1871111:DJ533 RS07625
gene id: 1871111:DJ533_RS07625
uniprot id: A0A2S2FDR3
names: Subcellular Location Annotation
messages: Membrane

1871111:DJ533 RS01205
gene id: 1871111:DJ533_RS01205
uniprot id: A0A2S2F8Z6
names: Similarity
messages: Belongs to the GST superfamily.

1871111:DJ533 RS17445
gene id: 1871111:DJ533_RS17445
uniprot id: A0A2S2FGX3
names: Similarity
messages: Belongs to the UPF0301 (AlgH) family.

1871111:DJ533 RS18310
gene id: 1871111:DJ533_RS18310
uniprot id: A0A2S2FHD3
names: Subcellular Location Annotation
messages: Membrane

1871111:DJ533 RS14825
gene id: 1871111:DJ533_RS14825
uniprot id: A0A2S2FHB8
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.

1871111:DJ533 RS06700
gene id: 1871111:DJ533_RS06700
uniprot id: A0A2S2FBK5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
messages: Cell inner membrane
messages: Membrane

1871111:DJ533 RS10795
gene id: 1871111:DJ533_RS10795
uniprot id: A0A2S2FFC0
names: Similarity
messages: Belongs to the bacterial ring-hydroxylating dioxygenase beta subunit family.

1871111:DJ533 RS08015
gene id: 1871111:DJ533_RS08015
uniprot id: A0A2S2FDX9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TamA family.
messages: Cell outer membrane
messages: Membrane

1871111:DJ533 RS15645
gene id: 1871111:DJ533_RS15645
uniprot id: A0A2S2FG31
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.

1871111:DJ533 RS13605
gene id: 1871111:DJ533_RS13605
uniprot id: A0A2S2FEZ0
names: Cofactor
names: Similarity
messages: Belongs to the rubredoxin family.
messages: Binds 1 Fe(3+) ion per subunit.

1871111:DJ533 RS18220
gene id: 1871111:DJ533_RS18220
uniprot id: A0A2S2FJ31
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetyltransferase family. ArgA subfamily.
messages: Cytoplasm
messages: In bacteria which possess the bifunctional enzyme ornithine acetyltransferase/N-acetylglutamate synthase (ArgJ), ArgA fulfills an anaplerotic role.

1871111:DJ533 RS02085
gene id: 1871111:DJ533_RS02085
uniprot id: A0A2S2F977
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Aromatic acid:H(+) symporter (AAHS) (TC 2.A.1.15) family.
messages: Membrane

1871111:DJ533 RS12990
gene id: 1871111:DJ533_RS12990
uniprot id: A0A2S2FER0
names: Similarity
messages: Belongs to the UPF0102 family.

1871111:DJ533 RS17375
gene id: 1871111:DJ533_RS17375
uniprot id: A0A2S2FH24
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1871111:DJ533 RS11400
gene id: 1871111:DJ533_RS11400
uniprot id: A0A2S2FE05
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the malate synthase family. GlcB subfamily.
messages: Cytoplasm
messages: Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1871111:DJ533 RS05540
gene id: 1871111:DJ533_RS05540
uniprot id: A0A2S2FAU0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

1871111:DJ533 RS01020
gene id: 1871111:DJ533_RS01020
uniprot id: A0A2S2F8N6
names: Similarity
messages: Belongs to the aminoglycoside phosphotransferase family.

1871111:DJ533 RS14895
gene id: 1871111:DJ533_RS14895
uniprot id: A0A2S2FFL6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1871111:DJ533 RS09745
gene id: 1871111:DJ533_RS09745
uniprot id: A0A2S2FDF7
names: Similarity
messages: In the N-terminal section; belongs to the NADH:flavin oxidoreductase/NADH oxidase family.

1871111:DJ533 RS17155
gene id: 1871111:DJ533_RS17155
uniprot id: A0A2S2FII6
names: Function
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

1871111:DJ533 RS02030
gene id: 1871111:DJ533_RS02030
uniprot id: A0A2S2F997
names: Function
messages: Involved in the transposition of the insertion sequence.

1871111:DJ533 RS04350
gene id: 1871111:DJ533_RS04350
uniprot id: A0A2S2FAQ6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate synthase component I family.
messages: Heterotetramer consisting of two non-identical subunits: a beta subunit (TrpG) and a large alpha subunit (TrpE).
messages: Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia.

1871111:DJ533 RS02625
gene id: 1871111:DJ533_RS02625
uniprot id: A0A2S2F9C2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

1871111:DJ533 RS15000
gene id: 1871111:DJ533_RS15000
uniprot id: A0A2S2FFR0
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. SDR39U1 subfamily.

1871111:DJ533 RS08440
gene id: 1871111:DJ533_RS08440
uniprot id: A0A2S2FCA4
names: Function
names: Similarity
messages: Belongs to the transaldolase family. Type 1 subfamily.
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

1871111:DJ533 RS14685
gene id: 1871111:DJ533_RS14685
uniprot id: A0A2S2FFH8
names: Function
messages: Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors. CheA is autophosphorylated; it can transfer its phosphate group to either CheB or CheY.

1871111:DJ533 RS06350
gene id: 1871111:DJ533_RS06350
uniprot id: A0A2S2FBP3
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
messages: Allosterically activated by GTP.
messages: Belongs to the UPRTase family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.
messages: Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.

1871111:DJ533 RS13535
gene id: 1871111:DJ533_RS13535
uniprot id: A0A2S2FF39
names: Similarity
messages: Belongs to the AB hydrolase superfamily. Lipase family.

1871111:DJ533 RS07340
gene id: 1871111:DJ533_RS07340
uniprot id: A0A2S2FBP1
names: Subcellular Location Annotation
messages: Membrane

1871111:DJ533 RS13550
gene id: 1871111:DJ533_RS13550
uniprot id: A0A2S2FEY1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.

1871111:DJ533 RS15555
gene id: 1871111:DJ533_RS15555
uniprot id: A0A2S2FFY8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

1871111:DJ533 RS11175
gene id: 1871111:DJ533_RS11175
uniprot id: A0A2S2FFJ2
names: Similarity
messages: Belongs to the tRNA methyltransferase O family.

1871111:DJ533 RS18130
gene id: 1871111:DJ533_RS18130
uniprot id: A0A2S2FHU1
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

1871111:DJ533 RS16925
gene id: 1871111:DJ533_RS16925
uniprot id: A0A2S2FGN2
names: Caution
names: Similarity
messages: Belongs to the acetaldehyde dehydrogenase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1871111:DJ533 RS11035
gene id: 1871111:DJ533_RS11035
uniprot id: A0A2S2FDL6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal stress protein A family.
messages: Cytoplasm

1871111:DJ533 RS16325
gene id: 1871111:DJ533_RS16325
uniprot id: A0A2S2FGD4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Homohexamer.
messages: In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.
messages: In the N-terminal section; belongs to the CobB/CobQ family.
messages: Involved in acetate metabolism.
messages: The N-terminal region seems to be important for proper quaternary structure. The C-terminal region contains the substrate-binding site.

1871111:DJ533 RS02160
gene id: 1871111:DJ533_RS02160
uniprot id: A0A2S2F980
names: Function
names: Similarity
messages: Belongs to the MerB family.
messages: Cleaves the carbon-mercury bond of organomercurials such as phenylmercuric acetate. One product is Hg(2+), which is subsequently detoxified by the mercuric reductase.

1871111:DJ533 RS15720
gene id: 1871111:DJ533_RS15720
uniprot id: A0A2S2FG64
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

1871111:DJ533 RS14000
gene id: 1871111:DJ533_RS14000
uniprot id: A0A2S2FFD2
names: Subcellular Location Annotation
messages: Membrane

1871111:DJ533 RS04505
gene id: 1871111:DJ533_RS04505
uniprot id: A0A2S2FAG0
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit contributes ATPase, 3'-5' helicase, exonuclease activity and loads RecA onto ssDNA.
messages: Belongs to the helicase family. UvrD subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotrimer of RecB, RecC and RecD. All subunits contribute to DNA-binding. Interacts with RecA.
messages: The C-terminal domain has nuclease activity and interacts with RecD. It interacts with RecA, facilitating its loading onto ssDNA.
messages: The N-terminal DNA-binding domain is a ssDNA-dependent ATPase and has ATP-dependent 3'-5' helicase function. This domain interacts with RecC.

1871111:DJ533 RS15890
gene id: 1871111:DJ533_RS15890
uniprot id: A0A2S2FGC2
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

1871111:DJ533 RS05055
gene id: 1871111:DJ533_RS05055
uniprot id: A0A2S2FAL0
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1871111:DJ533 RS03390
gene id: 1871111:DJ533_RS03390
uniprot id: A0A2S2F9Q2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase group 1 family.
messages: Cell membrane
messages: Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP-Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A.

1871111:DJ533 RS18015
gene id: 1871111:DJ533_RS18015
uniprot id: A0A2S2FH70
names: Similarity
messages: Belongs to the phosphohexose mutase family.

1871111:DJ533 RS16130
gene id: 1871111:DJ533_RS16130
uniprot id: A0A2S2FGD7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YciB family.
messages: Cell inner membrane
messages: Plays a role in cell envelope biogenesis, maintenance of cell envelope integrity and membrane homeostasis.

1871111:DJ533 RS07685
gene id: 1871111:DJ533_RS07685
uniprot id: A0A2S2FBW4
names: Similarity
messages: Belongs to the ETF beta-subunit/FixA family.

1871111:DJ533 RS09730
gene id: 1871111:DJ533_RS09730
uniprot id: A0A2S2FCY5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LysR transcriptional regulatory family.
messages: Cytoplasm

1871111:DJ533 RS15350
gene id: 1871111:DJ533_RS15350
uniprot id: A0A2S2FG16
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FPG family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
messages: Monomer.

1871111:DJ533 RS04475
gene id: 1871111:DJ533_RS04475
uniprot id: A0A2S2FAA6
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2).

1871111:DJ533 RS07565
gene id: 1871111:DJ533_RS07565
uniprot id: A0A2S2FC19
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

1871111:DJ533 RS06345
gene id: 1871111:DJ533_RS06345
uniprot id: A0A2S2FB81
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 2 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1871111:DJ533 RS14555
gene id: 1871111:DJ533_RS14555
uniprot id: A0A2S2FFN4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

1871111:DJ533 RS15630
gene id: 1871111:DJ533_RS15630
uniprot id: A0A2S2FFZ0
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1871111:DJ533 RS09535
gene id: 1871111:DJ533_RS09535
uniprot id: A0A2S2FDB9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM175 family.
messages: Membrane

1871111:DJ533 RS12185
gene id: 1871111:DJ533_RS12185
uniprot id: A0A2S2FE91
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

1871111:DJ533 RS03840
gene id: 1871111:DJ533_RS03840
uniprot id: A0A2S2FAG5
names: Subcellular Location Annotation
messages: Membrane

1871111:DJ533 RS15145
gene id: 1871111:DJ533_RS15145
uniprot id: A0A2S2FFP1
names: Similarity
messages: Belongs to the GSP E family.

1871111:DJ533 RS14210
gene id: 1871111:DJ533_RS14210
uniprot id: A0A2S2FFT0
names: Similarity
messages: Belongs to the UbiH/COQ6 family.

1871111:DJ533 RS05965
gene id: 1871111:DJ533_RS05965
uniprot id: A0A2S2FB05
names: Similarity
messages: Belongs to the BolA/IbaG family.

1871111:DJ533 RS13740
gene id: 1871111:DJ533_RS13740
uniprot id: A0A2S2FFI9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DHBP synthase family.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Homodimer.

1871111:DJ533 RS15920
gene id: 1871111:DJ533_RS15920
uniprot id: A0A2S2FG38
names: Similarity
messages: Belongs to the MlaA family.

1871111:DJ533 RS09670
gene id: 1871111:DJ533_RS09670
uniprot id: A0A2S2FCW8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.
messages: Cytoplasm
messages: Homodimer. Forms a heterotetramer with IscU, interacts with other sulfur acceptors.
messages: Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins.

1871111:DJ533 RS09445
gene id: 1871111:DJ533_RS09445
uniprot id: A0A2S2FCW1
names: Similarity
messages: In the N-terminal section; belongs to the CRISPR-associated nuclease Cas3-HD family.
messages: In the central section; belongs to the CRISPR-associated helicase Cas3 family.

1871111:DJ533 RS13300
gene id: 1871111:DJ533_RS13300
uniprot id: A0A2S2FEU2
names: Subcellular Location Annotation
messages: Membrane

1871111:DJ533 RS08985
gene id: 1871111:DJ533_RS08985
uniprot id: A0A2S2FEE5
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1871111:DJ533 RS18020
gene id: 1871111:DJ533_RS18020
uniprot id: A0A2S2FHA0
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

1871111:DJ533 RS02405
gene id: 1871111:DJ533_RS02405
uniprot id: A0A2S2F8Z0
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1871111:DJ533 RS12320
gene id: 1871111:DJ533_RS12320
uniprot id: A0A2S2FEG6
names: Similarity
messages: Belongs to the PhzF family.

1871111:DJ533 RS14500
gene id: 1871111:DJ533_RS14500
uniprot id: A0A2S2FFI6
names: Similarity
messages: Belongs to the TrpF family.

1871111:DJ533 RS07805
gene id: 1871111:DJ533_RS07805
uniprot id: A0A2S2FBW5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SNF2/RAD54 helicase family. RapA subfamily.
messages: Interacts with the RNAP. Has a higher affinity for the core RNAP than for the holoenzyme. Its ATPase activity is stimulated by binding to RNAP.
messages: Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair.

1871111:DJ533 RS01470
gene id: 1871111:DJ533_RS01470
uniprot id: A0A2S2F8K6
names: Similarity
messages: Belongs to the GSP E family.

1871111:DJ533 RS06810
gene id: 1871111:DJ533_RS06810
uniprot id: A0A2S2FBH0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OmpP1/FadL family.
messages: Cell outer membrane
messages: Membrane

1871111:DJ533 RS17385
gene id: 1871111:DJ533_RS17385
uniprot id: A0A2S2FIM7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP E family.
messages: Cytoplasm

1871111:DJ533 RS18540
gene id: 1871111:DJ533_RS18540
uniprot id: A0A2S2FI20
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
messages: Binds 1 potassium ion per subunit.
messages: Cytoplasm
messages: Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1871111:DJ533 RS09870
gene id: 1871111:DJ533_RS09870
uniprot id: A0A2S2FDH6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KdpC family.
messages: Cell membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

1871111:DJ533 RS12425
gene id: 1871111:DJ533_RS12425
uniprot id: A0A2S2FEI6
names: Subcellular Location Annotation
messages: Membrane

1871111:DJ533 RS14230
gene id: 1871111:DJ533_RS14230
uniprot id: A0A2S2FFD4
names: Similarity
messages: Belongs to the peptidase M24B family.

1871111:DJ533 RS17930
gene id: 1871111:DJ533_RS17930
uniprot id: A0A2S2FH68
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Prokaryotic type I sub-subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
messages: Cell membrane
messages: Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The autoendoproteolytic cleavage occurs by a canonical serine protease mechanism, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain. During this reaction, the Ser that is part of the protease active site of the proenzyme becomes the pyruvoyl prosthetic group, which constitutes an essential element of the active site of the mature decarboxylase.

1871111:DJ533 RS15070
gene id: 1871111:DJ533_RS15070
uniprot id: A0A2S2FFP6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

1871111:DJ533 RS14430
gene id: 1871111:DJ533_RS14430
uniprot id: A0A2S2FFD7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1871111:DJ533 RS09965
gene id: 1871111:DJ533_RS09965
uniprot id: A0A2S2FD19
names: Subcellular Location Annotation
messages: Membrane

1871111:DJ533 RS09230
gene id: 1871111:DJ533_RS09230
uniprot id: A0A2S2FCV5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobS family.
messages: Cell membrane
messages: Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.
messages: Membrane

1871111:DJ533 RS07215
gene id: 1871111:DJ533_RS07215
uniprot id: A0A2S2FBL4
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TtcA family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is chelated by three Cys residues, the fourth Fe has a free coordination site that may bind a sulfur atom transferred from the persulfide of IscS.
messages: Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system.
messages: Cytoplasm
messages: Homodimer.
messages: The thiolation reaction likely consists of two steps: a first activation step by ATP to form an adenylated intermediate of the target base of tRNA, and a second nucleophilic substitution step of the sulfur (S) atom supplied by the hydrosulfide attached to the Fe-S cluster.

1871111:DJ533 RS18300
gene id: 1871111:DJ533_RS18300
uniprot id: A0A2S2FHD9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

1871111:DJ533 RS16370
gene id: 1871111:DJ533_RS16370
uniprot id: A0A2S2FGW6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

1871111:DJ533 RS06400
gene id: 1871111:DJ533_RS06400
uniprot id: A0A2S2FB89
names: Similarity
messages: Belongs to the ACC deaminase/D-cysteine desulfhydrase family.

1871111:DJ533 RS06295
gene id: 1871111:DJ533_RS06295
uniprot id: A0A2S2FB72
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Cell membrane
messages: In the C-terminal section; belongs to the complex I 49 kDa subunit family.
messages: In the N-terminal section; belongs to the complex I 30 kDa subunit family.
messages: NDH-1 is composed of 13 different subunits. Subunits NuoB, CD, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1871111:DJ533 RS09005
gene id: 1871111:DJ533_RS09005
uniprot id: A0A2S2FCI9
names: Similarity
messages: Belongs to the GPAT/DAPAT family.

1871111:DJ533 RS10275
gene id: 1871111:DJ533_RS10275
uniprot id: A0A2S2FDE4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsB family.
messages: Cell inner membrane
messages: Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.
messages: Part of a complex composed of FtsB, FtsL and FtsQ.

1871111:DJ533 RS05270
gene id: 1871111:DJ533_RS05270
uniprot id: A0A2S2FAP7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RlmJ family.
messages: Monomer.
messages: Specifically methylates the adenine in position 2030 of 23S rRNA.

1871111:DJ533 RS08695
gene id: 1871111:DJ533_RS08695
uniprot id: A0A2S2FCG6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate:Na(+) symporter (ESS) (TC 2.A.27) family.
messages: Catalyzes the sodium-dependent transport of glutamate.
messages: Cell inner membrane

1871111:DJ533 RS02820
gene id: 1871111:DJ533_RS02820
uniprot id: A0A2S2F9Q1
names: Subcellular Location Annotation
messages: Membrane

1871111:DJ533 RS01210
gene id: 1871111:DJ533_RS01210
uniprot id: A0A2S2F8K2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Membrane

1871111:DJ533 RS17395
gene id: 1871111:DJ533_RS17395
uniprot id: A0A2S2FGY5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A24 family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Plays an essential role in type IV pili and type II pseudopili formation by proteolytically removing the leader sequence from substrate proteins and subsequently monomethylating the alpha-amino group of the newly exposed N-terminal phenylalanine.

1871111:DJ533 RS16795
gene id: 1871111:DJ533_RS16795
uniprot id: A0A2S2FGS1
names: Function
names: Similarity
messages: Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage.
messages: Belongs to the Nudix hydrolase family. RppH subfamily.

1871111:DJ533 RS11375
gene id: 1871111:DJ533_RS11375
uniprot id: A0A2S2FE95
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

1871111:DJ533 RS07275
gene id: 1871111:DJ533_RS07275
uniprot id: A0A2S2FBR1
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

1871111:DJ533 RS10080
gene id: 1871111:DJ533_RS10080
uniprot id: A0A2S2FD42
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1871111:DJ533 RS13215
gene id: 1871111:DJ533_RS13215
uniprot id: A0A2S2FER7
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

1871111:DJ533 RS08305
gene id: 1871111:DJ533_RS08305
uniprot id: A0A2S2FCE0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1871111:DJ533 RS11315
gene id: 1871111:DJ533_RS11315
uniprot id: A0A2S2FE86
names: Activity Regulation
names: Caution
names: Domain
names: Function
names: Similarity
messages: Belongs to the GlnD family.
messages: Has four distinct domains: an N-terminal nucleotidyltransferase (NT) domain responsible for UTase activity, a central HD domain that encodes UR activity, and two C-terminal ACT domains that seem to have a role in glutamine sensing.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen metabolism.
messages: Uridylyltransferase (UTase) activity is inhibited by glutamine, while glutamine activates uridylyl-removing (UR) activity.

1871111:DJ533 RS13955
gene id: 1871111:DJ533_RS13955
uniprot id: A0A2S2FGY8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Membrane

1871111:DJ533 RS16625
gene id: 1871111:DJ533_RS16625
uniprot id: A0A2S2FGK8
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

1871111:DJ533 RS08875
gene id: 1871111:DJ533_RS08875
uniprot id: A0A2S2FCH3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ribose 5-phosphate isomerase family.
messages: Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
messages: Homodimer.

1871111:DJ533 RS07965
gene id: 1871111:DJ533_RS07965
uniprot id: A0A2S2FDX0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Mediates global changes in gene expression, shifting from rapid growth to stress survival by linking envelope stress, the stringent response and the catabolite repression systems. Usually binds in the 5'-UTR; binding at or near the Shine-Dalgarno sequence prevents ribosome-binding, repressing translation, binding elsewhere in the 5'-UTR can activate translation and/or stabilize the mRNA. Its function is antagonized by small RNA(s).
messages: Belongs to the CsrA/RsmA family.
messages: Cytoplasm
messages: Homodimer; the beta-strands of each monomer intercalate to form a hydrophobic core, while the alpha-helices form wings that extend away from the core.

1871111:DJ533 RS11130
gene id: 1871111:DJ533_RS11130
uniprot id: A0A2S2FDQ1
names: Function
names: Similarity
messages: Belongs to the LpxB family.
messages: Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

1871111:DJ533 RS15970
gene id: 1871111:DJ533_RS15970
uniprot id: A0A2S2FG48
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
messages: Single-chain monomer with multiple functions.

1871111:DJ533 RS04960
gene id: 1871111:DJ533_RS04960
uniprot id: A0A2S2FAI4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

1871111:DJ533 RS04985
gene id: 1871111:DJ533_RS04985
uniprot id: A0A2S2FAK2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

1871111:DJ533 RS07940
gene id: 1871111:DJ533_RS07940
uniprot id: A0A2S2FC26
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenine deaminase type 2 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism.

1871111:DJ533 RS10885
gene id: 1871111:DJ533_RS10885
uniprot id: A0A2S2FDR9
names: Similarity
messages: Belongs to the UPF0319 family.

1871111:DJ533 RS16410
gene id: 1871111:DJ533_RS16410
uniprot id: A0A2S2FGE2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AB hydrolase superfamily. MetX family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine.

1871111:DJ533 RS15425
gene id: 1871111:DJ533_RS15425
uniprot id: A0A2S2FFW4
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

1871111:DJ533 RS17315
gene id: 1871111:DJ533_RS17315
uniprot id: A0A2S2FGV4
names: Similarity
messages: Belongs to the N-Me-Phe pilin family.

1871111:DJ533 RS01490
gene id: 1871111:DJ533_RS01490
uniprot id: A0A2S2F8E0
names: Similarity
messages: Belongs to the ParB family.

1871111:DJ533 RS07620
gene id: 1871111:DJ533_RS07620
uniprot id: A0A2S2FBU0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 2 family.
messages: Cell membrane
messages: Membrane

1871111:DJ533 RS08575
gene id: 1871111:DJ533_RS08575
uniprot id: A0A2S2FCJ2
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

1871111:DJ533 RS08285
gene id: 1871111:DJ533_RS08285
uniprot id: A0A2S2FC73
names: Similarity
messages: Belongs to the Nudix hydrolase family.

1871111:DJ533 RS14180
gene id: 1871111:DJ533_RS14180
uniprot id: A0A2S2FFC1
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

1871111:DJ533 RS03395
gene id: 1871111:DJ533_RS03395
uniprot id: A0A2S2F9R3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

1871111:DJ533 RS17115
gene id: 1871111:DJ533_RS17115
uniprot id: A0A2S2FGS7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1871111:DJ533 RS06305
gene id: 1871111:DJ533_RS06305
uniprot id: A0A2S2FB61
names: Function
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.

1871111:DJ533 RS14245
gene id: 1871111:DJ533_RS14245
uniprot id: A0A2S2FH33
names: Function
names: Similarity
names: Subunit
messages: Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division.
messages: Belongs to the ZapA family. Type 1 subfamily.
messages: Homodimer. Interacts with FtsZ.

1871111:DJ533 RS05245
gene id: 1871111:DJ533_RS05245
uniprot id: A0A2S2FAN6
names: Function
names: Similarity
messages: Belongs to the LDH/MDH superfamily. MDH type 2 family.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.

1871111:DJ533 RS07880
gene id: 1871111:DJ533_RS07880
uniprot id: A0A2S2FBY0
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

1871111:DJ533 RS11445
gene id: 1871111:DJ533_RS11445
uniprot id: A0A2S2FDU0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

1871111:DJ533 RS10445
gene id: 1871111:DJ533_RS10445
uniprot id: A0A2S2FDA3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0702 family.
messages: Cell membrane
messages: Membrane

1871111:DJ533 RS15750
gene id: 1871111:DJ533_RS15750
uniprot id: A0A2S2FGL0
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1871111:DJ533 RS06065
gene id: 1871111:DJ533_RS06065
uniprot id: A0A2S2FB24
names: Function
names: Similarity
messages: Belongs to the esterase D family.
messages: Serine hydrolase involved in the detoxification of formaldehyde.

1871111:DJ533 RS04395
gene id: 1871111:DJ533_RS04395
uniprot id: A0A2S2FA94
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1871111:DJ533 RS17940
gene id: 1871111:DJ533_RS17940
uniprot id: A0A2S2FHD1
names: Function
names: PTM
names: Similarity
messages: Belongs to the NAPRTase family.
messages: Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP.
messages: Transiently phosphorylated on a His residue during the reaction cycle. Phosphorylation strongly increases the affinity for substrates and increases the rate of nicotinate D-ribonucleotide production. Dephosphorylation regenerates the low-affinity form of the enzyme, leading to product release.

1871111:DJ533 RS09600
gene id: 1871111:DJ533_RS09600
uniprot id: A0A2S2FD24
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1871111:DJ533 RS13925
gene id: 1871111:DJ533_RS13925
uniprot id: A0A2S2FF86
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell outer membrane

1871111:DJ533 RS06820
gene id: 1871111:DJ533_RS06820
uniprot id: A0A2S2FBE9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

1871111:DJ533 RS14155
gene id: 1871111:DJ533_RS14155
uniprot id: A0A2S2FFA5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.
messages: Cytoplasm
messages: Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.

1871111:DJ533 RS03630
gene id: 1871111:DJ533_RS03630
uniprot id: A0A2S2FA10
names: Caution
names: Function
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.

1871111:DJ533 RS04790
gene id: 1871111:DJ533_RS04790
uniprot id: A0A2S2FCB6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MlaE permease family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the ABC transporter complex MlaFEDB, which is involved in a phospholipid transport pathway that maintains lipid asymmetry in the outer membrane by retrograde trafficking of phospholipids from the outer membrane to the inner membrane. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (MlaF), two transmembrane proteins (MlaE), two cytoplasmic solute-binding proteins (MlaB) and six periplasmic solute-binding proteins (MlaD).

1871111:DJ533 RS16065
gene id: 1871111:DJ533_RS16065
uniprot id: A0A2S2FGE4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-to-5' exoribonuclease specific for small oligoribonucleotides.
messages: Belongs to the oligoribonuclease family.
messages: Cytoplasm

1871111:DJ533 RS05975
gene id: 1871111:DJ533_RS05975
uniprot id: A0A2S2FB86
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Lacks the C-terminal regulatory region which is replaced by HisZ.

1871111:DJ533 RS03930
gene id: 1871111:DJ533_RS03930
uniprot id: A0A2S2FA62
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.
messages: In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family.

1871111:DJ533 RS16385
gene id: 1871111:DJ533_RS16385
uniprot id: A0A2S2FGK5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1871111:DJ533 RS17570
gene id: 1871111:DJ533_RS17570
uniprot id: A0A2S2FGZ5
names: Subcellular Location Annotation
messages: Membrane

1871111:DJ533 RS16170
gene id: 1871111:DJ533_RS16170
uniprot id: A0A2S2FG91
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1871111:DJ533 RS13355
gene id: 1871111:DJ533_RS13355
uniprot id: A0A2S2FEW1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lactate permease family.
messages: Cell inner membrane
messages: Membrane
messages: Uptake of L-lactate across the membrane. Can also transport D-lactate and glycolate.

1871111:DJ533 RS16530
gene id: 1871111:DJ533_RS16530
uniprot id: A0A2S2FGG1
names: Function
names: Similarity
messages: Belongs to the PurU family.
messages: Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).

1871111:DJ533 RS14025
gene id: 1871111:DJ533_RS14025
uniprot id: A0A2S2FHS9
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

1871111:DJ533 RS07720
gene id: 1871111:DJ533_RS07720
uniprot id: A0A2S2FBW0
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1871111:DJ533 RS12360
gene id: 1871111:DJ533_RS12360
uniprot id: A0A2S2FEH2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

1871111:DJ533 RS17475
gene id: 1871111:DJ533_RS17475
uniprot id: A0A2S2FH32
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 1 subfamily.
messages: Cell membrane
messages: Heterotetramer composed of ParC and ParE.
messages: Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.

1871111:DJ533 RS04085
gene id: 1871111:DJ533_RS04085
uniprot id: A0A2S2FAB4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

1871111:DJ533 RS06115
gene id: 1871111:DJ533_RS06115
uniprot id: A0A2S2FB33
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

1871111:DJ533 RS17015
gene id: 1871111:DJ533_RS17015
uniprot id: A0A2S2FGP1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1871111:DJ533 RS03020
gene id: 1871111:DJ533_RS03020
uniprot id: A0A2S2F9I8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

1871111:DJ533 RS14060
gene id: 1871111:DJ533_RS14060
uniprot id: A0A2S2FFD0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

1871111:DJ533 RS03005
gene id: 1871111:DJ533_RS03005
uniprot id: A0A2S2F9I3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

1871111:DJ533 RS18195
gene id: 1871111:DJ533_RS18195
uniprot id: A0A2S2FHB2
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily. UbiG/COQ3 family.
messages: O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway.

