1913578:LPB140 RS09000
gene id: 1913578:LPB140_RS09000
uniprot id: A0A1L3JCM9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccA family.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

1913578:LPB140 RS08330
gene id: 1913578:LPB140_RS08330
uniprot id: A0A1L3JCC9
names: Function
messages: Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors. CheA is autophosphorylated; it can transfer its phosphate group to either CheB or CheY.

1913578:LPB140 RS03555
gene id: 1913578:LPB140_RS03555
uniprot id: A0A1L3JA90
names: Similarity
messages: Belongs to the sulfatase family.

1913578:LPB140 RS11480
gene id: 1913578:LPB140_RS11480
uniprot id: A0A1L3JFC5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1913578:LPB140 RS08425
gene id: 1913578:LPB140_RS08425
uniprot id: A0A1L3JCF4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

1913578:LPB140 RS11785
gene id: 1913578:LPB140_RS11785
uniprot id: A0A1L3JDZ2
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.

1913578:LPB140 RS05570
gene id: 1913578:LPB140_RS05570
uniprot id: A0A1L3JB50
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1913578:LPB140 RS07150
gene id: 1913578:LPB140_RS07150
uniprot id: A0A1L3JBT7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 30 kDa subunit family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1913578:LPB140 RS10155
gene id: 1913578:LPB140_RS10155
uniprot id: A0A1L3JF63
names: Similarity
messages: Belongs to the metallo-beta-lactamase superfamily. Class-B beta-lactamase family.

1913578:LPB140 RS03830
gene id: 1913578:LPB140_RS03830
uniprot id: A0A1L3JAD1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Membrane

1913578:LPB140 RS01745
gene id: 1913578:LPB140_RS01745
uniprot id: A0A1L3J9E3
names: Function
names: Similarity
messages: Belongs to the ParB family.
messages: Involved in chromosome partition. Localize to both poles of the predivisional cell following completion of DNA replication. Binds to the DNA origin of replication.

1913578:LPB140 RS02100
gene id: 1913578:LPB140_RS02100
uniprot id: A0A1L3J9N3
names: Similarity
messages: Belongs to the peptidase S8 family.

1913578:LPB140 RS08470
gene id: 1913578:LPB140_RS08470
uniprot id: A0A1L3JCF5
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.

1913578:LPB140 RS01700
gene id: 1913578:LPB140_RS01700
uniprot id: A0A1L3J9F9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the uroporphyrinogen decarboxylase family.
messages: Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1913578:LPB140 RS09730
gene id: 1913578:LPB140_RS09730
uniprot id: A0A1L3JD14
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

1913578:LPB140 RS02245
gene id: 1913578:LPB140_RS02245
uniprot id: A0A1L3J9P4
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1913578:LPB140 RS08270
gene id: 1913578:LPB140_RS08270
uniprot id: A0A1L3JF05
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1913578:LPB140 RS01735
gene id: 1913578:LPB140_RS01735
uniprot id: A0A1L3J9G6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the N7 position of guanine in position 527 of 16S rRNA.

1913578:LPB140 RS08315
gene id: 1913578:LPB140_RS08315
uniprot id: A0A1L3JCJ9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. SRP is a ribonucleoprotein composed of Ffh and a 4.5S RNA molecule.

1913578:LPB140 RS04030
gene id: 1913578:LPB140_RS04030
uniprot id: A0A1L3JAG1
names: Subcellular Location Annotation
messages: Membrane

1913578:LPB140 RS04590
gene id: 1913578:LPB140_RS04590
uniprot id: A0A1L3JEM2
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

1913578:LPB140 RS04465
gene id: 1913578:LPB140_RS04465
uniprot id: A0A1L3JAM9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1913578:LPB140 RS05125
gene id: 1913578:LPB140_RS05125
uniprot id: A0A1L3JB47
names: Similarity
messages: Belongs to the hcp beta-lactamase family.

1913578:LPB140 RS00070
gene id: 1913578:LPB140_RS00070
uniprot id: A0A1L3JE36
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

1913578:LPB140 RS01235
gene id: 1913578:LPB140_RS01235
uniprot id: A0A1L3J989
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.

1913578:LPB140 RS05725
gene id: 1913578:LPB140_RS05725
uniprot id: A0A1L3JB54
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 2 residues (Tyr-56 and Arg-59) present in a large hydrophobic pocket are probably involved in substrate specificity. They are important for desuccinylation activity, but dispensable for deacetylation activity.
messages: Belongs to the sirtuin family. Class III subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form.

1913578:LPB140 RS10570
gene id: 1913578:LPB140_RS10570
uniprot id: A0A1L3JDH4
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

1913578:LPB140 RS09270
gene id: 1913578:LPB140_RS09270
uniprot id: A0A1L3JCS8
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Inhibited by UTP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1913578:LPB140 RS09620
gene id: 1913578:LPB140_RS09620
uniprot id: A0A1L3JCY7
names: Similarity
messages: Belongs to the peptidase A24 family.

1913578:LPB140 RS02740
gene id: 1913578:LPB140_RS02740
uniprot id: A0A1L3J9X2
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Binds 1 copper ion per subunit, denoted as copper B.
messages: Binds 2 heme groups per subunit, denoted as high- and low-spin.
messages: Membrane

1913578:LPB140 RS09695
gene id: 1913578:LPB140_RS09695
uniprot id: A0A1L3JD01
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

1913578:LPB140 RS05215
gene id: 1913578:LPB140_RS05215
uniprot id: A0A1L3JAZ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

1913578:LPB140 RS04560
gene id: 1913578:LPB140_RS04560
uniprot id: A0A1L3JAN2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1913578:LPB140 RS02115
gene id: 1913578:LPB140_RS02115
uniprot id: A0A1L3J9R1
names: Similarity
messages: Belongs to the glutaredoxin family. Monothiol subfamily.

1913578:LPB140 RS02425
gene id: 1913578:LPB140_RS02425
uniprot id: A0A1L3J9Q6
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Catalyzes the phosphorylation of D-xylulose to D-xylulose 5-phosphate.

1913578:LPB140 RS04765
gene id: 1913578:LPB140_RS04765
uniprot id: A0A1L3JAZ2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S-adenosyl-L-methionine to the 2'-OH of the wobble nucleotide.

1913578:LPB140 RS02110
gene id: 1913578:LPB140_RS02110
uniprot id: A0A1L3J9K1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TerC family.
messages: Membrane

1913578:LPB140 RS09405
gene id: 1913578:LPB140_RS09405
uniprot id: A0A1L3JCW9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family. N-terminal subunit subfamily.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H. In this organism, the P 'protein' is a heterodimer of two subunits.

1913578:LPB140 RS06295
gene id: 1913578:LPB140_RS06295
uniprot id: A0A1L3JBD7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1913578:LPB140 RS05845
gene id: 1913578:LPB140_RS05845
uniprot id: A0A1L3JB85
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

1913578:LPB140 RS10430
gene id: 1913578:LPB140_RS10430
uniprot id: A0A1L3JDC8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

1913578:LPB140 RS10235
gene id: 1913578:LPB140_RS10235
uniprot id: A0A1L3JD91
names: Similarity
messages: Belongs to the pterin-4-alpha-carbinolamine dehydratase family.

1913578:LPB140 RS06465
gene id: 1913578:LPB140_RS06465
uniprot id: A0A1L3JEX8
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

1913578:LPB140 RS09510
gene id: 1913578:LPB140_RS09510
uniprot id: A0A1L3JD15
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

1913578:LPB140 RS07340
gene id: 1913578:LPB140_RS07340
uniprot id: A0A1L3JBV8
names: Similarity
messages: Belongs to the glutathione peroxidase family.

1913578:LPB140 RS02335
gene id: 1913578:LPB140_RS02335
uniprot id: A0A1L3J9R3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

1913578:LPB140 RS08235
gene id: 1913578:LPB140_RS08235
uniprot id: A0A1L3JCB0
names: Function
names: Similarity
messages: Belongs to the AMP nucleosidase family.
messages: Catalyzes the hydrolysis of the N-glycosidic bond of AMP to form adenine and ribose 5-phosphate. Involved in regulation of AMP concentrations.

1913578:LPB140 RS10210
gene id: 1913578:LPB140_RS10210
uniprot id: A0A1L3JD50
names: Similarity
messages: Belongs to the hcp beta-lactamase family.

1913578:LPB140 RS02615
gene id: 1913578:LPB140_RS02615
uniprot id: A0A1L3JEM3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

1913578:LPB140 RS02165
gene id: 1913578:LPB140_RS02165
uniprot id: A0A1L3J9P3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

1913578:LPB140 RS10720
gene id: 1913578:LPB140_RS10720
uniprot id: A0A1L3JDP8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.
messages: Cytoplasm
messages: Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.

1913578:LPB140 RS09130
gene id: 1913578:LPB140_RS09130
uniprot id: A0A1L3JCQ7
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1913578:LPB140 RS07210
gene id: 1913578:LPB140_RS07210
uniprot id: A0A1L3JBX6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Membrane

1913578:LPB140 RS08225
gene id: 1913578:LPB140_RS08225
uniprot id: A0A1L3JCB6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.
messages: Cytoplasm
messages: May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.

1913578:LPB140 RS00970
gene id: 1913578:LPB140_RS00970
uniprot id: A0A1L3J942
names: Subcellular Location Annotation
messages: Membrane

1913578:LPB140 RS05710
gene id: 1913578:LPB140_RS05710
uniprot id: A0A1L3JB66
names: Similarity
messages: Belongs to the GST superfamily.

1913578:LPB140 RS05625
gene id: 1913578:LPB140_RS05625
uniprot id: A0A1L3JB65
names: Similarity
messages: Belongs to the UPF0262 family.

1913578:LPB140 RS03155
gene id: 1913578:LPB140_RS03155
uniprot id: A0A1L3JEH0
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GSP I family.
messages: Cell inner membrane
messages: Cleaved by prepilin peptidase.
messages: Component of the type II secretion system required for the energy-dependent secretion of extracellular factors such as proteases and toxins from the periplasm.
messages: Membrane
messages: Type II secretion is composed of four main components: the outer membrane complex, the inner membrane complex, the cytoplasmic secretion ATPase and the periplasm-spanning pseudopilus.

1913578:LPB140 RS06350
gene id: 1913578:LPB140_RS06350
uniprot id: A0A1L3JF18
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

1913578:LPB140 RS07265
gene id: 1913578:LPB140_RS07265
uniprot id: A0A1L3JBY4
names: Similarity
messages: Belongs to the citrate synthase family.

1913578:LPB140 RS07280
gene id: 1913578:LPB140_RS07280
uniprot id: A0A1L3JBW3
names: Similarity
messages: Belongs to the TrpC family.

1913578:LPB140 RS07205
gene id: 1913578:LPB140_RS07205
uniprot id: A0A1L3JBU6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 5 family.
messages: Membrane
messages: Mitochondrion inner membrane

1913578:LPB140 RS02835
gene id: 1913578:LPB140_RS02835
uniprot id: A0A1L3JED5
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

1913578:LPB140 RS08180
gene id: 1913578:LPB140_RS08180
uniprot id: A0A1L3JCA5
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArgJ family.
messages: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.
messages: Cytoplasm
messages: Heterotetramer of two alpha and two beta chains.
messages: Some bacteria possess a monofunctional ArgJ, i.e., capable of catalyzing only the fifth step of the arginine biosynthetic pathway.

1913578:LPB140 RS09985
gene id: 1913578:LPB140_RS09985
uniprot id: A0A1L3JD56
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1913578:LPB140 RS10185
gene id: 1913578:LPB140_RS10185
uniprot id: A0A1L3JDG3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein uL14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein uL14 (rplN).

1913578:LPB140 RS02345
gene id: 1913578:LPB140_RS02345
uniprot id: A0A1L3J9P6
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1913578:LPB140 RS10425
gene id: 1913578:LPB140_RS10425
uniprot id: A0A1L3JDA8
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1913578:LPB140 RS08705
gene id: 1913578:LPB140_RS08705
uniprot id: A0A1L3JCI8
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.

1913578:LPB140 RS07105
gene id: 1913578:LPB140_RS07105
uniprot id: A0A1L3JBS6
names: Similarity
messages: Belongs to the transketolase family.

1913578:LPB140 RS06050
gene id: 1913578:LPB140_RS06050
uniprot id: A0A1L3JBI8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1913578:LPB140 RS10020
gene id: 1913578:LPB140_RS10020
uniprot id: A0A1L3JD20
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane
messages: Membrane

1913578:LPB140 RS08730
gene id: 1913578:LPB140_RS08730
uniprot id: A0A1L3JCK1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M17 family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm
messages: Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.

1913578:LPB140 RS07800
gene id: 1913578:LPB140_RS07800
uniprot id: A0A1L3JC56
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2B subfamily.
messages: Cytoplasm
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1913578:LPB140 RS00040
gene id: 1913578:LPB140_RS00040
uniprot id: A0A1L3JE49
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm

1913578:LPB140 RS05855
gene id: 1913578:LPB140_RS05855
uniprot id: A0A1L3JBF8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0161 family.
messages: Cell membrane
messages: Could be involved in insertion of integral membrane proteins into the membrane.

1913578:LPB140 RS08660
gene id: 1913578:LPB140_RS08660
uniprot id: A0A1L3JCJ4
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family. GreB subfamily.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length.

1913578:LPB140 RS02460
gene id: 1913578:LPB140_RS02460
uniprot id: A0A1L3J9W7
names: Similarity
messages: Belongs to the FBPase class 2 family.

1913578:LPB140 RS06780
gene id: 1913578:LPB140_RS06780
uniprot id: A0A1L3JBQ3
names: Similarity
messages: Belongs to the GST superfamily. Zeta family.

1913578:LPB140 RS02490
gene id: 1913578:LPB140_RS02490
uniprot id: A0A1L3J9S7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

1913578:LPB140 RS10115
gene id: 1913578:LPB140_RS10115
uniprot id: A0A1L3JDD9
names: Similarity
messages: Belongs to the biopterin-dependent aromatic amino acid hydroxylase family.

1913578:LPB140 RS02325
gene id: 1913578:LPB140_RS02325
uniprot id: A0A1L3J9U3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

1913578:LPB140 RS01925
gene id: 1913578:LPB140_RS01925
uniprot id: A0A1L3J9M7
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

1913578:LPB140 RS06330
gene id: 1913578:LPB140_RS06330
uniprot id: A0A1L3JBF1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

1913578:LPB140 RS01525
gene id: 1913578:LPB140_RS01525
uniprot id: A0A1L3J9B3
names: Function
messages: Acts on leucine, isoleucine and valine.

1913578:LPB140 RS08060
gene id: 1913578:LPB140_RS08060
uniprot id: A0A1L3JC96
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

1913578:LPB140 RS11615
gene id: 1913578:LPB140_RS11615
uniprot id: A0A1L3JE34
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

1913578:LPB140 RS06455
gene id: 1913578:LPB140_RS06455
uniprot id: A0A1L3JBH4
names: Similarity
messages: Belongs to the short-chain fatty acyl-CoA assimilation regulator (ScfR) family.

1913578:LPB140 RS02695
gene id: 1913578:LPB140_RS02695
uniprot id: A0A1L3J9X0
names: Similarity
messages: Belongs to the threonine synthase family.

1913578:LPB140 RS08320
gene id: 1913578:LPB140_RS08320
uniprot id: A0A1L3JCC8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YciB family.
messages: Cell inner membrane
messages: Plays a role in cell envelope biogenesis, maintenance of cell envelope integrity and membrane homeostasis.

1913578:LPB140 RS02845
gene id: 1913578:LPB140_RS02845
uniprot id: A0A1L3J9X6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HsdR family.
messages: Subunit R is required for both nuclease and ATPase activities, but not for modification.
messages: The type I restriction/modification system is composed of three polypeptides R, M and S.

1913578:LPB140 RS07110
gene id: 1913578:LPB140_RS07110
uniprot id: A0A1L3JBS4
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

1913578:LPB140 RS11000
gene id: 1913578:LPB140_RS11000
uniprot id: A0A1L3JDT7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the R-transferase family. Bpt subfamily.
messages: Cytoplasm
messages: Functions in the N-end rule pathway of protein degradation where it conjugates Leu from its aminoacyl-tRNA to the N-termini of proteins containing an N-terminal aspartate or glutamate.

1913578:LPB140 RS03080
gene id: 1913578:LPB140_RS03080
uniprot id: A0A1L3JA12
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

1913578:LPB140 RS11075
gene id: 1913578:LPB140_RS11075
uniprot id: A0A1L3JDN2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1913578:LPB140 RS10670
gene id: 1913578:LPB140_RS10670
uniprot id: A0A1L3JDG5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YhdE subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

1913578:LPB140 RS06755
gene id: 1913578:LPB140_RS06755
uniprot id: A0A1L3JBK4
names: Similarity
messages: Belongs to the AlaDH/PNT family.

1913578:LPB140 RS02025
gene id: 1913578:LPB140_RS02025
uniprot id: A0A1L3JEC0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1913578:LPB140 RS04935
gene id: 1913578:LPB140_RS04935
uniprot id: A0A1L3JAT5
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1913578:LPB140 RS03860
gene id: 1913578:LPB140_RS03860
uniprot id: A0A1L3JAC4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Cell membrane
messages: Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.
messages: Membrane

1913578:LPB140 RS05575
gene id: 1913578:LPB140_RS05575
uniprot id: A0A1L3JER8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SurE nucleotidase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Cytoplasm
messages: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.

1913578:LPB140 RS07910
gene id: 1913578:LPB140_RS07910
uniprot id: A0A1L3JF24
names: Subcellular Location Annotation
messages: Endoplasmic reticulum
messages: Golgi apparatus
messages: Lysosome

1913578:LPB140 RS01020
gene id: 1913578:LPB140_RS01020
uniprot id: A0A1L3J981
names: Similarity
messages: Belongs to the PrpD family.

1913578:LPB140 RS00795
gene id: 1913578:LPB140_RS00795
uniprot id: A0A1L3J924
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

1913578:LPB140 RS08790
gene id: 1913578:LPB140_RS08790
uniprot id: A0A1L3JF08
names: Function
messages: Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Seems to participate in the biosynthesis of the nitrogenase metalloclusters by providing the inorganic sulfur required for the Fe-S core formation.

1913578:LPB140 RS07785
gene id: 1913578:LPB140_RS07785
uniprot id: A0A1L3JC70
names: Function
names: Similarity
messages: Belongs to the peptidase S11 family.
messages: Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors.

1913578:LPB140 RS03400
gene id: 1913578:LPB140_RS03400
uniprot id: A0A1L3JA55
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

1913578:LPB140 RS04800
gene id: 1913578:LPB140_RS04800
uniprot id: A0A1L3JAS0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

1913578:LPB140 RS09090
gene id: 1913578:LPB140_RS09090
uniprot id: A0A1L3JCP6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

1913578:LPB140 RS02995
gene id: 1913578:LPB140_RS02995
uniprot id: A0A1L3J9Z7
names: Similarity
messages: Belongs to the sterol desaturase family.

1913578:LPB140 RS06395
gene id: 1913578:LPB140_RS06395
uniprot id: A0A1L3JBJ9
names: Subcellular Location Annotation
messages: Membrane

1913578:LPB140 RS11505
gene id: 1913578:LPB140_RS11505
uniprot id: A0A1L3JDT5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecX family.
messages: Cytoplasm

1913578:LPB140 RS11605
gene id: 1913578:LPB140_RS11605
uniprot id: A0A1L3JDT9
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis. Some bacteria have evolved a zinc-coordinating structure that stabilizes the LID domain.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1913578:LPB140 RS09820
gene id: 1913578:LPB140_RS09820
uniprot id: A0A1L3JD22
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase delta chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

1913578:LPB140 RS04885
gene id: 1913578:LPB140_RS04885
uniprot id: A0A1L3JEW2
names: Similarity
messages: Belongs to the peptidase S9A family.

