1969:CP983 RS08580
gene id: 1969:CP983_RS08580
uniprot id: A0A7H8T2L1
names: PTM
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Hydantoinase/dihydropyrimidinase family.
messages: Carbamylation allows a single lysine to coordinate two divalent metal cations.

1969:CP983 RS12085
gene id: 1969:CP983_RS12085
uniprot id: A0A7H8T8N3
names: Similarity
messages: Belongs to the WXG100 family.

1969:CP983 RS12790
gene id: 1969:CP983_RS12790
uniprot id: A0A8E3PHT9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

1969:CP983 RS34920
gene id: 1969:CP983_RS34920
uniprot id: A0A7H8THA7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

1969:CP983 RS11415
gene id: 1969:CP983_RS11415
uniprot id: A0A7H8T4B4
names: Subcellular Location Annotation
messages: Cytoplasm

1969:CP983 RS25535
gene id: 1969:CP983_RS25535
uniprot id: A0A7H8TBS7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

1969:CP983 RS17385
gene id: 1969:CP983_RS17385
uniprot id: A0A7H8T8W2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

1969:CP983 RS17400
gene id: 1969:CP983_RS17400
uniprot id: A0A7H8T7H8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

1969:CP983 RS11540
gene id: 1969:CP983_RS11540
uniprot id: A0A7H8T3X6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

1969:CP983 RS13805
gene id: 1969:CP983_RS13805
uniprot id: A0A7H8T5G6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NucS endonuclease family.
messages: Cleaves both 3' and 5' ssDNA extremities of branched DNA structures.
messages: Cytoplasm

1969:CP983 RS13380
gene id: 1969:CP983_RS13380
uniprot id: A0A7H8T583
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1969:CP983 RS27355
gene id: 1969:CP983_RS27355
uniprot id: A0A8E3Q3W7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-to-5' exoribonuclease specific for small oligoribonucleotides.
messages: Belongs to the oligoribonuclease family.
messages: Cytoplasm

1969:CP983 RS17070
gene id: 1969:CP983_RS17070
uniprot id: A0A7H8TBM9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

1969:CP983 RS17420
gene id: 1969:CP983_RS17420
uniprot id: A0A7H8T7G2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

1969:CP983 RS16350
gene id: 1969:CP983_RS16350
uniprot id: A0A7H8TBA7
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1969:CP983 RS32755
gene id: 1969:CP983_RS32755
uniprot id: A0A7H8TFS5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TerC family.
messages: Membrane

1969:CP983 RS31930
gene id: 1969:CP983_RS31930
uniprot id: A0A7H8TFM5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane
messages: Membrane

1969:CP983 RS14660
gene id: 1969:CP983_RS14660
uniprot id: A0A7H8T5Y2
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 zinc ion per subunit.

1969:CP983 RS17220
gene id: 1969:CP983_RS17220
uniprot id: A0A7H8T8S7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

1969:CP983 RS25805
gene id: 1969:CP983_RS25805
uniprot id: A0A7H8TC63
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

1969:CP983 RS27370
gene id: 1969:CP983_RS27370
uniprot id: A0A7H8TCZ2
names: Similarity
messages: Belongs to the universal stress protein A family.

1969:CP983 RS29715
gene id: 1969:CP983_RS29715
uniprot id: A0A7H8TFF1
names: Similarity
messages: Belongs to the universal stress protein A family.

1969:CP983 RS17825
gene id: 1969:CP983_RS17825
uniprot id: A0A7H8T904
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1969:CP983 RS35050
gene id: 1969:CP983_RS35050
uniprot id: A0A7H8THK1
names: Similarity
messages: Belongs to the glutamine synthetase family.

1969:CP983 RS36680
gene id: 1969:CP983_RS36680
uniprot id: A0A7H8TI78
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
messages: Cytoplasm
messages: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.

1969:CP983 RS13755
gene id: 1969:CP983_RS13755
uniprot id: A0A7H8T5F7
names: Similarity
messages: Belongs to the methylmalonyl-CoA epimerase family.

1969:CP983 RS36300
gene id: 1969:CP983_RS36300
uniprot id: A0A7H8THV9
names: Similarity
messages: Belongs to the GPN-loop GTPase family.

1969:CP983 RS17455
gene id: 1969:CP983_RS17455
uniprot id: A0A7H8T7I8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

1969:CP983 RS13900
gene id: 1969:CP983_RS13900
uniprot id: A0A7H8T6V2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Membrane

1969:CP983 RS35635
gene id: 1969:CP983_RS35635
uniprot id: A0A7H8TIL6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PdxS/SNZ family.
messages: Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively.
messages: In the presence of PdxT, forms a dodecamer of heterodimers.

1969:CP983 RS19065
gene id: 1969:CP983_RS19065
uniprot id: A0A7H8T9N5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PPase family.
messages: Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
messages: Cytoplasm
messages: Homohexamer.

