196164:CE RS12750
gene id: 196164:CE_RS12750
uniprot id: Q8FMD3
names: Function
names: Similarity
messages: ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity.
messages: Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily.

196164:CE RS07150
gene id: 196164:CE_RS07150
uniprot id: Q8FPR3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

196164:CE RS00920
gene id: 196164:CE_RS00920
uniprot id: Q8FU86
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanD family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
messages: Cytoplasm
messages: Heterooctamer of four alpha and four beta subunits.
messages: Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus.

196164:CE RS01450
gene id: 196164:CE_RS01450
uniprot id: Q8FTY6
names: Similarity
messages: Belongs to the glycerate kinase type-1 family.

196164:CE RS08140
gene id: 196164:CE_RS08140
uniprot id: Q8FTD5
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP phosphoribosyltransferase family. Long subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Feedback inhibited by histidine.

196164:CE RS01780
gene id: 196164:CE_RS01780
uniprot id: Q8FSS5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

196164:CE RS08630
gene id: 196164:CE_RS08630
uniprot id: Q8FT38
names: Function
names: Similarity
messages: Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily.
messages: Regulates the transcription of the pyrimidine nucleotide (pyr) operon in response to exogenous pyrimidines.

196164:CE RS13795
gene id: 196164:CE_RS13795
uniprot id: Q8FLS0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

196164:CE RS08545
gene id: 196164:CE_RS08545
uniprot id: Q8FT55
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion.
messages: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.
messages: In the C-terminal section; belongs to the HTP reductase family.
messages: In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family.

196164:CE RS12285
gene id: 196164:CE_RS12285
uniprot id: Q8FMM5
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

196164:CE RS09920
gene id: 196164:CE_RS09920
uniprot id: Q8FNZ7
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Ala-129 is present instead of the conserved Asp which is expected to be an active site residue.
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

196164:CE RS08795
gene id: 196164:CE_RS08795
uniprot id: Q8FPL1
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

196164:CE RS05885
gene id: 196164:CE_RS05885
uniprot id: Q8FQF7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

196164:CE RS09460
gene id: 196164:CE_RS09460
uniprot id: Q8FP89
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

196164:CE RS03285
gene id: 196164:CE_RS03285
uniprot id: Q8FRX9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

196164:CE RS11305
gene id: 196164:CE_RS11305
uniprot id: Q8FN65
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

196164:CE RS06495
gene id: 196164:CE_RS06495
uniprot id: Q8FQ42
names: Subcellular Location Annotation
messages: Membrane

196164:CE RS07905
gene id: 196164:CE_RS07905
uniprot id: Q8FTI4
names: Subcellular Location Annotation
messages: Membrane

196164:CE RS10960
gene id: 196164:CE_RS10960
uniprot id: Q8FND7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IPP isomerase type 1 family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium ion binds only when substrate is bound.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP).
messages: Cytoplasm

196164:CE RS07120
gene id: 196164:CE_RS07120
uniprot id: Q8FPS0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dethiobiotin synthetase family.
messages: Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
messages: Cytoplasm
messages: Homodimer.

196164:CE RS00785
gene id: 196164:CE_RS00785
uniprot id: Q8FUB3
names: Subcellular Location Annotation
messages: Membrane

196164:CE RS13995
gene id: 196164:CE_RS13995
uniprot id: Q8FLN0
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily.

196164:CE RS03010
gene id: 196164:CE_RS03010
uniprot id: P59371
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

196164:CE RS10185
gene id: 196164:CE_RS10185
uniprot id: Q8FNU1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

196164:CE RS00260
gene id: 196164:CE_RS00260
uniprot id: Q8FLE6
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

196164:CE RS07850
gene id: 196164:CE_RS07850
uniprot id: Q8FTJ5
names: Function
names: Subcellular Location Annotation
messages: An essential component of the PknG signaling pathway. When unphosphorylated, it inhibits the activity of 2-oxoglutarate dehydrogenase. When phosphorylated it does not inhibit 2-oxoglutarate dehydrogenase (By similarity).
messages: Cytoplasm

196164:CE RS07640
gene id: 196164:CE_RS07640
uniprot id: Q8FTM8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm

196164:CE RS11475
gene id: 196164:CE_RS11475
uniprot id: Q8FN30
names: Similarity
messages: Belongs to the LacAB/RpiB family.

196164:CE RS09630
gene id: 196164:CE_RS09630
uniprot id: Q8FP55
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).
messages: There is also a thiED fusion protein in this bacteria (AC Q8FTH8).

196164:CE RS07775
gene id: 196164:CE_RS07775
uniprot id: Q8FTK7
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

196164:CE RS02415
gene id: 196164:CE_RS02415
uniprot id: Q8FSE7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

196164:CE RS09375
gene id: 196164:CE_RS09375
uniprot id: Q8FPA7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

196164:CE RS14475
gene id: 196164:CE_RS14475
uniprot id: Q8FSV0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

196164:CE RS02625
gene id: 196164:CE_RS02625
uniprot id: Q8FSA7
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

196164:CE RS14390
gene id: 196164:CE_RS14390
uniprot id: Q8FSW8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AzlC family.
messages: Membrane

196164:CE RS08015
gene id: 196164:CE_RS08015
uniprot id: Q8FTG2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CN hydrolase family. Apolipoprotein N-acyltransferase subfamily.
messages: Catalyzes the phospholipid dependent N-acylation of the N-terminal cysteine of apolipoprotein, the last step in lipoprotein maturation.
messages: Cell membrane
messages: Membrane

196164:CE RS03235
gene id: 196164:CE_RS03235
uniprot id: Q8FRZ0
names: Subcellular Location Annotation
messages: Membrane

196164:CE RS12435
gene id: 196164:CE_RS12435
uniprot id: Q8FMJ6
names: Similarity
messages: Belongs to the glycosyltransferase 20 family.

196164:CE RS04925
gene id: 196164:CE_RS04925
uniprot id: Q8FR06
names: Subcellular Location Annotation
messages: Membrane

196164:CE RS00280
gene id: 196164:CE_RS00280
uniprot id: Q8FUL7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

196164:CE RS04905
gene id: 196164:CE_RS04905
uniprot id: Q8FR10
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

196164:CE RS07170
gene id: 196164:CE_RS07170
uniprot id: Q8FPQ9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

196164:CE RS14150
gene id: 196164:CE_RS14150
uniprot id: Q8FLJ8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.

196164:CE RS04980
gene id: 196164:CE_RS04980
uniprot id: Q8FQZ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

196164:CE RS09315
gene id: 196164:CE_RS09315
uniprot id: Q8RQN0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

196164:CE RS07630
gene id: 196164:CE_RS07630
uniprot id: Q8FTN0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ArgR family.
messages: Cytoplasm
messages: Regulates arginine biosynthesis genes.

196164:CE RS12005
gene id: 196164:CE_RS12005
uniprot id: Q8FMS2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.
messages: Homodimer.

196164:CE RS08610
gene id: 196164:CE_RS08610
uniprot id: Q8FT42
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

196164:CE RS02185
gene id: 196164:CE_RS02185
uniprot id: Q8FSJ3
names: Subcellular Location Annotation
messages: Membrane

196164:CE RS08615
gene id: 196164:CE_RS08615
uniprot id: Q8FT41
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

196164:CE RS13665
gene id: 196164:CE_RS13665
uniprot id: Q8FLU8
names: Similarity
messages: Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.

196164:CE RS10835
gene id: 196164:CE_RS10835
uniprot id: Q8FNG1
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

196164:CE RS11205
gene id: 196164:CE_RS11205
uniprot id: Q8FN87
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

196164:CE RS09825
gene id: 196164:CE_RS09825
uniprot id: Q8FP16
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

196164:CE RS00290
gene id: 196164:CE_RS00290
uniprot id: Q8FUL4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

196164:CE RS11970
gene id: 196164:CE_RS11970
uniprot id: Q8FMT0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.
messages: Binds 2 iron ions per subunit.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.
messages: Tetramer of two alpha and two beta subunits.

196164:CE RS09945
gene id: 196164:CE_RS09945
uniprot id: Q8FNZ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

196164:CE RS10075
gene id: 196164:CE_RS10075
uniprot id: Q8FNW3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EamA transporter family.
messages: Membrane

196164:CE RS08855
gene id: 196164:CE_RS08855
uniprot id: Q8FPJ9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PdxS/SNZ family.
messages: Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively.
messages: In the presence of PdxT, forms a dodecamer of heterodimers.

196164:CE RS06595
gene id: 196164:CE_RS06595
uniprot id: Q8FQ22
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

196164:CE RS03605
gene id: 196164:CE_RS03605
uniprot id: Q8FRR3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm
messages: Homodimer.

196164:CE RS05125
gene id: 196164:CE_RS05125
uniprot id: Q8FQW6
names: Subcellular Location Annotation
messages: Membrane

196164:CE RS05890
gene id: 196164:CE_RS05890
uniprot id: Q8FQF6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type 2 tetrahydrodipicolinate N-succinyltransferase family.
messages: Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2-amino-6-oxopimelate using succinyl-CoA.
messages: Cytoplasm
messages: Homotrimer.

196164:CE RS02555
gene id: 196164:CE_RS02555
uniprot id: Q8FSB8
names: Similarity
messages: Belongs to the pterin-4-alpha-carbinolamine dehydratase family.

196164:CE RS03020
gene id: 196164:CE_RS03020
uniprot id: Q8FS33
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

196164:CE RS14470
gene id: 196164:CE_RS14470
uniprot id: Q8FSV1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Specifically methylates the N7 position of guanine in position 518 of 16S rRNA.

196164:CE RS13480
gene id: 196164:CE_RS13480
uniprot id: Q8FLY5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.

196164:CE RS03350
gene id: 196164:CE_RS03350
uniprot id: Q8FRW6
names: Subcellular Location Annotation
messages: Membrane

196164:CE RS09420
gene id: 196164:CE_RS09420
uniprot id: Q8FP97
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.
messages: Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.
messages: Cytoplasm
messages: Homodimer.

196164:CE RS03075
gene id: 196164:CE_RS03075
uniprot id: Q8FS24
names: Similarity
messages: Belongs to the WXG100 family.

196164:CE RS09745
gene id: 196164:CE_RS09745
uniprot id: Q8FP30
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

196164:CE RS02110
gene id: 196164:CE_RS02110
uniprot id: Q8FSK9
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

196164:CE RS09280
gene id: 196164:CE_RS09280
uniprot id: Q8FPC4
names: Similarity
messages: Belongs to the YciI family.

196164:CE RS00435
gene id: 196164:CE_RS00435
uniprot id: Q8FUI7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CrgA family.
messages: Cell membrane
messages: Involved in cell division.

196164:CE RS04800
gene id: 196164:CE_RS04800
uniprot id: Q8FR29
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

196164:CE RS05720
gene id: 196164:CE_RS05720
uniprot id: Q8FQJ4
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

196164:CE RS05935
gene id: 196164:CE_RS05935
uniprot id: Q8FQE6
names: Similarity
messages: Belongs to the glycosyl hydrolase 32 family.

196164:CE RS11755
gene id: 196164:CE_RS11755
uniprot id: Q8FMX4
names: Similarity
names: Subunit
messages: Belongs to the glutaminase family.
messages: Homotetramer.

196164:CE RS07100
gene id: 196164:CE_RS07100
uniprot id: Q8FPS4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Nitrate/nitrite porter (TC 2.A.1.8) family.
messages: Membrane

196164:CE RS13010
gene id: 196164:CE_RS13010
uniprot id: Q8FM79
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

196164:CE RS03120
gene id: 196164:CE_RS03120
uniprot id: Q8FS13
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

196164:CE RS11280
gene id: 196164:CE_RS11280
uniprot id: Q8FN70
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

196164:CE RS10540
gene id: 196164:CE_RS10540
uniprot id: Q8FNL8
names: Function
names: Similarity
messages: Belongs to the GlnE family.
messages: Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell.

196164:CE RS09950
gene id: 196164:CE_RS09950
uniprot id: Q8FNZ1
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

196164:CE RS04850
gene id: 196164:CE_RS04850
uniprot id: Q8FR21
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type B subfamily.
messages: Part of the 50S ribosomal subunit.

196164:CE RS02215
gene id: 196164:CE_RS02215
uniprot id: Q8FSI7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Bcr/CmlA family.
messages: Membrane

196164:CE RS03290
gene id: 196164:CE_RS03290
uniprot id: Q8FRX8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. Methionine importer (TC 3.A.1.24) family.
messages: Cell membrane
messages: Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system.
messages: The complex is composed of two ATP-binding proteins (MetN), two transmembrane proteins (MetI) and a solute-binding protein (MetQ).

196164:CE RS03700
gene id: 196164:CE_RS03700
uniprot id: Q8FRP3
names: Similarity
messages: Belongs to the PrpD family.

196164:CE RS10780
gene id: 196164:CE_RS10780
uniprot id: Q8FNH2
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

196164:CE RS01400
gene id: 196164:CE_RS01400
uniprot id: Q8FTZ6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

196164:CE RS09300
gene id: 196164:CE_RS09300
uniprot id: Q8FPB9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily.
messages: Cytoplasm
messages: Homodimer, may be a subunit of the RNA degradosome.

196164:CE RS04175
gene id: 196164:CE_RS04175
uniprot id: Q8FRE9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Homodimer. Forms a membrane-associated complex with FtsX.
messages: Part of the ABC transporter FtsEX involved in cellular division.

196164:CE RS03295
gene id: 196164:CE_RS03295
uniprot id: Q8FRX7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NlpA lipoprotein family.
messages: Membrane

196164:CE RS10035
gene id: 196164:CE_RS10035
uniprot id: Q8FNX1
names: Similarity
messages: Belongs to the HSP15 family.

196164:CE RS12220
gene id: 196164:CE_RS12220
uniprot id: Q8FMN8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

196164:CE RS01415
gene id: 196164:CE_RS01415
uniprot id: Q8FTZ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit E family.
messages: Cell membrane
messages: Membrane

196164:CE RS13110
gene id: 196164:CE_RS13110
uniprot id: Q8FM59
names: Similarity
messages: Belongs to the flavin oxidoreductase frp family.

196164:CE RS09340
gene id: 196164:CE_RS09340
uniprot id: Q8FPB4
names: Similarity
messages: Belongs to the ribF family.

196164:CE RS02140
gene id: 196164:CE_RS02140
uniprot id: Q8FSK2
names: Cofactor
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Binds 1 [3Fe-4S] cluster.
messages: Binds 1 [4Fe-4S] cluster.

196164:CE RS01325
gene id: 196164:CE_RS01325
uniprot id: Q8FU11
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

196164:CE RS09175
gene id: 196164:CE_RS09175
uniprot id: Q8FPE1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.

