Subunits NuoB, CD, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

2027290:CYG50 RS01575
gene id: 2027290:CYG50_RS01575
uniprot id: A0A345LXG3
names: Function
messages: Mediates the mercuric-dependent induction of mercury resistance operon. In the absence of mercury MerR represses transcription by binding tightly to the mer operator region; when mercury is present the dimeric complex binds a single ion and becomes a potent transcriptional activator, while remaining bound to the mer site.

2027290:CYG50 RS13330
gene id: 2027290:CYG50_RS13330
uniprot id: A0A345M2E5
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NapB family.
messages: Binds 2 heme C groups per subunit.
messages: Component of the periplasmic nitrate reductase NapAB complex composed of NapA and NapB.
messages: Electron transfer subunit of the periplasmic nitrate reductase complex NapAB.
messages: Periplasm

2027290:CYG50 RS18215
gene id: 2027290:CYG50_RS18215
uniprot id: A0A345LZU5
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: Methylated by PrmB.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

2027290:CYG50 RS16085
gene id: 2027290:CYG50_RS16085
uniprot id: A0A345M0X8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FrdD family.
messages: Cell membrane
messages: Part of an enzyme complex containing four subunits: a flavoprotein (FrdA), an iron-sulfur protein (FrdB), and two hydrophobic anchor proteins (FrdC and FrdD).
messages: Two distinct, membrane-bound, FAD-containing enzymes are responsible for the catalysis of fumarate and succinate interconversion; fumarate reductase is used in anaerobic growth, and succinate dehydrogenase is used in aerobic growth. Anchors the catalytic components of the fumarate reductase complex to the cell inner membrane, binds quinones.

2027290:CYG50 RS12040
gene id: 2027290:CYG50_RS12040
uniprot id: A0A345LS12
names: Function
names: Similarity
messages: A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters.
messages: Belongs to the NifU family.

2027290:CYG50 RS18810
gene id: 2027290:CYG50_RS18810
uniprot id: A0A345LZJ3
names: Subcellular Location Annotation
messages: Cell inner membrane

2027290:CYG50 RS06100
gene id: 2027290:CYG50_RS06100
uniprot id: A0A345LV26
names: Similarity
messages: Belongs to the SorC transcriptional regulatory family.

2027290:CYG50 RS18440
gene id: 2027290:CYG50_RS18440
uniprot id: A0A345LZR2
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: Allosterically activated by HslU binding.
messages: Belongs to the peptidase T1B family. HslV subfamily.
messages: Cytoplasm
messages: Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.

2027290:CYG50 RS09360
gene id: 2027290:CYG50_RS09360
uniprot id: A0A345LTE5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone-like protein H-NS family.
messages: nucleoid

2027290:CYG50 RS18205
gene id: 2027290:CYG50_RS18205
uniprot id: A0A345LZU7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

2027290:CYG50 RS02270
gene id: 2027290:CYG50_RS02270
uniprot id: A0A345LX23
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Cytochrome bo(3) ubiquinol terminal oxidase is the component of the aerobic respiratory chain of E.coli that predominates when cells are grown at high aeration. Has proton pump activity across the membrane in addition to electron transfer, pumping 2 protons/electron.
messages: Heterooctamer of two A chains, two B chains, two C chains and two D chains.
messages: Membrane

2027290:CYG50 RS11365
gene id: 2027290:CYG50_RS11365
uniprot id: A0A345LSD0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 23 kDa subunit family.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell membrane
messages: NDH-1 is composed of 13 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

2027290:CYG50 RS15795
gene id: 2027290:CYG50_RS15795
uniprot id: A0A345M133
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

2027290:CYG50 RS14780
gene id: 2027290:CYG50_RS14780
uniprot id: A0A345M1M6
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by GTP. Inhibited by UTP.
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2027290:CYG50 RS10865
gene id: 2027290:CYG50_RS10865
uniprot id: A0A345LSM1
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

2027290:CYG50 RS02105
gene id: 2027290:CYG50_RS02105
uniprot id: A0A345LX57
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YajC family.
messages: Cell inner membrane
messages: Membrane

2027290:CYG50 RS01040
gene id: 2027290:CYG50_RS01040
uniprot id: A0A345LRG2
names: Similarity
messages: Belongs to the CbbQ/NirQ/NorQ/GpvN family.