1969:CP983 RS17390
gene id: 1969:CP983_RS17390
uniprot id: A0A7H8T7H4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

1969:CP983 RS21675
gene id: 1969:CP983_RS21675
uniprot id: A0A8E3PKH1
names: Similarity
messages: Belongs to the FemABX family.

1969:CP983 RS13750
gene id: 1969:CP983_RS13750
uniprot id: A0A7H8T6S3
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1969:CP983 RS29105
gene id: 1969:CP983_RS29105
uniprot id: A0A7H8TF76
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

1969:CP983 RS35750
gene id: 1969:CP983_RS35750
uniprot id: A0A7H8TNR7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

1969:CP983 RS27380
gene id: 1969:CP983_RS27380
uniprot id: A0A8E3TNJ6
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

1969:CP983 RS27850
gene id: 1969:CP983_RS27850
uniprot id: A0A8E3Q163
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VKOR family.
messages: Membrane

1969:CP983 RS36160
gene id: 1969:CP983_RS36160
uniprot id: A0A7H8TIV6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase-binding protein RbpA family.
messages: Bind 1 Zn(2+) per subunit.
messages: Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters.
messages: Forms a complex with the RNAP catalytic core and with free principal sigma factors.

1969:CP983 RS34865
gene id: 1969:CP983_RS34865
uniprot id: A0A7H8TGU8
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1B family.
messages: Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
messages: Cytoplasm
messages: The 20S proteasome core is composed of 14 alpha and 14 beta subunits that assemble into four stacked heptameric rings, resulting in a barrel-shaped structure. The two inner rings, each composed of seven catalytic beta subunits, are sandwiched by two outer rings, each composed of seven alpha subunits. The catalytic chamber with the active sites is on the inside of the barrel. Has a gated structure, the ends of the cylinder being occluded by the N-termini of the alpha-subunits. Is capped by the proteasome-associated ATPase, ARC.
messages: The formation of the proteasomal ATPase ARC-20S proteasome complex, likely via the docking of the C-termini of ARC into the intersubunit pockets in the alpha-rings, may trigger opening of the gate for substrate entry. Interconversion between the open-gate and close-gate conformations leads to a dynamic regulation of the 20S proteasome proteolysis activity.

1969:CP983 RS17030
gene id: 1969:CP983_RS17030
uniprot id: A0A7H8T8T1
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1969:CP983 RS23250
gene id: 1969:CP983_RS23250
uniprot id: A0A7H8TAM5
names: Function
names: Similarity
messages: Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.

1969:CP983 RS38475
gene id: 1969:CP983_RS38475
uniprot id: A0A7H8TQS2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ETF alpha-subunit/FixB family.
messages: Binds 1 FAD per dimer.
messages: Heterodimer of an alpha and a beta subunit.
messages: The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase).

1969:CP983 RS17415
gene id: 1969:CP983_RS17415
uniprot id: A0A7H8T7V0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

1969:CP983 RS26410
gene id: 1969:CP983_RS26410
uniprot id: A0A7H8TGM3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Homodimer. Forms a membrane-associated complex with FtsX.
messages: Part of the ABC transporter FtsEX involved in cellular division.

1969:CP983 RS09215
gene id: 1969:CP983_RS09215
uniprot id: A0A8E3Q3N5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Membrane

1969:CP983 RS26095
gene id: 1969:CP983_RS26095
uniprot id: A0A7H8TC58
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

1969:CP983 RS17395
gene id: 1969:CP983_RS17395
uniprot id: A0A7H8TBU7
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

1969:CP983 RS12150
gene id: 1969:CP983_RS12150
uniprot id: A0A7H8T8P2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

1969:CP983 RS33075
gene id: 1969:CP983_RS33075
uniprot id: A0A8E3Q8X2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

1969:CP983 RS28525
gene id: 1969:CP983_RS28525
uniprot id: A0A7H8TEY5
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

1969:CP983 RS07560
gene id: 1969:CP983_RS07560
uniprot id: A0A8E3TGF6
names: Similarity
messages: Belongs to the TPP enzyme family.

1969:CP983 RS17365
gene id: 1969:CP983_RS17365
uniprot id: A0A7H8T7U2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

1969:CP983 RS17095
gene id: 1969:CP983_RS17095
uniprot id: A0A7H8T794
names: Similarity
messages: Belongs to the YciI family.

1969:CP983 RS29000
gene id: 1969:CP983_RS29000
uniprot id: A0A8E3TN84
names: Function
names: Similarity
messages: Belongs to the HrcA family.
messages: Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons.

1969:CP983 RS23555
gene id: 1969:CP983_RS23555
uniprot id: A0A7H8TAW3
names: Subcellular Location Annotation
messages: Cytoplasm

1969:CP983 RS17350
gene id: 1969:CP983_RS17350
uniprot id: A0A7H8TRP2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

1969:CP983 RS31745
gene id: 1969:CP983_RS31745
uniprot id: A0A7H8TGH4
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions.
messages: Cytoplasm
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Non-allosteric.