196164:CE RS13355
gene id: 196164:CE_RS13355
uniprot id: Q8FM09
names: Subcellular Location Annotation
messages: Membrane

196164:CE RS02810
gene id: 196164:CE_RS02810
uniprot id: Q8FS74
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

196164:CE RS06700
gene id: 196164:CE_RS06700
uniprot id: Q8FQ01
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm

196164:CE RS02805
gene id: 196164:CE_RS02805
uniprot id: Q8FS75
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

196164:CE RS10390
gene id: 196164:CE_RS10390
uniprot id: Q8FNQ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobS family.
messages: Cell membrane
messages: Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.

196164:CE RS08320
gene id: 196164:CE_RS08320
uniprot id: Q8FTA1
names: Similarity
names: Subunit
messages: Belongs to the UPF0210 family.
messages: Homodimer.

196164:CE RS06020
gene id: 196164:CE_RS06020
uniprot id: Q8FQD0
names: Subcellular Location Annotation
messages: Membrane

196164:CE RS01195
gene id: 196164:CE_RS01195
uniprot id: Q8FU32
names: Similarity
messages: Belongs to the bacterial solute-binding protein ModA family.

196164:CE RS13315
gene id: 196164:CE_RS13315
uniprot id: Q8FM18
names: Subcellular Location Annotation
messages: Membrane

196164:CE RS01280
gene id: 196164:CE_RS01280
uniprot id: Q8FU19
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily.
messages: Cell membrane
messages: Involved in the import of queuosine (Q) precursors, required for Q precursor salvage.

196164:CE RS02835
gene id: 196164:CE_RS02835
uniprot id: Q8FS69
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

196164:CE RS08165
gene id: 196164:CE_RS08165
uniprot id: Q8FTD0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MshC subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the ATP-dependent condensation of GlcN-Ins and L-cysteine to form L-Cys-GlcN-Ins.
messages: Monomer.

196164:CE RS00035
gene id: 196164:CE_RS00035
uniprot id: Q8FLI9
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

196164:CE RS11250
gene id: 196164:CE_RS11250
uniprot id: Q8FN77
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

196164:CE RS14195
gene id: 196164:CE_RS14195
uniprot id: Q8FT12
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

196164:CE RS11720
gene id: 196164:CE_RS11720
uniprot id: Q8FMX9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-to-5' exoribonuclease specific for small oligoribonucleotides.
messages: Belongs to the oligoribonuclease family.
messages: Cytoplasm

196164:CE RS09235
gene id: 196164:CE_RS09235
uniprot id: Q8FPD3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

196164:CE RS11385
gene id: 196164:CE_RS11385
uniprot id: Q8FN49
names: Similarity
messages: Belongs to the class-II fumarase/aspartase family.

196164:CE RS09530
gene id: 196164:CE_RS09530
uniprot id: Q8FP75
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

196164:CE RS06830
gene id: 196164:CE_RS06830
uniprot id: Q8FPX7
names: Subcellular Location Annotation
messages: Membrane

196164:CE RS09905
gene id: 196164:CE_RS09905
uniprot id: Q8FP00
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PRA-CH family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.
messages: Cytoplasm
messages: Homodimer.

196164:CE RS06310
gene id: 196164:CE_RS06310
uniprot id: Q8FQ76
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the arginase family.
messages: Binds 2 manganese ions per subunit.
messages: Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide.

196164:CE RS13380
gene id: 196164:CE_RS13380
uniprot id: Q8FM05
names: Similarity
messages: Belongs to the AccD/PCCB family.

196164:CE RS05225
gene id: 196164:CE_RS05225
uniprot id: Q8FQU4
names: Subcellular Location Annotation
messages: Membrane

196164:CE RS13230
gene id: 196164:CE_RS13230
uniprot id: Q8FM36
names: Similarity
messages: Belongs to the universal stress protein A family.

196164:CE RS11230
gene id: 196164:CE_RS11230
uniprot id: Q8FN81
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

196164:CE RS09755
gene id: 196164:CE_RS09755
uniprot id: Q8FP28
names: Subcellular Location Annotation
messages: Membrane

196164:CE RS03610
gene id: 196164:CE_RS03610
uniprot id: Q8FRR2
names: Subcellular Location Annotation
messages: Membrane

196164:CE RS10905
gene id: 196164:CE_RS10905
uniprot id: Q8FNE7
names: Subcellular Location Annotation
messages: Membrane

196164:CE RS14305
gene id: 196164:CE_RS14305
uniprot id: Q8FSY8
names: Subcellular Location Annotation
messages: Cytoplasm

196164:CE RS14245
gene id: 196164:CE_RS14245
uniprot id: Q8FT01
names: Subcellular Location Annotation
messages: Membrane

196164:CE RS09155
gene id: 196164:CE_RS09155
uniprot id: Q8FPE6
names: Subcellular Location Annotation
messages: Membrane

196164:CE RS00840
gene id: 196164:CE_RS00840
uniprot id: Q8FUA2
names: Similarity
messages: Belongs to the DNA glycosylase MPG family.

196164:CE RS03525
gene id: 196164:CE_RS03525
uniprot id: Q8FRT0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AB hydrolase superfamily. MetX family.
messages: Cytoplasm
messages: Homodimer.
messages: Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.

196164:CE RS09390
gene id: 196164:CE_RS09390
uniprot id: Q8FPA4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

196164:CE RS04025
gene id: 196164:CE_RS04025
uniprot id: Q8FRH8
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

196164:CE RS04710
gene id: 196164:CE_RS04710
uniprot id: Q8FR47
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

196164:CE RS10380
gene id: 196164:CE_RS10380
uniprot id: Q8FNQ3
names: Function
names: Similarity
messages: Belongs to the CobU/CobP family.
messages: Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate.

196164:CE RS12860
gene id: 196164:CE_RS12860
uniprot id: Q8FMB0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

196164:CE RS08250
gene id: 196164:CE_RS08250
uniprot id: Q8FTB5
names: Similarity
messages: Belongs to the band 7/mec-2 family.

196164:CE RS04820
gene id: 196164:CE_RS04820
uniprot id: P66456
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein bS6.

196164:CE RS03125
gene id: 196164:CE_RS03125
uniprot id: Q8FS12
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaD and TsaB. TsaE seems to play an indirect role in the t(6)A biosynthesis pathway, possibly in regulating the core enzymatic function of TsaD.

196164:CE RS09845
gene id: 196164:CE_RS09845
uniprot id: Q8FP11
names: Subcellular Location Annotation
messages: Membrane

196164:CE RS01340
gene id: 196164:CE_RS01340
uniprot id: Q8FU08
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MurCDEF family. MurT subfamily.
messages: Forms a heterodimer with GatD.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The lipid II isoglutaminyl synthase complex catalyzes the formation of alpha-D-isoglutamine in the cell wall lipid II stem peptide. The MurT subunit catalyzes the ATP-dependent amidation of D-glutamate residue of lipid II, converting it to an isoglutamine residue.

196164:CE RS08625
gene id: 196164:CE_RS08625
uniprot id: Q8FT39
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

196164:CE RS01685
gene id: 196164:CE_RS01685
uniprot id: Q8FSU2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

196164:CE RS06930
gene id: 196164:CE_RS06930
uniprot id: Q8FPV5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 2 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.

196164:CE RS09805
gene id: 196164:CE_RS09805
uniprot id: Q7ZAJ9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.

196164:CE RS05490
gene id: 196164:CE_RS05490
uniprot id: Q8FQP1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseA family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

196164:CE RS01255
gene id: 196164:CE_RS01255
uniprot id: Q8FU23
names: Similarity
messages: Belongs to the UPF0337 (CsbD) family.

196164:CE RS13345
gene id: 196164:CE_RS13345
uniprot id: Q8FM11
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.

196164:CE RS04825
gene id: 196164:CE_RS04825
uniprot id: Q8FR26
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

196164:CE RS02475
gene id: 196164:CE_RS02475
uniprot id: Q8FSD4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

196164:CE RS02445
gene id: 196164:CE_RS02445
uniprot id: Q8FSE1
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Homooctamer.

196164:CE RS02650
gene id: 196164:CE_RS02650
uniprot id: Q8FSA1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

196164:CE RS08765
gene id: 196164:CE_RS08765
uniprot id: Q8CM29
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

196164:CE RS08475
gene id: 196164:CE_RS08475
uniprot id: Q8FT69
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

196164:CE RS03330
gene id: 196164:CE_RS03330
uniprot id: Q8FRX0
names: Subcellular Location Annotation
messages: Membrane

196164:CE RS09060
gene id: 196164:CE_RS09060
uniprot id: Q8FPG5
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

196164:CE RS01330
gene id: 196164:CE_RS01330
uniprot id: Q8FU10
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

196164:CE RS03740
gene id: 196164:CE_RS03740
uniprot id: Q8CWF0
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

196164:CE RS07965
gene id: 196164:CE_RS07965
uniprot id: Q8FTH1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MntP (TC 9.B.29) family.
messages: Cell membrane
messages: Probably functions as a manganese efflux pump.

196164:CE RS12620
gene id: 196164:CE_RS12620
uniprot id: Q8FMG0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Cytoplasm
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
messages: The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.

196164:CE RS09730
gene id: 196164:CE_RS09730
uniprot id: Q8FP33
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein uS19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein uS19.

196164:CE RS01825
gene id: 196164:CE_RS01825
uniprot id: Q8FSR7
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

196164:CE RS01075
gene id: 196164:CE_RS01075
uniprot id: Q8FU55
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

196164:CE RS12000
gene id: 196164:CE_RS12000
uniprot id: P61174
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

196164:CE RS06910
gene id: 196164:CE_RS06910
uniprot id: Q8FPV9
names: Function
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

196164:CE RS09595
gene id: 196164:CE_RS09595
uniprot id: Q8FP62
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Membrane

196164:CE RS07785
gene id: 196164:CE_RS07785
uniprot id: Q8FTK5
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

196164:CE RS06260
gene id: 196164:CE_RS06260
uniprot id: Q8FQ88
names: Similarity
messages: Belongs to the IS21/IS1162 putative ATP-binding protein family.

196164:CE RS06100
gene id: 196164:CE_RS06100
uniprot id: Q8FQB3
names: Subcellular Location Annotation
messages: Membrane

196164:CE RS14165
gene id: 196164:CE_RS14165
uniprot id: Q8FLJ5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

196164:CE RS11045
gene id: 196164:CE_RS11045
uniprot id: Q8FNB9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

196164:CE RS06365
gene id: 196164:CE_RS06365
uniprot id: Q8FQ65
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit A family.

196164:CE RS00905
gene id: 196164:CE_RS00905
uniprot id: Q8FU89
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

196164:CE RS08775
gene id: 196164:CE_RS08775
uniprot id: Q8FPL5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

196164:CE RS07635
gene id: 196164:CE_RS07635
uniprot id: Q8FTM9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.

196164:CE RS12730
gene id: 196164:CE_RS12730
uniprot id: Q8FMD7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit E family.
messages: Cell membrane
messages: Membrane

196164:CE RS05665
gene id: 196164:CE_RS05665
uniprot id: Q8FQK6
names: Similarity
messages: Belongs to the YjdM family.

196164:CE RS12535
gene id: 196164:CE_RS12535
uniprot id: Q8FMH7
names: Function
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.
messages: Catalyzes the reversible hydration of carbon dioxide to form bicarbonate.
messages: Reversible hydration of carbon dioxide.

196164:CE RS14310
gene id: 196164:CE_RS14310
uniprot id: Q8FSY7
names: Subcellular Location Annotation
messages: Membrane

196164:CE RS02825
gene id: 196164:CE_RS02825
uniprot id: Q8FS71
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

196164:CE RS10355
gene id: 196164:CE_RS10355
uniprot id: Q8FNQ8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associates with subunits I, II and III to form cytochrome c oxidase.
messages: Belongs to the cytochrome c oxidase bacterial subunit CtaF family.
messages: Cell membrane
messages: Part of cytochrome c oxidase, its function is unknown.

196164:CE RS11680
gene id: 196164:CE_RS11680
uniprot id: Q8FMY8
names: Function
names: Similarity
messages: Belongs to the LarC family.
messages: Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2+), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor-dependent enzymes.

196164:CE RS10900
gene id: 196164:CE_RS10900
uniprot id: Q8FNE8
names: Similarity
messages: Belongs to the disproportionating enzyme family.

196164:CE RS09135
gene id: 196164:CE_RS09135
uniprot id: Q8FPF0
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.

196164:CE RS10425
gene id: 196164:CE_RS10425
uniprot id: Q8FNP4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

196164:CE RS02800
gene id: 196164:CE_RS02800
uniprot id: P59181
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

196164:CE RS06835
gene id: 196164:CE_RS06835
uniprot id: Q8FPX6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.

196164:CE RS00520
gene id: 196164:CE_RS00520
uniprot id: Q8FUH0
names: Similarity
messages: Belongs to the HsdR family.

196164:CE RS07005
gene id: 196164:CE_RS07005
uniprot id: Q8FPU0
names: Subcellular Location Annotation
messages: Membrane

196164:CE RS11115
gene id: 196164:CE_RS11115
uniprot id: Q8FNA5
names: Subcellular Location Annotation
messages: Membrane

196164:CE RS01860
gene id: 196164:CE_RS01860
uniprot id: Q8FSR0
names: Function
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.
messages: Could possibly oxidize fatty acids using specific components.

196164:CE RS10260
gene id: 196164:CE_RS10260
uniprot id: Q8FNS6
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

196164:CE RS05015
gene id: 196164:CE_RS05015
uniprot id: Q8FQY8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the polyphosphate kinase 2 (PPK2) family. Class I subfamily.
messages: Homotetramer.
messages: Uses inorganic polyphosphate (polyP) as a donor to convert GDP to GTP or ADP to ATP.

196164:CE RS03495
gene id: 196164:CE_RS03495
uniprot id: Q8FRT6
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

196164:CE RS00565
gene id: 196164:CE_RS00565
uniprot id: Q8FUF9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

196164:CE RS11125
gene id: 196164:CE_RS11125
uniprot id: Q8FNA3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

196164:CE RS03095
gene id: 196164:CE_RS03095
uniprot id: Q8FS19
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

196164:CE RS06480
gene id: 196164:CE_RS06480
uniprot id: Q8FQ44
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. Homoserine kinase subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
messages: Cytoplasm

196164:CE RS11135
gene id: 196164:CE_RS11135
uniprot id: Q8FNA1
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

196164:CE RS06585
gene id: 196164:CE_RS06585
uniprot id: Q8FQ24
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.

196164:CE RS10165
gene id: 196164:CE_RS10165
uniprot id: Q8FNU5
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

196164:CE RS01610
gene id: 196164:CE_RS01610
uniprot id: Q8FTV6
names: Similarity
names: Subunit
messages: Belongs to the multicopper oxidase family.
messages: Homotrimer.

196164:CE RS06650
gene id: 196164:CE_RS06650
uniprot id: Q8FQ11
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 13 family. GlgE subfamily.
messages: Homodimer.
messages: Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1->4)-glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB.

