1863:CKV89 RS08890
gene id: 1863:CKV89_RS08890
uniprot id: A0A239VMT5
names: Similarity
messages: Belongs to the glutamine synthetase family.

1863:CKV89 RS05205
gene id: 1863:CKV89_RS05205
uniprot id: A0A239VEP2
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

1863:CKV89 RS05495
gene id: 1863:CKV89_RS05495
uniprot id: A0A239VF83
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

1863:CKV89 RS09740
gene id: 1863:CKV89_RS09740
uniprot id: A0A239VR56
names: Function
names: Similarity
messages: Belongs to the RmuC family.
messages: Involved in DNA recombination.

1863:CKV89 RS09985
gene id: 1863:CKV89_RS09985
uniprot id: A0A239VS13
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

1863:CKV89 RS05860
gene id: 1863:CKV89_RS05860
uniprot id: A0A239VHC9
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

1863:CKV89 RS02625
gene id: 1863:CKV89_RS02625
uniprot id: A0A239V9S9
names: Subcellular Location Annotation
messages: Membrane

1863:CKV89 RS06950
gene id: 1863:CKV89_RS06950
uniprot id: A0A239VJ95
names: Cofactor
messages: Binds 1 zinc ion per subunit.

1863:CKV89 RS01890
gene id: 1863:CKV89_RS01890
uniprot id: A0A239V7Y7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UreE family.
messages: Cytoplasm
messages: Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly.

1863:CKV89 RS09900
gene id: 1863:CKV89_RS09900
uniprot id: A0A239VRE0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

1863:CKV89 RS09950
gene id: 1863:CKV89_RS09950
uniprot id: A0A239VQ98
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

1863:CKV89 RS09320
gene id: 1863:CKV89_RS09320
uniprot id: A0A239VQ77
names: Similarity
messages: Belongs to the CobH/CbiC family.

1863:CKV89 RS05775
gene id: 1863:CKV89_RS05775
uniprot id: A0A239VHR8
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

1863:CKV89 RS06035
gene id: 1863:CKV89_RS06035
uniprot id: A0A239VGQ8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

1863:CKV89 RS05300
gene id: 1863:CKV89_RS05300
uniprot id: A0A239VFV4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

1863:CKV89 RS02225
gene id: 1863:CKV89_RS02225
uniprot id: A0A239V928
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein bS6.

1863:CKV89 RS05295
gene id: 1863:CKV89_RS05295
uniprot id: A0A239VGC9
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

1863:CKV89 RS09825
gene id: 1863:CKV89_RS09825
uniprot id: A0A239VPV5
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1863:CKV89 RS01080
gene id: 1863:CKV89_RS01080
uniprot id: A0A239V6H2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1863:CKV89 RS10600
gene id: 1863:CKV89_RS10600
uniprot id: A0A239VSB7
names: Similarity
messages: Belongs to the NAD synthetase family.

1863:CKV89 RS10290
gene id: 1863:CKV89_RS10290
uniprot id: A0A239VSM2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 30 kDa subunit family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1863:CKV89 RS03320
gene id: 1863:CKV89_RS03320
uniprot id: A0A239VC48
names: Function
names: Similarity
messages: Belongs to the uroporphyrinogen-III synthase family.
messages: Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.

1863:CKV89 RS08000
gene id: 1863:CKV89_RS08000
uniprot id: A0A239VM17
names: Similarity
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Homodimer.

1863:CKV89 RS04970
gene id: 1863:CKV89_RS04970
uniprot id: A0A239VEH2
names: Similarity
messages: Belongs to the phosphohexose mutase family.

1863:CKV89 RS08700
gene id: 1863:CKV89_RS08700
uniprot id: A0A239VNL6
names: Similarity
messages: Belongs to the acetyl-CoA hydrolase/transferase family.

1863:CKV89 RS03650
gene id: 1863:CKV89_RS03650
uniprot id: A0A239VDA4
names: Similarity
messages: Belongs to the peptidase A24 family.

1863:CKV89 RS09600
gene id: 1863:CKV89_RS09600
uniprot id: A0A239VPE6
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

1863:CKV89 RS04630
gene id: 1863:CKV89_RS04630
uniprot id: A0A239VDG3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

1863:CKV89 RS07440
gene id: 1863:CKV89_RS07440
uniprot id: A0A239VL47
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.
messages: In the N-terminal section; belongs to the CobB/CobQ family.
messages: Involved in acetate metabolism.
messages: The N-terminal region seems to be important for proper quaternary structure. The C-terminal region contains the substrate-binding site.

1863:CKV89 RS07915
gene id: 1863:CKV89_RS07915
uniprot id: A0A239VKZ4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Catalyzes the conjugation of the 1'-hydroxyl group of D-myo-inositol-3-phosphate (also named L-myo-inositol-1-phosphate) with a lipid tail of cytidine diphosphate diacylglycerol (CDP-DAG), forming phosphatidylinositol phosphate (PIP) and CMP. PIP is a precursor of phosphatidylinositol (PI) which is an essential lipid required for cell wall formation.
messages: Cell membrane
messages: Contains a di-nuclear catalytic Mg(2+) center.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1863:CKV89 RS10565
gene id: 1863:CKV89_RS10565
uniprot id: A0A239VSJ7
names: Similarity
messages: Belongs to the CsoR family.

1863:CKV89 RS04270
gene id: 1863:CKV89_RS04270
uniprot id: A0A239VD01
names: Function
names: Similarity
messages: Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.

1863:CKV89 RS07185
gene id: 1863:CKV89_RS07185
uniprot id: A0A239VJL1
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1863:CKV89 RS00315
gene id: 1863:CKV89_RS00315
uniprot id: A0A239V5K6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

1863:CKV89 RS05125
gene id: 1863:CKV89_RS05125
uniprot id: A0A239VG03
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FPG family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1863:CKV89 RS05175
gene id: 1863:CKV89_RS05175
uniprot id: A0A239VFW5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

1863:CKV89 RS09870
gene id: 1863:CKV89_RS09870
uniprot id: A0A239VRG0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

1863:CKV89 RS10025
gene id: 1863:CKV89_RS10025
uniprot id: A0A239VRP4
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1863:CKV89 RS04200
gene id: 1863:CKV89_RS04200
uniprot id: A0A239VDK0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

1863:CKV89 RS09885
gene id: 1863:CKV89_RS09885
uniprot id: A0A239VRC2
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

1863:CKV89 RS10760
gene id: 1863:CKV89_RS10760
uniprot id: A0A239VSS1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscL family.
messages: Cell membrane
messages: Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
messages: Homopentamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1863:CKV89 RS00040
gene id: 1863:CKV89_RS00040
uniprot id: A0A239V2H3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.

1863:CKV89 RS00850
gene id: 1863:CKV89_RS00850
uniprot id: A0A239V5V5
names: Subcellular Location Annotation
messages: Membrane

1863:CKV89 RS08925
gene id: 1863:CKV89_RS08925
uniprot id: A0A239VND8
names: Function
messages: Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.

1863:CKV89 RS12490
gene id: 1863:CKV89_RS12490
uniprot id: A0A239VCG6
names: Subcellular Location Annotation
messages: Membrane

1863:CKV89 RS05210
gene id: 1863:CKV89_RS05210
uniprot id: A0A239VFB2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: A probable RNA-binding protein.
messages: Belongs to the KhpA RNA-binding protein family.
messages: Cytoplasm

1863:CKV89 RS07580
gene id: 1863:CKV89_RS07580
uniprot id: A0A239VKA7
names: Subcellular Location Annotation
messages: Cytoplasm

1863:CKV89 RS05795
gene id: 1863:CKV89_RS05795
uniprot id: A0A239VGG1
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1863:CKV89 RS01465
gene id: 1863:CKV89_RS01465
uniprot id: A0A239V708
names: Subcellular Location Annotation
messages: Membrane

1863:CKV89 RS10170
gene id: 1863:CKV89_RS10170
uniprot id: A0A239VQY8
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

1863:CKV89 RS09920
gene id: 1863:CKV89_RS09920
uniprot id: A0A239VRW5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

1863:CKV89 RS04765
gene id: 1863:CKV89_RS04765
uniprot id: A0A239VE09
names: Similarity
messages: Belongs to the AB hydrolase superfamily. Lipase family.

1863:CKV89 RS02190
gene id: 1863:CKV89_RS02190
uniprot id: A0A9Q2UGI1
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1863:CKV89 RS03475
gene id: 1863:CKV89_RS03475
uniprot id: A0A239VBH9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
messages: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.
messages: Homodimer.

1863:CKV89 RS08620
gene id: 1863:CKV89_RS08620
uniprot id: A0A239VNA6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 2 subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

1863:CKV89 RS01870
gene id: 1863:CKV89_RS01870
uniprot id: A0A239V7G4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the urea transporter family.
messages: Cell membrane
messages: Membrane

1863:CKV89 RS01990
gene id: 1863:CKV89_RS01990
uniprot id: A0A239V7N9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1863:CKV89 RS01140
gene id: 1863:CKV89_RS01140
uniprot id: A0A239V878
names: Function
messages: Catalyzes the phosphorylation of hydroxymethylpyrimidine phosphate (HMP-P) to HMP-PP, and of HMP to HMP-P.

1863:CKV89 RS02355
gene id: 1863:CKV89_RS02355
uniprot id: A0A239V8W3
names: Similarity
messages: Belongs to the GMC oxidoreductase family.

1863:CKV89 RS07180
gene id: 1863:CKV89_RS07180
uniprot id: A0A239VKI7
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

1863:CKV89 RS08235
gene id: 1863:CKV89_RS08235
uniprot id: A0A239VN08
names: Similarity
messages: Belongs to the peptidase T1A family.

1863:CKV89 RS06525
gene id: 1863:CKV89_RS06525
uniprot id: A0A239VIP8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metallo-dependent hydrolases superfamily. HutI family.
messages: Binds 1 zinc or iron ion per subunit.
messages: Catalyzes the hydrolytic cleavage of the carbon-nitrogen bond in imidazolone-5-propanoate to yield N-formimidoyl-L-glutamate. It is the third step in the universal histidine degradation pathway.
messages: Cytoplasm

1863:CKV89 RS08655
gene id: 1863:CKV89_RS08655
uniprot id: A0A239VN48
names: Function
names: Similarity
messages: Belongs to the WhiA family.
messages: Involved in cell division and chromosome segregation.

1863:CKV89 RS06335
gene id: 1863:CKV89_RS06335
uniprot id: A0A239VIT7
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

1863:CKV89 RS00050
gene id: 1863:CKV89_RS00050
uniprot id: A0A239V2T6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MetA family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.

1863:CKV89 RS06955
gene id: 1863:CKV89_RS06955
uniprot id: A0A239VKE7
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family.

1863:CKV89 RS09940
gene id: 1863:CKV89_RS09940
uniprot id: A0A239VRX6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

1863:CKV89 RS07050
gene id: 1863:CKV89_RS07050
uniprot id: A0A239VKE4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

1863:CKV89 RS06520
gene id: 1863:CKV89_RS06520
uniprot id: A0A239VIU7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the urocanase family.
messages: Binds 1 NAD(+) per subunit.
messages: Catalyzes the conversion of urocanate to 4-imidazolone-5-propionate.
messages: Cytoplasm

1863:CKV89 RS09975
gene id: 1863:CKV89_RS09975
uniprot id: A0A239VS05
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

1863:CKV89 RS06585
gene id: 1863:CKV89_RS06585
uniprot id: A0A239VIZ1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase PH family.
messages: Homohexameric ring arranged as a trimer of dimers.
messages: Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.

1863:CKV89 RS09250
gene id: 1863:CKV89_RS09250
uniprot id: A0A239VNI3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associates with subunits I, II and III to form cytochrome c oxidase.
messages: Belongs to the cytochrome c oxidase bacterial subunit CtaF family.
messages: Cell membrane
messages: Membrane
messages: Part of cytochrome c oxidase, its function is unknown.

1863:CKV89 RS01730
gene id: 1863:CKV89_RS01730
uniprot id: A0A239V750
names: Similarity
names: Subunit
messages: Belongs to the glutaminase family.
messages: Homotetramer.

1863:CKV89 RS01580
gene id: 1863:CKV89_RS01580
uniprot id: A0A239V952
names: Function
messages: Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate.

1863:CKV89 RS07955
gene id: 1863:CKV89_RS07955
uniprot id: A0A239VM05
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvC family.
messages: Binds 2 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer which binds Holliday junction (HJ) DNA. The HJ becomes 2-fold symmetrical on binding to RuvC with unstacked arms; it has a different conformation from HJ DNA in complex with RuvA. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair. Endonuclease that resolves HJ intermediates. Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction. The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'. Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange. HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

1863:CKV89 RS10605
gene id: 1863:CKV89_RS10605
uniprot id: A0A9Q2YT91
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1863:CKV89 RS03510
gene id: 1863:CKV89_RS03510
uniprot id: A0A239VBI5
names: Similarity
messages: Belongs to the carotenoid/retinoid oxidoreductase family.

1863:CKV89 RS03430
gene id: 1863:CKV89_RS03430
uniprot id: A0A239VBY6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cell surface
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
messages: capsule
messages: cell wall

1863:CKV89 RS01845
gene id: 1863:CKV89_RS01845
uniprot id: A0A239V7G7
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1863:CKV89 RS05540
gene id: 1863:CKV89_RS05540
uniprot id: A0A239VHR5
names: Subcellular Location Annotation
messages: Membrane

1863:CKV89 RS02240
gene id: 1863:CKV89_RS02240
uniprot id: A0A239V8P3
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity.