1969:CP983 RS14770
gene id: 1969:CP983_RS14770
uniprot id: A0A7H8T600
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: Nucleus
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

1969:CP983 RS17290
gene id: 1969:CP983_RS17290
uniprot id: A0A7H8T7F5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

1969:CP983 RS17285
gene id: 1969:CP983_RS17285
uniprot id: A0A7H8T8U1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

1969:CP983 RS17535
gene id: 1969:CP983_RS17535
uniprot id: A0A7H8T7W9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.

1969:CP983 RS12925
gene id: 1969:CP983_RS12925
uniprot id: A0A7H8T4S4
names: Similarity
messages: Belongs to the GPN-loop GTPase family.

1969:CP983 RS22485
gene id: 1969:CP983_RS22485
uniprot id: A0A7H8TAH5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PurS family.
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

1969:CP983 RS17470
gene id: 1969:CP983_RS17470
uniprot id: A0A7H8T7W0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

1969:CP983 RS18050
gene id: 1969:CP983_RS18050
uniprot id: A0A7H8TC45
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 20 kDa subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1969:CP983 RS25710
gene id: 1969:CP983_RS25710
uniprot id: A0A7H8TBV5
names: Similarity
messages: Belongs to the transglycosylase family. Rpf subfamily.

1969:CP983 RS17295
gene id: 1969:CP983_RS17295
uniprot id: A0A7H8TBS1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

1969:CP983 RS15210
gene id: 1969:CP983_RS15210
uniprot id: A0A7H8T662
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1969:CP983 RS25755
gene id: 1969:CP983_RS25755
uniprot id: A0A7H8TBV8
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1969:CP983 RS41345
gene id: 1969:CP983_RS41345
uniprot id: A0A7H8TK03
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1969:CP983 RS28955
gene id: 1969:CP983_RS28955
uniprot id: A0A7H8TE20
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

1969:CP983 RS28135
gene id: 1969:CP983_RS28135
uniprot id: A0A7H8TDA1
names: Similarity
messages: Belongs to the truncated hemoglobin family. Group II subfamily.

1969:CP983 RS17340
gene id: 1969:CP983_RS17340
uniprot id: A0A7H8T7G6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

1969:CP983 RS15795
gene id: 1969:CP983_RS15795
uniprot id: A0A8E3QB00
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

1969:CP983 RS17280
gene id: 1969:CP983_RS17280
uniprot id: A0A7H8T7M7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

1969:CP983 RS21695
gene id: 1969:CP983_RS21695
uniprot id: A0A7H8TB26
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein bS6.

1969:CP983 RS19860
gene id: 1969:CP983_RS19860
uniprot id: A0A7H8T8U3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

1969:CP983 RS18915
gene id: 1969:CP983_RS18915
uniprot id: A0A7H8T869
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1969:CP983 RS35520
gene id: 1969:CP983_RS35520
uniprot id: A0A7H8THR9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SsgA family.
messages: Cell septum

1969:CP983 RS26745
gene id: 1969:CP983_RS26745
uniprot id: A0A7H8TCH5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ClpS family.
messages: Binds to the N-terminal domain of the chaperone ClpA.
messages: Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation.

1969:CP983 RS12500
gene id: 1969:CP983_RS12500
uniprot id: A0A7H8T4M1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

1969:CP983 RS19795
gene id: 1969:CP983_RS19795
uniprot id: A0A8E3TJU2
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1969:CP983 RS05195
gene id: 1969:CP983_RS05195
uniprot id: A0A7H8T591
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

1969:CP983 RS08280
gene id: 1969:CP983_RS08280
uniprot id: A0A8E3Q3C5
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphatidylserine decarboxylase family. PSD-A subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
messages: Cell membrane
messages: Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain.

1969:CP983 RS26535
gene id: 1969:CP983_RS26535
uniprot id: A0A7H8TCE1
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

1969:CP983 RS13095
gene id: 1969:CP983_RS13095
uniprot id: A0A7H8T661
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

1969:CP983 RS18805
gene id: 1969:CP983_RS18805
uniprot id: A0A7H8T8C1
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1969:CP983 RS18140
gene id: 1969:CP983_RS18140
uniprot id: A0A7H8T976
names: Subcellular Location Annotation
messages: Cytoplasm

1969:CP983 RS13965
gene id: 1969:CP983_RS13965
uniprot id: A0A7H8T6V9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. Homoserine kinase subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
messages: Cytoplasm

1969:CP983 RS16115
gene id: 1969:CP983_RS16115
uniprot id: A0A7H8T723
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PNP/MTAP phosphorylase family.
messages: Homotrimer.
messages: The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. Cleaves guanosine, inosine, 2'-deoxyguanosine and 2'-deoxyinosine.

1969:CP983 RS37800
gene id: 1969:CP983_RS37800
uniprot id: A0A7H8TJ19
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type B subfamily.
messages: Part of the 50S ribosomal subunit.

