2014:EL646 RS13255
gene id: 2014:EL646_RS13255
uniprot id: A0A223QIB4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

2014:EL646 RS20830
gene id: 2014:EL646_RS20830
uniprot id: A0A223Q7K8
names: Similarity
messages: Belongs to the UPF0336 family.

2014:EL646 RS23010
gene id: 2014:EL646_RS23010
uniprot id: A0A223Q8J5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NucS endonuclease family.
messages: Cleaves both 3' and 5' ssDNA extremities of branched DNA structures.
messages: Cytoplasm

2014:EL646 RS24590
gene id: 2014:EL646_RS24590
uniprot id: A0A223Q9K8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

2014:EL646 RS22055
gene id: 2014:EL646_RS22055
uniprot id: A0A223Q857
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

2014:EL646 RS23090
gene id: 2014:EL646_RS23090
uniprot id: A0A223Q8Y2
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

2014:EL646 RS08160
gene id: 2014:EL646_RS08160
uniprot id: A0A223QFD4
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2014:EL646 RS15225
gene id: 2014:EL646_RS15225
uniprot id: A0A223QJA9
names: Similarity
messages: Belongs to the PhoU family.
messages: Belongs to the UPF0111 family.

2014:EL646 RS21085
gene id: 2014:EL646_RS21085
uniprot id: A0A223Q7N5
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

2014:EL646 RS24910
gene id: 2014:EL646_RS24910
uniprot id: A0A223QA32
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.

2014:EL646 RS24660
gene id: 2014:EL646_RS24660
uniprot id: A0A223Q9F0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

2014:EL646 RS04680
gene id: 2014:EL646_RS04680
uniprot id: A0A223QDZ0
names: Similarity
messages: Belongs to the peptidase C40 family.

2014:EL646 RS19860
gene id: 2014:EL646_RS19860
uniprot id: A0A223Q736
names: Similarity
messages: Belongs to the UPF0337 (CsbD) family.

2014:EL646 RS10405
gene id: 2014:EL646_RS10405
uniprot id: A0A223QGJ6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2014:EL646 RS00800
gene id: 2014:EL646_RS00800
uniprot id: A0A223QBY5
names: Domain
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic ubiquitin-like protein family.
messages: Is modified by deamidation of its C-terminal glutamine to glutamate by the deamidase Dop, a prerequisite to the subsequent pupylation process.
messages: Protein modifier that is covalently attached to lysine residues of substrate proteins, thereby targeting them for proteasomal degradation. The tagging system is termed pupylation.
messages: Strongly interacts with the proteasome-associated ATPase ARC through a hydrophobic interface; the interacting region of Pup lies in its C-terminal half. There is one Pup binding site per ARC hexamer ring.
messages: The N-terminal unstructured half of Pup provides a signal required to initiate unfolding and degradation by the proteasome but is not needed for pupylation, while the C-terminal helical half of Pup interacts with ARC to target proteins to the proteasome.

2014:EL646 RS20985
gene id: 2014:EL646_RS20985
uniprot id: A0A223Q7V4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

2014:EL646 RS17190
gene id: 2014:EL646_RS17190
uniprot id: A0A223QLG2
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

2014:EL646 RS15985
gene id: 2014:EL646_RS15985
uniprot id: A0A223QJU8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

2014:EL646 RS08030
gene id: 2014:EL646_RS08030
uniprot id: A0A223QFR8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

2014:EL646 RS25635
gene id: 2014:EL646_RS25635
uniprot id: A0A223Q9Y8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Reduced FMN (FMNH(2)).

2014:EL646 RS18695
gene id: 2014:EL646_RS18695
uniprot id: A0A223Q6H3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRA-PH family.
messages: Cytoplasm

2014:EL646 RS20760
gene id: 2014:EL646_RS20760
uniprot id: A0A223Q7S2
names: Similarity
messages: Belongs to the UPF0234 family.

2014:EL646 RS00370
gene id: 2014:EL646_RS00370
uniprot id: A0A223QB80
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

2014:EL646 RS11610
gene id: 2014:EL646_RS11610
uniprot id: A0A223QHD4
names: Similarity
messages: Belongs to the FPG family.

2014:EL646 RS12755
gene id: 2014:EL646_RS12755
uniprot id: A0A223QHY8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.
messages: In the C-terminal section; belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: In the N-terminal section; belongs to the MIP18 family.

2014:EL646 RS24575
gene id: 2014:EL646_RS24575
uniprot id: A0A223Q9R0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecX family.
messages: Cytoplasm
messages: Modulates RecA activity.

2014:EL646 RS08320
gene id: 2014:EL646_RS08320
uniprot id: A0A223QFF9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
messages: Cytoplasm

2014:EL646 RS17670
gene id: 2014:EL646_RS17670
uniprot id: A0A223QLJ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0161 family.
messages: Cell membrane
messages: Could be involved in insertion of integral membrane proteins into the membrane.

2014:EL646 RS05095
gene id: 2014:EL646_RS05095
uniprot id: A0A223QDR0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the gas vesicle GvpA family.
messages: Gas vesicle shell
messages: Gas vesicles are hollow, gas filled proteinaceous nanostructures found in some microorganisms. During planktonic growth they allow positioning of the organism at a favorable depth for light or nutrient acquisition. GvpA forms the protein shell.
messages: The gas vesicle shell is 2 nm thick and consists of a single layer of this protein. It forms helical ribs nearly perpendicular to the long axis of the vesicle.

2014:EL646 RS13765
gene id: 2014:EL646_RS13765
uniprot id: A0A223QII2
names: Subcellular Location Annotation
messages: Membrane

2014:EL646 RS10080
gene id: 2014:EL646_RS10080
uniprot id: A0A223QGD4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

2014:EL646 RS13340
gene id: 2014:EL646_RS13340
uniprot id: A0A223QIE0
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

2014:EL646 RS22915
gene id: 2014:EL646_RS22915
uniprot id: A0A223Q8Y3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Membrane

2014:EL646 RS27510
gene id: 2014:EL646_RS27510
uniprot id: A0A223QB43
names: Subcellular Location Annotation
messages: Membrane

2014:EL646 RS08775
gene id: 2014:EL646_RS08775
uniprot id: A0A223QG39
names: Function
names: Similarity
names: Subunit
messages: Belongs to the OMP decarboxylase family. Type 1 subfamily.
messages: Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
messages: Homodimer.

2014:EL646 RS21050
gene id: 2014:EL646_RS21050
uniprot id: A0A223Q7T1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

2014:EL646 RS08170
gene id: 2014:EL646_RS08170
uniprot id: A0A223QFB3
names: Function
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.
messages: Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.

