1897729:BOX17 RS07090
gene id: 1897729:BOX17_RS07090
uniprot id: A0A1J0VFC1
names: Function
names: Similarity
names: Subunit
messages: Catalyzes the ATP-dependent polymerization of arginine and aspartate to multi-L-arginyl-poly-L-aspartic acid (cyanophycin; a water-insoluble reserve polymer).
messages: Homodimer.
messages: In the C-terminal section; belongs to the MurCDEF family.

1897729:BOX17 RS09815
gene id: 1897729:BOX17_RS09815
uniprot id: A0A1J0VKL8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OmpP1/FadL family.
messages: Cell outer membrane
messages: Membrane

1897729:BOX17 RS15885
gene id: 1897729:BOX17_RS15885
uniprot id: A0A1J0VKS3
names: Subcellular Location Annotation
messages: Membrane

1897729:BOX17 RS16335
gene id: 1897729:BOX17_RS16335
uniprot id: A0A1J0VK09
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1897729:BOX17 RS12925
gene id: 1897729:BOX17_RS12925
uniprot id: A0A1J0VI95
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

1897729:BOX17 RS09195
gene id: 1897729:BOX17_RS09195
uniprot id: A0A1J0VGD2
names: Subcellular Location Annotation
messages: Membrane

1897729:BOX17 RS07760
gene id: 1897729:BOX17_RS07760
uniprot id: A0A1J0VFN0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1897729:BOX17 RS09910
gene id: 1897729:BOX17_RS09910
uniprot id: A0A1J0VGT4
names: Similarity
messages: Belongs to the UPF0758 family.

1897729:BOX17 RS15290
gene id: 1897729:BOX17_RS15290
uniprot id: A0A1J0VJG3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Membrane

1897729:BOX17 RS14545
gene id: 1897729:BOX17_RS14545
uniprot id: A0A1J0VJ42
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1897729:BOX17 RS15530
gene id: 1897729:BOX17_RS15530
uniprot id: A0A1J0VJL7
names: Similarity
messages: Belongs to the histone deacetylase family.

1897729:BOX17 RS07210
gene id: 1897729:BOX17_RS07210
uniprot id: A0A1J0VFI2
names: Caution
names: Function
names: Similarity
messages: Belongs to the globin family.
messages: In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
messages: Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1897729:BOX17 RS12210
gene id: 1897729:BOX17_RS12210
uniprot id: A0A1J0VHY3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family.
messages: Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system.
messages: The complex is composed of two ATP-binding proteins (PotA), two transmembrane proteins (PotB and PotC) and a solute-binding protein (PotD).

1897729:BOX17 RS11690
gene id: 1897729:BOX17_RS11690
uniprot id: A0A1J0VHP1
names: Subcellular Location Annotation
messages: Membrane

1897729:BOX17 RS05420
gene id: 1897729:BOX17_RS05420
uniprot id: A0A1J0VEM1
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity.

1897729:BOX17 RS10035
gene id: 1897729:BOX17_RS10035
uniprot id: A0A1J0VGT0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

1897729:BOX17 RS13855
gene id: 1897729:BOX17_RS13855
uniprot id: A0A1J0VIQ3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily.
messages: Catalyzes the transfer of the alpha-amino group from S-adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only aminotransferase known to utilize SAM as an amino donor.
messages: Cytoplasm
messages: Homodimer.

1897729:BOX17 RS10280
gene id: 1897729:BOX17_RS10280
uniprot id: A0A1J0VGZ4
names: Similarity
messages: Belongs to the glutamate synthase family.

1897729:BOX17 RS15680
gene id: 1897729:BOX17_RS15680
uniprot id: A0A1J0VJQ0
names: Function
names: Similarity
messages: Belongs to the ectoine synthase family.
messages: Catalyzes the circularization of gamma-N-acetyl-alpha,gamma-diaminobutyric acid (ADABA) to ectoine (1,4,5,6-tetrahydro-2-methyl-4-pyrimidine carboxylic acid), which is an excellent osmoprotectant.

1897729:BOX17 RS02195
gene id: 1897729:BOX17_RS02195
uniprot id: A0A1J0VD03
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

1897729:BOX17 RS06275
gene id: 1897729:BOX17_RS06275
uniprot id: A0A1J0VF18
names: Cofactor
names: Function
names: Similarity
messages: Adenine glycosylase active on G-A mispairs. MutY also corrects error-prone DNA synthesis past GO lesions which are due to the oxidatively damaged form of guanine: 7,8-dihydro-8-oxoguanine (8-oxo-dGTP).
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.

1897729:BOX17 RS01275
gene id: 1897729:BOX17_RS01275
uniprot id: A0A1J0VCE7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

1897729:BOX17 RS05445
gene id: 1897729:BOX17_RS05445
uniprot id: A0A1J0VEK2
names: Similarity
messages: Belongs to the YfgM family.

1897729:BOX17 RS00260
gene id: 1897729:BOX17_RS00260
uniprot id: A0A1J0VBZ0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1897729:BOX17 RS14705
gene id: 1897729:BOX17_RS14705
uniprot id: A0A1J0VJ72
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MoaC family.
messages: Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
messages: Homohexamer; trimer of dimers.

1897729:BOX17 RS15715
gene id: 1897729:BOX17_RS15715
uniprot id: A0A1J0VJQ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1897729:BOX17 RS10695
gene id: 1897729:BOX17_RS10695
uniprot id: A0A1J0VH66
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

1897729:BOX17 RS02725
gene id: 1897729:BOX17_RS02725
uniprot id: A0A1J0VD54
names: Function
messages: E1 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the decarboxylation of 2-oxoglutarate, the first step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).

1897729:BOX17 RS13320
gene id: 1897729:BOX17_RS13320
uniprot id: A0A1J0VIG3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

1897729:BOX17 RS07870
gene id: 1897729:BOX17_RS07870
uniprot id: A0A1J0VFQ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase delta chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

1897729:BOX17 RS13920
gene id: 1897729:BOX17_RS13920
uniprot id: A0A1J0VIR0
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

1897729:BOX17 RS07845
gene id: 1897729:BOX17_RS07845
uniprot id: A0A1J0VFP7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

1897729:BOX17 RS04795
gene id: 1897729:BOX17_RS04795
uniprot id: A0A1J0VE63
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family. T3SS ATPase subfamily.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has four main subunits: a(1), b(1), b'(1) and c(9-12).
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

1897729:BOX17 RS15140
gene id: 1897729:BOX17_RS15140
uniprot id: A0A1J0VJE4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

1897729:BOX17 RS00820
gene id: 1897729:BOX17_RS00820
uniprot id: A0A1J0VC68
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1897729:BOX17 RS06070
gene id: 1897729:BOX17_RS06070
uniprot id: A0A1J0VEU3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial diacylglycerol kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of sn-l,2-diacylglycerol (DAG) to phosphatidic acid. Involved in the recycling of diacylglycerol produced as a by-product during membrane-derived oligosaccharide (MDO) biosynthesis.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Mn(2+), Zn(2+), Cd(2+) and Co(2+) support activity to lesser extents.

1897729:BOX17 RS10530
gene id: 1897729:BOX17_RS10530
uniprot id: A0A1J0VH44
names: Similarity
messages: Belongs to the UPF0111 family.

1897729:BOX17 RS14130
gene id: 1897729:BOX17_RS14130
uniprot id: A0A1J0VIW9
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

1897729:BOX17 RS05610
gene id: 1897729:BOX17_RS05610
uniprot id: A0A1J0VEM8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M17 family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm
messages: Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.

1897729:BOX17 RS04225
gene id: 1897729:BOX17_RS04225
uniprot id: A0A1J0VDV1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the porin LamB (TC 1.B.3) family.
messages: Membrane

1897729:BOX17 RS01635
gene id: 1897729:BOX17_RS01635
uniprot id: A0A1J0VCL2
names: Similarity
messages: Belongs to the UPF0434 family.

1897729:BOX17 RS12840
gene id: 1897729:BOX17_RS12840
uniprot id: A0A1J0VI77
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1897729:BOX17 RS14005
gene id: 1897729:BOX17_RS14005
uniprot id: A0A1J0VIU6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

1897729:BOX17 RS09970
gene id: 1897729:BOX17_RS09970
uniprot id: A0A1J0VGT2
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

1897729:BOX17 RS07180
gene id: 1897729:BOX17_RS07180
uniprot id: A0A1J0VFG1
names: Similarity
names: Subunit
messages: Belongs to the Ahb/Nir family.
messages: Probably forms a complex composed of NirD, NirL, NirG and NirH. All proteins are required for the total conversion of siroheme to didecarboxysiroheme.

1897729:BOX17 RS13030
gene id: 1897729:BOX17_RS13030
uniprot id: A0A1J0VIE2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. PdxB subfamily.
messages: Catalyzes the oxidation of erythronate-4-phosphate to 3-hydroxy-2-oxo-4-phosphonooxybutanoate.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1897729:BOX17 RS14220
gene id: 1897729:BOX17_RS14220
uniprot id: A0A1J0VIY4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 1 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

1897729:BOX17 RS01770
gene id: 1897729:BOX17_RS01770
uniprot id: A0A1J0VCS7
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1897729:BOX17 RS12905
gene id: 1897729:BOX17_RS12905
uniprot id: A0A1J0VKN4
names: Function
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
messages: Catalyzes two reactions in de novo purine nucleotide biosynthesis. Catalyzes the breakdown of 5-aminoimidazole- (N-succinylocarboxamide) ribotide (SAICAR or 2-[5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamido]succinate) to 5-aminoimidazole-4-carboxamide ribotide (AICAR or 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide) and fumarate, and of adenylosuccinate (ADS or N(6)-(1,2-dicarboxyethyl)-AMP) to adenosine monophosphate (AMP) and fumarate.

1897729:BOX17 RS01700
gene id: 1897729:BOX17_RS01700
uniprot id: A0A1J0VCM3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

1897729:BOX17 RS13975
gene id: 1897729:BOX17_RS13975
uniprot id: A0A1J0VIR7
names: Function
names: Similarity
messages: Belongs to the MurCDEF family. Mpl subfamily.
messages: Reutilizes the intact tripeptide L-alanyl-gamma-D-glutamyl-meso-diaminopimelate by linking it to UDP-N-acetylmuramate.

1897729:BOX17 RS08610
gene id: 1897729:BOX17_RS08610
uniprot id: A0A1J0VG65
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

1897729:BOX17 RS15560
gene id: 1897729:BOX17_RS15560
uniprot id: A0A1J0VJM3
names: Similarity
messages: Belongs to the WrbA family.

1897729:BOX17 RS01845
gene id: 1897729:BOX17_RS01845
uniprot id: A0A1J0VCP1
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

1897729:BOX17 RS08715
gene id: 1897729:BOX17_RS08715
uniprot id: A0A1J0VG62
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

1897729:BOX17 RS01135
gene id: 1897729:BOX17_RS01135
uniprot id: A0A1J0VCB9
names: Similarity
messages: Belongs to the DNA polymerase type-B family.

1897729:BOX17 RS11315
gene id: 1897729:BOX17_RS11315
uniprot id: A0A1J0VHH6
names: Similarity
messages: Belongs to the UPF0229 family.

1897729:BOX17 RS10110
gene id: 1897729:BOX17_RS10110
uniprot id: A0A1J0VGW1
names: Similarity
messages: Belongs to the GppA/Ppx family.

1897729:BOX17 RS04845
gene id: 1897729:BOX17_RS04845
uniprot id: A0A1J0VE85
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arginine deiminase family.
messages: Cytoplasm

1897729:BOX17 RS12990
gene id: 1897729:BOX17_RS12990
uniprot id: A0A1J0VIE1
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. TrmA subfamily.
messages: Dual-specificity methyltransferase that catalyzes the formation of 5-methyluridine at position 54 (m5U54) in all tRNAs, and that of position 341 (m5U341) in tmRNA (transfer-mRNA).

1897729:BOX17 RS09110
gene id: 1897729:BOX17_RS09110
uniprot id: A0A1J0VGF1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

1897729:BOX17 RS03080
gene id: 1897729:BOX17_RS03080
uniprot id: A0A1J0VDB3
names: Subcellular Location Annotation
messages: Membrane

1897729:BOX17 RS14145
gene id: 1897729:BOX17_RS14145
uniprot id: A0A1J0VIV3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrC family.
messages: Cell membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

1897729:BOX17 RS10070
gene id: 1897729:BOX17_RS10070
uniprot id: A0A1J0VGV9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
messages: Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
messages: Homotrimer.

1897729:BOX17 RS03485
gene id: 1897729:BOX17_RS03485
uniprot id: A0A1J0VDI0
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1897729:BOX17 RS00635
gene id: 1897729:BOX17_RS00635
uniprot id: A0A1J0VC57
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1897729:BOX17 RS04670
gene id: 1897729:BOX17_RS04670
uniprot id: A0A1J0VE42
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the calycin superfamily. Lipocalin family.
messages: Cell outer membrane
messages: Homodimer.
messages: Involved in the storage or transport of lipids necessary for membrane maintenance under stressful conditions. Displays a binding preference for lysophospholipids.

1897729:BOX17 RS15615
gene id: 1897729:BOX17_RS15615
uniprot id: A0A1J0VJN4
names: Similarity
messages: Belongs to the SufE family.

1897729:BOX17 RS14935
gene id: 1897729:BOX17_RS14935
uniprot id: A0A1J0VKT0
names: Cofactor
messages: Binds 1 Mg(2+) ion per subunit.

1897729:BOX17 RS12640
gene id: 1897729:BOX17_RS12640
uniprot id: A0A1J0VI78
names: Subcellular Location Annotation
messages: Cytoplasm

1897729:BOX17 RS11905
gene id: 1897729:BOX17_RS11905
uniprot id: A0A1J0VHR7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1897729:BOX17 RS12910
gene id: 1897729:BOX17_RS12910
uniprot id: A0A1J0VIA0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HflD family.
messages: Cell membrane
messages: Cytoplasm

1897729:BOX17 RS13050
gene id: 1897729:BOX17_RS13050
uniprot id: A0A1J0VIB9
names: Cofactor
names: Similarity
messages: Belongs to the MsrB Met sulfoxide reductase family.
messages: Binds 1 zinc ion per subunit. The zinc ion is important for the structural integrity of the protein.

1897729:BOX17 RS16520
gene id: 1897729:BOX17_RS16520
uniprot id: A0A1J0VK38
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

1897729:BOX17 RS06470
gene id: 1897729:BOX17_RS06470
uniprot id: A0A1J0VF05
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.
messages: Cytoplasm
messages: May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.

1897729:BOX17 RS09220
gene id: 1897729:BOX17_RS09220
uniprot id: A0A1J0VGF5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thioester dehydratase family. FabA subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)-decenoyl-ACP. Can catalyze the dehydratase reaction for beta-hydroxyacyl-ACPs with saturated chain lengths up to 16:0, being most active on intermediate chain length.

1897729:BOX17 RS04340
gene id: 1897729:BOX17_RS04340
uniprot id: A0A1J0VDZ7
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.

1897729:BOX17 RS03835
gene id: 1897729:BOX17_RS03835
uniprot id: A0A1J0VDN3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SurE nucleotidase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Cytoplasm
messages: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.

1897729:BOX17 RS10220
gene id: 1897729:BOX17_RS10220
uniprot id: A0A1J0VGW3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.

1897729:BOX17 RS08045
gene id: 1897729:BOX17_RS08045
uniprot id: A0A1J0VFT3
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. HldD subfamily.
messages: Binds 1 NADP(+) per subunit.
messages: Catalyzes the interconversion between ADP-D-glycero-beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose.
messages: Contains a large N-terminal NADP-binding domain, and a smaller C-terminal substrate-binding domain.
messages: Homopentamer.

1897729:BOX17 RS14255
gene id: 1897729:BOX17_RS14255
uniprot id: A0A1J0VKQ7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

1897729:BOX17 RS15215
gene id: 1897729:BOX17_RS15215
uniprot id: A0A1J0VJF8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1897729:BOX17 RS01875
gene id: 1897729:BOX17_RS01875
uniprot id: A0A1J0VCR2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.

1897729:BOX17 RS00485
gene id: 1897729:BOX17_RS00485
uniprot id: A0A1J0VC14
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

1897729:BOX17 RS15350
gene id: 1897729:BOX17_RS15350
uniprot id: A0A1J0VJI4
names: Similarity
messages: Belongs to the transglycosylase Slt family.

1897729:BOX17 RS08455
gene id: 1897729:BOX17_RS08455
uniprot id: A0A1J0VG24
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

1897729:BOX17 RS01555
gene id: 1897729:BOX17_RS01555
uniprot id: A0A1J0VCK0
names: Subunit
messages: Homodimer.

1897729:BOX17 RS03040
gene id: 1897729:BOX17_RS03040
uniprot id: A0A1J0VDA5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PNT beta subunit family.
messages: Cell inner membrane
messages: Heterodimer of an alpha and a beta chain.
messages: Membrane
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

1897729:BOX17 RS12075
gene id: 1897729:BOX17_RS12075
uniprot id: A0A1J0VHV1
names: Function
names: Similarity
messages: Belongs to the DtxR/MntR family.
messages: In the presence of manganese, represses expression of mntH and mntS. Up-regulates expression of mntP.

1897729:BOX17 RS01780
gene id: 1897729:BOX17_RS01780
uniprot id: A0A1J0VCQ2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsL family.
messages: Cell inner membrane
messages: Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.
messages: Membrane
messages: Part of a complex composed of FtsB, FtsL and FtsQ.

1897729:BOX17 RS04185
gene id: 1897729:BOX17_RS04185
uniprot id: A0A1J0VDV4
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1897729:BOX17 RS07415
gene id: 1897729:BOX17_RS07415
uniprot id: A0A1J0VFH1
names: Similarity
messages: Belongs to the four-carbon acid sugar kinase family.

1897729:BOX17 RS07385
gene id: 1897729:BOX17_RS07385
uniprot id: A0A1J0VFG5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

1897729:BOX17 RS10080
gene id: 1897729:BOX17_RS10080
uniprot id: A0A1J0VGU7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxA subfamily.
messages: Cytoplasm
messages: Homotrimer.
messages: Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

1897729:BOX17 RS08220
gene id: 1897729:BOX17_RS08220
uniprot id: A0A1J0VFY3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

1897729:BOX17 RS11425
gene id: 1897729:BOX17_RS11425
uniprot id: A0A1J0VHH5
names: Subcellular Location Annotation
messages: Membrane

1897729:BOX17 RS11435
gene id: 1897729:BOX17_RS11435
uniprot id: A0A1J0VHH4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1897729:BOX17 RS08255
gene id: 1897729:BOX17_RS08255
uniprot id: A0A1J0VFY8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the GTP cyclohydrolase II family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.

1897729:BOX17 RS13110
gene id: 1897729:BOX17_RS13110
uniprot id: A0A1J0VID6
names: Cofactor
names: Similarity
messages: Belongs to the nitroreductase family.
messages: Binds 1 FMN per subunit.

1897729:BOX17 RS08430
gene id: 1897729:BOX17_RS08430
uniprot id: A0A1J0VFZ9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

1897729:BOX17 RS03610
gene id: 1897729:BOX17_RS03610
uniprot id: A0A1J0VDL2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DHBP synthase family.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Homodimer.
messages: In the C-terminal section; belongs to the GTP cyclohydrolase II family.
messages: In the N-terminal section; belongs to the DHBP synthase family.

1897729:BOX17 RS05010
gene id: 1897729:BOX17_RS05010
uniprot id: A0A1J0VE98
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit contributes ATPase, 3'-5' helicase, exonuclease activity and loads RecA onto ssDNA.
messages: Belongs to the helicase family. UvrD subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotrimer of RecB, RecC and RecD. All subunits contribute to DNA-binding. Interacts with RecA.
messages: The C-terminal domain has nuclease activity and interacts with RecD. It interacts with RecA, facilitating its loading onto ssDNA.
messages: The N-terminal DNA-binding domain is a ssDNA-dependent ATPase and has ATP-dependent 3'-5' helicase function. This domain interacts with RecC.

1897729:BOX17 RS05885
gene id: 1897729:BOX17_RS05885
uniprot id: A0A1J0VET0
names: Similarity
messages: Belongs to the intradiol ring-cleavage dioxygenase family.

1897729:BOX17 RS11380
gene id: 1897729:BOX17_RS11380
uniprot id: A0A1J0VHH2
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins.

1897729:BOX17 RS10345
gene id: 1897729:BOX17_RS10345
uniprot id: A0A1J0VGY8
names: Similarity
messages: Belongs to the aspartokinase family.

1897729:BOX17 RS10505
gene id: 1897729:BOX17_RS10505
uniprot id: A0A1J0VH39
names: Similarity
messages: Belongs to the YciI family.

1897729:BOX17 RS03465
gene id: 1897729:BOX17_RS03465
uniprot id: A0A1J0VDK0
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1897729:BOX17 RS14870
gene id: 1897729:BOX17_RS14870
uniprot id: A0A1J0VJ91
names: Subcellular Location Annotation
messages: Membrane

1897729:BOX17 RS01330
gene id: 1897729:BOX17_RS01330
uniprot id: A0A1J0VCG0
names: Cofactor
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.
messages: Probably binds two magnesium or manganese ions per subunit.

1897729:BOX17 RS00945
gene id: 1897729:BOX17_RS00945
uniprot id: A0A1J0VCC5
names: Similarity
messages: Belongs to the UPF0047 family.

1897729:BOX17 RS06410
gene id: 1897729:BOX17_RS06410
uniprot id: A0A1J0VF16
names: Subcellular Location Annotation
messages: Membrane

1897729:BOX17 RS12225
gene id: 1897729:BOX17_RS12225
uniprot id: A0A1J0VI00
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1897729:BOX17 RS02990
gene id: 1897729:BOX17_RS02990
uniprot id: A0A1J0VDD4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Reduced FMN (FMNH(2)).

1897729:BOX17 RS12690
gene id: 1897729:BOX17_RS12690
uniprot id: A0A1J0VI87
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome b560 family.
messages: Membrane
messages: Membrane-anchoring subunit of succinate dehydrogenase (SDH).
messages: Part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur protein, plus two membrane-anchoring proteins, SdhC and SdhD. The complex can form homotrimers.
messages: The heme is bound between the two transmembrane subunits.

1897729:BOX17 RS07835
gene id: 1897729:BOX17_RS07835
uniprot id: A0A1J0VFR2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ApbE family.
messages: Cell inner membrane
messages: Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein.
messages: Magnesium. Can also use manganese.

1897729:BOX17 RS02525
gene id: 1897729:BOX17_RS02525
uniprot id: A0A1J0VD21
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.

1897729:BOX17 RS01405
gene id: 1897729:BOX17_RS01405
uniprot id: A0A1J0VCH1
names: Similarity
messages: Belongs to the myoviridae tail sheath protein family.

1897729:BOX17 RS09040
gene id: 1897729:BOX17_RS09040
uniprot id: A0A1J0VGD4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

1897729:BOX17 RS16495
gene id: 1897729:BOX17_RS16495
uniprot id: A0A1J0VK37
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. ATZ/TRZ family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia.

1897729:BOX17 RS07075
gene id: 1897729:BOX17_RS07075
uniprot id: A0A1J0VFA9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Membrane

1897729:BOX17 RS02955
gene id: 1897729:BOX17_RS02955
uniprot id: A0A1J0VD82
names: Similarity
messages: Belongs to the PhoH family.

1897729:BOX17 RS09895
gene id: 1897729:BOX17_RS09895
uniprot id: A0A1J0VGT3
names: Similarity
messages: Belongs to the phosphohexose mutase family.

1897729:BOX17 RS03930
gene id: 1897729:BOX17_RS03930
uniprot id: A0A1J0VDR7
names: Similarity
messages: Belongs to the KHG/KDPG aldolase family.

1897729:BOX17 RS02155
gene id: 1897729:BOX17_RS02155
uniprot id: A0A1J0VCW2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1897729:BOX17 RS01600
gene id: 1897729:BOX17_RS01600
uniprot id: A0A1J0VCP5
names: Similarity
messages: Belongs to the peptidase S49 family.

1897729:BOX17 RS02000
gene id: 1897729:BOX17_RS02000
uniprot id: A0A1J0VCV4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YhdE subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

1897729:BOX17 RS12710
gene id: 1897729:BOX17_RS12710
uniprot id: A0A1J0VI69
names: Function
names: Similarity
messages: Belongs to the alpha-ketoglutarate dehydrogenase family.
messages: E1 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the decarboxylation of 2-oxoglutarate, the first step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).

1897729:BOX17 RS12100
gene id: 1897729:BOX17_RS12100
uniprot id: A0A1J0VHU6
names: Similarity
messages: Belongs to the Gfa family.

1897729:BOX17 RS10910
gene id: 1897729:BOX17_RS10910
uniprot id: A0A1J0VHA9
names: Similarity
messages: Belongs to the DNA polymerase type-Y family.

1897729:BOX17 RS07655
gene id: 1897729:BOX17_RS07655
uniprot id: A0A1J0VFM1
names: Similarity
messages: Belongs to the YicC/YloC family.

1897729:BOX17 RS10015
gene id: 1897729:BOX17_RS10015
uniprot id: A0A1J0VGT7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

1897729:BOX17 RS05485
gene id: 1897729:BOX17_RS05485
uniprot id: A0A1J0VEL2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the aerobic coproporphyrinogen-III oxidase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX.

1897729:BOX17 RS00570
gene id: 1897729:BOX17_RS00570
uniprot id: A0A1J0VC27
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.
messages: Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA.
messages: Cytoplasm
messages: Homodimer.

1897729:BOX17 RS01775
gene id: 1897729:BOX17_RS01775
uniprot id: A0A1J0VCP2
names: Function
names: Similarity
messages: Belongs to the transpeptidase family. FtsI subfamily.
messages: Catalyzes cross-linking of the peptidoglycan cell wall at the division septum.

1897729:BOX17 RS03085
gene id: 1897729:BOX17_RS03085
uniprot id: A0A1J0VDA7
names: Subcellular Location Annotation
messages: Cytoplasm

1897729:BOX17 RS09775
gene id: 1897729:BOX17_RS09775
uniprot id: A0A1J0VGQ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbC subfamily.
messages: Periplasm
messages: Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process.

1897729:BOX17 RS15310
gene id: 1897729:BOX17_RS15310
uniprot id: A0A1J0VJH6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EamA transporter family.
messages: Membrane

1897729:BOX17 RS07920
gene id: 1897729:BOX17_RS07920
uniprot id: A0A1J0VFV8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

1897729:BOX17 RS09395
gene id: 1897729:BOX17_RS09395
uniprot id: A0A1J0VGI8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

1897729:BOX17 RS07405
gene id: 1897729:BOX17_RS07405
uniprot id: A0A1J0VFH6
names: Similarity
messages: Belongs to the hyi family.

1897729:BOX17 RS04125
gene id: 1897729:BOX17_RS04125
uniprot id: A0A1J0VDT7
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1897729:BOX17 RS10490
gene id: 1897729:BOX17_RS10490
uniprot id: A0A1J0VH38
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1897729:BOX17 RS05560
gene id: 1897729:BOX17_RS05560
uniprot id: A0A1J0VKE0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AceK family.
messages: Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation.
messages: Cytoplasm

1897729:BOX17 RS05405
gene id: 1897729:BOX17_RS05405
uniprot id: A0A1J0VEJ4
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

1897729:BOX17 RS08590
gene id: 1897729:BOX17_RS08590
uniprot id: A0A1J0VG48
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamE family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

1897729:BOX17 RS09500
gene id: 1897729:BOX17_RS09500
uniprot id: A0A1J0VGK4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP H family.
messages: Cell inner membrane
messages: Membrane

1897729:BOX17 RS12010
gene id: 1897729:BOX17_RS12010
uniprot id: A0A1J0VHS2
names: Subcellular Location Annotation
messages: Membrane

1897729:BOX17 RS10120
gene id: 1897729:BOX17_RS10120
uniprot id: A0A1J0VGV2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UbiD family.
messages: Binds 1 prenylated FMN (prenyl-FMN) per subunit.
messages: Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis.
messages: Cell membrane
messages: Homohexamer.

1897729:BOX17 RS15255
gene id: 1897729:BOX17_RS15255
uniprot id: A0A1J0VJE0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

1897729:BOX17 RS01840
gene id: 1897729:BOX17_RS01840
uniprot id: A0A1J0VCS3
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Rieske iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.
messages: Membrane
messages: The Rieske protein is a high potential 2Fe-2S protein.
messages: The main subunits of complex b-c1 are: cytochrome b, cytochrome c1 and the Rieske protein.

1897729:BOX17 RS16420
gene id: 1897729:BOX17_RS16420
uniprot id: A0A1J0VK25
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the AP endonuclease 2 family.
messages: Binds 3 Zn(2+) ions.
messages: Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate.

1897729:BOX17 RS08555
gene id: 1897729:BOX17_RS08555
uniprot id: A0A1J0VG12
names: Similarity
messages: Belongs to the aspartokinase family.

1897729:BOX17 RS04245
gene id: 1897729:BOX17_RS04245
uniprot id: A0A1J0VDX9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1897729:BOX17 RS11925
gene id: 1897729:BOX17_RS11925
uniprot id: A0A1J0VHQ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1897729:BOX17 RS01105
gene id: 1897729:BOX17_RS01105
uniprot id: A0A1J0VCB0
names: Similarity
messages: Belongs to the carbamate kinase family.

1897729:BOX17 RS11195
gene id: 1897729:BOX17_RS11195
uniprot id: A0A1J0VHG1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1897729:BOX17 RS06290
gene id: 1897729:BOX17_RS06290
uniprot id: A0A1J0VF07
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

1897729:BOX17 RS10335
gene id: 1897729:BOX17_RS10335
uniprot id: A0A1J0VGZ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecX family.
messages: Cytoplasm
messages: Modulates RecA activity.

1897729:BOX17 RS06445
gene id: 1897729:BOX17_RS06445
uniprot id: A0A1J0VF09
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1897729:BOX17 RS02220
gene id: 1897729:BOX17_RS02220
uniprot id: A0A1J0VCZ8
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.

1897729:BOX17 RS15175
gene id: 1897729:BOX17_RS15175
uniprot id: A0A1J0VJF1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LpxH family.
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.
messages: Binds 2 Mn(2+) ions per subunit in a binuclear metal center.
messages: Cell inner membrane
messages: Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

1897729:BOX17 RS07345
gene id: 1897729:BOX17_RS07345
uniprot id: A0A1J0VFF8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

1897729:BOX17 RS03975
gene id: 1897729:BOX17_RS03975
uniprot id: A0A1J0VDS6
names: Subcellular Location Annotation
messages: Membrane

1897729:BOX17 RS11660
gene id: 1897729:BOX17_RS11660
uniprot id: A0A1J0VHL3
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.

1897729:BOX17 RS04535
gene id: 1897729:BOX17_RS04535
uniprot id: A0A1J0VE08
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

1897729:BOX17 RS08135
gene id: 1897729:BOX17_RS08135
uniprot id: A0A1J0VFU9
names: Similarity
messages: Belongs to the UbiH/COQ6 family.

1897729:BOX17 RS03420
gene id: 1897729:BOX17_RS03420
uniprot id: A0A1J0VDI3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

1897729:BOX17 RS02120
gene id: 1897729:BOX17_RS02120
uniprot id: A0A1J0VCW3
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.

1897729:BOX17 RS13485
gene id: 1897729:BOX17_RS13485
uniprot id: A0A1J0VIL2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

1897729:BOX17 RS00410
gene id: 1897729:BOX17_RS00410
uniprot id: A0A1J0VC40
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.

1897729:BOX17 RS03195
gene id: 1897729:BOX17_RS03195
uniprot id: A0A1J0VK84
names: Function
names: Similarity
messages: Belongs to the band 7/mec-2 family. HflC subfamily.
messages: HflC and HflK could regulate a protease.

1897729:BOX17 RS02325
gene id: 1897729:BOX17_RS02325
uniprot id: A0A1J0VCY9
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

1897729:BOX17 RS01640
gene id: 1897729:BOX17_RS01640
uniprot id: A0A1J0VCQ1
names: Caution
names: Function
names: Similarity
messages: Belongs to the LpxK family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).

1897729:BOX17 RS13990
gene id: 1897729:BOX17_RS13990
uniprot id: A0A1J0VIV4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Membrane

1897729:BOX17 RS05435
gene id: 1897729:BOX17_RS05435
uniprot id: A0A1J0VEJ5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

1897729:BOX17 RS15875
gene id: 1897729:BOX17_RS15875
uniprot id: A0A1J0VJS4
names: Similarity
messages: Belongs to the acylphosphatase family.

1897729:BOX17 RS06000
gene id: 1897729:BOX17_RS06000
uniprot id: A0A1J0VET7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1897729:BOX17 RS13765
gene id: 1897729:BOX17_RS13765
uniprot id: A0A1J0VIP2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

1897729:BOX17 RS13225
gene id: 1897729:BOX17_RS13225
uniprot id: A0A1J0VIE7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Membrane

1897729:BOX17 RS03845
gene id: 1897729:BOX17_RS03845
uniprot id: A0A1J0VKB6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IspF family.
messages: Binds 1 divalent metal cation per subunit.
messages: Homotrimer.
messages: Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).

1897729:BOX17 RS07940
gene id: 1897729:BOX17_RS07940
uniprot id: A0A1J0VFS3
names: Subcellular Location Annotation
messages: Membrane

1897729:BOX17 RS00115
gene id: 1897729:BOX17_RS00115
uniprot id: A0A1J0VK49
names: Cofactor
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.
messages: Binds 1 [4Fe-4S] cluster per subunit.

1897729:BOX17 RS09960
gene id: 1897729:BOX17_RS09960
uniprot id: A0A1J0VGU3
names: Function
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.
messages: Catalyzes the isomerization of citrate to isocitrate via cis-aconitate.

1897729:BOX17 RS02905
gene id: 1897729:BOX17_RS02905
uniprot id: A0A1J0VD76
names: Function
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family.
messages: Specifically catalyzes the dephosphorylation of 2-phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress.

1897729:BOX17 RS12230
gene id: 1897729:BOX17_RS12230
uniprot id: A0A1J0VI02
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Homohexamer.
messages: In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.
messages: In the N-terminal section; belongs to the CobB/CobQ family.
messages: Involved in acetate metabolism.
messages: The N-terminal region seems to be important for proper quaternary structure. The C-terminal region contains the substrate-binding site.

1897729:BOX17 RS00275
gene id: 1897729:BOX17_RS00275
uniprot id: A0A1J0VC18
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RdgC family.
messages: May be involved in recombination.
messages: nucleoid

1897729:BOX17 RS16175
gene id: 1897729:BOX17_RS16175
uniprot id: A0A1J0VJY9
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
messages: Carbon 2 of the heme B porphyrin ring is defined according to the Fischer nomenclature.
messages: Cell membrane
messages: Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
messages: Membrane

1897729:BOX17 RS01920
gene id: 1897729:BOX17_RS01920
uniprot id: A0A1J0VCT9
names: Subcellular Location Annotation
messages: Membrane

1897729:BOX17 RS07115
gene id: 1897729:BOX17_RS07115
uniprot id: A0A1J0VFG4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Membrane

1897729:BOX17 RS14460
gene id: 1897729:BOX17_RS14460
uniprot id: A0A1J0VJ26
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SIMIBI class G3E GTPase family. UreG subfamily.
messages: Cytoplasm
messages: Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG.
messages: Homodimer. UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

1897729:BOX17 RS16200
gene id: 1897729:BOX17_RS16200
uniprot id: A0A1J0VJZ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Membrane

1897729:BOX17 RS16515
gene id: 1897729:BOX17_RS16515
uniprot id: A0A1J0VK42
names: Subcellular Location Annotation
messages: Membrane

1897729:BOX17 RS07175
gene id: 1897729:BOX17_RS07175
uniprot id: A0A1J0VFC4
names: Similarity
names: Subunit
messages: Belongs to the Ahb/Nir family.
messages: Probably forms a complex composed of NirD, NirL, NirG and NirH. All proteins are required for the total conversion of siroheme to didecarboxysiroheme.