1871111:DJ533 RS08670
gene id: 1871111:DJ533_RS08670
uniprot id: A0A2S2FCE4
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

1871111:DJ533 RS11550
gene id: 1871111:DJ533_RS11550
uniprot id: A0A2S2FDV6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the N7 position of guanine in position 527 of 16S rRNA.

1871111:DJ533 RS03090
gene id: 1871111:DJ533_RS03090
uniprot id: A0A2S2FHI1
names: Similarity
messages: Belongs to the RecJ family.

1871111:DJ533 RS03610
gene id: 1871111:DJ533_RS03610
uniprot id: A0A2S2F9U9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

1871111:DJ533 RS04880
gene id: 1871111:DJ533_RS04880
uniprot id: A0A2S2FAI6
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

1871111:DJ533 RS07960
gene id: 1871111:DJ533_RS07960
uniprot id: A0A2S2FHM8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

1871111:DJ533 RS15695
gene id: 1871111:DJ533_RS15695
uniprot id: A0A2S2FG41
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.

1871111:DJ533 RS08010
gene id: 1871111:DJ533_RS08010
uniprot id: A0A2S2FC10
names: Subcellular Location Annotation
messages: Membrane

1871111:DJ533 RS09220
gene id: 1871111:DJ533_RS09220
uniprot id: A0A2S2FCN4
names: Function
names: Similarity
messages: Belongs to the CobT family.
messages: Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB).

1871111:DJ533 RS02880
gene id: 1871111:DJ533_RS02880
uniprot id: A0A2S2FBE4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DoxX family.
messages: Membrane

1871111:DJ533 RS16145
gene id: 1871111:DJ533_RS16145
uniprot id: A0A2S2FI02
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Catalyzes the last two steps in the biosynthesis of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the DAO family.
messages: In the N-terminal section; belongs to the methyltransferase superfamily. tRNA (mnm(5)s(2)U34)-methyltransferase family.

1871111:DJ533 RS05080
gene id: 1871111:DJ533_RS05080
uniprot id: A0A2S2FAT6
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.

1871111:DJ533 RS15405
gene id: 1871111:DJ533_RS15405
uniprot id: A0A2S2FHV4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP H family.
messages: Cell inner membrane
messages: Membrane

1871111:DJ533 RS11475
gene id: 1871111:DJ533_RS11475
uniprot id: A0A2S2FDU3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP K family.
messages: Cell inner membrane
messages: Membrane

1871111:DJ533 RS06045
gene id: 1871111:DJ533_RS06045
uniprot id: A0A2S2FCZ5
names: Similarity
messages: Belongs to the KAE1 / TsaD family. TsaB subfamily.

1871111:DJ533 RS17990
gene id: 1871111:DJ533_RS17990
uniprot id: A0A2S2FHE0
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

1871111:DJ533 RS06725
gene id: 1871111:DJ533_RS06725
uniprot id: A0A2S2FBV7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

1871111:DJ533 RS12900
gene id: 1871111:DJ533_RS12900
uniprot id: A0A2S2FEK4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

1871111:DJ533 RS04405
gene id: 1871111:DJ533_RS04405
uniprot id: A0A2S2FA65
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1871111:DJ533 RS18405
gene id: 1871111:DJ533_RS18405
uniprot id: A0A2S2FHE4
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

1871111:DJ533 RS06945
gene id: 1871111:DJ533_RS06945
uniprot id: A0A2S2FDE0
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: May also have succinyldiaminopimelate aminotransferase activity, thus carrying out the corresponding step in lysine biosynthesis.

1871111:DJ533 RS09015
gene id: 1871111:DJ533_RS09015
uniprot id: A0A2S2FCR9
names: Similarity
messages: Belongs to the GSP E family.

1871111:DJ533 RS00710
gene id: 1871111:DJ533_RS00710
uniprot id: A0A2S2F8T1
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

1871111:DJ533 RS17775
gene id: 1871111:DJ533_RS17775
uniprot id: A0A2S2FH31
names: Similarity
messages: Belongs to the glutamate--cysteine ligase type 1 family. Type 1 subfamily.

1871111:DJ533 RS15960
gene id: 1871111:DJ533_RS15960
uniprot id: A0A2S2FGA8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Cell inner membrane
messages: Homoheptamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mechanosensitive channel that participates in the regulation of osmotic pressure changes within the cell, opening in response to stretch forces in the membrane lipid bilayer, without the need for other proteins. Contributes to normal resistance to hypoosmotic shock. Forms an ion channel of 1.0 nanosiemens conductance with a slight preference for anions.
messages: Membrane

1871111:DJ533 RS14755
gene id: 1871111:DJ533_RS14755
uniprot id: A0A2S2FFR3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

1871111:DJ533 RS04240
gene id: 1871111:DJ533_RS04240
uniprot id: A0A2S2FA59
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase class-III family.

1871111:DJ533 RS04930
gene id: 1871111:DJ533_RS04930
uniprot id: A0A2S2FAQ3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

1871111:DJ533 RS14980
gene id: 1871111:DJ533_RS14980
uniprot id: A0A2S2FFU5
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1871111:DJ533 RS11215
gene id: 1871111:DJ533_RS11215
uniprot id: A0A2S2FDT1
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1871111:DJ533 RS11240
gene id: 1871111:DJ533_RS11240
uniprot id: A0A2S2FDS2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phospholipase A1 family.
messages: Binds 1 Ca(2+) ion per monomer. In the dimeric form the Ca(2+) is bound by different amino acids with binding of each Ca(2+) shared with ligands coming from each monomer. The Ca(2+) ion may have a role in catalysis.
messages: Cell outer membrane
messages: Homodimer; dimerization is reversible, and the dimeric form is the active one.
messages: Hydrolysis of phosphatidylcholine with phospholipase A2 (EC 3.1.1.4) and phospholipase A1 (EC 3.1.1.32) activities.
messages: Membrane

1871111:DJ533 RS11465
gene id: 1871111:DJ533_RS11465
uniprot id: A0A2S2FDT8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
messages: Cytoplasm
messages: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.

1871111:DJ533 RS05740
gene id: 1871111:DJ533_RS05740
uniprot id: A0A2S2FCU5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0073 (Hly-III) family.
messages: Membrane

1871111:DJ533 RS18030
gene id: 1871111:DJ533_RS18030
uniprot id: A0A2S2FH88
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

1871111:DJ533 RS02775
gene id: 1871111:DJ533_RS02775
uniprot id: A0A2S2FHK1
names: Function
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.
messages: DNA-dependent ATPase that plays important roles in cellular responses to stalled DNA replication processes.

1871111:DJ533 RS16550
gene id: 1871111:DJ533_RS16550
uniprot id: A0A2S2FGF7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

1871111:DJ533 RS12755
gene id: 1871111:DJ533_RS12755
uniprot id: A0A2S2FGD3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Membrane

1871111:DJ533 RS07925
gene id: 1871111:DJ533_RS07925
uniprot id: A0A2S2FBY5
names: Function
names: Similarity
messages: Belongs to the HPPK family.
messages: Catalyzes the transfer of pyrophosphate from adenosine triphosphate (ATP) to 6-hydroxymethyl-7,8-dihydropterin, an enzymatic step in folate biosynthesis pathway.

1871111:DJ533 RS02530
gene id: 1871111:DJ533_RS02530
uniprot id: A0A2S2FHG9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 2 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1871111:DJ533 RS17925
gene id: 1871111:DJ533_RS17925
uniprot id: A0A2S2FHP3
names: Function
messages: Member of the two-component regulatory system PhoR/PhoB involved in the phosphate regulon genes expression. PhoR may function as a membrane-associated protein kinase that phosphorylates PhoB in response to environmental signals.

1871111:DJ533 RS13540
gene id: 1871111:DJ533_RS13540
uniprot id: A0A2S2FF14
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family.
messages: Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate.
messages: Cell inner membrane

1871111:DJ533 RS06930
gene id: 1871111:DJ533_RS06930
uniprot id: A0A2S2FBJ2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SurE nucleotidase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Cytoplasm
messages: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.

1871111:DJ533 RS18040
gene id: 1871111:DJ533_RS18040
uniprot id: A0A2S2FHE9
names: Similarity
messages: Belongs to the bacterial sugar transferase family.

1871111:DJ533 RS18225
gene id: 1871111:DJ533_RS18225
uniprot id: A0A2S2FHA8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein SsuA/TauA family.
messages: Periplasm

1871111:DJ533 RS09090
gene id: 1871111:DJ533_RS09090
uniprot id: A0A2S2FCL5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbC subfamily.
messages: Periplasm
messages: Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process.

1871111:DJ533 RS02185
gene id: 1871111:DJ533_RS02185
uniprot id: A0A2S2F906
names: Function
messages: Mediates the mercuric-dependent induction of mercury resistance operon. In the absence of mercury MerR represses transcription by binding tightly to the mer operator region; when mercury is present the dimeric complex binds a single ion and becomes a potent transcriptional activator, while remaining bound to the mer site.

1871111:DJ533 RS06595
gene id: 1871111:DJ533_RS06595
uniprot id: A0A2S2FBA8
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

1871111:DJ533 RS04730
gene id: 1871111:DJ533_RS04730
uniprot id: A0A2S2FAC3
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1871111:DJ533 RS07150
gene id: 1871111:DJ533_RS07150
uniprot id: A0A2S2FBT7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 2 subfamily.
messages: Cytoplasm
messages: Homotetramer.

1871111:DJ533 RS16510
gene id: 1871111:DJ533_RS16510
uniprot id: A0A2S2FGG5
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

1871111:DJ533 RS16715
gene id: 1871111:DJ533_RS16715
uniprot id: A0A2S2FH27
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1871111:DJ533 RS07540
gene id: 1871111:DJ533_RS07540
uniprot id: A0A2S2FBR7
names: Similarity
messages: Belongs to the peptidase S49 family.

1871111:DJ533 RS09245
gene id: 1871111:DJ533_RS09245
uniprot id: A0A2S2FCN9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1871111:DJ533 RS14400
gene id: 1871111:DJ533_RS14400
uniprot id: A0A2S2FFJ7
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

1871111:DJ533 RS13345
gene id: 1871111:DJ533_RS13345
uniprot id: A0A2S2FFC4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.
messages: Catalyzes the conversion of L-lactate to pyruvate. Is coupled to the respiratory chain.
messages: Cell membrane

1871111:DJ533 RS09555
gene id: 1871111:DJ533_RS09555
uniprot id: A0A2S2FCY0
names: Similarity
messages: Belongs to the intradiol ring-cleavage dioxygenase family.

1871111:DJ533 RS04500
gene id: 1871111:DJ533_RS04500
uniprot id: A0A2S2FAB5
names: Function
names: Similarity
names: Subunit
messages: A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild-type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity.
messages: Belongs to the RecC family.
messages: Heterotrimer of RecB, RecC and RecD. All subunits contribute to DNA-binding.

1871111:DJ533 RS04130
gene id: 1871111:DJ533_RS04130
uniprot id: A0A2S2FA39
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M17 family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm
messages: Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.

1871111:DJ533 RS11520
gene id: 1871111:DJ533_RS11520
uniprot id: A0A2S2FE23
names: Function
names: Similarity
messages: Belongs to the LpxK family.
messages: Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).

1871111:DJ533 RS11740
gene id: 1871111:DJ533_RS11740
uniprot id: A0A2S2FE59
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1871111:DJ533 RS17275
gene id: 1871111:DJ533_RS17275
uniprot id: A0A2S2FGV9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1871111:DJ533 RS15780
gene id: 1871111:DJ533_RS15780
uniprot id: A0A2S2FG19
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1871111:DJ533 RS04390
gene id: 1871111:DJ533_RS04390
uniprot id: A0A2S2FAG3
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

1871111:DJ533 RS16080
gene id: 1871111:DJ533_RS16080
uniprot id: A0A2S2FG68
names: Function
names: Similarity
messages: Belongs to the glutaredoxin family.
messages: Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins.

1871111:DJ533 RS06770
gene id: 1871111:DJ533_RS06770
uniprot id: A0A2S2FBE0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
messages: Membrane

1871111:DJ533 RS11835
gene id: 1871111:DJ533_RS11835
uniprot id: A0A2S2FE41
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1871111:DJ533 RS05830
gene id: 1871111:DJ533_RS05830
uniprot id: A0A2S2FB66
names: Similarity
messages: Belongs to the folylpolyglutamate synthase family.

1871111:DJ533 RS15520
gene id: 1871111:DJ533_RS15520
uniprot id: A0A2S2FG25
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamB family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

1871111:DJ533 RS07185
gene id: 1871111:DJ533_RS07185
uniprot id: A0A2S2FBK8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Membrane

1871111:DJ533 RS18560
gene id: 1871111:DJ533_RS18560
uniprot id: A0A2S2FHP1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

1871111:DJ533 RS17300
gene id: 1871111:DJ533_RS17300
uniprot id: A0A2S2FGU4
names: Subcellular Location Annotation
messages: Membrane

1871111:DJ533 RS05820
gene id: 1871111:DJ533_RS05820
uniprot id: A0A2S2FAY5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

1871111:DJ533 RS17510
gene id: 1871111:DJ533_RS17510
uniprot id: A0A2S2FGZ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

1871111:DJ533 RS12025
gene id: 1871111:DJ533_RS12025
uniprot id: A0A2S2FE66
names: Subcellular Location Annotation
messages: Virion

1871111:DJ533 RS08500
gene id: 1871111:DJ533_RS08500
uniprot id: A0A2S2FCA2
names: Caution
names: Function
names: Similarity
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1871111:DJ533 RS12385
gene id: 1871111:DJ533_RS12385
uniprot id: A0A2S2FG61
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class II aldolase/RraA-like family.
messages: Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2-oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions.
messages: Homotrimer.

1871111:DJ533 RS05525
gene id: 1871111:DJ533_RS05525
uniprot id: A0A2S2FCQ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YajC family.
messages: Cell inner membrane
messages: Membrane

1871111:DJ533 RS15155
gene id: 1871111:DJ533_RS15155
uniprot id: A0A2S2FFR2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamE family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

1871111:DJ533 RS10935
gene id: 1871111:DJ533_RS10935
uniprot id: A0A2S2FDN3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvC family.
messages: Binds 2 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer which binds Holliday junction (HJ) DNA. The HJ becomes 2-fold symmetrical on binding to RuvC with unstacked arms; it has a different conformation from HJ DNA in complex with RuvA. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair. Endonuclease that resolves HJ intermediates. Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction. The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'. Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange. HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

1871111:DJ533 RS17450
gene id: 1871111:DJ533_RS17450
uniprot id: A0A2S2FGZ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

1871111:DJ533 RS13665
gene id: 1871111:DJ533_RS13665
uniprot id: A0A2S2FEZ4
names: Subunit
messages: Homodimer.

1871111:DJ533 RS09635
gene id: 1871111:DJ533_RS09635
uniprot id: A0A2S2FCX4
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1871111:DJ533 RS09700
gene id: 1871111:DJ533_RS09700
uniprot id: A0A2S2FCX0
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

1871111:DJ533 RS12335
gene id: 1871111:DJ533_RS12335
uniprot id: A0A2S2FEA8
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

1871111:DJ533 RS13210
gene id: 1871111:DJ533_RS13210
uniprot id: A0A2S2FEZ3
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

1871111:DJ533 RS11590
gene id: 1871111:DJ533_RS11590
uniprot id: A0A2S2FDY5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm

1871111:DJ533 RS07170
gene id: 1871111:DJ533_RS07170
uniprot id: A0A2S2FBL8
names: Similarity
messages: Belongs to the PrpF family.

1871111:DJ533 RS05705
gene id: 1871111:DJ533_RS05705
uniprot id: A0A2S2FBD3
names: Subcellular Location Annotation
messages: Membrane

1871111:DJ533 RS11820
gene id: 1871111:DJ533_RS11820
uniprot id: A0A2S2FE10
names: Similarity
names: Subunit
messages: Belongs to the muconolactone Delta-isomerase family.
messages: Homodecamer.

1871111:DJ533 RS07300
gene id: 1871111:DJ533_RS07300
uniprot id: A0A2S2FBP2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein bS6.

1871111:DJ533 RS15865
gene id: 1871111:DJ533_RS15865
uniprot id: A0A2S2FGM9
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

1871111:DJ533 RS14450
gene id: 1871111:DJ533_RS14450
uniprot id: A0A2S2FFK7
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

1871111:DJ533 RS07690
gene id: 1871111:DJ533_RS07690
uniprot id: A0A2S2FCD5
names: Cofactor
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.
messages: Binds 1 FAD per dimer.

1871111:DJ533 RS10985
gene id: 1871111:DJ533_RS10985
uniprot id: A0A2S2FDR5
names: Similarity
messages: Belongs to the TmoD/XamoD family.

1871111:DJ533 RS02715
gene id: 1871111:DJ533_RS02715
uniprot id: A0A2S2F9H2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1871111:DJ533 RS17410
gene id: 1871111:DJ533_RS17410
uniprot id: A0A2S2FGW8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. RlmB subfamily.
messages: Cytoplasm
messages: Specifically methylates the ribose of guanosine 2251 in 23S rRNA.

1871111:DJ533 RS13835
gene id: 1871111:DJ533_RS13835
uniprot id: A0A2S2FGX1
names: Subcellular Location Annotation
messages: Membrane

1871111:DJ533 RS13820
gene id: 1871111:DJ533_RS13820
uniprot id: A0A2S2FF66
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LipB family.
messages: Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
messages: Cytoplasm
messages: In the reaction, the free carboxyl group of octanoic acid is attached via an amide linkage to the epsilon-amino group of a specific lysine residue of lipoyl domains of lipoate-dependent enzymes.

1871111:DJ533 RS15230
gene id: 1871111:DJ533_RS15230
uniprot id: A0A2S2FFT3
names: Function
names: Similarity
messages: Belongs to the MinE family.
messages: Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.

1871111:DJ533 RS15810
gene id: 1871111:DJ533_RS15810
uniprot id: A0A2S2FG43
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PNT beta subunit family.
messages: Cell inner membrane
messages: Heterodimer of an alpha and a beta chain.
messages: Membrane
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

1871111:DJ533 RS15185
gene id: 1871111:DJ533_RS15185
uniprot id: A0A2S2FFZ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm

1871111:DJ533 RS03645
gene id: 1871111:DJ533_RS03645
uniprot id: A0A2S2F9V0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

1871111:DJ533 RS15295
gene id: 1871111:DJ533_RS15295
uniprot id: A0A2S2FFY6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

1871111:DJ533 RS17265
gene id: 1871111:DJ533_RS17265
uniprot id: A0A2S2FGW3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

1871111:DJ533 RS03450
gene id: 1871111:DJ533_RS03450
uniprot id: A0A2S2F9S5
names: Similarity
messages: Belongs to the SsuE family.

1871111:DJ533 RS04645
gene id: 1871111:DJ533_RS04645
uniprot id: A0A2S2FAC9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA gyrase inhibitor YacG family.
messages: Binds 1 zinc ion.
messages: Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase.
messages: Interacts with GyrB.

1871111:DJ533 RS13705
gene id: 1871111:DJ533_RS13705
uniprot id: A0A2S2FHT2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family.
messages: Cytoplasm
messages: Homotrimer.

1871111:DJ533 RS05320
gene id: 1871111:DJ533_RS05320
uniprot id: A0A2S2FAP5
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1871111:DJ533 RS14670
gene id: 1871111:DJ533_RS14670
uniprot id: A0A2S2FFH5
names: Similarity
messages: Belongs to the EcnA/EcnB lipoprotein family.

1871111:DJ533 RS02965
gene id: 1871111:DJ533_RS02965
uniprot id: A0A2S2FA05
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PDR/VanB family. CntB subfamily.
messages: Binds 1 2Fe-2S cluster.
messages: Composed of an oxygenase subunit and a reductase subunit.
messages: Converts carnitine to trimethylamine and malic semialdehyde.

1871111:DJ533 RS07630
gene id: 1871111:DJ533_RS07630
uniprot id: A0A2S2FBV0
names: Function
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.
messages: Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate.

1871111:DJ533 RS07730
gene id: 1871111:DJ533_RS07730
uniprot id: A0A2S2FBW7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1871111:DJ533 RS14090
gene id: 1871111:DJ533_RS14090
uniprot id: A0A2S2FF94
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.

1871111:DJ533 RS16400
gene id: 1871111:DJ533_RS16400
uniprot id: A0A2S2FGC7
names: Similarity
messages: Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.

1871111:DJ533 RS06685
gene id: 1871111:DJ533_RS06685
uniprot id: A0A2S2FBK7
names: Similarity
messages: Belongs to the citrate synthase family.

1871111:DJ533 RS13000
gene id: 1871111:DJ533_RS13000
uniprot id: A0A2S2FEU7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

1871111:DJ533 RS05450
gene id: 1871111:DJ533_RS05450
uniprot id: A0A2S2FAY2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbC subfamily.
messages: Periplasm
messages: Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process.

1871111:DJ533 RS11280
gene id: 1871111:DJ533_RS11280
uniprot id: A0A2S2FDU4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Cell inner membrane
messages: Membrane

1871111:DJ533 RS01220
gene id: 1871111:DJ533_RS01220
uniprot id: A0A2S2FAH2
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily.

1871111:DJ533 RS13120
gene id: 1871111:DJ533_RS13120
uniprot id: A0A2S2FGK0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PNP synthase family.
messages: Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.
messages: Cytoplasm
messages: Homooctamer; tetramer of dimers.

1871111:DJ533 RS01275
gene id: 1871111:DJ533_RS01275
uniprot id: A0A2S2F8I0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome b560 family.
messages: Membrane
messages: Membrane-anchoring subunit of succinate dehydrogenase (SDH).
messages: Part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur protein, plus two membrane-anchoring proteins, SdhC and SdhD. The complex can form homotrimers.
messages: The heme is bound between the two transmembrane subunits.

1871111:DJ533 RS08725
gene id: 1871111:DJ533_RS08725
uniprot id: A0A2S2FHU2
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

1871111:DJ533 RS13125
gene id: 1871111:DJ533_RS13125
uniprot id: A0A2S2FEQ5
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

1871111:DJ533 RS05825
gene id: 1871111:DJ533_RS05825
uniprot id: A0A2S2FAY7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccD/PCCB family.
messages: Binds 1 zinc ion per subunit.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

1871111:DJ533 RS10310
gene id: 1871111:DJ533_RS10310
uniprot id: A0A2S2FDQ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DsrE/TusD family.
messages: Cytoplasm

1871111:DJ533 RS03040
gene id: 1871111:DJ533_RS03040
uniprot id: A0A2S2F9Q4
names: Function
messages: Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).

1871111:DJ533 RS08155
gene id: 1871111:DJ533_RS08155
uniprot id: A0A2S2FC63
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0382 family.
messages: Membrane

1871111:DJ533 RS03520
gene id: 1871111:DJ533_RS03520
uniprot id: A0A2S2FA22
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 zinc ion per subunit.

1871111:DJ533 RS18430
gene id: 1871111:DJ533_RS18430
uniprot id: A0A2S2FI01
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)- to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Homodimer.

1871111:DJ533 RS10290
gene id: 1871111:DJ533_RS10290
uniprot id: A0A2S2FD80
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1871111:DJ533 RS15385
gene id: 1871111:DJ533_RS15385
uniprot id: A0A2S2FFW3
names: Subcellular Location Annotation
messages: Membrane

1871111:DJ533 RS10395
gene id: 1871111:DJ533_RS10395
uniprot id: A0A2S2FDG5
names: Similarity
messages: Belongs to the ClpA/ClpB family.

1871111:DJ533 RS07000
gene id: 1871111:DJ533_RS07000
uniprot id: A0A2S2FBJ1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ExbD/TolR family.
messages: Cell inner membrane
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

1871111:DJ533 RS04135
gene id: 1871111:DJ533_RS04135
uniprot id: A0A2S2FA67
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptF/LptG family.
messages: Cell inner membrane
messages: Component of the lipopolysaccharide transport and assembly complex. The LptBFG transporter is composed of two ATP-binding proteins (LptB) and two transmembrane proteins (LptF and LptG).
messages: Membrane
messages: Part of the ABC transporter complex LptBFG involved in the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane.

1871111:DJ533 RS18520
gene id: 1871111:DJ533_RS18520
uniprot id: A0A2S2FHG1
names: Similarity
messages: Belongs to the FrmR/RcnR family.

1871111:DJ533 RS04685
gene id: 1871111:DJ533_RS04685
uniprot id: A0A2S2FAE2
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type B subfamily.
messages: Part of the 50S ribosomal subunit.

1871111:DJ533 RS07290
gene id: 1871111:DJ533_RS07290
uniprot id: A0A2S2FBM9
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins.

1871111:DJ533 RS09645
gene id: 1871111:DJ533_RS09645
uniprot id: A0A2S2FCW2
names: Similarity
messages: Belongs to the adrenodoxin/putidaredoxin family.

1871111:DJ533 RS17995
gene id: 1871111:DJ533_RS17995
uniprot id: A0A2S2FHC3
names: Caution
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the thiamine-monophosphate kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate.

1871111:DJ533 RS04615
gene id: 1871111:DJ533_RS04615
uniprot id: A0A2S2FAI0
names: Cofactor
names: Function
messages: Accepts electrons from ETF and reduces ubiquinone.
messages: Binds 1 [4Fe-4S] cluster.

1871111:DJ533 RS04180
gene id: 1871111:DJ533_RS04180
uniprot id: A0A2S2FAN5
names: Function
names: Similarity
messages: Belongs to the threonine synthase family.
messages: Catalyzes the gamma-elimination of phosphate from L-phosphohomoserine and the beta-addition of water to produce L-threonine.

1871111:DJ533 RS07705
gene id: 1871111:DJ533_RS07705
uniprot id: A0A2S2FC37
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

1871111:DJ533 RS04740
gene id: 1871111:DJ533_RS04740
uniprot id: A0A2S2FAE1
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the shikimate dehydrogenase family.
messages: Homodimer.
messages: Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1871111:DJ533 RS08595
gene id: 1871111:DJ533_RS08595
uniprot id: A0A2S2FCB8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

1871111:DJ533 RS02065
gene id: 1871111:DJ533_RS02065
uniprot id: A0A2S2F929
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Bcr/CmlA family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1871111:DJ533 RS15525
gene id: 1871111:DJ533_RS15525
uniprot id: A0A2S2FG46
names: Similarity
messages: Belongs to the YfgM family.

1871111:DJ533 RS06780
gene id: 1871111:DJ533_RS06780
uniprot id: A0A2S2FBF1
names: Subcellular Location Annotation
messages: Membrane

1871111:DJ533 RS13035
gene id: 1871111:DJ533_RS13035
uniprot id: A0A2S2FEQ0
names: Subcellular Location Annotation
messages: Membrane

1871111:DJ533 RS07600
gene id: 1871111:DJ533_RS07600
uniprot id: A0A2S2FBT4
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
messages: Carbon 2 of the heme B porphyrin ring is defined according to the Fischer nomenclature.
messages: Cell membrane
messages: Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
messages: Membrane

1871111:DJ533 RS18495
gene id: 1871111:DJ533_RS18495
uniprot id: A0A2S2FHF9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. ATZ/TRZ family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia.

1871111:DJ533 RS11585
gene id: 1871111:DJ533_RS11585
uniprot id: A0A2S2FDW2
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

1871111:DJ533 RS08915
gene id: 1871111:DJ533_RS08915
uniprot id: A0A2S2FHQ6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1871111:DJ533 RS13045
gene id: 1871111:DJ533_RS13045
uniprot id: A0A2S2FES0
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

1871111:DJ533 RS17780
gene id: 1871111:DJ533_RS17780
uniprot id: A0A2S2FH56
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DsbB family.
messages: Cell inner membrane
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein.

1871111:DJ533 RS08120
gene id: 1871111:DJ533_RS08120
uniprot id: A0A2S2FDZ2
names: Similarity
messages: Belongs to the radical SAM superfamily. KamA family.

1871111:DJ533 RS13295
gene id: 1871111:DJ533_RS13295
uniprot id: A0A2S2FFB3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1871111:DJ533 RS12825
gene id: 1871111:DJ533_RS12825
uniprot id: A0A2S2FEK8
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

1871111:DJ533 RS15190
gene id: 1871111:DJ533_RS15190
uniprot id: A0A2S2FFW7
names: Similarity
messages: Belongs to the phosphohexose mutase family.

1871111:DJ533 RS15150
gene id: 1871111:DJ533_RS15150
uniprot id: A0A2S2FHH1
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Fur family.
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.

1871111:DJ533 RS15040
gene id: 1871111:DJ533_RS15040
uniprot id: A0A2S2FFM7
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MGMT family.
messages: Cytoplasm
messages: Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
messages: This enzyme catalyzes only one turnover and therefore is not strictly catalytic. According to one definition, an enzyme is a biocatalyst that acts repeatedly and over many reaction cycles.