2027290:CYG50 RS09345
gene id: 2027290:CYG50_RS09345
uniprot id: A0A345LTE8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell membrane
messages: Membrane

2027290:CYG50 RS19740
gene id: 2027290:CYG50_RS19740
uniprot id: A0A345LZ25
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ArsB family.
messages: Cell membrane
messages: Involved in arsenical resistance. Thought to form the channel of an arsenite pump.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

2027290:CYG50 RS12085
gene id: 2027290:CYG50_RS12085
uniprot id: A0A345LS03
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

2027290:CYG50 RS01585
gene id: 2027290:CYG50_RS01585
uniprot id: A0A345LXG1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MerP family.
messages: Involved in mercury resistance. Acts as a mercury scavenger that specifically binds to a mercuric ion in the periplasm and probably passes it to the cytoplasmic mercuric reductase MerA via the mercuric transport protein MerT.
messages: Monomer.
messages: Periplasm

2027290:CYG50 RS07800
gene id: 2027290:CYG50_RS07800
uniprot id: A0A345LU74
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

2027290:CYG50 RS12345
gene id: 2027290:CYG50_RS12345
uniprot id: A0A345LRV4
names: Function
messages: Acts as a radical domain for damaged PFL and possibly other radical proteins.

2027290:CYG50 RS03520
gene id: 2027290:CYG50_RS03520
uniprot id: A0A345LWE9
names: Subcellular Location Annotation
messages: Cytoplasm

2027290:CYG50 RS18095
gene id: 2027290:CYG50_RS18095
uniprot id: A0A345LZW9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

2027290:CYG50 RS01425
gene id: 2027290:CYG50_RS01425
uniprot id: A0A345LXJ0
names: Function
names: Similarity
messages: Belongs to the DHPS family.
messages: Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives.

2027290:CYG50 RS10940
gene id: 2027290:CYG50_RS10940
uniprot id: A0A345LSK8
names: Similarity
messages: Belongs to the UPF0265 family.

2027290:CYG50 RS11350
gene id: 2027290:CYG50_RS11350
uniprot id: A0A345LSD3
names: Subcellular Location Annotation
messages: Membrane

2027290:CYG50 RS19745
gene id: 2027290:CYG50_RS19745
uniprot id: A0A345LZ24
names: Similarity
messages: Belongs to the ArsC family.

2027290:CYG50 RS18160
gene id: 2027290:CYG50_RS18160
uniprot id: A0A345LZV6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

2027290:CYG50 RS15210
gene id: 2027290:CYG50_RS15210
uniprot id: A0A345M1E6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HdeB family.
messages: Periplasm
messages: Required for optimal acid stress protection, which is important for survival of enteric bacteria in the acidic environment of the host stomach. Exhibits a chaperone-like activity at acidic pH by preventing the aggregation of many different periplasmic proteins.

2027290:CYG50 RS01385
gene id: 2027290:CYG50_RS01385
uniprot id: A0A345LRM6
names: Similarity
messages: Belongs to the ner transcriptional regulatory family.

2027290:CYG50 RS02695
gene id: 2027290:CYG50_RS02695
uniprot id: A0A345LWU5
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

2027290:CYG50 RS19075
gene id: 2027290:CYG50_RS19075
uniprot id: A0A345LZE4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

2027290:CYG50 RS11065
gene id: 2027290:CYG50_RS11065
uniprot id: A0A345LSI4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

2027290:CYG50 RS20635
gene id: 2027290:CYG50_RS20635
uniprot id: A0A345LYL7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Membrane

2027290:CYG50 RS04585
gene id: 2027290:CYG50_RS04585
uniprot id: A0A345LVV1
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2027290:CYG50 RS02775
gene id: 2027290:CYG50_RS02775
uniprot id: A0A345LWT0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmB/CycW/HelB family.
messages: Cell inner membrane
messages: Membrane
messages: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.

2027290:CYG50 RS17320
gene id: 2027290:CYG50_RS17320
uniprot id: A0A345M098
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

2027290:CYG50 RS03025
gene id: 2027290:CYG50_RS03025
uniprot id: A0A345LWN5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Fe(2+)-trafficking protein family.
messages: Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes.
messages: Monomer.