1897729:BOX17 RS08745
gene id: 1897729:BOX17_RS08745
uniprot id: A0A1J0VG52
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1897729:BOX17 RS08730
gene id: 1897729:BOX17_RS08730
uniprot id: A0A1J0VG67
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

1897729:BOX17 RS02535
gene id: 1897729:BOX17_RS02535
uniprot id: A0A1J0VD65
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

1897729:BOX17 RS07755
gene id: 1897729:BOX17_RS07755
uniprot id: A0A1J0VFS4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Membrane

1897729:BOX17 RS04640
gene id: 1897729:BOX17_RS04640
uniprot id: A0A1J0VE46
names: Similarity
messages: Belongs to the gamma-BBH/TMLD family.

1897729:BOX17 RS05655
gene id: 1897729:BOX17_RS05655
uniprot id: A0A1J0VEM6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Also exhibits azoreductase activity. Catalyzes the reductive cleavage of the azo bond in aromatic azo compounds to the corresponding amines.
messages: Belongs to the azoreductase type 1 family.
messages: Binds 1 FMN per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Quinone reductase that provides resistance to thiol-specific stress caused by electrophilic quinones.

1897729:BOX17 RS02205
gene id: 1897729:BOX17_RS02205
uniprot id: A0A1J0VCX7
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

1897729:BOX17 RS07915
gene id: 1897729:BOX17_RS07915
uniprot id: A0A1J0VFS9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Membrane

1897729:BOX17 RS06840
gene id: 1897729:BOX17_RS06840
uniprot id: A0A1J0VF80
names: Similarity
messages: Belongs to the peptidase C40 family.

1897729:BOX17 RS07880
gene id: 1897729:BOX17_RS07880
uniprot id: A0A1J0VFV0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Membrane

1897729:BOX17 RS15095
gene id: 1897729:BOX17_RS15095
uniprot id: A0A1J0VJD7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
messages: Homodimer.

1897729:BOX17 RS01620
gene id: 1897729:BOX17_RS01620
uniprot id: A0A1J0VCL5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

1897729:BOX17 RS00940
gene id: 1897729:BOX17_RS00940
uniprot id: A0A1J0VC87
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Membrane

1897729:BOX17 RS09875
gene id: 1897729:BOX17_RS09875
uniprot id: A0A1J0VGS2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
messages: Cell inner membrane
messages: Forms a membrane-associated complex with FtsE.
messages: Membrane
messages: Part of the ABC transporter FtsEX involved in cellular division.

1897729:BOX17 RS09640
gene id: 1897729:BOX17_RS09640
uniprot id: A0A1J0VGM6
names: Similarity
messages: Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily.

1897729:BOX17 RS13085
gene id: 1897729:BOX17_RS13085
uniprot id: A0A1J0VID7
names: Subcellular Location Annotation
messages: Membrane

1897729:BOX17 RS14980
gene id: 1897729:BOX17_RS14980
uniprot id: A0A1J0VJB9
names: Subcellular Location Annotation
messages: Membrane

1897729:BOX17 RS07340
gene id: 1897729:BOX17_RS07340
uniprot id: A0A1J0VFF7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.
messages: Serves to protect the cell against DNA damage by alkyl hydroperoxides. It can use either NADH or NADPH as electron donor for direct reduction of redox dyes or of alkyl hydroperoxides when combined with the AhpC protein.

1897729:BOX17 RS09085
gene id: 1897729:BOX17_RS09085
uniprot id: A0A1J0VGE1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

1897729:BOX17 RS03600
gene id: 1897729:BOX17_RS03600
uniprot id: A0A1J0VDM3
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

1897729:BOX17 RS00420
gene id: 1897729:BOX17_RS00420
uniprot id: A0A1J0VC13
names: Similarity
messages: Belongs to the glutaredoxin family. Monothiol subfamily.

1897729:BOX17 RS06720
gene id: 1897729:BOX17_RS06720
uniprot id: A0A1J0VF56
names: Subcellular Location Annotation
messages: Membrane

1897729:BOX17 RS13885
gene id: 1897729:BOX17_RS13885
uniprot id: A0A1J0VIS9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. Biotin synthase family.
messages: Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
messages: Homodimer.

1897729:BOX17 RS12025
gene id: 1897729:BOX17_RS12025
uniprot id: A0A1J0VHU3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1897729:BOX17 RS09015
gene id: 1897729:BOX17_RS09015
uniprot id: A0A1J0VGB4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

1897729:BOX17 RS03290
gene id: 1897729:BOX17_RS03290
uniprot id: A0A1J0VDK2
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

1897729:BOX17 RS07250
gene id: 1897729:BOX17_RS07250
uniprot id: A0A1J0VFJ1
names: Function
names: Similarity
messages: Belongs to the UbiT family.
messages: Required for O(2)-independent ubiquinone (coenzyme Q) biosynthesis. Likely functions as an accessory factor.

1897729:BOX17 RS07805
gene id: 1897729:BOX17_RS07805
uniprot id: A0A1J0VFN1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1897729:BOX17 RS11325
gene id: 1897729:BOX17_RS11325
uniprot id: A0A1J0VHG8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the high-potential iron-sulfur protein (HiPIP) family.
messages: Homodimer.
messages: Specific class of high-redox-potential 4Fe-4S ferredoxins. Functions in anaerobic electron transport in most purple and in some other photosynthetic bacteria and in at least one genus (Paracoccus) of halophilic, denitrifying bacteria.

1897729:BOX17 RS09025
gene id: 1897729:BOX17_RS09025
uniprot id: A0A1J0VGD6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1897729:BOX17 RS16030
gene id: 1897729:BOX17_RS16030
uniprot id: A0A1J0VJU9
names: Similarity
names: Subunit
messages: Belongs to the glutaredoxin family.
messages: Monomer.

1897729:BOX17 RS12940
gene id: 1897729:BOX17_RS12940
uniprot id: A0A1J0VID3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ClpS family.
messages: Binds to the N-terminal domain of the chaperone ClpA.
messages: Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation.

1897729:BOX17 RS11860
gene id: 1897729:BOX17_RS11860
uniprot id: A0A1J0VHR2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0060 family.
messages: Cell membrane

1897729:BOX17 RS02105
gene id: 1897729:BOX17_RS02105
uniprot id: A0A1J0VCY7
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1897729:BOX17 RS02930
gene id: 1897729:BOX17_RS02930
uniprot id: A0A1J0VD90
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the gamma-glutamyltransferase family.
messages: Cleaved by autocatalysis into a large and a small subunit.
messages: This enzyme consists of two polypeptide chains, which are synthesized in precursor form from a single polypeptide.

1897729:BOX17 RS13685
gene id: 1897729:BOX17_RS13685
uniprot id: A0A1J0VIM7
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1897729:BOX17 RS17165
gene id: 1897729:BOX17_RS17165
uniprot id: A0A1J0VFZ8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiK family.
messages: Cytoplasm
messages: Required for efficient ubiquinone (coenzyme Q) biosynthesis. UbiK is probably an accessory factor of Ubi enzymes and facilitates ubiquinone biosynthesis by acting as an assembly factor, a targeting factor, or both.

1897729:BOX17 RS05550
gene id: 1897729:BOX17_RS05550
uniprot id: A0A1J0VEI9
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 2 residues (Tyr-58 and Arg-61) present in a large hydrophobic pocket are probably involved in substrate specificity. They are important for desuccinylation activity, but dispensable for deacetylation activity.
messages: Belongs to the sirtuin family. Class III subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form.

1897729:BOX17 RS02125
gene id: 1897729:BOX17_RS02125
uniprot id: A0A1J0VCV3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

1897729:BOX17 RS15600
gene id: 1897729:BOX17_RS15600
uniprot id: A0A1J0VJN1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NfuA family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is presumably bound at the interface of two monomers.
messages: Homodimer.
messages: Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins.

1897729:BOX17 RS07925
gene id: 1897729:BOX17_RS07925
uniprot id: A0A1J0VFR0
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

1897729:BOX17 RS02305
gene id: 1897729:BOX17_RS02305
uniprot id: A0A1J0VD19
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1897729:BOX17 RS15825
gene id: 1897729:BOX17_RS15825
uniprot id: A0A1J0VKS7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ExbB/TolQ family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

1897729:BOX17 RS07575
gene id: 1897729:BOX17_RS07575
uniprot id: A0A1J0VFJ9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

1897729:BOX17 RS02065
gene id: 1897729:BOX17_RS02065
uniprot id: A0A1J0VCV1
names: Similarity
messages: Belongs to the glutamine synthetase family.

1897729:BOX17 RS15810
gene id: 1897729:BOX17_RS15810
uniprot id: A0A1J0VJS0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TolB family.
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: Periplasm
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

1897729:BOX17 RS08290
gene id: 1897729:BOX17_RS08290
uniprot id: A0A1J0VFY9
names: Similarity
messages: Belongs to the P(II) protein family.

1897729:BOX17 RS10995
gene id: 1897729:BOX17_RS10995
uniprot id: A0A1J0VHC3
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transglycosylase Slt family.
messages: Cell outer membrane
messages: In the C-terminal section; belongs to the transglycosylase Slt family.
messages: In the N-terminal section; belongs to the bacterial solute-binding protein 3 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella.
messages: The N-terminal domain does not have lytic activity and probably modulates enzymatic activity. The C-terminal domain is the catalytic active domain.

1897729:BOX17 RS01175
gene id: 1897729:BOX17_RS01175
uniprot id: A0A1J0VCC6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.
messages: Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.
messages: Cytoplasm
messages: Homodimer.

1897729:BOX17 RS12605
gene id: 1897729:BOX17_RS12605
uniprot id: A0A1J0VI42
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1897729:BOX17 RS12955
gene id: 1897729:BOX17_RS12955
uniprot id: A0A1J0VIB0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the R-transferase family. Bpt subfamily.
messages: Cytoplasm
messages: Functions in the N-end rule pathway of protein degradation where it conjugates Leu from its aminoacyl-tRNA to the N-termini of proteins containing an N-terminal aspartate or glutamate.

1897729:BOX17 RS02840
gene id: 1897729:BOX17_RS02840
uniprot id: A0A1J0VD70
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1897729:BOX17 RS01945
gene id: 1897729:BOX17_RS01945
uniprot id: A0A1J0VCT2
names: Function
names: Similarity
messages: Belongs to the ABC transporter superfamily. Outer membrane lipopolysaccharide export (TC 1.B.42) family.
messages: Part of the ABC transporter complex LptBFG involved in the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane. Probably responsible for energy coupling to the transport system.

1897729:BOX17 RS10985
gene id: 1897729:BOX17_RS10985
uniprot id: A0A1J0VHA5
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

1897729:BOX17 RS13265
gene id: 1897729:BOX17_RS13265
uniprot id: A0A1J0VII0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

1897729:BOX17 RS08850
gene id: 1897729:BOX17_RS08850
uniprot id: A0A1J0VG94
names: Similarity
messages: Belongs to the YggT family.

1897729:BOX17 RS08615
gene id: 1897729:BOX17_RS08615
uniprot id: A0A1J0VG44
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

1897729:BOX17 RS12715
gene id: 1897729:BOX17_RS12715
uniprot id: A0A1J0VI51
names: Function
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).

1897729:BOX17 RS12700
gene id: 1897729:BOX17_RS12700
uniprot id: A0A1J0VI60
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
messages: Cell inner membrane
messages: Membrane

1897729:BOX17 RS14025
gene id: 1897729:BOX17_RS14025
uniprot id: A0A1J0VIV2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transpeptidase family. MrdA subfamily.
messages: Catalyzes cross-linking of the peptidoglycan cell wall.
messages: Cell inner membrane

1897729:BOX17 RS09920
gene id: 1897729:BOX17_RS09920
uniprot id: A0A1J0VGT5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

1897729:BOX17 RS09030
gene id: 1897729:BOX17_RS09030
uniprot id: A0A1J0VGA2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

1897729:BOX17 RS16145
gene id: 1897729:BOX17_RS16145
uniprot id: A0A1J0VJV9
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

1897729:BOX17 RS04540
gene id: 1897729:BOX17_RS04540
uniprot id: A0A1J0VE19
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

1897729:BOX17 RS01390
gene id: 1897729:BOX17_RS01390
uniprot id: A0A1J0VCG6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

1897729:BOX17 RS11990
gene id: 1897729:BOX17_RS11990
uniprot id: A0A1J0VHT3
names: Function
names: Similarity
messages: Belongs to the peroxiredoxin family. Prx5 subfamily.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

1897729:BOX17 RS04365
gene id: 1897729:BOX17_RS04365
uniprot id: A0A1J0VE40
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

1897729:BOX17 RS02540
gene id: 1897729:BOX17_RS02540
uniprot id: A0A1J0VD28
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

1897729:BOX17 RS14750
gene id: 1897729:BOX17_RS14750
uniprot id: A0A1J0VJ80
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1897729:BOX17 RS13380
gene id: 1897729:BOX17_RS13380
uniprot id: A0A1J0VKQ0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phospholipase A1 family.
messages: Binds 1 Ca(2+) ion per monomer. In the dimeric form the Ca(2+) is bound by different amino acids with binding of each Ca(2+) shared with ligands coming from each monomer. The Ca(2+) ion may have a role in catalysis.
messages: Cell outer membrane
messages: Homodimer; dimerization is reversible, and the dimeric form is the active one.
messages: Hydrolysis of phosphatidylcholine with phospholipase A2 (EC 3.1.1.4) and phospholipase A1 (EC 3.1.1.32) activities.
messages: Membrane

1897729:BOX17 RS01655
gene id: 1897729:BOX17_RS01655
uniprot id: A0A1J0VCM7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

1897729:BOX17 RS11530
gene id: 1897729:BOX17_RS11530
uniprot id: A0A1J0VHL7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

1897729:BOX17 RS08755
gene id: 1897729:BOX17_RS08755
uniprot id: A0A1J0VG70
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

1897729:BOX17 RS04290
gene id: 1897729:BOX17_RS04290
uniprot id: A0A1J0VDY9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell inner membrane
messages: Membrane

1897729:BOX17 RS09880
gene id: 1897729:BOX17_RS09880
uniprot id: A0A1J0VGS7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoH subfamily.
messages: Cytoplasm
messages: Interacts with the RNA polymerase core enzyme.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes.

1897729:BOX17 RS08185
gene id: 1897729:BOX17_RS08185
uniprot id: A0A1J0VFV6
names: Similarity
messages: Belongs to the UPF0301 (AlgH) family.

1897729:BOX17 RS06100
gene id: 1897729:BOX17_RS06100
uniprot id: A0A1J0VKB9
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

1897729:BOX17 RS01280
gene id: 1897729:BOX17_RS01280
uniprot id: A0A1J0VCH2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Membrane

1897729:BOX17 RS13440
gene id: 1897729:BOX17_RS13440
uniprot id: A0A1J0VIH6
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit B family.

1897729:BOX17 RS02015
gene id: 1897729:BOX17_RS02015
uniprot id: A0A1J0VCX2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

1897729:BOX17 RS13410
gene id: 1897729:BOX17_RS13410
uniprot id: A0A1J0VKP5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Membrane

1897729:BOX17 RS08690
gene id: 1897729:BOX17_RS08690
uniprot id: A0A1J0VG39
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

1897729:BOX17 RS13905
gene id: 1897729:BOX17_RS13905
uniprot id: A0A1J0VIS8
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family.
messages: Homopolymer.

1897729:BOX17 RS09760
gene id: 1897729:BOX17_RS09760
uniprot id: A0A1J0VGN3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

1897729:BOX17 RS10540
gene id: 1897729:BOX17_RS10540
uniprot id: A0A1J0VH21
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetyltransferase family. ArgA subfamily.
messages: Cytoplasm
messages: In bacteria which possess the bifunctional enzyme ornithine acetyltransferase/N-acetylglutamate synthase (ArgJ), ArgA fulfills an anaplerotic role.

1897729:BOX17 RS05600
gene id: 1897729:BOX17_RS05600
uniprot id: A0A1J0VEL4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptF/LptG family.
messages: Component of the lipopolysaccharide transport and assembly complex. The LptBFG transporter is composed of two ATP-binding proteins (LptB) and two transmembrane proteins (LptF and LptG).
messages: Membrane
messages: Part of the ABC transporter complex LptBFG involved in the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane.

1897729:BOX17 RS14440
gene id: 1897729:BOX17_RS14440
uniprot id: A0A1J0VJ33
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the urease beta subunit family.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

1897729:BOX17 RS08225
gene id: 1897729:BOX17_RS08225
uniprot id: A0A1J0VKI2
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

1897729:BOX17 RS03515
gene id: 1897729:BOX17_RS03515
uniprot id: A0A1J0VDJ6
names: Similarity
messages: Belongs to the glutamate--cysteine ligase type 1 family. Type 1 subfamily.

1897729:BOX17 RS02460
gene id: 1897729:BOX17_RS02460
uniprot id: A0A1J0VD14
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Catalyzes the sodium-dependent uptake of extracellular L-proline.
messages: Cell inner membrane
messages: Membrane

1897729:BOX17 RS09430
gene id: 1897729:BOX17_RS09430
uniprot id: A0A1J0VGK6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1897729:BOX17 RS15520
gene id: 1897729:BOX17_RS15520
uniprot id: A0A1J0VJL5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FdhD family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH.

1897729:BOX17 RS06890
gene id: 1897729:BOX17_RS06890
uniprot id: A0A1J0VFB0
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1897729:BOX17 RS04695
gene id: 1897729:BOX17_RS04695
uniprot id: A0A1J0VKB8
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

1897729:BOX17 RS09020
gene id: 1897729:BOX17_RS09020
uniprot id: A0A1J0VGB3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1897729:BOX17 RS05635
gene id: 1897729:BOX17_RS05635
uniprot id: A0A1J0VER5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DoxX family.
messages: Membrane

1897729:BOX17 RS09175
gene id: 1897729:BOX17_RS09175
uniprot id: A0A1J0VGF3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

1897729:BOX17 RS04605
gene id: 1897729:BOX17_RS04605
uniprot id: A0A1J0VE14
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Membrane

1897729:BOX17 RS01130
gene id: 1897729:BOX17_RS01130
uniprot id: A0A1J0VK68
names: Subcellular Location Annotation
messages: Membrane

1897729:BOX17 RS02560
gene id: 1897729:BOX17_RS02560
uniprot id: A0A1J0VD37
names: Function
names: Similarity
messages: Belongs to the ketopantoate reductase family.
messages: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.

1897729:BOX17 RS01735
gene id: 1897729:BOX17_RS01735
uniprot id: A0A1J0VCP4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

1897729:BOX17 RS15465
gene id: 1897729:BOX17_RS15465
uniprot id: A0A1J0VJH9
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

1897729:BOX17 RS13690
gene id: 1897729:BOX17_RS13690
uniprot id: A0A1J0VH00
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GcdB/MmdB/OadB family.
messages: Catalyzes the decarboxylation of oxaloacetate coupled to Na(+) translocation.
messages: Cell membrane
messages: Heterotrimer of an alpha, a beta and a gamma subunit.
messages: Membrane

1897729:BOX17 RS07710
gene id: 1897729:BOX17_RS07710
uniprot id: A0A1J0VFM5
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

1897729:BOX17 RS01310
gene id: 1897729:BOX17_RS01310
uniprot id: A0A1J0VCF2
names: Function
names: Similarity
messages: Belongs to the class-I DAHP synthase family.
messages: Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP).

1897729:BOX17 RS07480
gene id: 1897729:BOX17_RS07480
uniprot id: A0A1J0VFM6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MntP (TC 9.B.29) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Probably functions as a manganese efflux pump.

1897729:BOX17 RS14785
gene id: 1897729:BOX17_RS14785
uniprot id: A0A1J0VJ86
names: Similarity
messages: Belongs to the YkuD family.

1897729:BOX17 RS07905
gene id: 1897729:BOX17_RS07905
uniprot id: A0A1J0VFS2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the N7 position of guanine in position 527 of 16S rRNA.

1897729:BOX17 RS08190
gene id: 1897729:BOX17_RS08190
uniprot id: A0A1J0VFV5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

1897729:BOX17 RS13375
gene id: 1897729:BOX17_RS13375
uniprot id: A0A1J0VIG2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ElaB/YgaM/YqjD family.
messages: Cell inner membrane
messages: Membrane

1897729:BOX17 RS15655
gene id: 1897729:BOX17_RS15655
uniprot id: A0A1J0VJP2
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1897729:BOX17 RS02850
gene id: 1897729:BOX17_RS02850
uniprot id: A0A1J0VDA8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

1897729:BOX17 RS01255
gene id: 1897729:BOX17_RS01255
uniprot id: A0A1J0VCH7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Cytoplasm
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

1897729:BOX17 RS09415
gene id: 1897729:BOX17_RS09415
uniprot id: A0A1J0VGH7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

1897729:BOX17 RS07850
gene id: 1897729:BOX17_RS07850
uniprot id: A0A1J0VFN7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

1897729:BOX17 RS15260
gene id: 1897729:BOX17_RS15260
uniprot id: A0A1J0VJG6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

1897729:BOX17 RS07910
gene id: 1897729:BOX17_RS07910
uniprot id: A0A1J0VFR8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

1897729:BOX17 RS12015
gene id: 1897729:BOX17_RS12015
uniprot id: A0A1J0VHV5
names: Subcellular Location Annotation
messages: Membrane

1897729:BOX17 RS07255
gene id: 1897729:BOX17_RS07255
uniprot id: A0A1J0VFE0
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Monomer.

1897729:BOX17 RS16180
gene id: 1897729:BOX17_RS16180
uniprot id: A0A1J0VJY6
names: Subcellular Location Annotation
messages: Membrane

1897729:BOX17 RS10030
gene id: 1897729:BOX17_RS10030
uniprot id: A0A1J0VGT1
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Inhibited by UTP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1897729:BOX17 RS08795
gene id: 1897729:BOX17_RS08795
uniprot id: A0A1J0VG80
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1897729:BOX17 RS12775
gene id: 1897729:BOX17_RS12775
uniprot id: A0A1J0VIA1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1897729:BOX17 RS13450
gene id: 1897729:BOX17_RS13450
uniprot id: A0A1J0VIL4
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

1897729:BOX17 RS10755
gene id: 1897729:BOX17_RS10755
uniprot id: A0A1J0VH77
names: Function
names: Similarity
messages: Belongs to the HypA/HybF family.
messages: Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.

1897729:BOX17 RS09900
gene id: 1897729:BOX17_RS09900
uniprot id: A0A1J0VGQ8
names: Caution
names: Function
names: Similarity
messages: Belongs to the dUTPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

1897729:BOX17 RS01345
gene id: 1897729:BOX17_RS01345
uniprot id: A0A1J0VCF6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

1897729:BOX17 RS10390
gene id: 1897729:BOX17_RS10390
uniprot id: A0A1J0VH03
names: Similarity
messages: Belongs to the IMPACT family.

1897729:BOX17 RS05125
gene id: 1897729:BOX17_RS05125
uniprot id: A0A1J0VEB2
names: Subcellular Location Annotation
messages: Membrane

1897729:BOX17 RS08180
gene id: 1897729:BOX17_RS08180
uniprot id: A0A1J0VG01
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

1897729:BOX17 RS08375
gene id: 1897729:BOX17_RS08375
uniprot id: A0A1J0VFY4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

1897729:BOX17 RS10160
gene id: 1897729:BOX17_RS10160
uniprot id: A0A1J0VGW0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell membrane
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

1897729:BOX17 RS14155
gene id: 1897729:BOX17_RS14155
uniprot id: A0A1J0VIX4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: Membrane
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

1897729:BOX17 RS03280
gene id: 1897729:BOX17_RS03280
uniprot id: A0A1J0VDE1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Cytoplasm
messages: Homodimer.

1897729:BOX17 RS11870
gene id: 1897729:BOX17_RS11870
uniprot id: A0A1J0VHQ9
names: Function
names: Similarity
messages: Belongs to the gamma-glutamylcyclotransferase family.
messages: Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides.

1897729:BOX17 RS00030
gene id: 1897729:BOX17_RS00030
uniprot id: A0A1J0VBS6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DEAD box helicase family. RhlE subfamily.
messages: Cytoplasm
messages: DEAD-box RNA helicase involved in ribosome assembly. Has RNA-dependent ATPase activity and unwinds double-stranded RNA.

1897729:BOX17 RS06295
gene id: 1897729:BOX17_RS06295
uniprot id: A0A1J0VEY4
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

1897729:BOX17 RS06640
gene id: 1897729:BOX17_RS06640
uniprot id: A0A1J0VF34
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1897729:BOX17 RS00625
gene id: 1897729:BOX17_RS00625
uniprot id: A0A1J0VC36
names: Similarity
messages: Belongs to the bacterial solute-binding protein 5 family.

1897729:BOX17 RS00965
gene id: 1897729:BOX17_RS00965
uniprot id: A0A1J0VC92
names: Subcellular Location Annotation
messages: Membrane

1897729:BOX17 RS10275
gene id: 1897729:BOX17_RS10275
uniprot id: A0A1J0VGZ9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
messages: Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).
messages: Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
messages: Cytoplasm

1897729:BOX17 RS13480
gene id: 1897729:BOX17_RS13480
uniprot id: A0A1J0VII1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

1897729:BOX17 RS02150
gene id: 1897729:BOX17_RS02150
uniprot id: A0A1J0VCZ4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein PotD/PotF family.
messages: Periplasm
messages: Required for the activity of the bacterial periplasmic transport system of putrescine.

1897729:BOX17 RS06580
gene id: 1897729:BOX17_RS06580
uniprot id: A0A1J0VF26
names: Similarity
messages: Belongs to the HMG-CoA lyase family.

1897729:BOX17 RS03560
gene id: 1897729:BOX17_RS03560
uniprot id: A0A1J0VKA8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1897729:BOX17 RS12555
gene id: 1897729:BOX17_RS12555
uniprot id: A0A1J0VKQ1
names: Similarity
messages: Belongs to the CmpA/NrtA family.

1897729:BOX17 RS01730
gene id: 1897729:BOX17_RS01730
uniprot id: A0A1J0VCN3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsQ/DivIB family. FtsQ subfamily.
messages: Cell inner membrane
messages: Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly.
messages: Part of a complex composed of FtsB, FtsL and FtsQ.

1897729:BOX17 RS13630
gene id: 1897729:BOX17_RS13630
uniprot id: A0A1J0VIL9
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1897729:BOX17 RS12155
gene id: 1897729:BOX17_RS12155
uniprot id: A0A1J0VHW6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

1897729:BOX17 RS09425
gene id: 1897729:BOX17_RS09425
uniprot id: A0A1J0VGJ4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

1897729:BOX17 RS07015
gene id: 1897729:BOX17_RS07015
uniprot id: A0A1J0VFA8
names: Function
names: Similarity
messages: Belongs to the MoaB/Mog family.
messages: May be involved in the biosynthesis of molybdopterin.

1897729:BOX17 RS14015
gene id: 1897729:BOX17_RS14015
uniprot id: A0A1J0VIS7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein uL14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein uL14 (rplN).

1897729:BOX17 RS07675
gene id: 1897729:BOX17_RS07675
uniprot id: A0A1J0VFP9
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

1897729:BOX17 RS01195
gene id: 1897729:BOX17_RS01195
uniprot id: A0A1J0VCC8
names: Subcellular Location Annotation
messages: Membrane

1897729:BOX17 RS02860
gene id: 1897729:BOX17_RS02860
uniprot id: A0A1J0VD66
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1897729:BOX17 RS01930
gene id: 1897729:BOX17_RS01930
uniprot id: A0A1J0VCR8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the KdsC family.
messages: Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate.
messages: Homotetramer.

1897729:BOX17 RS10920
gene id: 1897729:BOX17_RS10920
uniprot id: A0A1J0VH87
names: Subcellular Location Annotation
messages: Membrane

1897729:BOX17 RS09255
gene id: 1897729:BOX17_RS09255
uniprot id: A0A1J0VGH3
names: Cofactor
names: Similarity
messages: Belongs to the DNA photolyase class-1 family.
messages: Belongs to the DNA photolyase family.
messages: Binds 1 FAD per subunit.

1897729:BOX17 RS12295
gene id: 1897729:BOX17_RS12295
uniprot id: A0A1J0VKN7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the GTP cyclohydrolase II family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.

1897729:BOX17 RS15480
gene id: 1897729:BOX17_RS15480
uniprot id: A0A1J0VJK8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the formate dehydrogenase gamma subunit family.
messages: Membrane

1897729:BOX17 RS12235
gene id: 1897729:BOX17_RS12235
uniprot id: A0A1J0VHX9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Mg(2+). Can also accept Mn(2+).

1897729:BOX17 RS00600
gene id: 1897729:BOX17_RS00600
uniprot id: A0A1J0VC29
names: Similarity
messages: Belongs to the RutC family.

1897729:BOX17 RS07795
gene id: 1897729:BOX17_RS07795
uniprot id: A0A1J0VFT1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

1897729:BOX17 RS04015
gene id: 1897729:BOX17_RS04015
uniprot id: A0A1J0VKC8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1897729:BOX17 RS08710
gene id: 1897729:BOX17_RS08710
uniprot id: A0A1J0VG79
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

1897729:BOX17 RS14065
gene id: 1897729:BOX17_RS14065
uniprot id: A0A1J0VIW0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1897729:BOX17 RS09785
gene id: 1897729:BOX17_RS09785
uniprot id: A0A1J0VGP8
names: Similarity
messages: Belongs to the threonine synthase family.

1897729:BOX17 RS16170
gene id: 1897729:BOX17_RS16170
uniprot id: A0A1J0VJX3
names: Subcellular Location Annotation
messages: Membrane

1897729:BOX17 RS09945
gene id: 1897729:BOX17_RS09945
uniprot id: A0A1J0VGR4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm
messages: Homodimer.

1897729:BOX17 RS00585
gene id: 1897729:BOX17_RS00585
uniprot id: A0A1J0VC26
names: Function
names: Similarity
messages: Acts on leucine, isoleucine and valine.
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

1897729:BOX17 RS02925
gene id: 1897729:BOX17_RS02925
uniprot id: A0A1J0VD86
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

1897729:BOX17 RS11240
gene id: 1897729:BOX17_RS11240
uniprot id: A0A1J0VHE1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

1897729:BOX17 RS03045
gene id: 1897729:BOX17_RS03045
uniprot id: A0A1J0VDA2
names: Function
names: Similarity
messages: Belongs to the AlaDH/PNT family.
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

1897729:BOX17 RS08960
gene id: 1897729:BOX17_RS08960
uniprot id: A0A1J0VGA5
names: Caution
names: Function
names: Similarity
messages: Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon.
messages: Belongs to the biotin--protein ligase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1897729:BOX17 RS08215
gene id: 1897729:BOX17_RS08215
uniprot id: A0A1J0VKH5
names: Function
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

1897729:BOX17 RS08040
gene id: 1897729:BOX17_RS08040
uniprot id: A0A1J0VFY0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1897729:BOX17 RS09165
gene id: 1897729:BOX17_RS09165
uniprot id: A0A1J0VGF6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

1897729:BOX17 RS10570
gene id: 1897729:BOX17_RS10570
uniprot id: A0A1J0VH52
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

1897729:BOX17 RS12855
gene id: 1897729:BOX17_RS12855
uniprot id: A0A1J0VIB4
names: Subcellular Location Annotation
messages: Membrane

1897729:BOX17 RS10750
gene id: 1897729:BOX17_RS10750
uniprot id: A0A1J0VH74
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. HypB/HupM subfamily.

1897729:BOX17 RS00240
gene id: 1897729:BOX17_RS00240
uniprot id: A0A1J0VBX8
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS1 family.
messages: Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence.

1897729:BOX17 RS12180
gene id: 1897729:BOX17_RS12180
uniprot id: A0A1J0VHV9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.
messages: Homodimer.
messages: The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis.

1897729:BOX17 RS10295
gene id: 1897729:BOX17_RS10295
uniprot id: A0A1J0VGY7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KdsA family.
messages: Cytoplasm

1897729:BOX17 RS14735
gene id: 1897729:BOX17_RS14735
uniprot id: A0A1J0VJ63
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

1897729:BOX17 RS05495
gene id: 1897729:BOX17_RS05495
uniprot id: A0A1J0VEK0
names: Similarity
messages: Belongs to the DprA/Smf family.

1897729:BOX17 RS15375
gene id: 1897729:BOX17_RS15375
uniprot id: A0A1J0VJG5
names: Similarity
messages: Belongs to the Nudix hydrolase family.

1897729:BOX17 RS00810
gene id: 1897729:BOX17_RS00810
uniprot id: A0A1J0VC67
names: Similarity
messages: Belongs to the Gfa family.

1897729:BOX17 RS04800
gene id: 1897729:BOX17_RS04800
uniprot id: A0A1J0VE84
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0). The b'-subunit is a diverged and duplicated form of b found in plants and photosynthetic bacteria.
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

1897729:BOX17 RS08950
gene id: 1897729:BOX17_RS08950
uniprot id: A0A1J0VGB5
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

1897729:BOX17 RS06480
gene id: 1897729:BOX17_RS06480
uniprot id: A0A1J0VF11
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

1897729:BOX17 RS00010
gene id: 1897729:BOX17_RS00010
uniprot id: A0A1J0VBT1
names: Subcellular Location Annotation
messages: Membrane

1897729:BOX17 RS07930
gene id: 1897729:BOX17_RS07930
uniprot id: A0A1J0VFR1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HesB/IscA family.
messages: Binds 1 iron-sulfur cluster per subunit.
messages: Homodimer.
messages: Required for insertion of 4Fe-4S clusters for at least IspG.

1897729:BOX17 RS09940
gene id: 1897729:BOX17_RS09940
uniprot id: A0A1J0VGR6
names: Similarity
messages: Belongs to the AlaDH/PNT family.

1897729:BOX17 RS07645
gene id: 1897729:BOX17_RS07645
uniprot id: A0A1J0VFP4
names: Cofactor
messages: Probably binds two magnesium or manganese ions per subunit.

1897729:BOX17 RS08035
gene id: 1897729:BOX17_RS08035
uniprot id: A0A1J0VFV2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1897729:BOX17 RS09115
gene id: 1897729:BOX17_RS09115
uniprot id: A0A1J0VGB8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

1897729:BOX17 RS11950
gene id: 1897729:BOX17_RS11950
uniprot id: A0A1J0VHS6
names: Subcellular Location Annotation
messages: Membrane

1897729:BOX17 RS08800
gene id: 1897729:BOX17_RS08800
uniprot id: A0A1J0VG93
names: Similarity
messages: Belongs to the SfsA family.

1897729:BOX17 RS00335
gene id: 1897729:BOX17_RS00335
uniprot id: A0A1J0VBZ6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThiI family.
messages: Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1897729:BOX17 RS04430
gene id: 1897729:BOX17_RS04430
uniprot id: A0A1J0VE13
names: Subunit
messages: Homodimer.