1913578:LPB140 RS02595
gene id: 1913578:LPB140_RS02595
uniprot id: A0A1L3J9V0
names: Domain
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 dependent methionine synthase family.
messages: Catalyzes the transfer of a methyl group from methyl-cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
messages: Modular enzyme with four functionally distinct domains. The isolated Hcy-binding domain catalyzes methyl transfer from free methylcobalamin to homocysteine. The Hcy-binding domain in association with the pterin-binding domain catalyzes the methylation of cob(I)alamin by methyltetrahydrofolate and the methylation of homocysteine. The B12-binding domain binds the cofactor. The AdoMet activation domain binds S-adenosyl-L-methionine. Under aerobic conditions cob(I)alamin can be converted to inactive cob(II)alamin. Reductive methylation by S-adenosyl-L-methionine and flavodoxin regenerates methylcobalamin.

1913578:LPB140 RS11060
gene id: 1913578:LPB140_RS11060
uniprot id: A0A1L3JDU9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

1913578:LPB140 RS08645
gene id: 1913578:LPB140_RS08645
uniprot id: A0A1L3JCI5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

1913578:LPB140 RS06360
gene id: 1913578:LPB140_RS06360
uniprot id: A0A1L3JBH0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

1913578:LPB140 RS10160
gene id: 1913578:LPB140_RS10160
uniprot id: A0A1L3JD74
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

1913578:LPB140 RS02215
gene id: 1913578:LPB140_RS02215
uniprot id: A0A1L3J9N2
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1913578:LPB140 RS00545
gene id: 1913578:LPB140_RS00545
uniprot id: A0A1L3J8Z2
names: Similarity
messages: Belongs to the RecJ family.

1913578:LPB140 RS03270
gene id: 1913578:LPB140_RS03270
uniprot id: A0A1L3JEF7
names: Subcellular Location Annotation
messages: Membrane

1913578:LPB140 RS09335
gene id: 1913578:LPB140_RS09335
uniprot id: A0A1L3JCV1
names: Cofactor
names: Similarity
messages: Belongs to the nitroreductase family.
messages: Binds 1 FMN per subunit.

1913578:LPB140 RS10245
gene id: 1913578:LPB140_RS10245
uniprot id: A0A1L3JD88
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmB/CycW/HelB family.
messages: Cell inner membrane
messages: Membrane
messages: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.

1913578:LPB140 RS03470
gene id: 1913578:LPB140_RS03470
uniprot id: A0A1L3JA63
names: Function
names: PTM
names: Similarity
messages: Acetylated. Deacetylation by the SIR2-homolog deacetylase activates the enzyme.
messages: Belongs to the ATP-dependent AMP-binding enzyme family.
messages: Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.

1913578:LPB140 RS06880
gene id: 1913578:LPB140_RS06880
uniprot id: A0A1L3JEW9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1913578:LPB140 RS06795
gene id: 1913578:LPB140_RS06795
uniprot id: A0A1L3JBM7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccD/PCCB family.
messages: Binds 1 zinc ion per subunit.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

1913578:LPB140 RS09805
gene id: 1913578:LPB140_RS09805
uniprot id: A0A1L3JD18
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.

1913578:LPB140 RS04640
gene id: 1913578:LPB140_RS04640
uniprot id: A0A1L3JAP6
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1913578:LPB140 RS10230
gene id: 1913578:LPB140_RS10230
uniprot id: A0A1L3JD71
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1913578:LPB140 RS06370
gene id: 1913578:LPB140_RS06370
uniprot id: A0A1L3JET7
names: Function
names: Similarity
messages: Belongs to the HrcA family.
messages: Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons.

1913578:LPB140 RS00780
gene id: 1913578:LPB140_RS00780
uniprot id: A0A1L3J919
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

1913578:LPB140 RS10145
gene id: 1913578:LPB140_RS10145
uniprot id: A0A1L3JD40
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

1913578:LPB140 RS11700
gene id: 1913578:LPB140_RS11700
uniprot id: A0A1L3JE00
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

1913578:LPB140 RS00870
gene id: 1913578:LPB140_RS00870
uniprot id: A0A1L3J926
names: Similarity
messages: Belongs to the LOG family.

1913578:LPB140 RS08405
gene id: 1913578:LPB140_RS08405
uniprot id: A0A1L3JCE1
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

1913578:LPB140 RS02385
gene id: 1913578:LPB140_RS02385
uniprot id: A0A1L3JEE2
names: Similarity
messages: Belongs to the RNase T2 family.

1913578:LPB140 RS07650
gene id: 1913578:LPB140_RS07650
uniprot id: A0A1L3JC04
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 1 lipoyl cofactor covalently.
messages: Forms a 24-polypeptide structural core with octahedral symmetry.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).

1913578:LPB140 RS03840
gene id: 1913578:LPB140_RS03840
uniprot id: A0A1L3JAJ0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PNP synthase family.
messages: Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.
messages: Cytoplasm
messages: Homooctamer; tetramer of dimers.

1913578:LPB140 RS04220
gene id: 1913578:LPB140_RS04220
uniprot id: A0A1L3JAJ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

1913578:LPB140 RS08870
gene id: 1913578:LPB140_RS08870
uniprot id: A0A1L3JCK9
names: Function
names: Similarity
messages: Belongs to the HPPK family.
messages: Catalyzes the transfer of pyrophosphate from adenosine triphosphate (ATP) to 6-hydroxymethyl-7,8-dihydropterin, an enzymatic step in folate biosynthesis pathway.

1913578:LPB140 RS08025
gene id: 1913578:LPB140_RS08025
uniprot id: A0A1L3JC79
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

1913578:LPB140 RS04860
gene id: 1913578:LPB140_RS04860
uniprot id: A0A1L3JAS9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the malate synthase family. GlcB subfamily.
messages: Cytoplasm
messages: Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1913578:LPB140 RS02255
gene id: 1913578:LPB140_RS02255
uniprot id: A0A1L3JEC7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

1913578:LPB140 RS09490
gene id: 1913578:LPB140_RS09490
uniprot id: A0A1L3JCW6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1913578:LPB140 RS00365
gene id: 1913578:LPB140_RS00365
uniprot id: A0A1L3J8W1
names: Similarity
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.

1913578:LPB140 RS04955
gene id: 1913578:LPB140_RS04955
uniprot id: A0A1L3JB16
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
messages: Cytoplasm
messages: Homotrimer.
messages: In the C-terminal section; belongs to the transferase hexapeptide repeat family.
messages: In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1913578:LPB140 RS05805
gene id: 1913578:LPB140_RS05805
uniprot id: A0A1L3JB68
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm
messages: Homodimer.

1913578:LPB140 RS08515
gene id: 1913578:LPB140_RS08515
uniprot id: A0A1L3JCG0
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

1913578:LPB140 RS02190
gene id: 1913578:LPB140_RS02190
uniprot id: A0A1L3J9N4
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1913578:LPB140 RS03930
gene id: 1913578:LPB140_RS03930
uniprot id: A0A1L3JAE0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE. Acts before DnaK, in the processing of protein aggregates. Protein binding stimulates the ATPase activity; ATP hydrolysis unfolds the denatured protein aggregates, which probably helps expose new hydrophobic binding sites on the surface of ClpB-bound aggregates, contributing to the solubilization and refolding of denatured protein aggregates by DnaK.

1913578:LPB140 RS07120
gene id: 1913578:LPB140_RS07120
uniprot id: A0A1L3JBZ2
names: Similarity
messages: Belongs to the class I fructose-bisphosphate aldolase family.

1913578:LPB140 RS05510
gene id: 1913578:LPB140_RS05510
uniprot id: A0A1L3JB53
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1913578:LPB140 RS05960
gene id: 1913578:LPB140_RS05960
uniprot id: A0A1L3JES1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase E/G family. RNase E subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per homotetramer.
messages: Cell inner membrane
messages: Cytoplasm
messages: Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs.
messages: Homotetramer formed by a dimer of dimers.

1913578:LPB140 RS01795
gene id: 1913578:LPB140_RS01795
uniprot id: A0A1L3J9G5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.

1913578:LPB140 RS07420
gene id: 1913578:LPB140_RS07420
uniprot id: A0A1L3JBY6
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family.

1913578:LPB140 RS05635
gene id: 1913578:LPB140_RS05635
uniprot id: A0A1L3JB62
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAPS reductase family. CysH subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of sulfite from adenosine 5'-phosphosulfate (APS) using thioredoxin as an electron donor.
messages: Cytoplasm

1913578:LPB140 RS06855
gene id: 1913578:LPB140_RS06855
uniprot id: A0A1L3JBP2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Membrane

1913578:LPB140 RS09225
gene id: 1913578:LPB140_RS09225
uniprot id: A0A1L3JCT1
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds the 23S rRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of the 50S ribosomal subunit.

1913578:LPB140 RS06815
gene id: 1913578:LPB140_RS06815
uniprot id: A0A1L3JBL7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the OMP decarboxylase family. Type 1 subfamily.
messages: Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
messages: Homodimer.

1913578:LPB140 RS00505
gene id: 1913578:LPB140_RS00505
uniprot id: A0A1L3J8Z3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1913578:LPB140 RS10270
gene id: 1913578:LPB140_RS10270
uniprot id: A0A1L3JFE7
names: Similarity
messages: Belongs to the peptidase M17 family.

1913578:LPB140 RS00530
gene id: 1913578:LPB140_RS00530
uniprot id: A0A1L3J8Y7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MoaE family.
messages: Converts molybdopterin precursor Z into molybdopterin. This requires the incorporation of two sulfur atoms into precursor Z to generate a dithiolene group. The sulfur is provided by MoaD.
messages: Heterotetramer of 2 MoaD subunits and 2 MoaE subunits. Also stable as homodimer. The enzyme changes between these two forms during catalysis.

1913578:LPB140 RS01960
gene id: 1913578:LPB140_RS01960
uniprot id: A0A1L3J9K6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: Homodimer.

1913578:LPB140 RS06910
gene id: 1913578:LPB140_RS06910
uniprot id: A0A1L3JBQ2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family. ParE type 1 subfamily.
messages: Heterotetramer composed of ParC and ParE.
messages: Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.

1913578:LPB140 RS02150
gene id: 1913578:LPB140_RS02150
uniprot id: A0A1L3J9M8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1913578:LPB140 RS04920
gene id: 1913578:LPB140_RS04920
uniprot id: A0A1L3JAT9
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1913578:LPB140 RS11640
gene id: 1913578:LPB140_RS11640
uniprot id: A0A1L3JDU4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

1913578:LPB140 RS00940
gene id: 1913578:LPB140_RS00940
uniprot id: A0A1L3J928
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1913578:LPB140 RS02340
gene id: 1913578:LPB140_RS02340
uniprot id: A0A1L3J9Q4
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

1913578:LPB140 RS11460
gene id: 1913578:LPB140_RS11460
uniprot id: A0A1L3JDV8
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Homooctamer.

1913578:LPB140 RS05915
gene id: 1913578:LPB140_RS05915
uniprot id: A0A1L3JBG8
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

1913578:LPB140 RS10735
gene id: 1913578:LPB140_RS10735
uniprot id: A0A1L3JFF8
names: Subcellular Location Annotation
messages: Membrane

1913578:LPB140 RS05595
gene id: 1913578:LPB140_RS05595
uniprot id: A0A1L3JB41
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methylthiotransferase family. RimO subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein uS12.
messages: Cytoplasm

1913578:LPB140 RS11885
gene id: 1913578:LPB140_RS11885
uniprot id: A0A1L3JE09
names: Subcellular Location Annotation
messages: Membrane

1913578:LPB140 RS00685
gene id: 1913578:LPB140_RS00685
uniprot id: A0A1L3J933
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

1913578:LPB140 RS05445
gene id: 1913578:LPB140_RS05445
uniprot id: A0A1L3JB28
names: Subcellular Location Annotation
messages: Membrane

1913578:LPB140 RS05530
gene id: 1913578:LPB140_RS05530
uniprot id: A0A1L3JB99
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1913578:LPB140 RS11690
gene id: 1913578:LPB140_RS11690
uniprot id: A0A1L3JDV5
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

1913578:LPB140 RS01305
gene id: 1913578:LPB140_RS01305
uniprot id: A0A1L3J9A2
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1913578:LPB140 RS06770
gene id: 1913578:LPB140_RS06770
uniprot id: A0A1L3JBK3
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.

1913578:LPB140 RS09535
gene id: 1913578:LPB140_RS09535
uniprot id: A0A1L3JCX8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1913578:LPB140 RS10870
gene id: 1913578:LPB140_RS10870
uniprot id: A0A1L3JDJ3
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

1913578:LPB140 RS04875
gene id: 1913578:LPB140_RS04875
uniprot id: A0A1L3JAR9
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

1913578:LPB140 RS09275
gene id: 1913578:LPB140_RS09275
uniprot id: A0A1L3JCX2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

1913578:LPB140 RS11725
gene id: 1913578:LPB140_RS11725
uniprot id: A0A1L3JDX8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

1913578:LPB140 RS08675
gene id: 1913578:LPB140_RS08675
uniprot id: A0A1L3JCH8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase D family.
messages: Cytoplasm
messages: Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides.

1913578:LPB140 RS10875
gene id: 1913578:LPB140_RS10875
uniprot id: A0A1L3JDK2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

1913578:LPB140 RS07195
gene id: 1913578:LPB140_RS07195
uniprot id: A0A1L3JBU2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 6 family.
messages: Cell membrane
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1913578:LPB140 RS01135
gene id: 1913578:LPB140_RS01135
uniprot id: A0A1L3J959
names: Similarity
messages: Belongs to the HMG-CoA lyase family.

1913578:LPB140 RS12460
gene id: 1913578:LPB140_RS12460
uniprot id: A0A1L3JF61
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

1913578:LPB140 RS08215
gene id: 1913578:LPB140_RS08215
uniprot id: A0A1L3JCB2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm

1913578:LPB140 RS01860
gene id: 1913578:LPB140_RS01860
uniprot id: A0A1L3J9I8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

1913578:LPB140 RS03035
gene id: 1913578:LPB140_RS03035
uniprot id: A0A1L3JEG0
names: Similarity
messages: Belongs to the AlaDH/PNT family.

1913578:LPB140 RS01565
gene id: 1913578:LPB140_RS01565
uniprot id: A0A1L3J9D6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily.
messages: Cell inner membrane
messages: Involved in the import of queuosine (Q) precursors, required for Q precursor salvage.

1913578:LPB140 RS04135
gene id: 1913578:LPB140_RS04135
uniprot id: A0A1L3JAH1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1913578:LPB140 RS01355
gene id: 1913578:LPB140_RS01355
uniprot id: A0A1L3J9B2
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Binds two Mg(2+) per subunit. The magnesium ions form salt bridges with both the protein and the DNA. Can also accept other divalent metal cations, such as Mn(2+) or Ca(2+).
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

1913578:LPB140 RS04530
gene id: 1913578:LPB140_RS04530
uniprot id: A0A1L3JAP5
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

1913578:LPB140 RS06810
gene id: 1913578:LPB140_RS06810
uniprot id: A0A1L3JBL3
names: Similarity
messages: Belongs to the TrpF family.

1913578:LPB140 RS04155
gene id: 1913578:LPB140_RS04155
uniprot id: A0A1L3JAI2
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1913578:LPB140 RS07970
gene id: 1913578:LPB140_RS07970
uniprot id: A0A1L3JC77
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

1913578:LPB140 RS06315
gene id: 1913578:LPB140_RS06315
uniprot id: A0A1L3JET1
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

1913578:LPB140 RS03920
gene id: 1913578:LPB140_RS03920
uniprot id: A0A1L3JAD6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TspO/BZRP family.
messages: Membrane

1913578:LPB140 RS08500
gene id: 1913578:LPB140_RS08500
uniprot id: A0A1L3JF00
names: Function
names: Similarity
messages: Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage.
messages: Belongs to the Nudix hydrolase family. RppH subfamily.

1913578:LPB140 RS10150
gene id: 1913578:LPB140_RS10150
uniprot id: A0A1L3JF85
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1913578:LPB140 RS04990
gene id: 1913578:LPB140_RS04990
uniprot id: A0A1L3JAU5
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: May also have succinyldiaminopimelate aminotransferase activity, thus carrying out the corresponding step in lysine biosynthesis.

1913578:LPB140 RS11645
gene id: 1913578:LPB140_RS11645
uniprot id: A0A1L3JDU7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

1913578:LPB140 RS07125
gene id: 1913578:LPB140_RS07125
uniprot id: A0A1L3JBS0
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1913578:LPB140 RS10055
gene id: 1913578:LPB140_RS10055
uniprot id: A0A1L3JDC9
names: Caution
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the peroxidase family. Peroxidase/catalase subfamily.
messages: Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per dimer.
messages: Formation of the three residue Trp-Tyr-Met cross-link is important for the catalase, but not the peroxidase activity of the enzyme.
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1913578:LPB140 RS08145
gene id: 1913578:LPB140_RS08145
uniprot id: A0A1L3JF34
names: Similarity
messages: Belongs to the SdhE FAD assembly factor family.

1913578:LPB140 RS03755
gene id: 1913578:LPB140_RS03755
uniprot id: A0A1L3JAC5
names: Similarity
messages: Belongs to the GARS family.

1913578:LPB140 RS10915
gene id: 1913578:LPB140_RS10915
uniprot id: A0A1L3JFG8
names: Similarity
messages: Belongs to the TlyA family.

1913578:LPB140 RS08375
gene id: 1913578:LPB140_RS08375
uniprot id: A0A1L3JCK4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

1913578:LPB140 RS11415
gene id: 1913578:LPB140_RS11415
uniprot id: A0A1L3JDT0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

1913578:LPB140 RS07635
gene id: 1913578:LPB140_RS07635
uniprot id: A0A1L3JC10
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 3 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).
messages: Consists of three domains: the N-terminal catalytic domain, the anticodon-binding domain and the C-terminal extension.
messages: Cytoplasm
messages: Homodimer.

1913578:LPB140 RS04780
gene id: 1913578:LPB140_RS04780
uniprot id: A0A1L3JAR5
names: Cofactor
messages: Binds 1 heme c group covalently per subunit.

1913578:LPB140 RS05295
gene id: 1913578:LPB140_RS05295
uniprot id: A0A1L3JB07
names: Activity Regulation
names: Caution
names: Domain
names: Function
names: Similarity
messages: Belongs to the GlnD family.
messages: Has four distinct domains: an N-terminal nucleotidyltransferase (NT) domain responsible for UTase activity, a central HD domain that encodes UR activity, and two C-terminal ACT domains that seem to have a role in glutamine sensing.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen metabolism.
messages: Uridylyltransferase (UTase) activity is inhibited by glutamine, while glutamine activates uridylyl-removing (UR) activity.

1913578:LPB140 RS01275
gene id: 1913578:LPB140_RS01275
uniprot id: A0A1L3J9A7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

1913578:LPB140 RS05310
gene id: 1913578:LPB140_RS05310
uniprot id: A0A1L3JAZ6
names: Subcellular Location Annotation
messages: Mitochondrion

1913578:LPB140 RS08465
gene id: 1913578:LPB140_RS08465
uniprot id: A0A1L3JF20
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PRA-CH family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.
messages: Cytoplasm
messages: Homodimer.

1913578:LPB140 RS02830
gene id: 1913578:LPB140_RS02830
uniprot id: A0A1L3J9Y0
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit B family.

1913578:LPB140 RS00990
gene id: 1913578:LPB140_RS00990
uniprot id: A0A1L3JE64
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1913578:LPB140 RS10255
gene id: 1913578:LPB140_RS10255
uniprot id: A0A1L3JD87
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

1913578:LPB140 RS04915
gene id: 1913578:LPB140_RS04915
uniprot id: A0A1L3JAU6
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1913578:LPB140 RS10700
gene id: 1913578:LPB140_RS10700
uniprot id: A0A1L3JDE5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the H(+)-translocating pyrophosphatase (TC 3.A.10) family. K(+)-insensitive subfamily.
messages: Cell membrane
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force.

1913578:LPB140 RS05150
gene id: 1913578:LPB140_RS05150
uniprot id: A0A1L3JAY9
names: Similarity
messages: Belongs to the adrenodoxin/putidaredoxin family.

1913578:LPB140 RS05160
gene id: 1913578:LPB140_RS05160
uniprot id: A0A1L3JAX9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family.
messages: Membrane

1913578:LPB140 RS07440
gene id: 1913578:LPB140_RS07440
uniprot id: A0A1L3JBZ0
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.