1969:CP983 RS34835
gene id: 1969:CP983_RS34835
uniprot id: A0A7H8TL02
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

1969:CP983 RS32875
gene id: 1969:CP983_RS32875
uniprot id: A0A7H8TNN6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1969:CP983 RS18785
gene id: 1969:CP983_RS18785
uniprot id: A0A7H8T8E1
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DisA family.
messages: Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c-di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation; upon encountering a lesion, the DisA focus arrests at the damaged site and halts c-di-AMP synthesis.
messages: Homooctamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Participates in a DNA-damage check-point that is active prior to asymmetric division when DNA is damaged. DisA forms globular foci that rapidly scan along the chromosomes during sporulation, searching for lesions. When a lesion is present, DisA pauses at the lesion site. This triggers a cellular response that culminates in a temporary block in sporulation initiation.

1969:CP983 RS18055
gene id: 1969:CP983_RS18055
uniprot id: A0A7H8T7S2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 3 family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1969:CP983 RS19295
gene id: 1969:CP983_RS19295
uniprot id: A0A7H8T9U4
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

1969:CP983 RS23995
gene id: 1969:CP983_RS23995
uniprot id: A0A7H8TB31
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DtxR/MntR family.
messages: Cytoplasm
messages: Homodimer.

1969:CP983 RS37260
gene id: 1969:CP983_RS37260
uniprot id: A0A7H8TI39
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the urease gamma subunit family.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

1969:CP983 RS14440
gene id: 1969:CP983_RS14440
uniprot id: A0A7H8T5U7
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

1969:CP983 RS26675
gene id: 1969:CP983_RS26675
uniprot id: A0A7H8TDV8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1969:CP983 RS05500
gene id: 1969:CP983_RS05500
uniprot id: A0A7H8T0R5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1969:CP983 RS17500
gene id: 1969:CP983_RS17500
uniprot id: A0A7H8T8X8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1969:CP983 RS37070
gene id: 1969:CP983_RS37070
uniprot id: A0A7H8TI10
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

1969:CP983 RS34185
gene id: 1969:CP983_RS34185
uniprot id: A0A7H8THW6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SepF family.
messages: Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA.
messages: Cytoplasm
messages: Homodimer. Interacts with FtsZ.

1969:CP983 RS40625
gene id: 1969:CP983_RS40625
uniprot id: A0A7H8TJB0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

1969:CP983 RS35905
gene id: 1969:CP983_RS35905
uniprot id: A0A8E3QH64
names: Similarity
messages: Belongs to the SorC transcriptional regulatory family.

1969:CP983 RS12505
gene id: 1969:CP983_RS12505
uniprot id: A0A7H8T4Z8
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by GTP. Inhibited by UTP.
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1969:CP983 RS15380
gene id: 1969:CP983_RS15380
uniprot id: A0A7H8T6J7
names: Similarity
messages: Belongs to the FBPase class 2 family.

1969:CP983 RS17465
gene id: 1969:CP983_RS17465
uniprot id: A0A7H8T7J9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

1969:CP983 RS17520
gene id: 1969:CP983_RS17520
uniprot id: A0A7H8T7K0
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1969:CP983 RS38470
gene id: 1969:CP983_RS38470
uniprot id: A0A7H8TLV8
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta subunit.
messages: The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase).

1969:CP983 RS36395
gene id: 1969:CP983_RS36395
uniprot id: A0A7H8THP4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sbp family.
messages: Cell membrane

1969:CP983 RS35115
gene id: 1969:CP983_RS35115
uniprot id: A0A7H8THL1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

1969:CP983 RS17805
gene id: 1969:CP983_RS17805
uniprot id: A0A7H8T7Z4
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Membrane

1969:CP983 RS17595
gene id: 1969:CP983_RS17595
uniprot id: A0A7H8T7J8
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

1969:CP983 RS12760
gene id: 1969:CP983_RS12760
uniprot id: A0A7H8T612
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

1969:CP983 RS26395
gene id: 1969:CP983_RS26395
uniprot id: A0A7H8TCL8
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF2.
messages: Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.

1969:CP983 RS34895
gene id: 1969:CP983_RS34895
uniprot id: A0A7H8TGW2
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

1969:CP983 RS19045
gene id: 1969:CP983_RS19045
uniprot id: A0A7H8TMX6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm

1969:CP983 RS17325
gene id: 1969:CP983_RS17325
uniprot id: A0A7H8T8V1
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

1969:CP983 RS13815
gene id: 1969:CP983_RS13815
uniprot id: A0A7H8T5F5
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

1969:CP983 RS31775
gene id: 1969:CP983_RS31775
uniprot id: A0A7H8TF88
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterioferritin family.
messages: Homooligomer of 24 subunits, arranged as 12 dimers, that are packed together to form an approximately spherical molecule with a central cavity, in which large amounts of iron can be deposited.
messages: Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex.