196164:CE RS12845
gene id: 196164:CE_RS12845
uniprot id: Q8FMB3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Homodimer.
messages: Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate.

196164:CE RS06675
gene id: 196164:CE_RS06675
uniprot id: Q8FQ06
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ETF alpha-subunit/FixB family.
messages: Binds 1 FAD per dimer.
messages: Heterodimer of an alpha and a beta subunit.
messages: The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase).

196164:CE RS10860
gene id: 196164:CE_RS10860
uniprot id: Q8FNF6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

196164:CE RS01465
gene id: 196164:CE_RS01465
uniprot id: Q8CM46
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

196164:CE RS10140
gene id: 196164:CE_RS10140
uniprot id: Q8FNV0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

196164:CE RS08700
gene id: 196164:CE_RS08700
uniprot id: Q8FT24
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF nuclease family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

196164:CE RS11825
gene id: 196164:CE_RS11825
uniprot id: Q8FMV9
names: Subcellular Location Annotation
messages: Membrane

196164:CE RS12095
gene id: 196164:CE_RS12095
uniprot id: Q8FMQ9
names: Similarity
messages: Belongs to the Cob(I)alamin adenosyltransferase family.

196164:CE RS12825
gene id: 196164:CE_RS12825
uniprot id: Q8FMB7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Mg(2+). Can also accept Mn(2+).

196164:CE RS01080
gene id: 196164:CE_RS01080
uniprot id: Q8FU54
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

196164:CE RS02795
gene id: 196164:CE_RS02795
uniprot id: Q8FS76
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity).

196164:CE RS03800
gene id: 196164:CE_RS03800
uniprot id: Q8FRM5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family.
messages: Cytoplasm
messages: Nucleoside triphosphate pyrophosphatase. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

196164:CE RS02765
gene id: 196164:CE_RS02765
uniprot id: P66327
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

196164:CE RS12880
gene id: 196164:CE_RS12880
uniprot id: Q8FMA6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class II fructose-bisphosphate aldolase family.
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.
messages: Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.

196164:CE RS13500
gene id: 196164:CE_RS13500
uniprot id: Q8FLY1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsuA/YedE (TC 9.B.102) family.
messages: Belongs to the sulfur carrier protein TusA family.
messages: Cell inner membrane
messages: Membrane

196164:CE RS12305
gene id: 196164:CE_RS12305
uniprot id: Q8FMM1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PurS family.
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

196164:CE RS10340
gene id: 196164:CE_RS10340
uniprot id: Q8FNR1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Rieske iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: Cell membrane
messages: Iron-sulfur subunit of the cytochrome bc1 complex, an essential component of the respiratory electron transport chain required for ATP synthesis. The bc1 complex catalyzes the oxidation of menaquinol and the reduction of cytochrome c in the respiratory chain. The bc1 complex operates through a Q-cycle mechanism that couples electron transfer to generation of the proton gradient that drives ATP synthesis.
messages: The cytochrome bc1 complex is composed of a cytochrome b (QcrB), the Rieske iron-sulfur protein (QcrA) and a diheme cytochrome c (QcrC) subunit. The bc1 complex forms a supercomplex with cytochrome c oxidase (cytochrome aa3).

196164:CE RS13905
gene id: 196164:CE_RS13905
uniprot id: Q8FLP9
names: Subunit
messages: Homotetramer.

196164:CE RS03570
gene id: 196164:CE_RS03570
uniprot id: Q8FRS1
names: Subcellular Location Annotation
messages: Membrane

196164:CE RS08810
gene id: 196164:CE_RS08810
uniprot id: Q8FPK8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

196164:CE RS05105
gene id: 196164:CE_RS05105
uniprot id: Q8FQX0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UreF family.
messages: Cytoplasm
messages: Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
messages: UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

196164:CE RS02565
gene id: 196164:CE_RS02565
uniprot id: Q8FSB6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TPP enzyme family. MenD subfamily.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC).
messages: Homodimer.

196164:CE RS09120
gene id: 196164:CE_RS09120
uniprot id: Q8FPF3
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.

196164:CE RS11880
gene id: 196164:CE_RS11880
uniprot id: Q8FMU9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

196164:CE RS09780
gene id: 196164:CE_RS09780
uniprot id: Q8FP24
names: Similarity
messages: Belongs to the P(II) protein family.

196164:CE RS03835
gene id: 196164:CE_RS03835
uniprot id: Q8FRL7
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

196164:CE RS12630
gene id: 196164:CE_RS12630
uniprot id: Q8FMF8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PPase family.
messages: Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
messages: Cytoplasm
messages: Homohexamer.

196164:CE RS12060
gene id: 196164:CE_RS12060
uniprot id: Q8FMR4
names: Subcellular Location Annotation
messages: Membrane

196164:CE RS10645
gene id: 196164:CE_RS10645
uniprot id: Q8FNJ9
names: Subcellular Location Annotation
messages: Membrane

196164:CE RS05400
gene id: 196164:CE_RS05400
uniprot id: Q8FQR0
names: Similarity
messages: In the C-terminal section; belongs to the anthranilate synthase component I family.

196164:CE RS11025
gene id: 196164:CE_RS11025
uniprot id: Q8FNC3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

196164:CE RS09770
gene id: 196164:CE_RS09770
uniprot id: Q8FP25
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

196164:CE RS10825
gene id: 196164:CE_RS10825
uniprot id: Q8FNG3
names: Subcellular Location Annotation
messages: Membrane

196164:CE RS04770
gene id: 196164:CE_RS04770
uniprot id: Q8FR35
names: Subcellular Location Annotation
messages: Membrane

196164:CE RS09055
gene id: 196164:CE_RS09055
uniprot id: Q8FPG6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DtxR/MntR family.
messages: Cytoplasm
messages: Homodimer.
messages: Iron-binding repressor of the dipheteria toxin gene expression. May serve as a global regulator of gene expression. Represses ripA under iron excess (By similarity).

196164:CE RS07735
gene id: 196164:CE_RS07735
uniprot id: Q8FTL2
names: Activity Regulation
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.

196164:CE RS12500
gene id: 196164:CE_RS12500
uniprot id: Q8FMI3
names: Function
names: Similarity
messages: Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).

196164:CE RS09515
gene id: 196164:CE_RS09515
uniprot id: Q8FP78
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.

196164:CE RS03165
gene id: 196164:CE_RS03165
uniprot id: Q8CY27
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

196164:CE RS09260
gene id: 196164:CE_RS09260
uniprot id: Q8FPC8
names: Similarity
messages: Belongs to the PspA/IM30 family.

196164:CE RS08400
gene id: 196164:CE_RS08400
uniprot id: Q8FT84
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

196164:CE RS12270
gene id: 196164:CE_RS12270
uniprot id: Q8FMM8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

196164:CE RS03435
gene id: 196164:CE_RS03435
uniprot id: Q8FRU9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

196164:CE RS11430
gene id: 196164:CE_RS11430
uniprot id: Q8FN40
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

196164:CE RS06105
gene id: 196164:CE_RS06105
uniprot id: Q8FQB2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 independent methionine synthase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine resulting in methionine formation.

196164:CE RS05235
gene id: 196164:CE_RS05235
uniprot id: Q8CM46
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

196164:CE RS03950
gene id: 196164:CE_RS03950
uniprot id: Q8FRJ3
names: Caution
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

196164:CE RS02470
gene id: 196164:CE_RS02470
uniprot id: Q8FSD5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protoporphyrinogen/coproporphyrinogen oxidase family. Coproporphyrinogen III oxidase subfamily.
messages: Cytoplasm
messages: Involved in coproporphyrin-dependent heme b biosynthesis. Catalyzes the oxidation of coproporphyrinogen III to coproporphyrin III.

196164:CE RS00235
gene id: 196164:CE_RS00235
uniprot id: Q8FLF1
names: Similarity
messages: Belongs to the site-specific recombinase resolvase family.

196164:CE RS10495
gene id: 196164:CE_RS10495
uniprot id: Q8FNM8
names: Similarity
messages: Belongs to the glutamine synthetase family.

196164:CE RS11390
gene id: 196164:CE_RS11390
uniprot id: Q8FN48
names: Similarity
messages: Belongs to the intradiol ring-cleavage dioxygenase family.

196164:CE RS08230
gene id: 196164:CE_RS08230
uniprot id: Q8FTB9
names: Subunit
messages: Heterodimer of an alpha and a beta chain.

196164:CE RS11235
gene id: 196164:CE_RS11235
uniprot id: Q8FN80
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

196164:CE RS07050
gene id: 196164:CE_RS07050
uniprot id: Q8FPT3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ThiC family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

196164:CE RS02120
gene id: 196164:CE_RS02120
uniprot id: Q8FSK6
names: Similarity
messages: Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily.

196164:CE RS02590
gene id: 196164:CE_RS02590
uniprot id: Q8FSB1
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

196164:CE RS00295
gene id: 196164:CE_RS00295
uniprot id: Q8FUL3
names: Similarity
messages: Belongs to the UPF0232 family.

196164:CE RS01055
gene id: 196164:CE_RS01055
uniprot id: Q8FU59
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 85 family.
messages: Cell membrane
messages: Membrane

196164:CE RS03560
gene id: 196164:CE_RS03560
uniprot id: Q8FRS3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

196164:CE RS12105
gene id: 196164:CE_RS12105
uniprot id: Q8FMQ7
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

196164:CE RS02385
gene id: 196164:CE_RS02385
uniprot id: Q8FSF2
names: Function
names: Similarity
messages: Belongs to the bacterial two-domain DSD family.
messages: Catalyzes the conversion of 3-dehydroshikimate to protocatechuate (3,4-dihydroxybenzoate), a common intermediate of quinate and shikimate degradation pathways.

196164:CE RS12385
gene id: 196164:CE_RS12385
uniprot id: I1SBB5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the diaminopimelate dehydrogenase family.
messages: Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L-tetrahydrodipicolinate, to generate the meso compound, D,L-2,6-diaminopimelate.
messages: Homodimer.

196164:CE RS01025
gene id: 196164:CE_RS01025
uniprot id: Q8FU65
names: Subcellular Location Annotation
messages: Membrane

196164:CE RS09125
gene id: 196164:CE_RS09125
uniprot id: Q8FPF2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).

196164:CE RS09255
gene id: 196164:CE_RS09255
uniprot id: Q8FPC9
names: Subcellular Location Annotation
messages: Membrane

196164:CE RS14395
gene id: 196164:CE_RS14395
uniprot id: Q8FSW7
names: Similarity
messages: Belongs to the UPF0301 (AlgH) family.

196164:CE RS05485
gene id: 196164:CE_RS05485
uniprot id: Q8FQP2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

196164:CE RS08520
gene id: 196164:CE_RS08520
uniprot id: Q8FT60
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

196164:CE RS02770
gene id: 196164:CE_RS02770
uniprot id: Q8FS80
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

196164:CE RS03865
gene id: 196164:CE_RS03865
uniprot id: Q8FRL1
names: Similarity
messages: Belongs to the AHA1 family.

196164:CE RS10195
gene id: 196164:CE_RS10195
uniprot id: Q8FNT9
names: Subcellular Location Annotation
messages: Membrane

196164:CE RS08565
gene id: 196164:CE_RS08565
uniprot id: Q8FT51
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

196164:CE RS03210
gene id: 196164:CE_RS03210
uniprot id: Q8FRZ6
names: Similarity
messages: Belongs to the FAD-binding monooxygenase family.

196164:CE RS00690
gene id: 196164:CE_RS00690
uniprot id: Q8FUD1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. Biotin synthase family.
messages: Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
messages: Homodimer.

196164:CE RS02670
gene id: 196164:CE_RS02670
uniprot id: Q8FS96
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

196164:CE RS11615
gene id: 196164:CE_RS11615
uniprot id: Q8FN00
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.
messages: Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).
messages: The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.
messages: The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1.

196164:CE RS03500
gene id: 196164:CE_RS03500
uniprot id: Q8FRT5
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

196164:CE RS01830
gene id: 196164:CE_RS01830
uniprot id: Q8FSR6
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

196164:CE RS09430
gene id: 196164:CE_RS09430
uniprot id: Q8FP95
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family.

196164:CE RS06605
gene id: 196164:CE_RS06605
uniprot id: Q8FQ20
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

196164:CE RS03090
gene id: 196164:CE_RS03090
uniprot id: Q8FS20
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

196164:CE RS12725
gene id: 196164:CE_RS12725
uniprot id: Q8FMD8
names: Subcellular Location Annotation
messages: Membrane

196164:CE RS06080
gene id: 196164:CE_RS06080
uniprot id: Q8FQB7
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

196164:CE RS03005
gene id: 196164:CE_RS03005
uniprot id: Q8FS35
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

196164:CE RS06815
gene id: 196164:CE_RS06815
uniprot id: Q8RQM5
names: Function
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.
messages: Positively regulates the expression of the exporter LysE.

196164:CE RS05965
gene id: 196164:CE_RS05965
uniprot id: Q8FQD9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatB family.
messages: Cell membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

196164:CE RS04465
gene id: 196164:CE_RS04465
uniprot id: Q8FR93
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

196164:CE RS09935
gene id: 196164:CE_RS09935
uniprot id: Q8FNZ4
names: Subcellular Location Annotation
messages: Membrane

196164:CE RS03580
gene id: 196164:CE_RS03580
uniprot id: Q8FRR9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0126 family.
messages: Membrane

196164:CE RS11255
gene id: 196164:CE_RS11255
uniprot id: Q8FN76
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

196164:CE RS09840
gene id: 196164:CE_RS09840
uniprot id: Q8FP12
names: Subcellular Location Annotation
messages: Membrane

196164:CE RS08705
gene id: 196164:CE_RS08705
uniprot id: Q8FT23
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

196164:CE RS02520
gene id: 196164:CE_RS02520
uniprot id: Q8FSC5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MenA family. Type 1 subfamily.
messages: Cell membrane
messages: Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

196164:CE RS11600
gene id: 196164:CE_RS11600
uniprot id: Q8FN03
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

196164:CE RS01320
gene id: 196164:CE_RS01320
uniprot id: Q8FU12
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

196164:CE RS13210
gene id: 196164:CE_RS13210
uniprot id: Q8FM41
names: Subcellular Location Annotation
messages: Membrane

196164:CE RS04575
gene id: 196164:CE_RS04575
uniprot id: Q8FR73
names: Similarity
messages: Belongs to the helicase family. RAD25/XPB subfamily.

196164:CE RS02850
gene id: 196164:CE_RS02850
uniprot id: Q8FS66
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FdhD family.
messages: Cytoplasm
messages: Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH.

196164:CE RS10295
gene id: 196164:CE_RS10295
uniprot id: Q8FNS0
names: Cofactor
names: Function
names: Subunit
messages: Binds 1 Mg(2+) ion per subunit.
messages: Exonuclease that cleaves single-stranded 3' overhangs of double-stranded RNA.
messages: Homodimer.