2027290:CYG50 RS00655
gene id: 2027290:CYG50_RS00655
uniprot id: A0A345LR97
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

2027290:CYG50 RS03490
gene id: 2027290:CYG50_RS03490
uniprot id: A0A345LWF5
names: Similarity
messages: Belongs to the ABC transporter superfamily.

2027290:CYG50 RS17340
gene id: 2027290:CYG50_RS17340
uniprot id: A0A345M094
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

2027290:CYG50 RS18165
gene id: 2027290:CYG50_RS18165
uniprot id: A0A345LZV5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

2027290:CYG50 RS01580
gene id: 2027290:CYG50_RS01580
uniprot id: A0A345LXG2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MerT family.
messages: Cell inner membrane
messages: Membrane

2027290:CYG50 RS02825
gene id: 2027290:CYG50_RS02825
uniprot id: A0A345LWS3
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

2027290:CYG50 RS19330
gene id: 2027290:CYG50_RS19330
uniprot id: A0A345LZ99
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

2027290:CYG50 RS02235
gene id: 2027290:CYG50_RS02235
uniprot id: A0A345LX30
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the hok/gef family.
messages: Cell inner membrane

2027290:CYG50 RS12035
gene id: 2027290:CYG50_RS12035
uniprot id: A0A345LS13
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HesB/IscA family.
messages: Binds 2 iron ions per dimer. The dimer may bind additional iron ions.
messages: Homodimer; may form tetramers and higher multimers.
messages: Is able to transfer iron-sulfur clusters to apo-ferredoxin. Multiple cycles of [2Fe2S] cluster formation and transfer are observed, suggesting that IscA acts catalytically. Recruits intracellular free iron so as to provide iron for the assembly of transient iron-sulfur cluster in IscU in the presence of IscS, L-cysteine and the thioredoxin reductase system TrxA/TrxB.

2027290:CYG50 RS18185
gene id: 2027290:CYG50_RS18185
uniprot id: A0A345LZV1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

2027290:CYG50 RS02230
gene id: 2027290:CYG50_RS02230
uniprot id: A0A345LX30
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the hok/gef family.
messages: Cell inner membrane

2027290:CYG50 RS22665
gene id: 2027290:CYG50_RS22665
uniprot id: A0A345LR97
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

2027290:CYG50 RS03820
gene id: 2027290:CYG50_RS03820
uniprot id: A0A345LWA0
names: Cofactor
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane
messages: Membrane-anchoring subunit of succinate dehydrogenase (SDH).
messages: The heme is bound between the two transmembrane subunits.

2027290:CYG50 RS16050
gene id: 2027290:CYG50_RS16050
uniprot id: A0A345M0Y5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Composed of a catalytic GlpA/B dimer and of membrane bound GlpC.
messages: Membrane

2027290:CYG50 RS11310
gene id: 2027290:CYG50_RS11310
uniprot id: A0A345LSE1
names: Caution
names: Function
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family. MenB subfamily.
messages: Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2-naphthoyl-CoA (DHNA-CoA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2027290:CYG50 RS14680
gene id: 2027290:CYG50_RS14680
uniprot id: A0A345M393
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane.

2027290:CYG50 RS01190
gene id: 2027290:CYG50_RS01190
uniprot id: A0A345LRJ2
names: Similarity
messages: Belongs to the type IA topoisomerase family.

2027290:CYG50 RS00700
gene id: 2027290:CYG50_RS00700
uniprot id: A0A345LRA4
names: Similarity
messages: Belongs to the site-specific recombinase resolvase family.

2027290:CYG50 RS11975
gene id: 2027290:CYG50_RS11975
uniprot id: A0A345LS23
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

2027290:CYG50 RS04675
gene id: 2027290:CYG50_RS04675
uniprot id: A0A345LVT4
names: Function
names: Similarity
messages: Belongs to the flavodoxin family.
messages: Low-potential electron donor to a number of redox enzymes.

2027290:CYG50 RS02310
gene id: 2027290:CYG50_RS02310
uniprot id: A0A345LX15
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

2027290:CYG50 RS12945
gene id: 2027290:CYG50_RS12945
uniprot id: A0A345M2L5
names: Function
names: Similarity
messages: Belongs to the LpxC family.
messages: Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.