1969:CP983 RS17785
gene id: 1969:CP983_RS17785
uniprot id: A0A8E3TJI0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

1969:CP983 RS24040
gene id: 1969:CP983_RS24040
uniprot id: A0A7H8TFH4
names: Function
names: Similarity
messages: Belongs to the PurU family.
messages: Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).

1969:CP983 RS17045
gene id: 1969:CP983_RS17045
uniprot id: A0A7H8T778
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1969:CP983 RS13895
gene id: 1969:CP983_RS13895
uniprot id: A0A7H8T5I1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

1969:CP983 RS31975
gene id: 1969:CP983_RS31975
uniprot id: A0A7H8TFC5
names: Similarity
messages: Belongs to the YggT family.

1969:CP983 RS12555
gene id: 1969:CP983_RS12555
uniprot id: A0A7H8T4N1
names: Similarity
messages: Belongs to the Nudix hydrolase family.

1969:CP983 RS37230
gene id: 1969:CP983_RS37230
uniprot id: A0A7H8TIW6
names: Similarity
messages: Belongs to the peptidase C40 family.

1969:CP983 RS31800
gene id: 1969:CP983_RS31800
uniprot id: A0A8E3QAT0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ThiG family.
messages: Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
messages: Cytoplasm
messages: Homotetramer. Forms heterodimers with either ThiH or ThiS.

1969:CP983 RS17215
gene id: 1969:CP983_RS17215
uniprot id: A0A7H8T7L6
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

1969:CP983 RS41970
gene id: 1969:CP983_RS41970
uniprot id: A0A7H8TLT9
names: Similarity
messages: Belongs to the WXG100 family.

1969:CP983 RS34885
gene id: 1969:CP983_RS34885
uniprot id: A0A7H8THH2
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the Pup ligase/Pup deamidase family. Pup-conjugating enzyme subfamily.
messages: Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine.
messages: The reaction mechanism probably proceeds via the activation of Pup by phosphorylation of its C-terminal glutamate, which is then subject to nucleophilic attack by the substrate lysine, resulting in an isopeptide bond and the release of phosphate as a good leaving group.

1969:CP983 RS28365
gene id: 1969:CP983_RS28365
uniprot id: A0A8E3Q9R5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1969:CP983 RS17275
gene id: 1969:CP983_RS17275
uniprot id: A0A7H8T7C9
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

1969:CP983 RS14465
gene id: 1969:CP983_RS14465
uniprot id: A0A7H8TAA9
names: Activity Regulation
names: Caution
names: Function
names: Similarity
messages: Allosterically activated by N-acetylglucosamine 6-phosphate (GlcNAc6P).
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily.
messages: Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1969:CP983 RS28790
gene id: 1969:CP983_RS28790
uniprot id: A0A7H8TE12
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

1969:CP983 RS12580
gene id: 1969:CP983_RS12580
uniprot id: A0A7H8T631
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

1969:CP983 RS06325
gene id: 1969:CP983_RS06325
uniprot id: A0A7H8T134
names: Similarity
messages: Belongs to the GPN-loop GTPase family.

1969:CP983 RS11465
gene id: 1969:CP983_RS11465
uniprot id: A0A7H8T3W6
names: Similarity
messages: Belongs to the Nudix hydrolase family.

1969:CP983 RS08685
gene id: 1969:CP983_RS08685
uniprot id: A0A7H8T2P2
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

1969:CP983 RS15275
gene id: 1969:CP983_RS15275
uniprot id: A0A8E3Q5N6
names: Similarity
messages: Belongs to the Nudix hydrolase family.

1969:CP983 RS21445
gene id: 1969:CP983_RS21445
uniprot id: A0A7H8T9Q6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CrgA family.
messages: Cell membrane
messages: Involved in cell division.

1969:CP983 RS32850
gene id: 1969:CP983_RS32850
uniprot id: A0A7H8TGB0
names: Function
names: Similarity
messages: Belongs to the WhiA family.
messages: Involved in cell division and chromosome segregation.

1969:CP983 RS31340
gene id: 1969:CP983_RS31340
uniprot id: A0A8E3Q2B8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

1969:CP983 RS19160
gene id: 1969:CP983_RS19160
uniprot id: A0A8E3TIE1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

1969:CP983 RS15070
gene id: 1969:CP983_RS15070
uniprot id: A0A7H8T690
names: Cofactor
names: Function
messages: Binds 1 [3Fe-4S] cluster.
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

1969:CP983 RS19855
gene id: 1969:CP983_RS19855
uniprot id: A0A8E3Q1M8
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

1969:CP983 RS12460
gene id: 1969:CP983_RS12460
uniprot id: A0A7H8T4H7
names: Subcellular Location Annotation
messages: Cytoplasm

1969:CP983 RS12595
gene id: 1969:CP983_RS12595
uniprot id: A0A7H8T4Q0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: A probable RNA-binding protein.
messages: Belongs to the KhpA RNA-binding protein family.
messages: Cytoplasm

1969:CP983 RS30430
gene id: 1969:CP983_RS30430
uniprot id: A0A7H8TFU4
names: Similarity
messages: Belongs to the GPN-loop GTPase family.