196164:CE RS01035
gene id: 196164:CE_RS01035
uniprot id: Q8FU63
names: Similarity
messages: Belongs to the glutamate synthase family.

196164:CE RS09215
gene id: 196164:CE_RS09215
uniprot id: Q8RQL6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial solute-binding protein 3 family.
messages: Cell membrane
messages: Part of the ABC transporter complex GluABCD involved in glutamate uptake (By similarity). Binds glutamate with a high affinity (By similarity).
messages: The complex is composed of two ATP-binding proteins (GluA), two transmembrane proteins (GluC and GluD) and a solute-binding protein (GluB).

196164:CE RS12295
gene id: 196164:CE_RS12295
uniprot id: Q8FMM3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FGAMS family.
messages: Cytoplasm
messages: Monomer. Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

196164:CE RS10205
gene id: 196164:CE_RS10205
uniprot id: Q8FNT7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane

196164:CE RS09645
gene id: 196164:CE_RS09645
uniprot id: Q8FP52
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ThiG family.
messages: Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
messages: Cytoplasm
messages: Homotetramer. Forms heterodimers with either ThiH or ThiS.

196164:CE RS12775
gene id: 196164:CE_RS12775
uniprot id: Q8FMC8
names: Cofactor
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.
messages: Probably binds two magnesium or manganese ions per subunit.

196164:CE RS06145
gene id: 196164:CE_RS06145
uniprot id: Q8FQA4
names: Cofactor
names: Similarity
messages: Belongs to the alkaline phosphatase family.
messages: Binds 1 Mg(2+) ion.
messages: Binds 2 Zn(2+) ions.

196164:CE RS01965
gene id: 196164:CE_RS01965
uniprot id: Q8FSN9
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

196164:CE RS01375
gene id: 196164:CE_RS01375
uniprot id: Q8FU01
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

196164:CE RS08510
gene id: 196164:CE_RS08510
uniprot id: Q8FT62
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gluconeogenesis factor family.
messages: Cytoplasm
messages: Required for morphogenesis under gluconeogenic growth conditions.

196164:CE RS13805
gene id: 196164:CE_RS13805
uniprot id: Q8FLR8
names: Similarity
messages: To bacterial alkanal monooxygenase alpha and beta chains.

196164:CE RS05365
gene id: 196164:CE_RS05365
uniprot id: Q8FQR7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl-inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics.
messages: Belongs to the MshB deacetylase family. Mca subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Monomer.

196164:CE RS04705
gene id: 196164:CE_RS04705
uniprot id: Q8FR48
names: Similarity
messages: Belongs to the dihydrofolate reductase family.

196164:CE RS07810
gene id: 196164:CE_RS07810
uniprot id: Q8FTK0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZIP transporter (TC 2.A.5) family. ZupT subfamily.
messages: Cell membrane
messages: Mediates zinc uptake. May also transport other divalent cations.

196164:CE RS05670
gene id: 196164:CE_RS05670
uniprot id: Q8FQK5
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

196164:CE RS08035
gene id: 196164:CE_RS08035
uniprot id: Q8FTF8
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

196164:CE RS10785
gene id: 196164:CE_RS10785
uniprot id: Q8FNH1
names: Similarity
messages: Belongs to the dGTPase family. Type 2 subfamily.

196164:CE RS11185
gene id: 196164:CE_RS11185
uniprot id: Q8FN92
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein uL14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein uL14 (rplN).

196164:CE RS08975
gene id: 196164:CE_RS08975
uniprot id: Q8FPI1
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

196164:CE RS02580
gene id: 196164:CE_RS02580
uniprot id: Q8FSB3
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2).

196164:CE RS09855
gene id: 196164:CE_RS09855
uniprot id: Q8FP10
names: Similarity
messages: Belongs to the glycerate kinase type-1 family.

196164:CE RS10985
gene id: 196164:CE_RS10985
uniprot id: Q8FND1
names: Similarity
messages: To bacterial alkanal monooxygenase alpha and beta chains.

196164:CE RS00545
gene id: 196164:CE_RS00545
uniprot id: Q8FUG3
names: Similarity
messages: Belongs to the CsoR family.

196164:CE RS07550
gene id: 196164:CE_RS07550
uniprot id: Q8FTP6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

196164:CE RS09850
gene id: 196164:CE_RS09850
uniprot id: Q8RQP4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
messages: Catalyzes the reversible oxidative deamination of glutamate to alpha-ketoglutarate and ammonia.
messages: Homohexamer.

196164:CE RS11080
gene id: 196164:CE_RS11080
uniprot id: Q8RQN6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the isocitrate lyase/PEP mutase superfamily. Isocitrate lyase family.
messages: Homotetramer.
messages: Involved in the metabolic adaptation in response to environmental changes. Catalyzes the reversible formation of succinate and glyoxylate from isocitrate, a key step of the glyoxylate cycle, which operates as an anaplerotic route for replenishing the tricarboxylic acid cycle during growth on fatty acid substrates.

196164:CE RS02295
gene id: 196164:CE_RS02295
uniprot id: Q8FSH1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyltransferase group 1 family. MshA subfamily.
messages: Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2-acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway.
messages: Homodimer.

196164:CE RS11775
gene id: 196164:CE_RS11775
uniprot id: Q8FMX0
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

196164:CE RS01875
gene id: 196164:CE_RS01875
uniprot id: Q8FSQ7
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

196164:CE RS11595
gene id: 196164:CE_RS11595
uniprot id: Q8FN04
names: Similarity
messages: Belongs to the truncated hemoglobin family. Group II subfamily.

196164:CE RS08155
gene id: 196164:CE_RS08155
uniprot id: Q8FTD2
names: Domain
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 dependent methionine synthase family.
messages: Catalyzes the transfer of a methyl group from methyl-cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
messages: Modular enzyme with four functionally distinct domains. The isolated Hcy-binding domain catalyzes methyl transfer from free methylcobalamin to homocysteine. The Hcy-binding domain in association with the pterin-binding domain catalyzes the methylation of cob(I)alamin by methyltetrahydrofolate and the methylation of homocysteine. The B12-binding domain binds the cofactor. The AdoMet activation domain binds S-adenosyl-L-methionine. Under aerobic conditions cob(I)alamin can be converted to inactive cob(II)alamin. Reductive methylation by S-adenosyl-L-methionine and flavodoxin regenerates methylcobalamin.

196164:CE RS12230
gene id: 196164:CE_RS12230
uniprot id: Q8FMN6
names: Similarity
messages: Belongs to the PstS family.

196164:CE RS12275
gene id: 196164:CE_RS12275
uniprot id: Q8FMM7
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.

196164:CE RS09820
gene id: 196164:CE_RS09820
uniprot id: Q8FP17
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FPG family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
messages: Monomer.

196164:CE RS12300
gene id: 196164:CE_RS12300
uniprot id: Q8FMM2
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

196164:CE RS13080
gene id: 196164:CE_RS13080
uniprot id: Q8FM65
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAPS reductase family. CysH subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of sulfite from adenosine 5'-phosphosulfate (APS) using thioredoxin as an electron donor.
messages: Cytoplasm

196164:CE RS07480
gene id: 196164:CE_RS07480
uniprot id: Q8FTR2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

196164:CE RS06845
gene id: 196164:CE_RS06845
uniprot id: Q8FPX4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

196164:CE RS02745
gene id: 196164:CE_RS02745
uniprot id: Q8FS84
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

196164:CE RS06510
gene id: 196164:CE_RS06510
uniprot id: Q8FQ39
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
messages: Cell membrane
messages: Membrane

196164:CE RS00285
gene id: 196164:CE_RS00285
uniprot id: Q8FUL5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

196164:CE RS13745
gene id: 196164:CE_RS13745
uniprot id: Q8FLT1
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

196164:CE RS12200
gene id: 196164:CE_RS12200
uniprot id: Q8FMP2
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

196164:CE RS06745
gene id: 196164:CE_RS06745
uniprot id: Q8FPZ1
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

196164:CE RS12070
gene id: 196164:CE_RS12070
uniprot id: Q8FMR1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.

196164:CE RS02790
gene id: 196164:CE_RS02790
uniprot id: P66483
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

196164:CE RS00380
gene id: 196164:CE_RS00380
uniprot id: Q8FUJ8
names: Subcellular Location Annotation
messages: Membrane

196164:CE RS02390
gene id: 196164:CE_RS02390
uniprot id: Q8FSF1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

196164:CE RS13965
gene id: 196164:CE_RS13965
uniprot id: Q8FLN6
names: Similarity
messages: Belongs to the UPF0371 family.

196164:CE RS01290
gene id: 196164:CE_RS01290
uniprot id: Q8FU17
names: Subcellular Location Annotation
messages: Membrane

196164:CE RS03320
gene id: 196164:CE_RS03320
uniprot id: Q8FRX2
names: Subcellular Location Annotation
messages: Membrane

196164:CE RS08840
gene id: 196164:CE_RS08840
uniprot id: Q8FPK2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

196164:CE RS10445
gene id: 196164:CE_RS10445
uniprot id: Q8FNP0
names: Similarity
messages: Belongs to the glutamine synthetase family.

196164:CE RS05435
gene id: 196164:CE_RS05435
uniprot id: Q8FQQ3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LamB/PxpA family.
messages: Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.
messages: Forms a complex composed of PxpA, PxpB and PxpC.

196164:CE RS06315
gene id: 196164:CE_RS06315
uniprot id: Q8FQ75
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Amino acid transporter (AAT) (TC 2.A.3.1) family.
messages: Membrane

196164:CE RS04920
gene id: 196164:CE_RS04920
uniprot id: Q8FR07
names: Subcellular Location Annotation
messages: Membrane

196164:CE RS08090
gene id: 196164:CE_RS08090
uniprot id: Q8FTE5
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic ubiquitin-like protein family.
messages: Protein modifier that is covalently attached to lysine residues of substrate proteins, thereby targeting them for proteasomal degradation. The tagging system is termed pupylation.
messages: Strongly interacts with the proteasome-associated ATPase ARC through a hydrophobic interface; the interacting region of Pup lies in its C-terminal half. There is one Pup binding site per ARC hexamer ring.
messages: The N-terminal unstructured half of Pup provides a signal required to initiate unfolding and degradation by the proteasome but is not needed for pupylation, while the C-terminal helical half of Pup interacts with ARC to target proteins to the proteasome.

196164:CE RS03710
gene id: 196164:CE_RS03710
uniprot id: Q8FRP1
names: Similarity
messages: Belongs to the citrate synthase family.

196164:CE RS04180
gene id: 196164:CE_RS04180
uniprot id: Q8FRE8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
messages: Forms a membrane-associated complex with FtsE.
messages: Membrane
messages: Part of the ABC transporter FtsEX involved in cellular division.

196164:CE RS07710
gene id: 196164:CE_RS07710
uniprot id: Q8FTL7
names: Similarity
messages: Belongs to the TlyA family.

196164:CE RS07745
gene id: 196164:CE_RS07745
uniprot id: Q7ZAN4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerD subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

196164:CE RS00345
gene id: 196164:CE_RS00345
uniprot id: Q8FUK3
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

196164:CE RS03150
gene id: 196164:CE_RS03150
uniprot id: Q8FS07
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

196164:CE RS08605
gene id: 196164:CE_RS08605
uniprot id: Q8FT43
names: Similarity
messages: Belongs to the OMP decarboxylase family. Type 2 subfamily.

196164:CE RS09285
gene id: 196164:CE_RS09285
uniprot id: Q8FPC3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TerC family.
messages: Membrane

196164:CE RS00615
gene id: 196164:CE_RS00615
uniprot id: Q8FUE8
names: Function
names: Similarity
messages: Belongs to the catalase family. HPII subfamily.
messages: Serves to protect cells from the toxic effects of hydrogen peroxide.

196164:CE RS02010
gene id: 196164:CE_RS02010
uniprot id: Q8FSN0
names: Similarity
messages: Belongs to the peptidase M1 family.

196164:CE RS06290
gene id: 196164:CE_RS06290
uniprot id: Q8FQ80
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Membrane

196164:CE RS12215
gene id: 196164:CE_RS12215
uniprot id: Q8FMN9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family.
messages: Cell membrane
messages: Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system.
messages: The complex is composed of two ATP-binding proteins (PstB), two transmembrane proteins (PstC and PstA) and a solute-binding protein (PstS).

196164:CE RS02860
gene id: 196164:CE_RS02860
uniprot id: Q8FS64
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.

196164:CE RS02830
gene id: 196164:CE_RS02830
uniprot id: Q8FS70
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

196164:CE RS11685
gene id: 196164:CE_RS11685
uniprot id: Q8FMY7
names: Function
names: Similarity
messages: Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.
messages: Belongs to the organic radical-activating enzymes family.

196164:CE RS09325
gene id: 196164:CE_RS09325
uniprot id: Q8FPB7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

196164:CE RS03100
gene id: 196164:CE_RS03100
uniprot id: Q8FS18
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

196164:CE RS12915
gene id: 196164:CE_RS12915
uniprot id: Q8FM99
names: Subcellular Location Annotation
messages: Membrane

196164:CE RS04855
gene id: 196164:CE_RS04855
uniprot id: Q8FR20
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

196164:CE RS09505
gene id: 196164:CE_RS09505
uniprot id: Q8FP80
names: Function
names: Similarity
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).

196164:CE RS04750
gene id: 196164:CE_RS04750
uniprot id: Q8FR39
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm

196164:CE RS10175
gene id: 196164:CE_RS10175
uniprot id: Q8FNU3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

196164:CE RS03810
gene id: 196164:CE_RS03810
uniprot id: I1SBB6
names: Similarity
messages: Belongs to the AccD/PCCB family.

196164:CE RS02615
gene id: 196164:CE_RS02615
uniprot id: Q8FSA9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.

196164:CE RS03220
gene id: 196164:CE_RS03220
uniprot id: Q8FRZ3
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

196164:CE RS08875
gene id: 196164:CE_RS08875
uniprot id: Q8FPJ5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Catalyzes the conjugation of the 1'-hydroxyl group of D-myo-inositol-3-phosphate (also named L-myo-inositol-1-phosphate) with a lipid tail of cytidine diphosphate diacylglycerol (CDP-DAG), forming phosphatidylinositol phosphate (PIP) and CMP. PIP is a precursor of phosphatidylinositol (PI) which is an essential lipid required for cell wall formation.
messages: Cell membrane
messages: Contains a di-nuclear catalytic Mg(2+) center.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

196164:CE RS06535
gene id: 196164:CE_RS06535
uniprot id: Q8FQ34
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. MoaA family.
messages: Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.
messages: Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
messages: Monomer and homodimer.

196164:CE RS06010
gene id: 196164:CE_RS06010
uniprot id: Q8CM29
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

196164:CE RS09330
gene id: 196164:CE_RS09330
uniprot id: Q8FPB6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

196164:CE RS09910
gene id: 196164:CE_RS09910
uniprot id: Q8FNZ9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

196164:CE RS03455
gene id: 196164:CE_RS03455
uniprot id: Q8FRU5
names: Function
names: Similarity
messages: Belongs to the phenylacetyl-CoA ligase family.
messages: Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA).