2027290:CYG50 RS18220
gene id: 2027290:CYG50_RS18220
uniprot id: A0A345LZU4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

2027290:CYG50 RS06760
gene id: 2027290:CYG50_RS06760
uniprot id: A0A345LUQ5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the glyoxalase I family.
messages: Binds 1 nickel ion per subunit.
messages: Binds 1 zinc ion per subunit. In the homodimer, two zinc ions are bound between subunits.
messages: Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione.

2027290:CYG50 RS14555
gene id: 2027290:CYG50_RS14555
uniprot id: A0A345M1R3
names: Cofactor
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.
messages: Binds 1 zinc ion per subunit.

2027290:CYG50 RS18130
gene id: 2027290:CYG50_RS18130
uniprot id: A0A345LZW2
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

2027290:CYG50 RS18050
gene id: 2027290:CYG50_RS18050
uniprot id: A0A345LZX6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

2027290:CYG50 RS22670
gene id: 2027290:CYG50_RS22670
uniprot id: A0A345LXJ0
names: Function
names: Similarity
messages: Belongs to the DHPS family.
messages: Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives.

2027290:CYG50 RS00765
gene id: 2027290:CYG50_RS00765
uniprot id: A0A345LRB3
names: Similarity
messages: Belongs to the class-A beta-lactamase family.

2027290:CYG50 RS18145
gene id: 2027290:CYG50_RS18145
uniprot id: A0A345LZV9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

2027290:CYG50 RS13300
gene id: 2027290:CYG50_RS13300
uniprot id: A0A345M2F1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbE subfamily.
messages: Cell inner membrane

2027290:CYG50 RS11615
gene id: 2027290:CYG50_RS11615
uniprot id: A0A345LS84
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

2027290:CYG50 RS04890
gene id: 2027290:CYG50_RS04890
uniprot id: A0A345LVP2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ribosome modulation factor family.
messages: Cytoplasm
messages: During stationary phase, converts 70S ribosomes to an inactive dimeric form (100S ribosomes).

2027290:CYG50 RS19035
gene id: 2027290:CYG50_RS19035
uniprot id: A0A345LZF1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

2027290:CYG50 RS05220
gene id: 2027290:CYG50_RS05220
uniprot id: A0A345LVJ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MgtC/SapB family.
messages: Cell inner membrane
messages: Membrane

2027290:CYG50 RS06285
gene id: 2027290:CYG50_RS06285
uniprot id: A0A345LUZ1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-3 family.
messages: Cytoplasm
messages: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.
messages: Monomer.

2027290:CYG50 RS16370
gene id: 2027290:CYG50_RS16370
uniprot id: A0A8I2AP55
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

2027290:CYG50 RS03965
gene id: 2027290:CYG50_RS03965
uniprot id: A0A345LW73
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: AcrA-AcrB-AcrZ-TolC is a drug efflux protein complex with a broad substrate specificity. This protein binds to AcrB and is required for efflux of some but not all substrates, suggesting it may influence the specificity of drug export.
messages: Belongs to the AcrZ family.
messages: Cell membrane
messages: Part of the AcrA-AcrB-AcrZ-TolC efflux pump, interacts directly with AcrB.

2027290:CYG50 RS05630
gene id: 2027290:CYG50_RS05630
uniprot id: A0A345LVB0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliS family.
messages: cytosol

2027290:CYG50 RS22615
gene id: 2027290:CYG50_RS22615
uniprot id: A0A345LXK9
names: Similarity
messages: Belongs to the transposase 7 family.

2027290:CYG50 RS09615
gene id: 2027290:CYG50_RS09615
uniprot id: A0A345LTA0
names: Subcellular Location Annotation
messages: Membrane

2027290:CYG50 RS07795
gene id: 2027290:CYG50_RS07795
uniprot id: A0A345LU75
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family. MdtJ subfamily.
messages: Catalyzes the excretion of spermidine.
messages: Cell membrane
messages: Forms a complex with MdtI.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

2027290:CYG50 RS02130
gene id: 2027290:CYG50_RS02130
uniprot id: A0A345LX52
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.
messages: Forms an icosahedral capsid composed of 60 subunits, arranged as a dodecamer of pentamers.