1913578:LPB140 RS11760
gene id: 1913578:LPB140_RS11760
uniprot id: A0A1L3JFD7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1913578:LPB140 RS09120
gene id: 1913578:LPB140_RS09120
uniprot id: A0A1L3JCR0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

1913578:LPB140 RS00845
gene id: 1913578:LPB140_RS00845
uniprot id: A0A1L3JE75
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.
messages: Binds 1 S-adenosyl-L-methionine per subunit.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1913578:LPB140 RS07495
gene id: 1913578:LPB140_RS07495
uniprot id: A0A1L3JBZ1
names: Similarity
messages: Belongs to the methylmalonyl-CoA epimerase family.

1913578:LPB140 RS04125
gene id: 1913578:LPB140_RS04125
uniprot id: A0A1L3JAG5
names: Function
names: Similarity
messages: Belongs to the mannonate dehydratase family.
messages: Catalyzes the dehydration of D-mannonate.

1913578:LPB140 RS02470
gene id: 1913578:LPB140_RS02470
uniprot id: A0A1L3J9S4
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

1913578:LPB140 RS05850
gene id: 1913578:LPB140_RS05850
uniprot id: A0A1L3JB86
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Cell membrane
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

1913578:LPB140 RS07185
gene id: 1913578:LPB140_RS07185
uniprot id: A0A1L3JBT1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 1 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.

1913578:LPB140 RS03120
gene id: 1913578:LPB140_RS03120
uniprot id: A0A1L3JA11
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1913578:LPB140 RS09375
gene id: 1913578:LPB140_RS09375
uniprot id: A0A1L3JCV4
names: Similarity
messages: Belongs to the PAPS reductase family. CysD subfamily.

1913578:LPB140 RS04455
gene id: 1913578:LPB140_RS04455
uniprot id: A0A1L3JEM7
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1913578:LPB140 RS02000
gene id: 1913578:LPB140_RS02000
uniprot id: A0A1L3J9J6
names: Cofactor
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.
messages: Binds 1 FAD per dimer.

1913578:LPB140 RS07180
gene id: 1913578:LPB140_RS07180
uniprot id: A0A1L3JC02
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the complex I 75 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1913578:LPB140 RS09665
gene id: 1913578:LPB140_RS09665
uniprot id: A0A1L3JCZ6
names: Cofactor
names: Similarity
messages: Belongs to the 4HPPD family.
messages: Binds 1 Fe cation per subunit.

1913578:LPB140 RS07170
gene id: 1913578:LPB140_RS07170
uniprot id: A0A1L3JEZ2
names: Function
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.

1913578:LPB140 RS06820
gene id: 1913578:LPB140_RS06820
uniprot id: A0A1L3JBM9
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.

1913578:LPB140 RS02935
gene id: 1913578:LPB140_RS02935
uniprot id: A0A1L3J9Z8
names: Function
names: Similarity
messages: Belongs to the LDH/MDH superfamily. MDH type 3 family.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.

1913578:LPB140 RS07285
gene id: 1913578:LPB140_RS07285
uniprot id: A0A1L3JC24
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1913578:LPB140 RS09115
gene id: 1913578:LPB140_RS09115
uniprot id: A0A1L3JCP8
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

1913578:LPB140 RS07425
gene id: 1913578:LPB140_RS07425
uniprot id: A0A1L3JC14
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. NspC subfamily.
messages: Catalyzes the decarboxylation of carboxynorspermidine and carboxyspermidine.
messages: Cytoplasm
messages: Homodimer.

1913578:LPB140 RS09230
gene id: 1913578:LPB140_RS09230
uniprot id: A0A1L3JCR6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioester dehydratase family. FabZ subfamily.
messages: Cytoplasm
messages: Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.

1913578:LPB140 RS09105
gene id: 1913578:LPB140_RS09105
uniprot id: A0A1L3JCX3
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

1913578:LPB140 RS02090
gene id: 1913578:LPB140_RS02090
uniprot id: A0A1L3JEB5
names: Similarity
messages: Belongs to the HesB/IscA family.

1913578:LPB140 RS07805
gene id: 1913578:LPB140_RS07805
uniprot id: A0A1L3JCB7
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. TatD-type hydrolase family.

1913578:LPB140 RS09065
gene id: 1913578:LPB140_RS09065
uniprot id: A0A1L3JCP9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidine kinase family.
messages: Cytoplasm
messages: Homotetramer.

1913578:LPB140 RS03705
gene id: 1913578:LPB140_RS03705
uniprot id: A0A1L3JAG9
names: Similarity
messages: Belongs to the TrbE/VirB4 family.

1913578:LPB140 RS12025
gene id: 1913578:LPB140_RS12025
uniprot id: A0A1L3JE97
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

1913578:LPB140 RS07130
gene id: 1913578:LPB140_RS07130
uniprot id: A0A1L3JF50
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

1913578:LPB140 RS02915
gene id: 1913578:LPB140_RS02915
uniprot id: A0A1L3J9Z2
names: Subcellular Location Annotation
messages: Membrane

1913578:LPB140 RS01400
gene id: 1913578:LPB140_RS01400
uniprot id: A0A1L3J9B4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

1913578:LPB140 RS07400
gene id: 1913578:LPB140_RS07400
uniprot id: A0A1L3JBW8
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

1913578:LPB140 RS01670
gene id: 1913578:LPB140_RS01670
uniprot id: A0A1L3J9F4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HPF/YfiA ribosome-associated protein family. Long HPF subfamily.
messages: Cytoplasm
messages: Interacts with 100S ribosomes.
messages: Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth.

1913578:LPB140 RS00680
gene id: 1913578:LPB140_RS00680
uniprot id: A0A1L3J8Y9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

1913578:LPB140 RS06375
gene id: 1913578:LPB140_RS06375
uniprot id: A0A1L3JBE8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

1913578:LPB140 RS00825
gene id: 1913578:LPB140_RS00825
uniprot id: A0A1L3J906
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1913578:LPB140 RS09265
gene id: 1913578:LPB140_RS09265
uniprot id: A0A1L3JCQ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

1913578:LPB140 RS01510
gene id: 1913578:LPB140_RS01510
uniprot id: A0A1L3J9C4
names: Similarity
messages: Belongs to the peptidase S9C family.

1913578:LPB140 RS07305
gene id: 1913578:LPB140_RS07305
uniprot id: A0A1L3JBU4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

1913578:LPB140 RS06400
gene id: 1913578:LPB140_RS06400
uniprot id: A0A1L3JBG1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COQ7 family.
messages: Binds 2 iron ions per subunit.
messages: Catalyzes the hydroxylation of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol during ubiquinone biosynthesis.
messages: Cell membrane

1913578:LPB140 RS06190
gene id: 1913578:LPB140_RS06190
uniprot id: A0A1L3JBD1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

1913578:LPB140 RS05940
gene id: 1913578:LPB140_RS05940
uniprot id: A0A1L3JB92
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

1913578:LPB140 RS06020
gene id: 1913578:LPB140_RS06020
uniprot id: A0A1L3JBE0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

1913578:LPB140 RS02350
gene id: 1913578:LPB140_RS02350
uniprot id: A0A1L3J9Q0
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1913578:LPB140 RS05550
gene id: 1913578:LPB140_RS05550
uniprot id: A0A1L3JB60
names: Function
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.
messages: Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.

1913578:LPB140 RS02540
gene id: 1913578:LPB140_RS02540
uniprot id: A0A1L3JEE5
names: Similarity
messages: Belongs to the peptidase M24B family.

1913578:LPB140 RS04525
gene id: 1913578:LPB140_RS04525
uniprot id: A0A1L3JAP0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DHBP synthase family.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Homodimer.
messages: In the C-terminal section; belongs to the GTP cyclohydrolase II family.
messages: In the N-terminal section; belongs to the DHBP synthase family.

1913578:LPB140 RS09815
gene id: 1913578:LPB140_RS09815
uniprot id: A0A1L3JCZ7
names: Cofactor
messages: Binds 1 zinc ion per subunit.

1913578:LPB140 RS09795
gene id: 1913578:LPB140_RS09795
uniprot id: A0A1L3JD82
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 3B subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

1913578:LPB140 RS06000
gene id: 1913578:LPB140_RS06000
uniprot id: A0A1L3JBC5
names: Subcellular Location Annotation
messages: Cell outer membrane

1913578:LPB140 RS10675
gene id: 1913578:LPB140_RS10675
uniprot id: A0A1L3JDH1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

1913578:LPB140 RS00510
gene id: 1913578:LPB140_RS00510
uniprot id: A0A1L3J8Y1
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MobA family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: The N-terminal domain determines nucleotide recognition and specific binding, while the C-terminal domain determines the specific binding to the target protein.
messages: Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor.

1913578:LPB140 RS11915
gene id: 1913578:LPB140_RS11915
uniprot id: A0A1L3JE11
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

1913578:LPB140 RS00875
gene id: 1913578:LPB140_RS00875
uniprot id: A0A1L3J934
names: Similarity
messages: Belongs to the carotenoid/retinoid oxidoreductase family.

1913578:LPB140 RS01385
gene id: 1913578:LPB140_RS01385
uniprot id: A0A1L3J9C5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FGAMS family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

1913578:LPB140 RS08785
gene id: 1913578:LPB140_RS08785
uniprot id: A0A1L3JCS3
names: Function
messages: Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Seems to participate in the biosynthesis of the nitrogenase metalloclusters by providing the inorganic sulfur required for the Fe-S core formation.

1913578:LPB140 RS09155
gene id: 1913578:LPB140_RS09155
uniprot id: A0A1L3JCR9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Cytoplasm
messages: Homodimer.

1913578:LPB140 RS02625
gene id: 1913578:LPB140_RS02625
uniprot id: A0A1L3J9V2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GDT1 family.
messages: Membrane

1913578:LPB140 RS07555
gene id: 1913578:LPB140_RS07555
uniprot id: A0A1L3JC33
names: Similarity
messages: Belongs to the SufE family.

1913578:LPB140 RS09445
gene id: 1913578:LPB140_RS09445
uniprot id: A0A1L3JCW2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FtsQ/DivIB family. FtsQ subfamily.
messages: Cell inner membrane
messages: Essential cell division protein.

1913578:LPB140 RS07365
gene id: 1913578:LPB140_RS07365
uniprot id: A0A1L3JBV9
names: Similarity
messages: Belongs to the virb1 family.

1913578:LPB140 RS06735
gene id: 1913578:LPB140_RS06735
uniprot id: A0A1L3JBL4
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

1913578:LPB140 RS05120
gene id: 1913578:LPB140_RS05120
uniprot id: A0A1L3JAY0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
messages: Single-chain monomer with multiple functions.

1913578:LPB140 RS08600
gene id: 1913578:LPB140_RS08600
uniprot id: A0A1L3JCI4
names: Cofactor
names: Similarity
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

1913578:LPB140 RS05780
gene id: 1913578:LPB140_RS05780
uniprot id: A0A1L3JER1
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

1913578:LPB140 RS09945
gene id: 1913578:LPB140_RS09945
uniprot id: A0A1L3JD42
names: Similarity
messages: Belongs to the PhoH family.

1913578:LPB140 RS06165
gene id: 1913578:LPB140_RS06165
uniprot id: A0A1L3JBB7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein bS6.

1913578:LPB140 RS04670
gene id: 1913578:LPB140_RS04670
uniprot id: A0A1L3JAR6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

1913578:LPB140 RS01360
gene id: 1913578:LPB140_RS01360
uniprot id: A0A1L3J995
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

1913578:LPB140 RS09860
gene id: 1913578:LPB140_RS09860
uniprot id: A0A1L3JD29
names: Similarity
messages: Belongs to the GSP E family.

1913578:LPB140 RS09310
gene id: 1913578:LPB140_RS09310
uniprot id: A0A1L3JCT0
names: Subcellular Location Annotation
messages: Membrane

1913578:LPB140 RS08305
gene id: 1913578:LPB140_RS08305
uniprot id: A0A1L3JCC5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.

1913578:LPB140 RS01045
gene id: 1913578:LPB140_RS01045
uniprot id: A0A1L3J940
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1913578:LPB140 RS09380
gene id: 1913578:LPB140_RS09380
uniprot id: A0A1L3JF30
names: Function
names: Similarity
names: Subunit
messages: APS kinase catalyzes the synthesis of activated sulfate.
messages: Belongs to the APS kinase family.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.
messages: Catalyzes the synthesis of activated sulfate.
messages: Heterodimer composed of CysD, the smaller subunit, and CysN.
messages: In the C-terminal section; belongs to the APS kinase family.
messages: In the N-terminal section; belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.
messages: Proposed to provide activated sulfate for transfer to Nod factor. ATP sulfurylase may be the GTPase, regulating ATP sulfurylase activity.
messages: Sulfate-activating enzymes, NodP and NodQ, may be physically associated.
messages: With CysD forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway. APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD.

1913578:LPB140 RS05080
gene id: 1913578:LPB140_RS05080
uniprot id: A0A1L3JAW1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.

1913578:LPB140 RS04575
gene id: 1913578:LPB140_RS04575
uniprot id: A0A1L3JEK7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1913578:LPB140 RS09450
gene id: 1913578:LPB140_RS09450
uniprot id: A0A1L3JD08
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

1913578:LPB140 RS06005
gene id: 1913578:LPB140_RS06005
uniprot id: A0A1L3JB98
names: Subcellular Location Annotation
messages: Membrane

1913578:LPB140 RS01255
gene id: 1913578:LPB140_RS01255
uniprot id: A0A1L3JEA1
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.

1913578:LPB140 RS04870
gene id: 1913578:LPB140_RS04870
uniprot id: A0A1L3JAU8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

1913578:LPB140 RS09410
gene id: 1913578:LPB140_RS09410
uniprot id: A0A1L3JD21
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

1913578:LPB140 RS04970
gene id: 1913578:LPB140_RS04970
uniprot id: A0A1L3JAV4
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

1913578:LPB140 RS02840
gene id: 1913578:LPB140_RS02840
uniprot id: A0A1L3J9X9
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

1913578:LPB140 RS10595
gene id: 1913578:LPB140_RS10595
uniprot id: A0A1L3JFB2
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

1913578:LPB140 RS10935
gene id: 1913578:LPB140_RS10935
uniprot id: A0A1L3JDJ0
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

1913578:LPB140 RS08885
gene id: 1913578:LPB140_RS08885
uniprot id: A0A1L3JCK0
names: Similarity
messages: Belongs to the hcp beta-lactamase family.

1913578:LPB140 RS09040
gene id: 1913578:LPB140_RS09040
uniprot id: A0A1L3JCN6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamD family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

1913578:LPB140 RS04880
gene id: 1913578:LPB140_RS04880
uniprot id: A0A1L3JAU3
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

1913578:LPB140 RS00995
gene id: 1913578:LPB140_RS00995
uniprot id: A0A1L3J954
names: Function
names: Similarity
messages: Belongs to the polysaccharide deacetylase family.
messages: Is involved in generating a small heat-stable compound (Nod), an acylated oligomer of N-acetylglucosamine, that stimulates mitosis in various plant protoplasts.

1913578:LPB140 RS07595
gene id: 1913578:LPB140_RS07595
uniprot id: A0A1L3JBZ6
names: Similarity
messages: Belongs to the PspA/IM30 family.

1913578:LPB140 RS01600
gene id: 1913578:LPB140_RS01600
uniprot id: A0A1L3J9D4
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

1913578:LPB140 RS02675
gene id: 1913578:LPB140_RS02675
uniprot id: A0A1L3J9U6
names: Similarity
messages: Belongs to the iron/ascorbate-dependent oxidoreductase family.

1913578:LPB140 RS00640
gene id: 1913578:LPB140_RS00640
uniprot id: A0A1L3J8Y0
names: Similarity
messages: Belongs to the SCO1/2 family.

1913578:LPB140 RS10435
gene id: 1913578:LPB140_RS10435
uniprot id: A0A1L3JDJ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family.
messages: Membrane

1913578:LPB140 RS11870
gene id: 1913578:LPB140_RS11870
uniprot id: A0A1L3JDY4
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvB family.
messages: Cytoplasm
messages: Has 3 domains, the large (RuvB-L) and small ATPase (RuvB-S) domains and the C-terminal head (RuvB-H) domain. The head domain binds DNA, while the ATPase domains jointly bind ATP, ADP or are empty depending on the state of the subunit in the translocation cycle. During a single DNA translocation step the structure of each domain remains the same, but their relative positions change.
messages: Homohexamer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time. Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange. Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration. The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration. Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.

1913578:LPB140 RS03785
gene id: 1913578:LPB140_RS03785
uniprot id: A0A1L3JAC2
names: Similarity
messages: Belongs to the GMC oxidoreductase family.

1913578:LPB140 RS09245
gene id: 1913578:LPB140_RS09245
uniprot id: A0A1L3JCZ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

1913578:LPB140 RS01730
gene id: 1913578:LPB140_RS01730
uniprot id: A0A1L3J9F5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

1913578:LPB140 RS03495
gene id: 1913578:LPB140_RS03495
uniprot id: A0A1L3JA69
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1913578:LPB140 RS05345
gene id: 1913578:LPB140_RS05345
uniprot id: A0A1L3JEP7
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

1913578:LPB140 RS03500
gene id: 1913578:LPB140_RS03500
uniprot id: A0A1L3JA78
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1913578:LPB140 RS08410
gene id: 1913578:LPB140_RS08410
uniprot id: A0A1L3JCH7
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

1913578:LPB140 RS00410
gene id: 1913578:LPB140_RS00410
uniprot id: A0A1L3JE58
names: Similarity
messages: Belongs to the HpcH/HpaI aldolase family.

1913578:LPB140 RS04130
gene id: 1913578:LPB140_RS04130
uniprot id: A0A1L3JAG8
names: Subcellular Location Annotation
messages: Membrane

1913578:LPB140 RS09035
gene id: 1913578:LPB140_RS09035
uniprot id: A0A1L3JCQ2
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

1913578:LPB140 RS05040
gene id: 1913578:LPB140_RS05040
uniprot id: A0A1L3JAX5
names: Similarity
messages: Belongs to the DEAD box helicase family.

1913578:LPB140 RS06060
gene id: 1913578:LPB140_RS06060
uniprot id: A0A1L3JBB1
names: Similarity
messages: Belongs to the ferredoxin--NADP reductase type 1 family.

1913578:LPB140 RS11410
gene id: 1913578:LPB140_RS11410
uniprot id: A0A1L3JDV2
names: Subcellular Location Annotation
messages: Membrane

1913578:LPB140 RS11790
gene id: 1913578:LPB140_RS11790
uniprot id: A0A1L3JDY5
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fluoride channel Fluc/FEX (TC 1.A.43) family.
messages: Cell membrane
messages: Fluoride-specific ion channel. Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane
messages: Na(+) is not transported, but it plays an essential structural role and its presence is essential for fluoride channel function.

1913578:LPB140 RS07115
gene id: 1913578:LPB140_RS07115
uniprot id: A0A1L3JBS7
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1913578:LPB140 RS00480
gene id: 1913578:LPB140_RS00480
uniprot id: A0A1L3J8V6
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. NasA/NapA/NarB subfamily.

1913578:LPB140 RS04025
gene id: 1913578:LPB140_RS04025
uniprot id: A0A1L3JAE7
names: Subcellular Location Annotation
messages: Membrane

1913578:LPB140 RS02710
gene id: 1913578:LPB140_RS02710
uniprot id: A0A1L3JEF9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

1913578:LPB140 RS10940
gene id: 1913578:LPB140_RS10940
uniprot id: A0A1L3JDJ7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

1913578:LPB140 RS04075
gene id: 1913578:LPB140_RS04075
uniprot id: A0A1L3JEI6
names: Similarity
messages: Belongs to the band 7/mec-2 family. HflK subfamily.