1969:CP983 RS28710
gene id: 1969:CP983_RS28710
uniprot id: A0A7H8TDL3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

1969:CP983 RS32860
gene id: 1969:CP983_RS32860
uniprot id: A0A7H8TFT8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
messages: Cytoplasm

1969:CP983 RS17380
gene id: 1969:CP983_RS17380
uniprot id: A0A7H8T7Q0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

1969:CP983 RS17270
gene id: 1969:CP983_RS17270
uniprot id: A0A7H8T7C3
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

1969:CP983 RS34825
gene id: 1969:CP983_RS34825
uniprot id: A0A7H8TI65
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TRM61 family.
messages: Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA.
messages: Homotetramer composed of a dimer of dimers.

1969:CP983 RS31570
gene id: 1969:CP983_RS31570
uniprot id: A0A7H8TGF5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associates with subunits I, II and III to form cytochrome c oxidase.
messages: Belongs to the cytochrome c oxidase bacterial subunit CtaF family.
messages: Cell membrane
messages: Membrane
messages: Part of cytochrome c oxidase, its function is unknown.

1969:CP983 RS26845
gene id: 1969:CP983_RS26845
uniprot id: A0A7H8TCJ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

1969:CP983 RS34010
gene id: 1969:CP983_RS34010
uniprot id: A0A7H8THR6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the AlaDH/PNT family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reductive amination of pyruvate to L-alanine.

1969:CP983 RS21795
gene id: 1969:CP983_RS21795
uniprot id: A0A7H8TB43
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SsgA family.
messages: Cell septum

1969:CP983 RS35655
gene id: 1969:CP983_RS35655
uniprot id: A0A7H8TIM2
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvA family.
messages: Cytoplasm
messages: Has three domains with a flexible linker between the domains II and III and assumes an 'L' shape. Domain III is highly mobile and contacts RuvB.
messages: Homotetramer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

1969:CP983 RS17330
gene id: 1969:CP983_RS17330
uniprot id: A0A7H8T7G4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

1969:CP983 RS33775
gene id: 1969:CP983_RS33775
uniprot id: A0A7H8TGA2
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.

1969:CP983 RS32970
gene id: 1969:CP983_RS32970
uniprot id: A0A7H8TNZ0
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
messages: Carbon 2 of the heme B porphyrin ring is defined according to the Fischer nomenclature.
messages: Cell membrane
messages: Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
messages: Membrane

1969:CP983 RS30125
gene id: 1969:CP983_RS30125
uniprot id: A0A8E3Q1Z5
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

1969:CP983 RS02545
gene id: 1969:CP983_RS02545
uniprot id: A0A8E3TJ72
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

1969:CP983 RS28515
gene id: 1969:CP983_RS28515
uniprot id: A0A7H8TS85
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

1969:CP983 RS26340
gene id: 1969:CP983_RS26340
uniprot id: A0A7H8TCL0
names: Similarity
messages: Belongs to the OsmC/Ohr family.

1969:CP983 RS21555
gene id: 1969:CP983_RS21555
uniprot id: A0A7H8T9S5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

1969:CP983 RS25715
gene id: 1969:CP983_RS25715
uniprot id: A0A8E3TQY3
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

1969:CP983 RS26295
gene id: 1969:CP983_RS26295
uniprot id: A0A8E3TKU6
names: Similarity
messages: Belongs to the peptidase C56 family.

1969:CP983 RS35320
gene id: 1969:CP983_RS35320
uniprot id: A0A7H8TIE0
names: Subcellular Location Annotation
messages: Membrane

1969:CP983 RS26545
gene id: 1969:CP983_RS26545
uniprot id: A0A7H8TCD4
names: Similarity
messages: Belongs to the UPF0301 (AlgH) family.

1969:CP983 RS29560
gene id: 1969:CP983_RS29560
uniprot id: A0A8E3QHG4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1969:CP983 RS19145
gene id: 1969:CP983_RS19145
uniprot id: A0A7H8T8B1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein bS6.

1969:CP983 RS11870
gene id: 1969:CP983_RS11870
uniprot id: A0A7H8T5C3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

1969:CP983 RS32160
gene id: 1969:CP983_RS32160
uniprot id: A0A7H8TFG8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate synthase component I family.
messages: Heterotetramer consisting of two non-identical subunits: a beta subunit (TrpG) and a large alpha subunit (TrpE).
messages: Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia.

1969:CP983 RS12080
gene id: 1969:CP983_RS12080
uniprot id: A0A7H8T480
names: Similarity
messages: Belongs to the WXG100 family.

1969:CP983 RS36050
gene id: 1969:CP983_RS36050
uniprot id: A0A7H8TI81
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRA-PH family.
messages: Cytoplasm

1969:CP983 RS18615
gene id: 1969:CP983_RS18615
uniprot id: A0A7H8T9E0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transcriptional regulatory Rex family.
messages: Cytoplasm
messages: Homodimer.
messages: Modulates transcription in response to changes in cellular NADH/NAD(+) redox state.

1969:CP983 RS29255
gene id: 1969:CP983_RS29255
uniprot id: A0A7H8TDV0
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1969:CP983 RS13945
gene id: 1969:CP983_RS13945
uniprot id: A0A7H8T5G1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

1969:CP983 RS17375
gene id: 1969:CP983_RS17375
uniprot id: A0A7H8T7E9
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

1969:CP983 RS19800
gene id: 1969:CP983_RS19800
uniprot id: A0A7H8T8T0
names: Function
names: Similarity
messages: Belongs to the aspartokinase family.
messages: Catalyzes the phosphorylation of the beta-carboxyl group of aspartic acid with ATP to yield 4-phospho-L-aspartate, which is involved in the branched biosynthetic pathway leading to the biosynthesis of amino acids lysine, threonine, isoleucine and methionine.

1969:CP983 RS12715
gene id: 1969:CP983_RS12715
uniprot id: A0A7H8T4Q5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

1969:CP983 RS33455
gene id: 1969:CP983_RS33455
uniprot id: A0A7H8TG43
names: Function
names: Similarity
messages: Belongs to the ectoine synthase family.
messages: Catalyzes the circularization of gamma-N-acetyl-alpha,gamma-diaminobutyric acid (ADABA) to ectoine (1,4,5,6-tetrahydro-2-methyl-4-pyrimidine carboxylic acid), which is an excellent osmoprotectant.

1969:CP983 RS31765
gene id: 1969:CP983_RS31765
uniprot id: A0A8E3TM52
names: Cofactor
names: Similarity
messages: Belongs to the class-II DAHP synthase family.
messages: Binds 1 divalent cation per subunit. The enzyme is active with manganese, cobalt or cadmium ions.

1969:CP983 RS04855
gene id: 1969:CP983_RS04855
uniprot id: A0A7H8T0V7
names: Subcellular Location Annotation
messages: Membrane

1969:CP983 RS27680
gene id: 1969:CP983_RS27680
uniprot id: A0A7H8TDE9
names: Subcellular Location Annotation
messages: Membrane

1969:CP983 RS35860
gene id: 1969:CP983_RS35860
uniprot id: A0A7H8TLI3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1969:CP983 RS17120
gene id: 1969:CP983_RS17120
uniprot id: A0A8E3PJ16
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

1969:CP983 RS21685
gene id: 1969:CP983_RS21685
uniprot id: A0A7H8TDQ1
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with bS18 to 16S ribosomal RNA.

1969:CP983 RS21245
gene id: 1969:CP983_RS21245
uniprot id: A0A7H8T9A7
names: Similarity
names: Subunit
messages: Belongs to the Bpa family.
messages: Forms a homooligomeric, either hexameric or heptameric, ring-like structure which stacks co-axially with the proteasomal alpha-rings.

1969:CP983 RS28705
gene id: 1969:CP983_RS28705
uniprot id: A0A7H8THX7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

1969:CP983 RS18135
gene id: 1969:CP983_RS18135
uniprot id: A0A8E3Q6M4
names: Function
names: Similarity
messages: Belongs to the MqnA/MqnD family. MqnA subfamily.
messages: Catalyzes the dehydration of chorismate into 3-[(1-carboxyvinyl)oxy]benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2).

1969:CP983 RS30130
gene id: 1969:CP983_RS30130
uniprot id: A0A7H8TEB8
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

1969:CP983 RS17370
gene id: 1969:CP983_RS17370
uniprot id: A0A7H8T7E8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

1969:CP983 RS21700
gene id: 1969:CP983_RS21700
uniprot id: A0A7H8T9J8
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

1969:CP983 RS28275
gene id: 1969:CP983_RS28275
uniprot id: A0A8E3Q7A3
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1969:CP983 RS25205
gene id: 1969:CP983_RS25205
uniprot id: A0A7H8TCX5
names: Similarity
messages: Belongs to the UDPGP type 2 family.

1969:CP983 RS04770
gene id: 1969:CP983_RS04770
uniprot id: A0A7H8T1S6
names: Similarity
messages: Belongs to the universal stress protein A family.

1969:CP983 RS08070
gene id: 1969:CP983_RS08070
uniprot id: A0A7H8T281
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the gas vesicle GvpA family.
messages: Gas vesicle shell
messages: Gas vesicles are hollow, gas filled proteinaceous nanostructures found in some microorganisms. During planktonic growth they allow positioning of the organism at a favorable depth for light or nutrient acquisition. GvpA forms the protein shell.
messages: The gas vesicle shell is 2 nm thick and consists of a single layer of this protein. It forms helical ribs nearly perpendicular to the long axis of the vesicle.