1863:CKV89 RS09880
gene id: 1863:CKV89_RS09880
uniprot id: A0A239VQ40
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

1863:CKV89 RS05890
gene id: 1863:CKV89_RS05890
uniprot id: A0A239VGQ6
names: Similarity
messages: Belongs to the GMC oxidoreductase family.

1863:CKV89 RS10330
gene id: 1863:CKV89_RS10330
uniprot id: A0A239VRI8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

1863:CKV89 RS09690
gene id: 1863:CKV89_RS09690
uniprot id: A0A239VPG0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0126 family.
messages: Membrane

1863:CKV89 RS08885
gene id: 1863:CKV89_RS08885
uniprot id: A0A239VPC6
names: Subcellular Location Annotation
messages: Membrane

1863:CKV89 RS12085
gene id: 1863:CKV89_RS12085
uniprot id: A0A239VJE4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

1863:CKV89 RS05715
gene id: 1863:CKV89_RS05715
uniprot id: A0A239VHU0
names: Subcellular Location Annotation
messages: Membrane

1863:CKV89 RS08085
gene id: 1863:CKV89_RS08085
uniprot id: A0A239VMI2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

1863:CKV89 RS10675
gene id: 1863:CKV89_RS10675
uniprot id: A0A239VUE2
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.

1863:CKV89 RS01285
gene id: 1863:CKV89_RS01285
uniprot id: A0A239V6L0
names: Similarity
messages: Belongs to the Dps family.

1863:CKV89 RS07675
gene id: 1863:CKV89_RS07675
uniprot id: A0A239VLI9
names: Similarity
messages: Belongs to the thioesterase family.

1863:CKV89 RS02180
gene id: 1863:CKV89_RS02180
uniprot id: A0A239VA45
names: Subcellular Location Annotation
messages: Membrane

1863:CKV89 RS04155
gene id: 1863:CKV89_RS04155
uniprot id: A0A239VCN8
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1863:CKV89 RS07080
gene id: 1863:CKV89_RS07080
uniprot id: A0A239VKI9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methylthiotransferase family. RimO subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein uS12.
messages: Cytoplasm

1863:CKV89 RS03550
gene id: 1863:CKV89_RS03550
uniprot id: A0A239VBS6
names: Similarity
messages: Belongs to the IMPDH/GMPR family.

1863:CKV89 RS04720
gene id: 1863:CKV89_RS04720
uniprot id: A0A239VDV6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NucS endonuclease family.
messages: Cleaves both 3' and 5' ssDNA extremities of branched DNA structures.
messages: Cytoplasm

1863:CKV89 RS04700
gene id: 1863:CKV89_RS04700
uniprot id: A0A239VDP5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.

1863:CKV89 RS04465
gene id: 1863:CKV89_RS04465
uniprot id: A0A239VE88
names: Similarity
messages: Belongs to the helicase family. RAD25/XPB subfamily.

1863:CKV89 RS09815
gene id: 1863:CKV89_RS09815
uniprot id: A0A9Q2YTG3
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

1863:CKV89 RS00735
gene id: 1863:CKV89_RS00735
uniprot id: A0A239V4Q5
names: Subcellular Location Annotation
messages: Membrane

1863:CKV89 RS00895
gene id: 1863:CKV89_RS00895
uniprot id: A0A239V776
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NrfD family.
messages: Membrane

1863:CKV89 RS05500
gene id: 1863:CKV89_RS05500
uniprot id: A0A239VFT2
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

1863:CKV89 RS06330
gene id: 1863:CKV89_RS06330
uniprot id: A0A239VI96
names: Similarity
messages: Belongs to the PGI/PMI family.

1863:CKV89 RS05360
gene id: 1863:CKV89_RS05360
uniprot id: A0A239VEU8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

1863:CKV89 RS09665
gene id: 1863:CKV89_RS09665
uniprot id: A0A239VQW6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

1863:CKV89 RS02605
gene id: 1863:CKV89_RS02605
uniprot id: A0A239VAP0
names: Subcellular Location Annotation
messages: Membrane

1863:CKV89 RS00865
gene id: 1863:CKV89_RS00865
uniprot id: A0A239V549
names: Subcellular Location Annotation
messages: Membrane

1863:CKV89 RS11310
gene id: 1863:CKV89_RS11310
uniprot id: A0A239VVT4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

1863:CKV89 RS03200
gene id: 1863:CKV89_RS03200
uniprot id: A0A239VAS2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Cytoplasm
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
messages: The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.

1863:CKV89 RS10185
gene id: 1863:CKV89_RS10185
uniprot id: A0A239VSC0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

1863:CKV89 RS09980
gene id: 1863:CKV89_RS09980
uniprot id: A0A239VS21
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

1863:CKV89 RS04005
gene id: 1863:CKV89_RS04005
uniprot id: A0A239VD14
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family.

1863:CKV89 RS00995
gene id: 1863:CKV89_RS00995
uniprot id: A0A239V607
names: Function
names: Similarity
messages: Belongs to the catalase family. HPII subfamily.
messages: Serves to protect cells from the toxic effects of hydrogen peroxide.

1863:CKV89 RS08595
gene id: 1863:CKV89_RS08595
uniprot id: A0A239VLU4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1863:CKV89 RS04625
gene id: 1863:CKV89_RS04625
uniprot id: A0A239VDD6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

1863:CKV89 RS04635
gene id: 1863:CKV89_RS04635
uniprot id: A0A239VEY7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

1863:CKV89 RS02455
gene id: 1863:CKV89_RS02455
uniprot id: A0A9Q2UEM7
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1863:CKV89 RS04830
gene id: 1863:CKV89_RS04830
uniprot id: A0A239VE48
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

1863:CKV89 RS05010
gene id: 1863:CKV89_RS05010
uniprot id: A0A239VEM2
names: Subcellular Location Annotation
messages: Membrane

1863:CKV89 RS06110
gene id: 1863:CKV89_RS06110
uniprot id: A0A239VIU0
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1863:CKV89 RS06555
gene id: 1863:CKV89_RS06555
uniprot id: A0A239VIA3
names: Subcellular Location Annotation
messages: Membrane

1863:CKV89 RS04920
gene id: 1863:CKV89_RS04920
uniprot id: A0A239VE94
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

1863:CKV89 RS07140
gene id: 1863:CKV89_RS07140
uniprot id: A0A239VKA1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecX family.
messages: Cytoplasm
messages: Modulates RecA activity.

1863:CKV89 RS09845
gene id: 1863:CKV89_RS09845
uniprot id: A0A239VQH0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

1863:CKV89 RS01120
gene id: 1863:CKV89_RS01120
uniprot id: A0A239V5S0
names: Similarity
messages: Belongs to the glycosyl hydrolase 65 family.

1863:CKV89 RS06205
gene id: 1863:CKV89_RS06205
uniprot id: A0A239VI58
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nicotinamide ribonucleoside (NR) uptake permease (TC 4.B.1) family.
messages: Membrane

1863:CKV89 RS04815
gene id: 1863:CKV89_RS04815
uniprot id: A0A239VE10
names: Similarity
messages: Belongs to the peptidase M1 family.

1863:CKV89 RS04825
gene id: 1863:CKV89_RS04825
uniprot id: A0A239VE08
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.

1863:CKV89 RS05480
gene id: 1863:CKV89_RS05480
uniprot id: A0A239VGS0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

1863:CKV89 RS02230
gene id: 1863:CKV89_RS02230
uniprot id: A0A239VAH7
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

1863:CKV89 RS07335
gene id: 1863:CKV89_RS07335
uniprot id: A0A239VL74
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

1863:CKV89 RS03210
gene id: 1863:CKV89_RS03210
uniprot id: A0A239VAW8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1863:CKV89 RS03975
gene id: 1863:CKV89_RS03975
uniprot id: A0A239VD38
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

1863:CKV89 RS07225
gene id: 1863:CKV89_RS07225
uniprot id: A0A239VJD4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

1863:CKV89 RS09580
gene id: 1863:CKV89_RS09580
uniprot id: A0A9Q2YT45
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1863:CKV89 RS06860
gene id: 1863:CKV89_RS06860
uniprot id: A0A239VJF1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

1863:CKV89 RS01905
gene id: 1863:CKV89_RS01905
uniprot id: A0A239V814
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the urease gamma subunit family.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

1863:CKV89 RS03595
gene id: 1863:CKV89_RS03595
uniprot id: A0A239VC96
names: Subcellular Location Annotation
messages: Membrane

1863:CKV89 RS05250
gene id: 1863:CKV89_RS05250
uniprot id: A0A239VG33
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

1863:CKV89 RS07295
gene id: 1863:CKV89_RS07295
uniprot id: A0A239VKQ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit E family.
messages: Cell membrane
messages: Membrane

1863:CKV89 RS04835
gene id: 1863:CKV89_RS04835
uniprot id: A0A239VFM1
names: Activity Regulation
names: Caution
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Inhibited by fructose 1,6-bisphosphate (FBP).
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1863:CKV89 RS01880
gene id: 1863:CKV89_RS01880
uniprot id: A0A239V9P3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SIMIBI class G3E GTPase family. UreG subfamily.
messages: Cytoplasm
messages: Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG.
messages: Homodimer. UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

1863:CKV89 RS10180
gene id: 1863:CKV89_RS10180
uniprot id: A0A239VSM9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

1863:CKV89 RS03585
gene id: 1863:CKV89_RS03585
uniprot id: A0A239VD64
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MurCDEF family. MurT subfamily.
messages: Forms a heterodimer with GatD.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The lipid II isoglutaminyl synthase complex catalyzes the formation of alpha-D-isoglutamine in the cell wall lipid II stem peptide. The MurT subunit catalyzes the ATP-dependent amidation of D-glutamate residue of lipid II, converting it to an isoglutamine residue.

1863:CKV89 RS00420
gene id: 1863:CKV89_RS00420
uniprot id: A0A239V4N7
names: Cofactor
names: Similarity
messages: Belongs to the mannose-6-phosphate isomerase type 1 family.
messages: Binds 1 zinc ion per subunit.

1863:CKV89 RS04485
gene id: 1863:CKV89_RS04485
uniprot id: A0A239VD20
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Membrane

1863:CKV89 RS05635
gene id: 1863:CKV89_RS05635
uniprot id: A0A239VHM8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

1863:CKV89 RS10255
gene id: 1863:CKV89_RS10255
uniprot id: A0A239VR91
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 6 family.
messages: Cell membrane
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1863:CKV89 RS11150
gene id: 1863:CKV89_RS11150
uniprot id: A0A239VUC5
names: Similarity
messages: Belongs to the MotB family.

1863:CKV89 RS03090
gene id: 1863:CKV89_RS03090
uniprot id: A0A239VAH6
names: Subcellular Location Annotation
messages: Membrane

1863:CKV89 RS05380
gene id: 1863:CKV89_RS05380
uniprot id: A0A239VEY5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1863:CKV89 RS08675
gene id: 1863:CKV89_RS08675
uniprot id: A0A239VM07
names: Function
messages: Iron-sulfur subunit of the cytochrome bc1 complex, an essential component of the respiratory electron transport chain required for ATP synthesis. The bc1 complex catalyzes the oxidation of menaquinol and the reduction of cytochrome c in the respiratory chain. The bc1 complex operates through a Q-cycle mechanism that couples electron transfer to generation of the proton gradient that drives ATP synthesis.

1863:CKV89 RS01415
gene id: 1863:CKV89_RS01415
uniprot id: A0A239V8V1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Amino acid transporter (AAT) (TC 2.A.3.1) family.
messages: Membrane

1863:CKV89 RS07660
gene id: 1863:CKV89_RS07660
uniprot id: A0A239VLL0
names: Subcellular Location Annotation
messages: Membrane

1863:CKV89 RS04570
gene id: 1863:CKV89_RS04570
uniprot id: A0A239VDH6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

1863:CKV89 RS03190
gene id: 1863:CKV89_RS03190
uniprot id: A0A239VAH1
names: Similarity
messages: Belongs to the peptidase S13 family.

1863:CKV89 RS03185
gene id: 1863:CKV89_RS03185
uniprot id: A0A239VB56
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PPase family.
messages: Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
messages: Cytoplasm
messages: Homohexamer.

1863:CKV89 RS01290
gene id: 1863:CKV89_RS01290
uniprot id: A0A239V674
names: Similarity
messages: Belongs to the peptidase S8 family.

1863:CKV89 RS09765
gene id: 1863:CKV89_RS09765
uniprot id: A0A239VPQ5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

1863:CKV89 RS02560
gene id: 1863:CKV89_RS02560
uniprot id: A0A239V9C9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

1863:CKV89 RS04440
gene id: 1863:CKV89_RS04440
uniprot id: A0A239VEK2
names: Subcellular Location Annotation
messages: Membrane

1863:CKV89 RS09330
gene id: 1863:CKV89_RS09330
uniprot id: A0A239VQJ5
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

1863:CKV89 RS05765
gene id: 1863:CKV89_RS05765
uniprot id: A0A239VG57
names: Similarity
messages: Belongs to the class-II fumarase/aspartase family. Aspartase subfamily.