1913578:LPB140 RS06995
gene id: 1913578:LPB140_RS06995
uniprot id: A0A1L3JBQ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1913578:LPB140 RS11720
gene id: 1913578:LPB140_RS11720
uniprot id: A0A1L3JE47
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

1913578:LPB140 RS09830
gene id: 1913578:LPB140_RS09830
uniprot id: A0A1L3JD34
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

1913578:LPB140 RS04160
gene id: 1913578:LPB140_RS04160
uniprot id: A0A1L3JAI4
names: Similarity
messages: Belongs to the GST superfamily.

1913578:LPB140 RS07820
gene id: 1913578:LPB140_RS07820
uniprot id: A0A1L3JC52
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Hfq family.
messages: Homohexamer.
messages: RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs.

1913578:LPB140 RS09465
gene id: 1913578:LPB140_RS09465
uniprot id: A0A1L3JCV2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

1913578:LPB140 RS04070
gene id: 1913578:LPB140_RS04070
uniprot id: A0A1L3JAG3
names: Function
names: Similarity
messages: Belongs to the band 7/mec-2 family. HflC subfamily.
messages: HflC and HflK could regulate a protease.

1913578:LPB140 RS08665
gene id: 1913578:LPB140_RS08665
uniprot id: A0A1L3JCQ4
names: Similarity
messages: Belongs to the polyphosphate kinase 2 (PPK2) family. Class I subfamily.

1913578:LPB140 RS09900
gene id: 1913578:LPB140_RS09900
uniprot id: A0A1L3JD24
names: Similarity
messages: Belongs to the ClpX chaperone family. HslU subfamily.

1913578:LPB140 RS02045
gene id: 1913578:LPB140_RS02045
uniprot id: A0A1L3J9M5
names: Similarity
messages: In the C-terminal section; belongs to the transpeptidase family.
messages: In the N-terminal section; belongs to the glycosyltransferase 51 family.

1913578:LPB140 RS04305
gene id: 1913578:LPB140_RS04305
uniprot id: A0A1L3JAR4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsX family.
messages: Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
messages: Cytoplasm
messages: Homodimer. Probably interacts with PlsY.

1913578:LPB140 RS01920
gene id: 1913578:LPB140_RS01920
uniprot id: A0A1L3J9H3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell membrane
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

1913578:LPB140 RS05775
gene id: 1913578:LPB140_RS05775
uniprot id: A0A1L3JES7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FPG family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
messages: Monomer.

1913578:LPB140 RS05520
gene id: 1913578:LPB140_RS05520
uniprot id: A0A1L3JB38
names: Function
names: Subunit
messages: E1 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the decarboxylation of 2-oxoglutarate, the first step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).
messages: Homodimer. Part of the 2-oxoglutarate dehydrogenase (OGDH) complex composed of E1 (2-oxoglutarate dehydrogenase), E2 (dihydrolipoamide succinyltransferase) and E3 (dihydrolipoamide dehydrogenase); the complex contains multiple copies of the three enzymatic components (E1, E2 and E3).

1913578:LPB140 RS11290
gene id: 1913578:LPB140_RS11290
uniprot id: A0A1L3JDQ7
names: Similarity
messages: Belongs to the UbiH/COQ6 family.

1913578:LPB140 RS04345
gene id: 1913578:LPB140_RS04345
uniprot id: A0A1L3JAL6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Membrane

1913578:LPB140 RS06715
gene id: 1913578:LPB140_RS06715
uniprot id: A0A1L3JBJ4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

1913578:LPB140 RS05740
gene id: 1913578:LPB140_RS05740
uniprot id: A0A1L3JB81
names: Caution
names: Function
names: Similarity
messages: Belongs to the dUTPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

1913578:LPB140 RS10220
gene id: 1913578:LPB140_RS10220
uniprot id: A0A1L3JDC4
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

1913578:LPB140 RS09575
gene id: 1913578:LPB140_RS09575
uniprot id: A0A1L3JCY5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

1913578:LPB140 RS08965
gene id: 1913578:LPB140_RS08965
uniprot id: A0A1L3JCN8
names: Function
names: Similarity
messages: Belongs to the glutaredoxin family.
messages: Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins.

1913578:LPB140 RS00900
gene id: 1913578:LPB140_RS00900
uniprot id: A0A1L3J962
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0314 family.
messages: Cell membrane

1913578:LPB140 RS02980
gene id: 1913578:LPB140_RS02980
uniprot id: A0A1L3JA17
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 1 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

1913578:LPB140 RS09425
gene id: 1913578:LPB140_RS09425
uniprot id: A0A1L3JCV8
names: Similarity
messages: Belongs to the dGTPase family. Type 2 subfamily.

1913578:LPB140 RS03140
gene id: 1913578:LPB140_RS03140
uniprot id: A0A1L3JA37
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Cell inner membrane
messages: Component of the type II secretion system inner membrane complex required for the energy-dependent secretion of extracellular factors such as proteases and toxins from the periplasm.
messages: Membrane

1913578:LPB140 RS02785
gene id: 1913578:LPB140_RS02785
uniprot id: A0A1L3J9W3
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS1 family.
messages: Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence.

1913578:LPB140 RS00095
gene id: 1913578:LPB140_RS00095
uniprot id: A0A1L3JE35
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AB hydrolase superfamily. MetX family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.

1913578:LPB140 RS08295
gene id: 1913578:LPB140_RS08295
uniprot id: A0A1L3JCG1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Cell inner membrane
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. SRP is a ribonucleoprotein composed of Ffh and a 4.5S RNA molecule.

1913578:LPB140 RS09735
gene id: 1913578:LPB140_RS09735
uniprot id: A0A1L3JD72
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1913578:LPB140 RS00615
gene id: 1913578:LPB140_RS00615
uniprot id: A0A1L3J8X9
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

1913578:LPB140 RS05190
gene id: 1913578:LPB140_RS05190
uniprot id: A0A1L3JB03
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

1913578:LPB140 RS05055
gene id: 1913578:LPB140_RS05055
uniprot id: A0A1L3JEP4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the carboxylate-amine ligase family. Glutamate--cysteine ligase type 2 subfamily.
messages: Belongs to the glutamate--cysteine ligase type 2 family. EgtA subfamily.
messages: Catalyzes the synthesis of gamma-glutamylcysteine (gamma-GC).
messages: Homodimer or monomer when oxidized or reduced, respectively.
messages: chloroplast

1913578:LPB140 RS06595
gene id: 1913578:LPB140_RS06595
uniprot id: A0A1L3JBR8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Cell membrane
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

1913578:LPB140 RS08275
gene id: 1913578:LPB140_RS08275
uniprot id: A0A1L3JCB3
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

1913578:LPB140 RS11105
gene id: 1913578:LPB140_RS11105
uniprot id: A0A1L3JDK9
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1913578:LPB140 RS09025
gene id: 1913578:LPB140_RS09025
uniprot id: A0A1L3JCP0
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1913578:LPB140 RS11660
gene id: 1913578:LPB140_RS11660
uniprot id: A0A1L3JDV1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

1913578:LPB140 RS02120
gene id: 1913578:LPB140_RS02120
uniprot id: A0A1L3J9M9
names: Similarity
messages: Belongs to the BolA/IbaG family.

1913578:LPB140 RS04210
gene id: 1913578:LPB140_RS04210
uniprot id: A0A1L3JAI3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

1913578:LPB140 RS05065
gene id: 1913578:LPB140_RS05065
uniprot id: A0A1L3JAW7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

1913578:LPB140 RS01580
gene id: 1913578:LPB140_RS01580
uniprot id: A0A1L3J9C3
names: Similarity
messages: In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.
messages: In the N-terminal section; belongs to the malic enzymes family.

1913578:LPB140 RS04050
gene id: 1913578:LPB140_RS04050
uniprot id: A0A1L3JAF5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

1913578:LPB140 RS05745
gene id: 1913578:LPB140_RS05745
uniprot id: A0A1L3JEQ8
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1913578:LPB140 RS00325
gene id: 1913578:LPB140_RS00325
uniprot id: A0A1L3J8U7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

1913578:LPB140 RS08810
gene id: 1913578:LPB140_RS08810
uniprot id: A0A1L3JCL2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1913578:LPB140 RS09020
gene id: 1913578:LPB140_RS09020
uniprot id: A0A1L3JCM0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
messages: Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).
messages: Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1913578:LPB140 RS11630
gene id: 1913578:LPB140_RS11630
uniprot id: A0A1L3JDV4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

1913578:LPB140 RS07750
gene id: 1913578:LPB140_RS07750
uniprot id: A0A1L3JC31
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1913578:LPB140 RS00100
gene id: 1913578:LPB140_RS00100
uniprot id: A0A1L3J8R2
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

1913578:LPB140 RS06470
gene id: 1913578:LPB140_RS06470
uniprot id: A0A1L3JBH5
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

1913578:LPB140 RS00295
gene id: 1913578:LPB140_RS00295
uniprot id: A0A1L3J8V4
names: Subcellular Location Annotation
messages: Membrane

1913578:LPB140 RS00440
gene id: 1913578:LPB140_RS00440
uniprot id: A0A1L3J8Y5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1913578:LPB140 RS07615
gene id: 1913578:LPB140_RS07615
uniprot id: A0A1L3JC17
names: Subcellular Location Annotation
messages: Membrane

1913578:LPB140 RS06760
gene id: 1913578:LPB140_RS06760
uniprot id: A0A1L3JBK8
names: Function
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

1913578:LPB140 RS02320
gene id: 1913578:LPB140_RS02320
uniprot id: A0A1L3J9N1
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
messages: In the C-terminal section; belongs to the NAD synthetase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1913578:LPB140 RS07510
gene id: 1913578:LPB140_RS07510
uniprot id: A0A1L3JC03
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. Biotin synthase family.
messages: Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
messages: Homodimer.

1913578:LPB140 RS06250
gene id: 1913578:LPB140_RS06250
uniprot id: A0A1L3JBH2
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family.

1913578:LPB140 RS07135
gene id: 1913578:LPB140_RS07135
uniprot id: A0A1L3JBS2
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

1913578:LPB140 RS05655
gene id: 1913578:LPB140_RS05655
uniprot id: A0A1L3JB56
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

1913578:LPB140 RS08745
gene id: 1913578:LPB140_RS08745
uniprot id: A0A1L3JCH9
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PdxA family.
messages: Binds 1 divalent metal cation per subunit. Can use ions such as Zn(2+), Mg(2+) or Co(2+).
messages: Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L-threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP).
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The active site is located at the dimer interface.

1913578:LPB140 RS05540
gene id: 1913578:LPB140_RS05540
uniprot id: A0A1L3JB27
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Catalyzes the dehydration of 6-phospho-D-gluconate to 2-dehydro-3-deoxy-6-phospho-D-gluconate.

1913578:LPB140 RS04260
gene id: 1913578:LPB140_RS04260
uniprot id: A0A1L3JAI8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the O-antigen polymerase family.
messages: Membrane

1913578:LPB140 RS00830
gene id: 1913578:LPB140_RS00830
uniprot id: A0A1L3J947
names: Function
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.
messages: Catalyzes the reversible phosphorylation of pyruvate and phosphate.

1913578:LPB140 RS05685
gene id: 1913578:LPB140_RS05685
uniprot id: A0A1L3JB52
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1913578:LPB140 RS05050
gene id: 1913578:LPB140_RS05050
uniprot id: A0A1L3JAV7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1913578:LPB140 RS08635
gene id: 1913578:LPB140_RS08635
uniprot id: A0A1L3JCL8
names: Similarity
messages: Belongs to the peptidase M13 family.

1913578:LPB140 RS03025
gene id: 1913578:LPB140_RS03025
uniprot id: A0A1L3J9Z9
names: Function
names: Similarity
messages: Belongs to the sigma-54 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

1913578:LPB140 RS02415
gene id: 1913578:LPB140_RS02415
uniprot id: A0A1L3JEE0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

1913578:LPB140 RS06310
gene id: 1913578:LPB140_RS06310
uniprot id: A0A1L3JBI1
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

1913578:LPB140 RS03520
gene id: 1913578:LPB140_RS03520
uniprot id: A0A1L3JA81
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1913578:LPB140 RS06515
gene id: 1913578:LPB140_RS06515
uniprot id: A0A1L3JBI2
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

1913578:LPB140 RS12075
gene id: 1913578:LPB140_RS12075
uniprot id: A0A1L3JE43
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EamA transporter family.
messages: Membrane

1913578:LPB140 RS10925
gene id: 1913578:LPB140_RS10925
uniprot id: A0A1L3JDK0
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the gamma-glutamyltransferase family.
messages: Cleaved by autocatalysis into a large and a small subunit.
messages: This enzyme consists of two polypeptide chains, which are synthesized in precursor form from a single polypeptide.

1913578:LPB140 RS10300
gene id: 1913578:LPB140_RS10300
uniprot id: A0A1L3JDA1
names: Similarity
messages: Belongs to the HIBADH-related family.

1913578:LPB140 RS02310
gene id: 1913578:LPB140_RS02310
uniprot id: A0A1L3J9Q5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

1913578:LPB140 RS07585
gene id: 1913578:LPB140_RS07585
uniprot id: A0A1L3JC00
names: Subcellular Location Annotation
messages: Membrane

1913578:LPB140 RS09180
gene id: 1913578:LPB140_RS09180
uniprot id: A0A1L3JCQ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmF/CycK/Ccl1/NrfE/CcsA family.
messages: Cell inner membrane
messages: Membrane

1913578:LPB140 RS09785
gene id: 1913578:LPB140_RS09785
uniprot id: A0A1L3JD25
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 1 subfamily.
messages: Cell membrane
messages: Heterotetramer composed of ParC and ParE.
messages: Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.

1913578:LPB140 RS00550
gene id: 1913578:LPB140_RS00550
uniprot id: A0A1L3JEE9
names: Similarity
messages: Belongs to the ArsC family.

1913578:LPB140 RS02965
gene id: 1913578:LPB140_RS02965
uniprot id: A0A1L3JA05
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

1913578:LPB140 RS00820
gene id: 1913578:LPB140_RS00820
uniprot id: A0A1L3JE86
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1913578:LPB140 RS08160
gene id: 1913578:LPB140_RS08160
uniprot id: A0A1L3JF12
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1913578:LPB140 RS01695
gene id: 1913578:LPB140_RS01695
uniprot id: A0A1L3J9F1
names: Function
names: Similarity
messages: Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PDRP subfamily.
messages: Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation/dephosphorylation.

1913578:LPB140 RS08765
gene id: 1913578:LPB140_RS08765
uniprot id: A0A1L3JCJ8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinylarginine dihydrolase family.
messages: Catalyzes the hydrolysis of N(2)-succinylarginine into N(2)-succinylornithine, ammonia and CO(2).
messages: Homodimer.

1913578:LPB140 RS11325
gene id: 1913578:LPB140_RS11325
uniprot id: A0A1L3JDS8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Reduced FMN (FMNH(2)).

1913578:LPB140 RS02665
gene id: 1913578:LPB140_RS02665
uniprot id: A0A1L3J9V5
names: Similarity
messages: Belongs to the GST superfamily.

1913578:LPB140 RS04625
gene id: 1913578:LPB140_RS04625
uniprot id: A0A1L3JAX2
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

1913578:LPB140 RS09890
gene id: 1913578:LPB140_RS09890
uniprot id: A0A1L3JD73
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

1913578:LPB140 RS03160
gene id: 1913578:LPB140_RS03160
uniprot id: A0A1L3JA29
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP J family.
messages: Cell inner membrane
messages: Membrane

1913578:LPB140 RS11685
gene id: 1913578:LPB140_RS11685
uniprot id: A0A1L3JDY9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

1913578:LPB140 RS04500
gene id: 1913578:LPB140_RS04500
uniprot id: A0A1L3JAM4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRA-PH family.
messages: Cytoplasm

1913578:LPB140 RS04545
gene id: 1913578:LPB140_RS04545
uniprot id: A0A1L3JAN9
names: Function
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.
messages: Catalyzes the isomerization of citrate to isocitrate via cis-aconitate.

1913578:LPB140 RS05610
gene id: 1913578:LPB140_RS05610
uniprot id: A0A1L3JBB0
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dCTP deaminase family.
messages: Catalyzes the deamination of dCTP to dUTP.
messages: Homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1913578:LPB140 RS06885
gene id: 1913578:LPB140_RS06885
uniprot id: A0A1L3JBM4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the trans-sulfuration enzymes family. MetZ subfamily.
messages: Catalyzes the formation of L-homocysteine from O-succinyl-L-homoserine (OSHS) and hydrogen sulfide.
messages: Homotetramer.

1913578:LPB140 RS08825
gene id: 1913578:LPB140_RS08825
uniprot id: A0A1L3JCQ0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.
messages: Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA.
messages: Cytoplasm
messages: Homodimer.

1913578:LPB140 RS06865
gene id: 1913578:LPB140_RS06865
uniprot id: A0A1L3JBP0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0). The b'-subunit is a diverged and duplicated form of b found in plants and photosynthetic bacteria.
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

1913578:LPB140 RS08260
gene id: 1913578:LPB140_RS08260
uniprot id: A0A1L3JCB8
names: Similarity
messages: Belongs to the GST superfamily. NadH family.

1913578:LPB140 RS02780
gene id: 1913578:LPB140_RS02780
uniprot id: A0A1L3J9X5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

1913578:LPB140 RS05175
gene id: 1913578:LPB140_RS05175
uniprot id: A0A1L3JB59
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

1913578:LPB140 RS06875
gene id: 1913578:LPB140_RS06875
uniprot id: A0A1L3JBM8
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

1913578:LPB140 RS08780
gene id: 1913578:LPB140_RS08780
uniprot id: A0A1L3JF13
names: Similarity
messages: Belongs to the adrenodoxin/putidaredoxin family.

1913578:LPB140 RS08905
gene id: 1913578:LPB140_RS08905
uniprot id: A0A1L3JCN2
names: Similarity
messages: Belongs to the bacterial sugar transferase family.

1913578:LPB140 RS11080
gene id: 1913578:LPB140_RS11080
uniprot id: A0A1L3JDK5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1913578:LPB140 RS05560
gene id: 1913578:LPB140_RS05560
uniprot id: A0A1L3JB32
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DksA family.
messages: Cytoplasm
messages: Interacts directly with the RNA polymerase.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters.

1913578:LPB140 RS08065
gene id: 1913578:LPB140_RS08065
uniprot id: A0A1L3JCF6
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1913578:LPB140 RS04410
gene id: 1913578:LPB140_RS04410
uniprot id: A0A1L3JAK4
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

1913578:LPB140 RS05410
gene id: 1913578:LPB140_RS05410
uniprot id: A0A1L3JB35
names: Similarity
messages: Belongs to the glycosyl hydrolase 5 (cellulase A) family.

1913578:LPB140 RS09915
gene id: 1913578:LPB140_RS09915
uniprot id: A0A1L3JD39
names: Similarity
messages: Belongs to the nitroreductase family. HadB/RutE subfamily.

1913578:LPB140 RS09595
gene id: 1913578:LPB140_RS09595
uniprot id: A0A1L3JCX1
names: Similarity
messages: Belongs to the pseudomonas-type ThrB family.

1913578:LPB140 RS10955
gene id: 1913578:LPB140_RS10955
uniprot id: A0A1L3JDI5
names: Similarity
names: Subunit
messages: Belongs to the P(II) protein family.
messages: Homotrimer.

1913578:LPB140 RS08230
gene id: 1913578:LPB140_RS08230
uniprot id: A0A1L3JCE8
names: Function
names: Similarity
messages: Belongs to the peroxiredoxin family. Prx5 subfamily.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

1913578:LPB140 RS03720
gene id: 1913578:LPB140_RS03720
uniprot id: A0A1L3JAA7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TrbI/VirB10 family.
messages: Membrane

1913578:LPB140 RS08070
gene id: 1913578:LPB140_RS08070
uniprot id: A0A1L3JC88
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

1913578:LPB140 RS11890
gene id: 1913578:LPB140_RS11890
uniprot id: A0A1L3JDY7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

1913578:LPB140 RS03385
gene id: 1913578:LPB140_RS03385
uniprot id: A0A1L3JA61
names: Subcellular Location Annotation
messages: Membrane

1913578:LPB140 RS01520
gene id: 1913578:LPB140_RS01520
uniprot id: A0A1L3J9C9
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1913578:LPB140 RS02360
gene id: 1913578:LPB140_RS02360
uniprot id: A0A1L3JEB1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
messages: Cytoplasm
messages: Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.