196164:CE RS13190
gene id: 196164:CE_RS13190
uniprot id: Q8FM44
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dCTP deaminase family.
messages: Bifunctional enzyme that catalyzes both the deamination of dCTP to dUTP and the hydrolysis of dUTP to dUMP without releasing the toxic dUTP intermediate.
messages: Homotrimer.

196164:CE RS14430
gene id: 196164:CE_RS14430
uniprot id: Q8FSW0
names: Similarity
messages: Belongs to the thioredoxin family.

196164:CE RS04060
gene id: 196164:CE_RS04060
uniprot id: Q8FRH1
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

196164:CE RS02225
gene id: 196164:CE_RS02225
uniprot id: Q8FSI5
names: Similarity
messages: Belongs to the CsoR family.

196164:CE RS12010
gene id: 196164:CE_RS12010
uniprot id: Q8FMS1
names: Similarity
messages: Belongs to the fructosamine kinase family.

196164:CE RS01405
gene id: 196164:CE_RS01405
uniprot id: Q8FTZ5
names: Subcellular Location Annotation
messages: Membrane

196164:CE RS07945
gene id: 196164:CE_RS07945
uniprot id: Q8FTH6
names: Similarity
messages: Belongs to the NADH dehydrogenase family.

196164:CE RS05155
gene id: 196164:CE_RS05155
uniprot id: Q8FQV9
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

196164:CE RS10335
gene id: 196164:CE_RS10335
uniprot id: Q8FNR2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome b family.
messages: Binds 2 heme groups non-covalently per subunit.
messages: Cell membrane
messages: Cytochrome b subunit of the cytochrome bc1 complex, an essential component of the respiratory electron transport chain required for ATP synthesis. The bc1 complex catalyzes the oxidation of menaquinol and the reduction of cytochrome c in the respiratory chain. The bc1 complex operates through a Q-cycle mechanism that couples electron transfer to generation of the proton gradient that drives ATP synthesis.
messages: The cytochrome bc1 complex is composed of a cytochrome b (QcrB), the Rieske protein iron-sulfur (QcrA) and a diheme cytochrome c (QcrC) subunit.

196164:CE RS04185
gene id: 196164:CE_RS04185
uniprot id: Q8FRE7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

196164:CE RS02980
gene id: 196164:CE_RS02980
uniprot id: Q8FS40
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

196164:CE RS04160
gene id: 196164:CE_RS04160
uniprot id: Q8FRF2
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

196164:CE RS02195
gene id: 196164:CE_RS02195
uniprot id: Q8FSJ1
names: Function
names: Similarity
messages: Belongs to the PurU family.
messages: Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).

196164:CE RS03860
gene id: 196164:CE_RS03860
uniprot id: Q8FRL2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

196164:CE RS01335
gene id: 196164:CE_RS01335
uniprot id: Q8FU09
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CobB/CobQ family. GatD subfamily.
messages: Forms a heterodimer with MurT.
messages: The lipid II isoglutaminyl synthase complex catalyzes the formation of alpha-D-isoglutamine in the cell wall lipid II stem peptide. The GatD subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia. The resulting ammonia molecule is channeled to the active site of MurT.

196164:CE RS01960
gene id: 196164:CE_RS01960
uniprot id: Q8FSP0
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

196164:CE RS12235
gene id: 196164:CE_RS12235
uniprot id: Q8FMN5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetyltransferase family. MshD subfamily.
messages: Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol.
messages: Monomer.

196164:CE RS00625
gene id: 196164:CE_RS00625
uniprot id: Q8FUE5
names: Subcellular Location Annotation
messages: Membrane

196164:CE RS03780
gene id: 196164:CE_RS03780
uniprot id: Q8FRM9
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

196164:CE RS03160
gene id: 196164:CE_RS03160
uniprot id: Q8CY28
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

196164:CE RS08655
gene id: 196164:CE_RS08655
uniprot id: Q8FT34
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

196164:CE RS02380
gene id: 196164:CE_RS02380
uniprot id: Q8FSF3
names: Subcellular Location Annotation
messages: Membrane

196164:CE RS00440
gene id: 196164:CE_RS00440
uniprot id: Q8FUI5
names: Similarity
messages: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.

196164:CE RS06600
gene id: 196164:CE_RS06600
uniprot id: Q8FQ21
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

196164:CE RS05050
gene id: 196164:CE_RS05050
uniprot id: Q8FQY1
names: Subcellular Location Annotation
messages: Membrane

196164:CE RS09815
gene id: 196164:CE_RS09815
uniprot id: Q8FP18
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell membrane
messages: Membrane

196164:CE RS14425
gene id: 196164:CE_RS14425
uniprot id: Q8FSW1
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

196164:CE RS07780
gene id: 196164:CE_RS07780
uniprot id: Q8FTK6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

196164:CE RS08270
gene id: 196164:CE_RS08270
uniprot id: Q8FTB1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferrochelatase family.
messages: Cytoplasm
messages: Involved in coproporphyrin-dependent heme b biosynthesis. Catalyzes the insertion of ferrous iron into coproporphyrin III to form Fe-coproporphyrin III.

196164:CE RS07615
gene id: 196164:CE_RS07615
uniprot id: Q8FTN3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm

196164:CE RS00820
gene id: 196164:CE_RS00820
uniprot id: Q8FUA6
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

196164:CE RS06370
gene id: 196164:CE_RS06370
uniprot id: Q8FQ64
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit B family.

196164:CE RS03340
gene id: 196164:CE_RS03340
uniprot id: Q8FRW8
names: Similarity
messages: Belongs to the carotenoid/retinoid oxidoreductase family.

196164:CE RS11935
gene id: 196164:CE_RS11935
uniprot id: Q8FMT7
names: Function
names: PTM
names: Similarity
messages: Belongs to the NAPRTase family.
messages: Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate.
messages: Transiently phosphorylated on a His residue during the reaction cycle. Phosphorylation strongly increases the affinity for substrates and increases the rate of nicotinate D-ribonucleotide production. Dephosphorylation regenerates the low-affinity form of the enzyme, leading to product release.

196164:CE RS02925
gene id: 196164:CE_RS02925
uniprot id: Q8FS51
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

196164:CE RS14040
gene id: 196164:CE_RS14040
uniprot id: Q8FLM0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm

196164:CE RS08820
gene id: 196164:CE_RS08820
uniprot id: Q8FPK6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YajC family.
messages: Membrane

196164:CE RS03025
gene id: 196164:CE_RS03025
uniprot id: Q8FS32
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

196164:CE RS07335
gene id: 196164:CE_RS07335
uniprot id: Q8CM46
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

196164:CE RS05395
gene id: 196164:CE_RS05395
uniprot id: Q8FQR1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.

196164:CE RS03600
gene id: 196164:CE_RS03600
uniprot id: Q8FRR5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

196164:CE RS04500
gene id: 196164:CE_RS04500
uniprot id: Q8FR86
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arsenical resistance-3 (ACR3) (TC 2.A.59) family.
messages: Cell membrane
messages: Membrane

196164:CE RS05315
gene id: 196164:CE_RS05315
uniprot id: Q8FQS7
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

196164:CE RS01700
gene id: 196164:CE_RS01700
uniprot id: Q8FST9
names: Subcellular Location Annotation
messages: Membrane

196164:CE RS02030
gene id: 196164:CE_RS02030
uniprot id: Q8FSM6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the etk/wzc family.
messages: Cell inner membrane
messages: Membrane

196164:CE RS13465
gene id: 196164:CE_RS13465
uniprot id: Q8FLY8
names: Activity Regulation
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Inhibited by fructose 1,6-bisphosphate (FBP).
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.

196164:CE RS07805
gene id: 196164:CE_RS07805
uniprot id: Q8FTK1
names: Subcellular Location Annotation
messages: Membrane

196164:CE RS09625
gene id: 196164:CE_RS09625
uniprot id: Q8FP56
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

196164:CE RS06690
gene id: 196164:CE_RS06690
uniprot id: Q8FQ03
names: Similarity
messages: Belongs to the spermidine/spermine synthase family.

196164:CE RS08185
gene id: 196164:CE_RS08185
uniprot id: Q8FTC6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
messages: Cell membrane
messages: Monomer.

196164:CE RS10940
gene id: 196164:CE_RS10940
uniprot id: Q8FNE1
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

196164:CE RS04885
gene id: 196164:CE_RS04885
uniprot id: Q8FR14
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscL family.
messages: Cell membrane
messages: Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
messages: Homopentamer.
messages: Membrane

196164:CE RS06750
gene id: 196164:CE_RS06750
uniprot id: Q8FPZ0
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

196164:CE RS09570
gene id: 196164:CE_RS09570
uniprot id: Q8FP66
names: Similarity
messages: Belongs to the UPF0102 family.

196164:CE RS02905
gene id: 196164:CE_RS02905
uniprot id: Q8FS55
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

196164:CE RS11110
gene id: 196164:CE_RS11110
uniprot id: Q8FNA6
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

196164:CE RS05795
gene id: 196164:CE_RS05795
uniprot id: Q8FQH8
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the peroxiredoxin family. Tpx subfamily.
messages: Homodimer.
messages: The active site is a conserved redox-active cysteine residue, the peroxidatic cysteine (C(P)), which makes the nucleophilic attack on the peroxide substrate. The peroxide oxidizes the C(P)-SH to cysteine sulfenic acid (C(P)-SOH), which then reacts with another cysteine residue, the resolving cysteine (C(R)), to form a disulfide bridge. The disulfide is subsequently reduced by an appropriate electron donor to complete the catalytic cycle. In this atypical 2-Cys peroxiredoxin, C(R) is present in the same subunit to form an intramolecular disulfide. The disulfide is subsequently reduced by thioredoxin.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

196164:CE RS08495
gene id: 196164:CE_RS08495
uniprot id: Q8FT66
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Monomer.

196164:CE RS11895
gene id: 196164:CE_RS11895
uniprot id: Q8FMU6
names: Function
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.
messages: Provides the (R)-glutamate required for cell wall biosynthesis.

196164:CE RS00455
gene id: 196164:CE_RS00455
uniprot id: Q8FUI2
names: Subcellular Location Annotation
messages: Membrane

196164:CE RS07940
gene id: 196164:CE_RS07940
uniprot id: Q8FTH7
names: Function
names: Similarity
messages: Belongs to the Thz kinase family.
messages: Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ).

196164:CE RS04645
gene id: 196164:CE_RS04645
uniprot id: Q8FR58
names: Similarity
messages: Belongs to the AccD/PCCB family.

196164:CE RS12940
gene id: 196164:CE_RS12940
uniprot id: Q8FM94
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent (By similarity).
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE. Acts before DnaK, in the processing of protein aggregates. Protein binding stimulates the ATPase activity; ATP hydrolysis unfolds the denatured protein aggregates, which probably helps expose new hydrophobic binding sites on the surface of ClpB-bound aggregates, contributing to the solubilization and refolding of denatured protein aggregates by DnaK (By similarity).
messages: The Clp repeat (R) domain probably functions as a substrate-discriminating domain, recruiting aggregated proteins to the ClpB hexamer and/or stabilizing bound proteins. The NBD2 domain is responsible for oligomerization, whereas the NBD1 domain stabilizes the hexamer probably in an ATP-dependent manner. The movement of the coiled-coil domain is essential for ClpB ability to rescue proteins from an aggregated state, probably by pulling apart large aggregated proteins, which are bound between the coiled-coils motifs of adjacent ClpB subunits in the functional hexamer (By similarity).

196164:CE RS11190
gene id: 196164:CE_RS11190
uniprot id: Q8FN90
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

196164:CE RS03080
gene id: 196164:CE_RS03080
uniprot id: Q8FS23
names: Similarity
messages: Belongs to the WXG100 family.

196164:CE RS12475
gene id: 196164:CE_RS12475
uniprot id: Q8FMI8
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

196164:CE RS12485
gene id: 196164:CE_RS12485
uniprot id: Q8FMI6
names: Function
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily.
messages: Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.

196164:CE RS13870
gene id: 196164:CE_RS13870
uniprot id: Q8FLQ7
names: Similarity
messages: Belongs to the PspA/IM30 family.

196164:CE RS09310
gene id: 196164:CE_RS09310
uniprot id: Q8RQM9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the thymidylate synthase ThyX family.
messages: Binds 4 FAD per tetramer. Each FAD binding site is formed by three monomers.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant.
messages: Homotetramer.

196164:CE RS09220
gene id: 196164:CE_RS09220
uniprot id: Q8RQL5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Part of the ABC transporter complex GluABCD involved in glutamate uptake. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (GluA), two transmembrane proteins (GluC and GluD) and a solute-binding protein (GluB).

196164:CE RS04835
gene id: 196164:CE_RS04835
uniprot id: Q8FR24
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

196164:CE RS09140
gene id: 196164:CE_RS09140
uniprot id: Q8FPE9
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

196164:CE RS02230
gene id: 196164:CE_RS02230
uniprot id: Q8FSI4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane
messages: Membrane

196164:CE RS08460
gene id: 196164:CE_RS08460
uniprot id: Q8FT72
names: Function
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.
messages: Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.

196164:CE RS03000
gene id: 196164:CE_RS03000
uniprot id: Q8FS36
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

196164:CE RS14460
gene id: 196164:CE_RS14460
uniprot id: Q8FSV3
names: Similarity
messages: Belongs to the ParB family.

196164:CE RS02915
gene id: 196164:CE_RS02915
uniprot id: Q8FS53
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

196164:CE RS11645
gene id: 196164:CE_RS11645
uniprot id: Q8FMZ5
names: Subcellular Location Annotation
messages: Membrane

196164:CE RS01380
gene id: 196164:CE_RS01380
uniprot id: Q8FU00
names: Subcellular Location Annotation
messages: Membrane

196164:CE RS14220
gene id: 196164:CE_RS14220
uniprot id: Q8FT06
names: Function
names: Similarity
messages: ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity.
messages: Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily.

196164:CE RS01545
gene id: 196164:CE_RS01545
uniprot id: Q8FTW9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HsdR family.
messages: Subunit R is required for both nuclease and ATPase activities, but not for modification.
messages: The type I restriction/modification system is composed of three polypeptides R, M and S.

196164:CE RS10280
gene id: 196164:CE_RS10280
uniprot id: Q8FNS2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 87 family.
messages: Membrane

196164:CE RS02815
gene id: 196164:CE_RS02815
uniprot id: Q8FS73
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

196164:CE RS05525
gene id: 196164:CE_RS05525
uniprot id: Q8FQN4
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

196164:CE RS11320
gene id: 196164:CE_RS11320
uniprot id: Q8FN62
names: Function
names: Similarity
messages: Belongs to the LDH/MDH superfamily. MDH type 2 family.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.