1969:CP983 RS04790
gene id: 1969:CP983_RS04790
uniprot id: A0A7H8T1M0
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1969:CP983 RS22835
gene id: 1969:CP983_RS22835
uniprot id: A0A7H8TBX5
names: Similarity
messages: Belongs to the PhoU family.
messages: Belongs to the UPF0111 family.

1969:CP983 RS43245
gene id: 1969:CP983_RS43245
uniprot id: A0A7H8TKK3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

1969:CP983 RS32880
gene id: 1969:CP983_RS32880
uniprot id: A0A7H8TH62
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase-binding protein RbpA family.
messages: Bind 1 Zn(2+) per subunit.
messages: Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters.
messages: Forms a complex with the RNAP catalytic core and with free principal sigma factors.

1969:CP983 RS23065
gene id: 1969:CP983_RS23065
uniprot id: A0A7H8TAJ5
names: Caution
names: Similarity
messages: Belongs to the nitrobindin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Lacks the conserved His residue that binds heme iron in the nitrobindin family.

1969:CP983 RS11910
gene id: 1969:CP983_RS11910
uniprot id: A0A7H8T8K3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

1969:CP983 RS13180
gene id: 1969:CP983_RS13180
uniprot id: A0A7H8T6F2
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

1969:CP983 RS35640
gene id: 1969:CP983_RS35640
uniprot id: A0A7H8THB1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glutaminase PdxT/SNO family.
messages: Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS.
messages: In the presence of PdxS, forms a dodecamer of heterodimers. Only shows activity in the heterodimer.

1969:CP983 RS12905
gene id: 1969:CP983_RS12905
uniprot id: A0A7H8T4R5
names: Similarity
messages: Belongs to the GPN-loop GTPase family.

1969:CP983 RS23080
gene id: 1969:CP983_RS23080
uniprot id: A0A7H8TC16
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

1969:CP983 RS21540
gene id: 1969:CP983_RS21540
uniprot id: A0A7H8TN57
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

1969:CP983 RS36380
gene id: 1969:CP983_RS36380
uniprot id: A0A7H8THM9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

1969:CP983 RS17405
gene id: 1969:CP983_RS17405
uniprot id: A0A7H8T901
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

1969:CP983 RS35120
gene id: 1969:CP983_RS35120
uniprot id: A0A7H8TIB6
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

1969:CP983 RS20180
gene id: 1969:CP983_RS20180
uniprot id: A0A7H8T8R2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

1969:CP983 RS28550
gene id: 1969:CP983_RS28550
uniprot id: A0A7H8TDW3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

1969:CP983 RS02390
gene id: 1969:CP983_RS02390
uniprot id: A0A7H8SZ64
names: Subcellular Location Annotation
messages: Membrane

1969:CP983 RS35725
gene id: 1969:CP983_RS35725
uniprot id: A0A7H8THJ6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

1969:CP983 RS10395
gene id: 1969:CP983_RS10395
uniprot id: A0A7H8T3K8
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1969:CP983 RS34855
gene id: 1969:CP983_RS34855
uniprot id: A0A7H8TI72
names: Caution
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic ubiquitin-like protein family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Protein modifier that is covalently attached to lysine residues of substrate proteins, thereby targeting them for proteasomal degradation. The tagging system is termed pupylation.
messages: Strongly interacts with the proteasome-associated ATPase ARC through a hydrophobic interface; the interacting region of Pup lies in its C-terminal half. There is one Pup binding site per ARC hexamer ring.
messages: The N-terminal unstructured half of Pup provides a signal required to initiate unfolding and degradation by the proteasome but is not needed for pupylation, while the C-terminal helical half of Pup interacts with ARC to target proteins to the proteasome.

1969:CP983 RS36045
gene id: 1969:CP983_RS36045
uniprot id: A0A8E3QC69
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

1969:CP983 RS30005
gene id: 1969:CP983_RS30005
uniprot id: A0A8E3PUW6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. AraH/RbsC subfamily.
messages: Membrane
messages: Part of the binding-protein-dependent transport system for D-xylose. Probably responsible for the translocation of the substrate across the membrane.

1969:CP983 RS11545
gene id: 1969:CP983_RS11545
uniprot id: A0A7H8T3Y7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S24 family.
messages: Homodimer.
messages: Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.

1969:CP983 RS06390
gene id: 1969:CP983_RS06390
uniprot id: A0A8E3QAF8
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

1969:CP983 RS26255
gene id: 1969:CP983_RS26255
uniprot id: A0A7H8TGJ2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HPF/YfiA ribosome-associated protein family. Long HPF subfamily.
messages: Cytoplasm
messages: Interacts with 100S ribosomes.
messages: Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth.

1969:CP983 RS30965
gene id: 1969:CP983_RS30965
uniprot id: A0A7H8TER4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.