1863:CKV89 RS09935
gene id: 1863:CKV89_RS09935
uniprot id: A0A239VQT0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

1863:CKV89 RS05670
gene id: 1863:CKV89_RS05670
uniprot id: A0A239VHY6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

1863:CKV89 RS10250
gene id: 1863:CKV89_RS10250
uniprot id: A0A239VR93
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1863:CKV89 RS01470
gene id: 1863:CKV89_RS01470
uniprot id: A0A239V6K7
names: Activity Regulation
names: Caution
names: Function
names: Similarity
messages: Allosterically activated by N-acetylglucosamine 6-phosphate (GlcNAc6P).
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily.
messages: Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1863:CKV89 RS10225
gene id: 1863:CKV89_RS10225
uniprot id: A0A9Q2UEV2
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1863:CKV89 RS01340
gene id: 1863:CKV89_RS01340
uniprot id: A0A9Q2YRT2
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1863:CKV89 RS11155
gene id: 1863:CKV89_RS11155
uniprot id: A0A239VU23
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MotA family.
messages: Membrane

1863:CKV89 RS04775
gene id: 1863:CKV89_RS04775
uniprot id: A0A239VDY0
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family. TreS subfamily.

1863:CKV89 RS06895
gene id: 1863:CKV89_RS06895
uniprot id: A0A239VJG6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

1863:CKV89 RS06145
gene id: 1863:CKV89_RS06145
uniprot id: A0A239VIG2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1863:CKV89 RS04100
gene id: 1863:CKV89_RS04100
uniprot id: A0A239VCK6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IA subfamily.
messages: Cell membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system and for the release of the potassium ions to the cytoplasm.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

1863:CKV89 RS07105
gene id: 1863:CKV89_RS07105
uniprot id: A0A239VL05
names: Similarity
messages: Belongs to the FPG family.

1863:CKV89 RS03940
gene id: 1863:CKV89_RS03940
uniprot id: A0A239VCC0
names: Similarity
messages: In the N-terminal section; belongs to the cytochrome P450 family.

1863:CKV89 RS11485
gene id: 1863:CKV89_RS11485
uniprot id: A0A239VVD9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LemA family.
messages: Membrane

1863:CKV89 RS08295
gene id: 1863:CKV89_RS08295
uniprot id: A0A239VMJ4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. Biotin synthase family.
messages: Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
messages: Homodimer.

1863:CKV89 RS08760
gene id: 1863:CKV89_RS08760
uniprot id: A0A239VM81
names: Similarity
messages: Belongs to the glutamate synthase family.

1863:CKV89 RS05155
gene id: 1863:CKV89_RS05155
uniprot id: A0A239VF46
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.

1863:CKV89 RS05005
gene id: 1863:CKV89_RS05005
uniprot id: A0A239VEF8
names: Function
messages: Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.

1863:CKV89 RS04840
gene id: 1863:CKV89_RS04840
uniprot id: A0A239VF28
names: Subcellular Location Annotation
messages: Membrane

1863:CKV89 RS08460
gene id: 1863:CKV89_RS08460
uniprot id: A0A239VN80
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. MoaA family.
messages: Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.
messages: Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
messages: Monomer and homodimer.

1863:CKV89 RS02610
gene id: 1863:CKV89_RS02610
uniprot id: A0A239VB25
names: Subcellular Location Annotation
messages: Membrane

1863:CKV89 RS04940
gene id: 1863:CKV89_RS04940
uniprot id: A0A239VFL6
names: Subcellular Location Annotation
messages: Membrane

1863:CKV89 RS10860
gene id: 1863:CKV89_RS10860
uniprot id: A0A239VU75
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

1863:CKV89 RS08110
gene id: 1863:CKV89_RS08110
uniprot id: A0A239VKR2
names: Similarity
messages: Belongs to the heat shock protein 70 family.

1863:CKV89 RS07420
gene id: 1863:CKV89_RS07420
uniprot id: A0A239VL37
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

1863:CKV89 RS07365
gene id: 1863:CKV89_RS07365
uniprot id: A0A239VJG5
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

1863:CKV89 RS08865
gene id: 1863:CKV89_RS08865
uniprot id: A0A239VMR4
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

1863:CKV89 RS11040
gene id: 1863:CKV89_RS11040
uniprot id: A0A239VTZ6
names: Subcellular Location Annotation
messages: Membrane

1863:CKV89 RS07325
gene id: 1863:CKV89_RS07325
uniprot id: A0A239VLB9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoD/SigA subfamily.
messages: Cytoplasm
messages: Interacts transiently with the RNA polymerase catalytic core.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.

1863:CKV89 RS09960
gene id: 1863:CKV89_RS09960
uniprot id: A0A239VRP8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

1863:CKV89 RS00570
gene id: 1863:CKV89_RS00570
uniprot id: A0A239V439
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.

1863:CKV89 RS02785
gene id: 1863:CKV89_RS02785
uniprot id: A0A239V9U7
names: Similarity
messages: Belongs to the peptidase S13 family.

1863:CKV89 RS04610
gene id: 1863:CKV89_RS04610
uniprot id: A0A239VDK6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Membrane

1863:CKV89 RS06095
gene id: 1863:CKV89_RS06095
uniprot id: A0A239VHZ2
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

1863:CKV89 RS05610
gene id: 1863:CKV89_RS05610
uniprot id: A0A239VHD8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MraZ family.
messages: Forms oligomers.
messages: nucleoid

1863:CKV89 RS02165
gene id: 1863:CKV89_RS02165
uniprot id: A0A239VAC1
names: Similarity
messages: Belongs to the thioredoxin family.

1863:CKV89 RS04575
gene id: 1863:CKV89_RS04575
uniprot id: A0A239VF54
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

1863:CKV89 RS05415
gene id: 1863:CKV89_RS05415
uniprot id: A0A239VF10
names: Similarity
messages: Belongs to the carbamate kinase family.

1863:CKV89 RS08650
gene id: 1863:CKV89_RS08650
uniprot id: A0A239VNQ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
messages: Cytoplasm

1863:CKV89 RS09575
gene id: 1863:CKV89_RS09575
uniprot id: A0A239VQK2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.

1863:CKV89 RS10205
gene id: 1863:CKV89_RS10205
uniprot id: A0A9Q2UCX1
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1863:CKV89 RS08635
gene id: 1863:CKV89_RS08635
uniprot id: A0A239VLX5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Membrane

1863:CKV89 RS10300
gene id: 1863:CKV89_RS10300
uniprot id: A0A239VT10
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 3 family.
messages: Cell membrane
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.

1863:CKV89 RS01505
gene id: 1863:CKV89_RS01505
uniprot id: A0A239V6P7
names: Subcellular Location Annotation
messages: Membrane

1863:CKV89 RS06005
gene id: 1863:CKV89_RS06005
uniprot id: A0A239VHT9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transglycosylase MltG family.
messages: Cell membrane
messages: Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.

1863:CKV89 RS05425
gene id: 1863:CKV89_RS05425
uniprot id: A0A239VF21
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arginine deiminase family.
messages: Cytoplasm

1863:CKV89 RS10175
gene id: 1863:CKV89_RS10175
uniprot id: A0A239VR20
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

1863:CKV89 RS04550
gene id: 1863:CKV89_RS04550
uniprot id: A0A239VDD9
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

1863:CKV89 RS00985
gene id: 1863:CKV89_RS00985
uniprot id: A0A239V5F4
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1863:CKV89 RS04975
gene id: 1863:CKV89_RS04975
uniprot id: A0A239VFZ0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1863:CKV89 RS07390
gene id: 1863:CKV89_RS07390
uniprot id: A0A239VJM7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

1863:CKV89 RS08870
gene id: 1863:CKV89_RS08870
uniprot id: A0A239VMK3
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LipB family.
messages: Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
messages: Cytoplasm
messages: In the reaction, the free carboxyl group of octanoic acid is attached via an amide linkage to the epsilon-amino group of a specific lysine residue of lipoyl domains of lipoate-dependent enzymes.

1863:CKV89 RS08940
gene id: 1863:CKV89_RS08940
uniprot id: A0A239VPM4
names: Function
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.
messages: Catalyzes the isomerization of citrate to isocitrate via cis-aconitate.

1863:CKV89 RS10020
gene id: 1863:CKV89_RS10020
uniprot id: A0A239VQG2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

1863:CKV89 RS06805
gene id: 1863:CKV89_RS06805
uniprot id: A0A239VK31
names: Similarity
messages: Belongs to the peptidase M1 family.

1863:CKV89 RS01600
gene id: 1863:CKV89_RS01600
uniprot id: A0A239V7A1
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane
messages: Membrane

1863:CKV89 RS10640
gene id: 1863:CKV89_RS10640
uniprot id: A0A239VTW5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

1863:CKV89 RS03555
gene id: 1863:CKV89_RS03555
uniprot id: A0A239VDK3
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SURF1 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1863:CKV89 RS00260
gene id: 1863:CKV89_RS00260
uniprot id: A0A239V3T3
names: Similarity
messages: Belongs to the glycosyl hydrolase 26 family.

1863:CKV89 RS02215
gene id: 1863:CKV89_RS02215
uniprot id: A0A239V8C9
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with bS18 to 16S ribosomal RNA.

1863:CKV89 RS07120
gene id: 1863:CKV89_RS07120
uniprot id: A0A239VJ74
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1863:CKV89 RS00320
gene id: 1863:CKV89_RS00320
uniprot id: A0A239V4D2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

1863:CKV89 RS02810
gene id: 1863:CKV89_RS02810
uniprot id: A0A239VB60
names: Subcellular Location Annotation
messages: Cytoplasm

1863:CKV89 RS10740
gene id: 1863:CKV89_RS10740
uniprot id: A0A239VUA8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MoaC family.
messages: Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
messages: Homohexamer; trimer of dimers.

1863:CKV89 RS01380
gene id: 1863:CKV89_RS01380
uniprot id: A0A239V8T2
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

1863:CKV89 RS10230
gene id: 1863:CKV89_RS10230
uniprot id: A0A239VSU2
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

1863:CKV89 RS06710
gene id: 1863:CKV89_RS06710
uniprot id: A0A239VJ47
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.
messages: Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).
messages: The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.
messages: The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1.

1863:CKV89 RS09930
gene id: 1863:CKV89_RS09930
uniprot id: A0A239VRY9
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

1863:CKV89 RS09830
gene id: 1863:CKV89_RS09830
uniprot id: A0A239VRB8
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

1863:CKV89 RS00410
gene id: 1863:CKV89_RS00410
uniprot id: A0A239V591
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1863:CKV89 RS10295
gene id: 1863:CKV89_RS10295
uniprot id: A0A9Q2UET5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 20 kDa subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1863:CKV89 RS05690
gene id: 1863:CKV89_RS05690
uniprot id: A0A239VHK0
names: Similarity
messages: Belongs to the YggT family.

1863:CKV89 RS09715
gene id: 1863:CKV89_RS09715
uniprot id: A0A239VRI1
names: Similarity
messages: Belongs to the helicase family. RecQ subfamily.

1863:CKV89 RS10035
gene id: 1863:CKV89_RS10035
uniprot id: A0A239VSE9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.

1863:CKV89 RS01895
gene id: 1863:CKV89_RS01895
uniprot id: A0A239V907
names: Cofactor
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family.
messages: Binds 2 nickel ions per subunit.
messages: Carbamylation allows a single lysine to coordinate two nickel ions.
messages: Carboxylation allows a single lysine to coordinate two nickel ions.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

1863:CKV89 RS09710
gene id: 1863:CKV89_RS09710
uniprot id: A0A239VQW2
names: Subcellular Location Annotation
messages: Membrane

1863:CKV89 RS09540
gene id: 1863:CKV89_RS09540
uniprot id: A0A239VQD5
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

1863:CKV89 RS05335
gene id: 1863:CKV89_RS05335
uniprot id: A0A239VF51
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lactate permease family.
messages: Cell membrane
messages: Membrane
messages: Uptake of L-lactate across the membrane. Can also transport D-lactate and glycolate.

1863:CKV89 RS08830
gene id: 1863:CKV89_RS08830
uniprot id: A0A239VNL8
names: Function
names: Similarity
messages: Belongs to the CobU/CobP family.
messages: Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate.

1863:CKV89 RS05445
gene id: 1863:CKV89_RS05445
uniprot id: A0A239VGV1
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the peroxiredoxin family. Tpx subfamily.
messages: Homodimer.
messages: The active site is a conserved redox-active cysteine residue, the peroxidatic cysteine (C(P)), which makes the nucleophilic attack on the peroxide substrate. The peroxide oxidizes the C(P)-SH to cysteine sulfenic acid (C(P)-SOH), which then reacts with another cysteine residue, the resolving cysteine (C(R)), to form a disulfide bridge. The disulfide is subsequently reduced by an appropriate electron donor to complete the catalytic cycle. In this atypical 2-Cys peroxiredoxin, C(R) is present in the same subunit to form an intramolecular disulfide. The disulfide is subsequently reduced by thioredoxin.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

1863:CKV89 RS07515
gene id: 1863:CKV89_RS07515
uniprot id: A0A239VLL7
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

1863:CKV89 RS09040
gene id: 1863:CKV89_RS09040
uniprot id: A0A239VPY7
names: Similarity
messages: Belongs to the peptidase C40 family.