1913578:LPB140 RS09710
gene id: 1913578:LPB140_RS09710
uniprot id: A0A1L3JFD3
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

1913578:LPB140 RS07215
gene id: 1913578:LPB140_RS07215
uniprot id: A0A1L3JBU9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 2 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1913578:LPB140 RS10660
gene id: 1913578:LPB140_RS10660
uniprot id: A0A1L3JDN6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA gyrase inhibitor YacG family.
messages: Binds 1 zinc ion.
messages: Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase.
messages: Interacts with GyrB.

1913578:LPB140 RS05305
gene id: 1913578:LPB140_RS05305
uniprot id: A0A1L3JAZ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell membrane

1913578:LPB140 RS09660
gene id: 1913578:LPB140_RS09660
uniprot id: A0A1L3JCZ8
names: Similarity
messages: Belongs to the extradiol ring-cleavage dioxygenase family.

1913578:LPB140 RS05285
gene id: 1913578:LPB140_RS05285
uniprot id: A0A1L3JB09
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

1913578:LPB140 RS00895
gene id: 1913578:LPB140_RS00895
uniprot id: A0A1L3J920
names: Similarity
messages: Belongs to the MipA/OmpV family.

1913578:LPB140 RS07320
gene id: 1913578:LPB140_RS07320
uniprot id: A0A1L3JBW5
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

1913578:LPB140 RS01785
gene id: 1913578:LPB140_RS01785
uniprot id: A0A1L3JEB6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

1913578:LPB140 RS01680
gene id: 1913578:LPB140_RS01680
uniprot id: A0A1L3J9D2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

1913578:LPB140 RS09080
gene id: 1913578:LPB140_RS09080
uniprot id: A0A1L3JCU4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

1913578:LPB140 RS04750
gene id: 1913578:LPB140_RS04750
uniprot id: A0A1L3JEL3
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LipB family.
messages: Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
messages: Cytoplasm
messages: In the reaction, the free carboxyl group of octanoic acid is attached via an amide linkage to the epsilon-amino group of a specific lysine residue of lipoyl domains of lipoate-dependent enzymes.

1913578:LPB140 RS03580
gene id: 1913578:LPB140_RS03580
uniprot id: A0A1L3JAE5
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family. GalD subfamily.

1913578:LPB140 RS06965
gene id: 1913578:LPB140_RS06965
uniprot id: A0A1L3JBR2
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Member of the two-component regulatory system NreB/NreC involved in the control of dissimilatory nitrate/nitrite reduction in response to oxygen. NreB functions as a direct oxygen sensor histidine kinase which is autophosphorylated, in the absence of oxygen, probably at the conserved histidine residue, and transfers its phosphate group probably to a conserved aspartate residue of NreC. NreB/NreC activates the expression of the nitrate (narGHJI) and nitrite (nir) reductase operons, as well as the putative nitrate transporter gene narT.

1913578:LPB140 RS08710
gene id: 1913578:LPB140_RS08710
uniprot id: A0A1L3JCK8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

1913578:LPB140 RS04930
gene id: 1913578:LPB140_RS04930
uniprot id: A0A1L3JAV6
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1913578:LPB140 RS09460
gene id: 1913578:LPB140_RS09460
uniprot id: A0A1L3JF28
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

1913578:LPB140 RS07880
gene id: 1913578:LPB140_RS07880
uniprot id: A0A1L3JC40
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.

1913578:LPB140 RS07885
gene id: 1913578:LPB140_RS07885
uniprot id: A0A1L3JC67
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Catalyzes the sodium-dependent uptake of extracellular L-proline.
messages: Cell inner membrane
messages: Membrane

1913578:LPB140 RS11935
gene id: 1913578:LPB140_RS11935
uniprot id: A0A1L3JDZ7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

1913578:LPB140 RS11860
gene id: 1913578:LPB140_RS11860
uniprot id: A0A1L3JDZ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

1913578:LPB140 RS07905
gene id: 1913578:LPB140_RS07905
uniprot id: A0A1L3JEY1
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.
messages: Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).
messages: The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.
messages: The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1.

1913578:LPB140 RS08130
gene id: 1913578:LPB140_RS08130
uniprot id: A0A1L3JC93
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

1913578:LPB140 RS03165
gene id: 1913578:LPB140_RS03165
uniprot id: A0A1L3JA22
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP K family.
messages: Cell inner membrane
messages: Membrane

1913578:LPB140 RS06845
gene id: 1913578:LPB140_RS06845
uniprot id: A0A1L3JBN6
names: Function
names: Similarity
messages: A possible function for this protein is to guide the assembly of the membrane sector of the ATPase enzyme complex.
messages: Belongs to the bacterial AtpI family.

1913578:LPB140 RS05980
gene id: 1913578:LPB140_RS05980
uniprot id: A0A1L3JBA0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm

1913578:LPB140 RS07485
gene id: 1913578:LPB140_RS07485
uniprot id: A0A1L3JEZ3
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

1913578:LPB140 RS00355
gene id: 1913578:LPB140_RS00355
uniprot id: A0A1L3J8T9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsuA/YedE (TC 9.B.102) family.
messages: Cell inner membrane
messages: Membrane

1913578:LPB140 RS02970
gene id: 1913578:LPB140_RS02970
uniprot id: A0A1L3JEF1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0126 family.
messages: Membrane

1913578:LPB140 RS06460
gene id: 1913578:LPB140_RS06460
uniprot id: A0A1L3JBH3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the O-antigen polymerase family.
messages: Membrane

1913578:LPB140 RS10080
gene id: 1913578:LPB140_RS10080
uniprot id: A0A1L3JD30
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
messages: Cell inner membrane
messages: Membrane

1913578:LPB140 RS02205
gene id: 1913578:LPB140_RS02205
uniprot id: A0A1L3JED2
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1913578:LPB140 RS04705
gene id: 1913578:LPB140_RS04705
uniprot id: A0A1L3JAQ3
names: Similarity
messages: Belongs to the ClpA/ClpB family.

1913578:LPB140 RS07735
gene id: 1913578:LPB140_RS07735
uniprot id: A0A1L3JC46
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1913578:LPB140 RS05505
gene id: 1913578:LPB140_RS05505
uniprot id: A0A1L3JB37
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF2.
messages: Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.

1913578:LPB140 RS01950
gene id: 1913578:LPB140_RS01950
uniprot id: A0A1L3J9J9
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

1913578:LPB140 RS04415
gene id: 1913578:LPB140_RS04415
uniprot id: A0A1L3JAM1
names: Function
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

1913578:LPB140 RS07225
gene id: 1913578:LPB140_RS07225
uniprot id: A0A1L3JBV0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1913578:LPB140 RS07790
gene id: 1913578:LPB140_RS07790
uniprot id: A0A1L3JC47
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

1913578:LPB140 RS09045
gene id: 1913578:LPB140_RS09045
uniprot id: A0A1L3JCR5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

1913578:LPB140 RS07360
gene id: 1913578:LPB140_RS07360
uniprot id: A0A1L3JEX2
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

1913578:LPB140 RS11715
gene id: 1913578:LPB140_RS11715
uniprot id: A0A1L3JDX7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

1913578:LPB140 RS11110
gene id: 1913578:LPB140_RS11110
uniprot id: A0A1L3JDN4
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

1913578:LPB140 RS02790
gene id: 1913578:LPB140_RS02790
uniprot id: A0A1L3J9W2
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

1913578:LPB140 RS02505
gene id: 1913578:LPB140_RS02505
uniprot id: A0A1L3J9U2
names: Similarity
messages: Belongs to the sodium:galactoside symporter (TC 2.A.2) family.

1913578:LPB140 RS11675
gene id: 1913578:LPB140_RS11675
uniprot id: A0A1L3JDW3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

1913578:LPB140 RS01315
gene id: 1913578:LPB140_RS01315
uniprot id: A0A1L3J998
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueG family.
messages: Binds 2 [4Fe-4S] clusters per monomer.
messages: Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1913578:LPB140 RS11735
gene id: 1913578:LPB140_RS11735
uniprot id: A0A1L3JDZ6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

1913578:LPB140 RS06695
gene id: 1913578:LPB140_RS06695
uniprot id: A0A1L3JBJ7
names: Similarity
messages: Belongs to the CFA/CMAS family.

1913578:LPB140 RS09840
gene id: 1913578:LPB140_RS09840
uniprot id: A0A1L3JD10
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase epsilon chain family.
messages: Membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

1913578:LPB140 RS04770
gene id: 1913578:LPB140_RS04770
uniprot id: A0A1L3JER5
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Rieske iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.
messages: Membrane
messages: The Rieske protein is a high potential 2Fe-2S protein.
messages: The main subunits of complex b-c1 are: cytochrome b, cytochrome c1 and the Rieske protein.

1913578:LPB140 RS05145
gene id: 1913578:LPB140_RS05145
uniprot id: A0A1L3JAX4
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

1913578:LPB140 RS07480
gene id: 1913578:LPB140_RS07480
uniprot id: A0A1L3JBZ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm

1913578:LPB140 RS11705
gene id: 1913578:LPB140_RS11705
uniprot id: A0A1L3JDY2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

1913578:LPB140 RS01825
gene id: 1913578:LPB140_RS01825
uniprot id: A0A1L3J9H2
names: Cofactor
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.
messages: Probably binds two magnesium or manganese ions per subunit.

1913578:LPB140 RS00450
gene id: 1913578:LPB140_RS00450
uniprot id: A0A1L3J8W5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arsenical resistance-3 (ACR3) (TC 2.A.59) family.
messages: Cell membrane
messages: Membrane

1913578:LPB140 RS11335
gene id: 1913578:LPB140_RS11335
uniprot id: A0A1L3JDP6
names: Subcellular Location Annotation
messages: Membrane

1913578:LPB140 RS10770
gene id: 1913578:LPB140_RS10770
uniprot id: A0A1L3JDH6
names: Subcellular Location Annotation
messages: Membrane

1913578:LPB140 RS07460
gene id: 1913578:LPB140_RS07460
uniprot id: A0A1L3JBX7
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

1913578:LPB140 RS08650
gene id: 1913578:LPB140_RS08650
uniprot id: A0A1L3JCI0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

1913578:LPB140 RS07275
gene id: 1913578:LPB140_RS07275
uniprot id: A0A1L3JBW0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S24 family.
messages: Homodimer.
messages: Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.

1913578:LPB140 RS05420
gene id: 1913578:LPB140_RS05420
uniprot id: A0A1L3JEQ6
names: Cofactor
names: Similarity
messages: Belongs to the carotenoid oxygenase family.
messages: Binds 1 Fe(2+) ion per subunit.

1913578:LPB140 RS05480
gene id: 1913578:LPB140_RS05480
uniprot id: A0A1L3JB23
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Cytoplasm
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
messages: The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.

1913578:LPB140 RS03150
gene id: 1913578:LPB140_RS03150
uniprot id: A0A1L3JA20
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP H family.
messages: Cell inner membrane
messages: Membrane

1913578:LPB140 RS11590
gene id: 1913578:LPB140_RS11590
uniprot id: A0A1L3JDT8
names: Cofactor
names: Similarity
messages: Belongs to the RimK family.
messages: Binds 2 magnesium or manganese ions per subunit.

1913578:LPB140 RS00715
gene id: 1913578:LPB140_RS00715
uniprot id: A0A1L3J910
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

1913578:LPB140 RS05230
gene id: 1913578:LPB140_RS05230
uniprot id: A0A1L3JB70
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1913578:LPB140 RS09965
gene id: 1913578:LPB140_RS09965
uniprot id: A0A1L3JD37
names: Function
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.
messages: DNA-dependent ATPase that plays important roles in cellular responses to stalled DNA replication processes.

1913578:LPB140 RS08510
gene id: 1913578:LPB140_RS08510
uniprot id: A0A1L3JCE7
names: Caution
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1913578:LPB140 RS03890
gene id: 1913578:LPB140_RS03890
uniprot id: A0A1L3JAC8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-3 family.
messages: Cytoplasm
messages: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.
messages: Monomer.

1913578:LPB140 RS01100
gene id: 1913578:LPB140_RS01100
uniprot id: A0A1L3J992
names: Function
names: Similarity
messages: Belongs to the polysaccharide deacetylase family.
messages: Is involved in generating a small heat-stable compound (Nod), an acylated oligomer of N-acetylglucosamine, that stimulates mitosis in various plant protoplasts.

1913578:LPB140 RS04215
gene id: 1913578:LPB140_RS04215
uniprot id: A0A1L3JAJ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

1913578:LPB140 RS02940
gene id: 1913578:LPB140_RS02940
uniprot id: A0A1L3J9Y3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

1913578:LPB140 RS10195
gene id: 1913578:LPB140_RS10195
uniprot id: A0A1L3JD78
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

1913578:LPB140 RS07140
gene id: 1913578:LPB140_RS07140
uniprot id: A0A1L3JBT2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 3 family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1913578:LPB140 RS09435
gene id: 1913578:LPB140_RS09435
uniprot id: A0A1L3JCV7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

1913578:LPB140 RS09280
gene id: 1913578:LPB140_RS09280
uniprot id: A0A1L3JCU0
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

1913578:LPB140 RS10130
gene id: 1913578:LPB140_RS10130
uniprot id: A0A1L3JF65
names: Similarity
messages: Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family.

1913578:LPB140 RS06195
gene id: 1913578:LPB140_RS06195
uniprot id: A0A1L3JBD8
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

1913578:LPB140 RS02265
gene id: 1913578:LPB140_RS02265
uniprot id: A0A1L3J9T3
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

1913578:LPB140 RS05750
gene id: 1913578:LPB140_RS05750
uniprot id: A0A1L3JB57
names: Similarity
messages: Belongs to the CcdB toxin family.

1913578:LPB140 RS06450
gene id: 1913578:LPB140_RS06450
uniprot id: A0A1L3JBL0
names: Cofactor
messages: Can also use Mn(2+) ion.

1913578:LPB140 RS07655
gene id: 1913578:LPB140_RS07655
uniprot id: A0A1L3JC29
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

1913578:LPB140 RS00600
gene id: 1913578:LPB140_RS00600
uniprot id: A0A1L3J8X7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

1913578:LPB140 RS04420
gene id: 1913578:LPB140_RS04420
uniprot id: A0A1L3JAL8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

1913578:LPB140 RS08805
gene id: 1913578:LPB140_RS08805
uniprot id: A0A1L3JCJ7
names: Similarity
messages: Belongs to the LacAB/RpiB family.

1913578:LPB140 RS11620
gene id: 1913578:LPB140_RS11620
uniprot id: A0A1L3JDV3
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

1913578:LPB140 RS03255
gene id: 1913578:LPB140_RS03255
uniprot id: A0A1L3JA45
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1913578:LPB140 RS04865
gene id: 1913578:LPB140_RS04865
uniprot id: A0A1L3JAU1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

1913578:LPB140 RS10480
gene id: 1913578:LPB140_RS10480
uniprot id: A0A1L3JDB8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VirD4/TraG family.
messages: Membrane

1913578:LPB140 RS07620
gene id: 1913578:LPB140_RS07620
uniprot id: A0A1L3JC26
names: Similarity
messages: Belongs to the alanine racemase family.

1913578:LPB140 RS03875
gene id: 1913578:LPB140_RS03875
uniprot id: A0A1L3JAD3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Membrane

1913578:LPB140 RS01055
gene id: 1913578:LPB140_RS01055
uniprot id: A0A1L3J964
names: Similarity
messages: Belongs to the HpcH/HpaI aldolase family.

1913578:LPB140 RS07720
gene id: 1913578:LPB140_RS07720
uniprot id: A0A1L3JC34
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. FHS transporter (TC 2.A.1.7) family.
messages: Cell inner membrane
messages: Intake of glucose and galactose.
messages: Membrane

1913578:LPB140 RS08280
gene id: 1913578:LPB140_RS08280
uniprot id: A0A1L3JCB9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates guanosine-37 in various tRNAs.

1913578:LPB140 RS05255
gene id: 1913578:LPB140_RS05255
uniprot id: A0A1L3JAZ4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

1913578:LPB140 RS10090
gene id: 1913578:LPB140_RS10090
uniprot id: A0A1L3JDA2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome b560 family.
messages: Membrane
messages: Membrane-anchoring subunit of succinate dehydrogenase (SDH).
messages: Part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur protein, plus two membrane-anchoring proteins, SdhC and SdhD. The complex can form homotrimers.
messages: The heme is bound between the two transmembrane subunits.

1913578:LPB140 RS01300
gene id: 1913578:LPB140_RS01300
uniprot id: A0A1L3J991
names: Similarity
messages: Belongs to the cytochrome P450 family.

1913578:LPB140 RS04510
gene id: 1913578:LPB140_RS04510
uniprot id: A0A1L3JAM2
names: Subcellular Location Annotation
messages: Membrane

1913578:LPB140 RS11830
gene id: 1913578:LPB140_RS11830
uniprot id: A0A1L3JDZ9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Monomer.
messages: Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl-glutathione to form glutathione and D-lactic acid.

1913578:LPB140 RS05070
gene id: 1913578:LPB140_RS05070
uniprot id: A0A1L3JB36
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family.
messages: Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate.
messages: Cell inner membrane

1913578:LPB140 RS11005
gene id: 1913578:LPB140_RS11005
uniprot id: A0A1L3JDK4
names: Similarity
messages: Belongs to the serine/threonine dehydratase family.

1913578:LPB140 RS07390
gene id: 1913578:LPB140_RS07390
uniprot id: A0A1L3JBY2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1913578:LPB140 RS04665
gene id: 1913578:LPB140_RS04665
uniprot id: A0A1L3JAQ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Membrane

1913578:LPB140 RS01940
gene id: 1913578:LPB140_RS01940
uniprot id: A0A1L3J9I3
names: Function
names: Similarity
messages: Belongs to the dihydrofolate reductase family.
messages: Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.

1913578:LPB140 RS00065
gene id: 1913578:LPB140_RS00065
uniprot id: A0A1L3J8R3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

1913578:LPB140 RS12070
gene id: 1913578:LPB140_RS12070
uniprot id: A0A1L3JE24
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.

1913578:LPB140 RS10260
gene id: 1913578:LPB140_RS10260
uniprot id: A0A1L3JD62
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 2 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

1913578:LPB140 RS02765
gene id: 1913578:LPB140_RS02765
uniprot id: A0A1L3JA28
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1913578:LPB140 RS09485
gene id: 1913578:LPB140_RS09485
uniprot id: A0A1L3JCW8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane
messages: Membrane

1913578:LPB140 RS06860
gene id: 1913578:LPB140_RS06860
uniprot id: A0A1L3JBN5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0). The b'-subunit is a diverged and duplicated form of b found in plants and photosynthetic bacteria.
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

1913578:LPB140 RS03950
gene id: 1913578:LPB140_RS03950
uniprot id: A0A1L3JAE3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily.
messages: Catalyzes the oxidation of L-aspartate to iminoaspartate.
messages: Cytoplasm

1913578:LPB140 RS00330
gene id: 1913578:LPB140_RS00330
uniprot id: A0A1L3J8V5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Cell inner membrane
messages: Membrane

1913578:LPB140 RS01990
gene id: 1913578:LPB140_RS01990
uniprot id: A0A1L3J9K3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

1913578:LPB140 RS12050
gene id: 1913578:LPB140_RS12050
uniprot id: A0A1L3JE16
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

1913578:LPB140 RS03565
gene id: 1913578:LPB140_RS03565
uniprot id: A0A1L3JA79
names: Subcellular Location Annotation
messages: Membrane

1913578:LPB140 RS03290
gene id: 1913578:LPB140_RS03290
uniprot id: A0A1L3JA44
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1913578:LPB140 RS01515
gene id: 1913578:LPB140_RS01515
uniprot id: A0A1L3JEA8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

1913578:LPB140 RS03835
gene id: 1913578:LPB140_RS03835
uniprot id: A0A1L3JAC6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Cytoplasm
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

1913578:LPB140 RS02410
gene id: 1913578:LPB140_RS02410
uniprot id: A0A1L3J9R4
names: Similarity
messages: Belongs to the glycosyl hydrolase 3 family.