196164:CE RS07620
gene id: 196164:CE_RS07620
uniprot id: Q8FTN2
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: May also have succinyldiaminopimelate aminotransferase activity, thus carrying out the corresponding step in lysine biosynthesis.

196164:CE RS06000
gene id: 196164:CE_RS06000
uniprot id: Q8FQD2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

196164:CE RS14480
gene id: 196164:CE_RS14480
uniprot id: Q8FSU8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RnpA family.
messages: Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.
messages: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.

196164:CE RS08485
gene id: 196164:CE_RS08485
uniprot id: Q8RQL3
names: Function
names: Similarity
messages: Belongs to the PEPCase type 1 family.
messages: Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.

196164:CE RS05565
gene id: 196164:CE_RS05565
uniprot id: Q8FQM6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Membrane

196164:CE RS10230
gene id: 196164:CE_RS10230
uniprot id: Q8FNT2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

196164:CE RS03945
gene id: 196164:CE_RS03945
uniprot id: Q8FRJ4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.
messages: Cytoplasm
messages: May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.

196164:CE RS07310
gene id: 196164:CE_RS07310
uniprot id: Q8FPN2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

196164:CE RS12870
gene id: 196164:CE_RS12870
uniprot id: Q8FMA8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

196164:CE RS08670
gene id: 196164:CE_RS08670
uniprot id: Q8FT31
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
messages: Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).
messages: Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
messages: Cytoplasm

196164:CE RS12765
gene id: 196164:CE_RS12765
uniprot id: Q8FMD0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

196164:CE RS06475
gene id: 196164:CE_RS06475
uniprot id: Q8FQ45
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

196164:CE RS14495
gene id: 196164:CE_RS14495
uniprot id: Q8FUH1
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

196164:CE RS10160
gene id: 196164:CE_RS10160
uniprot id: Q8FNU6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SepF family.
messages: Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA.
messages: Cytoplasm
messages: Homodimer. Interacts with FtsZ.

196164:CE RS07955
gene id: 196164:CE_RS07955
uniprot id: Q8FTH4
names: Subcellular Location Annotation
messages: Membrane

196164:CE RS10435
gene id: 196164:CE_RS10435
uniprot id: Q8FNP2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAE transporter (TC 2.A.81) family.
messages: Cell membrane

196164:CE RS14355
gene id: 196164:CE_RS14355
uniprot id: Q8FSX8
names: Function
messages: Catalyzes the phosphorylation of hydroxymethylpyrimidine phosphate (HMP-P) to HMP-PP, and of HMP to HMP-P.

196164:CE RS03505
gene id: 196164:CE_RS03505
uniprot id: Q8FRT4
names: Function
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.
messages: Could possibly oxidize fatty acids using specific components.

196164:CE RS05675
gene id: 196164:CE_RS05675
uniprot id: Q8FQK4
names: Function
names: Similarity
messages: Belongs to the NadC/ModD family.
messages: Involved in the catabolism of quinolinic acid (QA).

196164:CE RS08580
gene id: 196164:CE_RS08580
uniprot id: Q8FT48
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

196164:CE RS10365
gene id: 196164:CE_RS10365
uniprot id: Q8FNQ6
names: Similarity
messages: Belongs to the asparagine synthetase family.

196164:CE RS05190
gene id: 196164:CE_RS05190
uniprot id: Q8FQV1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
messages: Cytoplasm
messages: Homotrimer.
messages: In the C-terminal section; belongs to the transferase hexapeptide repeat family.
messages: In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.

196164:CE RS09160
gene id: 196164:CE_RS09160
uniprot id: Q8FPE5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

196164:CE RS08560
gene id: 196164:CE_RS08560
uniprot id: Q8FT52
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

196164:CE RS13785
gene id: 196164:CE_RS13785
uniprot id: Q8FLS3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Cell membrane
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration (By similarity).
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins (By similarity).

196164:CE RS12690
gene id: 196164:CE_RS12690
uniprot id: Q8CY22
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

196164:CE RS14115
gene id: 196164:CE_RS14115
uniprot id: Q8FLK6
names: Subcellular Location Annotation
messages: Membrane

196164:CE RS10150
gene id: 196164:CE_RS10150
uniprot id: Q8FNU8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DivIVA family.
messages: Cytoplasm

196164:CE RS08635
gene id: 196164:CE_RS08635
uniprot id: Q8FT37
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. SDR39U1 subfamily.

196164:CE RS08695
gene id: 196164:CE_RS08695
uniprot id: Q8FT25
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transglycosylase MltG family.
messages: Cell membrane
messages: Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.

196164:CE RS10055
gene id: 196164:CE_RS10055
uniprot id: Q8FNW7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the serine/threonine dehydratase family.
messages: Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.
messages: Homotetramer.

196164:CE RS12130
gene id: 196164:CE_RS12130
uniprot id: Q8FMQ4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

196164:CE RS06960
gene id: 196164:CE_RS06960
uniprot id: Q8FPU9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Monomer.

196164:CE RS10865
gene id: 196164:CE_RS10865
uniprot id: Q8FNF5
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

196164:CE RS09225
gene id: 196164:CE_RS09225
uniprot id: Q8RQL4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Part of the ABC transporter complex GluABCD involved in glutamate uptake. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (GluA), two transmembrane proteins (GluC and GluD) and a solute-binding protein (GluB).

196164:CE RS06955
gene id: 196164:CE_RS06955
uniprot id: Q8FPV0
names: Similarity
messages: Belongs to the isochorismate synthase family.

196164:CE RS12250
gene id: 196164:CE_RS12250
uniprot id: Q8FMN2
names: Caution
names: Similarity
messages: Belongs to the nitrobindin family.
messages: Lacks the conserved His residue that binds heme iron in the nitrobindin family.

196164:CE RS05560
gene id: 196164:CE_RS05560
uniprot id: Q8FQM7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

196164:CE RS07510
gene id: 196164:CE_RS07510
uniprot id: Q8FTQ6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

196164:CE RS01775
gene id: 196164:CE_RS01775
uniprot id: Q8FSS6
names: Subcellular Location Annotation
messages: Cytoplasm

196164:CE RS09610
gene id: 196164:CE_RS09610
uniprot id: Q8FP59
names: Subcellular Location Annotation
messages: Membrane

196164:CE RS00445
gene id: 196164:CE_RS00445
uniprot id: Q8FUI4
names: Similarity
messages: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.

196164:CE RS08290
gene id: 196164:CE_RS08290
uniprot id: Q8FTA6
names: Function
names: Subunit
messages: AcnR negatively controls the expression of the aconitase gene acn.
messages: Homodimer.

196164:CE RS05085
gene id: 196164:CE_RS05085
uniprot id: Q8FQX4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the urease gamma subunit family.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

196164:CE RS02360
gene id: 196164:CE_RS02360
uniprot id: Q8FSF7
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HMBS family.
messages: Binds 1 dipyrromethane group covalently.
messages: Monomer.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
messages: The porphobilinogen subunits are added to the dipyrromethane group.

196164:CE RS12605
gene id: 196164:CE_RS12605
uniprot id: Q8FMG3
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family.
messages: Toroid-shaped homodecamer, composed of two pentamers of five dimers.

196164:CE RS07185
gene id: 196164:CE_RS07185
uniprot id: Q8FPQ5
names: Caution
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the thiamine-monophosphate kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate.

196164:CE RS08685
gene id: 196164:CE_RS08685
uniprot id: Q8FT27
names: Similarity
messages: Belongs to the peptidase A24 family.

196164:CE RS09925
gene id: 196164:CE_RS09925
uniprot id: Q8FNZ6
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

196164:CE RS06855
gene id: 196164:CE_RS06855
uniprot id: Q8FPX2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

196164:CE RS06320
gene id: 196164:CE_RS06320
uniprot id: Q8FQ74
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DEAD box helicase family. DeaD/CsdA subfamily.
messages: Cytoplasm
messages: DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation.

196164:CE RS13615
gene id: 196164:CE_RS13615
uniprot id: Q8FLV7
names: Similarity
messages: Belongs to the pyruvate kinase family.

196164:CE RS09955
gene id: 196164:CE_RS09955
uniprot id: Q8FNZ0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.

196164:CE RS09425
gene id: 196164:CE_RS09425
uniprot id: Q8FP96
names: Similarity
messages: Belongs to the UPF0246 family.

196164:CE RS05945
gene id: 196164:CE_RS05945
uniprot id: Q8FQE4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
messages: Homotetramer.
messages: Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc.

196164:CE RS12195
gene id: 196164:CE_RS12195
uniprot id: Q8FMP3
names: Similarity
messages: Belongs to the acetyl-CoA hydrolase/transferase family.

196164:CE RS09370
gene id: 196164:CE_RS09370
uniprot id: Q8FPA8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

196164:CE RS10285
gene id: 196164:CE_RS10285
uniprot id: Q8FNS1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 87 family.
messages: Membrane

196164:CE RS13060
gene id: 196164:CE_RS13060
uniprot id: Q8FM69
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

196164:CE RS11560
gene id: 196164:CE_RS11560
uniprot id: Q8FN11
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

196164:CE RS11975
gene id: 196164:CE_RS11975
uniprot id: Q8FMS9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferritin family. Prokaryotic subfamily.
messages: Cytoplasm
messages: Iron-storage protein.

196164:CE RS07220
gene id: 196164:CE_RS07220
uniprot id: Q8FPP8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

196164:CE RS01420
gene id: 196164:CE_RS01420
uniprot id: Q8FTZ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit F family.
messages: Cell membrane
messages: Membrane

196164:CE RS12445
gene id: 196164:CE_RS12445
uniprot id: Q8FMJ4
names: Function
names: Similarity
messages: Belongs to the trehalose phosphatase family.
messages: Removes the phosphate from trehalose 6-phosphate to produce free trehalose.

196164:CE RS12470
gene id: 196164:CE_RS12470
uniprot id: Q8FMI9
names: Similarity
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.

196164:CE RS06580
gene id: 196164:CE_RS06580
uniprot id: Q8FQ25
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Membrane

196164:CE RS09565
gene id: 196164:CE_RS09565
uniprot id: Q8FP67
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

196164:CE RS11155
gene id: 196164:CE_RS11155
uniprot id: Q8FN97
names: Subcellular Location Annotation
messages: Membrane

196164:CE RS10870
gene id: 196164:CE_RS10870
uniprot id: Q8FNF4
names: Function
names: Similarity
messages: Belongs to the HrcA family.
messages: Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons.

196164:CE RS01935
gene id: 196164:CE_RS01935
uniprot id: Q8FSP5
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

196164:CE RS08385
gene id: 196164:CE_RS08385
uniprot id: Q8FT87
names: Function
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.
messages: Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine.

196164:CE RS08085
gene id: 196164:CE_RS08085
uniprot id: Q8FTE6
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the Pup ligase/Pup deamidase family. Pup-conjugating enzyme subfamily.
messages: Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine.
messages: The reaction mechanism probably proceeds via the activation of Pup by phosphorylation of its C-terminal glutamate, which is then subject to nucleophilic attack by the substrate lysine, resulting in an isopeptide bond and the release of phosphate as a good leaving group.

196164:CE RS12345
gene id: 196164:CE_RS12345
uniprot id: Q8FML3
names: Similarity
messages: Belongs to the GARS family.

196164:CE RS08315
gene id: 196164:CE_RS08315
uniprot id: Q8FTA2
names: Similarity
messages: Belongs to the UPF0237 family.

196164:CE RS06550
gene id: 196164:CE_RS06550
uniprot id: Q8FQ31
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

196164:CE RS13095
gene id: 196164:CE_RS13095
uniprot id: Q8FM62
names: Similarity
messages: Belongs to the ferredoxin--NADP reductase type 1 family.

196164:CE RS06780
gene id: 196164:CE_RS06780
uniprot id: Q8FPY5
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

196164:CE RS11005
gene id: 196164:CE_RS11005
uniprot id: Q8FNC7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BCCT transporter (TC 2.A.15) family.
messages: Membrane

196164:CE RS13940
gene id: 196164:CE_RS13940
uniprot id: Q8FLP1
names: Similarity
messages: Belongs to the universal stress protein A family.

196164:CE RS02730
gene id: 196164:CE_RS02730
uniprot id: P59163
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Because the enzyme that would modify Asp-89 to 3-methylthioaspartic acid has not been found in the proteome of this organism, that modification is not predicted.
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

196164:CE RS00770
gene id: 196164:CE_RS00770
uniprot id: Q8FUB6
names: Subcellular Location Annotation
messages: Secreted

196164:CE RS02910
gene id: 196164:CE_RS02910
uniprot id: Q8FS54
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

196164:CE RS11330
gene id: 196164:CE_RS11330
uniprot id: Q8FN59
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

196164:CE RS07625
gene id: 196164:CE_RS07625
uniprot id: Q8FTN1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm
messages: Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline.

196164:CE RS08450
gene id: 196164:CE_RS08450
uniprot id: Q8FT74
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

196164:CE RS06415
gene id: 196164:CE_RS06415
uniprot id: Q8FQ57
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

196164:CE RS10190
gene id: 196164:CE_RS10190
uniprot id: Q8FNU0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).

196164:CE RS12700
gene id: 196164:CE_RS12700
uniprot id: Q8FME4
names: Subcellular Location Annotation
messages: Membrane

196164:CE RS12465
gene id: 196164:CE_RS12465
uniprot id: Q8FMJ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

196164:CE RS02435
gene id: 196164:CE_RS02435
uniprot id: Q8FSE3
names: Subcellular Location Annotation
messages: Membrane

196164:CE RS09810
gene id: 196164:CE_RS09810
uniprot id: Q8FP19
names: Similarity
messages: Belongs to the acylphosphatase family.

196164:CE RS09445
gene id: 196164:CE_RS09445
uniprot id: Q8FP92
names: Function
names: Similarity
messages: Belongs to the SELO family.
messages: Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr or Tyr residues of target proteins (AMPylation).

196164:CE RS13435
gene id: 196164:CE_RS13435
uniprot id: Q8FLZ4
names: Subcellular Location Annotation
messages: Membrane

196164:CE RS05175
gene id: 196164:CE_RS05175
uniprot id: Q8FQV5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

196164:CE RS07525
gene id: 196164:CE_RS07525
uniprot id: Q8FTQ1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

196164:CE RS06635
gene id: 196164:CE_RS06635
uniprot id: Q8FQ14
names: Similarity
messages: Belongs to the UPF0045 family.

196164:CE RS11400
gene id: 196164:CE_RS11400
uniprot id: Q8FN46
names: Similarity
names: Subunit
messages: Belongs to the muconolactone Delta-isomerase family.
messages: Homodecamer.

196164:CE RS04830
gene id: 196164:CE_RS04830
uniprot id: Q8FR25
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

196164:CE RS01880
gene id: 196164:CE_RS01880
uniprot id: Q8FSQ6
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase family.
messages: Belongs to the 3-oxoacid CoA-transferase subunit A family.
messages: Belongs to the 3-oxoacid CoA-transferase subunit B family.