1863:CKV89 RS06380
gene id: 1863:CKV89_RS06380
uniprot id: A0A239VHY3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

1863:CKV89 RS08780
gene id: 1863:CKV89_RS08780
uniprot id: A0A239VMB1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

1863:CKV89 RS06830
gene id: 1863:CKV89_RS06830
uniprot id: A0A239VJL9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

1863:CKV89 RS02170
gene id: 1863:CKV89_RS02170
uniprot id: A0A239V9J2
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

1863:CKV89 RS08525
gene id: 1863:CKV89_RS08525
uniprot id: A0A239VMU4
names: Subcellular Location Annotation
messages: Membrane

1863:CKV89 RS05705
gene id: 1863:CKV89_RS05705
uniprot id: A0A239VG23
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

1863:CKV89 RS03370
gene id: 1863:CKV89_RS03370
uniprot id: A0A239VB72
names: Subcellular Location Annotation
messages: Membrane

1863:CKV89 RS08640
gene id: 1863:CKV89_RS08640
uniprot id: A0A239VNV3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

1863:CKV89 RS10000
gene id: 1863:CKV89_RS10000
uniprot id: A0A239VQD8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1863:CKV89 RS03840
gene id: 1863:CKV89_RS03840
uniprot id: A0A239VDJ6
names: Subcellular Location Annotation
messages: Membrane

1863:CKV89 RS05800
gene id: 1863:CKV89_RS05800
uniprot id: A0A239VHT8
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1863:CKV89 RS10715
gene id: 1863:CKV89_RS10715
uniprot id: A0A239VU43
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Belongs to the precorrin methyltransferase family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

1863:CKV89 RS10635
gene id: 1863:CKV89_RS10635
uniprot id: A0A239VUA2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

1863:CKV89 RS02060
gene id: 1863:CKV89_RS02060
uniprot id: A0A239V8A9
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

1863:CKV89 RS10365
gene id: 1863:CKV89_RS10365
uniprot id: A0A239VRL6
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

1863:CKV89 RS01865
gene id: 1863:CKV89_RS01865
uniprot id: A0A239V7W1
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

1863:CKV89 RS06050
gene id: 1863:CKV89_RS06050
uniprot id: A0A239VHP9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetokinase family.
messages: Cytoplasm

1863:CKV89 RS08270
gene id: 1863:CKV89_RS08270
uniprot id: A0A239VMH5
names: Similarity
names: Subunit
messages: Belongs to the AAA ATPase family.
messages: Homohexamer. Assembles into a hexameric ring structure.

1863:CKV89 RS07215
gene id: 1863:CKV89_RS07215
uniprot id: A0A239VKN5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S24 family.
messages: Homodimer.
messages: Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.

1863:CKV89 RS04340
gene id: 1863:CKV89_RS04340
uniprot id: A0A239VD55
names: Function
names: Similarity
messages: Belongs to the trehalose phosphatase family.
messages: Removes the phosphate from trehalose 6-phosphate to produce free trehalose.

1863:CKV89 RS03325
gene id: 1863:CKV89_RS03325
uniprot id: A0A239VB00
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Homooctamer.

1863:CKV89 RS01585
gene id: 1863:CKV89_RS01585
uniprot id: A0A239V8B9
names: Subcellular Location Annotation
messages: Membrane

1863:CKV89 RS10135
gene id: 1863:CKV89_RS10135
uniprot id: A0A239VSP0
names: Subcellular Location Annotation
messages: Membrane

1863:CKV89 RS00880
gene id: 1863:CKV89_RS00880
uniprot id: A0A239V559
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the selenophosphate synthase 1 family. Class I subfamily.
messages: Binds 1 Mg(2+) ion per monomer.
messages: Homodimer.
messages: Synthesizes selenophosphate from selenide and ATP.

1863:CKV89 RS09590
gene id: 1863:CKV89_RS09590
uniprot id: A0A9Q2YRB2
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1863:CKV89 RS10405
gene id: 1863:CKV89_RS10405
uniprot id: A0A239VSZ3
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

1863:CKV89 RS08580
gene id: 1863:CKV89_RS08580
uniprot id: A0A239VNS0
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

1863:CKV89 RS01915
gene id: 1863:CKV89_RS01915
uniprot id: A0A239V7Q0
names: Similarity
messages: Belongs to the FPG family.

1863:CKV89 RS03300
gene id: 1863:CKV89_RS03300
uniprot id: A0A9Q2YQ84
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1863:CKV89 RS00805
gene id: 1863:CKV89_RS00805
uniprot id: A0A239V5R2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.

1863:CKV89 RS10690
gene id: 1863:CKV89_RS10690
uniprot id: A0A239VU11
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1863:CKV89 RS03025
gene id: 1863:CKV89_RS03025
uniprot id: A0A239VAU1
names: Function
names: Similarity
messages: Belongs to the glutaredoxin family.
messages: Electron transport system for the ribonucleotide reductase system NrdEF.

1863:CKV89 RS05355
gene id: 1863:CKV89_RS05355
uniprot id: A0A239VF69
names: Caution
names: Function
names: Similarity
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1863:CKV89 RS00395
gene id: 1863:CKV89_RS00395
uniprot id: A0A239V5T5
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

1863:CKV89 RS03640
gene id: 1863:CKV89_RS03640
uniprot id: A0A239VD53
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

1863:CKV89 RS03350
gene id: 1863:CKV89_RS03350
uniprot id: A0A239VB62
names: Subcellular Location Annotation
messages: Membrane

1863:CKV89 RS09670
gene id: 1863:CKV89_RS09670
uniprot id: A0A239VRD0
names: Similarity
messages: Belongs to the Nudix hydrolase family.

1863:CKV89 RS02235
gene id: 1863:CKV89_RS02235
uniprot id: A0A239V9M7
names: Subcellular Location Annotation
messages: Membrane

1863:CKV89 RS07400
gene id: 1863:CKV89_RS07400
uniprot id: A0A239VJI7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer.

1863:CKV89 RS05555
gene id: 1863:CKV89_RS05555
uniprot id: A0A239VGF8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

1863:CKV89 RS09255
gene id: 1863:CKV89_RS09255
uniprot id: A0A239VNJ4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Cell membrane
messages: Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.
messages: Membrane

1863:CKV89 RS00730
gene id: 1863:CKV89_RS00730
uniprot id: A0A239V5J0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

1863:CKV89 RS08100
gene id: 1863:CKV89_RS08100
uniprot id: A0A9Q2YSW5
names: Caution
names: Similarity
messages: Belongs to the N-acetylmuramoyl-L-alanine amidase 2 family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1863:CKV89 RS11220
gene id: 1863:CKV89_RS11220
uniprot id: A0A239VVM5
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliE family.

1863:CKV89 RS03035
gene id: 1863:CKV89_RS03035
uniprot id: A0A239VAC0
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

1863:CKV89 RS09325
gene id: 1863:CKV89_RS09325
uniprot id: A0A239VQM6
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

1863:CKV89 RS02285
gene id: 1863:CKV89_RS02285
uniprot id: A0A239V964
names: Subcellular Location Annotation
messages: Membrane

1863:CKV89 RS09910
gene id: 1863:CKV89_RS09910
uniprot id: A0A239VRK0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

1863:CKV89 RS06845
gene id: 1863:CKV89_RS06845
uniprot id: A0A239VK52
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

1863:CKV89 RS08625
gene id: 1863:CKV89_RS08625
uniprot id: A0A239VNN2
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1863:CKV89 RS08095
gene id: 1863:CKV89_RS08095
uniprot id: A0A239VLD7
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphofructokinase type A (PFKA) family. PPi-dependent PFK group II subfamily. Clade 'P' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions.
messages: Cytoplasm
messages: Homodimer or homotetramer.
messages: Non-allosteric.

1863:CKV89 RS05105
gene id: 1863:CKV89_RS05105
uniprot id: A0A239VFQ3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

1863:CKV89 RS07595
gene id: 1863:CKV89_RS07595
uniprot id: A0A239VJT3
names: Function
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.
messages: Catalyzes the ATP-dependent phosphorylation of fructose-l-phosphate to fructose-l,6-bisphosphate.

1863:CKV89 RS09850
gene id: 1863:CKV89_RS09850
uniprot id: A0A239VR85
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

1863:CKV89 RS10460
gene id: 1863:CKV89_RS10460
uniprot id: A0A239VTS3
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

1863:CKV89 RS07540
gene id: 1863:CKV89_RS07540
uniprot id: A0A239VLH2
names: Function
messages: Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).

1863:CKV89 RS04990
gene id: 1863:CKV89_RS04990
uniprot id: A0A239VG01
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

1863:CKV89 RS05420
gene id: 1863:CKV89_RS05420
uniprot id: A0A239VFE5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm

1863:CKV89 RS08445
gene id: 1863:CKV89_RS08445
uniprot id: A0A239VNE1
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.

1863:CKV89 RS05560
gene id: 1863:CKV89_RS05560
uniprot id: A0A239VG07
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

1863:CKV89 RS05995
gene id: 1863:CKV89_RS05995
uniprot id: A0A239VGN6
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

1863:CKV89 RS07765
gene id: 1863:CKV89_RS07765
uniprot id: A0A239VK43
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

1863:CKV89 RS03315
gene id: 1863:CKV89_RS03315
uniprot id: A0A239VAY8
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HMBS family.
messages: Binds 1 dipyrromethane group covalently.
messages: Monomer.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
messages: The porphobilinogen subunits are added to the dipyrromethane group.

1863:CKV89 RS00215
gene id: 1863:CKV89_RS00215
uniprot id: A0A239V309
names: Similarity
messages: Belongs to the UPF0246 family.

1863:CKV89 RS04760
gene id: 1863:CKV89_RS04760
uniprot id: A0A239VEN4
names: Similarity
messages: Belongs to the phosphohexose mutase family.

1863:CKV89 RS07340
gene id: 1863:CKV89_RS07340
uniprot id: A0A239VJM0
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1863:CKV89 RS05855
gene id: 1863:CKV89_RS05855
uniprot id: A0A239VGS4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1863:CKV89 RS08565
gene id: 1863:CKV89_RS08565
uniprot id: A0A239VM09
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

1863:CKV89 RS04415
gene id: 1863:CKV89_RS04415
uniprot id: A0A239VEH1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
messages: Cytoplasm
messages: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.

1863:CKV89 RS10095
gene id: 1863:CKV89_RS10095
uniprot id: A0A239VQP5
names: Function
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

1863:CKV89 RS07945
gene id: 1863:CKV89_RS07945
uniprot id: A0A239VLI5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glutaminase PdxT/SNO family.
messages: Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS.
messages: In the presence of PdxS, forms a dodecamer of heterodimers. Only shows activity in the heterodimer.

1863:CKV89 RS07615
gene id: 1863:CKV89_RS07615
uniprot id: A0A239VJX6
names: Subcellular Location Annotation
messages: Membrane

1863:CKV89 RS08710
gene id: 1863:CKV89_RS08710
uniprot id: A0A239VN89
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the UPF0157 (GrpB) family.
messages: In the N-terminal section; belongs to the CoaE family.

1863:CKV89 RS02025
gene id: 1863:CKV89_RS02025
uniprot id: A0A239V7X8
names: Subcellular Location Annotation
messages: Membrane

1863:CKV89 RS07520
gene id: 1863:CKV89_RS07520
uniprot id: A0A239VJP3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

1863:CKV89 RS06100
gene id: 1863:CKV89_RS06100
uniprot id: A0A239VID7
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1863:CKV89 RS04470
gene id: 1863:CKV89_RS04470
uniprot id: A0A239VD69
names: Similarity
messages: Belongs to the peptidase M13 family.

1863:CKV89 RS00755
gene id: 1863:CKV89_RS00755
uniprot id: A0A239V684
names: Function
messages: Catalyzes two reactions in de novo purine nucleotide biosynthesis. Catalyzes the breakdown of 5-aminoimidazole- (N-succinylocarboxamide) ribotide (SAICAR or 2-[5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamido]succinate) to 5-aminoimidazole-4-carboxamide ribotide (AICAR or 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide) and fumarate, and of adenylosuccinate (ADS or N(6)-(1,2-dicarboxyethyl)-AMP) to adenosine monophosphate (AMP) and fumarate.

1863:CKV89 RS03205
gene id: 1863:CKV89_RS03205
uniprot id: A0A239VB77
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm

1863:CKV89 RS07705
gene id: 1863:CKV89_RS07705
uniprot id: A0A239VLV1
names: Subcellular Location Annotation
messages: Membrane

1863:CKV89 RS00830
gene id: 1863:CKV89_RS00830
uniprot id: A0A239V6F0
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1863:CKV89 RS04275
gene id: 1863:CKV89_RS04275
uniprot id: A0A239VCZ5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

1863:CKV89 RS09970
gene id: 1863:CKV89_RS09970
uniprot id: A0A239VRN0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

1863:CKV89 RS03460
gene id: 1863:CKV89_RS03460
uniprot id: A0A239VDF5
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

1863:CKV89 RS09505
gene id: 1863:CKV89_RS09505
uniprot id: A0A239VQW5
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

1863:CKV89 RS12510
gene id: 1863:CKV89_RS12510
uniprot id: A0A239VDS9
names: Similarity
messages: Belongs to the transglycosylase family. Rpf subfamily.

1863:CKV89 RS08645
gene id: 1863:CKV89_RS08645
uniprot id: A0A239VNX2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Monomer.

1863:CKV89 RS07060
gene id: 1863:CKV89_RS07060
uniprot id: A0A239VJ48
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily.
messages: Cytoplasm
messages: Homodimer, may be a subunit of the RNA degradosome.