1897729:BOX17 RS08170
gene id: 1897729:BOX17_RS08170
uniprot id: A0A1J0VFX1
names: Similarity
messages: Belongs to the CvfB family.

1897729:BOX17 RS16140
gene id: 1897729:BOX17_RS16140
uniprot id: A0A1J0VJX1
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

1897729:BOX17 RS06570
gene id: 1897729:BOX17_RS06570
uniprot id: A0A1J0VF66
names: Similarity
messages: Belongs to the UPF0065 (bug) family.

1897729:BOX17 RS14850
gene id: 1897729:BOX17_RS14850
uniprot id: A0A1J0VJ95
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BexD/CtrA/VexA family.
messages: Cell outer membrane
messages: Membrane

1897729:BOX17 RS08720
gene id: 1897729:BOX17_RS08720
uniprot id: A0A1J0VG73
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

1897729:BOX17 RS00355
gene id: 1897729:BOX17_RS00355
uniprot id: A0A1J0VC07
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

1897729:BOX17 RS04925
gene id: 1897729:BOX17_RS04925
uniprot id: A0A1J0VE89
names: Function
names: Similarity
messages: Belongs to the SELO family.
messages: Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr or Tyr residues of target proteins (AMPylation).

1897729:BOX17 RS09955
gene id: 1897729:BOX17_RS09955
uniprot id: A0A1J0VGT8
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

1897729:BOX17 RS06970
gene id: 1897729:BOX17_RS06970
uniprot id: A0A1J0VFE1
names: Similarity
messages: Belongs to the arginase family. Agmatinase subfamily.

1897729:BOX17 RS05595
gene id: 1897729:BOX17_RS05595
uniprot id: A0A1J0VEJ7
names: Subcellular Location Annotation
messages: Membrane

1897729:BOX17 RS08495
gene id: 1897729:BOX17_RS08495
uniprot id: A0A1J0VG32
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HMBS family.
messages: Binds 1 dipyrromethane group covalently.
messages: Monomer.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
messages: The porphobilinogen subunits are added to the dipyrromethane group.

1897729:BOX17 RS15970
gene id: 1897729:BOX17_RS15970
uniprot id: A0A1J0VJS7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

1897729:BOX17 RS05915
gene id: 1897729:BOX17_RS05915
uniprot id: A0A1J0VEU2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1897729:BOX17 RS08300
gene id: 1897729:BOX17_RS08300
uniprot id: A0A1J0VFZ4
names: Similarity
messages: Belongs to the P(II) protein family.

1897729:BOX17 RS05490
gene id: 1897729:BOX17_RS05490
uniprot id: A0A1J0VEH7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SUA5 family. TsaC subfamily.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Catalyzes the conversion of L-threonine, HCO(3)(-)/CO(2) and ATP to give threonylcarbamoyl-AMP (TC-AMP) as the acyladenylate intermediate, with the release of diphosphate.

1897729:BOX17 RS09745
gene id: 1897729:BOX17_RS09745
uniprot id: A0A1J0VGP0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. SRP is a ribonucleoprotein composed of Ffh and a 4.5S RNA molecule.

1897729:BOX17 RS02020
gene id: 1897729:BOX17_RS02020
uniprot id: A0A1J0VCU1
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

1897729:BOX17 RS13895
gene id: 1897729:BOX17_RS13895
uniprot id: A0A1J0VIT3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response.
messages: Belongs to the SrkA/RdoA protein kinase family.
messages: Cytoplasm
messages: Monomer.

1897729:BOX17 RS14715
gene id: 1897729:BOX17_RS14715
uniprot id: A0A1J0VJ51
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. MoaA family.
messages: Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.
messages: Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
messages: Monomer and homodimer.

1897729:BOX17 RS09060
gene id: 1897729:BOX17_RS09060
uniprot id: A0A1J0VGC2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

1897729:BOX17 RS13770
gene id: 1897729:BOX17_RS13770
uniprot id: A0A1J0VIQ5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

1897729:BOX17 RS07490
gene id: 1897729:BOX17_RS07490
uniprot id: A0A1J0VFH8
names: Subcellular Location Annotation
messages: Membrane

1897729:BOX17 RS05865
gene id: 1897729:BOX17_RS05865
uniprot id: A0A1J0VEP5
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1897729:BOX17 RS15025
gene id: 1897729:BOX17_RS15025
uniprot id: A0A1J0VJA0
names: Subcellular Location Annotation
messages: Membrane

1897729:BOX17 RS08875
gene id: 1897729:BOX17_RS08875
uniprot id: A0A1J0VGA9
names: Function
names: Similarity
messages: Belongs to the anhydro-N-acetylmuramic acid kinase family.
messages: Catalyzes the specific phosphorylation of 1,6-anhydro-N-acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling.

1897729:BOX17 RS15735
gene id: 1897729:BOX17_RS15735
uniprot id: A0A1J0VJQ5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M24B family. Bacterial-type prolidase subfamily.
messages: Binds 2 manganese ions per subunit.
messages: Splits dipeptides with a prolyl residue in the C-terminal position.

1897729:BOX17 RS03535
gene id: 1897729:BOX17_RS03535
uniprot id: A0A1J0VDI8
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HSP33 family.
messages: Cytoplasm
messages: Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress.
messages: Under oxidizing conditions two disulfide bonds are formed involving the reactive cysteines. Under reducing conditions zinc is bound to the reactive cysteines and the protein is inactive.

1897729:BOX17 RS10455
gene id: 1897729:BOX17_RS10455
uniprot id: A0A1J0VH29
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1897729:BOX17 RS13745
gene id: 1897729:BOX17_RS13745
uniprot id: A0A1J0VIM9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1897729:BOX17 RS08090
gene id: 1897729:BOX17_RS08090
uniprot id: A0A1J0VFU0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase group 1 family.
messages: Cell membrane
messages: Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP-Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A.

1897729:BOX17 RS08995
gene id: 1897729:BOX17_RS08995
uniprot id: A0A1J0VG95
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

1897729:BOX17 RS01660
gene id: 1897729:BOX17_RS01660
uniprot id: A0A1J0VCL7
names: Subcellular Location Annotation
messages: Membrane

1897729:BOX17 RS01795
gene id: 1897729:BOX17_RS01795
uniprot id: A0A1J0VCP6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

1897729:BOX17 RS08660
gene id: 1897729:BOX17_RS08660
uniprot id: A0A1J0VG72
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

1897729:BOX17 RS02005
gene id: 1897729:BOX17_RS02005
uniprot id: A0A1J0VCS2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MreD family.
messages: Cell inner membrane
messages: Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins.
messages: Membrane

1897729:BOX17 RS14450
gene id: 1897729:BOX17_RS14450
uniprot id: A0A1J0VJ24
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UreE family.
messages: Cytoplasm
messages: Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly.

1897729:BOX17 RS06095
gene id: 1897729:BOX17_RS06095
uniprot id: A0A1J0VET8
names: Function
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.

1897729:BOX17 RS02810
gene id: 1897729:BOX17_RS02810
uniprot id: A0A1J0VD63
names: Similarity
messages: Belongs to the citrate synthase family.

1897729:BOX17 RS12875
gene id: 1897729:BOX17_RS12875
uniprot id: A0A1J0VIA5
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

1897729:BOX17 RS11930
gene id: 1897729:BOX17_RS11930
uniprot id: A0A1J0VHU1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1897729:BOX17 RS15455
gene id: 1897729:BOX17_RS15455
uniprot id: A0A1J0VJJ8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dsrC/tusE family.
messages: Cytoplasm
messages: Part of a sulfur-relay system.

1897729:BOX17 RS09805
gene id: 1897729:BOX17_RS09805
uniprot id: A0A1J0VKH6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

1897729:BOX17 RS15295
gene id: 1897729:BOX17_RS15295
uniprot id: A0A1J0VJE8
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1897729:BOX17 RS13420
gene id: 1897729:BOX17_RS13420
uniprot id: A0A1J0VIH9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

1897729:BOX17 RS11710
gene id: 1897729:BOX17_RS11710
uniprot id: A0A1J0VHQ1
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1897729:BOX17 RS10230
gene id: 1897729:BOX17_RS10230
uniprot id: A0A1J0VGZ0
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

1897729:BOX17 RS09010
gene id: 1897729:BOX17_RS09010
uniprot id: A0A1J0VGC3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1897729:BOX17 RS13340
gene id: 1897729:BOX17_RS13340
uniprot id: A0A1J0VIF8
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1897729:BOX17 RS01805
gene id: 1897729:BOX17_RS01805
uniprot id: A0A1J0VCN2
names: Similarity
messages: Belongs to the UPF0102 family.

1897729:BOX17 RS15440
gene id: 1897729:BOX17_RS15440
uniprot id: A0A1J0VJI1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DsrE/TusD family.
messages: Cytoplasm

1897729:BOX17 RS08625
gene id: 1897729:BOX17_RS08625
uniprot id: A0A1J0VG51
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Mediates influx of magnesium ions.
messages: Membrane

1897729:BOX17 RS13455
gene id: 1897729:BOX17_RS13455
uniprot id: A0A1J0VIJ1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1897729:BOX17 RS03990
gene id: 1897729:BOX17_RS03990
uniprot id: A0A1J0VDX5
names: Similarity
messages: Belongs to the band 7/mec-2 family.

1897729:BOX17 RS07580
gene id: 1897729:BOX17_RS07580
uniprot id: A0A1J0VFN5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

1897729:BOX17 RS07885
gene id: 1897729:BOX17_RS07885
uniprot id: A0A1J0VFQ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase A chain family.
messages: Cell membrane
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

1897729:BOX17 RS00575
gene id: 1897729:BOX17_RS00575
uniprot id: A0A1J0VC41
names: Subcellular Location Annotation
messages: Membrane

1897729:BOX17 RS01810
gene id: 1897729:BOX17_RS01810
uniprot id: A0A1J0VCP3
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SIS family. GmhA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate.
messages: Cytoplasm
messages: Homotetramer.
messages: The reaction produces a racemic mixture of D-glycero-alpha-D-manno-heptose 7-phosphate and D-glycero-beta-D-manno-heptose 7-phosphate.

1897729:BOX17 RS02995
gene id: 1897729:BOX17_RS02995
uniprot id: A0A1J0VD94
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmB subfamily.
messages: Methylates ribosomal protein uL3 on a specific glutamine residue.

1897729:BOX17 RS03815
gene id: 1897729:BOX17_RS03815
uniprot id: A0A1J0VDQ9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoS subfamily.
messages: Cytoplasm
messages: Interacts with the RNA polymerase core enzyme.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the master transcriptional regulator of the stationary phase and the general stress response.

1897729:BOX17 RS05370
gene id: 1897729:BOX17_RS05370
uniprot id: A0A1J0VEF1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YajC family.
messages: Cell inner membrane
messages: Membrane

1897729:BOX17 RS14890
gene id: 1897729:BOX17_RS14890
uniprot id: A0A1J0VJA2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
messages: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.
messages: Homodimer.

1897729:BOX17 RS08410
gene id: 1897729:BOX17_RS08410
uniprot id: A0A1J0VG11
names: Similarity
messages: Belongs to the universal stress protein A family.

1897729:BOX17 RS02885
gene id: 1897729:BOX17_RS02885
uniprot id: A0A1J0VD85
names: Similarity
messages: Belongs to the TrpC family.

1897729:BOX17 RS11940
gene id: 1897729:BOX17_RS11940
uniprot id: A0A1J0VHS9
names: Similarity
messages: Belongs to the GMC oxidoreductase family.

1897729:BOX17 RS05775
gene id: 1897729:BOX17_RS05775
uniprot id: A0A1J0VER6
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M20 family.
messages: Binds 2 Zn(2+) ions per subunit.

1897729:BOX17 RS11405
gene id: 1897729:BOX17_RS11405
uniprot id: A0A1J0VHJ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferrochelatase family.
messages: Catalyzes the ferrous insertion into protoporphyrin IX.
messages: Cytoplasm

1897729:BOX17 RS03335
gene id: 1897729:BOX17_RS03335
uniprot id: A0A1J0VDL0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.
messages: Heterodimer composed of CysD, the smaller subunit, and CysN.
messages: With CysD forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway. APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD.

1897729:BOX17 RS14550
gene id: 1897729:BOX17_RS14550
uniprot id: A0A1J0VJ31
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1897729:BOX17 RS11560
gene id: 1897729:BOX17_RS11560
uniprot id: A0A1J0VHJ8
names: Function
names: Similarity
messages: Belongs to the DHNA family.
messages: Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin.

1897729:BOX17 RS06035
gene id: 1897729:BOX17_RS06035
uniprot id: A0A1J0VES1
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1897729:BOX17 RS09530
gene id: 1897729:BOX17_RS09530
uniprot id: A0A1J0VGM3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.

1897729:BOX17 RS06125
gene id: 1897729:BOX17_RS06125
uniprot id: A0A1J0VEU0
names: Subcellular Location Annotation
messages: Membrane

1897729:BOX17 RS08535
gene id: 1897729:BOX17_RS08535
uniprot id: A0A1J0VG36
names: Function
names: Similarity
messages: Belongs to the methylglyoxal synthase family.
messages: Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate.

1897729:BOX17 RS02050
gene id: 1897729:BOX17_RS02050
uniprot id: A0A1J0VCT0
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1897729:BOX17 RS01190
gene id: 1897729:BOX17_RS01190
uniprot id: A0A1J0VCD1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RfaH family.
messages: Enhances distal genes transcription elongation in a specialized subset of operons that encode extracytoplasmic components.
messages: Interacts with both the nontemplate DNA and the RNA polymerase (RNAP).

1897729:BOX17 RS07045
gene id: 1897729:BOX17_RS07045
uniprot id: A0A1J0VFD3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Nitrate/nitrite porter (TC 2.A.1.8) family.
messages: Membrane

1897729:BOX17 RS03590
gene id: 1897729:BOX17_RS03590
uniprot id: A0A1J0VDJ9
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG).

1897729:BOX17 RS04720
gene id: 1897729:BOX17_RS04720
uniprot id: A0A1J0VE65
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)- to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Homodimer.

1897729:BOX17 RS14625
gene id: 1897729:BOX17_RS14625
uniprot id: A0A1J0VJ35
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

1897729:BOX17 RS09065
gene id: 1897729:BOX17_RS09065
uniprot id: A0A1J0VGE3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

1897729:BOX17 RS00220
gene id: 1897729:BOX17_RS00220
uniprot id: A0A1J0VBU4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA gyrase inhibitor YacG family.
messages: Binds 1 zinc ion.
messages: Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase.
messages: Interacts with GyrB.

1897729:BOX17 RS01545
gene id: 1897729:BOX17_RS01545
uniprot id: A0A1J0VCJ7
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

1897729:BOX17 RS05875
gene id: 1897729:BOX17_RS05875
uniprot id: A0A1J0VET3
names: Similarity
messages: Belongs to the bacterial ring-hydroxylating dioxygenase beta subunit family.

1897729:BOX17 RS14240
gene id: 1897729:BOX17_RS14240
uniprot id: A0A1J0VIY8
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1897729:BOX17 RS09435
gene id: 1897729:BOX17_RS09435
uniprot id: A0A1J0VGJ3
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

1897729:BOX17 RS10150
gene id: 1897729:BOX17_RS10150
uniprot id: A0A1J0VGX2
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Homooctamer.

1897729:BOX17 RS09515
gene id: 1897729:BOX17_RS09515
uniprot id: A0A1J0VGI9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamD family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

1897729:BOX17 RS06780
gene id: 1897729:BOX17_RS06780
uniprot id: A0A1J0VFB1
names: Subcellular Location Annotation
messages: Membrane

1897729:BOX17 RS14260
gene id: 1897729:BOX17_RS14260
uniprot id: A0A1J0VIX1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccD/PCCB family.
messages: Binds 1 zinc ion per subunit.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

1897729:BOX17 RS14755
gene id: 1897729:BOX17_RS14755
uniprot id: A0A1J0VJ79
names: Function
names: Similarity
messages: Belongs to the PurU family.
messages: Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).

1897729:BOX17 RS03415
gene id: 1897729:BOX17_RS03415
uniprot id: A0A1J0VDI7
names: Function
names: Similarity
messages: Belongs to the dihydrofolate reductase family.
messages: Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.

1897729:BOX17 RS00345
gene id: 1897729:BOX17_RS00345
uniprot id: A0A1J0VBY2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.

1897729:BOX17 RS13360
gene id: 1897729:BOX17_RS13360
uniprot id: A0A1J0VIH2
names: Subcellular Location Annotation
messages: Membrane

1897729:BOX17 RS06485
gene id: 1897729:BOX17_RS06485
uniprot id: A0A1J0VF39
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family.
messages: Binds 1 Mg(2+) ion per subunit. Can also utilize other divalent metal cations, such as Ca(2+), Mn(2+) and Co(2+).
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
messages: Homodimer.

1897729:BOX17 RS06145
gene id: 1897729:BOX17_RS06145
uniprot id: A0A1J0VEV6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1897729:BOX17 RS14560
gene id: 1897729:BOX17_RS14560
uniprot id: A0A1J0VJ44
names: Similarity
messages: Belongs to the phosphate/phosphite/phosphonate binding protein family.

1897729:BOX17 RS01560
gene id: 1897729:BOX17_RS01560
uniprot id: A0A1J0VK74
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

1897729:BOX17 RS11920
gene id: 1897729:BOX17_RS11920
uniprot id: A0A1J0VHR1
names: Similarity
messages: Belongs to the glutamate synthase family.

1897729:BOX17 RS09765
gene id: 1897729:BOX17_RS09765
uniprot id: A0A1J0VGN1
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

1897729:BOX17 RS11090
gene id: 1897729:BOX17_RS11090
uniprot id: A0A1J0VHC0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

1897729:BOX17 RS14390
gene id: 1897729:BOX17_RS14390
uniprot id: A0A1J0VJ12
names: Similarity
messages: Belongs to the UPF0065 (bug) family.

1897729:BOX17 RS07135
gene id: 1897729:BOX17_RS07135
uniprot id: A0A1J0VFF3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

1897729:BOX17 RS07320
gene id: 1897729:BOX17_RS07320
uniprot id: A0A1J0VFI1
names: Subcellular Location Annotation
messages: Membrane

1897729:BOX17 RS14710
gene id: 1897729:BOX17_RS14710
uniprot id: A0A1J0VJ75
names: Similarity
names: Subunit
messages: Belongs to the MoaE family.
messages: Heterotetramer of 2 MoaD subunits and 2 MoaE subunits. Also stable as homodimer. The enzyme changes between these two forms during catalysis.

1897729:BOX17 RS14190
gene id: 1897729:BOX17_RS14190
uniprot id: A0A1J0VIW4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptE lipoprotein family.
messages: Cell outer membrane
messages: Component of the lipopolysaccharide transport and assembly complex. Interacts with LptD.
messages: Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane.

1897729:BOX17 RS11105
gene id: 1897729:BOX17_RS11105
uniprot id: A0A1J0VHB8
names: Similarity
messages: Belongs to the SAICAR synthetase family.

1897729:BOX17 RS10095
gene id: 1897729:BOX17_RS10095
uniprot id: A0A1J0VGT6
names: Subcellular Location Annotation
messages: Cytoplasm

1897729:BOX17 RS03050
gene id: 1897729:BOX17_RS03050
uniprot id: A0A1J0VDD0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the heat shock protein 90 family.
messages: Cytoplasm
messages: Homodimer.
messages: Molecular chaperone. Has ATPase activity.

1897729:BOX17 RS02145
gene id: 1897729:BOX17_RS02145
uniprot id: A0A1J0VCV9
names: Similarity
messages: Belongs to the glutamine synthetase family.

1897729:BOX17 RS05380
gene id: 1897729:BOX17_RS05380
uniprot id: A0A1J0VEL5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

1897729:BOX17 RS09090
gene id: 1897729:BOX17_RS09090
uniprot id: A0A1J0VGD3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

1897729:BOX17 RS07630
gene id: 1897729:BOX17_RS07630
uniprot id: A0A1J0VFK5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. UvrD subfamily.
messages: Homodimer.
messages: Rep helicase is a single-stranded DNA-dependent ATPase involved in DNA replication; it can initiate unwinding at a nick in the DNA. It binds to the single-stranded DNA and acts in a progressive fashion along the DNA in the 3' to 5' direction.

1897729:BOX17 RS00750
gene id: 1897729:BOX17_RS00750
uniprot id: A0A1J0VC59
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1897729:BOX17 RS11110
gene id: 1897729:BOX17_RS11110
uniprot id: A0A1J0VHE3
names: Similarity
messages: Belongs to the tRNA methyltransferase O family.

1897729:BOX17 RS08175
gene id: 1897729:BOX17_RS08175
uniprot id: A0A1J0VFX7
names: Similarity
messages: Belongs to the prokaryotic GSH synthase family.

1897729:BOX17 RS09050
gene id: 1897729:BOX17_RS09050
uniprot id: A0A1J0VGD1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

1897729:BOX17 RS03205
gene id: 1897729:BOX17_RS03205
uniprot id: A0A1J0VDD8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

1897729:BOX17 RS12165
gene id: 1897729:BOX17_RS12165
uniprot id: A0A1J0VHW5
names: Function
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.

1897729:BOX17 RS15710
gene id: 1897729:BOX17_RS15710
uniprot id: A0A1J0VJM9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1897729:BOX17 RS15895
gene id: 1897729:BOX17_RS15895
uniprot id: A0A1J0VJT4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1897729:BOX17 RS10830
gene id: 1897729:BOX17_RS10830
uniprot id: A0A1J0VH70
names: Subcellular Location Annotation
messages: Membrane

1897729:BOX17 RS07190
gene id: 1897729:BOX17_RS07190
uniprot id: A0A1J0VFF5
names: Similarity
names: Subunit
messages: Belongs to the Ahb/Nir family.
messages: Probably forms a complex composed of NirD, NirL, NirG and NirH. All proteins are required for the total conversion of siroheme to didecarboxysiroheme.

1897729:BOX17 RS06975
gene id: 1897729:BOX17_RS06975
uniprot id: A0A1J0VF92
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1897729:BOX17 RS05890
gene id: 1897729:BOX17_RS05890
uniprot id: A0A1J0VEP9
names: Similarity
names: Subunit
messages: Belongs to the muconolactone Delta-isomerase family.
messages: Homodecamer.

1897729:BOX17 RS15145
gene id: 1897729:BOX17_RS15145
uniprot id: A0A1J0VJE7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

1897729:BOX17 RS00425
gene id: 1897729:BOX17_RS00425
uniprot id: A0A1J0VC09
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm

1897729:BOX17 RS08540
gene id: 1897729:BOX17_RS08540
uniprot id: A0A1J0VG35
names: Similarity
messages: Belongs to the pyruvate kinase family.

1897729:BOX17 RS10315
gene id: 1897729:BOX17_RS10315
uniprot id: A0A1J0VH07
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1897729:BOX17 RS09145
gene id: 1897729:BOX17_RS09145
uniprot id: A0A1J0VGD7
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

1897729:BOX17 RS02640
gene id: 1897729:BOX17_RS02640
uniprot id: A0A1J0VD40
names: Similarity
messages: Belongs to the ribose-phosphate pyrophosphokinase family.

1897729:BOX17 RS02425
gene id: 1897729:BOX17_RS02425
uniprot id: A0A1J0VD15
names: Similarity
messages: Belongs to the UPF0057 (PMP3) family.

1897729:BOX17 RS07745
gene id: 1897729:BOX17_RS07745
uniprot id: A0A1J0VFQ0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

1897729:BOX17 RS10085
gene id: 1897729:BOX17_RS10085
uniprot id: A0A1J0VGW5
names: Function
names: Similarity
messages: Belongs to the LpxB family.
messages: Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

1897729:BOX17 RS06335
gene id: 1897729:BOX17_RS06335
uniprot id: A0A1J0VEZ2
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

1897729:BOX17 RS09625
gene id: 1897729:BOX17_RS09625
uniprot id: A0A1J0VGL0
names: Similarity
messages: Belongs to the LOG family.

1897729:BOX17 RS04420
gene id: 1897729:BOX17_RS04420
uniprot id: A0A1J0VE12
names: Similarity
messages: Belongs to the hyi family.

1897729:BOX17 RS08580
gene id: 1897729:BOX17_RS08580
uniprot id: A0A1J0VG46
names: Similarity
messages: Belongs to the ribosome association toxin RatA family.

1897729:BOX17 RS01215
gene id: 1897729:BOX17_RS01215
uniprot id: A0A1J0VCG9
names: Function
names: Similarity
messages: Belongs to the ketopantoate reductase family.
messages: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.

1897729:BOX17 RS10090
gene id: 1897729:BOX17_RS10090
uniprot id: A0A1J0VGU0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

1897729:BOX17 RS05415
gene id: 1897729:BOX17_RS05415
uniprot id: A0A1J0VEI5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

1897729:BOX17 RS11840
gene id: 1897729:BOX17_RS11840
uniprot id: A0A1J0VHP6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1897729:BOX17 RS09105
gene id: 1897729:BOX17_RS09105
uniprot id: A0A1J0VGC7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

1897729:BOX17 RS09790
gene id: 1897729:BOX17_RS09790
uniprot id: A0A1J0VKI4
names: Similarity
messages: Belongs to the RecJ family.

1897729:BOX17 RS01765
gene id: 1897729:BOX17_RS01765
uniprot id: A0A1J0VCN6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1897729:BOX17 RS10435
gene id: 1897729:BOX17_RS10435
uniprot id: A0A1J0VH09
names: Function
names: Similarity
messages: Belongs to the CcmH/CycL/Ccl2/NrfF family.
messages: Possible subunit of a heme lyase.

1897729:BOX17 RS09525
gene id: 1897729:BOX17_RS09525
uniprot id: A0A1J0VGK8
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

1897729:BOX17 RS01225
gene id: 1897729:BOX17_RS01225
uniprot id: A0A1J0VCF1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PEPCase type 1 family.
messages: Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.
messages: Homotetramer.

1897729:BOX17 RS09460
gene id: 1897729:BOX17_RS09460
uniprot id: A0A1J0VGI3
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

1897729:BOX17 RS05055
gene id: 1897729:BOX17_RS05055
uniprot id: A0A1J0VEB8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

1897729:BOX17 RS13495
gene id: 1897729:BOX17_RS13495
uniprot id: A0A1J0VIK1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase D family.
messages: Cytoplasm
messages: Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides.

1897729:BOX17 RS01745
gene id: 1897729:BOX17_RS01745
uniprot id: A0A1J0VCN1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).

1897729:BOX17 RS14040
gene id: 1897729:BOX17_RS14040
uniprot id: A0A1J0VIT1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RlpA family.
messages: Cell membrane
messages: Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides.

1897729:BOX17 RS09950
gene id: 1897729:BOX17_RS09950
uniprot id: A0A1J0VGU2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsuA/YedE (TC 9.B.102) family.
messages: Cell inner membrane
messages: Membrane

1897729:BOX17 RS10410
gene id: 1897729:BOX17_RS10410
uniprot id: A0A1J0VH23
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmC/CycZ/HelC family.
messages: Cell inner membrane
messages: Membrane
messages: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.

1897729:BOX17 RS16460
gene id: 1897729:BOX17_RS16460
uniprot id: A0A1J0VK34
names: Similarity
messages: Belongs to the UPF0225 family.

1897729:BOX17 RS02800
gene id: 1897729:BOX17_RS02800
uniprot id: A0A1J0VD69
names: Similarity
messages: Belongs to the PrpF family.

1897729:BOX17 RS14020
gene id: 1897729:BOX17_RS14020
uniprot id: A0A1J0VIT2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

1897729:BOX17 RS06065
gene id: 1897729:BOX17_RS06065
uniprot id: A0A1J0VEW4
names: Function
names: Similarity
messages: Belongs to the GlnE family.
messages: Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell.

1897729:BOX17 RS11415
gene id: 1897729:BOX17_RS11415
uniprot id: A0A1J0VHI3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit F family.
messages: Cell membrane
messages: Membrane

1897729:BOX17 RS07225
gene id: 1897729:BOX17_RS07225
uniprot id: A0A1J0VFG9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase U32 family. UbiV subfamily.
messages: Forms an heterodimer with UbiU.
messages: Required for O(2)-independent ubiquinone (coenzyme Q) biosynthesis. Together with UbiU, is essential for the C6-hydroxylation reaction in the oxygen-independent ubiquinone biosynthesis pathway.

1897729:BOX17 RS01690
gene id: 1897729:BOX17_RS01690
uniprot id: A0A1J0VCM5
names: Similarity
messages: Belongs to the Nudix hydrolase family.

1897729:BOX17 RS09510
gene id: 1897729:BOX17_RS09510
uniprot id: A0A1J0VGJ1
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
messages: In the C-terminal section; belongs to the NAD synthetase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1897729:BOX17 RS06270
gene id: 1897729:BOX17_RS06270
uniprot id: A0A1J0VEY3
names: Function
names: Similarity
messages: Belongs to the Fe(2+)-trafficking protein family.
messages: Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes.

1897729:BOX17 RS14505
gene id: 1897729:BOX17_RS14505
uniprot id: A0A1J0VJ34
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dCTP deaminase family.
messages: Catalyzes the deamination of dCTP to dUTP.
messages: Homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1897729:BOX17 RS16275
gene id: 1897729:BOX17_RS16275
uniprot id: A0A1J0VK02
names: Similarity
messages: Belongs to the pirin family.

1897729:BOX17 RS15445
gene id: 1897729:BOX17_RS15445
uniprot id: A0A1J0VJK1
names: Similarity
messages: Belongs to the DsrF/TusC family.

1897729:BOX17 RS08480
gene id: 1897729:BOX17_RS08480
uniprot id: A0A1J0VG22
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

1897729:BOX17 RS15905
gene id: 1897729:BOX17_RS15905
uniprot id: A0A1J0VJS5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I fumarase family.
messages: Catalyzes the reversible hydration of fumarate to (S)-malate.
messages: Homodimer.

1897729:BOX17 RS02315
gene id: 1897729:BOX17_RS02315
uniprot id: A0A1J0VCZ5
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1897729:BOX17 RS06955
gene id: 1897729:BOX17_RS06955
uniprot id: A0A1J0VF91
names: Similarity
messages: Belongs to the creatininase superfamily.

1897729:BOX17 RS03915
gene id: 1897729:BOX17_RS03915
uniprot id: A0A1J0VDQ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial glucokinase family.
messages: Cytoplasm

1897729:BOX17 RS08235
gene id: 1897729:BOX17_RS08235
uniprot id: A0A1J0VFW3
names: Domain
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cell inner membrane
messages: Homodimer.
messages: Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB/RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host.
messages: The transmembrane domain is a dimerization domain.

1897729:BOX17 RS16100
gene id: 1897729:BOX17_RS16100
uniprot id: A0A1J0VJX7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1897729:BOX17 RS05925
gene id: 1897729:BOX17_RS05925
uniprot id: A0A1J0VER9
names: Similarity
messages: Belongs to the DODA-type extradiol aromatic ring-opening dioxygenase family.

1897729:BOX17 RS05565
gene id: 1897729:BOX17_RS05565
uniprot id: A0A1J0VEM0
names: Function
names: Similarity
messages: Belongs to the peroxiredoxin family. Prx5 subfamily.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

1897729:BOX17 RS14275
gene id: 1897729:BOX17_RS14275
uniprot id: A0A1J0VIY2
names: Subcellular Location Annotation
messages: Membrane

1897729:BOX17 RS02705
gene id: 1897729:BOX17_RS02705
uniprot id: A0A1J0VD64
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal stress protein A family.
messages: Cytoplasm

1897729:BOX17 RS05585
gene id: 1897729:BOX17_RS05585
uniprot id: A0A1J0VEL3
names: Function
names: Similarity
messages: Belongs to the bacterioferritin family.
messages: Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex.

1897729:BOX17 RS10180
gene id: 1897729:BOX17_RS10180
uniprot id: A0A1J0VGV4
names: Function
names: Similarity
messages: Belongs to the ABC1 family. UbiB subfamily.
messages: Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis.

1897729:BOX17 RS00540
gene id: 1897729:BOX17_RS00540
uniprot id: A0A1J0VC23
names: Function
names: Similarity
names: Subunit
messages: Belongs to the OMP decarboxylase family. Type 1 subfamily.
messages: Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
messages: Homodimer.

1897729:BOX17 RS09890
gene id: 1897729:BOX17_RS09890
uniprot id: A0A1J0VGR5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm

1897729:BOX17 RS02900
gene id: 1897729:BOX17_RS02900
uniprot id: A0A1J0VK92
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate synthase component I family.
messages: Heterotetramer consisting of two non-identical subunits: a beta subunit (TrpG) and a large alpha subunit (TrpE).
messages: Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia.

1897729:BOX17 RS01740
gene id: 1897729:BOX17_RS01740
uniprot id: A0A1J0VK72
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

1897729:BOX17 RS15435
gene id: 1897729:BOX17_RS15435
uniprot id: A0A1J0VJK0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

1897729:BOX17 RS15775
gene id: 1897729:BOX17_RS15775
uniprot id: A0A1J0VJP4
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

1897729:BOX17 RS03375
gene id: 1897729:BOX17_RS03375
uniprot id: A0A1J0VDH6
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. CmoM family.
messages: Catalyzes the methylation of 5-carboxymethoxyuridine (cmo5U) to form 5-methoxycarbonylmethoxyuridine (mcmo5U) at position 34 in tRNAs.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1897729:BOX17 RS05005
gene id: 1897729:BOX17_RS05005
uniprot id: A0A1J0VEF3
names: Function
names: Similarity
names: Subunit
messages: A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild-type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity.
messages: Belongs to the RecC family.
messages: Heterotrimer of RecB, RecC and RecD. All subunits contribute to DNA-binding.

1897729:BOX17 RS10415
gene id: 1897729:BOX17_RS10415
uniprot id: A0A1J0VKM0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmD/CycX/HelD family.
messages: Cell inner membrane
messages: Membrane
messages: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.

1897729:BOX17 RS08820
gene id: 1897729:BOX17_RS08820
uniprot id: A0A1J0VG66
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1897729:BOX17 RS02075
gene id: 1897729:BOX17_RS02075
uniprot id: A0A1J0VCU5
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

1897729:BOX17 RS12915
gene id: 1897729:BOX17_RS12915
uniprot id: A0A1J0VI96
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1897729:BOX17 RS09865
gene id: 1897729:BOX17_RS09865
uniprot id: A0A1J0VGP7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. SRP is a ribonucleoprotein composed of Ffh and a 4.5S RNA molecule.

1897729:BOX17 RS11620
gene id: 1897729:BOX17_RS11620
uniprot id: A0A1J0VHM8
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1897729:BOX17 RS00080
gene id: 1897729:BOX17_RS00080
uniprot id: A0A1J0VBV3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the QueC family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).

1897729:BOX17 RS12220
gene id: 1897729:BOX17_RS12220
uniprot id: A0A1J0VHX0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1897729:BOX17 RS12820
gene id: 1897729:BOX17_RS12820
uniprot id: A0A1J0VI83
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

1897729:BOX17 RS16055
gene id: 1897729:BOX17_RS16055
uniprot id: A0A1J0VJW7
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit A family.

1897729:BOX17 RS12985
gene id: 1897729:BOX17_RS12985
uniprot id: A0A1J0VID5
names: Function
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.
messages: Provides the (R)-glutamate required for cell wall biosynthesis.