196164:CE RS09590
gene id: 196164:CE_RS09590
uniprot id: Q8FP63
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

196164:CE RS11820
gene id: 196164:CE_RS11820
uniprot id: Q8FMW0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Cytoplasm
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

196164:CE RS06645
gene id: 196164:CE_RS06645
uniprot id: Q8FQ12
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
messages: Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.
messages: Monomer.

196164:CE RS07430
gene id: 196164:CE_RS07430
uniprot id: Q8FTS8
names: Subcellular Location Annotation
messages: Membrane

196164:CE RS03770
gene id: 196164:CE_RS03770
uniprot id: Q8FRN1
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

196164:CE RS14295
gene id: 196164:CE_RS14295
uniprot id: Q8FSZ0
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

196164:CE RS02985
gene id: 196164:CE_RS02985
uniprot id: Q8FS39
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Monomer.

196164:CE RS05100
gene id: 196164:CE_RS05100
uniprot id: Q8FQX1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UreE family.
messages: Cytoplasm
messages: Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly.

196164:CE RS11515
gene id: 196164:CE_RS11515
uniprot id: Q8FN20
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

196164:CE RS08650
gene id: 196164:CE_RS08650
uniprot id: Q8FT35
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

196164:CE RS07610
gene id: 196164:CE_RS07610
uniprot id: Q8FTN4
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArgJ family.
messages: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.
messages: Cytoplasm
messages: Heterotetramer of two alpha and two beta chains.
messages: Some bacteria possess a monofunctional ArgJ, i.e. capable of catalyzing only the fifth step of the arginine biosynthetic pathway.

196164:CE RS09095
gene id: 196164:CE_RS09095
uniprot id: Q8FPF8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

196164:CE RS03630
gene id: 196164:CE_RS03630
uniprot id: Q8FRQ8
names: Similarity
messages: Belongs to the peptidase C40 family.

196164:CE RS03815
gene id: 196164:CE_RS03815
uniprot id: Q8FRM3
names: Similarity
messages: Belongs to the AccD/PCCB family.

196164:CE RS08500
gene id: 196164:CE_RS08500
uniprot id: Q8FT65
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
messages: Cytoplasm

196164:CE RS00300
gene id: 196164:CE_RS00300
uniprot id: Q8FUL2
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Binds two Mg(2+) per subunit. The magnesium ions form salt bridges with both the protein and the DNA. Can also accept other divalent metal cations, such as Mn(2+) or Ca(2+).
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

196164:CE RS07935
gene id: 196164:CE_RS07935
uniprot id: Q8FTH8
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the phosphorylation of hydroxymethylpyrimidine phosphate (HMP-P) to HMP-PP, and of HMP to HMP-P.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).
messages: In the C-terminal section; belongs to the thiaminase-2 family.
messages: In the N-terminal section; belongs to the thiamine-phosphate synthase family.
messages: In the central section; belongs to the ThiD family.
messages: There is also a ThiE protein in this bacteria (AC Q8FP55).

196164:CE RS12715
gene id: 196164:CE_RS12715
uniprot id: Q8FME0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

196164:CE RS10360
gene id: 196164:CE_RS10360
uniprot id: Q8FNQ7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associates with subunits I, III and IV to form cytochrome c oxidase.
messages: Belongs to the cytochrome c oxidase subunit 2 family.
messages: Binds a binuclear copper A center per subunit.
messages: Cell membrane
messages: Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) (By similarity).

196164:CE RS08830
gene id: 196164:CE_RS08830
uniprot id: Q8FPK4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvA family.
messages: Cytoplasm
messages: Has three domains with a flexible linker between the domains II and III and assumes an 'L' shape. Domain III is highly mobile and contacts RuvB.
messages: Homotetramer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

196164:CE RS09545
gene id: 196164:CE_RS09545
uniprot id: Q8FP70
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

196164:CE RS06565
gene id: 196164:CE_RS06565
uniprot id: Q8FQ28
names: Subcellular Location Annotation
messages: Membrane

196164:CE RS06810
gene id: 196164:CE_RS06810
uniprot id: Q8RQM4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LysE/ArgO transporter (TC 2.A.75) family.
messages: Catalyzes the efflux of L-lysine.
messages: Cell inner membrane

196164:CE RS11350
gene id: 196164:CE_RS11350
uniprot id: Q8FN56
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit B family.

196164:CE RS03015
gene id: 196164:CE_RS03015
uniprot id: Q8FS34
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

196164:CE RS10420
gene id: 196164:CE_RS10420
uniprot id: Q8FNP5
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LipB family.
messages: Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
messages: Cytoplasm
messages: In the reaction, the free carboxyl group of octanoic acid is attached via an amide linkage to the epsilon-amino group of a specific lysine residue of lipoyl domains of lipoate-dependent enzymes.

196164:CE RS08480
gene id: 196164:CE_RS08480
uniprot id: Q8FT68
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

196164:CE RS09500
gene id: 196164:CE_RS09500
uniprot id: Q8FP81
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

196164:CE RS08195
gene id: 196164:CE_RS08195
uniprot id: Q8FTC4
names: Similarity
messages: Belongs to the UPF0098 family.

196164:CE RS09410
gene id: 196164:CE_RS09410
uniprot id: Q8FP99
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

196164:CE RS09230
gene id: 196164:CE_RS09230
uniprot id: Q8FPD4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecX family.
messages: Cytoplasm
messages: Modulates RecA activity.

196164:CE RS06860
gene id: 196164:CE_RS06860
uniprot id: Q8FPX1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.

196164:CE RS05680
gene id: 196164:CE_RS05680
uniprot id: Q8FQK3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the quinolinate synthase family. Type 3 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
messages: Cytoplasm

196164:CE RS11450
gene id: 196164:CE_RS11450
uniprot id: Q8FN36
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

196164:CE RS12040
gene id: 196164:CE_RS12040
uniprot id: Q8FMR7
names: Similarity
messages: Belongs to the phosphohexose mutase family.

196164:CE RS13005
gene id: 196164:CE_RS13005
uniprot id: Q8FM80
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

196164:CE RS10850
gene id: 196164:CE_RS10850
uniprot id: Q8FNF8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

196164:CE RS10770
gene id: 196164:CE_RS10770
uniprot id: Q8FNH4
names: Similarity
messages: Belongs to the ribonuclease N1/T1 family.

196164:CE RS02550
gene id: 196164:CE_RS02550
uniprot id: Q8FSB9
names: Caution
names: Function
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family. MenB subfamily.
messages: Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2-naphthoyl-CoA (DHNA-CoA).
messages: Could possibly oxidize fatty acids using specific components.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

196164:CE RS01410
gene id: 196164:CE_RS01410
uniprot id: Q8FTZ4
names: Subcellular Location Annotation
messages: Membrane

196164:CE RS09050
gene id: 196164:CE_RS09050
uniprot id: Q8FPG7
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

196164:CE RS11445
gene id: 196164:CE_RS11445
uniprot id: Q8FN37
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

196164:CE RS13895
gene id: 196164:CE_RS13895
uniprot id: Q8FLQ2
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity.

196164:CE RS04540
gene id: 196164:CE_RS04540
uniprot id: Q8FR78
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

196164:CE RS13955
gene id: 196164:CE_RS13955
uniprot id: Q8FLN8
names: Function
names: Similarity
messages: Belongs to the TrhO family.
messages: Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs.

196164:CE RS08070
gene id: 196164:CE_RS08070
uniprot id: Q8FTE9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

196164:CE RS07520
gene id: 196164:CE_RS07520
uniprot id: Q8FTQ2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-3 family.
messages: Cytoplasm
messages: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.
messages: Monomer.

196164:CE RS14445
gene id: 196164:CE_RS14445
uniprot id: Q8FSV6
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

196164:CE RS04120
gene id: 196164:CE_RS04120
uniprot id: Q8FRF9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0182 family.
messages: Cell membrane

196164:CE RS07155
gene id: 196164:CE_RS07155
uniprot id: Q8FPR2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 1 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

196164:CE RS02920
gene id: 196164:CE_RS02920
uniprot id: Q8FS52
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

196164:CE RS13900
gene id: 196164:CE_RS13900
uniprot id: Q8FLQ0
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

196164:CE RS03245
gene id: 196164:CE_RS03245
uniprot id: Q8FRY8
names: Similarity
messages: Belongs to the UDPGP type 2 family.

196164:CE RS13585
gene id: 196164:CE_RS13585
uniprot id: Q8FLW3
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

196164:CE RS07215
gene id: 196164:CE_RS07215
uniprot id: Q8FPP9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

196164:CE RS06885
gene id: 196164:CE_RS06885
uniprot id: Q8FPW6
names: Similarity
messages: Belongs to the non-flavoprotein flavin reductase family.

196164:CE RS05185
gene id: 196164:CE_RS05185
uniprot id: Q8FQV2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

196164:CE RS11965
gene id: 196164:CE_RS11965
uniprot id: Q8FMT1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associates with subunits II, III and IV to form cytochrome c oxidase.
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Binds 1 copper B ion per subunit.
messages: Binds 2 heme groups per subunit.
messages: Cell membrane
messages: Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B (By similarity).

196164:CE RS10810
gene id: 196164:CE_RS10810
uniprot id: Q8FNG6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of glycine to tRNA(Gly).
messages: Cytoplasm
messages: Homodimer.

196164:CE RS11345
gene id: 196164:CE_RS11345
uniprot id: Q8FN57
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

196164:CE RS08800
gene id: 196164:CE_RS08800
uniprot id: Q8FPL0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

196164:CE RS13730
gene id: 196164:CE_RS13730
uniprot id: Q8FLT4
names: Function
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.
messages: Could possibly oxidize fatty acids using specific components.

196164:CE RS13300
gene id: 196164:CE_RS13300
uniprot id: Q8FM21
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0702 family.
messages: Cell membrane
messages: Membrane

196164:CE RS12225
gene id: 196164:CE_RS12225
uniprot id: Q8FMN7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

196164:CE RS12625
gene id: 196164:CE_RS12625
uniprot id: Q8FMF9
names: Similarity
messages: Belongs to the peptidase S13 family.

196164:CE RS00225
gene id: 196164:CE_RS00225
uniprot id: Q8FLF3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

196164:CE RS04660
gene id: 196164:CE_RS04660
uniprot id: Q8FR55
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

196164:CE RS11540
gene id: 196164:CE_RS11540
uniprot id: Q8FN15
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

196164:CE RS06420
gene id: 196164:CE_RS06420
uniprot id: Q8RQM6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

196164:CE RS01185
gene id: 196164:CE_RS01185
uniprot id: Q8FU34
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

196164:CE RS09620
gene id: 196164:CE_RS09620
uniprot id: Q8FP57
names: Similarity
messages: Belongs to the peptidase S1C family.

196164:CE RS11455
gene id: 196164:CE_RS11455
uniprot id: Q8FN35
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

196164:CE RS02655
gene id: 196164:CE_RS02655
uniprot id: Q8FSA0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

196164:CE RS09985
gene id: 196164:CE_RS09985
uniprot id: Q8FNY3
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

196164:CE RS08620
gene id: 196164:CE_RS08620
uniprot id: Q8FT40
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.

196164:CE RS08445
gene id: 196164:CE_RS08445
uniprot id: Q8FT75
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 2 subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

196164:CE RS03980
gene id: 196164:CE_RS03980
uniprot id: Q8FRI7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

196164:CE RS12635
gene id: 196164:CE_RS12635
uniprot id: Q8FMF7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the spermidine/spermine synthase family.
messages: Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
messages: Cell membrane
messages: Homodimer or homotetramer.

196164:CE RS10085
gene id: 196164:CE_RS10085
uniprot id: Q8FNW1
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

196164:CE RS00560
gene id: 196164:CE_RS00560
uniprot id: Q8FUG0
names: Similarity
messages: Belongs to the KdgT transporter family.

196164:CE RS07000
gene id: 196164:CE_RS07000
uniprot id: Q8FPU1
names: Subcellular Location Annotation
messages: Membrane

196164:CE RS03405
gene id: 196164:CE_RS03405
uniprot id: Q8FRV5
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 2 residues (Tyr-69 and Arg-72) present in a large hydrophobic pocket are probably involved in substrate specificity. They are important for desuccinylation activity, but dispensable for deacetylation activity.
messages: Belongs to the sirtuin family. Class III subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form.

196164:CE RS11060
gene id: 196164:CE_RS11060
uniprot id: Q8FNB6
names: Function
names: Similarity
messages: Belongs to the 2H phosphoesterase superfamily. ThpR family.
messages: Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'-phosphomonoester.

196164:CE RS04975
gene id: 196164:CE_RS04975
uniprot id: Q8FQZ6
names: Similarity
messages: Belongs to the transglycosylase family. Rpf subfamily.

196164:CE RS11765
gene id: 196164:CE_RS11765
uniprot id: Q8FMX2
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Uronate isomerase family.

196164:CE RS12600
gene id: 196164:CE_RS12600
uniprot id: Q8FMG4
names: Function
names: Similarity
messages: Belongs to the DHPS family.
messages: Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives.

196164:CE RS04470
gene id: 196164:CE_RS04470
uniprot id: Q8FR92
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. MalFG subfamily.
messages: Cell membrane
messages: Part of the ABC transporter complex MalEFGK involved in maltose/maltodextrin import. Probably responsible for the translocation of the substrate across the membrane.

196164:CE RS03540
gene id: 196164:CE_RS03540
uniprot id: Q8RQL9
names: Activity Regulation
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the monomeric-type IDH family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Monomer.
messages: Weakly inhibited by oxaloacetate, 2-oxoglutarate, and citrate. Severely inhibited by oxaloacetate plus glyoxylate (By similarity).

196164:CE RS07485
gene id: 196164:CE_RS07485
uniprot id: Q8FTR1
names: Similarity
messages: Belongs to the universal stress protein A family.

196164:CE RS01390
gene id: 196164:CE_RS01390
uniprot id: Q8FTZ8
names: Similarity
messages: Belongs to the catalase family.

196164:CE RS02620
gene id: 196164:CE_RS02620
uniprot id: Q8FSA8
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

196164:CE RS09345
gene id: 196164:CE_RS09345
uniprot id: Q8FPB3
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

196164:CE RS03885
gene id: 196164:CE_RS03885
uniprot id: Q8FRK7
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

196164:CE RS02465
gene id: 196164:CE_RS02465
uniprot id: Q8FSD6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the uroporphyrinogen decarboxylase family.
messages: Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
messages: Cytoplasm
messages: Homodimer.

196164:CE RS01370
gene id: 196164:CE_RS01370
uniprot id: Q8RQN1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartokinase family.
messages: Catalyzes the phosphorylation of the beta-carboxyl group of aspartic acid with ATP to yield 4-phospho-L-aspartate, which is involved in the branched biosynthetic pathway leading to the biosynthesis of amino acids lysine, threonine, isoleucine and methionine.
messages: Tetramer consisting of 2 isoforms Alpha (catalytic and regulation) and of a homodimer of 2 isoforms Beta (regulation).