1871111:DJ533 RS18330
gene id: 1871111:DJ533_RS18330
uniprot id: A0A2S2FHD2
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

1871111:DJ533 RS17330
gene id: 1871111:DJ533_RS17330
uniprot id: A0A2S2FHY6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LemA family.
messages: Membrane

1871111:DJ533 RS17515
gene id: 1871111:DJ533_RS17515
uniprot id: A0A2S2FGY6
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1871111:DJ533 RS14010
gene id: 1871111:DJ533_RS14010
uniprot id: A0A2S2FGZ4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Catalyzes the sodium-dependent uptake of extracellular L-proline.
messages: Cell inner membrane
messages: Membrane

1871111:DJ533 RS04385
gene id: 1871111:DJ533_RS04385
uniprot id: A0A2S2FAA1
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1871111:DJ533 RS04955
gene id: 1871111:DJ533_RS04955
uniprot id: A0A2S2FAI2
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

1871111:DJ533 RS06855
gene id: 1871111:DJ533_RS06855
uniprot id: A0A2S2FBF0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.
messages: Heterodimer composed of CysD, the smaller subunit, and CysN.
messages: With CysD forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway. APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD.

1871111:DJ533 RS05970
gene id: 1871111:DJ533_RS05970
uniprot id: A0A2S2FB04
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1871111:DJ533 RS13850
gene id: 1871111:DJ533_RS13850
uniprot id: A0A2S2FFM8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S-adenosyl-L-methionine to the 2'-OH of the wobble nucleotide.

1871111:DJ533 RS15200
gene id: 1871111:DJ533_RS15200
uniprot id: A0A2S2FFQ7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. UvrD subfamily.
messages: Homodimer.
messages: Rep helicase is a single-stranded DNA-dependent ATPase involved in DNA replication; it can initiate unwinding at a nick in the DNA. It binds to the single-stranded DNA and acts in a progressive fashion along the DNA in the 3' to 5' direction.

1871111:DJ533 RS16155
gene id: 1871111:DJ533_RS16155
uniprot id: A0A2S2FGB4
names: Similarity
messages: Belongs to the UPF0234 family.

1871111:DJ533 RS13195
gene id: 1871111:DJ533_RS13195
uniprot id: A0A2S2FES8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MreD family.
messages: Membrane

1871111:DJ533 RS07020
gene id: 1871111:DJ533_RS07020
uniprot id: A0A2S2FBJ0
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvB family.
messages: Cytoplasm
messages: Has 3 domains, the large (RuvB-L) and small ATPase (RuvB-S) domains and the C-terminal head (RuvB-H) domain. The head domain binds DNA, while the ATPase domains jointly bind ATP, ADP or are empty depending on the state of the subunit in the translocation cycle. During a single DNA translocation step the structure of each domain remains the same, but their relative positions change.
messages: Homohexamer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time. Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange. Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration. The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration. Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.

1871111:DJ533 RS09025
gene id: 1871111:DJ533_RS09025
uniprot id: A0A2S2FCT9
names: Similarity
messages: Belongs to the nitroreductase family.

1871111:DJ533 RS04920
gene id: 1871111:DJ533_RS04920
uniprot id: A0A2S2FAI3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

1871111:DJ533 RS09810
gene id: 1871111:DJ533_RS09810
uniprot id: A0A2S2FCZ3
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1871111:DJ533 RS08125
gene id: 1871111:DJ533_RS08125
uniprot id: A0A2S2FC36
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Alleviates ribosome stalling that occurs when 3 or more consecutive Pro residues or the sequence PPG is present in a protein, possibly by augmenting the peptidyl transferase activity of the ribosome. Modification of Lys-34 is required for alleviation.
messages: May be beta-lysylated on the epsilon-amino group of Lys-34 by the combined action of EpmA and EpmB, and then hydroxylated on the C5 position of the same residue by EpmC (if this protein is present). Lysylation is critical for the stimulatory effect of EF-P on peptide-bond formation. The lysylation moiety may extend toward the peptidyltransferase center and stabilize the terminal 3-CCA end of the tRNA. Hydroxylation of the C5 position on Lys-34 may allow additional potential stabilizing hydrogen-bond interactions with the P-tRNA.

1871111:DJ533 RS05850
gene id: 1871111:DJ533_RS05850
uniprot id: A0A2S2FCW7
names: Similarity
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
messages: Belongs to the peroxiredoxin family. Prx6 subfamily.

1871111:DJ533 RS17585
gene id: 1871111:DJ533_RS17585
uniprot id: A0A2S2FH54
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.
messages: Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.
messages: Cytoplasm
messages: Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).
messages: The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.
messages: The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1.

1871111:DJ533 RS04840
gene id: 1871111:DJ533_RS04840
uniprot id: A0A2S2FAE8
names: Function
names: Similarity
messages: Belongs to the helicase family. RecG subfamily.
messages: Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA).

1871111:DJ533 RS12810
gene id: 1871111:DJ533_RS12810
uniprot id: A0A2S2FEK0
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1871111:DJ533 RS11540
gene id: 1871111:DJ533_RS11540
uniprot id: A0A2S2FDX4
names: Function
names: Similarity
messages: Belongs to the ParB family.
messages: Involved in chromosome partition. Localize to both poles of the predivisional cell following completion of DNA replication. Binds to the DNA origin of replication.

1871111:DJ533 RS09640
gene id: 1871111:DJ533_RS09640
uniprot id: A0A2S2FDD7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

1871111:DJ533 RS10950
gene id: 1871111:DJ533_RS10950
uniprot id: A0A2S2FFF1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.

1871111:DJ533 RS09665
gene id: 1871111:DJ533_RS09665
uniprot id: A0A2S2FD58
names: Function
names: Similarity
messages: A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters.
messages: Belongs to the NifU family.

1871111:DJ533 RS15605
gene id: 1871111:DJ533_RS15605
uniprot id: A0A2S2FG01
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptE lipoprotein family.
messages: Cell outer membrane
messages: Component of the lipopolysaccharide transport and assembly complex. Interacts with LptD.
messages: Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane.

1871111:DJ533 RS04915
gene id: 1871111:DJ533_RS04915
uniprot id: A0A2S2FAZ9
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: Methylated by PrmB.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

1871111:DJ533 RS13710
gene id: 1871111:DJ533_RS13710
uniprot id: A0A2S2FF82
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.
messages: Binds 1 S-adenosyl-L-methionine per subunit.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1871111:DJ533 RS11015
gene id: 1871111:DJ533_RS11015
uniprot id: A0A2S2FFG2
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1871111:DJ533 RS18260
gene id: 1871111:DJ533_RS18260
uniprot id: A0A2S2FHH8
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

1871111:DJ533 RS04080
gene id: 1871111:DJ533_RS04080
uniprot id: A0A2S2FA56
names: Similarity
messages: Belongs to the P(II) protein family.

1871111:DJ533 RS10385
gene id: 1871111:DJ533_RS10385
uniprot id: A0A2S2FD94
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family.
messages: Binds 1 Mg(2+) ion per subunit. Can also utilize other divalent metal cations, such as Ca(2+), Mn(2+) and Co(2+).
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
messages: Homodimer.

1871111:DJ533 RS07005
gene id: 1871111:DJ533_RS07005
uniprot id: A0A2S2FBJ9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ExbB/TolQ family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

1871111:DJ533 RS04660
gene id: 1871111:DJ533_RS04660
uniprot id: A0A2S2FAE3
names: Similarity
messages: Belongs to the Gfa family.

1871111:DJ533 RS14335
gene id: 1871111:DJ533_RS14335
uniprot id: A0A2S2FFI2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

1871111:DJ533 RS06310
gene id: 1871111:DJ533_RS06310
uniprot id: A0A2S2FB69
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the complex I 75 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: Composed of 13 different subunits. Subunits NuoCD, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1871111:DJ533 RS14300
gene id: 1871111:DJ533_RS14300
uniprot id: A0A2S2FH42
names: Subcellular Location Annotation
messages: Membrane

1871111:DJ533 RS02770
gene id: 1871111:DJ533_RS02770
uniprot id: A0A2S2FHH3
names: Similarity
messages: Belongs to the UPF0260 family.

1871111:DJ533 RS03565
gene id: 1871111:DJ533_RS03565
uniprot id: A0A2S2F9W6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family. T3SS ATPase subfamily.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

1871111:DJ533 RS06605
gene id: 1871111:DJ533_RS06605
uniprot id: A0A2S2FBB6
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

1871111:DJ533 RS02910
gene id: 1871111:DJ533_RS02910
uniprot id: A0A2S2F9R4
names: Similarity
messages: Belongs to the BolA/IbaG family.

1871111:DJ533 RS09655
gene id: 1871111:DJ533_RS09655
uniprot id: A0A2S2FD34
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HscB family.
messages: Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA.
messages: Interacts with HscA and stimulates its ATPase activity.

1871111:DJ533 RS08420
gene id: 1871111:DJ533_RS08420
uniprot id: A0A2S2FC88
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the branched chain amino acid transporter family.
messages: Cell inner membrane
messages: Component of the transport system for branched-chain amino acids.
messages: Membrane

1871111:DJ533 RS08885
gene id: 1871111:DJ533_RS08885
uniprot id: A0A2S2FCI0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the calycin superfamily. Lipocalin family.
messages: Cell outer membrane
messages: Homodimer.
messages: Involved in the storage or transport of lipids necessary for membrane maintenance under stressful conditions. Displays a binding preference for lysophospholipids.

1871111:DJ533 RS06540
gene id: 1871111:DJ533_RS06540
uniprot id: A0A2S2FBS6
names: Activity Regulation
names: Caution
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Inhibited by fructose 1,6-bisphosphate (FBP).
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1871111:DJ533 RS07075
gene id: 1871111:DJ533_RS07075
uniprot id: A0A2S2FBS9
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1871111:DJ533 RS17390
gene id: 1871111:DJ533_RS17390
uniprot id: A0A2S2FGW4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Cell inner membrane
messages: Membrane

1871111:DJ533 RS11750
gene id: 1871111:DJ533_RS11750
uniprot id: A0A2S2FFU3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
messages: Cell membrane
messages: Monomer.

1871111:DJ533 RS15370
gene id: 1871111:DJ533_RS15370
uniprot id: A0A2S2FFV4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

1871111:DJ533 RS04900
gene id: 1871111:DJ533_RS04900
uniprot id: A0A2S2FHJ7
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1871111:DJ533 RS05010
gene id: 1871111:DJ533_RS05010
uniprot id: A0A2S2FAJ0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

1871111:DJ533 RS09660
gene id: 1871111:DJ533_RS09660
uniprot id: A0A2S2FD07
names: Similarity
messages: Belongs to the HesB/IscA family.

1871111:DJ533 RS01140
gene id: 1871111:DJ533_RS01140
uniprot id: A0A2S2F8L2
names: Function
names: Similarity
messages: Belongs to the dihydrofolate reductase family.
messages: Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.

1871111:DJ533 RS10030
gene id: 1871111:DJ533_RS10030
uniprot id: A0A2S2FD32
names: Similarity
messages: Belongs to the GST superfamily. NadH family.

1871111:DJ533 RS08900
gene id: 1871111:DJ533_RS08900
uniprot id: A0A2S2FCH1
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1871111:DJ533 RS05175
gene id: 1871111:DJ533_RS05175
uniprot id: A0A2S2FAN7
names: Similarity
messages: Belongs to the WrbA family.

1871111:DJ533 RS08635
gene id: 1871111:DJ533_RS08635
uniprot id: A0A2S2FCC3
names: Similarity
messages: Belongs to the UPF0246 family.

1871111:DJ533 RS12395
gene id: 1871111:DJ533_RS12395
uniprot id: A0A2S2FED8
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

1871111:DJ533 RS14660
gene id: 1871111:DJ533_RS14660
uniprot id: A0A2S2FFH1
names: Subcellular Location Annotation
messages: Cell inner membrane

1871111:DJ533 RS16655
gene id: 1871111:DJ533_RS16655
uniprot id: A0A2S2FGQ4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCF family. Uup subfamily.
messages: Cytoplasm
messages: Probably plays a role in ribosome assembly or function. May be involved in resolution of branched DNA intermediates that result from template switching in postreplication gaps. Binds DNA and has ATPase activity.

1871111:DJ533 RS05045
gene id: 1871111:DJ533_RS05045
uniprot id: A0A2S2FAH9
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

1871111:DJ533 RS13005
gene id: 1871111:DJ533_RS13005
uniprot id: A0A2S2FEM9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal stress protein A family.
messages: Cytoplasm

1871111:DJ533 RS02005
gene id: 1871111:DJ533_RS02005
uniprot id: A0A2S2F922
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1871111:DJ533 RS16450
gene id: 1871111:DJ533_RS16450
uniprot id: A0A2S2FGD8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell membrane
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

1871111:DJ533 RS04565
gene id: 1871111:DJ533_RS04565
uniprot id: A0A2S2FA96
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.

1871111:DJ533 RS15990
gene id: 1871111:DJ533_RS15990
uniprot id: A0A2S2FGP8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccA family.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

1871111:DJ533 RS03160
gene id: 1871111:DJ533_RS03160
uniprot id: A0A2S2F9L5
names: Similarity
messages: Belongs to the GST superfamily.

1871111:DJ533 RS10095
gene id: 1871111:DJ533_RS10095
uniprot id: A0A2S2FD83
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

1871111:DJ533 RS15220
gene id: 1871111:DJ533_RS15220
uniprot id: A0A2S2FGB0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MinC family.
messages: Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization.
messages: Interacts with MinD and FtsZ.

1871111:DJ533 RS07315
gene id: 1871111:DJ533_RS07315
uniprot id: A0A2S2FBN1
names: Similarity
messages: Belongs to the GARS family.

1871111:DJ533 RS04865
gene id: 1871111:DJ533_RS04865
uniprot id: A0A2S2FAG7
names: Subcellular Location Annotation
messages: Membrane

1871111:DJ533 RS03050
gene id: 1871111:DJ533_RS03050
uniprot id: A0A2S2FBH2
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GDT1 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1871111:DJ533 RS05955
gene id: 1871111:DJ533_RS05955
uniprot id: A0A2S2FB13
names: Function
names: Similarity
messages: Belongs to the sigma-54 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

1871111:DJ533 RS16465
gene id: 1871111:DJ533_RS16465
uniprot id: A0A2S2FGH9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell membrane

1871111:DJ533 RS07520
gene id: 1871111:DJ533_RS07520
uniprot id: A0A2S2FDP4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

1871111:DJ533 RS09720
gene id: 1871111:DJ533_RS09720
uniprot id: A0A2S2FCX8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

1871111:DJ533 RS08300
gene id: 1871111:DJ533_RS08300
uniprot id: A0A2S2FC62
names: Function
names: Similarity
messages: Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits).
messages: In the C-terminal section; belongs to the transpeptidase family.
messages: In the N-terminal section; belongs to the glycosyltransferase 51 family.

1871111:DJ533 RS18235
gene id: 1871111:DJ533_RS18235
uniprot id: A0A2S2FHD8
names: Function
names: Similarity
messages: Belongs to the SsuD family.
messages: Catalyzes the desulfonation of aliphatic sulfonates.

1871111:DJ533 RS10400
gene id: 1871111:DJ533_RS10400
uniprot id: A0A2S2FDC9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ClpS family.
messages: Binds to the N-terminal domain of the chaperone ClpA.
messages: Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation.

1871111:DJ533 RS02110
gene id: 1871111:DJ533_RS02110
uniprot id: A0A2S2F9I2
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

1871111:DJ533 RS13890
gene id: 1871111:DJ533_RS13890
uniprot id: A0A2S2FGY1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

1871111:DJ533 RS04910
gene id: 1871111:DJ533_RS04910
uniprot id: A0A2S2FAH6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

1871111:DJ533 RS00390
gene id: 1871111:DJ533_RS00390
uniprot id: A0A2S2F8L4
names: Similarity
messages: Belongs to the glycosyl hydrolase 24 family.

1871111:DJ533 RS17110
gene id: 1871111:DJ533_RS17110
uniprot id: A0A2S2FH96
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Cu-Zn superoxide dismutase family.
messages: Binds 1 copper ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

1871111:DJ533 RS13755
gene id: 1871111:DJ533_RS13755
uniprot id: A0A2S2FF16
names: Function
names: Similarity
messages: Belongs to the TrhO family.
messages: Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs.

1871111:DJ533 RS15270
gene id: 1871111:DJ533_RS15270
uniprot id: A0A2S2FFV6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the R-transferase family. Bpt subfamily.
messages: Cytoplasm
messages: Functions in the N-end rule pathway of protein degradation where it conjugates Leu from its aminoacyl-tRNA to the N-termini of proteins containing an N-terminal aspartate or glutamate.

1871111:DJ533 RS16105
gene id: 1871111:DJ533_RS16105
uniprot id: A0A2S2FGA4
names: Similarity
messages: Belongs to the cytochrome b562 family.

1871111:DJ533 RS09490
gene id: 1871111:DJ533_RS09490
uniprot id: A0A2S2FD06
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inositol monophosphatase superfamily. CysQ family.
messages: Cell inner membrane
messages: Converts adenosine-3',5'-bisphosphate (PAP) to AMP.

1871111:DJ533 RS16950
gene id: 1871111:DJ533_RS16950
uniprot id: A0A2S2FGV1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase E/G family. RNase E subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per homotetramer.
messages: Cell inner membrane
messages: Component of the RNA degradosome, which is a multiprotein complex involved in RNA processing and mRNA degradation. Within the RNA degradosome, RNase E assembles into a homotetramer formed by a dimer of dimers.
messages: Cytoplasm
messages: Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs.

1871111:DJ533 RS12830
gene id: 1871111:DJ533_RS12830
uniprot id: A0A2S2FEL3
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

1871111:DJ533 RS02995
gene id: 1871111:DJ533_RS02995
uniprot id: A0A2S2F9H9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).

1871111:DJ533 RS14525
gene id: 1871111:DJ533_RS14525
uniprot id: A0A2S2FFH4
names: Similarity
messages: Belongs to the DODA-type extradiol aromatic ring-opening dioxygenase family.

1871111:DJ533 RS11530
gene id: 1871111:DJ533_RS11530
uniprot id: A0A2S2FFR1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

1871111:DJ533 RS12895
gene id: 1871111:DJ533_RS12895
uniprot id: A0A2S2FES9
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

1871111:DJ533 RS02475
gene id: 1871111:DJ533_RS02475
uniprot id: A0A2S2F8V0
names: Similarity
messages: Belongs to the phosphate/phosphite/phosphonate binding protein family.

1871111:DJ533 RS17195
gene id: 1871111:DJ533_RS17195
uniprot id: A0A2S2FGZ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lipase chaperone family.
messages: Cell inner membrane
messages: May be involved in the folding of the extracellular lipase during its passage through the periplasm.

1871111:DJ533 RS04575
gene id: 1871111:DJ533_RS04575
uniprot id: A0A2S2FAB2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP G family.
messages: Cell inner membrane
messages: Membrane

1871111:DJ533 RS12260
gene id: 1871111:DJ533_RS12260
uniprot id: A0A2S2FEE8
names: Similarity
messages: Belongs to the asparaginase 1 family.

1871111:DJ533 RS16895
gene id: 1871111:DJ533_RS16895
uniprot id: A0A2S2FGU1
names: Similarity
messages: Belongs to the bacterial ring-hydroxylating dioxygenase alpha subunit family.

1871111:DJ533 RS02795
gene id: 1871111:DJ533_RS02795
uniprot id: A0A2S2F9F4
names: Subcellular Location Annotation
messages: Membrane

1871111:DJ533 RS04320
gene id: 1871111:DJ533_RS04320
uniprot id: A0A2S2FA84
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone-like protein H-NS family.
messages: nucleoid

1871111:DJ533 RS08370
gene id: 1871111:DJ533_RS08370
uniprot id: A0A2S2FC79
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1871111:DJ533 RS08515
gene id: 1871111:DJ533_RS08515
uniprot id: A0A2S2FCD7
names: Similarity
messages: Belongs to the Skp family.

1871111:DJ533 RS04980
gene id: 1871111:DJ533_RS04980
uniprot id: A0A2S2FAR3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

1871111:DJ533 RS11685
gene id: 1871111:DJ533_RS11685
uniprot id: A0A2S2FDY8
names: Similarity
messages: Belongs to the HSP15 family.

1871111:DJ533 RS16000
gene id: 1871111:DJ533_RS16000
uniprot id: A0A2S2FG58
names: Similarity
messages: Belongs to the thioredoxin family.

1871111:DJ533 RS06180
gene id: 1871111:DJ533_RS06180
uniprot id: A0A2S2FB52
names: Function
names: Similarity
messages: Belongs to the SELO family.
messages: Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr or Tyr residues of target proteins (AMPylation).

1871111:DJ533 RS13620
gene id: 1871111:DJ533_RS13620
uniprot id: A0A2S2FF15
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1871111:DJ533 RS08160
gene id: 1871111:DJ533_RS08160
uniprot id: A0A2S2FCC0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoH subfamily.
messages: Cytoplasm
messages: Interacts with the RNA polymerase core enzyme.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes.

1871111:DJ533 RS00505
gene id: 1871111:DJ533_RS00505
uniprot id: A0A2S2F8Q1
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

1871111:DJ533 RS16490
gene id: 1871111:DJ533_RS16490
uniprot id: A0A2S2FGK7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

1871111:DJ533 RS07140
gene id: 1871111:DJ533_RS07140
uniprot id: A0A2S2FBT8
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

1871111:DJ533 RS02285
gene id: 1871111:DJ533_RS02285
uniprot id: A0A2S2F958
names: Similarity
messages: Belongs to the TmoD/XamoD family.

1871111:DJ533 RS03915
gene id: 1871111:DJ533_RS03915
uniprot id: A0A2S2FA28
names: Similarity
messages: Belongs to the HipA Ser/Thr kinase family.

1871111:DJ533 RS07200
gene id: 1871111:DJ533_RS07200
uniprot id: A0A2S2FBP4
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Membrane

1871111:DJ533 RS05000
gene id: 1871111:DJ533_RS05000
uniprot id: A0A2S2FCF6
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

1871111:DJ533 RS06710
gene id: 1871111:DJ533_RS06710
uniprot id: A0A2S2FDA0
names: Function
names: Similarity
messages: Belongs to the alpha-ketoglutarate dehydrogenase family.
messages: E1 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the decarboxylation of 2-oxoglutarate, the first step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).

1871111:DJ533 RS08005
gene id: 1871111:DJ533_RS08005
uniprot id: A0A2S2FC90
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COQ7 family.
messages: Binds 2 iron ions per subunit.
messages: Catalyzes the hydroxylation of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol during ubiquinone biosynthesis.
messages: Cell membrane

1871111:DJ533 RS10195
gene id: 1871111:DJ533_RS10195
uniprot id: A0A2S2FF11
names: Subcellular Location Annotation
messages: Membrane

1871111:DJ533 RS17985
gene id: 1871111:DJ533_RS17985
uniprot id: A0A2S2FH72
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.
messages: Forms an icosahedral capsid composed of 60 subunits, arranged as a dodecamer of pentamers.

1871111:DJ533 RS08145
gene id: 1871111:DJ533_RS08145
uniprot id: A0A2S2FC32
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ThiG family.
messages: Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
messages: Cytoplasm
messages: Homotetramer. Forms heterodimers with either ThiH or ThiS.

1871111:DJ533 RS11655
gene id: 1871111:DJ533_RS11655
uniprot id: A0A2S2FDY7
names: Subcellular Location Annotation
messages: Membrane

1871111:DJ533 RS15275
gene id: 1871111:DJ533_RS15275
uniprot id: A0A2S2FGC0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acetylates the N-terminal alanine of ribosomal protein bS18.
messages: Belongs to the acetyltransferase family. RimI subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1871111:DJ533 RS18375
gene id: 1871111:DJ533_RS18375
uniprot id: A0A2S2FHZ0
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

1871111:DJ533 RS11440
gene id: 1871111:DJ533_RS11440
uniprot id: A0A2S2FDT6
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS1 family.
messages: Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence.

1871111:DJ533 RS08095
gene id: 1871111:DJ533_RS08095
uniprot id: A0A2S2FC21
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the glyoxalase I family.
messages: Binds 1 nickel ion per subunit.
messages: Binds 1 zinc ion per subunit. In the homodimer, two zinc ions are bound between subunits.
messages: Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione.

1871111:DJ533 RS00970
gene id: 1871111:DJ533_RS00970
uniprot id: A0A2S2F8M5
names: Subcellular Location Annotation
messages: Cytoplasm

1871111:DJ533 RS12305
gene id: 1871111:DJ533_RS12305
uniprot id: A0A2S2FEA7
names: Similarity
messages: Belongs to the peptidase M16 family.

1871111:DJ533 RS16540
gene id: 1871111:DJ533_RS16540
uniprot id: A0A2S2FGL7
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1871111:DJ533 RS12760
gene id: 1871111:DJ533_RS12760
uniprot id: A0A2S2FEI9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

1871111:DJ533 RS10175
gene id: 1871111:DJ533_RS10175
uniprot id: A0A2S2FDC4
names: Similarity
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.

1871111:DJ533 RS17875
gene id: 1871111:DJ533_RS17875
uniprot id: A0A2S2FH52
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SUA5 family. TsaC subfamily.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Catalyzes the conversion of L-threonine, HCO(3)(-)/CO(2) and ATP to give threonylcarbamoyl-AMP (TC-AMP) as the acyladenylate intermediate, with the release of diphosphate.

1871111:DJ533 RS16260
gene id: 1871111:DJ533_RS16260
uniprot id: A0A2S2FGD6
names: Function
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.
messages: Catalyzes the isomerization of citrate to isocitrate via cis-aconitate.

1871111:DJ533 RS12355
gene id: 1871111:DJ533_RS12355
uniprot id: A0A2S2FEB7
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1871111:DJ533 RS04270
gene id: 1871111:DJ533_RS04270
uniprot id: A0A2S2FA45
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

1871111:DJ533 RS16585
gene id: 1871111:DJ533_RS16585
uniprot id: A0A2S2FGH2
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

1871111:DJ533 RS02885
gene id: 1871111:DJ533_RS02885
uniprot id: A0A2S2F9G4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Membrane

1871111:DJ533 RS15680
gene id: 1871111:DJ533_RS15680
uniprot id: A0A2S2FG00
names: Similarity
messages: Belongs to the GST superfamily.

1871111:DJ533 RS15820
gene id: 1871111:DJ533_RS15820
uniprot id: A0A2S2FGA7
names: Function
names: Similarity
messages: Belongs to the AlaDH/PNT family.
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

1871111:DJ533 RS07175
gene id: 1871111:DJ533_RS07175
uniprot id: A0A2S2FBM5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial diacylglycerol kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of sn-l,2-diacylglycerol (DAG) to phosphatidic acid. Involved in the recycling of diacylglycerol produced as a by-product during membrane-derived oligosaccharide (MDO) biosynthesis.
messages: Cell inner membrane
messages: Membrane
messages: Mn(2+), Zn(2+), Cd(2+) and Co(2+) support activity to lesser extents.

1871111:DJ533 RS17650
gene id: 1871111:DJ533_RS17650
uniprot id: A0A2S2FH73
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

1871111:DJ533 RS03360
gene id: 1871111:DJ533_RS03360
uniprot id: A0A2S2F9S7
names: Similarity
messages: Belongs to the DNA/RNA non-specific endonuclease family.

1871111:DJ533 RS10375
gene id: 1871111:DJ533_RS10375
uniprot id: A0A2S2FD90
names: Similarity
messages: Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily.

1871111:DJ533 RS04715
gene id: 1871111:DJ533_RS04715
uniprot id: A0A2S2FAF3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

1871111:DJ533 RS06370
gene id: 1871111:DJ533_RS06370
uniprot id: A0A2S2FBG1
names: Similarity
messages: Belongs to the ferredoxin--NADP reductase type 1 family.

1871111:DJ533 RS17050
gene id: 1871111:DJ533_RS17050
uniprot id: A0A2S2FGS6
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1871111:DJ533 RS06050
gene id: 1871111:DJ533_RS06050
uniprot id: A0A2S2FB35
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane
messages: Membrane

1871111:DJ533 RS04890
gene id: 1871111:DJ533_RS04890
uniprot id: A0A2S2FAF6
names: Caution
names: Similarity
messages: Belongs to the globin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1871111:DJ533 RS16830
gene id: 1871111:DJ533_RS16830
uniprot id: A0A2S2FGL3
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1871111:DJ533 RS09395
gene id: 1871111:DJ533_RS09395
uniprot id: A0A2S2FD08
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

1871111:DJ533 RS07650
gene id: 1871111:DJ533_RS07650
uniprot id: A0A2S2FBU5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

1871111:DJ533 RS03555
gene id: 1871111:DJ533_RS03555
uniprot id: A0A2S2FAB8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family. T3SS ATPase subfamily.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has four main subunits: a(1), b(1), b'(1) and c(9-12).
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

1871111:DJ533 RS17955
gene id: 1871111:DJ533_RS17955
uniprot id: A0A2S2FH60
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

1871111:DJ533 RS04100
gene id: 1871111:DJ533_RS04100
uniprot id: A0A2S2FA91
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

1871111:DJ533 RS11095
gene id: 1871111:DJ533_RS11095
uniprot id: A0A2S2FDM9
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1871111:DJ533 RS11570
gene id: 1871111:DJ533_RS11570
uniprot id: A0A2S2FE36
names: Domain
names: Function
names: Subcellular Location Annotation
messages: Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation.
messages: Periplasm
messages: The PPIase activity resides only in the second parvulin domain. The N-terminal region and the C-terminal tail are necessary and sufficient for the chaperone activity of SurA. The PPIase activity is dispensable for SurA to function as a chaperone. The N-terminal region and the C-terminal tail are also required for porin recognition.

1871111:DJ533 RS10285
gene id: 1871111:DJ533_RS10285
uniprot id: A0A2S2FDG4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KdsA family.
messages: Cytoplasm

1871111:DJ533 RS08735
gene id: 1871111:DJ533_RS08735
uniprot id: A0A2S2FCE3
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

1871111:DJ533 RS11800
gene id: 1871111:DJ533_RS11800
uniprot id: A0A2S2FFV1
names: Similarity
messages: Belongs to the outer membrane porin (Opr) (TC 1.B.25) family.