1897729:BOX17 RS05530
gene id: 1897729:BOX17_RS05530
uniprot id: A0A1J0VEL9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TrkH potassium transport family.
messages: Cell inner membrane
messages: Membrane

1897729:BOX17 RS14045
gene id: 1897729:BOX17_RS14045
uniprot id: A0A1J0VIU9
names: Function
names: Similarity
messages: Belongs to the peptidase S11 family.
messages: Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors.

1897729:BOX17 RS06350
gene id: 1897729:BOX17_RS06350
uniprot id: A0A1J0VEZ9
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

1897729:BOX17 RS08695
gene id: 1897729:BOX17_RS08695
uniprot id: A0A1J0VG45
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1897729:BOX17 RS00760
gene id: 1897729:BOX17_RS00760
uniprot id: A0A1J0VC60
names: Similarity
messages: Belongs to the HMG-CoA lyase family.

1897729:BOX17 RS14410
gene id: 1897729:BOX17_RS14410
uniprot id: A0A1J0VJ16
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1897729:BOX17 RS10305
gene id: 1897729:BOX17_RS10305
uniprot id: A0A1J0VGX9
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

1897729:BOX17 RS16130
gene id: 1897729:BOX17_RS16130
uniprot id: A0A1J0VJY1
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1897729:BOX17 RS11545
gene id: 1897729:BOX17_RS11545
uniprot id: A0A1J0VHK5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GlpE family.
messages: Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide.
messages: Cytoplasm

1897729:BOX17 RS08760
gene id: 1897729:BOX17_RS08760
uniprot id: A0A1J0VG82
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

1897729:BOX17 RS13715
gene id: 1897729:BOX17_RS13715
uniprot id: A0A1J0VIP0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LamB/PxpA family.
messages: Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.
messages: Forms a complex composed of PxpA, PxpB and PxpC.

1897729:BOX17 RS04390
gene id: 1897729:BOX17_RS04390
uniprot id: A0A1J0VE03
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane.

1897729:BOX17 RS13000
gene id: 1897729:BOX17_RS13000
uniprot id: A0A1J0VIB7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

1897729:BOX17 RS15400
gene id: 1897729:BOX17_RS15400
uniprot id: A0A1J0VJJ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily.
messages: Cell inner membrane
messages: Involved in the import of queuosine (Q) precursors, required for Q precursor salvage.

1897729:BOX17 RS15960
gene id: 1897729:BOX17_RS15960
uniprot id: A0A1J0VJU6
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1897729:BOX17 RS10675
gene id: 1897729:BOX17_RS10675
uniprot id: A0A1J0VH69
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transglycosylase Slt family.
messages: Cell outer membrane
messages: In the C-terminal section; belongs to the transglycosylase Slt family.
messages: In the N-terminal section; belongs to the bacterial solute-binding protein 3 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella.
messages: The N-terminal domain does not have lytic activity and probably modulates enzymatic activity. The C-terminal domain is the catalytic active domain.

1897729:BOX17 RS15335
gene id: 1897729:BOX17_RS15335
uniprot id: A0A1J0VJF7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1897729:BOX17 RS11305
gene id: 1897729:BOX17_RS11305
uniprot id: A0A1J0VHF0
names: Similarity
messages: In the N-terminal section; belongs to the NADH:flavin oxidoreductase/NADH oxidase family.

1897729:BOX17 RS14210
gene id: 1897729:BOX17_RS14210
uniprot id: A0A1J0VIZ3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1897729:BOX17 RS01355
gene id: 1897729:BOX17_RS01355
uniprot id: A0A1J0VCG1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

1897729:BOX17 RS02555
gene id: 1897729:BOX17_RS02555
uniprot id: A0A1J0VD39
names: Similarity
messages: Belongs to the YjdM family.

1897729:BOX17 RS08260
gene id: 1897729:BOX17_RS08260
uniprot id: A0A1J0VFY5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the uroporphyrinogen decarboxylase family.
messages: Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1897729:BOX17 RS01185
gene id: 1897729:BOX17_RS01185
uniprot id: A0A1J0VCE5
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

1897729:BOX17 RS04830
gene id: 1897729:BOX17_RS04830
uniprot id: A0A1J0VE64
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family. T3SS ATPase subfamily.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

1897729:BOX17 RS14680
gene id: 1897729:BOX17_RS14680
uniprot id: A0A1J0VJ65
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

1897729:BOX17 RS09780
gene id: 1897729:BOX17_RS09780
uniprot id: A0A1J0VGR1
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

1897729:BOX17 RS02580
gene id: 1897729:BOX17_RS02580
uniprot id: A0A1J0VD25
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

1897729:BOX17 RS02175
gene id: 1897729:BOX17_RS02175
uniprot id: A0A1J0VCW6
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

1897729:BOX17 RS16340
gene id: 1897729:BOX17_RS16340
uniprot id: A0A1J0VJZ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1897729:BOX17 RS06135
gene id: 1897729:BOX17_RS06135
uniprot id: A0A1J0VEZ5
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

1897729:BOX17 RS08490
gene id: 1897729:BOX17_RS08490
uniprot id: A0A1J0VG27
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm
messages: In the N-terminal section; belongs to the lyase 1 family. Argininosuccinate lyase subfamily.

1897729:BOX17 RS03530
gene id: 1897729:BOX17_RS03530
uniprot id: A0A1J0VDP4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Cytoplasm
messages: Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1897729:BOX17 RS06235
gene id: 1897729:BOX17_RS06235
uniprot id: A0A1J0VEZ8
names: Similarity
messages: Belongs to the pseudomonas-type ThrB family.

1897729:BOX17 RS09100
gene id: 1897729:BOX17_RS09100
uniprot id: A0A1J0VGD0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

1897729:BOX17 RS13645
gene id: 1897729:BOX17_RS13645
uniprot id: A0A1J0VIN2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0718 family.
messages: Cell membrane
messages: Membrane

1897729:BOX17 RS12080
gene id: 1897729:BOX17_RS12080
uniprot id: A0A1J0VHU8
names: Similarity
messages: Belongs to the bacterial solute-binding protein 9 family.

1897729:BOX17 RS10885
gene id: 1897729:BOX17_RS10885
uniprot id: A0A1J0VHA3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MgtC/SapB family.
messages: Membrane

1897729:BOX17 RS14225
gene id: 1897729:BOX17_RS14225
uniprot id: A0A1J0VIY6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1897729:BOX17 RS03405
gene id: 1897729:BOX17_RS03405
uniprot id: A0A1J0VDG4
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

1897729:BOX17 RS03150
gene id: 1897729:BOX17_RS03150
uniprot id: A0A1J0VDC0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Cob(I)alamin adenosyltransferase family.
messages: Cytoplasm
messages: Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids.

1897729:BOX17 RS09155
gene id: 1897729:BOX17_RS09155
uniprot id: A0A1J0VGC6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

1897729:BOX17 RS01550
gene id: 1897729:BOX17_RS01550
uniprot id: A0A1J0VCN5
names: Function
names: Similarity
messages: Belongs to the transglycosylase MltG family.
messages: Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.

1897729:BOX17 RS14955
gene id: 1897729:BOX17_RS14955
uniprot id: A0A1J0VJ93
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial sugar transferase family.
messages: Membrane

1897729:BOX17 RS09135
gene id: 1897729:BOX17_RS09135
uniprot id: A0A1J0VGE7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

1897729:BOX17 RS11215
gene id: 1897729:BOX17_RS11215
uniprot id: A0A1J0VHE5
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TtcA family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is chelated by three Cys residues, the fourth Fe has a free coordination site that may bind a sulfur atom transferred from the persulfide of IscS.
messages: Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system.
messages: Cytoplasm
messages: Homodimer.
messages: The thiolation reaction likely consists of two steps: a first activation step by ATP to form an adenylated intermediate of the target base of tRNA, and a second nucleophilic substitution step of the sulfur (S) atom supplied by the hydrosulfide attached to the Fe-S cluster.

1897729:BOX17 RS07970
gene id: 1897729:BOX17_RS07970
uniprot id: A0A1J0VFR7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

1897729:BOX17 RS07840
gene id: 1897729:BOX17_RS07840
uniprot id: A0A1J0VFT9
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane
messages: Membrane

1897729:BOX17 RS13415
gene id: 1897729:BOX17_RS13415
uniprot id: A0A1J0VII4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

1897729:BOX17 RS16095
gene id: 1897729:BOX17_RS16095
uniprot id: A0A1J0VJV2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

1897729:BOX17 RS08445
gene id: 1897729:BOX17_RS08445
uniprot id: A0A1J0VG20
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbA subfamily.
messages: Periplasm

1897729:BOX17 RS02625
gene id: 1897729:BOX17_RS02625
uniprot id: A0A1J0VD41
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

1897729:BOX17 RS01245
gene id: 1897729:BOX17_RS01245
uniprot id: A0A1J0VCC4
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

1897729:BOX17 RS09185
gene id: 1897729:BOX17_RS09185
uniprot id: A0A1J0VGE6
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

1897729:BOX17 RS09925
gene id: 1897729:BOX17_RS09925
uniprot id: A0A1J0VGS0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FPG family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
messages: Monomer.

1897729:BOX17 RS08140
gene id: 1897729:BOX17_RS08140
uniprot id: A0A1J0VFU8
names: Similarity
messages: Belongs to the peptidase S41A family.

1897729:BOX17 RS10155
gene id: 1897729:BOX17_RS10155
uniprot id: A0A1J0VGX5
names: Function
names: Similarity
messages: Belongs to the peptidase C56 family.
messages: Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate.

1897729:BOX17 RS13865
gene id: 1897729:BOX17_RS13865
uniprot id: A0A1J0VIS3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dethiobiotin synthetase family.
messages: Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1897729:BOX17 RS00320
gene id: 1897729:BOX17_RS00320
uniprot id: A0A1J0VBY5
names: Subcellular Location Annotation
messages: Membrane

1897729:BOX17 RS08790
gene id: 1897729:BOX17_RS08790
uniprot id: A0A1J0VG92
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DksA family.
messages: Cytoplasm
messages: Interacts directly with the RNA polymerase.
messages: Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters. Also required for regulation of fis expression.

1897729:BOX17 RS01695
gene id: 1897729:BOX17_RS01695
uniprot id: A0A1J0VCN7
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArgJ family.
messages: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.
messages: Cytoplasm
messages: Heterotetramer of two alpha and two beta chains.
messages: Some bacteria possess a monofunctional ArgJ, i.e., capable of catalyzing only the fifth step of the arginine biosynthetic pathway.

1897729:BOX17 RS05410
gene id: 1897729:BOX17_RS05410
uniprot id: A0A1J0VEF9
names: Similarity
messages: Belongs to the HesB/IscA family.

1897729:BOX17 RS13435
gene id: 1897729:BOX17_RS13435
uniprot id: A0A1J0VIH0
names: Similarity
messages: Belongs to the peptidase M20A family.

1897729:BOX17 RS01880
gene id: 1897729:BOX17_RS01880
uniprot id: A0A1J0VCT1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Lacks the C-terminal regulatory region which is replaced by HisZ.

1897729:BOX17 RS10265
gene id: 1897729:BOX17_RS10265
uniprot id: A0A1J0VGX1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial secretin family.
messages: Cell outer membrane
messages: Membrane

1897729:BOX17 RS14605
gene id: 1897729:BOX17_RS14605
uniprot id: A0A1J0VJ32
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1897729:BOX17 RS12130
gene id: 1897729:BOX17_RS12130
uniprot id: A0A1J0VHW9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endonuclease V family.
messages: Cytoplasm
messages: DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA.

1897729:BOX17 RS01240
gene id: 1897729:BOX17_RS01240
uniprot id: A0A1J0VCG3
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. RlmD subfamily.
messages: Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA.

1897729:BOX17 RS05920
gene id: 1897729:BOX17_RS05920
uniprot id: A0A1J0VKD6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DoxX family.
messages: Membrane

1897729:BOX17 RS01755
gene id: 1897729:BOX17_RS01755
uniprot id: A0A1J0VCQ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

1897729:BOX17 RS08250
gene id: 1897729:BOX17_RS08250
uniprot id: A0A1J0VFY2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0073 (Hly-III) family.
messages: Membrane

1897729:BOX17 RS09200
gene id: 1897729:BOX17_RS09200
uniprot id: A0A1J0VGD5
names: Function
names: Subunit
messages: Homotetramer.
messages: Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.

1897729:BOX17 RS10165
gene id: 1897729:BOX17_RS10165
uniprot id: A0A1J0VGW2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatB family.
messages: Cell membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

1897729:BOX17 RS10395
gene id: 1897729:BOX17_RS10395
uniprot id: A0A1J0VH22
names: Similarity
messages: Belongs to the peptidase S24 family.

1897729:BOX17 RS02915
gene id: 1897729:BOX17_RS02915
uniprot id: A0A1J0VD88
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Cell inner membrane
messages: Homoheptamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mechanosensitive channel that participates in the regulation of osmotic pressure changes within the cell, opening in response to stretch forces in the membrane lipid bilayer, without the need for other proteins. Contributes to normal resistance to hypoosmotic shock. Forms an ion channel of 1.0 nanosiemens conductance with a slight preference for anions.
messages: Membrane

1897729:BOX17 RS01340
gene id: 1897729:BOX17_RS01340
uniprot id: A0A1J0VCJ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane
messages: Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins.

1897729:BOX17 RS07640
gene id: 1897729:BOX17_RS07640
uniprot id: A0A1J0VFL5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.

1897729:BOX17 RS15625
gene id: 1897729:BOX17_RS15625
uniprot id: A0A1J0VJM7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PRA-CH family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.
messages: Cytoplasm
messages: Homodimer.

1897729:BOX17 RS03830
gene id: 1897729:BOX17_RS03830
uniprot id: A0A1J0VDQ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.
messages: Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins.
messages: Cytoplasm

1897729:BOX17 RS16035
gene id: 1897729:BOX17_RS16035
uniprot id: A0A1J0VJW3
names: Similarity
messages: Belongs to the phosphate acetyltransferase and butyryltransferase family.

1897729:BOX17 RS03580
gene id: 1897729:BOX17_RS03580
uniprot id: A0A1J0VDQ4
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

1897729:BOX17 RS11070
gene id: 1897729:BOX17_RS11070
uniprot id: A0A1J0VHD5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48 family. BepA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Functions as both a chaperone and a metalloprotease. Maintains the integrity of the outer membrane by promoting either the assembly or the elimination of outer membrane proteins, depending on their folding state.
messages: Periplasm

1897729:BOX17 RS07590
gene id: 1897729:BOX17_RS07590
uniprot id: A0A1J0VFN3
names: Similarity
messages: Belongs to the asparaginase 1 family.

1897729:BOX17 RS10500
gene id: 1897729:BOX17_RS10500
uniprot id: A0A1J0VH13
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Catalyzes the last two steps in the biosynthesis of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the DAO family.
messages: In the N-terminal section; belongs to the methyltransferase superfamily. tRNA (mnm(5)s(2)U34)-methyltransferase family.

1897729:BOX17 RS08595
gene id: 1897729:BOX17_RS08595
uniprot id: A0A1J0VG68
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Fur family.
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.

1897729:BOX17 RS03805
gene id: 1897729:BOX17_RS03805
uniprot id: A0A1J0VDN4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LpxL/LpxM/LpxP family.
messages: Catalyzes the transfer of an acyl chain from an acyl-[acyl-carrier-protein] (ACP) to a Kdo(2)-lipid IV(A) to form a Kdo(2)-(acyl)-lipid IV(A).
messages: Cell inner membrane

1897729:BOX17 RS00795
gene id: 1897729:BOX17_RS00795
uniprot id: A0A1J0VC62
names: Caution
names: Cofactor
names: Similarity
messages: Belongs to the WrbA family.
messages: Binds 1 FMN per monomer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1897729:BOX17 RS01530
gene id: 1897729:BOX17_RS01530
uniprot id: A0A1J0VCJ5
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. TatD-type hydrolase family.

1897729:BOX17 RS11185
gene id: 1897729:BOX17_RS11185
uniprot id: A0A1J0VHD3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1897729:BOX17 RS01500
gene id: 1897729:BOX17_RS01500
uniprot id: A0A1J0VCI9
names: Cofactor
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.
messages: Binds 1 FAD per dimer.

1897729:BOX17 RS07010
gene id: 1897729:BOX17_RS07010
uniprot id: A0A1J0VF99
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

1897729:BOX17 RS08205
gene id: 1897729:BOX17_RS08205
uniprot id: A0A1J0VFX9
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1897729:BOX17 RS01855
gene id: 1897729:BOX17_RS01855
uniprot id: A0A1J0VCU2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AFG1 ATPase family. ZapE subfamily.
messages: Cytoplasm
messages: Interacts with FtsZ.
messages: Reduces the stability of FtsZ polymers in the presence of ATP.

1897729:BOX17 RS07435
gene id: 1897729:BOX17_RS07435
uniprot id: A0A1J0VFH3
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.

1897729:BOX17 RS06200
gene id: 1897729:BOX17_RS06200
uniprot id: A0A1J0VEY6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

1897729:BOX17 RS07665
gene id: 1897729:BOX17_RS07665
uniprot id: A0A1J0VFL6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

1897729:BOX17 RS08130
gene id: 1897729:BOX17_RS08130
uniprot id: A0A1J0VFZ5
names: Similarity
messages: Belongs to the UbiH/COQ6 family.

1897729:BOX17 RS04825
gene id: 1897729:BOX17_RS04825
uniprot id: A0A1J0VEC3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

1897729:BOX17 RS02830
gene id: 1897729:BOX17_RS02830
uniprot id: A0A1J0VD75
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAPS reductase family. CysH subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of sulfite from adenosine 5'-phosphosulfate (APS) using thioredoxin as an electron donor.
messages: Cytoplasm

1897729:BOX17 RS14490
gene id: 1897729:BOX17_RS14490
uniprot id: A0A1J0VJ11
names: Similarity
messages: Belongs to the prokaryotic/mitochondrial release factor family.

1897729:BOX17 RS12090
gene id: 1897729:BOX17_RS12090
uniprot id: A0A1J0VHV6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1897729:BOX17 RS12705
gene id: 1897729:BOX17_RS12705
uniprot id: A0A1J0VI57
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.

1897729:BOX17 RS01110
gene id: 1897729:BOX17_RS01110
uniprot id: A0A1J0VCD9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YejK family.
messages: nucleoid

1897729:BOX17 RS06170
gene id: 1897729:BOX17_RS06170
uniprot id: A0A1J0VEW9
names: Similarity
messages: Belongs to the Dps family.

1897729:BOX17 RS07945
gene id: 1897729:BOX17_RS07945
uniprot id: A0A1J0VFT0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HemJ family.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.
messages: Catalyzes the oxidation of protoporphyrinogen IX to protoporphyrin IX.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

1897729:BOX17 RS02085
gene id: 1897729:BOX17_RS02085
uniprot id: A0A1J0VCX4
names: Similarity
messages: Belongs to the GcvT family.

1897729:BOX17 RS02235
gene id: 1897729:BOX17_RS02235
uniprot id: A0A1J0VCX5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

1897729:BOX17 RS13465
gene id: 1897729:BOX17_RS13465
uniprot id: A0A1J0VII5
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

1897729:BOX17 RS14105
gene id: 1897729:BOX17_RS14105
uniprot id: A0A1J0VIU5
names: Similarity
messages: Belongs to the GSP E family.

1897729:BOX17 RS00525
gene id: 1897729:BOX17_RS00525
uniprot id: A0A1J0VC55
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial histone-like protein family.
messages: Heterodimer of an alpha and a beta chain.
messages: This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.

1897729:BOX17 RS01125
gene id: 1897729:BOX17_RS01125
uniprot id: A0A1J0VCF7
names: Similarity
messages: Belongs to the thioredoxin family.

1897729:BOX17 RS11875
gene id: 1897729:BOX17_RS11875
uniprot id: A0A1J0VHS3
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG).

1897729:BOX17 RS11550
gene id: 1897729:BOX17_RS11550
uniprot id: A0A1J0VHK1
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

1897729:BOX17 RS06745
gene id: 1897729:BOX17_RS06745
uniprot id: A0A1J0VF53
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the inorganic carbon transporter (TC 9.A.2) DabA family.
messages: Cell membrane
messages: Forms a complex with DabB.
messages: Part of an energy-coupled inorganic carbon pump.

1897729:BOX17 RS05800
gene id: 1897729:BOX17_RS05800
uniprot id: A0A1J0VKF3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AzlC family.
messages: Membrane

1897729:BOX17 RS10715
gene id: 1897729:BOX17_RS10715
uniprot id: A0A1J0VH76
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.
messages: Cell membrane
messages: Heterodimer of a large and a small subunit.

1897729:BOX17 RS08030
gene id: 1897729:BOX17_RS08030
uniprot id: A0A1J0VFU5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gmhB family.
messages: Cytoplasm

1897729:BOX17 RS10340
gene id: 1897729:BOX17_RS10340
uniprot id: A0A1J0VH12
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

1897729:BOX17 RS00340
gene id: 1897729:BOX17_RS00340
uniprot id: A0A1J0VBZ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TVP38/TMEM64 family.
messages: Cell membrane
messages: Membrane

1897729:BOX17 RS09120
gene id: 1897729:BOX17_RS09120
uniprot id: A0A1J0VGC0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

1897729:BOX17 RS01000
gene id: 1897729:BOX17_RS01000
uniprot id: A0A1J0VCB2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CpxP/Spy family.
messages: Binds zinc. Could be an important component of the zinc-balancing mechanism.
messages: Periplasm

1897729:BOX17 RS05680
gene id: 1897729:BOX17_RS05680
uniprot id: A0A1J0VEL6
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

1897729:BOX17 RS02455
gene id: 1897729:BOX17_RS02455
uniprot id: A0A1J0VD13
names: Function
names: Similarity
messages: In the C-terminal section; belongs to the aldehyde dehydrogenase family.
messages: In the N-terminal section; belongs to the proline dehydrogenase family.
messages: Oxidizes proline to glutamate for use as a carbon and nitrogen source.

1897729:BOX17 RS12250
gene id: 1897729:BOX17_RS12250
uniprot id: A0A1J0VHZ1
names: Function
names: Similarity
messages: Belongs to the TenA family.
messages: Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway.

1897729:BOX17 RS01865
gene id: 1897729:BOX17_RS01865
uniprot id: A0A1J0VCR6
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

1897729:BOX17 RS02300
gene id: 1897729:BOX17_RS02300
uniprot id: A0A1J0VCY3
names: Function
names: Similarity
messages: Belongs to the GMC oxidoreductase family.
messages: Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate.

1897729:BOX17 RS07985
gene id: 1897729:BOX17_RS07985
uniprot id: A0A1J0VFT7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RlmJ family.
messages: Monomer.
messages: Specifically methylates the adenine in position 2030 of 23S rRNA.

1897729:BOX17 RS14925
gene id: 1897729:BOX17_RS14925
uniprot id: A0A1J0VJ85
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. GDP-mannose 4,6-dehydratase subfamily.
messages: Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6-deoxy-D-mannose.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1897729:BOX17 RS04500
gene id: 1897729:BOX17_RS04500
uniprot id: A0A1J0VE11
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lactate permease family.
messages: Cell inner membrane
messages: Membrane
messages: Uptake of L-lactate across the membrane. Can also transport D-lactate and glycolate.

1897729:BOX17 RS08115
gene id: 1897729:BOX17_RS08115
uniprot id: A0A1J0VFW1
names: Function
names: Similarity
names: Subunit
messages: Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division.
messages: Belongs to the ZapA family. Type 1 subfamily.
messages: Homodimer. Interacts with FtsZ.

1897729:BOX17 RS09130
gene id: 1897729:BOX17_RS09130
uniprot id: A0A1J0VGE0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

1897729:BOX17 RS09750
gene id: 1897729:BOX17_RS09750
uniprot id: A0A1J0VGP1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

1897729:BOX17 RS11635
gene id: 1897729:BOX17_RS11635
uniprot id: A0A1J0VHM0
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.

1897729:BOX17 RS09870
gene id: 1897729:BOX17_RS09870
uniprot id: A0A1J0VGS6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Homodimer. Forms a membrane-associated complex with FtsX.
messages: Part of the ABC transporter FtsEX involved in cellular division. Important for assembly or stability of the septal ring.

1897729:BOX17 RS14010
gene id: 1897729:BOX17_RS14010
uniprot id: A0A1J0VKR1
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

1897729:BOX17 RS13390
gene id: 1897729:BOX17_RS13390
uniprot id: A0A1J0VIJ4
names: Similarity
messages: Belongs to the TlyA family.

1897729:BOX17 RS00185
gene id: 1897729:BOX17_RS00185
uniprot id: A0A1J0VBW3
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1897729:BOX17 RS05615
gene id: 1897729:BOX17_RS05615
uniprot id: A0A1J0VEL8
names: Function
names: Similarity
messages: Acts on leucine, isoleucine and valine.
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

1897729:BOX17 RS03540
gene id: 1897729:BOX17_RS03540
uniprot id: A0A1J0VDJ0
names: Similarity
messages: Belongs to the HSP15 family.

1897729:BOX17 RS06455
gene id: 1897729:BOX17_RS06455
uniprot id: A0A1J0VF02
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.

1897729:BOX17 RS10925
gene id: 1897729:BOX17_RS10925
uniprot id: A0A1J0VHB1
names: Similarity
messages: Belongs to the HMG-CoA lyase family.

1897729:BOX17 RS00315
gene id: 1897729:BOX17_RS00315
uniprot id: A0A1J0VBW0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
messages: Cell inner membrane

1897729:BOX17 RS12300
gene id: 1897729:BOX17_RS12300
uniprot id: A0A1J0VHY6
names: Similarity
messages: Belongs to the creatininase superfamily.

1897729:BOX17 RS08095
gene id: 1897729:BOX17_RS08095
uniprot id: A0A1J0VFU2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ribose 5-phosphate isomerase family.
messages: Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
messages: Homodimer.

1897729:BOX17 RS11600
gene id: 1897729:BOX17_RS11600
uniprot id: A0A1J0VHM9
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

1897729:BOX17 RS11140
gene id: 1897729:BOX17_RS11140
uniprot id: A0A1J0VHE6
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1897729:BOX17 RS12375
gene id: 1897729:BOX17_RS12375
uniprot id: A0A1J0VI04
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1897729:BOX17 RS03810
gene id: 1897729:BOX17_RS03810
uniprot id: A0A1J0VDP0
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

1897729:BOX17 RS08605
gene id: 1897729:BOX17_RS08605
uniprot id: A0A1J0VG28
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

1897729:BOX17 RS07975
gene id: 1897729:BOX17_RS07975
uniprot id: A0A1J0VFV1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

1897729:BOX17 RS05710
gene id: 1897729:BOX17_RS05710
uniprot id: A0A1J0VEN8
names: Subcellular Location Annotation
messages: Membrane

1897729:BOX17 RS10310
gene id: 1897729:BOX17_RS10310
uniprot id: A0A1J0VGX7
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.
messages: This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.

1897729:BOX17 RS12930
gene id: 1897729:BOX17_RS12930
uniprot id: A0A1J0VI93
names: Cofactor
names: Similarity
messages: Belongs to the monomeric-type IDH family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

1897729:BOX17 RS14325
gene id: 1897729:BOX17_RS14325
uniprot id: A0A1J0VJ01
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.

1897729:BOX17 RS10170
gene id: 1897729:BOX17_RS10170
uniprot id: A0A1J0VGY3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

1897729:BOX17 RS10055
gene id: 1897729:BOX17_RS10055
uniprot id: A0A1J0VGV7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

1897729:BOX17 RS01265
gene id: 1897729:BOX17_RS01265
uniprot id: A0A1J0VCF9
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

1897729:BOX17 RS04655
gene id: 1897729:BOX17_RS04655
uniprot id: A0A1J0VE43
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1897729:BOX17 RS14195
gene id: 1897729:BOX17_RS14195
uniprot id: A0A1J0VIV9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm

1897729:BOX17 RS13980
gene id: 1897729:BOX17_RS13980
uniprot id: A0A1J0VIU7
names: Caution
names: Function
names: Similarity
messages: Belongs to the UbiX/PAD1 family.
messages: Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1897729:BOX17 RS00005
gene id: 1897729:BOX17_RS00005
uniprot id: A0A1J0VK36
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Cell inner membrane
messages: Membrane

1897729:BOX17 RS07685
gene id: 1897729:BOX17_RS07685
uniprot id: A0A1J0VFP5
names: Function
names: Similarity
messages: Belongs to the 2H phosphoesterase superfamily. ThpR family.
messages: Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'-phosphomonoester.

1897729:BOX17 RS06920
gene id: 1897729:BOX17_RS06920
uniprot id: A0A1J0VFD2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).

1897729:BOX17 RS08165
gene id: 1897729:BOX17_RS08165
uniprot id: A0A1J0VFW9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

1897729:BOX17 RS08725
gene id: 1897729:BOX17_RS08725
uniprot id: A0A1J0VG71
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

1897729:BOX17 RS10565
gene id: 1897729:BOX17_RS10565
uniprot id: A0A1J0VH35
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseA family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

1897729:BOX17 RS10765
gene id: 1897729:BOX17_RS10765
uniprot id: A0A1J0VH67
names: Similarity
messages: Belongs to the DEAD box helicase family.

1897729:BOX17 RS13915
gene id: 1897729:BOX17_RS13915
uniprot id: A0A1J0VKR9
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1897729:BOX17 RS12370
gene id: 1897729:BOX17_RS12370
uniprot id: A0A1J0VI01
names: Similarity
messages: Belongs to the 3-hydroxyacyl-CoA dehydrogenase family.

1897729:BOX17 RS04530
gene id: 1897729:BOX17_RS04530
uniprot id: A0A1J0VE73
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1897729:BOX17 RS01285
gene id: 1897729:BOX17_RS01285
uniprot id: A0A1J0VCD2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

1897729:BOX17 RS04760
gene id: 1897729:BOX17_RS04760
uniprot id: A0A1J0VE76
names: Subcellular Location Annotation
messages: Membrane

1897729:BOX17 RS15685
gene id: 1897729:BOX17_RS15685
uniprot id: A0A1J0VJP7
names: Function
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
messages: Catalyzes reversively the conversion of L-aspartate beta-semialdehyde (ASA) to L-2,4-diaminobutyrate (DABA) by transamination with L-glutamate.

1897729:BOX17 RS10135
gene id: 1897729:BOX17_RS10135
uniprot id: A0A1J0VGU8
names: Function
names: Similarity
messages: Belongs to the class-I DAHP synthase family.
messages: Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP).

1897729:BOX17 RS09190
gene id: 1897729:BOX17_RS09190
uniprot id: A0A1J0VGG8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

1897729:BOX17 RS11270
gene id: 1897729:BOX17_RS11270
uniprot id: A0A1J0VHH1
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Binds 1 copper ion per subunit, denoted as copper B.
messages: Binds 2 heme groups per subunit, denoted as high- and low-spin.
messages: Membrane

1897729:BOX17 RS09720
gene id: 1897729:BOX17_RS09720
uniprot id: A0A1J0VGM2
names: Similarity
messages: Belongs to the SOS response-associated peptidase family.

1897729:BOX17 RS10200
gene id: 1897729:BOX17_RS10200
uniprot id: A0A1J0VGW8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
messages: Belongs to the ClpX chaperone family. HslU subfamily.
messages: Cytoplasm

1897729:BOX17 RS10075
gene id: 1897729:BOX17_RS10075
uniprot id: A0A1J0VGU4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioester dehydratase family. FabZ subfamily.
messages: Cytoplasm
messages: Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.

1897729:BOX17 RS00090
gene id: 1897729:BOX17_RS00090
uniprot id: A0A1J0VBU3
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.

1897729:BOX17 RS13880
gene id: 1897729:BOX17_RS13880
uniprot id: A0A1J0VIP8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily.
messages: Catalyzes the decarboxylative condensation of pimeloyl-[acyl-carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide.
messages: Homodimer.

1897729:BOX17 RS09080
gene id: 1897729:BOX17_RS09080
uniprot id: A0A1J0VGB1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

1897729:BOX17 RS01590
gene id: 1897729:BOX17_RS01590
uniprot id: A0A1J0VCJ1
names: Function
names: Similarity
messages: Belongs to the DUF177 domain family.
messages: Plays a role in synthesis, processing and/or stability of 23S rRNA.

1897729:BOX17 RS14125
gene id: 1897729:BOX17_RS14125
uniprot id: A0A1J0VIU4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

1897729:BOX17 RS03935
gene id: 1897729:BOX17_RS03935
uniprot id: A0A1J0VDP7
names: Function
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.
messages: Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.

1897729:BOX17 RS15730
gene id: 1897729:BOX17_RS15730
uniprot id: A0A1J0VJN8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1897729:BOX17 RS12630
gene id: 1897729:BOX17_RS12630
uniprot id: A0A1J0VKP4
names: Function
names: Similarity
messages: Belongs to the Dus family. DusA subfamily.
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U20 and U20a in tRNAs.

1897729:BOX17 RS08990
gene id: 1897729:BOX17_RS08990
uniprot id: A0A1J0VG89
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1897729:BOX17 RS13575
gene id: 1897729:BOX17_RS13575
uniprot id: A0A1J0VIN3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

1897729:BOX17 RS15755
gene id: 1897729:BOX17_RS15755
uniprot id: A0A1J0VJN6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TamA family.
messages: Cell outer membrane
messages: Membrane

1897729:BOX17 RS06770
gene id: 1897729:BOX17_RS06770
uniprot id: A0A1J0VF60
names: Similarity
messages: Belongs to the bacterial solute-binding protein 9 family.

1897729:BOX17 RS03605
gene id: 1897729:BOX17_RS03605
uniprot id: A0A1J0VDL4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.
messages: Forms an icosahedral capsid composed of 60 subunits, arranged as a dodecamer of pentamers.

1897729:BOX17 RS14655
gene id: 1897729:BOX17_RS14655
uniprot id: A0A1J0VJ62
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1897729:BOX17 RS09885
gene id: 1897729:BOX17_RS09885
uniprot id: A0A1J0VGR3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the nucleoid occlusion factor SlmA family.
messages: Homodimer. Interacts with FtsZ.
messages: Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid. Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers. SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions.
messages: nucleoid

1897729:BOX17 RS14570
gene id: 1897729:BOX17_RS14570
uniprot id: A0A1J0VJ52
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.

1897729:BOX17 RS11760
gene id: 1897729:BOX17_RS11760
uniprot id: A0A1J0VHQ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial secretin family.
messages: Cell outer membrane
messages: Membrane

1897729:BOX17 RS13460
gene id: 1897729:BOX17_RS13460
uniprot id: A0A1J0VII8
names: Similarity
messages: Belongs to the histone deacetylase family.

1897729:BOX17 RS08650
gene id: 1897729:BOX17_RS08650
uniprot id: A0A1J0VG31
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

1897729:BOX17 RS04595
gene id: 1897729:BOX17_RS04595
uniprot id: A0A1J0VE38
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.

1897729:BOX17 RS03245
gene id: 1897729:BOX17_RS03245
uniprot id: A0A1J0VDE6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-to-5' exoribonuclease specific for small oligoribonucleotides.
messages: Belongs to the oligoribonuclease family.
messages: Cytoplasm

1897729:BOX17 RS11865
gene id: 1897729:BOX17_RS11865
uniprot id: A0A1J0VHQ8
names: Similarity
messages: Belongs to the serine/threonine dehydratase family.

1897729:BOX17 RS06740
gene id: 1897729:BOX17_RS06740
uniprot id: A0A1J0VFA3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the inorganic carbon transporter (TC 9.A.2) DabB family.
messages: Cell membrane
messages: Forms a complex with DabA.
messages: Membrane
messages: Part of an energy-coupled inorganic carbon pump.