1863:CKV89 RS08185
gene id: 1863:CKV89_RS08185
uniprot id: A0A239VM24
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase-binding protein RbpA family.
messages: Bind 1 Zn(2+) per subunit.
messages: Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters.
messages: Forms a complex with the RNAP catalytic core and with free principal sigma factors.

1863:CKV89 RS12420
gene id: 1863:CKV89_RS12420
uniprot id: A0A239V5D5
names: Similarity
messages: Belongs to the CbxX/CfxQ family.

1863:CKV89 RS07370
gene id: 1863:CKV89_RS07370
uniprot id: A0A239VL07
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

1863:CKV89 RS09380
gene id: 1863:CKV89_RS09380
uniprot id: A0A239VQ59
names: Function
names: Similarity
messages: Belongs to the threonine synthase family.
messages: Catalyzes the gamma-elimination of phosphate from L-phosphohomoserine and the beta-addition of water to produce L-threonine.

1863:CKV89 RS09890
gene id: 1863:CKV89_RS09890
uniprot id: A0A239VRR3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

1863:CKV89 RS06155
gene id: 1863:CKV89_RS06155
uniprot id: A0A239VIG5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

1863:CKV89 RS05215
gene id: 1863:CKV89_RS05215
uniprot id: A0A239VEK4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein uS19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein uS19.

1863:CKV89 RS08840
gene id: 1863:CKV89_RS08840
uniprot id: A0A239VMH7
names: Similarity
messages: Belongs to the GcvT family.

1863:CKV89 RS11215
gene id: 1863:CKV89_RS11215
uniprot id: A0A239VU45
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliF family.
messages: Membrane
messages: The M ring may be actively involved in energy transduction.

1863:CKV89 RS07445
gene id: 1863:CKV89_RS07445
uniprot id: A0A239VKQ8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Mg(2+). Can also accept Mn(2+).

1863:CKV89 RS06065
gene id: 1863:CKV89_RS06065
uniprot id: A0A239VII9
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

1863:CKV89 RS06140
gene id: 1863:CKV89_RS06140
uniprot id: A0A239VGW8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

1863:CKV89 RS04590
gene id: 1863:CKV89_RS04590
uniprot id: A0A239VDI8
names: Subcellular Location Annotation
messages: Membrane

1863:CKV89 RS01150
gene id: 1863:CKV89_RS01150
uniprot id: A0A239V5P4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1863:CKV89 RS09860
gene id: 1863:CKV89_RS09860
uniprot id: A0A239VQ02
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

1863:CKV89 RS07610
gene id: 1863:CKV89_RS07610
uniprot id: A0A239VLA3
names: Subcellular Location Annotation
messages: Membrane

1863:CKV89 RS00090
gene id: 1863:CKV89_RS00090
uniprot id: A0A239V3J1
names: Function
messages: Electron transfer subunit of the terminal reductase during anaerobic growth on various sulfoxide and N-oxide compounds.

1863:CKV89 RS07345
gene id: 1863:CKV89_RS07345
uniprot id: A0A239VKX1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

1863:CKV89 RS08410
gene id: 1863:CKV89_RS08410
uniprot id: A0A239VND7
names: Similarity
messages: Belongs to the band 7/mec-2 family.

1863:CKV89 RS01910
gene id: 1863:CKV89_RS01910
uniprot id: A0A239V7M7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell membrane
messages: Membrane

1863:CKV89 RS09805
gene id: 1863:CKV89_RS09805
uniprot id: A0A239VRM1
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

1863:CKV89 RS05850
gene id: 1863:CKV89_RS05850
uniprot id: A0A239VHY5
names: Similarity
messages: Belongs to the TlyA family.

1863:CKV89 RS08025
gene id: 1863:CKV89_RS08025
uniprot id: A0A239VL81
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

1863:CKV89 RS04345
gene id: 1863:CKV89_RS04345
uniprot id: A0A239VD43
names: Similarity
messages: Belongs to the glycosyltransferase 20 family.

1863:CKV89 RS01475
gene id: 1863:CKV89_RS01475
uniprot id: A0A239V812
names: Cofactor
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. NagA family.
messages: Binds 1 divalent metal cation per subunit.

1863:CKV89 RS02120
gene id: 1863:CKV89_RS02120
uniprot id: A0A239V841
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

1863:CKV89 RS07265
gene id: 1863:CKV89_RS07265
uniprot id: A0A239VJA3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1863:CKV89 RS08475
gene id: 1863:CKV89_RS08475
uniprot id: A0A239VMP7
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.
messages: There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors.

1863:CKV89 RS09945
gene id: 1863:CKV89_RS09945
uniprot id: A0A239VQB3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

1863:CKV89 RS12410
gene id: 1863:CKV89_RS12410
uniprot id: A0A239V392
names: Subcellular Location Annotation
messages: Membrane

1863:CKV89 RS09025
gene id: 1863:CKV89_RS09025
uniprot id: A0A239VNN5
names: Similarity
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.

1863:CKV89 RS11240
gene id: 1863:CKV89_RS11240
uniprot id: A0A239VVS8
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CheB family.
messages: Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.
messages: Cytoplasm
messages: Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
messages: Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity.

1863:CKV89 RS07150
gene id: 1863:CKV89_RS07150
uniprot id: A0A239VJJ4
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1863:CKV89 RS04250
gene id: 1863:CKV89_RS04250
uniprot id: A0A239VDH8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

1863:CKV89 RS07795
gene id: 1863:CKV89_RS07795
uniprot id: A0A239VKC3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ChdC family. Type 2 subfamily.
messages: Fe-coproporphyrin III acts as both substrate and redox cofactor.
messages: Involved in coproporphyrin-dependent heme b biosynthesis. Catalyzes the decarboxylation of Fe-coproporphyrin III (coproheme) to heme b (protoheme IX), the last step of the pathway. The reaction occurs in a stepwise manner with a three-propionate intermediate.

1863:CKV89 RS02015
gene id: 1863:CKV89_RS02015
uniprot id: A0A9Q2UEH6
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1863:CKV89 RS08505
gene id: 1863:CKV89_RS08505
uniprot id: A0A239VMB2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) per subunit.
messages: Decarboxylates branched-chain and aromatic alpha-keto acids to aldehydes.

1863:CKV89 RS02820
gene id: 1863:CKV89_RS02820
uniprot id: A0A239VBZ5
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

1863:CKV89 RS01835
gene id: 1863:CKV89_RS01835
uniprot id: A0A239V998
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.
messages: Belongs to the organic radical-activating enzymes family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm

1863:CKV89 RS05375
gene id: 1863:CKV89_RS05375
uniprot id: A0A239VFA7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

1863:CKV89 RS11165
gene id: 1863:CKV89_RS11165
uniprot id: A0A239VVB5
names: Similarity
messages: Belongs to the flagella basal body rod proteins family.

1863:CKV89 RS00240
gene id: 1863:CKV89_RS00240
uniprot id: A0A239V379
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

1863:CKV89 RS07935
gene id: 1863:CKV89_RS07935
uniprot id: A0A239VLH6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PdxS/SNZ family.
messages: Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively.
messages: In the presence of PdxT, forms a dodecamer of heterodimers.

1863:CKV89 RS08670
gene id: 1863:CKV89_RS08670
uniprot id: A0A239VNZ6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

1863:CKV89 RS01420
gene id: 1863:CKV89_RS01420
uniprot id: A0A239V7W4
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

1863:CKV89 RS07230
gene id: 1863:CKV89_RS07230
uniprot id: A0A239VL83
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase class-2 family.
messages: Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.

1863:CKV89 RS08060
gene id: 1863:CKV89_RS08060
uniprot id: A0A239VMF8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

1863:CKV89 RS04735
gene id: 1863:CKV89_RS04735
uniprot id: A0A239VFG1
names: Similarity
messages: Belongs to the methylmalonyl-CoA epimerase family.

1863:CKV89 RS10700
gene id: 1863:CKV89_RS10700
uniprot id: A0A239VTR5
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.

1863:CKV89 RS01790
gene id: 1863:CKV89_RS01790
uniprot id: A0A239V7C5
names: Similarity
messages: Belongs to the YciI family.

1863:CKV89 RS05435
gene id: 1863:CKV89_RS05435
uniprot id: A0A239VFW4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ArgR family.
messages: Cytoplasm
messages: Regulates arginine biosynthesis genes.

1863:CKV89 RS03695
gene id: 1863:CKV89_RS03695
uniprot id: A0A239VC17
names: Function
names: Similarity
messages: Belongs to the LDH/MDH superfamily. MDH type 2 family.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.

1863:CKV89 RS01145
gene id: 1863:CKV89_RS01145
uniprot id: A0A239V5U0
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.

1863:CKV89 RS05455
gene id: 1863:CKV89_RS05455
uniprot id: A0A239VFD0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CbiN family.
messages: Cell membrane
messages: Forms an energy-coupling factor (ECF) transporter complex composed of an ATP-binding protein (A component, CbiO), a transmembrane protein (T component, CbiQ) and 2 possible substrate-capture proteins (S components, CbiM and CbiN) of unknown stoichimetry.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import.

1863:CKV89 RS09620
gene id: 1863:CKV89_RS09620
uniprot id: A0A239VPB0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

1863:CKV89 RS00220
gene id: 1863:CKV89_RS00220
uniprot id: A0A9Q2YTE3
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1863:CKV89 RS05030
gene id: 1863:CKV89_RS05030
uniprot id: A0A239VFJ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

1863:CKV89 RS05910
gene id: 1863:CKV89_RS05910
uniprot id: A0A239VGF9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1863:CKV89 RS06795
gene id: 1863:CKV89_RS06795
uniprot id: A0A239VJ96
names: Similarity
messages: Belongs to the disproportionating enzyme family.

1863:CKV89 RS03490
gene id: 1863:CKV89_RS03490
uniprot id: A0A239VB99
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1863:CKV89 RS06060
gene id: 1863:CKV89_RS06060
uniprot id: A0A239VH36
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

1863:CKV89 RS06375
gene id: 1863:CKV89_RS06375
uniprot id: A0A239VJ98
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HPF/YfiA ribosome-associated protein family. Long HPF subfamily.
messages: Cytoplasm
messages: Interacts with 100S ribosomes.
messages: Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth.

1863:CKV89 RS03815
gene id: 1863:CKV89_RS03815
uniprot id: A0A239VDX6
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

1863:CKV89 RS03020
gene id: 1863:CKV89_RS03020
uniprot id: A0A239VCA5
names: Subcellular Location Annotation
messages: Membrane

1863:CKV89 RS09565
gene id: 1863:CKV89_RS09565
uniprot id: A0A9Q2UDI4
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1863:CKV89 RS01045
gene id: 1863:CKV89_RS01045
uniprot id: A0A239V5K1
names: Similarity
messages: Belongs to the citrate synthase family.

1863:CKV89 RS10380
gene id: 1863:CKV89_RS10380
uniprot id: A0A239VT95
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1863:CKV89 RS11355
gene id: 1863:CKV89_RS11355
uniprot id: A0A239VWM3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

1863:CKV89 RS00795
gene id: 1863:CKV89_RS00795
uniprot id: A0A239V4S2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AzlC family.
messages: Membrane

1863:CKV89 RS12565
gene id: 1863:CKV89_RS12565
uniprot id: A0A239VQU3
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

1863:CKV89 RS10400
gene id: 1863:CKV89_RS10400
uniprot id: A0A239VT12
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

1863:CKV89 RS09425
gene id: 1863:CKV89_RS09425
uniprot id: A0A239VPI6
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

1863:CKV89 RS03860
gene id: 1863:CKV89_RS03860
uniprot id: A0A239VE06
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1863:CKV89 RS00015
gene id: 1863:CKV89_RS00015
uniprot id: A0A239V2S4
names: Function
messages: Catalyzes the phosphorylation of hydroxymethylpyrimidine phosphate (HMP-P) to HMP-PP, and of HMP to HMP-P.

1863:CKV89 RS06115
gene id: 1863:CKV89_RS06115
uniprot id: A0A239VH78
names: Cofactor
names: Similarity
messages: Belongs to the PyrK family.
messages: Binds 1 FAD per subunit.
messages: Binds 1 [2Fe-2S] cluster per subunit.

1863:CKV89 RS04965
gene id: 1863:CKV89_RS04965
uniprot id: A0A239VF35
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
messages: Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
messages: Cytoplasm

1863:CKV89 RS02550
gene id: 1863:CKV89_RS02550
uniprot id: A0A239VAY2
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-I 3-dehydroquinase family.
messages: Homodimer.
messages: Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3-dehydroshikimate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1863:CKV89 RS04710
gene id: 1863:CKV89_RS04710
uniprot id: A0A239VDL3
names: Similarity
messages: Belongs to the Cob(I)alamin adenosyltransferase family.

1863:CKV89 RS02935
gene id: 1863:CKV89_RS02935
uniprot id: A0A239VBB6
names: Function
names: Similarity
messages: Belongs to the aspartokinase family.
messages: Catalyzes the phosphorylation of the beta-carboxyl group of aspartic acid with ATP to yield 4-phospho-L-aspartate, which is involved in the branched biosynthetic pathway leading to the biosynthesis of amino acids lysine, threonine, isoleucine and methionine.