2027290:CYG50 RS04355
gene id: 2027290:CYG50_RS04355
uniprot id: A0A345LVZ7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

2027290:CYG50 RS18420
gene id: 2027290:CYG50_RS18420
uniprot id: A0A345LZR6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

2027290:CYG50 RS12725
gene id: 2027290:CYG50_RS12725
uniprot id: A0A345M2Q5
names: Similarity
messages: Belongs to the SdhE FAD assembly factor family.

2027290:CYG50 RS07075
gene id: 2027290:CYG50_RS07075
uniprot id: A0A345LUK0
names: Function
messages: Electron transfer subunit of the terminal reductase during anaerobic growth on various sulfoxide and N-oxide compounds.

2027290:CYG50 RS05565
gene id: 2027290:CYG50_RS05565
uniprot id: A0A345LVC2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliG family.
messages: Cell inner membrane
messages: FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
messages: Membrane

2027290:CYG50 RS14505
gene id: 2027290:CYG50_RS14505
uniprot id: A0A345M1S3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IspF family.
messages: Binds 1 divalent metal cation per subunit.
messages: Homotrimer.
messages: Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).

2027290:CYG50 RS04895
gene id: 2027290:CYG50_RS04895
uniprot id: A0A345LVP1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thioester dehydratase family. FabA subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)-decenoyl-ACP. Can catalyze the dehydratase reaction for beta-hydroxyacyl-ACPs with saturated chain lengths up to 16:0, being most active on intermediate chain length.

2027290:CYG50 RS00315
gene id: 2027290:CYG50_RS00315
uniprot id: A0A345LR36
names: Similarity
messages: Belongs to the metallo-beta-lactamase superfamily. Class-B beta-lactamase family.

2027290:CYG50 RS01470
gene id: 2027290:CYG50_RS01470
uniprot id: A0A345LXI4
names: Subcellular Location Annotation
messages: Membrane

2027290:CYG50 RS18135
gene id: 2027290:CYG50_RS18135
uniprot id: A0A345LZW1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

2027290:CYG50 RS10890
gene id: 2027290:CYG50_RS10890
uniprot id: A0A345LSL7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

2027290:CYG50 RS00600
gene id: 2027290:CYG50_RS00600
uniprot id: A0A345LR86
names: Similarity
messages: Belongs to the class-A beta-lactamase family.

2027290:CYG50 RS00320
gene id: 2027290:CYG50_RS00320
uniprot id: A0A345LR37
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

2027290:CYG50 RS09065
gene id: 2027290:CYG50_RS09065
uniprot id: A0A345LTJ9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell inner membrane
messages: Membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

2027290:CYG50 RS16740
gene id: 2027290:CYG50_RS16740
uniprot id: A0A345M0K2
names: Subcellular Location Annotation
messages: Membrane

2027290:CYG50 RS18410
gene id: 2027290:CYG50_RS18410
uniprot id: A0A345LZR8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MetJ family.
messages: Cytoplasm
messages: Does not bind DNA by a helix-turn-helix motif.
messages: Homodimer.
messages: This regulatory protein, when combined with SAM (S-adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis.

2027290:CYG50 RS01680
gene id: 2027290:CYG50_RS01680
uniprot id: A0A345LXE2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PNP/UDP phosphorylase family.
messages: Catalyzes the reversible phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.
messages: Homohexamer; trimer of homodimers.

2027290:CYG50 RS21215
gene id: 2027290:CYG50_RS21215
uniprot id: A0A345LYA9
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2027290:CYG50 RS05310
gene id: 2027290:CYG50_RS05310
uniprot id: A0A345LVH3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MotA family.
messages: Membrane

2027290:CYG50 RS12920
gene id: 2027290:CYG50_RS12920
uniprot id: A0A345M2L9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA gyrase inhibitor YacG family.
messages: Binds 1 zinc ion.
messages: Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase.
messages: Interacts with GyrB.

2027290:CYG50 RS13315
gene id: 2027290:CYG50_RS13315
uniprot id: A0A345M2E8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmD/CycX/HelD family.
messages: Cell inner membrane
messages: Membrane
messages: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.

2027290:CYG50 RS14515
gene id: 2027290:CYG50_RS14515
uniprot id: A0A345M1S1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsB family.
messages: Cell inner membrane
messages: Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.
messages: Part of a complex composed of FtsB, FtsL and FtsQ.

2027290:CYG50 RS17405
gene id: 2027290:CYG50_RS17405
uniprot id: A0A345M084
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

2027290:CYG50 RS12305
gene id: 2027290:CYG50_RS12305
uniprot id: A0A345LRW2
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

2027290:CYG50 RS00340
gene id: 2027290:CYG50_RS00340
uniprot id: A0A345LR97
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

2027290:CYG50 RS03600
gene id: 2027290:CYG50_RS03600
uniprot id: A0A345M313
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

2027290:CYG50 RS18535
gene id: 2027290:CYG50_RS18535
uniprot id: A0A345LZP7
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by ADP and other diphosphonucleosides, and allosterically inhibited by phosphoenolpyruvate.
messages: Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Prokaryotic clade 'B1' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homotetramer.

2027290:CYG50 RS02135
gene id: 2027290:CYG50_RS02135
uniprot id: A0A345LX51
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

2027290:CYG50 RS05300
gene id: 2027290:CYG50_RS05300
uniprot id: A0A345LVH5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FlhD family.
messages: Cytoplasm
messages: Functions in complex with FlhC as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region. Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes. Also regulates genes whose products function in a variety of physiological pathways.
messages: Homodimer; disulfide-linked. Forms a heterohexamer composed of two FlhC and four FlhD subunits. Each FlhC binds a FlhD dimer, forming a heterotrimer, and a hexamer assembles by dimerization of two heterotrimers.
messages: The C-terminal region contains a putative helix-turn-helix (HTH) motif, suggesting that this region may bind DNA.

2027290:CYG50 RS15965
gene id: 2027290:CYG50_RS15965
uniprot id: A0A345M102
names: Similarity
messages: Belongs to the leucine-binding protein family.

2027290:CYG50 RS01275
gene id: 2027290:CYG50_RS01275
uniprot id: A0A345LRK7
names: Similarity
messages: Belongs to the ParB family.

2027290:CYG50 RS11855
gene id: 2027290:CYG50_RS11855
uniprot id: A0A345LS46
names: Subcellular Location Annotation
messages: Cytoplasm

2027290:CYG50 RS06315
gene id: 2027290:CYG50_RS06315
uniprot id: A0A345LUY6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial histone-like protein family.
messages: Heterodimer of an alpha and a beta chain.
messages: This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.

2027290:CYG50 RS00725
gene id: 2027290:CYG50_RS00725
uniprot id: A0A345LRA8
names: Similarity
messages: Belongs to the site-specific recombinase resolvase family.

2027290:CYG50 RS21225
gene id: 2027290:CYG50_RS21225
uniprot id: A0A345LYA7
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

2027290:CYG50 RS14200
gene id: 2027290:CYG50_RS14200
uniprot id: A0A345M1Y1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell inner membrane
messages: Membrane

2027290:CYG50 RS15990
gene id: 2027290:CYG50_RS15990
uniprot id: A0A345M0Z7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Homodimer. Forms a membrane-associated complex with FtsX.
messages: Part of the ABC transporter FtsEX involved in cellular division. Important for assembly or stability of the septal ring.

2027290:CYG50 RS20630
gene id: 2027290:CYG50_RS20630
uniprot id: A0A345M349
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

2027290:CYG50 RS00605
gene id: 2027290:CYG50_RS00605
uniprot id: A0A345LR87
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily. Aminoglycoside resistance family.
messages: Specifically methylates the N7 position of guanine 1405 in 16S rRNA. Confers resistance to various aminoglycosides.

2027290:CYG50 RS21220
gene id: 2027290:CYG50_RS21220
uniprot id: A0A345LYA8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NusG family.
messages: Monomer. Interacts with the transcription termination factor Rho and with RNA polymerase.
messages: Participates in transcription elongation, termination and antitermination. In the absence of Rho, increases the rate of transcription elongation by the RNA polymerase (RNAP), probably by partially suppressing pausing. In the presence of Rho, modulates most Rho-dependent termination events by interacting with the RNAP to render the complex more susceptible to the termination activity of Rho. May be required to overcome a kinetic limitation of Rho to function at certain terminators. Also involved in ribosomal RNA transcriptional antitermination.