1897729:BOX17 RS14285
gene id: 1897729:BOX17_RS14285
uniprot id: A0A1J0VIZ6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the trans-sulfuration enzymes family. MetZ subfamily.
messages: Catalyzes the formation of L-homocysteine from O-succinyl-L-homoserine (OSHS) and hydrogen sulfide.
messages: Homotetramer.

1897729:BOX17 RS09390
gene id: 1897729:BOX17_RS09390
uniprot id: A0A1J0VGI6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

1897729:BOX17 RS11485
gene id: 1897729:BOX17_RS11485
uniprot id: A0A1J0VHI1
names: Similarity
messages: Belongs to the phosphoribulokinase family.

1897729:BOX17 RS13725
gene id: 1897729:BOX17_RS13725
uniprot id: A0A1J0VIP6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

1897729:BOX17 RS01270
gene id: 1897729:BOX17_RS01270
uniprot id: A0A1J0VCE3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer.

1897729:BOX17 RS04275
gene id: 1897729:BOX17_RS04275
uniprot id: A0A1J0VDV9
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1897729:BOX17 RS13035
gene id: 1897729:BOX17_RS13035
uniprot id: A0A1J0VIE6
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Membrane

1897729:BOX17 RS02845
gene id: 1897729:BOX17_RS02845
uniprot id: A0A1J0VD77
names: Similarity
messages: Belongs to the thioredoxin family.

1897729:BOX17 RS04360
gene id: 1897729:BOX17_RS04360
uniprot id: A0A1J0VDY5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

1897729:BOX17 RS08500
gene id: 1897729:BOX17_RS08500
uniprot id: A0A1J0VG55
names: Function
names: Similarity
messages: Belongs to the uroporphyrinogen-III synthase family.
messages: Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.

1897729:BOX17 RS03475
gene id: 1897729:BOX17_RS03475
uniprot id: A0A1J0VDJ1
names: Similarity
messages: Belongs to the Rsd/AlgQ family.

1897729:BOX17 RS12720
gene id: 1897729:BOX17_RS12720
uniprot id: A0A1J0VI54
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

1897729:BOX17 RS09400
gene id: 1897729:BOX17_RS09400
uniprot id: A0A1J0VGK5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1897729:BOX17 RS12170
gene id: 1897729:BOX17_RS12170
uniprot id: A0A1J0VHX7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PNP/UDP phosphorylase family.
messages: Catalyzes the reversible phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.
messages: Homohexamer; trimer of homodimers.

1897729:BOX17 RS10450
gene id: 1897729:BOX17_RS10450
uniprot id: A0A1J0VH01
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ZipA family.
messages: Cell inner membrane
messages: Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins.
messages: Interacts with FtsZ via their C-terminal domains.

1897729:BOX17 RS15430
gene id: 1897729:BOX17_RS15430
uniprot id: A0A1J0VJK2
names: Similarity
messages: Belongs to the Nudix hydrolase family.

1897729:BOX17 RS12550
gene id: 1897729:BOX17_RS12550
uniprot id: A0A1J0VI37
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1897729:BOX17 RS01850
gene id: 1897729:BOX17_RS01850
uniprot id: A0A1J0VCQ0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

1897729:BOX17 RS11145
gene id: 1897729:BOX17_RS11145
uniprot id: A0A1J0VHC6
names: Similarity
messages: Belongs to the KAE1 / TsaD family. TsaB subfamily.

1897729:BOX17 RS03155
gene id: 1897729:BOX17_RS03155
uniprot id: A0A1J0VDD2
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

1897729:BOX17 RS11420
gene id: 1897729:BOX17_RS11420
uniprot id: A0A1J0VHI0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit E family.
messages: Cell membrane
messages: Membrane

1897729:BOX17 RS04295
gene id: 1897729:BOX17_RS04295
uniprot id: A0A1J0VDY7
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1897729:BOX17 RS03620
gene id: 1897729:BOX17_RS03620
uniprot id: A0A1J0VDJ3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

1897729:BOX17 RS12695
gene id: 1897729:BOX17_RS12695
uniprot id: A0A1J0VI59
names: Cofactor
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cell inner membrane
messages: Membrane
messages: Membrane-anchoring subunit of succinate dehydrogenase (SDH).
messages: Part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur protein, plus two membrane-anchoring proteins, SdhC and SdhD.
messages: The heme is bound between the two transmembrane subunits.

1897729:BOX17 RS04180
gene id: 1897729:BOX17_RS04180
uniprot id: A0A1J0VDU4
names: Similarity
messages: Belongs to the GST superfamily.

1897729:BOX17 RS12860
gene id: 1897729:BOX17_RS12860
uniprot id: A0A1J0VI90
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

1897729:BOX17 RS15835
gene id: 1897729:BOX17_RS15835
uniprot id: A0A1J0VJR7
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvA family.
messages: Cytoplasm
messages: Has three domains with a flexible linker between the domains II and III and assumes an 'L' shape. Domain III is highly mobile and contacts RuvB.
messages: Homotetramer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

1897729:BOX17 RS01650
gene id: 1897729:BOX17_RS01650
uniprot id: A0A1J0VCL4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

1897729:BOX17 RS02940
gene id: 1897729:BOX17_RS02940
uniprot id: A0A1J0VK90
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TPMT family.
messages: Cytoplasm

1897729:BOX17 RS01760
gene id: 1897729:BOX17_RS01760
uniprot id: A0A1J0VCM6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane
messages: Membrane

1897729:BOX17 RS04790
gene id: 1897729:BOX17_RS04790
uniprot id: A0A1J0VE56
names: Function
names: Similarity
messages: Belongs to the ATPase gamma chain family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

1897729:BOX17 RS10370
gene id: 1897729:BOX17_RS10370
uniprot id: A0A1J0VH15
names: Caution
names: Function
names: Similarity
messages: Belongs to the Dus family. DusC subfamily.
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U16 in tRNAs.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1897729:BOX17 RS03985
gene id: 1897729:BOX17_RS03985
uniprot id: A0A1J0VDS0
names: Subcellular Location Annotation
messages: Membrane

1897729:BOX17 RS11555
gene id: 1897729:BOX17_RS11555
uniprot id: A0A1J0VHL9
names: Function
names: Similarity
messages: Belongs to the HPPK family.
messages: Catalyzes the transfer of pyrophosphate from adenosine triphosphate (ATP) to 6-hydroxymethyl-7,8-dihydropterin, an enzymatic step in folate biosynthesis pathway.

1897729:BOX17 RS08005
gene id: 1897729:BOX17_RS08005
uniprot id: A0A1J0VFS6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

1897729:BOX17 RS05900
gene id: 1897729:BOX17_RS05900
uniprot id: A0A1J0VEW0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1897729:BOX17 RS15540
gene id: 1897729:BOX17_RS15540
uniprot id: A0A1J0VJL1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the pyridoxamine 5'-phosphate oxidase family.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1897729:BOX17 RS11120
gene id: 1897729:BOX17_RS11120
uniprot id: A0A1J0VHD8
names: Function
names: Similarity
messages: Belongs to the NadC/ModD family.
messages: Involved in the catabolism of quinolinic acid (QA).

1897729:BOX17 RS06915
gene id: 1897729:BOX17_RS06915
uniprot id: A0A1J0VF93
names: Caution
names: Function
names: Similarity
messages: Belongs to the Thz kinase family.
messages: Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1897729:BOX17 RS16190
gene id: 1897729:BOX17_RS16190
uniprot id: A0A1J0VJW9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SURF1 family.
messages: Cell membrane

1897729:BOX17 RS05505
gene id: 1897729:BOX17_RS05505
uniprot id: A0A1J0VEI1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

1897729:BOX17 RS15005
gene id: 1897729:BOX17_RS15005
uniprot id: A0A1J0VJA1
names: Similarity
messages: Belongs to the bacterial sugar transferase family.

1897729:BOX17 RS12935
gene id: 1897729:BOX17_RS12935
uniprot id: A0A1J0VIC6
names: Cofactor
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

1897729:BOX17 RS06090
gene id: 1897729:BOX17_RS06090
uniprot id: A0A1J0VEY8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1897729:BOX17 RS08870
gene id: 1897729:BOX17_RS08870
uniprot id: A0A1J0VG77
names: Similarity
messages: Belongs to the GSP E family.

1897729:BOX17 RS14540
gene id: 1897729:BOX17_RS14540
uniprot id: A0A1J0VJ39
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors.

1897729:BOX17 RS00535
gene id: 1897729:BOX17_RS00535
uniprot id: A0A1J0VC32
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LapB family.
messages: Cell inner membrane
messages: Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane.

1897729:BOX17 RS08015
gene id: 1897729:BOX17_RS08015
uniprot id: A0A1J0VFW0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

1897729:BOX17 RS15115
gene id: 1897729:BOX17_RS15115
uniprot id: A0A1J0VJE2
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1897729:BOX17 RS08545
gene id: 1897729:BOX17_RS08545
uniprot id: A0A1J0VG41
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

1897729:BOX17 RS13660
gene id: 1897729:BOX17_RS13660
uniprot id: A0A1J0VIL0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0014 family.
messages: Membrane

1897729:BOX17 RS02350
gene id: 1897729:BOX17_RS02350
uniprot id: A0A1J0VCZ2
names: Subcellular Location Annotation
messages: Membrane

1897729:BOX17 RS09410
gene id: 1897729:BOX17_RS09410
uniprot id: A0A1J0VGH4
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

1897729:BOX17 RS06615
gene id: 1897729:BOX17_RS06615
uniprot id: A0A1J0VF29
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

1897729:BOX17 RS11445
gene id: 1897729:BOX17_RS11445
uniprot id: A0A1J0VHH3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the DNA photolyase class-1 family.
messages: Binds 1 5,10-methenyltetrahydrofolate (MTHF) per subunit.
messages: Binds 1 FAD per subunit.
messages: May have a photoreceptor function.

1897729:BOX17 RS08010
gene id: 1897729:BOX17_RS08010
uniprot id: A0A1J0VFS7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

1897729:BOX17 RS04265
gene id: 1897729:BOX17_RS04265
uniprot id: A0A1J0VDW9
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. Nitrilase family.

1897729:BOX17 RS09005
gene id: 1897729:BOX17_RS09005
uniprot id: A0A1J0VGB6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

1897729:BOX17 RS04145
gene id: 1897729:BOX17_RS04145
uniprot id: A0A1J0VDW5
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.

1897729:BOX17 RS02030
gene id: 1897729:BOX17_RS02030
uniprot id: A0A1J0VCT7
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

1897729:BOX17 RS03430
gene id: 1897729:BOX17_RS03430
uniprot id: A0A1J0VDG3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1897729:BOX17 RS11025
gene id: 1897729:BOX17_RS11025
uniprot id: A0A1J0VHC1
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

1897729:BOX17 RS02960
gene id: 1897729:BOX17_RS02960
uniprot id: A0A1J0VDA3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

1897729:BOX17 RS10185
gene id: 1897729:BOX17_RS10185
uniprot id: A0A1J0VGY2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiJ family.
messages: Cytoplasm
messages: Required for ubiquinone (coenzyme Q) biosynthesis. Binds hydrophobic ubiquinone biosynthetic intermediates via its SCP2 domain and is essential for the stability of the Ubi complex. May constitute a docking platform where Ubi enzymes assemble and access their SCP2-bound polyprenyl substrates.

1897729:BOX17 RS05835
gene id: 1897729:BOX17_RS05835
uniprot id: A0A1J0VES4
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1897729:BOX17 RS00460
gene id: 1897729:BOX17_RS00460
uniprot id: A0A1J0VK55
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

1897729:BOX17 RS00630
gene id: 1897729:BOX17_RS00630
uniprot id: A0A1J0VC34
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1897729:BOX17 RS03910
gene id: 1897729:BOX17_RS03910
uniprot id: A0A1J0VDQ0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Catalyzes the dehydration of 6-phospho-D-gluconate to 2-dehydro-3-deoxy-6-phospho-D-gluconate.

1897729:BOX17 RS03130
gene id: 1897729:BOX17_RS03130
uniprot id: A0A1J0VDB4
names: Subcellular Location Annotation
messages: Cell inner membrane

1897729:BOX17 RS06075
gene id: 1897729:BOX17_RS06075
uniprot id: A0A1J0VEW2
names: Similarity
messages: Belongs to the peptidase S13 family.

1897729:BOX17 RS01520
gene id: 1897729:BOX17_RS01520
uniprot id: A0A1J0VCK3
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

1897729:BOX17 RS14475
gene id: 1897729:BOX17_RS14475
uniprot id: A0A1J0VJ29
names: Subcellular Location Annotation
messages: Membrane

1897729:BOX17 RS04575
gene id: 1897729:BOX17_RS04575
uniprot id: A0A1J0VE79
names: Cofactor
names: Function
messages: Binds 2 [4Fe-4S] clusters.
messages: Component of a complex that catalyzes the oxidation of glycolate to glyoxylate.

1897729:BOX17 RS04930
gene id: 1897729:BOX17_RS04930
uniprot id: A0A1J0VKC9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1897729:BOX17 RS14960
gene id: 1897729:BOX17_RS14960
uniprot id: A0A1J0VJB2
names: Subcellular Location Annotation
messages: Membrane

1897729:BOX17 RS01940
gene id: 1897729:BOX17_RS01940
uniprot id: A0A1J0VCS6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptA family.
messages: Component of the lipopolysaccharide transport and assembly complex.
messages: Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm.
messages: Periplasm

1897729:BOX17 RS10105
gene id: 1897729:BOX17_RS10105
uniprot id: A0A1J0VGW6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Cytoplasm
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
messages: The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.

1897729:BOX17 RS00920
gene id: 1897729:BOX17_RS00920
uniprot id: A0A1J0VC84
names: Subcellular Location Annotation
messages: Membrane

1897729:BOX17 RS06330
gene id: 1897729:BOX17_RS06330
uniprot id: A0A1J0VF15
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the selenophosphate synthase 1 family. Class I subfamily.
messages: Binds 1 Mg(2+) ion per monomer.
messages: Homodimer.
messages: Synthesizes selenophosphate from selenide and ATP.

1897729:BOX17 RS10425
gene id: 1897729:BOX17_RS10425
uniprot id: A0A1J0VH20
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmF/CycK/Ccl1/NrfE/CcsA family.
messages: Cell inner membrane
messages: Membrane

1897729:BOX17 RS05390
gene id: 1897729:BOX17_RS05390
uniprot id: A0A1J0VEH4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.
messages: Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA.
messages: Cytoplasm
messages: Homodimer.

1897729:BOX17 RS00560
gene id: 1897729:BOX17_RS00560
uniprot id: A0A1J0VC24
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

1897729:BOX17 RS15910
gene id: 1897729:BOX17_RS15910
uniprot id: A0A1J0VJU0
names: Similarity
messages: Belongs to the FPG family.

1897729:BOX17 RS04405
gene id: 1897729:BOX17_RS04405
uniprot id: A0A1J0VE48
names: Similarity
messages: Belongs to the pyruvate kinase family.

1897729:BOX17 RS16205
gene id: 1897729:BOX17_RS16205
uniprot id: A0A1J0VJZ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COX11/CtaG family.
messages: Cell inner membrane
messages: Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I.

1897729:BOX17 RS07830
gene id: 1897729:BOX17_RS07830
uniprot id: A0A1J0VFN8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
messages: Cytoplasm
messages: Homotrimer.
messages: In the C-terminal section; belongs to the transferase hexapeptide repeat family.
messages: In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.

1897729:BOX17 RS09035
gene id: 1897729:BOX17_RS09035
uniprot id: A0A1J0VGA3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

1897729:BOX17 RS01610
gene id: 1897729:BOX17_RS01610
uniprot id: A0A1J0VCL9
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

1897729:BOX17 RS04805
gene id: 1897729:BOX17_RS04805
uniprot id: A0A1J0VE77
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1897729:BOX17 RS06645
gene id: 1897729:BOX17_RS06645
uniprot id: A0A1J0VF45
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1897729:BOX17 RS06985
gene id: 1897729:BOX17_RS06985
uniprot id: A0A1J0VFC8
names: Similarity
messages: Belongs to the peptidase S11 family.

1897729:BOX17 RS02750
gene id: 1897729:BOX17_RS02750
uniprot id: A0A1J0VD51
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

1897729:BOX17 RS02595
gene id: 1897729:BOX17_RS02595
uniprot id: A0A1J0VK62
names: Subcellular Location Annotation
messages: Membrane

1897729:BOX17 RS12970
gene id: 1897729:BOX17_RS12970
uniprot id: A0A1J0VI99
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LolA family.
messages: Monomer.
messages: Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane).
messages: Periplasm

1897729:BOX17 RS13490
gene id: 1897729:BOX17_RS13490
uniprot id: A0A1J0VIM1
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

1897729:BOX17 RS02710
gene id: 1897729:BOX17_RS02710
uniprot id: A0A1J0VD60
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCF family. Uup subfamily.
messages: Cytoplasm
messages: Probably plays a role in ribosome assembly or function. May be involved in resolution of branched DNA intermediates that result from template switching in postreplication gaps. Binds DNA and has ATPase activity.

1897729:BOX17 RS01630
gene id: 1897729:BOX17_RS01630
uniprot id: A0A1J0VCJ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
messages: Belongs to the KdsB family.
messages: Cytoplasm

1897729:BOX17 RS00270
gene id: 1897729:BOX17_RS00270
uniprot id: A0A1J0VBX7
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

1897729:BOX17 RS14120
gene id: 1897729:BOX17_RS14120
uniprot id: A0A1J0VIX6
names: Similarity
messages: Belongs to the YkuD family.

1897729:BOX17 RS01565
gene id: 1897729:BOX17_RS01565
uniprot id: A0A1J0VCL1
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

1897729:BOX17 RS04475
gene id: 1897729:BOX17_RS04475
uniprot id: A0A1J0VE21
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

1897729:BOX17 RS04685
gene id: 1897729:BOX17_RS04685
uniprot id: A0A1J0VE61
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane

1897729:BOX17 RS15220
gene id: 1897729:BOX17_RS15220
uniprot id: A0A1J0VJG2
names: Function
names: Similarity
messages: Belongs to the BCKDHA family.
messages: The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3).

1897729:BOX17 RS03065
gene id: 1897729:BOX17_RS03065
uniprot id: A0A1J0VDA6
names: Subcellular Location Annotation
messages: Membrane

1897729:BOX17 RS08645
gene id: 1897729:BOX17_RS08645
uniprot id: A0A1J0VG76
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

1897729:BOX17 RS00210
gene id: 1897729:BOX17_RS00210
uniprot id: A0A1J0VK41
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A24 family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Plays an essential role in type IV pili and type II pseudopili formation by proteolytically removing the leader sequence from substrate proteins and subsequently monomethylating the alpha-amino group of the newly exposed N-terminal phenylalanine.

1897729:BOX17 RS07550
gene id: 1897729:BOX17_RS07550
uniprot id: A0A1J0VFM2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 3-hydroxyacyl-CoA dehydrogenase family. L-carnitine dehydrogenase subfamily.
messages: Catalyzes the NAD(+)-dependent oxidation of L-carnitine to 3-dehydrocarnitine.
messages: Cytoplasm
messages: Homodimer.

1897729:BOX17 RS04120
gene id: 1897729:BOX17_RS04120
uniprot id: A0A1J0VDZ9
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

1897729:BOX17 RS10320
gene id: 1897729:BOX17_RS10320
uniprot id: A0A1J0VH02
names: Similarity
messages: Belongs to the PhzF family.

1897729:BOX17 RS13580
gene id: 1897729:BOX17_RS13580
uniprot id: A0A1J0VIL8
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1897729:BOX17 RS07540
gene id: 1897729:BOX17_RS07540
uniprot id: A0A1J0VFM3
names: Similarity
messages: Belongs to the gamma-BBH/TMLD family.

1897729:BOX17 RS00050
gene id: 1897729:BOX17_RS00050
uniprot id: A0A1J0VBY0
names: Subcellular Location Annotation
messages: Membrane

1897729:BOX17 RS08280
gene id: 1897729:BOX17_RS08280
uniprot id: A0A1J0VFX3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1897729:BOX17 RS04980
gene id: 1897729:BOX17_RS04980
uniprot id: A0A1J0VEB5
names: Function
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. S-2-haloalkanoic acid dehalogenase family.
messages: Catalyzes the hydrolytic dehalogenation of small (S)-2-haloalkanoic acids to yield the corresponding (R)-2-hydroxyalkanoic acids.

1897729:BOX17 RS08855
gene id: 1897729:BOX17_RS08855
uniprot id: A0A1J0VG91
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

1897729:BOX17 RS06225
gene id: 1897729:BOX17_RS06225
uniprot id: A0A1J0VEX1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
messages: Single-chain monomer with multiple functions.

1897729:BOX17 RS00150
gene id: 1897729:BOX17_RS00150
uniprot id: A0A1J0VBW4
names: Function
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.
messages: Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate.

1897729:BOX17 RS01305
gene id: 1897729:BOX17_RS01305
uniprot id: A0A1J0VCG7
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1897729:BOX17 RS13740
gene id: 1897729:BOX17_RS13740
uniprot id: A0A1J0VIM6
names: Similarity
messages: Belongs to the D-glutamate cyclase family.

1897729:BOX17 RS07865
gene id: 1897729:BOX17_RS07865
uniprot id: A0A1J0VFR4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family. T3SS ATPase subfamily.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has four main subunits: a(1), b(1), b'(1) and c(9-12).
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

1897729:BOX17 RS11350
gene id: 1897729:BOX17_RS11350
uniprot id: A0A1J0VHH9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.
messages: Belongs to the RNR ribonuclease family. RNase R subfamily.
messages: Cytoplasm

1897729:BOX17 RS08345
gene id: 1897729:BOX17_RS08345
uniprot id: A0A1J0VG02
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

1897729:BOX17 RS12730
gene id: 1897729:BOX17_RS12730
uniprot id: A0A1J0VI94
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

1897729:BOX17 RS10710
gene id: 1897729:BOX17_RS10710
uniprot id: A0A1J0VH58
names: Similarity
messages: Belongs to the peptidase A31 family.

1897729:BOX17 RS14415
gene id: 1897729:BOX17_RS14415
uniprot id: A0A1J0VJ19
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1897729:BOX17 RS15860
gene id: 1897729:BOX17_RS15860
uniprot id: A0A1J0VJR6
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1897729:BOX17 RS12670
gene id: 1897729:BOX17_RS12670
uniprot id: A0A1J0VI46
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1897729:BOX17 RS09915
gene id: 1897729:BOX17_RS09915
uniprot id: A0A1J0VGS8
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

1897729:BOX17 RS09420
gene id: 1897729:BOX17_RS09420
uniprot id: A0A1J0VGK3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

1897729:BOX17 RS12310
gene id: 1897729:BOX17_RS12310
uniprot id: A0A1J0VHY0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OpgD/OpgG family.
messages: Periplasm

1897729:BOX17 RS14050
gene id: 1897729:BOX17_RS14050
uniprot id: A0A1J0VIV5
names: Similarity
messages: Belongs to the UPF0250 family.

1897729:BOX17 RS04490
gene id: 1897729:BOX17_RS04490
uniprot id: A0A1J0VE67
names: Similarity
messages: Belongs to the GST superfamily.

1897729:BOX17 RS15850
gene id: 1897729:BOX17_RS15850
uniprot id: A0A1J0VJS6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homodimer.

1897729:BOX17 RS02200
gene id: 1897729:BOX17_RS02200
uniprot id: A0A1J0VCX1
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

1897729:BOX17 RS09990
gene id: 1897729:BOX17_RS09990
uniprot id: A0A1J0VGS3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M20A family. DapE subfamily.
messages: Binds 2 Zn(2+) or Co(2+) ions per subunit.
messages: Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls.
messages: Homodimer.

1897729:BOX17 RS03855
gene id: 1897729:BOX17_RS03855
uniprot id: A0A1J0VDP6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsB family.
messages: Cell inner membrane
messages: Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.
messages: Part of a complex composed of FtsB, FtsL and FtsQ.

1897729:BOX17 RS14510
gene id: 1897729:BOX17_RS14510
uniprot id: A0A1J0VJ21
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.

1897729:BOX17 RS14435
gene id: 1897729:BOX17_RS14435
uniprot id: A0A1J0VJ22
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the urease gamma subunit family.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

1897729:BOX17 RS01570
gene id: 1897729:BOX17_RS01570
uniprot id: A0A1J0VCK1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

1897729:BOX17 RS01720
gene id: 1897729:BOX17_RS01720
uniprot id: A0A1J0VCM8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

1897729:BOX17 RS06735
gene id: 1897729:BOX17_RS06735
uniprot id: A0A1J0VF61
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1897729:BOX17 RS03675
gene id: 1897729:BOX17_RS03675
uniprot id: A0A1J0VDS2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Membrane

1897729:BOX17 RS02795
gene id: 1897729:BOX17_RS02795
uniprot id: A0A1J0VD62
names: Similarity
messages: Belongs to the PrpD family.

1897729:BOX17 RS00905
gene id: 1897729:BOX17_RS00905
uniprot id: A0A1J0VCB7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1897729:BOX17 RS12790
gene id: 1897729:BOX17_RS12790
uniprot id: A0A1J0VI73
names: Similarity
messages: Belongs to the universal stress protein A family.

1897729:BOX17 RS03215
gene id: 1897729:BOX17_RS03215
uniprot id: A0A1J0VDD6
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1897729:BOX17 RS12975
gene id: 1897729:BOX17_RS12975
uniprot id: A0A1J0VI98
names: Function
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.
messages: DNA-dependent ATPase that plays important roles in cellular responses to stalled DNA replication processes.

1897729:BOX17 RS11945
gene id: 1897729:BOX17_RS11945
uniprot id: A0A1J0VHS4
names: Subcellular Location Annotation
messages: Cytoplasm

1897729:BOX17 RS03615
gene id: 1897729:BOX17_RS03615
uniprot id: A0A1J0VKA7
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion.
messages: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.
messages: In the C-terminal section; belongs to the HTP reductase family.
messages: In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family.

1897729:BOX17 RS14865
gene id: 1897729:BOX17_RS14865
uniprot id: A0A1J0VJ99
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the etk/wzc family.
messages: Cell inner membrane
messages: Membrane

1897729:BOX17 RS03645
gene id: 1897729:BOX17_RS03645
uniprot id: A0A1J0VDK7
names: PTM
messages: Binds 2 heme c groups covalently per subunit.

1897729:BOX17 RS07140
gene id: 1897729:BOX17_RS07140
uniprot id: A0A1J0VFC9
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

1897729:BOX17 RS05395
gene id: 1897729:BOX17_RS05395
uniprot id: A0A1J0VEI8
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

1897729:BOX17 RS05340
gene id: 1897729:BOX17_RS05340
uniprot id: A0A1J0VEF2
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1897729:BOX17 RS15800
gene id: 1897729:BOX17_RS15800
uniprot id: A0A1J0VJR9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CpoB family.
messages: Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division.
messages: Periplasm

1897729:BOX17 RS12045
gene id: 1897729:BOX17_RS12045
uniprot id: A0A1J0VHV2
names: Similarity
messages: Belongs to the DEAD box helicase family.

1897729:BOX17 RS06430
gene id: 1897729:BOX17_RS06430
uniprot id: A0A1J0VEZ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

1897729:BOX17 RS03230
gene id: 1897729:BOX17_RS03230
uniprot id: A0A1J0VDF3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm

1897729:BOX17 RS10330
gene id: 1897729:BOX17_RS10330
uniprot id: A0A1J0VGZ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

1897729:BOX17 RS04975
gene id: 1897729:BOX17_RS04975
uniprot id: A0A1J0VEA2
names: Similarity
messages: Belongs to the GST superfamily. NadH family.

1897729:BOX17 RS15940
gene id: 1897729:BOX17_RS15940
uniprot id: A0A1J0VJU2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
messages: Cytoplasm
messages: Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.

1897729:BOX17 RS04680
gene id: 1897729:BOX17_RS04680
uniprot id: A0A1J0VE54
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Membrane

1897729:BOX17 RS11000
gene id: 1897729:BOX17_RS11000
uniprot id: A0A1J0VH96
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: In the N-terminal section; belongs to the FGAMS family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.

1897729:BOX17 RS09445
gene id: 1897729:BOX17_RS09445
uniprot id: A0A1J0VGL3
names: Function
names: Similarity
messages: Belongs to the RibF family.
messages: Catalyzes the phosphorylation of riboflavin to FMN followed by the adenylation of FMN to FAD.

1897729:BOX17 RS00175
gene id: 1897729:BOX17_RS00175
uniprot id: A0A1J0VBV9
names: Similarity
messages: Belongs to the HIBADH-related family.

1897729:BOX17 RS06300
gene id: 1897729:BOX17_RS06300
uniprot id: A0A1J0VF01
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

1897729:BOX17 RS08880
gene id: 1897729:BOX17_RS08880
uniprot id: A0A1J0VG97
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 2 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

1897729:BOX17 RS15160
gene id: 1897729:BOX17_RS15160
uniprot id: A0A1J0VJE3
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

1897729:BOX17 RS10175
gene id: 1897729:BOX17_RS10175
uniprot id: A0A1J0VGV6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRA-PH family.
messages: Cytoplasm

1897729:BOX17 RS14365
gene id: 1897729:BOX17_RS14365
uniprot id: A0A1J0VIY7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RlpA family.
messages: Cell membrane
messages: Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides.

1897729:BOX17 RS04350
gene id: 1897729:BOX17_RS04350
uniprot id: A0A1J0VDZ6
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.

1897729:BOX17 RS09840
gene id: 1897729:BOX17_RS09840
uniprot id: A0A1J0VGQ6
names: Similarity
messages: Belongs to the BolA/IbaG family.

1897729:BOX17 RS09700
gene id: 1897729:BOX17_RS09700
uniprot id: A0A1J0VGN2
names: Function
names: Similarity
names: Subunit
messages: ATPase required for the correct placement of the division site. Cell division inhibitors MinC and MinD act in concert to form an inhibitor capable of blocking formation of the polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings.
messages: Belongs to the ParA family. MinD subfamily.
messages: Interacts with MinC and FtsZ.

1897729:BOX17 RS15780
gene id: 1897729:BOX17_RS15780
uniprot id: A0A1J0VJR1
names: Similarity
messages: Belongs to the UDPGP type 2 family.

1897729:BOX17 RS11705
gene id: 1897729:BOX17_RS11705
uniprot id: A0A1J0VKP3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1897729:BOX17 RS14215
gene id: 1897729:BOX17_RS14215
uniprot id: A0A1J0VIW2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

1897729:BOX17 RS03635
gene id: 1897729:BOX17_RS03635
uniprot id: A0A1J0VDR4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbC subfamily.
messages: Periplasm
messages: Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process.

1897729:BOX17 RS10240
gene id: 1897729:BOX17_RS10240
uniprot id: A0A1J0VGY6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits).
messages: In the C-terminal section; belongs to the transpeptidase family.
messages: In the N-terminal section; belongs to the glycosyltransferase 51 family.
messages: Membrane

1897729:BOX17 RS00285
gene id: 1897729:BOX17_RS00285
uniprot id: A0A1J0VK43
names: Subcellular Location Annotation
messages: Membrane

1897729:BOX17 RS08835
gene id: 1897729:BOX17_RS08835
uniprot id: A0A1J0VG88
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

1897729:BOX17 RS14060
gene id: 1897729:BOX17_RS14060
uniprot id: A0A1J0VIT8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

1897729:BOX17 RS15595
gene id: 1897729:BOX17_RS15595
uniprot id: A0A1J0VJN3
names: Domain
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 dependent methionine synthase family.
messages: Catalyzes the transfer of a methyl group from methyl-cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
messages: Modular enzyme with four functionally distinct domains. The isolated Hcy-binding domain catalyzes methyl transfer from free methylcobalamin to homocysteine. The Hcy-binding domain in association with the pterin-binding domain catalyzes the methylation of cob(I)alamin by methyltetrahydrofolate and the methylation of homocysteine. The B12-binding domain binds the cofactor. The AdoMet activation domain binds S-adenosyl-L-methionine. Under aerobic conditions cob(I)alamin can be converted to inactive cob(II)alamin. Reductive methylation by S-adenosyl-L-methionine and flavodoxin regenerates methylcobalamin.

1897729:BOX17 RS14135
gene id: 1897729:BOX17_RS14135
uniprot id: A0A1J0VIX0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NqrA family.
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

1897729:BOX17 RS13510
gene id: 1897729:BOX17_RS13510
uniprot id: A0A1J0VIK8
names: Similarity
messages: Belongs to the peptidase S9A family.

1897729:BOX17 RS16210
gene id: 1897729:BOX17_RS16210
uniprot id: A0A1J0VJY0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Cell membrane
messages: Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.
messages: Membrane

1897729:BOX17 RS08100
gene id: 1897729:BOX17_RS08100
uniprot id: A0A1J0VFX8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the serine/threonine dehydratase family.
messages: Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.
messages: Homotetramer.

1897729:BOX17 RS11365
gene id: 1897729:BOX17_RS11365
uniprot id: A0A1J0VHI5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein bS6.

1897729:BOX17 RS16230
gene id: 1897729:BOX17_RS16230
uniprot id: A0A1J0VJY7
names: Subcellular Location Annotation
messages: Membrane

1897729:BOX17 RS09455
gene id: 1897729:BOX17_RS09455
uniprot id: A0A1J0VKK4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell membrane
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

1897729:BOX17 RS10115
gene id: 1897729:BOX17_RS10115
uniprot id: A0A1J0VGW7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.

1897729:BOX17 RS14350
gene id: 1897729:BOX17_RS14350
uniprot id: A0A1J0VJ05
names: Similarity
messages: Belongs to the CFA/CMAS family.

1897729:BOX17 RS00140
gene id: 1897729:BOX17_RS00140
uniprot id: A0A1J0VBZ5
names: Similarity
messages: Belongs to the peptidase S16 family.

1897729:BOX17 RS06535
gene id: 1897729:BOX17_RS06535
uniprot id: A0A1J0VF24
names: Similarity
messages: Belongs to the SUI1 family.

1897729:BOX17 RS11540
gene id: 1897729:BOX17_RS11540
uniprot id: A0A1J0VHK7
names: Function
names: Similarity
messages: Belongs to the Ap4A hydrolase family.
messages: Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP.

1897729:BOX17 RS09000
gene id: 1897729:BOX17_RS09000
uniprot id: A0A1J0VGC4
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1897729:BOX17 RS08000
gene id: 1897729:BOX17_RS08000
uniprot id: A0A1J0VFX2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RnpA family.
messages: Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.
messages: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.

1897729:BOX17 RS10575
gene id: 1897729:BOX17_RS10575
uniprot id: A0A1J0VH24
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

1897729:BOX17 RS07040
gene id: 1897729:BOX17_RS07040
uniprot id: A0A1J0VFB3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
messages: Cell membrane
messages: Membrane

1897729:BOX17 RS07165
gene id: 1897729:BOX17_RS07165
uniprot id: A0A1J0VFH2
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

1897729:BOX17 RS13950
gene id: 1897729:BOX17_RS13950
uniprot id: A0A1J0VIU3
names: Subcellular Location Annotation
messages: Membrane

1897729:BOX17 RS15840
gene id: 1897729:BOX17_RS15840
uniprot id: A0A1J0VJQ6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvC family.
messages: Binds 2 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer which binds Holliday junction (HJ) DNA. The HJ becomes 2-fold symmetrical on binding to RuvC with unstacked arms; it has a different conformation from HJ DNA in complex with RuvA. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair. Endonuclease that resolves HJ intermediates. Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction. The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'. Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange. HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

1897729:BOX17 RS02160
gene id: 1897729:BOX17_RS02160
uniprot id: A0A1J0VCX0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1897729:BOX17 RS14700
gene id: 1897729:BOX17_RS14700
uniprot id: A0A1J0VJ70
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

1897729:BOX17 RS02805
gene id: 1897729:BOX17_RS02805
uniprot id: A0A1J0VDA4
names: Function
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.
messages: Catalyzes the isomerization of citrate to isocitrate via cis-aconitate.