196164:CE RS06785
gene id: 196164:CE_RS06785
uniprot id: Q8FPY4
names: Similarity
messages: Belongs to the shaker potassium channel beta subunit family.

196164:CE RS02630
gene id: 196164:CE_RS02630
uniprot id: Q8FSA5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

196164:CE RS10980
gene id: 196164:CE_RS10980
uniprot id: Q8FND2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the branched chain amino acid transporter family.
messages: Membrane

196164:CE RS01285
gene id: 196164:CE_RS01285
uniprot id: Q8FU18
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. GluQ subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5-dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon.

196164:CE RS03365
gene id: 196164:CE_RS03365
uniprot id: Q8FRW3
names: Similarity
messages: Belongs to the calycin superfamily. Lipocalin family.

196164:CE RS00180
gene id: 196164:CE_RS00180
uniprot id: Q8FLG3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VKOR family.
messages: Membrane

196164:CE RS05080
gene id: 196164:CE_RS05080
uniprot id: Q8FQX5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
messages: Cytoplasm
messages: Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

196164:CE RS04140
gene id: 196164:CE_RS04140
uniprot id: Q8FRF6
names: Similarity
messages: Belongs to the AccD/PCCB family.

196164:CE RS08595
gene id: 196164:CE_RS08595
uniprot id: Q8FT45
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

196164:CE RS09440
gene id: 196164:CE_RS09440
uniprot id: Q8FP93
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

196164:CE RS02965
gene id: 196164:CE_RS02965
uniprot id: Q8FS43
names: Function
messages: Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate.

196164:CE RS03640
gene id: 196164:CE_RS03640
uniprot id: Q8FRQ5
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
messages: Allosterically activated by GTP.
messages: Belongs to the UPRTase family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.
messages: Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.

196164:CE RS07190
gene id: 196164:CE_RS07190
uniprot id: Q8FPQ4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
messages: Cytoplasm
messages: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.

196164:CE RS12525
gene id: 196164:CE_RS12525
uniprot id: Q8FMH9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DisA family.
messages: Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c-di-AMP likely acts as a signaling molecule that may couple DNA integrity with a cellular process.
messages: Homooctamer.
messages: Participates in a DNA-damage check-point. DisA forms globular foci that rapidly scan along the chromosomes searching for lesions.

196164:CE RS09930
gene id: 196164:CE_RS09930
uniprot id: Q8FNZ5
names: Subcellular Location Annotation
messages: Membrane

196164:CE RS03920
gene id: 196164:CE_RS03920
uniprot id: Q8FRJ9
names: Similarity
messages: Belongs to the phosphohexose mutase family.

196164:CE RS08420
gene id: 196164:CE_RS08420
uniprot id: Q8FT80
names: Subcellular Location Annotation
messages: Membrane

196164:CE RS11440
gene id: 196164:CE_RS11440
uniprot id: Q8FN38
names: Subcellular Location Annotation
messages: Membrane

196164:CE RS06610
gene id: 196164:CE_RS06610
uniprot id: Q8FQ19
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

196164:CE RS02775
gene id: 196164:CE_RS02775
uniprot id: Q8FS79
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

196164:CE RS09885
gene id: 196164:CE_RS09885
uniprot id: Q8FP04
names: Similarity
names: Subunit
messages: Belongs to the pyruvate kinase family.
messages: Homotetramer.

196164:CE RS02735
gene id: 196164:CE_RS02735
uniprot id: Q8FS86
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

196164:CE RS13695
gene id: 196164:CE_RS13695
uniprot id: Q8FLU1
names: Subcellular Location Annotation
messages: Membrane

196164:CE RS00430
gene id: 196164:CE_RS00430
uniprot id: Q8FUI8
names: Subcellular Location Annotation
messages: Membrane

196164:CE RS01455
gene id: 196164:CE_RS01455
uniprot id: Q8FTY5
names: Subcellular Location Annotation
messages: Membrane

196164:CE RS03530
gene id: 196164:CE_RS03530
uniprot id: Q8FRS9
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

196164:CE RS08065
gene id: 196164:CE_RS08065
uniprot id: Q8FTF0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell membrane
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

196164:CE RS10200
gene id: 196164:CE_RS10200
uniprot id: Q8FNT8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

196164:CE RS09305
gene id: 196164:CE_RS09305
uniprot id: Q8RQM8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

196164:CE RS04895
gene id: 196164:CE_RS04895
uniprot id: Q8FR12
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

196164:CE RS03705
gene id: 196164:CE_RS03705
uniprot id: Q8FRP2
names: Function
names: Similarity
messages: Belongs to the isocitrate lyase/PEP mutase superfamily. Methylisocitrate lyase family.
messages: Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate.

196164:CE RS08390
gene id: 196164:CE_RS08390
uniprot id: Q8FT86
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

196164:CE RS06285
gene id: 196164:CE_RS06285
uniprot id: Q8FQ81
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

196164:CE RS01660
gene id: 196164:CE_RS01660
uniprot id: Q8FTU5
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

196164:CE RS09045
gene id: 196164:CE_RS09045
uniprot id: Q8FPG8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

196164:CE RS14160
gene id: 196164:CE_RS14160
uniprot id: Q8FLJ6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

196164:CE RS08575
gene id: 196164:CE_RS08575
uniprot id: Q8FT49
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

196164:CE RS10415
gene id: 196164:CE_RS10415
uniprot id: Q8FNP6
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

196164:CE RS07580
gene id: 196164:CE_RS07580
uniprot id: Q8FTP0
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

196164:CE RS07530
gene id: 196164:CE_RS07530
uniprot id: Q8FTQ0
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

196164:CE RS05770
gene id: 196164:CE_RS05770
uniprot id: Q8FQI3
names: Subcellular Location Annotation
messages: Membrane

196164:CE RS09525
gene id: 196164:CE_RS09525
uniprot id: Q8FP76
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

196164:CE RS03930
gene id: 196164:CE_RS03930
uniprot id: Q8FRJ7
names: Cofactor
names: Similarity
messages: Belongs to the mannose-6-phosphate isomerase type 1 family.
messages: Binds 1 zinc ion per subunit.

196164:CE RS03855
gene id: 196164:CE_RS03855
uniprot id: Q8FRL3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

196164:CE RS11910
gene id: 196164:CE_RS11910
uniprot id: Q8FMU3
names: Subcellular Location Annotation
messages: Membrane

196164:CE RS11395
gene id: 196164:CE_RS11395
uniprot id: Q8FN47
names: Similarity
messages: Belongs to the intradiol ring-cleavage dioxygenase family.

196164:CE RS08530
gene id: 196164:CE_RS08530
uniprot id: Q8FT58
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

196164:CE RS08665
gene id: 196164:CE_RS08665
uniprot id: Q8FT32
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

196164:CE RS02760
gene id: 196164:CE_RS02760
uniprot id: Q8FS81
names: Similarity
messages: Belongs to the acetyl-CoA hydrolase/transferase family.

196164:CE RS04725
gene id: 196164:CE_RS04725
uniprot id: Q8FR44
names: Similarity
messages: Belongs to the FPG family.

196164:CE RS07835
gene id: 196164:CE_RS07835
uniprot id: P59191
names: Similarity
messages: Belongs to the UPF0225 family.

196164:CE RS12720
gene id: 196164:CE_RS12720
uniprot id: Q8FMD9
names: Subcellular Location Annotation
messages: Membrane

196164:CE RS10665
gene id: 196164:CE_RS10665
uniprot id: Q8FNJ5
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: Acyl carrier protein involved in meromycolate extension.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

196164:CE RS12110
gene id: 196164:CE_RS12110
uniprot id: Q8FMQ6
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

196164:CE RS04985
gene id: 196164:CE_RS04985
uniprot id: Q8FQZ4
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.

196164:CE RS07200
gene id: 196164:CE_RS07200
uniprot id: Q8FPQ2
names: Similarity
messages: Belongs to the helicase family. RecG subfamily.

196164:CE RS06555
gene id: 196164:CE_RS06555
uniprot id: Q8FQ30
names: Caution
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

196164:CE RS05340
gene id: 196164:CE_RS05340
uniprot id: Q8FQS2
names: Function
names: Induction
messages: Repressed by DtxR under iron excess.
messages: Under iron limitation, represses the acn (aconitase), catA (catechol 1,2 dioxygenase), leuCD (isopropylmalate dehydratase), narKGHJI (nitrite/nitrate transporter and nitrate reductase), sdhCAB (succinate dehydrogenase), pta (phosphotransacetylase) and katA (catalase) genes.

196164:CE RS05390
gene id: 196164:CE_RS05390
uniprot id: Q8FQR2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic pantothenate kinase family.
messages: Cytoplasm

196164:CE RS07675
gene id: 196164:CE_RS07675
uniprot id: Q8FTM1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

196164:CE RS00825
gene id: 196164:CE_RS00825
uniprot id: Q8FUA5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

196164:CE RS08550
gene id: 196164:CE_RS08550
uniprot id: Q8FT54
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

196164:CE RS02125
gene id: 196164:CE_RS02125
uniprot id: Q8FSK5
names: Similarity
messages: Belongs to the short-chain fatty acyl-CoA assimilation regulator (ScfR) family.

196164:CE RS13200
gene id: 196164:CE_RS13200
uniprot id: Q8FM43
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BCCT transporter (TC 2.A.15) family.
messages: Membrane

196164:CE RS01740
gene id: 196164:CE_RS01740
uniprot id: Q8FST2
names: Subcellular Location Annotation
messages: Membrane

196164:CE RS03450
gene id: 196164:CE_RS03450
uniprot id: Q8FRU6
names: Subcellular Location Annotation
messages: Membrane

196164:CE RS02780
gene id: 196164:CE_RS02780
uniprot id: Q8FS78
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

196164:CE RS05170
gene id: 196164:CE_RS05170
uniprot id: Q8FQV6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

196164:CE RS11995
gene id: 196164:CE_RS11995
uniprot id: Q8FMS4
names: Function
names: Similarity
messages: Belongs to the glutaredoxin family.
messages: Electron transport system for the ribonucleotide reductase system NrdEF.

196164:CE RS06620
gene id: 196164:CE_RS06620
uniprot id: Q8FQ17
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NucS endonuclease family.
messages: Cleaves both 3' and 5' ssDNA extremities of branched DNA structures.
messages: Cytoplasm

196164:CE RS07715
gene id: 196164:CE_RS07715
uniprot id: Q8FTL6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.

196164:CE RS05055
gene id: 196164:CE_RS05055
uniprot id: Q8FQY0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class II aldolase/RraA-like family.
messages: Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2-oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions (By similarity).
messages: Divalent metal cation.
messages: Homotrimer.

196164:CE RS09360
gene id: 196164:CE_RS09360
uniprot id: Q8FPB0
names: Subcellular Location Annotation
messages: Membrane

196164:CE RS07435
gene id: 196164:CE_RS07435
uniprot id: Q8FTS7
names: Activity Regulation
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.
messages: Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.
messages: Belongs to the carbohydrate kinase pfkB family.
messages: Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate.

196164:CE RS13015
gene id: 196164:CE_RS13015
uniprot id: Q8FM78
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

196164:CE RS09180
gene id: 196164:CE_RS09180
uniprot id: Q8FPE0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Monomer.

196164:CE RS12780
gene id: 196164:CE_RS12780
uniprot id: Q8FMC7
names: Subcellular Location Annotation
messages: Membrane

196164:CE RS08095
gene id: 196164:CE_RS08095
uniprot id: Q8FTE4
names: Similarity
messages: Belongs to the Pup ligase/Pup deamidase family. Pup deamidase subfamily.

196164:CE RS05090
gene id: 196164:CE_RS05090
uniprot id: Q8FQX3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the urease beta subunit family.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

196164:CE RS08970
gene id: 196164:CE_RS08970
uniprot id: Q8FPI2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

196164:CE RS08135
gene id: 196164:CE_RS08135
uniprot id: Q8FTD6
names: Similarity
messages: Belongs to the class-II fumarase/aspartase family. Aspartase subfamily.

196164:CE RS08890
gene id: 196164:CE_RS08890
uniprot id: Q8FPJ2
names: Similarity
messages: Belongs to the DyP-type peroxidase family.

196164:CE RS02495
gene id: 196164:CE_RS02495
uniprot id: Q8FSD0
names: Subcellular Location Annotation
messages: Membrane

196164:CE RS03240
gene id: 196164:CE_RS03240
uniprot id: Q8FRY9
names: Subcellular Location Annotation
messages: Membrane

196164:CE RS05875
gene id: 196164:CE_RS05875
uniprot id: Q8FQF9
names: Cofactor
names: Function
messages: Binds 1 [3Fe-4S] cluster.
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

196164:CE RS09540
gene id: 196164:CE_RS09540
uniprot id: Q8FP71
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

196164:CE RS07500
gene id: 196164:CE_RS07500
uniprot id: Q8FTQ8
names: Subcellular Location Annotation
messages: Membrane

196164:CE RS11885
gene id: 196164:CE_RS11885
uniprot id: Q8FMU8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase PH family.
messages: Homohexameric ring arranged as a trimer of dimers.
messages: Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.

196164:CE RS11585
gene id: 196164:CE_RS11585
uniprot id: Q8CY23
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

196164:CE RS01180
gene id: 196164:CE_RS01180
uniprot id: Q8FU35
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MoaC family.
messages: Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
messages: Homohexamer; trimer of dimers.

196164:CE RS03130
gene id: 196164:CE_RS03130
uniprot id: Q8FS11
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAE transporter (TC 2.A.81) family.
messages: Cell membrane

196164:CE RS10235
gene id: 196164:CE_RS10235
uniprot id: Q8FNT1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MraZ family.
messages: Forms oligomers.
messages: nucleoid

196164:CE RS02395
gene id: 196164:CE_RS02395
uniprot id: Q8FSF0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the shikimate dehydrogenase family.
messages: Homodimer.
messages: Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids, and plays a key role in the quinate degradation pathway. Catalyzes the NAD(+)-dependent oxidation of both quinate and shikimate to 3-dehydroquinate and 3-dehydroshikimate, respectively. It can only use NAD.

196164:CE RS01835
gene id: 196164:CE_RS01835
uniprot id: Q8FSR5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

196164:CE RS02785
gene id: 196164:CE_RS02785
uniprot id: Q8FS77
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

196164:CE RS03755
gene id: 196164:CE_RS03755
uniprot id: Q8FRN4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

196164:CE RS08555
gene id: 196164:CE_RS08555
uniprot id: Q8FT53
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.

196164:CE RS09480
gene id: 196164:CE_RS09480
uniprot id: Q8FP85
names: Function
names: Similarity
messages: Belongs to the CobB/CobQ family. CobQ subfamily.
messages: Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation.