189425:PGRAT RS12895
gene id: 189425:PGRAT_RS12895
uniprot id: A0A089NHI5
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

189425:PGRAT RS20910
gene id: 189425:PGRAT_RS20910
uniprot id: A0A089MCB3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

189425:PGRAT RS31045
gene id: 189425:PGRAT_RS31045
uniprot id: A0A089MD79
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RnpA family.
messages: Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.
messages: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.

189425:PGRAT RS19570
gene id: 189425:PGRAT_RS19570
uniprot id: A0A089ME42
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Homodimer.
messages: Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate.

189425:PGRAT RS29295
gene id: 189425:PGRAT_RS29295
uniprot id: A0A089MCC6
names: PTM
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Hydantoinase/dihydropyrimidinase family.
messages: Carbamylation allows a single lysine to coordinate two divalent metal cations.

189425:PGRAT RS11585
gene id: 189425:PGRAT_RS11585
uniprot id: A0A089NGZ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

189425:PGRAT RS02295
gene id: 189425:PGRAT_RS02295
uniprot id: A0A089M2J7
names: Subcellular Location Annotation
messages: Membrane

189425:PGRAT RS14080
gene id: 189425:PGRAT_RS14080
uniprot id: A0A089M677
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

189425:PGRAT RS06340
gene id: 189425:PGRAT_RS06340
uniprot id: A0A089M0S3
names: Function
messages: Abolishes the inhibitory effect of tetracyclin on protein synthesis by a non-covalent modification of the ribosomes.

189425:PGRAT RS23285
gene id: 189425:PGRAT_RS23285
uniprot id: A0A089MDK0
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

189425:PGRAT RS06810
gene id: 189425:PGRAT_RS06810
uniprot id: A0A089M7J3
names: Function
messages: Decarboxylates L-threonine-O-3-phosphate to yield (R)-1-amino-2-propanol O-2-phosphate, the precursor for the linkage between the nucleotide loop and the corrin ring in cobalamin.

189425:PGRAT RS08665
gene id: 189425:PGRAT_RS08665
uniprot id: A0A089M8C4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An FAD-requiring monooxygenase active on some tetracycline antibiotic derivatives, which leads to their inactivation. Hydroxylates carbon 11a of tetracycline and some analogs.
messages: Belongs to the aromatic-ring hydroxylase family. TetX subfamily.
messages: Consists of an N-terminal FAD-binding domain with a Rossman fold and a C-terminal substrate-binding domain.
messages: Cytoplasm
messages: Monomer.

189425:PGRAT RS11010
gene id: 189425:PGRAT_RS11010
uniprot id: A0A089M9I0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DEAD box helicase family. DbpA subfamily.
messages: Contains an N-terminal domain that binds non-specifically to RNA and a C-terminal domain that binds specifically and tightly to hairpin 92 of 23S rRNA.
messages: Cytoplasm
messages: DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes.

189425:PGRAT RS12905
gene id: 189425:PGRAT_RS12905
uniprot id: A0A089M414
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.

189425:PGRAT RS14705
gene id: 189425:PGRAT_RS14705
uniprot id: A0A089NIJ0
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

189425:PGRAT RS18710
gene id: 189425:PGRAT_RS18710
uniprot id: A0A089M8L8
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

189425:PGRAT RS03465
gene id: 189425:PGRAT_RS03465
uniprot id: A0A089LZ81
names: Subcellular Location Annotation
messages: Membrane

189425:PGRAT RS28335
gene id: 189425:PGRAT_RS28335
uniprot id: A0A089NQE8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

189425:PGRAT RS23430
gene id: 189425:PGRAT_RS23430
uniprot id: A0A089NN11
names: Similarity
messages: Belongs to the transpeptidase family.

189425:PGRAT RS16350
gene id: 189425:PGRAT_RS16350
uniprot id: A0A089M9X2
names: Function
names: PTM
names: Similarity
messages: An intermediate of this reaction is the autophosphorylated ppk in which a phosphate is covalently linked to a histidine residue through a N-P bond.
messages: Belongs to the polyphosphate kinase 1 (PPK1) family.
messages: Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP).

189425:PGRAT RS30980
gene id: 189425:PGRAT_RS30980
uniprot id: A0A089MJT5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

189425:PGRAT RS11865
gene id: 189425:PGRAT_RS11865
uniprot id: A0A089M528
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L-fucose isomerase family.
messages: Converts the aldose L-fucose into the corresponding ketose L-fuculose.
messages: Cytoplasm

189425:PGRAT RS30200
gene id: 189425:PGRAT_RS30200
uniprot id: A0A089NRA5
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

189425:PGRAT RS02105
gene id: 189425:PGRAT_RS02105
uniprot id: A0A089M509
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit B family.

189425:PGRAT RS23460
gene id: 189425:PGRAT_RS23460
uniprot id: A0A089MDM5
names: Function
names: Similarity
messages: Belongs to the BshC family.
messages: Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH.

189425:PGRAT RS24910
gene id: 189425:PGRAT_RS24910
uniprot id: A0A089MBP5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

189425:PGRAT RS25325
gene id: 189425:PGRAT_RS25325
uniprot id: A0A089MH18
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the DyP-type peroxidase family.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group non-covalently per subunit.
messages: Involved in the recovery of exogenous heme iron. Extracts iron from heme while preserving the protoporphyrin ring intact.

189425:PGRAT RS26065
gene id: 189425:PGRAT_RS26065
uniprot id: A0A089MCD5
names: Function
names: Subunit
messages: Counteracts the endogenous Pycsar antiviral defense system. Phosphodiesterase that enables metal-dependent hydrolysis of host cyclic nucleotide Pycsar defense signals such as cCMP and cUMP.
messages: Homodimer.

189425:PGRAT RS24860
gene id: 189425:PGRAT_RS24860
uniprot id: A0A089NNQ2
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

189425:PGRAT RS28585
gene id: 189425:PGRAT_RS28585
uniprot id: A0A089MBZ3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Usually binds in the 5'-UTR at or near the Shine-Dalgarno sequence preventing ribosome-binding, thus repressing translation. Its main target seems to be the major flagellin gene, while its function is anatagonized by FliW.
messages: Belongs to the CsrA/RsmA family.
messages: Cytoplasm
messages: Homodimer; the beta-strands of each monomer intercalate to form a hydrophobic core, while the alpha-helices form wings that extend away from the core.

189425:PGRAT RS27130
gene id: 189425:PGRAT_RS27130
uniprot id: A0A089MB83
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

189425:PGRAT RS19980
gene id: 189425:PGRAT_RS19980
uniprot id: A0A089M991
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

189425:PGRAT RS11675
gene id: 189425:PGRAT_RS11675
uniprot id: A0A089NH04
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

189425:PGRAT RS11120
gene id: 189425:PGRAT_RS11120
uniprot id: A0A089M9J9
names: Similarity
messages: Belongs to the bacterial solute-binding protein 9 family.

189425:PGRAT RS28100
gene id: 189425:PGRAT_RS28100
uniprot id: A0A089MD75
names: Function
names: Similarity
messages: Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).

189425:PGRAT RS27995
gene id: 189425:PGRAT_RS27995
uniprot id: A0A089MBM8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

189425:PGRAT RS10410
gene id: 189425:PGRAT_RS10410
uniprot id: A0A089M993
names: Similarity
messages: Belongs to the alpha/beta-type SASP family.

189425:PGRAT RS19080
gene id: 189425:PGRAT_RS19080
uniprot id: A0A089MBC0
names: Subcellular Location Annotation
messages: Membrane

189425:PGRAT RS07695
gene id: 189425:PGRAT_RS07695
uniprot id: A0A089M5E7
names: Similarity
messages: Belongs to the 3-hydroxyacyl-CoA dehydrogenase family.

189425:PGRAT RS11525
gene id: 189425:PGRAT_RS11525
uniprot id: A0A089NGY2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. Xpt subfamily.
messages: Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis.
messages: Cytoplasm
messages: Homodimer.

189425:PGRAT RS24385
gene id: 189425:PGRAT_RS24385
uniprot id: A0A089M9Z7
names: Subcellular Location Annotation
messages: Membrane

189425:PGRAT RS15085
gene id: 189425:PGRAT_RS15085
uniprot id: A0A089MBV6
names: Similarity
messages: Belongs to the GerABKC lipoprotein family.

189425:PGRAT RS20740
gene id: 189425:PGRAT_RS20740
uniprot id: A0A089M9Q0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

189425:PGRAT RS21095
gene id: 189425:PGRAT_RS21095
uniprot id: A0A089NLV6
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane
messages: Membrane

189425:PGRAT RS08635
gene id: 189425:PGRAT_RS08635
uniprot id: A0A089M3H4
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

189425:PGRAT RS23675
gene id: 189425:PGRAT_RS23675
uniprot id: A0A089MG85
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial diacylglycerol kinase family.
messages: Membrane
messages: Mn(2+), Zn(2+), Cd(2+) and Co(2+) support activity to lesser extents.

189425:PGRAT RS25635
gene id: 189425:PGRAT_RS25635
uniprot id: A0A089MC26
names: Similarity
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.

189425:PGRAT RS11810
gene id: 189425:PGRAT_RS11810
uniprot id: A0A089M516
names: Similarity
messages: In the N-terminal section; belongs to the NADH:flavin oxidoreductase/NADH oxidase family.

189425:PGRAT RS25870
gene id: 189425:PGRAT_RS25870
uniprot id: A0A089NPB8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm
messages: Homodimer.

189425:PGRAT RS04320
gene id: 189425:PGRAT_RS04320
uniprot id: A0A089M3P2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 3B subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

189425:PGRAT RS19360
gene id: 189425:PGRAT_RS19360
uniprot id: A0A089MDZ8
names: Similarity
messages: Belongs to the ABC transporter superfamily.

189425:PGRAT RS10380
gene id: 189425:PGRAT_RS10380
uniprot id: A0A089M4F0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

189425:PGRAT RS09230
gene id: 189425:PGRAT_RS09230
uniprot id: A0A089M685
names: Subcellular Location Annotation
messages: Cell membrane

189425:PGRAT RS06220
gene id: 189425:PGRAT_RS06220
uniprot id: A0A089M299
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

189425:PGRAT RS13545
gene id: 189425:PGRAT_RS13545
uniprot id: A0A089M5Y5
names: Subcellular Location Annotation
messages: Membrane

189425:PGRAT RS27965
gene id: 189425:PGRAT_RS27965
uniprot id: A0A089MBM3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

189425:PGRAT RS30310
gene id: 189425:PGRAT_RS30310
uniprot id: A0A089MJD9
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

189425:PGRAT RS12670
gene id: 189425:PGRAT_RS12670
uniprot id: A0A089M3X5
names: Similarity
messages: Belongs to the peptidase C56 family.

189425:PGRAT RS28655
gene id: 189425:PGRAT_RS28655
uniprot id: A0A089MG61
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

189425:PGRAT RS07440
gene id: 189425:PGRAT_RS07440
uniprot id: A0A089M7S2
names: Subcellular Location Annotation
messages: Cell membrane

189425:PGRAT RS05460
gene id: 189425:PGRAT_RS05460
uniprot id: A0A089M6N9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane.

189425:PGRAT RS26820
gene id: 189425:PGRAT_RS26820
uniprot id: A0A089MB36
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

189425:PGRAT RS16215
gene id: 189425:PGRAT_RS16215
uniprot id: A0A089M7D3
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

189425:PGRAT RS30900
gene id: 189425:PGRAT_RS30900
uniprot id: A0A089MJR7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

189425:PGRAT RS04160
gene id: 189425:PGRAT_RS04160
uniprot id: A0A089M3M1
names: Function
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.
messages: Transcriptional repressor of xylose-utilizing enzymes.

189425:PGRAT RS09740
gene id: 189425:PGRAT_RS09740
uniprot id: A0A089M2J1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

189425:PGRAT RS29525
gene id: 189425:PGRAT_RS29525
uniprot id: A0A089ME00
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

189425:PGRAT RS23780
gene id: 189425:PGRAT_RS23780
uniprot id: A0A089NN66
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

189425:PGRAT RS08515
gene id: 189425:PGRAT_RS08515
uniprot id: A0A089M884
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

189425:PGRAT RS06950
gene id: 189425:PGRAT_RS06950
uniprot id: A0A089M2R0
names: Subcellular Location Annotation
messages: Membrane

189425:PGRAT RS00575
gene id: 189425:PGRAT_RS00575
uniprot id: A0A089NBP1
names: Similarity
messages: Belongs to the peptidase S8 family.

189425:PGRAT RS14075
gene id: 189425:PGRAT_RS14075
uniprot id: A0A089M4M5
names: Subcellular Location Annotation
messages: Membrane

189425:PGRAT RS17240
gene id: 189425:PGRAT_RS17240
uniprot id: A0A089NJV2
names: Similarity
messages: Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily.

189425:PGRAT RS10930
gene id: 189425:PGRAT_RS10930
uniprot id: A0A089NGM4
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

189425:PGRAT RS01135
gene id: 189425:PGRAT_RS01135
uniprot id: A0A089LZV7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

189425:PGRAT RS29180
gene id: 189425:PGRAT_RS29180
uniprot id: A0A089MDU9
names: Subcellular Location Annotation
messages: Membrane

189425:PGRAT RS25345
gene id: 189425:PGRAT_RS25345
uniprot id: A0A089MAF0
names: Cofactor
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. NagA family.
messages: Binds 1 divalent metal cation per subunit.

189425:PGRAT RS30825
gene id: 189425:PGRAT_RS30825
uniprot id: A0A089MJQ1
names: Subcellular Location Annotation
messages: Membrane

189425:PGRAT RS05160
gene id: 189425:PGRAT_RS05160
uniprot id: A0A089M032
names: Function
names: Similarity
messages: Belongs to the KptA/TPT1 family.
messages: Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP-ribose 1''-2''-cyclic phosphate (APPR>P). May function as an ADP-ribosylase.

189425:PGRAT RS02390
gene id: 189425:PGRAT_RS02390
uniprot id: A0A089M554
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

189425:PGRAT RS30135
gene id: 189425:PGRAT_RS30135
uniprot id: A0A089MCR1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Nitrate/nitrite porter (TC 2.A.1.8) family.
messages: Cell membrane
messages: Membrane

189425:PGRAT RS19355
gene id: 189425:PGRAT_RS19355
uniprot id: A0A089M8W7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

189425:PGRAT RS24550
gene id: 189425:PGRAT_RS24550
uniprot id: A0A089MGL8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MreD family.
messages: Membrane

189425:PGRAT RS11235
gene id: 189425:PGRAT_RS11235
uniprot id: A0A089M774
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

189425:PGRAT RS19350
gene id: 189425:PGRAT_RS19350
uniprot id: A0A089M7C8
names: Similarity
messages: Belongs to the CAPAB/TerDEXZ family.

189425:PGRAT RS28505
gene id: 189425:PGRAT_RS28505
uniprot id: A0A089MDF4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HPF/YfiA ribosome-associated protein family. Long HPF subfamily.
messages: Cytoplasm
messages: Interacts with 100S ribosomes.
messages: Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth.

189425:PGRAT RS26425
gene id: 189425:PGRAT_RS26425
uniprot id: A0A089MCH9
names: Similarity
messages: Belongs to the GbsR family.

189425:PGRAT RS17405
gene id: 189425:PGRAT_RS17405
uniprot id: A0A089M7Z3
names: Similarity
messages: Belongs to the UPF0234 family.

189425:PGRAT RS00855
gene id: 189425:PGRAT_RS00855
uniprot id: A0A089LXW7
names: Function
names: Similarity
messages: Belongs to the WhiA family.
messages: Involved in cell division and chromosome segregation.

189425:PGRAT RS20935
gene id: 189425:PGRAT_RS20935
uniprot id: A0A089MCB7
names: Subcellular Location Annotation
messages: Membrane

189425:PGRAT RS17335
gene id: 189425:PGRAT_RS17335
uniprot id: A0A089MCZ5
names: Function
names: Subunit
messages: Counteracts the endogenous Pycsar antiviral defense system. Phosphodiesterase that enables metal-dependent hydrolysis of host cyclic nucleotide Pycsar defense signals such as cCMP and cUMP.
messages: Homodimer.

189425:PGRAT RS06745
gene id: 189425:PGRAT_RS06745
uniprot id: A0A089M2M7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

189425:PGRAT RS19180
gene id: 189425:PGRAT_RS19180
uniprot id: A0A089NKU7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

189425:PGRAT RS08440
gene id: 189425:PGRAT_RS08440
uniprot id: A0A089NFE8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

189425:PGRAT RS16955
gene id: 189425:PGRAT_RS16955
uniprot id: A0A089M641
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily.

189425:PGRAT RS02095
gene id: 189425:PGRAT_RS02095
uniprot id: A0A089LYH7
names: Similarity
messages: Belongs to the TelA family.

189425:PGRAT RS23635
gene id: 189425:PGRAT_RS23635
uniprot id: A0A089MDQ5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoD/SigA subfamily.
messages: Cytoplasm
messages: Interacts transiently with the RNA polymerase catalytic core.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.

189425:PGRAT RS17770
gene id: 189425:PGRAT_RS17770
uniprot id: A0A089NK75
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliF family.
messages: Membrane
messages: The M ring may be actively involved in energy transduction.

189425:PGRAT RS29795
gene id: 189425:PGRAT_RS29795
uniprot id: A0A089ME35
names: Similarity
messages: Belongs to the AfsR/DnrI/RedD regulatory family.

189425:PGRAT RS02015
gene id: 189425:PGRAT_RS02015
uniprot id: A0A089M2E0
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily.

189425:PGRAT RS28525
gene id: 189425:PGRAT_RS28525
uniprot id: A0A089MG28
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

189425:PGRAT RS21600
gene id: 189425:PGRAT_RS21600
uniprot id: A0A089NM46
names: Function
names: Similarity
messages: Belongs to the mannonate dehydratase family.
messages: Catalyzes the dehydration of D-mannonate.

189425:PGRAT RS09435
gene id: 189425:PGRAT_RS09435
uniprot id: A0A089NFY6
names: Domain
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the CobB/CbiA family.
messages: Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source.
messages: Comprises of two domains. The C-terminal domain contains the binding site for glutamine and catalyzes the hydrolysis of this substrate to glutamate and ammonia. The N-terminal domain is anticipated to bind ATP and cobyrinate and catalyzes the ultimate synthesis of the diamide product. The ammonia produced via the glutaminase domain is probably translocated to the adjacent domain via a molecular tunnel, where it reacts with an activated intermediate.
messages: The a and c carboxylates of cobyrinate are activated for nucleophilic attack via formation of a phosphorylated intermediate by ATP. CbiA catalyzes first the amidation of the c-carboxylate, and then that of the a-carboxylate.

189425:PGRAT RS20205
gene id: 189425:PGRAT_RS20205
uniprot id: A0A089M7U5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscL family.
messages: Cell membrane
messages: Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
messages: Homopentamer.
messages: Membrane

189425:PGRAT RS30600
gene id: 189425:PGRAT_RS30600
uniprot id: A0A089NRI9
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

189425:PGRAT RS03000
gene id: 189425:PGRAT_RS03000
uniprot id: A0A089M0N7
names: Similarity
messages: Belongs to the thioredoxin family.

189425:PGRAT RS09835
gene id: 189425:PGRAT_RS09835
uniprot id: A0A089M918
names: Subcellular Location Annotation
messages: Membrane

189425:PGRAT RS24875
gene id: 189425:PGRAT_RS24875
uniprot id: A0A089MA77
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

189425:PGRAT RS13420
gene id: 189425:PGRAT_RS13420
uniprot id: A0A089M4B1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

189425:PGRAT RS13270
gene id: 189425:PGRAT_RS13270
uniprot id: A0A089M5U0
names: Subcellular Location Annotation
messages: Membrane

189425:PGRAT RS24305
gene id: 189425:PGRAT_RS24305
uniprot id: A0A089M9Y2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvC family.
messages: Binds 2 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer which binds Holliday junction (HJ) DNA. The HJ becomes 2-fold symmetrical on binding to RuvC with unstacked arms; it has a different conformation from HJ DNA in complex with RuvA. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair. Endonuclease that resolves HJ intermediates. Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction. The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'. Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange. HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

189425:PGRAT RS27845
gene id: 189425:PGRAT_RS27845
uniprot id: A0A089MD27
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

189425:PGRAT RS25340
gene id: 189425:PGRAT_RS25340
uniprot id: A0A089MJV9
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily.
messages: Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

189425:PGRAT RS07930
gene id: 189425:PGRAT_RS07930
uniprot id: A0A089M5J0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

189425:PGRAT RS25065
gene id: 189425:PGRAT_RS25065
uniprot id: A0A089MEE7
names: Function
names: Similarity
messages: Belongs to the NanE family.
messages: Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P).

189425:PGRAT RS17970
gene id: 189425:PGRAT_RS17970
uniprot id: A0A089M8A5
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.

189425:PGRAT RS15895
gene id: 189425:PGRAT_RS15895
uniprot id: A0A089MC56
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

189425:PGRAT RS30465
gene id: 189425:PGRAT_RS30465
uniprot id: A0A089MEF3
names: Similarity
messages: Belongs to the peptidase C40 family.

189425:PGRAT RS15695
gene id: 189425:PGRAT_RS15695
uniprot id: A0A089NJ07
names: Caution
names: Cofactor
names: Domain
names: Function
names: Similarity
messages: Belongs to the globin family. Two-domain flavohemoproteins subfamily.
messages: Binds 1 FAD per subunit.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.
messages: Consists of two distinct domains; an N-terminal heme-containing oxygen-binding domain and a C-terminal reductase domain with binding sites for FAD and NAD(P)H.
messages: In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
messages: Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

189425:PGRAT RS17710
gene id: 189425:PGRAT_RS17710
uniprot id: A0A089MD97
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliM family.
messages: Membrane

189425:PGRAT RS00325
gene id: 189425:PGRAT_RS00325
uniprot id: A0A089NBK0
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

189425:PGRAT RS28590
gene id: 189425:PGRAT_RS28590
uniprot id: A0A089MDG8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as an anti-CsrA protein, binds CsrA and prevents it from repressing translation of its target genes, one of which is flagellin. Binds to flagellin and participates in the assembly of the flagellum.
messages: Belongs to the FliW family.
messages: Cytoplasm
messages: Interacts with translational regulator CsrA and flagellin(s).

189425:PGRAT RS13755
gene id: 189425:PGRAT_RS13755
uniprot id: A0A089M4H2
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

189425:PGRAT RS16360
gene id: 189425:PGRAT_RS16360
uniprot id: A0A089M7F3
names: Subcellular Location Annotation
messages: Cell membrane

189425:PGRAT RS07740
gene id: 189425:PGRAT_RS07740
uniprot id: A0A089M338
names: Function
messages: Involved in some intermediate steps for the synthesis of the antibiotic polyketide bacillaene which is involved in secondary metabolism.

189425:PGRAT RS03735
gene id: 189425:PGRAT_RS03735
uniprot id: A0A089M603
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

189425:PGRAT RS28760
gene id: 189425:PGRAT_RS28760
uniprot id: A0A089MG86
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

189425:PGRAT RS13000
gene id: 189425:PGRAT_RS13000
uniprot id: A0A089MAP2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

189425:PGRAT RS11655
gene id: 189425:PGRAT_RS11655
uniprot id: A0A089M7F0
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase class-2 family.
messages: Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.

189425:PGRAT RS24625
gene id: 189425:PGRAT_RS24625
uniprot id: A0A089ME62
names: Subcellular Location Annotation
messages: Membrane

189425:PGRAT RS01750
gene id: 189425:PGRAT_RS01750
uniprot id: A0A089M049
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

189425:PGRAT RS16205
gene id: 189425:PGRAT_RS16205
uniprot id: A0A089M9U5
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

189425:PGRAT RS15080
gene id: 189425:PGRAT_RS15080
uniprot id: A0A089M6V7
names: Similarity
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Spore germination protein (SGP) (TC 2.A.3.9) family.

189425:PGRAT RS11310
gene id: 189425:PGRAT_RS11310
uniprot id: A0A089NGU6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M3B family.
messages: Binds 1 zinc ion.
messages: Has oligopeptidase activity and degrades a variety of small bioactive peptides.

189425:PGRAT RS00745
gene id: 189425:PGRAT_RS00745
uniprot id: A0A089NBR4
names: Similarity
messages: Belongs to the FGGY kinase family.

189425:PGRAT RS30770
gene id: 189425:PGRAT_RS30770
uniprot id: A0A089NRM4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

189425:PGRAT RS19915
gene id: 189425:PGRAT_RS19915
uniprot id: A0A089NL95
names: Caution
names: Function
names: Similarity
messages: Belongs to the UbiX/PAD1 family.
messages: Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

189425:PGRAT RS23940
gene id: 189425:PGRAT_RS23940
uniprot id: A0A089MB80
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

189425:PGRAT RS28460
gene id: 189425:PGRAT_RS28460
uniprot id: A0A089MII9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.

189425:PGRAT RS30935
gene id: 189425:PGRAT_RS30935
uniprot id: A0A089MHA0
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

189425:PGRAT RS07215
gene id: 189425:PGRAT_RS07215
uniprot id: A0A089M564
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.
messages: Cell membrane
messages: Membrane
messages: Probable transporter of a GTP-driven Fe(2+) uptake system.

189425:PGRAT RS13750
gene id: 189425:PGRAT_RS13750
uniprot id: A0A089M8I9
names: Similarity
messages: Belongs to the zinc-associated anti-sigma factor (ZAS) superfamily. Anti-sigma-W factor family.

189425:PGRAT RS05535
gene id: 189425:PGRAT_RS05535
uniprot id: A0A089M1X2
names: Similarity
messages: Belongs to the glutamate synthase family.

189425:PGRAT RS24450
gene id: 189425:PGRAT_RS24450
uniprot id: A0A089MGJ5
names: Function
names: Similarity
messages: Acts on leucine, isoleucine and valine.
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

189425:PGRAT RS21535
gene id: 189425:PGRAT_RS21535
uniprot id: A0A089M8J6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

189425:PGRAT RS12950
gene id: 189425:PGRAT_RS12950
uniprot id: A0A089NHJ4
names: Function
names: Similarity
messages: Belongs to the helicase family. RecG subfamily.
messages: Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA).

189425:PGRAT RS03635
gene id: 189425:PGRAT_RS03635
uniprot id: A0A089ND24
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

189425:PGRAT RS22450
gene id: 189425:PGRAT_RS22450
uniprot id: A0A089MAH6
names: Cofactor
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.

189425:PGRAT RS17545
gene id: 189425:PGRAT_RS17545
uniprot id: A0A089MAN3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

189425:PGRAT RS13815
gene id: 189425:PGRAT_RS13815
uniprot id: A0A089MB27
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

189425:PGRAT RS25390
gene id: 189425:PGRAT_RS25390
uniprot id: A0A089MEK6
names: Similarity
messages: Belongs to the polysaccharide synthase family.

189425:PGRAT RS28195
gene id: 189425:PGRAT_RS28195
uniprot id: A0A089MD93
names: Subcellular Location Annotation
messages: Membrane

189425:PGRAT RS26005
gene id: 189425:PGRAT_RS26005
uniprot id: A0A089NPD3
names: Similarity
messages: Belongs to the ABC transporter superfamily.

189425:PGRAT RS14320
gene id: 189425:PGRAT_RS14320
uniprot id: A0A089MBE3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferritin family. Prokaryotic subfamily.
messages: Cytoplasm
messages: Iron-storage protein.

189425:PGRAT RS22075
gene id: 189425:PGRAT_RS22075
uniprot id: A0A089MFG3
names: Subcellular Location Annotation
messages: Membrane

189425:PGRAT RS23540
gene id: 189425:PGRAT_RS23540
uniprot id: A0A089M9J7
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

189425:PGRAT RS17880
gene id: 189425:PGRAT_RS17880
uniprot id: A0A089MAS8
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

189425:PGRAT RS02100
gene id: 189425:PGRAT_RS02100
uniprot id: A0A089M093
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FNT transporter (TC 2.A.44) family.
messages: Membrane

189425:PGRAT RS05605
gene id: 189425:PGRAT_RS05605
uniprot id: A0A089M0B0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

189425:PGRAT RS17315
gene id: 189425:PGRAT_RS17315
uniprot id: A0A089NJW3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the fosfomycin resistance protein family. FosB subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor.

189425:PGRAT RS30560
gene id: 189425:PGRAT_RS30560
uniprot id: A0A089MCZ3
names: Subcellular Location Annotation
messages: Membrane

189425:PGRAT RS25100
gene id: 189425:PGRAT_RS25100
uniprot id: A0A089MAA5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

189425:PGRAT RS13505
gene id: 189425:PGRAT_RS13505
uniprot id: A0A089M4C8
names: Similarity
messages: Belongs to the citrate synthase family.

189425:PGRAT RS26605
gene id: 189425:PGRAT_RS26605
uniprot id: A0A089NPK4
names: Similarity
messages: Belongs to the tRNA methyltransferase O family.

189425:PGRAT RS28090
gene id: 189425:PGRAT_RS28090
uniprot id: A0A089MFU6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

189425:PGRAT RS05715
gene id: 189425:PGRAT_RS05715
uniprot id: A0A089M6U7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. EmrB family.
messages: Cell membrane
messages: Membrane

189425:PGRAT RS26355
gene id: 189425:PGRAT_RS26355
uniprot id: A0A089MAY0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

189425:PGRAT RS02985
gene id: 189425:PGRAT_RS02985
uniprot id: A0A089NCR7
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

189425:PGRAT RS19990
gene id: 189425:PGRAT_RS19990
uniprot id: A0A089NLB1
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

189425:PGRAT RS26400
gene id: 189425:PGRAT_RS26400
uniprot id: A0A089NPH8
names: Subcellular Location Annotation
messages: Membrane

189425:PGRAT RS20495
gene id: 189425:PGRAT_RS20495
uniprot id: A0A089NLM1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

189425:PGRAT RS20355
gene id: 189425:PGRAT_RS20355
uniprot id: A0A089MEP2
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

189425:PGRAT RS25210
gene id: 189425:PGRAT_RS25210
uniprot id: A0A089MAC3
names: Subcellular Location Annotation
messages: Cell membrane

189425:PGRAT RS16370
gene id: 189425:PGRAT_RS16370
uniprot id: A0A089NJB6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 3 family.
messages: Cell membrane
messages: Membrane

189425:PGRAT RS10285
gene id: 189425:PGRAT_RS10285
uniprot id: A0A089NGB3
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

189425:PGRAT RS22670
gene id: 189425:PGRAT_RS22670
uniprot id: A0A089NMP1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

189425:PGRAT RS19660
gene id: 189425:PGRAT_RS19660
uniprot id: A0A089MBN1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

189425:PGRAT RS03715
gene id: 189425:PGRAT_RS03715
uniprot id: A0A089ND52
names: Subcellular Location Annotation
messages: Membrane

189425:PGRAT RS27280
gene id: 189425:PGRAT_RS27280
uniprot id: A0A089NPT7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ArsB family.
messages: Belongs to the CitM (TC 2.A.11) transporter family.
messages: Cell membrane
messages: Membrane

189425:PGRAT RS14805
gene id: 189425:PGRAT_RS14805
uniprot id: A0A089MBP8
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

189425:PGRAT RS15665
gene id: 189425:PGRAT_RS15665
uniprot id: A0A089NJ01
names: Subcellular Location Annotation
messages: Membrane

189425:PGRAT RS23715
gene id: 189425:PGRAT_RS23715
uniprot id: A0A089M9M4
names: Subcellular Location Annotation
messages: Membrane

189425:PGRAT RS28855
gene id: 189425:PGRAT_RS28855
uniprot id: A0A089NQR3
names: Subcellular Location Annotation
messages: Membrane

189425:PGRAT RS23410
gene id: 189425:PGRAT_RS23410
uniprot id: A0A089MDL8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

189425:PGRAT RS30775
gene id: 189425:PGRAT_RS30775
uniprot id: A0A089MH65
names: Similarity
messages: Belongs to the IF-3 family.

189425:PGRAT RS05205
gene id: 189425:PGRAT_RS05205
uniprot id: A0A089NDS3
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PPase class C family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm

189425:PGRAT RS03985
gene id: 189425:PGRAT_RS03985
uniprot id: A0A089LZK5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HsdR family.
messages: Subunit R is required for both nuclease and ATPase activities, but not for modification.
messages: The type I restriction/modification system is composed of three polypeptides R, M and S.

189425:PGRAT RS20625
gene id: 189425:PGRAT_RS20625
uniprot id: A0A089MC74
names: Subcellular Location Annotation
messages: Membrane

189425:PGRAT RS23420
gene id: 189425:PGRAT_RS23420
uniprot id: A0A089MB02
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

189425:PGRAT RS29435
gene id: 189425:PGRAT_RS29435
uniprot id: A0A089MCE9
names: Function
names: Similarity
messages: Belongs to the MqnA/MqnD family. MqnD subfamily.
messages: Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2).

189425:PGRAT RS28425
gene id: 189425:PGRAT_RS28425
uniprot id: A0A089MBV8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Homodimer. Forms a membrane-associated complex with FtsX.
messages: Part of the ABC transporter FtsEX involved in cellular division.

189425:PGRAT RS15635
gene id: 189425:PGRAT_RS15635
uniprot id: A0A089MC21
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. MoaA family.
messages: Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.
messages: Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
messages: Monomer and homodimer.

189425:PGRAT RS04850
gene id: 189425:PGRAT_RS04850
uniprot id: A0A089LZX8
names: Similarity
messages: Belongs to the glycosyl hydrolase 42 family.

189425:PGRAT RS17320
gene id: 189425:PGRAT_RS17320
uniprot id: A0A089MAE7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the heat shock protein 90 family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Molecular chaperone. Has ATPase activity.

189425:PGRAT RS16630
gene id: 189425:PGRAT_RS16630
uniprot id: A0A089NJH4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S24 family.
messages: Homodimer.
messages: Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.

189425:PGRAT RS01755
gene id: 189425:PGRAT_RS01755
uniprot id: A0A089M4V6
names: Similarity
messages: Belongs to the ABC transporter superfamily.

189425:PGRAT RS17875
gene id: 189425:PGRAT_RS17875
uniprot id: A0A089NK92
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Cell membrane
messages: Membrane

189425:PGRAT RS19040
gene id: 189425:PGRAT_RS19040
uniprot id: A0A089MDT9
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

189425:PGRAT RS25175
gene id: 189425:PGRAT_RS25175
uniprot id: A0A089NNW2
names: Similarity
messages: Belongs to the NifX/NifY family.

189425:PGRAT RS16105
gene id: 189425:PGRAT_RS16105
uniprot id: A0A089NJ67
names: Subcellular Location Annotation
messages: Membrane

189425:PGRAT RS26250
gene id: 189425:PGRAT_RS26250
uniprot id: A0A089MCF5
names: Similarity
messages: Belongs to the acyltransferase 3 family.

189425:PGRAT RS00615
gene id: 189425:PGRAT_RS00615
uniprot id: A0A089LZI1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

189425:PGRAT RS15535
gene id: 189425:PGRAT_RS15535
uniprot id: A0A089M9H9
names: Subcellular Location Annotation
messages: Cell membrane

189425:PGRAT RS03850
gene id: 189425:PGRAT_RS03850
uniprot id: A0A089M628
names: Subcellular Location Annotation
messages: Membrane

189425:PGRAT RS19260
gene id: 189425:PGRAT_RS19260
uniprot id: A0A089M7B3
names: Subunit
messages: Interacts transiently with the RNA polymerase catalytic core formed by RpoA, RpoB, RpoC and RpoZ (2 alpha, 1 beta, 1 beta' and 1 omega subunit) to form the RNA polymerase holoenzyme that can initiate transcription.

189425:PGRAT RS19720
gene id: 189425:PGRAT_RS19720
uniprot id: A0A089M943
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

189425:PGRAT RS03340
gene id: 189425:PGRAT_RS03340
uniprot id: A0A089LZ59
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

189425:PGRAT RS03095
gene id: 189425:PGRAT_RS03095
uniprot id: A0A089M2Z8
names: Similarity
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Spore germination protein (SGP) (TC 2.A.3.9) family.

189425:PGRAT RS20640
gene id: 189425:PGRAT_RS20640
uniprot id: A0A089MET4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidine kinase family.
messages: Cytoplasm
messages: Homotetramer.

189425:PGRAT RS00905
gene id: 189425:PGRAT_RS00905
uniprot id: A0A089M1V1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

189425:PGRAT RS09940
gene id: 189425:PGRAT_RS09940
uniprot id: A0A089NG55
names: Similarity
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Spore germination protein (SGP) (TC 2.A.3.9) family.

189425:PGRAT RS00285
gene id: 189425:PGRAT_RS00285
uniprot id: A0A089LZB9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm

189425:PGRAT RS06990
gene id: 189425:PGRAT_RS06990
uniprot id: A0A089NEP6
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

189425:PGRAT RS14810
gene id: 189425:PGRAT_RS14810
uniprot id: A0A089NIK7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family. YeeN subfamily.
messages: Cytoplasm

189425:PGRAT RS24565
gene id: 189425:PGRAT_RS24565
uniprot id: A0A089MA23
names: Similarity
messages: Belongs to the UPF0758 family.

189425:PGRAT RS07765
gene id: 189425:PGRAT_RS07765
uniprot id: A0A089M1I6
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

189425:PGRAT RS05475
gene id: 189425:PGRAT_RS05475
uniprot id: A0A089M084
names: Subcellular Location Annotation
messages: Membrane

189425:PGRAT RS13965
gene id: 189425:PGRAT_RS13965
uniprot id: A0A089NI40
names: Similarity
messages: Belongs to the fabD family.

189425:PGRAT RS28015
gene id: 189425:PGRAT_RS28015
uniprot id: A0A089MFS8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

189425:PGRAT RS24730
gene id: 189425:PGRAT_RS24730
uniprot id: A0A089NNM1
names: Similarity
messages: Belongs to the acyltransferase 3 family.

189425:PGRAT RS27910
gene id: 189425:PGRAT_RS27910
uniprot id: A0A089MFQ8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

189425:PGRAT RS28075
gene id: 189425:PGRAT_RS28075
uniprot id: A0A089MD68
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MrnC RNase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc); Rnc processes 30S rRNA into smaller rRNA precursors.

189425:PGRAT RS06025
gene id: 189425:PGRAT_RS06025
uniprot id: A0A089M269
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

189425:PGRAT RS00780
gene id: 189425:PGRAT_RS00780
uniprot id: A0A089LXU8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

189425:PGRAT RS07475
gene id: 189425:PGRAT_RS07475
uniprot id: A0A089M5A5
names: Subcellular Location Annotation
messages: Membrane

189425:PGRAT RS03055
gene id: 189425:PGRAT_RS03055
uniprot id: A0A089M0P9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Membrane

189425:PGRAT RS23270
gene id: 189425:PGRAT_RS23270
uniprot id: A0A089MAX9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.

189425:PGRAT RS17595
gene id: 189425:PGRAT_RS17595
uniprot id: A0A089MAN9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

189425:PGRAT RS07320
gene id: 189425:PGRAT_RS07320
uniprot id: A0A089M580
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily.
messages: Catalyzes the hydrolysis of 5-hydroxyisourate (HIU) to 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU).
messages: Homotetramer.

189425:PGRAT RS12045
gene id: 189425:PGRAT_RS12045
uniprot id: A0A089M3M2
names: Function
names: Subunit
messages: Counteracts the endogenous Pycsar antiviral defense system. Phosphodiesterase that enables metal-dependent hydrolysis of host cyclic nucleotide Pycsar defense signals such as cCMP and cUMP.
messages: Homodimer.

189425:PGRAT RS00900
gene id: 189425:PGRAT_RS00900
uniprot id: A0A089NBU2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Monomer.

189425:PGRAT RS13930
gene id: 189425:PGRAT_RS13930
uniprot id: A0A089M644
names: Similarity
messages: Belongs to the peptidase S16 family.

189425:PGRAT RS05640
gene id: 189425:PGRAT_RS05640
uniprot id: A0A089M6S7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell membrane
messages: Forms a complex with TatA.
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.

189425:PGRAT RS17670
gene id: 189425:PGRAT_RS17670
uniprot id: A0A089MAQ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.
messages: Cell membrane
messages: Membrane
messages: Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

189425:PGRAT RS07870
gene id: 189425:PGRAT_RS07870
uniprot id: A0A089M354
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

189425:PGRAT RS14680
gene id: 189425:PGRAT_RS14680
uniprot id: A0A089NII4
names: Similarity
messages: Belongs to the glycosyl hydrolase 130 family.

189425:PGRAT RS24470
gene id: 189425:PGRAT_RS24470
uniprot id: A0A089MBG7
names: Similarity
messages: Belongs to the UPF0735 family.

189425:PGRAT RS09120
gene id: 189425:PGRAT_RS09120
uniprot id: A0A089M8M3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the galactose-1-phosphate uridylyltransferase type 2 family.
messages: Cytoplasm

189425:PGRAT RS23650
gene id: 189425:PGRAT_RS23650
uniprot id: A0A089MG82
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

189425:PGRAT RS05560
gene id: 189425:PGRAT_RS05560
uniprot id: A0A089M1X6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phospholipase D family. Cardiolipin synthase subfamily.
messages: Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

189425:PGRAT RS17500
gene id: 189425:PGRAT_RS17500
uniprot id: A0A089M6G0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

189425:PGRAT RS16590
gene id: 189425:PGRAT_RS16590
uniprot id: A0A089M5X8
names: Similarity
names: Subunit
messages: Belongs to the FPG family.
messages: Monomer.

189425:PGRAT RS00860
gene id: 189425:PGRAT_RS00860
uniprot id: A0A089LZN0
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The phosphoryl group from phosphoenolpyruvate (PEP) is transferred to the phosphoryl carrier protein HPr by enzyme I. Phospho-HPr then transfers it to the PTS EIIA domain.

189425:PGRAT RS23920
gene id: 189425:PGRAT_RS23920
uniprot id: A0A089MGB5
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

189425:PGRAT RS29810
gene id: 189425:PGRAT_RS29810
uniprot id: A0A089MGP6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. Xpt subfamily.
messages: Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis.
messages: Cytoplasm
messages: Homodimer.

189425:PGRAT RS24095
gene id: 189425:PGRAT_RS24095
uniprot id: A0A089M9U2
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

189425:PGRAT RS09910
gene id: 189425:PGRAT_RS09910
uniprot id: A0A089M929
names: Similarity
messages: Belongs to the manganese catalase family.

189425:PGRAT RS05090
gene id: 189425:PGRAT_RS05090
uniprot id: A0A089M1Q2
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

189425:PGRAT RS22420
gene id: 189425:PGRAT_RS22420
uniprot id: A0A089M8Z4
names: Similarity
messages: Belongs to the transposase 11 family.

189425:PGRAT RS17310
gene id: 189425:PGRAT_RS17310
uniprot id: A0A089MCY9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

189425:PGRAT RS04410
gene id: 189425:PGRAT_RS04410
uniprot id: A0A089M697
names: Subcellular Location Annotation
messages: Membrane

189425:PGRAT RS10340
gene id: 189425:PGRAT_RS10340
uniprot id: A0A089M6Q4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ThiG family.
messages: Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
messages: Cytoplasm
messages: Homotetramer. Forms heterodimers with either ThiH or ThiS.

189425:PGRAT RS19780
gene id: 189425:PGRAT_RS19780
uniprot id: A0A089M955
names: Subcellular Location Annotation
messages: Membrane

189425:PGRAT RS22725
gene id: 189425:PGRAT_RS22725
uniprot id: A0A089MFR1
names: Similarity
messages: Belongs to the FGGY kinase family.

189425:PGRAT RS12935
gene id: 189425:PGRAT_RS12935
uniprot id: A0A089M419
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

189425:PGRAT RS17955
gene id: 189425:PGRAT_RS17955
uniprot id: A0A089NKA7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0073 (Hly-III) family.
messages: Membrane

189425:PGRAT RS25320
gene id: 189425:PGRAT_RS25320
uniprot id: A0A089MBW6
names: Similarity
messages: Belongs to the EfeM/EfeO family.

189425:PGRAT RS19490
gene id: 189425:PGRAT_RS19490
uniprot id: A0A089M8Z6
names: Subcellular Location Annotation
messages: Membrane

189425:PGRAT RS11965
gene id: 189425:PGRAT_RS11965
uniprot id: A0A089M7L5
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 51 family.
messages: Homohexamer; trimer of dimers.

189425:PGRAT RS28145
gene id: 189425:PGRAT_RS28145
uniprot id: A0A089MBQ7
names: Similarity
messages: Belongs to the CtsR family.

189425:PGRAT RS28910
gene id: 189425:PGRAT_RS28910
uniprot id: A0A089NQS1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. MoaA family.
messages: Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.
messages: Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
messages: Monomer and homodimer.

189425:PGRAT RS24640
gene id: 189425:PGRAT_RS24640
uniprot id: A0A089MBJ5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

189425:PGRAT RS23390
gene id: 189425:PGRAT_RS23390
uniprot id: A0A089M9H4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FtsQ/DivIB family. DivIB subfamily.
messages: Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex.
messages: Cell membrane

189425:PGRAT RS01815
gene id: 189425:PGRAT_RS01815
uniprot id: A0A089NC86
names: Subcellular Location Annotation
messages: Membrane

189425:PGRAT RS12875
gene id: 189425:PGRAT_RS12875
uniprot id: A0A089M834
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

189425:PGRAT RS22295
gene id: 189425:PGRAT_RS22295
uniprot id: A0A089MAF1
names: Similarity
messages: Belongs to the peptidase A24 family.

189425:PGRAT RS08005
gene id: 189425:PGRAT_RS08005
uniprot id: A0A089NF72
names: Subcellular Location Annotation
messages: Cell membrane

189425:PGRAT RS00365
gene id: 189425:PGRAT_RS00365
uniprot id: A0A089LZD4
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

189425:PGRAT RS27105
gene id: 189425:PGRAT_RS27105
uniprot id: A0A089MCQ8
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the xylose isomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.

189425:PGRAT RS24555
gene id: 189425:PGRAT_RS24555
uniprot id: A0A089NNI6
names: Function
names: Similarity
messages: Belongs to the MreC family.
messages: Involved in formation and maintenance of cell shape.

189425:PGRAT RS08940
gene id: 189425:PGRAT_RS08940
uniprot id: A0A089NFN7
names: Similarity
messages: Belongs to the UPF0297 family.

189425:PGRAT RS03580
gene id: 189425:PGRAT_RS03580
uniprot id: A0A089M5V7
names: Similarity
messages: Belongs to the universal stress protein A family.

189425:PGRAT RS07915
gene id: 189425:PGRAT_RS07915
uniprot id: A0A089M358
names: Subcellular Location Annotation
messages: Membrane

189425:PGRAT RS11000
gene id: 189425:PGRAT_RS11000
uniprot id: A0A089M329
names: Similarity
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Homodimer.

189425:PGRAT RS03445
gene id: 189425:PGRAT_RS03445
uniprot id: A0A089NCZ3
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

189425:PGRAT RS26995
gene id: 189425:PGRAT_RS26995
uniprot id: A0A089MCP0
names: Subcellular Location Annotation
messages: Membrane

189425:PGRAT RS15035
gene id: 189425:PGRAT_RS15035
uniprot id: A0A089NIR2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

189425:PGRAT RS25805
gene id: 189425:PGRAT_RS25805
uniprot id: A0A089MAM9
names: Subcellular Location Annotation
messages: Membrane

189425:PGRAT RS25600
gene id: 189425:PGRAT_RS25600
uniprot id: A0A089MH68
names: Similarity
messages: Belongs to the PHP hydrolase family. HisK subfamily.

189425:PGRAT RS06280
gene id: 189425:PGRAT_RS06280
uniprot id: A0A089NEC4
names: Function
names: Subunit
messages: Catalyzes the conversion of a range of fructosamine 6-phosphates to glucose 6-phosphate and a free amino acid.
messages: Homooctamer.

189425:PGRAT RS09815
gene id: 189425:PGRAT_RS09815
uniprot id: A0A089NG34
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

189425:PGRAT RS12565
gene id: 189425:PGRAT_RS12565
uniprot id: A0A089M7Z1
names: Similarity
messages: Belongs to the UPF0473 family.

189425:PGRAT RS25990
gene id: 189425:PGRAT_RS25990
uniprot id: A0A089MAU0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TVP38/TMEM64 family.
messages: Cell membrane
messages: Membrane

189425:PGRAT RS02855
gene id: 189425:PGRAT_RS02855
uniprot id: A0A089M2U8
names: Similarity
messages: Belongs to the diacylglycerol/lipid kinase family.

189425:PGRAT RS11330
gene id: 189425:PGRAT_RS11330
uniprot id: A0A089M9P1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

189425:PGRAT RS20020
gene id: 189425:PGRAT_RS20020
uniprot id: A0A089MBV4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protease PrsW family.
messages: Cell membrane
messages: Involved in the degradation of specific anti-sigma factors.
messages: Membrane

189425:PGRAT RS27110
gene id: 189425:PGRAT_RS27110
uniprot id: A0A089MHT5
names: Function
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.
messages: Transcriptional repressor of xylose-utilizing enzymes.

189425:PGRAT RS00170
gene id: 189425:PGRAT_RS00170
uniprot id: A0A089NBH6
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.

189425:PGRAT RS26435
gene id: 189425:PGRAT_RS26435
uniprot id: A0A089NPI0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

189425:PGRAT RS23425
gene id: 189425:PGRAT_RS23425
uniprot id: A0A089MG47
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

189425:PGRAT RS23480
gene id: 189425:PGRAT_RS23480
uniprot id: A0A089NN19
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

189425:PGRAT RS25015
gene id: 189425:PGRAT_RS25015
uniprot id: A0A089MGV9
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

189425:PGRAT RS15305
gene id: 189425:PGRAT_RS15305
uniprot id: A0A089M6Y8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CotF family.
messages: Spore coat

189425:PGRAT RS10950
gene id: 189425:PGRAT_RS10950
uniprot id: A0A089M4M3
names: Similarity
messages: Belongs to the DCK/DGK family.

189425:PGRAT RS20240
gene id: 189425:PGRAT_RS20240
uniprot id: A0A089M9E4
names: Subcellular Location Annotation
messages: cell wall

189425:PGRAT RS16600
gene id: 189425:PGRAT_RS16600
uniprot id: A0A089MCJ4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase Z family.
messages: Binds 2 Zn(2+) ions.
messages: Counteracts the endogenous Pycsar antiviral defense system. Phosphodiesterase that enables metal-dependent hydrolysis of host cyclic nucleotide Pycsar defense signals such as cCMP and cUMP.
messages: Homodimer.
messages: Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA.

189425:PGRAT RS17765
gene id: 189425:PGRAT_RS17765
uniprot id: A0A089MDA3
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliG family.
messages: Membrane

189425:PGRAT RS20060
gene id: 189425:PGRAT_RS20060
uniprot id: A0A089MEF6
names: Function
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

189425:PGRAT RS01640
gene id: 189425:PGRAT_RS01640
uniprot id: A0A089M4U4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

189425:PGRAT RS26365
gene id: 189425:PGRAT_RS26365
uniprot id: A0A089MHK2
names: Similarity
messages: Belongs to the PspA/IM30 family.

189425:PGRAT RS16125
gene id: 189425:PGRAT_RS16125
uniprot id: A0A089M7B9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0053 family.
messages: Membrane

189425:PGRAT RS29400
gene id: 189425:PGRAT_RS29400
uniprot id: A0A089NQY5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Bcr/CmlA family.
messages: Belongs to the major facilitator superfamily. TCR/Tet family.
messages: Cell membrane
messages: Membrane

189425:PGRAT RS27030
gene id: 189425:PGRAT_RS27030
uniprot id: A0A089MCP5
names: Similarity
messages: Belongs to the peptidase C40 family.

189425:PGRAT RS21320
gene id: 189425:PGRAT_RS21320
uniprot id: A0A089MF20
names: Similarity
messages: Belongs to the glycosyl hydrolase 38 family.

189425:PGRAT RS14835
gene id: 189425:PGRAT_RS14835
uniprot id: A0A089MBQ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

189425:PGRAT RS01120
gene id: 189425:PGRAT_RS01120
uniprot id: A0A089M220
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

189425:PGRAT RS30540
gene id: 189425:PGRAT_RS30540
uniprot id: A0A089MEG5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the arabinose isomerase family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the conversion of L-arabinose to L-ribulose.

189425:PGRAT RS11100
gene id: 189425:PGRAT_RS11100
uniprot id: A0A089NGQ7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

189425:PGRAT RS29700
gene id: 189425:PGRAT_RS29700
uniprot id: A0A089MCJ1
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type B subfamily.
messages: Part of the 50S ribosomal subunit.

189425:PGRAT RS14610
gene id: 189425:PGRAT_RS14610
uniprot id: A0A089M4X6
names: Subcellular Location Annotation
messages: Membrane

189425:PGRAT RS11490
gene id: 189425:PGRAT_RS11490
uniprot id: A0A089NGX8
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

189425:PGRAT RS24275
gene id: 189425:PGRAT_RS24275
uniprot id: A0A089ME18
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YajC family.
messages: Membrane

189425:PGRAT RS28800
gene id: 189425:PGRAT_RS28800
uniprot id: A0A089MIS7
names: Subcellular Location Annotation
messages: Membrane

189425:PGRAT RS08735
gene id: 189425:PGRAT_RS08735
uniprot id: A0A089M1Y6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

189425:PGRAT RS24295
gene id: 189425:PGRAT_RS24295
uniprot id: A0A089NND6
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvB family.
messages: Cytoplasm
messages: Has 3 domains, the large (RuvB-L) and small ATPase (RuvB-S) domains and the C-terminal head (RuvB-H) domain. The head domain binds DNA, while the ATPase domains jointly bind ATP, ADP or are empty depending on the state of the subunit in the translocation cycle. During a single DNA translocation step the structure of each domain remains the same, but their relative positions change.
messages: Homohexamer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time. Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange. Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration. The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration. Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.

189425:PGRAT RS05565
gene id: 189425:PGRAT_RS05565
uniprot id: A0A089M6Q9
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

189425:PGRAT RS23355
gene id: 189425:PGRAT_RS23355
uniprot id: A0A089NN01
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

189425:PGRAT RS30240
gene id: 189425:PGRAT_RS30240
uniprot id: A0A089MCT2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0702 family.
messages: Cell membrane
messages: Membrane

189425:PGRAT RS08395
gene id: 189425:PGRAT_RS08395
uniprot id: A0A089M5S4
names: Similarity
messages: Belongs to the glycosyl hydrolase 3 family.

189425:PGRAT RS09100
gene id: 189425:PGRAT_RS09100
uniprot id: A0A089NFR8
names: Similarity
messages: Belongs to the shaker potassium channel beta subunit family.

189425:PGRAT RS08135
gene id: 189425:PGRAT_RS08135
uniprot id: A0A089M1N6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

189425:PGRAT RS00200
gene id: 189425:PGRAT_RS00200
uniprot id: A0A089M1G5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

189425:PGRAT RS11590
gene id: 189425:PGRAT_RS11590
uniprot id: A0A089M7E0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

189425:PGRAT RS00775
gene id: 189425:PGRAT_RS00775
uniprot id: A0A089M1R9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.

189425:PGRAT RS14525
gene id: 189425:PGRAT_RS14525
uniprot id: A0A089M8Y7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0324 family.
messages: Membrane

189425:PGRAT RS00460
gene id: 189425:PGRAT_RS00460
uniprot id: A0A089LZE5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2).
messages: Homodimer.

189425:PGRAT RS17945
gene id: 189425:PGRAT_RS17945
uniprot id: A0A089M8A1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

189425:PGRAT RS24005
gene id: 189425:PGRAT_RS24005
uniprot id: A0A089NN94
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

189425:PGRAT RS28610
gene id: 189425:PGRAT_RS28610
uniprot id: A0A089MC00
names: Similarity
messages: Belongs to the FlgM family.

189425:PGRAT RS02275
gene id: 189425:PGRAT_RS02275
uniprot id: A0A089LYL3
names: Similarity
messages: Belongs to the EamA transporter family.

189425:PGRAT RS13190
gene id: 189425:PGRAT_RS13190
uniprot id: A0A089M5S5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ribose 5-phosphate isomerase family.
messages: Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
messages: Homodimer.

189425:PGRAT RS10445
gene id: 189425:PGRAT_RS10445
uniprot id: A0A089M998
names: Similarity
messages: Belongs to the CAPAB/TerDEXZ family.

189425:PGRAT RS02575
gene id: 189425:PGRAT_RS02575
uniprot id: A0A089M0H2
names: Similarity
messages: Belongs to the antibiotic N-acetyltransferase family.

189425:PGRAT RS19190
gene id: 189425:PGRAT_RS19190
uniprot id: A0A089M7A4
names: Cofactor
messages: Binds 1 FAD per subunit.
messages: Binds 1 FMN per subunit.

189425:PGRAT RS01060
gene id: 189425:PGRAT_RS01060
uniprot id: A0A089NBX6
names: Similarity
messages: Belongs to the glycosyl hydrolase 130 family.

189425:PGRAT RS20965
gene id: 189425:PGRAT_RS20965
uniprot id: A0A089M894
names: Similarity
messages: In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.
messages: In the N-terminal section; belongs to the aldehyde dehydrogenase family.

189425:PGRAT RS17790
gene id: 189425:PGRAT_RS17790
uniprot id: A0A089MDA7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
messages: Belongs to the ClpX chaperone family. HslU subfamily.
messages: Cytoplasm

189425:PGRAT RS14685
gene id: 189425:PGRAT_RS14685
uniprot id: A0A089M924
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

189425:PGRAT RS17560
gene id: 189425:PGRAT_RS17560
uniprot id: A0A089MD70
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 3 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).
messages: Consists of three domains: the N-terminal catalytic domain, the anticodon-binding domain and the C-terminal extension.
messages: Cytoplasm
messages: Homodimer.

189425:PGRAT RS03245
gene id: 189425:PGRAT_RS03245
uniprot id: A0A089M331
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

189425:PGRAT RS21790
gene id: 189425:PGRAT_RS21790
uniprot id: A0A089MFB3
names: Function
names: Similarity
messages: Belongs to the LutA/YkgE family.
messages: Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source.

189425:PGRAT RS19845
gene id: 189425:PGRAT_RS19845
uniprot id: A0A089MBR6
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

189425:PGRAT RS20600
gene id: 189425:PGRAT_RS20600
uniprot id: A0A089MC71
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

189425:PGRAT RS02555
gene id: 189425:PGRAT_RS02555
uniprot id: A0A089M582
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

189425:PGRAT RS21695
gene id: 189425:PGRAT_RS21695
uniprot id: A0A089M8M5
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily.

189425:PGRAT RS16890
gene id: 189425:PGRAT_RS16890
uniprot id: A0A089MA71
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0756 family.
messages: Cell membrane

189425:PGRAT RS12720
gene id: 189425:PGRAT_RS12720
uniprot id: A0A089M3Y3
names: Similarity
messages: Belongs to the peptidase M29 family.

189425:PGRAT RS30385
gene id: 189425:PGRAT_RS30385
uniprot id: A0A089MJF5
names: Similarity
messages: Belongs to the MQO family.

189425:PGRAT RS27860
gene id: 189425:PGRAT_RS27860
uniprot id: A0A089MFP7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis. Some bacteria have evolved a zinc-coordinating structure that stabilizes the LID domain.
messages: Cytoplasm
messages: Monomer.

189425:PGRAT RS02320
gene id: 189425:PGRAT_RS02320
uniprot id: A0A089M2K1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

189425:PGRAT RS13345
gene id: 189425:PGRAT_RS13345
uniprot id: A0A089M5V3
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

189425:PGRAT RS01785
gene id: 189425:PGRAT_RS01785
uniprot id: A0A089NC82
names: Similarity
messages: Belongs to the peptidase S66 family.

189425:PGRAT RS07370
gene id: 189425:PGRAT_RS07370
uniprot id: A0A089NEV8
names: Similarity
messages: Belongs to the bacterial solute-binding protein 1 family.

189425:PGRAT RS04480
gene id: 189425:PGRAT_RS04480
uniprot id: A0A089M1H3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Ro 60 kDa family.
messages: Cytoplasm

189425:PGRAT RS07970
gene id: 189425:PGRAT_RS07970
uniprot id: A0A089M365
names: Similarity
messages: Belongs to the glycosyl hydrolase 36 family.

189425:PGRAT RS23415
gene id: 189425:PGRAT_RS23415
uniprot id: A0A089M9H8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane
messages: Membrane

189425:PGRAT RS17750
gene id: 189425:PGRAT_RS17750
uniprot id: A0A089MAR3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliJ family.
messages: Cell membrane
messages: Membrane

189425:PGRAT RS23450
gene id: 189425:PGRAT_RS23450
uniprot id: A0A089MG52
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MraZ family.
messages: Forms oligomers.
messages: nucleoid

189425:PGRAT RS27380
gene id: 189425:PGRAT_RS27380
uniprot id: A0A089MHY2
names: Cofactor
messages: Binds 2 manganese ions per subunit.

189425:PGRAT RS18735
gene id: 189425:PGRAT_RS18735
uniprot id: A0A089M8M2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

189425:PGRAT RS22055
gene id: 189425:PGRAT_RS22055
uniprot id: A0A089MCW9
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

189425:PGRAT RS20185
gene id: 189425:PGRAT_RS20185
uniprot id: A0A089M9D0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.
messages: Forms an icosahedral capsid composed of 60 subunits, arranged as a dodecamer of pentamers.

189425:PGRAT RS20710
gene id: 189425:PGRAT_RS20710
uniprot id: A0A089M852
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ArgR family.
messages: Cytoplasm
messages: Regulates arginine biosynthesis genes.

189425:PGRAT RS08630
gene id: 189425:PGRAT_RS08630
uniprot id: A0A089M1W6
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 51 family.
messages: Homohexamer; trimer of dimers.

189425:PGRAT RS08690
gene id: 189425:PGRAT_RS08690
uniprot id: A0A089M8D1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioester dehydratase family. FabZ subfamily.
messages: Cytoplasm
messages: Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.

189425:PGRAT RS28055
gene id: 189425:PGRAT_RS28055
uniprot id: A0A089MIA6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.

189425:PGRAT RS21230
gene id: 189425:PGRAT_RS21230
uniprot id: A0A089M8E2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
messages: Cytoplasm
messages: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.

189425:PGRAT RS00805
gene id: 189425:PGRAT_RS00805
uniprot id: A0A089LXV4
names: Similarity
messages: Belongs to the PHP hydrolase family. HisK subfamily.

189425:PGRAT RS28115
gene id: 189425:PGRAT_RS28115
uniprot id: A0A089MFV3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

189425:PGRAT RS17550
gene id: 189425:PGRAT_RS17550
uniprot id: A0A089M6J7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

189425:PGRAT RS16375
gene id: 189425:PGRAT_RS16375
uniprot id: A0A089M9X8
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

189425:PGRAT RS03585
gene id: 189425:PGRAT_RS03585
uniprot id: A0A089ND14
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

189425:PGRAT RS15520
gene id: 189425:PGRAT_RS15520
uniprot id: A0A089MC09
names: Subcellular Location Annotation
messages: Membrane

189425:PGRAT RS07145
gene id: 189425:PGRAT_RS07145
uniprot id: A0A089M7N4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Homodimer.

189425:PGRAT RS16395
gene id: 189425:PGRAT_RS16395
uniprot id: A0A089NJC2
names: Subcellular Location Annotation
messages: Membrane

189425:PGRAT RS02725
gene id: 189425:PGRAT_RS02725
uniprot id: A0A089LYT6
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

189425:PGRAT RS24200
gene id: 189425:PGRAT_RS24200
uniprot id: A0A089M9W1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

189425:PGRAT RS09565
gene id: 189425:PGRAT_RS09565
uniprot id: A0A089NG03
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
messages: Could methylate the ribose at the nucleotide 34 wobble position in tRNA.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

189425:PGRAT RS11815
gene id: 189425:PGRAT_RS11815
uniprot id: A0A089M9Z6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit A family.
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit B family.
messages: Cell membrane
messages: Membrane

189425:PGRAT RS07140
gene id: 189425:PGRAT_RS07140
uniprot id: A0A089M2T9
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

189425:PGRAT RS28490
gene id: 189425:PGRAT_RS28490
uniprot id: A0A089NQI2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

189425:PGRAT RS23200
gene id: 189425:PGRAT_RS23200
uniprot id: A0A089MAX1
names: Similarity
messages: Belongs to the glycosyl hydrolase 26 family.

189425:PGRAT RS30695
gene id: 189425:PGRAT_RS30695
uniprot id: A0A089MD21
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

189425:PGRAT RS11345
gene id: 189425:PGRAT_RS11345
uniprot id: A0A089M385
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

189425:PGRAT RS20980
gene id: 189425:PGRAT_RS20980
uniprot id: A0A089NLU0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

189425:PGRAT RS21220
gene id: 189425:PGRAT_RS21220
uniprot id: A0A089NLX2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

189425:PGRAT RS17715
gene id: 189425:PGRAT_RS17715
uniprot id: A0A089NK66
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliL family.
messages: Cell membrane
messages: Controls the rotational direction of flagella during chemotaxis.
messages: Membrane

189425:PGRAT RS21970
gene id: 189425:PGRAT_RS21970
uniprot id: A0A089MCV5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

189425:PGRAT RS26910
gene id: 189425:PGRAT_RS26910
uniprot id: A0A089MF95
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

189425:PGRAT RS28785
gene id: 189425:PGRAT_RS28785
uniprot id: A0A089MGA3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

189425:PGRAT RS00785
gene id: 189425:PGRAT_RS00785
uniprot id: A0A089LZK8
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

189425:PGRAT RS12870
gene id: 189425:PGRAT_RS12870
uniprot id: A0A089NHI1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

189425:PGRAT RS09180
gene id: 189425:PGRAT_RS09180
uniprot id: A0A089M3S6
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

189425:PGRAT RS25160
gene id: 189425:PGRAT_RS25160
uniprot id: A0A089MBT1
names: Similarity
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family.

189425:PGRAT RS13995
gene id: 189425:PGRAT_RS13995
uniprot id: A0A089M8N7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

189425:PGRAT RS23710
gene id: 189425:PGRAT_RS23710
uniprot id: A0A089MDR8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the flotillin-like FloA family.
messages: Cell membrane
messages: Found in functional membrane microdomains (FMM) that may be equivalent to eukaryotic membrane rafts FMMs are highly dynamic and increase in number as cells age. Flotillins are thought to be important factors in membrane fluidity.
messages: Homooligomerizes.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane raft

189425:PGRAT RS06565
gene id: 189425:PGRAT_RS06565
uniprot id: A0A089M7G3
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. SDR39U1 subfamily.

189425:PGRAT RS19535
gene id: 189425:PGRAT_RS19535
uniprot id: A0A089M7F7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Part of an ABC transporter complex involved in carbohydrate import. Could be involved in ribose, galactose and/or methyl galactoside import. Responsible for energy coupling to the transport system.

189425:PGRAT RS00880
gene id: 189425:PGRAT_RS00880
uniprot id: A0A089LXX5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

189425:PGRAT RS27265
gene id: 189425:PGRAT_RS27265
uniprot id: A0A089MBA7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

189425:PGRAT RS05500
gene id: 189425:PGRAT_RS05500
uniprot id: A0A089M478
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

189425:PGRAT RS18680
gene id: 189425:PGRAT_RS18680
uniprot id: A0A089M711
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

189425:PGRAT RS31035
gene id: 189425:PGRAT_RS31035
uniprot id: A0A089NRT3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A probable RNA chaperone. Forms a complex with KhpA which binds to cellular RNA and controls its expression. Plays a role in peptidoglycan (PG) homeostasis and cell length regulation.
messages: Belongs to the KhpB RNA-binding protein family.
messages: Cytoplasm
messages: Forms a complex with KhpA.
messages: Has an N-terminal Jag-N domain and 2 RNA-binding domains (KH and R3H).

189425:PGRAT RS01870
gene id: 189425:PGRAT_RS01870
uniprot id: A0A089M2C0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

189425:PGRAT RS14455
gene id: 189425:PGRAT_RS14455
uniprot id: A0A089M6F0
names: Subcellular Location Annotation
messages: Membrane

189425:PGRAT RS09695
gene id: 189425:PGRAT_RS09695
uniprot id: A0A089M8Z8
names: Cofactor
messages: Binds 2 magnesium ions per subunit.

189425:PGRAT RS19455
gene id: 189425:PGRAT_RS19455
uniprot id: A0A089MBI8
names: Similarity
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.

189425:PGRAT RS00760
gene id: 189425:PGRAT_RS00760
uniprot id: A0A089LZK2
names: Similarity
messages: Belongs to the 6-phosphogluconate dehydrogenase family.

189425:PGRAT RS00765
gene id: 189425:PGRAT_RS00765
uniprot id: A0A089M4C4
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. HisZ subfamily.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine.
messages: This function is generally fulfilled by the C-terminal part of HisG, which is missing in some bacteria such as this one.

189425:PGRAT RS01695
gene id: 189425:PGRAT_RS01695
uniprot id: A0A089NC70
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

189425:PGRAT RS31040
gene id: 189425:PGRAT_RS31040
uniprot id: A0A089MHC3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OXA1/ALB3/YidC family. Type 2 subfamily.
messages: Cell membrane
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins.

189425:PGRAT RS08070
gene id: 189425:PGRAT_RS08070
uniprot id: A0A089M5L6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

189425:PGRAT RS15370
gene id: 189425:PGRAT_RS15370
uniprot id: A0A089NIW1
names: Subcellular Location Annotation
messages: Membrane

189425:PGRAT RS21510
gene id: 189425:PGRAT_RS21510
uniprot id: A0A089M8J1
names: Function
messages: TetR is the repressor of the tetracycline resistance element; its N-terminal region forms a helix-turn-helix structure and binds DNA. Binding of tetracycline to TetR reduces the repressor affinity for the tetracycline resistance gene (tetA) promoter operator sites.

189425:PGRAT RS17130
gene id: 189425:PGRAT_RS17130
uniprot id: A0A089NJS6
names: Similarity
messages: Belongs to the 6-phosphogluconate dehydrogenase family.

189425:PGRAT RS19365
gene id: 189425:PGRAT_RS19365
uniprot id: A0A089NKY1
names: Similarity
messages: Belongs to the ABC transporter superfamily.

189425:PGRAT RS23665
gene id: 189425:PGRAT_RS23665
uniprot id: A0A089M9L6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer.

189425:PGRAT RS17530
gene id: 189425:PGRAT_RS17530
uniprot id: A0A089M838
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

189425:PGRAT RS17565
gene id: 189425:PGRAT_RS17565
uniprot id: A0A089NK43
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

189425:PGRAT RS09075
gene id: 189425:PGRAT_RS09075
uniprot id: A0A089NFR4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

189425:PGRAT RS24545
gene id: 189425:PGRAT_RS24545
uniprot id: A0A089MBI1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MinC family.
messages: Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization.
messages: Interacts with MinD and FtsZ.

189425:PGRAT RS31005
gene id: 189425:PGRAT_RS31005
uniprot id: A0A089MJU2
names: Similarity
messages: Belongs to the ParB family.

189425:PGRAT RS02935
gene id: 189425:PGRAT_RS02935
uniprot id: A0A089LYX9
names: Subcellular Location Annotation
messages: Membrane

189425:PGRAT RS28600
gene id: 189425:PGRAT_RS28600
uniprot id: A0A089NQK3
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the flagella basal body rod proteins family.
messages: Secreted

189425:PGRAT RS24080
gene id: 189425:PGRAT_RS24080
uniprot id: A0A089MGD6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

189425:PGRAT RS30750
gene id: 189425:PGRAT_RS30750
uniprot id: A0A089MH62
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

189425:PGRAT RS08400
gene id: 189425:PGRAT_RS08400
uniprot id: A0A089M1S1
names: Similarity
messages: Belongs to the glycosyl hydrolase 30 family.

189425:PGRAT RS08620
gene id: 189425:PGRAT_RS08620
uniprot id: A0A089NFI3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

189425:PGRAT RS27895
gene id: 189425:PGRAT_RS27895
uniprot id: A0A089MD38
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

189425:PGRAT RS22515
gene id: 189425:PGRAT_RS22515
uniprot id: A0A089MFM9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

189425:PGRAT RS33800
gene id: 189425:PGRAT_RS33800
uniprot id: A0A089MEI3
names: Similarity
messages: Belongs to the nitroreductase family.

189425:PGRAT RS03630
gene id: 189425:PGRAT_RS03630
uniprot id: A0A089M5W8
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.

189425:PGRAT RS16490
gene id: 189425:PGRAT_RS16490
uniprot id: A0A089M7H5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

189425:PGRAT RS31030
gene id: 189425:PGRAT_RS31030
uniprot id: A0A089MJU7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
messages: Binds 1 potassium ion per subunit.
messages: Cytoplasm
messages: Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

189425:PGRAT RS03595
gene id: 189425:PGRAT_RS03595
uniprot id: A0A089LZA5
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.

189425:PGRAT RS01335
gene id: 189425:PGRAT_RS01335
uniprot id: A0A089LZY7
names: Similarity
messages: Belongs to the polysaccharide synthase family.

189425:PGRAT RS29315
gene id: 189425:PGRAT_RS29315
uniprot id: A0A089NQX1
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

189425:PGRAT RS18640
gene id: 189425:PGRAT_RS18640
uniprot id: A0A089MDL0
names: Subcellular Location Annotation
messages: Membrane

189425:PGRAT RS26945
gene id: 189425:PGRAT_RS26945
uniprot id: A0A089MCN4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

189425:PGRAT RS11850
gene id: 189425:PGRAT_RS11850
uniprot id: A0A089M7I9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LTA synthase family.
messages: Cell membrane
messages: Membrane

189425:PGRAT RS20255
gene id: 189425:PGRAT_RS20255
uniprot id: A0A089MC24
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

189425:PGRAT RS00770
gene id: 189425:PGRAT_RS00770
uniprot id: A0A089NBR8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Lacks the C-terminal regulatory region which is replaced by HisZ.

189425:PGRAT RS24235
gene id: 189425:PGRAT_RS24235
uniprot id: A0A089MGG1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0702 family.
messages: Cell membrane
messages: Membrane

189425:PGRAT RS17690
gene id: 189425:PGRAT_RS17690
uniprot id: A0A089NK63
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliP/MopC/SpaP family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Plays a role in the flagellum-specific transport system.

189425:PGRAT RS28135
gene id: 189425:PGRAT_RS28135
uniprot id: A0A089NQA8
names: Activity Regulation
names: Caution
names: Function
names: Similarity
messages: Appears to be allosterically activated by the binding of pArg-containing polypeptides to the pArg-binding pocket localized in the C-terminal domain of McsB.
messages: Belongs to the ATP:guanido phosphotransferase family.
messages: Catalyzes the specific phosphorylation of arginine residues in proteins.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

189425:PGRAT RS24205
gene id: 189425:PGRAT_RS24205
uniprot id: A0A089MBC8
names: Similarity
messages: Belongs to the RecJ family.

189425:PGRAT RS23375
gene id: 189425:PGRAT_RS23375
uniprot id: A0A089MG38
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

189425:PGRAT RS13935
gene id: 189425:PGRAT_RS13935
uniprot id: A0A089MB47
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TmcAL family.
messages: Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of elongator tRNA(Met), using acetate and ATP as substrates. First activates an acetate ion to form acetyladenylate (Ac-AMP) and then transfers the acetyl group to tRNA to form ac(4)C34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

189425:PGRAT RS21950
gene id: 189425:PGRAT_RS21950
uniprot id: A0A089MA96
names: Similarity
messages: Belongs to the glycosyl hydrolase 30 family.

189425:PGRAT RS24690
gene id: 189425:PGRAT_RS24690
uniprot id: A0A089MBK6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm

189425:PGRAT RS15455
gene id: 189425:PGRAT_RS15455
uniprot id: A0A089M9G8
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

189425:PGRAT RS03990
gene id: 189425:PGRAT_RS03990
uniprot id: A0A089M195
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

189425:PGRAT RS19700
gene id: 189425:PGRAT_RS19700
uniprot id: A0A089ME76
names: Function
names: Similarity
messages: 3'-5' exonuclease.
messages: Belongs to the helicase family. DinG subfamily. Type 2 sub-subfamily.

189425:PGRAT RS24870
gene id: 189425:PGRAT_RS24870
uniprot id: A0A089MEB4
names: Similarity
messages: Belongs to the peptidase S16 family.

189425:PGRAT RS03825
gene id: 189425:PGRAT_RS03825
uniprot id: A0A089M625
names: Similarity
messages: Belongs to the heat shock protein 90 family.

189425:PGRAT RS13165
gene id: 189425:PGRAT_RS13165
uniprot id: A0A089M5S0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 3B subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

189425:PGRAT RS20115
gene id: 189425:PGRAT_RS20115
uniprot id: A0A089MEG8
names: Subcellular Location Annotation
messages: Membrane

189425:PGRAT RS07835
gene id: 189425:PGRAT_RS07835
uniprot id: A0A089M350
names: Function
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.
messages: Involved in some intermediate steps for the synthesis of the antibiotic polyketide bacillaene which is involved in secondary metabolism.

189425:PGRAT RS26330
gene id: 189425:PGRAT_RS26330
uniprot id: A0A089MAX7
names: Induction
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SspI family.
messages: Expressed only in the forespore compartment of sporulating cells.
messages: Spore core

189425:PGRAT RS01610
gene id: 189425:PGRAT_RS01610
uniprot id: A0A089M030
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KdgT transporter family.
messages: Catalyzes the proton-dependent uptake of 2-keto-3-deoxygluconate (KDG) into the cell.
messages: Cell membrane

189425:PGRAT RS24320
gene id: 189425:PGRAT_RS24320
uniprot id: A0A089MGH9
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TER reductase family.
messages: Involved in the fatty acid synthesis (FAS II). Catalyzes the reduction of a carbon-carbon double bond in an enoyl moiety that is covalently linked to a coenzyme A (CoA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

189425:PGRAT RS27855
gene id: 189425:PGRAT_RS27855
uniprot id: A0A089NQ39
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

189425:PGRAT RS08955
gene id: 189425:PGRAT_RS08955
uniprot id: A0A089M3N6
names: Similarity
messages: Belongs to the UPF0473 family.

189425:PGRAT RS23755
gene id: 189425:PGRAT_RS23755
uniprot id: A0A089NN62
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SbcD family.
messages: Heterodimer of SbcC and SbcD.
messages: SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity.

189425:PGRAT RS07830
gene id: 189425:PGRAT_RS07830
uniprot id: A0A089M1J4
names: Function
messages: Involved in some intermediate steps for the synthesis of the antibiotic polyketide bacillaene which is involved in secondary metabolism.

189425:PGRAT RS25920
gene id: 189425:PGRAT_RS25920
uniprot id: A0A089NPC6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

189425:PGRAT RS27890
gene id: 189425:PGRAT_RS27890
uniprot id: A0A089MBK8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

189425:PGRAT RS10260
gene id: 189425:PGRAT_RS10260
uniprot id: A0A089NGA9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccD/PCCB family.
messages: Binds 1 zinc ion per subunit.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

189425:PGRAT RS29635
gene id: 189425:PGRAT_RS29635
uniprot id: A0A089NR17
names: Similarity
messages: Belongs to the SIS family. PHI subfamily.

189425:PGRAT RS00315
gene id: 189425:PGRAT_RS00315
uniprot id: A0A089M443
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HSP33 family.
messages: Cytoplasm
messages: Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress.
messages: Under oxidizing conditions two disulfide bonds are formed involving the reactive cysteines. Under reducing conditions zinc is bound to the reactive cysteines and the protein is inactive.

189425:PGRAT RS21850
gene id: 189425:PGRAT_RS21850
uniprot id: A0A089NM92
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

189425:PGRAT RS06080
gene id: 189425:PGRAT_RS06080
uniprot id: A0A089M743
names: Similarity
messages: Belongs to the glycosyl hydrolase 39 family.

189425:PGRAT RS17635
gene id: 189425:PGRAT_RS17635
uniprot id: A0A089MD84
names: Function
names: Similarity
messages: Belongs to the CheD family.
messages: Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis.

189425:PGRAT RS09755
gene id: 189425:PGRAT_RS09755
uniprot id: A0A089NG28
names: Cofactor
names: Similarity
messages: Belongs to the glycosyl hydrolase 4 family.
messages: Binds 1 NAD(+) per subunit.

189425:PGRAT RS04980
gene id: 189425:PGRAT_RS04980
uniprot id: A0A089NDN2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
messages: Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).
messages: Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

189425:PGRAT RS30375
gene id: 189425:PGRAT_RS30375
uniprot id: A0A089MCV7
names: Similarity
messages: Belongs to the glycosyl hydrolase 68 family.

189425:PGRAT RS12235
gene id: 189425:PGRAT_RS12235
uniprot id: A0A089NHB1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

189425:PGRAT RS01215
gene id: 189425:PGRAT_RS01215
uniprot id: A0A089LY55
names: Similarity
messages: Belongs to the XFP family.

189425:PGRAT RS24915
gene id: 189425:PGRAT_RS24915
uniprot id: A0A089MGU4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PstS family.
messages: Cell membrane
messages: Involved in the system for phosphate transport across the cytoplasmic membrane.
messages: Membrane
messages: Part of the ABC transporter complex PstSACB involved in phosphate import.
messages: The complex is composed of two ATP-binding proteins (PstB), two transmembrane proteins (PstC and PstA) and a solute-binding protein (PstS).

189425:PGRAT RS26460
gene id: 189425:PGRAT_RS26460
uniprot id: A0A089MCI3
names: Subcellular Location Annotation
messages: Membrane

189425:PGRAT RS20955
gene id: 189425:PGRAT_RS20955
uniprot id: A0A089NLT5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.
messages: Belongs to the organic radical-activating enzymes family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm

189425:PGRAT RS20200
gene id: 189425:PGRAT_RS20200
uniprot id: A0A089MBZ8
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion.
messages: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.
messages: In the C-terminal section; belongs to the HTP reductase family.
messages: In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family.

189425:PGRAT RS27950
gene id: 189425:PGRAT_RS27950
uniprot id: A0A089MI82
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

189425:PGRAT RS19160
gene id: 189425:PGRAT_RS19160
uniprot id: A0A089M798
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

189425:PGRAT RS28355
gene id: 189425:PGRAT_RS28355
uniprot id: A0A089MIG9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvT family.
messages: The glycine cleavage system catalyzes the degradation of glycine.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

189425:PGRAT RS06730
gene id: 189425:PGRAT_RS06730
uniprot id: A0A089NEL3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NlpA lipoprotein family.
messages: Membrane

189425:PGRAT RS24460
gene id: 189425:PGRAT_RS24460
uniprot id: A0A089ME36
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. Homoserine kinase subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
messages: Cytoplasm

189425:PGRAT RS19205
gene id: 189425:PGRAT_RS19205
uniprot id: A0A089MDW9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

189425:PGRAT RS03770
gene id: 189425:PGRAT_RS03770
uniprot id: A0A089M3G7
names: Similarity
messages: Belongs to the diacylglycerol/lipid kinase family.

189425:PGRAT RS25660
gene id: 189425:PGRAT_RS25660
uniprot id: A0A089MC30
names: Subcellular Location Annotation
messages: Membrane

189425:PGRAT RS19910
gene id: 189425:PGRAT_RS19910
uniprot id: A0A089MEC4
names: Function
names: Similarity
messages: Belongs to the MqnA/MqnD family. MqnA subfamily.
messages: Catalyzes the dehydration of chorismate into 3-[(1-carboxyvinyl)oxy]benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2).

189425:PGRAT RS16050
gene id: 189425:PGRAT_RS16050
uniprot id: A0A089MC81
names: Cofactor
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.
messages: Binds 1 zinc ion per subunit.

189425:PGRAT RS24035
gene id: 189425:PGRAT_RS24035
uniprot id: A0A089MDX7
names: Subcellular Location Annotation
messages: Membrane

189425:PGRAT RS12890
gene id: 189425:PGRAT_RS12890
uniprot id: A0A089MAM8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

189425:PGRAT RS03615
gene id: 189425:PGRAT_RS03615
uniprot id: A0A089M3A2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FGAMS family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

189425:PGRAT RS26205
gene id: 189425:PGRAT_RS26205
uniprot id: A0A089NPF2
names: Subcellular Location Annotation
messages: Membrane

189425:PGRAT RS14055
gene id: 189425:PGRAT_RS14055
uniprot id: A0A089M671
names: Subcellular Location Annotation
messages: Cytoplasm

189425:PGRAT RS04745
gene id: 189425:PGRAT_RS04745
uniprot id: A0A089M1K9
names: Similarity
messages: Belongs to the CdaR family.

189425:PGRAT RS16160
gene id: 189425:PGRAT_RS16160
uniprot id: A0A089NJ76
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by fructose 1,6-bisphosphate (FBP).
messages: Belongs to the LDH/MDH superfamily. LDH family.
messages: Catalyzes the conversion of lactate to pyruvate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

189425:PGRAT RS18025
gene id: 189425:PGRAT_RS18025
uniprot id: A0A089MDE3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPF0173 family.
messages: Counteracts the endogenous Pycsar antiviral defense system. Phosphodiesterase that enables metal-dependent hydrolysis of host cyclic nucleotide Pycsar defense signals such as cCMP and cUMP.
messages: Homodimer.

189425:PGRAT RS16010
gene id: 189425:PGRAT_RS16010
uniprot id: A0A089M5M9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PstS family.
messages: Cell membrane
messages: Involved in the system for phosphate transport across the cytoplasmic membrane.
messages: Membrane
messages: Part of the ABC transporter complex PstSACB involved in phosphate import.
messages: The complex is composed of two ATP-binding proteins (PstB), two transmembrane proteins (PstC and PstA) and a solute-binding protein (PstS).

189425:PGRAT RS06315
gene id: 189425:PGRAT_RS06315
uniprot id: A0A089M0R8
names: Similarity
messages: Belongs to the glycerate kinase type-1 family.

189425:PGRAT RS02635
gene id: 189425:PGRAT_RS02635
uniprot id: A0A089M0I0
names: Similarity
messages: Belongs to the UPF0045 family.

189425:PGRAT RS05635
gene id: 189425:PGRAT_RS05635
uniprot id: A0A089M1Y8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Forms a complex with TatC.
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.

189425:PGRAT RS06415
gene id: 189425:PGRAT_RS06415
uniprot id: A0A089NEE9
names: Subcellular Location Annotation
messages: Membrane

189425:PGRAT RS20920
gene id: 189425:PGRAT_RS20920
uniprot id: A0A089M9T2
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.

189425:PGRAT RS01185
gene id: 189425:PGRAT_RS01185
uniprot id: A0A089M227
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

189425:PGRAT RS05005
gene id: 189425:PGRAT_RS05005
uniprot id: A0A089NDN6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

189425:PGRAT RS04995
gene id: 189425:PGRAT_RS04995
uniprot id: A0A089M1P1
names: Subcellular Location Annotation
messages: Membrane

189425:PGRAT RS17525
gene id: 189425:PGRAT_RS17525
uniprot id: A0A089M6I3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

189425:PGRAT RS19825
gene id: 189425:PGRAT_RS19825
uniprot id: A0A089M7L9
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

189425:PGRAT RS15365
gene id: 189425:PGRAT_RS15365
uniprot id: A0A089MBZ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

189425:PGRAT RS06575
gene id: 189425:PGRAT_RS06575
uniprot id: A0A089M4Y5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the AP endonuclease 2 family.
messages: Binds 3 Zn(2+) ions.
messages: Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate.

189425:PGRAT RS21745
gene id: 189425:PGRAT_RS21745
uniprot id: A0A089NM72
names: Similarity
messages: Belongs to the UPF0312 family.

189425:PGRAT RS10300
gene id: 189425:PGRAT_RS10300
uniprot id: A0A089M4D4
names: Similarity
messages: Belongs to the citrate synthase family.

189425:PGRAT RS23885
gene id: 189425:PGRAT_RS23885
uniprot id: A0A089MB70
names: Subcellular Location Annotation
messages: Membrane

189425:PGRAT RS00030
gene id: 189425:PGRAT_RS00030
uniprot id: A0A089M1C9
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Binds two Mg(2+) per subunit. The magnesium ions form salt bridges with both the protein and the DNA. Can also accept other divalent metal cations, such as Mn(2+) or Ca(2+).
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

189425:PGRAT RS20610
gene id: 189425:PGRAT_RS20610
uniprot id: A0A089M9N0
names: Function
names: Similarity
messages: Belongs to the BCKDHA family.
messages: The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3).

189425:PGRAT RS16000
gene id: 189425:PGRAT_RS16000
uniprot id: A0A089NJ48
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane

189425:PGRAT RS08050
gene id: 189425:PGRAT_RS08050
uniprot id: A0A089M1M3
names: Similarity
messages: Belongs to the transposase 11 family.

189425:PGRAT RS23655
gene id: 189425:PGRAT_RS23655
uniprot id: A0A089NN44
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

189425:PGRAT RS21255
gene id: 189425:PGRAT_RS21255
uniprot id: A0A089M8E7
names: Similarity
messages: Belongs to the manganese catalase family.

189425:PGRAT RS10295
gene id: 189425:PGRAT_RS10295
uniprot id: A0A089M2R7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

189425:PGRAT RS14175
gene id: 189425:PGRAT_RS14175
uniprot id: A0A089M4P8
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

189425:PGRAT RS08580
gene id: 189425:PGRAT_RS08580
uniprot id: A0A089M1V3
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

189425:PGRAT RS28350
gene id: 189425:PGRAT_RS28350
uniprot id: A0A089MDC7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: Is also involved in protein lipoylation via its role as an octanoyl/lipoyl carrier protein intermediate.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

189425:PGRAT RS31000
gene id: 189425:PGRAT_RS31000
uniprot id: A0A089MEP0
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.

189425:PGRAT RS21550
gene id: 189425:PGRAT_RS21550
uniprot id: A0A089NM35
names: Subcellular Location Annotation
messages: Membrane

189425:PGRAT RS03520
gene id: 189425:PGRAT_RS03520
uniprot id: A0A089ND04
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

189425:PGRAT RS22045
gene id: 189425:PGRAT_RS22045
uniprot id: A0A089MFF8
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

189425:PGRAT RS29395
gene id: 189425:PGRAT_RS29395
uniprot id: A0A089MJ12
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LPG synthase family.
messages: Catalyzes the transfer of a lysyl group from L-lysyl-tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms.
messages: Cell membrane
messages: Membrane

189425:PGRAT RS16450
gene id: 189425:PGRAT_RS16450
uniprot id: A0A089M9Z3
names: Similarity
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Spore germination protein (SGP) (TC 2.A.3.9) family.

189425:PGRAT RS17380
gene id: 189425:PGRAT_RS17380
uniprot id: A0A089M7Y9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase Y family.
messages: Cell membrane
messages: Endoribonuclease that initiates mRNA decay.

189425:PGRAT RS03140
gene id: 189425:PGRAT_RS03140
uniprot id: A0A089NCT9
names: Subcellular Location Annotation
messages: Membrane

189425:PGRAT RS00810
gene id: 189425:PGRAT_RS00810
uniprot id: A0A089LZL6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

189425:PGRAT RS19115
gene id: 189425:PGRAT_RS19115
uniprot id: A0A089M8T3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

189425:PGRAT RS01180
gene id: 189425:PGRAT_RS01180
uniprot id: A0A089NBZ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

189425:PGRAT RS11105
gene id: 189425:PGRAT_RS11105
uniprot id: A0A089M747
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily.

189425:PGRAT RS16175
gene id: 189425:PGRAT_RS16175
uniprot id: A0A089M5Q7
names: Subcellular Location Annotation
messages: Membrane

189425:PGRAT RS03605
gene id: 189425:PGRAT_RS03605
uniprot id: A0A089M5W3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PurS family.
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

189425:PGRAT RS10365
gene id: 189425:PGRAT_RS10365
uniprot id: A0A089NGC9
names: Subcellular Location Annotation
messages: Membrane

189425:PGRAT RS07910
gene id: 189425:PGRAT_RS07910
uniprot id: A0A089M1K1
names: Similarity
messages: Belongs to the glycosyl hydrolase 36 family.

189425:PGRAT RS03305
gene id: 189425:PGRAT_RS03305
uniprot id: A0A089M340
names: Subcellular Location Annotation
messages: Membrane

189425:PGRAT RS07275
gene id: 189425:PGRAT_RS07275
uniprot id: A0A089M1A6
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the gamma-glutamyltransferase family.
messages: Cleaved by autocatalysis into a large and a small subunit.
messages: This enzyme consists of two polypeptide chains, which are synthesized in precursor form from a single polypeptide.

189425:PGRAT RS14965
gene id: 189425:PGRAT_RS14965
uniprot id: A0A089M562
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

189425:PGRAT RS23980
gene id: 189425:PGRAT_RS23980
uniprot id: A0A089NN90
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Autoproteolytically processed. The inactive tetrameric zymogen termed p46 autoprocesses to a smaller form termed p41, which is active only during spore germination.
messages: Belongs to the peptidase A25 family.
messages: Homotetramer.
messages: Initiates the rapid degradation of small, acid-soluble proteins during spore germination.

189425:PGRAT RS24745
gene id: 189425:PGRAT_RS24745
uniprot id: A0A089MBL6
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

189425:PGRAT RS09810
gene id: 189425:PGRAT_RS09810
uniprot id: A0A089M914
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

189425:PGRAT RS23760
gene id: 189425:PGRAT_RS23760
uniprot id: A0A089MDS9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. AddA subfamily.
messages: Heterodimer of AddA and AddB/RexB.
messages: The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domain is required for chi fragment generation; this subunit has the helicase and 3' -> 5' nuclease activities.

189425:PGRAT RS25645
gene id: 189425:PGRAT_RS25645
uniprot id: A0A089NP56
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

189425:PGRAT RS30855
gene id: 189425:PGRAT_RS30855
uniprot id: A0A089NRP2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S1C family.
messages: Cell membrane
messages: Membrane

189425:PGRAT RS17555
gene id: 189425:PGRAT_RS17555
uniprot id: A0A089M843
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-C family. PolC subfamily.
messages: Cytoplasm
messages: Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

189425:PGRAT RS02610
gene id: 189425:PGRAT_RS02610
uniprot id: A0A089M0H6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.
messages: Binds 2 iron ions per subunit.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

189425:PGRAT RS12230
gene id: 189425:PGRAT_RS12230
uniprot id: A0A089MAD0
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

189425:PGRAT RS07535
gene id: 189425:PGRAT_RS07535
uniprot id: A0A089M308
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

189425:PGRAT RS16380
gene id: 189425:PGRAT_RS16380
uniprot id: A0A089M5U1
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.
messages: Synthesizes alpha-1,4-glucan chains using ADP-glucose.

189425:PGRAT RS25080
gene id: 189425:PGRAT_RS25080
uniprot id: A0A089MGX0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

189425:PGRAT RS09110
gene id: 189425:PGRAT_RS09110
uniprot id: A0A089M268
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. GalK subfamily.
messages: Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P).
messages: Cytoplasm

189425:PGRAT RS11400
gene id: 189425:PGRAT_RS11400
uniprot id: A0A089M4U9
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peroxiredoxin family. Tpx subfamily.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

189425:PGRAT RS28000
gene id: 189425:PGRAT_RS28000
uniprot id: A0A089MD54
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

189425:PGRAT RS25825
gene id: 189425:PGRAT_RS25825
uniprot id: A0A089MEW3
names: Similarity
messages: Belongs to the transpeptidase family.

189425:PGRAT RS15600
gene id: 189425:PGRAT_RS15600
uniprot id: A0A089M5E9
names: Similarity
messages: Belongs to the PHP hydrolase family. HisK subfamily.

189425:PGRAT RS20100
gene id: 189425:PGRAT_RS20100
uniprot id: A0A089MBX3
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Activated by phosphorylation and inhibited by fructose 1,6-bisphosphate (FBP).
messages: Belongs to the FGGY kinase family.
messages: Homotetramer and homodimer (in equilibrium).
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

189425:PGRAT RS00165
gene id: 189425:PGRAT_RS00165
uniprot id: A0A089M409
names: Similarity
messages: Belongs to the alpha/beta-type SASP family.

189425:PGRAT RS05855
gene id: 189425:PGRAT_RS05855
uniprot id: A0A089NE47
names: Similarity
messages: Belongs to the FBPase class 2 family.

189425:PGRAT RS23470
gene id: 189425:PGRAT_RS23470
uniprot id: A0A089MB09
names: Similarity
messages: Belongs to the ABC transporter superfamily.

189425:PGRAT RS11125
gene id: 189425:PGRAT_RS11125
uniprot id: A0A089NGR2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

189425:PGRAT RS01775
gene id: 189425:PGRAT_RS01775
uniprot id: A0A089M052
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

189425:PGRAT RS00295
gene id: 189425:PGRAT_RS00295
uniprot id: A0A089NBJ7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the quinolinate synthase family. Type 2 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
messages: Cytoplasm

189425:PGRAT RS05320
gene id: 189425:PGRAT_RS05320
uniprot id: A0A089M058
names: Similarity
messages: Belongs to the bacterial sugar transferase family.

189425:PGRAT RS27515
gene id: 189425:PGRAT_RS27515
uniprot id: A0A089MBF3
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

189425:PGRAT RS17580
gene id: 189425:PGRAT_RS17580
uniprot id: A0A089M846
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.

189425:PGRAT RS13260
gene id: 189425:PGRAT_RS13260
uniprot id: A0A089M898
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

189425:PGRAT RS03640
gene id: 189425:PGRAT_RS03640
uniprot id: A0A089M3A8
names: Similarity
messages: Belongs to the GARS family.

189425:PGRAT RS25485
gene id: 189425:PGRAT_RS25485
uniprot id: A0A089MAH4
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.

189425:PGRAT RS06530
gene id: 189425:PGRAT_RS06530
uniprot id: A0A089M0Y3
names: Subcellular Location Annotation
messages: Membrane

189425:PGRAT RS17035
gene id: 189425:PGRAT_RS17035
uniprot id: A0A089M657
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methylthiotransferase family. MiaB subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
messages: Cytoplasm
messages: Monomer.

189425:PGRAT RS07775
gene id: 189425:PGRAT_RS07775
uniprot id: A0A089M7W6
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

189425:PGRAT RS08835
gene id: 189425:PGRAT_RS08835
uniprot id: A0A089NFM1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

189425:PGRAT RS09060
gene id: 189425:PGRAT_RS09060
uniprot id: A0A089M255
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

189425:PGRAT RS13115
gene id: 189425:PGRAT_RS13115
uniprot id: A0A089MAQ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PrsA family.
messages: Cell membrane
messages: Membrane
messages: Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins.

189425:PGRAT RS15180
gene id: 189425:PGRAT_RS15180
uniprot id: A0A089M6X1
names: Subcellular Location Annotation
messages: Membrane

189425:PGRAT RS16510
gene id: 189425:PGRAT_RS16510
uniprot id: A0A089M5W5
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

189425:PGRAT RS28780
gene id: 189425:PGRAT_RS28780
uniprot id: A0A089NQQ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase delta chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

189425:PGRAT RS06035
gene id: 189425:PGRAT_RS06035
uniprot id: A0A089NE82
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

189425:PGRAT RS07430
gene id: 189425:PGRAT_RS07430
uniprot id: A0A089M1D5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

189425:PGRAT RS23320
gene id: 189425:PGRAT_RS23320
uniprot id: A0A089MAY6
names: Subcellular Location Annotation
messages: Cytoplasm

189425:PGRAT RS22325
gene id: 189425:PGRAT_RS22325
uniprot id: A0A089MAF6
names: Similarity
messages: Belongs to the UPF0758 family.

189425:PGRAT RS09820
gene id: 189425:PGRAT_RS09820
uniprot id: A0A089M6I6
names: Function
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.
messages: Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine.

189425:PGRAT RS22600
gene id: 189425:PGRAT_RS22600
uniprot id: A0A089MFP0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

189425:PGRAT RS06040
gene id: 189425:PGRAT_RS06040
uniprot id: A0A089M4J2
names: Similarity
messages: Belongs to the bacterial solute-binding protein 1 family.

189425:PGRAT RS03155
gene id: 189425:PGRAT_RS03155
uniprot id: A0A089M0R9
names: Similarity
messages: Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.

189425:PGRAT RS02410
gene id: 189425:PGRAT_RS02410
uniprot id: A0A089M0F1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

189425:PGRAT RS12975
gene id: 189425:PGRAT_RS12975
uniprot id: A0A089NHJ7
names: Subcellular Location Annotation
messages: Membrane

189425:PGRAT RS29640
gene id: 189425:PGRAT_RS29640
uniprot id: A0A089MGM1
names: Similarity
messages: Belongs to the HPS/KGPDC family. HPS subfamily.

189425:PGRAT RS25050
gene id: 189425:PGRAT_RS25050
uniprot id: A0A089MGW4
names: Subcellular Location Annotation
messages: Membrane

189425:PGRAT RS09460
gene id: 189425:PGRAT_RS09460
uniprot id: A0A089NFZ0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MetA family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.

189425:PGRAT RS13040
gene id: 189425:PGRAT_RS13040
uniprot id: A0A089M440
names: Subcellular Location Annotation
messages: Membrane

189425:PGRAT RS24285
gene id: 189425:PGRAT_RS24285
uniprot id: A0A089MBE2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

189425:PGRAT RS12800
gene id: 189425:PGRAT_RS12800
uniprot id: A0A089M3Z5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

189425:PGRAT RS19250
gene id: 189425:PGRAT_RS19250
uniprot id: A0A089NKV8
names: Similarity
messages: Belongs to the UPF0237 family.

189425:PGRAT RS14240
gene id: 189425:PGRAT_RS14240
uniprot id: A0A089MBC4
names: Similarity
messages: Belongs to the GerABKC lipoprotein family.

189425:PGRAT RS20775
gene id: 189425:PGRAT_RS20775
uniprot id: A0A089NLR2
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

189425:PGRAT RS25595
gene id: 189425:PGRAT_RS25595
uniprot id: A0A089MC20
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

189425:PGRAT RS30030
gene id: 189425:PGRAT_RS30030
uniprot id: A0A089ME73
names: Similarity
messages: Belongs to the YjdM family.

189425:PGRAT RS02285
gene id: 189425:PGRAT_RS02285
uniprot id: A0A089M538
names: Similarity
messages: Belongs to the flavin oxidoreductase frp family.

189425:PGRAT RS23605
gene id: 189425:PGRAT_RS23605
uniprot id: A0A089NN36
names: Similarity
messages: Belongs to the peptidase S8 family.

189425:PGRAT RS19580
gene id: 189425:PGRAT_RS19580
uniprot id: A0A089NL25
names: Similarity
messages: Belongs to the AHA1 family.

189425:PGRAT RS23330
gene id: 189425:PGRAT_RS23330
uniprot id: A0A089NMZ7
names: Similarity
messages: Belongs to the YggT family.

189425:PGRAT RS28500
gene id: 189425:PGRAT_RS28500
uniprot id: A0A089MBX6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

189425:PGRAT RS17830
gene id: 189425:PGRAT_RS17830
uniprot id: A0A089M6N6
names: Similarity
messages: Belongs to the OsmC/Ohr family.

189425:PGRAT RS11840
gene id: 189425:PGRAT_RS11840
uniprot id: A0A089MA02
names: Similarity
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit G family.

189425:PGRAT RS04535
gene id: 189425:PGRAT_RS04535
uniprot id: A0A089M6B1
names: Similarity
messages: Belongs to the glycosyl hydrolase 38 family.

189425:PGRAT RS12280
gene id: 189425:PGRAT_RS12280
uniprot id: A0A089M5D6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

189425:PGRAT RS21090
gene id: 189425:PGRAT_RS21090
uniprot id: A0A089MEZ1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 independent methionine synthase family.
messages: Binds 1 zinc ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine resulting in methionine formation.

189425:PGRAT RS18895
gene id: 189425:PGRAT_RS18895
uniprot id: A0A089M8P9
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

189425:PGRAT RS23280
gene id: 189425:PGRAT_RS23280
uniprot id: A0A089NMZ2
names: Function
names: Similarity
names: Subunit
messages: Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily.
messages: Homodimer and homohexamer; in equilibrium.
messages: Regulates transcriptional attenuation of the pyrimidine nucleotide (pyr) operon by binding in a uridine-dependent manner to specific sites on pyr mRNA. This disrupts an antiterminator hairpin in the RNA and favors formation of a downstream transcription terminator, leading to a reduced expression of downstream genes.

189425:PGRAT RS22615
gene id: 189425:PGRAT_RS22615
uniprot id: A0A089MD65
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

189425:PGRAT RS09895
gene id: 189425:PGRAT_RS09895
uniprot id: A0A089M6J3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0053 family.
messages: Membrane

189425:PGRAT RS04170
gene id: 189425:PGRAT_RS04170
uniprot id: A0A089M1C2
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

189425:PGRAT RS28005
gene id: 189425:PGRAT_RS28005
uniprot id: A0A089MI94
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

189425:PGRAT RS30950
gene id: 189425:PGRAT_RS30950
uniprot id: A0A089MJS9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein bS6.

189425:PGRAT RS05580
gene id: 189425:PGRAT_RS05580
uniprot id: A0A089M0A5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic Ku family.
messages: Homodimer. Interacts with LigD.
messages: With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD.

189425:PGRAT RS26550
gene id: 189425:PGRAT_RS26550
uniprot id: A0A089MHM4
names: Similarity
messages: Belongs to the BMP lipoprotein family.

189425:PGRAT RS12060
gene id: 189425:PGRAT_RS12060
uniprot id: A0A089NH69
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

189425:PGRAT RS17070
gene id: 189425:PGRAT_RS17070
uniprot id: A0A089MCT5
names: Similarity
messages: Belongs to the UPF0597 family.

189425:PGRAT RS24300
gene id: 189425:PGRAT_RS24300
uniprot id: A0A089ME22
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvA family.
messages: Cytoplasm
messages: Has three domains with a flexible linker between the domains II and III and assumes an 'L' shape. Domain III is highly mobile and contacts RuvB.
messages: Homotetramer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

189425:PGRAT RS07005
gene id: 189425:PGRAT_RS07005
uniprot id: A0A089M2R9
names: Similarity
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Spore germination protein (SGP) (TC 2.A.3.9) family.

189425:PGRAT RS07380
gene id: 189425:PGRAT_RS07380
uniprot id: A0A089M1C6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

189425:PGRAT RS19715
gene id: 189425:PGRAT_RS19715
uniprot id: A0A089M7J6
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

189425:PGRAT RS04365
gene id: 189425:PGRAT_RS04365
uniprot id: A0A089NDE2
names: Similarity
messages: Belongs to the ABC transporter superfamily.

189425:PGRAT RS09860
gene id: 189425:PGRAT_RS09860
uniprot id: A0A089M920
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

189425:PGRAT RS16060
gene id: 189425:PGRAT_RS16060
uniprot id: A0A089M9R9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
messages: Cytoplasm

189425:PGRAT RS30865
gene id: 189425:PGRAT_RS30865
uniprot id: A0A089MD51
names: Function
names: Subunit
messages: Counteracts the endogenous Pycsar antiviral defense system. Phosphodiesterase that enables metal-dependent hydrolysis of host cyclic nucleotide Pycsar defense signals such as cCMP and cUMP.
messages: Homodimer.

189425:PGRAT RS09275
gene id: 189425:PGRAT_RS09275
uniprot id: A0A089M8Q2
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

189425:PGRAT RS28960
gene id: 189425:PGRAT_RS28960
uniprot id: A0A089MDR5
names: Subcellular Location Annotation
messages: Membrane

189425:PGRAT RS11960
gene id: 189425:PGRAT_RS11960
uniprot id: A0A089NH52
names: Subcellular Location Annotation
messages: Membrane

189425:PGRAT RS06865
gene id: 189425:PGRAT_RS06865
uniprot id: A0A089M140
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0060 family.
messages: Cell membrane

189425:PGRAT RS28040
gene id: 189425:PGRAT_RS28040
uniprot id: A0A089MFT6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

189425:PGRAT RS08430
gene id: 189425:PGRAT_RS08430
uniprot id: A0A089M3D6
names: Similarity
messages: Belongs to the glycosyl hydrolase 42 family.

189425:PGRAT RS15715
gene id: 189425:PGRAT_RS15715
uniprot id: A0A089MC31
names: Function
names: Similarity
names: Subunit
messages: Counteracts the endogenous Pycsar antiviral defense system. Phosphodiesterase that enables metal-dependent hydrolysis of host cyclic nucleotide Pycsar defense signals such as cCMP and cUMP.
messages: Homodimer.
messages: In the N-terminal section; belongs to the zinc metallo-hydrolase group 3 family.

189425:PGRAT RS04790
gene id: 189425:PGRAT_RS04790
uniprot id: A0A089M3V2
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.

189425:PGRAT RS08950
gene id: 189425:PGRAT_RS08950
uniprot id: A0A089M229
names: Similarity
messages: Belongs to the UPF0473 family.

189425:PGRAT RS02190
gene id: 189425:PGRAT_RS02190
uniprot id: A0A089NCE6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 1 lipoyl cofactor covalently.
messages: E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).
messages: Forms a 24-polypeptide structural core with octahedral symmetry. Part of the 2-oxoglutarate dehydrogenase (OGDH) complex composed of E1 (2-oxoglutarate dehydrogenase), E2 (dihydrolipoamide succinyltransferase) and E3 (dihydrolipoamide dehydrogenase); the complex contains multiple copies of the three enzymatic components (E1, E2 and E3).

189425:PGRAT RS20695
gene id: 189425:PGRAT_RS20695
uniprot id: A0A089MEU2
names: Cofactor
names: Function
names: Subcellular Location Annotation
messages: Binds 1 Ca(2+) ion per subunit.
messages: Cytoplasm
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with Spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. Repressor of abrB, activator of the spoIIa operon. Binds the DNA sequence 5'-TGNCGAA-3' (0A box).
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

189425:PGRAT RS25385
gene id: 189425:PGRAT_RS25385
uniprot id: A0A089NP07
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

189425:PGRAT RS28270
gene id: 189425:PGRAT_RS28270
uniprot id: A0A089MDB0
names: Similarity
messages: Belongs to the ABC transporter superfamily.

189425:PGRAT RS23810
gene id: 189425:PGRAT_RS23810
uniprot id: A0A089MDT7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. PrmA family.
messages: Cytoplasm
messages: Methylates ribosomal protein L11.

189425:PGRAT RS23800
gene id: 189425:PGRAT_RS23800
uniprot id: A0A089MGA2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

189425:PGRAT RS11950
gene id: 189425:PGRAT_RS11950
uniprot id: A0A089M545
names: Similarity
messages: Belongs to the nitroreductase family.

189425:PGRAT RS17705
gene id: 189425:PGRAT_RS17705
uniprot id: A0A089M862
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliN/MopA/SpaO family.
messages: Membrane

189425:PGRAT RS20755
gene id: 189425:PGRAT_RS20755
uniprot id: A0A089MC90
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

189425:PGRAT RS00570
gene id: 189425:PGRAT_RS00570
uniprot id: A0A089M498
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

189425:PGRAT RS26335
gene id: 189425:PGRAT_RS26335
uniprot id: A0A089MCG8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
messages: Cytoplasm
messages: Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.

189425:PGRAT RS10595
gene id: 189425:PGRAT_RS10595
uniprot id: A0A089M6U9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

189425:PGRAT RS22040
gene id: 189425:PGRAT_RS22040
uniprot id: A0A089MAA8
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

189425:PGRAT RS14305
gene id: 189425:PGRAT_RS14305
uniprot id: A0A089M8U5
names: Subcellular Location Annotation
messages: Membrane

189425:PGRAT RS22635
gene id: 189425:PGRAT_RS22635
uniprot id: A0A089NMN7
names: Similarity
messages: Belongs to the glycosyl hydrolase 36 family.

189425:PGRAT RS21530
gene id: 189425:PGRAT_RS21530
uniprot id: A0A089MCM1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

189425:PGRAT RS19730
gene id: 189425:PGRAT_RS19730
uniprot id: A0A089ME83
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

189425:PGRAT RS22310
gene id: 189425:PGRAT_RS22310
uniprot id: A0A089NMI1
names: Similarity
messages: Belongs to the GSP E family.

189425:PGRAT RS09040
gene id: 189425:PGRAT_RS09040
uniprot id: A0A089M8K7
names: Similarity
messages: Belongs to the glycosyl hydrolase 130 family.

189425:PGRAT RS06920
gene id: 189425:PGRAT_RS06920
uniprot id: A0A089M146
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the RtcB family.
messages: Binds 2 manganese ions per subunit.
messages: Monomer.

189425:PGRAT RS29610
gene id: 189425:PGRAT_RS29610
uniprot id: A0A089MCH5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M20B family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Cleaves the N-terminal amino acid of tripeptides.
messages: Cytoplasm

189425:PGRAT RS16735
gene id: 189425:PGRAT_RS16735
uniprot id: A0A089MA48
names: Similarity
messages: Belongs to the glutamine synthetase family.

189425:PGRAT RS06755
gene id: 189425:PGRAT_RS06755
uniprot id: A0A089NEL7
names: Function
names: Similarity
messages: Belongs to the PNP/UDP phosphorylase family. MtnN subfamily.
messages: Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively. Also cleaves 5'-deoxyadenosine, a toxic by-product of radical S-adenosylmethionine (SAM) enzymes, into 5-deoxyribose and adenine.

189425:PGRAT RS02870
gene id: 189425:PGRAT_RS02870
uniprot id: A0A089M5E6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 2 family.
messages: Binds a copper A center.
messages: Cell membrane
messages: Membrane
messages: Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B).

189425:PGRAT RS03150
gene id: 189425:PGRAT_RS03150
uniprot id: A0A089LZ25
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
messages: Homotetramer.
messages: Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc.

189425:PGRAT RS21570
gene id: 189425:PGRAT_RS21570
uniprot id: A0A089MF68
names: Function
names: Subunit
messages: Catalyzes the conversion of a range of fructosamine 6-phosphates to glucose 6-phosphate and a free amino acid.
messages: Homooctamer.

189425:PGRAT RS19905
gene id: 189425:PGRAT_RS19905
uniprot id: A0A089M976
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

189425:PGRAT RS20895
gene id: 189425:PGRAT_RS20895
uniprot id: A0A089M9S8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

189425:PGRAT RS17345
gene id: 189425:PGRAT_RS17345
uniprot id: A0A089MAF2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

189425:PGRAT RS12885
gene id: 189425:PGRAT_RS12885
uniprot id: A0A089M5M7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.

189425:PGRAT RS17600
gene id: 189425:PGRAT_RS17600
uniprot id: A0A089M6K6
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

189425:PGRAT RS30190
gene id: 189425:PGRAT_RS30190
uniprot id: A0A089MEA0
names: Similarity
messages: Belongs to the peptidase S8 family.

189425:PGRAT RS09545
gene id: 189425:PGRAT_RS09545
uniprot id: A0A089M6F6
names: Similarity
messages: Belongs to the glutamine synthetase family.

189425:PGRAT RS05925
gene id: 189425:PGRAT_RS05925
uniprot id: A0A089M703
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family.
messages: Cell membrane
messages: Membrane

189425:PGRAT RS27050
gene id: 189425:PGRAT_RS27050
uniprot id: A0A089MB68
names: Function
names: Subunit
messages: Counteracts the endogenous Pycsar antiviral defense system. Phosphodiesterase that enables metal-dependent hydrolysis of host cyclic nucleotide Pycsar defense signals such as cCMP and cUMP.
messages: Homodimer.

189425:PGRAT RS15925
gene id: 189425:PGRAT_RS15925
uniprot id: A0A089NJ38
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

189425:PGRAT RS20340
gene id: 189425:PGRAT_RS20340
uniprot id: A0A089M806
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

189425:PGRAT RS02050
gene id: 189425:PGRAT_RS02050
uniprot id: A0A089M085
names: Similarity
messages: Belongs to the CAPAB/TerDEXZ family.

189425:PGRAT RS02230
gene id: 189425:PGRAT_RS02230
uniprot id: A0A089M0B7
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

189425:PGRAT RS23445
gene id: 189425:PGRAT_RS23445
uniprot id: A0A089MB04
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

189425:PGRAT RS26000
gene id: 189425:PGRAT_RS26000
uniprot id: A0A089MHG7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

189425:PGRAT RS24885
gene id: 189425:PGRAT_RS24885
uniprot id: A0A089MGT6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

189425:PGRAT RS01370
gene id: 189425:PGRAT_RS01370
uniprot id: A0A089M4Q5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

189425:PGRAT RS23465
gene id: 189425:PGRAT_RS23465
uniprot id: A0A089M9I5
names: Similarity
messages: Belongs to the ABC transporter superfamily.

189425:PGRAT RS02885
gene id: 189425:PGRAT_RS02885
uniprot id: A0A089LYW8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase bacterial subunit 4 family.
messages: Membrane

189425:PGRAT RS29130
gene id: 189425:PGRAT_RS29130
uniprot id: A0A089MIY0
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

189425:PGRAT RS12555
gene id: 189425:PGRAT_RS12555
uniprot id: A0A089MAH8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the metallo-beta-lactamase superfamily. Class-B beta-lactamase family.
messages: Counteracts the endogenous Pycsar antiviral defense system. Phosphodiesterase that enables metal-dependent hydrolysis of host cyclic nucleotide Pycsar defense signals such as cCMP and cUMP.
messages: Homodimer.

189425:PGRAT RS12070
gene id: 189425:PGRAT_RS12070
uniprot id: A0A089M3M7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Cell membrane
messages: Membrane

189425:PGRAT RS22065
gene id: 189425:PGRAT_RS22065
uniprot id: A0A089M8T4
names: Similarity
messages: Belongs to the glycosyl hydrolase 10 (cellulase F) family.

189425:PGRAT RS02045
gene id: 189425:PGRAT_RS02045
uniprot id: A0A089LYG8
names: Similarity
messages: Belongs to the CAPAB/TerDEXZ family.

189425:PGRAT RS22510
gene id: 189425:PGRAT_RS22510
uniprot id: A0A089MAI2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

189425:PGRAT RS11410
gene id: 189425:PGRAT_RS11410
uniprot id: A0A089NGW3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

189425:PGRAT RS09530
gene id: 189425:PGRAT_RS09530
uniprot id: A0A089M418
names: Subcellular Location Annotation
messages: Membrane

189425:PGRAT RS13015
gene id: 189425:PGRAT_RS13015
uniprot id: A0A089M435
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MgtC/SapB family.
messages: Membrane

189425:PGRAT RS02030
gene id: 189425:PGRAT_RS02030
uniprot id: A0A089M4Z6
names: Subcellular Location Annotation
messages: Cell membrane

189425:PGRAT RS06820
gene id: 189425:PGRAT_RS06820
uniprot id: A0A089NEM4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobD/CbiB family.
messages: Cell membrane
messages: Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

189425:PGRAT RS12355
gene id: 189425:PGRAT_RS12355
uniprot id: A0A089M5F0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

189425:PGRAT RS06005
gene id: 189425:PGRAT_RS06005
uniprot id: A0A089M722
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NlpA lipoprotein family.
messages: Membrane

189425:PGRAT RS05650
gene id: 189425:PGRAT_RS05650
uniprot id: A0A089M4B2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

189425:PGRAT RS02430
gene id: 189425:PGRAT_RS02430
uniprot id: A0A089M2M0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the ABC transporter complex (TC 3.A.1.6.1) involved in sulfate/thiosulfate import.
messages: Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (CysA), two transmembrane proteins (CysT and CysW) and a solute-binding protein (CysP).

189425:PGRAT RS29675
gene id: 189425:PGRAT_RS29675
uniprot id: A0A089MCI5
names: Subcellular Location Annotation
messages: Cytoplasm

189425:PGRAT RS20475
gene id: 189425:PGRAT_RS20475
uniprot id: A0A089MC58
names: Similarity
messages: Belongs to the ABC transporter superfamily.

189425:PGRAT RS02585
gene id: 189425:PGRAT_RS02585
uniprot id: A0A089NCK8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

189425:PGRAT RS19625
gene id: 189425:PGRAT_RS19625
uniprot id: A0A089ME55
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

189425:PGRAT RS11380
gene id: 189425:PGRAT_RS11380
uniprot id: A0A089M9Q3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DEAD box helicase family. CshA subfamily.
messages: Cytoplasm
messages: DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA-dependent ATPase activity.
messages: Oligomerizes, may be a member of the RNA degradosome.

189425:PGRAT RS28730
gene id: 189425:PGRAT_RS28730
uniprot id: A0A089NQN2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

189425:PGRAT RS28045
gene id: 189425:PGRAT_RS28045
uniprot id: A0A089MBN9
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

189425:PGRAT RS00890
gene id: 189425:PGRAT_RS00890
uniprot id: A0A089LZN8
names: Similarity
messages: Belongs to the SorC transcriptional regulatory family.

189425:PGRAT RS18835
gene id: 189425:PGRAT_RS18835
uniprot id: A0A089MB72
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

189425:PGRAT RS04385
gene id: 189425:PGRAT_RS04385
uniprot id: A0A089M695
names: Similarity
messages: Belongs to the asparagine synthetase family.

189425:PGRAT RS30125
gene id: 189425:PGRAT_RS30125
uniprot id: A0A089NR91
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family.
messages: Cell membrane
messages: Membrane

189425:PGRAT RS15655
gene id: 189425:PGRAT_RS15655
uniprot id: A0A089M740
names: Cofactor
names: Function
names: PTM
names: Subcellular Location Annotation
messages: Autophosphorylated.
messages: Binds 1 [4Fe-4S] cluster.
messages: Cytoplasm
messages: Member of the two-component regulatory system NreB/NreC involved in the control of dissimilatory nitrate/nitrite reduction in response to oxygen. NreB functions as a direct oxygen sensor histidine kinase which is autophosphorylated, in the absence of oxygen, probably at the conserved histidine residue, and transfers its phosphate group probably to a conserved aspartate residue of NreC. NreB/NreC activates the expression of the nitrate (narGHJI) and nitrite (nir) reductase operons, as well as the putative nitrate transporter gene narT.

189425:PGRAT RS20450
gene id: 189425:PGRAT_RS20450
uniprot id: A0A089MC53
names: Function
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.
messages: In the phosphorylated form it could act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma f from inhibition.

189425:PGRAT RS19110
gene id: 189425:PGRAT_RS19110
uniprot id: A0A089M787
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

189425:PGRAT RS01760
gene id: 189425:PGRAT_RS01760
uniprot id: A0A089NC78
names: Similarity
messages: Belongs to the ABC transporter superfamily.

189425:PGRAT RS20705
gene id: 189425:PGRAT_RS20705
uniprot id: A0A089MC83
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

189425:PGRAT RS10355
gene id: 189425:PGRAT_RS10355
uniprot id: A0A089M4E6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I fumarase family.
messages: Catalyzes the reversible hydration of fumarate to (S)-malate.
messages: Homodimer.

189425:PGRAT RS21300
gene id: 189425:PGRAT_RS21300
uniprot id: A0A089NLY5
names: Similarity
messages: Belongs to the UxaA family.

189425:PGRAT RS21165
gene id: 189425:PGRAT_RS21165
uniprot id: A0A089MF00
names: Function
names: Similarity
messages: Belongs to the APS kinase family.
messages: Catalyzes the synthesis of activated sulfate.

189425:PGRAT RS20250
gene id: 189425:PGRAT_RS20250
uniprot id: A0A089NLH4
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

189425:PGRAT RS02620
gene id: 189425:PGRAT_RS02620
uniprot id: A0A089NCL2
names: Function
names: Similarity
messages: Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.
messages: Belongs to the organic radical-activating enzymes family.

189425:PGRAT RS16045
gene id: 189425:PGRAT_RS16045
uniprot id: A0A089M7A6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.
messages: Binds 1 S-adenosyl-L-methionine per subunit.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

189425:PGRAT RS18105
gene id: 189425:PGRAT_RS18105
uniprot id: A0A089NKC7
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.

189425:PGRAT RS22665
gene id: 189425:PGRAT_RS22665
uniprot id: A0A089MFQ1
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

189425:PGRAT RS17775
gene id: 189425:PGRAT_RS17775
uniprot id: A0A089MAR7
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliE family.

189425:PGRAT RS15510
gene id: 189425:PGRAT_RS15510
uniprot id: A0A089M5D3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

189425:PGRAT RS20165
gene id: 189425:PGRAT_RS20165
uniprot id: A0A089MEH8
names: Similarity
names: Subunit
messages: Belongs to the ENDOU family.
messages: Monomer.

189425:PGRAT RS17390
gene id: 189425:PGRAT_RS17390
uniprot id: A0A089NJX8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

189425:PGRAT RS13485
gene id: 189425:PGRAT_RS13485
uniprot id: A0A089M5X7
names: Similarity
messages: Belongs to the ABC transporter superfamily.

189425:PGRAT RS05935
gene id: 189425:PGRAT_RS05935
uniprot id: A0A089M4H3
names: Similarity
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Spore germination protein (SGP) (TC 2.A.3.9) family.

189425:PGRAT RS24890
gene id: 189425:PGRAT_RS24890
uniprot id: A0A089NNQ7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

189425:PGRAT RS28850
gene id: 189425:PGRAT_RS28850
uniprot id: A0A089MIU2
names: Subcellular Location Annotation
messages: Membrane

189425:PGRAT RS30555
gene id: 189425:PGRAT_RS30555
uniprot id: A0A089MH30
names: Function
names: Subunit
messages: Catalyzes the conversion of a range of fructosamine 6-phosphates to glucose 6-phosphate and a free amino acid.
messages: Homooctamer.

189425:PGRAT RS27035
gene id: 189425:PGRAT_RS27035
uniprot id: A0A089MHS2
names: Subcellular Location Annotation
messages: Membrane

189425:PGRAT RS11500
gene id: 189425:PGRAT_RS11500
uniprot id: A0A089M3B1
names: Caution
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

189425:PGRAT RS28765
gene id: 189425:PGRAT_RS28765
uniprot id: A0A089MC32
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

189425:PGRAT RS24185
gene id: 189425:PGRAT_RS24185
uniprot id: A0A089MGF2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

189425:PGRAT RS26010
gene id: 189425:PGRAT_RS26010
uniprot id: A0A089MEY4
names: Similarity
messages: Belongs to the GbsR family.

189425:PGRAT RS12865
gene id: 189425:PGRAT_RS12865
uniprot id: A0A089MAM5
names: Similarity
messages: Belongs to the RemA family.

189425:PGRAT RS24140
gene id: 189425:PGRAT_RS24140
uniprot id: A0A089NNA8
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.

189425:PGRAT RS07110
gene id: 189425:PGRAT_RS07110
uniprot id: A0A089M177
names: Subcellular Location Annotation
messages: Membrane

189425:PGRAT RS07150
gene id: 189425:PGRAT_RS07150
uniprot id: A0A089NES1
names: Subcellular Location Annotation
messages: cell wall

189425:PGRAT RS03920
gene id: 189425:PGRAT_RS03920
uniprot id: A0A089M3I8
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

189425:PGRAT RS15545
gene id: 189425:PGRAT_RS15545
uniprot id: A0A089M724
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

189425:PGRAT RS07115
gene id: 189425:PGRAT_RS07115
uniprot id: A0A089M2T7
names: Subcellular Location Annotation
messages: Membrane

189425:PGRAT RS00630
gene id: 189425:PGRAT_RS00630
uniprot id: A0A089M1Q5
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

189425:PGRAT RS22085
gene id: 189425:PGRAT_RS22085
uniprot id: A0A089MCX3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

189425:PGRAT RS15540
gene id: 189425:PGRAT_RS15540
uniprot id: A0A089M5D9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

189425:PGRAT RS27955
gene id: 189425:PGRAT_RS27955
uniprot id: A0A089NQ65
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

189425:PGRAT RS00225
gene id: 189425:PGRAT_RS00225
uniprot id: A0A089M1H2
names: Subcellular Location Annotation
messages: Membrane

189425:PGRAT RS17280
gene id: 189425:PGRAT_RS17280
uniprot id: A0A089M7W8
names: Similarity
messages: Belongs to the glycosyl hydrolase 42 family.

189425:PGRAT RS27540
gene id: 189425:PGRAT_RS27540
uniprot id: A0A089MFK4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PEPCase type 1 family.
messages: Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.
messages: Homotetramer.

189425:PGRAT RS08945
gene id: 189425:PGRAT_RS08945
uniprot id: A0A089M626
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

189425:PGRAT RS02005
gene id: 189425:PGRAT_RS02005
uniprot id: A0A089M4Z2
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

189425:PGRAT RS02325
gene id: 189425:PGRAT_RS02325
uniprot id: A0A089LYM1
names: Similarity
messages: Belongs to the UPF0045 family.

189425:PGRAT RS28380
gene id: 189425:PGRAT_RS28380
uniprot id: A0A089MIH4
names: Subcellular Location Annotation
messages: Membrane

189425:PGRAT RS02755
gene id: 189425:PGRAT_RS02755
uniprot id: A0A089M0J5
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

189425:PGRAT RS01080
gene id: 189425:PGRAT_RS01080
uniprot id: A0A089LZV0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

189425:PGRAT RS05950
gene id: 189425:PGRAT_RS05950
uniprot id: A0A089M710
names: Similarity
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Spore germination protein (SGP) (TC 2.A.3.9) family.

189425:PGRAT RS29815
gene id: 189425:PGRAT_RS29815
uniprot id: A0A089MCK9
names: Subcellular Location Annotation
messages: Membrane

189425:PGRAT RS04910
gene id: 189425:PGRAT_RS04910
uniprot id: A0A089M1N1
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

189425:PGRAT RS23550
gene id: 189425:PGRAT_RS23550
uniprot id: A0A089MG68
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

189425:PGRAT RS27475
gene id: 189425:PGRAT_RS27475
uniprot id: A0A089NPX2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

189425:PGRAT RS21195
gene id: 189425:PGRAT_RS21195
uniprot id: A0A089NLW9
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

189425:PGRAT RS10415
gene id: 189425:PGRAT_RS10415
uniprot id: A0A089NGD9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

189425:PGRAT RS12590
gene id: 189425:PGRAT_RS12590
uniprot id: A0A089M7Z4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 6-phosphogluconate dehydrogenase family.
messages: Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
messages: Homodimer.

189425:PGRAT RS06860
gene id: 189425:PGRAT_RS06860
uniprot id: A0A089M523
names: Function
names: Similarity
messages: Belongs to the CobB/CobQ family. CobQ subfamily.
messages: Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation.

189425:PGRAT RS11250
gene id: 189425:PGRAT_RS11250
uniprot id: A0A089M4S6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protoporphyrinogen/coproporphyrinogen oxidase family. Coproporphyrinogen III oxidase subfamily.
messages: Cytoplasm
messages: Involved in coproporphyrin-dependent heme b biosynthesis. Catalyzes the oxidation of coproporphyrinogen III to coproporphyrin III.

189425:PGRAT RS23645
gene id: 189425:PGRAT_RS23645
uniprot id: A0A089MB35
names: Similarity
messages: Belongs to the UPF0178 family.

189425:PGRAT RS08830
gene id: 189425:PGRAT_RS08830
uniprot id: A0A089M8G2
names: Similarity
messages: Belongs to the glycosyl hydrolase 5 (cellulase A) family.

189425:PGRAT RS05340
gene id: 189425:PGRAT_RS05340
uniprot id: A0A089M446
names: Subcellular Location Annotation
messages: Membrane

189425:PGRAT RS00600
gene id: 189425:PGRAT_RS00600
uniprot id: A0A089NBP6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

189425:PGRAT RS17805
gene id: 189425:PGRAT_RS17805
uniprot id: A0A089M6N3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

189425:PGRAT RS03675
gene id: 189425:PGRAT_RS03675
uniprot id: A0A089LZC7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the serine/threonine dehydratase family.
messages: Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.
messages: Homotetramer.

189425:PGRAT RS04510
gene id: 189425:PGRAT_RS04510
uniprot id: A0A089M6A9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

189425:PGRAT RS20175
gene id: 189425:PGRAT_RS20175
uniprot id: A0A089MBZ2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ScpB family.
messages: Cytoplasm
messages: Homodimer. Homodimerization may be required to stabilize the binding of ScpA to the Smc head domains. Component of a cohesin-like complex composed of ScpA, ScpB and the Smc homodimer, in which ScpA and ScpB bind to the head domain of Smc. The presence of the three proteins is required for the association of the complex with DNA.
messages: Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves.

189425:PGRAT RS07995
gene id: 189425:PGRAT_RS07995
uniprot id: A0A089M370
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

189425:PGRAT RS27145
gene id: 189425:PGRAT_RS27145
uniprot id: A0A089NPR4
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

189425:PGRAT RS00280
gene id: 189425:PGRAT_RS00280
uniprot id: A0A089LXK6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Cytoplasm
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
messages: The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.

189425:PGRAT RS12595
gene id: 189425:PGRAT_RS12595
uniprot id: A0A089M3W3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

189425:PGRAT RS01770
gene id: 189425:PGRAT_RS01770
uniprot id: A0A089LYC7
names: Function
names: Subunit
messages: Counteracts the endogenous Pycsar antiviral defense system. Phosphodiesterase that enables metal-dependent hydrolysis of host cyclic nucleotide Pycsar defense signals such as cCMP and cUMP.
messages: Homodimer.

189425:PGRAT RS11900
gene id: 189425:PGRAT_RS11900
uniprot id: A0A089MA14
names: Similarity
messages: Belongs to the ThiD family.

189425:PGRAT RS09220
gene id: 189425:PGRAT_RS09220
uniprot id: A0A089M8P0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0719 family.
messages: Membrane

189425:PGRAT RS16980
gene id: 189425:PGRAT_RS16980
uniprot id: A0A089MA85
names: Subcellular Location Annotation
messages: Membrane

189425:PGRAT RS21105
gene id: 189425:PGRAT_RS21105
uniprot id: A0A089M8B9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family.
messages: Cell membrane
messages: Membrane

189425:PGRAT RS16325
gene id: 189425:PGRAT_RS16325
uniprot id: A0A089M9W6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate.
messages: Cytoplasm

189425:PGRAT RS12440
gene id: 189425:PGRAT_RS12440
uniprot id: A0A089NHD1
names: Similarity
messages: Belongs to the DNA polymerase type-Y family.

189425:PGRAT RS20555
gene id: 189425:PGRAT_RS20555
uniprot id: A0A089M830
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phosphopentomutase family.
messages: Binds 1 or 2 manganese ions.
messages: Cytoplasm
messages: Phosphotransfer between the C1 and C5 carbon atoms of pentose.

189425:PGRAT RS08465
gene id: 189425:PGRAT_RS08465
uniprot id: A0A089M871
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The enzyme II CmtAB PTS system is involved in D-mannitol transport.

189425:PGRAT RS03225
gene id: 189425:PGRAT_RS03225
uniprot id: A0A089LZ40
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.
messages: Homodimer.

189425:PGRAT RS24210
gene id: 189425:PGRAT_RS24210
uniprot id: A0A089MGF7
names: Subcellular Location Annotation
messages: Membrane

189425:PGRAT RS17590
gene id: 189425:PGRAT_RS17590
uniprot id: A0A089NK47
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by GTP. Inhibited by UTP.
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

189425:PGRAT RS28520
gene id: 189425:PGRAT_RS28520
uniprot id: A0A089NQI8
names: Subcellular Location Annotation
messages: Cytoplasm

189425:PGRAT RS00995
gene id: 189425:PGRAT_RS00995
uniprot id: A0A089LY23
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.
messages: Belongs to the organic radical-activating enzymes family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm

189425:PGRAT RS19305
gene id: 189425:PGRAT_RS19305
uniprot id: A0A089MDY8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

189425:PGRAT RS23290
gene id: 189425:PGRAT_RS23290
uniprot id: A0A089M9F9
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

189425:PGRAT RS00840
gene id: 189425:PGRAT_RS00840
uniprot id: A0A089M4E3
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

189425:PGRAT RS03255
gene id: 189425:PGRAT_RS03255
uniprot id: A0A089M0T9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Cell membrane
messages: Membrane

189425:PGRAT RS23670
gene id: 189425:PGRAT_RS23670
uniprot id: A0A089MB39
names: Function
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.

189425:PGRAT RS22145
gene id: 189425:PGRAT_RS22145
uniprot id: A0A089M8U7
names: Similarity
messages: Belongs to the glycosyl hydrolase 8 (cellulase D) family.

189425:PGRAT RS00235
gene id: 189425:PGRAT_RS00235
uniprot id: A0A089LZA8
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

189425:PGRAT RS17300
gene id: 189425:PGRAT_RS17300
uniprot id: A0A089M6B3
names: Subcellular Location Annotation
messages: Membrane

189425:PGRAT RS09855
gene id: 189425:PGRAT_RS09855
uniprot id: A0A089M468
names: Subcellular Location Annotation
messages: Membrane

189425:PGRAT RS04520
gene id: 189425:PGRAT_RS04520
uniprot id: A0A089M3R7
names: Similarity
messages: Belongs to the glycosyl hydrolase 38 family.

189425:PGRAT RS09160
gene id: 189425:PGRAT_RS09160
uniprot id: A0A089M673
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The phosphoryl group from phosphoenolpyruvate (PEP) is transferred to the phosphoryl carrier protein HPr by enzyme I. Phospho-HPr then transfers it to the PTS EIIA domain.

189425:PGRAT RS06265
gene id: 189425:PGRAT_RS06265
uniprot id: A0A089M0Q4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

189425:PGRAT RS07305
gene id: 189425:PGRAT_RS07305
uniprot id: A0A089M2X0
names: Subcellular Location Annotation
messages: Membrane

189425:PGRAT RS05730
gene id: 189425:PGRAT_RS05730
uniprot id: A0A089M0E0
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.

189425:PGRAT RS03485
gene id: 189425:PGRAT_RS03485
uniprot id: A0A089NCZ9
names: Function
messages: Involved in some intermediate steps for the synthesis of the antibiotic polyketide bacillaene which is involved in secondary metabolism.

189425:PGRAT RS01415
gene id: 189425:PGRAT_RS01415
uniprot id: A0A089M001
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

189425:PGRAT RS10830
gene id: 189425:PGRAT_RS10830
uniprot id: A0A089M310
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

189425:PGRAT RS13705
gene id: 189425:PGRAT_RS13705
uniprot id: A0A089M605
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

189425:PGRAT RS19945
gene id: 189425:PGRAT_RS19945
uniprot id: A0A089MBT6
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

189425:PGRAT RS21655
gene id: 189425:PGRAT_RS21655
uniprot id: A0A089MF84
names: Similarity
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Spore germination protein (SGP) (TC 2.A.3.9) family.

189425:PGRAT RS03290
gene id: 189425:PGRAT_RS03290
uniprot id: A0A089M0U3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

189425:PGRAT RS02250
gene id: 189425:PGRAT_RS02250
uniprot id: A0A089LYK7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. EmrB family.
messages: Cell membrane
messages: Membrane

189425:PGRAT RS16585
gene id: 189425:PGRAT_RS16585
uniprot id: A0A089MA21
names: Similarity
messages: Belongs to the AP endonuclease 2 family.

189425:PGRAT RS09250
gene id: 189425:PGRAT_RS09250
uniprot id: A0A089M8P6
names: Similarity
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.

189425:PGRAT RS30910
gene id: 189425:PGRAT_RS30910
uniprot id: A0A089MH94
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

189425:PGRAT RS15170
gene id: 189425:PGRAT_RS15170
uniprot id: A0A089M9C8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily.
messages: Binds 2 Zn(2+) ions per subunit. It is not clear if Zn(2+) or Mg(2+) is physiologically important.
messages: Counteracts the endogenous Pycsar antiviral defense system. Phosphodiesterase that enables metal-dependent hydrolysis of host cyclic nucleotide Pycsar defense signals such as cCMP and cUMP.
messages: Cytoplasm
messages: Homodimer, may be a subunit of the RNA degradosome.

189425:PGRAT RS03265
gene id: 189425:PGRAT_RS03265
uniprot id: A0A089M5P5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0154 family.
messages: Membrane

189425:PGRAT RS16755
gene id: 189425:PGRAT_RS16755
uniprot id: A0A089NJJ7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

189425:PGRAT RS23250
gene id: 189425:PGRAT_RS23250
uniprot id: A0A089NMY8
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

189425:PGRAT RS09690
gene id: 189425:PGRAT_RS09690
uniprot id: A0A089M442
names: Similarity
messages: Belongs to the glycosyl hydrolase 65 family.

189425:PGRAT RS00040
gene id: 189425:PGRAT_RS00040
uniprot id: A0A089LXF4
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

189425:PGRAT RS13215
gene id: 189425:PGRAT_RS13215
uniprot id: A0A089M5T0
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

189425:PGRAT RS13590
gene id: 189425:PGRAT_RS13590
uniprot id: A0A089MAY1
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

189425:PGRAT RS12165
gene id: 189425:PGRAT_RS12165
uniprot id: A0A089M3Q6
names: Similarity
messages: Belongs to the DinB family.

189425:PGRAT RS09735
gene id: 189425:PGRAT_RS09735
uniprot id: A0A089M6H6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

189425:PGRAT RS02055
gene id: 189425:PGRAT_RS02055
uniprot id: A0A089M4Z9
names: Similarity
messages: Belongs to the CAPAB/TerDEXZ family.

189425:PGRAT RS19665
gene id: 189425:PGRAT_RS19665
uniprot id: A0A089M7I5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Mg(2+). Can also accept Mn(2+).

189425:PGRAT RS00085
gene id: 189425:PGRAT_RS00085
uniprot id: A0A089LZ75
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

189425:PGRAT RS26580
gene id: 189425:PGRAT_RS26580
uniprot id: A0A089NPK0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

189425:PGRAT RS04810
gene id: 189425:PGRAT_RS04810
uniprot id: A0A089NDK2
names: Subcellular Location Annotation
messages: Membrane

189425:PGRAT RS10740
gene id: 189425:PGRAT_RS10740
uniprot id: A0A089M6X9
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

189425:PGRAT RS11680
gene id: 189425:PGRAT_RS11680
uniprot id: A0A089M7F4
names: Subcellular Location Annotation
messages: Membrane

189425:PGRAT RS07035
gene id: 189425:PGRAT_RS07035
uniprot id: A0A089M162
names: Cofactor
names: Similarity
messages: Belongs to the mannose-6-phosphate isomerase type 1 family.
messages: Binds 1 zinc ion per subunit.

189425:PGRAT RS18985
gene id: 189425:PGRAT_RS18985
uniprot id: A0A089MDS6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. EmrB family.
messages: Cell membrane
messages: Membrane

189425:PGRAT RS06690
gene id: 189425:PGRAT_RS06690
uniprot id: A0A089M116
names: Similarity
messages: Belongs to the UPF0047 family.

189425:PGRAT RS27210
gene id: 189425:PGRAT_RS27210
uniprot id: A0A089MB98
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
messages: Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
messages: Cytoplasm

189425:PGRAT RS29000
gene id: 189425:PGRAT_RS29000
uniprot id: A0A089MGD8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

189425:PGRAT RS23805
gene id: 189425:PGRAT_RS23805
uniprot id: A0A089NN69
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Cell membrane
messages: Membrane

189425:PGRAT RS03710
gene id: 189425:PGRAT_RS03710
uniprot id: A0A089M5Y7
names: Similarity
messages: Belongs to the UPF0111 family.

189425:PGRAT RS20840
gene id: 189425:PGRAT_RS20840
uniprot id: A0A089M870
names: Function
names: Similarity
messages: Belongs to the aspartokinase family.
messages: Catalyzes the phosphorylation of the beta-carboxyl group of aspartic acid with ATP to yield 4-phospho-L-aspartate, which is involved in the branched biosynthetic pathway leading to the biosynthesis of amino acids threonine, isoleucine and methionine.

189425:PGRAT RS25585
gene id: 189425:PGRAT_RS25585
uniprot id: A0A089MEN9
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

189425:PGRAT RS02765
gene id: 189425:PGRAT_RS02765
uniprot id: A0A089NCN4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NADH dehydrogenase family.
messages: Membrane

189425:PGRAT RS27175
gene id: 189425:PGRAT_RS27175
uniprot id: A0A089MFE4
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

189425:PGRAT RS22005
gene id: 189425:PGRAT_RS22005
uniprot id: A0A089MAA4
names: Similarity
messages: Belongs to the glycosyl hydrolase 27 family.
messages: Belongs to the glycosyl hydrolase 36 family.

189425:PGRAT RS06260
gene id: 189425:PGRAT_RS06260
uniprot id: A0A089M4N9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

189425:PGRAT RS15680
gene id: 189425:PGRAT_RS15680
uniprot id: A0A089M746
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
messages: Cell membrane
messages: Membrane

189425:PGRAT RS12335
gene id: 189425:PGRAT_RS12335
uniprot id: A0A089MAE6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

189425:PGRAT RS08980
gene id: 189425:PGRAT_RS08980
uniprot id: A0A089M235
names: Subcellular Location Annotation
messages: Membrane

189425:PGRAT RS10530
gene id: 189425:PGRAT_RS10530
uniprot id: A0A089M9A9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

189425:PGRAT RS17935
gene id: 189425:PGRAT_RS17935
uniprot id: A0A089MAT5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A probable RNA chaperone. Forms a complex with KhpB which binds to cellular RNA and controls its expression. Plays a role in peptidoglycan (PG) homeostasis and cell length regulation.
messages: Belongs to the KhpA RNA-binding protein family.
messages: Cytoplasm
messages: Forms a complex with KhpB.

189425:PGRAT RS10265
gene id: 189425:PGRAT_RS10265
uniprot id: A0A089M6P3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccA family.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

189425:PGRAT RS25770
gene id: 189425:PGRAT_RS25770
uniprot id: A0A089NP85
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nlpA lipoprotein family.
messages: Membrane

189425:PGRAT RS15155
gene id: 189425:PGRAT_RS15155
uniprot id: A0A089M6W7
names: Similarity
messages: Belongs to the glycosyl hydrolase 5 (cellulase A) family.

189425:PGRAT RS16990
gene id: 189425:PGRAT_RS16990
uniprot id: A0A089M7R5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

189425:PGRAT RS04045
gene id: 189425:PGRAT_RS04045
uniprot id: A0A089M1A3
names: Similarity
messages: Belongs to the UPF0145 family.

189425:PGRAT RS01545
gene id: 189425:PGRAT_RS01545
uniprot id: A0A089LY99
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

189425:PGRAT RS28810
gene id: 189425:PGRAT_RS28810
uniprot id: A0A089MGB7
names: Similarity
messages: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.

189425:PGRAT RS00495
gene id: 189425:PGRAT_RS00495
uniprot id: A0A089NBM7
names: PTM
messages: Binds 1 heme c group covalently per subunit.

189425:PGRAT RS09730
gene id: 189425:PGRAT_RS09730
uniprot id: A0A089NG24
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. MalFG subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the ABC transporter complex MalEFGK involved in maltose/maltodextrin import. Probably responsible for the translocation of the substrate across the membrane.

189425:PGRAT RS10205
gene id: 189425:PGRAT_RS10205
uniprot id: A0A089M967
names: Similarity
messages: Belongs to the UPF0342 family.

189425:PGRAT RS11450
gene id: 189425:PGRAT_RS11450
uniprot id: A0A089M3A3
names: Similarity
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family.

189425:PGRAT RS17820
gene id: 189425:PGRAT_RS17820
uniprot id: A0A089NK84
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

189425:PGRAT RS17665
gene id: 189425:PGRAT_RS17665
uniprot id: A0A089NK59
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTP-binding SRP family.
messages: Cell membrane
messages: Membrane
messages: Necessary for flagellar biosynthesis. May be involved in translocation of the flagellum.

189425:PGRAT RS05875
gene id: 189425:PGRAT_RS05875
uniprot id: A0A089M6Z1
names: Similarity
messages: Belongs to the EamA transporter family.

189425:PGRAT RS07610
gene id: 189425:PGRAT_RS07610
uniprot id: A0A089NEZ8
names: Subcellular Location Annotation
messages: Membrane

189425:PGRAT RS06850
gene id: 189425:PGRAT_RS06850
uniprot id: A0A089M7J7
names: Function
names: Similarity
messages: Belongs to the CobU/CobP family.
messages: Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate.

189425:PGRAT RS26505
gene id: 189425:PGRAT_RS26505
uniprot id: A0A089MF41
names: Subcellular Location Annotation
messages: Membrane

189425:PGRAT RS04350
gene id: 189425:PGRAT_RS04350
uniprot id: A0A089LZQ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 5 family.
messages: Cell membrane
messages: Membrane

189425:PGRAT RS04965
gene id: 189425:PGRAT_RS04965
uniprot id: A0A089M000
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

189425:PGRAT RS27795
gene id: 189425:PGRAT_RS27795
uniprot id: A0A089MD16
names: Similarity
messages: Belongs to the sulfate adenylyltransferase family.

189425:PGRAT RS28720
gene id: 189425:PGRAT_RS28720
uniprot id: A0A089MDJ1
names: Similarity
messages: Belongs to the flagella basal body rod proteins family.

189425:PGRAT RS01565
gene id: 189425:PGRAT_RS01565
uniprot id: A0A089M4S9
names: Similarity
messages: Belongs to the glycosyl hydrolase 3 family.

189425:PGRAT RS00720
gene id: 189425:PGRAT_RS00720
uniprot id: A0A089NBQ7
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HPrK/P family.
messages: Both phosphorylation and phosphorolysis are carried out by the same active site and suggest a common mechanism for both reactions.
messages: Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr). The two antagonistic activities of HprK/P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK/P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport: it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion.
messages: Homohexamer.
messages: The Walker A ATP-binding motif also binds Pi and PPi.

189425:PGRAT RS17100
gene id: 189425:PGRAT_RS17100
uniprot id: A0A089MCU2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. MoaA family.
messages: Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.
messages: Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
messages: Monomer and homodimer.

189425:PGRAT RS22595
gene id: 189425:PGRAT_RS22595
uniprot id: A0A089MAK0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

189425:PGRAT RS29140
gene id: 189425:PGRAT_RS29140
uniprot id: A0A089MGF3
names: Subcellular Location Annotation
messages: Membrane

189425:PGRAT RS16485
gene id: 189425:PGRAT_RS16485
uniprot id: A0A089M5W0
names: Function
names: Similarity
messages: Belongs to the dihydrofolate reductase family.
messages: Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.

189425:PGRAT RS00395
gene id: 189425:PGRAT_RS00395
uniprot id: A0A089M1K7
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

189425:PGRAT RS19650
gene id: 189425:PGRAT_RS19650
uniprot id: A0A089ME65
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

189425:PGRAT RS04820
gene id: 189425:PGRAT_RS04820
uniprot id: A0A089LZX4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

189425:PGRAT RS05450
gene id: 189425:PGRAT_RS05450
uniprot id: A0A089M080
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

189425:PGRAT RS06940
gene id: 189425:PGRAT_RS06940
uniprot id: A0A089M532
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ApbE family.
messages: Cell inner membrane
messages: Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein.
messages: Magnesium. Can also use manganese.

189425:PGRAT RS20215
gene id: 189425:PGRAT_RS20215
uniprot id: A0A089MEJ0
names: Subcellular Location Annotation
messages: Cell membrane

189425:PGRAT RS09985
gene id: 189425:PGRAT_RS09985
uniprot id: A0A089M490
names: Subcellular Location Annotation
messages: Membrane

189425:PGRAT RS26815
gene id: 189425:PGRAT_RS26815
uniprot id: A0A089MF80
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

189425:PGRAT RS03325
gene id: 189425:PGRAT_RS03325
uniprot id: A0A089M5Q9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family.
messages: Catalyzes the isomerization of citrate to isocitrate via cis-aconitate.
messages: Monomer.

189425:PGRAT RS16455
gene id: 189425:PGRAT_RS16455
uniprot id: A0A089M5V5
names: Similarity
messages: Belongs to the GerABKC lipoprotein family.

189425:PGRAT RS14480
gene id: 189425:PGRAT_RS14480
uniprot id: A0A089M4V2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

189425:PGRAT RS14495
gene id: 189425:PGRAT_RS14495
uniprot id: A0A089NIE7
names: Subcellular Location Annotation
messages: Membrane

189425:PGRAT RS11550
gene id: 189425:PGRAT_RS11550
uniprot id: A0A089M4W9
names: Similarity
messages: Belongs to the thioredoxin family.

189425:PGRAT RS17785
gene id: 189425:PGRAT_RS17785
uniprot id: A0A089M874
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of a number of rings mounted on a central rod.

189425:PGRAT RS15395
gene id: 189425:PGRAT_RS15395
uniprot id: A0A089NIW6
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

189425:PGRAT RS28205
gene id: 189425:PGRAT_RS28205
uniprot id: A0A089NQC1
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.

189425:PGRAT RS11255
gene id: 189425:PGRAT_RS11255
uniprot id: A0A089M9M6
names: Similarity
messages: Belongs to the CapA family.

189425:PGRAT RS03160
gene id: 189425:PGRAT_RS03160
uniprot id: A0A089M5M0
names: Function
names: Similarity
messages: Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis.
messages: Belongs to the glycogen phosphorylase family.
messages: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.

189425:PGRAT RS00480
gene id: 189425:PGRAT_RS00480
uniprot id: A0A089LXP6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MotA family.
messages: Membrane

189425:PGRAT RS28795
gene id: 189425:PGRAT_RS28795
uniprot id: A0A089MDM7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase A chain family.
messages: Cell membrane
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

189425:PGRAT RS13370
gene id: 189425:PGRAT_RS13370
uniprot id: A0A089M5V8
names: Similarity
messages: Belongs to the ThiD family.

189425:PGRAT RS26835
gene id: 189425:PGRAT_RS26835
uniprot id: A0A089NPM3
names: Subcellular Location Annotation
messages: Membrane

189425:PGRAT RS03600
gene id: 189425:PGRAT_RS03600
uniprot id: A0A089M102
names: Similarity
messages: Belongs to the SAICAR synthetase family.

189425:PGRAT RS06410
gene id: 189425:PGRAT_RS06410
uniprot id: A0A089M7B4
names: Subcellular Location Annotation
messages: Membrane

189425:PGRAT RS03950
gene id: 189425:PGRAT_RS03950
uniprot id: A0A089LZJ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

189425:PGRAT RS00120
gene id: 189425:PGRAT_RS00120
uniprot id: A0A089NBG7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

189425:PGRAT RS27355
gene id: 189425:PGRAT_RS27355
uniprot id: A0A089MHX7
names: Similarity
messages: Belongs to the bacterial solute-binding protein 1 family.

189425:PGRAT RS02800
gene id: 189425:PGRAT_RS02800
uniprot id: A0A089LYV1
names: Similarity
messages: Belongs to the RutC family.

189425:PGRAT RS16295
gene id: 189425:PGRAT_RS16295
uniprot id: A0A089NJA0
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

189425:PGRAT RS01930
gene id: 189425:PGRAT_RS01930
uniprot id: A0A089M2C7
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

189425:PGRAT RS30850
gene id: 189425:PGRAT_RS30850
uniprot id: A0A089MJQ6
names: Subcellular Location Annotation
messages: Cytoplasm

189425:PGRAT RS23275
gene id: 189425:PGRAT_RS23275
uniprot id: A0A089MG23
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

189425:PGRAT RS09450
gene id: 189425:PGRAT_RS09450
uniprot id: A0A089M403
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family. LacC subfamily.
messages: Belongs to the carbohydrate kinase pfkB family.

189425:PGRAT RS02900
gene id: 189425:PGRAT_RS02900
uniprot id: A0A089NCQ4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

189425:PGRAT RS20915
gene id: 189425:PGRAT_RS20915
uniprot id: A0A089M885
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0161 family.
messages: Cell membrane
messages: Could be involved in insertion of integral membrane proteins into the membrane.

189425:PGRAT RS23310
gene id: 189425:PGRAT_RS23310
uniprot id: A0A089MDK3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

189425:PGRAT RS03720
gene id: 189425:PGRAT_RS03720
uniprot id: A0A089M3E8
names: Subcellular Location Annotation
messages: Cell membrane

189425:PGRAT RS05530
gene id: 189425:PGRAT_RS05530
uniprot id: A0A089M095
names: Subcellular Location Annotation
messages: Membrane

189425:PGRAT RS09240
gene id: 189425:PGRAT_RS09240
uniprot id: A0A089M3T7
names: Subcellular Location Annotation
messages: Cytoplasm

189425:PGRAT RS26940
gene id: 189425:PGRAT_RS26940
uniprot id: A0A089MB52
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

189425:PGRAT RS00725
gene id: 189425:PGRAT_RS00725
uniprot id: A0A089M1Q9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell membrane

189425:PGRAT RS30880
gene id: 189425:PGRAT_RS30880
uniprot id: A0A089NRP7
names: Subcellular Location Annotation
messages: Membrane

189425:PGRAT RS01250
gene id: 189425:PGRAT_RS01250
uniprot id: A0A089LZX5
names: Similarity
messages: Belongs to the glycosyl hydrolase 3 family.

189425:PGRAT RS23105
gene id: 189425:PGRAT_RS23105
uniprot id: A0A089MAW0
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.

189425:PGRAT RS23360
gene id: 189425:PGRAT_RS23360
uniprot id: A0A089MDL2
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

189425:PGRAT RS02715
gene id: 189425:PGRAT_RS02715
uniprot id: A0A089NCM4
names: Subcellular Location Annotation
messages: Membrane

189425:PGRAT RS20770
gene id: 189425:PGRAT_RS20770
uniprot id: A0A089MEU9
names: Similarity
messages: Belongs to the asp23 family.

189425:PGRAT RS11485
gene id: 189425:PGRAT_RS11485
uniprot id: A0A089M9S7
names: Caution
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

189425:PGRAT RS03625
gene id: 189425:PGRAT_RS03625
uniprot id: A0A089M110
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

189425:PGRAT RS26795
gene id: 189425:PGRAT_RS26795
uniprot id: A0A089MB34
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 zinc ion per subunit.

189425:PGRAT RS04310
gene id: 189425:PGRAT_RS04310
uniprot id: A0A089M684
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

189425:PGRAT RS09465
gene id: 189425:PGRAT_RS09465
uniprot id: A0A089M6E5
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

189425:PGRAT RS26450
gene id: 189425:PGRAT_RS26450
uniprot id: A0A089MAZ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

189425:PGRAT RS27345
gene id: 189425:PGRAT_RS27345
uniprot id: A0A089MBC3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

189425:PGRAT RS03470
gene id: 189425:PGRAT_RS03470
uniprot id: A0A089M0X8
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

189425:PGRAT RS16860
gene id: 189425:PGRAT_RS16860
uniprot id: A0A089NJM0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Also exhibits azoreductase activity. Catalyzes the reductive cleavage of the azo bond in aromatic azo compounds to the corresponding amines.
messages: Belongs to the azoreductase type 1 family.
messages: Binds 1 FMN per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Quinone reductase that provides resistance to thiol-specific stress caused by electrophilic quinones.

189425:PGRAT RS29350
gene id: 189425:PGRAT_RS29350
uniprot id: A0A089MCD4
names: Subcellular Location Annotation
messages: Membrane

189425:PGRAT RS27915
gene id: 189425:PGRAT_RS27915
uniprot id: A0A089MBL3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

189425:PGRAT RS08655
gene id: 189425:PGRAT_RS08655
uniprot id: A0A089M1X0
names: Function
messages: TetR is the repressor of the tetracycline resistance element; its N-terminal region forms a helix-turn-helix structure and binds DNA. Binding of tetracycline to TetR reduces the repressor affinity for the tetracycline resistance gene (tetA) promoter operator sites.

189425:PGRAT RS17800
gene id: 189425:PGRAT_RS17800
uniprot id: A0A089MAR9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmG family. TrmFO subfamily.
messages: Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs.
messages: Cytoplasm

189425:PGRAT RS00800
gene id: 189425:PGRAT_RS00800
uniprot id: A0A089M1S4
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the C-terminal section; belongs to the PRA-PH family.
messages: In the N-terminal section; belongs to the PRA-CH family.

189425:PGRAT RS29685
gene id: 189425:PGRAT_RS29685
uniprot id: A0A089MJ44
names: Function
names: Subunit
messages: Counteracts the endogenous Pycsar antiviral defense system. Phosphodiesterase that enables metal-dependent hydrolysis of host cyclic nucleotide Pycsar defense signals such as cCMP and cUMP.
messages: Homodimer.

189425:PGRAT RS19855
gene id: 189425:PGRAT_RS19855
uniprot id: A0A089M968
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

189425:PGRAT RS19125
gene id: 189425:PGRAT_RS19125
uniprot id: A0A089NKT5
names: Subcellular Location Annotation
messages: Membrane

189425:PGRAT RS28475
gene id: 189425:PGRAT_RS28475
uniprot id: A0A089MBX0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm

189425:PGRAT RS25940
gene id: 189425:PGRAT_RS25940
uniprot id: A0A089MAT3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

189425:PGRAT RS00585
gene id: 189425:PGRAT_RS00585
uniprot id: A0A089LXR5
names: Activity Regulation
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.

189425:PGRAT RS00350
gene id: 189425:PGRAT_RS00350
uniprot id: A0A089NBK5
names: Function
names: Similarity
messages: Belongs to the DHNA family.
messages: Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin.

189425:PGRAT RS11830
gene id: 189425:PGRAT_RS11830
uniprot id: A0A089M3H1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit E family.
messages: Cell membrane
messages: Membrane

189425:PGRAT RS23495
gene id: 189425:PGRAT_RS23495
uniprot id: A0A089MB13
names: Function
names: Similarity
messages: Belongs to the ketopantoate reductase family.
messages: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.

189425:PGRAT RS29835
gene id: 189425:PGRAT_RS29835
uniprot id: A0A089MGP9
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

189425:PGRAT RS28690
gene id: 189425:PGRAT_RS28690
uniprot id: A0A089MDI5
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 26 family. TagA/TarA subfamily.
messages: Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid.

189425:PGRAT RS12860
gene id: 189425:PGRAT_RS12860
uniprot id: A0A089M5M2
names: Similarity
messages: Belongs to the YicC/YloC family.

189425:PGRAT RS08740
gene id: 189425:PGRAT_RS08740
uniprot id: A0A089M3J7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

189425:PGRAT RS17510
gene id: 189425:PGRAT_RS17510
uniprot id: A0A089MD33
names: Similarity
messages: Belongs to the ribF family.

189425:PGRAT RS11425
gene id: 189425:PGRAT_RS11425
uniprot id: A0A089M4V3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

189425:PGRAT RS07435
gene id: 189425:PGRAT_RS07435
uniprot id: A0A089M2Y8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

189425:PGRAT RS17385
gene id: 189425:PGRAT_RS17385
uniprot id: A0A089MD03
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecX family.
messages: Cytoplasm
messages: Modulates RecA activity.

189425:PGRAT RS00820
gene id: 189425:PGRAT_RS00820
uniprot id: A0A089NBS8
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

189425:PGRAT RS17045
gene id: 189425:PGRAT_RS17045
uniprot id: A0A089MCS9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aldolase class II family. RhaD subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the reversible cleavage of L-rhamnulose-1-phosphate to dihydroxyacetone phosphate (DHAP) and L-lactaldehyde.
messages: Cytoplasm

189425:PGRAT RS17930
gene id: 189425:PGRAT_RS17930
uniprot id: A0A089NKA1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein uS19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein uS19.

189425:PGRAT RS06875
gene id: 189425:PGRAT_RS06875
uniprot id: A0A089M7J9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily.
messages: Cell membrane
messages: Involved in the import of queuosine (Q) precursors, required for Q precursor salvage.

189425:PGRAT RS23680
gene id: 189425:PGRAT_RS23680
uniprot id: A0A089NN49
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

189425:PGRAT RS03015
gene id: 189425:PGRAT_RS03015
uniprot id: A0A089NCS1
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.

189425:PGRAT RS23965
gene id: 189425:PGRAT_RS23965
uniprot id: A0A089M9R5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

189425:PGRAT RS30360
gene id: 189425:PGRAT_RS30360
uniprot id: A0A089MJE9
names: Caution
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HPrK/P family.
messages: Both phosphorylation and phosphorolysis are carried out by the same active site and suggest a common mechanism for both reactions.
messages: Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr). The two antagonistic activities of HprK/P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK/P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport: it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion.
messages: Homohexamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The Walker A ATP-binding motif also binds Pi and PPi.

189425:PGRAT RS24325
gene id: 189425:PGRAT_RS24325
uniprot id: A0A089NNE3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family.
messages: Cell membrane
messages: Membrane

189425:PGRAT RS13425
gene id: 189425:PGRAT_RS13425
uniprot id: A0A089M5W7
names: Subcellular Location Annotation
messages: Cell membrane

189425:PGRAT RS24070
gene id: 189425:PGRAT_RS24070
uniprot id: A0A089M9T7
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

189425:PGRAT RS01050
gene id: 189425:PGRAT_RS01050
uniprot id: A0A089LZU6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

189425:PGRAT RS00795
gene id: 189425:PGRAT_RS00795
uniprot id: A0A089NBS2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

189425:PGRAT RS12475
gene id: 189425:PGRAT_RS12475
uniprot id: A0A089M3V0
names: Similarity
messages: Belongs to the YciI family.

189425:PGRAT RS00580
gene id: 189425:PGRAT_RS00580
uniprot id: A0A089M1P4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RpoE family.
messages: Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling.
messages: RNAP is composed of a core of 2 alpha, a beta and a beta' subunits. The core is associated with a delta subunit and one of several sigma factors.

189425:PGRAT RS26370
gene id: 189425:PGRAT_RS26370
uniprot id: A0A089NPH4
names: Subcellular Location Annotation
messages: Membrane

189425:PGRAT RS17205
gene id: 189425:PGRAT_RS17205
uniprot id: A0A089MCW6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

189425:PGRAT RS25950
gene id: 189425:PGRAT_RS25950
uniprot id: A0A089MHG1
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

189425:PGRAT RS23740
gene id: 189425:PGRAT_RS23740
uniprot id: A0A089M9M8
names: Similarity
messages: Belongs to the TPP enzyme family.

189425:PGRAT RS18650
gene id: 189425:PGRAT_RS18650
uniprot id: A0A089MB41
names: Function
names: Similarity
messages: Belongs to the SELO family.
messages: Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr or Tyr residues of target proteins (AMPylation).

189425:PGRAT RS05330
gene id: 189425:PGRAT_RS05330
uniprot id: A0A089M6L4
names: Subcellular Location Annotation
messages: Membrane

189425:PGRAT RS16605
gene id: 189425:PGRAT_RS16605
uniprot id: A0A089NJG7
names: Domain
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 dependent methionine synthase family.
messages: Catalyzes the transfer of a methyl group from methyl-cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
messages: Modular enzyme with four functionally distinct domains. The isolated Hcy-binding domain catalyzes methyl transfer from free methylcobalamin to homocysteine. The Hcy-binding domain in association with the pterin-binding domain catalyzes the methylation of cob(I)alamin by methyltetrahydrofolate and the methylation of homocysteine. The B12-binding domain binds the cofactor. The AdoMet activation domain binds S-adenosyl-L-methionine. Under aerobic conditions cob(I)alamin can be converted to inactive cob(II)alamin. Reductive methylation by S-adenosyl-L-methionine and flavodoxin regenerates methylcobalamin.

189425:PGRAT RS08425
gene id: 189425:PGRAT_RS08425
uniprot id: A0A089M1S5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

189425:PGRAT RS04315
gene id: 189425:PGRAT_RS04315
uniprot id: A0A089NDD6
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.

189425:PGRAT RS01580
gene id: 189425:PGRAT_RS01580
uniprot id: A0A089LYA4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

189425:PGRAT RS00925
gene id: 189425:PGRAT_RS00925
uniprot id: A0A089NBU9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

189425:PGRAT RS28815
gene id: 189425:PGRAT_RS28815
uniprot id: A0A089MC65
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
messages: Allosterically activated by GTP.
messages: Belongs to the UPRTase family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.
messages: Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.

189425:PGRAT RS20455
gene id: 189425:PGRAT_RS20455
uniprot id: A0A089M820
names: Function
names: Similarity
messages: Belongs to the peptidase S11 family.
messages: Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors.

189425:PGRAT RS05200
gene id: 189425:PGRAT_RS05200
uniprot id: A0A089M6J1
names: Similarity
messages: Belongs to the antibiotic N-acetyltransferase family.

189425:PGRAT RS27940
gene id: 189425:PGRAT_RS27940
uniprot id: A0A089MBL8
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

189425:PGRAT RS27835
gene id: 189425:PGRAT_RS27835
uniprot id: A0A089MFP1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

189425:PGRAT RS05105
gene id: 189425:PGRAT_RS05105
uniprot id: A0A089M401
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Binds a copper B center.
messages: Catalyzes quinol oxidation with the concomitant reduction of oxygen to water.
messages: Cell membrane
messages: Heme A3.
messages: Membrane

189425:PGRAT RS30470
gene id: 189425:PGRAT_RS30470
uniprot id: A0A089MJH6
names: Subcellular Location Annotation
messages: Membrane

189425:PGRAT RS00410
gene id: 189425:PGRAT_RS00410
uniprot id: A0A089M460
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glutaminase PdxT/SNO family.
messages: Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS.
messages: In the presence of PdxS, forms a dodecamer of heterodimers. Only shows activity in the heterodimer.

189425:PGRAT RS10270
gene id: 189425:PGRAT_RS10270
uniprot id: A0A089M2R3
names: Similarity
messages: Belongs to the pyruvate kinase family.

189425:PGRAT RS09880
gene id: 189425:PGRAT_RS09880
uniprot id: A0A089M471
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane
messages: Membrane

189425:PGRAT RS17505
gene id: 189425:PGRAT_RS17505
uniprot id: A0A089M817
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

189425:PGRAT RS28105
gene id: 189425:PGRAT_RS28105
uniprot id: A0A089MIB6
names: Similarity
messages: Belongs to the ycf81 family.

189425:PGRAT RS15550
gene id: 189425:PGRAT_RS15550
uniprot id: A0A089MC13
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

189425:PGRAT RS05995
gene id: 189425:PGRAT_RS05995
uniprot id: A0A089M0J3
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

189425:PGRAT RS02810
gene id: 189425:PGRAT_RS02810
uniprot id: A0A089M5D4
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.

189425:PGRAT RS20725
gene id: 189425:PGRAT_RS20725
uniprot id: A0A089NLQ5
names: Similarity
messages: Belongs to the TlyA family.

189425:PGRAT RS17455
gene id: 189425:PGRAT_RS17455
uniprot id: A0A089M805
names: Similarity
messages: Belongs to the peptidase S14 family.

189425:PGRAT RS29285
gene id: 189425:PGRAT_RS29285
uniprot id: A0A089MGH0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TVP38/TMEM64 family.
messages: Cell membrane
messages: Membrane

189425:PGRAT RS27785
gene id: 189425:PGRAT_RS27785
uniprot id: A0A089MFN2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.
messages: In the C-terminal section; belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: In the N-terminal section; belongs to the MIP18 family.

189425:PGRAT RS18415
gene id: 189425:PGRAT_RS18415
uniprot id: A0A089MDI6
names: Similarity
messages: Belongs to the peptidase S14 family.

189425:PGRAT RS17515
gene id: 189425:PGRAT_RS17515
uniprot id: A0A089NK25
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

189425:PGRAT RS24515
gene id: 189425:PGRAT_RS24515
uniprot id: A0A089MA12
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

189425:PGRAT RS20780
gene id: 189425:PGRAT_RS20780
uniprot id: A0A089MC94
names: Function
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

189425:PGRAT RS06195
gene id: 189425:PGRAT_RS06195
uniprot id: A0A089M295
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

189425:PGRAT RS14310
gene id: 189425:PGRAT_RS14310
uniprot id: A0A089M4S7
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

189425:PGRAT RS29205
gene id: 189425:PGRAT_RS29205
uniprot id: A0A089MCB6
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

189425:PGRAT RS00340
gene id: 189425:PGRAT_RS00340
uniprot id: A0A089LZC9
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

189425:PGRAT RS28640
gene id: 189425:PGRAT_RS28640
uniprot id: A0A089MDH6
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Member of the two-component regulatory system DegS/DegU, which plays an important role in the transition growth phase.

189425:PGRAT RS27095
gene id: 189425:PGRAT_RS27095
uniprot id: A0A089MFC9
names: Subcellular Location Annotation
messages: Membrane

189425:PGRAT RS16505
gene id: 189425:PGRAT_RS16505
uniprot id: A0A089MA05
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

189425:PGRAT RS28750
gene id: 189425:PGRAT_RS28750
uniprot id: A0A089MIP9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

189425:PGRAT RS20560
gene id: 189425:PGRAT_RS20560
uniprot id: A0A089M9M3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerD subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

189425:PGRAT RS12580
gene id: 189425:PGRAT_RS12580
uniprot id: A0A089MAI6
names: Similarity
messages: Belongs to the UPF0637 family.

189425:PGRAT RS24280
gene id: 189425:PGRAT_RS24280
uniprot id: A0A089M9X6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.

189425:PGRAT RS15755
gene id: 189425:PGRAT_RS15755
uniprot id: A0A089M5H8
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

189425:PGRAT RS03620
gene id: 189425:PGRAT_RS03620
uniprot id: A0A089LZB3
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.

189425:PGRAT RS09790
gene id: 189425:PGRAT_RS09790
uniprot id: A0A089NG31
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0382 family.
messages: Membrane

189425:PGRAT RS18695
gene id: 189425:PGRAT_RS18695
uniprot id: A0A089NKJ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

189425:PGRAT RS09950
gene id: 189425:PGRAT_RS09950
uniprot id: A0A089M2M2
names: Similarity
messages: Belongs to the GerABKC lipoprotein family.

189425:PGRAT RS07425
gene id: 189425:PGRAT_RS07425
uniprot id: A0A089M595
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

189425:PGRAT RS12820
gene id: 189425:PGRAT_RS12820
uniprot id: A0A089M829
names: Function
names: Similarity
names: Subunit
messages: Associates with stalled 50S ribosomal subunits.
messages: Belongs to the NEMF family.
messages: Part of the ribosome quality control system (RQC). Recruits Ala-charged tRNA and directs the elongation of stalled nascent chains on 50S ribosomal subunits, leading to non-templated C-terminal Ala extensions (Ala tail). The Ala tail promotes nascent chain degradation. May add between 1 and at least 8 Ala residues. Binds to stalled 50S ribosomal subunits.

189425:PGRAT RS10835
gene id: 189425:PGRAT_RS10835
uniprot id: A0A089M4K8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

189425:PGRAT RS13620
gene id: 189425:PGRAT_RS13620
uniprot id: A0A089NHX2
names: Similarity
messages: Belongs to the glycosyl hydrolase 3 family.

189425:PGRAT RS04880
gene id: 189425:PGRAT_RS04880
uniprot id: A0A089LZY5
names: Subcellular Location Annotation
messages: Membrane

189425:PGRAT RS05225
gene id: 189425:PGRAT_RS05225
uniprot id: A0A089M6J4
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

189425:PGRAT RS01845
gene id: 189425:PGRAT_RS01845
uniprot id: A0A089M2B6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

189425:PGRAT RS11300
gene id: 189425:PGRAT_RS11300
uniprot id: A0A089M4T5
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

189425:PGRAT RS12320
gene id: 189425:PGRAT_RS12320
uniprot id: A0A089M7W3
names: Subcellular Location Annotation
messages: Membrane

189425:PGRAT RS28710
gene id: 189425:PGRAT_RS28710
uniprot id: A0A089MC22
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioester dehydratase family. FabZ subfamily.
messages: Cytoplasm
messages: Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.

189425:PGRAT RS16310
gene id: 189425:PGRAT_RS16310
uniprot id: A0A089M7E5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0719 family.
messages: Membrane

189425:PGRAT RS30090
gene id: 189425:PGRAT_RS30090
uniprot id: A0A089MJA0
names: Subcellular Location Annotation
messages: Membrane

189425:PGRAT RS17655
gene id: 189425:PGRAT_RS17655
uniprot id: A0A089M856
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CheB family.
messages: Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.
messages: Cytoplasm
messages: Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
messages: Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity.

189425:PGRAT RS16075
gene id: 189425:PGRAT_RS16075
uniprot id: A0A089MC86
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

189425:PGRAT RS05285
gene id: 189425:PGRAT_RS05285
uniprot id: A0A089NDT9
names: Similarity
messages: Belongs to the glycosyl hydrolase 20 family.

189425:PGRAT RS12920
gene id: 189425:PGRAT_RS12920
uniprot id: A0A089MAN2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

189425:PGRAT RS06830
gene id: 189425:PGRAT_RS06830
uniprot id: A0A089M519
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

189425:PGRAT RS13265
gene id: 189425:PGRAT_RS13265
uniprot id: A0A089M477
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

189425:PGRAT RS13490
gene id: 189425:PGRAT_RS13490
uniprot id: A0A089MAW4
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

189425:PGRAT RS10805
gene id: 189425:PGRAT_RS10805
uniprot id: A0A089M4K2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

189425:PGRAT RS14995
gene id: 189425:PGRAT_RS14995
uniprot id: A0A089M6U3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

189425:PGRAT RS19870
gene id: 189425:PGRAT_RS19870
uniprot id: A0A089MBS2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

189425:PGRAT RS09340
gene id: 189425:PGRAT_RS09340
uniprot id: A0A089M8S9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

189425:PGRAT RS06680
gene id: 189425:PGRAT_RS06680
uniprot id: A0A089NEK8
names: Similarity
messages: Belongs to the IMPACT family.

189425:PGRAT RS11605
gene id: 189425:PGRAT_RS11605
uniprot id: A0A089M4X5
names: Subcellular Location Annotation
messages: Membrane

189425:PGRAT RS23405
gene id: 189425:PGRAT_RS23405
uniprot id: A0A089NN08
names: Subcellular Location Annotation
messages: Membrane

189425:PGRAT RS02485
gene id: 189425:PGRAT_RS02485
uniprot id: A0A089LYQ1
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

189425:PGRAT RS20105
gene id: 189425:PGRAT_RS20105
uniprot id: A0A089M7S6
names: Subcellular Location Annotation
messages: Membrane

189425:PGRAT RS24720
gene id: 189425:PGRAT_RS24720
uniprot id: A0A089MBL1
names: Similarity
messages: Belongs to the acyltransferase 3 family.

189425:PGRAT RS24495
gene id: 189425:PGRAT_RS24495
uniprot id: A0A089MBH2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

189425:PGRAT RS02120
gene id: 189425:PGRAT_RS02120
uniprot id: A0A089LYI1
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

189425:PGRAT RS07060
gene id: 189425:PGRAT_RS07060
uniprot id: A0A089M168
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

189425:PGRAT RS03455
gene id: 189425:PGRAT_RS03455
uniprot id: A0A089M369
names: Similarity
messages: Belongs to the thioesterase family.

189425:PGRAT RS13985
gene id: 189425:PGRAT_RS13985
uniprot id: A0A089MB59
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

189425:PGRAT RS01455
gene id: 189425:PGRAT_RS01455
uniprot id: A0A089M265
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uridine kinase family.
messages: Cytoplasm

189425:PGRAT RS17400
gene id: 189425:PGRAT_RS17400
uniprot id: A0A089M6D4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane
messages: This protein catalyzes the committed step to the synthesis of the acidic phospholipids.

189425:PGRAT RS07415
gene id: 189425:PGRAT_RS07415
uniprot id: A0A089M7R9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

189425:PGRAT RS12705
gene id: 189425:PGRAT_RS12705
uniprot id: A0A089MAK3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

189425:PGRAT RS12075
gene id: 189425:PGRAT_RS12075
uniprot id: A0A089M572
names: Subunit
messages: Homodimer.

189425:PGRAT RS17795
gene id: 189425:PGRAT_RS17795
uniprot id: A0A089NK79
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: Allosterically activated by HslU binding.
messages: Belongs to the peptidase T1B family. HslV subfamily.
messages: Cytoplasm
messages: Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.

189425:PGRAT RS15585
gene id: 189425:PGRAT_RS15585
uniprot id: A0A089NIZ1
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

189425:PGRAT RS19630
gene id: 189425:PGRAT_RS19630
uniprot id: A0A089NL37
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

189425:PGRAT RS16005
gene id: 189425:PGRAT_RS16005
uniprot id: A0A089M9Q8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

189425:PGRAT RS06295
gene id: 189425:PGRAT_RS06295
uniprot id: A0A089M2B3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. TCR/Tet family.
messages: Cell membrane
messages: Membrane

189425:PGRAT RS30610
gene id: 189425:PGRAT_RS30610
uniprot id: A0A089MD05
names: Subcellular Location Annotation
messages: Membrane

189425:PGRAT RS21925
gene id: 189425:PGRAT_RS21925
uniprot id: A0A089MA92
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

189425:PGRAT RS05370
gene id: 189425:PGRAT_RS05370
uniprot id: A0A089M066
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

189425:PGRAT RS16760
gene id: 189425:PGRAT_RS16760
uniprot id: A0A089MA53
names: Similarity
messages: Belongs to the CbxX/CfxQ family.

189425:PGRAT RS00790
gene id: 189425:PGRAT_RS00790
uniprot id: A0A089M4D2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

189425:PGRAT RS23260
gene id: 189425:PGRAT_RS23260
uniprot id: A0A089M9F6
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

189425:PGRAT RS22495
gene id: 189425:PGRAT_RS22495
uniprot id: A0A089NML2
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

189425:PGRAT RS28215
gene id: 189425:PGRAT_RS28215
uniprot id: A0A089MBR5
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GGGP/HepGP synthase family. Group I subfamily.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Prenyltransferase that catalyzes in vivo the transfer of the heptaprenyl moiety of heptaprenyl pyrophosphate (HepPP; 35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales.

189425:PGRAT RS27640
gene id: 189425:PGRAT_RS27640
uniprot id: A0A089NQ10
names: Similarity
messages: Belongs to the myoviridae tail sheath protein family.

189425:PGRAT RS02490
gene id: 189425:PGRAT_RS02490
uniprot id: A0A089M0G1
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

189425:PGRAT RS12195
gene id: 189425:PGRAT_RS12195
uniprot id: A0A089M3R1
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

189425:PGRAT RS14475
gene id: 189425:PGRAT_RS14475
uniprot id: A0A089M8X5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

189425:PGRAT RS12000
gene id: 189425:PGRAT_RS12000
uniprot id: A0A089M555
names: Similarity
messages: Belongs to the Nudix hydrolase family.

189425:PGRAT RS17465
gene id: 189425:PGRAT_RS17465
uniprot id: A0A089NJZ1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

189425:PGRAT RS28130
gene id: 189425:PGRAT_RS28130
uniprot id: A0A089MIC2
names: Similarity
messages: Belongs to the ClpA/ClpB family.

189425:PGRAT RS16330
gene id: 189425:PGRAT_RS16330
uniprot id: A0A089M5T1
names: Cofactor
names: Similarity
messages: Belongs to the PyrK family.
messages: Binds 1 FAD per subunit.
messages: Binds 1 [2Fe-2S] cluster per subunit.

189425:PGRAT RS16090
gene id: 189425:PGRAT_RS16090
uniprot id: A0A089M5P2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

189425:PGRAT RS14540
gene id: 189425:PGRAT_RS14540
uniprot id: A0A089MBJ1
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

189425:PGRAT RS12350
gene id: 189425:PGRAT_RS12350
uniprot id: A0A089M3S9
names: Similarity
messages: Belongs to the ThrE exporter (TC 2.A.79) family.

189425:PGRAT RS10735
gene id: 189425:PGRAT_RS10735
uniprot id: A0A089NGJ5
names: Subcellular Location Annotation
messages: Membrane

189425:PGRAT RS13005
gene id: 189425:PGRAT_RS13005
uniprot id: A0A089NHK1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

189425:PGRAT RS11470
gene id: 189425:PGRAT_RS11470
uniprot id: A0A089M7C0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate with NAD(+) as electron acceptor.
messages: Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
messages: Cell membrane
messages: Heterotetramer of 2 PyrK and 2 PyrD type B subunits.
messages: Monomer.

189425:PGRAT RS17815
gene id: 189425:PGRAT_RS17815
uniprot id: A0A089MDB3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

189425:PGRAT RS01655
gene id: 189425:PGRAT_RS01655
uniprot id: A0A089LYB4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

189425:PGRAT RS24560
gene id: 189425:PGRAT_RS24560
uniprot id: A0A089ME53
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

189425:PGRAT RS27535
gene id: 189425:PGRAT_RS27535
uniprot id: A0A089NPY4
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

189425:PGRAT RS29800
gene id: 189425:PGRAT_RS29800
uniprot id: A0A089MJ56
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

189425:PGRAT RS07675
gene id: 189425:PGRAT_RS07675
uniprot id: A0A089M1H4
names: Similarity
messages: Belongs to the glycosyl hydrolase 27 family.

189425:PGRAT RS07385
gene id: 189425:PGRAT_RS07385
uniprot id: A0A089M2Y0
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.

189425:PGRAT RS27400
gene id: 189425:PGRAT_RS27400
uniprot id: A0A089MCV9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ArsB family.
messages: Cell membrane
messages: Involved in arsenical resistance. Thought to form the channel of an arsenite pump.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

189425:PGRAT RS28125
gene id: 189425:PGRAT_RS28125
uniprot id: A0A089MD82
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

189425:PGRAT RS11405
gene id: 189425:PGRAT_RS11405
uniprot id: A0A089M9R0
names: Subcellular Location Annotation
messages: Membrane

189425:PGRAT RS27100
gene id: 189425:PGRAT_RS27100
uniprot id: A0A089MB78
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Catalyzes the phosphorylation of D-xylulose to D-xylulose 5-phosphate.

189425:PGRAT RS23610
gene id: 189425:PGRAT_RS23610
uniprot id: A0A089MDQ0
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

189425:PGRAT RS20745
gene id: 189425:PGRAT_RS20745
uniprot id: A0A089MEU6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseA family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

189425:PGRAT RS25680
gene id: 189425:PGRAT_RS25680
uniprot id: A0A089MAK6
names: Similarity
messages: Belongs to the thioredoxin family.

189425:PGRAT RS04230
gene id: 189425:PGRAT_RS04230
uniprot id: A0A089NDC8
names: Subcellular Location Annotation
messages: Membrane

189425:PGRAT RS08805
gene id: 189425:PGRAT_RS08805
uniprot id: A0A089M8F6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. EmrB family.
messages: Cell membrane
messages: Membrane

189425:PGRAT RS05610
gene id: 189425:PGRAT_RS05610
uniprot id: A0A089M1Y5
names: Similarity
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.

189425:PGRAT RS24755
gene id: 189425:PGRAT_RS24755
uniprot id: A0A089NNM6
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

189425:PGRAT RS02385
gene id: 189425:PGRAT_RS02385
uniprot id: A0A089M0E7
names: Subcellular Location Annotation
messages: Membrane

189425:PGRAT RS14325
gene id: 189425:PGRAT_RS14325
uniprot id: A0A089NIB3
names: Subcellular Location Annotation
messages: Membrane

189425:PGRAT RS30820
gene id: 189425:PGRAT_RS30820
uniprot id: A0A089MEL3
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

189425:PGRAT RS04715
gene id: 189425:PGRAT_RS04715
uniprot id: A0A089LZV3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycosyl hydrolase 2 family.
messages: Homodimer.
messages: Secreted

189425:PGRAT RS01500
gene id: 189425:PGRAT_RS01500
uniprot id: A0A089M4S2
names: Similarity
messages: Belongs to the AlaDH/PNT family.

189425:PGRAT RS01395
gene id: 189425:PGRAT_RS01395
uniprot id: A0A089M4Q8
names: Cofactor
names: Similarity
messages: Belongs to the glycosyl hydrolase 4 family.
messages: Binds 1 NAD(+) per subunit.

189425:PGRAT RS04660
gene id: 189425:PGRAT_RS04660
uniprot id: A0A089M3S5
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-I 3-dehydroquinase family.
messages: Homodimer.
messages: Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3-dehydroshikimate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

189425:PGRAT RS17960
gene id: 189425:PGRAT_RS17960
uniprot id: A0A089MAT9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M32 family.
messages: Binds 1 zinc ion per subunit.
messages: Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues.

189425:PGRAT RS25280
gene id: 189425:PGRAT_RS25280
uniprot id: A0A089MEI9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

189425:PGRAT RS06495
gene id: 189425:PGRAT_RS06495
uniprot id: A0A089M4W3
names: Similarity
messages: Belongs to the OsmC/Ohr family.

189425:PGRAT RS12020
gene id: 189425:PGRAT_RS12020
uniprot id: A0A089M3L6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Amj family.
messages: Cell membrane
messages: Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

189425:PGRAT RS24675
gene id: 189425:PGRAT_RS24675
uniprot id: A0A089NNL0
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

189425:PGRAT RS07640
gene id: 189425:PGRAT_RS07640
uniprot id: A0A089NF04
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

189425:PGRAT RS29860
gene id: 189425:PGRAT_RS29860
uniprot id: A0A089MGQ3
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

189425:PGRAT RS19765
gene id: 189425:PGRAT_RS19765
uniprot id: A0A089MBQ2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

189425:PGRAT RS07470
gene id: 189425:PGRAT_RS07470
uniprot id: A0A089NEX4
names: Similarity
messages: Belongs to the PspA/IM30 family.

189425:PGRAT RS24000
gene id: 189425:PGRAT_RS24000
uniprot id: A0A089MGC5
names: Similarity
messages: Belongs to the zinc-associated anti-sigma factor (ZAS) superfamily. Anti-sigma-W factor family.

189425:PGRAT RS24170
gene id: 189425:PGRAT_RS24170
uniprot id: A0A089ME01
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp).
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

189425:PGRAT RS09335
gene id: 189425:PGRAT_RS09335
uniprot id: A0A089M3X0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

189425:PGRAT RS04890
gene id: 189425:PGRAT_RS04890
uniprot id: A0A089M6E6
names: Similarity
messages: Belongs to the UPF0312 family.

189425:PGRAT RS02550
gene id: 189425:PGRAT_RS02550
uniprot id: A0A089M0G9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

189425:PGRAT RS21500
gene id: 189425:PGRAT_RS21500
uniprot id: A0A089NM24
names: Similarity
messages: Belongs to the DapA family.

189425:PGRAT RS28085
gene id: 189425:PGRAT_RS28085
uniprot id: A0A089NQ96
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

189425:PGRAT RS23395
gene id: 189425:PGRAT_RS23395
uniprot id: A0A089MAZ7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

189425:PGRAT RS30830
gene id: 189425:PGRAT_RS30830
uniprot id: A0A089NRN7
names: Subcellular Location Annotation
messages: Membrane

189425:PGRAT RS03935
gene id: 189425:PGRAT_RS03935
uniprot id: A0A089M639
names: Subcellular Location Annotation
messages: Membrane

189425:PGRAT RS29115
gene id: 189425:PGRAT_RS29115
uniprot id: A0A089MGF0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

189425:PGRAT RS01605
gene id: 189425:PGRAT_RS01605
uniprot id: A0A089LYA6
names: Similarity
messages: Belongs to the UPF0065 (bug) family.

189425:PGRAT RS23295
gene id: 189425:PGRAT_RS23295
uniprot id: A0A089MAY3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

189425:PGRAT RS12325
gene id: 189425:PGRAT_RS12325
uniprot id: A0A089M3S4
names: Function
names: Subunit
messages: Counteracts the endogenous Pycsar antiviral defense system. Phosphodiesterase that enables metal-dependent hydrolysis of host cyclic nucleotide Pycsar defense signals such as cCMP and cUMP.
messages: Homodimer.

189425:PGRAT RS00020
gene id: 189425:PGRAT_RS00020
uniprot id: A0A089M3Y1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

189425:PGRAT RS02775
gene id: 189425:PGRAT_RS02775
uniprot id: A0A089LYU5
names: Similarity
messages: Belongs to the UPF0337 (CsbD) family.

189425:PGRAT RS12830
gene id: 189425:PGRAT_RS12830
uniprot id: A0A089M5L8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

189425:PGRAT RS13975
gene id: 189425:PGRAT_RS13975
uniprot id: A0A089M4K4
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

189425:PGRAT RS19675
gene id: 189425:PGRAT_RS19675
uniprot id: A0A089ME70
names: Similarity
messages: Belongs to the AAA ATPase family.
messages: In the C-terminal section; belongs to the peptidase M41 family.

189425:PGRAT RS15215
gene id: 189425:PGRAT_RS15215
uniprot id: A0A089NIT8
names: Similarity
messages: Belongs to the peptidase S33 family.

189425:PGRAT RS21520
gene id: 189425:PGRAT_RS21520
uniprot id: A0A089MF55
names: Subcellular Location Annotation
messages: Membrane

189425:PGRAT RS11795
gene id: 189425:PGRAT_RS11795
uniprot id: A0A089NH23
names: Cofactor
names: Similarity
messages: Belongs to the iron-containing alcohol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.

189425:PGRAT RS28285
gene id: 189425:PGRAT_RS28285
uniprot id: A0A089MFY2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
messages: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.
messages: Homodimer.

189425:PGRAT RS13155
gene id: 189425:PGRAT_RS13155
uniprot id: A0A089M876
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

189425:PGRAT RS18820
gene id: 189425:PGRAT_RS18820
uniprot id: A0A089M8N5
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane
messages: Membrane

189425:PGRAT RS19185
gene id: 189425:PGRAT_RS19185
uniprot id: A0A089MBE0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Alpha(8)-beta(8). The alpha component is a flavoprotein, the beta component is a hemoprotein.
messages: Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Binds 1 siroheme per subunit.
messages: Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate.

189425:PGRAT RS15420
gene id: 189425:PGRAT_RS15420
uniprot id: A0A089NIX0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family. MepA subfamily.
messages: Cell membrane

189425:PGRAT RS13955
gene id: 189425:PGRAT_RS13955
uniprot id: A0A089M648
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsX family.
messages: Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
messages: Cytoplasm
messages: Homodimer. Probably interacts with PlsY.

189425:PGRAT RS27805
gene id: 189425:PGRAT_RS27805
uniprot id: A0A089NQ28
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

189425:PGRAT RS17680
gene id: 189425:PGRAT_RS17680
uniprot id: A0A089M859
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliR/MopE/SpaR family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

189425:PGRAT RS25140
gene id: 189425:PGRAT_RS25140
uniprot id: A0A089MGY1
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

189425:PGRAT RS21580
gene id: 189425:PGRAT_RS21580
uniprot id: A0A089MCN0
names: Subcellular Location Annotation
messages: Membrane

189425:PGRAT RS15705
gene id: 189425:PGRAT_RS15705
uniprot id: A0A089M5G7
names: Cofactor
names: Similarity
messages: Belongs to the rubredoxin family.
messages: Binds 1 Fe(3+) ion per subunit.

189425:PGRAT RS28290
gene id: 189425:PGRAT_RS28290
uniprot id: A0A089MBS9
names: Subcellular Location Annotation
messages: Membrane

189425:PGRAT RS19900
gene id: 189425:PGRAT_RS19900
uniprot id: A0A089M7N6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

189425:PGRAT RS06010
gene id: 189425:PGRAT_RS06010
uniprot id: A0A089NE76
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

189425:PGRAT RS12605
gene id: 189425:PGRAT_RS12605
uniprot id: A0A089MAI9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

189425:PGRAT RS06470
gene id: 189425:PGRAT_RS06470
uniprot id: A0A089M0U6
names: Subcellular Location Annotation
messages: Membrane

189425:PGRAT RS24505
gene id: 189425:PGRAT_RS24505
uniprot id: A0A089NNH3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

189425:PGRAT RS20330
gene id: 189425:PGRAT_RS20330
uniprot id: A0A089NLJ8
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the ferredoxin--NADP reductase type 2 family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

189425:PGRAT RS28345
gene id: 189425:PGRAT_RS28345
uniprot id: A0A089MBU0
names: Similarity
messages: Belongs to the MotB family.

189425:PGRAT RS14635
gene id: 189425:PGRAT_RS14635
uniprot id: A0A089M4Y2
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

189425:PGRAT RS07865
gene id: 189425:PGRAT_RS07865
uniprot id: A0A089M1J8
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

189425:PGRAT RS22550
gene id: 189425:PGRAT_RS22550
uniprot id: A0A089MD55
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

189425:PGRAT RS29745
gene id: 189425:PGRAT_RS29745
uniprot id: A0A089MJ50
names: Similarity
messages: Belongs to the glycosyl hydrolase 8 (cellulase D) family.

189425:PGRAT RS08935
gene id: 189425:PGRAT_RS08935
uniprot id: A0A089M8I0
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

189425:PGRAT RS00470
gene id: 189425:PGRAT_RS00470
uniprot id: A0A089NBM4
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

189425:PGRAT RS27925
gene id: 189425:PGRAT_RS27925
uniprot id: A0A089MI77
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

189425:PGRAT RS29055
gene id: 189425:PGRAT_RS29055
uniprot id: A0A089MGE5
names: Similarity
messages: Belongs to the formate--tetrahydrofolate ligase family.

189425:PGRAT RS09830
gene id: 189425:PGRAT_RS09830
uniprot id: A0A089M463
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

189425:PGRAT RS17925
gene id: 189425:PGRAT_RS17925
uniprot id: A0A089MDC8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

189425:PGRAT RS33865
gene id: 189425:PGRAT_RS33865
uniprot id: A0A089NRU0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family. SbnA subfamily.
messages: Catalyzes the synthesis of N-((2S)-2-amino-2-carboxyethyl)-L-glutamate (ACEGA) from O-phospho-L-serine and L-glutamate. Involved in the biosynthesis of L-2,3-diaminopropionic acid (L-Dap), a precursor of staphyloferrin B and antibiotics.
messages: Homodimer.

189425:PGRAT RS29150
gene id: 189425:PGRAT_RS29150
uniprot id: A0A089MDU5
names: Subcellular Location Annotation
messages: Membrane

189425:PGRAT RS06240
gene id: 189425:PGRAT_RS06240
uniprot id: A0A089M0P6
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

189425:PGRAT RS28050
gene id: 189425:PGRAT_RS28050
uniprot id: A0A089MD64
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

189425:PGRAT RS19690
gene id: 189425:PGRAT_RS19690
uniprot id: A0A089M7J0
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. MTA/SAH deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L-homocysteine, respectively. Is also able to deaminate adenosine.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

189425:PGRAT RS09035
gene id: 189425:PGRAT_RS09035
uniprot id: A0A089M3P7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

189425:PGRAT RS10780
gene id: 189425:PGRAT_RS10780
uniprot id: A0A089M4J9
names: Subcellular Location Annotation
messages: Cell membrane

189425:PGRAT RS15140
gene id: 189425:PGRAT_RS15140
uniprot id: A0A089NIS7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. EmrB family.
messages: Cell membrane
messages: Membrane

189425:PGRAT RS29010
gene id: 189425:PGRAT_RS29010
uniprot id: A0A089MDS4
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

189425:PGRAT RS13385
gene id: 189425:PGRAT_RS13385
uniprot id: A0A089M8C5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

189425:PGRAT RS00145
gene id: 189425:PGRAT_RS00145
uniprot id: A0A089NBH2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ribonuclease M5 family.
messages: Cytoplasm
messages: Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step.

189425:PGRAT RS22660
gene id: 189425:PGRAT_RS22660
uniprot id: A0A089MAK8
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

189425:PGRAT RS05100
gene id: 189425:PGRAT_RS05100
uniprot id: A0A089NDQ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Membrane

189425:PGRAT RS06715
gene id: 189425:PGRAT_RS06715
uniprot id: A0A089M119
names: Function
names: Subunit
messages: Counteracts the endogenous Pycsar antiviral defense system. Phosphodiesterase that enables metal-dependent hydrolysis of host cyclic nucleotide Pycsar defense signals such as cCMP and cUMP.
messages: Homodimer.

189425:PGRAT RS19840
gene id: 189425:PGRAT_RS19840
uniprot id: A0A089NL80
names: Similarity
messages: Belongs to the prephenate/arogenate dehydrogenase family.

189425:PGRAT RS14400
gene id: 189425:PGRAT_RS14400
uniprot id: A0A089M6D7
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

189425:PGRAT RS26220
gene id: 189425:PGRAT_RS26220
uniprot id: A0A089MCF0
names: Similarity
messages: Belongs to the peptidase C40 family.

189425:PGRAT RS23640
gene id: 189425:PGRAT_RS23640
uniprot id: A0A089M9L3
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

189425:PGRAT RS00825
gene id: 189425:PGRAT_RS00825
uniprot id: A0A089M1T1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ThiC family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

189425:PGRAT RS29900
gene id: 189425:PGRAT_RS29900
uniprot id: A0A089ME51
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.

189425:PGRAT RS05915
gene id: 189425:PGRAT_RS05915
uniprot id: A0A089M0H7
names: Similarity
messages: Belongs to the AHA1 family.

189425:PGRAT RS26625
gene id: 189425:PGRAT_RS26625
uniprot id: A0A089MHN4
names: Subcellular Location Annotation
messages: Membrane

189425:PGRAT RS20290
gene id: 189425:PGRAT_RS20290
uniprot id: A0A089M7Z8
names: Similarity
messages: Belongs to the type-B carboxylesterase/lipase family.

189425:PGRAT RS27825
gene id: 189425:PGRAT_RS27825
uniprot id: A0A089MI54
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

189425:PGRAT RS00150
gene id: 189425:PGRAT_RS00150
uniprot id: A0A089M1F2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

189425:PGRAT RS21490
gene id: 189425:PGRAT_RS21490
uniprot id: A0A089MA26
names: Similarity
messages: Belongs to the IlvD/Edd family.

189425:PGRAT RS08905
gene id: 189425:PGRAT_RS08905
uniprot id: A0A089NFN2
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

189425:PGRAT RS01515
gene id: 189425:PGRAT_RS01515
uniprot id: A0A089LY95
names: Similarity
messages: Belongs to the alpha/beta-type SASP family.

189425:PGRAT RS06160
gene id: 189425:PGRAT_RS06160
uniprot id: A0A089M4L4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

189425:PGRAT RS20615
gene id: 189425:PGRAT_RS20615
uniprot id: A0A089MES9
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

189425:PGRAT RS26680
gene id: 189425:PGRAT_RS26680
uniprot id: A0A089MB30
names: Subcellular Location Annotation
messages: Membrane

189425:PGRAT RS12095
gene id: 189425:PGRAT_RS12095
uniprot id: A0A089M3N3
names: Similarity
messages: Belongs to the glycosyl hydrolase 9 (cellulase E) family.

189425:PGRAT RS06870
gene id: 189425:PGRAT_RS06870
uniprot id: A0A089M2P6
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

189425:PGRAT RS16155
gene id: 189425:PGRAT_RS16155
uniprot id: A0A089MCA1
names: Subcellular Location Annotation
messages: Membrane

189425:PGRAT RS01540
gene id: 189425:PGRAT_RS01540
uniprot id: A0A089M276
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

189425:PGRAT RS02520
gene id: 189425:PGRAT_RS02520
uniprot id: A0A089M578
names: Similarity
messages: Belongs to the glycosyl hydrolase 30 family.

189425:PGRAT RS18800
gene id: 189425:PGRAT_RS18800
uniprot id: A0A089MDN8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

189425:PGRAT RS13990
gene id: 189425:PGRAT_RS13990
uniprot id: A0A089NI46
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.

189425:PGRAT RS07925
gene id: 189425:PGRAT_RS07925
uniprot id: A0A089NF53
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

189425:PGRAT RS07130
gene id: 189425:PGRAT_RS07130
uniprot id: A0A089M552
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

189425:PGRAT RS24370
gene id: 189425:PGRAT_RS24370
uniprot id: A0A089MGJ0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KdpA family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds the extracellular potassium ions and delivers the ions to the membrane domain of KdpB through an intramembrane tunnel.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

189425:PGRAT RS02040
gene id: 189425:PGRAT_RS02040
uniprot id: A0A089M2E5
names: Similarity
messages: Belongs to the CAPAB/TerDEXZ family.

189425:PGRAT RS15960
gene id: 189425:PGRAT_RS15960
uniprot id: A0A089M5L7
names: Similarity
messages: Belongs to the peptidase M29 family.

189425:PGRAT RS24905
gene id: 189425:PGRAT_RS24905
uniprot id: A0A089MA81
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane

189425:PGRAT RS23925
gene id: 189425:PGRAT_RS23925
uniprot id: A0A089NN83
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

189425:PGRAT RS12765
gene id: 189425:PGRAT_RS12765
uniprot id: A0A089M822
names: Similarity
messages: Belongs to the helicase family. RAD25/XPB subfamily.

189425:PGRAT RS16960
gene id: 189425:PGRAT_RS16960
uniprot id: A0A089M7R0
names: Function
names: Similarity
messages: Belongs to the MoaB/Mog family.
messages: May be involved in the biosynthesis of molybdopterin.

189425:PGRAT RS07650
gene id: 189425:PGRAT_RS07650
uniprot id: A0A089M1H0
names: Subcellular Location Annotation
messages: Membrane

189425:PGRAT RS11240
gene id: 189425:PGRAT_RS11240
uniprot id: A0A089M366
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the uroporphyrinogen decarboxylase family.
messages: Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

189425:PGRAT RS06555
gene id: 189425:PGRAT_RS06555
uniprot id: A0A089M0Z4
names: Similarity
messages: Belongs to the peptidase A24 family.

189425:PGRAT RS12130
gene id: 189425:PGRAT_RS12130
uniprot id: A0A089M3Q3
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

189425:PGRAT RS30355
gene id: 189425:PGRAT_RS30355
uniprot id: A0A089MED3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RacA family.
messages: Cytoplasm
messages: Required for the formation of axial filaments and for anchoring the origin regions at the cell poles in sporulating cells, thus ensuring proper chromosome segregation in the prespore. Binds in a dispersed manner throughout the chromosome but preferentially to sites clustered in the origin portion of the chromosome, causing condensation of the chromosome and its remodeling into an elongated, anchored structure.

189425:PGRAT RS24655
gene id: 189425:PGRAT_RS24655
uniprot id: A0A089ME69
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HMBS family.
messages: Binds 1 dipyrromethane group covalently.
messages: Monomer.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
messages: The porphobilinogen subunits are added to the dipyrromethane group.

189425:PGRAT RS03610
gene id: 189425:PGRAT_RS03610
uniprot id: A0A089ND20
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

189425:PGRAT RS25910
gene id: 189425:PGRAT_RS25910
uniprot id: A0A089MCB4
names: Similarity
messages: Belongs to the truncated hemoglobin family. Group II subfamily.

189425:PGRAT RS17250
gene id: 189425:PGRAT_RS17250
uniprot id: A0A089M6A3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the metal hydrolase YfiT family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Possible metal-dependent hydrolase.

189425:PGRAT RS25630
gene id: 189425:PGRAT_RS25630
uniprot id: A0A089MAJ6
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.

189425:PGRAT RS11955
gene id: 189425:PGRAT_RS11955
uniprot id: A0A089MA27
names: Subcellular Location Annotation
messages: Membrane

189425:PGRAT RS07295
gene id: 189425:PGRAT_RS07295
uniprot id: A0A089M577
names: Similarity
messages: Belongs to the BMP lipoprotein family.

189425:PGRAT RS29505
gene id: 189425:PGRAT_RS29505
uniprot id: A0A089MJ25
names: Subcellular Location Annotation
messages: Membrane

189425:PGRAT RS16865
gene id: 189425:PGRAT_RS16865
uniprot id: A0A089MA68
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

189425:PGRAT RS17810
gene id: 189425:PGRAT_RS17810
uniprot id: A0A089M878
names: Similarity
messages: Belongs to the DprA/Smf family.

189425:PGRAT RS05710
gene id: 189425:PGRAT_RS05710
uniprot id: A0A089M202
names: Similarity
messages: Belongs to the DinB family.

189425:PGRAT RS28580
gene id: 189425:PGRAT_RS28580
uniprot id: A0A089MG41
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

189425:PGRAT RS25775
gene id: 189425:PGRAT_RS25775
uniprot id: A0A089MET2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

189425:PGRAT RS23935
gene id: 189425:PGRAT_RS23935
uniprot id: A0A089M9R1
names: Function
names: Similarity
messages: Belongs to the HrcA family.
messages: Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons.

189425:PGRAT RS14925
gene id: 189425:PGRAT_RS14925
uniprot id: A0A089M999
names: Subcellular Location Annotation
messages: Membrane

189425:PGRAT RS28360
gene id: 189425:PGRAT_RS28360
uniprot id: A0A089NQF5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family. N-terminal subunit subfamily.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H. In this organism, the P 'protein' is a heterodimer of two subunits.

189425:PGRAT RS14450
gene id: 189425:PGRAT_RS14450
uniprot id: A0A089M4V0
names: Subcellular Location Annotation
messages: Membrane

189425:PGRAT RS11685
gene id: 189425:PGRAT_RS11685
uniprot id: A0A089M3E4
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

189425:PGRAT RS23765
gene id: 189425:PGRAT_RS23765
uniprot id: A0A089M9N2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. AddB/RexB type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster.
messages: Heterodimer of AddA and AddB.
messages: The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddB nuclease domain is not required for chi fragment generation; this subunit has 5' -> 3' nuclease activity.

189425:PGRAT RS14135
gene id: 189425:PGRAT_RS14135
uniprot id: A0A089MB96
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. EmrB family.
messages: Cell membrane
messages: Membrane

189425:PGRAT RS03570
gene id: 189425:PGRAT_RS03570
uniprot id: A0A089LZ99
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

189425:PGRAT RS31050
gene id: 189425:PGRAT_RS31050
uniprot id: A0A089MEP9
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

189425:PGRAT RS05315
gene id: 189425:PGRAT_RS05315
uniprot id: A0A089M441
names: Similarity
messages: Belongs to the UDPGP type 2 family.

189425:PGRAT RS29805
gene id: 189425:PGRAT_RS29805
uniprot id: A0A089NR38
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

189425:PGRAT RS06520
gene id: 189425:PGRAT_RS06520
uniprot id: A0A089NEI4
names: Similarity
messages: Belongs to the GSP E family.

189425:PGRAT RS00080
gene id: 189425:PGRAT_RS00080
uniprot id: A0A089LXG0
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-I family.

189425:PGRAT RS21485
gene id: 189425:PGRAT_RS21485
uniprot id: A0A089M8I6
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

189425:PGRAT RS01170
gene id: 189425:PGRAT_RS01170
uniprot id: A0A089LZW2
names: Similarity
messages: Belongs to the AfsR/DnrI/RedD regulatory family.

189425:PGRAT RS18880
gene id: 189425:PGRAT_RS18880
uniprot id: A0A089NKN0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LTA synthase family.
messages: Cell membrane
messages: Membrane

189425:PGRAT RS20025
gene id: 189425:PGRAT_RS20025
uniprot id: A0A089M7R2
names: Similarity
messages: Belongs to the MecA family.

189425:PGRAT RS09425
gene id: 189425:PGRAT_RS09425
uniprot id: A0A089M3Z7
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

189425:PGRAT RS00175
gene id: 189425:PGRAT_RS00175
uniprot id: A0A089M1F9
names: Similarity
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.

189425:PGRAT RS28870
gene id: 189425:PGRAT_RS28870
uniprot id: A0A089MDQ2
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

189425:PGRAT RS21590
gene id: 189425:PGRAT_RS21590
uniprot id: A0A089MA45
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Uronate isomerase family.

189425:PGRAT RS03235
gene id: 189425:PGRAT_RS03235
uniprot id: A0A089M5P0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Belongs to the P-Pant transferase superfamily. Gsp/Sfp/HetI/AcpT family.
messages: Cytoplasm
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

189425:PGRAT RS05110
gene id: 189425:PGRAT_RS05110
uniprot id: A0A089M020
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 2 family.
messages: Cell membrane
messages: Membrane

189425:PGRAT RS23730
gene id: 189425:PGRAT_RS23730
uniprot id: A0A089NN56
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

189425:PGRAT RS24600
gene id: 189425:PGRAT_RS24600
uniprot id: A0A089MA28
names: Similarity
messages: Belongs to the folylpolyglutamate synthase family.

189425:PGRAT RS24645
gene id: 189425:PGRAT_RS24645
uniprot id: A0A089MGN8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Catalyzes an early step in the biosynthesis of tetrapyrroles. Binds two molecules of 5-aminolevulinate per subunit, each at a distinct site, and catalyzes their condensation to form porphobilinogen.
messages: Homooctamer.

189425:PGRAT RS28480
gene id: 189425:PGRAT_RS28480
uniprot id: A0A089MDF0
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArgJ family.
messages: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.
messages: Cytoplasm
messages: Heterotetramer of two alpha and two beta chains.
messages: Some bacteria possess a monofunctional ArgJ, i.e., capable of catalyzing only the fifth step of the arginine biosynthetic pathway.

189425:PGRAT RS03955
gene id: 189425:PGRAT_RS03955
uniprot id: A0A089M190
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

189425:PGRAT RS24935
gene id: 189425:PGRAT_RS24935
uniprot id: A0A089MBQ0
names: Subcellular Location Annotation
messages: Membrane

189425:PGRAT RS15900
gene id: 189425:PGRAT_RS15900
uniprot id: A0A089NJ35
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

189425:PGRAT RS07350
gene id: 189425:PGRAT_RS07350
uniprot id: A0A089M1C1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferrochelatase family.
messages: Cytoplasm
messages: Involved in coproporphyrin-dependent heme b biosynthesis. Catalyzes the insertion of ferrous iron into coproporphyrin III to form Fe-coproporphyrin III.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

189425:PGRAT RS16435
gene id: 189425:PGRAT_RS16435
uniprot id: A0A089M7G6
names: Similarity
messages: Belongs to the type IA topoisomerase family.

189425:PGRAT RS26670
gene id: 189425:PGRAT_RS26670
uniprot id: A0A089NPL3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

189425:PGRAT RS02880
gene id: 189425:PGRAT_RS02880
uniprot id: A0A089M2V4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Membrane

189425:PGRAT RS26510
gene id: 189425:PGRAT_RS26510
uniprot id: A0A089MB03
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nlpA lipoprotein family.
messages: Membrane

189425:PGRAT RS09095
gene id: 189425:PGRAT_RS09095
uniprot id: A0A089M8L7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sirtuin family. Class U subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form.

189425:PGRAT RS15800
gene id: 189425:PGRAT_RS15800
uniprot id: A0A089NJ19
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family.
messages: Cell membrane
messages: Membrane

189425:PGRAT RS00180
gene id: 189425:PGRAT_RS00180
uniprot id: A0A089LXI3
names: Function
names: Similarity
messages: Belongs to the SpoVG family.
messages: Could be involved in septation.

189425:PGRAT RS11340
gene id: 189425:PGRAT_RS11340
uniprot id: A0A089M795
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by ADP and other diphosphonucleosides, and allosterically inhibited by phosphoenolpyruvate.
messages: Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Prokaryotic clade 'B1' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

189425:PGRAT RS09215
gene id: 189425:PGRAT_RS09215
uniprot id: A0A089M3T1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA mismatch repair MutS family. MutS2 subfamily.
messages: Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity.
messages: Homodimer.

189425:PGRAT RS26175
gene id: 189425:PGRAT_RS26175
uniprot id: A0A089NPE8
names: Subcellular Location Annotation
messages: Membrane

189425:PGRAT RS11115
gene id: 189425:PGRAT_RS11115
uniprot id: A0A089M4Q2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

189425:PGRAT RS05510
gene id: 189425:PGRAT_RS05510
uniprot id: A0A089M1W9
names: Function
names: Similarity
messages: Belongs to the 2H phosphoesterase superfamily. ThpR family.
messages: Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'-phosphomonoester.

189425:PGRAT RS30960
gene id: 189425:PGRAT_RS30960
uniprot id: A0A089MHA7
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with bS18 to 16S ribosomal RNA.

189425:PGRAT RS16970
gene id: 189425:PGRAT_RS16970
uniprot id: A0A089MCR2
names: Subcellular Location Annotation
messages: Membrane

189425:PGRAT RS29380
gene id: 189425:PGRAT_RS29380
uniprot id: A0A089MCE0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BioY family.
messages: Cell membrane

189425:PGRAT RS17685
gene id: 189425:PGRAT_RS17685
uniprot id: A0A089MD92
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliQ/MopD/SpaQ family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

189425:PGRAT RS21470
gene id: 189425:PGRAT_RS21470
uniprot id: A0A089MF44
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

189425:PGRAT RS27840
gene id: 189425:PGRAT_RS27840
uniprot id: A0A089MBJ7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

189425:PGRAT RS18125
gene id: 189425:PGRAT_RS18125
uniprot id: A0A089M8D2
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.

189425:PGRAT RS06650
gene id: 189425:PGRAT_RS06650
uniprot id: A0A089NEK5
names: Function
names: Similarity
messages: Belongs to the nucleoside phosphorylase PpnP family.
messages: Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions.

189425:PGRAT RS24220
gene id: 189425:PGRAT_RS24220
uniprot id: A0A089ME11
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Cell membrane
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

189425:PGRAT RS19530
gene id: 189425:PGRAT_RS19530
uniprot id: A0A089MBK5
names: Subcellular Location Annotation
messages: Membrane

189425:PGRAT RS30905
gene id: 189425:PGRAT_RS30905
uniprot id: A0A089NRQ5
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity.

189425:PGRAT RS14695
gene id: 189425:PGRAT_RS14695
uniprot id: A0A089M6K2
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

189425:PGRAT RS17850
gene id: 189425:PGRAT_RS17850
uniprot id: A0A089NK87
names: Similarity
messages: Belongs to the UPF0102 family.

189425:PGRAT RS17585
gene id: 189425:PGRAT_RS17585
uniprot id: A0A089MD74
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

189425:PGRAT RS34090
gene id: 189425:PGRAT_RS34090
uniprot id: A0A089MDR6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

189425:PGRAT RS04355
gene id: 189425:PGRAT_RS04355
uniprot id: A0A089M1E8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

189425:PGRAT RS00895
gene id: 189425:PGRAT_RS00895
uniprot id: A0A089M4F4
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

189425:PGRAT RS24835
gene id: 189425:PGRAT_RS24835
uniprot id: A0A089NNP5
names: Similarity
messages: Belongs to the CpsD/CapB family.

189425:PGRAT RS24850
gene id: 189425:PGRAT_RS24850
uniprot id: A0A089MBN5
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. CpsB/CapC family.

189425:PGRAT RS09725
gene id: 189425:PGRAT_RS09725
uniprot id: A0A089M903
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 1 family.
messages: Cell membrane

189425:PGRAT RS24770
gene id: 189425:PGRAT_RS24770
uniprot id: A0A089MBM2
names: Similarity
messages: Belongs to the acyltransferase 3 family.

189425:PGRAT RS27800
gene id: 189425:PGRAT_RS27800
uniprot id: A0A089MI47
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAPS reductase family. CysH subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of sulfite from adenosine 5'-phosphosulfate (APS) using thioredoxin as an electron donor.
messages: Cytoplasm

189425:PGRAT RS07800
gene id: 189425:PGRAT_RS07800
uniprot id: A0A089M7X0
names: Function
messages: Involved in some intermediate steps for the synthesis of the antibiotic polyketide bacillaene which is involved in secondary metabolism.

189425:PGRAT RS06855
gene id: 189425:PGRAT_RS06855
uniprot id: A0A089NEM7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobS family.
messages: Cell membrane
messages: Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.
messages: Membrane

189425:PGRAT RS28890
gene id: 189425:PGRAT_RS28890
uniprot id: A0A089MC79
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phospholipase D family. Cardiolipin synthase subfamily.
messages: Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol.
messages: Cell membrane
messages: Membrane

189425:PGRAT RS06490
gene id: 189425:PGRAT_RS06490
uniprot id: A0A089NEH3
names: Similarity
messages: Belongs to the glutathione peroxidase family.

189425:PGRAT RS30235
gene id: 189425:PGRAT_RS30235
uniprot id: A0A089MGX1
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

189425:PGRAT RS05400
gene id: 189425:PGRAT_RS05400
uniprot id: A0A089M070
names: Similarity
messages: Belongs to the Dps family.

189425:PGRAT RS17440
gene id: 189425:PGRAT_RS17440
uniprot id: A0A089NJY8
names: Similarity
messages: Belongs to the SleB family.

189425:PGRAT RS08875
gene id: 189425:PGRAT_RS08875
uniprot id: A0A089M3M4
names: Similarity
messages: Belongs to the glycosyl hydrolase 39 family.

189425:PGRAT RS02435
gene id: 189425:PGRAT_RS02435
uniprot id: A0A089LYP1
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Membrane
messages: Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (CysA), two transmembrane proteins (CysT and CysW) and a solute-binding protein (CysP).

189425:PGRAT RS24230
gene id: 189425:PGRAT_RS24230
uniprot id: A0A089MBD2
names: Subcellular Location Annotation
messages: Membrane

189425:PGRAT RS16390
gene id: 189425:PGRAT_RS16390
uniprot id: A0A089MCE7
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
messages: Homotetramer.
messages: Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

189425:PGRAT RS29385
gene id: 189425:PGRAT_RS29385
uniprot id: A0A089MDX9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Membrane

189425:PGRAT RS19695
gene id: 189425:PGRAT_RS19695
uniprot id: A0A089M938
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transcriptional regulatory Rex family.
messages: Cytoplasm
messages: Homodimer.
messages: Modulates transcription in response to changes in cellular NADH/NAD(+) redox state.

189425:PGRAT RS26845
gene id: 189425:PGRAT_RS26845
uniprot id: A0A089MB40
names: Subcellular Location Annotation
messages: Membrane

189425:PGRAT RS07520
gene id: 189425:PGRAT_RS07520
uniprot id: A0A089NEY5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

189425:PGRAT RS06250
gene id: 189425:PGRAT_RS06250
uniprot id: A0A089M778
names: Function
names: Similarity
messages: Belongs to the PemK/MazF family.
messages: Toxic component of a type II toxin-antitoxin (TA) system.

189425:PGRAT RS09405
gene id: 189425:PGRAT_RS09405
uniprot id: A0A089M8W4
names: Similarity
messages: Belongs to the CobH/CbiC family.

189425:PGRAT RS29235
gene id: 189425:PGRAT_RS29235
uniprot id: A0A089MDV8
names: Subcellular Location Annotation
messages: Membrane

189425:PGRAT RS10980
gene id: 189425:PGRAT_RS10980
uniprot id: A0A089M9H5
names: Subcellular Location Annotation
messages: Membrane

189425:PGRAT RS23400
gene id: 189425:PGRAT_RS23400
uniprot id: A0A089MG43
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

189425:PGRAT RS16995
gene id: 189425:PGRAT_RS16995
uniprot id: A0A089MCR8
names: Function
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.
messages: Transcriptional repressor of xylose-utilizing enzymes.

189425:PGRAT RS09115
gene id: 189425:PGRAT_RS09115
uniprot id: A0A089M3R5
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

189425:PGRAT RS27865
gene id: 189425:PGRAT_RS27865
uniprot id: A0A089MBK2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

189425:PGRAT RS28865
gene id: 189425:PGRAT_RS28865
uniprot id: A0A089MC76
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

189425:PGRAT RS29300
gene id: 189425:PGRAT_RS29300
uniprot id: A0A089MDW6
names: Similarity
messages: Belongs to the dihydropyrimidine dehydrogenase family.

189425:PGRAT RS28770
gene id: 189425:PGRAT_RS28770
uniprot id: A0A089MDK5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

189425:PGRAT RS03700
gene id: 189425:PGRAT_RS03700
uniprot id: A0A089LZD2
names: Similarity
messages: Belongs to the DODA-type extradiol aromatic ring-opening dioxygenase family.

189425:PGRAT RS21920
gene id: 189425:PGRAT_RS21920
uniprot id: A0A089M8R3
names: Similarity
messages: Belongs to the type-B carboxylesterase/lipase family.

189425:PGRAT RS25105
gene id: 189425:PGRAT_RS25105
uniprot id: A0A089MBS3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase PH family.
messages: Homohexameric ring arranged as a trimer of dimers.
messages: Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.

189425:PGRAT RS22140
gene id: 189425:PGRAT_RS22140
uniprot id: A0A089MCY6
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

189425:PGRAT RS08190
gene id: 189425:PGRAT_RS08190
uniprot id: A0A089M1P2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

189425:PGRAT RS19325
gene id: 189425:PGRAT_RS19325
uniprot id: A0A089M7C3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. EmrB family.
messages: Cell membrane
messages: Membrane

189425:PGRAT RS01505
gene id: 189425:PGRAT_RS01505
uniprot id: A0A089NC41
names: Similarity
messages: Belongs to the CdaR family.

189425:PGRAT RS30675
gene id: 189425:PGRAT_RS30675
uniprot id: A0A089MJM2
names: Function
names: Subunit
messages: Counteracts the endogenous Pycsar antiviral defense system. Phosphodiesterase that enables metal-dependent hydrolysis of host cyclic nucleotide Pycsar defense signals such as cCMP and cUMP.
messages: Homodimer.

189425:PGRAT RS07095
gene id: 189425:PGRAT_RS07095
uniprot id: A0A089M7M8
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

189425:PGRAT RS23455
gene id: 189425:PGRAT_RS23455
uniprot id: A0A089NN14
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.

189425:PGRAT RS17835
gene id: 189425:PGRAT_RS17835
uniprot id: A0A089M883
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

189425:PGRAT RS28035
gene id: 189425:PGRAT_RS28035
uniprot id: A0A089NQ83
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

189425:PGRAT RS29485
gene id: 189425:PGRAT_RS29485
uniprot id: A0A089MGJ9
names: Similarity
messages: Belongs to the EamA transporter family.

189425:PGRAT RS07310
gene id: 189425:PGRAT_RS07310
uniprot id: A0A089M7Q5
names: Subcellular Location Annotation
messages: Membrane

189425:PGRAT RS11325
gene id: 189425:PGRAT_RS11325
uniprot id: A0A089M4T9
names: Subcellular Location Annotation
messages: Cytoplasm

189425:PGRAT RS19595
gene id: 189425:PGRAT_RS19595
uniprot id: A0A089M915
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

189425:PGRAT RS03890
gene id: 189425:PGRAT_RS03890
uniprot id: A0A089M3I3
names: Subcellular Location Annotation
messages: Membrane

189425:PGRAT RS13550
gene id: 189425:PGRAT_RS13550
uniprot id: A0A089MAX5
names: Similarity
messages: Belongs to the peptidase M29 family.

189425:PGRAT RS28210
gene id: 189425:PGRAT_RS28210
uniprot id: A0A089MFW9
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

189425:PGRAT RS01045
gene id: 189425:PGRAT_RS01045
uniprot id: A0A089LY30
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

189425:PGRAT RS17075
gene id: 189425:PGRAT_RS17075
uniprot id: A0A089NJR4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FdhD family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH.

189425:PGRAT RS00550
gene id: 189425:PGRAT_RS00550
uniprot id: A0A089NBN7
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.

189425:PGRAT RS14700
gene id: 189425:PGRAT_RS14700
uniprot id: A0A089MBM7
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

189425:PGRAT RS24570
gene id: 189425:PGRAT_RS24570
uniprot id: A0A089MBI6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YhdE subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

189425:PGRAT RS28410
gene id: 189425:PGRAT_RS28410
uniprot id: A0A089MIH8
names: Similarity
messages: Belongs to the peptidase S41A family.

189425:PGRAT RS08185
gene id: 189425:PGRAT_RS08185
uniprot id: A0A089M5N7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

189425:PGRAT RS06390
gene id: 189425:PGRAT_RS06390
uniprot id: A0A089M0T6
names: Function
names: Subunit
messages: Counteracts the endogenous Pycsar antiviral defense system. Phosphodiesterase that enables metal-dependent hydrolysis of host cyclic nucleotide Pycsar defense signals such as cCMP and cUMP.
messages: Homodimer.

189425:PGRAT RS02400
gene id: 189425:PGRAT_RS02400
uniprot id: A0A089M2L5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LDH/MDH superfamily. LDH family.
messages: Catalyzes the conversion of lactate to pyruvate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

189425:PGRAT RS05625
gene id: 189425:PGRAT_RS05625
uniprot id: A0A089M4A6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MoaC family.
messages: Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
messages: Homohexamer; trimer of dimers.

189425:PGRAT RS13610
gene id: 189425:PGRAT_RS13610
uniprot id: A0A089M5Z4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

189425:PGRAT RS16365
gene id: 189425:PGRAT_RS16365
uniprot id: A0A089MCE1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

189425:PGRAT RS30300
gene id: 189425:PGRAT_RS30300
uniprot id: A0A089MCU3
names: Subcellular Location Annotation
messages: Membrane

189425:PGRAT RS17865
gene id: 189425:PGRAT_RS17865
uniprot id: A0A089M887
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

189425:PGRAT RS03270
gene id: 189425:PGRAT_RS03270
uniprot id: A0A089NCW1
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family.
messages: Homopolymer.

189425:PGRAT RS20315
gene id: 189425:PGRAT_RS20315
uniprot id: A0A089M802
names: Similarity
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Spore germination protein (SGP) (TC 2.A.3.9) family.

189425:PGRAT RS29310
gene id: 189425:PGRAT_RS29310
uniprot id: A0A089MJ00
names: Similarity
messages: Belongs to the CdaR family.

189425:PGRAT RS21020
gene id: 189425:PGRAT_RS21020
uniprot id: A0A089M8A6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FNT transporter (TC 2.A.44) family.
messages: Membrane

189425:PGRAT RS03930
gene id: 189425:PGRAT_RS03930
uniprot id: A0A089M189
names: Similarity
messages: Belongs to the beta/gamma-crystallin family.

189425:PGRAT RS22535
gene id: 189425:PGRAT_RS22535
uniprot id: A0A089MAJ3
names: Similarity
messages: Belongs to the UDP-galactopyranose/dTDP-fucopyranose mutase family.

189425:PGRAT RS16780
gene id: 189425:PGRAT_RS16780
uniprot id: A0A089NJK2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Hfq family.
messages: Homohexamer.
messages: RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs.

189425:PGRAT RS06930
gene id: 189425:PGRAT_RS06930
uniprot id: A0A089M7K6
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

189425:PGRAT RS09510
gene id: 189425:PGRAT_RS09510
uniprot id: A0A089M8X6
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Member of the two-component regulatory system NreB/NreC involved in the control of dissimilatory nitrate/nitrite reduction in response to oxygen. NreB functions as a direct oxygen sensor histidine kinase which is autophosphorylated, in the absence of oxygen, probably at the conserved histidine residue, and transfers its phosphate group probably to a conserved aspartate residue of NreC. NreB/NreC activates the expression of the nitrate (narGHJI) and nitrite (nir) reductase operons, as well as the putative nitrate transporter gene narT.
messages: Membrane

189425:PGRAT RS02415
gene id: 189425:PGRAT_RS02415
uniprot id: A0A089M558
names: Similarity
messages: Belongs to the cycloisomerase 2 family.

189425:PGRAT RS17570
gene id: 189425:PGRAT_RS17570
uniprot id: A0A089MAN7
names: Caution
names: Function
names: Similarity
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

189425:PGRAT RS27875
gene id: 189425:PGRAT_RS27875
uniprot id: A0A089MI65
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

189425:PGRAT RS26980
gene id: 189425:PGRAT_RS26980
uniprot id: A0A089NPP1
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

189425:PGRAT RS00005
gene id: 189425:PGRAT_RS00005
uniprot id: A0A089M1C4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

189425:PGRAT RS25235
gene id: 189425:PGRAT_RS25235
uniprot id: A0A089MAC9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

189425:PGRAT RS16595
gene id: 189425:PGRAT_RS16595
uniprot id: A0A089M7J8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. NagD family.
messages: Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro.
messages: Divalent metal ions. Mg(2+) is the most effective.

189425:PGRAT RS07980
gene id: 189425:PGRAT_RS07980
uniprot id: A0A089NF66
names: Subcellular Location Annotation
messages: Membrane

189425:PGRAT RS10600
gene id: 189425:PGRAT_RS10600
uniprot id: A0A089M2W9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

189425:PGRAT RS27525
gene id: 189425:PGRAT_RS27525
uniprot id: A0A089MCY1
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the adenylate cyclase family. DacA/CdaA subfamily.
messages: Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Probably a homodimer.

189425:PGRAT RS28340
gene id: 189425:PGRAT_RS28340
uniprot id: A0A089MFZ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

189425:PGRAT RS24055
gene id: 189425:PGRAT_RS24055
uniprot id: A0A089NNA0
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.

189425:PGRAT RS28295
gene id: 189425:PGRAT_RS28295
uniprot id: A0A089MDB6
names: Similarity
messages: Belongs to the UDPGP type 2 family.

189425:PGRAT RS23745
gene id: 189425:PGRAT_RS23745
uniprot id: A0A089MB50
names: Similarity
messages: Belongs to the alpha-acetolactate decarboxylase family.

189425:PGRAT RS11835
gene id: 189425:PGRAT_RS11835
uniprot id: A0A089M521
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit F family.
messages: Cell membrane
messages: Membrane

189425:PGRAT RS30740
gene id: 189425:PGRAT_RS30740
uniprot id: A0A089MJN3
names: Similarity
messages: Belongs to the UPF0310 family.

189425:PGRAT RS24750
gene id: 189425:PGRAT_RS24750
uniprot id: A0A089MGQ9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
messages: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.
messages: Homodimer.

189425:PGRAT RS17350
gene id: 189425:PGRAT_RS17350
uniprot id: A0A089M6C3
names: Similarity
messages: Belongs to the DEAD box helicase family.

189425:PGRAT RS09875
gene id: 189425:PGRAT_RS09875
uniprot id: A0A089M2L0
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

189425:PGRAT RS15640
gene id: 189425:PGRAT_RS15640
uniprot id: A0A089NIZ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Nitrate/nitrite porter (TC 2.A.1.8) family.
messages: Cell membrane
messages: Membrane

189425:PGRAT RS11825
gene id: 189425:PGRAT_RS11825
uniprot id: A0A089M7I2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit D family.
messages: Membrane

189425:PGRAT RS05445
gene id: 189425:PGRAT_RS05445
uniprot id: A0A089M466
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

189425:PGRAT RS07135
gene id: 189425:PGRAT_RS07135
uniprot id: A0A089M181
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

189425:PGRAT RS10875
gene id: 189425:PGRAT_RS10875
uniprot id: A0A089M4L2
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

189425:PGRAT RS26375
gene id: 189425:PGRAT_RS26375
uniprot id: A0A089MF24
names: Similarity
messages: Belongs to the PspA/IM30 family.

189425:PGRAT RS24980
gene id: 189425:PGRAT_RS24980
uniprot id: A0A089MGV4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

189425:PGRAT RS21810
gene id: 189425:PGRAT_RS21810
uniprot id: A0A089MA76
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 5 family.
messages: Cell membrane
messages: Membrane

189425:PGRAT RS27505
gene id: 189425:PGRAT_RS27505
uniprot id: A0A089NPX9
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

189425:PGRAT RS16110
gene id: 189425:PGRAT_RS16110
uniprot id: A0A089M9T0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DsbB family. BdbC subfamily.
messages: Membrane

189425:PGRAT RS24465
gene id: 189425:PGRAT_RS24465
uniprot id: A0A089MA01
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

189425:PGRAT RS10435
gene id: 189425:PGRAT_RS10435
uniprot id: A0A089M2U0
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

189425:PGRAT RS26535
gene id: 189425:PGRAT_RS26535
uniprot id: A0A089MF47
names: Subcellular Location Annotation
messages: Membrane

189425:PGRAT RS24105
gene id: 189425:PGRAT_RS24105
uniprot id: A0A089MGE0
names: Similarity
messages: Belongs to the SOS response-associated peptidase family.

189425:PGRAT RS23475
gene id: 189425:PGRAT_RS23475
uniprot id: A0A089MG56
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

189425:PGRAT RS15175
gene id: 189425:PGRAT_RS15175
uniprot id: A0A089M585
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

189425:PGRAT RS00400
gene id: 189425:PGRAT_RS00400
uniprot id: A0A089LXN0
names: Function
names: Similarity
messages: Belongs to the peptidase S11 family.
messages: Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors.

189425:PGRAT RS15890
gene id: 189425:PGRAT_RS15890
uniprot id: A0A089M781
names: Subcellular Location Annotation
messages: Membrane

189425:PGRAT RS21305
gene id: 189425:PGRAT_RS21305
uniprot id: A0A089MCI7
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Uronate isomerase family.

189425:PGRAT RS01325
gene id: 189425:PGRAT_RS01325
uniprot id: A0A089M246
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

189425:PGRAT RS24760
gene id: 189425:PGRAT_RS24760
uniprot id: A0A089ME92
names: Subcellular Location Annotation
messages: Membrane

189425:PGRAT RS05860
gene id: 189425:PGRAT_RS05860
uniprot id: A0A089M4F5
names: Function
names: Similarity
messages: Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PDRP subfamily.
messages: Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation/dephosphorylation.

189425:PGRAT RS17210
gene id: 189425:PGRAT_RS17210
uniprot id: A0A089NJU5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

189425:PGRAT RS00310
gene id: 189425:PGRAT_RS00310
uniprot id: A0A089LZC3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

189425:PGRAT RS20945
gene id: 189425:PGRAT_RS20945
uniprot id: A0A089M9T6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

189425:PGRAT RS28455
gene id: 189425:PGRAT_RS28455
uniprot id: A0A089MDE8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm

189425:PGRAT RS30665
gene id: 189425:PGRAT_RS30665
uniprot id: A0A089MD17
names: Similarity
messages: Belongs to the darcynin family.

189425:PGRAT RS13945
gene id: 189425:PGRAT_RS13945
uniprot id: A0A089M8M6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

189425:PGRAT RS06595
gene id: 189425:PGRAT_RS06595
uniprot id: A0A089NEJ4
names: Similarity
messages: Belongs to the GSP E family.

189425:PGRAT RS20540
gene id: 189425:PGRAT_RS20540
uniprot id: A0A089MER5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.
messages: Catalyzes phosphorolysis of the pyrimidine nucleosides uridine, thymidine and 2'-deoxyuridine with the formation of the corresponding pyrimidine base and ribose-1-phosphate.
messages: Homodimer.

189425:PGRAT RS23985
gene id: 189425:PGRAT_RS23985
uniprot id: A0A089MDW7
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

189425:PGRAT RS17200
gene id: 189425:PGRAT_RS17200
uniprot id: A0A089M7V3
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

189425:PGRAT RS19620
gene id: 189425:PGRAT_RS19620
uniprot id: A0A089M922
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 1 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

189425:PGRAT RS19890
gene id: 189425:PGRAT_RS19890
uniprot id: A0A089NL89
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Reduced FMN (FMNH(2)).

189425:PGRAT RS10615
gene id: 189425:PGRAT_RS10615
uniprot id: A0A089NGH4
names: Cofactor
names: Similarity
messages: Belongs to the glycosyl hydrolase 4 family.
messages: Binds 1 NAD(+) per subunit.

189425:PGRAT RS17870
gene id: 189425:PGRAT_RS17870
uniprot id: A0A089MDB9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily.
messages: Cytoplasm
messages: Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity.

189425:PGRAT RS08420
gene id: 189425:PGRAT_RS08420
uniprot id: A0A089M5S9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

189425:PGRAT RS27935
gene id: 189425:PGRAT_RS27935
uniprot id: A0A089MFR3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

189425:PGRAT RS04095
gene id: 189425:PGRAT_RS04095
uniprot id: A0A089M1B2
names: Subcellular Location Annotation
messages: Membrane

189425:PGRAT RS09520
gene id: 189425:PGRAT_RS09520
uniprot id: A0A089M6F2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S1C family.
messages: Cell membrane
messages: Membrane

189425:PGRAT RS06700
gene id: 189425:PGRAT_RS06700
uniprot id: A0A089M7I0
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Membrane
messages: Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (CysA), two transmembrane proteins (CysT and CysW) and a solute-binding protein (CysP).

189425:PGRAT RS23790
gene id: 189425:PGRAT_RS23790
uniprot id: A0A089M9N6
names: Similarity
messages: Belongs to the Nudix hydrolase family.

189425:PGRAT RS28970
gene id: 189425:PGRAT_RS28970
uniprot id: A0A089NQS7
names: Subcellular Location Annotation
messages: Membrane

189425:PGRAT RS20750
gene id: 189425:PGRAT_RS20750
uniprot id: A0A089NLQ7
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

189425:PGRAT RS06645
gene id: 189425:PGRAT_RS06645
uniprot id: A0A089M7H4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family.
messages: Binds 1 Mg(2+) ion per subunit. Can also utilize other divalent metal cations, such as Ca(2+), Mn(2+) and Co(2+).
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
messages: Homodimer.

189425:PGRAT RS03565
gene id: 189425:PGRAT_RS03565
uniprot id: A0A089M388
names: Similarity
messages: Belongs to the type IA topoisomerase family.

189425:PGRAT RS02710
gene id: 189425:PGRAT_RS02710
uniprot id: A0A089M5B0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Membrane

189425:PGRAT RS09310
gene id: 189425:PGRAT_RS09310
uniprot id: A0A089M8Q8
names: Similarity
messages: Belongs to the ArsC family.

189425:PGRAT RS04105
gene id: 189425:PGRAT_RS04105
uniprot id: A0A089NDB1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

189425:PGRAT RS21450
gene id: 189425:PGRAT_RS21450
uniprot id: A0A089NM11
names: Subcellular Location Annotation
messages: Membrane

189425:PGRAT RS29175
gene id: 189425:PGRAT_RS29175
uniprot id: A0A089MCB2
names: Subcellular Location Annotation
messages: Membrane

189425:PGRAT RS15845
gene id: 189425:PGRAT_RS15845
uniprot id: A0A089MC47
names: Cofactor
names: Similarity
messages: Belongs to the glycosyl hydrolase 4 family.
messages: Binds 1 NAD(+) per subunit.

189425:PGRAT RS02615
gene id: 189425:PGRAT_RS02615
uniprot id: A0A089M592
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

189425:PGRAT RS08260
gene id: 189425:PGRAT_RS08260
uniprot id: A0A089M3B0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CotF family.
messages: Spore coat

189425:PGRAT RS05455
gene id: 189425:PGRAT_RS05455
uniprot id: A0A089M1W2
names: Similarity
messages: Belongs to the bacterial solute-binding protein ModA family.

189425:PGRAT RS21200
gene id: 189425:PGRAT_RS21200
uniprot id: A0A089MCG7
names: Function
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family. LacC subfamily.
messages: Belongs to the carbohydrate kinase pfkB family.
messages: Catalyzes the ATP-dependent phosphorylation of fructose-l-phosphate to fructose-l,6-bisphosphate.

189425:PGRAT RS05520
gene id: 189425:PGRAT_RS05520
uniprot id: A0A089NDY3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family.
messages: Membrane

189425:PGRAT RS12415
gene id: 189425:PGRAT_RS12415
uniprot id: A0A089NHC8
names: Subcellular Location Annotation
messages: Membrane

189425:PGRAT RS14180
gene id: 189425:PGRAT_RS14180
uniprot id: A0A089M696
names: Similarity
messages: Belongs to the EamA transporter family.

189425:PGRAT RS27830
gene id: 189425:PGRAT_RS27830
uniprot id: A0A089NQ33
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

189425:PGRAT RS10580
gene id: 189425:PGRAT_RS10580
uniprot id: A0A089M9B7
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

189425:PGRAT RS10310
gene id: 189425:PGRAT_RS10310
uniprot id: A0A089NGB8
names: Function
names: Similarity
messages: Belongs to the LDH/MDH superfamily. LDH family.
messages: Belongs to the LDH/MDH superfamily. MDH type 3 family.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.

189425:PGRAT RS03750
gene id: 189425:PGRAT_RS03750
uniprot id: A0A089LZG7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Mediates influx of magnesium ions.
messages: Membrane

189425:PGRAT RS04815
gene id: 189425:PGRAT_RS04815
uniprot id: A0A089M3V6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

189425:PGRAT RS29035
gene id: 189425:PGRAT_RS29035
uniprot id: A0A089MDS7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

189425:PGRAT RS15740
gene id: 189425:PGRAT_RS15740
uniprot id: A0A089MC35
names: Similarity
messages: Belongs to the beta/gamma-crystallin family.

189425:PGRAT RS12740
gene id: 189425:PGRAT_RS12740
uniprot id: A0A089M818
names: Similarity
messages: Belongs to the asp23 family.

189425:PGRAT RS24010
gene id: 189425:PGRAT_RS24010
uniprot id: A0A089MDX2
names: Similarity
messages: Belongs to the KHG/KDPG aldolase family.

189425:PGRAT RS12655
gene id: 189425:PGRAT_RS12655
uniprot id: A0A089MAJ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).

189425:PGRAT RS09380
gene id: 189425:PGRAT_RS09380
uniprot id: A0A089M6D0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CbiN family.
messages: Cell membrane
messages: Forms an energy-coupling factor (ECF) transporter complex composed of an ATP-binding protein (A component, CbiO), a transmembrane protein (T component, CbiQ) and 2 possible substrate-capture proteins (S components, CbiM and CbiN) of unknown stoichimetry.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import.

189425:PGRAT RS21010
gene id: 189425:PGRAT_RS21010
uniprot id: A0A089NLU4
names: Similarity
messages: Belongs to the glycosyl hydrolase 65 family.

189425:PGRAT RS03500
gene id: 189425:PGRAT_RS03500
uniprot id: A0A089M377
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Cell membrane
messages: Membrane

189425:PGRAT RS25855
gene id: 189425:PGRAT_RS25855
uniprot id: A0A089MAS4
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
messages: Carbon 2 of the heme B porphyrin ring is defined according to the Fischer nomenclature.
messages: Cell membrane
messages: Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
messages: Interacts with CtaA.
messages: Membrane

189425:PGRAT RS01525
gene id: 189425:PGRAT_RS01525
uniprot id: A0A089M4S5
names: Subcellular Location Annotation
messages: Membrane

189425:PGRAT RS27920
gene id: 189425:PGRAT_RS27920
uniprot id: A0A089MD40
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

189425:PGRAT RS03775
gene id: 189425:PGRAT_RS03775
uniprot id: A0A089LZH1
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

189425:PGRAT RS17985
gene id: 189425:PGRAT_RS17985
uniprot id: A0A089MAU3
names: Similarity
messages: Belongs to the peptidase S66 family.

189425:PGRAT RS06695
gene id: 189425:PGRAT_RS06695
uniprot id: A0A089M2L9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane.
messages: Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (CysA), two transmembrane proteins (CysT and CysW) and a solute-binding protein (CysP).

189425:PGRAT RS24880
gene id: 189425:PGRAT_RS24880
uniprot id: A0A089MBP0
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

189425:PGRAT RS19375
gene id: 189425:PGRAT_RS19375
uniprot id: A0A089M7D2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

189425:PGRAT RS17940
gene id: 189425:PGRAT_RS17940
uniprot id: A0A089M6P7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

189425:PGRAT RS25395
gene id: 189425:PGRAT_RS25395
uniprot id: A0A089MAF9
names: Similarity
messages: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.

189425:PGRAT RS00210
gene id: 189425:PGRAT_RS00210
uniprot id: A0A089LZA3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

189425:PGRAT RS25435
gene id: 189425:PGRAT_RS25435
uniprot id: A0A089MBY8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LTA synthase family.
messages: Cell membrane
messages: Membrane

189425:PGRAT RS09805
gene id: 189425:PGRAT_RS09805
uniprot id: A0A089M458
names: Similarity
messages: Belongs to the Dps family.

189425:PGRAT RS04740
gene id: 189425:PGRAT_RS04740
uniprot id: A0A089LZV8
names: Similarity
messages: Belongs to the threonine synthase family.

189425:PGRAT RS13060
gene id: 189425:PGRAT_RS13060
uniprot id: A0A089M864
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. AraH/RbsC subfamily.
messages: Membrane
messages: Part of the binding-protein-dependent transport system for D-xylose. Probably responsible for the translocation of the substrate across the membrane.

189425:PGRAT RS28860
gene id: 189425:PGRAT_RS28860
uniprot id: A0A089MGC4
names: Caution
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

189425:PGRAT RS14245
gene id: 189425:PGRAT_RS14245
uniprot id: A0A089NI96
names: Similarity
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Spore germination protein (SGP) (TC 2.A.3.9) family.

189425:PGRAT RS23960
gene id: 189425:PGRAT_RS23960
uniprot id: A0A089MDW2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

189425:PGRAT RS09995
gene id: 189425:PGRAT_RS09995
uniprot id: A0A089NG62
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

189425:PGRAT RS28030
gene id: 189425:PGRAT_RS28030
uniprot id: A0A089MIA0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

189425:PGRAT RS18670
gene id: 189425:PGRAT_RS18670
uniprot id: A0A089NKJ1
names: Similarity
messages: Belongs to the arginase family.

189425:PGRAT RS03275
gene id: 189425:PGRAT_RS03275
uniprot id: A0A089M336
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.

189425:PGRAT RS11090
gene id: 189425:PGRAT_RS11090
uniprot id: A0A089M4P7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0718 family.
messages: Cell membrane
messages: Membrane

189425:PGRAT RS07340
gene id: 189425:PGRAT_RS07340
uniprot id: A0A089NEV3
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family.

189425:PGRAT RS02460
gene id: 189425:PGRAT_RS02460
uniprot id: A0A089LYP7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Belongs to the NnrE/AIBP family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.

189425:PGRAT RS14520
gene id: 189425:PGRAT_RS14520
uniprot id: A0A089NIF2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

189425:PGRAT RS13415
gene id: 189425:PGRAT_RS13415
uniprot id: A0A089M8D0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 3 family.
messages: Cell membrane
messages: Membrane

189425:PGRAT RS14590
gene id: 189425:PGRAT_RS14590
uniprot id: A0A089M6H8
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

189425:PGRAT RS29250
gene id: 189425:PGRAT_RS29250
uniprot id: A0A089NQW3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetate uptake transporter (AceTr) (TC 2.A.96) family.
messages: Membrane

189425:PGRAT RS15860
gene id: 189425:PGRAT_RS15860
uniprot id: A0A089M5J8
names: Subcellular Location Annotation
messages: Membrane

189425:PGRAT RS08855
gene id: 189425:PGRAT_RS08855
uniprot id: A0A089M8G9
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

189425:PGRAT RS29045
gene id: 189425:PGRAT_RS29045
uniprot id: A0A089MIW9
names: Subcellular Location Annotation
messages: Membrane

189425:PGRAT RS15555
gene id: 189425:PGRAT_RS15555
uniprot id: A0A089NIY7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

189425:PGRAT RS00370
gene id: 189425:PGRAT_RS00370
uniprot id: A0A089M453
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

189425:PGRAT RS13355
gene id: 189425:PGRAT_RS13355
uniprot id: A0A089NHS1
names: Subcellular Location Annotation
messages: Membrane

189425:PGRAT RS02960
gene id: 189425:PGRAT_RS02960
uniprot id: A0A089NCR3
names: Subcellular Location Annotation
messages: Membrane

189425:PGRAT RS01140
gene id: 189425:PGRAT_RS01140
uniprot id: A0A089M4M6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

189425:PGRAT RS22210
gene id: 189425:PGRAT_RS22210
uniprot id: A0A089MAD5
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

189425:PGRAT RS00435
gene id: 189425:PGRAT_RS00435
uniprot id: A0A089LZE2
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

189425:PGRAT RS04370
gene id: 189425:PGRAT_RS04370
uniprot id: A0A089M3P6
names: Similarity
messages: Belongs to the ABC transporter superfamily.

189425:PGRAT RS24830
gene id: 189425:PGRAT_RS24830
uniprot id: A0A089MGS5
names: Similarity
messages: Belongs to the polysaccharide synthase family.

189425:PGRAT RS15725
gene id: 189425:PGRAT_RS15725
uniprot id: A0A089M9K8
names: Subcellular Location Annotation
messages: cytosol

189425:PGRAT RS24350
gene id: 189425:PGRAT_RS24350
uniprot id: A0A089NNE8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

189425:PGRAT RS29415
gene id: 189425:PGRAT_RS29415
uniprot id: A0A089MDY3
names: Subcellular Location Annotation
messages: Membrane

189425:PGRAT RS30955
gene id: 189425:PGRAT_RS30955
uniprot id: A0A089NRR5
names: Caution
names: Function
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.

189425:PGRAT RS02850
gene id: 189425:PGRAT_RS02850
uniprot id: A0A089NCP6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. Xpt subfamily.
messages: Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis.
messages: Cytoplasm
messages: Homodimer.

189425:PGRAT RS16785
gene id: 189425:PGRAT_RS16785
uniprot id: A0A089MA58
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

189425:PGRAT RS24540
gene id: 189425:PGRAT_RS24540
uniprot id: A0A089MA17
names: Function
names: Similarity
messages: ATPase required for the correct placement of the division site. Cell division inhibitors MinC and MinD act in concert to form an inhibitor capable of blocking formation of the polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings.
messages: Belongs to the ParA family. MinD subfamily.

189425:PGRAT RS17260
gene id: 189425:PGRAT_RS17260
uniprot id: A0A089MCX7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the KduI family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the isomerization of 5-dehydro-4-deoxy-D-glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate.

189425:PGRAT RS27810
gene id: 189425:PGRAT_RS27810
uniprot id: A0A089MFN6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

189425:PGRAT RS11165
gene id: 189425:PGRAT_RS11165
uniprot id: A0A089M352
names: Function
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.
messages: Provides the (R)-glutamate required for cell wall biosynthesis.

189425:PGRAT RS09455
gene id: 189425:PGRAT_RS09455
uniprot id: A0A089M8W9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Mediates influx of magnesium ions.
messages: Membrane

189425:PGRAT RS08745
gene id: 189425:PGRAT_RS08745
uniprot id: A0A089M8E4
names: Similarity
messages: Belongs to the glycosyl hydrolase 130 family.

189425:PGRAT RS19640
gene id: 189425:PGRAT_RS19640
uniprot id: A0A089M7H8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm

189425:PGRAT RS10015
gene id: 189425:PGRAT_RS10015
uniprot id: A0A089M495
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

189425:PGRAT RS10360
gene id: 189425:PGRAT_RS10360
uniprot id: A0A089M987
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

189425:PGRAT RS05345
gene id: 189425:PGRAT_RS05345
uniprot id: A0A089M063
names: Subcellular Location Annotation
messages: Membrane

189425:PGRAT RS31605
gene id: 189425:PGRAT_RS31605
uniprot id: A0A089M5N9
names: Similarity
messages: Belongs to the peptidase C40 family.

189425:PGRAT RS20480
gene id: 189425:PGRAT_RS20480
uniprot id: A0A089M823
names: Similarity
messages: Belongs to the ABC transporter superfamily.

189425:PGRAT RS20550
gene id: 189425:PGRAT_RS20550
uniprot id: A0A089MC66
names: Function
names: Similarity
messages: Belongs to the PNP/MTAP phosphorylase family.
messages: The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.

189425:PGRAT RS05645
gene id: 189425:PGRAT_RS05645
uniprot id: A0A089NE07
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

189425:PGRAT RS05620
gene id: 189425:PGRAT_RS05620
uniprot id: A0A089NE03
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

189425:PGRAT RS20040
gene id: 189425:PGRAT_RS20040
uniprot id: A0A089NLC2
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

189425:PGRAT RS05800
gene id: 189425:PGRAT_RS05800
uniprot id: A0A089NE37
names: Similarity
messages: Belongs to the shaker potassium channel beta subunit family.

189425:PGRAT RS08840
gene id: 189425:PGRAT_RS08840
uniprot id: A0A089M609
names: Similarity
messages: Belongs to the LOG family.

189425:PGRAT RS05820
gene id: 189425:PGRAT_RS05820
uniprot id: A0A089M6X6
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

189425:PGRAT RS17395
gene id: 189425:PGRAT_RS17395
uniprot id: A0A089MAG4
names: Similarity
messages: Belongs to the CinA family.

189425:PGRAT RS16795
gene id: 189425:PGRAT_RS16795
uniprot id: A0A089M7N5
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

189425:PGRAT RS10305
gene id: 189425:PGRAT_RS10305
uniprot id: A0A089M981
names: Cofactor
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

189425:PGRAT RS09720
gene id: 189425:PGRAT_RS09720
uniprot id: A0A089M447
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

189425:PGRAT RS02195
gene id: 189425:PGRAT_RS02195
uniprot id: A0A089M2H4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the alpha-ketoglutarate dehydrogenase family.
messages: E1 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the decarboxylation of 2-oxoglutarate, the first step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).
messages: Homodimer. Part of the 2-oxoglutarate dehydrogenase (OGDH) complex composed of E1 (2-oxoglutarate dehydrogenase), E2 (dihydrolipoamide succinyltransferase) and E3 (dihydrolipoamide dehydrogenase); the complex contains multiple copies of the three enzymatic components (E1, E2 and E3).

189425:PGRAT RS05890
gene id: 189425:PGRAT_RS05890
uniprot id: A0A089M0H3
names: Cofactor
names: Similarity
messages: Belongs to the alkaline phosphatase family.
messages: Binds 1 Mg(2+) ion.
messages: Binds 2 Zn(2+) ions.

189425:PGRAT RS25220
gene id: 189425:PGRAT_RS25220
uniprot id: A0A089MGZ9
names: Subcellular Location Annotation
messages: Membrane

189425:PGRAT RS20320
gene id: 189425:PGRAT_RS20320
uniprot id: A0A089M9J1
names: Similarity
messages: Belongs to the GerABKC lipoprotein family.

189425:PGRAT RS20940
gene id: 189425:PGRAT_RS20940
uniprot id: A0A089M889
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

189425:PGRAT RS20120
gene id: 189425:PGRAT_RS20120
uniprot id: A0A089NLD7
names: Subcellular Location Annotation
messages: Membrane

189425:PGRAT RS24815
gene id: 189425:PGRAT_RS24815
uniprot id: A0A089MEA2
names: Similarity
messages: Belongs to the bacterial sugar transferase family.

189425:PGRAT RS09385
gene id: 189425:PGRAT_RS09385
uniprot id: A0A089M2E3
names: Subcellular Location Annotation
messages: Membrane

189425:PGRAT RS28330
gene id: 189425:PGRAT_RS28330
uniprot id: A0A089MIG4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

189425:PGRAT RS28420
gene id: 189425:PGRAT_RS28420
uniprot id: A0A089MG05
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation.

189425:PGRAT RS30835
gene id: 189425:PGRAT_RS30835
uniprot id: A0A089MH77
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

189425:PGRAT RS27820
gene id: 189425:PGRAT_RS27820
uniprot id: A0A089MD22
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

189425:PGRAT RS06840
gene id: 189425:PGRAT_RS06840
uniprot id: A0A089M136
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

189425:PGRAT RS18030
gene id: 189425:PGRAT_RS18030
uniprot id: A0A089NKB7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

189425:PGRAT RS09155
gene id: 189425:PGRAT_RS09155
uniprot id: A0A089NFS9
names: Subcellular Location Annotation
messages: Membrane

189425:PGRAT RS27885
gene id: 189425:PGRAT_RS27885
uniprot id: A0A089MFQ3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

189425:PGRAT RS16030
gene id: 189425:PGRAT_RS16030
uniprot id: A0A089NJ52
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

189425:PGRAT RS30460
gene id: 189425:PGRAT_RS30460
uniprot id: A0A089MCX4
names: Similarity
messages: Belongs to the CAPAB/TerDEXZ family.

189425:PGRAT RS23585
gene id: 189425:PGRAT_RS23585
uniprot id: A0A089MDP4
names: Similarity
messages: Belongs to the transglycosylase Slt family.

189425:PGRAT RS05435
gene id: 189425:PGRAT_RS05435
uniprot id: A0A089M6N4
names: Similarity
messages: Belongs to the ABC transporter superfamily.

189425:PGRAT RS04750
gene id: 189425:PGRAT_RS04750
uniprot id: A0A089M6C8
names: Similarity
messages: In the N-terminal section; belongs to the NADH:flavin oxidoreductase/NADH oxidase family.

189425:PGRAT RS08590
gene id: 189425:PGRAT_RS08590
uniprot id: A0A089M8A3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein uL14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein uL14 (rplN).

189425:PGRAT RS10400
gene id: 189425:PGRAT_RS10400
uniprot id: A0A089M2T4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

189425:PGRAT RS27815
gene id: 189425:PGRAT_RS27815
uniprot id: A0A089MBJ3
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

189425:PGRAT RS25445
gene id: 189425:PGRAT_RS25445
uniprot id: A0A089NP17
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. MTA/SAH deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L-homocysteine, respectively. Is also able to deaminate adenosine.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

189425:PGRAT RS17340
gene id: 189425:PGRAT_RS17340
uniprot id: A0A089NJW8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

189425:PGRAT RS01925
gene id: 189425:PGRAT_RS01925
uniprot id: A0A089NCA4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

189425:PGRAT RS28020
gene id: 189425:PGRAT_RS28020
uniprot id: A0A089MBN3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

189425:PGRAT RS01745
gene id: 189425:PGRAT_RS01745
uniprot id: A0A089LYC4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

189425:PGRAT RS15935
gene id: 189425:PGRAT_RS15935
uniprot id: A0A089M5L2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0053 family.
messages: Membrane

189425:PGRAT RS10095
gene id: 189425:PGRAT_RS10095
uniprot id: A0A089NG80
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

189425:PGRAT RS16540
gene id: 189425:PGRAT_RS16540
uniprot id: A0A089M7I6
names: Similarity
messages: Belongs to the peptidase C40 family.

189425:PGRAT RS20335
gene id: 189425:PGRAT_RS20335
uniprot id: A0A089MC42
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

189425:PGRAT RS19300
gene id: 189425:PGRAT_RS19300
uniprot id: A0A089M8V6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

189425:PGRAT RS00910
gene id: 189425:PGRAT_RS00910
uniprot id: A0A089LXX9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the BPG-independent phosphoglycerate mutase family.
messages: Binds 2 manganese ions per subunit.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: Monomer.

189425:PGRAT RS00915
gene id: 189425:PGRAT_RS00915
uniprot id: A0A089LZP6
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

189425:PGRAT RS23335
gene id: 189425:PGRAT_RS23335
uniprot id: A0A089MDK8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SepF family.
messages: Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA.
messages: Cytoplasm
messages: Homodimer. Interacts with FtsZ.

189425:PGRAT RS03120
gene id: 189425:PGRAT_RS03120
uniprot id: A0A089M302
names: Subcellular Location Annotation
messages: Membrane

189425:PGRAT RS05585
gene id: 189425:PGRAT_RS05585
uniprot id: A0A089M1Y0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SspH family.
messages: Spore core

189425:PGRAT RS27930
gene id: 189425:PGRAT_RS27930
uniprot id: A0A089NQ58
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

189425:PGRAT RS18855
gene id: 189425:PGRAT_RS18855
uniprot id: A0A089NKM4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family.
messages: Cell membrane
messages: Membrane

189425:PGRAT RS20445
gene id: 189425:PGRAT_RS20445
uniprot id: A0A089NLL2
names: Function
names: Similarity
messages: Belongs to the anti-sigma-factor family.
messages: Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition.

189425:PGRAT RS19865
gene id: 189425:PGRAT_RS19865
uniprot id: A0A089NL84
names: Similarity
messages: Belongs to the TrpC family.

189425:PGRAT RS00415
gene id: 189425:PGRAT_RS00415
uniprot id: A0A089NBL2
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

189425:PGRAT RS21075
gene id: 189425:PGRAT_RS21075
uniprot id: A0A089M8B3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TVP38/TMEM64 family.
messages: Cell membrane
messages: Membrane

189425:PGRAT RS07465
gene id: 189425:PGRAT_RS07465
uniprot id: A0A089M7S4
names: Similarity
messages: Belongs to the NtaA/SnaA/DszA monooxygenase family.

189425:PGRAT RS13515
gene id: 189425:PGRAT_RS13515
uniprot id: A0A089MAX0
names: Cofactor
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.
messages: Probably binds two magnesium or manganese ions per subunit.

189425:PGRAT RS12345
gene id: 189425:PGRAT_RS12345
uniprot id: A0A089M7W5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThrE exporter (TC 2.A.79) family.
messages: Membrane

189425:PGRAT RS00625
gene id: 189425:PGRAT_RS00625
uniprot id: A0A089NBQ2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

189425:PGRAT RS16235
gene id: 189425:PGRAT_RS16235
uniprot id: A0A089M9V2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. TCR/Tet family.
messages: Cell membrane
messages: Membrane

189425:PGRAT RS04340
gene id: 189425:PGRAT_RS04340
uniprot id: A0A089NDD8
names: Subcellular Location Annotation
messages: Membrane

189425:PGRAT RS04285
gene id: 189425:PGRAT_RS04285
uniprot id: A0A089NDD2
names: Subcellular Location Annotation
messages: Membrane

189425:PGRAT RS23340
gene id: 189425:PGRAT_RS23340
uniprot id: A0A089M9G5
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

189425:PGRAT RS20485
gene id: 189425:PGRAT_RS20485
uniprot id: A0A089M9L2
names: Similarity
messages: Belongs to the peptidase M20A family.

189425:PGRAT RS20590
gene id: 189425:PGRAT_RS20590
uniprot id: A0A089MES4
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

189425:PGRAT RS19875
gene id: 189425:PGRAT_RS19875
uniprot id: A0A089M7N0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate synthase component I family.
messages: Heterotetramer consisting of two non-identical subunits: a beta subunit (TrpG) and a large alpha subunit (TrpE).
messages: Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia.

189425:PGRAT RS09030
gene id: 189425:PGRAT_RS09030
uniprot id: A0A089M250
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

189425:PGRAT RS06725
gene id: 189425:PGRAT_RS06725
uniprot id: A0A089M7I3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LuxS family.
messages: Binds 1 Fe cation per subunit.
messages: Homodimer.
messages: Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD).

189425:PGRAT RS21370
gene id: 189425:PGRAT_RS21370
uniprot id: A0A089MA08
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

189425:PGRAT RS16835
gene id: 189425:PGRAT_RS16835
uniprot id: A0A089NJL4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

189425:PGRAT RS27960
gene id: 189425:PGRAT_RS27960
uniprot id: A0A089MFR7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

189425:PGRAT RS26790
gene id: 189425:PGRAT_RS26790
uniprot id: A0A089MF76
names: Similarity
messages: Belongs to the glycosyl hydrolase 18 family.

189425:PGRAT RS10865
gene id: 189425:PGRAT_RS10865
uniprot id: A0A089M313
names: Similarity
messages: Belongs to the group II decarboxylase family.

189425:PGRAT RS11455
gene id: 189425:PGRAT_RS11455
uniprot id: A0A089M4V7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

189425:PGRAT RS21940
gene id: 189425:PGRAT_RS21940
uniprot id: A0A089MCU9
names: Subcellular Location Annotation
messages: Membrane

189425:PGRAT RS00305
gene id: 189425:PGRAT_RS00305
uniprot id: A0A089LXL2
names: Function
names: Similarity
messages: Belongs to the NadC/ModD family.
messages: Involved in the catabolism of quinolinic acid (QA).

189425:PGRAT RS28985
gene id: 189425:PGRAT_RS28985
uniprot id: A0A089MDR9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

189425:PGRAT RS07625
gene id: 189425:PGRAT_RS07625
uniprot id: A0A089M1G6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

189425:PGRAT RS29765
gene id: 189425:PGRAT_RS29765
uniprot id: A0A089MCJ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0719 family.
messages: Membrane

189425:PGRAT RS00300
gene id: 189425:PGRAT_RS00300
uniprot id: A0A089M1J1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily.
messages: Catalyzes the oxidation of L-aspartate to iminoaspartate.
messages: Cytoplasm

189425:PGRAT RS15290
gene id: 189425:PGRAT_RS15290
uniprot id: A0A089NIV1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CotF family.
messages: Spore coat

189425:PGRAT RS02910
gene id: 189425:PGRAT_RS02910
uniprot id: A0A089LYX4
names: Function
names: Subunit
messages: Counteracts the endogenous Pycsar antiviral defense system. Phosphodiesterase that enables metal-dependent hydrolysis of host cyclic nucleotide Pycsar defense signals such as cCMP and cUMP.
messages: Homodimer.

189425:PGRAT RS15780
gene id: 189425:PGRAT_RS15780
uniprot id: A0A089M5I2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 5 family.
messages: Cell membrane
messages: Membrane

189425:PGRAT RS28225
gene id: 189425:PGRAT_RS28225
uniprot id: A0A089MID9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial sugar transferase family.
messages: Membrane

189425:PGRAT RS19710
gene id: 189425:PGRAT_RS19710
uniprot id: A0A089MBP2
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanD family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
messages: Cytoplasm
messages: Heterooctamer of four alpha and four beta subunits.
messages: Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus.

189425:PGRAT RS03380
gene id: 189425:PGRAT_RS03380
uniprot id: A0A089NCY2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

189425:PGRAT RS15030
gene id: 189425:PGRAT_RS15030
uniprot id: A0A089MBV0
names: Similarity
messages: Belongs to the bacterial solute-binding protein 1 family.

189425:PGRAT RS27945
gene id: 189425:PGRAT_RS27945
uniprot id: A0A089MD45
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

189425:PGRAT RS28790
gene id: 189425:PGRAT_RS28790
uniprot id: A0A089MC54
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

189425:PGRAT RS16315
gene id: 189425:PGRAT_RS16315
uniprot id: A0A089MCD0
names: Similarity
messages: Belongs to the PspA/IM30 family.

189425:PGRAT RS00185
gene id: 189425:PGRAT_RS00185
uniprot id: A0A089LZ96
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
messages: Cytoplasm
messages: Homotrimer.
messages: In the C-terminal section; belongs to the transferase hexapeptide repeat family.
messages: In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

189425:PGRAT RS09355
gene id: 189425:PGRAT_RS09355
uniprot id: A0A089M6C7
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 51 family.
messages: Homohexamer; trimer of dimers.

189425:PGRAT RS08910
gene id: 189425:PGRAT_RS08910
uniprot id: A0A089M620
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

189425:PGRAT RS31015
gene id: 189425:PGRAT_RS31015
uniprot id: A0A089MHB8
names: Similarity
messages: Belongs to the ParB family.

189425:PGRAT RS24195
gene id: 189425:PGRAT_RS24195
uniprot id: A0A089ME06
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

189425:PGRAT RS15075
gene id: 189425:PGRAT_RS15075
uniprot id: A0A089M575
names: Similarity
messages: Belongs to the GerABKA family.

189425:PGRAT RS20960
gene id: 189425:PGRAT_RS20960
uniprot id: A0A089MCC1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycyl radical enzyme (GRE) family. PFL subfamily.
messages: Catalyzes the conversion of pyruvate to formate and acetyl-CoA.
messages: Cytoplasm
messages: Homodimer.

189425:PGRAT RS28365
gene id: 189425:PGRAT_RS28365
uniprot id: A0A089MFZ4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family. C-terminal subunit subfamily.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H. In this organism, the P 'protein' is a heterodimer of two subunits.

189425:PGRAT RS02160
gene id: 189425:PGRAT_RS02160
uniprot id: A0A089M517
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

189425:PGRAT RS00475
gene id: 189425:PGRAT_RS00475
uniprot id: A0A089M1M5
names: Similarity
messages: Belongs to the MotB family.

189425:PGRAT RS00465
gene id: 189425:PGRAT_RS00465
uniprot id: A0A089M475
names: Subcellular Location Annotation
messages: Membrane

189425:PGRAT RS00345
gene id: 189425:PGRAT_RS00345
uniprot id: A0A089M448
names: Function
names: Similarity
messages: Belongs to the DHPS family.
messages: Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives.

189425:PGRAT RS07080
gene id: 189425:PGRAT_RS07080
uniprot id: A0A089M546
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-3 family.
messages: Cytoplasm
messages: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.
messages: Monomer.

189425:PGRAT RS24270
gene id: 189425:PGRAT_RS24270
uniprot id: A0A089NND1
names: Subcellular Location Annotation
messages: Membrane

189425:PGRAT RS24175
gene id: 189425:PGRAT_RS24175
uniprot id: A0A089M9V6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

189425:PGRAT RS02025
gene id: 189425:PGRAT_RS02025
uniprot id: A0A089M083
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

189425:PGRAT RS07375
gene id: 189425:PGRAT_RS07375
uniprot id: A0A089M587
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

189425:PGRAT RS25715
gene id: 189425:PGRAT_RS25715
uniprot id: A0A089MH91
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the ferredoxin--NADP reductase type 2 family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

189425:PGRAT RS15265
gene id: 189425:PGRAT_RS15265
uniprot id: A0A089NIU7
names: Subcellular Location Annotation
messages: Membrane

189425:PGRAT RS10955
gene id: 189425:PGRAT_RS10955
uniprot id: A0A089M9H1
names: Similarity
messages: Belongs to the DCK/DGK family.

189425:PGRAT RS29455
gene id: 189425:PGRAT_RS29455
uniprot id: A0A089MGJ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

189425:PGRAT RS29120
gene id: 189425:PGRAT_RS29120
uniprot id: A0A089MCA4
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 zinc ion per subunit.

189425:PGRAT RS05080
gene id: 189425:PGRAT_RS05080
uniprot id: A0A089M3Z6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Membrane

189425:PGRAT RS15795
gene id: 189425:PGRAT_RS15795
uniprot id: A0A089MC41
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M4 family.
messages: Extracellular zinc metalloprotease.
messages: Secreted

189425:PGRAT RS06675
gene id: 189425:PGRAT_RS06675
uniprot id: A0A089M7H7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

189425:PGRAT RS15490
gene id: 189425:PGRAT_RS15490
uniprot id: A0A089M717
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

189425:PGRAT RS20630
gene id: 189425:PGRAT_RS20630
uniprot id: A0A089M839
names: Subcellular Location Annotation
messages: Membrane

189425:PGRAT RS00490
gene id: 189425:PGRAT_RS00490
uniprot id: A0A089M481
names: Similarity
messages: Belongs to the pterin-4-alpha-carbinolamine dehydratase family.

189425:PGRAT RS25700
gene id: 189425:PGRAT_RS25700
uniprot id: A0A089MER4
names: Similarity
messages: Belongs to the ChdC family. Type 1 subfamily.

189425:PGRAT RS03555
gene id: 189425:PGRAT_RS03555
uniprot id: A0A089M5V0
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

189425:PGRAT RS07165
gene id: 189425:PGRAT_RS07165
uniprot id: A0A089M2U7
names: Similarity
messages: Belongs to the zinc-associated anti-sigma factor (ZAS) superfamily. Anti-sigma-W factor family.

189425:PGRAT RS20880
gene id: 189425:PGRAT_RS20880
uniprot id: A0A089NLS5
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DtxR/MntR family.
messages: Central regulator of manganese homeostasis.
messages: Cytoplasm
messages: DNA binding is strongly activated by Mn(2+).
messages: Homodimer.

189425:PGRAT RS20595
gene id: 189425:PGRAT_RS20595
uniprot id: A0A089NLN6
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LipB family.
messages: Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
messages: Cytoplasm
messages: In the reaction, the free carboxyl group of octanoic acid is attached via an amide linkage to the epsilon-amino group of a specific lysine residue of lipoyl domains of lipoate-dependent enzymes.

189425:PGRAT RS00605
gene id: 189425:PGRAT_RS00605
uniprot id: A0A089M1P9
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

189425:PGRAT RS13710
gene id: 189425:PGRAT_RS13710
uniprot id: A0A089MB06
names: Function
names: Similarity
names: Subunit
messages: Belongs to the diaminopimelate dehydrogenase family.
messages: Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L-tetrahydrodipicolinate, to generate the meso compound, D,L-2,6-diaminopimelate.
messages: Homodimer.

189425:PGRAT RS25285
gene id: 189425:PGRAT_RS25285
uniprot id: A0A089MAD9
names: Similarity
messages: Belongs to the GerABKC lipoprotein family.

189425:PGRAT RS28950
gene id: 189425:PGRAT_RS28950
uniprot id: A0A089MGD3
names: Subcellular Location Annotation
messages: Membrane

189425:PGRAT RS09000
gene id: 189425:PGRAT_RS09000
uniprot id: A0A089M637
names: Function
names: Similarity
messages: Belongs to the N-acylglucosamine 2-epimerase family.
messages: Belongs to the cellobiose 2-epimerase family.
messages: Catalyzes the reversible epimerization of cellobiose to 4-O-beta-D-glucopyranosyl-D-mannose (Glc-Man).

189425:PGRAT RS09165
gene id: 189425:PGRAT_RS09165
uniprot id: A0A089M278
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).

189425:PGRAT RS12650
gene id: 189425:PGRAT_RS12650
uniprot id: A0A089M5I9
names: Subcellular Location Annotation
messages: Membrane

189425:PGRAT RS17050
gene id: 189425:PGRAT_RS17050
uniprot id: A0A089NJQ9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the rhamnose isomerase family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the interconversion of L-rhamnose and L-rhamnulose.
messages: Cytoplasm

189425:PGRAT RS11730
gene id: 189425:PGRAT_RS11730
uniprot id: A0A089NH14
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

189425:PGRAT RS01495
gene id: 189425:PGRAT_RS01495
uniprot id: A0A089M014
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M20 family.
messages: Binds 2 Zn(2+) ions per subunit.

189425:PGRAT RS14345
gene id: 189425:PGRAT_RS14345
uniprot id: A0A089MBE9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

189425:PGRAT RS26480
gene id: 189425:PGRAT_RS26480
uniprot id: A0A089MF38
names: Similarity
messages: Belongs to the radical SAM superfamily. Anaerobic sulfatase-maturating enzyme family.

189425:PGRAT RS09710
gene id: 189425:PGRAT_RS09710
uniprot id: A0A089M2I6
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

189425:PGRAT RS27990
gene id: 189425:PGRAT_RS27990
uniprot id: A0A089MFS3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

189425:PGRAT RS26515
gene id: 189425:PGRAT_RS26515
uniprot id: A0A089MCI9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

189425:PGRAT RS14645
gene id: 189425:PGRAT_RS14645
uniprot id: A0A089MBL5
names: Similarity
messages: Belongs to the AHA1 family.

189425:PGRAT RS27440
gene id: 189425:PGRAT_RS27440
uniprot id: A0A089MHZ3
names: Subcellular Location Annotation
messages: Membrane

189425:PGRAT RS22710
gene id: 189425:PGRAT_RS22710
uniprot id: A0A089M949
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the arabinose isomerase family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the conversion of L-arabinose to L-ribulose.

189425:PGRAT RS11715
gene id: 189425:PGRAT_RS11715
uniprot id: A0A089M3E9
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

189425:PGRAT RS21000
gene id: 189425:PGRAT_RS21000
uniprot id: A0A089MEY0
names: Cofactor
messages: Binds 2 magnesium ions per subunit.

189425:PGRAT RS27900
gene id: 189425:PGRAT_RS27900
uniprot id: A0A089MI70
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

189425:PGRAT RS28725
gene id: 189425:PGRAT_RS28725
uniprot id: A0A089MIP3
names: Similarity
messages: Belongs to the flagella basal body rod proteins family.

189425:PGRAT RS19645
gene id: 189425:PGRAT_RS19645
uniprot id: A0A089M927
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

189425:PGRAT RS19465
gene id: 189425:PGRAT_RS19465
uniprot id: A0A089M8Z1
names: Subcellular Location Annotation
messages: Membrane

189425:PGRAT RS16920
gene id: 189425:PGRAT_RS16920
uniprot id: A0A089M636
names: Subcellular Location Annotation
messages: Membrane

189425:PGRAT RS14060
gene id: 189425:PGRAT_RS14060
uniprot id: A0A089MB77
names: Subcellular Location Annotation
messages: Membrane

189425:PGRAT RS00595
gene id: 189425:PGRAT_RS00595
uniprot id: A0A089M4A3
names: Cofactor
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.

189425:PGRAT RS23345
gene id: 189425:PGRAT_RS23345
uniprot id: A0A089MAY9
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

189425:PGRAT RS21330
gene id: 189425:PGRAT_RS21330
uniprot id: A0A089MCJ2
names: Function
names: Similarity
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
messages: In the C-terminal section; belongs to the NAD synthetase family.

189425:PGRAT RS13210
gene id: 189425:PGRAT_RS13210
uniprot id: A0A089M470
names: Subcellular Location Annotation
messages: Membrane

189425:PGRAT RS04635
gene id: 189425:PGRAT_RS04635
uniprot id: A0A089LZT9
names: Similarity
messages: Belongs to the catalase family.

189425:PGRAT RS29565
gene id: 189425:PGRAT_RS29565
uniprot id: A0A089MJ31
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

189425:PGRAT RS07335
gene id: 189425:PGRAT_RS07335
uniprot id: A0A089M7Q9
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

189425:PGRAT RS22715
gene id: 189425:PGRAT_RS22715
uniprot id: A0A089MAL8
names: Cofactor
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.

189425:PGRAT RS00740
gene id: 189425:PGRAT_RS00740
uniprot id: A0A089M4B8
names: Similarity
messages: Belongs to the acyltransferase 3 family.

189425:PGRAT RS28095
gene id: 189425:PGRAT_RS28095
uniprot id: A0A089MBP9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IspF family.
messages: Binds 1 divalent metal cation per subunit.
messages: Homotrimer.
messages: Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).

189425:PGRAT RS17460
gene id: 189425:PGRAT_RS17460
uniprot id: A0A089MD20
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily.
messages: Binds 2 Zn(2+) ions per subunit. It is not clear if Zn(2+) or Mg(2+) is physiologically important.
messages: Counteracts the endogenous Pycsar antiviral defense system. Phosphodiesterase that enables metal-dependent hydrolysis of host cyclic nucleotide Pycsar defense signals such as cCMP and cUMP.
messages: Cytoplasm
messages: Homodimer, may be a subunit of the RNA degradosome.

189425:PGRAT RS22020
gene id: 189425:PGRAT_RS22020
uniprot id: A0A089MFF3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

189425:PGRAT RS01145
gene id: 189425:PGRAT_RS01145
uniprot id: A0A089NBY8
names: Subcellular Location Annotation
messages: Membrane

189425:PGRAT RS15625
gene id: 189425:PGRAT_RS15625
uniprot id: A0A089M5F4
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

189425:PGRAT RS24365
gene id: 189425:PGRAT_RS24365
uniprot id: A0A089MBF7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IA subfamily.
messages: Cell membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system and for the release of the potassium ions to the cytoplasm.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

189425:PGRAT RS05655
gene id: 189425:PGRAT_RS05655
uniprot id: A0A089M0C2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

189425:PGRAT RS19850
gene id: 189425:PGRAT_RS19850
uniprot id: A0A089M7M5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

189425:PGRAT RS19985
gene id: 189425:PGRAT_RS19985
uniprot id: A0A089MEE0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsY family.
messages: Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
messages: Cell membrane
messages: Probably interacts with PlsX.

189425:PGRAT RS20570
gene id: 189425:PGRAT_RS20570
uniprot id: A0A089NLN2
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.

189425:PGRAT RS16095
gene id: 189425:PGRAT_RS16095
uniprot id: A0A089M7B6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

189425:PGRAT RS15980
gene id: 189425:PGRAT_RS15980
uniprot id: A0A089M9Q2
names: Function
names: Subunit
messages: Counteracts the endogenous Pycsar antiviral defense system. Phosphodiesterase that enables metal-dependent hydrolysis of host cyclic nucleotide Pycsar defense signals such as cCMP and cUMP.
messages: Homodimer.

189425:PGRAT RS24360
gene id: 189425:PGRAT_RS24360
uniprot id: A0A089M9Z2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KdpC family.
messages: Cell membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

189425:PGRAT RS21855
gene id: 189425:PGRAT_RS21855
uniprot id: A0A089MCT3
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

189425:PGRAT RS19885
gene id: 189425:PGRAT_RS19885
uniprot id: A0A089MEB9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
messages: Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).
messages: Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

189425:PGRAT RS20180
gene id: 189425:PGRAT_RS20180
uniprot id: A0A089M7U0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ScpA family.
messages: Component of a cohesin-like complex composed of ScpA, ScpB and the Smc homodimer, in which ScpA and ScpB bind to the head domain of Smc. The presence of the three proteins is required for the association of the complex with DNA.
messages: Cytoplasm
messages: Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves.

189425:PGRAT RS20730
gene id: 189425:PGRAT_RS20730
uniprot id: A0A089MC87
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

189425:PGRAT RS27350
gene id: 189425:PGRAT_RS27350
uniprot id: A0A089MCV0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

189425:PGRAT RS12845
gene id: 189425:PGRAT_RS12845
uniprot id: A0A089NHH8
names: Similarity
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Spore germination protein (SGP) (TC 2.A.3.9) family.

189425:PGRAT RS10385
gene id: 189425:PGRAT_RS10385
uniprot id: A0A089M990
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
messages: Single-chain monomer with multiple functions.

189425:PGRAT RS26540
gene id: 189425:PGRAT_RS26540
uniprot id: A0A089MB07
names: Subcellular Location Annotation
messages: Membrane

189425:PGRAT RS28465
gene id: 189425:PGRAT_RS28465
uniprot id: A0A089NQH7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm
messages: Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline.

189425:PGRAT RS08645
gene id: 189425:PGRAT_RS08645
uniprot id: A0A089NFI8
names: Subcellular Location Annotation
messages: Membrane

189425:PGRAT RS08480
gene id: 189425:PGRAT_RS08480
uniprot id: A0A089M1T4
names: Similarity
messages: Belongs to the mannitol dehydrogenase family.

189425:PGRAT RS28685
gene id: 189425:PGRAT_RS28685
uniprot id: A0A089MC17
names: Subcellular Location Annotation
messages: Membrane

189425:PGRAT RS25840
gene id: 189425:PGRAT_RS25840
uniprot id: A0A089MHD6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

189425:PGRAT RS14885
gene id: 189425:PGRAT_RS14885
uniprot id: A0A089M6S4
names: Subunit
messages: Homodimer.

189425:PGRAT RS19270
gene id: 189425:PGRAT_RS19270
uniprot id: A0A089MDY1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. EmrB family.
messages: Cell membrane
messages: Membrane

189425:PGRAT RS25820
gene id: 189425:PGRAT_RS25820
uniprot id: A0A089NPB3
names: Similarity
messages: Belongs to the transpeptidase family.

189425:PGRAT RS16445
gene id: 189425:PGRAT_RS16445
uniprot id: A0A089NJD4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

189425:PGRAT RS04270
gene id: 189425:PGRAT_RS04270
uniprot id: A0A089LZP4
names: Subcellular Location Annotation
messages: Membrane

189425:PGRAT RS18005
gene id: 189425:PGRAT_RS18005
uniprot id: A0A089NKB4
names: Subcellular Location Annotation
messages: Membrane

189425:PGRAT RS16440
gene id: 189425:PGRAT_RS16440
uniprot id: A0A089MCG0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.
messages: Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.
messages: Cytoplasm
messages: Homodimer.

189425:PGRAT RS05125
gene id: 189425:PGRAT_RS05125
uniprot id: A0A089NDQ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. EmrB family.
messages: Cell membrane
messages: Membrane

189425:PGRAT RS26240
gene id: 189425:PGRAT_RS26240
uniprot id: A0A089MF01
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

189425:PGRAT RS13630
gene id: 189425:PGRAT_RS13630
uniprot id: A0A089M4E7
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

189425:PGRAT RS24065
gene id: 189425:PGRAT_RS24065
uniprot id: A0A089MDY2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

189425:PGRAT RS07085
gene id: 189425:PGRAT_RS07085
uniprot id: A0A089M173
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

189425:PGRAT RS25195
gene id: 189425:PGRAT_RS25195
uniprot id: B9X243
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NifD/NifK/NifE/NifN family.
messages: Tetramer of two alpha and two beta chains. Forms complex with the iron protein (nitrogenase component 2).
messages: This molybdenum-iron protein is part of the nitrogenase complex that catalyzes the key enzymatic reactions in nitrogen fixation.

189425:PGRAT RS04645
gene id: 189425:PGRAT_RS04645
uniprot id: A0A089M1I8
names: Function
names: Similarity
messages: Belongs to the glycogen phosphorylase family.
messages: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.

189425:PGRAT RS26300
gene id: 189425:PGRAT_RS26300
uniprot id: A0A089MF08
names: Subcellular Location Annotation
messages: Membrane

189425:PGRAT RS05430
gene id: 189425:PGRAT_RS05430
uniprot id: A0A089M1V7
names: Similarity
messages: Belongs to the ABC transporter superfamily.

189425:PGRAT RS28595
gene id: 189425:PGRAT_RS28595
uniprot id: A0A089MIL6
names: Similarity
messages: Belongs to the bacterial flagellin family.

189425:PGRAT RS01715
gene id: 189425:PGRAT_RS01715
uniprot id: A0A089M045
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.

189425:PGRAT RS15965
gene id: 189425:PGRAT_RS15965
uniprot id: A0A089M793
names: Similarity
messages: Belongs to the peptidase M29 family.

189425:PGRAT RS15495
gene id: 189425:PGRAT_RS15495
uniprot id: A0A089MC08
names: Subcellular Location Annotation
messages: cytosol

189425:PGRAT RS20075
gene id: 189425:PGRAT_RS20075
uniprot id: A0A089MBW7
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

189425:PGRAT RS13400
gene id: 189425:PGRAT_RS13400
uniprot id: A0A089M5W2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. EmrB family.
messages: Cell membrane
messages: Membrane

189425:PGRAT RS17470
gene id: 189425:PGRAT_RS17470
uniprot id: A0A089MAI4
names: Function
names: Similarity
messages: Belongs to the aspartokinase family.
messages: Catalyzes the phosphorylation of the beta-carboxyl group of aspartic acid with ATP to yield 4-phospho-L-aspartate, which is involved in the branched biosynthetic pathway leading to the biosynthesis of amino acids threonine, isoleucine and methionine.

189425:PGRAT RS28080
gene id: 189425:PGRAT_RS28080
uniprot id: A0A089MIB0
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

189425:PGRAT RS17780
gene id: 189425:PGRAT_RS17780
uniprot id: A0A089M6N0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

189425:PGRAT RS19860
gene id: 189425:PGRAT_RS19860
uniprot id: A0A089MEB3
names: Similarity
messages: Belongs to the TrpF family.

189425:PGRAT RS04425
gene id: 189425:PGRAT_RS04425
uniprot id: A0A089LZR7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

189425:PGRAT RS02425
gene id: 189425:PGRAT_RS02425
uniprot id: A0A089NCI3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic sulfate-binding protein family.
messages: Periplasm

189425:PGRAT RS28705
gene id: 189425:PGRAT_RS28705
uniprot id: A0A089MG74
names: Similarity
messages: Belongs to the phosphohexose mutase family.

189425:PGRAT RS16385
gene id: 189425:PGRAT_RS16385
uniprot id: A0A089M7F6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
messages: Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.
messages: Monomer.

189425:PGRAT RS19425
gene id: 189425:PGRAT_RS19425
uniprot id: A0A089NKZ2
names: Function
names: Similarity
messages: Belongs to the flavodoxin family.
messages: Low-potential electron donor to a number of redox enzymes.

189425:PGRAT RS27220
gene id: 189425:PGRAT_RS27220
uniprot id: A0A089MHV3
names: Subcellular Location Annotation
messages: Membrane

189425:PGRAT RS28565
gene id: 189425:PGRAT_RS28565
uniprot id: A0A089MDG3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliS family.
messages: cytosol

189425:PGRAT RS06185
gene id: 189425:PGRAT_RS06185
uniprot id: A0A089M4M1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

189425:PGRAT RS14750
gene id: 189425:PGRAT_RS14750
uniprot id: A0A089MBN7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

189425:PGRAT RS27460
gene id: 189425:PGRAT_RS27460
uniprot id: A0A089MBE4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Amj family.
messages: Cell membrane
messages: Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.

189425:PGRAT RS09980
gene id: 189425:PGRAT_RS09980
uniprot id: A0A089M2M5
names: Similarity
messages: Belongs to the CapA family.

189425:PGRAT RS12925
gene id: 189425:PGRAT_RS12925
uniprot id: A0A089NHI9
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

189425:PGRAT RS12310
gene id: 189425:PGRAT_RS12310
uniprot id: A0A089MAE1
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

189425:PGRAT RS05775
gene id: 189425:PGRAT_RS05775
uniprot id: A0A089NE32
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reduced FMN (FMNH(2)).

189425:PGRAT RS16460
gene id: 189425:PGRAT_RS16460
uniprot id: A0A089M7H1
names: Similarity
messages: Belongs to the GerABKA family.

189425:PGRAT RS19950
gene id: 189425:PGRAT_RS19950
uniprot id: A0A089M7P7
names: Function
names: Subcellular Location Annotation
messages: ATPase. Has a role at an early stage in the morphogenesis of the spore coat.
messages: Cytoplasm

189425:PGRAT RS09470
gene id: 189425:PGRAT_RS09470
uniprot id: A0A089M2F5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the radical SAM superfamily. MqnC family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2).

189425:PGRAT RS08115
gene id: 189425:PGRAT_RS08115
uniprot id: A0A089M386
names: Subcellular Location Annotation
messages: Membrane

189425:PGRAT RS11095
gene id: 189425:PGRAT_RS11095
uniprot id: A0A089M9J4
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily.

189425:PGRAT RS27245
gene id: 189425:PGRAT_RS27245
uniprot id: A0A089MCT1
names: Similarity
messages: Belongs to the glutathione peroxidase family.

189425:PGRAT RS16530
gene id: 189425:PGRAT_RS16530
uniprot id: A0A089MA10
names: Similarity
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.

189425:PGRAT RS15345
gene id: 189425:PGRAT_RS15345
uniprot id: A0A089NIV9
names: Subcellular Location Annotation
messages: Membrane

189425:PGRAT RS28820
gene id: 189425:PGRAT_RS28820
uniprot id: A0A089MDN6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

189425:PGRAT RS07325
gene id: 189425:PGRAT_RS07325
uniprot id: A0A089M1B4
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. Allantoinase family.
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Carboxylation allows a single lysine to coordinate two zinc ions.
messages: Catalyzes the conversion of allantoin (5-ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
messages: Homotetramer.

189425:PGRAT RS28240
gene id: 189425:PGRAT_RS28240
uniprot id: A0A089MBR9
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

189425:PGRAT RS10390
gene id: 189425:PGRAT_RS10390
uniprot id: A0A089NGD4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FPG family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
messages: Monomer.

189425:PGRAT RS29320
gene id: 189425:PGRAT_RS29320
uniprot id: A0A089MGH4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aldehyde dehydrogenase family. IolA subfamily.
messages: Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively.
messages: Homotetramer.

189425:PGRAT RS25180
gene id: 189425:PGRAT_RS25180
uniprot id: A0A089MEG7
names: Function
names: Similarity
messages: Belongs to the NifD/NifK/NifE/NifN family.
messages: This protein may play a role in the biosynthesis of the prosthetic group of nitrogenase (FeMo cofactor).

189425:PGRAT RS07185
gene id: 189425:PGRAT_RS07185
uniprot id: A0A089M560
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.

189425:PGRAT RS21890
gene id: 189425:PGRAT_RS21890
uniprot id: A0A089M8R0
names: Subcellular Location Annotation
messages: Membrane

189425:PGRAT RS21395
gene id: 189425:PGRAT_RS21395
uniprot id: A0A089MA13
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

189425:PGRAT RS00620
gene id: 189425:PGRAT_RS00620
uniprot id: A0A089M4A8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

189425:PGRAT RS00190
gene id: 189425:PGRAT_RS00190
uniprot id: A0A089M415
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

189425:PGRAT RS04325
gene id: 189425:PGRAT_RS04325
uniprot id: A0A089LZQ1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 6-phosphogluconate dehydrogenase family.
messages: Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
messages: Homodimer.

189425:PGRAT RS17725
gene id: 189425:PGRAT_RS17725
uniprot id: A0A089M6M3
names: Similarity
messages: Belongs to the flagella basal body rod proteins family.

189425:PGRAT RS23620
gene id: 189425:PGRAT_RS23620
uniprot id: A0A089MB31
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

189425:PGRAT RS31020
gene id: 189425:PGRAT_RS31020
uniprot id: A0A089MD76
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the N7 position of guanine in position 535 of 16S rRNA.

189425:PGRAT RS13970
gene id: 189425:PGRAT_RS13970
uniprot id: A0A089M8N2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

189425:PGRAT RS21155
gene id: 189425:PGRAT_RS21155
uniprot id: A0A089M8C8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

189425:PGRAT RS10500
gene id: 189425:PGRAT_RS10500
uniprot id: A0A089NGF5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

189425:PGRAT RS13080
gene id: 189425:PGRAT_RS13080
uniprot id: A0A089MAP9
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

189425:PGRAT RS14285
gene id: 189425:PGRAT_RS14285
uniprot id: A0A089M6B6
names: Similarity
messages: Belongs to the glycosyl hydrolase 42 family.

189425:PGRAT RS11820
gene id: 189425:PGRAT_RS11820
uniprot id: A0A089NH29
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit C family.
messages: Membrane

189425:PGRAT RS18000
gene id: 189425:PGRAT_RS18000
uniprot id: A0A089MDD9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

189425:PGRAT RS28385
gene id: 189425:PGRAT_RS28385
uniprot id: A0A089NQG0
names: Subcellular Location Annotation
messages: Membrane

189425:PGRAT RS11150
gene id: 189425:PGRAT_RS11150
uniprot id: A0A089NGR8
names: Similarity
messages: Belongs to the HepT RNase toxin family.

189425:PGRAT RS30840
gene id: 189425:PGRAT_RS30840
uniprot id: A0A089MD46
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Cell membrane
messages: Membrane

189425:PGRAT RS16800
gene id: 189425:PGRAT_RS16800
uniprot id: A0A089MCM9
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.
messages: This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.

189425:PGRAT RS02110
gene id: 189425:PGRAT_RS02110
uniprot id: A0A089NCD2
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit A family.

189425:PGRAT RS27395
gene id: 189425:PGRAT_RS27395
uniprot id: A0A089MBD3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family. Thioredoxin-coupled ArsC subfamily.
messages: Catalyzes the reduction of arsenate [As(V)] to arsenite [As(III)].
messages: Cytoplasm

189425:PGRAT RS05945
gene id: 189425:PGRAT_RS05945
uniprot id: A0A089M251
names: Similarity
messages: Belongs to the GerABKC lipoprotein family.

189425:PGRAT RS13495
gene id: 189425:PGRAT_RS13495
uniprot id: A0A089NHV1
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

189425:PGRAT RS08355
gene id: 189425:PGRAT_RS08355
uniprot id: A0A089M851
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

189425:PGRAT RS25890
gene id: 189425:PGRAT_RS25890
uniprot id: A0A089MHF5
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

189425:PGRAT RS20130
gene id: 189425:PGRAT_RS20130
uniprot id: A0A089M7T0
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

189425:PGRAT RS08595
gene id: 189425:PGRAT_RS08595
uniprot id: A0A089NFH7
names: Similarity
messages: Belongs to the CvfB family.

189425:PGRAT RS14150
gene id: 189425:PGRAT_RS14150
uniprot id: A0A089M4P3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. EmrB family.
messages: Cell membrane
messages: Membrane

189425:PGRAT RS28570
gene id: 189425:PGRAT_RS28570
uniprot id: A0A089MIL1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum
messages: Belongs to the FliD family.
messages: Homopentamer.
messages: Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.
messages: Secreted

189425:PGRAT RS15295
gene id: 189425:PGRAT_RS15295
uniprot id: A0A089M9E6
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

189425:PGRAT RS22865
gene id: 189425:PGRAT_RS22865
uniprot id: A0A089MDB1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacteriophage holin family. Cp-1 holin subfamily.
messages: Membrane

189425:PGRAT RS20295
gene id: 189425:PGRAT_RS20295
uniprot id: A0A089M9I6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

189425:PGRAT RS22460
gene id: 189425:PGRAT_RS22460
uniprot id: A0A089NMK5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the xylose isomerase family.
messages: Cytoplasm
messages: Homotetramer.

189425:PGRAT RS20845
gene id: 189425:PGRAT_RS20845
uniprot id: A0A089M9R8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

189425:PGRAT RS11460
gene id: 189425:PGRAT_RS11460
uniprot id: A0A089M9S1
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

189425:PGRAT RS25190
gene id: 189425:PGRAT_RS25190
uniprot id: A0A089MBT8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NifD/NifK/NifE/NifN family.
messages: Binds 1 [8Fe-7S] cluster per heterodimer.
messages: Tetramer of two alpha and two beta chains. Forms complex with the iron protein (nitrogenase component 2).
messages: This molybdenum-iron protein is part of the nitrogenase complex that catalyzes the key enzymatic reactions in nitrogen fixation.

189425:PGRAT RS12570
gene id: 189425:PGRAT_RS12570
uniprot id: A0A089M3W0
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-I family.

189425:PGRAT RS08775
gene id: 189425:PGRAT_RS08775
uniprot id: A0A089M8F0
names: Subcellular Location Annotation
messages: Membrane

189425:PGRAT RS25030
gene id: 189425:PGRAT_RS25030
uniprot id: A0A089MEE3
names: Subcellular Location Annotation
messages: Membrane

189425:PGRAT RS21235
gene id: 189425:PGRAT_RS21235
uniprot id: A0A089M9Y5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase H family.
messages: Binds 2 metal ions per subunit. Manganese or magnesium.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.

189425:PGRAT RS10170
gene id: 189425:PGRAT_RS10170
uniprot id: A0A089M4B7
names: Similarity
messages: Belongs to the GerABKA family.

189425:PGRAT RS24595
gene id: 189425:PGRAT_RS24595
uniprot id: A0A089ME56
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

189425:PGRAT RS05505
gene id: 189425:PGRAT_RS05505
uniprot id: A0A089M089
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

189425:PGRAT RS29460
gene id: 189425:PGRAT_RS29460
uniprot id: A0A089MCF4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

189425:PGRAT RS29060
gene id: 189425:PGRAT_RS29060
uniprot id: A0A089MC97
names: Similarity
messages: Belongs to the glutathione peroxidase family.

189425:PGRAT RS24190
gene id: 189425:PGRAT_RS24190
uniprot id: A0A089NNB7
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

189425:PGRAT RS02565
gene id: 189425:PGRAT_RS02565
uniprot id: A0A089M2P5
names: Subcellular Location Annotation
messages: Membrane

189425:PGRAT RS00010
gene id: 189425:PGRAT_RS00010
uniprot id: A0A089LXF0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

189425:PGRAT RS27340
gene id: 189425:PGRAT_RS27340
uniprot id: A0A089MFH2
names: Subcellular Location Annotation
messages: Membrane

189425:PGRAT RS09640
gene id: 189425:PGRAT_RS09640
uniprot id: A0A089M8Z2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

189425:PGRAT RS14230
gene id: 189425:PGRAT_RS14230
uniprot id: A0A089M4Q9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0702 family.
messages: Cell membrane
messages: Membrane

189425:PGRAT RS13365
gene id: 189425:PGRAT_RS13365
uniprot id: A0A089M499
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).

189425:PGRAT RS00290
gene id: 189425:PGRAT_RS00290
uniprot id: A0A089M437
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

189425:PGRAT RS09300
gene id: 189425:PGRAT_RS09300
uniprot id: A0A089M3U9
names: Similarity
messages: Belongs to the Cob(I)alamin adenosyltransferase family.

189425:PGRAT RS12680
gene id: 189425:PGRAT_RS12680
uniprot id: A0A089MAJ9
names: Function
messages: Global transcriptional regulator of carbon catabolite repression (CCR) and carbon catabolite activation (CCA), which ensures optimal energy usage under diverse conditions.

189425:PGRAT RS07945
gene id: 189425:PGRAT_RS07945
uniprot id: A0A089M360
names: Similarity
messages: Belongs to the glycosyl hydrolase 26 family.

189425:PGRAT RS06430
gene id: 189425:PGRAT_RS06430
uniprot id: A0A089M2E2
names: Similarity
messages: Belongs to the leucine-binding protein family.

189425:PGRAT RS19495
gene id: 189425:PGRAT_RS19495
uniprot id: A0A089ME24
names: Subcellular Location Annotation
messages: Membrane

189425:PGRAT RS23380
gene id: 189425:PGRAT_RS23380
uniprot id: A0A089NN03
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.
messages: Cell membrane
messages: Self-interacts. Interacts with FtsZ.

189425:PGRAT RS07205
gene id: 189425:PGRAT_RS07205
uniprot id: A0A089NES9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M17 family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm
messages: Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.

189425:PGRAT RS06845
gene id: 189425:PGRAT_RS06845
uniprot id: A0A089M2P0
names: Function
names: Similarity
messages: Belongs to the CobT family.
messages: Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB).

189425:PGRAT RS17675
gene id: 189425:PGRAT_RS17675
uniprot id: A0A089M6L6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type III secretion exporter family.
messages: Cell membrane
messages: Membrane
messages: Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

189425:PGRAT RS26405
gene id: 189425:PGRAT_RS26405
uniprot id: A0A089MF30
names: Similarity
messages: Belongs to the glycosyl hydrolase 36 family.

189425:PGRAT RS09495
gene id: 189425:PGRAT_RS09495
uniprot id: A0A089M2F8
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

189425:PGRAT RS03410
gene id: 189425:PGRAT_RS03410
uniprot id: A0A089NCY8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. EmrB family.
messages: Cell membrane
messages: Membrane

189425:PGRAT RS19960
gene id: 189425:PGRAT_RS19960
uniprot id: A0A089MED4
names: Similarity
messages: Belongs to the adrenodoxin/putidaredoxin family.

189425:PGRAT RS29145
gene id: 189425:PGRAT_RS29145
uniprot id: A0A089MCA8
names: Subcellular Location Annotation
messages: Membrane

189425:PGRAT RS26865
gene id: 189425:PGRAT_RS26865
uniprot id: A0A089MF91
names: Function
names: Subunit
messages: Counteracts the endogenous Pycsar antiviral defense system. Phosphodiesterase that enables metal-dependent hydrolysis of host cyclic nucleotide Pycsar defense signals such as cCMP and cUMP.
messages: Homodimer.

189425:PGRAT RS02280
gene id: 189425:PGRAT_RS02280
uniprot id: A0A089M0C6
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

189425:PGRAT RS07100
gene id: 189425:PGRAT_RS07100
uniprot id: A0A089NER2
names: Similarity
messages: Belongs to the BMP lipoprotein family.

189425:PGRAT RS25750
gene id: 189425:PGRAT_RS25750
uniprot id: A0A089MES6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the radical SAM superfamily. MqnE family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3-[(1-carboxyvinyl)oxy]benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate.

189425:PGRAT RS10760
gene id: 189425:PGRAT_RS10760
uniprot id: A0A089NGK0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

189425:PGRAT RS17360
gene id: 189425:PGRAT_RS17360
uniprot id: A0A089MCZ9
names: Function
names: Similarity
messages: Belongs to the PduL family.
messages: Involved in 1,2-propanediol (1,2-PD) degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate.

189425:PGRAT RS20280
gene id: 189425:PGRAT_RS20280
uniprot id: A0A089NLI5
names: Similarity
messages: Belongs to the EamA transporter family.

189425:PGRAT RS12985
gene id: 189425:PGRAT_RS12985
uniprot id: A0A089M850
names: Subcellular Location Annotation
messages: Membrane

189425:PGRAT RS17290
gene id: 189425:PGRAT_RS17290
uniprot id: A0A089NJV9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

189425:PGRAT RS20005
gene id: 189425:PGRAT_RS20005
uniprot id: A0A089M997
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

189425:PGRAT RS21975
gene id: 189425:PGRAT_RS21975
uniprot id: A0A089M8S1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

189425:PGRAT RS28830
gene id: 189425:PGRAT_RS28830
uniprot id: A0A089NQR1
names: Similarity
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.

189425:PGRAT RS30140
gene id: 189425:PGRAT_RS30140
uniprot id: A0A089ME90
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. NasA/NapA/NarB subfamily.

189425:PGRAT RS22505
gene id: 189425:PGRAT_RS22505
uniprot id: A0A089M912
names: Subcellular Location Annotation
messages: Membrane

189425:PGRAT RS08145
gene id: 189425:PGRAT_RS08145
uniprot id: A0A089M821
names: Similarity
messages: Belongs to the glycosyl hydrolase 32 family.

189425:PGRAT RS19745
gene id: 189425:PGRAT_RS19745
uniprot id: A0A089M7K1
names: Function
names: Similarity
messages: Belongs to the methylglyoxal synthase family.
messages: Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate.

189425:PGRAT RS05305
gene id: 189425:PGRAT_RS05305
uniprot id: A0A089M6L1
names: Subcellular Location Annotation
messages: Membrane

189425:PGRAT RS27530
gene id: 189425:PGRAT_RS27530
uniprot id: A0A089MI08
names: Similarity
messages: Belongs to the zinc-associated anti-sigma factor (ZAS) superfamily. Anti-sigma-W factor family.

189425:PGRAT RS28775
gene id: 189425:PGRAT_RS28775
uniprot id: A0A089MIQ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

189425:PGRAT RS17995
gene id: 189425:PGRAT_RS17995
uniprot id: A0A089M8A8
names: Similarity
messages: Belongs to the asp23 family.

189425:PGRAT RS03730
gene id: 189425:PGRAT_RS03730
uniprot id: A0A089M149
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

189425:PGRAT RS14185
gene id: 189425:PGRAT_RS14185
uniprot id: A0A089MBB1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

189425:PGRAT RS13125
gene id: 189425:PGRAT_RS13125
uniprot id: A0A089M872
names: Similarity
messages: Belongs to the cycloisomerase 2 family.

189425:PGRAT RS17950
gene id: 189425:PGRAT_RS17950
uniprot id: A0A089MDD2
names: Function
names: Similarity
messages: Belongs to the UPF0122 family.
messages: Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY/ffh. May be a regulatory protein.

189425:PGRAT RS00405
gene id: 189425:PGRAT_RS00405
uniprot id: A0A089LZD8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PdxS/SNZ family.
messages: Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively.
messages: In the presence of PdxT, forms a dodecamer of heterodimers.

189425:PGRAT RS10510
gene id: 189425:PGRAT_RS10510
uniprot id: A0A089M2V3
names: Similarity
messages: Belongs to the class I fructose-bisphosphate aldolase family.

189425:PGRAT RS05230
gene id: 189425:PGRAT_RS05230
uniprot id: A0A089NDS8
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

189425:PGRAT RS08495
gene id: 189425:PGRAT_RS08495
uniprot id: A0A089NFF8
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

189425:PGRAT RS23115
gene id: 189425:PGRAT_RS23115
uniprot id: A0A089NMX7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

189425:PGRAT RS17305
gene id: 189425:PGRAT_RS17305
uniprot id: A0A089M7X3
names: Subcellular Location Annotation
messages: Membrane

189425:PGRAT RS06090
gene id: 189425:PGRAT_RS06090
uniprot id: A0A089M4K3
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

189425:PGRAT RS21845
gene id: 189425:PGRAT_RS21845
uniprot id: A0A089MFC3
names: Similarity
messages: Belongs to the sigma-54 factor family.

189425:PGRAT RS05235
gene id: 189425:PGRAT_RS05235
uniprot id: A0A089M427
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

189425:PGRAT RS10020
gene id: 189425:PGRAT_RS10020
uniprot id: A0A089M945
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

189425:PGRAT RS05735
gene id: 189425:PGRAT_RS05735
uniprot id: A0A089M206
names: Similarity
messages: Belongs to the UPF0047 family.

189425:PGRAT RS07445
gene id: 189425:PGRAT_RS07445
uniprot id: A0A089NEX1
names: Similarity
messages: To bacterial alkanal monooxygenase alpha and beta chains.

189425:PGRAT RS07330
gene id: 189425:PGRAT_RS07330
uniprot id: A0A089M2X4
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M20 family.
messages: Binds 2 Zn(2+) ions per subunit.

189425:PGRAT RS18280
gene id: 189425:PGRAT_RS18280
uniprot id: A0A089MDG9
names: Similarity
messages: Belongs to the HicA mRNA interferase family.

189425:PGRAT RS27870
gene id: 189425:PGRAT_RS27870
uniprot id: A0A089MD32
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

189425:PGRAT RS12735
gene id: 189425:PGRAT_RS12735
uniprot id: A0A089NHG4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family.
messages: Ca(+)/H(+) antiporter that extrudes calcium in exchange for external protons.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

189425:PGRAT RS04705
gene id: 189425:PGRAT_RS04705
uniprot id: A0A089NDI3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

189425:PGRAT RS28965
gene id: 189425:PGRAT_RS28965
uniprot id: A0A089MIW0
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MobA family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The N-terminal domain determines nucleotide recognition and specific binding, while the C-terminal domain determines the specific binding to the target protein.
messages: Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor.

189425:PGRAT RS30915
gene id: 189425:PGRAT_RS30915
uniprot id: A0A089MD60
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GdpP/PdeA phosphodiesterase family.
messages: Cell membrane
messages: For phosphodiesterase activity, probably binds 2 Mn(2+) per subunit.
messages: Has phosphodiesterase (PDE) activity against cyclic-di-AMP (c-di-AMP).

189425:PGRAT RS27135
gene id: 189425:PGRAT_RS27135
uniprot id: A0A089MCR3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

189425:PGRAT RS16520
gene id: 189425:PGRAT_RS16520
uniprot id: A0A089MCH6
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta chain.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).

189425:PGRAT RS08995
gene id: 189425:PGRAT_RS08995
uniprot id: A0A089NFP8
names: Function
names: Similarity
messages: Belongs to the glycosyl hydrolase 130 family.
messages: Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man-Glc) to mannose 1-phosphate (Man1P) and glucose.

189425:PGRAT RS00990
gene id: 189425:PGRAT_RS00990
uniprot id: A0A089M1Z8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycyl radical enzyme (GRE) family. PFL subfamily.
messages: Catalyzes the conversion of pyruvate to formate and acetyl-CoA.
messages: Cytoplasm
messages: Homodimer.

189425:PGRAT RS06580
gene id: 189425:PGRAT_RS06580
uniprot id: A0A089M0Z9
names: Function
names: Similarity
messages: Belongs to the PurU family.
messages: Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).

189425:PGRAT RS10795
gene id: 189425:PGRAT_RS10795
uniprot id: A0A089M6Z2
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

189425:PGRAT RS21750
gene id: 189425:PGRAT_RS21750
uniprot id: A0A089MCQ9
names: Similarity
messages: Belongs to the AHA1 family.

189425:PGRAT RS20975
gene id: 189425:PGRAT_RS20975
uniprot id: A0A089MEX6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

189425:PGRAT RS11035
gene id: 189425:PGRAT_RS11035
uniprot id: A0A089M9I4
names: Subcellular Location Annotation
messages: Membrane

189425:PGRAT RS09535
gene id: 189425:PGRAT_RS09535
uniprot id: A0A089M8Y0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

189425:PGRAT RS17490
gene id: 189425:PGRAT_RS17490
uniprot id: A0A089NJZ5
names: Similarity
messages: Belongs to the peptidase M16 family.

189425:PGRAT RS20505
gene id: 189425:PGRAT_RS20505
uniprot id: A0A089M825
names: Similarity
messages: Belongs to the CdaR family.

189425:PGRAT RS17445
gene id: 189425:PGRAT_RS17445
uniprot id: A0A089MAH5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsK/SpoIIIE/SftA family.
messages: Homohexamer. Forms a ring that surrounds DNA.
messages: Membrane

189425:PGRAT RS23660
gene id: 189425:PGRAT_RS23660
uniprot id: A0A089MDQ9
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

189425:PGRAT RS01865
gene id: 189425:PGRAT_RS01865
uniprot id: A0A089NC96
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

189425:PGRAT RS16905
gene id: 189425:PGRAT_RS16905
uniprot id: A0A089MCQ0
names: Subcellular Location Annotation
messages: Membrane

189425:PGRAT RS19380
gene id: 189425:PGRAT_RS19380
uniprot id: A0A089M8X2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 5 family.
messages: Cell membrane
messages: Membrane

189425:PGRAT RS26935
gene id: 189425:PGRAT_RS26935
uniprot id: A0A089MFA0
names: Similarity
messages: Belongs to the pirin family.

189425:PGRAT RS26260
gene id: 189425:PGRAT_RS26260
uniprot id: A0A089NPF9
names: Subcellular Location Annotation
messages: Membrane

189425:PGRAT RS05000
gene id: 189425:PGRAT_RS05000
uniprot id: A0A089M6G4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

189425:PGRAT RS28245
gene id: 189425:PGRAT_RS28245
uniprot id: A0A089MDA5
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

189425:PGRAT RS00985
gene id: 189425:PGRAT_RS00985
uniprot id: A0A089NBW5
names: Similarity
messages: In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.
messages: In the N-terminal section; belongs to the aldehyde dehydrogenase family.

189425:PGRAT RS09685
gene id: 189425:PGRAT_RS09685
uniprot id: A0A089M2I2
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

189425:PGRAT RS07090
gene id: 189425:PGRAT_RS07090
uniprot id: A0A089M2T1
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

189425:PGRAT RS04895
gene id: 189425:PGRAT_RS04895
uniprot id: A0A089NDL7
names: Similarity
messages: Belongs to the Nudix hydrolase family.

189425:PGRAT RS28280
gene id: 189425:PGRAT_RS28280
uniprot id: A0A089NQD8
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

189425:PGRAT RS12880
gene id: 189425:PGRAT_RS12880
uniprot id: A0A089M410
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

189425:PGRAT RS28550
gene id: 189425:PGRAT_RS28550
uniprot id: A0A089NQJ3
names: Similarity
messages: Belongs to the polysaccharide synthase family.

189425:PGRAT RS04490
gene id: 189425:PGRAT_RS04490
uniprot id: A0A089NDG1
names: Subcellular Location Annotation
messages: Membrane

189425:PGRAT RS27415
gene id: 189425:PGRAT_RS27415
uniprot id: A0A089MFI6
names: Similarity
messages: Belongs to the methyltransferase superfamily. Arsenite methyltransferase family.

189425:PGRAT RS20440
gene id: 189425:PGRAT_RS20440
uniprot id: A0A089MEQ2
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

189425:PGRAT RS24150
gene id: 189425:PGRAT_RS24150
uniprot id: A0A089M9V0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

189425:PGRAT RS09185
gene id: 189425:PGRAT_RS09185
uniprot id: A0A089M8N4
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

189425:PGRAT RS05880
gene id: 189425:PGRAT_RS05880
uniprot id: A0A089NE50
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

189425:PGRAT RS27880
gene id: 189425:PGRAT_RS27880
uniprot id: A0A089NQ46
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

189425:PGRAT RS04020
gene id: 189425:PGRAT_RS04020
uniprot id: A0A089M650
names: Similarity
messages: Belongs to the band 7/mec-2 family.

189425:PGRAT RS05465
gene id: 189425:PGRAT_RS05465
uniprot id: A0A089NDX2
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

189425:PGRAT RS19035
gene id: 189425:PGRAT_RS19035
uniprot id: A0A089M8S0
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

189425:PGRAT RS10280
gene id: 189425:PGRAT_RS10280
uniprot id: A0A089M977
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

189425:PGRAT RS25290
gene id: 189425:PGRAT_RS25290
uniprot id: A0A089MBW0
names: Similarity
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Spore germination protein (SGP) (TC 2.A.3.9) family.

189425:PGRAT RS11620
gene id: 189425:PGRAT_RS11620
uniprot id: A0A089NGZ6
names: Cofactor
names: Similarity
messages: Belongs to the iron-containing alcohol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.

189425:PGRAT RS04275
gene id: 189425:PGRAT_RS04275
uniprot id: A0A089M1D9
names: Subcellular Location Annotation
messages: Membrane

189425:PGRAT RS08240
gene id: 189425:PGRAT_RS08240
uniprot id: A0A089M5P9
names: Similarity
messages: Belongs to the manganese catalase family.

189425:PGRAT RS07065
gene id: 189425:PGRAT_RS07065
uniprot id: A0A089M2S8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family.
messages: Membrane

189425:PGRAT RS07015
gene id: 189425:PGRAT_RS07015
uniprot id: A0A089M7L7
names: Similarity
messages: Belongs to the helicase family. RecQ subfamily.

189425:PGRAT RS29845
gene id: 189425:PGRAT_RS29845
uniprot id: A0A089ME43
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

189425:PGRAT RS25205
gene id: 189425:PGRAT_RS25205
uniprot id: A0A089MEH3
names: Function
names: Similarity
messages: Belongs to the radical SAM superfamily. NifB family.
messages: Involved in the biosynthesis of the iron-molybdenum cofactor (FeMo-co or M-cluster) found in the dinitrogenase enzyme of the nitrogenase complex in nitrogen-fixing microorganisms. NifB catalyzes the crucial step of radical SAM-dependent carbide insertion that occurs concomitant with the insertion of a 9th sulfur and the rearrangement/coupling of two [4Fe-4S] clusters into a [8Fe-9S-C] cluster, the precursor to the M-cluster.

189425:PGRAT RS24650
gene id: 189425:PGRAT_RS24650
uniprot id: A0A089NNK3
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

189425:PGRAT RS31025
gene id: 189425:PGRAT_RS31025
uniprot id: A0A089MEP4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

189425:PGRAT RS26340
gene id: 189425:PGRAT_RS26340
uniprot id: A0A089MHJ9
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.

189425:PGRAT RS00935
gene id: 189425:PGRAT_RS00935
uniprot id: A0A089M1V8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

189425:PGRAT RS14905
gene id: 189425:PGRAT_RS14905
uniprot id: A0A089M556
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

189425:PGRAT RS30060
gene id: 189425:PGRAT_RS30060
uniprot id: A0A089ME77
names: Similarity
messages: Belongs to the diacylglycerol/lipid kinase family.

189425:PGRAT RS25005
gene id: 189425:PGRAT_RS25005
uniprot id: A0A089MA94
names: Similarity
messages: Belongs to the asparagine synthetase family.

189425:PGRAT RS10110
gene id: 189425:PGRAT_RS10110
uniprot id: A0A089M4A9
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.