1897729:BOX17 RS04335
gene id: 1897729:BOX17_RS04335
uniprot id: A0A1J0VDX8
names: Similarity
messages: Belongs to the universal stress protein A family.

1897729:BOX17 RS02680
gene id: 1897729:BOX17_RS02680
uniprot id: A0A1J0VD49
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. Thiolase family.
messages: Catalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed.
messages: Cytoplasm
messages: Heterotetramer of two alpha chains (FadB) and two beta chains (FadA).

1897729:BOX17 RS10960
gene id: 1897729:BOX17_RS10960
uniprot id: A0A1J0VH94
names: Cofactor
messages: Binds 1 Fe(2+) ion per subunit.

1897729:BOX17 RS11430
gene id: 1897729:BOX17_RS11430
uniprot id: A0A1J0VHJ5
names: Subcellular Location Annotation
messages: Membrane

1897729:BOX17 RS13100
gene id: 1897729:BOX17_RS13100
uniprot id: A0A1J0VIF1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell inner membrane
messages: Membrane

1897729:BOX17 RS14140
gene id: 1897729:BOX17_RS14140
uniprot id: A0A1J0VIV6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrB/RnfD family.
messages: Cell membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

1897729:BOX17 RS06585
gene id: 1897729:BOX17_RS06585
uniprot id: A0A1J0VF55
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Member of the two-component regulatory system NtrB/NtrC, which controls expression of the nitrogen-regulated (ntr) genes in response to nitrogen limitation. Phosphorylated NtrC binds directly to DNA and stimulates the formation of open promoter-sigma54-RNA polymerase complexes.

1897729:BOX17 RS14880
gene id: 1897729:BOX17_RS14880
uniprot id: A0A1J0VJA3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Binds 1 Mg(2+) ion per monomer.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

1897729:BOX17 RS16085
gene id: 1897729:BOX17_RS16085
uniprot id: A0A1J0VJX0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell inner membrane
messages: Membrane

1897729:BOX17 RS07525
gene id: 1897729:BOX17_RS07525
uniprot id: A0A1J0VFN4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CpxP/Spy family.
messages: Periplasm

1897729:BOX17 RS11960
gene id: 1897729:BOX17_RS11960
uniprot id: A0A1J0VKN5
names: Subcellular Location Annotation
messages: Membrane

1897729:BOX17 RS14690
gene id: 1897729:BOX17_RS14690
uniprot id: A0A1J0VJ56
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MobA family.
messages: Cytoplasm
messages: Monomer.
messages: The N-terminal domain determines nucleotide recognition and specific binding, while the C-terminal domain determines the specific binding to the target protein.
messages: Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor.

1897729:BOX17 RS09520
gene id: 1897729:BOX17_RS09520
uniprot id: A0A1J0VGM0
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

1897729:BOX17 RS05315
gene id: 1897729:BOX17_RS05315
uniprot id: A0A1J0VEG3
names: Similarity
messages: Belongs to the glutathione peroxidase family.

1897729:BOX17 RS00325
gene id: 1897729:BOX17_RS00325
uniprot id: A0A1J0VC25
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1897729:BOX17 RS00395
gene id: 1897729:BOX17_RS00395
uniprot id: A0A1J0VC17
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1897729:BOX17 RS06505
gene id: 1897729:BOX17_RS06505
uniprot id: A0A1J0VF21
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class II fructose-bisphosphate aldolase family.
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.
messages: Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.
messages: One is catalytic and the other provides a structural contribution.

1897729:BOX17 RS09860
gene id: 1897729:BOX17_RS09860
uniprot id: A0A1J0VGP9
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily. RsmD family.
messages: Specifically methylates the guanine in position 966 of 16S rRNA in the assembled 30S particle.

1897729:BOX17 RS11595
gene id: 1897729:BOX17_RS11595
uniprot id: A0A1J0VHK8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1897729:BOX17 RS02505
gene id: 1897729:BOX17_RS02505
uniprot id: A0A1J0VD18
names: Cofactor
names: Similarity
messages: Belongs to the RimK family.
messages: Binds 2 magnesium or manganese ions per subunit.

1897729:BOX17 RS16215
gene id: 1897729:BOX17_RS16215
uniprot id: A0A1J0VJZ7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 2 family.
messages: Binds a copper A center.
messages: Cell membrane
messages: Membrane
messages: Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B).

1897729:BOX17 RS07110
gene id: 1897729:BOX17_RS07110
uniprot id: A0A1J0VFC7
names: Similarity
messages: Belongs to the CbbQ/NirQ/NorQ/GpvN family.

1897729:BOX17 RS12360
gene id: 1897729:BOX17_RS12360
uniprot id: A0A1J0VI23
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1897729:BOX17 RS07680
gene id: 1897729:BOX17_RS07680
uniprot id: A0A1J0VFM4
names: Similarity
messages: Belongs to the RutC family.

1897729:BOX17 RS08245
gene id: 1897729:BOX17_RS08245
uniprot id: A0A1J0VG03
names: Similarity
messages: Belongs to the GST superfamily.

1897729:BOX17 RS13315
gene id: 1897729:BOX17_RS13315
uniprot id: A0A1J0VIG9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

1897729:BOX17 RS09095
gene id: 1897729:BOX17_RS09095
uniprot id: A0A1J0VGD9
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

1897729:BOX17 RS08965
gene id: 1897729:BOX17_RS08965
uniprot id: A0A1J0VGC8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

1897729:BOX17 RS03105
gene id: 1897729:BOX17_RS03105
uniprot id: A0A1J0VDB2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LemA family.
messages: Membrane

1897729:BOX17 RS09180
gene id: 1897729:BOX17_RS09180
uniprot id: A0A1J0VGE5
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

1897729:BOX17 RS14630
gene id: 1897729:BOX17_RS14630
uniprot id: A0A1J0VJ57
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. XGPT subfamily.
messages: Cell membrane
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Purine salvage pathway enzyme that catalyzes the transfer of the ribosyl-5-phosphate group from 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to the N9 position of the 6-oxopurines guanine and xanthine to form the corresponding ribonucleotides GMP (guanosine 5'-monophosphate) and XMP (xanthosine 5'-monophosphate), with the release of PPi. To a lesser extent, also acts on hypoxanthine.

1897729:BOX17 RS07810
gene id: 1897729:BOX17_RS07810
uniprot id: A0A1J0VFS1
names: Similarity
messages: Belongs to the 2-oxoadipate dioxygenase/decarboxylase family.

1897729:BOX17 RS07730
gene id: 1897729:BOX17_RS07730
uniprot id: A0A1J0VFP8
names: Function
messages: This protein is a positive regulator for the phosphate regulon. Transcription of this operon is positively regulated by PhoB and PhoR when phosphate is limited.

1897729:BOX17 RS14675
gene id: 1897729:BOX17_RS14675
uniprot id: A0A1J0VJ66
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.

1897729:BOX17 RS08520
gene id: 1897729:BOX17_RS08520
uniprot id: A0A1J0VG14
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fluoride channel Fluc/FEX (TC 1.A.43) family.
messages: Cell membrane
messages: Fluoride-specific ion channel. Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane
messages: Na(+) is not transported, but it plays an essential structural role and its presence is essential for fluoride channel function.

1897729:BOX17 RS05480
gene id: 1897729:BOX17_RS05480
uniprot id: A0A1J0VEJ6
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the shikimate dehydrogenase family.
messages: Homodimer.
messages: Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1897729:BOX17 RS08575
gene id: 1897729:BOX17_RS08575
uniprot id: A0A1J0VG37
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

1897729:BOX17 RS13565
gene id: 1897729:BOX17_RS13565
uniprot id: A0A1J0VIJ7
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Bcr/CmlA family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1897729:BOX17 RS12175
gene id: 1897729:BOX17_RS12175
uniprot id: A0A1J0VHW3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phosphopentomutase family.
messages: Binds 1 or 2 manganese ions.
messages: Cytoplasm
messages: Phosphotransfer between the C1 and C5 carbon atoms of pentose.

1897729:BOX17 RS10010
gene id: 1897729:BOX17_RS10010
uniprot id: A0A1J0VGV1
names: Activity Regulation
names: Caution
names: Domain
names: Function
names: Similarity
messages: Belongs to the GlnD family.
messages: Has four distinct domains: an N-terminal nucleotidyltransferase (NT) domain responsible for UTase activity, a central HD domain that encodes UR activity, and two C-terminal ACT domains that seem to have a role in glutamine sensing.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen metabolism.
messages: Uridylyltransferase (UTase) activity is inhibited by glutamine, while glutamine activates uridylyl-removing (UR) activity.

1897729:BOX17 RS13730
gene id: 1897729:BOX17_RS13730
uniprot id: A0A1J0VIP1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

1897729:BOX17 RS02180
gene id: 1897729:BOX17_RS02180
uniprot id: A0A1J0VCZ0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1897729:BOX17 RS08735
gene id: 1897729:BOX17_RS08735
uniprot id: A0A1J0VG90
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

1897729:BOX17 RS06055
gene id: 1897729:BOX17_RS06055
uniprot id: A0A1J0VET2
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

1897729:BOX17 RS09055
gene id: 1897729:BOX17_RS09055
uniprot id: A0A1J0VGC1
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: Methylated by PrmB.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

1897729:BOX17 RS16045
gene id: 1897729:BOX17_RS16045
uniprot id: A0A1J0VJV5
names: Similarity
messages: Belongs to the 2-oxoadipate dioxygenase/decarboxylase family.

1897729:BOX17 RS04840
gene id: 1897729:BOX17_RS04840
uniprot id: A0A1J0VE90
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1897729:BOX17 RS15355
gene id: 1897729:BOX17_RS15355
uniprot id: A0A1J0VJG4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Monomer.
messages: Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl-glutathione to form glutathione and D-lactic acid.

1897729:BOX17 RS05345
gene id: 1897729:BOX17_RS05345
uniprot id: A0A1J0VEG7
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1897729:BOX17 RS10020
gene id: 1897729:BOX17_RS10020
uniprot id: A0A1J0VGT9
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

1897729:BOX17 RS11465
gene id: 1897729:BOX17_RS11465
uniprot id: A0A1J0VHI9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

1897729:BOX17 RS12125
gene id: 1897729:BOX17_RS12125
uniprot id: A0A1J0VHV8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SbcD family.
messages: Heterodimer of SbcC and SbcD.
messages: SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity.

1897729:BOX17 RS06010
gene id: 1897729:BOX17_RS06010
uniprot id: A0A1J0VES2
names: Similarity
messages: Belongs to the intradiol ring-cleavage dioxygenase family.

1897729:BOX17 RS11375
gene id: 1897729:BOX17_RS11375
uniprot id: A0A1J0VHH7
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

1897729:BOX17 RS03270
gene id: 1897729:BOX17_RS03270
uniprot id: A0A1J0VDG2
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Alleviates ribosome stalling that occurs when 3 or more consecutive Pro residues or the sequence PPG is present in a protein, possibly by augmenting the peptidyl transferase activity of the ribosome. Modification of Lys-34 is required for alleviation.
messages: May be beta-lysylated on the epsilon-amino group of Lys-34 by the combined action of EpmA and EpmB, and then hydroxylated on the C5 position of the same residue by EpmC (if this protein is present). Lysylation is critical for the stimulatory effect of EF-P on peptide-bond formation. The lysylation moiety may extend toward the peptidyltransferase center and stabilize the terminal 3-CCA end of the tRNA. Hydroxylation of the C5 position on Lys-34 may allow additional potential stabilizing hydrogen-bond interactions with the P-tRNA.

1897729:BOX17 RS15150
gene id: 1897729:BOX17_RS15150
uniprot id: A0A1J0VJC5
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

1897729:BOX17 RS02055
gene id: 1897729:BOX17_RS02055
uniprot id: A0A1J0VCU3
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

1897729:BOX17 RS07650
gene id: 1897729:BOX17_RS07650
uniprot id: A0A1J0VFL4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase PH family.
messages: Homohexameric ring arranged as a trimer of dimers.
messages: Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.

1897729:BOX17 RS15630
gene id: 1897729:BOX17_RS15630
uniprot id: A0A1J0VJL2
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Fur family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.

1897729:BOX17 RS07635
gene id: 1897729:BOX17_RS07635
uniprot id: A0A1J0VFP2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S-adenosyl-L-methionine to the 2'-OH of the wobble nucleotide.

1897729:BOX17 RS06320
gene id: 1897729:BOX17_RS06320
uniprot id: A0A1J0VEY0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1897729:BOX17 RS00205
gene id: 1897729:BOX17_RS00205
uniprot id: A0A1J0VBV8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 3 family. NagZ subfamily.
messages: Cytoplasm
messages: Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide-linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N-acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides.

1897729:BOX17 RS06165
gene id: 1897729:BOX17_RS06165
uniprot id: A0A1J0VEU7
names: Similarity
messages: Belongs to the glycerate kinase type-1 family.

1897729:BOX17 RS06140
gene id: 1897729:BOX17_RS06140
uniprot id: A0A1J0VEU8
names: Similarity
messages: Belongs to the EcnA/EcnB lipoprotein family.

1897729:BOX17 RS01725
gene id: 1897729:BOX17_RS01725
uniprot id: A0A1J0VCR9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.
messages: Cell membrane
messages: Self-interacts. Interacts with FtsZ.

1897729:BOX17 RS05740
gene id: 1897729:BOX17_RS05740
uniprot id: A0A1J0VEQ9
names: Subcellular Location Annotation
messages: Membrane

1897729:BOX17 RS09600
gene id: 1897729:BOX17_RS09600
uniprot id: A0A1J0VGL8
names: Similarity
messages: Belongs to the UPF0246 family.

1897729:BOX17 RS01375
gene id: 1897729:BOX17_RS01375
uniprot id: A0A1J0VCE9
names: Subcellular Location Annotation
messages: Membrane

1897729:BOX17 RS10145
gene id: 1897729:BOX17_RS10145
uniprot id: A0A1J0VGX3
names: Function
names: PTM
names: Similarity
messages: An intermediate of this reaction is the autophosphorylated ppk in which a phosphate is covalently linked to a histidine residue through a N-P bond.
messages: Belongs to the polyphosphate kinase 1 (PPK1) family.
messages: Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP).

1897729:BOX17 RS15270
gene id: 1897729:BOX17_RS15270
uniprot id: A0A1J0VJG8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LamB/PxpA family.
messages: Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.
messages: Forms a complex composed of PxpA, PxpB and PxpC.

1897729:BOX17 RS03490
gene id: 1897729:BOX17_RS03490
uniprot id: A0A1J0VDN7
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1897729:BOX17 RS07570
gene id: 1897729:BOX17_RS07570
uniprot id: A0A1J0VFK2
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M20 family.
messages: Binds 2 Zn(2+) ions per subunit.

1897729:BOX17 RS11135
gene id: 1897729:BOX17_RS11135
uniprot id: A0A1J0VHC9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 3 lipoyl cofactors covalently.
messages: Forms a 24-polypeptide structural core with octahedral symmetry.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).

1897729:BOX17 RS11475
gene id: 1897729:BOX17_RS11475
uniprot id: A0A1J0VHK3
names: Similarity
messages: Belongs to the GARS family.

1897729:BOX17 RS13560
gene id: 1897729:BOX17_RS13560
uniprot id: A0A1J0VIJ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 1 subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

1897729:BOX17 RS15820
gene id: 1897729:BOX17_RS15820
uniprot id: A0A1J0VJS3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ExbD/TolR family.
messages: Cell inner membrane
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

1897729:BOX17 RS12420
gene id: 1897729:BOX17_RS12420
uniprot id: A0A1J0VI13
names: Subcellular Location Annotation
messages: Membrane

1897729:BOX17 RS08865
gene id: 1897729:BOX17_RS08865
uniprot id: A0A1J0VG74
names: Similarity
messages: Belongs to the GSP E family.

1897729:BOX17 RS10460
gene id: 1897729:BOX17_RS10460
uniprot id: A0A1J0VH27
names: Similarity
messages: Belongs to the UPF0270 family.

1897729:BOX17 RS03300
gene id: 1897729:BOX17_RS03300
uniprot id: A0A1J0VDE3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family. ParE type 1 subfamily.
messages: Heterotetramer composed of ParC and ParE.
messages: Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.

1897729:BOX17 RS15805
gene id: 1897729:BOX17_RS15805
uniprot id: A0A1J0VJR8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Pal lipoprotein family.
messages: Cell outer membrane
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

1897729:BOX17 RS10430
gene id: 1897729:BOX17_RS10430
uniprot id: A0A1J0VH10
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbE subfamily.
messages: Cell inner membrane

1897729:BOX17 RS16235
gene id: 1897729:BOX17_RS16235
uniprot id: A0A1J0VKU7
names: Subcellular Location Annotation
messages: Membrane

1897729:BOX17 RS16455
gene id: 1897729:BOX17_RS16455
uniprot id: A0A1J0VK29
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

1897729:BOX17 RS10785
gene id: 1897729:BOX17_RS10785
uniprot id: A0A1J0VH61
names: Similarity
messages: Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family.

1897729:BOX17 RS03730
gene id: 1897729:BOX17_RS03730
uniprot id: A0A1J0VDM4
names: Subcellular Location Annotation
messages: Membrane

1897729:BOX17 RS08530
gene id: 1897729:BOX17_RS08530
uniprot id: A0A1J0VG30
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm

1897729:BOX17 RS10445
gene id: 1897729:BOX17_RS10445
uniprot id: A0A1J0VH04
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.

1897729:BOX17 RS12835
gene id: 1897729:BOX17_RS12835
uniprot id: A0A1J0VI97
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

1897729:BOX17 RS01675
gene id: 1897729:BOX17_RS01675
uniprot id: A0A1J0VCK8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

1897729:BOX17 RS14320
gene id: 1897729:BOX17_RS14320
uniprot id: A0A1J0VIX8
names: Function
names: Similarity
messages: Belongs to the DadA oxidoreductase family.
messages: Oxidative deamination of D-amino acids.

1897729:BOX17 RS02645
gene id: 1897729:BOX17_RS02645
uniprot id: A0A1J0VD36
names: Similarity
messages: Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family. Type 2 subfamily.

1897729:BOX17 RS15690
gene id: 1897729:BOX17_RS15690
uniprot id: A0A1J0VJN0
names: Function
names: Similarity
messages: Belongs to the acetyltransferase family. EctA subfamily.
messages: Catalyzes the acetylation of L-2,4-diaminobutyrate (DABA) to gamma-N-acetyl-alpha,gamma-diaminobutyric acid (ADABA) with acetyl coenzyme A.

1897729:BOX17 RS01040
gene id: 1897729:BOX17_RS01040
uniprot id: A0A1J0VCC1
names: Subcellular Location Annotation
messages: Membrane

1897729:BOX17 RS16330
gene id: 1897729:BOX17_RS16330
uniprot id: A0A1J0VK08
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1897729:BOX17 RS08085
gene id: 1897729:BOX17_RS08085
uniprot id: A0A1J0VFY7
names: Function
names: Similarity
names: Subunit
messages: Catalyzes the ADP transfer from ATP to D-glycero-beta-D-manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose.
messages: Catalyzes the phosphorylation of D-glycero-D-manno-heptose 7-phosphate at the C-1 position to selectively form D-glycero-beta-D-manno-heptose-1,7-bisphosphate.
messages: Homodimer.
messages: In the C-terminal section; belongs to the cytidylyltransferase family.
messages: In the N-terminal section; belongs to the carbohydrate kinase PfkB family.

1897729:BOX17 RS08765
gene id: 1897729:BOX17_RS08765
uniprot id: A0A1J0VG78
names: Function
names: Similarity
messages: Belongs to the HPPK family.
messages: Catalyzes the transfer of pyrophosphate from adenosine triphosphate (ATP) to 6-hydroxymethyl-7,8-dihydropterin, an enzymatic step in folate biosynthesis pathway.

1897729:BOX17 RS04105
gene id: 1897729:BOX17_RS04105
uniprot id: A0A1J0VDV5
names: Function
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. S-2-haloalkanoic acid dehalogenase family.
messages: Catalyzes the hydrolytic dehalogenation of small (S)-2-haloalkanoic acids to yield the corresponding (R)-2-hydroxyalkanoic acids.

1897729:BOX17 RS13750
gene id: 1897729:BOX17_RS13750
uniprot id: A0A1J0VIQ6
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1897729:BOX17 RS06435
gene id: 1897729:BOX17_RS06435
uniprot id: A0A1J0VF04
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

1897729:BOX17 RS15470
gene id: 1897729:BOX17_RS15470
uniprot id: A0A1J0VJK6
names: Function
names: Similarity
messages: Belongs to the MoaB/Mog family.
messages: May be involved in the biosynthesis of molybdopterin.

1897729:BOX17 RS03905
gene id: 1897729:BOX17_RS03905
uniprot id: A0A1J0VDW1
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1897729:BOX17 RS05015
gene id: 1897729:BOX17_RS05015
uniprot id: A0A1J0VEB0
names: Function
names: Similarity
names: Subunit
messages: A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD.
messages: Belongs to the RecD family.
messages: Heterotrimer of RecB, RecC and RecD. All subunits contribute to DNA-binding.

1897729:BOX17 RS12065
gene id: 1897729:BOX17_RS12065
uniprot id: A0A1J0VHV4
names: Cofactor
messages: Binds 1 zinc ion per subunit.

1897729:BOX17 RS14355
gene id: 1897729:BOX17_RS14355
uniprot id: A0A1J0VJ17
names: Subcellular Location Annotation
messages: Membrane

1897729:BOX17 RS03135
gene id: 1897729:BOX17_RS03135
uniprot id: A0A1J0VDE5
names: Similarity
messages: Belongs to the UPF0234 family.

1897729:BOX17 RS08955
gene id: 1897729:BOX17_RS08955
uniprot id: A0A1J0VGA7
names: Similarity
messages: Belongs to the glycosyl hydrolase 30 family.

1897729:BOX17 RS00265
gene id: 1897729:BOX17_RS00265
uniprot id: A0A1J0VBV2
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

1897729:BOX17 RS04960
gene id: 1897729:BOX17_RS04960
uniprot id: A0A1J0VEA0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

1897729:BOX17 RS08400
gene id: 1897729:BOX17_RS08400
uniprot id: A0A1J0VG15
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

1897729:BOX17 RS03035
gene id: 1897729:BOX17_RS03035
uniprot id: A0A1J0VDF1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

1897729:BOX17 RS04895
gene id: 1897729:BOX17_RS04895
uniprot id: A0A1J0VE93
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1897729:BOX17 RS14930
gene id: 1897729:BOX17_RS14930
uniprot id: A0A1J0VJB1
names: Function
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. Fucose synthase subfamily.
messages: Catalyzes the two-step NADP-dependent conversion of GDP-4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction.

1897729:BOX17 RS14055
gene id: 1897729:BOX17_RS14055
uniprot id: A0A1J0VIU0
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LipB family.
messages: Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
messages: Cytoplasm
messages: In the reaction, the free carboxyl group of octanoic acid is attached via an amide linkage to the epsilon-amino group of a specific lysine residue of lipoyl domains of lipoate-dependent enzymes.

1897729:BOX17 RS12795
gene id: 1897729:BOX17_RS12795
uniprot id: A0A1J0VI86
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0283 family.
messages: Cell inner membrane
messages: Membrane

1897729:BOX17 RS04910
gene id: 1897729:BOX17_RS04910
uniprot id: A0A1J0VE92
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1897729:BOX17 RS07700
gene id: 1897729:BOX17_RS07700
uniprot id: A0A1J0VFM9
names: Function
names: Similarity
messages: Belongs to the helicase family. RecG subfamily.
messages: Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA).

1897729:BOX17 RS02530
gene id: 1897729:BOX17_RS02530
uniprot id: A0A1J0VD20
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

1897729:BOX17 RS11910
gene id: 1897729:BOX17_RS11910
uniprot id: A0A1J0VHR8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1897729:BOX17 RS14815
gene id: 1897729:BOX17_RS14815
uniprot id: A0A1J0VJ87
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inositol monophosphatase superfamily. CysQ family.
messages: Cell inner membrane
messages: Converts adenosine-3',5'-bisphosphate (PAP) to AMP.

1897729:BOX17 RS13670
gene id: 1897729:BOX17_RS13670
uniprot id: A0A1J0VIP5
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1897729:BOX17 RS13230
gene id: 1897729:BOX17_RS13230
uniprot id: A0A1J0VIE3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

1897729:BOX17 RS06500
gene id: 1897729:BOX17_RS06500
uniprot id: A0A1J0VF12
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1897729:BOX17 RS08435
gene id: 1897729:BOX17_RS08435
uniprot id: A0A1J0VG34
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

1897729:BOX17 RS05730
gene id: 1897729:BOX17_RS05730
uniprot id: A0A1J0VEQ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAN1 family.
messages: Nuclease required for the repair of DNA interstrand cross-links (ICL). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions.
messages: Nucleus

1897729:BOX17 RS01080
gene id: 1897729:BOX17_RS01080
uniprot id: A0A1J0VCE8
names: Similarity
messages: Belongs to the UPF0145 family.

1897729:BOX17 RS12040
gene id: 1897729:BOX17_RS12040
uniprot id: A0A1J0VHT9
names: Similarity
messages: Belongs to the UPF0178 family.

1897729:BOX17 RS14895
gene id: 1897729:BOX17_RS14895
uniprot id: A0A1J0VJ84
names: Subcellular Location Annotation
messages: Membrane

1897729:BOX17 RS09170
gene id: 1897729:BOX17_RS09170
uniprot id: A0A1J0VGF0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

1897729:BOX17 RS08685
gene id: 1897729:BOX17_RS08685
uniprot id: A0A1J0VG83
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

1897729:BOX17 RS01785
gene id: 1897729:BOX17_RS01785
uniprot id: A0A1J0VCN9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

1897729:BOX17 RS10215
gene id: 1897729:BOX17_RS10215
uniprot id: A0A1J0VGW4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

1897729:BOX17 RS04855
gene id: 1897729:BOX17_RS04855
uniprot id: A0A1J0VE68
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1897729:BOX17 RS14375
gene id: 1897729:BOX17_RS14375
uniprot id: A0A1J0VJ10
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1897729:BOX17 RS05840
gene id: 1897729:BOX17_RS05840
uniprot id: A0A1J0VEP0
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1897729:BOX17 RS12610
gene id: 1897729:BOX17_RS12610
uniprot id: A0A1J0VI41
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Membrane

1897729:BOX17 RS10385
gene id: 1897729:BOX17_RS10385
uniprot id: A0A1J0VH00
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GcdB/MmdB/OadB family.
messages: Catalyzes the decarboxylation of oxaloacetate coupled to Na(+) translocation.
messages: Cell membrane
messages: Heterotrimer of an alpha, a beta and a gamma subunit.
messages: Membrane

1897729:BOX17 RS07855
gene id: 1897729:BOX17_RS07855
uniprot id: A0A1J0VFS8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family. T3SS ATPase subfamily.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

1897729:BOX17 RS12095
gene id: 1897729:BOX17_RS12095
uniprot id: A0A1J0VHU4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1897729:BOX17 RS03345
gene id: 1897729:BOX17_RS03345
uniprot id: A0A1J0VDF8
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase class-III family.

1897729:BOX17 RS07695
gene id: 1897729:BOX17_RS07695
uniprot id: A0A1J0VKH4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1897729:BOX17 RS14280
gene id: 1897729:BOX17_RS14280
uniprot id: A0A1J0VIX5
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1897729:BOX17 RS09300
gene id: 1897729:BOX17_RS09300
uniprot id: A0A1J0VGI1
names: Similarity
messages: Belongs to the universal stress protein A family.

1897729:BOX17 RS05375
gene id: 1897729:BOX17_RS05375
uniprot id: A0A1J0VEH6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Cell membrane
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

1897729:BOX17 RS15565
gene id: 1897729:BOX17_RS15565
uniprot id: A0A1J0VJK5
names: Similarity
messages: Belongs to the ArsC family.

1897729:BOX17 RS15880
gene id: 1897729:BOX17_RS15880
uniprot id: A0A1J0VJR2
names: Function
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
messages: Catalyzes the reversible oxidative deamination of glutamate to alpha-ketoglutarate and ammonia.

1897729:BOX17 RS12245
gene id: 1897729:BOX17_RS12245
uniprot id: A0A1J0VHY1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ThiC family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
messages: Homodimer.

1897729:BOX17 RS07935
gene id: 1897729:BOX17_RS07935
uniprot id: A0A1J0VFU6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

1897729:BOX17 RS09710
gene id: 1897729:BOX17_RS09710
uniprot id: A0A1J0VGQ1
names: Cofactor
messages: Binds 2 Mg(2+) ions per monomer.

1897729:BOX17 RS08940
gene id: 1897729:BOX17_RS08940
uniprot id: A0A1J0VGB7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1897729:BOX17 RS03200
gene id: 1897729:BOX17_RS03200
uniprot id: A0A1J0VDC6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the band 7/mec-2 family. HflK subfamily.
messages: HflC and HflK could encode or regulate a protease.
messages: HflC and HflK may interact to form a multimeric complex.
messages: Membrane

1897729:BOX17 RS00455
gene id: 1897729:BOX17_RS00455
uniprot id: A0A1J0VC08
names: Similarity
messages: Belongs to the proline racemase family.

1897729:BOX17 RS02045
gene id: 1897729:BOX17_RS02045
uniprot id: A0A1J0VK76
names: Similarity
messages: Belongs to the oxygen-dependent FAD-linked oxidoreductase family.

1897729:BOX17 RS08340
gene id: 1897729:BOX17_RS08340
uniprot id: A0A1J0VG05
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1897729:BOX17 RS01510
gene id: 1897729:BOX17_RS01510
uniprot id: A0A1J0VK73
names: Cofactor
names: Function
messages: Accepts electrons from ETF and reduces ubiquinone.
messages: Binds 1 [4Fe-4S] cluster.

1897729:BOX17 RS11585
gene id: 1897729:BOX17_RS11585
uniprot id: A0A1J0VHL6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoD/SigA subfamily.
messages: Cytoplasm
messages: Interacts transiently with the RNA polymerase catalytic core.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.

1897729:BOX17 RS00165
gene id: 1897729:BOX17_RS00165
uniprot id: A0A1J0VBW9
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1897729:BOX17 RS10270
gene id: 1897729:BOX17_RS10270
uniprot id: A0A1J0VGW9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Monomer.

1897729:BOX17 RS16135
gene id: 1897729:BOX17_RS16135
uniprot id: A0A1J0VJX8
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1897729:BOX17 RS02760
gene id: 1897729:BOX17_RS02760
uniprot id: A0A1J0VD68
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily.
messages: Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA.
messages: Cytoplasm
messages: Monomer.

1897729:BOX17 RS04690
gene id: 1897729:BOX17_RS04690
uniprot id: A0A1J0VE31
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

1897729:BOX17 RS16080
gene id: 1897729:BOX17_RS16080
uniprot id: A0A1J0VJX2
names: Similarity
messages: Belongs to the GcvT family.

1897729:BOX17 RS05780
gene id: 1897729:BOX17_RS05780
uniprot id: A0A1J0VEP8
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

1897729:BOX17 RS09550
gene id: 1897729:BOX17_RS09550
uniprot id: A0A1J0VGM8
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1897729:BOX17 RS03595
gene id: 1897729:BOX17_RS03595
uniprot id: A0A1J0VDJ8
names: Caution
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the thiamine-monophosphate kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate.

1897729:BOX17 RS02465
gene id: 1897729:BOX17_RS02465
uniprot id: A0A1J0VD23
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Catalyzes the sodium-dependent uptake of extracellular L-proline.
messages: Cell inner membrane
messages: Membrane

1897729:BOX17 RS03185
gene id: 1897729:BOX17_RS03185
uniprot id: A0A1J0VDE4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

1897729:BOX17 RS11915
gene id: 1897729:BOX17_RS11915
uniprot id: A0A1J0VHT1
names: Subcellular Location Annotation
messages: Membrane

1897729:BOX17 RS05665
gene id: 1897729:BOX17_RS05665
uniprot id: A0A1J0VEK9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LysR transcriptional regulatory family.
messages: Cytoplasm

1897729:BOX17 RS01625
gene id: 1897729:BOX17_RS01625
uniprot id: A0A1J0VCN4
names: Similarity
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.

1897729:BOX17 RS05220
gene id: 1897729:BOX17_RS05220
uniprot id: A0A1J0VED0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NhaD Na(+)/H(+) (TC 2.A.62) antiporter family.
messages: Membrane

1897729:BOX17 RS06900
gene id: 1897729:BOX17_RS06900
uniprot id: A0A1J0VF88
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1897729:BOX17 RS10535
gene id: 1897729:BOX17_RS10535
uniprot id: A0A1J0VH16
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
messages: Membrane

1897729:BOX17 RS08785
gene id: 1897729:BOX17_RS08785
uniprot id: A0A1J0VG64
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. GluQ subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5-dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon.

1897729:BOX17 RS05130
gene id: 1897729:BOX17_RS05130
uniprot id: A0A1J0VED3
names: Similarity
messages: Belongs to the flavin oxidoreductase frp family.

1897729:BOX17 RS00480
gene id: 1897729:BOX17_RS00480
uniprot id: A0A1J0VC21
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

1897729:BOX17 RS14760
gene id: 1897729:BOX17_RS14760
uniprot id: A0A1J0VJ59
names: Subcellular Location Annotation
messages: Membrane

1897729:BOX17 RS15830
gene id: 1897729:BOX17_RS15830
uniprot id: A0A1J0VJS2
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvB family.
messages: Cytoplasm
messages: Has 3 domains, the large (RuvB-L) and small ATPase (RuvB-S) domains and the C-terminal head (RuvB-H) domain. The head domain binds DNA, while the ATPase domains jointly bind ATP, ADP or are empty depending on the state of the subunit in the translocation cycle. During a single DNA translocation step the structure of each domain remains the same, but their relative positions change.
messages: Homohexamer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time. Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange. Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration. The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration. Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.

1897729:BOX17 RS15340
gene id: 1897729:BOX17_RS15340
uniprot id: A0A1J0VJI2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1897729:BOX17 RS07470
gene id: 1897729:BOX17_RS07470
uniprot id: A0A1J0VFI3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1897729:BOX17 RS10865
gene id: 1897729:BOX17_RS10865
uniprot id: A0A1J0VH82
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

1897729:BOX17 RS15700
gene id: 1897729:BOX17_RS15700
uniprot id: A0A1J0VJP8
names: Function
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

1897729:BOX17 RS09555
gene id: 1897729:BOX17_RS09555
uniprot id: A0A1J0VGK0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

1897729:BOX17 RS04635
gene id: 1897729:BOX17_RS04635
uniprot id: A0A1J0VE52
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1897729:BOX17 RS02245
gene id: 1897729:BOX17_RS02245
uniprot id: A0A1J0VCY0
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

1897729:BOX17 RS15845
gene id: 1897729:BOX17_RS15845
uniprot id: A0A1J0VJS8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

1897729:BOX17 RS09705
gene id: 1897729:BOX17_RS09705
uniprot id: A0A1J0VGN4
names: Function
names: Similarity
messages: Belongs to the MinE family.
messages: Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.