2014:EL646 RS27315
gene id: 2014:EL646_RS27315
uniprot id: A0A223QAT2
names: Similarity
messages: Belongs to the WXG100 family.

2014:EL646 RS11290
gene id: 2014:EL646_RS11290
uniprot id: A0A223QH87
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

2014:EL646 RS10365
gene id: 2014:EL646_RS10365
uniprot id: A0A223QGT0
names: Similarity
messages: Belongs to the LacAB/RpiB family.

2014:EL646 RS20865
gene id: 2014:EL646_RS20865
uniprot id: A0A223Q7U2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.

2014:EL646 RS18870
gene id: 2014:EL646_RS18870
uniprot id: A0A223Q6L2
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

2014:EL646 RS08785
gene id: 2014:EL646_RS08785
uniprot id: A0A223QGI9
names: Cofactor
names: Similarity
messages: Belongs to the PyrK family.
messages: Binds 1 FAD per subunit.
messages: Binds 1 [2Fe-2S] cluster per subunit.

2014:EL646 RS08155
gene id: 2014:EL646_RS08155
uniprot id: A0A223QFP6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 2 subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

2014:EL646 RS25120
gene id: 2014:EL646_RS25120
uniprot id: A0A223QA50
names: Function
names: Similarity
messages: Belongs to the LDH/MDH superfamily. MDH type 2 family.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.

2014:EL646 RS13170
gene id: 2014:EL646_RS13170
uniprot id: A0A223QI66
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Nucleus membrane

2014:EL646 RS10745
gene id: 2014:EL646_RS10745
uniprot id: A0A223QHC3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 2 subfamily.
messages: Cytoplasm
messages: Homotetramer.

2014:EL646 RS05975
gene id: 2014:EL646_RS05975
uniprot id: A0A223QE76
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

2014:EL646 RS20850
gene id: 2014:EL646_RS20850
uniprot id: A0A223Q7L5
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.

2014:EL646 RS07915
gene id: 2014:EL646_RS07915
uniprot id: A0A223QF62
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

2014:EL646 RS22380
gene id: 2014:EL646_RS22380
uniprot id: A0A223Q8N1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

2014:EL646 RS08765
gene id: 2014:EL646_RS08765
uniprot id: A0A223QFL7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

2014:EL646 RS07470
gene id: 2014:EL646_RS07470
uniprot id: A0A223QFB2
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

2014:EL646 RS24885
gene id: 2014:EL646_RS24885
uniprot id: A0A223Q9J4
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

2014:EL646 RS12120
gene id: 2014:EL646_RS12120
uniprot id: A0A223QHK6
names: Similarity
messages: Belongs to the UPF0434 family.

2014:EL646 RS22105
gene id: 2014:EL646_RS22105
uniprot id: A0A223Q863
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

2014:EL646 RS18615
gene id: 2014:EL646_RS18615
uniprot id: A0A223Q6F8
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

2014:EL646 RS17555
gene id: 2014:EL646_RS17555
uniprot id: A0A223QKG8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein bS6.

2014:EL646 RS17560
gene id: 2014:EL646_RS17560
uniprot id: A0A223QKH2
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2014:EL646 RS12340
gene id: 2014:EL646_RS12340
uniprot id: A0A223QHQ3
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: Nucleus
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

2014:EL646 RS08630
gene id: 2014:EL646_RS08630
uniprot id: A0A223QG19
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

2014:EL646 RS09255
gene id: 2014:EL646_RS09255
uniprot id: A0A223QG96
names: Similarity
messages: Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily.

2014:EL646 RS13745
gene id: 2014:EL646_RS13745
uniprot id: A0A223QIT4
names: Similarity
messages: Belongs to the UDPGP type 2 family.

2014:EL646 RS10310
gene id: 2014:EL646_RS10310
uniprot id: A0A223QGN7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

2014:EL646 RS09980
gene id: 2014:EL646_RS09980
uniprot id: A0A223QL67
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

2014:EL646 RS01110
gene id: 2014:EL646_RS01110
uniprot id: A0A223QC32
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

2014:EL646 RS22865
gene id: 2014:EL646_RS22865
uniprot id: A0A223Q8X1
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2014:EL646 RS25295
gene id: 2014:EL646_RS25295
uniprot id: A0A223Q9X9
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

2014:EL646 RS22875
gene id: 2014:EL646_RS22875
uniprot id: A0A223Q8T1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

2014:EL646 RS09995
gene id: 2014:EL646_RS09995
uniprot id: A0A223QG91
names: Similarity
messages: Belongs to the CFA/CMAS family.

2014:EL646 RS23185
gene id: 2014:EL646_RS23185
uniprot id: A0A223QKQ1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase PH family.
messages: Homohexameric ring arranged as a trimer of dimers.
messages: Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.

2014:EL646 RS20920
gene id: 2014:EL646_RS20920
uniprot id: A0A223Q7U4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

2014:EL646 RS18670
gene id: 2014:EL646_RS18670
uniprot id: A0A223Q6I0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2014:EL646 RS22115
gene id: 2014:EL646_RS22115
uniprot id: A0A223Q852
names: Function
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

2014:EL646 RS00670
gene id: 2014:EL646_RS00670
uniprot id: A0A223QBS8
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

2014:EL646 RS08790
gene id: 2014:EL646_RS08790
uniprot id: A0A223QFL4
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2014:EL646 RS08040
gene id: 2014:EL646_RS08040
uniprot id: A0A223QG42
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

2014:EL646 RS15355
gene id: 2014:EL646_RS15355
uniprot id: A0A223QJC7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
messages: Cytoplasm
messages: Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2014:EL646 RS23695
gene id: 2014:EL646_RS23695
uniprot id: A0A223Q8W6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

2014:EL646 RS20950
gene id: 2014:EL646_RS20950
uniprot id: A0A223Q7P9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

2014:EL646 RS06025
gene id: 2014:EL646_RS06025
uniprot id: A0A223QE90
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2014:EL646 RS15840
gene id: 2014:EL646_RS15840
uniprot id: A0A223QJK7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

2014:EL646 RS12820
gene id: 2014:EL646_RS12820
uniprot id: A0A223QIE6
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

2014:EL646 RS25665
gene id: 2014:EL646_RS25665
uniprot id: A0A223QA43
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

2014:EL646 RS09245
gene id: 2014:EL646_RS09245
uniprot id: A0A223QGR5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferritin family. Prokaryotic subfamily.
messages: Cytoplasm
messages: Iron-storage protein.

2014:EL646 RS25655
gene id: 2014:EL646_RS25655
uniprot id: A0A223QAA5
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

2014:EL646 RS09570
gene id: 2014:EL646_RS09570
uniprot id: A0A223QGF5
names: Similarity
messages: Belongs to the CsoR family.