1913578:LPB140 RS10970
gene id: 1913578:LPB140_RS10970
uniprot id: A0A1L3JFA3
names: Subcellular Location Annotation
messages: Secreted

1913578:LPB140 RS11900
gene id: 1913578:LPB140_RS11900
uniprot id: A0A1L3JE04
names: Similarity
messages: Belongs to the UPF0335 family.

1913578:LPB140 RS08595
gene id: 1913578:LPB140_RS08595
uniprot id: A0A1L3JCG7
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphatidylserine decarboxylase family. PSD-A subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
messages: Cell membrane
messages: Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain.

1913578:LPB140 RS04310
gene id: 1913578:LPB140_RS04310
uniprot id: A0A1L3JEK1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

1913578:LPB140 RS11855
gene id: 1913578:LPB140_RS11855
uniprot id: A0A1L3JE01
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

1913578:LPB140 RS02435
gene id: 1913578:LPB140_RS02435
uniprot id: A0A1L3JEE8
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

1913578:LPB140 RS01905
gene id: 1913578:LPB140_RS01905
uniprot id: A0A1L3J9I6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

1913578:LPB140 RS00135
gene id: 1913578:LPB140_RS00135
uniprot id: A0A1L3J8S3
names: Function
messages: Multidrug efflux pump.

1913578:LPB140 RS07190
gene id: 1913578:LPB140_RS07190
uniprot id: A0A1L3JBS9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 23 kDa subunit family.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1913578:LPB140 RS04615
gene id: 1913578:LPB140_RS04615
uniprot id: A0A1L3JAP9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

1913578:LPB140 RS06870
gene id: 1913578:LPB140_RS06870
uniprot id: A0A1L3JBV5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

1913578:LPB140 RS11765
gene id: 1913578:LPB140_RS11765
uniprot id: A0A1L3JDZ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP12 family.
messages: Mitochondrion

1913578:LPB140 RS05205
gene id: 1913578:LPB140_RS05205
uniprot id: A0A1L3JEM6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

1913578:LPB140 RS01265
gene id: 1913578:LPB140_RS01265
uniprot id: A0A1L3J978
names: Function
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.

1913578:LPB140 RS08865
gene id: 1913578:LPB140_RS08865
uniprot id: A0A1L3JCM3
names: Similarity
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 5 (UDGb) family.

1913578:LPB140 RS06685
gene id: 1913578:LPB140_RS06685
uniprot id: A0A1L3JBT0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LemA family.
messages: Membrane

1913578:LPB140 RS10575
gene id: 1913578:LPB140_RS10575
uniprot id: A0A1L3JDE7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Lacks the C-terminal regulatory region which is replaced by HisZ.

1913578:LPB140 RS05210
gene id: 1913578:LPB140_RS05210
uniprot id: A0A1L3JB10
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

1913578:LPB140 RS04695
gene id: 1913578:LPB140_RS04695
uniprot id: A0A1L3JAQ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

1913578:LPB140 RS12030
gene id: 1913578:LPB140_RS12030
uniprot id: A0A1L3JE25
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

1913578:LPB140 RS02390
gene id: 1913578:LPB140_RS02390
uniprot id: A0A1L3J9S0
names: Function
names: Similarity
messages: Belongs to the NadC/ModD family.
messages: Involved in the catabolism of quinolinic acid (QA).

1913578:LPB140 RS00465
gene id: 1913578:LPB140_RS00465
uniprot id: A0A1L3JE69
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1913578:LPB140 RS11485
gene id: 1913578:LPB140_RS11485
uniprot id: A0A1L3JFB5
names: Similarity
messages: Belongs to the ArsC family.

1913578:LPB140 RS07310
gene id: 1913578:LPB140_RS07310
uniprot id: A0A1L3JBW2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Membrane

1913578:LPB140 RS01395
gene id: 1913578:LPB140_RS01395
uniprot id: A0A1L3J9E1
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

1913578:LPB140 RS02945
gene id: 1913578:LPB140_RS02945
uniprot id: A0A1L3JA60
names: Function
names: Subunit
messages: E1 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the decarboxylation of 2-oxoglutarate, the first step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).
messages: Homodimer. Part of the 2-oxoglutarate dehydrogenase (OGDH) complex composed of E1 (2-oxoglutarate dehydrogenase), E2 (dihydrolipoamide succinyltransferase) and E3 (dihydrolipoamide dehydrogenase); the complex contains multiple copies of the three enzymatic components (E1, E2 and E3).

1913578:LPB140 RS05630
gene id: 1913578:LPB140_RS05630
uniprot id: A0A1L3JB43
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins.

1913578:LPB140 RS10050
gene id: 1913578:LPB140_RS10050
uniprot id: A0A1L3JD66
names: Similarity
messages: Belongs to the aspartokinase family.

1913578:LPB140 RS01025
gene id: 1913578:LPB140_RS01025
uniprot id: A0A1L3J952
names: Similarity
messages: Belongs to the PrpD family.

1913578:LPB140 RS08395
gene id: 1913578:LPB140_RS08395
uniprot id: A0A1L3JCD9
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

1913578:LPB140 RS11040
gene id: 1913578:LPB140_RS11040
uniprot id: A0A1L3JDP4
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1913578:LPB140 RS09400
gene id: 1913578:LPB140_RS09400
uniprot id: A0A1L3JCU5
names: Function
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.

1913578:LPB140 RS10965
gene id: 1913578:LPB140_RS10965
uniprot id: A0A1L3JDM8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glutamine synthetase family.
messages: Catalyzes the ATP-dependent biosynthesis of glutamine from glutamate and ammonia.
messages: Cytoplasm
messages: Oligomer of 12 subunits arranged in the form of two hexagons.
messages: Oligomer of 12 subunits arranged in the form of two hexameric ring.

1913578:LPB140 RS11880
gene id: 1913578:LPB140_RS11880
uniprot id: A0A1L3JE23
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvC family.
messages: Binds 2 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer which binds Holliday junction (HJ) DNA. The HJ becomes 2-fold symmetrical on binding to RuvC with unstacked arms; it has a different conformation from HJ DNA in complex with RuvA. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair. Endonuclease that resolves HJ intermediates. Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction. The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'. Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange. HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

1913578:LPB140 RS06420
gene id: 1913578:LPB140_RS06420
uniprot id: A0A1L3JBP1
names: Subcellular Location Annotation
messages: Membrane

1913578:LPB140 RS05425
gene id: 1913578:LPB140_RS05425
uniprot id: A0A1L3JB30
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.

1913578:LPB140 RS01570
gene id: 1913578:LPB140_RS01570
uniprot id: A0A1L3J9D9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family.
messages: Membrane

1913578:LPB140 RS06560
gene id: 1913578:LPB140_RS06560
uniprot id: A0A1L3JBK1
names: Similarity
messages: Belongs to the polysaccharide synthase family.

1913578:LPB140 RS09050
gene id: 1913578:LPB140_RS09050
uniprot id: A0A1L3JCW4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

1913578:LPB140 RS00905
gene id: 1913578:LPB140_RS00905
uniprot id: A0A1L3J932
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ThiC family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
messages: Homodimer.

1913578:LPB140 RS11385
gene id: 1913578:LPB140_RS11385
uniprot id: A0A1L3JDR5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

1913578:LPB140 RS01420
gene id: 1913578:LPB140_RS01420
uniprot id: A0A1L3J9A5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEDS family. MrdB/RodA subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Peptidoglycan polymerase that is essential for cell wall elongation.

1913578:LPB140 RS06730
gene id: 1913578:LPB140_RS06730
uniprot id: A0A1L3JBL8
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

1913578:LPB140 RS08150
gene id: 1913578:LPB140_RS08150
uniprot id: A0A1L3JC82
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

1913578:LPB140 RS06300
gene id: 1913578:LPB140_RS06300
uniprot id: A0A1L3JEV5
names: Similarity
messages: Belongs to the asparagine synthetase family.

1913578:LPB140 RS00310
gene id: 1913578:LPB140_RS00310
uniprot id: A0A1L3J8V1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1913578:LPB140 RS07465
gene id: 1913578:LPB140_RS07465
uniprot id: A0A1L3JBZ4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer.

1913578:LPB140 RS02330
gene id: 1913578:LPB140_RS02330
uniprot id: A0A1L3JED4
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

1913578:LPB140 RS10045
gene id: 1913578:LPB140_RS10045
uniprot id: A0A1L3JD44
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily. UbiG/COQ3 family.
messages: O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway.

1913578:LPB140 RS04655
gene id: 1913578:LPB140_RS04655
uniprot id: A0A1L3JAQ0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

1913578:LPB140 RS09095
gene id: 1913578:LPB140_RS09095
uniprot id: A0A1L3JF22
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

1913578:LPB140 RS07860
gene id: 1913578:LPB140_RS07860
uniprot id: A0A1L3JC55
names: Similarity
messages: Belongs to the ribosome association toxin RatA family.

1913578:LPB140 RS05620
gene id: 1913578:LPB140_RS05620
uniprot id: A0A1L3JB39
names: Similarity
messages: Belongs to the glycosyl hydrolase 25 family.

1913578:LPB140 RS00700
gene id: 1913578:LPB140_RS00700
uniprot id: A0A1L3J903
names: Caution
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1913578:LPB140 RS01245
gene id: 1913578:LPB140_RS01245
uniprot id: A0A1L3JEH8
names: Subcellular Location Annotation
messages: Membrane

1913578:LPB140 RS07925
gene id: 1913578:LPB140_RS07925
uniprot id: A0A1L3JF03
names: Similarity
messages: Belongs to the universal stress protein A family.

1913578:LPB140 RS07920
gene id: 1913578:LPB140_RS07920
uniprot id: A0A1L3JCD6
names: Subcellular Location Annotation
messages: Membrane

1913578:LPB140 RS10590
gene id: 1913578:LPB140_RS10590
uniprot id: A0A1L3JDM7
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1913578:LPB140 RS06550
gene id: 1913578:LPB140_RS06550
uniprot id: A0A1L3JBH1
names: Similarity
messages: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.

1913578:LPB140 RS03995
gene id: 1913578:LPB140_RS03995
uniprot id: A0A1L3JAE8
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.

1913578:LPB140 RS08835
gene id: 1913578:LPB140_RS08835
uniprot id: A0A1L3JCL5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

1913578:LPB140 RS10825
gene id: 1913578:LPB140_RS10825
uniprot id: A0A1L3JDI6
names: Function
names: Similarity
messages: Belongs to the polysaccharide deacetylase family.
messages: Is involved in generating a small heat-stable compound (Nod), an acylated oligomer of N-acetylglucosamine, that stimulates mitosis in various plant protoplasts.

1913578:LPB140 RS08355
gene id: 1913578:LPB140_RS08355
uniprot id: A0A1L3JCD3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 51 family.
messages: Cell inner membrane
messages: Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors.

1913578:LPB140 RS03885
gene id: 1913578:LPB140_RS03885
uniprot id: A0A1L3JAE4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SURF1 family.
messages: Cell membrane

1913578:LPB140 RS02060
gene id: 1913578:LPB140_RS02060
uniprot id: A0A1L3J9M0
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

1913578:LPB140 RS02745
gene id: 1913578:LPB140_RS02745
uniprot id: A0A1L3J9Y2
names: Similarity
messages: Belongs to the OmpW/AlkL family.

1913578:LPB140 RS06355
gene id: 1913578:LPB140_RS06355
uniprot id: A0A1L3JBF2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

1913578:LPB140 RS01250
gene id: 1913578:LPB140_RS01250
uniprot id: A0A1L3J988
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0324 family.
messages: Membrane

1913578:LPB140 RS04225
gene id: 1913578:LPB140_RS04225
uniprot id: A0A1L3JAH8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

1913578:LPB140 RS07670
gene id: 1913578:LPB140_RS07670
uniprot id: A0A1L3JC27
names: Similarity
messages: Belongs to the DNA polymerase type-Y family.

1913578:LPB140 RS06280
gene id: 1913578:LPB140_RS06280
uniprot id: A0A1L3JBE3
names: Function
names: Similarity
messages: Belongs to the polysaccharide deacetylase family.
messages: Is involved in generating a small heat-stable compound (Nod), an acylated oligomer of N-acetylglucosamine, that stimulates mitosis in various plant protoplasts.

1913578:LPB140 RS01130
gene id: 1913578:LPB140_RS01130
uniprot id: A0A1L3J974
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 1 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

1913578:LPB140 RS10030
gene id: 1913578:LPB140_RS10030
uniprot id: A0A1L3JD54
names: Similarity
messages: Belongs to the glutamate synthase family.

1913578:LPB140 RS09645
gene id: 1913578:LPB140_RS09645
uniprot id: A0A1L3JCY2
names: Subcellular Location Annotation
messages: Membrane

1913578:LPB140 RS09930
gene id: 1913578:LPB140_RS09930
uniprot id: A0A1L3JD16
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Fur family.
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.

1913578:LPB140 RS03795
gene id: 1913578:LPB140_RS03795
uniprot id: A0A1L3JAB7
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

1913578:LPB140 RS00120
gene id: 1913578:LPB140_RS00120
uniprot id: A0A1L3J8Q1
names: Subcellular Location Annotation
messages: Membrane

1913578:LPB140 RS08190
gene id: 1913578:LPB140_RS08190
uniprot id: A0A1L3JCB4
names: Similarity
messages: Belongs to the thioredoxin family.

1913578:LPB140 RS06380
gene id: 1913578:LPB140_RS06380
uniprot id: A0A1L3JEU8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

1913578:LPB140 RS06150
gene id: 1913578:LPB140_RS06150
uniprot id: A0A1L3JBC3
names: Similarity
messages: Belongs to the SAICAR synthetase family.

1913578:LPB140 RS11580
gene id: 1913578:LPB140_RS11580
uniprot id: A0A1L3JDW8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.

1913578:LPB140 RS08080
gene id: 1913578:LPB140_RS08080
uniprot id: A0A1L3JC89
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

1913578:LPB140 RS04405
gene id: 1913578:LPB140_RS04405
uniprot id: A0A1L3JAM6
names: Similarity
messages: Belongs to the class-A beta-lactamase family.

1913578:LPB140 RS07155
gene id: 1913578:LPB140_RS07155
uniprot id: A0A1L3JBW7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 49 kDa subunit family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1913578:LPB140 RS11995
gene id: 1913578:LPB140_RS11995
uniprot id: A0A1L3JE08
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I fumarase family.
messages: Catalyzes the reversible hydration of fumarate to (S)-malate.
messages: Homodimer.

1913578:LPB140 RS09240
gene id: 1913578:LPB140_RS09240
uniprot id: A0A1L3JF35
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamA family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

1913578:LPB140 RS00730
gene id: 1913578:LPB140_RS00730
uniprot id: A0A1L3J8Z9
names: Function
names: Similarity
messages: Belongs to the bacterioferritin family.
messages: Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex.

1913578:LPB140 RS01500
gene id: 1913578:LPB140_RS01500
uniprot id: A0A1L3J999
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1913578:LPB140 RS05465
gene id: 1913578:LPB140_RS05465
uniprot id: A0A1L3JB13
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

1913578:LPB140 RS11655
gene id: 1913578:LPB140_RS11655
uniprot id: A0A1L3JDX1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

1913578:LPB140 RS06115
gene id: 1913578:LPB140_RS06115
uniprot id: A0A1L3JBC1
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1913578:LPB140 RS05260
gene id: 1913578:LPB140_RS05260
uniprot id: A0A1L3JB08
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

1913578:LPB140 RS04240
gene id: 1913578:LPB140_RS04240
uniprot id: A0A1L3JAI7
names: Cofactor
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.

1913578:LPB140 RS09330
gene id: 1913578:LPB140_RS09330
uniprot id: A0A1L3JCY3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.
messages: Membrane

1913578:LPB140 RS07200
gene id: 1913578:LPB140_RS07200
uniprot id: A0A1L3JBS8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1913578:LPB140 RS07850
gene id: 1913578:LPB140_RS07850
uniprot id: A0A1L3JC66
names: Caution
names: Function
names: Similarity
messages: Belongs to the IspF family.
messages: Bifunctional enzyme that catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF).
messages: In the C-terminal section; belongs to the IspF family.
messages: In the N-terminal section; belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1913578:LPB140 RS02260
gene id: 1913578:LPB140_RS02260
uniprot id: A0A1L3J9L9
names: Similarity
messages: Belongs to the YggT family.

1913578:LPB140 RS05770
gene id: 1913578:LPB140_RS05770
uniprot id: A0A1L3JEV0
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2).

1913578:LPB140 RS01945
gene id: 1913578:LPB140_RS01945
uniprot id: A0A1L3J9J2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)- to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Homodimer.

1913578:LPB140 RS01105
gene id: 1913578:LPB140_RS01105
uniprot id: A0A1L3J960
names: Function
names: Similarity
messages: Belongs to the polysaccharide deacetylase family.
messages: Is involved in generating a small heat-stable compound (Nod), an acylated oligomer of N-acetylglucosamine, that stimulates mitosis in various plant protoplasts.

1913578:LPB140 RS00525
gene id: 1913578:LPB140_RS00525
uniprot id: A0A1L3J8X2
names: Function
names: Similarity
messages: Belongs to the MoaB/Mog family.
messages: May be involved in the biosynthesis of molybdopterin.

1913578:LPB140 RS11065
gene id: 1913578:LPB140_RS11065
uniprot id: A0A1L3JDL0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

1913578:LPB140 RS04080
gene id: 1913578:LPB140_RS04080
uniprot id: A0A1L3JAH2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.

1913578:LPB140 RS11225
gene id: 1913578:LPB140_RS11225
uniprot id: A0A1L3JDP9
names: Similarity
messages: In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family.

1913578:LPB140 RS10485
gene id: 1913578:LPB140_RS10485
uniprot id: A0A1L3JDD4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VirD4/TraG family.
messages: Membrane

1913578:LPB140 RS10740
gene id: 1913578:LPB140_RS10740
uniprot id: A0A1L3JDI0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1913578:LPB140 RS02820
gene id: 1913578:LPB140_RS02820
uniprot id: A0A1L3JA39
names: Similarity
messages: Belongs to the HpcH/HpaI aldolase family.

1913578:LPB140 RS07020
gene id: 1913578:LPB140_RS07020
uniprot id: A0A1L3JBU3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1913578:LPB140 RS01365
gene id: 1913578:LPB140_RS01365
uniprot id: A0A1L3J9A8
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

1913578:LPB140 RS06075
gene id: 1913578:LPB140_RS06075
uniprot id: A0A1L3JBD2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

1913578:LPB140 RS00405
gene id: 1913578:LPB140_RS00405
uniprot id: A0A1L3JE72
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

1913578:LPB140 RS01605
gene id: 1913578:LPB140_RS01605
uniprot id: A0A1L3J9E8
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.

1913578:LPB140 RS07380
gene id: 1913578:LPB140_RS07380
uniprot id: A0A1L3JBX2
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.

1913578:LPB140 RS00660
gene id: 1913578:LPB140_RS00660
uniprot id: A0A1L3J8Y8
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1913578:LPB140 RS11865
gene id: 1913578:LPB140_RS11865
uniprot id: A0A1L3JE19
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

1913578:LPB140 RS03200
gene id: 1913578:LPB140_RS03200
uniprot id: A0A1L3JA35
names: Similarity
messages: Belongs to the FrmR/RcnR family.

1913578:LPB140 RS05615
gene id: 1913578:LPB140_RS05615
uniprot id: A0A1L3JB34
names: Function
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.

1913578:LPB140 RS08945
gene id: 1913578:LPB140_RS08945
uniprot id: A0A1L3JCL0
names: Similarity
messages: Belongs to the argonaute family. Long pAgo subfamily.

1913578:LPB140 RS00880
gene id: 1913578:LPB140_RS00880
uniprot id: A0A1L3J916
names: Similarity
messages: Belongs to the lycopene cyclase family.