1863:CKV89 RS05065
gene id: 1863:CKV89_RS05065
uniprot id: A0A239VEE2
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

1863:CKV89 RS07360
gene id: 1863:CKV89_RS07360
uniprot id: A0A239VLD6
names: Function
names: Similarity
messages: Belongs to the HrcA family.
messages: Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons.

1863:CKV89 RS03390
gene id: 1863:CKV89_RS03390
uniprot id: A0A239VD28
names: Caution
names: Function
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family. MenB subfamily.
messages: Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2-naphthoyl-CoA (DHNA-CoA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1863:CKV89 RS06715
gene id: 1863:CKV89_RS06715
uniprot id: A0A239VJF8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

1863:CKV89 RS08250
gene id: 1863:CKV89_RS08250
uniprot id: A0A239VMG3
names: Similarity
messages: Belongs to the Pup ligase/Pup deamidase family. Pup deamidase subfamily.

1863:CKV89 RS07465
gene id: 1863:CKV89_RS07465
uniprot id: A0A239VJU7
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

1863:CKV89 RS07510
gene id: 1863:CKV89_RS07510
uniprot id: A0A239VJT9
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

1863:CKV89 RS08935
gene id: 1863:CKV89_RS08935
uniprot id: A0A239VP35
names: Subcellular Location Annotation
messages: Membrane

1863:CKV89 RS10360
gene id: 1863:CKV89_RS10360
uniprot id: A0A239VRI9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Cytoplasm
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

1863:CKV89 RS00575
gene id: 1863:CKV89_RS00575
uniprot id: A0A239V457
names: Similarity
messages: Belongs to the peptidase M18 family.

1863:CKV89 RS08615
gene id: 1863:CKV89_RS08615
uniprot id: A0A239VLX4
names: Similarity
names: Subunit
messages: Belongs to the transketolase family.
messages: Homodimer.

1863:CKV89 RS04910
gene id: 1863:CKV89_RS04910
uniprot id: A0A239VDW6
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1863:CKV89 RS09645
gene id: 1863:CKV89_RS09645
uniprot id: A0A239VQQ1
names: Cofactor
names: Function
messages: Binds 1 [3Fe-4S] cluster.
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

1863:CKV89 RS05780
gene id: 1863:CKV89_RS05780
uniprot id: A0A239VHV6
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

1863:CKV89 RS03575
gene id: 1863:CKV89_RS03575
uniprot id: A0A239VBN3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DcuA/DcuB transporter (TC 2.A.13.1) family.
messages: Cell inner membrane
messages: Membrane

1863:CKV89 RS11465
gene id: 1863:CKV89_RS11465
uniprot id: A0A239VV12
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

1863:CKV89 RS03525
gene id: 1863:CKV89_RS03525
uniprot id: A0A239VC52
names: Similarity
messages: Belongs to the cytochrome P450 family.

1863:CKV89 RS00290
gene id: 1863:CKV89_RS00290
uniprot id: A0A239V4V7
names: Similarity
messages: Belongs to the lysine N(6)-hydroxylase/L-ornithine N(5)-oxygenase family.

1863:CKV89 RS11145
gene id: 1863:CKV89_RS11145
uniprot id: A0A239VVE5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliL family.
messages: Cell membrane
messages: Controls the rotational direction of flagella during chemotaxis.
messages: Membrane

1863:CKV89 RS06530
gene id: 1863:CKV89_RS06530
uniprot id: A0A239VJN8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAL/histidase family.
messages: Cytoplasm

1863:CKV89 RS06920
gene id: 1863:CKV89_RS06920
uniprot id: A0A239VIK8
names: Subcellular Location Annotation
messages: Membrane

1863:CKV89 RS05595
gene id: 1863:CKV89_RS05595
uniprot id: A0A239VHG6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein uL14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein uL14 (rplN).

1863:CKV89 RS04390
gene id: 1863:CKV89_RS04390
uniprot id: A0A239VEI4
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ArgK/MeaB subfamily.

1863:CKV89 RS06575
gene id: 1863:CKV89_RS06575
uniprot id: A0A239VJQ1
names: Function
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.
messages: Provides the (R)-glutamate required for cell wall biosynthesis.

1863:CKV89 RS02320
gene id: 1863:CKV89_RS02320
uniprot id: A0A239V991
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoenolpyruvate carboxykinase [GTP] family.
messages: Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1863:CKV89 RS04105
gene id: 1863:CKV89_RS04105
uniprot id: A0A239VCH0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KdpC family.
messages: Cell membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

1863:CKV89 RS00405
gene id: 1863:CKV89_RS00405
uniprot id: A0A239V5U9
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.

1863:CKV89 RS00335
gene id: 1863:CKV89_RS00335
uniprot id: A0A239V604
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

1863:CKV89 RS09630
gene id: 1863:CKV89_RS09630
uniprot id: A0A239VR46
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type 2 tetrahydrodipicolinate N-succinyltransferase family.
messages: Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2-amino-6-oxopimelate using succinyl-CoA.
messages: Cytoplasm
messages: Homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1863:CKV89 RS07755
gene id: 1863:CKV89_RS07755
uniprot id: A0A239VK83
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

1863:CKV89 RS02655
gene id: 1863:CKV89_RS02655
uniprot id: A0A239V9M9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

1863:CKV89 RS10280
gene id: 1863:CKV89_RS10280
uniprot id: A0A239VSJ6
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

1863:CKV89 RS04085
gene id: 1863:CKV89_RS04085
uniprot id: A0A239VCG3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Amino acid transporter (AAT) (TC 2.A.3.1) family.
messages: Membrane

1863:CKV89 RS01110
gene id: 1863:CKV89_RS01110
uniprot id: A0A239V5S3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nlpA lipoprotein family.
messages: Membrane

1863:CKV89 RS07000
gene id: 1863:CKV89_RS07000
uniprot id: A0A239VK78
names: Subcellular Location Annotation
messages: Membrane

1863:CKV89 RS09840
gene id: 1863:CKV89_RS09840
uniprot id: A0A239VQ00
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

1863:CKV89 RS02435
gene id: 1863:CKV89_RS02435
uniprot id: A0A239V8W1
names: Similarity
messages: Belongs to the peptidase S1 family.

1863:CKV89 RS00325
gene id: 1863:CKV89_RS00325
uniprot id: A0A239V5L3
names: Similarity
messages: Belongs to the cytochrome P450 family.

1863:CKV89 RS05820
gene id: 1863:CKV89_RS05820
uniprot id: A0A239VGH8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1863:CKV89 RS03365
gene id: 1863:CKV89_RS03365
uniprot id: A0A239VAZ4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MenA family. Type 1 subfamily.
messages: Cell membrane
messages: Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK).
messages: Membrane

1863:CKV89 RS05685
gene id: 1863:CKV89_RS05685
uniprot id: A0A239VG79
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SepF family.
messages: Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA.
messages: Cytoplasm
messages: Homodimer. Interacts with FtsZ.

1863:CKV89 RS02615
gene id: 1863:CKV89_RS02615
uniprot id: A0A239VAP7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TerC family.
messages: Membrane

1863:CKV89 RS03000
gene id: 1863:CKV89_RS03000
uniprot id: A0A239VAS7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

1863:CKV89 RS09865
gene id: 1863:CKV89_RS09865
uniprot id: A0A239VR76
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1863:CKV89 RS08035
gene id: 1863:CKV89_RS08035
uniprot id: A0A239VLZ1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

1863:CKV89 RS02290
gene id: 1863:CKV89_RS02290
uniprot id: A0A239VAC4
names: Similarity
messages: Belongs to the 6-phosphogluconate dehydrogenase family.

1863:CKV89 RS06170
gene id: 1863:CKV89_RS06170
uniprot id: A0A239VHB0
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.

1863:CKV89 RS04795
gene id: 1863:CKV89_RS04795
uniprot id: A0A239VEZ4
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta subunit.
messages: The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase).

1863:CKV89 RS11505
gene id: 1863:CKV89_RS11505
uniprot id: A0A239VX49
names: Cofactor
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.
messages: Probably binds two magnesium or manganese ions per subunit.

1863:CKV89 RS08385
gene id: 1863:CKV89_RS08385
uniprot id: A0A239VNC2
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

1863:CKV89 RS03670
gene id: 1863:CKV89_RS03670
uniprot id: A0A239VBS2
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

1863:CKV89 RS11460
gene id: 1863:CKV89_RS11460
uniprot id: A0A239VUW3
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1863:CKV89 RS08750
gene id: 1863:CKV89_RS08750
uniprot id: A0A239VNP9
names: Similarity
names: Subunit
messages: Belongs to the pyruvate kinase family.
messages: Homotetramer.

1863:CKV89 RS08875
gene id: 1863:CKV89_RS08875
uniprot id: A0A239VPG6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

1863:CKV89 RS00465
gene id: 1863:CKV89_RS00465
uniprot id: A0A239V5E6
names: Subcellular Location Annotation
messages: Membrane

1863:CKV89 RS05660
gene id: 1863:CKV89_RS05660
uniprot id: A0A239VH42
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

1863:CKV89 RS09895
gene id: 1863:CKV89_RS09895
uniprot id: A0A239VQ26
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

1863:CKV89 RS00725
gene id: 1863:CKV89_RS00725
uniprot id: A0A239V6R8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Membrane

1863:CKV89 RS05270
gene id: 1863:CKV89_RS05270
uniprot id: A0A239VGB0
names: Similarity
messages: Belongs to the UPF0102 family.

1863:CKV89 RS11210
gene id: 1863:CKV89_RS11210
uniprot id: A0A239VU29
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliG family.
messages: Membrane

1863:CKV89 RS08290
gene id: 1863:CKV89_RS08290
uniprot id: A0A239VL68
names: Function
messages: TetR is the repressor of the tetracycline resistance element; its N-terminal region forms a helix-turn-helix structure and binds DNA. Binding of tetracycline to TetR reduces the repressor affinity for the tetracycline resistance gene (tetA) promoter operator sites.

1863:CKV89 RS06620
gene id: 1863:CKV89_RS06620
uniprot id: A0A239VJT0
names: Similarity
messages: Belongs to the GroES chaperonin family.

1863:CKV89 RS09225
gene id: 1863:CKV89_RS09225
uniprot id: A0A239VQ65
names: Subcellular Location Annotation
messages: Membrane

1863:CKV89 RS10015
gene id: 1863:CKV89_RS10015
uniprot id: A0A239VQH9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1863:CKV89 RS08725
gene id: 1863:CKV89_RS08725
uniprot id: A0A239VMC7
names: Function
names: Similarity
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.

1863:CKV89 RS00140
gene id: 1863:CKV89_RS00140
uniprot id: A0A239V5B3
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

1863:CKV89 RS04605
gene id: 1863:CKV89_RS04605
uniprot id: A0A239VDJ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase A chain family.
messages: Cell membrane
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

1863:CKV89 RS01885
gene id: 1863:CKV89_RS01885
uniprot id: A0A239V7H9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UreF family.
messages: Cytoplasm
messages: Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
messages: UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

1863:CKV89 RS10345
gene id: 1863:CKV89_RS10345
uniprot id: A0A239VRK5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaD and TsaB. TsaE seems to play an indirect role in the t(6)A biosynthesis pathway, possibly in regulating the core enzymatic function of TsaD.

1863:CKV89 RS06000
gene id: 1863:CKV89_RS06000
uniprot id: A0A239VIN3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

1863:CKV89 RS04810
gene id: 1863:CKV89_RS04810
uniprot id: A0A239VF08
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1863:CKV89 RS02140
gene id: 1863:CKV89_RS02140
uniprot id: A0A239V871
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

1863:CKV89 RS09925
gene id: 1863:CKV89_RS09925
uniprot id: A0A239VRF4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

1863:CKV89 RS11300
gene id: 1863:CKV89_RS11300
uniprot id: A0A239VVS5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliS family.
messages: cytosol

1863:CKV89 RS06775
gene id: 1863:CKV89_RS06775
uniprot id: A0A239VIC7
names: Subcellular Location Annotation
messages: Membrane

1863:CKV89 RS08400
gene id: 1863:CKV89_RS08400
uniprot id: A0A239VLD9
names: Similarity
messages: Belongs to the UPF0098 family.