2027290:CYG50 RS03980
gene id: 2027290:CYG50_RS03980
uniprot id: A0A345LW70
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane.

2027290:CYG50 RS10200
gene id: 2027290:CYG50_RS10200
uniprot id: A0A345LSZ9
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
messages: Allosterically activated by GTP.
messages: Belongs to the UPRTase family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.
messages: Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.

2027290:CYG50 RS15640
gene id: 2027290:CYG50_RS15640
uniprot id: A0A345M164
names: Similarity
messages: Belongs to the BolA/IbaG family.

2027290:CYG50 RS19555
gene id: 2027290:CYG50_RS19555
uniprot id: A0A345LZ54
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0). The b'-subunit is a diverged and duplicated form of b found in plants and photosynthetic bacteria.
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

2027290:CYG50 RS14785
gene id: 2027290:CYG50_RS14785
uniprot id: A0A345M1M5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

2027290:CYG50 RS02465
gene id: 2027290:CYG50_RS02465
uniprot id: A0A345LWY8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EcpA/MatB fimbrillin family.
messages: Fimbrium
messages: Self-associates. Forms filaments. Interacts with EcpD.

2027290:CYG50 RS18120
gene id: 2027290:CYG50_RS18120
uniprot id: A0A345LZW4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

2027290:CYG50 RS05435
gene id: 2027290:CYG50_RS05435
uniprot id: A0A345LVE9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

2027290:CYG50 RS22715
gene id: 2027290:CYG50_RS22715
uniprot id: A0A345LXJ5
names: Subcellular Location Annotation
messages: Membrane

2027290:CYG50 RS05210
gene id: 2027290:CYG50_RS05210
uniprot id: A0A345LVJ2
names: Subcellular Location Annotation
messages: Cytoplasm

2027290:CYG50 RS01780
gene id: 2027290:CYG50_RS01780
uniprot id: A0A345LXC3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the YjjX NTPase family.
messages: Binds 1 divalent metal cation per subunit; can use either Mg(2+) or Mn(2+).
messages: Homodimer.
messages: Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA/RNA precursor pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

2027290:CYG50 RS17435
gene id: 2027290:CYG50_RS17435
uniprot id: A0A345M078
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LDH/MDH superfamily. MDH type 1 family.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.
messages: Homodimer.

2027290:CYG50 RS03275
gene id: 2027290:CYG50_RS03275
uniprot id: A0A345LWI9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Mediates global changes in gene expression, shifting from rapid growth to stress survival by linking envelope stress, the stringent response and the catabolite repression systems. Usually binds in the 5'-UTR; binding at or near the Shine-Dalgarno sequence prevents ribosome-binding, repressing translation, binding elsewhere in the 5'-UTR can activate translation and/or stabilize the mRNA. Its function is antagonized by small RNA(s).
messages: Belongs to the CsrA/RsmA family.
messages: Cytoplasm
messages: Homodimer; the beta-strands of each monomer intercalate to form a hydrophobic core, while the alpha-helices form wings that extend away from the core.

2027290:CYG50 RS17555
gene id: 2027290:CYG50_RS17555
uniprot id: A0A345M057
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein bS6.

2027290:CYG50 RS04735
gene id: 2027290:CYG50_RS04735
uniprot id: A0A345LVS2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial histone-like protein family.
messages: Heterodimer of an alpha and a beta chain.
messages: This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.

2027290:CYG50 RS01465
gene id: 2027290:CYG50_RS01465
uniprot id: A0A345LXI5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

2027290:CYG50 RS12990
gene id: 2027290:CYG50_RS12990
uniprot id: A0A345M2K6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane
messages: Membrane

2027290:CYG50 RS04280
gene id: 2027290:CYG50_RS04280
uniprot id: A0A345LW12
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LemA family.
messages: Membrane

2027290:CYG50 RS03535
gene id: 2027290:CYG50_RS03535
uniprot id: A0A345LWE6
names: Similarity
messages: Belongs to the UPF0250 family.