1913578:LPB140 RS08290
gene id: 1913578:LPB140_RS08290
uniprot id: A0A1L3JCC1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

1913578:LPB140 RS02990
gene id: 1913578:LPB140_RS02990
uniprot id: A0A1L3JA08
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

1913578:LPB140 RS06340
gene id: 1913578:LPB140_RS06340
uniprot id: A0A1L3JBN1
names: Similarity
messages: Belongs to the prokaryotic GSH synthase family.

1913578:LPB140 RS07315
gene id: 1913578:LPB140_RS07315
uniprot id: A0A1L3JBZ5
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1913578:LPB140 RS12150
gene id: 1913578:LPB140_RS12150
uniprot id: A0A1L3JE49
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm

1913578:LPB140 RS08480
gene id: 1913578:LPB140_RS08480
uniprot id: A0A1L3JCF3
names: Cofactor
names: Similarity
messages: Belongs to the DNA photolyase family.
messages: Binds 1 FAD per subunit.

1913578:LPB140 RS04200
gene id: 1913578:LPB140_RS04200
uniprot id: A0A1L3JAH9
names: Similarity
messages: Belongs to the Cob(I)alamin adenosyltransferase family.

1913578:LPB140 RS09355
gene id: 1913578:LPB140_RS09355
uniprot id: A0A1L3JCU8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial sugar transferase family.
messages: Membrane

1913578:LPB140 RS01205
gene id: 1913578:LPB140_RS01205
uniprot id: A0A1L3JE94
names: Cofactor
names: Function
messages: Accepts electrons from ETF and reduces ubiquinone.
messages: Binds 1 [4Fe-4S] cluster.

1913578:LPB140 RS06665
gene id: 1913578:LPB140_RS06665
uniprot id: A0A1L3JBK5
names: Function
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.

1913578:LPB140 RS07405
gene id: 1913578:LPB140_RS07405
uniprot id: A0A1L3JBW4
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. Nitrilase family.

1913578:LPB140 RS08430
gene id: 1913578:LPB140_RS08430
uniprot id: A0A1L3JCL4
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

1913578:LPB140 RS04315
gene id: 1913578:LPB140_RS04315
uniprot id: A0A1L3JAJ6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial histone-like protein family.
messages: Heterodimer of an alpha and a beta chain.
messages: This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.

1913578:LPB140 RS06590
gene id: 1913578:LPB140_RS06590
uniprot id: A0A1L3JEV7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YajC family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the SecDF-YidC-YajC translocase complex. The SecDF-YidC-YajC translocase forms a supercomplex with SecYEG, called the holo-translocon (HTL).
messages: The SecYEG-SecDF-YajC-YidC holo-translocon (HTL) protein secretase/insertase is a supercomplex required for protein secretion, insertion of proteins into membranes, and assembly of membrane protein complexes. While the SecYEG complex is essential for assembly of a number of proteins and complexes, the SecDF-YajC-YidC subcomplex facilitates these functions.

1913578:LPB140 RS11390
gene id: 1913578:LPB140_RS11390
uniprot id: A0A1L3JDU0
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1913578:LPB140 RS02585
gene id: 1913578:LPB140_RS02585
uniprot id: A0A1L3J9R7
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

1913578:LPB140 RS04375
gene id: 1913578:LPB140_RS04375
uniprot id: A0A1L3JAK7
names: Similarity
messages: Belongs to the peptidase M20A family. ArgE subfamily.

1913578:LPB140 RS06765
gene id: 1913578:LPB140_RS06765
uniprot id: A0A1L3JBM2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PNT beta subunit family.
messages: Cell inner membrane
messages: Membrane
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

1913578:LPB140 RS03710
gene id: 1913578:LPB140_RS03710
uniprot id: A0A1L3JAB2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TrbL/VirB6 family.
messages: Membrane

1913578:LPB140 RS10785
gene id: 1913578:LPB140_RS10785
uniprot id: A0A1L3JDH7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

1913578:LPB140 RS05535
gene id: 1913578:LPB140_RS05535
uniprot id: A0A1L3JB24
names: Similarity
messages: Belongs to the bacterial glucokinase family.

1913578:LPB140 RS02065
gene id: 1913578:LPB140_RS02065
uniprot id: A0A1L3J9L5
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

1913578:LPB140 RS10305
gene id: 1913578:LPB140_RS10305
uniprot id: A0A1L3JF70
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1913578:LPB140 RS11275
gene id: 1913578:LPB140_RS11275
uniprot id: A0A1L3JDP2
names: Cofactor
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.
messages: Probably binds two magnesium or manganese ions per subunit.

1913578:LPB140 RS11055
gene id: 1913578:LPB140_RS11055
uniprot id: A0A1L3JDM5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1913578:LPB140 RS06725
gene id: 1913578:LPB140_RS06725
uniprot id: A0A1L3JBP3
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

1913578:LPB140 RS01880
gene id: 1913578:LPB140_RS01880
uniprot id: A0A1L3J9I4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

1913578:LPB140 RS09260
gene id: 1913578:LPB140_RS09260
uniprot id: A0A1L3JCS7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.

1913578:LPB140 RS05360
gene id: 1913578:LPB140_RS05360
uniprot id: A0A1L3JEN7
names: Subunit
messages: Homotetramer.

1913578:LPB140 RS11300
gene id: 1913578:LPB140_RS11300
uniprot id: A0A1L3JDQ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0053 family. Hemolysin C subfamily.
messages: Membrane

1913578:LPB140 RS11985
gene id: 1913578:LPB140_RS11985
uniprot id: A0A1L3JE12
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.
messages: Binds 2 iron ions per subunit.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

1913578:LPB140 RS11650
gene id: 1913578:LPB140_RS11650
uniprot id: A0A1L3JDY8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

1913578:LPB140 RS02725
gene id: 1913578:LPB140_RS02725
uniprot id: A0A1L3J9V7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CcoP / FixP family.
messages: Binds 2 heme C groups per subunit.
messages: C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex.
messages: Cell inner membrane
messages: Component of the cbb3-type cytochrome c oxidase.
messages: Membrane

1913578:LPB140 RS08620
gene id: 1913578:LPB140_RS08620
uniprot id: A0A1L3JCI1
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

1913578:LPB140 RS12015
gene id: 1913578:LPB140_RS12015
uniprot id: A0A1L3JE06
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PEPCase type 1 family.
messages: Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.
messages: Homotetramer.

1913578:LPB140 RS07165
gene id: 1913578:LPB140_RS07165
uniprot id: A0A1L3JBU0
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

1913578:LPB140 RS04470
gene id: 1913578:LPB140_RS04470
uniprot id: A0A1L3JAN7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CN hydrolase family. Apolipoprotein N-acyltransferase subfamily.
messages: Catalyzes the phospholipid dependent N-acylation of the N-terminal cysteine of apolipoprotein, the last step in lipoprotein maturation.
messages: Cell membrane
messages: Membrane

1913578:LPB140 RS10930
gene id: 1913578:LPB140_RS10930
uniprot id: A0A1L3JDS6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
messages: Cell membrane
messages: Monomer.

1913578:LPB140 RS08625
gene id: 1913578:LPB140_RS08625
uniprot id: A0A1L3JCF7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

1913578:LPB140 RS06920
gene id: 1913578:LPB140_RS06920
uniprot id: A0A1L3JBQ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell inner membrane
messages: Membrane

1913578:LPB140 RS11670
gene id: 1913578:LPB140_RS11670
uniprot id: A0A1L3JE37
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

1913578:LPB140 RS04835
gene id: 1913578:LPB140_RS04835
uniprot id: A0A1L3JAS8
names: Cofactor
names: Similarity
messages: Belongs to the class-II DAHP synthase family.
messages: Binds 1 divalent cation per subunit. The enzyme is active with manganese, cobalt or cadmium ions.

1913578:LPB140 RS10315
gene id: 1913578:LPB140_RS10315
uniprot id: A0A1L3JDH9
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1913578:LPB140 RS08685
gene id: 1913578:LPB140_RS08685
uniprot id: A0A1L3JCG9
names: Function
names: PTM
names: Similarity
messages: An intermediate of this reaction is the autophosphorylated ppk in which a phosphate is covalently linked to a histidine residue through a N-P bond.
messages: Belongs to the polyphosphate kinase 1 (PPK1) family.
messages: Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP).

1913578:LPB140 RS11635
gene id: 1913578:LPB140_RS11635
uniprot id: A0A1L3JDX9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

1913578:LPB140 RS02955
gene id: 1913578:LPB140_RS02955
uniprot id: A0A1L3J9Z0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 1 lipoyl cofactor covalently.
messages: E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).

1913578:LPB140 RS06800
gene id: 1913578:LPB140_RS06800
uniprot id: A0A1L3JBU5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

1913578:LPB140 RS08170
gene id: 1913578:LPB140_RS08170
uniprot id: A0A1L3JCD8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

1913578:LPB140 RS06690
gene id: 1913578:LPB140_RS06690
uniprot id: A0A1L3JBJ1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscL family.
messages: Cell inner membrane
messages: Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
messages: Homopentamer.
messages: Membrane

1913578:LPB140 RS06905
gene id: 1913578:LPB140_RS06905
uniprot id: A0A1L3JBS3
names: Similarity
messages: Belongs to the class-A beta-lactamase family.

1913578:LPB140 RS12010
gene id: 1913578:LPB140_RS12010
uniprot id: A0A1L3JE27
names: Similarity
messages: Belongs to the cytochrome P450 family.

1913578:LPB140 RS00495
gene id: 1913578:LPB140_RS00495
uniprot id: A0A1L3J8Y6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Nitrate/nitrite porter (TC 2.A.1.8) family.
messages: Membrane

1913578:LPB140 RS02795
gene id: 1913578:LPB140_RS02795
uniprot id: A0A1L3J9Z6
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1913578:LPB140 RS02105
gene id: 1913578:LPB140_RS02105
uniprot id: A0A1L3JEA5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family.
messages: Cytoplasm
messages: Homotrimer.

1913578:LPB140 RS11680
gene id: 1913578:LPB140_RS11680
uniprot id: A0A1L3JDX2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

1913578:LPB140 RS05330
gene id: 1913578:LPB140_RS05330
uniprot id: A0A1L3JB19
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MlaE permease family.
messages: Cell inner membrane
messages: Could be part of an ABC transporter complex.
messages: Membrane

1913578:LPB140 RS02515
gene id: 1913578:LPB140_RS02515
uniprot id: A0A1L3J9X4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1913578:LPB140 RS01575
gene id: 1913578:LPB140_RS01575
uniprot id: A0A1L3JE81
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.
messages: This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.

1913578:LPB140 RS07625
gene id: 1913578:LPB140_RS07625
uniprot id: A0A1L3JC84
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1913578:LPB140 RS10295
gene id: 1913578:LPB140_RS10295
uniprot id: A0A1L3JD85
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1913578:LPB140 RS06205
gene id: 1913578:LPB140_RS06205
uniprot id: A0A1L3JBK2
names: Function
names: Similarity
messages: Belongs to the transglycosylase MltG family.
messages: Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.

1913578:LPB140 RS06390
gene id: 1913578:LPB140_RS06390
uniprot id: A0A1L3JEU4
names: Similarity
messages: Belongs to the peptidase S41A family.

1913578:LPB140 RS07610
gene id: 1913578:LPB140_RS07610
uniprot id: A0A1L3JC11
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

1913578:LPB140 RS00125
gene id: 1913578:LPB140_RS00125
uniprot id: A0A1L3J8R0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Homodimer. Forms a membrane-associated complex with FtsX.
messages: Part of the ABC transporter FtsEX involved in cellular division. Important for assembly or stability of the septal ring.

1913578:LPB140 RS07025
gene id: 1913578:LPB140_RS07025
uniprot id: A0A1L3JBR9
names: Function
names: Similarity
messages: Belongs to the BCKDHA family.
messages: The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3).

1913578:LPB140 RS06125
gene id: 1913578:LPB140_RS06125
uniprot id: A0A1L3JBC2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily.
messages: Cell inner membrane
messages: Involved in the import of queuosine (Q) precursors, required for Q precursor salvage.

1913578:LPB140 RS09495
gene id: 1913578:LPB140_RS09495
uniprot id: A0A1L3JCW7
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1913578:LPB140 RS02670
gene id: 1913578:LPB140_RS02670
uniprot id: A0A1L3J9U7
names: Subcellular Location Annotation
messages: Nucleus

1913578:LPB140 RS06305
gene id: 1913578:LPB140_RS06305
uniprot id: A0A1L3JBG7
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1913578:LPB140 RS01370
gene id: 1913578:LPB140_RS01370
uniprot id: A0A1L3J9B0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

1913578:LPB140 RS06135
gene id: 1913578:LPB140_RS06135
uniprot id: A0A1L3JEV2
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

1913578:LPB140 RS06335
gene id: 1913578:LPB140_RS06335
uniprot id: A0A1L3JBF5
names: Similarity
messages: Belongs to the UPF0102 family.

1913578:LPB140 RS06720
gene id: 1913578:LPB140_RS06720
uniprot id: A0A1L3JBM1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

1913578:LPB140 RS09055
gene id: 1913578:LPB140_RS09055
uniprot id: A0A1L3JCQ3
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

1913578:LPB140 RS09110
gene id: 1913578:LPB140_RS09110
uniprot id: A0A1L3JCQ8
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1913578:LPB140 RS01610
gene id: 1913578:LPB140_RS01610
uniprot id: A0A1L3J9F8
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1913578:LPB140 RS06185
gene id: 1913578:LPB140_RS06185
uniprot id: A0A1L3JBD3
names: Similarity
messages: Belongs to the fabD family.

1913578:LPB140 RS05235
gene id: 1913578:LPB140_RS05235
uniprot id: A0A1L3JAY5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DoxX family.
messages: Membrane

1913578:LPB140 RS09100
gene id: 1913578:LPB140_RS09100
uniprot id: A0A1L3JCS4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

1913578:LPB140 RS11925
gene id: 1913578:LPB140_RS11925
uniprot id: A0A1L3JE28
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1913578:LPB140 RS09670
gene id: 1913578:LPB140_RS09670
uniprot id: A0A1L3JCZ4
names: Function
names: Similarity
messages: Belongs to the folylpolyglutamate synthase family.
messages: Functions in two distinct reactions of the de novo folate biosynthetic pathway. Catalyzes the addition of a glutamate residue to dihydropteroate (7,8-dihydropteroate or H2Pte) to form dihydrofolate (7,8-dihydrofolate monoglutamate or H2Pte-Glu). Also catalyzes successive additions of L-glutamate to tetrahydrofolate or 10-formyltetrahydrofolate or 5,10-methylenetetrahydrofolate, leading to folylpolyglutamate derivatives.

1913578:LPB140 RS05440
gene id: 1913578:LPB140_RS05440
uniprot id: A0A1L3JEX9
names: Function
names: Similarity
messages: Belongs to the PurU family.
messages: Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).

1913578:LPB140 RS04245
gene id: 1913578:LPB140_RS04245
uniprot id: A0A1L3JAQ4
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1913578:LPB140 RS02395
gene id: 1913578:LPB140_RS02395
uniprot id: A0A1L3J9P1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the quinolinate synthase family. Type 2 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
messages: Cytoplasm

1913578:LPB140 RS00445
gene id: 1913578:LPB140_RS00445
uniprot id: A0A1L3J8X1
names: Similarity
messages: Belongs to the ArsC family.

1913578:LPB140 RS03825
gene id: 1913578:LPB140_RS03825
uniprot id: A0A1L3JEK0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

1913578:LPB140 RS08820
gene id: 1913578:LPB140_RS08820
uniprot id: A0A1L3JCL1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

1913578:LPB140 RS05700
gene id: 1913578:LPB140_RS05700
uniprot id: A0A1L3JES5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

1913578:LPB140 RS10635
gene id: 1913578:LPB140_RS10635
uniprot id: A0A1L3JDD5
names: Similarity
messages: Belongs to the BolA/IbaG family.

1913578:LPB140 RS11610
gene id: 1913578:LPB140_RS11610
uniprot id: A0A1L3JDV7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

1913578:LPB140 RS08350
gene id: 1913578:LPB140_RS08350
uniprot id: A0A1L3JCH0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoH subfamily.
messages: Cytoplasm
messages: Interacts with the RNA polymerase core enzyme.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes.

1913578:LPB140 RS04925
gene id: 1913578:LPB140_RS04925
uniprot id: A0A1L3JAV2
names: Similarity
messages: Belongs to the sodium:galactoside symporter (TC 2.A.2) family.

1913578:LPB140 RS12055
gene id: 1913578:LPB140_RS12055
uniprot id: A0A1L3JE59
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm

1913578:LPB140 RS11045
gene id: 1913578:LPB140_RS11045
uniprot id: A0A1L3JDM4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

1913578:LPB140 RS11940
gene id: 1913578:LPB140_RS11940
uniprot id: A0A1L3JE33
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

1913578:LPB140 RS11730
gene id: 1913578:LPB140_RS11730
uniprot id: A0A1L3JDY0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

1913578:LPB140 RS11095
gene id: 1913578:LPB140_RS11095
uniprot id: A0A1L3JDQ3
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

1913578:LPB140 RS02225
gene id: 1913578:LPB140_RS02225
uniprot id: A0A1L3J9N7
names: Similarity
messages: Belongs to the FGGY kinase family.

1913578:LPB140 RS11510
gene id: 1913578:LPB140_RS11510
uniprot id: A0A1L3JDV6
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

1913578:LPB140 RS11230
gene id: 1913578:LPB140_RS11230
uniprot id: A0A1L3JDX3
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1913578:LPB140 RS08700
gene id: 1913578:LPB140_RS08700
uniprot id: A0A1L3JCJ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

1913578:LPB140 RS08980
gene id: 1913578:LPB140_RS08980
uniprot id: A0A1L3JCV3
names: Similarity
messages: Belongs to the Nudix hydrolase family.

1913578:LPB140 RS06520
gene id: 1913578:LPB140_RS06520
uniprot id: A0A1L3JBI3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

1913578:LPB140 RS05395
gene id: 1913578:LPB140_RS05395
uniprot id: A0A1L3JB05
names: Similarity
messages: Belongs to the glycosyl hydrolase 10 (cellulase F) family.

1913578:LPB140 RS07450
gene id: 1913578:LPB140_RS07450
uniprot id: A0A1L3JC50
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsY family.
messages: Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
messages: Cell membrane
messages: Probably interacts with PlsX.

1913578:LPB140 RS08525
gene id: 1913578:LPB140_RS08525
uniprot id: A0A1L3JCG4
names: Similarity
messages: Belongs to the band 7/mec-2 family.

1913578:LPB140 RS10140
gene id: 1913578:LPB140_RS10140
uniprot id: A0A1L3JFA6
names: Subcellular Location Annotation
messages: Membrane

1913578:LPB140 RS03780
gene id: 1913578:LPB140_RS03780
uniprot id: A0A1L3JAH6
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1913578:LPB140 RS04060
gene id: 1913578:LPB140_RS04060
uniprot id: A0A1L3JAG0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

1913578:LPB140 RS00840
gene id: 1913578:LPB140_RS00840
uniprot id: A0A1L3JE90
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the QueC family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).

1913578:LPB140 RS01685
gene id: 1913578:LPB140_RS01685
uniprot id: A0A1L3J9I7
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the shikimate dehydrogenase family.
messages: Homodimer.
messages: Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1913578:LPB140 RS06145
gene id: 1913578:LPB140_RS06145
uniprot id: A0A1L3JBB8
names: Similarity
messages: Belongs to the peptidase M16 family.

1913578:LPB140 RS00790
gene id: 1913578:LPB140_RS00790
uniprot id: A0A1L3J917
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

1913578:LPB140 RS11905
gene id: 1913578:LPB140_RS11905
uniprot id: A0A1L3JE77
names: Similarity
messages: Belongs to the pyruvate kinase family.

1913578:LPB140 RS10885
gene id: 1913578:LPB140_RS10885
uniprot id: A0A1L3JDI1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PPase family.
messages: Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
messages: Cytoplasm
messages: Homohexamer.

1913578:LPB140 RS11030
gene id: 1913578:LPB140_RS11030
uniprot id: A0A1L3JDJ8
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

1913578:LPB140 RS06200
gene id: 1913578:LPB140_RS06200
uniprot id: A0A1L3JEU0
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

1913578:LPB140 RS11025
gene id: 1913578:LPB140_RS11025
uniprot id: A0A1L3JDJ5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.