1871111:DJ533 RS04245
gene id: 1871111:DJ533_RS04245
uniprot id: A0A2S2FA85
names: Function
names: Similarity
messages: Acts on ADP-mannose and ADP-glucose as well as ADP-ribose. Prevents glycogen biosynthesis. The reaction catalyzed by this enzyme is a limiting step of the gluconeogenic process.
messages: Belongs to the Nudix hydrolase family. NudF subfamily.

1871111:DJ533 RS03870
gene id: 1871111:DJ533_RS03870
uniprot id: A0A2S2FA52
names: Subcellular Location Annotation
messages: Membrane

1871111:DJ533 RS03740
gene id: 1871111:DJ533_RS03740
uniprot id: A0A2S2FA60
names: Subcellular Location Annotation
messages: Membrane

1871111:DJ533 RS07070
gene id: 1871111:DJ533_RS07070
uniprot id: A0A2S2FBJ8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family. GltP subfamily.
messages: Catalyzes the proton-dependent transport of glutamate and aspartate.
messages: Cell inner membrane
messages: Membrane

1871111:DJ533 RS11775
gene id: 1871111:DJ533_RS11775
uniprot id: A0A2S2FE08
names: Cofactor
names: Similarity
messages: Belongs to the nitroreductase family.
messages: Binds 1 FMN per subunit.

1871111:DJ533 RS07980
gene id: 1871111:DJ533_RS07980
uniprot id: A0A2S2FCI4
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

1871111:DJ533 RS13565
gene id: 1871111:DJ533_RS13565
uniprot id: A0A2S2FF06
names: Subcellular Location Annotation
messages: Membrane

1871111:DJ533 RS08165
gene id: 1871111:DJ533_RS08165
uniprot id: A0A2S2FC40
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

1871111:DJ533 RS14390
gene id: 1871111:DJ533_RS14390
uniprot id: A0A2S2FFJ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family.
messages: Cell membrane
messages: Membrane

1871111:DJ533 RS15115
gene id: 1871111:DJ533_RS15115
uniprot id: A0A2S2FFQ6
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.

1871111:DJ533 RS11180
gene id: 1871111:DJ533_RS11180
uniprot id: A0A2S2FDP3
names: Similarity
messages: Belongs to the ferredoxin--NADP reductase type 1 family.

1871111:DJ533 RS02935
gene id: 1871111:DJ533_RS02935
uniprot id: A0A2S2F9N4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1871111:DJ533 RS05115
gene id: 1871111:DJ533_RS05115
uniprot id: A0A2S2FB38
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.
messages: Belongs to the RNR ribonuclease family. RNase R subfamily.
messages: Cytoplasm

1871111:DJ533 RS00570
gene id: 1871111:DJ533_RS00570
uniprot id: A0A2S2F8D3
names: Similarity
messages: Belongs to the MobA/MobL family.

1871111:DJ533 RS06705
gene id: 1871111:DJ533_RS06705
uniprot id: A0A2S2FBC7
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.

1871111:DJ533 RS13450
gene id: 1871111:DJ533_RS13450
uniprot id: A0A2S2FEV7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

1871111:DJ533 RS11515
gene id: 1871111:DJ533_RS11515
uniprot id: A0A2S2FDY3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
messages: Belongs to the KdsB family.
messages: Cytoplasm

1871111:DJ533 RS05030
gene id: 1871111:DJ533_RS05030
uniprot id: A0A2S2FAS7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

1871111:DJ533 RS13515
gene id: 1871111:DJ533_RS13515
uniprot id: A0A2S2FFF0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

1871111:DJ533 RS03465
gene id: 1871111:DJ533_RS03465
uniprot id: A0A2S2F9U6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

1871111:DJ533 RS16780
gene id: 1871111:DJ533_RS16780
uniprot id: A0A2S2FGK3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1871111:DJ533 RS08265
gene id: 1871111:DJ533_RS08265
uniprot id: A0A2S2FCD8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Monomer.
messages: Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl-glutathione to form glutathione and D-lactic acid.

1871111:DJ533 RS09315
gene id: 1871111:DJ533_RS09315
uniprot id: A0A2S2FD79
names: Similarity
messages: Belongs to the bacterial ring-hydroxylating dioxygenase beta subunit family.

1871111:DJ533 RS17380
gene id: 1871111:DJ533_RS17380
uniprot id: A0A2S2FGV7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

1871111:DJ533 RS17210
gene id: 1871111:DJ533_RS17210
uniprot id: A0A2S2FGT5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

1871111:DJ533 RS10280
gene id: 1871111:DJ533_RS10280
uniprot id: A0A2S2FDB0
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Component of the RNA degradosome, which is a multiprotein complex involved in RNA processing and mRNA degradation.
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

1871111:DJ533 RS07050
gene id: 1871111:DJ533_RS07050
uniprot id: A0A2S2FBK1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: In the N-terminal section; belongs to the FGAMS family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.

1871111:DJ533 RS12300
gene id: 1871111:DJ533_RS12300
uniprot id: A0A2S2FEA2
names: Similarity
messages: Belongs to the pirin family.

1871111:DJ533 RS17620
gene id: 1871111:DJ533_RS17620
uniprot id: A0A2S2FH20
names: Similarity
messages: Belongs to the acetyl-CoA hydrolase/transferase family.

1871111:DJ533 RS06330
gene id: 1871111:DJ533_RS06330
uniprot id: A0A2S2FB70
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1871111:DJ533 RS15045
gene id: 1871111:DJ533_RS15045
uniprot id: A0A2S2FHF0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

1871111:DJ533 RS09305
gene id: 1871111:DJ533_RS09305
uniprot id: A0A2S2FCQ6
names: Subcellular Location Annotation
messages: Membrane

1871111:DJ533 RS10945
gene id: 1871111:DJ533_RS10945
uniprot id: A0A2S2FDJ6
names: Similarity
messages: Belongs to the acylphosphatase family.

1871111:DJ533 RS00490
gene id: 1871111:DJ533_RS00490
uniprot id: A0A2S2FA46
names: Similarity
messages: Belongs to the MobA/MobL family.

1871111:DJ533 RS02180
gene id: 1871111:DJ533_RS02180
uniprot id: A0A2S2F910
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MerT family.
messages: Cell inner membrane
messages: Membrane

1871111:DJ533 RS05520
gene id: 1871111:DJ533_RS05520
uniprot id: A0A2S2FAT4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Cell membrane
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

1871111:DJ533 RS17850
gene id: 1871111:DJ533_RS17850
uniprot id: A0A2S2FIW2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1871111:DJ533 RS12950
gene id: 1871111:DJ533_RS12950
uniprot id: A0A2S2FEL7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1871111:DJ533 RS02565
gene id: 1871111:DJ533_RS02565
uniprot id: A0A2S2F9U7
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

1871111:DJ533 RS06320
gene id: 1871111:DJ533_RS06320
uniprot id: A0A2S2FB85
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 23 kDa subunit family.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1871111:DJ533 RS09270
gene id: 1871111:DJ533_RS09270
uniprot id: A0A2S2FCP4
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1871111:DJ533 RS08740
gene id: 1871111:DJ533_RS08740
uniprot id: A0A2S2FCE1
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1871111:DJ533 RS16340
gene id: 1871111:DJ533_RS16340
uniprot id: A0A2S2FGH7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I fumarase family.
messages: Catalyzes the reversible hydration of fumarate to (S)-malate.
messages: Homodimer.

1871111:DJ533 RS06460
gene id: 1871111:DJ533_RS06460
uniprot id: A0A2S2FB98
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.

1871111:DJ533 RS14170
gene id: 1871111:DJ533_RS14170
uniprot id: A0A2S2FF98
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

1871111:DJ533 RS18240
gene id: 1871111:DJ533_RS18240
uniprot id: A0A2S2FHW4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1871111:DJ533 RS12975
gene id: 1871111:DJ533_RS12975
uniprot id: A0A2S2FEN1
names: Similarity
messages: Belongs to the Nudix hydrolase family.

1871111:DJ533 RS18005
gene id: 1871111:DJ533_RS18005
uniprot id: A0A2S2FH69
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
messages: Cytoplasm
messages: Homotrimer.
messages: In the C-terminal section; belongs to the transferase hexapeptide repeat family.
messages: In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1871111:DJ533 RS16445
gene id: 1871111:DJ533_RS16445
uniprot id: A0A2S2FGL4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatB family.
messages: Cell membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

1871111:DJ533 RS14580
gene id: 1871111:DJ533_RS14580
uniprot id: A0A2S2FFI3
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1871111:DJ533 RS06715
gene id: 1871111:DJ533_RS06715
uniprot id: A0A2S2FBD7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 1 lipoyl cofactor covalently.
messages: E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).

1871111:DJ533 RS11285
gene id: 1871111:DJ533_RS11285
uniprot id: A0A2S2FDZ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

1871111:DJ533 RS15935
gene id: 1871111:DJ533_RS15935
uniprot id: A0A2S2FG74
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.

1871111:DJ533 RS03175
gene id: 1871111:DJ533_RS03175
uniprot id: A0A2S2F9L8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1871111:DJ533 RS08910
gene id: 1871111:DJ533_RS08910
uniprot id: A0A2S2FCP5
names: Function
names: Subcellular Location Annotation
messages: Catalyzes the Claisen rearrangement of chorismate to prephenate and the decarboxylation/dehydration of prephenate to phenylpyruvate.
messages: Cytoplasm

1871111:DJ533 RS14870
gene id: 1871111:DJ533_RS14870
uniprot id: A0A2S2FFL3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZipA family.
messages: Cell inner membrane
messages: Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins.

1871111:DJ533 RS16085
gene id: 1871111:DJ533_RS16085
uniprot id: A0A2S2FHZ2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecB family.
messages: Cytoplasm
messages: Homotetramer, a dimer of dimers. One homotetramer interacts with 1 SecA dimer.
messages: One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA.

1871111:DJ533 RS04975
gene id: 1871111:DJ533_RS04975
uniprot id: A0A2S2FAK1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

1871111:DJ533 RS03015
gene id: 1871111:DJ533_RS03015
uniprot id: A0A2S2FA15
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.
messages: Cell membrane
messages: Self-interacts. Interacts with FtsZ.

1871111:DJ533 RS16115
gene id: 1871111:DJ533_RS16115
uniprot id: A0A2S2FG93
names: Similarity
messages: Belongs to the UPF0758 family.

1871111:DJ533 RS15725
gene id: 1871111:DJ533_RS15725
uniprot id: A0A2S2FG86
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

1871111:DJ533 RS11875
gene id: 1871111:DJ533_RS11875
uniprot id: A0A2S2FE25
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

1871111:DJ533 RS15135
gene id: 1871111:DJ533_RS15135
uniprot id: A0A2S2FFV8
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

1871111:DJ533 RS18325
gene id: 1871111:DJ533_RS18325
uniprot id: A0A2S2FHJ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell membrane
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

1871111:DJ533 RS02470
gene id: 1871111:DJ533_RS02470
uniprot id: A0A2S2F8Y1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1871111:DJ533 RS09275
gene id: 1871111:DJ533_RS09275
uniprot id: A0A2S2FCP1
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1871111:DJ533 RS13695
gene id: 1871111:DJ533_RS13695
uniprot id: A0A2S2FF69
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1871111:DJ533 RS09045
gene id: 1871111:DJ533_RS09045
uniprot id: A0A2S2FCL6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsuA/YedE (TC 9.B.102) family.
messages: Cell inner membrane
messages: Membrane

1871111:DJ533 RS12240
gene id: 1871111:DJ533_RS12240
uniprot id: A0A2S2FEA5
names: Similarity
messages: Belongs to the glutathione peroxidase family.

1871111:DJ533 RS07425
gene id: 1871111:DJ533_RS07425
uniprot id: A0A2S2FBP8
names: Similarity
messages: Belongs to the aminoglycoside phosphotransferase family.

1871111:DJ533 RS06480
gene id: 1871111:DJ533_RS06480
uniprot id: A0A2S2FBA2
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dCTP deaminase family.
messages: Catalyzes the deamination of dCTP to dUTP.
messages: Homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1871111:DJ533 RS17420
gene id: 1871111:DJ533_RS17420
uniprot id: A0A2S2FH21
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

1871111:DJ533 RS05410
gene id: 1871111:DJ533_RS05410
uniprot id: A0A2S2FCN2
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

1871111:DJ533 RS07865
gene id: 1871111:DJ533_RS07865
uniprot id: A0A2S2FCG4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

1871111:DJ533 RS17545
gene id: 1871111:DJ533_RS17545
uniprot id: A0A2S2FGZ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic sulfate-binding protein family.
messages: Periplasm

1871111:DJ533 RS10025
gene id: 1871111:DJ533_RS10025
uniprot id: A0A2S2FDK7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

1871111:DJ533 RS04820
gene id: 1871111:DJ533_RS04820
uniprot id: A0A2S2FAN1
names: Similarity
messages: Belongs to the LOG family.

1871111:DJ533 RS18035
gene id: 1871111:DJ533_RS18035
uniprot id: A0A2S2FH82
names: Similarity
messages: Belongs to the UDPGP type 2 family.

1871111:DJ533 RS07555
gene id: 1871111:DJ533_RS07555
uniprot id: A0A2S2FHM1
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.

1871111:DJ533 RS07380
gene id: 1871111:DJ533_RS07380
uniprot id: A0A2S2FBY2
names: Similarity
messages: Belongs to the aminoglycoside phosphotransferase family.

1871111:DJ533 RS13180
gene id: 1871111:DJ533_RS13180
uniprot id: A0A2S2FEU1
names: Similarity
messages: Belongs to the long-chain O-acyltransferase family.

1871111:DJ533 RS06290
gene id: 1871111:DJ533_RS06290
uniprot id: A0A2S2FB71
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 20 kDa subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1871111:DJ533 RS13900
gene id: 1871111:DJ533_RS13900
uniprot id: A0A2S2FF64
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

1871111:DJ533 RS15580
gene id: 1871111:DJ533_RS15580
uniprot id: A0A2S2FFX8
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1871111:DJ533 RS06755
gene id: 1871111:DJ533_RS06755
uniprot id: A0A2S2FHL1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Bcr/CmlA family.
messages: Cell inner membrane
messages: Membrane

1871111:DJ533 RS09155
gene id: 1871111:DJ533_RS09155
uniprot id: A0A2S2FD47
names: Function
names: Similarity
names: Subunit
messages: Belongs to the trans-sulfuration enzymes family. MetZ subfamily.
messages: Catalyzes the formation of L-homocysteine from O-succinyl-L-homoserine (OSHS) and hydrogen sulfide.
messages: Homotetramer.

1871111:DJ533 RS06610
gene id: 1871111:DJ533_RS06610
uniprot id: A0A2S2FBC5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamD family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

1871111:DJ533 RS02685
gene id: 1871111:DJ533_RS02685
uniprot id: A0A2S2F9D8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1871111:DJ533 RS10770
gene id: 1871111:DJ533_RS10770
uniprot id: A0A2S2FDG3
names: Subcellular Location Annotation
messages: Membrane

1871111:DJ533 RS11525
gene id: 1871111:DJ533_RS11525
uniprot id: A0A2S2FDU6
names: Subcellular Location Annotation
messages: Membrane

1871111:DJ533 RS04250
gene id: 1871111:DJ533_RS04250
uniprot id: A0A2S2FAE4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ThiC family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
messages: Homodimer.

1871111:DJ533 RS02665
gene id: 1871111:DJ533_RS02665
uniprot id: A0A2S2F9G3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1871111:DJ533 RS05205
gene id: 1871111:DJ533_RS05205
uniprot id: A0A2S2FAQ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

1871111:DJ533 RS08780
gene id: 1871111:DJ533_RS08780
uniprot id: A0A2S2FCX7
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1871111:DJ533 RS07640
gene id: 1871111:DJ533_RS07640
uniprot id: A0A2S2FCC5
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

1871111:DJ533 RS18000
gene id: 1871111:DJ533_RS18000
uniprot id: A0A2S2FHD6
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG).

1871111:DJ533 RS07970
gene id: 1871111:DJ533_RS07970
uniprot id: A0A2S2FC06
names: Similarity
messages: Belongs to the aspartokinase family.

1871111:DJ533 RS05935
gene id: 1871111:DJ533_RS05935
uniprot id: A0A2S2FB65
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Membrane

1871111:DJ533 RS14455
gene id: 1871111:DJ533_RS14455
uniprot id: A0A2S2FFE3
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

1871111:DJ533 RS15655
gene id: 1871111:DJ533_RS15655
uniprot id: A0A2S2FG10
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

1871111:DJ533 RS02460
gene id: 1871111:DJ533_RS02460
uniprot id: A0A2S2F8Y7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1871111:DJ533 RS09235
gene id: 1871111:DJ533_RS09235
uniprot id: A0A2S2FCR7
names: Subcellular Location Annotation
messages: Membrane

1871111:DJ533 RS03510
gene id: 1871111:DJ533_RS03510
uniprot id: A0A2S2F9S6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1871111:DJ533 RS01655
gene id: 1871111:DJ533_RS01655
uniprot id: A0A2S2F982
names: Similarity
messages: Belongs to the SBNO family.

1871111:DJ533 RS09095
gene id: 1871111:DJ533_RS09095
uniprot id: A0A2S2FCM6
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.

1871111:DJ533 RS14295
gene id: 1871111:DJ533_RS14295
uniprot id: A0A2S2FID3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

1871111:DJ533 RS12770
gene id: 1871111:DJ533_RS12770
uniprot id: A0A2S2FF22
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.

1871111:DJ533 RS13460
gene id: 1871111:DJ533_RS13460
uniprot id: A0A2S2FFE2
names: Subcellular Location Annotation
messages: Membrane

1871111:DJ533 RS13680
gene id: 1871111:DJ533_RS13680
uniprot id: A0A2S2FFI1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the ABC transporter complex (TC 3.A.1.6.1) involved in sulfate/thiosulfate import.
messages: Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (CysA), two transmembrane proteins (CysT and CysW) and a solute-binding protein (CysP).

1871111:DJ533 RS15290
gene id: 1871111:DJ533_RS15290
uniprot id: A0A2S2FG13
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

1871111:DJ533 RS17335
gene id: 1871111:DJ533_RS17335
uniprot id: A0A2S2FGW9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

1871111:DJ533 RS08680
gene id: 1871111:DJ533_RS08680
uniprot id: A0A2S2FCD4
names: Subcellular Location Annotation
messages: Membrane

1871111:DJ533 RS03885
gene id: 1871111:DJ533_RS03885
uniprot id: A0A2S2FBV3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the heat shock protein 90 family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Molecular chaperone. Has ATPase activity.

1871111:DJ533 RS06955
gene id: 1871111:DJ533_RS06955
uniprot id: A0A2S2FBI5
names: Similarity
messages: Belongs to the peptidase S49 family.

1871111:DJ533 RS13290
gene id: 1871111:DJ533_RS13290
uniprot id: A0A2S2FEW3
names: Cofactor
messages: Can also use Mn(2+) ion.

1871111:DJ533 RS14955
gene id: 1871111:DJ533_RS14955
uniprot id: A0A2S2FFM3
names: Similarity
messages: Belongs to the YjdM family.

1871111:DJ533 RS12415
gene id: 1871111:DJ533_RS12415
uniprot id: A0A2S2FEI0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.
messages: Serves to protect the cell against DNA damage by alkyl hydroperoxides. It can use either NADH or NADPH as electron donor for direct reduction of redox dyes or of alkyl hydroperoxides when combined with the AhpC protein.

1871111:DJ533 RS06300
gene id: 1871111:DJ533_RS06300
uniprot id: A0A2S2FBN5
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

1871111:DJ533 RS17220
gene id: 1871111:DJ533_RS17220
uniprot id: A0A2S2FHB6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

1871111:DJ533 RS18500
gene id: 1871111:DJ533_RS18500
uniprot id: A0A2S2FHN5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm
messages: Purine salvage pathway enzyme which catalyzes the transfer of the ribosyl-5-phosphate group from 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to the N9 position of hypoxanthine to yield IMP (inosine 5'-monophosphate). To a lesser extent, can also act on guanine leading to GMP, but shows a highly less efficient activity with xanthine.

1871111:DJ533 RS04935
gene id: 1871111:DJ533_RS04935
uniprot id: A0A2S2FAJ2
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

1871111:DJ533 RS05160
gene id: 1871111:DJ533_RS05160
uniprot id: A0A2S2FAT3
names: Similarity
messages: Belongs to the FMO family.

1871111:DJ533 RS08530
gene id: 1871111:DJ533_RS08530
uniprot id: A0A2S2FE70
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxA subfamily.
messages: Cytoplasm
messages: Homotrimer.
messages: Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

1871111:DJ533 RS09845
gene id: 1871111:DJ533_RS09845
uniprot id: A0A2S2FD00
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1871111:DJ533 RS08480
gene id: 1871111:DJ533_RS08480
uniprot id: A0A2S2FE60
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Inhibited by UTP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1871111:DJ533 RS16375
gene id: 1871111:DJ533_RS16375
uniprot id: A0A2S2FGE3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

1871111:DJ533 RS10005
gene id: 1871111:DJ533_RS10005
uniprot id: A0A2S2FD28
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NlpA lipoprotein family.
messages: Membrane

1871111:DJ533 RS05220
gene id: 1871111:DJ533_RS05220
uniprot id: A0A2S2FCJ8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

1871111:DJ533 RS15495
gene id: 1871111:DJ533_RS15495
uniprot id: A0A2S2FGG0
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

1871111:DJ533 RS08355
gene id: 1871111:DJ533_RS08355
uniprot id: A0A2S2FCE8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1871111:DJ533 RS02015
gene id: 1871111:DJ533_RS02015
uniprot id: A0A2S2F985
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell outer membrane

1871111:DJ533 RS13585
gene id: 1871111:DJ533_RS13585
uniprot id: A0A2S2FIB8
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

1871111:DJ533 RS10190
gene id: 1871111:DJ533_RS10190
uniprot id: A0A2S2FD59
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

1871111:DJ533 RS08830
gene id: 1871111:DJ533_RS08830
uniprot id: A0A2S2FEB8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptA family.
messages: Component of the lipopolysaccharide transport and assembly complex.
messages: Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm.
messages: Periplasm

1871111:DJ533 RS08965
gene id: 1871111:DJ533_RS08965
uniprot id: A0A2S2FCQ5
names: Similarity
messages: Belongs to the HMG-CoA lyase family.

1871111:DJ533 RS15995
gene id: 1871111:DJ533_RS15995
uniprot id: A0A2S2FG73
names: Similarity
messages: Belongs to the GppA/Ppx family.

1871111:DJ533 RS08475
gene id: 1871111:DJ533_RS08475
uniprot id: A0A2S2FC98
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methylthiotransferase family. RimO subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein uS12.
messages: Cytoplasm

1871111:DJ533 RS18115
gene id: 1871111:DJ533_RS18115
uniprot id: A0A2S2FJ11
names: Similarity
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.

1871111:DJ533 RS17455
gene id: 1871111:DJ533_RS17455
uniprot id: A0A2S2FHF5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PPase family.
messages: Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
messages: Cytoplasm
messages: Homohexamer.

1871111:DJ533 RS10955
gene id: 1871111:DJ533_RS10955
uniprot id: A0A2S2FHW1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueG family.
messages: Binds 2 [4Fe-4S] clusters per monomer.
messages: Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1871111:DJ533 RS04535
gene id: 1871111:DJ533_RS04535
uniprot id: A0A2S2FAT2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Membrane

1871111:DJ533 RS08785
gene id: 1871111:DJ533_RS08785
uniprot id: A0A2S2FCF3
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1871111:DJ533 RS05365
gene id: 1871111:DJ533_RS05365
uniprot id: A0A2S2FAR7
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1871111:DJ533 RS07325
gene id: 1871111:DJ533_RS07325
uniprot id: A0A2S2FBX2
names: Similarity
messages: Belongs to the transcriptional regulatory Fis family.

1871111:DJ533 RS02690
gene id: 1871111:DJ533_RS02690
uniprot id: A0A2S2F9E5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1871111:DJ533 RS17700
gene id: 1871111:DJ533_RS17700
uniprot id: A0A2S2FH91
names: Similarity
messages: Belongs to the pseudomonas-type ThrB family.

1871111:DJ533 RS15340
gene id: 1871111:DJ533_RS15340
uniprot id: A0A2S2FG23
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HemJ family.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.
messages: Catalyzes the oxidation of protoporphyrinogen IX to protoporphyrin IX.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

1871111:DJ533 RS15640
gene id: 1871111:DJ533_RS15640
uniprot id: A0A2S2FG04
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell outer membrane

1871111:DJ533 RS06965
gene id: 1871111:DJ533_RS06965
uniprot id: A0A2S2FBG8
names: Function
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
messages: Catalyzes two reactions in de novo purine nucleotide biosynthesis. Catalyzes the breakdown of 5-aminoimidazole- (N-succinylocarboxamide) ribotide (SAICAR or 2-[5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamido]succinate) to 5-aminoimidazole-4-carboxamide ribotide (AICAR or 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide) and fumarate, and of adenylosuccinate (ADS or N(6)-(1,2-dicarboxyethyl)-AMP) to adenosine monophosphate (AMP) and fumarate.

1871111:DJ533 RS07525
gene id: 1871111:DJ533_RS07525
uniprot id: A0A2S2FBT3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. Lipoprotein translocase (TC 3.A.1.125) family.
messages: Cell inner membrane
messages: Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner.
messages: The complex is composed of two ATP-binding proteins (LolD) and two transmembrane proteins (LolC and LolE).

1871111:DJ533 RS13150
gene id: 1871111:DJ533_RS13150
uniprot id: A0A2S2FEX0
names: Subcellular Location Annotation
messages: Membrane

1871111:DJ533 RS09285
gene id: 1871111:DJ533_RS09285
uniprot id: A0A2S2FCS7
names: Similarity
messages: Belongs to the peptidase S66 family.

1871111:DJ533 RS07350
gene id: 1871111:DJ533_RS07350
uniprot id: A0A2S2FDL7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

1871111:DJ533 RS16920
gene id: 1871111:DJ533_RS16920
uniprot id: A0A2S2FGP6
names: Similarity
messages: Belongs to the 4-hydroxy-2-oxovalerate aldolase family.

1871111:DJ533 RS01385
gene id: 1871111:DJ533_RS01385
uniprot id: A0A2S2F8H4
names: Function
names: Similarity
messages: Absolutely required for transposition of IS1.
messages: Belongs to the transposase 27 family.

1871111:DJ533 RS04770
gene id: 1871111:DJ533_RS04770
uniprot id: A0A2S2FAM6
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

1871111:DJ533 RS06140
gene id: 1871111:DJ533_RS06140
uniprot id: A0A2S2FB56
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1871111:DJ533 RS14190
gene id: 1871111:DJ533_RS14190
uniprot id: A0A2S2FF93
names: Function
names: Similarity
messages: Belongs to the UPF0677 family.
messages: Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity.

1871111:DJ533 RS16985
gene id: 1871111:DJ533_RS16985
uniprot id: A0A2S2FGP7
names: Subcellular Location Annotation
messages: Membrane

1871111:DJ533 RS13060
gene id: 1871111:DJ533_RS13060
uniprot id: A0A2S2FGJ1
names: Similarity
messages: Belongs to the band 7/mec-2 family. Flotillin subfamily.

1871111:DJ533 RS06560
gene id: 1871111:DJ533_RS06560
uniprot id: A0A2S2FBI9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

1871111:DJ533 RS17735
gene id: 1871111:DJ533_RS17735
uniprot id: A0A2S2FHL2
names: Similarity
messages: Belongs to the nucleoside-specific channel-forming outer membrane porin (Tsx) (TC 1.B.10) family.

1871111:DJ533 RS02310
gene id: 1871111:DJ533_RS02310
uniprot id: A0A2S2F8Y6
names: Similarity
messages: Belongs to the extradiol ring-cleavage dioxygenase family.

1871111:DJ533 RS17525
gene id: 1871111:DJ533_RS17525
uniprot id: A0A2S2FH44
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsL family.
messages: Cell inner membrane
messages: Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.
messages: Membrane
messages: Part of a complex composed of FtsB, FtsL and FtsQ.

1871111:DJ533 RS01985
gene id: 1871111:DJ533_RS01985
uniprot id: A0A2S2F9K2
names: Similarity
messages: Belongs to the site-specific recombinase resolvase family.

1871111:DJ533 RS04765
gene id: 1871111:DJ533_RS04765
uniprot id: A0A2S2FAG8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

1871111:DJ533 RS13190
gene id: 1871111:DJ533_RS13190
uniprot id: A0A2S2FES2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YhdE subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

1871111:DJ533 RS12310
gene id: 1871111:DJ533_RS12310
uniprot id: A0A2S2FEG1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1871111:DJ533 RS04940
gene id: 1871111:DJ533_RS04940
uniprot id: A0A2S2FAP1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

1871111:DJ533 RS16365
gene id: 1871111:DJ533_RS16365
uniprot id: A0A2S2FGF6
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

1871111:DJ533 RS06980
gene id: 1871111:DJ533_RS06980
uniprot id: A0A2S2FBK2
names: Similarity
names: Subunit
messages: Belongs to the Nudix hydrolase family. NudJ subfamily.
messages: Monomer.

1871111:DJ533 RS17980
gene id: 1871111:DJ533_RS17980
uniprot id: A0A2S2FH78
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DHBP synthase family.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Homodimer.
messages: In the C-terminal section; belongs to the GTP cyclohydrolase II family.
messages: In the N-terminal section; belongs to the DHBP synthase family.

1871111:DJ533 RS15255
gene id: 1871111:DJ533_RS15255
uniprot id: A0A2S2FFR8
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

1871111:DJ533 RS09425
gene id: 1871111:DJ533_RS09425
uniprot id: A0A2S2FCS2
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.
messages: There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors.