1897729:BOX17 RS06605
gene id: 1897729:BOX17_RS06605
uniprot id: A0A1J0VF37
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glutamine synthetase family.
messages: Cytoplasm
messages: Oligomer of 12 subunits arranged in the form of two hexagons.

1897729:BOX17 RS13015
gene id: 1897729:BOX17_RS13015
uniprot id: A0A1J0VIC9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RlmKL family.
messages: Cytoplasm
messages: Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA.

1897729:BOX17 RS06105
gene id: 1897729:BOX17_RS06105
uniprot id: A0A1J0VEV1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

1897729:BOX17 RS02950
gene id: 1897729:BOX17_RS02950
uniprot id: A0A1J0VD87
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methylthiotransferase family. MiaB subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
messages: Cytoplasm
messages: Monomer.

1897729:BOX17 RS01860
gene id: 1897729:BOX17_RS01860
uniprot id: A0A1J0VCQ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZapG family.
messages: Cell inner membrane
messages: Membrane

1897729:BOX17 RS10375
gene id: 1897729:BOX17_RS10375
uniprot id: A0A1J0VH11
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OadG family.
messages: Catalyzes the decarboxylation of oxaloacetate coupled to Na(+) translocation.
messages: Cell membrane
messages: Heterotrimer of an alpha, a beta and a gamma subunit.
messages: Membrane

1897729:BOX17 RS05700
gene id: 1897729:BOX17_RS05700
uniprot id: A0A1J0VEQ1
names: Similarity
messages: Belongs to the shaker potassium channel beta subunit family.

1897729:BOX17 RS12190
gene id: 1897729:BOX17_RS12190
uniprot id: A0A1J0VHZ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family.
messages: Membrane

1897729:BOX17 RS05470
gene id: 1897729:BOX17_RS05470
uniprot id: A0A1J0VEJ0
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

1897729:BOX17 RS07725
gene id: 1897729:BOX17_RS07725
uniprot id: A0A1J0VFN2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family.
messages: Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate.
messages: Cell inner membrane

1897729:BOX17 RS07860
gene id: 1897729:BOX17_RS07860
uniprot id: A0A1J0VFQ4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

1897729:BOX17 RS06080
gene id: 1897729:BOX17_RS06080
uniprot id: A0A1J0VES9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

1897729:BOX17 RS09315
gene id: 1897729:BOX17_RS09315
uniprot id: A0A1J0VGJ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell inner membrane
messages: Membrane

1897729:BOX17 RS07875
gene id: 1897729:BOX17_RS07875
uniprot id: A0A1J0VFS0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0). The b'-subunit is a diverged and duplicated form of b found in plants and photosynthetic bacteria.
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

1897729:BOX17 RS07245
gene id: 1897729:BOX17_RS07245
uniprot id: A0A1J0VFF0
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase class-2 family.
messages: Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.

1897729:BOX17 RS03020
gene id: 1897729:BOX17_RS03020
uniprot id: A0A1J0VKA3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

1897729:BOX17 RS14245
gene id: 1897729:BOX17_RS14245
uniprot id: A0A1J0VIZ1
names: Similarity
messages: Belongs to the TrpF family.

1897729:BOX17 RS12805
gene id: 1897729:BOX17_RS12805
uniprot id: A0A1J0VI71
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1897729:BOX17 RS08860
gene id: 1897729:BOX17_RS08860
uniprot id: A0A1J0VGB2
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

1897729:BOX17 RS03760
gene id: 1897729:BOX17_RS03760
uniprot id: A0A1J0VDT9
names: Subcellular Location Annotation
messages: Membrane

1897729:BOX17 RS00155
gene id: 1897729:BOX17_RS00155
uniprot id: A0A1J0VBW1
names: Function
names: Similarity
messages: Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PSRP subfamily.
messages: Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation/dephosphorylation.

1897729:BOX17 RS01350
gene id: 1897729:BOX17_RS01350
uniprot id: A0A1J0VCH5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

1897729:BOX17 RS10245
gene id: 1897729:BOX17_RS10245
uniprot id: A0A1J0VGZ1
names: Similarity
messages: Belongs to the heat shock protein 70 family.

1897729:BOX17 RS03295
gene id: 1897729:BOX17_RS03295
uniprot id: A0A1J0VDE9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 1 subfamily.
messages: Cell membrane
messages: Heterotetramer composed of ParC and ParE.
messages: Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.

1897729:BOX17 RS05790
gene id: 1897729:BOX17_RS05790
uniprot id: A0A1J0VER7
names: Similarity
messages: Belongs to the agmatine deiminase family.

1897729:BOX17 RS15185
gene id: 1897729:BOX17_RS15185
uniprot id: A0A1J0VJF2
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1897729:BOX17 RS11855
gene id: 1897729:BOX17_RS11855
uniprot id: A0A1J0VHS1
names: Similarity
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.

1897729:BOX17 RS17220
gene id: 1897729:BOX17_RS17220
uniprot id: A0A1J0VD78
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1897729:BOX17 RS07670
gene id: 1897729:BOX17_RS07670
uniprot id: A0A1J0VFL3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1897729:BOX17 RS10485
gene id: 1897729:BOX17_RS10485
uniprot id: A0A1J0VH18
names: Similarity
messages: Belongs to the gamma-BBH/TMLD family.

1897729:BOX17 RS03250
gene id: 1897729:BOX17_RS03250
uniprot id: A0A1J0VDJ4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

1897729:BOX17 RS03220
gene id: 1897729:BOX17_RS03220
uniprot id: A0A1J0VDC9
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

1897729:BOX17 RS02230
gene id: 1897729:BOX17_RS02230
uniprot id: A0A1J0VCW8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

1897729:BOX17 RS01615
gene id: 1897729:BOX17_RS01615
uniprot id: A0A1J0VCK9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase E/G family. RNase E subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per homotetramer.
messages: Cell inner membrane
messages: Component of the RNA degradosome, which is a multiprotein complex involved in RNA processing and mRNA degradation. Within the RNA degradosome, RNase E assembles into a homotetramer formed by a dimer of dimers.
messages: Cytoplasm
messages: Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs.

1897729:BOX17 RS16390
gene id: 1897729:BOX17_RS16390
uniprot id: A0A1J0VK15
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1897729:BOX17 RS16440
gene id: 1897729:BOX17_RS16440
uniprot id: A0A1J0VK22
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

1897729:BOX17 RS14080
gene id: 1897729:BOX17_RS14080
uniprot id: A0A1J0VIW6
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

1897729:BOX17 RS10045
gene id: 1897729:BOX17_RS10045
uniprot id: A0A1J0VKJ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

1897729:BOX17 RS09275
gene id: 1897729:BOX17_RS09275
uniprot id: A0A1J0VGE9
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. SDR39U1 subfamily.

1897729:BOX17 RS00255
gene id: 1897729:BOX17_RS00255
uniprot id: A0A1J0VBW6
names: Function
names: Subcellular Location Annotation
messages: Catalyzes the Claisen rearrangement of chorismate to prephenate and the decarboxylation/dehydration of prephenate to phenylpyruvate.
messages: Cytoplasm

1897729:BOX17 RS14770
gene id: 1897729:BOX17_RS14770
uniprot id: A0A1J0VJ83
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

1897729:BOX17 RS09735
gene id: 1897729:BOX17_RS09735
uniprot id: A0A1J0VGP5
names: Subcellular Location Annotation
messages: Membrane

1897729:BOX17 RS01950
gene id: 1897729:BOX17_RS01950
uniprot id: A0A1J0VCS1
names: Function
names: Similarity
messages: Belongs to the sigma-54 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

1897729:BOX17 RS10690
gene id: 1897729:BOX17_RS10690
uniprot id: A0A1J0VH71
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1897729:BOX17 RS03800
gene id: 1897729:BOX17_RS03800
uniprot id: A0A1J0VDU3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.
messages: Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.
messages: Cytoplasm
messages: Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).
messages: The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.
messages: The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1.

1897729:BOX17 RS11965
gene id: 1897729:BOX17_RS11965
uniprot id: A0A1J0VHS0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

1897729:BOX17 RS13945
gene id: 1897729:BOX17_RS13945
uniprot id: A0A1J0VIT5
names: Function
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

1897729:BOX17 RS10205
gene id: 1897729:BOX17_RS10205
uniprot id: A0A1J0VGX0
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: Allosterically activated by HslU binding.
messages: Belongs to the peptidase T1B family. HslV subfamily.
messages: Cytoplasm
messages: Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.

1897729:BOX17 RS14640
gene id: 1897729:BOX17_RS14640
uniprot id: A0A1J0VJ48
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
messages: Allosterically activated by GTP.
messages: Belongs to the UPRTase family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.
messages: Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.

1897729:BOX17 RS13590
gene id: 1897729:BOX17_RS13590
uniprot id: A0A1J0VIK7
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

1897729:BOX17 RS07825
gene id: 1897729:BOX17_RS07825
uniprot id: A0A1J0VFQ5
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

1897729:BOX17 RS06205
gene id: 1897729:BOX17_RS06205
uniprot id: A0A1J0VEV5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

1897729:BOX17 RS04850
gene id: 1897729:BOX17_RS04850
uniprot id: A0A1J0VE95
names: Subcellular Location Annotation
messages: Membrane

1897729:BOX17 RS03190
gene id: 1897729:BOX17_RS03190
uniprot id: A0A1J0VDE0
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. HisZ subfamily.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine.
messages: This function is generally fulfilled by the C-terminal part of HisG, which is missing in some bacteria such as this one.

1897729:BOX17 RS08525
gene id: 1897729:BOX17_RS08525
uniprot id: A0A1J0VG50
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fluoride channel Fluc/FEX (TC 1.A.43) family.
messages: Cell membrane
messages: Fluoride-specific ion channel. Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane
messages: Na(+) is not transported, but it plays an essential structural role and its presence is essential for fluoride channel function.

1897729:BOX17 RS00415
gene id: 1897729:BOX17_RS00415
uniprot id: A0A1J0VC02
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase T family.
messages: Binds two Mg(2+) per subunit. The active form of the enzyme binds two Mg(2+) ions in its active site. The first Mg(2+) forms only one salt bridge with the protein.
messages: Homodimer.
messages: Trims short 3' overhangs of a variety of RNA species, leaving a one or two nucleotide 3' overhang. Responsible for the end-turnover of tRNA: specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis.

1897729:BOX17 RS07485
gene id: 1897729:BOX17_RS07485
uniprot id: A0A1J0VFI0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

1897729:BOX17 RS11130
gene id: 1897729:BOX17_RS11130
uniprot id: A0A1J0VHD4
names: Function
messages: Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).

1897729:BOX17 RS11640
gene id: 1897729:BOX17_RS11640
uniprot id: A0A1J0VHL5
names: Function
names: Similarity
messages: Belongs to the esterase D family.
messages: Serine hydrolase involved in the detoxification of formaldehyde.

1897729:BOX17 RS12385
gene id: 1897729:BOX17_RS12385
uniprot id: A0A1J0VI16
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbsD / FucU family. RbsD subfamily.
messages: Catalyzes the interconversion of beta-pyran and beta-furan forms of D-ribose.
messages: Cytoplasm
messages: Homodecamer.

1897729:BOX17 RS15765
gene id: 1897729:BOX17_RS15765
uniprot id: A0A1J0VJR0
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

1897729:BOX17 RS08325
gene id: 1897729:BOX17_RS08325
uniprot id: A0A1J0VFY1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the malate synthase family. GlcB subfamily.
messages: Cytoplasm
messages: Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1897729:BOX17 RS11360
gene id: 1897729:BOX17_RS11360
uniprot id: A0A1J0VHF7
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with bS18 to 16S ribosomal RNA.

1897729:BOX17 RS02215
gene id: 1897729:BOX17_RS02215
uniprot id: A0A1J0VCX3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LolB family.
messages: Cell outer membrane
messages: Membrane
messages: Monomer.
messages: Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein.

1897729:BOX17 RS03210
gene id: 1897729:BOX17_RS03210
uniprot id: A0A1J0VDI6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Hfq family.
messages: Homohexamer.
messages: RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs.

1897729:BOX17 RS14160
gene id: 1897729:BOX17_RS14160
uniprot id: A0A1J0VIY5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrF family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Cell membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway.

1897729:BOX17 RS01320
gene id: 1897729:BOX17_RS01320
uniprot id: A0A1J0VCH9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DEAD box helicase family. RhlB subfamily.
messages: Component of the RNA degradosome, which is a multiprotein complex involved in RNA processing and mRNA degradation.
messages: Cytoplasm
messages: DEAD-box RNA helicase involved in RNA degradation. Has RNA-dependent ATPase activity and unwinds double-stranded RNA.

1897729:BOX17 RS13445
gene id: 1897729:BOX17_RS13445
uniprot id: A0A1J0VIK2
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit A family.

1897729:BOX17 RS05685
gene id: 1897729:BOX17_RS05685
uniprot id: A0A1J0VEN1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.
messages: Binds 2 iron ions per subunit.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

1897729:BOX17 RS10350
gene id: 1897729:BOX17_RS10350
uniprot id: A0A1J0VGY5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Mediates global changes in gene expression, shifting from rapid growth to stress survival by linking envelope stress, the stringent response and the catabolite repression systems. Usually binds in the 5'-UTR; binding at or near the Shine-Dalgarno sequence prevents ribosome-binding, repressing translation, binding elsewhere in the 5'-UTR can activate translation and/or stabilize the mRNA. Its function is antagonized by small RNA(s).
messages: Belongs to the CsrA/RsmA family.
messages: Cytoplasm
messages: Homodimer; the beta-strands of each monomer intercalate to form a hydrophobic core, while the alpha-helices form wings that extend away from the core.

1897729:BOX17 RS08370
gene id: 1897729:BOX17_RS08370
uniprot id: A0A1J0VKK3
names: Similarity
messages: Belongs to the universal stress protein A family.

1897729:BOX17 RS10000
gene id: 1897729:BOX17_RS10000
uniprot id: A0A1J0VGU9
names: Similarity
messages: Belongs to the ArsC family.

1897729:BOX17 RS02255
gene id: 1897729:BOX17_RS02255
uniprot id: A0A1J0VCY4
names: Similarity
messages: Belongs to the peptidase M18 family.

1897729:BOX17 RS02685
gene id: 1897729:BOX17_RS02685
uniprot id: A0A1J0VD93
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.
messages: In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family.

1897729:BOX17 RS05515
gene id: 1897729:BOX17_RS05515
uniprot id: A0A1J0VEJ8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Cytoplasm
messages: Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.

1897729:BOX17 RS14635
gene id: 1897729:BOX17_RS14635
uniprot id: A0A1J0VJ58
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
messages: Cytoplasm
messages: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.

1897729:BOX17 RS01315
gene id: 1897729:BOX17_RS01315
uniprot id: A0A1J0VCF4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the helicase family. DinG subfamily. Type 1 sub-subfamily.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA-dependent ATPase and 5'-3' DNA helicase.

1897729:BOX17 RS03650
gene id: 1897729:BOX17_RS03650
uniprot id: A0A1J0VDM7
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1897729:BOX17 RS05110
gene id: 1897729:BOX17_RS05110
uniprot id: A0A1J0VEC7
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.

1897729:BOX17 RS04510
gene id: 1897729:BOX17_RS04510
uniprot id: A0A1J0VE26
names: Similarity
names: Subunit
messages: Belongs to the threonine aldolase family.
messages: Homotetramer.

1897729:BOX17 RS05625
gene id: 1897729:BOX17_RS05625
uniprot id: A0A1J0VEK1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

1897729:BOX17 RS01210
gene id: 1897729:BOX17_RS01210
uniprot id: A0A1J0VCD7
names: Similarity
messages: Belongs to the type IA topoisomerase family.

1897729:BOX17 RS04915
gene id: 1897729:BOX17_RS04915
uniprot id: A0A1J0VED7
names: Caution
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the peroxidase family. Peroxidase/catalase subfamily.
messages: Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per dimer.
messages: Formation of the three residue Trp-Tyr-Met cross-link is important for the catalase, but not the peroxidase activity of the enzyme.
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1897729:BOX17 RS01715
gene id: 1897729:BOX17_RS01715
uniprot id: A0A1J0VCL6
names: Function
names: Similarity
messages: Belongs to the LpxC family.
messages: Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.

1897729:BOX17 RS13970
gene id: 1897729:BOX17_RS13970
uniprot id: A0A1J0VIR8
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphofructokinase type A (PFKA) family. PPi-dependent PFK group II subfamily. Clade 'B2' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Non-allosteric.

1897729:BOX17 RS04725
gene id: 1897729:BOX17_RS04725
uniprot id: A0A1J0VE62
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

1897729:BOX17 RS01985
gene id: 1897729:BOX17_RS01985
uniprot id: A0A1J0VCU0
names: Similarity
messages: Belongs to the peptidase U62 family.

1897729:BOX17 RS04175
gene id: 1897729:BOX17_RS04175
uniprot id: A0A1J0VE06
names: Function
names: PTM
names: Similarity
messages: Belongs to the NAPRTase family.
messages: Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate.
messages: Transiently phosphorylated on a His residue during the reaction cycle. Phosphorylation strongly increases the affinity for substrates and increases the rate of nicotinate D-ribonucleotide production. Dephosphorylation regenerates the low-affinity form of the enzyme, leading to product release.

1897729:BOX17 RS08845
gene id: 1897729:BOX17_RS08845
uniprot id: A0A1J0VGA1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AB hydrolase superfamily. MetX family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine.

1897729:BOX17 RS07890
gene id: 1897729:BOX17_RS07890
uniprot id: A0A1J0VFP6
names: Subcellular Location Annotation
messages: Membrane

1897729:BOX17 RS04240
gene id: 1897729:BOX17_RS04240
uniprot id: A0A1J0VDY1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1897729:BOX17 RS02890
gene id: 1897729:BOX17_RS02890
uniprot id: A0A1J0VDB5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1897729:BOX17 RS16060
gene id: 1897729:BOX17_RS16060
uniprot id: A0A1J0VJW6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1897729:BOX17 RS06345
gene id: 1897729:BOX17_RS06345
uniprot id: A0A1J0VEY5
names: Subcellular Location Annotation
messages: Membrane

1897729:BOX17 RS06495
gene id: 1897729:BOX17_RS06495
uniprot id: A0A1J0VF32
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

1897729:BOX17 RS00995
gene id: 1897729:BOX17_RS00995
uniprot id: A0A1J0VC99
names: Similarity
messages: Belongs to the Gfa family.

1897729:BOX17 RS05360
gene id: 1897729:BOX17_RS05360
uniprot id: A0A1J0VEH2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

1897729:BOX17 RS06670
gene id: 1897729:BOX17_RS06670
uniprot id: A0A1J0VF49
names: Similarity
messages: Belongs to the DNase I family.

1897729:BOX17 RS11820
gene id: 1897729:BOX17_RS11820
uniprot id: A0A1J0VHQ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1897729:BOX17 RS11515
gene id: 1897729:BOX17_RS11515
uniprot id: A0A1J0VHL0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptD family.
messages: Cell outer membrane
messages: Component of the lipopolysaccharide transport and assembly complex. Interacts with LptE and LptA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane.

1897729:BOX17 RS15320
gene id: 1897729:BOX17_RS15320
uniprot id: A0A1J0VJH7
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

1897729:BOX17 RS08560
gene id: 1897729:BOX17_RS08560
uniprot id: A0A1J0VG21
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. NspC subfamily.
messages: Catalyzes the decarboxylation of carboxynorspermidine and carboxyspermidine.
messages: Cytoplasm
messages: Homodimer.

1897729:BOX17 RS08295
gene id: 1897729:BOX17_RS08295
uniprot id: A0A1J0VFZ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

1897729:BOX17 RS14030
gene id: 1897729:BOX17_RS14030
uniprot id: A0A1J0VIV0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEDS family. MrdB/RodA subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Peptidoglycan polymerase that is essential for cell wall elongation.

1897729:BOX17 RS10225
gene id: 1897729:BOX17_RS10225
uniprot id: A0A1J0VKM6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

1897729:BOX17 RS15915
gene id: 1897729:BOX17_RS15915
uniprot id: A0A1J0VJT6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

1897729:BOX17 RS15155
gene id: 1897729:BOX17_RS15155
uniprot id: A0A1J0VJE5
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

1897729:BOX17 RS09045
gene id: 1897729:BOX17_RS09045
uniprot id: A0A1J0VGC5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

1897729:BOX17 RS10945
gene id: 1897729:BOX17_RS10945
uniprot id: A0A1J0VH97
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

1897729:BOX17 RS12890
gene id: 1897729:BOX17_RS12890
uniprot id: A0A1J0VIB8
names: Cofactor
messages: Can also use Mn(2+) ion.

1897729:BOX17 RS05985
gene id: 1897729:BOX17_RS05985
uniprot id: A0A1J0VEU6
names: Subcellular Location Annotation
messages: Membrane

1897729:BOX17 RS04465
gene id: 1897729:BOX17_RS04465
uniprot id: A0A1J0VE20
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily.
messages: Catalyzes the hydrolysis of 5-hydroxyisourate (HIU) to 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU).
messages: Homotetramer.

1897729:BOX17 RS00835
gene id: 1897729:BOX17_RS00835
uniprot id: A0A1J0VC90
names: Similarity
messages: Belongs to the YciI family.

1897729:BOX17 RS12865
gene id: 1897729:BOX17_RS12865
uniprot id: A0A1J0VI91
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.

1897729:BOX17 RS03445
gene id: 1897729:BOX17_RS03445
uniprot id: A0A1J0VKB2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm

1897729:BOX17 RS08920
gene id: 1897729:BOX17_RS08920
uniprot id: A0A1J0VG96
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the porin LamB (TC 1.B.3) family.
messages: Membrane

1897729:BOX17 RS01235
gene id: 1897729:BOX17_RS01235
uniprot id: A0A1J0VCD5
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

1897729:BOX17 RS16510
gene id: 1897729:BOX17_RS16510
uniprot id: A0A1J0VK33
names: Subcellular Location Annotation
messages: Membrane

1897729:BOX17 RS10065
gene id: 1897729:BOX17_RS10065
uniprot id: A0A1J0VGV3
names: Similarity
messages: Belongs to the Skp family.

1897729:BOX17 RS05175
gene id: 1897729:BOX17_RS05175
uniprot id: A0A1J0VEC0
names: Subcellular Location Annotation
messages: Membrane

1897729:BOX17 RS07895
gene id: 1897729:BOX17_RS07895
uniprot id: A0A1J0VFT8
names: Function
names: Similarity
messages: Belongs to the ParB family.
messages: Involved in chromosome partition. Localize to both poles of the predivisional cell following completion of DNA replication. Binds to the DNA origin of replication.

1897729:BOX17 RS07770
gene id: 1897729:BOX17_RS07770
uniprot id: A0A1J0VFR3
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

1897729:BOX17 RS15230
gene id: 1897729:BOX17_RS15230
uniprot id: A0A1J0VJE1
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

1897729:BOX17 RS16385
gene id: 1897729:BOX17_RS16385
uniprot id: A0A1J0VK20
names: Similarity
messages: Belongs to the iron/ascorbate-dependent oxidoreductase family.

1897729:BOX17 RS14265
gene id: 1897729:BOX17_RS14265
uniprot id: A0A1J0VIZ2
names: Similarity
messages: Belongs to the folylpolyglutamate synthase family.

1897729:BOX17 RS01925
gene id: 1897729:BOX17_RS01925
uniprot id: A0A1J0VCQ7
names: Similarity
messages: Belongs to the SIS family. GutQ/KpsF subfamily.

1897729:BOX17 RS00590
gene id: 1897729:BOX17_RS00590
uniprot id: A0A1J0VC47
names: Similarity
messages: Belongs to the histone deacetylase family.

1897729:BOX17 RS10610
gene id: 1897729:BOX17_RS10610
uniprot id: A0A1J0VH56
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.

1897729:BOX17 RS10560
gene id: 1897729:BOX17_RS10560
uniprot id: A0A1J0VH33
names: Similarity
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
messages: Belongs to the peroxiredoxin family. Prx6 subfamily.

1897729:BOX17 RS12540
gene id: 1897729:BOX17_RS12540
uniprot id: A0A1J0VI53
names: Function
names: Similarity
messages: Belongs to the cyanase family.
messages: Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide.

1897729:BOX17 RS13105
gene id: 1897729:BOX17_RS13105
uniprot id: A0A1J0VIF5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family. QueF type 2 subfamily.
messages: Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
messages: Cytoplasm
messages: Homodimer.

1897729:BOX17 RS04735
gene id: 1897729:BOX17_RS04735
uniprot id: A0A1J0VE39
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.

1897729:BOX17 RS05450
gene id: 1897729:BOX17_RS05450
uniprot id: A0A1J0VEG9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamB family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

1897729:BOX17 RS08310
gene id: 1897729:BOX17_RS08310
uniprot id: A0A1J0VG25
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

1897729:BOX17 RS05815
gene id: 1897729:BOX17_RS05815
uniprot id: A0A1J0VEN7
names: Similarity
messages: Belongs to the universal stress protein A family.

1897729:BOX17 RS10025
gene id: 1897729:BOX17_RS10025
uniprot id: A0A1J0VGV8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

1897729:BOX17 RS06990
gene id: 1897729:BOX17_RS06990
uniprot id: A0A1J0VFA4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1897729:BOX17 RS13940
gene id: 1897729:BOX17_RS13940
uniprot id: A0A1J0VIT9
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

1897729:BOX17 RS12950
gene id: 1897729:BOX17_RS12950
uniprot id: A0A1J0VIB2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

1897729:BOX17 RS12285
gene id: 1897729:BOX17_RS12285
uniprot id: A0A1J0VHY7
names: Subcellular Location Annotation
messages: Membrane

1897729:BOX17 RS08075
gene id: 1897729:BOX17_RS08075
uniprot id: A0A1J0VFV4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. KdkA/RfaP family.
messages: Catalyzes the ATP-dependent phosphorylation of the 3-deoxy-D-manno-octulosonic acid (Kdo) residue in Kdo-lipid IV(A) at the 4-OH position.
messages: Cell inner membrane
messages: Membrane

1897729:BOX17 RS14185
gene id: 1897729:BOX17_RS14185
uniprot id: A0A1J0VIX9
names: Similarity
messages: Belongs to the DNA polymerase HolA subunit family.

1897729:BOX17 RS07735
gene id: 1897729:BOX17_RS07735
uniprot id: A0A1J0VFM8
names: Function
messages: Member of the two-component regulatory system PhoR/PhoB involved in the phosphate regulon genes expression. PhoR may function as a membrane-associated protein kinase that phosphorylates PhoB in response to environmental signals.

1897729:BOX17 RS09470
gene id: 1897729:BOX17_RS09470
uniprot id: A0A1J0VGK2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OmpP1/FadL family.
messages: Cell outer membrane
messages: Membrane

1897729:BOX17 RS15745
gene id: 1897729:BOX17_RS15745
uniprot id: A0A1J0VJQ1
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

1897729:BOX17 RS00245
gene id: 1897729:BOX17_RS00245
uniprot id: A0A1J0VBX9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

1897729:BOX17 RS12355
gene id: 1897729:BOX17_RS12355
uniprot id: A0A1J0VHZ0
names: Subcellular Location Annotation
messages: Membrane

1897729:BOX17 RS05250
gene id: 1897729:BOX17_RS05250
uniprot id: A0A1J0VEJ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0126 family.
messages: Membrane

1897729:BOX17 RS14885
gene id: 1897729:BOX17_RS14885
uniprot id: A0A1J0VJA6
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

1897729:BOX17 RS11175
gene id: 1897729:BOX17_RS11175
uniprot id: A0A1J0VHD7
names: Caution
names: Function
names: PTM
names: Similarity
messages: Acetylated. Deacetylation by the SIR2-homolog deacetylase activates the enzyme.
messages: Belongs to the ATP-dependent AMP-binding enzyme family.
messages: Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1897729:BOX17 RS13700
gene id: 1897729:BOX17_RS13700
uniprot id: A0A1J0VIL7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OadG family.
messages: Catalyzes the decarboxylation of oxaloacetate coupled to Na(+) translocation.
messages: Cell membrane
messages: Heterotrimer of an alpha, a beta and a gamma subunit.
messages: Membrane

1897729:BOX17 RS08675
gene id: 1897729:BOX17_RS08675
uniprot id: A0A1J0VG61
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1897729:BOX17 RS04955
gene id: 1897729:BOX17_RS04955
uniprot id: A0A1J0VE83
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

1897729:BOX17 RS08025
gene id: 1897729:BOX17_RS08025
uniprot id: A0A1J0VFU4
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Binds two Mg(2+) per subunit. The magnesium ions form salt bridges with both the protein and the DNA. Can also accept other divalent metal cations, such as Mn(2+) or Ca(2+).
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

1897729:BOX17 RS08475
gene id: 1897729:BOX17_RS08475
uniprot id: A0A1J0VG42
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.

1897729:BOX17 RS00120
gene id: 1897729:BOX17_RS00120
uniprot id: A0A1J0VBU2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class II aldolase/RraA-like family.
messages: Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2-oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions.
messages: Homotrimer.

1897729:BOX17 RS09140
gene id: 1897729:BOX17_RS09140
uniprot id: A0A1J0VGD8
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

1897729:BOX17 RS15105
gene id: 1897729:BOX17_RS15105
uniprot id: A0A1J0VJC9
names: Function
names: Similarity
messages: Belongs to the PNP/UDP phosphorylase family. MtnN subfamily.
messages: Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively. Also cleaves 5'-deoxyadenosine, a toxic by-product of radical S-adenosylmethionine (SAM) enzymes, into 5-deoxyribose and adenine.

1897729:BOX17 RS10290
gene id: 1897729:BOX17_RS10290
uniprot id: A0A1J0VGY4
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1897729:BOX17 RS10875
gene id: 1897729:BOX17_RS10875
uniprot id: A0A1J0VH72
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta chain.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).

1897729:BOX17 RS03320
gene id: 1897729:BOX17_RS03320
uniprot id: A0A1J0VDG9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. CmoB family.
messages: Catalyzes carboxymethyl transfer from carboxy-S-adenosyl-L-methionine (Cx-SAM) to 5-hydroxyuridine (ho5U) to form 5-carboxymethoxyuridine (cmo5U) at position 34 in tRNAs.
messages: Homotetramer.

1897729:BOX17 RS03950
gene id: 1897729:BOX17_RS03950
uniprot id: A0A1J0VDQ8
names: Similarity
messages: Belongs to the phosphate/phosphite/phosphonate binding protein family.

1897729:BOX17 RS11645
gene id: 1897729:BOX17_RS11645
uniprot id: A0A1J0VHN6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 51 family.
messages: Cell inner membrane
messages: Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors.

1897729:BOX17 RS03005
gene id: 1897729:BOX17_RS03005
uniprot id: A0A1J0VDB9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1897729:BOX17 RS04660
gene id: 1897729:BOX17_RS04660
uniprot id: A0A1J0VE94
names: Similarity
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.

1897729:BOX17 RS14515
gene id: 1897729:BOX17_RS14515
uniprot id: A0A1J0VJ13
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

1897729:BOX17 RS11680
gene id: 1897729:BOX17_RS11680
uniprot id: A0A1J0VHM7
names: Subcellular Location Annotation
messages: Membrane

1897729:BOX17 RS11355
gene id: 1897729:BOX17_RS11355
uniprot id: A0A1J0VHF8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. RlmB subfamily.
messages: Cytoplasm
messages: Specifically methylates the ribose of guanosine 2251 in 23S rRNA.

1897729:BOX17 RS01910
gene id: 1897729:BOX17_RS01910
uniprot id: A0A1J0VCR3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MlaE permease family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the ABC transporter complex MlaFEDB, which is involved in a phospholipid transport pathway that maintains lipid asymmetry in the outer membrane by retrograde trafficking of phospholipids from the outer membrane to the inner membrane. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (MlaF), two transmembrane proteins (MlaE), two cytoplasmic solute-binding proteins (MlaB) and six periplasmic solute-binding proteins (MlaD).

1897729:BOX17 RS08550
gene id: 1897729:BOX17_RS08550
uniprot id: A0A1J0VG59
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1897729:BOX17 RS04425
gene id: 1897729:BOX17_RS04425
uniprot id: A0A1J0VE09
names: Similarity
messages: Belongs to the TPP enzyme family.

1897729:BOX17 RS06800
gene id: 1897729:BOX17_RS06800
uniprot id: A0A1J0VF72
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1897729:BOX17 RS14940
gene id: 1897729:BOX17_RS14940
uniprot id: A0A1J0VJB4
names: Similarity
messages: Belongs to the mannose-6-phosphate isomerase type 2 family.

1897729:BOX17 RS08770
gene id: 1897729:BOX17_RS08770
uniprot id: A0A1J0VG75
names: Function
names: Similarity
messages: Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control.
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

1897729:BOX17 RS01885
gene id: 1897729:BOX17_RS01885
uniprot id: A0A1J0VCP9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1897729:BOX17 RS05210
gene id: 1897729:BOX17_RS05210
uniprot id: A0A1J0VKA4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Membrane

1897729:BOX17 RS15365
gene id: 1897729:BOX17_RS15365
uniprot id: A0A1J0VJI3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase H family.
messages: Binds 1 Mg(2+) ion per subunit. May bind a second metal ion at a regulatory site, or after substrate binding.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Monomer.

1897729:BOX17 RS11495
gene id: 1897729:BOX17_RS11495
uniprot id: A0A1J0VHK2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COQ7 family.
messages: Binds 2 iron ions per subunit.
messages: Catalyzes the hydroxylation of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol during ubiquinone biosynthesis.
messages: Cell membrane

1897729:BOX17 RS02295
gene id: 1897729:BOX17_RS02295
uniprot id: A0A1J0VCX8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aldehyde dehydrogenase family.
messages: Binds 2 potassium ions per subunit.
messages: Dimer of dimers.
messages: Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the irreversible oxidation of betaine aldehyde to the corresponding acid.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1897729:BOX17 RS12960
gene id: 1897729:BOX17_RS12960
uniprot id: A0A1J0VIA4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L/F-transferase family.
messages: Cytoplasm
messages: Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.

1897729:BOX17 RS11075
gene id: 1897729:BOX17_RS11075
uniprot id: A0A1J0VHD1
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

1897729:BOX17 RS07305
gene id: 1897729:BOX17_RS07305
uniprot id: A0A1J0VFE7
names: Caution
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NosZ family.
messages: Binds 2 calcium ions per subunit.
messages: Binds 6 Cu cations per subunit. Each subunit contains 2 copper centers; Cu(A) (binuclear) and Cu(Z) (tetranuclear). Cu(Z) is thought to be the site of nitrous oxide reduction.
messages: Homodimer.
messages: In the C-terminal section; belongs to the cytochrome c oxidase subunit 2 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nitrous-oxide reductase is part of a bacterial respiratory system which is activated under anaerobic conditions in the presence of nitrate or nitrous oxide.
messages: Periplasm
messages: Predicted to be exported by the Tat system. The position of the signal peptide cleavage has not been experimentally proven.

1897729:BOX17 RS01260
gene id: 1897729:BOX17_RS01260
uniprot id: A0A1J0VCE2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PNP synthase family.
messages: Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.
messages: Cytoplasm
messages: Homooctamer; tetramer of dimers.