1863:CKV89 RS01520
gene id: 1863:CKV89_RS01520
uniprot id: A0A239V738
names: Subcellular Location Annotation
messages: Membrane

1863:CKV89 RS03425
gene id: 1863:CKV89_RS03425
uniprot id: A0A239VBZ0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

1863:CKV89 RS03705
gene id: 1863:CKV89_RS03705
uniprot id: A0A239VCH1
names: Cofactor
names: Similarity
messages: Belongs to the monomeric-type IDH family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

1863:CKV89 RS00980
gene id: 1863:CKV89_RS00980
uniprot id: A0A239V685
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1863:CKV89 RS06430
gene id: 1863:CKV89_RS06430
uniprot id: A0A239VHR9
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

1863:CKV89 RS03415
gene id: 1863:CKV89_RS03415
uniprot id: A0A239VBJ5
names: Subcellular Location Annotation
messages: Membrane

1863:CKV89 RS04435
gene id: 1863:CKV89_RS04435
uniprot id: A0A239VD88
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cell surface
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
messages: capsule
messages: cell wall

1863:CKV89 RS02295
gene id: 1863:CKV89_RS02295
uniprot id: A0A239V8G9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

1863:CKV89 RS06935
gene id: 1863:CKV89_RS06935
uniprot id: A0A239VJW8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

1863:CKV89 RS07905
gene id: 1863:CKV89_RS07905
uniprot id: A0A239VMA3
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1863:CKV89 RS04915
gene id: 1863:CKV89_RS04915
uniprot id: A0A239VFJ4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1863:CKV89 RS10155
gene id: 1863:CKV89_RS10155
uniprot id: A0A239VQU4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

1863:CKV89 RS11120
gene id: 1863:CKV89_RS11120
uniprot id: A0A239VTU5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliQ/MopD/SpaQ family.
messages: Membrane

1863:CKV89 RS04580
gene id: 1863:CKV89_RS04580
uniprot id: A0A239VE79
names: Function
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

1863:CKV89 RS09990
gene id: 1863:CKV89_RS09990
uniprot id: A0A239VS35
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

1863:CKV89 RS04905
gene id: 1863:CKV89_RS04905
uniprot id: A0A9Q2UBB3
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1863:CKV89 RS09780
gene id: 1863:CKV89_RS09780
uniprot id: A0A239VPV6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1863:CKV89 RS05640
gene id: 1863:CKV89_RS05640
uniprot id: A0A239VFX1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane
messages: Membrane

1863:CKV89 RS11495
gene id: 1863:CKV89_RS11495
uniprot id: A0A239VVE8
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1863:CKV89 RS00010
gene id: 1863:CKV89_RS00010
uniprot id: A0A239V2R3
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1863:CKV89 RS05515
gene id: 1863:CKV89_RS05515
uniprot id: A0A239VG28
names: Similarity
messages: Belongs to the ribF family.

1863:CKV89 RS03175
gene id: 1863:CKV89_RS03175
uniprot id: A0A239VAN9
names: Similarity
messages: Belongs to the DNA glycosylase MPG family.

1863:CKV89 RS11170
gene id: 1863:CKV89_RS11170
uniprot id: A0A239VTZ8
names: Similarity
messages: Belongs to the flagella basal body rod proteins family.

1863:CKV89 RS06745
gene id: 1863:CKV89_RS06745
uniprot id: A0A239VJ67
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

1863:CKV89 RS03560
gene id: 1863:CKV89_RS03560
uniprot id: A0A239VC75
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1863:CKV89 RS02940
gene id: 1863:CKV89_RS02940
uniprot id: A0A239V9W7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HAK/KUP transporter (TC 2.A.72) family.
messages: Cell membrane
messages: Membrane
messages: Transport of potassium into the cell. Likely operates as a K(+):H(+) symporter.

1863:CKV89 RS04545
gene id: 1863:CKV89_RS04545
uniprot id: A0A239VDB8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

1863:CKV89 RS01220
gene id: 1863:CKV89_RS01220
uniprot id: A0A239V5Z0
names: Subcellular Location Annotation
messages: Membrane

1863:CKV89 RS09995
gene id: 1863:CKV89_RS09995
uniprot id: A0A9Q2UEQ6
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.
messages: With S4 and S5 plays an important role in translational accuracy.

1863:CKV89 RS09640
gene id: 1863:CKV89_RS09640
uniprot id: A0A239VRB5
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1863:CKV89 RS03645
gene id: 1863:CKV89_RS03645
uniprot id: A0A239VBL9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

1863:CKV89 RS07985
gene id: 1863:CKV89_RS07985
uniprot id: A0A239VMG8
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

1863:CKV89 RS00760
gene id: 1863:CKV89_RS00760
uniprot id: A0A239V582
names: Subcellular Location Annotation
messages: Membrane

1863:CKV89 RS05120
gene id: 1863:CKV89_RS05120
uniprot id: A0A239VFX9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

1863:CKV89 RS07585
gene id: 1863:CKV89_RS07585
uniprot id: A0A239VJX5
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1863:CKV89 RS11275
gene id: 1863:CKV89_RS11275
uniprot id: A0A239VWD5
names: Function
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. Fucose synthase subfamily.
messages: Catalyzes the two-step NADP-dependent conversion of GDP-4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction.

1863:CKV89 RS11415
gene id: 1863:CKV89_RS11415
uniprot id: A0A239VUT1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

1863:CKV89 RS07950
gene id: 1863:CKV89_RS07950
uniprot id: A0A239VLS5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

1863:CKV89 RS08605
gene id: 1863:CKV89_RS08605
uniprot id: A0A239VNU1
names: Subcellular Location Annotation
messages: Membrane

1863:CKV89 RS04955
gene id: 1863:CKV89_RS04955
uniprot id: A0A239VEC4
names: Function
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.

1863:CKV89 RS02585
gene id: 1863:CKV89_RS02585
uniprot id: A0A239V9A3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

1863:CKV89 RS03825
gene id: 1863:CKV89_RS03825
uniprot id: A0A239VBX4
names: Similarity
messages: Belongs to the glycerate kinase type-1 family.

1863:CKV89 RS11440
gene id: 1863:CKV89_RS11440
uniprot id: A0A239VUV8
names: Similarity
messages: Belongs to the SAICAR synthetase family.

1863:CKV89 RS00740
gene id: 1863:CKV89_RS00740
uniprot id: A0A239V4U4
names: Subcellular Location Annotation
messages: Membrane

1863:CKV89 RS09835
gene id: 1863:CKV89_RS09835
uniprot id: A0A239VRK8
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

1863:CKV89 RS10885
gene id: 1863:CKV89_RS10885
uniprot id: A0A239VV42
names: Similarity
messages: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.

1863:CKV89 RS05465
gene id: 1863:CKV89_RS05465
uniprot id: A0A239VFJ8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Part of an ABC transporter complex. Responsible for energy coupling to the transport system.

1863:CKV89 RS01545
gene id: 1863:CKV89_RS01545
uniprot id: A0A239V8P8
names: Similarity
messages: Belongs to the ThrE exporter (TC 2.A.79) family.

1863:CKV89 RS01060
gene id: 1863:CKV89_RS01060
uniprot id: A0A239V5M4
names: Similarity
messages: Belongs to the XFP family.

1863:CKV89 RS08950
gene id: 1863:CKV89_RS08950
uniprot id: A0A239VPN5
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

1863:CKV89 RS00670
gene id: 1863:CKV89_RS00670
uniprot id: A0A239V4L4
names: Similarity
messages: Belongs to the TelA family.

1863:CKV89 RS10005
gene id: 1863:CKV89_RS10005
uniprot id: A0A239VRQ8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1863:CKV89 RS03630
gene id: 1863:CKV89_RS03630
uniprot id: A0A239VBR4
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

1863:CKV89 RS06080
gene id: 1863:CKV89_RS06080
uniprot id: A0A239VHY0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm

1863:CKV89 RS11225
gene id: 1863:CKV89_RS11225
uniprot id: A0A239VW64
names: Similarity
messages: Belongs to the flagella basal body rod proteins family.

1863:CKV89 RS05790
gene id: 1863:CKV89_RS05790
uniprot id: A0A239VG71
names: Cofactor
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.
messages: Probably binds two magnesium or manganese ions per subunit.

1863:CKV89 RS09965
gene id: 1863:CKV89_RS09965
uniprot id: A0A239VS97
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

1863:CKV89 RS01685
gene id: 1863:CKV89_RS01685
uniprot id: A0A239V718
names: Subcellular Location Annotation
messages: Membrane

1863:CKV89 RS10240
gene id: 1863:CKV89_RS10240
uniprot id: A0A239VSH3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Membrane

1863:CKV89 RS07275
gene id: 1863:CKV89_RS07275
uniprot id: A0A239VJI4
names: Similarity
messages: Belongs to the IMPACT family.

1863:CKV89 RS04800
gene id: 1863:CKV89_RS04800
uniprot id: A0A239VFA8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ETF alpha-subunit/FixB family.
messages: Binds 1 FAD per dimer.
messages: Heterodimer of an alpha and a beta subunit.
messages: The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase).

1863:CKV89 RS04960
gene id: 1863:CKV89_RS04960
uniprot id: A0A239VE01
names: Similarity
names: Subunit
messages: Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.
messages: Homodimer.

1863:CKV89 RS01190
gene id: 1863:CKV89_RS01190
uniprot id: A0A239V5S5
names: Similarity
messages: Belongs to the glucose-6-phosphate 1-epimerase family.

1863:CKV89 RS07960
gene id: 1863:CKV89_RS07960
uniprot id: A0A239VKN9
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvA family.
messages: Cytoplasm
messages: Has three domains with a flexible linker between the domains II and III and assumes an 'L' shape. Domain III is highly mobile and contacts RuvB.
messages: Homotetramer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

1863:CKV89 RS00225
gene id: 1863:CKV89_RS00225
uniprot id: A0A239V429
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell membrane
messages: Membrane

1863:CKV89 RS03040
gene id: 1863:CKV89_RS03040
uniprot id: A0A239VAD5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.
messages: Binds 2 iron ions per subunit.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.
messages: Tetramer of two alpha and two beta subunits.

1863:CKV89 RS08120
gene id: 1863:CKV89_RS08120
uniprot id: A0A239VMK4
names: Similarity
messages: Belongs to the peptidase S49 family.

1863:CKV89 RS00030
gene id: 1863:CKV89_RS00030
uniprot id: A0A239V4G7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Amino acid transporter (AAT) (TC 2.A.3.1) family.
messages: Membrane

1863:CKV89 RS05710
gene id: 1863:CKV89_RS05710
uniprot id: A0A239VG95
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm

1863:CKV89 RS03715
gene id: 1863:CKV89_RS03715
uniprot id: A0A239VBW6
names: Cofactor
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.
messages: Probably binds two magnesium or manganese ions per subunit.

1863:CKV89 RS00900
gene id: 1863:CKV89_RS00900
uniprot id: A0A239V551
names: Cofactor
messages: Binds 4 [4Fe-4S] clusters per subunit.

1863:CKV89 RS10350
gene id: 1863:CKV89_RS10350
uniprot id: A0A239VT59
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.

1863:CKV89 RS06940
gene id: 1863:CKV89_RS06940
uniprot id: A0A239VKS7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

1863:CKV89 RS01410
gene id: 1863:CKV89_RS01410
uniprot id: A0A239V7V2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
messages: Membrane

1863:CKV89 RS03610
gene id: 1863:CKV89_RS03610
uniprot id: A0A239VBJ0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I fumarase family.
messages: Catalyzes the reversible hydration of fumarate to (S)-malate.
messages: Homodimer.

1863:CKV89 RS00550
gene id: 1863:CKV89_RS00550
uniprot id: A0A239V423
names: Subcellular Location Annotation
messages: Membrane

1863:CKV89 RS04195
gene id: 1863:CKV89_RS04195
uniprot id: A0A239VEJ7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

1863:CKV89 RS10275
gene id: 1863:CKV89_RS10275
uniprot id: A0A239VRC1
names: Function
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.

1863:CKV89 RS10270
gene id: 1863:CKV89_RS10270
uniprot id: A0A239VR94
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the complex I 75 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1863:CKV89 RS00005
gene id: 1863:CKV89_RS00005
uniprot id: A0A239V2V2
names: Caution
names: Function
names: Similarity
messages: Belongs to the Thz kinase family.
messages: Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1863:CKV89 RS03850
gene id: 1863:CKV89_RS03850
uniprot id: A0A239VDL0
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.
messages: Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.
messages: Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
messages: Cytoplasm
messages: Homodimer.
messages: Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate.

1863:CKV89 RS06200
gene id: 1863:CKV89_RS06200
uniprot id: A0A239VIZ2
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

1863:CKV89 RS05615
gene id: 1863:CKV89_RS05615
uniprot id: A0A239VGJ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

1863:CKV89 RS10590
gene id: 1863:CKV89_RS10590
uniprot id: A0A239VU51
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

1863:CKV89 RS09915
gene id: 1863:CKV89_RS09915
uniprot id: A0A239VRX9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

1863:CKV89 RS05390
gene id: 1863:CKV89_RS05390
uniprot id: A0A239VGF1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.
messages: Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.
messages: Cytoplasm
messages: Homodimer.

1863:CKV89 RS12555
gene id: 1863:CKV89_RS12555
uniprot id: A0A239VNQ8
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

1863:CKV89 RS01445
gene id: 1863:CKV89_RS01445
uniprot id: A0A239V744
names: Caution
names: Similarity
messages: Belongs to the globin family.
messages: In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1863:CKV89 RS10100
gene id: 1863:CKV89_RS10100
uniprot id: A0A239VS92
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PNT beta subunit family.
messages: Cell inner membrane
messages: Membrane
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

1863:CKV89 RS07740
gene id: 1863:CKV89_RS07740
uniprot id: A0A239VK81
names: Function
names: Similarity
messages: Belongs to the IMPDH/GMPR family. GuaB1 subfamily.
messages: Involved in the purine-salvage pathway. Catalyzes the NADPH-dependent conversion of GMP to IMP.

1863:CKV89 RS08435
gene id: 1863:CKV89_RS08435
uniprot id: A0A239VLQ0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
messages: Homotetramer.
messages: Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc.

1863:CKV89 RS05395
gene id: 1863:CKV89_RS05395
uniprot id: A0A239VGK6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase H family.
messages: Binds 1 Mg(2+) ion per subunit. May bind a second metal ion at a regulatory site, or after substrate binding.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Monomer.