1871111:DJ533 RS14315
gene id: 1871111:DJ533_RS14315
uniprot id: A0A2S2FHT4
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1871111:DJ533 RS11470
gene id: 1871111:DJ533_RS11470
uniprot id: A0A2S2FFP5
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.

1871111:DJ533 RS06015
gene id: 1871111:DJ533_RS06015
uniprot id: A0A2S2FB14
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OmpP1/FadL family.
messages: Cell outer membrane
messages: Membrane

1871111:DJ533 RS02640
gene id: 1871111:DJ533_RS02640
uniprot id: A0A2S2F9D7
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

1871111:DJ533 RS18545
gene id: 1871111:DJ533_RS18545
uniprot id: A0A2S2FHH5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Cell membrane
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

1871111:DJ533 RS18150
gene id: 1871111:DJ533_RS18150
uniprot id: A0A2S2FHF4
names: Function
names: Similarity
messages: Belongs to the NadC/ModD family.
messages: Involved in the catabolism of quinolinic acid (QA).

1871111:DJ533 RS09195
gene id: 1871111:DJ533_RS09195
uniprot id: A0A2S2FCM9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

1871111:DJ533 RS01080
gene id: 1871111:DJ533_RS01080
uniprot id: A0A2S2F8M4
names: Function
names: Similarity
messages: Belongs to the DHPS family.
messages: Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives.

1871111:DJ533 RS03650
gene id: 1871111:DJ533_RS03650
uniprot id: A0A2S2F9W4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1871111:DJ533 RS14360
gene id: 1871111:DJ533_RS14360
uniprot id: A0A2S2FFC6
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1871111:DJ533 RS11725
gene id: 1871111:DJ533_RS11725
uniprot id: A0A2S2FHT5
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1871111:DJ533 RS10345
gene id: 1871111:DJ533_RS10345
uniprot id: A0A2S2FDH4
names: Subcellular Location Annotation
messages: Membrane

1871111:DJ533 RS18010
gene id: 1871111:DJ533_RS18010
uniprot id: A0A2S2FIZ3
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

1871111:DJ533 RS07760
gene id: 1871111:DJ533_RS07760
uniprot id: A0A2S2FC46
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).

1871111:DJ533 RS14690
gene id: 1871111:DJ533_RS14690
uniprot id: A0A2S2FFJ3
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1871111:DJ533 RS02500
gene id: 1871111:DJ533_RS02500
uniprot id: A0A2S2F9B9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

1871111:DJ533 RS06580
gene id: 1871111:DJ533_RS06580
uniprot id: A0A2S2FBC4
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.

1871111:DJ533 RS13895
gene id: 1871111:DJ533_RS13895
uniprot id: A0A2S2FF36
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

1871111:DJ533 RS18190
gene id: 1871111:DJ533_RS18190
uniprot id: A0A2S2FHB7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbA subfamily.
messages: Periplasm

1871111:DJ533 RS15515
gene id: 1871111:DJ533_RS15515
uniprot id: A0A2S2FG52
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

1871111:DJ533 RS16120
gene id: 1871111:DJ533_RS16120
uniprot id: A0A2S2FG80
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anion channel-forming bestrophin (TC 1.A.46) family.
messages: Membrane

1871111:DJ533 RS12960
gene id: 1871111:DJ533_RS12960
uniprot id: A0A2S2FEN0
names: Similarity
messages: Belongs to the transglycosylase Slt family.

1871111:DJ533 RS10780
gene id: 1871111:DJ533_RS10780
uniprot id: A0A2S2FDK0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Aromatic acid:H(+) symporter (AAHS) (TC 2.A.1.15) family.
messages: Membrane

1871111:DJ533 RS07440
gene id: 1871111:DJ533_RS07440
uniprot id: A0A2S2FBZ1
names: Similarity
messages: Belongs to the site-specific recombinase resolvase family.

1871111:DJ533 RS16600
gene id: 1871111:DJ533_RS16600
uniprot id: A0A2S2FGP3
names: Similarity
messages: Belongs to the glycerate kinase type-1 family.

1871111:DJ533 RS13630
gene id: 1871111:DJ533_RS13630
uniprot id: A0A2S2FEZ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 51 family.
messages: Cell inner membrane
messages: Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors.

1871111:DJ533 RS02225
gene id: 1871111:DJ533_RS02225
uniprot id: A0A2S2F919
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MerT family.
messages: Cell inner membrane
messages: Membrane

1871111:DJ533 RS17655
gene id: 1871111:DJ533_RS17655
uniprot id: A0A2S2FH08
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

1871111:DJ533 RS12775
gene id: 1871111:DJ533_RS12775
uniprot id: A0A2S2FEJ7
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

1871111:DJ533 RS13440
gene id: 1871111:DJ533_RS13440
uniprot id: A0A2S2FEW2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

1871111:DJ533 RS14855
gene id: 1871111:DJ533_RS14855
uniprot id: A0A2S2FFT1
names: Function
names: Similarity
messages: Belongs to the bacterioferritin family.
messages: Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex.

1871111:DJ533 RS14480
gene id: 1871111:DJ533_RS14480
uniprot id: A0A2S2FFE6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

1871111:DJ533 RS11235
gene id: 1871111:DJ533_RS11235
uniprot id: A0A2S2FDQ3
names: Subcellular Location Annotation
messages: Membrane

1871111:DJ533 RS13980
gene id: 1871111:DJ533_RS13980
uniprot id: A0A2S2FF57
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1871111:DJ533 RS15535
gene id: 1871111:DJ533_RS15535
uniprot id: A0A2S2FHN7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

1871111:DJ533 RS03185
gene id: 1871111:DJ533_RS03185
uniprot id: A0A2S2F9W1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1871111:DJ533 RS06255
gene id: 1871111:DJ533_RS06255
uniprot id: A0A2S2FB55
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.

1871111:DJ533 RS12845
gene id: 1871111:DJ533_RS12845
uniprot id: A0A2S2FES1
names: Similarity
messages: To bacterial alkanal monooxygenase alpha and beta chains.

1871111:DJ533 RS18125
gene id: 1871111:DJ533_RS18125
uniprot id: A0A2S2FHB9
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

1871111:DJ533 RS07010
gene id: 1871111:DJ533_RS07010
uniprot id: A0A2S2FC13
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

1871111:DJ533 RS17795
gene id: 1871111:DJ533_RS17795
uniprot id: A0A2S2FH38
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family. ParE type 1 subfamily.
messages: Heterotetramer composed of ParC and ParE.
messages: Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.

1871111:DJ533 RS08770
gene id: 1871111:DJ533_RS08770
uniprot id: A0A2S2FCF9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1871111:DJ533 RS08520
gene id: 1871111:DJ533_RS08520
uniprot id: A0A2S2FCJ0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
messages: Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
messages: Homotrimer.

1871111:DJ533 RS05625
gene id: 1871111:DJ533_RS05625
uniprot id: A0A2S2FAV4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homodimer.

1871111:DJ533 RS02765
gene id: 1871111:DJ533_RS02765
uniprot id: A0A2S2F9H7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0391 family.
messages: Cell membrane

1871111:DJ533 RS08325
gene id: 1871111:DJ533_RS08325
uniprot id: A0A2S2FE30
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm

1871111:DJ533 RS00665
gene id: 1871111:DJ533_RS00665
uniprot id: A0A2S2F8V5
names: Similarity
messages: Belongs to the type IA topoisomerase family.

1871111:DJ533 RS03560
gene id: 1871111:DJ533_RS03560
uniprot id: A0A2S2F9T6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

1871111:DJ533 RS04605
gene id: 1871111:DJ533_RS04605
uniprot id: A0A2S2FAD2
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

1871111:DJ533 RS08790
gene id: 1871111:DJ533_RS08790
uniprot id: A0A2S2FCF1
names: Similarity
messages: Belongs to the acetyl-CoA hydrolase/transferase family.

1871111:DJ533 RS06365
gene id: 1871111:DJ533_RS06365
uniprot id: A0A2S2FB82
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1871111:DJ533 RS16320
gene id: 1871111:DJ533_RS16320
uniprot id: A0A2S2FGV5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Mg(2+). Can also accept Mn(2+).

1871111:DJ533 RS13720
gene id: 1871111:DJ533_RS13720
uniprot id: A0A2S2FGV3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the QueC family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).

1871111:DJ533 RS17540
gene id: 1871111:DJ533_RS17540
uniprot id: A0A2S2FIR2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic sulfate-binding protein family.
messages: Periplasm

1871111:DJ533 RS15225
gene id: 1871111:DJ533_RS15225
uniprot id: A0A2S2FIE1
names: Function
names: Similarity
names: Subunit
messages: ATPase required for the correct placement of the division site. Cell division inhibitors MinC and MinD act in concert to form an inhibitor capable of blocking formation of the polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings.
messages: Belongs to the ParA family. MinD subfamily.
messages: Interacts with MinC and FtsZ.

1871111:DJ533 RS04965
gene id: 1871111:DJ533_RS04965
uniprot id: A0A2S2FB10
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

1871111:DJ533 RS11245
gene id: 1871111:DJ533_RS11245
uniprot id: A0A2S2FE75
names: Similarity
messages: Belongs to the peptidase M16 family.

1871111:DJ533 RS00500
gene id: 1871111:DJ533_RS00500
uniprot id: A0A2S2F899
names: Similarity
messages: Belongs to the YoeB family.

1871111:DJ533 RS02505
gene id: 1871111:DJ533_RS02505
uniprot id: A0A2S2F9T8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

1871111:DJ533 RS16380
gene id: 1871111:DJ533_RS16380
uniprot id: A0A2S2FGD0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1871111:DJ533 RS12390
gene id: 1871111:DJ533_RS12390
uniprot id: A0A2S2FEB9
names: Subcellular Location Annotation
messages: Membrane

1871111:DJ533 RS16405
gene id: 1871111:DJ533_RS16405
uniprot id: A0A2S2FI56
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Cytoplasm
messages: Homodimer.

1871111:DJ533 RS15365
gene id: 1871111:DJ533_RS15365
uniprot id: A0A2S2FHK7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscL family.
messages: Cell inner membrane
messages: Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
messages: Homopentamer.
messages: Membrane

1871111:DJ533 RS15730
gene id: 1871111:DJ533_RS15730
uniprot id: A0A2S2FG09
names: Function
names: Similarity
messages: Belongs to the HPPK family.
messages: Catalyzes the transfer of pyrophosphate from adenosine triphosphate (ATP) to 6-hydroxymethyl-7,8-dihydropterin, an enzymatic step in folate biosynthesis pathway.

1871111:DJ533 RS08085
gene id: 1871111:DJ533_RS08085
uniprot id: A0A2S2FC16
names: Similarity
messages: Belongs to the peptidase S16 family.

1871111:DJ533 RS16670
gene id: 1871111:DJ533_RS16670
uniprot id: A0A2S2FGH8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LpxL/LpxM/LpxP family.
messages: Catalyzes the transfer of an acyl chain from an acyl-[acyl-carrier-protein] (ACP) to a Kdo(2)-lipid IV(A) to form a Kdo(2)-(acyl)-lipid IV(A).
messages: Cell inner membrane

1871111:DJ533 RS17705
gene id: 1871111:DJ533_RS17705
uniprot id: A0A2S2FH76
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

1871111:DJ533 RS13800
gene id: 1871111:DJ533_RS13800
uniprot id: A0A2S2FFK0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoD/SigA subfamily.
messages: Cytoplasm
messages: Interacts transiently with the RNA polymerase catalytic core.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.

1871111:DJ533 RS12445
gene id: 1871111:DJ533_RS12445
uniprot id: A0A2S2FEF4
names: Similarity
messages: Belongs to the DinB family.

1871111:DJ533 RS06950
gene id: 1871111:DJ533_RS06950
uniprot id: A0A2S2FBI2
names: Similarity
messages: Belongs to the glutaredoxin family. Monothiol subfamily.

1871111:DJ533 RS13625
gene id: 1871111:DJ533_RS13625
uniprot id: A0A2S2FFH0
names: Function
names: PTM
names: Similarity
messages: An intermediate of this reaction is the autophosphorylated ppk in which a phosphate is covalently linked to a histidine residue through a N-P bond.
messages: Belongs to the polyphosphate kinase 1 (PPK1) family.
messages: Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP).

1871111:DJ533 RS17295
gene id: 1871111:DJ533_RS17295
uniprot id: A0A2S2FH13
names: Function
names: Similarity
messages: Belongs to the bacterioferritin family.
messages: Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex.

1871111:DJ533 RS07610
gene id: 1871111:DJ533_RS07610
uniprot id: A0A2S2FBW8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Cytochrome bo(3) ubiquinol terminal oxidase is the component of the aerobic respiratory chain of E.coli that predominates when cells are grown at high aeration. Has proton pump activity across the membrane in addition to electron transfer, pumping 2 protons/electron.
messages: Heterooctamer of two A chains, two B chains, two C chains and two D chains.
messages: Membrane

1871111:DJ533 RS05940
gene id: 1871111:DJ533_RS05940
uniprot id: A0A2S2FB06
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

1871111:DJ533 RS16390
gene id: 1871111:DJ533_RS16390
uniprot id: A0A2S2FGI6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1871111:DJ533 RS14760
gene id: 1871111:DJ533_RS14760
uniprot id: A0A2S2FFN9
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

1871111:DJ533 RS05555
gene id: 1871111:DJ533_RS05555
uniprot id: A0A2S2FAT5
names: Function
names: Similarity
messages: Belongs to the GlnE family.
messages: Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell.

1871111:DJ533 RS11060
gene id: 1871111:DJ533_RS11060
uniprot id: A0A2S2FHP9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Reduced FMN (FMNH(2)).

1871111:DJ533 RS07190
gene id: 1871111:DJ533_RS07190
uniprot id: A0A2S2FBL7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

1871111:DJ533 RS09795
gene id: 1871111:DJ533_RS09795
uniprot id: A0A2S2FCZ2
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1871111:DJ533 RS05460
gene id: 1871111:DJ533_RS05460
uniprot id: A0A2S2FCP2
names: Similarity
messages: Belongs to the Cob(I)alamin adenosyltransferase family.

1871111:DJ533 RS18315
gene id: 1871111:DJ533_RS18315
uniprot id: A0A2S2FHK8
names: Function
names: Similarity
messages: Belongs to the ribF family.
messages: Catalyzes the phosphorylation of riboflavin to FMN followed by the adenylation of FMN to FAD.

1871111:DJ533 RS03570
gene id: 1871111:DJ533_RS03570
uniprot id: A0A2S2FA29
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

1871111:DJ533 RS07135
gene id: 1871111:DJ533_RS07135
uniprot id: A0A2S2FBK9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

1871111:DJ533 RS16730
gene id: 1871111:DJ533_RS16730
uniprot id: A0A2S2FGR4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

1871111:DJ533 RS11770
gene id: 1871111:DJ533_RS11770
uniprot id: A0A2S2FDZ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

1871111:DJ533 RS13220
gene id: 1871111:DJ533_RS13220
uniprot id: A0A2S2FGM0
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

1871111:DJ533 RS05005
gene id: 1871111:DJ533_RS05005
uniprot id: A0A2S2FAJ4
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

1871111:DJ533 RS09360
gene id: 1871111:DJ533_RS09360
uniprot id: A0A2S2FCT0
names: Function
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

1871111:DJ533 RS15795
gene id: 1871111:DJ533_RS15795
uniprot id: A0A2S2FG34
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein uL14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein uL14 (rplN).

1871111:DJ533 RS08630
gene id: 1871111:DJ533_RS08630
uniprot id: A0A2S2FCC2
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.
messages: This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.

1871111:DJ533 RS03530
gene id: 1871111:DJ533_RS03530
uniprot id: A0A2S2F9Z2
names: Subcellular Location Annotation
messages: Membrane

1871111:DJ533 RS00430
gene id: 1871111:DJ533_RS00430
uniprot id: A0A2S2F881
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

1871111:DJ533 RS11020
gene id: 1871111:DJ533_RS11020
uniprot id: A0A2S2FDL2
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

1871111:DJ533 RS10415
gene id: 1871111:DJ533_RS10415
uniprot id: A0A2S2FDI3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1871111:DJ533 RS08425
gene id: 1871111:DJ533_RS08425
uniprot id: A0A2S2FE50
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

1871111:DJ533 RS14425
gene id: 1871111:DJ533_RS14425
uniprot id: A0A2S2FFX0
names: Similarity
messages: Belongs to the pirin family.

1871111:DJ533 RS05185
gene id: 1871111:DJ533_RS05185
uniprot id: A0A2S2FB48
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

1871111:DJ533 RS06315
gene id: 1871111:DJ533_RS06315
uniprot id: A0A2S2FBE8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 1 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.

1871111:DJ533 RS13340
gene id: 1871111:DJ533_RS13340
uniprot id: A0A2S2FEX3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the quinone-dependent D-lactate dehydrogenase family.
messages: Catalyzes the oxidation of D-lactate to pyruvate.
messages: Cell inner membrane

1871111:DJ533 RS08865
gene id: 1871111:DJ533_RS08865
uniprot id: A0A2S2FCJ7
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

1871111:DJ533 RS07415
gene id: 1871111:DJ533_RS07415
uniprot id: A0A2S2FBR9
names: Function
messages: Involved in the transposition of the insertion sequence.

1871111:DJ533 RS02535
gene id: 1871111:DJ533_RS02535
uniprot id: A0A2S2F9E3
names: Function
names: Similarity
messages: Belongs to the anhydro-N-acetylmuramic acid kinase family.
messages: Catalyzes the specific phosphorylation of 1,6-anhydro-N-acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling.

1871111:DJ533 RS10805
gene id: 1871111:DJ533_RS10805
uniprot id: A0A2S2FDI8
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1871111:DJ533 RS07260
gene id: 1871111:DJ533_RS07260
uniprot id: A0A2S2FBM1
names: Similarity
messages: In the N-terminal section; belongs to the NADH:flavin oxidoreductase/NADH oxidase family.

1871111:DJ533 RS14740
gene id: 1871111:DJ533_RS14740
uniprot id: A0A2S2FG18
names: Function
names: Similarity
messages: Belongs to the DUF177 domain family.
messages: Plays a role in synthesis, processing and/or stability of 23S rRNA.

1871111:DJ533 RS14290
gene id: 1871111:DJ533_RS14290
uniprot id: A0A2S2FFH9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

1871111:DJ533 RS09615
gene id: 1871111:DJ533_RS09615
uniprot id: A0A2S2FCV8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAD-like hydrolase superfamily. PhnX family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Involved in phosphonate degradation.

1871111:DJ533 RS11795
gene id: 1871111:DJ533_RS11795
uniprot id: A0A2S2FDZ5
names: Subcellular Location Annotation
messages: Membrane

1871111:DJ533 RS04215
gene id: 1871111:DJ533_RS04215
uniprot id: A0A2S2FC12
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

1871111:DJ533 RS15380
gene id: 1871111:DJ533_RS15380
uniprot id: A0A2S2FGD9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methyltransferase superfamily. RsmC family.
messages: Cytoplasm
messages: Monomer.
messages: Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle.

1871111:DJ533 RS03615
gene id: 1871111:DJ533_RS03615
uniprot id: A0A2S2F9X6
names: Function
names: Similarity
messages: Belongs to the TenA family.
messages: Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway.

1871111:DJ533 RS11825
gene id: 1871111:DJ533_RS11825
uniprot id: A0A2S2FE14
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit A family.

1871111:DJ533 RS04925
gene id: 1871111:DJ533_RS04925
uniprot id: A0A2S2FAJ1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

1871111:DJ533 RS16900
gene id: 1871111:DJ533_RS16900
uniprot id: A0A2S2FIE5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1871111:DJ533 RS15845
gene id: 1871111:DJ533_RS15845
uniprot id: A0A2S2FHV0
names: Subcellular Location Annotation
messages: Membrane

1871111:DJ533 RS03675
gene id: 1871111:DJ533_RS03675
uniprot id: A0A2S2F9Y0
names: Similarity
messages: Belongs to the Gfa family.

1871111:DJ533 RS06650
gene id: 1871111:DJ533_RS06650
uniprot id: A0A2S2FBB8
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
messages: In the C-terminal section; belongs to the NAD synthetase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1871111:DJ533 RS03965
gene id: 1871111:DJ533_RS03965
uniprot id: A0A2S2FA41
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

1871111:DJ533 RS09080
gene id: 1871111:DJ533_RS09080
uniprot id: A0A2S2FCL1
names: Subcellular Location Annotation
messages: Membrane

1871111:DJ533 RS06545
gene id: 1871111:DJ533_RS06545
uniprot id: A0A2S2FBA1
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanD family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
messages: Cytoplasm
messages: Heterooctamer of four alpha and four beta subunits.
messages: Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus.

1871111:DJ533 RS07080
gene id: 1871111:DJ533_RS07080
uniprot id: A0A2S2FBM3
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1871111:DJ533 RS14275
gene id: 1871111:DJ533_RS14275
uniprot id: A0A2S2FFB6
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1871111:DJ533 RS05480
gene id: 1871111:DJ533_RS05480
uniprot id: A0A2S2FB95
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

1871111:DJ533 RS16545
gene id: 1871111:DJ533_RS16545
uniprot id: A0A2S2FGN3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

1871111:DJ533 RS11025
gene id: 1871111:DJ533_RS11025
uniprot id: A0A2S2FDN0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LpxH family.
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.
messages: Binds 2 Mn(2+) ions per subunit in a binuclear metal center.
messages: Cell inner membrane
messages: Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

1871111:DJ533 RS06765
gene id: 1871111:DJ533_RS06765
uniprot id: A0A2S2FBL6
names: Domain
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 dependent methionine synthase family.
messages: Catalyzes the transfer of a methyl group from methyl-cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
messages: Modular enzyme with four functionally distinct domains. The isolated Hcy-binding domain catalyzes methyl transfer from free methylcobalamin to homocysteine. The Hcy-binding domain in association with the pterin-binding domain catalyzes the methylation of cob(I)alamin by methyltetrahydrofolate and the methylation of homocysteine. The B12-binding domain binds the cofactor. The AdoMet activation domain binds S-adenosyl-L-methionine. Under aerobic conditions cob(I)alamin can be converted to inactive cob(II)alamin. Reductive methylation by S-adenosyl-L-methionine and flavodoxin regenerates methylcobalamin.

1871111:DJ533 RS06135
gene id: 1871111:DJ533_RS06135
uniprot id: A0A2S2FBC1
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1871111:DJ533 RS05990
gene id: 1871111:DJ533_RS05990
uniprot id: A0A2S2FB15
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

1871111:DJ533 RS09980
gene id: 1871111:DJ533_RS09980
uniprot id: A0A2S2FD22
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arsenical resistance-3 (ACR3) (TC 2.A.59) family.
messages: Cell membrane
messages: Membrane

1871111:DJ533 RS18345
gene id: 1871111:DJ533_RS18345
uniprot id: A0A2S2FHG4
names: Subcellular Location Annotation
messages: Membrane

1871111:DJ533 RS11760
gene id: 1871111:DJ533_RS11760
uniprot id: A0A2S2FE16
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP L family.
messages: Cell inner membrane
messages: Inner membrane component of the type II secretion system required for the energy-dependent secretion of extracellular factors such as proteases and toxins from the periplasm.
messages: Membrane

1871111:DJ533 RS17910
gene id: 1871111:DJ533_RS17910
uniprot id: A0A2S2FIX4
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1871111:DJ533 RS07270
gene id: 1871111:DJ533_RS07270
uniprot id: A0A2S2FBW3
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

1871111:DJ533 RS09630
gene id: 1871111:DJ533_RS09630
uniprot id: A0A2S2FCW3
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1871111:DJ533 RS18515
gene id: 1871111:DJ533_RS18515
uniprot id: A0A2S2FHZ6
names: Subcellular Location Annotation
messages: Membrane

1871111:DJ533 RS15400
gene id: 1871111:DJ533_RS15400
uniprot id: A0A2S2FG05
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

1871111:DJ533 RS07995
gene id: 1871111:DJ533_RS07995
uniprot id: A0A2S2FC82
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1871111:DJ533 RS09830
gene id: 1871111:DJ533_RS09830
uniprot id: A0A2S2FD35
names: Similarity
messages: Belongs to the HipA Ser/Thr kinase family.

1871111:DJ533 RS13095
gene id: 1871111:DJ533_RS13095
uniprot id: A0A2S2FEV9
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

1871111:DJ533 RS14320
gene id: 1871111:DJ533_RS14320
uniprot id: A0A2S2FFV0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate:Na(+) symporter (ESS) (TC 2.A.27) family.
messages: Catalyzes the sodium-dependent transport of glutamate.
messages: Cell inner membrane

1871111:DJ533 RS08335
gene id: 1871111:DJ533_RS08335
uniprot id: A0A2S2FC81
names: Function
names: Similarity
names: Subunit
messages: Belongs to the isocitrate lyase/PEP mutase superfamily. Methylisocitrate lyase family.
messages: Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate.
messages: Homotetramer; dimer of dimers.
messages: Involved in the catabolism of short chain fatty acids (SCFA) via the 2-methylcitrate cycle (propionate degradation route). Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate via an alpha-carboxy-carbanion intermediate.

1871111:DJ533 RS17860
gene id: 1871111:DJ533_RS17860
uniprot id: A0A2S2FH67
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

1871111:DJ533 RS17120
gene id: 1871111:DJ533_RS17120
uniprot id: A0A2S2FGR3
names: Subcellular Location Annotation
messages: Membrane

1871111:DJ533 RS03550
gene id: 1871111:DJ533_RS03550
uniprot id: A0A2S2F9U4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase delta chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

1871111:DJ533 RS02020
gene id: 1871111:DJ533_RS02020
uniprot id: A0A2S2F955
names: Subcellular Location Annotation
messages: Membrane

1871111:DJ533 RS09160
gene id: 1871111:DJ533_RS09160
uniprot id: A0A2S2FCM4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

1871111:DJ533 RS11695
gene id: 1871111:DJ533_RS11695
uniprot id: A0A2S2FEE9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecX family.
messages: Cytoplasm
messages: Modulates RecA activity.

1871111:DJ533 RS08975
gene id: 1871111:DJ533_RS08975
uniprot id: A0A2S2FCS4
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1871111:DJ533 RS08270
gene id: 1871111:DJ533_RS08270
uniprot id: A0A2S2FC60
names: Similarity
messages: Belongs to the GSP E family.

1871111:DJ533 RS14485
gene id: 1871111:DJ533_RS14485
uniprot id: A0A2S2FHU3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

1871111:DJ533 RS08800
gene id: 1871111:DJ533_RS08800
uniprot id: A0A2S2FCM5
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

1871111:DJ533 RS09330
gene id: 1871111:DJ533_RS09330
uniprot id: A0A2S2FCX5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Also exhibits azoreductase activity. Catalyzes the reductive cleavage of the azo bond in aromatic azo compounds to the corresponding amines.
messages: Belongs to the azoreductase type 1 family.
messages: Binds 1 FMN per subunit.
messages: Homodimer.
messages: Quinone reductase that provides resistance to thiol-specific stress caused by electrophilic quinones.

1871111:DJ533 RS09560
gene id: 1871111:DJ533_RS09560
uniprot id: A0A2S2FD39
names: Similarity
messages: Belongs to the glutamate synthase family.

1871111:DJ533 RS15635
gene id: 1871111:DJ533_RS15635
uniprot id: A0A2S2FHQ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

1871111:DJ533 RS18525
gene id: 1871111:DJ533_RS18525
uniprot id: A0A2S2FJ87
names: Subcellular Location Annotation
messages: Membrane

1871111:DJ533 RS15170
gene id: 1871111:DJ533_RS15170
uniprot id: A0A2S2FG98
names: Similarity
messages: Belongs to the hemerythrin family.

1871111:DJ533 RS11850
gene id: 1871111:DJ533_RS11850
uniprot id: A0A2S2FFW1
names: Similarity
messages: Belongs to the transposase 8 family.

1871111:DJ533 RS16695
gene id: 1871111:DJ533_RS16695
uniprot id: A0A2S2FGJ2
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1871111:DJ533 RS14875
gene id: 1871111:DJ533_RS14875
uniprot id: A0A2S2FHC8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.

1871111:DJ533 RS06790
gene id: 1871111:DJ533_RS06790
uniprot id: A0A2S2FBW9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1871111:DJ533 RS14975
gene id: 1871111:DJ533_RS14975
uniprot id: A0A2S2FFS9
names: Subcellular Location Annotation
messages: Membrane

1871111:DJ533 RS04195
gene id: 1871111:DJ533_RS04195
uniprot id: A0A2S2FAD6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerD subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

1871111:DJ533 RS04585
gene id: 1871111:DJ533_RS04585
uniprot id: A0A2S2FAU2
names: Similarity
messages: Belongs to the Gfa family.

1871111:DJ533 RS11110
gene id: 1871111:DJ533_RS11110
uniprot id: A0A2S2FDV9
names: Subcellular Location Annotation
messages: Membrane

1871111:DJ533 RS09250
gene id: 1871111:DJ533_RS09250
uniprot id: A0A2S2FEI7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1871111:DJ533 RS05430
gene id: 1871111:DJ533_RS05430
uniprot id: A0A2S2FAS0
names: Function
names: Similarity
messages: Belongs to the Ap4A hydrolase family.
messages: Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP.

1871111:DJ533 RS15760
gene id: 1871111:DJ533_RS15760
uniprot id: A0A2S2FG17
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. RlmD subfamily.
messages: Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA.

1871111:DJ533 RS11455
gene id: 1871111:DJ533_RS11455
uniprot id: A0A2S2FDX5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2).
messages: Homodimer.

1871111:DJ533 RS14820
gene id: 1871111:DJ533_RS14820
uniprot id: A0A2S2FFK1
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily.
messages: Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl-L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway.

1871111:DJ533 RS17205
gene id: 1871111:DJ533_RS17205
uniprot id: A0A2S2FIJ6
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

1871111:DJ533 RS14065
gene id: 1871111:DJ533_RS14065
uniprot id: A0A2S2FFA4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

1871111:DJ533 RS03925
gene id: 1871111:DJ533_RS03925
uniprot id: A0A2S2FA21
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. Thiolase family.
messages: Catalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed.
messages: Cytoplasm
messages: Heterotetramer of two alpha chains (FadB) and two beta chains (FadA).

1871111:DJ533 RS02080
gene id: 1871111:DJ533_RS02080
uniprot id: A0A2S2F911
names: Similarity
messages: Belongs to the intradiol ring-cleavage dioxygenase family.

1871111:DJ533 RS13855
gene id: 1871111:DJ533_RS13855
uniprot id: A0A2S2FF37
names: Caution
names: Function
names: Similarity
messages: Belongs to the precorrin methyltransferase family.
messages: In the C-terminal section; belongs to the precorrin methyltransferase family.
messages: In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme.

1871111:DJ533 RS03845
gene id: 1871111:DJ533_RS03845
uniprot id: A0A2S2F9Y6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1871111:DJ533 RS02730
gene id: 1871111:DJ533_RS02730
uniprot id: A0A2S2FBC6
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1871111:DJ533 RS07335
gene id: 1871111:DJ533_RS07335
uniprot id: A0A2S2FBX7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. PrmA family.
messages: Cytoplasm
messages: Methylates ribosomal protein L11.

1871111:DJ533 RS13985
gene id: 1871111:DJ533_RS13985
uniprot id: A0A2S2FF65
names: Subcellular Location Annotation
messages: Membrane

1871111:DJ533 RS03660
gene id: 1871111:DJ533_RS03660
uniprot id: A0A2S2F9V8
names: Similarity
messages: Belongs to the pirin family.

1871111:DJ533 RS18510
gene id: 1871111:DJ533_RS18510
uniprot id: A0A2S2FHM5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbC subfamily.
messages: Periplasm
messages: Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process.

1871111:DJ533 RS01315
gene id: 1871111:DJ533_RS01315
uniprot id: A0A2S2F8H1
names: Function
names: Similarity
messages: Belongs to the DHPS family.
messages: Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives.

1871111:DJ533 RS15285
gene id: 1871111:DJ533_RS15285
uniprot id: A0A2S2FFS4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

1871111:DJ533 RS04110
gene id: 1871111:DJ533_RS04110
uniprot id: A0A2S2FBZ3
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1871111:DJ533 RS09295
gene id: 1871111:DJ533_RS09295
uniprot id: A0A2S2FCP9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1871111:DJ533 RS04410
gene id: 1871111:DJ533_RS04410
uniprot id: A0A2S2FC41
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

1871111:DJ533 RS06195
gene id: 1871111:DJ533_RS06195
uniprot id: A0A2S2FB44
names: Subcellular Location Annotation
messages: Membrane

1871111:DJ533 RS17350
gene id: 1871111:DJ533_RS17350
uniprot id: A0A2S2FH11
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

1871111:DJ533 RS14260
gene id: 1871111:DJ533_RS14260
uniprot id: A0A2S2FFC5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Cell inner membrane
messages: Membrane

1871111:DJ533 RS01190
gene id: 1871111:DJ533_RS01190
uniprot id: A0A2S2F8S0
names: Similarity
messages: Belongs to the IS21/IS1162 putative ATP-binding protein family.

1871111:DJ533 RS16020
gene id: 1871111:DJ533_RS16020
uniprot id: A0A2S2FG57
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1871111:DJ533 RS18400
gene id: 1871111:DJ533_RS18400
uniprot id: A0A2S2FHK5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

1871111:DJ533 RS07025
gene id: 1871111:DJ533_RS07025
uniprot id: A0A2S2FBR8
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvA family.
messages: Cytoplasm
messages: Has three domains with a flexible linker between the domains II and III and assumes an 'L' shape. Domain III is highly mobile and contacts RuvB.
messages: Homotetramer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

1871111:DJ533 RS11200
gene id: 1871111:DJ533_RS11200
uniprot id: A0A2S2FDP6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class II fructose-bisphosphate aldolase family.
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.
messages: Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.
messages: One is catalytic and the other provides a structural contribution.

1871111:DJ533 RS10360
gene id: 1871111:DJ533_RS10360
uniprot id: A0A2S2FD88
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

1871111:DJ533 RS14225
gene id: 1871111:DJ533_RS14225
uniprot id: A0A2S2FFG3
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.

1871111:DJ533 RS04140
gene id: 1871111:DJ533_RS04140
uniprot id: A0A2S2FAC6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptF/LptG family.
messages: Component of the lipopolysaccharide transport and assembly complex. The LptBFG transporter is composed of two ATP-binding proteins (LptB) and two transmembrane proteins (LptF and LptG).
messages: Membrane
messages: Part of the ABC transporter complex LptBFG involved in the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane.

1871111:DJ533 RS08820
gene id: 1871111:DJ533_RS08820
uniprot id: A0A2S2FCP3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the KdsC family.
messages: Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate.
messages: Homotetramer.

1871111:DJ533 RS13660
gene id: 1871111:DJ533_RS13660
uniprot id: A0A2S2FGU5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transglycosylase MltG family.
messages: Cell inner membrane
messages: Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.

1871111:DJ533 RS01200
gene id: 1871111:DJ533_RS01200
uniprot id: A0A2S2F8J4
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

1871111:DJ533 RS16430
gene id: 1871111:DJ533_RS16430
uniprot id: A0A2S2FGE1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

1871111:DJ533 RS16395
gene id: 1871111:DJ533_RS16395
uniprot id: A0A2S2FGK6
names: Cofactor
messages: Binds 1 Fe(2+) ion per subunit.

1871111:DJ533 RS07560
gene id: 1871111:DJ533_RS07560
uniprot id: A0A2S2FBV8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

1871111:DJ533 RS03625
gene id: 1871111:DJ533_RS03625
uniprot id: A0A2S2F9X0
names: Subcellular Location Annotation
messages: Membrane

1871111:DJ533 RS13635
gene id: 1871111:DJ533_RS13635
uniprot id: A0A2S2FF08
names: Subcellular Location Annotation
messages: Membrane

1871111:DJ533 RS07765
gene id: 1871111:DJ533_RS07765
uniprot id: A0A2S2FBZ7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

1871111:DJ533 RS03135
gene id: 1871111:DJ533_RS03135
uniprot id: A0A2S2F9V1
names: Cofactor
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.
messages: Probably binds two magnesium or manganese ions per subunit.

1871111:DJ533 RS11405
gene id: 1871111:DJ533_RS11405
uniprot id: A0A2S2FDS8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AFG1 ATPase family. ZapE subfamily.
messages: Cytoplasm
messages: Interacts with FtsZ.
messages: Reduces the stability of FtsZ polymers in the presence of ATP.

1871111:DJ533 RS16295
gene id: 1871111:DJ533_RS16295
uniprot id: A0A2S2FGI7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 3 family. NagZ subfamily.
messages: Cytoplasm
messages: Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide-linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N-acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides.

1871111:DJ533 RS13385
gene id: 1871111:DJ533_RS13385
uniprot id: A0A2S2FGQ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell inner membrane
messages: Membrane

1871111:DJ533 RS12330
gene id: 1871111:DJ533_RS12330
uniprot id: A0A2S2FG49
names: Cofactor
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

1871111:DJ533 RS14175
gene id: 1871111:DJ533_RS14175
uniprot id: A0A2S2FFF2
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1871111:DJ533 RS09260
gene id: 1871111:DJ533_RS09260
uniprot id: A0A2S2FCR1
names: Similarity
messages: Belongs to the HIBADH-related family.

1871111:DJ533 RS08465
gene id: 1871111:DJ533_RS08465
uniprot id: A0A2S2FCC7
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Member of the two-component regulatory system NtrB/NtrC, which controls expression of the nitrogen-regulated (ntr) genes in response to nitrogen limitation. Phosphorylated NtrC binds directly to DNA and stimulates the formation of open promoter-sigma54-RNA polymerase complexes.

1871111:DJ533 RS13100
gene id: 1871111:DJ533_RS13100
uniprot id: A0A2S2FET5
names: Cofactor
names: Similarity
messages: Belongs to the DNA photolyase class-1 family.
messages: Belongs to the DNA photolyase family.
messages: Binds 1 FAD per subunit.

1871111:DJ533 RS01835
gene id: 1871111:DJ533_RS01835
uniprot id: A0A2S2F8Y4
names: Function
messages: Involved in the transposition of the insertion sequence.

1871111:DJ533 RS13170
gene id: 1871111:DJ533_RS13170
uniprot id: A0A2S2FGK9
names: Cofactor
messages: Binds 1 Mg(2+) ion per subunit.

1871111:DJ533 RS03130
gene id: 1871111:DJ533_RS03130
uniprot id: A0A2S2F9N3
names: Similarity
messages: Belongs to the ArsC family.

1871111:DJ533 RS12245
gene id: 1871111:DJ533_RS12245
uniprot id: A0A2S2FEQ7
names: Cofactor
names: Similarity
messages: Belongs to the MsrB Met sulfoxide reductase family.
messages: Binds 1 zinc ion per subunit. The zinc ion is important for the structural integrity of the protein.

1871111:DJ533 RS14150
gene id: 1871111:DJ533_RS14150
uniprot id: A0A2S2FF80
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

1871111:DJ533 RS05095
gene id: 1871111:DJ533_RS05095
uniprot id: A0A2S2FAJ7
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

1871111:DJ533 RS07835
gene id: 1871111:DJ533_RS07835
uniprot id: A0A2S2FBY1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
messages: Homodimer.

1871111:DJ533 RS02960
gene id: 1871111:DJ533_RS02960
uniprot id: A0A2S2F9I9
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1871111:DJ533 RS07500
gene id: 1871111:DJ533_RS07500
uniprot id: A0A2S2FBV1
names: Subcellular Location Annotation
messages: Membrane

1871111:DJ533 RS17970
gene id: 1871111:DJ533_RS17970
uniprot id: A0A2S2FH87
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

1871111:DJ533 RS12965
gene id: 1871111:DJ533_RS12965
uniprot id: A0A2S2FEQ4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase H family.
messages: Binds 1 Mg(2+) ion per subunit. May bind a second metal ion at a regulatory site, or after substrate binding.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Monomer.

1871111:DJ533 RS08835
gene id: 1871111:DJ533_RS08835
uniprot id: A0A2S2FCG9
names: Function
names: Similarity
messages: Belongs to the ABC transporter superfamily. Outer membrane lipopolysaccharide export (TC 1.B.42) family.
messages: Part of the ABC transporter complex LptBFG involved in the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane. Probably responsible for energy coupling to the transport system.

1871111:DJ533 RS12915
gene id: 1871111:DJ533_RS12915
uniprot id: A0A2S2FEP4
names: Cofactor
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: A single active site specifically recognizes both ATP and CTP and is responsible for their addition.
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. Bacterial CCA-adding enzyme type 1 subfamily.
messages: Catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. tRNA 3'-terminal CCA addition is required both for tRNA processing and repair. Also involved in tRNA surveillance by mediating tandem CCA addition to generate a CCACCA at the 3' terminus of unstable tRNAs. While stable tRNAs receive only 3'-terminal CCA, unstable tRNAs are marked with CCACCA and rapidly degraded.
messages: Comprises two domains: an N-terminal domain containing the nucleotidyltransferase activity and a C-terminal HD domain associated with both phosphodiesterase and phosphatase activities.
messages: Magnesium is required for nucleotidyltransferase activity.
messages: Monomer. Can also form homodimers and oligomers.
messages: Nickel for phosphatase activity.

1871111:DJ533 RS02230
gene id: 1871111:DJ533_RS02230
uniprot id: A0A2S2F8Y9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MerP family.
messages: Involved in mercury resistance. Acts as a mercury scavenger that specifically binds to a mercuric ion in the periplasm and probably passes it to the cytoplasmic mercuric reductase MerA via the mercuric transport protein MerT.
messages: Monomer.
messages: Periplasm

1871111:DJ533 RS17415
gene id: 1871111:DJ533_RS17415
uniprot id: A0A2S2FH36
names: Function
names: Similarity
messages: Belongs to the nucleoside phosphorylase PpnP family.
messages: Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions.

1871111:DJ533 RS04420
gene id: 1871111:DJ533_RS04420
uniprot id: A0A2S2FA95
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1871111:DJ533 RS11480
gene id: 1871111:DJ533_RS11480
uniprot id: A0A2S2FDW3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP J family.
messages: Cell inner membrane
messages: Membrane

1871111:DJ533 RS08130
gene id: 1871111:DJ533_RS08130
uniprot id: A0A2S2FC45
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptide transporter carbon starvation (CstA) (TC 2.A.114) family.
messages: Membrane

1871111:DJ533 RS15440
gene id: 1871111:DJ533_RS15440
uniprot id: A0A2S2FGF0
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

1871111:DJ533 RS05075
gene id: 1871111:DJ533_RS05075
uniprot id: A0A2S2FAK8
names: Subcellular Location Annotation
messages: Membrane

1871111:DJ533 RS07305
gene id: 1871111:DJ533_RS07305
uniprot id: A0A2S2FBQ0
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with bS18 to 16S ribosomal RNA.

1871111:DJ533 RS05190
gene id: 1871111:DJ533_RS05190
uniprot id: A0A2S2FAM7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. Xpt subfamily.
messages: Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis.
messages: Cytoplasm
messages: Homodimer.

1871111:DJ533 RS03350
gene id: 1871111:DJ533_RS03350
uniprot id: A0A2S2FA74
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HAK/KUP transporter (TC 2.A.72) family.
messages: Cell membrane
messages: Membrane
messages: Transport of potassium into the cell. Likely operates as a K(+):H(+) symporter.

1871111:DJ533 RS14830
gene id: 1871111:DJ533_RS14830
uniprot id: A0A2S2FFK5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily.
messages: Catalyzes the transfer of the alpha-amino group from S-adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only aminotransferase known to utilize SAM as an amino donor.
messages: Cytoplasm
messages: Homodimer.

1871111:DJ533 RS04860
gene id: 1871111:DJ533_RS04860
uniprot id: A0A2S2FAY9
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

1871111:DJ533 RS16515
gene id: 1871111:DJ533_RS16515
uniprot id: A0A2S2FGI9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

1871111:DJ533 RS05425
gene id: 1871111:DJ533_RS05425
uniprot id: A0A2S2FB83
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

1871111:DJ533 RS07320
gene id: 1871111:DJ533_RS07320
uniprot id: A0A2S2FBN8
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

1871111:DJ533 RS18450
gene id: 1871111:DJ533_RS18450
uniprot id: A0A2S2FHL4
names: Function
names: Similarity
messages: Belongs to the MurCDEF family. Mpl subfamily.
messages: Reutilizes the intact tripeptide L-alanyl-gamma-D-glutamyl-meso-diaminopimelate by linking it to UDP-N-acetylmuramate.

1871111:DJ533 RS03140
gene id: 1871111:DJ533_RS03140
uniprot id: A0A2S2F9N2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.

1871111:DJ533 RS16915
gene id: 1871111:DJ533_RS16915
uniprot id: A0A2S2FH65
names: Similarity
messages: Belongs to the outer membrane porin (Opr) (TC 1.B.25) family.

1871111:DJ533 RS17595
gene id: 1871111:DJ533_RS17595
uniprot id: A0A2S2FGZ7
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1871111:DJ533 RS06940
gene id: 1871111:DJ533_RS06940
uniprot id: A0A2S2FBG6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1871111:DJ533 RS09650
gene id: 1871111:DJ533_RS09650
uniprot id: A0A2S2FCV9
names: Function
names: Similarity
messages: Belongs to the heat shock protein 70 family.
messages: Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB.

1871111:DJ533 RS06110
gene id: 1871111:DJ533_RS06110
uniprot id: A0A2S2FBK3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

1871111:DJ533 RS05465
gene id: 1871111:DJ533_RS05465
uniprot id: A0A2S2FAT9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1871111:DJ533 RS15050
gene id: 1871111:DJ533_RS15050
uniprot id: A0A2S2FFN0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

1871111:DJ533 RS03010
gene id: 1871111:DJ533_RS03010
uniprot id: A0A2S2F9J9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsQ/DivIB family. FtsQ subfamily.
messages: Cell inner membrane
messages: Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly.
messages: Part of a complex composed of FtsB, FtsL and FtsQ.

1871111:DJ533 RS01115
gene id: 1871111:DJ533_RS01115
uniprot id: A0A2S2F8S7
names: Similarity
messages: Belongs to the DNA polymerase type-Y family.

1871111:DJ533 RS14545
gene id: 1871111:DJ533_RS14545
uniprot id: A0A2S2FFM6
names: Function
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
messages: Catalyzes the reversible oxidative deamination of glutamate to alpha-ketoglutarate and ammonia.

1871111:DJ533 RS15830
gene id: 1871111:DJ533_RS15830
uniprot id: A0A2S2FGB1
names: Similarity
messages: Belongs to the peptidase S66 family.

1871111:DJ533 RS08905
gene id: 1871111:DJ533_RS08905
uniprot id: A0A2S2FCH2
names: Similarity
messages: Belongs to the peptidase C56 family.

1871111:DJ533 RS02700
gene id: 1871111:DJ533_RS02700
uniprot id: A0A2S2F9E1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

1871111:DJ533 RS16440
gene id: 1871111:DJ533_RS16440
uniprot id: A0A2S2FGJ7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

1871111:DJ533 RS13865
gene id: 1871111:DJ533_RS13865
uniprot id: A0A2S2FF99
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1871111:DJ533 RS09875
gene id: 1871111:DJ533_RS09875
uniprot id: A0A2S2FD01
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IA subfamily.
messages: Cell membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system and for the release of the potassium ions to the cytoplasm.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

1871111:DJ533 RS05035
gene id: 1871111:DJ533_RS05035
uniprot id: A0A2S2FAL3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

1871111:DJ533 RS02330
gene id: 1871111:DJ533_RS02330
uniprot id: A0A2S2F904
names: Similarity
messages: Belongs to the acetaldehyde dehydrogenase family.

1871111:DJ533 RS14865
gene id: 1871111:DJ533_RS14865
uniprot id: A0A2S2FFS6
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1871111:DJ533 RS16220
gene id: 1871111:DJ533_RS16220
uniprot id: A0A2S2FGA1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine-cytosine permease (2.A.39) family.
messages: Membrane

1871111:DJ533 RS06805
gene id: 1871111:DJ533_RS06805
uniprot id: A0A2S2FBM7
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.

1871111:DJ533 RS04190
gene id: 1871111:DJ533_RS04190
uniprot id: A0A2S2FA76
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbC subfamily.
messages: Periplasm
messages: Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process.

1871111:DJ533 RS09755
gene id: 1871111:DJ533_RS09755
uniprot id: A0A2S2FCX9
names: Similarity
messages: Belongs to the AB hydrolase superfamily. AB hydrolase 4 family.

1871111:DJ533 RS11580
gene id: 1871111:DJ533_RS11580
uniprot id: A0A2S2FFR5
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1871111:DJ533 RS02750
gene id: 1871111:DJ533_RS02750
uniprot id: A0A2S2F9F0
names: Cofactor
names: Function
names: Similarity
messages: Adenine glycosylase active on G-A mispairs. MutY also corrects error-prone DNA synthesis past GO lesions which are due to the oxidatively damaged form of guanine: 7,8-dihydro-8-oxoguanine (8-oxo-dGTP).
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.

1871111:DJ533 RS17400
gene id: 1871111:DJ533_RS17400
uniprot id: A0A2S2FHE7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

1871111:DJ533 RS12910
gene id: 1871111:DJ533_RS12910
uniprot id: A0A2S2FEL8
names: Similarity
messages: In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.
messages: In the N-terminal section; belongs to the malic enzymes family.

1871111:DJ533 RS03585
gene id: 1871111:DJ533_RS03585
uniprot id: A0A2S2F9T5
names: Similarity
messages: Belongs to the glutathione peroxidase family.

1871111:DJ533 RS16015
gene id: 1871111:DJ533_RS16015
uniprot id: A0A2S2FGE0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial histone-like protein family.
messages: Heterodimer of an alpha and a beta chain.
messages: This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.

1871111:DJ533 RS05685
gene id: 1871111:DJ533_RS05685
uniprot id: A0A2S2FAW7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SbcD family.
messages: Heterodimer of SbcC and SbcD.
messages: SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity.

1871111:DJ533 RS08870
gene id: 1871111:DJ533_RS08870
uniprot id: A0A2S2FCQ4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the serine/threonine dehydratase family.
messages: Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.
messages: Homotetramer.

1871111:DJ533 RS16800
gene id: 1871111:DJ533_RS16800
uniprot id: A0A2S2FGK1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm

1871111:DJ533 RS16840
gene id: 1871111:DJ533_RS16840
uniprot id: A0A2S2FGR5
names: Similarity
messages: Belongs to the catalase family.

1871111:DJ533 RS08525
gene id: 1871111:DJ533_RS08525
uniprot id: A0A2S2FCA8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioester dehydratase family. FabZ subfamily.
messages: Cytoplasm
messages: Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.

1871111:DJ533 RS04300
gene id: 1871111:DJ533_RS04300
uniprot id: A0A2S2FAQ1
names: Function
names: Similarity
messages: Belongs to the uroporphyrinogen-III synthase family.
messages: Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.

1871111:DJ533 RS08445
gene id: 1871111:DJ533_RS08445
uniprot id: A0A2S2FCR6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1871111:DJ533 RS06385
gene id: 1871111:DJ533_RS06385
uniprot id: A0A2S2FBF3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Cell inner membrane
messages: Homoheptamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mechanosensitive channel that participates in the regulation of osmotic pressure changes within the cell, opening in response to stretch forces in the membrane lipid bilayer, without the need for other proteins. Contributes to normal resistance to hypoosmotic shock. Forms an ion channel of 1.0 nanosiemens conductance with a slight preference for anions.

1871111:DJ533 RS09070
gene id: 1871111:DJ533_RS09070
uniprot id: A0A2S2FCN7
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1871111:DJ533 RS09110
gene id: 1871111:DJ533_RS09110
uniprot id: A0A2S2FCK7
names: Function
names: Similarity
messages: Belongs to the class-I DAHP synthase family.
messages: Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP).

1871111:DJ533 RS08580
gene id: 1871111:DJ533_RS08580
uniprot id: A0A2S2FCE7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

1871111:DJ533 RS04335
gene id: 1871111:DJ533_RS04335
uniprot id: A0A2S2FC31
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial secretin family. GSP D subfamily.
messages: Cell outer membrane
messages: Membrane

1871111:DJ533 RS10365
gene id: 1871111:DJ533_RS10365
uniprot id: A0A2S2FDA7
names: Subcellular Location Annotation
messages: Membrane

1871111:DJ533 RS04750
gene id: 1871111:DJ533_RS04750
uniprot id: A0A2S2FAX0
names: Subunit
messages: Homodimer.

1871111:DJ533 RS15335
gene id: 1871111:DJ533_RS15335
uniprot id: A0A2S2FFT5
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

1871111:DJ533 RS08815
gene id: 1871111:DJ533_RS08815
uniprot id: A0A2S2FHM9
names: Similarity
messages: Belongs to the SIS family. GutQ/KpsF subfamily.

1871111:DJ533 RS13640
gene id: 1871111:DJ533_RS13640
uniprot id: A0A2S2FF60
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily.
messages: Catalyzes the oxidation of L-aspartate to iminoaspartate.
messages: Cytoplasm

1871111:DJ533 RS07295
gene id: 1871111:DJ533_RS07295
uniprot id: A0A2S2FDK8
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

1871111:DJ533 RS04415
gene id: 1871111:DJ533_RS04415
uniprot id: A0A1P8L0A0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1871111:DJ533 RS13670
gene id: 1871111:DJ533_RS13670
uniprot id: A0A2S2FHS4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic sulfate-binding protein family.
messages: Periplasm

1871111:DJ533 RS13920
gene id: 1871111:DJ533_RS13920
uniprot id: A0A2S2FFB0
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1871111:DJ533 RS07490
gene id: 1871111:DJ533_RS07490
uniprot id: A0A2S2FBZ9
names: Subcellular Location Annotation
messages: Membrane

1871111:DJ533 RS05760
gene id: 1871111:DJ533_RS05760
uniprot id: A0A2S2FBE3
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.
messages: In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family.

1871111:DJ533 RS17105
gene id: 1871111:DJ533_RS17105
uniprot id: A0A2S2FGT6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

1871111:DJ533 RS05040
gene id: 1871111:DJ533_RS05040
uniprot id: A0A2S2FAQ9
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

1871111:DJ533 RS17270
gene id: 1871111:DJ533_RS17270
uniprot id: A0A2S2FHC6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

1871111:DJ533 RS17285
gene id: 1871111:DJ533_RS17285
uniprot id: A0A2S2FH16
names: Similarity
messages: Belongs to the RutC family.

1871111:DJ533 RS17480
gene id: 1871111:DJ533_RS17480
uniprot id: A0A2S2FH43
names: Subcellular Location Annotation
messages: Membrane

1871111:DJ533 RS08200
gene id: 1871111:DJ533_RS08200
uniprot id: A0A2S2FCB9
names: Similarity
messages: Belongs to the TrpC family.

1871111:DJ533 RS05945
gene id: 1871111:DJ533_RS05945
uniprot id: A0A2S2FCX2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

1871111:DJ533 RS03970
gene id: 1871111:DJ533_RS03970
uniprot id: A0A2S2FA98
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

1871111:DJ533 RS10265
gene id: 1871111:DJ533_RS10265
uniprot id: A0A2S2FD72
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEDS family. MrdB/RodA subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Peptidoglycan polymerase that is essential for cell wall elongation.

1871111:DJ533 RS16070
gene id: 1871111:DJ533_RS16070
uniprot id: A0A2S2FGC8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

1871111:DJ533 RS06435
gene id: 1871111:DJ533_RS06435
uniprot id: A0A2S2FBA3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1871111:DJ533 RS14885
gene id: 1871111:DJ533_RS14885
uniprot id: A0A2S2FFN1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1871111:DJ533 RS14490
gene id: 1871111:DJ533_RS14490
uniprot id: A0A2S2FFF6
names: Similarity
messages: Belongs to the CutA family.

1871111:DJ533 RS01195
gene id: 1871111:DJ533_RS01195
uniprot id: A0A2S2F8M8
names: Caution
names: Similarity
messages: Belongs to the MsrB Met sulfoxide reductase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1871111:DJ533 RS17555
gene id: 1871111:DJ533_RS17555
uniprot id: A0A2S2FHH7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1871111:DJ533 RS01865
gene id: 1871111:DJ533_RS01865
uniprot id: A0A2S2F9D1
names: Similarity
messages: Belongs to the class-D beta-lactamase family.

1871111:DJ533 RS09085
gene id: 1871111:DJ533_RS09085
uniprot id: A0A2S2FEG5
names: Similarity
messages: Belongs to the Lgt family.

1871111:DJ533 RS16110
gene id: 1871111:DJ533_RS16110
uniprot id: A0A2S2FGS0
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1871111:DJ533 RS06785
gene id: 1871111:DJ533_RS06785
uniprot id: A0A2S2FBF5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NfuA family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is presumably bound at the interface of two monomers.
messages: Homodimer.
messages: Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins.

1871111:DJ533 RS14145
gene id: 1871111:DJ533_RS14145
uniprot id: A0A2S2FH14
names: Function
names: Similarity
messages: Belongs to the DHPS family.
messages: Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives.

1871111:DJ533 RS02660
gene id: 1871111:DJ533_RS02660
uniprot id: A0A2S2F9M0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1871111:DJ533 RS17530
gene id: 1871111:DJ533_RS17530
uniprot id: A0A2S2FH53
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

1871111:DJ533 RS12170
gene id: 1871111:DJ533_RS12170
uniprot id: A0A2S2FE72
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LemA family.
messages: Membrane

1871111:DJ533 RS07875
gene id: 1871111:DJ533_RS07875
uniprot id: A0A2S2FBX5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EamA transporter family.
messages: Membrane

1871111:DJ533 RS16520
gene id: 1871111:DJ533_RS16520
uniprot id: A0A2S2FGZ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

1871111:DJ533 RS12160
gene id: 1871111:DJ533_RS12160
uniprot id: A0A2S2FE99
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1871111:DJ533 RS08350
gene id: 1871111:DJ533_RS08350
uniprot id: A0A2S2FC71
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. TrmA subfamily.
messages: Dual-specificity methyltransferase that catalyzes the formation of 5-methyluridine at position 54 (m5U54) in all tRNAs, and that of position 341 (m5U341) in tmRNA (transfer-mRNA).

1871111:DJ533 RS17870
gene id: 1871111:DJ533_RS17870
uniprot id: A0A2S2FH57
names: Similarity
messages: Belongs to the DprA/Smf family.

1871111:DJ533 RS13875
gene id: 1871111:DJ533_RS13875
uniprot id: A0A2S2FHT1
names: Cofactor
names: Similarity
messages: Belongs to the carotenoid oxygenase family.
messages: Binds 1 Fe(2+) ion per subunit.

1871111:DJ533 RS14675
gene id: 1871111:DJ533_RS14675
uniprot id: A0A2S2FFJ4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M20A family. DapE subfamily.
messages: Binds 2 Zn(2+) or Co(2+) ions per subunit.
messages: Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls.
messages: Homodimer.