2014:EL646 RS20945
gene id: 2014:EL646_RS20945
uniprot id: A0A223Q7P8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

2014:EL646 RS22190
gene id: 2014:EL646_RS22190
uniprot id: A0A223Q8I6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 1 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

2014:EL646 RS15190
gene id: 2014:EL646_RS15190
uniprot id: A0A223QJB8
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetyltransferase family. MshD subfamily.
messages: Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

2014:EL646 RS17495
gene id: 2014:EL646_RS17495
uniprot id: A0A223QKN9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2).
messages: Homodimer.

2014:EL646 RS14295
gene id: 2014:EL646_RS14295
uniprot id: A0A223QIQ0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cell surface
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
messages: capsule
messages: cell wall

2014:EL646 RS02720
gene id: 2014:EL646_RS02720
uniprot id: A0A223QCQ3
names: Subcellular Location Annotation
messages: Cytoplasm

2014:EL646 RS25690
gene id: 2014:EL646_RS25690
uniprot id: A0A223QA62
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MraZ family.
messages: Forms oligomers.
messages: nucleoid

2014:EL646 RS24745
gene id: 2014:EL646_RS24745
uniprot id: A0A223Q9K0
names: Function
names: Similarity
messages: Belongs to the HrcA family.
messages: Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons.

2014:EL646 RS15165
gene id: 2014:EL646_RS15165
uniprot id: A0A223QJA3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transcriptional regulatory Rex family.
messages: Cytoplasm
messages: Homodimer.
messages: Modulates transcription in response to changes in cellular NADH/NAD(+) redox state.

2014:EL646 RS11785
gene id: 2014:EL646_RS11785
uniprot id: A0A223QHW2
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

2014:EL646 RS19080
gene id: 2014:EL646_RS19080
uniprot id: A0A223Q6P7
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

2014:EL646 RS25465
gene id: 2014:EL646_RS25465
uniprot id: A0A223Q9W1
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

2014:EL646 RS08925
gene id: 2014:EL646_RS08925
uniprot id: A0A223QFY6
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

2014:EL646 RS09040
gene id: 2014:EL646_RS09040
uniprot id: A0A223QFU4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

2014:EL646 RS21695
gene id: 2014:EL646_RS21695
uniprot id: A0A223Q814
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

2014:EL646 RS08560
gene id: 2014:EL646_RS08560
uniprot id: A0A223QFI2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ArgR family.
messages: Cytoplasm
messages: Regulates arginine biosynthesis genes.

2014:EL646 RS12675
gene id: 2014:EL646_RS12675
uniprot id: A0A223QHY1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

2014:EL646 RS19590
gene id: 2014:EL646_RS19590
uniprot id: A0A223Q6Z0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

2014:EL646 RS20150
gene id: 2014:EL646_RS20150
uniprot id: A0A223Q787
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

2014:EL646 RS07445
gene id: 2014:EL646_RS07445
uniprot id: A0A223QL59
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the uroporphyrinogen decarboxylase family.
messages: Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2014:EL646 RS20330
gene id: 2014:EL646_RS20330
uniprot id: A0A223Q7D1
names: Similarity
messages: Belongs to the histone deacetylase family.

2014:EL646 RS10300
gene id: 2014:EL646_RS10300
uniprot id: A0A223QGR2
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

2014:EL646 RS02945
gene id: 2014:EL646_RS02945
uniprot id: A0A223QCP4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

2014:EL646 RS14405
gene id: 2014:EL646_RS14405
uniprot id: A0A223QIY6
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

2014:EL646 RS25595
gene id: 2014:EL646_RS25595
uniprot id: A0A223QA95
names: Similarity
messages: Belongs to the YciI family.

2014:EL646 RS18145
gene id: 2014:EL646_RS18145
uniprot id: A0A223Q678
names: Similarity
names: Subunit
messages: Belongs to the Bpa family.
messages: Forms a homooligomeric, either hexameric or heptameric, ring-like structure which stacks co-axially with the proteasomal alpha-rings.

2014:EL646 RS22400
gene id: 2014:EL646_RS22400
uniprot id: A0A223Q8G4
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

2014:EL646 RS26015
gene id: 2014:EL646_RS26015
uniprot id: A0A223QAE1
names: Similarity
messages: Belongs to the PspA/IM30 family.

2014:EL646 RS26430
gene id: 2014:EL646_RS26430
uniprot id: A0A223QKV3
names: Similarity
messages: Belongs to the thioesterase family.

2014:EL646 RS21000
gene id: 2014:EL646_RS21000
uniprot id: A0A223Q7Q8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

2014:EL646 RS15430
gene id: 2014:EL646_RS15430
uniprot id: A0A223QJE9
names: Subcellular Location Annotation
messages: Membrane

2014:EL646 RS16005
gene id: 2014:EL646_RS16005
uniprot id: A0A223QJN3
names: Subcellular Location Annotation
messages: Membrane

2014:EL646 RS25640
gene id: 2014:EL646_RS25640
uniprot id: A0A223QA53
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

2014:EL646 RS18700
gene id: 2014:EL646_RS18700
uniprot id: A0A223QKK9
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP phosphoribosyltransferase family. Long subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Feedback inhibited by histidine.

2014:EL646 RS17360
gene id: 2014:EL646_RS17360
uniprot id: A0A223QKB8
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta chain.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.

2014:EL646 RS21070
gene id: 2014:EL646_RS21070
uniprot id: A0A223Q7S6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

2014:EL646 RS00930
gene id: 2014:EL646_RS00930
uniprot id: A0A223QBI6
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanD family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
messages: Cytoplasm
messages: Heterooctamer of four alpha and four beta subunits.
messages: Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus.

2014:EL646 RS10110
gene id: 2014:EL646_RS10110
uniprot id: A0A223QH36
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein uL14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein uL14 (rplN).

2014:EL646 RS20575
gene id: 2014:EL646_RS20575
uniprot id: A0A223Q7G3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 20 kDa subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

2014:EL646 RS16845
gene id: 2014:EL646_RS16845
uniprot id: A0A223QK33
names: Subcellular Location Annotation
messages: Membrane

2014:EL646 RS22185
gene id: 2014:EL646_RS22185
uniprot id: A0A223Q8C3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

2014:EL646 RS09190
gene id: 2014:EL646_RS09190
uniprot id: A0A223QFU9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PRA-CH family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.
messages: Cytoplasm
messages: Homodimer.

2014:EL646 RS18845
gene id: 2014:EL646_RS18845
uniprot id: A0A223Q6J7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FGAMS family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

2014:EL646 RS13110
gene id: 2014:EL646_RS13110
uniprot id: A0A223QI56
names: Cofactor
names: Similarity
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

2014:EL646 RS20570
gene id: 2014:EL646_RS20570
uniprot id: A0A223QKN5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 3 family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

2014:EL646 RS11355
gene id: 2014:EL646_RS11355
uniprot id: A0A223QH75
names: Similarity
messages: Belongs to the GPN-loop GTPase family.

2014:EL646 RS09065
gene id: 2014:EL646_RS09065
uniprot id: A0A223QFZ6
names: Subcellular Location Annotation
messages: Membrane

2014:EL646 RS16515
gene id: 2014:EL646_RS16515
uniprot id: A0A223QJY2
names: Similarity
messages: Belongs to the SAICAR synthetase family.

2014:EL646 RS20995
gene id: 2014:EL646_RS20995
uniprot id: A0A223Q7R7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

2014:EL646 RS18855
gene id: 2014:EL646_RS18855
uniprot id: A0A223Q6K0
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

2014:EL646 RS13440
gene id: 2014:EL646_RS13440
uniprot id: A0A223QIC0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

2014:EL646 RS20220
gene id: 2014:EL646_RS20220
uniprot id: A0A223Q7B0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2014:EL646 RS11595
gene id: 2014:EL646_RS11595
uniprot id: A0A223QHB6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

2014:EL646 RS07535
gene id: 2014:EL646_RS07535
uniprot id: A0A223QEZ5
names: Subcellular Location Annotation
messages: Membrane

2014:EL646 RS24525
gene id: 2014:EL646_RS24525
uniprot id: A0A223Q9Q1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

2014:EL646 RS20620
gene id: 2014:EL646_RS20620
uniprot id: A0A223Q7I3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

2014:EL646 RS10445
gene id: 2014:EL646_RS10445
uniprot id: A0A223QGU8
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.
messages: Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).
messages: The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.
messages: The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1.

2014:EL646 RS25725
gene id: 2014:EL646_RS25725
uniprot id: A0A223QAE8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane
messages: Membrane

2014:EL646 RS14980
gene id: 2014:EL646_RS14980
uniprot id: A0A223QJ54
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyltransferase group 1 family. MshA subfamily.
messages: Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2-acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway.
messages: Homodimer.

2014:EL646 RS01850
gene id: 2014:EL646_RS01850
uniprot id: A0A223QC74
names: Similarity
messages: Belongs to the CsoR family.

2014:EL646 RS04525
gene id: 2014:EL646_RS04525
uniprot id: A0A223QDL8
names: Similarity
messages: Belongs to the arginase family. Agmatinase subfamily.

2014:EL646 RS26515
gene id: 2014:EL646_RS26515
uniprot id: A0A223QAE3
names: Cofactor
messages: Binds 1 Mg(2+) ion per subunit.

2014:EL646 RS17025
gene id: 2014:EL646_RS17025
uniprot id: A0A223QKE4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

2014:EL646 RS26385
gene id: 2014:EL646_RS26385
uniprot id: A0A223QAL4
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 zinc ion per subunit.

2014:EL646 RS08400
gene id: 2014:EL646_RS08400
uniprot id: A0A223QFP4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2014:EL646 RS19000
gene id: 2014:EL646_RS19000
uniprot id: A0A223Q6P1
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

2014:EL646 RS06190
gene id: 2014:EL646_RS06190
uniprot id: A0A223QF84
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

2014:EL646 RS15195
gene id: 2014:EL646_RS15195
uniprot id: A0A223QJF0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

2014:EL646 RS19515
gene id: 2014:EL646_RS19515
uniprot id: A0A223QKL8
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

2014:EL646 RS17200
gene id: 2014:EL646_RS17200
uniprot id: A0A223QKA2
names: Similarity
messages: Belongs to the asp23 family.

2014:EL646 RS24530
gene id: 2014:EL646_RS24530
uniprot id: A0A223Q9W5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

2014:EL646 RS01975
gene id: 2014:EL646_RS01975
uniprot id: A0A223QC52
names: Subcellular Location Annotation
messages: Membrane

2014:EL646 RS24700
gene id: 2014:EL646_RS24700
uniprot id: A0A223Q9W4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

2014:EL646 RS08095
gene id: 2014:EL646_RS08095
uniprot id: A0A223QF97
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

2014:EL646 RS03155
gene id: 2014:EL646_RS03155
uniprot id: A0A223QCU8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase H family.
messages: Binds 1 Mg(2+) ion per subunit. May bind a second metal ion at a regulatory site, or after substrate binding.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Monomer.

2014:EL646 RS08310
gene id: 2014:EL646_RS08310
uniprot id: A0A223QFU0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

2014:EL646 RS21745
gene id: 2014:EL646_RS21745
uniprot id: A0A223Q823
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2014:EL646 RS10120
gene id: 2014:EL646_RS10120
uniprot id: A0A223QGP5
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

2014:EL646 RS21005
gene id: 2014:EL646_RS21005
uniprot id: A0A223Q7N0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

2014:EL646 RS21740
gene id: 2014:EL646_RS21740
uniprot id: A0A223Q7Z8
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

2014:EL646 RS10765
gene id: 2014:EL646_RS10765
uniprot id: A0A223QGR6
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

2014:EL646 RS09220
gene id: 2014:EL646_RS09220
uniprot id: A0A223QG43
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

2014:EL646 RS01120
gene id: 2014:EL646_RS01120
uniprot id: A0A223QC54
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

2014:EL646 RS24890
gene id: 2014:EL646_RS24890
uniprot id: A0A223Q9R7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.

2014:EL646 RS20695
gene id: 2014:EL646_RS20695
uniprot id: A0A223Q7I7
names: Subcellular Location Annotation
messages: Cytoplasm

2014:EL646 RS20930
gene id: 2014:EL646_RS20930
uniprot id: A0A223Q7L8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

2014:EL646 RS11435
gene id: 2014:EL646_RS11435
uniprot id: A0A223QHC4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

2014:EL646 RS13135
gene id: 2014:EL646_RS13135
uniprot id: A0A223QIK6
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.

2014:EL646 RS14955
gene id: 2014:EL646_RS14955
uniprot id: A0A223QJ52
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

2014:EL646 RS22315
gene id: 2014:EL646_RS22315
uniprot id: A0A223Q8H3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

2014:EL646 RS09940
gene id: 2014:EL646_RS09940
uniprot id: A0A223QG84
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S24 family.
messages: Homodimer.
messages: Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.

2014:EL646 RS26555
gene id: 2014:EL646_RS26555
uniprot id: A0A223QAF1
names: Similarity
messages: Belongs to the RelA/SpoT family.

2014:EL646 RS20560
gene id: 2014:EL646_RS20560
uniprot id: A0A223Q7H8
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2).

2014:EL646 RS15035
gene id: 2014:EL646_RS15035
uniprot id: A0A223QJ58
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CobB/CobQ family. GatD subfamily.
messages: Forms a heterodimer with MurT.
messages: The lipid II isoglutaminyl synthase complex catalyzes the formation of alpha-D-isoglutamine in the cell wall lipid II stem peptide. The GatD subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia. The resulting ammonia molecule is channeled to the active site of MurT.

2014:EL646 RS23335
gene id: 2014:EL646_RS23335
uniprot id: A0A223Q9A2
names: Function
names: Similarity
messages: Belongs to the PurU family.
messages: Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).

2014:EL646 RS11935
gene id: 2014:EL646_RS11935
uniprot id: A0A223QHP1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Homodimer. Forms a membrane-associated complex with FtsX.
messages: Part of the ABC transporter FtsEX involved in cellular division.

2014:EL646 RS10215
gene id: 2014:EL646_RS10215
uniprot id: A0A223QH42
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

2014:EL646 RS10510
gene id: 2014:EL646_RS10510
uniprot id: A0A223QGW2
names: Similarity
messages: Belongs to the band 7/mec-2 family.

2014:EL646 RS17710
gene id: 2014:EL646_RS17710
uniprot id: A0A223Q603
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Binds two Mg(2+) per subunit. The magnesium ions form salt bridges with both the protein and the DNA. Can also accept other divalent metal cations, such as Mn(2+) or Ca(2+).
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

2014:EL646 RS07645
gene id: 2014:EL646_RS07645
uniprot id: A0A223QFB5
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

2014:EL646 RS16485
gene id: 2014:EL646_RS16485
uniprot id: A0A223QJW2
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2014:EL646 RS22125
gene id: 2014:EL646_RS22125
uniprot id: A0A223Q8H6
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

2014:EL646 RS17635
gene id: 2014:EL646_RS17635
uniprot id: A0A223QKL5
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

2014:EL646 RS21885
gene id: 2014:EL646_RS21885
uniprot id: A0A223Q842
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

2014:EL646 RS21010
gene id: 2014:EL646_RS21010
uniprot id: A0A223QKR8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

2014:EL646 RS21370
gene id: 2014:EL646_RS21370
uniprot id: A0A223Q7T4
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

2014:EL646 RS15240
gene id: 2014:EL646_RS15240
uniprot id: A0A223QJA5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

2014:EL646 RS04505
gene id: 2014:EL646_RS04505
uniprot id: A0A223QE68
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

2014:EL646 RS09020
gene id: 2014:EL646_RS09020
uniprot id: A0A223QGN2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associates with subunits I, II and III to form cytochrome c oxidase.
messages: Belongs to the cytochrome c oxidase bacterial subunit CtaF family.
messages: Cell membrane
messages: Membrane
messages: Part of cytochrome c oxidase, its function is unknown.

2014:EL646 RS21440
gene id: 2014:EL646_RS21440
uniprot id: A0A223Q7V3
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

2014:EL646 RS21065
gene id: 2014:EL646_RS21065
uniprot id: A0A223Q7N9
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

2014:EL646 RS19145
gene id: 2014:EL646_RS19145
uniprot id: A0A223Q6R5
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

2014:EL646 RS20825
gene id: 2014:EL646_RS20825
uniprot id: A0A223Q7S9
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

2014:EL646 RS18770
gene id: 2014:EL646_RS18770
uniprot id: A0A223Q6I1
names: Subcellular Location Annotation
messages: Membrane

2014:EL646 RS22895
gene id: 2014:EL646_RS22895
uniprot id: A0A223Q8H1
names: Subcellular Location Annotation
messages: Membrane

2014:EL646 RS13430
gene id: 2014:EL646_RS13430
uniprot id: A0A223QLB1
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

2014:EL646 RS14960
gene id: 2014:EL646_RS14960
uniprot id: A0A223QJ62
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

2014:EL646 RS23175
gene id: 2014:EL646_RS23175
uniprot id: A0A223Q8W7
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

2014:EL646 RS17405
gene id: 2014:EL646_RS17405
uniprot id: A0A223QKE6
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

2014:EL646 RS14900
gene id: 2014:EL646_RS14900
uniprot id: A0A223QJ38
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

2014:EL646 RS17410
gene id: 2014:EL646_RS17410
uniprot id: A0A223QKG5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

2014:EL646 RS13920
gene id: 2014:EL646_RS13920
uniprot id: A0A223QIH8
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CoA-transferase III family. Frc subfamily.
messages: Homodimer.
messages: Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2014:EL646 RS22290
gene id: 2014:EL646_RS22290
uniprot id: A0A223Q868
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

2014:EL646 RS17565
gene id: 2014:EL646_RS17565
uniprot id: A0A223QKF9
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with bS18 to 16S ribosomal RNA.

2014:EL646 RS13205
gene id: 2014:EL646_RS13205
uniprot id: A0A223QI88
names: Similarity
messages: Belongs to the PAPS reductase family. CysD subfamily.

2014:EL646 RS09230
gene id: 2014:EL646_RS09230
uniprot id: A0A223QL51
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

2014:EL646 RS16505
gene id: 2014:EL646_RS16505
uniprot id: A0A223QJW6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

2014:EL646 RS11500
gene id: 2014:EL646_RS11500
uniprot id: A0A223QHC1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

2014:EL646 RS23500
gene id: 2014:EL646_RS23500
uniprot id: A0A223Q951
names: Similarity
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.

2014:EL646 RS21990
gene id: 2014:EL646_RS21990
uniprot id: A0A223Q825
names: Similarity
messages: Belongs to the thymidine kinase family.

2014:EL646 RS20925
gene id: 2014:EL646_RS20925
uniprot id: A0A223Q7L6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

2014:EL646 RS20880
gene id: 2014:EL646_RS20880
uniprot id: A0A223Q7T8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

2014:EL646 RS13245
gene id: 2014:EL646_RS13245
uniprot id: A0A223QIM6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

2014:EL646 RS01115
gene id: 2014:EL646_RS01115
uniprot id: A0A223QBS4
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type B subfamily.
messages: Part of the 50S ribosomal subunit.

2014:EL646 RS07365
gene id: 2014:EL646_RS07365
uniprot id: A0A223QEW8
names: Function
messages: Catalyzes the reduction of sulfite to sulfide, a step in the biosynthesis of sulfur-containing amino acids and cofactors.

2014:EL646 RS23390
gene id: 2014:EL646_RS23390
uniprot id: A0A223Q8X8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2014:EL646 RS20960
gene id: 2014:EL646_RS20960
uniprot id: A0A223Q7M6
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

2014:EL646 RS13655
gene id: 2014:EL646_RS13655
uniprot id: A0A223QID2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
messages: Monomer.

2014:EL646 RS24780
gene id: 2014:EL646_RS24780
uniprot id: A0A223Q9H1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

2014:EL646 RS12835
gene id: 2014:EL646_RS12835
uniprot id: A0A223QI82
names: Cofactor
names: Function
messages: Binds 1 [3Fe-4S] cluster.
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

2014:EL646 RS07070
gene id: 2014:EL646_RS07070
uniprot id: A0A223QEQ5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase-binding protein RbpA family.
messages: Bind 1 Zn(2+) per subunit.
messages: Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters.
messages: Forms a complex with the RNAP catalytic core and with free principal sigma factors.

2014:EL646 RS19770
gene id: 2014:EL646_RS19770
uniprot id: A0A223Q732
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

2014:EL646 RS15075
gene id: 2014:EL646_RS15075
uniprot id: A0A223QJ78
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

2014:EL646 RS22910
gene id: 2014:EL646_RS22910
uniprot id: A0A223Q8R0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase A chain family.
messages: Cell membrane
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

2014:EL646 RS20890
gene id: 2014:EL646_RS20890
uniprot id: A0A223Q7L1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

2014:EL646 RS08890
gene id: 2014:EL646_RS08890
uniprot id: A0A223QGL0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThiI family.
messages: Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.
messages: Cytoplasm

2014:EL646 RS12150
gene id: 2014:EL646_RS12150
uniprot id: A0A223QHQ0
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

2014:EL646 RS02565
gene id: 2014:EL646_RS02565
uniprot id: A0A223QCF4
names: Similarity
messages: Belongs to the manganese catalase family.

2014:EL646 RS14140
gene id: 2014:EL646_RS14140
uniprot id: A0A223QIP5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DtxR/MntR family.
messages: Cytoplasm
messages: Homodimer.

2014:EL646 RS13530
gene id: 2014:EL646_RS13530
uniprot id: A0A223QIB3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaD and TsaB. TsaE seems to play an indirect role in the t(6)A biosynthesis pathway, possibly in regulating the core enzymatic function of TsaD.

2014:EL646 RS11270
gene id: 2014:EL646_RS11270
uniprot id: A0A223QHA6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

2014:EL646 RS25770
gene id: 2014:EL646_RS25770
uniprot id: A0A223QA64
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SepF family.
messages: Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA.
messages: Cytoplasm
messages: Homodimer. Interacts with FtsZ.

2014:EL646 RS24975
gene id: 2014:EL646_RS24975
uniprot id: A0A223Q9S6
names: Similarity
messages: Belongs to the dGTPase family. Type 2 subfamily.

2014:EL646 RS21015
gene id: 2014:EL646_RS21015
uniprot id: A0A223Q7N1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

2014:EL646 RS02575
gene id: 2014:EL646_RS02575
uniprot id: A0A223QCS1
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

2014:EL646 RS04265
gene id: 2014:EL646_RS04265
uniprot id: A0A223QE25
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Amino acid transporter (AAT) (TC 2.A.3.1) family.
messages: Membrane

2014:EL646 RS24475
gene id: 2014:EL646_RS24475
uniprot id: A0A223Q9P1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

2014:EL646 RS23270
gene id: 2014:EL646_RS23270
uniprot id: A0A223Q995
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

2014:EL646 RS16015
gene id: 2014:EL646_RS16015
uniprot id: A0A223QJL3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

2014:EL646 RS24325
gene id: 2014:EL646_RS24325
uniprot id: A0A223Q9F8
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

2014:EL646 RS23095
gene id: 2014:EL646_RS23095
uniprot id: A0A223Q960
names: Similarity
messages: Belongs to the UPF0301 (AlgH) family.

2014:EL646 RS07075
gene id: 2014:EL646_RS07075
uniprot id: A0A223QF60
names: Cofactor
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.
messages: Divalent metal ions. Mg(2+) is the most effective.

2014:EL646 RS09095
gene id: 2014:EL646_RS09095
uniprot id: A0A223QG77
names: Similarity
names: Subunit
messages: Belongs to the pyruvate kinase family.
messages: Homotetramer.

2014:EL646 RS20970
gene id: 2014:EL646_RS20970
uniprot id: A0A223Q7V9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

2014:EL646 RS09160
gene id: 2014:EL646_RS09160
uniprot id: A0A223QG89
names: Similarity
messages: Belongs to the TrpC family.

2014:EL646 RS01990
gene id: 2014:EL646_RS01990
uniprot id: A0A223QC83
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit F family.
messages: Cell membrane
messages: Membrane

2014:EL646 RS25335
gene id: 2014:EL646_RS25335
uniprot id: A0A223QA10
names: Similarity
messages: Belongs to the GPN-loop GTPase family.

2014:EL646 RS10355
gene id: 2014:EL646_RS10355
uniprot id: A0A223QGJ0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

2014:EL646 RS12955
gene id: 2014:EL646_RS12955
uniprot id: A0A223QI64
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.

2014:EL646 RS08305
gene id: 2014:EL646_RS08305
uniprot id: A0A223QFE0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

2014:EL646 RS10255
gene id: 2014:EL646_RS10255
uniprot id: A0A223QGR7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

2014:EL646 RS22850
gene id: 2014:EL646_RS22850
uniprot id: A0A223Q8G1
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

2014:EL646 RS02905
gene id: 2014:EL646_RS02905
uniprot id: A0A223QD31
names: Similarity
messages: Belongs to the YciI family.

2014:EL646 RS21115
gene id: 2014:EL646_RS21115
uniprot id: A0A223Q7U1
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

2014:EL646 RS25440
gene id: 2014:EL646_RS25440
uniprot id: A0A223QAC9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvC family.
messages: Binds 2 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer which binds Holliday junction (HJ) DNA. The HJ becomes 2-fold symmetrical on binding to RuvC with unstacked arms; it has a different conformation from HJ DNA in complex with RuvA. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair. Endonuclease that resolves HJ intermediates. Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction. The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'. Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange. HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

2014:EL646 RS21060
gene id: 2014:EL646_RS21060
uniprot id: A0A223Q7N2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

2014:EL646 RS15410
gene id: 2014:EL646_RS15410
uniprot id: A0A223QJP2
names: Subcellular Location Annotation
messages: Membrane

2014:EL646 RS20155
gene id: 2014:EL646_RS20155
uniprot id: A0A223Q7B1
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family.
messages: Homopolymer.

2014:EL646 RS02360
gene id: 2014:EL646_RS02360
uniprot id: A0A223QCX0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2014:EL646 RS26155
gene id: 2014:EL646_RS26155
uniprot id: A0A223QA76
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

2014:EL646 RS22450
gene id: 2014:EL646_RS22450
uniprot id: A0A223Q881
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

2014:EL646 RS12830
gene id: 2014:EL646_RS12830
uniprot id: A0A223QI39
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

2014:EL646 RS20980
gene id: 2014:EL646_RS20980
uniprot id: A0A223Q7M4
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

2014:EL646 RS18915
gene id: 2014:EL646_RS18915
uniprot id: A0A223Q6L8
names: Subcellular Location Annotation
messages: Membrane

2014:EL646 RS25375
gene id: 2014:EL646_RS25375
uniprot id: A0A223QA03
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glutaminase PdxT/SNO family.
messages: Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS.
messages: In the presence of PdxS, forms a dodecamer of heterodimers. Only shows activity in the heterodimer.

2014:EL646 RS08325
gene id: 2014:EL646_RS08325
uniprot id: A0A223QFT2
names: Function
names: Similarity
messages: Belongs to the WhiA family.
messages: Involved in cell division and chromosome segregation.

2014:EL646 RS22060
gene id: 2014:EL646_RS22060
uniprot id: A0A223Q836
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

2014:EL646 RS04585
gene id: 2014:EL646_RS04585
uniprot id: A0A223QDM3
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

2014:EL646 RS19140
gene id: 2014:EL646_RS19140
uniprot id: A0A223Q6S3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

2014:EL646 RS25915
gene id: 2014:EL646_RS25915
uniprot id: A0A223QAL5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glutamine synthetase family.
messages: Cytoplasm
messages: Oligomer of 12 subunits arranged in the form of two hexagons.

2014:EL646 RS08080
gene id: 2014:EL646_RS08080
uniprot id: A0A223QFS9
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

2014:EL646 RS21035
gene id: 2014:EL646_RS21035
uniprot id: A0A223Q7M8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

2014:EL646 RS20990
gene id: 2014:EL646_RS20990
uniprot id: A0A223Q7M3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

2014:EL646 RS12700
gene id: 2014:EL646_RS12700
uniprot id: A0A223QIC7
names: Subcellular Location Annotation
messages: Membrane

2014:EL646 RS11925
gene id: 2014:EL646_RS11925
uniprot id: A0A223QHG5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

2014:EL646 RS20590
gene id: 2014:EL646_RS20590
uniprot id: A0A223Q7G6
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

2014:EL646 RS08535
gene id: 2014:EL646_RS08535
uniprot id: A0A223QFX7
names: Similarity
messages: Belongs to the GPN-loop GTPase family.

2014:EL646 RS11110
gene id: 2014:EL646_RS11110
uniprot id: A0A223QH84
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LamB/PxpA family.
messages: Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.
messages: Forms a complex composed of PxpA, PxpB and PxpC.

2014:EL646 RS12940
gene id: 2014:EL646_RS12940
uniprot id: A0A223QI24
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2014:EL646 RS14055
gene id: 2014:EL646_RS14055
uniprot id: A0A223QIK5
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

2014:EL646 RS26685
gene id: 2014:EL646_RS26685
uniprot id: A0A223QAZ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

2014:EL646 RS10260
gene id: 2014:EL646_RS10260
uniprot id: A0A223QGM9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

2014:EL646 RS26080
gene id: 2014:EL646_RS26080
uniprot id: A0A223QAP2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

2014:EL646 RS15040
gene id: 2014:EL646_RS15040
uniprot id: A0A223QJ64
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MurCDEF family. MurT subfamily.
messages: Forms a heterodimer with GatD.
messages: The lipid II isoglutaminyl synthase complex catalyzes the formation of alpha-D-isoglutamine in the cell wall lipid II stem peptide. The MurT subunit catalyzes the ATP-dependent amidation of D-glutamate residue of lipid II, converting it to an isoglutamine residue.

2014:EL646 RS15465
gene id: 2014:EL646_RS15465
uniprot id: A0A223QJP8
names: Similarity
messages: Belongs to the HSP15 family.

2014:EL646 RS23800
gene id: 2014:EL646_RS23800
uniprot id: A0A223Q8X2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BioY family.
messages: Cell membrane

2014:EL646 RS21025
gene id: 2014:EL646_RS21025
uniprot id: A0A223Q7X2
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

2014:EL646 RS17680
gene id: 2014:EL646_RS17680
uniprot id: A0A223QKJ6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

2014:EL646 RS08300
gene id: 2014:EL646_RS08300
uniprot id: A0A223QGA1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase-binding protein RbpA family.
messages: Bind 1 Zn(2+) per subunit.
messages: Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters.
messages: Forms a complex with the RNAP catalytic core and with free principal sigma factors.

2014:EL646 RS26470
gene id: 2014:EL646_RS26470
uniprot id: A0A223QAD5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

2014:EL646 RS24750
gene id: 2014:EL646_RS24750
uniprot id: A0A223Q9U1
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

2014:EL646 RS24685
gene id: 2014:EL646_RS24685
uniprot id: A0A223Q9Z1
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

2014:EL646 RS20875
gene id: 2014:EL646_RS20875
uniprot id: A0A223Q7L3
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

2014:EL646 RS25645
gene id: 2014:EL646_RS25645
uniprot id: A0A223QAF0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
messages: Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).
messages: Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2014:EL646 RS07950
gene id: 2014:EL646_RS07950
uniprot id: A0A223QFK6
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

2014:EL646 RS15630
gene id: 2014:EL646_RS15630
uniprot id: A0A223QJH6
names: Subcellular Location Annotation
messages: Membrane

2014:EL646 RS20315
gene id: 2014:EL646_RS20315
uniprot id: A0A223Q7B5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

2014:EL646 RS06820
gene id: 2014:EL646_RS06820
uniprot id: A0A223QEX8
names: Similarity
messages: Belongs to the catalase family.

2014:EL646 RS21075
gene id: 2014:EL646_RS21075
uniprot id: A0A223Q7X9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

2014:EL646 RS08980
gene id: 2014:EL646_RS08980
uniprot id: A0A223QG57
names: Subcellular Location Annotation
messages: Membrane

2014:EL646 RS13690
gene id: 2014:EL646_RS13690
uniprot id: A0A223QID7
names: Subcellular Location Annotation
messages: Cytoplasm

2014:EL646 RS20610
gene id: 2014:EL646_RS20610
uniprot id: A0A223Q7G2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 23 kDa subunit family.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

2014:EL646 RS11815
gene id: 2014:EL646_RS11815
uniprot id: A0A223QLA5
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

2014:EL646 RS20665
gene id: 2014:EL646_RS20665
uniprot id: A0A223Q7H2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

2014:EL646 RS20975
gene id: 2014:EL646_RS20975
uniprot id: A0A223Q7M2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

2014:EL646 RS18385
gene id: 2014:EL646_RS18385
uniprot id: A0A223Q6D0
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

2014:EL646 RS25285
gene id: 2014:EL646_RS25285
uniprot id: A0A223QA37
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

2014:EL646 RS21710
gene id: 2014:EL646_RS21710
uniprot id: A0A223Q840
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

2014:EL646 RS13425
gene id: 2014:EL646_RS13425
uniprot id: A0A223QIC6
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

2014:EL646 RS08720
gene id: 2014:EL646_RS08720
uniprot id: A0A223QFU3
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.

2014:EL646 RS11695
gene id: 2014:EL646_RS11695
uniprot id: A0A223QHH2
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.

2014:EL646 RS10075
gene id: 2014:EL646_RS10075
uniprot id: A0A223QGN5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

2014:EL646 RS21080
gene id: 2014:EL646_RS21080
uniprot id: A0A223Q7N3
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

2014:EL646 RS22945
gene id: 2014:EL646_RS22945
uniprot id: A0A223Q8I2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

2014:EL646 RS21400
gene id: 2014:EL646_RS21400
uniprot id: A0A223Q829
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

2014:EL646 RS08145
gene id: 2014:EL646_RS08145
uniprot id: A0A223QFA9
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
messages: Carbon 2 of the heme B porphyrin ring is defined according to the Fischer nomenclature.
messages: Cell membrane
messages: Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
messages: Membrane

2014:EL646 RS14420
gene id: 2014:EL646_RS14420
uniprot id: A0A223QIT9
names: Subcellular Location Annotation
messages: Membrane

2014:EL646 RS08035
gene id: 2014:EL646_RS08035
uniprot id: A0A223QFI0
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

2014:EL646 RS17675
gene id: 2014:EL646_RS17675
uniprot id: A0A223QKI4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RnpA family.
messages: Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.
messages: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.

2014:EL646 RS18000
gene id: 2014:EL646_RS18000
uniprot id: A0A223Q647
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CrgA family.
messages: Cell membrane
messages: Involved in cell division.

2014:EL646 RS20845
gene id: 2014:EL646_RS20845
uniprot id: A0A223Q7L9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GDT1 family.
messages: Membrane

2014:EL646 RS01740
gene id: 2014:EL646_RS01740
uniprot id: A0A223QCB4
names: Similarity
messages: Belongs to the peptidase S51 family.

2014:EL646 RS20935
gene id: 2014:EL646_RS20935
uniprot id: A0A223Q7U8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

2014:EL646 RS22460
gene id: 2014:EL646_RS22460
uniprot id: A0A223Q8P1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

2014:EL646 RS26880
gene id: 2014:EL646_RS26880
uniprot id: A0A223QAK6
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

2014:EL646 RS25455
gene id: 2014:EL646_RS25455
uniprot id: A0A223Q9U8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YajC family.
messages: Membrane

2014:EL646 RS04320
gene id: 2014:EL646_RS04320
uniprot id: A0A223QDC3
names: Similarity
messages: Belongs to the pterin-4-alpha-carbinolamine dehydratase family.

2014:EL646 RS19755
gene id: 2014:EL646_RS19755
uniprot id: A0A223Q719
names: Subcellular Location Annotation
messages: Membrane

2014:EL646 RS10135
gene id: 2014:EL646_RS10135
uniprot id: A0A223QGP3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

2014:EL646 RS08625
gene id: 2014:EL646_RS08625
uniprot id: A0A223QFT4
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

2014:EL646 RS24765
gene id: 2014:EL646_RS24765
uniprot id: A0A223Q9X2
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

2014:EL646 RS01510
gene id: 2014:EL646_RS01510
uniprot id: A0A223QBT6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsuA/YedE (TC 9.B.102) family.
messages: Cell inner membrane
messages: Membrane

2014:EL646 RS14365
gene id: 2014:EL646_RS14365
uniprot id: A0A223QIT2
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArgJ family.
messages: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.
messages: Cytoplasm
messages: Heterotetramer of two alpha and two beta chains.
messages: Some bacteria possess a monofunctional ArgJ, i.e., capable of catalyzing only the fifth step of the arginine biosynthetic pathway.

2014:EL646 RS10305
gene id: 2014:EL646_RS10305
uniprot id: A0A223QGS4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

2014:EL646 RS18760
gene id: 2014:EL646_RS18760
uniprot id: A0A223Q6I5
names: Similarity
messages: Belongs to the thioredoxin family.

2014:EL646 RS22880
gene id: 2014:EL646_RS22880
uniprot id: A0A223Q909
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

2014:EL646 RS22195
gene id: 2014:EL646_RS22195
uniprot id: A0A223Q859
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

2014:EL646 RS22385
gene id: 2014:EL646_RS22385
uniprot id: A0A223Q879
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: A probable RNA-binding protein.
messages: Belongs to the KhpA RNA-binding protein family.
messages: Cytoplasm

2014:EL646 RS25775
gene id: 2014:EL646_RS25775
uniprot id: A0A223QAF8
names: Similarity
messages: Belongs to the YggT family.

2014:EL646 RS22885
gene id: 2014:EL646_RS22885
uniprot id: A0A223Q8M8
names: Caution
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

2014:EL646 RS04070
gene id: 2014:EL646_RS04070
uniprot id: A0A223QD91
names: Similarity
messages: Belongs to the UPF0065 (bug) family.

2014:EL646 RS21030
gene id: 2014:EL646_RS21030
uniprot id: A0A223Q7M9
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

2014:EL646 RS17990
gene id: 2014:EL646_RS17990
uniprot id: A0A223Q650
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

2014:EL646 RS10420
gene id: 2014:EL646_RS10420
uniprot id: A0A223QGQ7
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

2014:EL646 RS20915
gene id: 2014:EL646_RS20915
uniprot id: A0A223Q7Q1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

2014:EL646 RS08760
gene id: 2014:EL646_RS08760
uniprot id: A0A223QG09
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

2014:EL646 RS09640
gene id: 2014:EL646_RS09640
uniprot id: A0A223QGH5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SsgA family.
messages: Cell septum

2014:EL646 RS08750
gene id: 2014:EL646_RS08750
uniprot id: A0A223QG02
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

2014:EL646 RS21610
gene id: 2014:EL646_RS21610
uniprot id: A0A223Q888
names: Similarity
messages: Belongs to the NADH dehydrogenase family.