1913578:LPB140 RS05810
gene id: 1913578:LPB140_RS05810
uniprot id: A0A1L3JB91
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurJ/MviN family.
messages: Cell inner membrane
messages: Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.
messages: Membrane

1913578:LPB140 RS09195
gene id: 1913578:LPB140_RS09195
uniprot id: A0A1L3JFA9
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

1913578:LPB140 RS11430
gene id: 1913578:LPB140_RS11430
uniprot id: A0A1L3JE03
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1913578:LPB140 RS08670
gene id: 1913578:LPB140_RS08670
uniprot id: A0A1L3JCJ3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1913578:LPB140 RS01935
gene id: 1913578:LPB140_RS01935
uniprot id: A0A1L3J9K0
names: Function
names: Similarity
messages: Belongs to the ribF family.
messages: Catalyzes the phosphorylation of riboflavin to FMN followed by the adenylation of FMN to FAD.

1913578:LPB140 RS09170
gene id: 1913578:LPB140_RS09170
uniprot id: A0A1L3JCY0
names: Function
names: Similarity
messages: Belongs to the CcmH/CycL/Ccl2/NrfF family.
messages: Possible subunit of a heme lyase.

1913578:LPB140 RS04095
gene id: 1913578:LPB140_RS04095
uniprot id: A0A1L3JAF8
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1913578:LPB140 RS05220
gene id: 1913578:LPB140_RS05220
uniprot id: A0A1L3JAZ7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

1913578:LPB140 RS04775
gene id: 1913578:LPB140_RS04775
uniprot id: A0A1L3JAR3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome b family.
messages: Binds 2 heme groups non-covalently.
messages: Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.
messages: Membrane
messages: The main subunits of complex b-c1 are: cytochrome b, cytochrome c1 and the Rieske protein.

1913578:LPB140 RS08530
gene id: 1913578:LPB140_RS08530
uniprot id: A0A1L3JCJ6
names: Subcellular Location Annotation
messages: Membrane

1913578:LPB140 RS09470
gene id: 1913578:LPB140_RS09470
uniprot id: A0A1L3JCX9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1913578:LPB140 RS11345
gene id: 1913578:LPB140_RS11345
uniprot id: A0A1L3JFA2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the pyridoxamine 5'-phosphate oxidase family.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
messages: Homodimer.

1913578:LPB140 RS09850
gene id: 1913578:LPB140_RS09850
uniprot id: A0A1L3JD35
names: Subcellular Location Annotation
messages: Membrane

1913578:LPB140 RS09365
gene id: 1913578:LPB140_RS09365
uniprot id: A0A1L3JCU7
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

1913578:LPB140 RS01890
gene id: 1913578:LPB140_RS01890
uniprot id: A0A1L3J9H4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the COX15/CtaA family. Type 2 subfamily.
messages: Catalyzes the conversion of heme O to heme A by two successive hydroxylations of the methyl group at C8. The first hydroxylation forms heme I, the second hydroxylation results in an unstable dihydroxymethyl group, which spontaneously dehydrates, resulting in the formyl group of heme A.
messages: Cell membrane
messages: Interacts with CtaB.
messages: Membrane

1913578:LPB140 RS07145
gene id: 1913578:LPB140_RS07145
uniprot id: A0A1L3JBR7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 20 kDa subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1913578:LPB140 RS06140
gene id: 1913578:LPB140_RS06140
uniprot id: A0A1L3JBJ5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PurS family.
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

1913578:LPB140 RS03845
gene id: 1913578:LPB140_RS03845
uniprot id: A0A1L3JAD0
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1913578:LPB140 RS06320
gene id: 1913578:LPB140_RS06320
uniprot id: A0A1L3JBF0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

1913578:LPB140 RS05340
gene id: 1913578:LPB140_RS05340
uniprot id: A0A1L3JB33
names: Subcellular Location Annotation
messages: Membrane

1913578:LPB140 RS04090
gene id: 1913578:LPB140_RS04090
uniprot id: A0A1L3JAH4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferrochelatase family.
messages: Catalyzes the ferrous insertion into protoporphyrin IX.
messages: Cytoplasm

1913578:LPB140 RS11330
gene id: 1913578:LPB140_RS11330
uniprot id: A0A1L3JDP1
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.

1913578:LPB140 RS05515
gene id: 1913578:LPB140_RS05515
uniprot id: A0A1L3JB31
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1913578:LPB140 RS11090
gene id: 1913578:LPB140_RS11090
uniprot id: A0A1L3JDL3
names: Similarity
messages: Belongs to the UDPGP type 2 family.

1913578:LPB140 RS09440
gene id: 1913578:LPB140_RS09440
uniprot id: A0A1L3JCT2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.
messages: Cell membrane
messages: Self-interacts. Interacts with FtsZ.

1913578:LPB140 RS09250
gene id: 1913578:LPB140_RS09250
uniprot id: A0A1L3JCT3
names: Caution
names: Function
names: Similarity
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1913578:LPB140 RS08380
gene id: 1913578:LPB140_RS08380
uniprot id: A0A1L3JCD7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

1913578:LPB140 RS05815
gene id: 1913578:LPB140_RS05815
uniprot id: A0A1L3JB69
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecB family.
messages: Cytoplasm
messages: Homotetramer, a dimer of dimers. One homotetramer interacts with 1 SecA dimer.
messages: One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA.

1913578:LPB140 RS09480
gene id: 1913578:LPB140_RS09480
uniprot id: A0A1L3JD31
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

1913578:LPB140 RS01770
gene id: 1913578:LPB140_RS01770
uniprot id: A0A1L3J9G9
names: Similarity
messages: Belongs to the peptidase U62 family.

1913578:LPB140 RS04165
gene id: 1913578:LPB140_RS04165
uniprot id: A0A1L3JAG7
names: Similarity
messages: Belongs to the GST superfamily. NadH family.

1913578:LPB140 RS06090
gene id: 1913578:LPB140_RS06090
uniprot id: A0A1L3JBE9
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity.

1913578:LPB140 RS08370
gene id: 1913578:LPB140_RS08370
uniprot id: A0A1L3JCE5
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

1913578:LPB140 RS03640
gene id: 1913578:LPB140_RS03640
uniprot id: A0A1L3JAA3
names: Similarity
messages: Belongs to the glycosyl hydrolase 5 (cellulase A) family.

1913578:LPB140 RS09600
gene id: 1913578:LPB140_RS09600
uniprot id: A0A1L3JCZ9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase H family.
messages: Binds 1 Mg(2+) ion per subunit. May bind a second metal ion at a regulatory site, or after substrate binding.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Monomer.

1913578:LPB140 RS07845
gene id: 1913578:LPB140_RS07845
uniprot id: A0A1L3JC51
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

1913578:LPB140 RS11270
gene id: 1913578:LPB140_RS11270
uniprot id: A0A1L3JDM9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the GTP cyclohydrolase II family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.

1913578:LPB140 RS08010
gene id: 1913578:LPB140_RS08010
uniprot id: A0A1L3JCE6
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta chain.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.

1913578:LPB140 RS03575
gene id: 1913578:LPB140_RS03575
uniprot id: A0A1L3JA84
names: Similarity
messages: Belongs to the KHG/KDPG aldolase family.

1913578:LPB140 RS09905
gene id: 1913578:LPB140_RS09905
uniprot id: A0A1L3JD45
names: Similarity
messages: Belongs to the peptidase M16 family.

1913578:LPB140 RS09650
gene id: 1913578:LPB140_RS09650
uniprot id: A0A1L3JD05
names: Subcellular Location Annotation
messages: Membrane

1913578:LPB140 RS02280
gene id: 1913578:LPB140_RS02280
uniprot id: A0A1L3J9N5
names: Similarity
messages: Belongs to the phosphohexose mutase family.

1913578:LPB140 RS04650
gene id: 1913578:LPB140_RS04650
uniprot id: A0A1L3JAQ7
names: Function
messages: This protein is a positive regulator for the phosphate regulon. Transcription of this operon is positively regulated by PhoB and PhoR when phosphate is limited.

1913578:LPB140 RS10085
gene id: 1913578:LPB140_RS10085
uniprot id: A0A1L3JD65
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Membrane
messages: Membrane-anchoring subunit of succinate dehydrogenase (SDH).
messages: Part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur protein, plus two membrane-anchoring proteins, SdhC and SdhD.

1913578:LPB140 RS11665
gene id: 1913578:LPB140_RS11665
uniprot id: A0A1L3JDW7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

1913578:LPB140 RS10165
gene id: 1913578:LPB140_RS10165
uniprot id: A0A1L3JDB1
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

1913578:LPB140 RS01590
gene id: 1913578:LPB140_RS01590
uniprot id: A0A1L3J9D5
names: Similarity
messages: Belongs to the UPF0174 family.

1913578:LPB140 RS12100
gene id: 1913578:LPB140_RS12100
uniprot id: A0A1L3JFE5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

1913578:LPB140 RS07830
gene id: 1913578:LPB140_RS07830
uniprot id: A0A1L3JC58
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1913578:LPB140 RS11875
gene id: 1913578:LPB140_RS11875
uniprot id: A0A1L3JDY6
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvA family.
messages: Cytoplasm
messages: Has three domains with a flexible linker between the domains II and III and assumes an 'L' shape. Domain III is highly mobile and contacts RuvB.
messages: Homotetramer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

1913578:LPB140 RS01900
gene id: 1913578:LPB140_RS01900
uniprot id: A0A1L3J9J0
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.

1913578:LPB140 RS05280
gene id: 1913578:LPB140_RS05280
uniprot id: A0A1L3JAZ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SUA5 family.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.

1913578:LPB140 RS00430
gene id: 1913578:LPB140_RS00430
uniprot id: A0A1L3JE96
names: Similarity
messages: Belongs to the KHG/KDPG aldolase family.

1913578:LPB140 RS03925
gene id: 1913578:LPB140_RS03925
uniprot id: A0A1L3JAK1
names: Similarity
messages: Belongs to the peptidase M16 family.

1913578:LPB140 RS09160
gene id: 1913578:LPB140_RS09160
uniprot id: A0A1L3JCQ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HAK/KUP transporter (TC 2.A.72) family.
messages: Cell membrane
messages: Membrane
messages: Transport of potassium into the cell. Likely operates as a K(+):H(+) symporter.

1913578:LPB140 RS10280
gene id: 1913578:LPB140_RS10280
uniprot id: A0A1L3JDD2
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

1913578:LPB140 RS06170
gene id: 1913578:LPB140_RS06170
uniprot id: A0A1L3JBE1
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with bS18 to 16S ribosomal RNA.

1913578:LPB140 RS05935
gene id: 1913578:LPB140_RS05935
uniprot id: A0A1L3JEU3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2).
messages: Homodimer.

1913578:LPB140 RS00705
gene id: 1913578:LPB140_RS00705
uniprot id: A0A1L3J907
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1913578:LPB140 RS04995
gene id: 1913578:LPB140_RS04995
uniprot id: A0A1L3JAW3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm

1913578:LPB140 RS11285
gene id: 1913578:LPB140_RS11285
uniprot id: A0A1L3JDT3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsK/SpoIIIE/SftA family.
messages: Essential cell division protein that coordinates cell division and chromosome segregation. The N-terminus is involved in assembly of the cell-division machinery. The C-terminus functions as a DNA motor that moves dsDNA in an ATP-dependent manner towards the dif recombination site, which is located within the replication terminus region. Translocation stops specifically at Xer-dif sites, where FtsK interacts with the Xer recombinase, allowing activation of chromosome unlinking by recombination. FtsK orienting polar sequences (KOPS) guide the direction of DNA translocation. FtsK can remove proteins from DNA as it translocates, but translocation stops specifically at XerCD-dif site, thereby preventing removal of XerC and XerD from dif.
messages: Homohexamer. Forms a ring that surrounds DNA.
messages: Membrane

1913578:LPB140 RS09235
gene id: 1913578:LPB140_RS09235
uniprot id: A0A1L3JCT9
names: Similarity
messages: Belongs to the Skp family.

1913578:LPB140 RS02920
gene id: 1913578:LPB140_RS02920
uniprot id: A0A1L3JA07
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Binds 1 [3Fe-4S] cluster.
messages: Binds 1 [4Fe-4S] cluster.
messages: Part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur, cytochrome b-556, and a hydrophobic anchor protein.

1913578:LPB140 RS07980
gene id: 1913578:LPB140_RS07980
uniprot id: A0A1L3JCA3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmG family. TrmFO subfamily.
messages: Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs.
messages: Cytoplasm

1913578:LPB140 RS00515
gene id: 1913578:LPB140_RS00515
uniprot id: A0A1L3J8X4
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

1913578:LPB140 RS07300
gene id: 1913578:LPB140_RS07300
uniprot id: A0A1L3JBW1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PpiC/parvulin rotamase family.
messages: Cell outer membrane
messages: Membrane

1913578:LPB140 RS09955
gene id: 1913578:LPB140_RS09955
uniprot id: A0A1L3JD83
names: Similarity
messages: Belongs to the UPF0053 family. Hemolysin C subfamily.

1913578:LPB140 RS06600
gene id: 1913578:LPB140_RS06600
uniprot id: A0A1L3JBI7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

1913578:LPB140 RS08415
gene id: 1913578:LPB140_RS08415
uniprot id: A0A1L3JCE2
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

1913578:LPB140 RS00520
gene id: 1913578:LPB140_RS00520
uniprot id: A0A1L3J8W0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MoaC family.
messages: Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
messages: Homohexamer; trimer of dimers.

1913578:LPB140 RS11245
gene id: 1913578:LPB140_RS11245
uniprot id: A0A1L3JF99
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

1913578:LPB140 RS11710
gene id: 1913578:LPB140_RS11710
uniprot id: A0A1L3JDW1
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: Methylated by PrmB.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

1913578:LPB140 RS00335
gene id: 1913578:LPB140_RS00335
uniprot id: A0A1L3J8T3
names: Similarity
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
messages: Belongs to the peroxiredoxin family. Prx6 subfamily.

1913578:LPB140 RS01710
gene id: 1913578:LPB140_RS01710
uniprot id: A0A1L3J9F2
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1913578:LPB140 RS04790
gene id: 1913578:LPB140_RS04790
uniprot id: A0A1L3JEN1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1913578:LPB140 RS11695
gene id: 1913578:LPB140_RS11695
uniprot id: A0A1L3JDW0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

1913578:LPB140 RS05015
gene id: 1913578:LPB140_RS05015
uniprot id: A0A1L3JAV0
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1913578:LPB140 RS07815
gene id: 1913578:LPB140_RS07815
uniprot id: A0A1L3JC42
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

1913578:LPB140 RS08085
gene id: 1913578:LPB140_RS08085
uniprot id: A0A1L3JC73
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoD/SigA subfamily.
messages: Cytoplasm
messages: Interacts transiently with the RNA polymerase catalytic core.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.

1913578:LPB140 RS04040
gene id: 1913578:LPB140_RS04040
uniprot id: A0A1L3JEK3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm

1913578:LPB140 RS01675
gene id: 1913578:LPB140_RS01675
uniprot id: A0A1L3J9G7
names: Function
names: Subunit
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease.

1913578:LPB140 RS09185
gene id: 1913578:LPB140_RS09185
uniprot id: A0A1L3JF36
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmE/CycJ family.
messages: Cell membrane
messages: Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH.

1913578:LPB140 RS07865
gene id: 1913578:LPB140_RS07865
uniprot id: A0A1L3JC49
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

1913578:LPB140 RS12485
gene id: 1913578:LPB140_RS12485
uniprot id: A0A1L3JE53
names: Similarity
messages: Belongs to the SDHAF4 family.

1913578:LPB140 RS00540
gene id: 1913578:LPB140_RS00540
uniprot id: A0A1L3JE66
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. MoaA family.
messages: Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.
messages: Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
messages: Monomer and homodimer.

1913578:LPB140 RS01995
gene id: 1913578:LPB140_RS01995
uniprot id: A0A1L3J9K9
names: Similarity
messages: Belongs to the ETF beta-subunit/FixA family.

1913578:LPB140 RS01875
gene id: 1913578:LPB140_RS01875
uniprot id: A0A1L3J9L4
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

1913578:LPB140 RS09075
gene id: 1913578:LPB140_RS09075
uniprot id: A0A1L3JCQ1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

1913578:LPB140 RS05475
gene id: 1913578:LPB140_RS05475
uniprot id: A0A1L3JB45
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

1913578:LPB140 RS02375
gene id: 1913578:LPB140_RS02375
uniprot id: A0A1L3J9R5
names: Similarity
messages: Belongs to the bacterial solute-binding protein 5 family.

1913578:LPB140 RS03175
gene id: 1913578:LPB140_RS03175
uniprot id: A0A1L3JA31
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP M family.
messages: Cell inner membrane
messages: Membrane

1913578:LPB140 RS01560
gene id: 1913578:LPB140_RS01560
uniprot id: A0A1L3J9G8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm

1913578:LPB140 RS08750
gene id: 1913578:LPB140_RS08750
uniprot id: A0A1L3JCK2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

1913578:LPB140 RS00855
gene id: 1913578:LPB140_RS00855
uniprot id: A0A1L3J927
names: Similarity
messages: Belongs to the peptidase U62 family.

1913578:LPB140 RS05835
gene id: 1913578:LPB140_RS05835
uniprot id: A0A1L3JBA4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M20A family. DapE subfamily.
messages: Binds 2 Zn(2+) or Co(2+) ions per subunit.
messages: Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls.
messages: Homodimer.

1913578:LPB140 RS06365
gene id: 1913578:LPB140_RS06365
uniprot id: A0A1L3JEV9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase PH family.
messages: Homohexameric ring arranged as a trimer of dimers.
messages: Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.

1913578:LPB140 RS04620
gene id: 1913578:LPB140_RS04620
uniprot id: A0A1L3JAP8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1913578:LPB140 RS07035
gene id: 1913578:LPB140_RS07035
uniprot id: A0A1L3JBS1
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

1913578:LPB140 RS02195
gene id: 1913578:LPB140_RS02195
uniprot id: A0A1L3JEC2
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1913578:LPB140 RS10420
gene id: 1913578:LPB140_RS10420
uniprot id: A0A1L3JDC0
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1913578:LPB140 RS11990
gene id: 1913578:LPB140_RS11990
uniprot id: A0A1L3JFD4
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

1913578:LPB140 RS12580
gene id: 1913578:LPB140_RS12580
uniprot id: A0A1L3JA72
names: Subcellular Location Annotation
messages: Cytoplasm

1913578:LPB140 RS01405
gene id: 1913578:LPB140_RS01405
uniprot id: A0A1L3J9B9
names: Similarity
messages: Belongs to the MreC family.

1913578:LPB140 RS04170
gene id: 1913578:LPB140_RS04170
uniprot id: A0A1L3JAI0
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1913578:LPB140 RS07330
gene id: 1913578:LPB140_RS07330
uniprot id: A0A1L3JBX3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

1913578:LPB140 RS06655
gene id: 1913578:LPB140_RS06655
uniprot id: A0A1L3JEU9
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

1913578:LPB140 RS08140
gene id: 1913578:LPB140_RS08140
uniprot id: A0A1L3JCA0
names: Function
names: Similarity
messages: Belongs to the helicase family. RecG subfamily.
messages: Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA).

1913578:LPB140 RS11895
gene id: 1913578:LPB140_RS11895
uniprot id: A0A1L3JFF6
names: Similarity
messages: Belongs to the UPF0145 family.

1913578:LPB140 RS09825
gene id: 1913578:LPB140_RS09825
uniprot id: A0A1L3JD64
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has four main subunits: a(1), b(1), b'(1) and c(9-12).
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

1913578:LPB140 RS01725
gene id: 1913578:LPB140_RS01725
uniprot id: A0A1L3JE98
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
messages: Binds 1 potassium ion per subunit.
messages: Cytoplasm
messages: Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1913578:LPB140 RS07475
gene id: 1913578:LPB140_RS07475
uniprot id: A0A1L3JF14
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Membrane