1871111:DJ533 RS10390
gene id: 1871111:DJ533_RS10390
uniprot id: A0A2S2FI89
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0060 family.
messages: Cell membrane

1871111:DJ533 RS12860
gene id: 1871111:DJ533_RS12860
uniprot id: A0A2S2FEK9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family.
messages: Cell membrane
messages: Membrane

1871111:DJ533 RS15950
gene id: 1871111:DJ533_RS15950
uniprot id: A0A2S2FG50
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: ATPase component of the type II secretion system required for the energy-dependent secretion of extracellular factors such as proteases and toxins from the periplasm. Acts as a molecular motor to provide the energy that is required for assembly of the pseudopilus and the extrusion of substrates generated in the cytoplasm.
messages: Belongs to the GSP E family.
messages: Cell inner membrane

1871111:DJ533 RS10325
gene id: 1871111:DJ533_RS10325
uniprot id: A0A2S2FHN9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dsrC/tusE family.
messages: Cytoplasm
messages: Part of a sulfur-relay system.

1871111:DJ533 RS06620
gene id: 1871111:DJ533_RS06620
uniprot id: A0A2S2FBB0
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

1871111:DJ533 RS04235
gene id: 1871111:DJ533_RS04235
uniprot id: A0A2S2FAP0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DksA family.
messages: Cytoplasm
messages: Interacts directly with the RNA polymerase.
messages: Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters. Also required for regulation of fis expression.

1871111:DJ533 RS04950
gene id: 1871111:DJ533_RS04950
uniprot id: A0A2S2FCE6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

1871111:DJ533 RS02235
gene id: 1871111:DJ533_RS02235
uniprot id: A0A2S2F9F6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.
messages: Resistance to Hg(2+) in bacteria appears to be governed by a specialized system which includes mercuric reductase. MerA protein is responsible for volatilizing mercury as Hg(0).

1871111:DJ533 RS14080
gene id: 1871111:DJ533_RS14080
uniprot id: A0A2S2FH04
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoenolpyruvate carboxykinase [GTP] family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle.
messages: Cytoplasm
messages: Monomer.

1871111:DJ533 RS18095
gene id: 1871111:DJ533_RS18095
uniprot id: A0A2S2FHG2
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

1871111:DJ533 RS02825
gene id: 1871111:DJ533_RS02825
uniprot id: A0A2S2F9I6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
messages: Cell inner membrane

1871111:DJ533 RS04230
gene id: 1871111:DJ533_RS04230
uniprot id: A0A2S2FHI9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. GluQ subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5-dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon.

1871111:DJ533 RS07635
gene id: 1871111:DJ533_RS07635
uniprot id: A0A2S2FBV5
names: Function
names: Similarity
messages: Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PSRP subfamily.
messages: Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation/dephosphorylation.

1871111:DJ533 RS09385
gene id: 1871111:DJ533_RS09385
uniprot id: A0A2S2FCY7
names: Function
names: Similarity
messages: Belongs to the Thz kinase family.
messages: Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ).

1871111:DJ533 RS04375
gene id: 1871111:DJ533_RS04375
uniprot id: A0A2S2FFS4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

1871111:DJ533 RS13410
gene id: 1871111:DJ533_RS13410
uniprot id: A0A2S2FEW8
names: Function
names: Similarity
messages: Belongs to the RlpA family.
messages: Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides.

1871111:DJ533 RS13685
gene id: 1871111:DJ533_RS13685
uniprot id: A0A2S2FF04
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Membrane
messages: Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (CysA), two transmembrane proteins (CysT and CysW) and a solute-binding protein (CysP).

1871111:DJ533 RS05310
gene id: 1871111:DJ533_RS05310
uniprot id: A0A2S2FAP6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

1871111:DJ533 RS11745
gene id: 1871111:DJ533_RS11745
uniprot id: A0A2S2FDY1
names: Subcellular Location Annotation
messages: Membrane

1871111:DJ533 RS18100
gene id: 1871111:DJ533_RS18100
uniprot id: A0A2S2FHE5
names: Similarity
messages: Belongs to the polysaccharide synthase family.

1871111:DJ533 RS08700
gene id: 1871111:DJ533_RS08700
uniprot id: A0A2S2FCM3
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0756 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1871111:DJ533 RS16280
gene id: 1871111:DJ533_RS16280
uniprot id: A0A2S2FGA9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
messages: Cytoplasm
messages: Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.

1871111:DJ533 RS17280
gene id: 1871111:DJ533_RS17280
uniprot id: A0A2S2FGU6
names: Similarity
messages: Belongs to the RelA/SpoT family.

1871111:DJ533 RS04680
gene id: 1871111:DJ533_RS04680
uniprot id: A0A2S2FAD1
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fluoride channel Fluc/FEX (TC 1.A.43) family.
messages: Cell membrane
messages: Fluoride-specific ion channel. Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane
messages: Na(+) is not transported, but it plays an essential structural role and its presence is essential for fluoride channel function.

1871111:DJ533 RS14990
gene id: 1871111:DJ533_RS14990
uniprot id: A0A2S2FHE2
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Homooctamer.

1871111:DJ533 RS12295
gene id: 1871111:DJ533_RS12295
uniprot id: A0A2S2FER8
names: Similarity
messages: Belongs to the YkuD family.

1871111:DJ533 RS11435
gene id: 1871111:DJ533_RS11435
uniprot id: A0A2S2FEA4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial histone-like protein family.
messages: Heterodimer of an alpha and a beta chain.
messages: This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.

1871111:DJ533 RS03400
gene id: 1871111:DJ533_RS03400
uniprot id: A0A2S2FA83
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Cell inner membrane
messages: Homoheptamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mechanosensitive channel that participates in the regulation of osmotic pressure changes within the cell, opening in response to stretch forces in the membrane lipid bilayer, without the need for other proteins. Contributes to normal resistance to hypoosmotic shock. Forms an ion channel of 1.0 nanosiemens conductance with a slight preference for anions.
messages: Membrane

1871111:DJ533 RS02790
gene id: 1871111:DJ533_RS02790
uniprot id: A0A2S2FBD5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

1871111:DJ533 RS06555
gene id: 1871111:DJ533_RS06555
uniprot id: A0A2S2FBB1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

1871111:DJ533 RS02990
gene id: 1871111:DJ533_RS02990
uniprot id: A0A2S2F9P4
names: Similarity
messages: Belongs to the prokaryotic GSH synthase family.

1871111:DJ533 RS17020
gene id: 1871111:DJ533_RS17020
uniprot id: A0A2S2FGW5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1871111:DJ533 RS17215
gene id: 1871111:DJ533_RS17215
uniprot id: A0A2S2FGV2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein uS19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein uS19.

1871111:DJ533 RS10230
gene id: 1871111:DJ533_RS10230
uniprot id: A0A2S2FDA2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fatty acid desaturase type 1 family. AlkB subfamily.
messages: Cell inner membrane
messages: Membrane

1871111:DJ533 RS11325
gene id: 1871111:DJ533_RS11325
uniprot id: A0A2S2FDS0
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1871111:DJ533 RS05170
gene id: 1871111:DJ533_RS05170
uniprot id: A0A2S2FCI7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0761 family.
messages: Cell membrane
messages: Membrane

1871111:DJ533 RS03545
gene id: 1871111:DJ533_RS03545
uniprot id: A0A2S2F9T3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0). The b'-subunit is a diverged and duplicated form of b found in plants and photosynthetic bacteria.
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

1871111:DJ533 RS04780
gene id: 1871111:DJ533_RS04780
uniprot id: A0A2S2FAK9
names: Similarity
messages: Belongs to the DEAD box helicase family.

1871111:DJ533 RS11690
gene id: 1871111:DJ533_RS11690
uniprot id: A0A2S2FE07
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

1871111:DJ533 RS02255
gene id: 1871111:DJ533_RS02255
uniprot id: A0A2S2F8Y4
names: Function
messages: Involved in the transposition of the insertion sequence.

1871111:DJ533 RS05715
gene id: 1871111:DJ533_RS05715
uniprot id: A0A2S2FAW5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

1871111:DJ533 RS17340
gene id: 1871111:DJ533_RS17340
uniprot id: A0A2S2FGV6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

1871111:DJ533 RS09610
gene id: 1871111:DJ533_RS09610
uniprot id: A0A2S2FD48
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. PhnW subfamily.
messages: Homodimer.
messages: Involved in phosphonate degradation.

1871111:DJ533 RS06665
gene id: 1871111:DJ533_RS06665
uniprot id: A0A2S2FBD6
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1871111:DJ533 RS02710
gene id: 1871111:DJ533_RS02710
uniprot id: A0A2S2F9M9
names: Subcellular Location Annotation
messages: Membrane

1871111:DJ533 RS13140
gene id: 1871111:DJ533_RS13140
uniprot id: A0A2S2FER2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

1871111:DJ533 RS08495
gene id: 1871111:DJ533_RS08495
uniprot id: A0A2S2FCS5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

1871111:DJ533 RS15080
gene id: 1871111:DJ533_RS15080
uniprot id: A0A2S2FFU9
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

1871111:DJ533 RS02495
gene id: 1871111:DJ533_RS02495
uniprot id: A0A2S2F9A9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

1871111:DJ533 RS08170
gene id: 1871111:DJ533_RS08170
uniprot id: A0A2S2FE01
names: Subcellular Location Annotation
messages: Cytoplasm

1871111:DJ533 RS08715
gene id: 1871111:DJ533_RS08715
uniprot id: A0A2S2FCE9
names: Similarity
messages: Belongs to the RelB/DinJ antitoxin family.

1871111:DJ533 RS12945
gene id: 1871111:DJ533_RS12945
uniprot id: A0A2S2FET8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1871111:DJ533 RS05765
gene id: 1871111:DJ533_RS05765
uniprot id: A0A2S2FAX6
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1871111:DJ533 RS13330
gene id: 1871111:DJ533_RS13330
uniprot id: A0A2S2FGP0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.

1871111:DJ533 RS03760
gene id: 1871111:DJ533_RS03760
uniprot id: A0A2S2F9W5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits).
messages: In the C-terminal section; belongs to the transpeptidase family.
messages: In the N-terminal section; belongs to the glycosyltransferase 51 family.
messages: Membrane

1871111:DJ533 RS15140
gene id: 1871111:DJ533_RS15140
uniprot id: A0A2S2FFX5
names: Similarity
messages: Belongs to the GSP E family.

1871111:DJ533 RS08850
gene id: 1871111:DJ533_RS08850
uniprot id: A0A2S2FCG2
names: Similarity
messages: Belongs to the universal stress protein A family.

1871111:DJ533 RS03790
gene id: 1871111:DJ533_RS03790
uniprot id: A0A2S2F9X9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1871111:DJ533 RS17190
gene id: 1871111:DJ533_RS17190
uniprot id: A0A2S2FGY0
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

1871111:DJ533 RS16760
gene id: 1871111:DJ533_RS16760
uniprot id: A0A2S2FGK4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

1871111:DJ533 RS06730
gene id: 1871111:DJ533_RS06730
uniprot id: A0A2S2FBD0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

1871111:DJ533 RS10910
gene id: 1871111:DJ533_RS10910
uniprot id: A0A2S2FDK9
names: Similarity
messages: Belongs to the peptidase M16 family.

1871111:DJ533 RS08340
gene id: 1871111:DJ533_RS08340
uniprot id: A0A2S2FCP8
names: Similarity
messages: Belongs to the citrate synthase family.

1871111:DJ533 RS06695
gene id: 1871111:DJ533_RS06695
uniprot id: A0A2S2FBE7
names: Cofactor
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cell inner membrane
messages: Membrane
messages: Membrane-anchoring subunit of succinate dehydrogenase (SDH).
messages: Part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur protein, plus two membrane-anchoring proteins, SdhC and SdhD.
messages: The heme is bound between the two transmembrane subunits.

1871111:DJ533 RS07615
gene id: 1871111:DJ533_RS07615
uniprot id: A0A2S2FC29
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Membrane
messages: The cytochrome bo(3) ubiquinol oxidase complex is a heterooctamer of two A chains, two B chains, two C chains and two D chains.

1871111:DJ533 RS07830
gene id: 1871111:DJ533_RS07830
uniprot id: A0A2S2FC66
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase T family.
messages: Binds two Mg(2+) per subunit. The active form of the enzyme binds two Mg(2+) ions in its active site. The first Mg(2+) forms only one salt bridge with the protein.
messages: Homodimer.
messages: Trims short 3' overhangs of a variety of RNA species, leaving a one or two nucleotide 3' overhang. Responsible for the end-turnover of tRNA: specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis.

1871111:DJ533 RS15375
gene id: 1871111:DJ533_RS15375
uniprot id: A0A2S2FFX9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

1871111:DJ533 RS01255
gene id: 1871111:DJ533_RS01255
uniprot id: A0A2S2F8Y5
names: Function
names: Similarity
messages: Belongs to the glutaredoxin family.
messages: Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins.

1871111:DJ533 RS14745
gene id: 1871111:DJ533_RS14745
uniprot id: A0A2S2FFI7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

1871111:DJ533 RS04015
gene id: 1871111:DJ533_RS04015
uniprot id: A0A2S2FAK7
names: Similarity
messages: Belongs to the outer membrane porin (Opr) (TC 1.B.25) family.

1871111:DJ533 RS06615
gene id: 1871111:DJ533_RS06615
uniprot id: A0A2S2FBT9
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

1871111:DJ533 RS02040
gene id: 1871111:DJ533_RS02040
uniprot id: A0A2S2F950
names: Function
messages: Involved in the transposition of the insertion sequence.

1871111:DJ533 RS13805
gene id: 1871111:DJ533_RS13805
uniprot id: A0A2S2FF27
names: Similarity
messages: Belongs to the UPF0250 family.

1871111:DJ533 RS13555
gene id: 1871111:DJ533_RS13555
uniprot id: A0A2S2FGS9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

1871111:DJ533 RS02165
gene id: 1871111:DJ533_RS02165
uniprot id: A0A2S2F928
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.
messages: Resistance to Hg(2+) in bacteria appears to be governed by a specialized system which includes mercuric reductase. MerA protein is responsible for volatilizing mercury as Hg(0).

1871111:DJ533 RS12340
gene id: 1871111:DJ533_RS12340
uniprot id: A0A2S2FEC7
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1871111:DJ533 RS13915
gene id: 1871111:DJ533_RS13915
uniprot id: A0A2S2FF56
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1871111:DJ533 RS17750
gene id: 1871111:DJ533_RS17750
uniprot id: A0A2S2FHA4
names: Cofactor
names: Similarity
messages: Belongs to the UPF0313 family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

1871111:DJ533 RS06175
gene id: 1871111:DJ533_RS06175
uniprot id: A0A2S2FB53
names: Similarity
messages: Belongs to the YkuD family.

1871111:DJ533 RS08320
gene id: 1871111:DJ533_RS08320
uniprot id: A0A2S2FC70
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Cell membrane
messages: Membrane
messages: Responsible for the transport of dicarboxylates such as succinate, fumarate, and malate across the membrane.

1871111:DJ533 RS15300
gene id: 1871111:DJ533_RS15300
uniprot id: A0A2S2FG06
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

1871111:DJ533 RS03980
gene id: 1871111:DJ533_RS03980
uniprot id: A0A2S2FA32
names: Subcellular Location Annotation
messages: Membrane

1871111:DJ533 RS15390
gene id: 1871111:DJ533_RS15390
uniprot id: A0A2S2FFU6
names: Cofactor
names: Similarity
messages: Belongs to the RtcB family.
messages: Binds 2 manganese ions per subunit.

1871111:DJ533 RS15800
gene id: 1871111:DJ533_RS15800
uniprot id: A0A2S2FG60
names: Subcellular Location Annotation
messages: Membrane

1871111:DJ533 RS15530
gene id: 1871111:DJ533_RS15530
uniprot id: A0A2S2FFW9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

1871111:DJ533 RS12180
gene id: 1871111:DJ533_RS12180
uniprot id: A0A2S2FE78
names: Similarity
messages: Belongs to the group II decarboxylase family.

1871111:DJ533 RS03825
gene id: 1871111:DJ533_RS03825
uniprot id: A0A2S2FBU2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit F family.
messages: Cell membrane
messages: Membrane

1871111:DJ533 RS18485
gene id: 1871111:DJ533_RS18485
uniprot id: A0A2S2FI10
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TerC family.
messages: Membrane

1871111:DJ533 RS13655
gene id: 1871111:DJ533_RS13655
uniprot id: A0A2S2FF00
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

1871111:DJ533 RS11160
gene id: 1871111:DJ533_RS11160
uniprot id: A0A2S2FDS1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IspF family.
messages: Binds 1 divalent metal cation per subunit.
messages: Homotrimer.
messages: Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1871111:DJ533 RS02600
gene id: 1871111:DJ533_RS02600
uniprot id: A0A2S2F9C0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Aromatic acid:H(+) symporter (AAHS) (TC 2.A.1.15) family.
messages: Membrane

1871111:DJ533 RS15815
gene id: 1871111:DJ533_RS15815
uniprot id: A0A2S2FG29
names: Function
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

1871111:DJ533 RS08955
gene id: 1871111:DJ533_RS08955
uniprot id: A0A2S2FCH8
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit B family.

1871111:DJ533 RS08490
gene id: 1871111:DJ533_RS08490
uniprot id: A0A2S2FCB2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with (2E,6E)-farnesyl diphosphate (E,E-FPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E,38E)-undecaprenyl diphosphate (di-trans,octa-cis-UPP). UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide.
messages: Homodimer.

1871111:DJ533 RS15265
gene id: 1871111:DJ533_RS15265
uniprot id: A0A2S2FFT2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L/F-transferase family.
messages: Cytoplasm
messages: Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.

1871111:DJ533 RS18435
gene id: 1871111:DJ533_RS18435
uniprot id: A0A2S2FHF8
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

1871111:DJ533 RS18480
gene id: 1871111:DJ533_RS18480
uniprot id: A0A2S2FHI4
names: Subcellular Location Annotation
messages: Membrane

1871111:DJ533 RS06910
gene id: 1871111:DJ533_RS06910
uniprot id: A0A2S2FBG2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TolB family.
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: Periplasm
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

1871111:DJ533 RS08510
gene id: 1871111:DJ533_RS08510
uniprot id: A0A2S2FCI1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamA family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

1871111:DJ533 RS08380
gene id: 1871111:DJ533_RS08380
uniprot id: A0A2S2FC89
names: Subcellular Location Annotation
messages: Membrane

1871111:DJ533 RS02635
gene id: 1871111:DJ533_RS02635
uniprot id: A0A2S2F9C7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Cytoplasm
messages: Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.

1871111:DJ533 RS07225
gene id: 1871111:DJ533_RS07225
uniprot id: A0A2S2FBN2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transglycosylase Slt family.
messages: Cell outer membrane
messages: Membrane

1871111:DJ533 RS13880
gene id: 1871111:DJ533_RS13880
uniprot id: A0A2S2FFA9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LolA family.
messages: Monomer.
messages: Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane).
messages: Periplasm

1871111:DJ533 RS08045
gene id: 1871111:DJ533_RS08045
uniprot id: A0A2S2FC92
names: Cofactor
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.
messages: Binds 1 [4Fe-4S] cluster per subunit.

1871111:DJ533 RS10965
gene id: 1871111:DJ533_RS10965
uniprot id: A0A2S2FDL9
names: Function
names: PTM
names: Similarity
messages: An intermediate of this reaction is the autophosphorylated ppk in which a phosphate is covalently linked to a histidine residue through a N-P bond.
messages: Belongs to the polyphosphate kinase 1 (PPK1) family.
messages: Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP).

1871111:DJ533 RS13390
gene id: 1871111:DJ533_RS13390
uniprot id: A0A2S2FEV0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family. QueF type 2 subfamily.
messages: Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
messages: Cytoplasm
messages: Homodimer.

1871111:DJ533 RS15550
gene id: 1871111:DJ533_RS15550
uniprot id: A0A2S2FGH0
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity.

1871111:DJ533 RS02210
gene id: 1871111:DJ533_RS02210
uniprot id: A0A2S2F953
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

1871111:DJ533 RS04855
gene id: 1871111:DJ533_RS04855
uniprot id: A0A2S2FAG9
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPAT/DAPAT family.
messages: Cell membrane
messages: The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate.

1871111:DJ533 RS09485
gene id: 1871111:DJ533_RS09485
uniprot id: A0A2S2FCT1
names: Similarity
messages: Belongs to the glycosyl hydrolase 24 family.

1871111:DJ533 RS17670
gene id: 1871111:DJ533_RS17670
uniprot id: A0A2S2FH35
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

1871111:DJ533 RS14595
gene id: 1871111:DJ533_RS14595
uniprot id: A0A2S2FFH7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transpeptidase family. MrdA subfamily.
messages: Catalyzes cross-linking of the peptidoglycan cell wall.
messages: Cell inner membrane

1871111:DJ533 RS08655
gene id: 1871111:DJ533_RS08655
uniprot id: A0A2S2FCD0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RlmKL family.
messages: Cytoplasm
messages: Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA.

1871111:DJ533 RS00550
gene id: 1871111:DJ533_RS00550
uniprot id: A0A2S2F8H3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

1871111:DJ533 RS18275
gene id: 1871111:DJ533_RS18275
uniprot id: A0A2S2FHC0
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1871111:DJ533 RS09365
gene id: 1871111:DJ533_RS09365
uniprot id: A0A2S2FD89
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

1871111:DJ533 RS05855
gene id: 1871111:DJ533_RS05855
uniprot id: A0A2S2FB08
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

1871111:DJ533 RS16135
gene id: 1871111:DJ533_RS16135
uniprot id: A0A2S2FGF8
names: Similarity
messages: Belongs to the YciI family.

1871111:DJ533 RS08020
gene id: 1871111:DJ533_RS08020
uniprot id: A0A2S2FC17
names: Subcellular Location Annotation
messages: Membrane

1871111:DJ533 RS11535
gene id: 1871111:DJ533_RS11535
uniprot id: A0A2S2FDV2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

1871111:DJ533 RS18505
gene id: 1871111:DJ533_RS18505
uniprot id: A0A2S2FHN1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

1871111:DJ533 RS01085
gene id: 1871111:DJ533_RS01085
uniprot id: A0A2S2F8M3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

1871111:DJ533 RS08105
gene id: 1871111:DJ533_RS08105
uniprot id: A0A2S2FC51
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

1871111:DJ533 RS14750
gene id: 1871111:DJ533_RS14750
uniprot id: A0A2S2FFK3
names: Similarity
messages: Belongs to the fabD family.

1871111:DJ533 RS05545
gene id: 1871111:DJ533_RS05545
uniprot id: A0A2S2FBA4
names: Cofactor
names: Similarity
messages: Belongs to the monomeric-type IDH family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

1871111:DJ533 RS14815
gene id: 1871111:DJ533_RS14815
uniprot id: A0A2S2FFR6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dethiobiotin synthetase family.
messages: Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1871111:DJ533 RS07430
gene id: 1871111:DJ533_RS07430
uniprot id: A0A2S2FBR9
names: Function
messages: Involved in the transposition of the insertion sequence.

1871111:DJ533 RS11815
gene id: 1871111:DJ533_RS11815
uniprot id: A0A2S2FEH3
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family.

1871111:DJ533 RS17485
gene id: 1871111:DJ533_RS17485
uniprot id: A0A2S2FGX8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0126 family.
messages: Membrane

1871111:DJ533 RS15770
gene id: 1871111:DJ533_RS15770
uniprot id: A0A2S2FG78
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

1871111:DJ533 RS07400
gene id: 1871111:DJ533_RS07400
uniprot id: A0A2S2FDM6
names: Function
messages: TetR is the repressor of the tetracycline resistance element; its N-terminal region forms a helix-turn-helix structure and binds DNA. Binding of tetracycline to TetR reduces the repressor affinity for the tetracycline resistance gene (tetA) promoter operator sites.

1871111:DJ533 RS12890
gene id: 1871111:DJ533_RS12890
uniprot id: A0A2S2FEP1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.
messages: Cytoplasm
messages: May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.

1871111:DJ533 RS05560
gene id: 1871111:DJ533_RS05560
uniprot id: A0A2S2FB12
names: Function
names: Similarity
messages: Acts on leucine, isoleucine and valine.
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

1871111:DJ533 RS13175
gene id: 1871111:DJ533_RS13175
uniprot id: A0A2S2FER5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAPS reductase family. CysH subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of sulfite from adenosine 5'-phosphosulfate (APS) using thioredoxin as an electron donor.
messages: Cytoplasm

1871111:DJ533 RS14105
gene id: 1871111:DJ533_RS14105
uniprot id: A0A2S2FF84
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1871111:DJ533 RS18550
gene id: 1871111:DJ533_RS18550
uniprot id: A0A2S2FHH0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0161 family.
messages: Cell membrane
messages: Could be involved in insertion of integral membrane proteins into the membrane.

1871111:DJ533 RS04430
gene id: 1871111:DJ533_RS04430
uniprot id: A0A2S2FA89
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the C-terminal section; belongs to the PRA-PH family.
messages: In the N-terminal section; belongs to the PRA-CH family.

1871111:DJ533 RS13135
gene id: 1871111:DJ533_RS13135
uniprot id: A0A2S2FF87
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer.

1871111:DJ533 RS06285
gene id: 1871111:DJ533_RS06285
uniprot id: A0A2S2FD33
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 3 family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1871111:DJ533 RS09900
gene id: 1871111:DJ533_RS09900
uniprot id: A0A2S2FJG3
names: Cofactor
names: Similarity
messages: Belongs to the RtcB family.
messages: Binds 2 manganese ions per subunit.

1871111:DJ533 RS18285
gene id: 1871111:DJ533_RS18285
uniprot id: A0A2S2FHC2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PEPCase type 1 family.
messages: Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.
messages: Homotetramer.

1871111:DJ533 RS08175
gene id: 1871111:DJ533_RS08175
uniprot id: A0A2S2FC47
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DEAD box helicase family. RhlB subfamily.
messages: Component of the RNA degradosome, which is a multiprotein complex involved in RNA processing and mRNA degradation.
messages: Cytoplasm
messages: DEAD-box RNA helicase involved in RNA degradation. Has RNA-dependent ATPase activity and unwinds double-stranded RNA.

1871111:DJ533 RS09725
gene id: 1871111:DJ533_RS09725
uniprot id: A0A2S2FES6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

1871111:DJ533 RS17590
gene id: 1871111:DJ533_RS17590
uniprot id: A0A2S2FH63
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1871111:DJ533 RS09130
gene id: 1871111:DJ533_RS09130
uniprot id: A0A2S2FCM1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Cell membrane
messages: Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system).
messages: Membrane

1871111:DJ533 RS05230
gene id: 1871111:DJ533_RS05230
uniprot id: A0A2S2FAN8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methylthiotransferase family. MiaB subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
messages: Cytoplasm
messages: Monomer.

1871111:DJ533 RS17505
gene id: 1871111:DJ533_RS17505
uniprot id: A0A2S2FHG5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane
messages: Membrane

1871111:DJ533 RS09010
gene id: 1871111:DJ533_RS09010
uniprot id: A0A2S2FCJ1
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

1871111:DJ533 RS03540
gene id: 1871111:DJ533_RS03540
uniprot id: A0A2S2FBP6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Membrane

1871111:DJ533 RS05635
gene id: 1871111:DJ533_RS05635
uniprot id: A0A2S2FAW8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1871111:DJ533 RS16495
gene id: 1871111:DJ533_RS16495
uniprot id: A0A2S2FGM3
names: Function
names: Similarity
messages: Belongs to the dihydrofolate reductase family.
messages: Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.

1871111:DJ533 RS04090
gene id: 1871111:DJ533_RS04090
uniprot id: A0A2S2FA51
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

1871111:DJ533 RS07205
gene id: 1871111:DJ533_RS07205
uniprot id: A0A2S2FBU7
names: Similarity
messages: Belongs to the transglycosylase Slt family.

1871111:DJ533 RS15975
gene id: 1871111:DJ533_RS15975
uniprot id: A0A2S2FHX0
names: Similarity
messages: Belongs to the YggT family.

1871111:DJ533 RS13200
gene id: 1871111:DJ533_RS13200
uniprot id: A0A2S2FEY0
names: Function
names: Similarity
messages: Belongs to the MreC family.
messages: Involved in formation and maintenance of cell shape.

1871111:DJ533 RS16940
gene id: 1871111:DJ533_RS16940
uniprot id: A0A2S2FHV8
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

1871111:DJ533 RS06825
gene id: 1871111:DJ533_RS06825
uniprot id: A0A2S2FDC2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Membrane

1871111:DJ533 RS08505
gene id: 1871111:DJ533_RS08505
uniprot id: A0A2S2FCA3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

1871111:DJ533 RS02050
gene id: 1871111:DJ533_RS02050
uniprot id: A0A2S2F921
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1871111:DJ533 RS06975
gene id: 1871111:DJ533_RS06975
uniprot id: A0A2S2FBQ8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1871111:DJ533 RS01880
gene id: 1871111:DJ533_RS01880
uniprot id: A0A2S2FB16
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

1871111:DJ533 RS06585
gene id: 1871111:DJ533_RS06585
uniprot id: A0A2S2FBI3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LolB family.
messages: Cell outer membrane
messages: Membrane
messages: Monomer.

1871111:DJ533 RS11040
gene id: 1871111:DJ533_RS11040
uniprot id: A0A2S2FDL4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal stress protein A family.
messages: Cytoplasm

1871111:DJ533 RS09135
gene id: 1871111:DJ533_RS09135
uniprot id: A0A2S2FEH4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Membrane

1871111:DJ533 RS06970
gene id: 1871111:DJ533_RS06970
uniprot id: A0A2S2FBH9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HflD family.
messages: Cell membrane
messages: Cytoplasm

1871111:DJ533 RS04205
gene id: 1871111:DJ533_RS04205
uniprot id: A0A2S2FAB1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.
messages: Cell inner membrane
messages: Membrane
messages: Probable transporter of a GTP-driven Fe(2+) uptake system.

1871111:DJ533 RS06920
gene id: 1871111:DJ533_RS06920
uniprot id: A0A2S2FBG7
names: Function
names: Similarity
messages: Belongs to the peptidase S11 family.
messages: Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors.

1871111:DJ533 RS04325
gene id: 1871111:DJ533_RS04325
uniprot id: A0A2S2FAD0
names: Similarity
messages: Belongs to the GSP N family.

1871111:DJ533 RS08840
gene id: 1871111:DJ533_RS08840
uniprot id: A0A2S2FCH5
names: Similarity
messages: Belongs to the IMPACT family.

1871111:DJ533 RS15410
gene id: 1871111:DJ533_RS15410
uniprot id: A0A2S2FG26
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1871111:DJ533 RS05815
gene id: 1871111:DJ533_RS05815
uniprot id: A0A2S2FBF2
names: Subcellular Location Annotation
messages: Membrane

1871111:DJ533 RS04815
gene id: 1871111:DJ533_RS04815
uniprot id: A0A2S2FAH5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Membrane

1871111:DJ533 RS18320
gene id: 1871111:DJ533_RS18320
uniprot id: A0A2S2FHJ5
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

1871111:DJ533 RS16745
gene id: 1871111:DJ533_RS16745
uniprot id: A0A2S2FGR1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.

1871111:DJ533 RS03070
gene id: 1871111:DJ533_RS03070
uniprot id: A0A2S2F9J7
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

1871111:DJ533 RS14215
gene id: 1871111:DJ533_RS14215
uniprot id: A0A2S2FF97
names: Similarity
messages: Belongs to the UbiH/COQ6 family.

1871111:DJ533 RS11225
gene id: 1871111:DJ533_RS11225
uniprot id: A0A2S2FDP8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

1871111:DJ533 RS05475
gene id: 1871111:DJ533_RS05475
uniprot id: A0A2S2FHM6
names: Similarity
messages: Belongs to the TrpF family.

1871111:DJ533 RS03000
gene id: 1871111:DJ533_RS03000
uniprot id: A0A2S2FBG4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

1871111:DJ533 RS15980
gene id: 1871111:DJ533_RS15980
uniprot id: A0A2S2FG65
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

1871111:DJ533 RS06720
gene id: 1871111:DJ533_RS06720
uniprot id: A0A2S2FBE5
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

1871111:DJ533 RS11610
gene id: 1871111:DJ533_RS11610
uniprot id: A0A2S2FE27
names: Similarity
messages: Belongs to the bacterial ring-hydroxylating dioxygenase beta subunit family.

1871111:DJ533 RS04185
gene id: 1871111:DJ533_RS04185
uniprot id: A0A2S2FA50
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

1871111:DJ533 RS04995
gene id: 1871111:DJ533_RS04995
uniprot id: A0A2S2FAH4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

1871111:DJ533 RS07590
gene id: 1871111:DJ533_RS07590
uniprot id: A0A2S2FCB5
names: Similarity
messages: Belongs to the TelA family.

1871111:DJ533 RS09355
gene id: 1871111:DJ533_RS09355
uniprot id: A0A2S2FCR5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

1871111:DJ533 RS02780
gene id: 1871111:DJ533_RS02780
uniprot id: A0A2S2F9L6
names: Similarity
messages: Belongs to the SAICAR synthetase family.

1871111:DJ533 RS03795
gene id: 1871111:DJ533_RS03795
uniprot id: A0A2S2FA11
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
messages: Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).
messages: Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1871111:DJ533 RS10900
gene id: 1871111:DJ533_RS10900
uniprot id: A0A2S2FDJ2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. SRP is a ribonucleoprotein composed of Ffh and a 4.5S RNA molecule.

1871111:DJ533 RS08205
gene id: 1871111:DJ533_RS08205
uniprot id: A0A2S2FC75
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1871111:DJ533 RS13470
gene id: 1871111:DJ533_RS13470
uniprot id: A0A2S2FEX8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1871111:DJ533 RS03830
gene id: 1871111:DJ533_RS03830
uniprot id: A0A2S2F9X7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit E family.
messages: Cell membrane
messages: Membrane

1871111:DJ533 RS07920
gene id: 1871111:DJ533_RS07920
uniprot id: A0A2S2FCH4
names: Function
names: Similarity
messages: Belongs to the DHNA family.
messages: Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin.

1871111:DJ533 RS18060
gene id: 1871111:DJ533_RS18060
uniprot id: A0A2S2FH81
names: Subcellular Location Annotation
messages: Membrane

1871111:DJ533 RS17185
gene id: 1871111:DJ533_RS17185
uniprot id: A0A2S2FH00
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1871111:DJ533 RS03535
gene id: 1871111:DJ533_RS03535
uniprot id: A0A2S2F9S3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase A chain family.
messages: Cell membrane
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

1871111:DJ533 RS01720
gene id: 1871111:DJ533_RS01720
uniprot id: A0A2S2F978
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

1871111:DJ533 RS11565
gene id: 1871111:DJ533_RS11565
uniprot id: A0A2S2FDZ9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptD family.
messages: Cell outer membrane
messages: Component of the lipopolysaccharide transport and assembly complex. Interacts with LptE and LptA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane.

1871111:DJ533 RS11575
gene id: 1871111:DJ533_RS11575
uniprot id: A0A2S2FDV7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Hfq family.
messages: Homohexamer.
messages: RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs.

1871111:DJ533 RS04275
gene id: 1871111:DJ533_RS04275
uniprot id: A0A2S2FC22
names: Function
names: Similarity
messages: Belongs to the Fe(2+)-trafficking protein family.
messages: Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes.

1871111:DJ533 RS03075
gene id: 1871111:DJ533_RS03075
uniprot id: A0A2S2F9M3
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

1871111:DJ533 RS07900
gene id: 1871111:DJ533_RS07900
uniprot id: A0A2S2FBZ2
names: Similarity
messages: Belongs to the prokaryotic/mitochondrial release factor family.

1871111:DJ533 RS02465
gene id: 1871111:DJ533_RS02465
uniprot id: A0A2S2F927
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1871111:DJ533 RS18555
gene id: 1871111:DJ533_RS18555
uniprot id: A0A2S2FHP5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RnpA family.
messages: Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.
messages: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.

1871111:DJ533 RS06335
gene id: 1871111:DJ533_RS06335
uniprot id: A0A2S2FD43
names: Subcellular Location Annotation
messages: Membrane

1871111:DJ533 RS03730
gene id: 1871111:DJ533_RS03730
uniprot id: A0A2S2FA02
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

1871111:DJ533 RS16310
gene id: 1871111:DJ533_RS16310
uniprot id: A0A2S2FGC5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

1871111:DJ533 RS15585
gene id: 1871111:DJ533_RS15585
uniprot id: A0A2S2FHP8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

1871111:DJ533 RS15195
gene id: 1871111:DJ533_RS15195
uniprot id: A0A2S2FFY5
names: Caution
names: Function
names: Similarity
messages: Belongs to the dUTPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

1871111:DJ533 RS15590
gene id: 1871111:DJ533_RS15590
uniprot id: A0A2S2FFZ4
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

1871111:DJ533 RS04970
gene id: 1871111:DJ533_RS04970
uniprot id: A0A2S2FAJ5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

1871111:DJ533 RS02125
gene id: 1871111:DJ533_RS02125
uniprot id: A0A2S2FAX3
names: Function
messages: Involved in the transposition of the insertion sequence.

1871111:DJ533 RS06550
gene id: 1871111:DJ533_RS06550
uniprot id: A0A2S2FHT0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

1871111:DJ533 RS17520
gene id: 1871111:DJ533_RS17520
uniprot id: A0A2S2FH61
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transpeptidase family. FtsI subfamily.
messages: Catalyzes cross-linking of the peptidoglycan cell wall at the division septum.
messages: Cell inner membrane

1871111:DJ533 RS00530
gene id: 1871111:DJ533_RS00530
uniprot id: A0A2S2F8R0
names: Similarity
messages: Belongs to the MobA/MobL family.

1871111:DJ533 RS04520
gene id: 1871111:DJ533_RS04520
uniprot id: A0A2S2FC65
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

1871111:DJ533 RS07675
gene id: 1871111:DJ533_RS07675
uniprot id: A0A2S2FDS3
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1871111:DJ533 RS05020
gene id: 1871111:DJ533_RS05020
uniprot id: A0A2S2FAL1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

1871111:DJ533 RS13610
gene id: 1871111:DJ533_RS13610
uniprot id: A0A2S2FGT4
names: Similarity
messages: Belongs to the FAD-dependent oxidoreductase family.

1871111:DJ533 RS16525
gene id: 1871111:DJ533_RS16525
uniprot id: A0A2S2FGH3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane
messages: Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins.

1871111:DJ533 RS11105
gene id: 1871111:DJ533_RS11105
uniprot id: A0A2S2FDR0
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 2 residues (Tyr-53 and Arg-56) present in a large hydrophobic pocket are probably involved in substrate specificity. They are important for desuccinylation activity, but dispensable for deacetylation activity.
messages: Belongs to the sirtuin family. Class III subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form.

1871111:DJ533 RS11140
gene id: 1871111:DJ533_RS11140
uniprot id: A0A2S2FDN7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1871111:DJ533 RS15600
gene id: 1871111:DJ533_RS15600
uniprot id: A0A2S2FGI0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm

1871111:DJ533 RS16755
gene id: 1871111:DJ533_RS16755
uniprot id: A0A2S2FIB5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 1 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

1871111:DJ533 RS09690
gene id: 1871111:DJ533_RS09690
uniprot id: A0A2S2FDE6
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

1871111:DJ533 RS12325
gene id: 1871111:DJ533_RS12325
uniprot id: A0A2S2FEA1
names: Subcellular Location Annotation
messages: Membrane

1871111:DJ533 RS14355
gene id: 1871111:DJ533_RS14355
uniprot id: A0A2S2FH50
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nicotinamide ribonucleoside (NR) uptake permease (TC 4.B.1) family.
messages: Membrane
messages: Required for nicotinamide riboside transport across the inner membrane.

1871111:DJ533 RS02410
gene id: 1871111:DJ533_RS02410
uniprot id: A0A2S2F8V9
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1871111:DJ533 RS11065
gene id: 1871111:DJ533_RS11065
uniprot id: A0A2S2FDL5
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmB subfamily.
messages: Methylates ribosomal protein uL3 on a specific glutamine residue.

1871111:DJ533 RS00875
gene id: 1871111:DJ533_RS00875
uniprot id: A0A2S2F8T3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone-like protein H-NS family.
messages: nucleoid

1871111:DJ533 RS04170
gene id: 1871111:DJ533_RS04170
uniprot id: A0A2S2FA35
names: Similarity
messages: Belongs to the peptidase S11 family.

1871111:DJ533 RS03475
gene id: 1871111:DJ533_RS03475
uniprot id: A0A2S2F9U2
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.
messages: Homotetramer.

1871111:DJ533 RS14910
gene id: 1871111:DJ533_RS14910
uniprot id: A0A2S2FFU1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. SRP is a ribonucleoprotein composed of Ffh and a 4.5S RNA molecule.

1871111:DJ533 RS15735
gene id: 1871111:DJ533_RS15735
uniprot id: A0A2S2FHS7
names: Function
names: Similarity
messages: Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control.
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

1871111:DJ533 RS07840
gene id: 1871111:DJ533_RS07840
uniprot id: A0A2S2FDV0
names: Similarity
messages: Belongs to the YkuD family.

1871111:DJ533 RS17345
gene id: 1871111:DJ533_RS17345
uniprot id: A0A2S2FH26
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

1871111:DJ533 RS07095
gene id: 1871111:DJ533_RS07095
uniprot id: A0A2S2FBJ6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1871111:DJ533 RS07395
gene id: 1871111:DJ533_RS07395
uniprot id: A0A2S2FBQ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. TCR/Tet family.
messages: Membrane
messages: Resistance to tetracycline by an active tetracycline efflux. This is an energy-dependent process that decreases the accumulation of the antibiotic in whole cells. This protein functions as a metal-tetracycline/H(+) antiporter.

1871111:DJ533 RS18105
gene id: 1871111:DJ533_RS18105
uniprot id: A0A2S2FHF7
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

1871111:DJ533 RS04595
gene id: 1871111:DJ533_RS04595
uniprot id: A0A2S2FAD7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CN hydrolase family. Apolipoprotein N-acyltransferase subfamily.
messages: Catalyzes the phospholipid dependent N-acylation of the N-terminal cysteine of apolipoprotein, the last step in lipoprotein maturation.
messages: Cell membrane
messages: Membrane

1871111:DJ533 RS03755
gene id: 1871111:DJ533_RS03755
uniprot id: A0A2S2FA31
names: Similarity
messages: Belongs to the UPF0053 family.

1871111:DJ533 RS11810
gene id: 1871111:DJ533_RS11810
uniprot id: A0A2S2FE24
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1871111:DJ533 RS13570
gene id: 1871111:DJ533_RS13570
uniprot id: A0A2S2FFG1
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

1871111:DJ533 RS09780
gene id: 1871111:DJ533_RS09780
uniprot id: A0A2S2FD76
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.

1871111:DJ533 RS14305
gene id: 1871111:DJ533_RS14305
uniprot id: A0A2S2FFB7
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

1871111:DJ533 RS13165
gene id: 1871111:DJ533_RS13165
uniprot id: A0A2S2FEQ6
names: Subcellular Location Annotation
messages: Membrane

1871111:DJ533 RS10785
gene id: 1871111:DJ533_RS10785
uniprot id: A0A2S2FDP9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1871111:DJ533 RS04560
gene id: 1871111:DJ533_RS04560
uniprot id: A0A2S2FAH1
names: Similarity
messages: Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family.

1871111:DJ533 RS02805
gene id: 1871111:DJ533_RS02805
uniprot id: A0A2S2F9Y9
names: Subcellular Location Annotation
messages: Membrane

1871111:DJ533 RS16815
gene id: 1871111:DJ533_RS16815
uniprot id: A0A2S2FGN8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1871111:DJ533 RS02510
gene id: 1871111:DJ533_RS02510
uniprot id: A0A1P8L0B2
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Binds two Mg(2+) per subunit. The magnesium ions form salt bridges with both the protein and the DNA. Can also accept other divalent metal cations, such as Mn(2+) or Ca(2+).
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

1871111:DJ533 RS16025
gene id: 1871111:DJ533_RS16025
uniprot id: A0A2S2FHY1
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1871111:DJ533 RS10220
gene id: 1871111:DJ533_RS10220
uniprot id: A0A2S2FD61
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1871111:DJ533 RS02545
gene id: 1871111:DJ533_RS02545
uniprot id: A0A2S2F9B2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HesB/IscA family.
messages: Binds 1 iron-sulfur cluster per subunit.
messages: Homodimer.
messages: Required for insertion of 4Fe-4S clusters for at least IspG.

1871111:DJ533 RS05505
gene id: 1871111:DJ533_RS05505
uniprot id: A0A2S2FAU9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the diaminopimelate dehydrogenase family.
messages: Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L-tetrahydrodipicolinate, to generate the meso compound, D,L-2,6-diaminopimelate.
messages: Homodimer.

1871111:DJ533 RS18135
gene id: 1871111:DJ533_RS18135
uniprot id: A0A2S2FHA7
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

1871111:DJ533 RS09880
gene id: 1871111:DJ533_RS09880
uniprot id: A0A2S2FCZ9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KdpA family.
messages: Cell membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds the extracellular potassium ions and delivers the ions to the membrane domain of KdpB through an intramembrane tunnel.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

1871111:DJ533 RS04315
gene id: 1871111:DJ533_RS04315
uniprot id: A0A2S2FAF4
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

1871111:DJ533 RS09865
gene id: 1871111:DJ533_RS09865
uniprot id: A0A2S2FD14
names: Subcellular Location Annotation
messages: Membrane

1871111:DJ533 RS16005
gene id: 1871111:DJ533_RS16005
uniprot id: A0A2S2FGD5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.

1871111:DJ533 RS09885
gene id: 1871111:DJ533_RS09885
uniprot id: A0A2S2FD74
names: Similarity
messages: Belongs to the peptidase M1 family.

1871111:DJ533 RS08400
gene id: 1871111:DJ533_RS08400
uniprot id: A0A2S2FC84
names: Similarity
messages: Belongs to the UPF0053 family.

1871111:DJ533 RS14265
gene id: 1871111:DJ533_RS14265
uniprot id: A0A2S2FFU0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

1871111:DJ533 RS03025
gene id: 1871111:DJ533_RS03025
uniprot id: A0A2S2F9L4
names: Function
names: Similarity
messages: Belongs to the LpxC family.
messages: Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.

1871111:DJ533 RS09165
gene id: 1871111:DJ533_RS09165
uniprot id: A0A2S2FCM0
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

1871111:DJ533 RS06055
gene id: 1871111:DJ533_RS06055
uniprot id: A0A2S2FB31
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmJ family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the guanosine in position 1516 of 16S rRNA.

1871111:DJ533 RS05275
gene id: 1871111:DJ533_RS05275
uniprot id: A0A2S2FCL3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

1871111:DJ533 RS04220
gene id: 1871111:DJ533_RS04220
uniprot id: A0A2S2FA47
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEDS family. FtsW subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Peptidoglycan polymerase that is essential for cell division.

1871111:DJ533 RS04990
gene id: 1871111:DJ533_RS04990
uniprot id: A0A2S2FAP9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

1871111:DJ533 RS12275
gene id: 1871111:DJ533_RS12275
uniprot id: A0A2S2FE94
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.
messages: Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA.
messages: Cytoplasm
messages: Homodimer.

1871111:DJ533 RS13445
gene id: 1871111:DJ533_RS13445
uniprot id: A0A2S2FGQ9
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

1871111:DJ533 RS05735
gene id: 1871111:DJ533_RS05735
uniprot id: A0A2S2FAX7
names: Subcellular Location Annotation
messages: Membrane

1871111:DJ533 RS07230
gene id: 1871111:DJ533_RS07230
uniprot id: A0A2S2FBP0
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family. GreB subfamily.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length.

1871111:DJ533 RS05025
gene id: 1871111:DJ533_RS05025
uniprot id: A0A2S2FAK6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

1871111:DJ533 RS15870
gene id: 1871111:DJ533_RS15870
uniprot id: A0A2S2FG53
names: Similarity
messages: Belongs to the thioredoxin family.

1871111:DJ533 RS08605
gene id: 1871111:DJ533_RS08605
uniprot id: A0A2S2FCD1
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1871111:DJ533 RS15660
gene id: 1871111:DJ533_RS15660
uniprot id: A0A2S2FFZ7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

1871111:DJ533 RS04400
gene id: 1871111:DJ533_RS04400
uniprot id: A0A2S2FAE0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

1871111:DJ533 RS04145
gene id: 1871111:DJ533_RS04145
uniprot id: A0A2S2FA58
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the BPG-independent phosphoglycerate mutase family.
messages: Binds 2 manganese ions per subunit.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: Monomer.

1871111:DJ533 RS17920
gene id: 1871111:DJ533_RS17920
uniprot id: A0A2S2FH77
names: Function
messages: This protein is a positive regulator for the phosphate regulon. Transcription of this operon is positively regulated by PhoB and PhoR when phosphate is limited.

1871111:DJ533 RS10960
gene id: 1871111:DJ533_RS10960
uniprot id: A0A2S2FDK2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. Biotin synthase family.
messages: Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
messages: Homodimer.

1871111:DJ533 RS15755
gene id: 1871111:DJ533_RS15755
uniprot id: A0A2S2FG32
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

1871111:DJ533 RS18165
gene id: 1871111:DJ533_RS18165
uniprot id: A0A2S2FJ21
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase PH family.
messages: Homohexameric ring arranged as a trimer of dimers.
messages: Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.

1871111:DJ533 RS10015
gene id: 1871111:DJ533_RS10015
uniprot id: A0A2S2FD29
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1871111:DJ533 RS14520
gene id: 1871111:DJ533_RS14520
uniprot id: A0A2S2FFF4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

1871111:DJ533 RS03405
gene id: 1871111:DJ533_RS03405
uniprot id: A0A2S2F9Q9
names: Caution
names: Function
names: PTM
names: Similarity
messages: Acetylated. Deacetylation by the SIR2-homolog deacetylase activates the enzyme.
messages: Belongs to the ATP-dependent AMP-binding enzyme family.
messages: Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1871111:DJ533 RS05870
gene id: 1871111:DJ533_RS05870
uniprot id: A0A2S2FAZ4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the quinolinate synthase family. Type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
messages: Cytoplasm

1871111:DJ533 RS12290
gene id: 1871111:DJ533_RS12290
uniprot id: A0A2S2FEB5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the uroporphyrinogen decarboxylase family.
messages: Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1871111:DJ533 RS10245
gene id: 1871111:DJ533_RS10245
uniprot id: A0A2S2FF20
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AzlC family.
messages: Membrane

1871111:DJ533 RS04570
gene id: 1871111:DJ533_RS04570
uniprot id: A0A2S2FC74
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Cell inner membrane
messages: Component of the type II secretion system inner membrane complex required for the energy-dependent secretion of extracellular factors such as proteases and toxins from the periplasm.
messages: Membrane

1871111:DJ533 RS04625
gene id: 1871111:DJ533_RS04625
uniprot id: A0A2S2FC86
names: Function
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.
messages: Provides the (R)-glutamate required for cell wall biosynthesis.

1871111:DJ533 RS17715
gene id: 1871111:DJ533_RS17715
uniprot id: A0A2S2FH19
names: Subcellular Location Annotation
messages: Membrane

1871111:DJ533 RS08485
gene id: 1871111:DJ533_RS08485
uniprot id: A0A2S2FCA9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

1871111:DJ533 RS09215
gene id: 1871111:DJ533_RS09215
uniprot id: A0A2S2FD56
names: Function
names: Similarity
messages: Belongs to the CobU/CobP family.
messages: Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate.

1871111:DJ533 RS18025
gene id: 1871111:DJ533_RS18025
uniprot id: A0A2S2FHR6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm

1871111:DJ533 RS04755
gene id: 1871111:DJ533_RS04755
uniprot id: A0A2S2FHS0
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Monomer.

1871111:DJ533 RS03150
gene id: 1871111:DJ533_RS03150
uniprot id: A0A2S2F9L1
names: Similarity
messages: Belongs to the pirin family.

1871111:DJ533 RS05865
gene id: 1871111:DJ533_RS05865
uniprot id: A0A2S2FBF9
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArgJ family.
messages: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.
messages: Cytoplasm
messages: Heterotetramer of two alpha and two beta chains.
messages: Some bacteria possess a monofunctional ArgJ, i.e., capable of catalyzing only the fifth step of the arginine biosynthetic pathway.

1871111:DJ533 RS10125
gene id: 1871111:DJ533_RS10125
uniprot id: A0A2S2FD70
names: Similarity
messages: Belongs to the FMO family.

1871111:DJ533 RS16875
gene id: 1871111:DJ533_RS16875
uniprot id: A0A2S2FGN6
names: Similarity
names: Subunit
messages: Belongs to the LigB/MhpB extradiol dioxygenase family.
messages: Homotetramer.

1871111:DJ533 RS02725
gene id: 1871111:DJ533_RS02725
uniprot id: A0A2S2F9D9
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1871111:DJ533 RS03370
gene id: 1871111:DJ533_RS03370
uniprot id: A0A2S2F9S0
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aquaporins contain two tandem repeats each containing three membrane-spanning domains and a pore-forming loop with the signature motif Asn-Pro-Ala (NPA).
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Cell membrane
messages: Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1871111:DJ533 RS02970
gene id: 1871111:DJ533_RS02970
uniprot id: A0A2S2F9H6
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

1871111:DJ533 RS15790
gene id: 1871111:DJ533_RS15790
uniprot id: A0A2S2FHT8
names: Similarity
messages: Belongs to the hyi family.

1871111:DJ533 RS07485
gene id: 1871111:DJ533_RS07485
uniprot id: A0A2S2FBR3
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

1871111:DJ533 RS03080
gene id: 1871111:DJ533_RS03080
uniprot id: A0A2S2F9U1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the pyridoxamine 5'-phosphate oxidase family.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1871111:DJ533 RS12280
gene id: 1871111:DJ533_RS12280
uniprot id: A0A2S2FG37
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

1871111:DJ533 RS12805
gene id: 1871111:DJ533_RS12805
uniprot id: A0A2S2FGE5
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1871111:DJ533 RS16890
gene id: 1871111:DJ533_RS16890
uniprot id: A0A2S2FGS4
names: Similarity
messages: Belongs to the bacterial ring-hydroxylating dioxygenase beta subunit family.

1871111:DJ533 RS15460
gene id: 1871111:DJ533_RS15460
uniprot id: A0A2S2FI12
names: Subunit
messages: Monomer.

1871111:DJ533 RS05530
gene id: 1871111:DJ533_RS05530
uniprot id: A0A2S2FAU8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.

1871111:DJ533 RS06895
gene id: 1871111:DJ533_RS06895
uniprot id: A0A2S2FBG9
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FBPase class 1 family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1871111:DJ533 RS05415
gene id: 1871111:DJ533_RS05415
uniprot id: A0A2S2FAS5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

1871111:DJ533 RS12165
gene id: 1871111:DJ533_RS12165
uniprot id: A0A2S2FEE3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

1871111:DJ533 RS07935
gene id: 1871111:DJ533_RS07935
uniprot id: A0A2S2FC76
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Cell membrane
messages: Membrane

1871111:DJ533 RS05060
gene id: 1871111:DJ533_RS05060
uniprot id: A0A2S2FAK0
names: Similarity
messages: Belongs to the SdhE FAD assembly factor family.

1871111:DJ533 RS05225
gene id: 1871111:DJ533_RS05225
uniprot id: A0A2S2FAP4
names: Similarity
messages: Belongs to the PhoH family.

1871111:DJ533 RS03595
gene id: 1871111:DJ533_RS03595
uniprot id: A0A2S2F9U0
names: Similarity
messages: Belongs to the class-D beta-lactamase family.

1871111:DJ533 RS05370
gene id: 1871111:DJ533_RS05370
uniprot id: A0A2S2FAQ7
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1871111:DJ533 RS14715
gene id: 1871111:DJ533_RS14715
uniprot id: A0A2S2FFI0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.
messages: Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.
messages: Cytoplasm
messages: Homodimer.

1871111:DJ533 RS06905
gene id: 1871111:DJ533_RS06905
uniprot id: A0A2S2FBZ0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Pal lipoprotein family.
messages: Cell outer membrane
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

1871111:DJ533 RS07810
gene id: 1871111:DJ533_RS07810
uniprot id: A0A2S2FBX1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. PdxB subfamily.
messages: Catalyzes the oxidation of erythronate-4-phosphate to 3-hydroxy-2-oxo-4-phosphonooxybutanoate.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1871111:DJ533 RS13490
gene id: 1871111:DJ533_RS13490
uniprot id: A0A2S2FF43
names: Similarity
messages: Belongs to the peptidase C56 family.

1871111:DJ533 RS02205
gene id: 1871111:DJ533_RS02205
uniprot id: A0A2S2F8Z3
names: Similarity
messages: Belongs to the site-specific recombinase resolvase family.

1871111:DJ533 RS02815
gene id: 1871111:DJ533_RS02815
uniprot id: A0A2S2F9I4
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1871111:DJ533 RS07605
gene id: 1871111:DJ533_RS07605
uniprot id: A0A2S2FC15
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome c oxidase bacterial subunit 4 family.
messages: Cytochrome bo(3) ubiquinol terminal oxidase is the component of the aerobic respiratory chain of E.coli that predominates when cells are grown at high aeration. Has proton pump activity across the membrane in addition to electron transfer, pumping 2 protons/electron.
messages: Heterooctamer of two A chains, two B chains, two C chains and two D chains.
messages: Membrane

1871111:DJ533 RS16290
gene id: 1871111:DJ533_RS16290
uniprot id: A0A2S2FGG8
names: Similarity
messages: Belongs to the peptidase S41A family.

1871111:DJ533 RS07655
gene id: 1871111:DJ533_RS07655
uniprot id: A0A2S2FC25
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. HisZ subfamily.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine.
messages: This function is generally fulfilled by the C-terminal part of HisG, which is missing in some bacteria such as this one.

1871111:DJ533 RS11830
gene id: 1871111:DJ533_RS11830
uniprot id: A0A2S2FE62
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit B family.

1871111:DJ533 RS13090
gene id: 1871111:DJ533_RS13090
uniprot id: A0A2S2FEQ9
names: Similarity
messages: Belongs to the NADH dehydrogenase family.

1871111:DJ533 RS15250
gene id: 1871111:DJ533_RS15250
uniprot id: A0A2S2FFZ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FtsK/SpoIIIE/SftA family.
messages: Membrane

1871111:DJ533 RS18120
gene id: 1871111:DJ533_RS18120
uniprot id: A0A2S2FH89
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the etk/wzc family.
messages: Cell inner membrane
messages: Membrane

1871111:DJ533 RS08060
gene id: 1871111:DJ533_RS08060
uniprot id: A0A2S2FCA1
names: Similarity
messages: Belongs to the MQO family.

1871111:DJ533 RS08390
gene id: 1871111:DJ533_RS08390
uniprot id: A0A2S2FCQ8
names: Similarity
messages: Belongs to the SOS response-associated peptidase family.

1871111:DJ533 RS02335
gene id: 1871111:DJ533_RS02335
uniprot id: A0A2S2F947
names: Similarity
messages: Belongs to the 4-hydroxy-2-oxovalerate aldolase family.

1871111:DJ533 RS08960
gene id: 1871111:DJ533_RS08960
uniprot id: A0A2S2FCI2
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit A family.

1871111:DJ533 RS16860
gene id: 1871111:DJ533_RS16860
uniprot id: A0A2S2FGM7
names: Subcellular Location Annotation
messages: Membrane