1863:CKV89 RS02915
gene id: 1863:CKV89_RS02915
uniprot id: A0A239VA16
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

1863:CKV89 RS11115
gene id: 1863:CKV89_RS11115
uniprot id: A0A239VTV3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliR/MopE/SpaR family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Role in flagellar biosynthesis.

1863:CKV89 RS00415
gene id: 1863:CKV89_RS00415
uniprot id: A0A239V5V9
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

1863:CKV89 RS06445
gene id: 1863:CKV89_RS06445
uniprot id: A0A239VI26
names: Similarity
messages: Belongs to the universal stress protein A family.

1863:CKV89 RS04780
gene id: 1863:CKV89_RS04780
uniprot id: A0A239VEY3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 13 family. GlgE subfamily.
messages: Homodimer.
messages: Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1->4)-glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB.

1863:CKV89 RS11400
gene id: 1863:CKV89_RS11400
uniprot id: A0A239VWB4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as an anti-CsrA protein, binds CsrA and prevents it from repressing translation of its target genes, one of which is flagellin. Binds to flagellin and participates in the assembly of the flagellum.
messages: Belongs to the FliW family.
messages: Cytoplasm
messages: Interacts with translational regulator CsrA and flagellin(s).

1863:CKV89 RS09215
gene id: 1863:CKV89_RS09215
uniprot id: A0A239VPK9
names: PTM
names: Subcellular Location Annotation
names: Subunit
messages: Binds 2 heme c groups covalently per subunit.
messages: Cell membrane
messages: Membrane
messages: The cytochrome bc1 complex is composed of a cytochrome b (QcrB), the Rieske iron-sulfur protein (QcrA) and a diheme cytochrome c (QcrC) subunit.

1863:CKV89 RS01555
gene id: 1863:CKV89_RS01555
uniprot id: A0A239V6T7
names: Subcellular Location Annotation
messages: Membrane

1863:CKV89 RS08050
gene id: 1863:CKV89_RS08050
uniprot id: A0A239VM01
names: Function
names: Similarity
names: Subunit
messages: Belongs to the polyphosphate kinase 2 (PPK2) family. Class I subfamily.
messages: Homotetramer.
messages: Uses inorganic polyphosphate (polyP) as a donor to convert GDP to GTP or ADP to ATP.

1863:CKV89 RS07560
gene id: 1863:CKV89_RS07560
uniprot id: A0A239VLB5
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

1863:CKV89 RS09200
gene id: 1863:CKV89_RS09200
uniprot id: A0A239VQC7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1863:CKV89 RS07975
gene id: 1863:CKV89_RS07975
uniprot id: A0A239VLZ2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

1863:CKV89 RS01635
gene id: 1863:CKV89_RS01635
uniprot id: A0A239V701
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Catalyzes the sodium-dependent uptake of extracellular L-proline.
messages: Cell membrane
messages: Membrane

1863:CKV89 RS06850
gene id: 1863:CKV89_RS06850
uniprot id: A0A239VJR3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 2 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

1863:CKV89 RS02055
gene id: 1863:CKV89_RS02055
uniprot id: A0A239V9D0
names: Subcellular Location Annotation
messages: Membrane

1863:CKV89 RS08560
gene id: 1863:CKV89_RS08560
uniprot id: A0A239VNH6
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.

1863:CKV89 RS09210
gene id: 1863:CKV89_RS09210
uniprot id: A0A239VP27
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Membrane

1863:CKV89 RS05885
gene id: 1863:CKV89_RS05885
uniprot id: A0A239VH13
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1863:CKV89 RS09385
gene id: 1863:CKV89_RS09385
uniprot id: A0A239VQJ9
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

1863:CKV89 RS02780
gene id: 1863:CKV89_RS02780
uniprot id: A0A239V9M6
names: Similarity
messages: Belongs to the CobT family.

1863:CKV89 RS06590
gene id: 1863:CKV89_RS06590
uniprot id: A0A239VJA1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

1863:CKV89 RS05870
gene id: 1863:CKV89_RS05870
uniprot id: A0A239VHY9
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1863:CKV89 RS06305
gene id: 1863:CKV89_RS06305
uniprot id: A0A239VIC9
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

1863:CKV89 RS04620
gene id: 1863:CKV89_RS04620
uniprot id: A0A239VEX7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase delta chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

1863:CKV89 RS03440
gene id: 1863:CKV89_RS03440
uniprot id: A0A239VBD1
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

1863:CKV89 RS04395
gene id: 1863:CKV89_RS04395
uniprot id: A0A239VDV0
names: Subunit
messages: Heterodimer of an alpha and a beta chain.

1863:CKV89 RS10200
gene id: 1863:CKV89_RS10200
uniprot id: A0A239VR22
names: Similarity
messages: Belongs to the asparaginase 1 family.

1863:CKV89 RS03565
gene id: 1863:CKV89_RS03565
uniprot id: A0A239VC72
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

1863:CKV89 RS01525
gene id: 1863:CKV89_RS01525
uniprot id: A0A239V6Q9
names: Similarity
messages: Belongs to the DapA family.

1863:CKV89 RS03330
gene id: 1863:CKV89_RS03330
uniprot id: A0A239VAW2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

1863:CKV89 RS07575
gene id: 1863:CKV89_RS07575
uniprot id: A0A239VL98
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).

1863:CKV89 RS04405
gene id: 1863:CKV89_RS04405
uniprot id: A0A239VEJ0
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

1863:CKV89 RS12095
gene id: 1863:CKV89_RS12095
uniprot id: A0A239V4B8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

1863:CKV89 RS02410
gene id: 1863:CKV89_RS02410
uniprot id: A0A239V9H8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptide transporter carbon starvation (CstA) (TC 2.A.114) family.
messages: Membrane

1863:CKV89 RS10010
gene id: 1863:CKV89_RS10010
uniprot id: A0A239VS28
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

1863:CKV89 RS01295
gene id: 1863:CKV89_RS01295
uniprot id: A0A239V6L9
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane
messages: Membrane

1863:CKV89 RS05370
gene id: 1863:CKV89_RS05370
uniprot id: A0A239VEV4
names: Subcellular Location Annotation
messages: Membrane

1863:CKV89 RS04310
gene id: 1863:CKV89_RS04310
uniprot id: A0A239VEP0
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1863:CKV89 RS03955
gene id: 1863:CKV89_RS03955
uniprot id: A0A239VCY4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

1863:CKV89 RS02795
gene id: 1863:CKV89_RS02795
uniprot id: A0A239VA04
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

1863:CKV89 RS09220
gene id: 1863:CKV89_RS09220
uniprot id: A0A239VQ04
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Rieske iron-sulfur protein family.
messages: Cell membrane
messages: Iron-sulfur subunit of the cytochrome bc1 complex, an essential component of the respiratory electron transport chain required for ATP synthesis. The bc1 complex catalyzes the oxidation of menaquinol and the reduction of cytochrome c in the respiratory chain. The bc1 complex operates through a Q-cycle mechanism that couples electron transfer to generation of the proton gradient that drives ATP synthesis.

1863:CKV89 RS10520
gene id: 1863:CKV89_RS10520
uniprot id: A0A239VTV6
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. GDP-mannose 4,6-dehydratase subfamily.
messages: Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6-deoxy-D-mannose.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1863:CKV89 RS00515
gene id: 1863:CKV89_RS00515
uniprot id: A0A239V4G2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

1863:CKV89 RS10165
gene id: 1863:CKV89_RS10165
uniprot id: A0A239VSJ1
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type B subfamily.
messages: Part of the 50S ribosomal subunit.

1863:CKV89 RS00810
gene id: 1863:CKV89_RS00810
uniprot id: A0A239V7G2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FdhD family.
messages: Cytoplasm
messages: Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH.

1863:CKV89 RS06980
gene id: 1863:CKV89_RS06980
uniprot id: A0A239VK70
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1863:CKV89 RS05760
gene id: 1863:CKV89_RS05760
uniprot id: A0A239VHZ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DcuA/DcuB transporter (TC 2.A.13.1) family.
messages: Cell inner membrane
messages: Membrane

1863:CKV89 RS11410
gene id: 1863:CKV89_RS11410
uniprot id: A0A9Q2UE34
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1863:CKV89 RS06320
gene id: 1863:CKV89_RS06320
uniprot id: A0A239VJ83
names: Similarity
messages: Belongs to the phosphohexose mutase family.

1863:CKV89 RS06385
gene id: 1863:CKV89_RS06385
uniprot id: A0A239VIJ3
names: Similarity
messages: Belongs to the peptidase S8 family.

1863:CKV89 RS04095
gene id: 1863:CKV89_RS04095
uniprot id: A0A239VEF0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KdpA family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds the extracellular potassium ions and delivers the ions to the membrane domain of KdpB through an intramembrane tunnel.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

1863:CKV89 RS04240
gene id: 1863:CKV89_RS04240
uniprot id: A0A239VCT1
names: Caution
names: Cofactor
names: Domain
names: Function
names: Similarity
messages: Belongs to the nitrobindin family.
messages: Binds 1 heme b group per subunit, that coordinates a highly solvent-exposed Fe(III) atom.
messages: Forms a 10-stranded antiparallel beta-barrel structure able to accommodate a hydrophobic ligand in its interior. In fact, this fold hosts the heme group, which is located in a wide surface cleft.
messages: Heme-binding protein able to scavenge peroxynitrite and to protect free L-tyrosine against peroxynitrite-mediated nitration, by acting as a peroxynitrite isomerase that converts peroxynitrite to nitrate. Therefore, this protein likely plays a role in peroxynitrite sensing and in the detoxification of reactive nitrogen and oxygen species (RNS and ROS, respectively). Is able to bind nitric oxide (NO) in vitro, but may act as a sensor of peroxynitrite levels in vivo.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1863:CKV89 RS06835
gene id: 1863:CKV89_RS06835
uniprot id: A0A9Q2YU30
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1863:CKV89 RS01165
gene id: 1863:CKV89_RS01165
uniprot id: A0A239V689
names: Similarity
messages: To bacterial alkanal monooxygenase alpha and beta chains.

1863:CKV89 RS05245
gene id: 1863:CKV89_RS05245
uniprot id: A0A239VFR9
names: Similarity
messages: Belongs to the DyP-type peroxidase family.

1863:CKV89 RS11475
gene id: 1863:CKV89_RS11475
uniprot id: A0A239VVC5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class II fructose-bisphosphate aldolase family.
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.
messages: Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.

1863:CKV89 RS10195
gene id: 1863:CKV89_RS10195
uniprot id: A0A239VSA6
names: Similarity
messages: Belongs to the UPF0234 family.

1863:CKV89 RS09360
gene id: 1863:CKV89_RS09360
uniprot id: A0A239VQQ4
names: Similarity
messages: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.

1863:CKV89 RS11135
gene id: 1863:CKV89_RS11135
uniprot id: A0A239VV36
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliN/MopA/SpaO family.
messages: Membrane

1863:CKV89 RS02725
gene id: 1863:CKV89_RS02725
uniprot id: A0A239VAZ1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ThiG family.
messages: Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
messages: Cytoplasm
messages: Homotetramer. Forms heterodimers with either ThiH or ThiS.

1863:CKV89 RS08705
gene id: 1863:CKV89_RS08705
uniprot id: A0A239VNU8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

1863:CKV89 RS01455
gene id: 1863:CKV89_RS01455
uniprot id: A0A239V6L1
names: Function
names: Similarity
messages: Belongs to the AlaDH/PNT family.
messages: Catalyzes the reversible reductive amination of pyruvate to L-alanine.

1863:CKV89 RS03030
gene id: 1863:CKV89_RS03030
uniprot id: A0A239VBU3
names: Function
names: Similarity
messages: Belongs to the NrdI family.
messages: Probably involved in ribonucleotide reductase function.

1863:CKV89 RS06165
gene id: 1863:CKV89_RS06165
uniprot id: A0A239VIW8
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

1863:CKV89 RS06650
gene id: 1863:CKV89_RS06650
uniprot id: A0A239VHZ1
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.

1863:CKV89 RS04770
gene id: 1863:CKV89_RS04770
uniprot id: A0A239VF88
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aminoglycoside phosphotransferase family.
messages: Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
messages: Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.
messages: Monomer.

1863:CKV89 RS04425
gene id: 1863:CKV89_RS04425
uniprot id: A0A239VEU7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1863:CKV89 RS03865
gene id: 1863:CKV89_RS03865
uniprot id: A0A239VC61
names: Caution
names: Function
names: Similarity
messages: Belongs to the bacterial two-domain DSD family.
messages: Catalyzes the conversion of 3-dehydroshikimate to protocatechuate (3,4-dihydroxybenzoate), a common intermediate of quinate and shikimate degradation pathways.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1863:CKV89 RS04945
gene id: 1863:CKV89_RS04945
uniprot id: A0A239VF16
names: Similarity
messages: Belongs to the SorC transcriptional regulatory family.

1863:CKV89 RS04650
gene id: 1863:CKV89_RS04650
uniprot id: A0A239VEZ6
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

1863:CKV89 RS00645
gene id: 1863:CKV89_RS00645
uniprot id: A0A239V4F2
names: Subcellular Location Annotation
messages: Membrane

1863:CKV89 RS01995
gene id: 1863:CKV89_RS01995
uniprot id: A0A239V7V0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1863:CKV89 RS00200
gene id: 1863:CKV89_RS00200
uniprot id: A0A239V3J9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the branched chain amino acid transporter family.
messages: Membrane