1897729:BOX17 RS04890
gene id: 1897729:BOX17_RS04890
uniprot id: A0A1J0VE99
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1897729:BOX17 RS10405
gene id: 1897729:BOX17_RS10405
uniprot id: A0A1J0VGZ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmB/CycW/HelB family.
messages: Cell inner membrane
messages: Membrane
messages: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.

1897729:BOX17 RS09280
gene id: 1897729:BOX17_RS09280
uniprot id: A0A1J0VGF2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SNF2/RAD54 helicase family. RapA subfamily.
messages: Interacts with the RNAP. Has a higher affinity for the core RNAP than for the holoenzyme. Its ATPase activity is stimulated by binding to RNAP.
messages: Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair.

1897729:BOX17 RS05860
gene id: 1897729:BOX17_RS05860
uniprot id: A0A1J0VKE4
names: Similarity
messages: Belongs to the intradiol ring-cleavage dioxygenase family.

1897729:BOX17 RS02260
gene id: 1897729:BOX17_RS02260
uniprot id: A0A1J0VCX6
names: Similarity
messages: Belongs to the peptidase S41A family.

1897729:BOX17 RS13430
gene id: 1897729:BOX17_RS13430
uniprot id: A0A1J0VIJ2
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1897729:BOX17 RS12870
gene id: 1897729:BOX17_RS12870
uniprot id: A0A1J0VI89
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

1897729:BOX17 RS08020
gene id: 1897729:BOX17_RS08020
uniprot id: A0A1J0VFU1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

1897729:BOX17 RS07025
gene id: 1897729:BOX17_RS07025
uniprot id: A0A1J0VFA1
names: Subcellular Location Annotation
messages: Membrane

1897729:BOX17 RS13505
gene id: 1897729:BOX17_RS13505
uniprot id: A0A1J0VIJ3
names: Similarity
messages: Belongs to the UPF0260 family.

1897729:BOX17 RS07600
gene id: 1897729:BOX17_RS07600
uniprot id: A0A1J0VFL8
names: Function
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.
messages: In the C-terminal section; belongs to the aldehyde dehydrogenase family.
messages: In the N-terminal section; belongs to the proline dehydrogenase family.
messages: Oxidizes proline to glutamate for use as a carbon and nitrogen source.

1897729:BOX17 RS10050
gene id: 1897729:BOX17_RS10050
uniprot id: A0A1J0VKL4
names: Caution
names: Function
names: Similarity
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1897729:BOX17 RS10665
gene id: 1897729:BOX17_RS10665
uniprot id: A0A1J0VH49
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1897729:BOX17 RS00510
gene id: 1897729:BOX17_RS00510
uniprot id: A0A1J0VC30
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily.
messages: Catalyzes the oxidation of L-aspartate to iminoaspartate.
messages: Cytoplasm

1897729:BOX17 RS07740
gene id: 1897729:BOX17_RS07740
uniprot id: A0A1J0VKH9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CysZ family.
messages: Cell inner membrane
messages: High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway.

1897729:BOX17 RS10935
gene id: 1897729:BOX17_RS10935
uniprot id: A0A1J0VHA8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

1897729:BOX17 RS16155
gene id: 1897729:BOX17_RS16155
uniprot id: A0A1J0VJY5
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.

1897729:BOX17 RS08230
gene id: 1897729:BOX17_RS08230
uniprot id: A0A1J0VG09
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

1897729:BOX17 RS06765
gene id: 1897729:BOX17_RS06765
uniprot id: A0A1J0VF82
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1897729:BOX17 RS06190
gene id: 1897729:BOX17_RS06190
uniprot id: A0A1J0VEY9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TmcA family.
messages: Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: nucleolus

1897729:BOX17 RS04675
gene id: 1897729:BOX17_RS04675
uniprot id: A0A1J0VE57
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the AspA/AstE family. Succinylglutamate desuccinylase subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Transforms N(2)-succinylglutamate into succinate and glutamate.

1897729:BOX17 RS12725
gene id: 1897729:BOX17_RS12725
uniprot id: A0A1J0VI82
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

1897729:BOX17 RS08465
gene id: 1897729:BOX17_RS08465
uniprot id: A0A1J0VG00
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

1897729:BOX17 RS12020
gene id: 1897729:BOX17_RS12020
uniprot id: A0A1J0VHV0
names: Similarity
messages: Belongs to the pirin family.

1897729:BOX17 RS00520
gene id: 1897729:BOX17_RS00520
uniprot id: A0A1J0VC16
names: Similarity
messages: Belongs to the SdhE FAD assembly factor family.

1897729:BOX17 RS07085
gene id: 1897729:BOX17_RS07085
uniprot id: A0A1J0VFE5
names: Function
names: Similarity
messages: Belongs to the peptidase S51 family.
messages: Exopeptidase that catalyzes the hydrolytic cleavage of multi-L-arginyl-poly-L-aspartic acid (cyanophycin; a water-insoluble reserve polymer) into aspartate-arginine dipeptides.

1897729:BOX17 RS05455
gene id: 1897729:BOX17_RS05455
uniprot id: A0A1J0VEJ3
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

1897729:BOX17 RS01575
gene id: 1897729:BOX17_RS01575
uniprot id: A0A1J0VCK6
names: Similarity
messages: Belongs to the fabD family.

1897729:BOX17 RS14455
gene id: 1897729:BOX17_RS14455
uniprot id: A0A1J0VKQ8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UreF family.
messages: Cytoplasm
messages: Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
messages: UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

1897729:BOX17 RS03310
gene id: 1897729:BOX17_RS03310
uniprot id: A0A1J0VDH2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm

1897729:BOX17 RS09540
gene id: 1897729:BOX17_RS09540
uniprot id: A0A1J0VGL2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

1897729:BOX17 RS04835
gene id: 1897729:BOX17_RS04835
uniprot id: A0A1J0VE71
names: Similarity
messages: Belongs to the carbamate kinase family.

1897729:BOX17 RS14430
gene id: 1897729:BOX17_RS14430
uniprot id: A0A1J0VJ20
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UreD family.
messages: Cytoplasm
messages: Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
messages: UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

1897729:BOX17 RS06005
gene id: 1897729:BOX17_RS06005
uniprot id: A0A1J0VEX5
names: Similarity
messages: Belongs to the nitroreductase family. HadB/RutE subfamily.

1897729:BOX17 RS09835
gene id: 1897729:BOX17_RS09835
uniprot id: A0A1J0VGR9
names: Subcellular Location Annotation
messages: Membrane

1897729:BOX17 RS06910
gene id: 1897729:BOX17_RS06910
uniprot id: A0A1J0VF85
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Membrane

1897729:BOX17 RS07430
gene id: 1897729:BOX17_RS07430
uniprot id: A0A1J0VFL7
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.

1897729:BOX17 RS07130
gene id: 1897729:BOX17_RS07130
uniprot id: A0A1J0VKH2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

1897729:BOX17 RS10725
gene id: 1897729:BOX17_RS10725
uniprot id: A0A1J0VH53
names: Cofactor
messages: Binds 1 [2Fe-2S] cluster per subunit.

1897729:BOX17 RS12060
gene id: 1897729:BOX17_RS12060
uniprot id: A0A1J0VHW2
names: Similarity
messages: Belongs to the peptidase M20A family. ArgE subfamily.

1897729:BOX17 RS16050
gene id: 1897729:BOX17_RS16050
uniprot id: A0A1J0VJU5
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit B family.

1897729:BOX17 RS09905
gene id: 1897729:BOX17_RS09905
uniprot id: A0A1J0VGQ5
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.

1897729:BOX17 RS14600
gene id: 1897729:BOX17_RS14600
uniprot id: A0A1J0VJ40
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nlpA lipoprotein family.
messages: Membrane

1897729:BOX17 RS06150
gene id: 1897729:BOX17_RS06150
uniprot id: A0A1J0VEY1
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1897729:BOX17 RS02310
gene id: 1897729:BOX17_RS02310
uniprot id: A0A1J0VCY8
names: Subcellular Location Annotation
messages: Membrane

1897729:BOX17 RS16090
gene id: 1897729:BOX17_RS16090
uniprot id: A0A1J0VJW4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

1897729:BOX17 RS15385
gene id: 1897729:BOX17_RS15385
uniprot id: A0A1J0VJJ4
names: Similarity
messages: Belongs to the peptidase S49 family.

1897729:BOX17 RS07990
gene id: 1897729:BOX17_RS07990
uniprot id: A0A1J0VFT6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
messages: Binds 1 potassium ion per subunit.
messages: Cytoplasm
messages: Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1897729:BOX17 RS07715
gene id: 1897729:BOX17_RS07715
uniprot id: A0A1J0VFL9
names: Similarity
messages: Belongs to the FAD-dependent oxidoreductase family.

1897729:BOX17 RS12685
gene id: 1897729:BOX17_RS12685
uniprot id: A0A1J0VI74
names: Similarity
messages: Belongs to the citrate synthase family.

1897729:BOX17 RS08655
gene id: 1897729:BOX17_RS08655
uniprot id: A0A1J0VG38
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1897729:BOX17 RS09755
gene id: 1897729:BOX17_RS09755
uniprot id: A0A1J0VGR0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein uS19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein uS19.

1897729:BOX17 RS13045
gene id: 1897729:BOX17_RS13045
uniprot id: A0A1J0VIC4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily.
messages: Cytoplasm
messages: Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity.

1897729:BOX17 RS01585
gene id: 1897729:BOX17_RS01585
uniprot id: A0A1J0VCM4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

1897729:BOX17 RS01825
gene id: 1897729:BOX17_RS01825
uniprot id: A0A1J0VCQ9
names: Similarity
messages: Belongs to the GST superfamily. HSP26 family.

1897729:BOX17 RS08365
gene id: 1897729:BOX17_RS08365
uniprot id: A0A1J0VG33
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

1897729:BOX17 RS09365
gene id: 1897729:BOX17_RS09365
uniprot id: A0A1J0VGG6
names: Similarity
messages: Belongs to the RutC family.

1897729:BOX17 RS09795
gene id: 1897729:BOX17_RS09795
uniprot id: A0A1J0VGQ0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1897729:BOX17 RS08585
gene id: 1897729:BOX17_RS08585
uniprot id: A0A1J0VG43
names: Similarity
messages: Belongs to the UPF0125 (RnfH) family.

1897729:BOX17 RS10190
gene id: 1897729:BOX17_RS10190
uniprot id: A0A1J0VGX8
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2).

1897729:BOX17 RS07780
gene id: 1897729:BOX17_RS07780
uniprot id: A0A1J0VFQ1
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

1897729:BOX17 RS01495
gene id: 1897729:BOX17_RS01495
uniprot id: A0A1J0VCH4
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

1897729:BOX17 RS05335
gene id: 1897729:BOX17_RS05335
uniprot id: A0A1J0VEK8
names: Similarity
messages: Belongs to the Nudix hydrolase family.

1897729:BOX17 RS05285
gene id: 1897729:BOX17_RS05285
uniprot id: A0A1J0VEF7
names: Caution
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: May also have succinyldiaminopimelate aminotransferase activity, thus carrying out the corresponding step in lysine biosynthesis.

1897729:BOX17 RS03460
gene id: 1897729:BOX17_RS03460
uniprot id: A0A1J0VDH1
names: Function
names: Similarity
messages: Belongs to the LDH/MDH superfamily. MDH type 2 family.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.

1897729:BOX17 RS04985
gene id: 1897729:BOX17_RS04985
uniprot id: A0A1J0VEA6
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1897729:BOX17 RS04940
gene id: 1897729:BOX17_RS04940
uniprot id: A0A1J0VE96
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MGMT family.
messages: Cytoplasm
messages: Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
messages: This enzyme catalyzes only one turnover and therefore is not strictly catalytic. According to one definition, an enzyme is a biocatalyst that acts repeatedly and over many reaction cycles.

1897729:BOX17 RS14330
gene id: 1897729:BOX17_RS14330
uniprot id: A0A1J0VJ02
names: Similarity
messages: Belongs to the pterin-4-alpha-carbinolamine dehydratase family.

1897729:BOX17 RS00675
gene id: 1897729:BOX17_RS00675
uniprot id: A0A1J0VC66
names: Subcellular Location Annotation
messages: Membrane

1897729:BOX17 RS04250
gene id: 1897729:BOX17_RS04250
uniprot id: A0A1J0VKC4
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

1897729:BOX17 RS15180
gene id: 1897729:BOX17_RS15180
uniprot id: A0A1J0VJF5
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

1897729:BOX17 RS11255
gene id: 1897729:BOX17_RS11255
uniprot id: A0A1J0VHF9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CcoP / FixP family.
messages: Binds 2 heme C groups per subunit.
messages: C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex.
messages: Cell inner membrane
messages: Component of the cbb3-type cytochrome c oxidase.

1897729:BOX17 RS01595
gene id: 1897729:BOX17_RS01595
uniprot id: A0A1J0VCK5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YceF subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes 7-methyl-GTP (m(7)GTP). May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

1897729:BOX17 RS04810
gene id: 1897729:BOX17_RS04810
uniprot id: A0A1J0VE86
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase A chain family.
messages: Cell membrane
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

1897729:BOX17 RS16505
gene id: 1897729:BOX17_RS16505
uniprot id: A0A1J0VK40
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenine deaminase type 2 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism.

1897729:BOX17 RS06240
gene id: 1897729:BOX17_RS06240
uniprot id: A0A1J0VEX6
names: Function
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. SpeA subfamily.
messages: Catalyzes the biosynthesis of agmatine from arginine.

1897729:BOX17 RS00740
gene id: 1897729:BOX17_RS00740
uniprot id: A0A1J0VC54
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1897729:BOX17 RS09125
gene id: 1897729:BOX17_RS09125
uniprot id: A0A1J0VGE8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

1897729:BOX17 RS07455
gene id: 1897729:BOX17_RS07455
uniprot id: A0A1J0VFI4
names: Subcellular Location Annotation
messages: Membrane

1897729:BOX17 RS14855
gene id: 1897729:BOX17_RS14855
uniprot id: A0A1J0VJ76
names: Similarity
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.

1897729:BOX17 RS03425
gene id: 1897729:BOX17_RS03425
uniprot id: A0A1J0VDI4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell membrane

1897729:BOX17 RS02370
gene id: 1897729:BOX17_RS02370
uniprot id: A0A1J0VCZ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1897729:BOX17 RS05850
gene id: 1897729:BOX17_RS05850
uniprot id: A0A1J0VET3
names: Similarity
messages: Belongs to the bacterial ring-hydroxylating dioxygenase beta subunit family.

1897729:BOX17 RS03370
gene id: 1897729:BOX17_RS03370
uniprot id: A0A1J0VDH3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methyltransferase superfamily. RsmC family.
messages: Cytoplasm
messages: Monomer.
messages: Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle.

1897729:BOX17 RS08335
gene id: 1897729:BOX17_RS08335
uniprot id: A0A1J0VFZ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0382 family.
messages: Membrane

1897729:BOX17 RS06250
gene id: 1897729:BOX17_RS06250
uniprot id: A0A1J0VEW8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PhyH family. EctD subfamily.
messages: Homodimer.
messages: Involved in the biosynthesis of 5-hydroxyectoine, called compatible solute, which helps organisms to survive extreme osmotic stress by acting as a highly soluble organic osmolyte. Catalyzes the 2-oxoglutarate-dependent selective hydroxylation of L-ectoine to yield (4S,5S)-5-hydroxyectoine.

1897729:BOX17 RS11625
gene id: 1897729:BOX17_RS11625
uniprot id: A0A1J0VKK6
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1897729:BOX17 RS00055
gene id: 1897729:BOX17_RS00055
uniprot id: A0A1J0VK45
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1897729:BOX17 RS07050
gene id: 1897729:BOX17_RS07050
uniprot id: A0A1J0VFA7
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1897729:BOX17 RS09535
gene id: 1897729:BOX17_RS09535
uniprot id: A0A1J0VGK9
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

1897729:BOX17 RS02945
gene id: 1897729:BOX17_RS02945
uniprot id: A0A1J0VK78
names: Subcellular Location Annotation
messages: Membrane

1897729:BOX17 RS02405
gene id: 1897729:BOX17_RS02405
uniprot id: A0A1J0VD00
names: Subcellular Location Annotation
messages: Membrane

1897729:BOX17 RS05960
gene id: 1897729:BOX17_RS05960
uniprot id: A0A1J0VES6
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1897729:BOX17 RS00985
gene id: 1897729:BOX17_RS00985
uniprot id: A0A1J0VC95
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1897729:BOX17 RS14230
gene id: 1897729:BOX17_RS14230
uniprot id: A0A1J0VIX3
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1897729:BOX17 RS12965
gene id: 1897729:BOX17_RS12965
uniprot id: A0A1J0VIC0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FtsK/SpoIIIE/SftA family.
messages: Membrane

1897729:BOX17 RS09450
gene id: 1897729:BOX17_RS09450
uniprot id: A0A1J0VGI4
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

1897729:BOX17 RS12535
gene id: 1897729:BOX17_RS12535
uniprot id: A0A1J0VI20
names: Similarity
messages: Belongs to the fructosamine kinase family.

1897729:BOX17 RS14445
gene id: 1897729:BOX17_RS14445
uniprot id: A0A1J0VJ03
names: Cofactor
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family.
messages: Binds 2 nickel ions per subunit.
messages: Carbamylation allows a single lysine to coordinate two nickel ions.
messages: Carboxylation allows a single lysine to coordinate two nickel ions.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

1897729:BOX17 RS08285
gene id: 1897729:BOX17_RS08285
uniprot id: A0A1J0VG10
names: Similarity
messages: Belongs to the ferredoxin--NADP reductase type 1 family.

1897729:BOX17 RS07170
gene id: 1897729:BOX17_RS07170
uniprot id: A0A1J0VFC5
names: Similarity
messages: Belongs to the radical SAM superfamily. Anaerobic sulfatase-maturating enzyme family.

1897729:BOX17 RS04395
gene id: 1897729:BOX17_RS04395
uniprot id: A0A1J0VDX4
names: Similarity
messages: Belongs to the bacterial solute-binding protein ModA family.

1897729:BOX17 RS09685
gene id: 1897729:BOX17_RS09685
uniprot id: A0A1J0VGP4
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1897729:BOX17 RS09695
gene id: 1897729:BOX17_RS09695
uniprot id: A0A1J0VGP6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MinC family.
messages: Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization.
messages: Interacts with MinD and FtsZ.

1897729:BOX17 RS08510
gene id: 1897729:BOX17_RS08510
uniprot id: A0A1J0VG06
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Involved in a late step of protoheme IX synthesis.
messages: Membrane

1897729:BOX17 RS08105
gene id: 1897729:BOX17_RS08105
uniprot id: A0A1J0VFV7
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

1897729:BOX17 RS01100
gene id: 1897729:BOX17_RS01100
uniprot id: A0A1J0VK58
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell inner membrane
messages: Membrane

1897729:BOX17 RS14150
gene id: 1897729:BOX17_RS14150
uniprot id: A0A1J0VIX2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: Membrane
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

1897729:BOX17 RS11580
gene id: 1897729:BOX17_RS11580
uniprot id: A0A1J0VHL8
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

1897729:BOX17 RS10300
gene id: 1897729:BOX17_RS10300
uniprot id: A0A1J0VH05
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Component of the RNA degradosome, which is a multiprotein complex involved in RNA processing and mRNA degradation.
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

1897729:BOX17 RS17230
gene id: 1897729:BOX17_RS17230
uniprot id: A0A1J0VGV0
names: Subcellular Location Annotation
messages: Cytoplasm

1897729:BOX17 RS14775
gene id: 1897729:BOX17_RS14775
uniprot id: A0A1J0VJ71
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S24 family.
messages: Homodimer.
messages: Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.

1897729:BOX17 RS01505
gene id: 1897729:BOX17_RS01505
uniprot id: A0A1J0VCM9
names: Similarity
messages: Belongs to the ETF beta-subunit/FixA family.

1897729:BOX17 RS03745
gene id: 1897729:BOX17_RS03745
uniprot id: A0A1J0VDN6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.

1897729:BOX17 RS14975
gene id: 1897729:BOX17_RS14975
uniprot id: A0A1J0VJ92
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

1897729:BOX17 RS05265
gene id: 1897729:BOX17_RS05265
uniprot id: A0A1J0VEG4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinylarginine dihydrolase family.
messages: Catalyzes the hydrolysis of N(2)-succinylarginine into N(2)-succinylornithine, ammonia and CO(2).
messages: Homodimer.

1897729:BOX17 RS15695
gene id: 1897729:BOX17_RS15695
uniprot id: A0A1J0VJP9
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

1897729:BOX17 RS07955
gene id: 1897729:BOX17_RS07955
uniprot id: A0A1J0VFT5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

1897729:BOX17 RS13935
gene id: 1897729:BOX17_RS13935
uniprot id: A0A1J0VIQ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. PrmA family.
messages: Cytoplasm
messages: Methylates ribosomal protein L11.

1897729:BOX17 RS09215
gene id: 1897729:BOX17_RS09215
uniprot id: A0A1J0VGG4
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

1897729:BOX17 RS00565
gene id: 1897729:BOX17_RS00565
uniprot id: A0A1J0VC63
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

1897729:BOX17 RS16310
gene id: 1897729:BOX17_RS16310
uniprot id: A0A1J0VJZ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1897729:BOX17 RS07560
gene id: 1897729:BOX17_RS07560
uniprot id: A0A1J0VFK6
names: Similarity
names: Subunit
messages: Belongs to the RNase H family.
messages: Monomer.

1897729:BOX17 RS07220
gene id: 1897729:BOX17_RS07220
uniprot id: A0A1J0VFD1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase U32 family. UbiU subfamily.
messages: Forms an heterodimer with UbiV.
messages: Required for O(2)-independent ubiquinone (coenzyme Q) biosynthesis. Together with UbiV, is essential for the C6-hydroxylation reaction in the oxygen-independent ubiquinone biosynthesis pathway.

1897729:BOX17 RS15900
gene id: 1897729:BOX17_RS15900
uniprot id: A0A1J0VJT7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phospholipase D family. Cardiolipin synthase subfamily. ClsA sub-subfamily.
messages: Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1897729:BOX17 RS07125
gene id: 1897729:BOX17_RS07125
uniprot id: A0A1J0VFB9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Membrane

1897729:BOX17 RS05640
gene id: 1897729:BOX17_RS05640
uniprot id: A0A1J0VEK6
names: Similarity
messages: Belongs to the glyoxalase I family.

1897729:BOX17 RS12520
gene id: 1897729:BOX17_RS12520
uniprot id: A0A1J0VI26
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1897729:BOX17 RS14110
gene id: 1897729:BOX17_RS14110
uniprot id: A0A1J0VIW7
names: Similarity
messages: Belongs to the YkuD family.

1897729:BOX17 RS06305
gene id: 1897729:BOX17_RS06305
uniprot id: A0A1J0VEX4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

1897729:BOX17 RS05135
gene id: 1897729:BOX17_RS05135
uniprot id: A0A1J0VKB7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LemA family.
messages: Membrane

1897729:BOX17 RS15370
gene id: 1897729:BOX17_RS15370
uniprot id: A0A1J0VJI0
names: Function
names: Subunit
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease.

1897729:BOX17 RS06625
gene id: 1897729:BOX17_RS06625
uniprot id: A0A1J0VF63
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

1897729:BOX17 RS05895
gene id: 1897729:BOX17_RS05895
uniprot id: A0A1J0VES0
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family.

1897729:BOX17 RS07995
gene id: 1897729:BOX17_RS07995
uniprot id: A0A1J0VFU3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Cell membrane
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

1897729:BOX17 RS01835
gene id: 1897729:BOX17_RS01835
uniprot id: A0A1J0VCQ4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome b family.
messages: Binds 2 heme groups non-covalently.
messages: Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.
messages: Membrane
messages: The main subunits of complex b-c1 are: cytochrome b, cytochrome c1 and the Rieske protein.

1897729:BOX17 RS00215
gene id: 1897729:BOX17_RS00215
uniprot id: A0A1J0VBY1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

1897729:BOX17 RS06175
gene id: 1897729:BOX17_RS06175
uniprot id: A0A1J0VF03
names: Function
names: Similarity
messages: Belongs to the RmuC family.
messages: Involved in DNA recombination.

1897729:BOX17 RS13005
gene id: 1897729:BOX17_RS13005
uniprot id: A0A1J0VIB1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
messages: Cell membrane
messages: Monomer.

1897729:BOX17 RS02975
gene id: 1897729:BOX17_RS02975
uniprot id: A0A1J0VDA0
names: Subcellular Location Annotation
messages: Cytoplasm

1897729:BOX17 RS06460
gene id: 1897729:BOX17_RS06460
uniprot id: A0A1J0VF14
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

1897729:BOX17 RS05270
gene id: 1897729:BOX17_RS05270
uniprot id: A0A1J0VEF5
names: Function
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family. AstD subfamily.
messages: Catalyzes the NAD-dependent reduction of succinylglutamate semialdehyde into succinylglutamate.

1897729:BOX17 RS12750
gene id: 1897729:BOX17_RS12750
uniprot id: A0A1J0VI65
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNR ribonuclease family. RNase II subfamily.
messages: Cytoplasm

1897729:BOX17 RS03315
gene id: 1897729:BOX17_RS03315
uniprot id: A0A1J0VDG6
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. Cx-SAM synthase family.
messages: Catalyzes the conversion of S-adenosyl-L-methionine (SAM) to carboxy-S-adenosyl-L-methionine (Cx-SAM).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1897729:BOX17 RS08450
gene id: 1897729:BOX17_RS08450
uniprot id: A0A1J0VG19
names: PTM
messages: Binds 2 heme c groups covalently per subunit.

1897729:BOX17 RS14520
gene id: 1897729:BOX17_RS14520
uniprot id: A0A1J0VJ41
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

1897729:BOX17 RS14580
gene id: 1897729:BOX17_RS14580
uniprot id: A0A1J0VJ49
names: Activity Regulation
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Inhibited by fructose 1,6-bisphosphate (FBP).
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.

1897729:BOX17 RS02240
gene id: 1897729:BOX17_RS02240
uniprot id: A0A1J0VD10
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

1897729:BOX17 RS09545
gene id: 1897729:BOX17_RS09545
uniprot id: A0A1J0VKK5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1897729:BOX17 RS04645
gene id: 1897729:BOX17_RS04645
uniprot id: A0A1J0VE53
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TVP38/TMEM64 family.
messages: Cell membrane
messages: Membrane

1897729:BOX17 RS07185
gene id: 1897729:BOX17_RS07185
uniprot id: A0A1J0VFD7
names: Similarity
names: Subunit
messages: Belongs to the Ahb/Nir family.
messages: Probably forms a complex composed of NirD, NirL, NirG and NirH. All proteins are required for the total conversion of siroheme to didecarboxysiroheme.

1897729:BOX17 RS06650
gene id: 1897729:BOX17_RS06650
uniprot id: A0A1J0VF84
names: Similarity
messages: Belongs to the leucine-binding protein family.

1897729:BOX17 RS05540
gene id: 1897729:BOX17_RS05540
uniprot id: A0A1J0VEK5
names: PTM
messages: Binds 1 heme c group covalently per subunit.

1897729:BOX17 RS11080
gene id: 1897729:BOX17_RS11080
uniprot id: A0A1J0VHC8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

1897729:BOX17 RS15785
gene id: 1897729:BOX17_RS15785
uniprot id: A0A1J0VJR4
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily. UbiG/COQ3 family.
messages: O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway.

1897729:BOX17 RS09995
gene id: 1897729:BOX17_RS09995
uniprot id: A0A1J0VGS1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type 2 tetrahydrodipicolinate N-succinyltransferase family.
messages: Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2-amino-6-oxopimelate using succinyl-CoA.
messages: Cytoplasm
messages: Homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1897729:BOX17 RS09825
gene id: 1897729:BOX17_RS09825
uniprot id: A0A1J0VGR8
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

1897729:BOX17 RS15110
gene id: 1897729:BOX17_RS15110
uniprot id: A0A1J0VJB6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LuxS family.
messages: Binds 1 Fe cation per subunit.
messages: Homodimer.
messages: Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD).

1897729:BOX17 RS00605
gene id: 1897729:BOX17_RS00605
uniprot id: A0A1J0VC69
names: Similarity
messages: Belongs to the histone deacetylase family.

1897729:BOX17 RS01975
gene id: 1897729:BOX17_RS01975
uniprot id: A0A1J0VCW7
names: Similarity
messages: Belongs to the peptidase U62 family.

1897729:BOX17 RS16040
gene id: 1897729:BOX17_RS16040
uniprot id: A0A1J0VJW1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Mg(2+). Can also accept Mn(2+).

1897729:BOX17 RS08780
gene id: 1897729:BOX17_RS08780
uniprot id: A0A1J0VG58
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1897729:BOX17 RS02025
gene id: 1897729:BOX17_RS02025
uniprot id: A0A1J0VCU8
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

1897729:BOX17 RS02630
gene id: 1897729:BOX17_RS02630
uniprot id: A0A1J0VD81
names: Similarity
messages: Belongs to the peptidase M42 family.

1897729:BOX17 RS08750
gene id: 1897729:BOX17_RS08750
uniprot id: A0A1J0VG85
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanD family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
messages: Cytoplasm
messages: Heterooctamer of four alpha and four beta subunits.
messages: Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus.

1897729:BOX17 RS01830
gene id: 1897729:BOX17_RS01830
uniprot id: A0A1J0VCP7
names: Cofactor
messages: Binds 1 heme c group covalently per subunit.

1897729:BOX17 RS13960
gene id: 1897729:BOX17_RS13960
uniprot id: A0A1J0VIT4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PPase family.
messages: Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
messages: Cytoplasm
messages: Homohexamer.

1897729:BOX17 RS11980
gene id: 1897729:BOX17_RS11980
uniprot id: A0A1J0VHU2
names: Similarity
messages: Belongs to the PhoH family.

1897729:BOX17 RS13185
gene id: 1897729:BOX17_RS13185
uniprot id: A0A1J0VID8
names: Similarity
messages: Belongs to the intradiol ring-cleavage dioxygenase family.

1897729:BOX17 RS03920
gene id: 1897729:BOX17_RS03920
uniprot id: A0A1J0VDS4
names: Similarity
messages: Belongs to the glucose-6-phosphate 1-epimerase family.

1897729:BOX17 RS14620
gene id: 1897729:BOX17_RS14620
uniprot id: A0A1J0VJ60
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Cell membrane
messages: Membrane

1897729:BOX17 RS03980
gene id: 1897729:BOX17_RS03980
uniprot id: A0A1J0VDQ6
names: Similarity
messages: Belongs to the universal stress protein A family.

1897729:BOX17 RS05795
gene id: 1897729:BOX17_RS05795
uniprot id: A0A1J0VEN2
names: Similarity
messages: To bacterial alkanal monooxygenase alpha and beta chains.

1897729:BOX17 RS02815
gene id: 1897729:BOX17_RS02815
uniprot id: A0A1J0VD57
names: Function
names: Similarity
names: Subunit
messages: Belongs to the isocitrate lyase/PEP mutase superfamily. Methylisocitrate lyase family.
messages: Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate.
messages: Homotetramer; dimer of dimers.
messages: Involved in the catabolism of short chain fatty acids (SCFA) via the 2-methylcitrate cycle (propionate degradation route). Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate via an alpha-carboxy-carbanion intermediate.

1897729:BOX17 RS03235
gene id: 1897729:BOX17_RS03235
uniprot id: A0A1J0VDE7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Belongs to the NnrE/AIBP family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1897729:BOX17 RS08600
gene id: 1897729:BOX17_RS08600
uniprot id: A0A1J0VG23
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

1897729:BOX17 RS14875
gene id: 1897729:BOX17_RS14875
uniprot id: A0A1J0VJ77
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

1897729:BOX17 RS09070
gene id: 1897729:BOX17_RS09070
uniprot id: A0A1J0VGB0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

1897729:BOX17 RS15740
gene id: 1897729:BOX17_RS15740
uniprot id: A0A1J0VJQ7
names: Similarity
messages: Belongs to the AB hydrolase superfamily. AB hydrolase 4 family.

1897729:BOX17 RS09150
gene id: 1897729:BOX17_RS09150
uniprot id: A0A1J0VGF9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

1897729:BOX17 RS12270
gene id: 1897729:BOX17_RS12270
uniprot id: A0A1J0VI07
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.

1897729:BOX17 RS09160
gene id: 1897729:BOX17_RS09160
uniprot id: A0A1J0VGC9
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

1897729:BOX17 RS12635
gene id: 1897729:BOX17_RS12635
uniprot id: A0A1J0VI66
names: Similarity
messages: Belongs to the SOS response-associated peptidase family.

1897729:BOX17 RS10990
gene id: 1897729:BOX17_RS10990
uniprot id: A0A1J0VHA7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2).
messages: Homodimer.

1897729:BOX17 RS08150
gene id: 1897729:BOX17_RS08150
uniprot id: A0A1J0VKI8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the BPG-independent phosphoglycerate mutase family.
messages: Binds 2 manganese ions per subunit.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: Monomer.

1897729:BOX17 RS11155
gene id: 1897729:BOX17_RS11155
uniprot id: A0A1J0VHF1
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPAT/DAPAT family.
messages: Cell membrane
messages: The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate.

1897729:BOX17 RS03070
gene id: 1897729:BOX17_RS03070
uniprot id: A0A1J0VDB6
names: Similarity
messages: Belongs to the transglycosylase Slt family.

1897729:BOX17 RS00085
gene id: 1897729:BOX17_RS00085
uniprot id: A0A1J0VBR9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.
messages: Binds 1 S-adenosyl-L-methionine per subunit.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1897729:BOX17 RS16025
gene id: 1897729:BOX17_RS16025
uniprot id: A0A1J0VJW0
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

1897729:BOX17 RS11630
gene id: 1897729:BOX17_RS11630
uniprot id: A0A1J0VHM3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1897729:BOX17 RS08160
gene id: 1897729:BOX17_RS08160
uniprot id: A0A1J0VFW4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecB family.
messages: Cytoplasm
messages: Homotetramer, a dimer of dimers. One homotetramer interacts with 1 SecA dimer.
messages: One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA.

1897729:BOX17 RS03125
gene id: 1897729:BOX17_RS03125
uniprot id: A0A1J0VDC1
names: Similarity
messages: Belongs to the peptidase M1 family.

1897729:BOX17 RS03510
gene id: 1897729:BOX17_RS03510
uniprot id: A0A1J0VDJ7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DsbB family.
messages: Cell inner membrane
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein.

1897729:BOX17 RS06060
gene id: 1897729:BOX17_RS06060
uniprot id: A0A1J0VEU1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

1897729:BOX17 RS16020
gene id: 1897729:BOX17_RS16020
uniprot id: A0A1J0VJV8
names: Similarity
messages: Belongs to the HupJ family.

1897729:BOX17 RS03940
gene id: 1897729:BOX17_RS03940
uniprot id: A0A1J0VDR1
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1897729:BOX17 RS12780
gene id: 1897729:BOX17_RS12780
uniprot id: A0A1J0VI76
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1897729:BOX17 RS10795
gene id: 1897729:BOX17_RS10795
uniprot id: A0A1J0VH88
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

1897729:BOX17 RS05305
gene id: 1897729:BOX17_RS05305
uniprot id: A0A1J0VEG0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TER reductase family.
messages: Involved in the final reduction of the elongation cycle of fatty acid synthesis (FAS II). Catalyzes the reduction of a carbon-carbon double bond in an enoyl moiety that is covalently linked to an acyl carrier protein (ACP).
messages: Monomer.